Gene Ontology Enrichment Results

Homer de novo Motif Enrichment Results
Known Motif Enrichment Results

Text file version of complete results (i.e. open with Excel)

Enriched Categories

P-valueln(P)TermGO TreeGO ID# of Genes in Term# of Target Genes in Term# of Total Genes# of Target GenesCommon Genes
4.641e-07-14.58cytoplasmcellular componentGO:000573712081471910850 FNIP1,MEF2C,SH2B3,STAB1,DOCK4,ADGRG3,FMNL1,RBM47,DAB2,DISC1,TFEB,BLNK,GLDC,RXRA,CD68,MYO1F,ETS1,FLRT2,ARHGAP45,MICAL2,CSF3R,MARK4,ARHGEF1,ABCC5,MAN1A1,CERT1,FCHO2,RHBDF1,MLKL,SRGN,RGL1,AOX1,ARAP1,SGMS1,SH3KBP1,CD53,HCK,ABCA1,FERMT3,CTSV,DIAPH2,CEBPB,ATP8A1,ETV6,MFSD1,PLEK,ARAP3
9.747e-07-13.84INPP5D (inositol polyphosphate-5-phosphatase D)protein interactions36357051945450 CSF3R,ARAP1,DAB2,HCK,SH3KBP1
3.398e-06-12.59lysosomecellular componentGO:0005764762111910850 ARHGAP45,SRGN,CSF3R,TFEB,DAB2,CTSV,CD68,ATP8A1,MFSD1,HCK,FNIP1
3.398e-06-12.59lytic vacuolecellular componentGO:0000323762111910850 FNIP1,HCK,MFSD1,ATP8A1,CD68,CTSV,DAB2,TFEB,CSF3R,SRGN,ARHGAP45
4.793e-06-12.25signalingbiological processGO:00230524968291820450 MARK4,CERT1,SH2B3,FNIP1,BLNK,HCK,CSF3R,ARAP3,STAB1,ABCA1,SH3KBP1,ARHGEF1,MEF2C,DOCK4,ARAP1,ADGRG3,RGL1,SRGN,FERMT3,CD276,CD53,MLKL,RXRA,CEBPB,ARHGAP45,PLEK,DAB2,FLRT2,DISC1
5.749e-06-12.07cell communicationbiological processGO:00071545010291820450 FNIP1,SH2B3,BLNK,CERT1,MARK4,ABCA1,SH3KBP1,HCK,ARAP3,CSF3R,STAB1,ARHGEF1,MEF2C,RGL1,ADGRG3,FERMT3,SRGN,CD276,DOCK4,ARAP1,MLKL,CD53,RXRA,CEBPB,ARHGAP45,PLEK,FLRT2,DISC1,DAB2
5.833e-06-12.05lymph_nodeCOSMIC cancer mutationslymph_node1703161682846 MARK4,FLRT2,HCK,ABCA1,ETV6,MEF2C,GLDC,FNIP1,ATP8A1,AOX1,ELF4,MLKL,ARAP3,ETS1,BLNK,SH3KBP1
6.001e-06-12.02cellular response to stimulusbiological processGO:00517166307331820450 RGL1,ADGRG3,SRGN,FERMT3,CD276,ABCC5,DOCK4,ARAP1,TFEB,MAN1A1,MEF2C,ARHGEF1,CD68,ABCA1,HCK,AOX1,ARAP3,CSF3R,SH2B3,FNIP1,BLNK,CERT1,MARK4,FLRT2,DISC1,DAB2,GLDC,PLEK,CEBPB,ARHGAP45,CD53,MLKL,RXRA
6.474e-06-11.95Inppl1 (inositol polyphosphate phosphatase-like 1)protein interactions16332221945450 SH3KBP1,ARAP3
6.866e-06-11.89PH_domaininterpro domainsIPR00184926671852150 SH2B3,CERT1,PLEK,ARAP1,ARAP3,FERMT3,ARHGEF1
7.027e-06-11.87haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-angioimmunoblastic_T_cell_lymphomaCOSMIC cancer mutationshaematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-angioimmunoblastic_T_cell_lymphoma26571682846 SH2B3,ETS1,HCK,ETV6,MICAL2,MEF2C,BLNK
7.750e-06-11.77angioimmunoblastic_T_cell_lymphomaCOSMIC cancer mutationsangioimmunoblastic_T_cell_lymphoma26971682846 SH2B3,ETS1,HCK,MICAL2,ETV6,BLNK,MEF2C
9.204e-06-11.60cytoplasmic vesiclecellular componentGO:00314102521191910850 ADGRG3,MAN1A1,ABCC5,STAB1,FCHO2,FMNL1,DAB2,SRGN,DISC1,FERMT3,ABCA1,CD53,HCK,SH3KBP1,ATP8A1,CD68,DIAPH2,CSF3R,ARHGAP45
9.531e-06-11.56intracellular vesiclecellular componentGO:00977082527191910850 CSF3R,ARHGAP45,ABCA1,FERMT3,SH3KBP1,HCK,CD53,ATP8A1,DIAPH2,CD68,DAB2,DISC1,SRGN,STAB1,MAN1A1,ABCC5,ADGRG3,FCHO2,FMNL1
1.039e-05-11.47vacuolecellular componentGO:0005773857111910850 CSF3R,TFEB,ARHGAP45,SRGN,DAB2,ATP8A1,MFSD1,CTSV,CD68,HCK,FNIP1
1.193e-05-11.34SH3KBP1 (SH3 domain containing kinase binding protein 1)protein interactions3001130471945450 HCK,ARAP1,BLNK,SH3KBP1,DAB2,ARAP3,ARHGEF1
1.194e-05-11.34PHpfam domainsPF0016918761779549 ARAP3,PLEK,FERMT3,SH2B3,CERT1,ARAP1
1.538e-05-11.08signal transductionbiological processGO:00071654637271820450 ARHGAP45,CEBPB,RXRA,CD53,MLKL,DAB2,DISC1,FLRT2,PLEK,CSF3R,ARAP3,HCK,ABCA1,MARK4,CERT1,BLNK,SH2B3,FNIP1,ARAP1,DOCK4,CD276,SRGN,FERMT3,RGL1,ADGRG3,MEF2C,ARHGEF1
1.732e-05-10.96plasma membranecellular componentGO:00058865538291910850 FLRT2,CD276,ARHGAP45,CSF3R,CD68,MYO1F,DAB2,GLDC,BLNK,SH2B3,ADGRG3,STAB1,DOCK4,FMNL1,ARAP3,PLEK,HCK,CD53,ARAP1,SH3KBP1,SGMS1,ABCA1,ETV6,ATP8A1,MLKL,RGL1,ARHGEF1,ABCC5,FCHO2
1.762e-05-10.95SAM/pointed_sfinterpro domainsIPR01376112051852150 ETV6,ARAP1,SGMS1,ETS1,ARAP3
1.837e-05-10.90PH-like_dom_sfinterpro domainsIPR01199343181852150 ARAP3,DAB2,ARHGEF1,FERMT3,SH2B3,CERT1,ARAP1,PLEK
2.139e-05-10.75RhoGAP_ARAPinterpro domainsIPR037858321852150 ARAP3,ARAP1
2.783e-05-10.49skin-trunk-malignant_melanoma-nodularCOSMIC cancer mutationsskin-trunk-malignant_melanoma-nodular1291131682846 BLNK,DISC1,ATP8A1,MICAL2,PLEK,ARAP3,FMNL1,CSF3R,TFEB,RBM47,STAB1,MAN1A1,SRGN
2.839e-05-10.47response to stimulusbiological processGO:00508967803361820450 CD68,MEF2C,ARHGEF1,MAN1A1,DOCK4,TFEB,ARAP1,ABCC5,CD276,ADGRG3,RGL1,SRGN,FERMT3,CERT1,MARK4,BLNK,SH2B3,FNIP1,CSF3R,ARAP3,STAB1,HCK,AOX1,ABCA1,PLEK,CTSV,GLDC,DAB2,DISC1,FLRT2,ETS1,RXRA,MLKL,CD53,ARHGAP45,CEBPB
3.415e-05-10.28Transcription Factor, Ets-1gene3d domains1.10.150.5011551447047 ARAP3,SGMS1,ARAP1,ETS1,ETV6
4.348e-05-10.04NHLRC2 (NHL repeat containing 2)protein interactions37435437271945450 PLEK,ARHGEF1,FERMT3,SH3KBP1,FMNL1,TFEB,MYO1F
4.939e-05-9.92trunkCOSMIC cancer mutationstrunk3554221682846 TFEB,RBM47,SRGN,AOX1,CSF3R,FMNL1,ARAP3,DAB2,MYO1F,MICAL2,ABCC5,BLNK,SH3KBP1,MAN1A1,STAB1,HCK,FLRT2,PLEK,ABCA1,GLDC,ATP8A1,DISC1
5.483e-05-9.81PHsmart domainsSM002332597971738 ARAP1,FERMT3,CERT1,ARHGEF1,PLEK,ARAP3,SH2B3
5.783e-05-9.76Ets_dominterpro domainsIPR0004182831852150 ETS1,ETV6,ELF4
5.783e-05-9.76ETS_faminterpro domainsIPR0463282831852150 ETS1,ELF4,ETV6
6.084e-05-9.71cellular processbiological processGO:000998714996501820450 BAZ2B,GLDC,CTSV,ELF4,DIAPH2,DISC1,RXRA,ARHGAP45,ETV6,CD68,MAN1A1,RHBDF1,DOCK4,FCHO2,ABCC5,CD276,RGL1,FMNL1,SRGN,FERMT3,RBM47,MARK4,BLNK,SH2B3,STAB1,HCK,AOX1,SH3KBP1,PLEK,MICAL2,DAB2,SGMS1,FLRT2,ETS1,MLKL,CD53,CEBPB,ATP8A1,MEF2C,MYO1F,ARHGEF1,ARAP1,TFEB,MFSD1,ADGRG3,CERT1,FNIP1,CSF3R,ARAP3,ABCA1
6.124e-05-9.70Etspfam domainsPF001782831779549 ETV6,ELF4,ETS1
6.583e-05-9.63Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)gene3d domains2.30.29.3043181447047 DAB2,CERT1,PLEK,ARHGEF1,FERMT3,SH2B3,ARAP3,ARAP1
6.876e-05-9.58oesophagus-carcinoma-squamous_cell_carcinomaCOSMIC cancer mutationsoesophagus-carcinoma-squamous_cell_carcinoma6486311682846 FNIP1,GLDC,DISC1,RHBDF1,HCK,FLRT2,ABCA1,BAZ2B,CD53,ARHGEF1,MYO1F,ARAP3,ELF4,RXRA,CD276,MFSD1,ATP8A1,FERMT3,ETV6,MAN1A1,ARAP1,SH3KBP1,DIAPH2,DAB2,MICAL2,ABCC5,CSF3R,ETS1,DOCK4,TFEB,AOX1
9.059e-05-9.31positive regulation of lipid transportbiological processGO:00323708641820450 RXRA,ABCA1,DAB2,ATP8A1
9.321e-05-9.28hemopoiesisbiological processGO:003009768891820450 ADGRG3,ETV6,CEBPB,BLNK,SH2B3,FNIP1,PLEK,RBM47,MEF2C
9.616e-05-9.25cell peripherycellular componentGO:00719446020291910850 ARHGEF1,ABCC5,FCHO2,MLKL,RGL1,HCK,CD53,SGMS1,SH3KBP1,ARAP1,ABCA1,ETV6,ATP8A1,ARAP3,PLEK,SH2B3,ADGRG3,STAB1,DOCK4,FMNL1,DAB2,BLNK,GLDC,CD68,MYO1F,FLRT2,ARHGAP45,CD276,CSF3R
9.715e-05-9.24enzyme bindingmolecular functionGO:00198992086161809450 RXRA,MLKL,RBM47,CEBPB,MICAL2,MEF2C,BLNK,SH3KBP1,DIAPH2,FMNL1,FNIP1,TFEB,PLEK,DOCK4,SH2B3,ABCA1
1.106e-04-9.11RApfam domainsPF007883431779549 ARAP3,RGL1,ARAP1
1.153e-04-9.07ETS_DOMAIN_2prosite domainsPS003462631218645 ETS1,ETV6,ELF4
1.389e-04-8.88integrin-mediated signaling pathwaybiological processGO:00072299641820450 PLEK,DAB2,HCK,FERMT3
1.445e-04-8.84ETS_DOMAIN_3prosite domainsPS500612831218645 ELF4,ETV6,ETS1
1.455e-04-8.84nodularCOSMIC cancer mutationsnodular1515131682846 STAB1,MAN1A1,PLEK,DISC1,ATP8A1,SRGN,TFEB,RBM47,FMNL1,ARAP3,CSF3R,MICAL2,BLNK
1.455e-04-8.84cytosolcellular componentGO:00058295475271910850 FCHO2,CERT1,ARHGEF1,MAN1A1,MLKL,AOX1,RGL1,DIAPH2,ETV6,ATP8A1,HCK,ARAP1,SH3KBP1,PLEK,FMNL1,FNIP1,SH2B3,MEF2C,DOCK4,DISC1,BLNK,TFEB,DAB2,RXRA,MYO1F,ARHGAP45,MARK4
1.492e-04-8.81intracellular anatomical structurecellular componentGO:000562215205491910850 MYO1F,MICAL2,CSF3R,ETS1,RBM47,FNIP1,STAB1,DOCK4,DISC1,GLDC,BLNK,DAB2,DIAPH2,BAZ2B,HCK,ARAP1,SGMS1,ABCA1,ARAP3,PLEK,CERT1,ARHGEF1,ABCC5,MLKL,RHBDF1,CD68,RXRA,ARHGAP45,FLRT2,MARK4,FMNL1,MEF2C,SH2B3,ADGRG3,TFEB,CEBPB,CTSV,MFSD1,ETV6,ATP8A1,CD53,SH3KBP1,FERMT3,FCHO2,ELF4,MAN1A1,SRGN,AOX1,RGL1
1.511e-04-8.80lytic vacuole membranecellular componentGO:009885244671910850 CSF3R,TFEB,DAB2,CD68,ATP8A1,MFSD1,FNIP1
1.511e-04-8.80lysosomal membranecellular componentGO:000576544671910850 CSF3R,TFEB,DAB2,CD68,ATP8A1,MFSD1,FNIP1
1.580e-04-8.75RA_dominterpro domainsIPR0001593931852150 ARAP3,RGL1,ARAP1
1.690e-04-8.69ETSsmart domainsSM00413283971738 ETS1,ELF4,ETV6
1.823e-04-8.61regulation of biomineral tissue developmentbiological processGO:007016710341820450 RXRA,SRGN,CEBPB,MEF2C
1.824e-04-8.61KIT (KIT proto-oncogene, receptor tyrosine kinase)protein interactions381511041945450 SH3KBP1,HCK,BLNK,SH2B3
1.858e-04-8.59skin-mucosal-malignant_melanomaCOSMIC cancer mutationsskin-mucosal-malignant_melanoma2009151682846 HCK,GLDC,ATP8A1,ETV6,MLKL,CSF3R,ARAP3,TFEB,RBM47,ELF4,RXRA,AOX1,SH3KBP1,DAB2,MICAL2
1.858e-04-8.59mucosalCOSMIC cancer mutationsmucosal2009151682846 HCK,ETV6,GLDC,ATP8A1,TFEB,RBM47,ELF4,RXRA,AOX1,MLKL,CSF3R,ARAP3,DAB2,MICAL2,SH3KBP1
1.873e-04-8.58positive regulation of cellular component organizationbiological processGO:00511301122111820450 CD53,FNIP1,MARK4,ATP8A1,PLEK,FLRT2,ABCA1,DISC1,HCK,DAB2,ARAP1
1.978e-04-8.53immune system processbiological processGO:00023761991151820450 CEBPB,HCK,CSF3R,ETS1,CERT1,FNIP1,SH2B3,BLNK,TFEB,ADGRG3,CD276,MEF2C,CTSV,CD68,ELF4
1.979e-04-8.53DAD_dominterpro domainsIPR014767821852150 DIAPH2,FMNL1
2.039e-04-8.50CRKL (CRK like proto-oncogene, adaptor protein)protein interactions139921151945450 AOX1,BLNK,ETV6,SH3KBP1,HCK
2.062e-04-8.49regulation of response to stimulusbiological processGO:00485834104231820450 MARK4,ETS1,RBM47,FNIP1,SH2B3,RXRA,BLNK,HCK,CEBPB,ARHGAP45,ABCA1,CTSV,MEF2C,ARHGEF1,PLEK,ELF4,RHBDF1,DAB2,ARAP1,SGMS1,ADGRG3,DISC1,CD276
2.110e-04-8.46positive regulation of protein-containing complex assemblybiological processGO:003133419951820450 HCK,MARK4,PLEK,ABCA1,FNIP1
2.161e-04-8.44CAPZA1 (capping actin protein of muscle Z-line subunit alpha 1)protein interactions82933761945450 BLNK,ARAP1,DISC1,SH3KBP1,ARHGEF1,RXRA
2.204e-04-8.42central_nervous_system-brain-primitive_neuroectodermal_tumour-medulloblastomaCOSMIC cancer mutationscentral_nervous_system-brain-primitive_neuroectodermal_tumour-medulloblastoma7205321682846 SRGN,AOX1,ETS1,CSF3R,DOCK4,DIAPH2,DAB2,RGL1,MICAL2,ABCC5,SH3KBP1,MARK4,MAN1A1,ARAP1,STAB1,SGMS1,ETV6,MFSD1,ATP8A1,SH2B3,ELF4,RXRA,MLKL,ARAP3,MYO1F,CD53,BLNK,BAZ2B,PLEK,ABCA1,FNIP1,GLDC
2.270e-04-8.39ETSDOMAINprints domainsPR00454283522723 ETV6,ELF4,ETS1
2.429e-04-8.32positive regulation of lipid localizationbiological processGO:190595411141820450 ATP8A1,DAB2,ABCA1,RXRA
2.540e-04-8.28GTPase-bdinterpro domainsIPR010473921852150 FMNL1,DIAPH2
2.540e-04-8.28FH3_dominterpro domainsIPR010472921852150 DIAPH2,FMNL1
2.641e-04-8.24Drf_FH3pfam domainsPF06367921779549 DIAPH2,FMNL1
2.641e-04-8.24Drf_GBDpfam domainsPF06371921779549 DIAPH2,FMNL1
2.661e-04-8.23phosphatidylserine floppase activitymolecular functionGO:0090556921809450 ABCA1,ATP8A1
2.681e-04-8.22PH_DOMAINprosite domainsPS5000324661218645 ARHGEF1,PLEK,CERT1,ARAP1,FERMT3,ARAP3
2.687e-04-8.22vacuolar membranecellular componentGO:000577449071910850 ATP8A1,MFSD1,CD68,FNIP1,CSF3R,TFEB,DAB2
2.736e-04-8.20regulation of developmental processbiological processGO:00507932540171820450 MEF2C,ARAP1,DAB2,DISC1,FMNL1,SRGN,FLRT2,ETS1,RXRA,FNIP1,CD53,STAB1,CSF3R,CEBPB,HCK,SH3KBP1,ABCA1
3.349e-04-8.00RAprosite domainsPS502003731218645 RGL1,ARAP1,ARAP3
3.456e-04-7.97ARHGEF1 (Rho guanine nucleotide exchange factor 1)protein interactions913813041945450 PLEK,DOCK4,ARHGEF1,SH3KBP1
3.508e-04-7.96PLEK (pleckstrin)protein interactions53411121945450 ARHGEF1,PLEK
3.681e-04-7.91DADprosite domainsPS51231821218645 DIAPH2,FMNL1
3.737e-04-7.89oesophagus-lower_third-carcinoma-adenocarcinomaCOSMIC cancer mutationsoesophagus-lower_third-carcinoma-adenocarcinoma6302291682846 MYO1F,RXRA,ELF4,SH2B3,MLKL,DISC1,FCHO2,GLDC,BAZ2B,ABCA1,FLRT2,ABCC5,MICAL2,RGL1,DIAPH2,DAB2,AOX1,SRGN,TFEB,DOCK4,FMNL1,ETS1,CSF3R,ATP8A1,CD276,SGMS1,STAB1,ARAP1,MAN1A1
3.868e-04-7.86GBD/FH3_dominterpro domainsIPR0147681121852150 FMNL1,DIAPH2
3.868e-04-7.86Pointed_dominterpro domainsIPR0031181121852150 ETV6,ETS1
4.013e-04-7.82endocytosisbiological processGO:000689749971820450 FCHO2,DAB2,STAB1,HCK,MYO1F,SH3KBP1,ABCA1
4.021e-04-7.82SAM_PNTpfam domainsPF021981121779549 ETV6,ETS1
4.059e-04-7.81ITSN1 (intersectin 1)protein interactions645324551945450 DOCK4,SH3KBP1,DISC1,DAB2,FCHO2
4.382e-04-7.73positive regulation of biomineral tissue developmentbiological processGO:00701695431820450 RXRA,CEBPB,MEF2C
4.848e-04-7.63positive regulation of cellular component biogenesisbiological processGO:004408951571820450 MARK4,PLEK,FNIP1,HCK,ARAP1,ABCA1,FLRT2
4.982e-04-7.60acute_lymphoblastic_leukaemiaCOSMIC cancer mutationsacute_lymphoblastic_leukaemia2197151682846 DAB2,BLNK,ARHGEF1,TFEB,AOX1,MLKL,CSF3R,FMNL1,ETV6,MEF2C,MAN1A1,MARK4,STAB1,BAZ2B,HCK
4.990e-04-7.60thyroid-carcinomaCOSMIC cancer mutationsthyroid-carcinoma4126221682846 STAB1,ARAP1,MAN1A1,ABCC5,RGL1,SH3KBP1,AOX1,FMNL1,DOCK4,ETS1,CSF3R,MEF2C,FNIP1,BAZ2B,ABCA1,PLEK,FLRT2,RXRA,ELF4,SH2B3,RBM47,ARAP3
5.179e-04-7.57lipid bindingmolecular functionGO:000828986191809450 ABCA1,ARAP1,BLNK,RXRA,HCK,ARAP3,FERMT3,CERT1,FCHO2
5.269e-04-7.55Drf_GBDsmart domainsSM0114092971738 FMNL1,DIAPH2
5.269e-04-7.55Drf_FH3smart domainsSM0113992971738 DIAPH2,FMNL1
5.273e-04-7.55anion bindingmolecular functionGO:00431682412161809450 MYO1F,MICAL2,RXRA,GLDC,AOX1,ARAP3,ATP8A1,HCK,MLKL,ABCC5,CERT1,PLEK,MARK4,ABCA1,ARAP1,FCHO2
5.563e-04-7.49membranecellular componentGO:00160209220361910850 RGL1,MLKL,RHBDF1,CERT1,FCHO2,MAN1A1,ABCC5,ARHGEF1,PLEK,ARAP3,ATP8A1,MFSD1,ETV6,ABCA1,FERMT3,SH3KBP1,ARAP1,SGMS1,HCK,CD53,BLNK,TFEB,GLDC,DAB2,FMNL1,DOCK4,STAB1,ADGRG3,FNIP1,SH2B3,CSF3R,CD276,FLRT2,ARHGAP45,MYO1F,CD68
5.709e-04-7.47regulation of cell shapebiological processGO:000836013941820450 ARAP1,HCK,SH3KBP1,FMNL1
6.026e-04-7.41signaling receptor bindingmolecular functionGO:00051021493121809450 DAB2,DOCK4,SH2B3,ABCA1,ARAP1,ARHGEF1,FLRT2,DIAPH2,FERMT3,BLNK,HCK,CD276
6.132e-04-7.40intracellular signal transductionbiological processGO:00355561505121820450 MARK4,ARHGEF1,MEF2C,PLEK,FNIP1,SH2B3,BLNK,HCK,CEBPB,DOCK4,RGL1,DISC1
6.362e-04-7.36programmed cell deathbiological processGO:00125011087101820450 MEF2C,CTSV,FNIP1,MLKL,CEBPB,ETV6,DAB2,SRGN,SGMS1,SH3KBP1
6.547e-04-7.33cell deathbiological processGO:00082191091101820450 SH3KBP1,SRGN,SGMS1,DAB2,CEBPB,ETV6,FNIP1,MLKL,MEF2C,CTSV
6.816e-04-7.29ASAP1 (ArfGAP with SH3 domain, ankyrin repeat and PH domain 1)protein interactions508076731945450 SH3KBP1,HCK,ARAP3
6.933e-04-7.27actin cytoskeleton organizationbiological processGO:003003654771820450 SH3KBP1,FMNL1,ARAP1,DIAPH2,PLEK,MICAL2,MYO1F
7.006e-04-7.26cell surface receptor signaling pathwaybiological processGO:00071661992141820450 MEF2C,PLEK,ADGRG3,FLRT2,FERMT3,CD276,DISC1,DAB2,MLKL,SH2B3,BLNK,ABCA1,HCK,CSF3R
7.082e-04-7.25GRB2 (growth factor receptor bound protein 2)protein interactions288576981945450 SH2B3,CSF3R,SH3KBP1,DAB2,DOCK4,ETV6,BLNK,ARAP1
7.180e-04-7.24PNTprosite domainsPS514331121218645 ETV6,ETS1
7.180e-04-7.24GBD_FH3prosite domainsPS512321121218645 DIAPH2,FMNL1
7.188e-04-7.24RhoGAP_dominterpro domainsIPR0001986531852150 ARAP3,ARHGAP45,ARAP1
7.333e-04-7.22FH2_Formin_sfinterpro domainsIPR0422011521852150 DIAPH2,FMNL1
7.333e-04-7.22FH2_Formininterpro domainsIPR0154251521852150 DIAPH2,FMNL1
7.347e-04-7.22phospholipid transporter activitymolecular functionGO:00055486431809450 CERT1,ABCA1,ATP8A1
7.426e-04-7.21cell activationbiological processGO:000177572581820450 MEF2C,PLEK,FNIP1,BLNK,ELF4,FERMT3,ADGRG3,CD276
7.601e-04-7.18RhoGAPpfam domainsPF006206531779549 ARAP1,ARHGAP45,ARAP3
7.623e-04-7.18FH2pfam domainsPF021811521779549 DIAPH2,FMNL1
7.983e-04-7.13regulation of lipid transportbiological processGO:003236815241820450 ABCA1,RXRA,DAB2,ATP8A1
8.011e-04-7.13SAM_PNTsmart domainsSM00251112971738 ETS1,ETV6
8.181e-04-7.11organophosphate ester transportbiological processGO:001574815341820450 ABCA1,ABCC5,CERT1,ATP8A1
8.563e-04-7.06serous_carcinomaCOSMIC cancer mutationsserous_carcinoma10987401682846 TFEB,AOX1,CD68,DOCK4,CSF3R,ETS1,RGL1,DAB2,DIAPH2,ABCC5,MICAL2,SH3KBP1,STAB1,ARAP1,MAN1A1,MARK4,SGMS1,FERMT3,ETV6,CD276,MFSD1,ATP8A1,SH2B3,RBM47,RXRA,ELF4,MLKL,ARAP3,MYO1F,ARHGEF1,BAZ2B,PLEK,FLRT2,HCK,ABCA1,RHBDF1,MEF2C,GLDC,FNIP1,FCHO2
8.566e-04-7.06haematopoietic_and_lymphoid_tissue-lymph_node-lymphoid_neoplasm-acute_lymphoblastic_leukaemiaCOSMIC cancer mutationshaematopoietic_and_lymphoid_tissue-lymph_node-lymphoid_neoplasm-acute_lymphoblastic_leukaemia15641682846 HCK,BLNK,MEF2C,ETV6
8.761e-04-7.04floppase activitymolecular functionGO:01403281621809450 ABCA1,ATP8A1
9.171e-04-6.99GTPase activator activitymolecular functionGO:000509627351809450 ARAP3,ARHGAP45,DOCK4,ARHGEF1,ARAP1
9.470e-04-6.96HDAC9 (histone deacetylase 9)protein interactions97347531945450 CEBPB,MEF2C,ETV6
9.477e-04-6.96LMO7 (LIM domain 7)protein interactions400817041945450 RBM47,GLDC,FMNL1,ABCA1
9.511e-04-6.96haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-acute_lymphoblastic_leukaemiaCOSMIC cancer mutationshaematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-acute_lymphoblastic_leukaemia2081141682846 TFEB,AOX1,MLKL,FMNL1,CSF3R,DAB2,BLNK,ARHGEF1,BAZ2B,STAB1,MAN1A1,MARK4,HCK,ETV6
9.682e-04-6.94actin filament organizationbiological processGO:000701527851820450 DIAPH2,SH3KBP1,MYO1F,MICAL2,ARAP1
9.685e-04-6.94haematopoietic_and_lymphoid_tissue-haematopoietic_neoplasm-chronic_eosinophilic_leukaemia-hypereosinophilic_syndromeCOSMIC cancer mutationshaematopoietic_and_lymphoid_tissue-haematopoietic_neoplasm-chronic_eosinophilic_leukaemia-hypereosinophilic_syndrome1721682846 SH2B3,ETV6
9.685e-04-6.94chronic_eosinophilic_leukaemia-hypereosinophilic_syndromeCOSMIC cancer mutationschronic_eosinophilic_leukaemia-hypereosinophilic_syndrome1721682846 SH2B3,ETV6
9.694e-04-6.94vesiclecellular componentGO:00319824141211910850 ARHGAP45,FLRT2,CSF3R,CD68,DIAPH2,ATP8A1,HCK,CD53,SH3KBP1,FERMT3,ABCA1,SRGN,DISC1,AOX1,DAB2,FCHO2,FMNL1,MAN1A1,ADGRG3,ABCC5,STAB1
9.912e-04-6.92transmembrane receptor protein tyrosine kinase adaptor activitymolecular functionGO:00050681721809450 SH2B3,BLNK
1.033e-03-6.88regulation of multicellular organismal processbiological processGO:00512393113181820450 ETS1,RBM47,SH2B3,RXRA,CEBPB,CSF3R,STAB1,ABCA1,SH3KBP1,MEF2C,PLEK,ELF4,DOCK4,DAB2,FLRT2,SRGN,DISC1,CD276
1.055e-03-6.85Formin, FH2 domaingene3d domains1.20.58.22201521447047 FMNL1,DIAPH2
1.061e-03-6.85haematopoietic_and_lymphoid_tissue-haematopoietic_neoplasm-myelodysplastic_syndromeCOSMIC cancer mutationshaematopoietic_and_lymphoid_tissue-haematopoietic_neoplasm-myelodysplastic_syndrome1174101682846 MARK4,SH2B3,HCK,MLKL,CSF3R,DIAPH2,ETV6,MICAL2,FNIP1,BLNK
1.061e-03-6.85myelodysplastic_syndromeCOSMIC cancer mutationsmyelodysplastic_syndrome1174101682846 SH2B3,MARK4,MLKL,HCK,CSF3R,DIAPH2,ETV6,MICAL2,BLNK,FNIP1
1.078e-03-6.83cargo receptor activitymolecular functionGO:00380247331809450 STAB1,ABCA1,DAB2
1.100e-03-6.81clathrin coat assemblybiological processGO:00482681821820450 FCHO2,DAB2
1.100e-03-6.81Mercaptopurine Metabolism PathwaySMPDB pathwaysSMP000060915213695 ABCC5,AOX1
1.107e-03-6.81positive regulation of defense responsebiological processGO:003134943061820450 CEBPB,HCK,RBM47,MEF2C,ETS1,MARK4
1.152e-03-6.77bounding membrane of organellecellular componentGO:00985882198141910850 CSF3R,TFEB,RHBDF1,DAB2,CD68,ATP8A1,MFSD1,SGMS1,FNIP1,CD53,STAB1,ABCC5,MAN1A1,ADGRG3
1.221e-03-6.71enzyme activator activitymolecular functionGO:000804759971809450 DOCK4,ARHGAP45,ARAP3,FNIP1,CTSV,ARAP1,ARHGEF1
1.273e-03-6.67Rho GTPase activation proteingene3d domains1.10.555.106631447047 ARAP3,ARHGAP45,ARAP1
1.358e-03-6.60FH2prosite domainsPS514441521218645 FMNL1,DIAPH2
1.368e-03-6.59haematopoietic_and_lymphoid_tissue-haematopoietic_neoplasm-acute_myeloid_leukaemia_associated_with_MDSCOSMIC cancer mutationshaematopoietic_and_lymphoid_tissue-haematopoietic_neoplasm-acute_myeloid_leukaemia_associated_with_MDS17741682846 CSF3R,DOCK4,ETV6,SH2B3
1.368e-03-6.59acute_myeloid_leukaemia_associated_with_MDSCOSMIC cancer mutationsacute_myeloid_leukaemia_associated_with_MDS17741682846 DOCK4,CSF3R,ETV6,SH2B3
1.377e-03-6.59sphingolipid transporter activitymolecular functionGO:00466242021809450 ABCA1,CERT1
1.384e-03-6.58ovary-carcinoma-serous_carcinomaCOSMIC cancer mutationsovary-carcinoma-serous_carcinoma10710391682846 FCHO2,MEF2C,GLDC,FNIP1,RHBDF1,ABCA1,PLEK,FLRT2,HCK,BAZ2B,ARHGEF1,MYO1F,ARAP3,MLKL,RXRA,ELF4,SH2B3,RBM47,ATP8A1,CD276,ETV6,FERMT3,SGMS1,STAB1,ARAP1,MARK4,MAN1A1,SH3KBP1,ABCC5,MICAL2,RGL1,DAB2,DIAPH2,DOCK4,ETS1,CSF3R,AOX1,CD68,TFEB
1.385e-03-6.58actin filament-based processbiological processGO:003002961671820450 DIAPH2,PLEK,MICAL2,MYO1F,SH3KBP1,FMNL1,ARAP1
1.444e-03-6.54pharynxCOSMIC cancer mutationspharynx2696161682846 MEF2C,FNIP1,RHBDF1,FLRT2,SGMS1,STAB1,MARK4,ARHGEF1,ABCC5,MICAL2,DIAPH2,DAB2,DOCK4,ETS1,MLKL,SH2B3
1.455e-03-6.53FGR (FGR proto-oncogene, Src family tyrosine kinase)protein interactions22688731945450 HCK,SH3KBP1,DAB2
1.482e-03-6.51regulation of bone mineralizationbiological processGO:00305008231820450 SRGN,RXRA,MEF2C
1.491e-03-6.51thyroidCOSMIC cancer mutationsthyroid9867371682846 ARHGEF1,MYO1F,ARAP3,RXRA,ELF4,RBM47,SH2B3,FCHO2,MEF2C,GLDC,FNIP1,RHBDF1,ABCA1,FLRT2,PLEK,BAZ2B,SH3KBP1,ABCC5,MICAL2,RGL1,DAB2,DIAPH2,DOCK4,FMNL1,CSF3R,ETS1,CEBPB,AOX1,TFEB,ATP8A1,MFSD1,CD276,ETV6,STAB1,ARAP1,MAN1A1,MARK4
1.508e-03-6.50receptor tyrosine kinase bindingmolecular functionGO:00309718231809450 BLNK,DOCK4,SH2B3
1.514e-03-6.49FH2smart domainsSM00498152971738 DIAPH2,FMNL1
1.551e-03-6.47protein bindingmolecular functionGO:000551513983471809450 MFSD1,CEBPB,SH3KBP1,DISC1,CD276,GLDC,HCK,SH2B3,PLEK,MARK4,STAB1,FNIP1,MYO1F,RGL1,MEF2C,ARAP3,RHBDF1,RBM47,CD53,MLKL,DAB2,CTSV,ARAP1,TFEB,ELF4,ARHGAP45,BLNK,ETS1,AOX1,ADGRG3,RXRA,ETV6,DOCK4,CD68,DIAPH2,FCHO2,MICAL2,BAZ2B,ATP8A1,CSF3R,CERT1,ABCA1,FLRT2,ARHGEF1,FERMT3,SRGN,FMNL1
1.572e-03-6.46CD2AP (CD2 associated protein)protein interactions2360719541945450 ARAP3,BLNK,SH3KBP1,HCK
1.582e-03-6.45CD2 (CD2 molecule)protein interactions9142321945450 SH3KBP1,CD53
1.587e-03-6.45regulation of lipid localizationbiological processGO:190595218341820450 RXRA,ABCA1,ATP8A1,DAB2
1.705e-03-6.37positive regulation of multicellular organismal processbiological processGO:00512401691121820450 DAB2,FLRT2,DISC1,CD276,MEF2C,PLEK,CEBPB,ABCA1,SH3KBP1,ETS1,RBM47,RXRA
1.742e-03-6.35specific granule membranecellular componentGO:00355799131910850 CD53,ADGRG3,ATP8A1
1.743e-03-6.35FCH_dominterpro domainsIPR0010602321852150 ARHGAP45,FCHO2
1.752e-03-6.35RHOGAPprosite domainsPS502386531218645 ARAP1,ARAP3,ARHGAP45
1.775e-03-6.33lymphoid_neoplasmCOSMIC cancer mutationslymphoid_neoplasm12233421682846 SH3KBP1,MICAL2,ABCC5,DIAPH2,DAB2,RGL1,CSF3R,ETS1,FMNL1,DOCK4,SRGN,AOX1,TFEB,ATP8A1,CD276,MFSD1,ETV6,FERMT3,SGMS1,MARK4,MAN1A1,STAB1,ARAP1,ARHGEF1,CD53,BLNK,MYO1F,ARAP3,MLKL,ELF4,RXRA,RBM47,SH2B3,FNIP1,MEF2C,GLDC,RHBDF1,ABCA1,HCK,FLRT2,PLEK,BAZ2B
1.781e-03-6.33haematopoietic_and_lymphoid_tissue-lymph_node-lymphoid_neoplasm-mantle_cell_lymphomaCOSMIC cancer mutationshaematopoietic_and_lymphoid_tissue-lymph_node-lymphoid_neoplasm-mantle_cell_lymphoma47661682846 ATP8A1,FNIP1,GLDC,ETV6,ELF4,AOX1
1.783e-03-6.33biphasicCOSMIC cancer mutationsbiphasic8831682846 ETV6,SH2B3,FNIP1
1.785e-03-6.33B cell activationbiological processGO:004211318941820450 MEF2C,FNIP1,ADGRG3,BLNK
1.786e-03-6.33Rho GTPase cycleREACTOME pathwaysR-HSA-19484014241028538 ARAP3,ARAP1,ARHGAP45,ARHGEF1
1.829e-03-6.30RHOU (ras homolog family member U)protein interactions5848050761945450 PLEK,ABCC5,FMNL1,DAB2,FCHO2,FLRT2
1.844e-03-6.30Rho_GTPase_activation_protinterpro domainsIPR0089369031852150 ARAP3,ARAP1,ARHGAP45
1.857e-03-6.29cytoskeleton organizationbiological processGO:00070101251101820450 DIAPH2,MYO1F,MARK4,MICAL2,PLEK,FMNL1,SH3KBP1,DISC1,ARAP1,ARAP3
1.857e-03-6.29lymphocyte activationbiological processGO:004664947661820450 FNIP1,ADGRG3,BLNK,ELF4,CD276,MEF2C
1.859e-03-6.29apoptotic processbiological processGO:0006915103891820450 SH3KBP1,SGMS1,SRGN,DAB2,ETV6,CEBPB,FNIP1,CTSV,MEF2C
1.870e-03-6.28lower_thirdCOSMIC cancer mutationslower_third7961321682846 FCHO2,DISC1,MEF2C,GLDC,RHBDF1,ABCA1,FLRT2,BAZ2B,MYO1F,ARAP3,MLKL,ELF4,RXRA,SH2B3,ATP8A1,CD276,SGMS1,MAN1A1,ARAP1,STAB1,MICAL2,ABCC5,DIAPH2,DAB2,RGL1,ETS1,CSF3R,DOCK4,FMNL1,SRGN,AOX1,TFEB
1.893e-03-6.27stomach-carcinoma-intestinal_adenocarcinomaCOSMIC cancer mutationsstomach-carcinoma-intestinal_adenocarcinoma7225301682846 MLKL,ARAP3,RBM47,RXRA,ELF4,BLNK,CD53,ARHGEF1,MYO1F,PLEK,FLRT2,ABCA1,BAZ2B,GLDC,FNIP1,RHBDF1,FMNL1,DOCK4,AOX1,SH3KBP1,DAB2,ABCC5,MICAL2,STAB1,ARAP1,MARK4,SGMS1,ATP8A1,FERMT3,ETV6
1.893e-03-6.27intestinal_adenocarcinomaCOSMIC cancer mutationsintestinal_adenocarcinoma7225301682846 SGMS1,STAB1,ARAP1,MARK4,ETV6,FERMT3,ATP8A1,AOX1,FMNL1,DOCK4,ABCC5,MICAL2,DAB2,SH3KBP1,BAZ2B,ABCA1,PLEK,FLRT2,RHBDF1,GLDC,FNIP1,RXRA,ELF4,RBM47,ARAP3,MLKL,MYO1F,ARHGEF1,BLNK,CD53
1.923e-03-6.25organelle membranecellular componentGO:00310903742191910850 ARAP1,SGMS1,SH3KBP1,CD53,ABCA1,CD68,ATP8A1,MFSD1,FLRT2,CSF3R,FNIP1,STAB1,ADGRG3,ABCC5,MAN1A1,CERT1,RHBDF1,DAB2,TFEB
1.927e-03-6.25cellular response to xenobiotic stimulusbiological processGO:007146619341820450 ABCA1,AOX1,MEF2C,ABCC5
1.943e-03-6.24positive regulation of cellular processbiological processGO:00485225719261820450 ETV6,CEBPB,CD53,RXRA,ETS1,FLRT2,DISC1,DAB2,ELF4,CTSV,PLEK,MICAL2,ABCA1,SH3KBP1,HCK,FNIP1,BLNK,MARK4,RBM47,FERMT3,CD276,DOCK4,TFEB,ARAP1,MEF2C,ATP8A1
1.950e-03-6.24RhoGAPsmart domainsSM00324643971738 ARAP1,ARHGAP45,ARAP3
1.959e-03-6.24Regulation of signaling by CBLREACTOME pathwaysR-HSA-9126311821028538 BLNK,HCK
1.964e-03-6.23SAMinterpro domainsIPR0016609231852150 ARAP1,SGMS1,ARAP3
2.059e-03-6.19F_BARinterpro domainsIPR0311602521852150 ARHGAP45,FCHO2
2.133e-03-6.15endocytic vesiclecellular componentGO:003013934951910850 CSF3R,FMNL1,ABCA1,STAB1,SH3KBP1
2.146e-03-6.14response to lipopolysaccharidebiological processGO:003249633351820450 CD68,CEBPB,MEF2C,HCK,ABCA1
2.237e-03-6.10nucleoside-triphosphatase regulator activitymolecular functionGO:006058949161809450 RGL1,ARHGAP45,DOCK4,ARAP3,ARAP1,ARHGEF1
2.237e-03-6.10GTPase regulator activitymolecular functionGO:003069549161809450 ARAP3,ARHGAP45,RGL1,DOCK4,ARHGEF1,ARAP1
2.243e-03-6.10response to lipidbiological processGO:003399386281820450 RXRA,CD68,GLDC,MEF2C,ABCA1,DAB2,HCK,CEBPB
2.368e-03-6.05ATPase-coupled transmembrane transporter activitymolecular functionGO:00426269631809450 ABCC5,ATP8A1,ABCA1
2.401e-03-6.03ArfGAP_dominterpro domainsIPR0011642721852150 ARAP1,ARAP3
2.401e-03-6.03ArfGAP_dom_sfinterpro domainsIPR0385082721852150 ARAP1,ARAP3
2.401e-03-6.03ARFGAP/RecOinterpro domainsIPR0372782721852150 ARAP1,ARAP3
2.409e-03-6.03Transcription factor regulation in adipogenesisWikiPathwaysWP3599222531018 RXRA,CEBPB
2.450e-03-6.01response to bacteriumbiological processGO:000961768171820450 ABCA1,STAB1,TFEB,CEBPB,HCK,CD68,MEF2C
2.479e-03-6.00central_nervous_system-medulla-primitive_neuroectodermal_tumour-medulloblastoma-classicCOSMIC cancer mutationscentral_nervous_system-medulla-primitive_neuroectodermal_tumour-medulloblastoma-classic14773461682846 SH3KBP1,RGL1,FMNL1,CEBPB,CSF3R,TFEB,CD68,SRGN,MFSD1,FERMT3,ARAP1,BLNK,ARHGEF1,MYO1F,MLKL,SH2B3,FNIP1,DISC1,FCHO2,RHBDF1,DIAPH2,DAB2,ABCC5,MICAL2,DOCK4,ETS1,AOX1,CD276,ATP8A1,ETV6,STAB1,MAN1A1,MARK4,SGMS1,CD53,ARAP3,RBM47,RXRA,ELF4,MEF2C,GLDC,FLRT2,PLEK,HCK,ABCA1,BAZ2B
2.479e-03-6.00central_nervous_system-medulla-primitive_neuroectodermal_tumour-medulloblastoma-large_cellCOSMIC cancer mutationscentral_nervous_system-medulla-primitive_neuroectodermal_tumour-medulloblastoma-large_cell14773461682846 ABCC5,MICAL2,DIAPH2,DAB2,AOX1,DOCK4,ETS1,ETV6,ATP8A1,CD276,SGMS1,STAB1,MAN1A1,MARK4,CD53,RXRA,ELF4,RBM47,ARAP3,MEF2C,GLDC,BAZ2B,ABCA1,PLEK,FLRT2,HCK,RGL1,SH3KBP1,CD68,SRGN,TFEB,FMNL1,CEBPB,CSF3R,FERMT3,MFSD1,ARAP1,MYO1F,ARHGEF1,BLNK,SH2B3,MLKL,RHBDF1,DISC1,FCHO2,FNIP1
2.479e-03-6.00central_nervous_system-medulla-primitive_neuroectodermal_tumour-medulloblastomaCOSMIC cancer mutationscentral_nervous_system-medulla-primitive_neuroectodermal_tumour-medulloblastoma14773461682846 CD276,ATP8A1,ETV6,MARK4,MAN1A1,STAB1,SGMS1,DIAPH2,DAB2,MICAL2,ABCC5,ETS1,DOCK4,AOX1,GLDC,MEF2C,HCK,FLRT2,PLEK,ABCA1,BAZ2B,CD53,ARAP3,RBM47,ELF4,RXRA,MFSD1,FERMT3,ARAP1,SH3KBP1,RGL1,CEBPB,CSF3R,FMNL1,TFEB,SRGN,CD68,FNIP1,FCHO2,DISC1,RHBDF1,BLNK,ARHGEF1,MYO1F,MLKL,SH2B3
2.479e-03-6.00central_nervous_system-medulla-primitive_neuroectodermal_tumour-medulloblastoma-desmoplasticCOSMIC cancer mutationscentral_nervous_system-medulla-primitive_neuroectodermal_tumour-medulloblastoma-desmoplastic14773461682846 CD53,ARAP3,RXRA,ELF4,RBM47,MEF2C,GLDC,ABCA1,FLRT2,PLEK,HCK,BAZ2B,ABCC5,MICAL2,DIAPH2,DAB2,DOCK4,ETS1,AOX1,ATP8A1,CD276,ETV6,SGMS1,STAB1,MAN1A1,MARK4,ARHGEF1,BLNK,MYO1F,MLKL,SH2B3,DISC1,FCHO2,FNIP1,RHBDF1,SH3KBP1,RGL1,FMNL1,CSF3R,CEBPB,CD68,SRGN,TFEB,MFSD1,FERMT3,ARAP1
2.484e-03-6.00positive regulation of leukocyte apoptotic processbiological processGO:20001082721820450 FNIP1,MEF2C
2.484e-03-6.00positive regulation of cholesterol effluxbiological processGO:00108752721820450 ABCA1,RXRA
2.487e-03-6.00classicCOSMIC cancer mutationsclassic14774461682846 GLDC,MEF2C,ABCA1,PLEK,FLRT2,HCK,BAZ2B,CD53,ARAP3,RXRA,ELF4,RBM47,ATP8A1,CD276,ETV6,SGMS1,STAB1,MAN1A1,MARK4,ABCC5,MICAL2,DIAPH2,DAB2,DOCK4,ETS1,AOX1,DISC1,FCHO2,FNIP1,RHBDF1,ARHGEF1,BLNK,MYO1F,MLKL,SH2B3,MFSD1,FERMT3,ARAP1,SH3KBP1,RGL1,FMNL1,CSF3R,CEBPB,CD68,SRGN,TFEB
2.495e-03-5.99ArfGappfam domainsPF014122721779549 ARAP1,ARAP3
2.503e-03-5.99WH_DNA-bd_sfinterpro domainsIPR03639021141852150 PLEK,ETV6,ELF4,ETS1
2.513e-03-5.99ATPase-coupled intramembrane lipid transporter activitymolecular functionGO:01403262721809450 ATP8A1,ABCA1
2.518e-03-5.98medullaCOSMIC cancer mutationsmedulla14778461682846 GLDC,MEF2C,PLEK,FLRT2,HCK,ABCA1,BAZ2B,CD53,ARAP3,RBM47,RXRA,ELF4,CD276,ATP8A1,ETV6,STAB1,MARK4,MAN1A1,SGMS1,DAB2,DIAPH2,ABCC5,MICAL2,DOCK4,ETS1,AOX1,FNIP1,DISC1,FCHO2,RHBDF1,BLNK,ARHGEF1,MYO1F,MLKL,SH2B3,MFSD1,FERMT3,ARAP1,SH3KBP1,RGL1,FMNL1,CSF3R,CEBPB,TFEB,CD68,SRGN
2.526e-03-5.98desmoplasticCOSMIC cancer mutationsdesmoplastic14779461682846 FMNL1,CEBPB,CSF3R,CD68,SRGN,TFEB,SH3KBP1,RGL1,ARAP1,MFSD1,FERMT3,MLKL,SH2B3,ARHGEF1,BLNK,MYO1F,DISC1,FCHO2,FNIP1,RHBDF1,DOCK4,ETS1,AOX1,ABCC5,MICAL2,DIAPH2,DAB2,SGMS1,STAB1,MARK4,MAN1A1,ATP8A1,CD276,ETV6,ARAP3,RXRA,ELF4,RBM47,CD53,ABCA1,PLEK,FLRT2,HCK,BAZ2B,MEF2C,GLDC
2.529e-03-5.98cellular response to lipopolysaccharidebiological processGO:007122220841820450 ABCA1,MEF2C,HCK,CD68
2.541e-03-5.98phospholipid transportbiological processGO:00159149931820450 ATP8A1,CERT1,ABCA1
2.546e-03-5.97SH3-like_dom_sfinterpro domainsIPR03602821241852150 DOCK4,MYO1F,HCK,SH3KBP1
2.570e-03-5.96Irf2bp1 (interferon regulatory factor 2 binding protein 1)protein interactions272359111945450 SH3KBP1
2.570e-03-5.96Blnk (B cell linker)protein interactions17060111945450 SH3KBP1
2.570e-03-5.96CBP (sarcoplasmic calcium-binding protein)protein interactions31669111945450 SH3KBP1
2.570e-03-5.96Parp1 (poly (ADP-ribose) polymerase 1)protein interactions25591111945450 RXRA
2.570e-03-5.96Arap1 (ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1)protein interactions69710111945450 SH3KBP1
2.570e-03-5.96Pik3cd (phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta)protein interactions18707111945450 SH3KBP1
2.570e-03-5.96Rtkn2 (rhotekin 2)protein interactions170799111945450 SH3KBP1
2.570e-03-5.96Chtf8 (CTF8, chromosome transmission fidelity factor 8)protein interactions214987111945450 SH3KBP1
2.570e-03-5.96Wipf1 (WAS/WASL interacting protein family, member 1)protein interactions215280111945450 SH3KBP1
2.570e-03-5.96Pdcd6ip (programmed cell death 6 interacting protein)protein interactions18571111945450 SH3KBP1
2.570e-03-5.96Pik3ap1 (phosphoinositide-3-kinase adaptor protein 1)protein interactions83490111945450 SH3KBP1
2.570e-03-5.96pparg.L (peroxisome proliferator activated receptor gamma L homeolog)protein interactions397769111945450 RXRA
2.570e-03-5.96Gtse1 (G two S phase expressed protein 1)protein interactions29870111945450 SH3KBP1
2.570e-03-5.96Was (Wiskott-Aldrich syndrome)protein interactions22376111945450 SH3KBP1
2.570e-03-5.96Sh3bp1 (SH3-domain binding protein 1)protein interactions20401111945450 SH3KBP1
2.570e-03-5.96Map4k1 (mitogen-activated protein kinase kinase kinase kinase 1)protein interactions26411111945450 SH3KBP1
2.570e-03-5.96Inpp5d (inositol polyphosphate-5-phosphatase D)protein interactions16331111945450 SH3KBP1
2.570e-03-5.96LINC00473 (long intergenic non-protein coding RNA 473)protein interactions90632111945450 CEBPB
2.570e-03-5.96Impdh1 (inosine monophosphate dehydrogenase 1)protein interactions23917111945450 SH3KBP1
2.570e-03-5.96Hectd1 (HECT domain E3 ubiquitin protein ligase 1)protein interactions100762999111945450 ABCA1
2.570e-03-5.96Stap1 (signal transducing adaptor family member 1)protein interactions56792111945450 SH3KBP1
2.570e-03-5.96Shkbp1 (Sh3kbp1 binding protein 1)protein interactions192192111945450 SH3KBP1
2.570e-03-5.96Tfap2a (transcription factor AP-2 alpha)protein interactions306862111945450 DAB2
2.573e-03-5.96import into cellbiological processGO:009865768771820450 STAB1,DAB2,FCHO2,MYO1F,HCK,SH3KBP1,ABCA1
2.614e-03-5.95hematopoietic progenitor cell differentiationbiological processGO:000224410031820450 RBM47,PLEK,SH2B3
2.628e-03-5.94APLP2 (amyloid beta precursor like protein 2)protein interactions33410731945450 DAB2,DISC1,ETS1
2.630e-03-5.94SH2pfam domainsPF0001710031779549 HCK,BLNK,SH2B3
2.639e-03-5.94SAM_DOMAINprosite domainsPS501057531218645 ARAP1,ARAP3,SGMS1
2.670e-03-5.93positive regulation of phosphatase activitybiological processGO:00109222821820450 PLEK,MEF2C
2.690e-03-5.92CSF3R (colony stimulating factor 3 receptor)protein interactions14413021945450 CSF3R,HCK
2.697e-03-5.92liver-carcinoma-hepatocellular_carcinomaCOSMIC cancer mutationsliver-carcinoma-hepatocellular_carcinoma14800461682846 MEF2C,GLDC,FNIP1,DISC1,FCHO2,RHBDF1,PLEK,FLRT2,HCK,ABCA1,BAZ2B,BLNK,CD53,ARHGEF1,MYO1F,MLKL,ARAP3,SH2B3,RBM47,RXRA,ELF4,MFSD1,CD276,ATP8A1,FERMT3,ETV6,ARAP1,STAB1,MARK4,MAN1A1,SGMS1,SH3KBP1,RGL1,DAB2,DIAPH2,ABCC5,MICAL2,FMNL1,DOCK4,ETS1,CEBPB,CSF3R,TFEB,AOX1,CD68,SRGN
2.697e-03-5.92hepatocellular_carcinomaCOSMIC cancer mutationshepatocellular_carcinoma14800461682846 SH3KBP1,RGL1,CEBPB,CSF3R,FMNL1,TFEB,SRGN,CD68,MFSD1,FERMT3,ARAP1,BLNK,ARHGEF1,MYO1F,MLKL,SH2B3,FNIP1,FCHO2,DISC1,RHBDF1,DAB2,DIAPH2,MICAL2,ABCC5,ETS1,DOCK4,AOX1,CD276,ATP8A1,ETV6,MAN1A1,MARK4,STAB1,SGMS1,CD53,ARAP3,RBM47,ELF4,RXRA,MEF2C,GLDC,HCK,PLEK,FLRT2,ABCA1,BAZ2B
2.700e-03-5.91CIN85_SH3_1interpro domainsIPR035770111852150 SH3KBP1
2.700e-03-5.91GDC-P_Cinterpro domainsIPR049316111852150 GLDC
2.700e-03-5.91Serglycininterpro domainsIPR007455111852150 SRGN
2.700e-03-5.91SAM_PNT-ETS-1interpro domainsIPR041886111852150 ETS1
2.700e-03-5.91GDC-P_Ninterpro domainsIPR049315111852150 GLDC
2.700e-03-5.91CD276_IgVinterpro domainsIPR047318111852150 CD276
2.700e-03-5.91ProQ/FinOinterpro domainsIPR016103111852150 MICAL2
2.700e-03-5.91RBM47_RRM1interpro domainsIPR047044111852150 RBM47
2.700e-03-5.91p115RhoGEF_RGSinterpro domainsIPR037887111852150 ARHGEF1
2.700e-03-5.91ArAA_b-elim_lyase/Thr_aldolaseinterpro domainsIPR001597111852150 GLDC
2.700e-03-5.91CIN85_SH3_3interpro domainsIPR035772111852150 SH3KBP1
2.700e-03-5.91CIN85_SH3_2interpro domainsIPR035771111852150 SH3KBP1
2.700e-03-5.91RBM47_RRM2interpro domainsIPR034440111852150 RBM47
2.700e-03-5.91GDC_Pinterpro domainsIPR020581111852150 GLDC
2.700e-03-5.91DISC1interpro domainsIPR026081111852150 DISC1
2.700e-03-5.91HCK_SH2interpro domainsIPR035851111852150 HCK
2.700e-03-5.91RGL1_RAinterpro domainsIPR030748111852150 RGL1
2.700e-03-5.91DOCK4_SH3interpro domainsIPR035769111852150 DOCK4
2.700e-03-5.91DHR2_DOCK4interpro domainsIPR037014111852150 DOCK4
2.700e-03-5.91Aldehyde_oxidaseinterpro domainsIPR014313111852150 AOX1
2.700e-03-5.91PLEK_DEPinterpro domainsIPR037371111852150 PLEK
2.700e-03-5.91FCHo2_F-BARinterpro domainsIPR030122111852150 FCHO2
2.700e-03-5.91RBM47_RRM3interpro domainsIPR034445111852150 RBM47
2.700e-03-5.91GcvPinterpro domainsIPR003437111852150 GLDC
2.700e-03-5.91bHLHzip_TFEBinterpro domainsIPR024098111852150 TFEB
2.700e-03-5.91SH2B3_SH2interpro domainsIPR035059111852150 SH2B3
2.700e-03-5.91STARD11_STARTinterpro domainsIPR041952111852150 CERT1
2.747e-03-5.90protease localization to T cell secretory granulebiological processGO:0033375111820450 SRGN
2.747e-03-5.90sinoatrial valve morphogenesisbiological processGO:0003185111820450 MEF2C
2.747e-03-5.90intermembrane sphingolipid transferbiological processGO:0120012111820450 CERT1
2.747e-03-5.90regulation of cell diameterbiological processGO:0060305111820450 PLEK
2.747e-03-5.90protein localization to mast cell secretory granulebiological processGO:0033367111820450 SRGN
2.747e-03-5.90maintenance of protease location in mast cell secretory granulebiological processGO:0033373111820450 SRGN
2.747e-03-5.90protein secretion by plateletbiological processGO:0070560111820450 PLEK
2.747e-03-5.90regulation of inositol-polyphosphate 5-phosphatase activitybiological processGO:0010924111820450 PLEK
2.747e-03-5.90cGMP transportbiological processGO:0070731111820450 ABCC5
2.747e-03-5.90protease localization to mast cell secretory granulebiological processGO:0033368111820450 SRGN
2.747e-03-5.90leading edge cell differentiationbiological processGO:0035026111820450 DAB2
2.747e-03-5.90granzyme B localization to T cell secretory granulebiological processGO:0033380111820450 SRGN
2.747e-03-5.90maintenance of granzyme B location in T cell secretory granulebiological processGO:0033382111820450 SRGN
2.747e-03-5.90protein localization to T cell secretory granulebiological processGO:0033374111820450 SRGN
2.747e-03-5.90response to lipoic acidbiological processGO:1903442111820450 GLDC
2.747e-03-5.90phospholipase C-inhibiting G protein-coupled receptor signaling pathwaybiological processGO:0030845111820450 PLEK
2.747e-03-5.90T cell secretory granule organizationbiological processGO:0033371111820450 SRGN
2.747e-03-5.90maintenance of protease location in T cell secretory granulebiological processGO:0033379111820450 SRGN
2.747e-03-5.90response to methylaminebiological processGO:0036255111820450 GLDC
2.747e-03-5.90maintenance of protein location in mast cell secretory granulebiological processGO:0033370111820450 SRGN
2.747e-03-5.90positive regulation of inositol-polyphosphate 5-phosphatase activitybiological processGO:0010925111820450 PLEK
2.747e-03-5.90maintenance of protein location in T cell secretory granulebiological processGO:0033377111820450 SRGN
2.754e-03-5.89GcvP2_Cpfam domainsPF21478111779549 GLDC
2.754e-03-5.89GDC-Ppfam domainsPF02347111779549 GLDC
2.754e-03-5.89Serglycinpfam domainsPF04360111779549 SRGN
2.754e-03-5.89Beta_elim_lyasepfam domainsPF01212111779549 GLDC
2.763e-03-5.89glycine dehydrogenase (decarboxylating) activitymolecular functionGO:0004375111809450 GLDC
2.763e-03-5.89granulocyte colony-stimulating factor bindingmolecular functionGO:0051916111809450 CSF3R
2.763e-03-5.89pyridoxal bindingmolecular functionGO:0070280111809450 GLDC
2.763e-03-5.89oxidoreductase activity, acting on the CH-NH2 group of donors, disulfide as acceptormolecular functionGO:0016642111809450 GLDC
2.777e-03-5.89cell motilitybiological processGO:0048870110191820450 DISC1,SH3KBP1,FMNL1,DOCK4,CSF3R,HCK,RHBDF1,ETS1,MEF2C
2.795e-03-5.88response to molecule of bacterial originbiological processGO:000223735451820450 ABCA1,HCK,CEBPB,MEF2C,CD68
2.812e-03-5.87regulation of anatomical structure morphogenesisbiological processGO:002260389481820450 ETS1,MEF2C,DISC1,SH3KBP1,FMNL1,STAB1,ARAP1,HCK
2.870e-03-5.85regulation of signal transductionbiological processGO:00099663114171820450 ADGRG3,SGMS1,DISC1,ARAP1,DAB2,RHBDF1,ARHGEF1,MEF2C,CTSV,PLEK,ABCA1,ARHGAP45,FNIP1,SH2B3,RXRA,MARK4,RBM47
2.870e-03-5.85PSRC1 (proline and serine rich coiled-coil 1)protein interactions847223121945450 SRGN,SH3KBP1
2.897e-03-5.84regulation of myeloid cell differentiationbiological processGO:004563721641820450 CSF3R,CEBPB,ETS1,MEF2C
2.897e-03-5.84phosphatidylinositol-3,4-bisphosphate bindingmolecular functionGO:00433252921809450 ARAP3,PLEK
2.939e-03-5.83ETS_DOMAIN_1prosite domainsPS003452221218645 ETS1,ELF4
2.991e-03-5.81GGA3 (golgi associated, gamma adaptin ear containing, ARF binding protein 3)protein interactions2316311231945450 ETS1,STAB1,ARAP3
3.003e-03-5.81Golgi apparatuscellular componentGO:00057941645111910850 ATP8A1,CERT1,MAN1A1,ABCC5,DOCK4,ABCA1,HCK,SGMS1,ARAP1,SRGN,RHBDF1
3.005e-03-5.81SH3_domaininterpro domainsIPR00145222241852150 DOCK4,MYO1F,HCK,SH3KBP1
3.102e-03-5.78large_cellCOSMIC cancer mutationslarge_cell14845461682846 SGMS1,MARK4,MAN1A1,STAB1,ARAP1,ATP8A1,MFSD1,CD276,ETV6,FERMT3,CSF3R,ETS1,CEBPB,DOCK4,FMNL1,SRGN,CD68,AOX1,TFEB,SH3KBP1,MICAL2,ABCC5,DAB2,DIAPH2,RGL1,ABCA1,HCK,FLRT2,PLEK,BAZ2B,FCHO2,DISC1,FNIP1,GLDC,MEF2C,RHBDF1,ARAP3,MLKL,ELF4,RXRA,RBM47,SH2B3,ARHGEF1,CD53,BLNK,MYO1F
3.145e-03-5.76cellular response to molecule of bacterial originbiological processGO:007121922141820450 ABCA1,CD68,MEF2C,HCK
3.159e-03-5.76Regulation of RhoA activityPathway Interaction DBrhoa_reg_pathway463222615 ARHGEF1,ARAP3,ARAP1
3.179e-03-5.75SH2interpro domainsIPR00098010931852150 HCK,SH2B3,BLNK
3.222e-03-5.74PPARD (peroxisome proliferator activated receptor delta)protein interactions546711531945450 ARAP3,RXRA,ARHGEF1
3.249e-03-5.73RARB (retinoic acid receptor beta)protein interactions59153321945450 RXRA,CEBPB
3.261e-03-5.73regulation of immune system processbiological processGO:00026821584111820450 MEF2C,CD68,CD276,MARK4,ETS1,RBM47,BLNK,HCK,CEBPB,CSF3R,SH3KBP1
3.274e-03-5.72FCHsmart domainsSM00055222971738 ARHGAP45,FCHO2
3.279e-03-5.72RHOD (ras homolog family member D)protein interactions2998457061945450 FMNL1,FCHO2,DAB2,DIAPH2,ABCC5,FLRT2
3.301e-03-5.71right_lower_lobeCOSMIC cancer mutationsright_lower_lobe5692251682846 MYO1F,ARAP3,RHBDF1,DISC1,FCHO2,GLDC,FNIP1,BAZ2B,ABCA1,PLEK,FLRT2,MICAL2,RGL1,DIAPH2,DAB2,SH3KBP1,AOX1,TFEB,FMNL1,DOCK4,ETV6,FERMT3,MFSD1,CD276,MARK4
3.301e-03-5.71lung-right_lower_lobe-carcinoma-adenocarcinomaCOSMIC cancer mutationslung-right_lower_lobe-carcinoma-adenocarcinoma5692251682846 MICAL2,RGL1,DIAPH2,DAB2,SH3KBP1,AOX1,TFEB,DOCK4,FMNL1,ETV6,FERMT3,CD276,MFSD1,MARK4,MYO1F,ARAP3,RHBDF1,DISC1,FCHO2,GLDC,FNIP1,BAZ2B,ABCA1,PLEK,FLRT2
3.306e-03-5.71lipoprotein particle bindingmolecular functionGO:00718133121809450 STAB1,ABCA1
3.306e-03-5.71protein-lipid complex bindingmolecular functionGO:00718143121809450 STAB1,ABCA1
3.375e-03-5.69cell migrationbiological processGO:001647792181820450 RHBDF1,MEF2C,FMNL1,DISC1,SH3KBP1,HCK,CSF3R,DOCK4
3.387e-03-5.69urinary_tract-bladder-carcinoma-transitional_cell_carcinomaCOSMIC cancer mutationsurinary_tract-bladder-carcinoma-transitional_cell_carcinoma6040261682846 BLNK,ARHGEF1,MYO1F,ARAP3,RBM47,RXRA,ELF4,GLDC,FLRT2,HCK,ABCA1,BAZ2B,SH3KBP1,DAB2,DIAPH2,ABCC5,FMNL1,CSF3R,AOX1,CD276,ATP8A1,FERMT3,STAB1,ARAP1,MARK4,SGMS1
3.405e-03-5.68transitional_cell_carcinomaCOSMIC cancer mutationstransitional_cell_carcinoma6042261682846 SH3KBP1,ABCC5,DAB2,DIAPH2,CSF3R,FMNL1,AOX1,ATP8A1,CD276,FERMT3,SGMS1,MARK4,ARAP1,STAB1,ARHGEF1,BLNK,MYO1F,ARAP3,ELF4,RXRA,RBM47,GLDC,ABCA1,HCK,FLRT2,BAZ2B
3.426e-03-5.68skin-trunk-malignant_melanomaCOSMIC cancer mutationsskin-trunk-malignant_melanoma2647151682846 STAB1,MAN1A1,FLRT2,HCK,ABCA1,GLDC,ATP8A1,AOX1,SRGN,FMNL1,MYO1F,DAB2,ABCC5,MICAL2,SH3KBP1
3.442e-03-5.67Arf GTPase activating proteingene3d domains1.10.220.1502721447047 ARAP3,ARAP1
3.446e-03-5.67ELMO1 (engulfment and cell motility 1)protein interactions98443421945450 DOCK4,HCK
3.498e-03-5.66cell population proliferationbiological processGO:000828372671820450 MEF2C,CERT1,RHBDF1,ELF4,CEBPB,ETV6,DISC1
3.516e-03-5.65immune response-activating cell surface receptor signaling pathwaybiological processGO:000242922841820450 CD276,BLNK,HCK,MEF2C
3.519e-03-5.65SH2_dom_sfinterpro domainsIPR03686011331852150 BLNK,SH2B3,HCK
3.519e-03-5.65WH-like_DNA-bd_sfinterpro domainsIPR03638823241852150 ETS1,ELF4,ETV6,PLEK
3.520e-03-5.65macromolecule transmembrane transporter activitymolecular functionGO:00228843221809450 ABCA1,ABCC5
3.538e-03-5.64myelodysplastic-myeloproliferative_neoplasm-unclassifiableCOSMIC cancer mutationsmyelodysplastic-myeloproliferative_neoplasm-unclassifiable11231682846 SH2B3,ETV6,CSF3R
3.538e-03-5.64haematopoietic_and_lymphoid_tissue-haematopoietic_neoplasm-myelodysplastic-myeloproliferative_neoplasm-unclassifiableCOSMIC cancer mutationshaematopoietic_and_lymphoid_tissue-haematopoietic_neoplasm-myelodysplastic-myeloproliferative_neoplasm-unclassifiable11231682846 CSF3R,ETV6,SH2B3
3.629e-03-5.62TOP3B (DNA topoisomerase III beta)protein interactions89401465101945450 SH2B3,RBM47,RHBDF1,ARAP3,TFEB,MARK4,CEBPB,ARAP1,DIAPH2,CD276
3.668e-03-5.61CAPZA2 (capping actin protein of muscle Z-line subunit alpha 2)protein interactions83040351945450 ARAP1,BLNK,FCHO2,DAB2,SH3KBP1
3.682e-03-5.60RXR and RAR heterodimerization with other nuclear receptorPathway Interaction DBrxr_vdr_pathway142222615 RXRA,ABCA1
3.751e-03-5.59cellular component organizationbiological processGO:00160435636251820450 TFEB,ARAP1,FCHO2,SRGN,FERMT3,FMNL1,MYO1F,ATP8A1,HCK,ARAP3,ABCA1,SH3KBP1,CERT1,MARK4,DAB2,FLRT2,DISC1,CTSV,MICAL2,BAZ2B,PLEK,DIAPH2,ETV6,ETS1,MLKL
3.767e-03-5.58haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-acute_lymphoblastic_B_cell_leukaemiaCOSMIC cancer mutationshaematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-acute_lymphoblastic_B_cell_leukaemia3828191682846 ETV6,ATP8A1,MEF2C,GLDC,MAN1A1,ARAP1,STAB1,ABCA1,FLRT2,MICAL2,ABCC5,DAB2,DIAPH2,SH3KBP1,BLNK,SH2B3,CSF3R,FMNL1,MLKL
3.767e-03-5.58acute_lymphoblastic_B_cell_leukaemiaCOSMIC cancer mutationsacute_lymphoblastic_B_cell_leukaemia3828191682846 MAN1A1,ARAP1,STAB1,ABCA1,FLRT2,ETV6,ATP8A1,GLDC,MEF2C,SH2B3,CSF3R,FMNL1,MLKL,MICAL2,ABCC5,DIAPH2,DAB2,SH3KBP1,BLNK
3.790e-03-5.58F_BARprosite domainsPS517412521218645 FCHO2,ARHGAP45
3.819e-03-5.57actin filamentcellular componentGO:000588412031910850 HCK,DIAPH2,MICAL2
3.825e-03-5.57SMARCA4 (SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4)protein interactions659740751945450 CEBPB,ETS1,MARK4,RXRA,GLDC
3.836e-03-5.56RAC1 (Rac family small GTPase 1)protein interactions5879100581945450 DIAPH2,ARAP1,DOCK4,FLRT2,FMNL1,DAB2,FCHO2,ABCC5
3.905e-03-5.55LIMA1 (LIM domain and actin binding 1)protein interactions5147440951945450 FCHO2,DAB2,DISC1,FMNL1,GLDC
3.911e-03-5.54ProQsmart domainsSM0094511971738 MICAL2
4.068e-03-5.50B Cell Receptor Signaling PathwayWikiPathwaysWP23983531018 BLNK,ETS1,MEF2C
4.077e-03-5.50intracellular organellecellular componentGO:004322913594441910850 MYO1F,CD68,RXRA,ETS1,CSF3R,MARK4,MICAL2,ARHGAP45,FLRT2,ADGRG3,DOCK4,STAB1,MEF2C,FNIP1,RBM47,FMNL1,DAB2,GLDC,BLNK,TFEB,DISC1,FERMT3,ABCA1,HCK,CD53,ARAP1,SH3KBP1,SGMS1,MFSD1,ETV6,ATP8A1,DIAPH2,CEBPB,CTSV,BAZ2B,ARAP3,ABCC5,MAN1A1,ELF4,FCHO2,CERT1,RHBDF1,SRGN,MLKL
4.079e-03-5.50regulation of biological qualitybiological processGO:00650082936161820450 HCK,ABCA1,SH3KBP1,RBM47,SH2B3,ARAP1,DAB2,DOCK4,FERMT3,FMNL1,FLRT2,MFSD1,DISC1,MEF2C,ATP8A1,PLEK
4.152e-03-5.48response to fluid shear stressbiological processGO:00344053521820450 ABCA1,MEF2C
4.155e-03-5.48biological regulationbiological processGO:006500712501431820450 SGMS1,FLRT2,DISC1,DAB2,ELF4,CTSV,BAZ2B,PLEK,MICAL2,ETV6,CEBPB,ARHGAP45,CD53,MLKL,RXRA,ETS1,RGL1,ADGRG3,FMNL1,SRGN,FERMT3,MFSD1,CD276,DOCK4,ARAP1,TFEB,RHBDF1,MEF2C,ARHGEF1,ATP8A1,CD68,ABCA1,SH3KBP1,HCK,ARAP3,CSF3R,STAB1,FNIP1,SH2B3,BLNK,MARK4,CERT1,RBM47
4.175e-03-5.48response to external stimulusbiological processGO:00096051882121820450 MLKL,ABCA1,CEBPB,HCK,STAB1,CSF3R,MEF2C,CD68,FLRT2,DISC1,TFEB,DOCK4
4.200e-03-5.47nef (Nef)protein interactions15611080271945450 CD53,RXRA,SH3KBP1,DAB2,TFEB,HCK,ABCA1
4.209e-03-5.47cytoplasmic vesicle membranecellular componentGO:0030659123091910850 CSF3R,DAB2,CD68,ATP8A1,CD53,SH3KBP1,ADGRG3,ABCC5,STAB1
4.228e-03-5.47essential_thrombocythaemiaCOSMIC cancer mutationsessential_thrombocythaemia39351682846 FLRT2,CSF3R,STAB1,SH2B3,RHBDF1
4.228e-03-5.47haematopoietic_and_lymphoid_tissue-haematopoietic_neoplasm-essential_thrombocythaemiaCOSMIC cancer mutationshaematopoietic_and_lymphoid_tissue-haematopoietic_neoplasm-essential_thrombocythaemia39351682846 RHBDF1,SH2B3,STAB1,CSF3R,FLRT2
4.233e-03-5.46large_intestine-caecum-carcinoma-adenocarcinomaCOSMIC cancer mutationslarge_intestine-caecum-carcinoma-adenocarcinoma14236451682846 FNIP1,FCHO2,DISC1,RHBDF1,MLKL,SH2B3,ARHGEF1,MYO1F,ARAP1,MFSD1,FERMT3,CEBPB,CSF3R,FMNL1,TFEB,SRGN,CD68,SH3KBP1,RGL1,HCK,FLRT2,PLEK,ABCA1,BAZ2B,MEF2C,GLDC,ARAP3,RBM47,ELF4,RXRA,CD53,MAN1A1,MARK4,STAB1,SGMS1,CD276,ATP8A1,ETV6,ETS1,DOCK4,AOX1,DIAPH2,DAB2,MICAL2,ABCC5
4.290e-03-5.45BHLHE41 (basic helix-loop-helix family member e41)protein interactions793653821945450 RXRA,CEBPB
4.290e-03-5.45NT5C (5', 3'-nucleotidase, cytosolic)protein interactions308333821945450 ARHGEF1,ARAP3
4.314e-03-5.45PLCG1 (phospholipase C gamma 1)protein interactions533525841945450 SH2B3,DISC1,BLNK,HCK
4.363e-03-5.43Signaling by Rho GTPasesREACTOME pathwaysR-HSA-19431542661028538 ARHGAP45,ARHGEF1,FMNL1,ARAP3,DIAPH2,ARAP1
4.378e-03-5.43regulation of biological processbiological processGO:005078912079421820450 DAB2,DISC1,SGMS1,FLRT2,BAZ2B,PLEK,MICAL2,CTSV,ELF4,ARHGAP45,ETV6,CEBPB,ETS1,RXRA,CD53,MLKL,DOCK4,TFEB,ARAP1,CD276,RGL1,ADGRG3,FERMT3,SRGN,FMNL1,ATP8A1,CD68,ARHGEF1,MEF2C,RHBDF1,CSF3R,ARAP3,STAB1,HCK,SH3KBP1,ABCA1,RBM47,CERT1,MARK4,BLNK,SH2B3,FNIP1
4.380e-03-5.43caecumCOSMIC cancer mutationscaecum14248451682846 ETS1,DOCK4,AOX1,DAB2,DIAPH2,MICAL2,ABCC5,MAN1A1,MARK4,STAB1,SGMS1,CD276,ATP8A1,ETV6,ARAP3,RBM47,ELF4,RXRA,CD53,HCK,FLRT2,PLEK,ABCA1,BAZ2B,GLDC,MEF2C,CSF3R,CEBPB,FMNL1,TFEB,SRGN,CD68,SH3KBP1,RGL1,ARAP1,MFSD1,FERMT3,MLKL,SH2B3,ARHGEF1,MYO1F,FNIP1,FCHO2,DISC1,RHBDF1
4.388e-03-5.43TOR signalingbiological processGO:00319293621820450 DISC1,FNIP1
4.388e-03-5.43positive regulation of cholesterol transportbiological processGO:00323763621820450 ABCA1,RXRA
4.388e-03-5.43positive regulation of sterol transportbiological processGO:00323733621820450 ABCA1,RXRA
4.413e-03-5.42ARFGAPprosite domainsPS501152721218645 ARAP3,ARAP1
4.542e-03-5.39femurCOSMIC cancer mutationsfemur119791682846 CSF3R,ABCA1,STAB1,BAZ2B,RBM47,ELF4,GLDC,BLNK,DAB2
4.577e-03-5.39lung-carcinoma-small_cell_carcinomaCOSMIC cancer mutationslung-carcinoma-small_cell_carcinoma9908361682846 TFEB,AOX1,FMNL1,DOCK4,CEBPB,ETS1,CSF3R,RGL1,DAB2,DIAPH2,MICAL2,SH3KBP1,ARAP1,STAB1,MARK4,MAN1A1,SGMS1,ETV6,CD276,MFSD1,RBM47,SH2B3,ELF4,MLKL,ARAP3,MYO1F,CD53,ARHGEF1,BAZ2B,FLRT2,HCK,ABCA1,GLDC,MEF2C,FNIP1,DISC1
4.605e-03-5.38regulation of cell morphogenesisbiological processGO:002260424641820450 ARAP1,HCK,SH3KBP1,FMNL1
4.631e-03-5.38small_cell_carcinomaCOSMIC cancer mutationssmall_cell_carcinoma9913361682846 DAB2,DIAPH2,RGL1,MICAL2,SH3KBP1,TFEB,AOX1,CSF3R,ETS1,CEBPB,FMNL1,DOCK4,ETV6,MFSD1,CD276,MARK4,MAN1A1,ARAP1,STAB1,SGMS1,MYO1F,CD53,ARHGEF1,SH2B3,RBM47,ELF4,MLKL,ARAP3,FNIP1,GLDC,MEF2C,DISC1,BAZ2B,HCK,FLRT2,ABCA1
4.631e-03-5.38cellular response to low-density lipoprotein particle stimulusbiological processGO:00714043721820450 ABCA1,CD68
4.631e-03-5.38response to lipoprotein particlebiological processGO:00550943721820450 ABCA1,CD68
4.672e-03-5.37cellular response to biotic stimulusbiological processGO:007121624741820450 CD68,MEF2C,HCK,ABCA1
4.684e-03-5.36STAT3 (signal transducer and activator of transcription 3)protein interactions677442751945450 HCK,SH3KBP1,CEBPB,RXRA,CSF3R
4.703e-03-5.36vesicle membranecellular componentGO:0012506125191910850 DAB2,CSF3R,STAB1,ABCC5,ADGRG3,SH3KBP1,CD53,ATP8A1,CD68
4.742e-03-5.35TXNDC12 (thioredoxin domain containing 12)protein interactions5106013231945450 ARHGEF1,HCK,DIAPH2
4.788e-03-5.34regulation of ossificationbiological processGO:003027812431820450 SRGN,RXRA,MEF2C
4.915e-03-5.32ArfGapsmart domainsSM00105272971738 ARAP1,ARAP3
4.979e-03-5.30protein tyrosine kinase bindingmolecular functionGO:199078212531809450 DOCK4,SH2B3,BLNK
4.980e-03-5.30RASSF7 (Ras association domain family member 7)protein interactions80454121945450 DISC1,CEBPB
4.994e-03-5.30pancreas-carcinoid-endocrine_tumourCOSMIC cancer mutationspancreas-carcinoid-endocrine_tumour7250291682846 SH3KBP1,ABCC5,MICAL2,RGL1,DIAPH2,FMNL1,CSF3R,AOX1,SRGN,ATP8A1,CD276,ETV6,SGMS1,STAB1,MAN1A1,MARK4,ARHGEF1,BLNK,MYO1F,MLKL,RXRA,ELF4,SH2B3,FCHO2,GLDC,FNIP1,ABCA1,PLEK,BAZ2B
5.094e-03-5.28SRC (SRC proto-oncogene, non-receptor tyrosine kinase)protein interactions671462461945450 ETS1,RXRA,CTSV,DAB2,HCK,SH3KBP1
5.127e-03-5.27RHOB (ras homolog family member B)protein interactions38883271945450 FLRT2,DIAPH2,ABCC5,ARHGEF1,DAB2,FCHO2,FMNL1
5.134e-03-5.27Atf2 (activating transcription factor 2)protein interactions81647211945450 CEBPB
5.134e-03-5.27Cbl (Cbl proto-oncogene)protein interactions500985211945450 SH3KBP1
5.134e-03-5.27Micall1 (microtubule associated monooxygenase, calponin and LIM domain containing -like 1)protein interactions27008211945450 SH3KBP1
5.134e-03-5.27Idh3b (isocitrate dehydrogenase 3 (NAD+) beta)protein interactions170718211945450 SH3KBP1
5.134e-03-5.27Ap2a1 (adaptor-related protein complex 2, alpha 1 subunit)protein interactions11771211945450 SH3KBP1
5.134e-03-5.27Flcn (folliculin)protein interactions303185211945450 FNIP1
5.134e-03-5.27Sh3kbp1 (SH3-domain kinase binding protein 1)protein interactions58194211945450 SH3KBP1
5.134e-03-5.27Gcdh (glutaryl-Coenzyme A dehydrogenase)protein interactions270076211945450 SH3KBP1
5.134e-03-5.27Timm50 (translocase of inner mitochondrial membrane 50)protein interactions66525211945450 SH3KBP1
5.134e-03-5.27Wasl (WASP like actin nucleation promoting factor)protein interactions73178211945450 SH3KBP1
5.134e-03-5.27Arhgap17 (Rho GTPase activating protein 17)protein interactions70497211945450 SH3KBP1
5.134e-03-5.27Dbt (dihydrolipoamide branched chain transacylase E2)protein interactions13171211945450 SH3KBP1
5.153e-03-5.27EMSY (EMSY transcriptional repressor, BRCA2 interacting)protein interactions5694613631945450 ETS1,ELF4,DISC1
5.227e-03-5.25C/EBP complexcellular componentGO:1990647211910850 CEBPB
5.227e-03-5.25glycine cleavage complexcellular componentGO:0005960211910850 GLDC
5.319e-03-5.24soft_tissue-striated_muscle-rhabdomyosarcomaCOSMIC cancer mutationssoft_tissue-striated_muscle-rhabdomyosarcoma59461682846 DOCK4,FNIP1,ABCC5,RGL1,DIAPH2,DAB2
5.346e-03-5.23kinase bindingmolecular functionGO:001990078071809450 MLKL,PLEK,CEBPB,DOCK4,MICAL2,SH2B3,BLNK
5.392e-03-5.22Ald_Oxase/xanthine_DH-likeinterpro domainsIPR016208211852150 AOX1
5.392e-03-5.22DAB1/2_SBMinterpro domainsIPR048559211852150 DAB2
5.392e-03-5.22FNIP_N_dominterpro domainsIPR028084211852150 FNIP1
5.392e-03-5.22Mopterin_DH_FAD-bdinterpro domainsIPR002346211852150 AOX1
5.392e-03-5.22Ald_Oxase/Xan_DH_a/b_sfinterpro domainsIPR036856211852150 AOX1
5.392e-03-5.22DENN_FNIP1/2interpro domainsIPR037545211852150 FNIP1
5.392e-03-5.222Fe-2S-bdinterpro domainsIPR002888211852150 AOX1
5.392e-03-5.22Nuc_recep-AF1interpro domainsIPR021780211852150 RXRA
5.392e-03-5.22Dab_PTBinterpro domainsIPR048561211852150 DAB2
5.392e-03-5.22Ie/If_SH3interpro domainsIPR035507211852150 MYO1F
5.392e-03-5.22Ets1_N_flankinterpro domainsIPR045688211852150 ETS1
5.392e-03-5.22Transform_prot_C-etsinterpro domainsIPR016311211852150 ETS1
5.392e-03-5.22FNIP_faminterpro domainsIPR026156211852150 FNIP1
5.392e-03-5.22BAZ2A/B_Bromointerpro domainsIPR037374211852150 BAZ2B
5.392e-03-5.22CO_DH_flav_Cinterpro domainsIPR005107211852150 AOX1
5.392e-03-5.22C2_Dock-Binterpro domainsIPR037811211852150 DOCK4
5.392e-03-5.22CO_DH_flav_C_dom_sfinterpro domainsIPR036683211852150 AOX1
5.392e-03-5.22FNIP_mid_dominterpro domainsIPR028085211852150 FNIP1
5.392e-03-5.22AldOxase/xan_DH_MoCoBD1interpro domainsIPR008274211852150 AOX1
5.392e-03-5.22Ald_Oxase/Xan_DH_a/binterpro domainsIPR000674211852150 AOX1
5.392e-03-5.22iRhom1_2_Ninterpro domainsIPR022241211852150 RHBDF1
5.392e-03-5.222Fe-2S-bd_dom_sfinterpro domainsIPR036884211852150 AOX1
5.392e-03-5.22Pleckstrininterpro domainsIPR037370211852150 PLEK
5.392e-03-5.22AldOxase/xan_DH_Mopterin-bd_sfinterpro domainsIPR037165211852150 AOX1
5.392e-03-5.22AldOxase/xan_DH_MoCoBD2interpro domainsIPR046867211852150 AOX1
5.392e-03-5.22FNIP_C_dominterpro domainsIPR028086211852150 FNIP1
5.395e-03-5.22cellular response to lipoprotein particle stimulusbiological processGO:00714024021820450 ABCA1,CD68
5.419e-03-5.22upper_aerodigestive_tractCOSMIC cancer mutationsupper_aerodigestive_tract13181431682846 FNIP1,DISC1,FCHO2,RHBDF1,MLKL,SH2B3,BLNK,ARHGEF1,MYO1F,ARAP1,MFSD1,FERMT3,FMNL1,CEBPB,CSF3R,TFEB,SRGN,SH3KBP1,RGL1,FLRT2,PLEK,HCK,ABCA1,BAZ2B,GLDC,MEF2C,ARAP3,RBM47,RXRA,ELF4,STAB1,MAN1A1,MARK4,SGMS1,ATP8A1,ETV6,DOCK4,ETS1,AOX1,DIAPH2,DAB2,ABCC5,MICAL2
5.437e-03-5.21SH3DOMAINprints domainsPR00452833522723 HCK,SH3KBP1,MYO1F
5.459e-03-5.21phosphatidylinositol-3,4,5-trisphosphate bindingmolecular functionGO:00055474021809450 ARAP3,ARAP1
5.459e-03-5.21FAD bindingmolecular functionGO:00719494021809450 AOX1,MICAL2
5.461e-03-5.21B cell differentiationbiological processGO:003018313031820450 ADGRG3,FNIP1,BLNK
5.471e-03-5.21RBBP5 (RB binding protein 5, histone lysine methyltransferase complex subunit)protein interactions592927641945450 FERMT3,BAZ2B,DISC1,ELF4
5.486e-03-5.21positive regulation of high-density lipoprotein particle assemblybiological processGO:0090108211820450 ABCA1
5.486e-03-5.21nephron tubule epithelial cell differentiationbiological processGO:0072160211820450 MEF2C
5.486e-03-5.21negative regulation of inositol phosphate biosynthetic processbiological processGO:0010920211820450 PLEK
5.486e-03-5.21negative regulation of Kit signaling pathwaybiological processGO:1900235211820450 SH2B3
5.486e-03-5.21positive regulation of alkaline phosphatase activitybiological processGO:0010694211820450 MEF2C
5.486e-03-5.21NK T cell activationbiological processGO:0051132211820450 ELF4
5.486e-03-5.21cAMP transportbiological processGO:0070730211820450 ABCC5
5.486e-03-5.21cellular response to trichostatin Abiological processGO:0035984211820450 MEF2C
5.486e-03-5.21sulfur oxidationbiological processGO:0019417211820450 MICAL2
5.486e-03-5.21NMDA selective glutamate receptor signaling pathwaybiological processGO:0098989211820450 MEF2C
5.486e-03-5.21mast cell secretory granule organizationbiological processGO:0033364211820450 SRGN
5.486e-03-5.21positive regulation of thyroid hormone mediated signaling pathwaybiological processGO:0002157211820450 RXRA
5.486e-03-5.21muscle cell fate determinationbiological processGO:0007521211820450 MEF2C
5.486e-03-5.21AMPA selective glutamate receptor signaling pathwaybiological processGO:0098990211820450 MEF2C
5.486e-03-5.21regulation of Kit signaling pathwaybiological processGO:1900234211820450 SH2B3
5.486e-03-5.21sinoatrial valve developmentbiological processGO:0003172211820450 MEF2C
5.486e-03-5.21execution phase of necroptosisbiological processGO:0097528211820450 MLKL
5.486e-03-5.21regulation of alkaline phosphatase activitybiological processGO:0010692211820450 MEF2C
5.486e-03-5.21response to trichostatin Abiological processGO:0035983211820450 MEF2C
5.486e-03-5.21NK T cell proliferationbiological processGO:0001866211820450 ELF4
5.500e-03-5.20Ets1_N_flankpfam domainsPF19525211779549 ETS1
5.500e-03-5.20FNIP_Mpfam domainsPF14637211779549 FNIP1
5.500e-03-5.20Ald_Xan_dh_Cpfam domainsPF01315211779549 AOX1
5.500e-03-5.20FAD_binding_5pfam domainsPF00941211779549 AOX1
5.500e-03-5.20Fer2_2pfam domainsPF01799211779549 AOX1
5.500e-03-5.20FNIP_Cpfam domainsPF14638211779549 FNIP1
5.500e-03-5.20CO_deh_flav_Cpfam domainsPF03450211779549 AOX1
5.500e-03-5.20MoCoBD_1pfam domainsPF02738211779549 AOX1
5.500e-03-5.20FNIP_Npfam domainsPF14636211779549 FNIP1
5.500e-03-5.20DAB2_SBMpfam domainsPF21792211779549 DAB2
5.500e-03-5.20MoCoBD_2pfam domainsPF20256211779549 AOX1
5.500e-03-5.20iRhom1-2_Npfam domainsPF12595211779549 RHBDF1
5.500e-03-5.20Nuc_recep-AF1pfam domainsPF11825211779549 RXRA
5.519e-03-5.20apolipoprotein A-I receptor activitymolecular functionGO:0034188211809450 ABCA1
5.535e-03-5.20bone-femur-chondrosarcomaCOSMIC cancer mutationsbone-femur-chondrosarcoma41951682846 BLNK,CSF3R,ABCA1,RBM47,DAB2
5.563e-03-5.19cell-substrate junctioncellular componentGO:003005543751910850 FLRT2,FERMT3,SH3KBP1,HCK,DAB2
5.575e-03-5.19SH2 domaingene3d domains3.30.505.1011131447047 BLNK,HCK,SH2B3
5.662e-03-5.17intracellular lipid transportbiological processGO:00323654121820450 ABCA1,CERT1
5.662e-03-5.17cortical actin cytoskeleton organizationbiological processGO:00308664121820450 PLEK,FMNL1
5.662e-03-5.17negative regulation of ossificationbiological processGO:00302794121820450 SRGN,MEF2C
5.696e-03-5.17MAPK7 (mitogen-activated protein kinase 7)protein interactions559814131945450 RXRA,ETS1,MEF2C
5.709e-03-5.17regulation of protein-containing complex assemblybiological processGO:004325441951820450 ABCA1,FNIP1,PLEK,HCK,MARK4
5.717e-03-5.16CCDC88B (coiled-coil domain containing 88B)protein interactions2832344421945450 SH3KBP1,HCK
5.717e-03-5.16Cargo recognition for clathrin-mediated endocytosisREACTOME pathwaysR-HSA-88568259931028538 SH3KBP1,DAB2,FCHO2
5.747e-03-5.16immune response-regulating cell surface receptor signaling pathwaybiological processGO:000276826241820450 BLNK,CD276,MEF2C,HCK
5.753e-03-5.16leukocyte activationbiological processGO:004532159961820450 CD276,ADGRG3,ELF4,BLNK,FNIP1,MEF2C
5.824e-03-5.15heart morphogenesisbiological processGO:000300726341820450 FLRT2,MICAL2,CERT1,MEF2C
5.832e-03-5.14SH3 Domainsgene3d domains2.30.30.4022341447047 DOCK4,MYO1F,SH3KBP1,HCK
5.973e-03-5.12SH3BP2 (SH3 domain binding protein 2)protein interactions64524521945450 SH3KBP1,MYO1F
5.973e-03-5.12WIPF1 (WAS/WASL interacting protein family member 1)protein interactions74564521945450 HCK,SH3KBP1
5.973e-03-5.12SPTBN4 (spectrin beta, non-erythrocytic 4)protein interactions577314521945450 ETS1,DISC1
5.986e-03-5.12positive regulation of transcription by RNA polymerase IIbiological processGO:0045944123791820450 TFEB,DAB2,ETV6,CEBPB,ELF4,RXRA,MICAL2,MEF2C,ETS1
5.994e-03-5.12Dorso-ventral axis formationKEGG pathwaysko04320282716130 ETV6,ETS1
5.994e-03-5.12Dorso-ventral axis formationKEGG pathwayshsa04320282716130 ETV6,ETS1
5.997e-03-5.12endomembrane systemcellular componentGO:00125054764211910850 ARHGAP45,FLRT2,DIAPH2,CD68,ATP8A1,ARAP1,SGMS1,CD53,HCK,ABCA1,FERMT3,DISC1,SRGN,RHBDF1,DAB2,CERT1,FCHO2,DOCK4,MAN1A1,ABCC5,ADGRG3
6.005e-03-5.12intramembrane lipid transporter activitymolecular functionGO:01403034221809450 ATP8A1,ABCA1
6.010e-03-5.11ABC_transporter-like_CSinterpro domainsIPR0178714321852150 ABCC5,ABCA1
6.081e-03-5.10REVINTRACTNGprints domainsPR00405272522723 ARAP3,ARAP1
6.087e-03-5.10regulation of cellular component biogenesisbiological processGO:0044087101681820450 FNIP1,PLEK,MEF2C,MARK4,ABCA1,FLRT2,ARAP1,HCK
6.213e-03-5.08regulation of cell adhesionbiological processGO:003015580771820450 ETS1,SH2B3,DAB2,CEBPB,CD276,DISC1,FERMT3
6.224e-03-5.08Transcriptional misregulation in cancerKEGG pathwaysko052021794716130 RXRA,MEF2C,ETV6,CEBPB
6.224e-03-5.08Transcriptional misregulation in cancerKEGG pathwayshsa052021794716130 ETV6,CEBPB,RXRA,MEF2C
6.420e-03-5.05secretory vesiclecellular componentGO:0099503107681910850 DISC1,ARHGAP45,SRGN,CD53,ADGRG3,FERMT3,CD68,ATP8A1
6.440e-03-5.05cellular component organization or biogenesisbiological processGO:00718405850251820450 ABCA1,SH3KBP1,HCK,ARAP3,CERT1,MARK4,FERMT3,FMNL1,SRGN,FCHO2,TFEB,ARAP1,MYO1F,ATP8A1,ETV6,MLKL,ETS1,FLRT2,DISC1,DAB2,DIAPH2,CTSV,BAZ2B,PLEK,MICAL2
6.486e-03-5.04Aldehyde oxidase/xanthine dehydrogenase, a/b hammerheadgene3d domains3.90.1170.50211447047 AOX1
6.486e-03-5.04Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding domaingene3d domains3.30.365.10211447047 AOX1
6.486e-03-5.04[2Fe-2S]-binding domaingene3d domains1.10.150.120211447047 AOX1
6.498e-03-5.04B cell receptor signaling pathwaybiological processGO:00508534421820450 MEF2C,BLNK
6.498e-03-5.04positive regulation of bone mineralizationbiological processGO:00305014421820450 RXRA,MEF2C
6.500e-03-5.04SH3BP1 (SH3 domain binding protein 1)protein interactions236164721945450 SH3KBP1,HCK
6.571e-03-5.03antigen receptor-mediated signaling pathwaybiological processGO:005085113931820450 MEF2C,BLNK,CD276
6.624e-03-5.02MCAM (melanoma cell adhesion molecule)protein interactions416246451945450 ABCC5,FLRT2,FERMT3,RHBDF1,DAB2
6.696e-03-5.01Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domaingene3d domains1.10.10.1023241447047 ETV6,ETS1,PLEK,ELF4
6.743e-03-5.00PFN1 (profilin 1)protein interactions521646651945450 ARHGEF1,DOCK4,FMNL1,FCHO2,DIAPH2
6.863e-03-4.98carcinoid-endocrine_tumourCOSMIC cancer mutationscarcinoid-endocrine_tumour7752301682846 BAZ2B,PLEK,HCK,ABCA1,GLDC,FNIP1,FCHO2,SH2B3,RXRA,ELF4,MLKL,MYO1F,BLNK,ARHGEF1,STAB1,MAN1A1,MARK4,SGMS1,ETV6,CD276,ATP8A1,AOX1,SRGN,FMNL1,CSF3R,RGL1,DIAPH2,ABCC5,MICAL2,SH3KBP1
6.891e-03-4.98positive regulation of response to stimulusbiological processGO:00485842266131820450 HCK,CEBPB,BLNK,RXRA,FNIP1,RBM47,MARK4,ETS1,DISC1,CD276,DAB2,CTSV,MEF2C
6.953e-03-4.97RAC2 (Rac family small GTPase 2)protein interactions588066661945450 DIAPH2,FLRT2,DAB2,FCHO2,FMNL1,ABCC5
7.147e-03-4.94SH2prosite domainsPS5000110731218645 HCK,BLNK,SH2B3
7.167e-03-4.94ABC-type transporter activitymolecular functionGO:01403594621809450 ABCC5,ABCA1
7.203e-03-4.93RHOF (ras homolog family member F, filopodia associated)protein interactions5450967161945450 DAB2,FCHO2,FMNL1,ABCC5,DIAPH2,FLRT2
7.242e-03-4.93amide transportbiological processGO:004288614431820450 ABCC5,CERT1,ABCA1
7.263e-03-4.92RAP1A (RAP1A, member of RAS oncogene family)protein interactions590615431945450 RGL1,CD53,ARHGEF1
7.312e-03-4.92regulation of cell activationbiological processGO:005086563061820450 PLEK,MEF2C,CEBPB,CD276,SH3KBP1,SH2B3
7.372e-03-4.91DENN_FNIP12prosite domainsPS51836211218645 FNIP1
7.443e-03-4.90ABC_transporter-like_ATP-bdinterpro domainsIPR0034394821852150 ABCC5,ABCA1
7.456e-03-4.90SH2smart domainsSM002521033971738 BLNK,SH2B3,HCK
7.501e-03-4.89intracellular membrane-bounded organellecellular componentGO:004323112479411910850 CD68,RXRA,CSF3R,MICAL2,FLRT2,ARHGAP45,ETS1,RBM47,FMNL1,ADGRG3,DOCK4,STAB1,MEF2C,FNIP1,TFEB,GLDC,BLNK,DISC1,DAB2,MFSD1,ETV6,ATP8A1,CEBPB,DIAPH2,BAZ2B,CTSV,FERMT3,ABCA1,CD53,HCK,ARAP1,SGMS1,SH3KBP1,ELF4,FCHO2,CERT1,MAN1A1,ABCC5,SRGN,MLKL,RHBDF1
7.560e-03-4.88vesicle-mediated transportbiological processGO:0016192128391820450 FCHO2,ARAP3,STAB1,DAB2,HCK,SH3KBP1,ABCA1,PLEK,MYO1F
7.673e-03-4.87small GTPase bindingmolecular functionGO:003126728341809450 ABCA1,DIAPH2,DOCK4,FMNL1
7.691e-03-4.87Dnm2 (dynamin 2)protein interactions13430311945450 SH3KBP1
7.691e-03-4.87Srr (serine racemase)protein interactions27364311945450 DISC1
7.691e-03-4.87Ppp1cc (protein phosphatase 1 catalytic subunit gamma)protein interactions19047311945450 SH3KBP1
7.691e-03-4.87Ubtf (upstream binding transcription factor, RNA polymerase I)protein interactions21429311945450 SH3KBP1
7.691e-03-4.87SPS100 (Sps100p)protein interactions856541311945450 CERT1
7.691e-03-4.87Pik3r1 (phosphoinositide-3-kinase regulatory subunit 1)protein interactions18708311945450 SH3KBP1
7.691e-03-4.87Grip1 (glutamate receptor interacting protein 1)protein interactions74053311945450 RXRA
7.691e-03-4.87SEMA3E (semaphorin 3E)protein interactions9723311945450 GLDC
7.691e-03-4.87Myo6 (myosin VI)protein interactions315840311945450 DAB2
7.691e-03-4.87Rad50 (RAD50 double strand break repair protein)protein interactions19360311945450 SH3KBP1
7.691e-03-4.87Cbl (Casitas B-lineage lymphoma)protein interactions12402311945450 SH3KBP1
7.691e-03-4.87HERC2P2 (HERC2 pseudogene 2)protein interactions400322311945450 DISC1
7.700e-03-4.87SH3smart domainsSM003262024971738 HCK,DOCK4,SH3KBP1,MYO1F
7.729e-03-4.86ABC_tranpfam domainsPF000054821779549 ABCA1,ABCC5
7.806e-03-4.85Ald_Xan_dh_Csmart domainsSM0100821971738 AOX1
7.806e-03-4.85CO_deh_flav_Csmart domainsSM0109221971738 AOX1
7.818e-03-4.85chronic_myelomonocytic_leukaemiaCOSMIC cancer mutationschronic_myelomonocytic_leukaemia14931682846 ETV6,SH2B3,CSF3R
7.818e-03-4.85haematopoietic_and_lymphoid_tissue-haematopoietic_neoplasm-chronic_myelomonocytic_leukaemiaCOSMIC cancer mutationshaematopoietic_and_lymphoid_tissue-haematopoietic_neoplasm-chronic_myelomonocytic_leukaemia14931682846 CSF3R,SH2B3,ETV6
7.830e-03-4.85CHOP-C/EBP complexcellular componentGO:0036488311910850 CEBPB
7.830e-03-4.85mast cell granulecellular componentGO:0042629311910850 SRGN
7.832e-03-4.85regulation of defense responsebiological processGO:003134784371820450 HCK,CEBPB,RBM47,MARK4,MEF2C,ETS1,ELF4
7.847e-03-4.85regulation of cell migrationbiological processGO:0030334106181820450 ATP8A1,MEF2C,ETS1,DAB2,DOCK4,FERMT3,ADGRG3,FLRT2
7.875e-03-4.84positive regulation of immune responsebiological processGO:005077864061820450 CD276,HCK,BLNK,RBM47,MEF2C,MARK4
7.902e-03-4.84azurophil granulecellular componentGO:004258215631910850 CD68,ARHGAP45,ATP8A1
7.902e-03-4.84primary lysosomecellular componentGO:000576615631910850 ARHGAP45,CD68,ATP8A1
7.953e-03-4.83embryonic organ developmentbiological processGO:004856845451820450 TFEB,MICAL2,MEF2C,CEBPB,SH2B3
8.007e-03-4.83platelet aggregationbiological processGO:00705274921820450 PLEK,FERMT3
8.078e-03-4.82Kindlin/fermitininterpro domainsIPR037843311852150 FERMT3
8.078e-03-4.822Fe2S_fd_BSinterpro domainsIPR006058311852150 AOX1
8.078e-03-4.82Kindlin_2_Ninterpro domainsIPR040790311852150 FERMT3
8.078e-03-4.82RGS-like_dominterpro domainsIPR015212311852150 ARHGEF1
8.078e-03-4.82Sphingomyelin_synth-like_dominterpro domainsIPR025749311852150 SGMS1
8.078e-03-4.82Phe_ZIP_sfinterpro domainsIPR036290311852150 SH2B3
8.078e-03-4.82SH2Binterpro domainsIPR030523311852150 SH2B3
8.078e-03-4.82FMNL_animalinterpro domainsIPR043592311852150 FMNL1
8.078e-03-4.82GPR1/GPR3/GPR5interpro domainsIPR003910311852150 ADGRG3
8.078e-03-4.82TF_Elf_Ninterpro domainsIPR022084311852150 ELF4
8.078e-03-4.82DIA_GBD_sfinterpro domainsIPR044933311852150 DIAPH2
8.078e-03-4.82LAMP_CSinterpro domainsIPR018134311852150 CD68
8.078e-03-4.82Muniscin_Cinterpro domainsIPR018808311852150 FCHO2
8.078e-03-4.82Phe_ZIPinterpro domainsIPR015012311852150 SH2B3
8.078e-03-4.82MiT/TFE_Ninterpro domainsIPR031867311852150 TFEB
8.078e-03-4.82Sphingomyelin_synth-likeinterpro domainsIPR045221311852150 SGMS1
8.078e-03-4.82PH_Kindlin/fermitininterpro domainsIPR037837311852150 FERMT3
8.078e-03-4.82OxRdtase_Mopterin_BSinterpro domainsIPR022407311852150 AOX1
8.179e-03-4.81congenital_(infantile)_fibrosarcomaCOSMIC cancer mutationscongenital_(infantile)_fibrosarcoma311682846 ETV6
8.179e-03-4.81soft_tissue-fibrous_tissue_and_uncertain_origin-hypertrophic_scarCOSMIC cancer mutationssoft_tissue-fibrous_tissue_and_uncertain_origin-hypertrophic_scar311682846 ETV6
8.179e-03-4.81soft_tissue-fibrous_tissue_and_uncertain_originCOSMIC cancer mutationssoft_tissue-fibrous_tissue_and_uncertain_origin311682846 BAZ2B
8.179e-03-4.81soft_tissue-fibrous_tissue_and_uncertain_origin-congenital_(infantile)_fibrosarcomaCOSMIC cancer mutationssoft_tissue-fibrous_tissue_and_uncertain_origin-congenital_(infantile)_fibrosarcoma311682846 ETV6
8.179e-03-4.81mammary_analogue_secretory_carcinoma_of_salivary_glandsCOSMIC cancer mutationsmammary_analogue_secretory_carcinoma_of_salivary_glands311682846 ETV6
8.179e-03-4.81hypertrophic_scarCOSMIC cancer mutationshypertrophic_scar311682846 ETV6
8.179e-03-4.81salivary_gland-parotid-carcinoma-mammary_analogue_secretory_carcinoma_of_salivary_glandsCOSMIC cancer mutationssalivary_gland-parotid-carcinoma-mammary_analogue_secretory_carcinoma_of_salivary_glands311682846 ETV6
8.218e-03-4.80response to vitamin B3biological processGO:0033552311820450 ABCA1
8.218e-03-4.80positive regulation of macrophage apoptotic processbiological processGO:2000111311820450 MEF2C
8.218e-03-4.80glycine catabolic processbiological processGO:0006546311820450 GLDC
8.218e-03-4.80primary heart field specificationbiological processGO:0003138311820450 MEF2C
8.218e-03-4.80positive regulation of mineralocorticoid secretionbiological processGO:2000857311820450 DAB2
8.218e-03-4.80positive regulation of aldosterone secretionbiological processGO:2000860311820450 DAB2
8.218e-03-4.80positive regulation of aldosterone biosynthetic processbiological processGO:0032349311820450 DAB2
8.218e-03-4.80pyramidal neuron migration to cerebral cortexbiological processGO:0021852311820450 DISC1
8.218e-03-4.80positive regulation of clathrin-dependent endocytosisbiological processGO:2000370311820450 DAB2
8.218e-03-4.80positive regulation of sodium-dependent phosphate transportbiological processGO:2000120311820450 CEBPB
8.218e-03-4.80positive regulation of B cell apoptotic processbiological processGO:0002904311820450 FNIP1
8.218e-03-4.80regulation of synaptic activitybiological processGO:0060025311820450 MEF2C
8.218e-03-4.80positive regulation of aldosterone metabolic processbiological processGO:0032346311820450 DAB2
8.218e-03-4.80heme transmembrane transportbiological processGO:0035351311820450 ABCC5
8.218e-03-4.80negative regulation of vascular associated smooth muscle contractionbiological processGO:1904694311820450 DOCK4
8.218e-03-4.80leukocyte migration involved in immune responsebiological processGO:0002522311820450 HCK
8.218e-03-4.80ER to Golgi ceramide transportbiological processGO:0035621311820450 CERT1
8.218e-03-4.80monocyte homeostasisbiological processGO:0035702311820450 SH2B3
8.218e-03-4.80glycine decarboxylation via glycine cleavage systembiological processGO:0019464311820450 GLDC
8.238e-03-4.80MITF_TFEB_C_3_Npfam domainsPF15951311779549 TFEB
8.238e-03-4.80Phe_ZIPpfam domainsPF08916311779549 SH2B3
8.238e-03-4.80PAP2_Cpfam domainsPF14360311779549 SGMS1
8.238e-03-4.80Elf-1_Npfam domainsPF12310311779549 ELF4
8.238e-03-4.80Kindlin_2_Npfam domainsPF18124311779549 FERMT3
8.238e-03-4.80RGS-likepfam domainsPF09128311779549 ARHGEF1
8.238e-03-4.80muHDpfam domainsPF10291311779549 FCHO2
8.268e-03-4.80sphingomyelin synthase activitymolecular functionGO:0033188311809450 SGMS1
8.268e-03-4.80aldehyde oxidase activitymolecular functionGO:0004031311809450 AOX1
8.268e-03-4.80apolipoprotein receptor activitymolecular functionGO:0030226311809450 ABCA1
8.268e-03-4.80ceramide phosphoethanolamine synthase activitymolecular functionGO:0002950311809450 SGMS1
8.268e-03-4.80ceramide cholinephosphotransferase activitymolecular functionGO:0047493311809450 SGMS1
8.268e-03-4.80vitamin D response element bindingmolecular functionGO:0070644311809450 RXRA
8.268e-03-4.80DNA binding domain bindingmolecular functionGO:0050692311809450 RXRA
8.327e-03-4.79cortical cytoskeleton organizationbiological processGO:00308655021820450 FMNL1,PLEK
8.327e-03-4.79phospholipid translocationbiological processGO:00453325021820450 ABCA1,ATP8A1
8.384e-03-4.78primary active transmembrane transporter activitymolecular functionGO:001539915131809450 ABCA1,ATP8A1,ABCC5
8.418e-03-4.78secretory granulecellular componentGO:003014189771910850 SRGN,ARHGAP45,CD53,FERMT3,ADGRG3,CD68,ATP8A1
8.468e-03-4.77specific granulecellular componentGO:004258116031910850 ATP8A1,ADGRG3,CD53
8.507e-03-4.77LCP2 (lymphocyte cytosolic protein 2)protein interactions39375421945450 BLNK,HCK
8.598e-03-4.76prostate-carcinoma-adenocarcinomaCOSMIC cancer mutationsprostate-carcinoma-adenocarcinoma12379411682846 ARAP3,MLKL,ELF4,RXRA,SH2B3,RBM47,ARHGEF1,CD53,BLNK,MYO1F,ABCA1,PLEK,FLRT2,BAZ2B,FCHO2,DISC1,FNIP1,GLDC,MEF2C,RHBDF1,CSF3R,DOCK4,FMNL1,SRGN,AOX1,TFEB,SH3KBP1,MICAL2,ABCC5,DIAPH2,DAB2,RGL1,SGMS1,MARK4,MAN1A1,ARAP1,STAB1,ATP8A1,CD276,ETV6,FERMT3
8.688e-03-4.75germ_cell_tumourCOSMIC cancer mutationsgerm_cell_tumour86771682846 HCK,FLRT2,MLKL,MARK4,STAB1,BAZ2B,FNIP1
8.752e-03-4.74signaling receptor complex adaptor activitymolecular functionGO:00301595121809450 BLNK,SH2B3
8.771e-03-4.74KLC2 (kinesin light chain 2)protein interactions6483716531945450 ARHGEF1,CEBPB,SH3KBP1
8.782e-03-4.74FOLLICULNIP1prints domainsPR0207321522723 FNIP1
8.814e-03-4.73VSTM1 (V-set and transmembrane domain containing 1)protein interactions2844155521945450 CD53,ADGRG3
8.846e-03-4.73positive regulation of hydrolase activitybiological processGO:005134546651820450 PLEK,ARAP1,ARHGAP45,CTSV,MEF2C
8.869e-03-4.73mouthCOSMIC cancer mutationsmouth9004331682846 ATP8A1,ETV6,FERMT3,SGMS1,MAN1A1,MARK4,ARAP1,STAB1,MICAL2,ABCC5,DIAPH2,CSF3R,ETS1,DOCK4,FMNL1,SRGN,AOX1,FCHO2,DISC1,FNIP1,GLDC,MEF2C,RHBDF1,ABCA1,HCK,PLEK,FLRT2,BAZ2B,ARHGEF1,MYO1F,ARAP3,RXRA,RBM47
8.907e-03-4.72SH3prosite domainsPS5000222241218645 MYO1F,DOCK4,HCK,SH3KBP1
8.926e-03-4.72CBL (Cbl proto-oncogene)protein interactions86749951945450 ARHGAP45,HCK,SH3KBP1,BLNK,MAN1A1
8.982e-03-4.71regulation of vascular associated smooth muscle cell migrationbiological processGO:19047525221820450 DOCK4,MEF2C
8.982e-03-4.71membrane invaginationbiological processGO:00103245221820450 FCHO2,ABCA1
8.985e-03-4.71positive regulation of biological processbiological processGO:00485186326261820450 DAB2,DISC1,FLRT2,PLEK,MICAL2,CTSV,ELF4,ETV6,CEBPB,ETS1,RXRA,CD53,DOCK4,TFEB,ARAP1,CD276,FERMT3,ATP8A1,MEF2C,HCK,SH3KBP1,ABCA1,RBM47,MARK4,BLNK,FNIP1
9.037e-03-4.71Antigen activates B Cell Receptor (BCR) leading to generation of second messengersREACTOME pathwaysR-HSA-9836953921028538 SH3KBP1,BLNK
9.130e-03-4.70AdipogenesisWikiPathwaysWP2361313531018 RXRA,MEF2C,CEBPB
9.133e-03-4.70SMARCA2 (SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2)protein interactions659532041945450 CEBPB,ETS1,ELF4,AOX1
9.318e-03-4.68regulation of platelet activationbiological processGO:00105435321820450 PLEK,SH2B3
9.395e-03-4.67immune response-activating signaling pathwaybiological processGO:000275730241820450 BLNK,CD276,MEF2C,HCK
9.401e-03-4.67secretory granule membranecellular componentGO:003066731741910850 CD53,ADGRG3,CD68,ATP8A1
9.442e-03-4.66SPI1 (Spi-1 proto-oncogene)protein interactions66885721945450 CEBPB,ETS1
9.509e-03-4.66HRAS (HRas proto-oncogene, GTPase)protein interactions326571261945450 CD276,SH3KBP1,FCHO2,RGL1,MICAL2,ARHGEF1
9.517e-03-4.65TGF-beta Signaling PathwayWikiPathwaysWP3661333531018 MEF2C,ETS1,DAB2
9.530e-03-4.65human chrXq21.33chromosome locationhuman chrXq21.33512613450 DIAPH2
9.550e-03-4.65DNA-binding transcription activator activity, RNA polymerase II-specificmolecular functionGO:000122847251809450 ELF4,ETS1,MEF2C,ETV6,CEBPB
9.557e-03-4.65haematopoietic_and_lymphoid_tissue-haematopoietic_neoplasm-myeloproliferative_neoplasmCOSMIC cancer mutationshaematopoietic_and_lymphoid_tissue-haematopoietic_neoplasm-myeloproliferative_neoplasm5421682846 SH2B3,CSF3R
9.557e-03-4.65myeloproliferative_neoplasmCOSMIC cancer mutationsmyeloproliferative_neoplasm5421682846 SH2B3,CSF3R
9.571e-03-4.65LYN (LYN proto-oncogene, Src family tyrosine kinase)protein interactions406771361945450 CSF3R,ABCC5,SH3KBP1,HCK,FCHO2,BLNK
9.659e-03-4.64positive regulation of ossificationbiological processGO:00457785421820450 MEF2C,RXRA
9.659e-03-4.64regulation of cholesterol effluxbiological processGO:00108745421820450 RXRA,ABCA1
9.659e-03-4.64regulation of alcohol biosynthetic processbiological processGO:19029305421820450 DAB2,PLEK
9.659e-03-4.64positive regulation of dephosphorylationbiological processGO:00353065421820450 PLEK,MEF2C
9.695e-03-4.64regulation of intracellular signal transductionbiological processGO:19025311832111820450 ABCA1,ARHGAP45,FNIP1,SH2B3,ADGRG3,SGMS1,ARAP1,DAB2,ARHGEF1,MEF2C,PLEK
9.709e-03-4.63HNRNPL (heterogeneous nuclear ribonucleoprotein L)protein interactions31911958111945450 SGMS1,RBM47,MICAL2,GLDC,RXRA,DAB2,DOCK4,FNIP1,ARAP1,BLNK,CERT1
9.713e-03-4.63-gene3d domains6.10.140.110311447047 SH2B3
9.713e-03-4.63-gene3d domains1.20.58.630311447047 DIAPH2
9.713e-03-4.63-gene3d domains6.10.30.30311447047 DIAPH2
9.713e-03-4.63Formin, diaphanous GTPase-binding domaingene3d domains1.10.20.40311447047 DIAPH2
9.713e-03-4.63CO dehydrogenase flavoprotein, C-terminal domaingene3d domains3.30.390.50311447047 AOX1
9.763e-03-4.63FLI1 (Fli-1 proto-oncogene, ETS transcription factor)protein interactions23135821945450 ETV6,FMNL1
9.763e-03-4.63CTXN3 (cortexin 3)protein interactions6132125821945450 ADGRG3,CD53
9.763e-03-4.63RRAGA (Ras related GTP binding A)protein interactions106705821945450 TFEB,FNIP1
9.827e-03-4.62regulation of small GTPase mediated signal transductionbiological processGO:005105630641820450 ABCA1,ARAP1,ARHGAP45,ARHGEF1
9.923e-03-4.61Mercaptopurine Action PathwaySMPDB pathwaysSMP000042845213695 ABCC5,AOX1
9.923e-03-4.61Thioguanine Action PathwaySMPDB pathwaysSMP000043045213695 ABCC5,AOX1
9.923e-03-4.61Azathioprine Action PathwaySMPDB pathwaysSMP000042745213695 ABCC5,AOX1
9.956e-03-4.61glycine cleavageBIOCYC pathwaysHUMAN_GLYCLEAV-PWY319023 GLDC
9.956e-03-4.61glycine cleavageBIOCYC pathwaysMETA_GLYCLEAV-PWY319023 GLDC
9.956e-03-4.61nicotine degradation VBIOCYC pathwaysMETA_PWY66-221319023 AOX1
9.956e-03-4.61glycine biosynthesis IIBIOCYC pathwaysMETA_GLYCINE-SYN2-PWY319023 GLDC
1.001e-02-4.60lipid translocationbiological processGO:00342045521820450 ABCA1,ATP8A1
1.001e-02-4.60intermembrane lipid transferbiological processGO:01200095521820450 ABCA1,CERT1
1.004e-02-4.60NCOR1 (nuclear receptor corepressor 1)protein interactions961132941945450 ETV6,CEBPB,RXRA,ETS1
1.005e-02-4.60DNA-binding transcription activator activitymolecular functionGO:000121647851809450 CEBPB,ETV6,ELF4,MEF2C,ETS1
1.009e-02-4.60TNKS2 (tankyrase 2)protein interactions803515921945450 ARAP3,DISC1
1.009e-02-4.60organellecellular componentGO:004322614500451910850 CD53,SH3KBP1,FERMT3,CEBPB,CTSV,ETV6,MFSD1,ATP8A1,SRGN,AOX1,MAN1A1,FCHO2,ELF4,ARHGAP45,FLRT2,MARK4,RXRA,CD68,TFEB,MEF2C,ADGRG3,FMNL1,ARAP3,HCK,ARAP1,SGMS1,ABCA1,DIAPH2,BAZ2B,RHBDF1,MLKL,ABCC5,CERT1,ETS1,MICAL2,CSF3R,MYO1F,DAB2,DISC1,BLNK,GLDC,FNIP1,STAB1,DOCK4,RBM47
1.010e-02-4.60central_nervous_system-brain-primitive_neuroectodermal_tumour-medulloblastoma-medullomyoblastomaCOSMIC cancer mutationscentral_nervous_system-brain-primitive_neuroectodermal_tumour-medulloblastoma-medullomyoblastoma48551682846 MICAL2,BAZ2B,DAB2,CSF3R,ATP8A1
1.010e-02-4.60medullomyoblastomaCOSMIC cancer mutationsmedullomyoblastoma48551682846 DAB2,BAZ2B,MICAL2,ATP8A1,CSF3R
1.015e-02-4.59receptor-mediated endocytosisbiological processGO:000689816331820450 FCHO2,STAB1,DAB2
1.024e-02-4.58Actn4 (actinin alpha 4)protein interactions60595411945450 SH3KBP1
1.024e-02-4.58Ap2a2 (adaptor-related protein complex 2, alpha 2 subunit)protein interactions11772411945450 SH3KBP1
1.024e-02-4.58CREG2 (cellular repressor of E1A stimulated genes 2)protein interactions200407411945450 GLDC
1.024e-02-4.58Slc25a12 (solute carrier family 25 (mitochondrial carrier, Aralar), member 12)protein interactions78830411945450 SH3KBP1
1.024e-02-4.58Ppp1ca (protein phosphatase 1 catalytic subunit alpha)protein interactions19045411945450 SH3KBP1
1.024e-02-4.58Khdrbs1 (KH domain containing, RNA binding, signal transduction associated 1)protein interactions20218411945450 SH3KBP1
1.024e-02-4.58MGAT3 (beta-1,4-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase)protein interactions4248411945450 DISC1
1.024e-02-4.58Cblb (Casitas B-lineage lymphoma b)protein interactions208650411945450 SH3KBP1
1.024e-02-4.58FBXO41 (F-box protein 41)protein interactions150726411945450 DISC1
1.024e-02-4.58Ap2m1 (adaptor-related protein complex 2, mu 1 subunit)protein interactions11773411945450 SH3KBP1
1.024e-02-4.58UNC5D (unc-5 netrin receptor D)protein interactions137970411945450 FLRT2
1.024e-02-4.58Net1 (neuroepithelial cell transforming gene 1)protein interactions56349411945450 SH3KBP1
1.024e-02-4.58Far1 (fatty acyl CoA reductase 1)protein interactions67420411945450 SH3KBP1
1.024e-02-4.58VGLL2 (vestigial like family member 2)protein interactions245806411945450 MEF2C
1.036e-02-4.57immune responsebiological processGO:0006955134991820450 CEBPB,HCK,TFEB,BLNK,ETS1,MEF2C,CERT1,CTSV,CD68
1.042e-02-4.56PSG11 (pregnancy specific beta-1-glycoprotein 11)protein interactions56806021945450 ARAP3,ARHGEF1
1.043e-02-4.56central region of growth conecellular componentGO:0090724411910850 DISC1
1.044e-02-4.56azurophil granule membranecellular componentGO:00355775921910850 CD68,ATP8A1
1.048e-02-4.56lipid transfer activitymolecular functionGO:01200135621809450 ABCA1,CERT1
1.061e-02-4.55PPARA activates gene expressionREACTOME pathwaysR-HSA-198978112431028538 ABCA1,RXRA,RGL1
1.070e-02-4.54regulation of signalingbiological processGO:00230513534171820450 DISC1,ADGRG3,SGMS1,ARAP1,DAB2,RHBDF1,PLEK,MEF2C,ARHGEF1,CTSV,ABCA1,ARHGAP45,RXRA,SH2B3,FNIP1,RBM47,MARK4
1.076e-02-4.53FAS1_domaininterpro domainsIPR000782411852150 STAB1
1.076e-02-4.53IgC2-like_lig-bdinterpro domainsIPR010457411852150 CSF3R
1.076e-02-4.53MADS_MEF2-likeinterpro domainsIPR033896411852150 MEF2C
1.076e-02-4.53Retinoid-X_rcpt/HNF4interpro domainsIPR000003411852150 RXRA
1.076e-02-4.53HJURP_Cinterpro domainsIPR022102411852150 MEF2C
1.076e-02-4.53C/EBP_chordatesinterpro domainsIPR016468411852150 CEBPB
1.076e-02-4.53MARK1-4_catinterpro domainsIPR049508411852150 MARK4
1.076e-02-4.53MiT/TFE_Cinterpro domainsIPR021802411852150 TFEB
1.076e-02-4.53FAS1_dom_sfinterpro domainsIPR036378411852150 STAB1
1.076e-02-4.53Adaptor_Cbl_N_dom_sfinterpro domainsIPR036537411852150 MLKL
1.077e-02-4.53CCL3 (C-C motif chemokine ligand 3)protein interactions634817831945450 CTSV,SRGN,CEBPB
1.082e-02-4.53regulation of cell motilitybiological processGO:2000145112281820450 ETS1,MEF2C,ATP8A1,ADGRG3,FLRT2,FERMT3,DOCK4,DAB2
1.084e-02-4.52lipid transporter activitymolecular functionGO:000531916631809450 CERT1,ABCA1,ATP8A1
1.089e-02-4.52kidney-other-mesoblastic_nephromaCOSMIC cancer mutationskidney-other-mesoblastic_nephroma411682846 ETV6
1.089e-02-4.52mesoblastic_nephromaCOSMIC cancer mutationsmesoblastic_nephroma411682846 ETV6
1.089e-02-4.52central_nervous_system-medulla-other-gangliogliomaCOSMIC cancer mutationscentral_nervous_system-medulla-other-ganglioglioma411682846 ETV6
1.089e-02-4.52central_nervous_system-middle_cerebellar_peduncle-other-gangliogliomaCOSMIC cancer mutationscentral_nervous_system-middle_cerebellar_peduncle-other-ganglioglioma411682846 ETV6
1.089e-02-4.52haematopoietic_and_lymphoid_tissue-other-idiopathic_erythrocytosisCOSMIC cancer mutationshaematopoietic_and_lymphoid_tissue-other-idiopathic_erythrocytosis411682846 SH2B3
1.089e-02-4.52central_nervous_system-midbrain-other-gangliogliomaCOSMIC cancer mutationscentral_nervous_system-midbrain-other-ganglioglioma411682846 ETV6
1.089e-02-4.52central_nervous_system-spinal_cord-other-gangliogliomaCOSMIC cancer mutationscentral_nervous_system-spinal_cord-other-ganglioglioma411682846 ETV6
1.089e-02-4.52middle_cerebellar_peduncleCOSMIC cancer mutationsmiddle_cerebellar_peduncle411682846 ETV6
1.089e-02-4.52idiopathic_erythrocytosisCOSMIC cancer mutationsidiopathic_erythrocytosis411682846 SH2B3
1.092e-02-4.52regulation of cell communicationbiological processGO:00106463541171820450 DISC1,ADGRG3,SGMS1,ARAP1,DAB2,RHBDF1,PLEK,CTSV,MEF2C,ARHGEF1,ABCA1,ARHGAP45,RXRA,FNIP1,SH2B3,RBM47,MARK4
1.094e-02-4.52HIVEP1 (HIVEP zinc finger 1)protein interactions309617931945450 SH3KBP1,RBM47,ETS1
1.094e-02-4.52negative regulation of lysosome organizationbiological processGO:1905672411820450 FNIP1
1.094e-02-4.52respiratory burst after phagocytosisbiological processGO:0045728411820450 HCK
1.094e-02-4.52regulation of high-density lipoprotein particle assemblybiological processGO:0090107411820450 ABCA1
1.094e-02-4.52epithelial cell proliferation involved in renal tubule morphogenesisbiological processGO:2001013411820450 MEF2C
1.094e-02-4.52negative regulation of CREB transcription factor activitybiological processGO:0032792411820450 ADGRG3
1.094e-02-4.52positive regulation of steroid hormone biosynthetic processbiological processGO:0090031411820450 DAB2
1.094e-02-4.52negative regulation of dendritic cell antigen processing and presentationbiological processGO:0002605411820450 CD68
1.094e-02-4.52vitellogenesisbiological processGO:0007296411820450 ETV6
1.094e-02-4.52protein localization to secretory granulebiological processGO:0033366411820450 SRGN
1.097e-02-4.51DUF3371pfam domainsPF11851411779549 TFEB
1.097e-02-4.51Fasciclinpfam domainsPF02469411779549 STAB1
1.097e-02-4.51Lep_receptor_Igpfam domainsPF06328411779549 CSF3R
1.097e-02-4.51DDTpfam domainsPF02791411779549 BAZ2B
1.097e-02-4.51HJURP_Cpfam domainsPF12347411779549 MEF2C
1.097e-02-4.51Fer2pfam domainsPF00111411779549 AOX1
1.101e-02-4.51stem cell factor receptor bindingmolecular functionGO:0005173411809450 SH2B3
1.101e-02-4.51sphingolipid floppase activitymolecular functionGO:0046623411809450 ABCA1
1.101e-02-4.51oxidoreductase activity, acting on the aldehyde or oxo group of donors, oxygen as acceptormolecular functionGO:0016623411809450 AOX1
1.101e-02-4.51phospholipid bindingmolecular functionGO:000554348951809450 CERT1,FCHO2,ARAP1,ARAP3,ABCA1
1.104e-02-4.51LAMP_2prosite domainsPS00311311218645 CD68
1.104e-02-4.51MOLYBDOPTERIN_EUKprosite domainsPS00559311218645 AOX1
1.104e-02-4.512FE2S_FER_1prosite domainsPS00197311218645 AOX1
1.104e-02-4.51Progressive trimming of alpha-1,2-linked mannose residues from Man9/8/7GlcNAc2 to produce Man5GlcNAc2REACTOME pathwaysR-HSA-964827311028538 MAN1A1
1.104e-02-4.51Vitamins B6 activation to pyridoxal phosphateREACTOME pathwaysR-HSA-964975311028538 AOX1
1.107e-02-4.50GTPase bindingmolecular functionGO:005102031541809450 DIAPH2,ABCA1,DOCK4,FMNL1
1.108e-02-4.50regulation of phosphatase activitybiological processGO:00109215821820450 MEF2C,PLEK
1.132e-02-4.48Regulation of lipid metabolism by Peroxisome proliferator-activated receptor alpha (PPARalpha)REACTOME pathwaysR-HSA-40020612731028538 ABCA1,RXRA,RGL1
1.133e-02-4.48actin cytoskeletoncellular componentGO:001562952051910850 MICAL2,DIAPH2,MYO1F,HCK,FERMT3
1.140e-02-4.47Sphingolipid de novo biosynthesisREACTOME pathwaysR-HSA-16606614421028538 SGMS1,CERT1
1.143e-02-4.47ABC_TRANSPORTER_1prosite domainsPS002114421218645 ABCC5,ABCA1
1.145e-02-4.47regulation of dendritic spine developmentbiological processGO:00609985921820450 MEF2C,DISC1
1.161e-02-4.46HCK (HCK proto-oncogene, Src family tyrosine kinase)protein interactions305518331945450 CSF3R,SH3KBP1,HCK
1.162e-02-4.46Diurnally Regulated Genes with Circadian OrthologsWikiPathwaysWP410492531018 ETV6,CEBPB
1.175e-02-4.44regulation of cell-cell adhesionbiological processGO:002240750051820450 CD276,FERMT3,SH2B3,ETS1,CEBPB
1.177e-02-4.44molecular function activator activitymolecular functionGO:0140677113281809450 FNIP1,ARAP3,ARHGEF1,FLRT2,ARAP1,CTSV,ARHGAP45,DOCK4
1.182e-02-4.44export across plasma membranebiological processGO:01401156021820450 ABCA1,ABCC5
1.191e-02-4.43Transcriptional activation of mitochondrial biogenesisREACTOME pathwaysR-HSA-21512014521028538 RXRA,MEF2C
1.213e-02-4.41molecular adaptor activitymolecular functionGO:0060090113881809450 SH2B3,MARK4,DAB2,BLNK,RBM47,FLRT2,DISC1,ETS1
1.220e-02-4.41negative regulation of G protein-coupled receptor signaling pathwaybiological processGO:00457446121820450 SH2B3,PLEK
1.235e-02-4.39protein kinase bindingmolecular functionGO:001990170161809450 MICAL2,SH2B3,PLEK,DOCK4,BLNK,MLKL
1.236e-02-4.39rufflecellular componentGO:000172618431910850 ARHGAP45,ARAP3,PLEK
1.256e-02-4.38Platelet degranulationREACTOME pathwaysR-HSA-11460813231028538 SRGN,FERMT3,PLEK
1.259e-02-4.38regulation of membrane lipid distributionbiological processGO:00970356221820450 ATP8A1,ABCA1
1.279e-02-4.36DENND2A (DENN domain containing 2A)protein interactions27147511945450 SH3KBP1
1.279e-02-4.36Hip1r (huntingtin interacting protein 1 related)protein interactions29816511945450 SH3KBP1
1.279e-02-4.36NPHS2 (NPHS2 stomatin family member, podocin)protein interactions7827511945450 SH3KBP1
1.279e-02-4.36ATP8B3 (ATPase phospholipid transporting 8B3)protein interactions148229511945450 ATP8A1
1.286e-02-4.35SP1 (Sp1 transcription factor)protein interactions666735441945450 RXRA,ETS1,CEBPB,MEF2C
1.287e-02-4.35NR1H2 (nuclear receptor subfamily 1 group H member 2)protein interactions73766721945450 RXRA,ABCA1
1.291e-02-4.35upper_aerodigestive_tract-mouth-carcinoma-squamous_cell_carcinomaCOSMIC cancer mutationsupper_aerodigestive_tract-mouth-carcinoma-squamous_cell_carcinoma6953271682846 FLRT2,HCK,ABCA1,MEF2C,GLDC,FNIP1,DISC1,FCHO2,RHBDF1,ARAP3,RBM47,RXRA,ARHGEF1,MYO1F,STAB1,ARAP1,ATP8A1,FERMT3,ETV6,FMNL1,DOCK4,CSF3R,ETS1,AOX1,SRGN,DIAPH2,MICAL2
1.293e-02-4.35Adaptor protein Cbl, N-terminal domaingene3d domains1.20.930.20411447047 MLKL
1.293e-02-4.35FAS1 domaingene3d domains2.30.180.10411447047 STAB1
1.298e-02-4.34TLE3 (TLE family member 3, transcriptional corepressor)protein interactions709035541945450 ETS1,CEBPB,BAZ2B,ETV6
1.299e-02-4.34membrane-bounded organellecellular componentGO:004322713662431910850 ADGRG3,STAB1,DOCK4,MEF2C,FNIP1,RBM47,FMNL1,DAB2,TFEB,GLDC,BLNK,DISC1,CD68,RXRA,ETS1,MARK4,CSF3R,MICAL2,FLRT2,ARHGAP45,MAN1A1,ABCC5,ELF4,FCHO2,CERT1,RHBDF1,AOX1,SRGN,MLKL,FERMT3,ABCA1,HCK,CD53,ARAP1,SH3KBP1,SGMS1,ETV6,MFSD1,ATP8A1,CEBPB,DIAPH2,CTSV,BAZ2B
1.302e-02-4.34apolipoprotein B mRNA editing enzyme complexcellular componentGO:0030895511910850 RBM47
1.315e-02-4.33GPR56ORPHANRprints domainsPR0142231522723 ADGRG3
1.328e-02-4.32phosphatidylinositol phosphate bindingmolecular functionGO:190198117931809450 FCHO2,ARAP1,ARAP3
1.331e-02-4.32regulation of locomotionbiological processGO:0040012116481820450 DAB2,DOCK4,FERMT3,ADGRG3,FLRT2,ATP8A1,MEF2C,ETS1
1.331e-02-4.32platelet alpha granule lumencellular componentGO:00310936721910850 FERMT3,SRGN
1.335e-02-4.32KHDRBS1 (KH RNA binding domain containing, signal transduction associated 1)protein interactions1065735841945450 GLDC,DISC1,HCK,SH3KBP1
1.337e-02-4.31actin polymerization or depolymerizationbiological processGO:00081546421820450 DIAPH2,MICAL2
1.343e-02-4.31HnRNP_R/Q_splicing_facinterpro domainsIPR006535511852150 RBM47
1.343e-02-4.31C/EBPinterpro domainsIPR031106511852150 CEBPB
1.343e-02-4.31WHIM2_dominterpro domainsIPR028941511852150 BAZ2B
1.343e-02-4.31KA1_dominterpro domainsIPR001772511852150 MARK4
1.343e-02-4.31TF_MADSbox_sfinterpro domainsIPR036879511852150 MEF2C
1.343e-02-4.31Lamp2-like_luminalinterpro domainsIPR048528511852150 CD68
1.343e-02-4.31FAD-bd_PCMH_sub1interpro domainsIPR016167511852150 AOX1
1.343e-02-4.31FAD-bdinterpro domainsIPR002938511852150 MICAL2
1.343e-02-4.31DOCK_Ninterpro domainsIPR032376511852150 DOCK4
1.343e-02-4.31DOCK_N_sub1interpro domainsIPR042455511852150 DOCK4
1.343e-02-4.31TF_MADSboxinterpro domainsIPR002100511852150 MEF2C
1.343e-02-4.31DDT_dominterpro domainsIPR018501511852150 BAZ2B
1.343e-02-4.31Lysosome-assoc_membr_glycopinterpro domainsIPR002000511852150 CD68
1.343e-02-4.31autonomic_ganglia-neuroblastomaCOSMIC cancer mutationsautonomic_ganglia-neuroblastoma3970181682846 MYO1F,DAB2,DIAPH2,BLNK,RBM47,ELF4,AOX1,DOCK4,RHBDF1,FNIP1,MEF2C,GLDC,ATP8A1,MARK4,STAB1,ARAP1,PLEK,ABCA1
1.347e-02-4.31neuroblastomaCOSMIC cancer mutationsneuroblastoma3971181682846 ABCA1,PLEK,STAB1,ARAP1,MARK4,ATP8A1,GLDC,MEF2C,FNIP1,RHBDF1,DOCK4,AOX1,ELF4,RBM47,BLNK,MYO1F,DIAPH2,DAB2
1.350e-02-4.30ABC_TRANSPORTER_2prosite domainsPS508934821218645 ABCC5,ABCA1
1.359e-02-4.30lipoblastomaCOSMIC cancer mutationslipoblastoma511682846 ETV6
1.359e-02-4.30central_nervous_system-brainstem-other-gangliogliomaCOSMIC cancer mutationscentral_nervous_system-brainstem-other-ganglioglioma511682846 ETV6
1.359e-02-4.30minorCOSMIC cancer mutationsminor511682846 ETV6
1.359e-02-4.30soft_tissue-fat-lipoblastomaCOSMIC cancer mutationssoft_tissue-fat-lipoblastoma511682846 ETV6
1.361e-02-4.30KANSL2 (KAT8 regulatory NSL complex subunit 2)protein interactions549346921945450 FERMT3,ELF4
1.366e-02-4.29regulation of sodium-dependent phosphate transportbiological processGO:2000118511820450 CEBPB
1.366e-02-4.29positive regulation of phospholipid translocationbiological processGO:0061092511820450 ATP8A1
1.366e-02-4.29thrombopoietin-mediated signaling pathwaybiological processGO:0038163511820450 SH2B3
1.366e-02-4.29natural killer cell proliferationbiological processGO:0001787511820450 ELF4
1.366e-02-4.29sphingolipid translocationbiological processGO:0099039511820450 ABCA1
1.366e-02-4.29folate transmembrane transportbiological processGO:0098838511820450 ABCC5
1.369e-02-4.29PRICHEXTENSNprints domainsPR01217412522723 FMNL1,CEBPB
1.369e-02-4.29SRF-TFpfam domainsPF00319511779549 MEF2C
1.369e-02-4.29WSDpfam domainsPF15613511779549 BAZ2B
1.369e-02-4.29DOCK_Npfam domainsPF16172511779549 DOCK4
1.369e-02-4.29FAD_binding_3pfam domainsPF01494511779549 MICAL2
1.369e-02-4.29KA1pfam domainsPF02149511779549 MARK4
1.369e-02-4.29Lamppfam domainsPF01299511779549 CD68
1.374e-02-4.29apolipoprotein A-I bindingmolecular functionGO:0034186511809450 ABCA1
1.374e-02-4.29phosphatidylserine flippase activitymolecular functionGO:0140346511809450 ATP8A1
1.374e-02-4.29glutathione transmembrane transporter activitymolecular functionGO:0034634511809450 ABCC5
1.374e-02-4.29ATPase inhibitor activitymolecular functionGO:0042030511809450 FNIP1
1.376e-02-4.29Myh9 (myosin, heavy polypeptide 9, non-muscle)protein interactions1788619531945450 SH3KBP1,FCHO2,DAB2
1.376e-02-4.29lung-carcinoma-squamous_cell_carcinomaCOSMIC cancer mutationslung-carcinoma-squamous_cell_carcinoma14664451682846 RHBDF1,MEF2C,GLDC,FNIP1,DISC1,FCHO2,BAZ2B,FLRT2,PLEK,HCK,ABCA1,MYO1F,BLNK,CD53,ARHGEF1,RBM47,RXRA,ELF4,MLKL,ARAP3,FERMT3,ETV6,MFSD1,CD276,ATP8A1,STAB1,ARAP1,MARK4,MAN1A1,SGMS1,RGL1,DIAPH2,DAB2,ABCC5,MICAL2,SH3KBP1,TFEB,CD68,AOX1,SRGN,FMNL1,DOCK4,CEBPB,CSF3R,ETS1
1.377e-02-4.29heart loopingbiological processGO:00019476521820450 MICAL2,MEF2C
1.388e-02-4.28Response to elevated platelet cytosolic Ca2+REACTOME pathwaysR-HSA-7600513731028538 SRGN,FERMT3,PLEK
1.388e-02-4.28Clathrin-mediated endocytosisREACTOME pathwaysR-HSA-885682813731028538 DAB2,FCHO2,SH3KBP1
1.399e-02-4.27ITGB3 (integrin subunit beta 3)protein interactions36907021945450 FERMT3,DAB2
1.399e-02-4.27ACTR5 (actin related protein 5)protein interactions799137021945450 ELF4,FMNL1
1.400e-02-4.27mixed_intestinal_and_diffuse_adenocarcinoma-unclassifiableCOSMIC cancer mutationsmixed_intestinal_and_diffuse_adenocarcinoma-unclassifiable95171682846 STAB1,SH2B3,FMNL1,HCK,FLRT2,FCHO2,MFSD1
1.400e-02-4.27stomach-carcinoma-mixed_intestinal_and_diffuse_adenocarcinoma-unclassifiableCOSMIC cancer mutationsstomach-carcinoma-mixed_intestinal_and_diffuse_adenocarcinoma-unclassifiable95171682846 MFSD1,FCHO2,HCK,FLRT2,FMNL1,SH2B3,STAB1
1.408e-02-4.26regulation of hydrolase activitybiological processGO:005133672661820450 ARAP1,ARHGAP45,PLEK,MEF2C,CTSV,FNIP1
1.418e-02-4.26homotypic cell-cell adhesionbiological processGO:00341096621820450 FERMT3,PLEK
1.418e-02-4.26secretory granule organizationbiological processGO:00333636621820450 SRGN,ABCA1
1.421e-02-4.25testisCOSMIC cancer mutationstestis73361682846 STAB1,MARK4,MLKL,FLRT2,HCK,FNIP1
1.437e-02-4.24ITGB3BP (integrin subunit beta 3 binding protein)protein interactions234217121945450 CERT1,RXRA
1.437e-02-4.24SRA1 (steroid receptor RNA activator 1)protein interactions100117121945450 ETS1,MLKL
1.439e-02-4.24ABC transportersKEGG pathwayshsa02010442716130 ABCC5,ABCA1
1.439e-02-4.24ABC transportersKEGG pathwaysko02010442716130 ABCA1,ABCC5
1.448e-02-4.23cell differentiationbiological processGO:00301543645171820450 CEBPB,HCK,ETV6,RBM47,ETS1,RXRA,BLNK,FNIP1,SH2B3,DAB2,DISC1,ADGRG3,FLRT2,PLEK,MEF2C,ELF4,DIAPH2
1.448e-02-4.23primitive_neuroectodermal_tumour-medulloblastomaCOSMIC cancer mutationsprimitive_neuroectodermal_tumour-medulloblastoma15350461682846 AOX1,DOCK4,ETS1,ABCC5,MICAL2,DIAPH2,DAB2,SGMS1,STAB1,MAN1A1,MARK4,ETV6,ATP8A1,CD276,RXRA,ELF4,RBM47,ARAP3,CD53,BAZ2B,ABCA1,FLRT2,PLEK,HCK,GLDC,MEF2C,CD68,SRGN,TFEB,FMNL1,CEBPB,CSF3R,RGL1,SH3KBP1,ARAP1,FERMT3,MFSD1,SH2B3,MLKL,MYO1F,ARHGEF1,BLNK,RHBDF1,DISC1,FCHO2,FNIP1
1.460e-02-4.23cellular developmental processbiological processGO:00488693648171820450 PLEK,MEF2C,ELF4,DIAPH2,DAB2,DISC1,ADGRG3,FLRT2,RBM47,ETS1,RXRA,BLNK,FNIP1,SH2B3,ETV6,HCK,CEBPB
1.469e-02-4.22FAS1prosite domainsPS50213411218645 STAB1
1.469e-02-4.22LAMP_3prosite domainsPS51407411218645 CD68
1.470e-02-4.22autonomic_gangliaCOSMIC cancer mutationsautonomic_ganglia4005181682846 ELF4,AOX1,RBM47,DOCK4,DIAPH2,DAB2,MYO1F,BLNK,MARK4,ARAP1,STAB1,ABCA1,PLEK,RHBDF1,ATP8A1,FNIP1,MEF2C,GLDC
1.470e-02-4.22Glycine degradationREACTOME pathwaysR-HSA-6783984411028538 GLDC
1.470e-02-4.22Scavenging by Class H ReceptorsREACTOME pathwaysR-HSA-3000497411028538 STAB1
1.491e-02-4.21DBN1 (drebrin 1)protein interactions162737041945450 DISC1,FCHO2,DAB2,GLDC
1.515e-02-4.19FCHO1 (FCH and mu domain containing endocytic adaptor 1)protein interactions231497321945450 FCHO2,DAB2
1.526e-02-4.18cellular response to lipidbiological processGO:007139653451820450 HCK,MEF2C,CD68,ABCA1,RXRA
1.532e-02-4.18RBP5 (retinol binding protein 5)protein interactions83758611945450 ABCC5
1.532e-02-4.18ATP8A2 (ATPase phospholipid transporting 8A2)protein interactions51761611945450 ATP8A1
1.532e-02-4.18Ncoa2 (nuclear receptor coactivator 2)protein interactions17978611945450 RXRA
1.554e-02-4.16GIMAP5 (GTPase, IMAP family member 5)protein interactions553407421945450 ADGRG3,CD53
1.555e-02-4.16FAS1smart domainsSM0055441971738 STAB1
1.560e-02-4.16mRNA editing complexcellular componentGO:0045293611910850 RBM47
1.561e-02-4.16CDC42 (cell division cycle 42)protein interactions998128081945450 FCHO2,FMNL1,ABCC5,ARAP1,DIAPH2,ABCA1,MARK4,FLRT2
1.585e-02-4.14determination of heart left/right asymmetrybiological processGO:00613717021820450 MEF2C,MICAL2
1.594e-02-4.14cell developmentbiological processGO:00484682236121820450 FLRT2,ADGRG3,DISC1,DIAPH2,MEF2C,PLEK,CEBPB,ETV6,FNIP1,SH2B3,BLNK,RBM47
1.594e-02-4.14Cd2ap (CD2-associated protein)protein interactions124887521945450 SH3KBP1,ARAP1
1.609e-02-4.132Fe-2S_ferredoxin-like_sfinterpro domainsIPR036010611852150 AOX1
1.609e-02-4.13FAD-bd_PCMH_sub2interpro domainsIPR016169611852150 AOX1
1.609e-02-4.13FAD-bd_PCMH-like_sfinterpro domainsIPR036318611852150 AOX1
1.609e-02-4.13FAD-bd_PCMHinterpro domainsIPR016166611852150 AOX1
1.609e-02-4.132Fe-2S_ferredoxin-typeinterpro domainsIPR001041611852150 AOX1
1.613e-02-4.13GTSE1 (G2 and S-phase expressed 1)protein interactions5151220731945450 SH3KBP1,DAB2,FCHO2
1.614e-02-4.13Transcription factor, MADS-boxgene3d domains3.40.1810.10511447047 MEF2C
1.614e-02-4.13Dedicator of cytokinesis N-terminal subdomaingene3d domains1.20.1270.350511447047 DOCK4
1.614e-02-4.13Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase, domain 2gene3d domains3.30.43.10511447047 AOX1
1.614e-02-4.13Formin, FH3 diaphanous domaingene3d domains1.10.238.150511447047 DIAPH2
1.615e-02-4.13organelle organizationbiological processGO:00069963091151820450 ABCA1,SH3KBP1,ARAP3,ETS1,CERT1,MARK4,FMNL1,SRGN,DISC1,ARAP1,TFEB,DIAPH2,MYO1F,MICAL2,PLEK
1.624e-02-4.12EGF/EGFR Signaling PathwayWikiPathwaysWP4371623531018 MEF2C,ARHGEF1,SH3KBP1
1.628e-02-4.12embryonic heart tube morphogenesisbiological processGO:00031437121820450 MEF2C,MICAL2
1.629e-02-4.12soft_tissue-fibrous_tissue_and_uncertain_origin-nodular_fasciitisCOSMIC cancer mutationssoft_tissue-fibrous_tissue_and_uncertain_origin-nodular_fasciitis611682846 ETV6
1.629e-02-4.12nodular_fasciitisCOSMIC cancer mutationsnodular_fasciitis611682846 ETV6
1.633e-02-4.11boneCOSMIC cancer mutationsbone8157301682846 MICAL2,ABCC5,DIAPH2,DAB2,SH3KBP1,CD68,AOX1,CSF3R,FMNL1,DOCK4,ETV6,ATP8A1,MFSD1,MARK4,STAB1,ARAP1,MYO1F,ARHGEF1,BLNK,ELF4,RBM47,MLKL,RHBDF1,FNIP1,GLDC,MEF2C,BAZ2B,ABCA1,HCK,FLRT2
1.635e-02-4.11RUNX2 (RUNX family transcription factor 2)protein interactions8607621945450 CEBPB,ETS1
1.637e-02-4.11regulation of aldosterone secretionbiological processGO:2000858611820450 DAB2
1.637e-02-4.11regulation of phospholipid translocationbiological processGO:0061091611820450 ATP8A1
1.637e-02-4.11positive regulation of vitamin D receptor signaling pathwaybiological processGO:0070564611820450 RXRA
1.637e-02-4.11apolipoprotein A-I-mediated signaling pathwaybiological processGO:0038027611820450 ABCA1
1.637e-02-4.11cell adhesion involved in heart morphogenesisbiological processGO:0061343611820450 FLRT2
1.637e-02-4.11radial glia-guided pyramidal neuron migrationbiological processGO:0140650611820450 DISC1
1.637e-02-4.11regulation of mineralocorticoid secretionbiological processGO:2000855611820450 DAB2
1.645e-02-4.11papillary_renal_cell_carcinomaCOSMIC cancer mutationspapillary_renal_cell_carcinoma6364251682846 SH2B3,RBM47,MLKL,ARAP3,MYO1F,CD53,BAZ2B,FLRT2,HCK,ABCA1,GLDC,FNIP1,FCHO2,AOX1,DOCK4,ETS1,RGL1,DAB2,ABCC5,SH3KBP1,ARAP1,STAB1,MARK4,FERMT3,MFSD1
1.645e-02-4.11kidney-carcinoma-papillary_renal_cell_carcinomaCOSMIC cancer mutationskidney-carcinoma-papillary_renal_cell_carcinoma6364251682846 MYO1F,CD53,RBM47,SH2B3,MLKL,ARAP3,FNIP1,GLDC,FCHO2,BAZ2B,HCK,FLRT2,ABCA1,DAB2,RGL1,ABCC5,SH3KBP1,AOX1,ETS1,DOCK4,FERMT3,MFSD1,MARK4,STAB1,ARAP1
1.647e-02-4.11type 1 angiotensin receptor bindingmolecular functionGO:0031702611809450 ARAP1
1.647e-02-4.11molybdopterin cofactor bindingmolecular functionGO:0043546611809450 AOX1
1.647e-02-4.11retinoic acid-responsive element bindingmolecular functionGO:0044323611809450 RXRA
1.654e-02-4.10skin-leg-malignant_melanomaCOSMIC cancer mutationsskin-leg-malignant_melanoma54951682846 MLKL,HCK,SGMS1,STAB1,DIAPH2
1.656e-02-4.10nicotine degradation IVBIOCYC pathwaysMETA_PWY66-201519023 AOX1
1.672e-02-4.09negative regulation of protein bindingbiological processGO:00320917221820450 DISC1,DAB2
1.686e-02-4.08Mitochondrial biogenesisREACTOME pathwaysR-HSA-15922305421028538 RXRA,MEF2C
1.709e-02-4.07human chr12q24.12chromosome locationhuman chr12q24.12912613450 SH2B3
1.715e-02-4.07TRIM24 (tripartite motif containing 24)protein interactions880538641945450 ETS1,RXRA,MLKL,ELF4
1.718e-02-4.06SEC23B (SEC23 homolog B, COPII coat complex component)protein interactions1048321231945450 DAB2,MAN1A1,GLDC
1.733e-02-4.06clathrin-coated pitcellular componentGO:00059057721910850 DAB2,FCHO2
1.737e-02-4.05regulation of cellular processbiological processGO:005079411468391820450 DAB2,SGMS1,FLRT2,DISC1,CTSV,BAZ2B,PLEK,MICAL2,ELF4,ETV6,CEBPB,ARHGAP45,ETS1,MLKL,CD53,RXRA,DOCK4,TFEB,ARAP1,RGL1,ADGRG3,FERMT3,SRGN,CD276,MEF2C,ARHGEF1,ATP8A1,RHBDF1,HCK,ARAP3,CSF3R,ABCA1,SH3KBP1,CERT1,MARK4,RBM47,FNIP1,SH2B3,BLNK
1.748e-02-4.05positive regulation of immune system processbiological processGO:000268498671820450 RBM47,MARK4,MEF2C,BLNK,HCK,CD276,SH3KBP1
1.749e-02-4.05RETINOIDXRprints domainsPR0054541522723 RXRA
1.749e-02-4.05LYSASSOCTDMPprints domainsPR0033641522723 CD68
1.760e-02-4.04upper_aerodigestive_tract-pharynx-carcinoma-squamous_cell_carcinomaCOSMIC cancer mutationsupper_aerodigestive_tract-pharynx-carcinoma-squamous_cell_carcinoma148591682846 ARHGEF1,MEF2C,MICAL2,ABCC5,DIAPH2,DAB2,ETS1,DOCK4,SGMS1
1.762e-02-4.04TRAF2 (TNF receptor associated factor 2)protein interactions718659251945450 MLKL,SH3KBP1,ETV6,BAZ2B,RXRA
1.772e-02-4.03skin-head_neck-carcinoma-squamous_cell_carcinomaCOSMIC cancer mutationsskin-head_neck-carcinoma-squamous_cell_carcinoma14191441682846 MYO1F,ARHGEF1,BLNK,SH2B3,MLKL,RHBDF1,DISC1,FCHO2,FNIP1,RGL1,SH3KBP1,CD68,SRGN,TFEB,FMNL1,CSF3R,FERMT3,MFSD1,ARAP1,CD53,RXRA,ELF4,RBM47,ARAP3,GLDC,MEF2C,BAZ2B,ABCA1,FLRT2,PLEK,HCK,ABCC5,MICAL2,DIAPH2,DAB2,AOX1,DOCK4,ETS1,ETV6,ATP8A1,SGMS1,STAB1,MARK4,MAN1A1
1.786e-02-4.03SOX18 (SRY-box transcription factor 18)protein interactions54345711945450 MEF2C
1.786e-02-4.03DDN (dendrin)protein interactions23109711945450 SH3KBP1
1.786e-02-4.03IL4 (interleukin 4)protein interactions3565711945450 CD53
1.786e-02-4.03ALG1L1P (ALG1 like 1, pseudogene)protein interactions200810711945450 ARAP3
1.786e-02-4.03Sptan1 (spectrin alpha, non-erythrocytic 1)protein interactions20740711945450 SH3KBP1
1.786e-02-4.03Otud5 (OTU domain containing 5)protein interactions54644711945450 FMNL1
1.786e-02-4.03MYT1L (myelin transcription factor 1 like)protein interactions23040711945450 DISC1
1.786e-02-4.03Gadd45b (growth arrest and DNA-damage-inducible 45 beta)protein interactions17873711945450 RXRA
1.786e-02-4.03ZCCHC24 (zinc finger CCHC-type containing 24)protein interactions219654711945450 RBM47
1.793e-02-4.02AH/BAR_dom_sfinterpro domainsIPR0272677621852150 ARHGAP45,FCHO2
1.797e-02-4.02HNRNPC (heterogeneous nuclear ribonucleoprotein C)protein interactions318359551945450 GLDC,RBM47,DISC1,HCK,SH3KBP1
1.801e-02-4.02STX2 (syntaxin 2)protein interactions20548021945450 CD53,CERT1
1.815e-02-4.01Vitamin B6 MetabolismSMPDB pathwaysSMP00000175113695 AOX1
1.815e-02-4.01HypophosphatasiaSMPDB pathwaysSMP00005035113695 AOX1
1.823e-02-4.00immune response-regulating signaling pathwaybiological processGO:000276436841820450 CD276,BLNK,HCK,MEF2C
1.823e-02-4.00activation of immune responsebiological processGO:000225336841820450 BLNK,CD276,MEF2C,HCK
1.824e-02-4.00inflammatory responsebiological processGO:000695455951820450 BLNK,STAB1,CD68,CEBPB,HCK
1.828e-02-4.00regulation of molecular functionbiological processGO:00650092005111820450 ADGRG3,DISC1,HCK,ARAP1,DAB2,ARHGAP45,FNIP1,RXRA,CTSV,MEF2C,PLEK
1.828e-02-4.00protein-macromolecule adaptor activitymolecular functionGO:003067498971809450 RBM47,MARK4,DAB2,SH2B3,ETS1,BLNK,FLRT2
1.829e-02-4.00ovary-other-neoplasmCOSMIC cancer mutationsovary-other-neoplasm12717411682846 SH3KBP1,RGL1,DAB2,DIAPH2,ABCC5,MICAL2,FMNL1,DOCK4,ETS1,CSF3R,CEBPB,TFEB,AOX1,SRGN,ATP8A1,FERMT3,ETV6,STAB1,ARAP1,MAN1A1,SGMS1,BLNK,CD53,ARHGEF1,MYO1F,MLKL,ARAP3,RBM47,SH2B3,RXRA,ELF4,GLDC,MEF2C,FNIP1,FCHO2,RHBDF1,FLRT2,PLEK,HCK,ABCA1,BAZ2B
1.833e-02-4.00pleura-mesothelioma-biphasicCOSMIC cancer mutationspleura-mesothelioma-biphasic7621682846 SH2B3,FNIP1
1.833e-02-4.00MADS_BOX_1prosite domainsPS00350511218645 MEF2C
1.833e-02-4.00KA1prosite domainsPS50032511218645 MARK4
1.833e-02-4.00MADS_BOX_2prosite domainsPS50066511218645 MEF2C
1.833e-02-4.00DDTprosite domainsPS50827511218645 BAZ2B
1.834e-02-4.00Hyaluronan biosynthesis and exportREACTOME pathwaysR-HSA-2142850511028538 ABCC5
1.834e-02-4.00Reelin signalling pathwayREACTOME pathwaysR-HSA-8866376511028538 SH3KBP1
1.834e-02-4.00N-glycan trimming and elongation in the cis-GolgiREACTOME pathwaysR-HSA-964739511028538 MAN1A1
1.843e-02-3.99DNMT3L (DNA methyltransferase 3 like)protein interactions299478121945450 RXRA,ETS1
1.847e-02-3.99regulation of multicellular organismal developmentbiological processGO:2000026148491820450 STAB1,CSF3R,CEBPB,DISC1,SRGN,FLRT2,ETS1,MEF2C,RXRA
1.866e-02-3.98cell projectioncellular componentGO:00429952398121910850 FERMT3,HCK,SH3KBP1,MYO1F,ARAP3,PLEK,MARK4,ARHGAP45,FLRT2,DOCK4,FMNL1,DISC1
1.871e-02-3.98MGA (MAX dimerization protein MGA)protein interactions2326921931945450 ELF4,ARHGEF1,ETS1
1.874e-02-3.98upper_aerodigestive_tract-mouth-carcinomaCOSMIC cancer mutationsupper_aerodigestive_tract-mouth-carcinoma6426251682846 RHBDF1,GLDC,FCHO2,BAZ2B,HCK,PLEK,FLRT2,ABCA1,MYO1F,ARHGEF1,RBM47,ARAP3,FERMT3,ATP8A1,MAN1A1,MARK4,ARAP1,STAB1,SGMS1,DIAPH2,MICAL2,ABCC5,AOX1,FMNL1,DOCK4
1.875e-02-3.98MYSc_Myo1interpro domainsIPR036072711852150 MYO1F
1.875e-02-3.98PH_16interpro domainsIPR041020711852150 ARHGEF1
1.875e-02-3.98KA1/Ssp2_Cinterpro domainsIPR028375711852150 MARK4
1.875e-02-3.98Glyco_hydro_47interpro domainsIPR001382711852150 MAN1A1
1.875e-02-3.98Seven-hairpin_glycosidasesinterpro domainsIPR036026711852150 MAN1A1
1.875e-02-3.98Prot_inhib_I29interpro domainsIPR013201711852150 CTSV
1.875e-02-3.98Hematopoietin_rcpt_Gp130_CSinterpro domainsIPR003529711852150 CSF3R
1.886e-02-3.97STAT6 (signal transducer and activator of transcription 6)protein interactions67788221945450 CEBPB,ETS1
1.886e-02-3.97GINM1 (glycosylated integral membrane protein 1)protein interactions1162548221945450 CTSV,MAN1A1
1.886e-02-3.97PALS1 (protein associated with LIN7 1, MAGUK p55 family member)protein interactions643988221945450 GLDC,SH3KBP1
1.886e-02-3.97MEF2D (myocyte enhancer factor 2D)protein interactions42098221945450 MEF2C,RXRA
1.888e-02-3.97positive regulation of response to external stimulusbiological processGO:003210356451820450 MARK4,HCK,ETS1,CEBPB,RBM47
1.898e-02-3.96regulation of synaptic transmission, glutamatergicbiological processGO:00519667721820450 DISC1,MEF2C
1.898e-02-3.96regulation of cholesterol transportbiological processGO:00323747721820450 RXRA,ABCA1
1.898e-02-3.96regulation of sterol transportbiological processGO:00323717721820450 ABCA1,RXRA
1.907e-02-3.96mannose trimming involved in glycoprotein ERAD pathwaybiological processGO:1904382711820450 MAN1A1
1.907e-02-3.96positive regulation of behavioral fear responsebiological processGO:2000987711820450 MEF2C
1.907e-02-3.96protein alpha-1,2-demannosylationbiological processGO:0036508711820450 MAN1A1
1.907e-02-3.96positive regulation of skeletal muscle cell differentiationbiological processGO:2001016711820450 MEF2C
1.907e-02-3.96PML body organizationbiological processGO:0030578711820450 ETS1
1.907e-02-3.96protein demannosylationbiological processGO:0036507711820450 MAN1A1
1.907e-02-3.96hyaluronan biosynthetic processbiological processGO:0030213711820450 ABCC5
1.907e-02-3.96aminophospholipid translocationbiological processGO:0140331711820450 ATP8A1
1.907e-02-3.96regulation of phosphate transportbiological processGO:0010966711820450 CEBPB
1.907e-02-3.96hepatocyte proliferationbiological processGO:0072574711820450 CEBPB
1.907e-02-3.96regulation of thyroid hormone mediated signaling pathwaybiological processGO:0002155711820450 RXRA
1.907e-02-3.96ubiquitin-dependent glycoprotein ERAD pathwaybiological processGO:0097466711820450 MAN1A1
1.907e-02-3.96cellular response to interleukin-3biological processGO:0036016711820450 SH2B3
1.907e-02-3.96glutathione transmembrane transportbiological processGO:0034775711820450 ABCC5
1.907e-02-3.96ceramide 1-phosphate transportbiological processGO:1902389711820450 CERT1
1.907e-02-3.96platelet degranulationbiological processGO:0002576711820450 PLEK
1.907e-02-3.96epithelial cell proliferation involved in liver morphogenesisbiological processGO:0072575711820450 CEBPB
1.907e-02-3.96positive regulation of corticosteroid hormone secretionbiological processGO:2000848711820450 DAB2
1.907e-02-3.96protein deglycosylation involved in glycoprotein catabolic processbiological processGO:0035977711820450 MAN1A1
1.907e-02-3.96positive regulation of protein localization to centrosomebiological processGO:1904781711820450 MARK4
1.907e-02-3.96response to interleukin-3biological processGO:0036015711820450 SH2B3
1.912e-02-3.96Glyco_hydro_47pfam domainsPF01532711779549 MAN1A1
1.912e-02-3.96PH_16pfam domainsPF17838711779549 ARHGEF1
1.912e-02-3.96Inhibitor_I29pfam domainsPF08246711779549 CTSV
1.915e-02-3.96GSK3B (glycogen synthase kinase 3 beta)protein interactions293283161945450 DISC1,CEBPB,FNIP1,DAB2,CSF3R,RXRA
1.919e-02-3.95mannosyl-oligosaccharide 1,2-alpha-mannosidase activitymolecular functionGO:0004571711809450 MAN1A1
1.919e-02-3.95aminophospholipid flippase activitymolecular functionGO:0015247711809450 ATP8A1
1.919e-02-3.95LBD domain bindingmolecular functionGO:0050693711809450 RXRA
1.919e-02-3.95ceramide 1-phosphate transfer activitymolecular functionGO:1902388711809450 CERT1
1.919e-02-3.95tripeptide transmembrane transporter activitymolecular functionGO:0042937711809450 ABCC5
1.919e-02-3.95ceramide 1-phosphate bindingmolecular functionGO:1902387711809450 CERT1
1.930e-02-3.95TMEM30B (transmembrane protein 30B)protein interactions1612918321945450 MAN1A1,CD276
1.930e-02-3.95N4BP2 (NEDD4 binding protein 2)protein interactions557288321945450 RBM47,DISC1
1.930e-02-3.95GGA2 (golgi associated, gamma adaptin ear containing, ARF binding protein 2)protein interactions230628321945450 ETS1,STAB1
1.930e-02-3.95CYBC1 (cytochrome b-245 chaperone 1)protein interactions794158321945450 ETS1,CD53
1.930e-02-3.95R3HDM1 (R3H domain containing 1)protein interactions235188321945450 RBM47,GLDC
1.933e-02-3.95-gene3d domains3.30.465.10611447047 AOX1
1.933e-02-3.95-gene3d domains2.40.160.110611447047 CD68
1.940e-02-3.94DDTsmart domainsSM0057151971738 BAZ2B
1.940e-02-3.94MADSsmart domainsSM0043251971738 MEF2C
1.944e-02-3.94positive regulation of osteoblast differentiationbiological processGO:00456697821820450 MEF2C,CEBPB
1.974e-02-3.93SRF (serum response factor)protein interactions67228421945450 RXRA,CEBPB
1.974e-02-3.93NFKBIB (NFKB inhibitor beta)protein interactions47938421945450 RXRA,ARAP3
1.974e-02-3.93Chmp4b (charged multivesicular body protein 4B)protein interactions756088421945450 BAZ2B,FNIP1
1.974e-02-3.93PTAR1 (protein prenyltransferase alpha subunit repeat containing 1)protein interactions3757438421945450 SGMS1,CERT1
1.983e-02-3.92large_intestine-colon-carcinomaCOSMIC cancer mutationslarge_intestine-colon-carcinoma2612131682846 DAB2,MYO1F,RGL1,MICAL2,ARHGEF1,AOX1,MLKL,ETV6,FNIP1,ATP8A1,BAZ2B,ARAP1,ABCA1
1.990e-02-3.92Endochondral OssificationWikiPathwaysWP474652531018 CTSV,MEF2C
1.991e-02-3.92myeloid cell developmentbiological processGO:00615157921820450 CEBPB,SH2B3
1.991e-02-3.92CLTC (clathrin heavy chain)protein interactions121361151945450 FCHO2,DAB2,SH3KBP1,GLDC,ARHGEF1
2.018e-02-3.90Nicotine MetabolismWikiPathwaysWP160061531018 AOX1
2.032e-02-3.90TGM2 (transglutaminase 2)protein interactions705222631945450 ABCA1,CERT1,DISC1
2.038e-02-3.89CNIH2 (cornichon family AMPA receptor auxiliary protein 2)protein interactions254263811945450 CD53
2.038e-02-3.89CD37 (CD37 molecule)protein interactions951811945450 CD53
2.038e-02-3.89Ap2b1 (adaptor-related protein complex 2, beta 1 subunit)protein interactions71770811945450 SH3KBP1
2.038e-02-3.89Fem1b (fem 1 homolog b)protein interactions14155811945450 FNIP1
2.038e-02-3.89MINAR1 (membrane integral NOTCH2 associated receptor 1)protein interactions23251811945450 CERT1
2.038e-02-3.89KMO (kynurenine 3-monooxygenase)protein interactions8564811945450 DISC1
2.040e-02-3.89HSPH1 (heat shock protein family H (Hsp110) member 1)protein interactions1080840741945450 SH3KBP1,DAB2,BLNK,GLDC
2.042e-02-3.89RAC3 (Rac family small GTPase 3)protein interactions588161551945450 FCHO2,ARAP3,DIAPH2,ABCC5,FLRT2
2.042e-02-3.89UBE2I (ubiquitin conjugating enzyme E2 I)protein interactions732961551945450 RXRA,ETS1,SH3KBP1,ETV6,MEF2C
2.042e-02-3.89positive regulation of cell activationbiological processGO:005086738141820450 CD276,SH3KBP1,MEF2C,PLEK
2.063e-02-3.88RBFOX1 (RNA binding fox-1 homolog 1)protein interactions547158621945450 RBM47,CTSV
2.063e-02-3.88SYNJ1 (synaptojanin 1)protein interactions88678621945450 SH3KBP1,RBM47
2.064e-02-3.88negative regulation of cell population proliferationbiological processGO:000828579161820450 FNIP1,SH2B3,MEF2C,ETS1,CEBPB,DAB2
2.075e-02-3.88presynaptic endocytic zone membranecellular componentGO:0098835811910850 FCHO2
2.092e-02-3.87positive regulation of macromolecule metabolic processbiological processGO:00106043485161820450 BLNK,RXRA,FNIP1,RBM47,ETS1,CEBPB,ETV6,ELF4,MICAL2,MEF2C,CTSV,CD276,DISC1,ARAP1,DAB2,TFEB
2.100e-02-3.86rhabdomyosarcomaCOSMIC cancer mutationsrhabdomyosarcoma4150181682846 RHBDF1,ETV6,CD276,FNIP1,ABCA1,ABCC5,RGL1,DAB2,DIAPH2,SH3KBP1,AOX1,SH2B3,FMNL1,DOCK4,ARAP3,ETS1,CEBPB,MLKL
2.105e-02-3.86diffuse_large_B_cell_lymphomaCOSMIC cancer mutationsdiffuse_large_B_cell_lymphoma4151181682846 BAZ2B,MAN1A1,FLRT2,HCK,ETV6,ATP8A1,MEF2C,FNIP1,SRGN,ARAP3,ETS1,MLKL,MICAL2,DIAPH2,ARHGEF1,SH3KBP1,BLNK,CD53
2.108e-02-3.86TAF1B (TATA-box binding protein associated factor, RNA polymerase I subunit B)protein interactions90148721945450 FERMT3,RXRA
2.108e-02-3.86GK (glycerol kinase)protein interactions27108721945450 RXRA,AOX1
2.108e-02-3.86PLCG2 (phospholipase C gamma 2)protein interactions53368721945450 HCK,BLNK
2.127e-02-3.85CD44 (CD44 molecule (IN blood group))protein interactions96023031945450 FMNL1,ARHGEF1,SRGN
2.127e-02-3.85developmental processbiological processGO:00325025716231820450 MEF2C,TFEB,SRGN,ADGRG3,RBM47,MARK4,CERT1,BLNK,SH2B3,FNIP1,CSF3R,HCK,MICAL2,PLEK,ELF4,DIAPH2,DAB2,DISC1,FLRT2,ETS1,RXRA,CEBPB,ETV6
2.127e-02-3.85positive regulation of metabolic processbiological processGO:00098933796171820450 CTSV,MEF2C,PLEK,MICAL2,ELF4,DAB2,TFEB,ARAP1,CD276,DISC1,ETS1,RBM47,FNIP1,RXRA,BLNK,ETV6,CEBPB
2.138e-02-3.85mesotheliomaCOSMIC cancer mutationsmesothelioma4477191682846 MAN1A1,MARK4,SGMS1,HCK,ETV6,MEF2C,FNIP1,TFEB,SH2B3,ELF4,MLKL,ARAP3,CEBPB,ETS1,RGL1,DAB2,DIAPH2,ARHGEF1,SH3KBP1
2.140e-02-3.84bMERB_dominterpro domainsIPR022735811852150 MICAL2
2.140e-02-3.84Peptidase_C1A_papain-likeinterpro domainsIPR039417811852150 CTSV
2.140e-02-3.84Myosin_TH1interpro domainsIPR010926811852150 MYO1F
2.175e-02-3.83Nicotine Metabolism PathwaySMPDB pathwaysSMP00006286113695 AOX1
2.177e-02-3.83regulation of Cdc42 protein signal transductionbiological processGO:0032489811820450 ABCA1
2.177e-02-3.83cardiac ventricle formationbiological processGO:0003211811820450 MEF2C
2.177e-02-3.83regulation of aldosterone biosynthetic processbiological processGO:0032347811820450 DAB2
2.177e-02-3.83regulation of aldosterone metabolic processbiological processGO:0032344811820450 DAB2
2.177e-02-3.83positive regulation of fear responsebiological processGO:1903367811820450 MEF2C
2.177e-02-3.83regulation of germinal center formationbiological processGO:0002634811820450 MEF2C
2.177e-02-3.83regulation of pro-B cell differentiationbiological processGO:2000973811820450 FNIP1
2.177e-02-3.83granzyme-mediated programmed cell death signaling pathwaybiological processGO:0140507811820450 SRGN
2.177e-02-3.83necroptotic signaling pathwaybiological processGO:0097527811820450 MLKL
2.182e-02-3.83RNGMNOXGNASEprints domainsPR0042051522723 MICAL2
2.182e-02-3.83MADSDOMAINprints domainsPR0040451522723 MEF2C
2.182e-02-3.82Myosin_TH1pfam domainsPF06017811779549 MYO1F
2.182e-02-3.82bMERB_dompfam domainsPF12130811779549 MICAL2
2.184e-02-3.82positive regulation of B cell activationbiological processGO:00508718321820450 SH3KBP1,MEF2C
2.190e-02-3.82phosphatidylcholine floppase activitymolecular functionGO:0090554811809450 ABCA1
2.190e-02-3.82ceramide transfer activitymolecular functionGO:0120017811809450 CERT1
2.196e-02-3.82FAD_PCMHprosite domainsPS51387611218645 AOX1
2.196e-02-3.822FE2S_FER_2prosite domainsPS51085611218645 AOX1
2.199e-02-3.82SLC25A41 (solute carrier family 25 member 41)protein interactions2844278921945450 DAB2,FCHO2
2.212e-02-3.81RHOJ (ras homolog family member J)protein interactions5738162851945450 DIAPH2,FCHO2,FMNL1,FLRT2,ABCC5
2.214e-02-3.81EndocytosisKEGG pathwaysko041442604716130 ARAP3,ARAP1,SH3KBP1,DAB2
2.214e-02-3.81EndocytosisKEGG pathwayshsa041442604716130 DAB2,SH3KBP1,ARAP1,ARAP3
2.219e-02-3.81Signaling mediated by p38-alpha and p38-betaPathway Interaction DBp38alphabetadownstreampathway352222615 CEBPB,MEF2C
2.224e-02-3.81SEC24B (SEC24 homolog B, COPII coat complex component)protein interactions1042723431945450 DAB2,MAN1A1,GLDC
2.241e-02-3.80large_intestine-colonCOSMIC cancer mutationslarge_intestine-colon129181682846 MAN1A1,STAB1,ABCA1,FLRT2,ETV6,MICAL2,ABCC5,MEF2C
2.262e-02-3.79soft_tissueCOSMIC cancer mutationssoft_tissue5828231682846 ABCC5,RGL1,DIAPH2,DAB2,SH3KBP1,BLNK,AOX1,SH2B3,ARAP3,DOCK4,FMNL1,ETS1,CEBPB,MLKL,RHBDF1,ETV6,ATP8A1,GLDC,FNIP1,CD276,BAZ2B,ABCA1,PLEK
2.272e-02-3.78human chr3q25.32chromosome locationhuman chr3q25.321212613450 MFSD1
2.273e-02-3.78embryonalCOSMIC cancer mutationsembryonal2659131682846 FNIP1,RHBDF1,ETV6,ABCA1,SH3KBP1,ABCC5,DIAPH2,DAB2,FMNL1,DOCK4,ETS1,CEBPB,SH2B3
2.273e-02-3.78soft_tissue-striated_muscle-rhabdomyosarcoma-embryonalCOSMIC cancer mutationssoft_tissue-striated_muscle-rhabdomyosarcoma-embryonal2659131682846 RHBDF1,ETV6,FNIP1,ABCA1,DAB2,DIAPH2,ABCC5,SH3KBP1,SH2B3,FMNL1,DOCK4,CEBPB,ETS1
2.274e-02-3.78positive regulation of cell migrationbiological processGO:003033559251820450 ETS1,DAB2,DOCK4,ATP8A1,FERMT3
2.283e-02-3.78embryonic heart tube developmentbiological processGO:00350508521820450 MICAL2,MEF2C
2.289e-02-3.78supramolecular fiber organizationbiological processGO:009743559351820450 DIAPH2,SH3KBP1,MYO1F,MICAL2,ARAP1
2.290e-02-3.78PCNX4 (pecanex 4)protein interactions64430911945450 DISC1
2.290e-02-3.78RTKN2 (rhotekin 2)protein interactions219790911945450 SH3KBP1
2.290e-02-3.78PPFIA4 (PTPRF interacting protein alpha 4)protein interactions8497911945450 DISC1
2.290e-02-3.78SEMA3A (semaphorin 3A)protein interactions10371911945450 DISC1
2.290e-02-3.78CHI3L2 (chitinase 3 like 2)protein interactions1117911945450 ETS1
2.290e-02-3.78ALG14 (ALG14 UDP-N-acetylglucosaminyltransferase subunit)protein interactions199857911945450 CD53
2.290e-02-3.78RBM46 (RNA binding motif protein 46)protein interactions166863911945450 RBM47
2.292e-02-3.78SOS1 (SOS Ras/Rac guanine nucleotide exchange factor 1)protein interactions66549121945450 HCK,SH3KBP1
2.292e-02-3.78TRIO (trio Rho guanine nucleotide exchange factor)protein interactions72049121945450 DAB2,DISC1
2.299e-02-3.77CAMK2A (calcium/calmodulin dependent protein kinase II alpha)protein interactions81523731945450 CEBPB,RBM47,ETS1
2.313e-02-3.77nicotine degradation IIIBIOCYC pathwaysHUMAN_PWY66-221719023 AOX1
2.313e-02-3.77sphingomyelin metabolism/ceramide salvageBIOCYC pathwaysHUMAN_PWY3DJ-11281719023 SGMS1
2.324e-02-3.76TAF6 (TATA-box binding protein associated factor 6)protein interactions687823831945450 ELF4,SH3KBP1,ETS1
2.324e-02-3.76CDC16 (cell division cycle 16)protein interactions888123831945450 SH3KBP1,DISC1,DAB2
2.331e-02-3.76chromaffin granule membranecellular componentGO:0042584911910850 ATP8A1
2.331e-02-3.76blebcellular componentGO:0032059911910850 FMNL1
2.331e-02-3.76presynaptic endocytic zonecellular componentGO:0098833911910850 FCHO2
2.331e-02-3.76unconventional myosin complexcellular componentGO:0016461911910850 MYO1F
2.334e-02-3.76vascular transportbiological processGO:00102328621820450 ATP8A1,ABCC5
2.334e-02-3.76transport across blood-brain barrierbiological processGO:01501048621820450 ATP8A1,ABCC5
2.350e-02-3.75Effects of Nitric OxideWikiPathwaysWP199571531018 AOX1
2.370e-02-3.74platelet alpha granulecellular componentGO:00310919121910850 SRGN,FERMT3
2.378e-02-3.74negative regulation of intracellular signal transductionbiological processGO:190253259951820450 ADGRG3,FNIP1,SH2B3,PLEK,DAB2
2.384e-02-3.74embryonic placenta developmentbiological processGO:00018928721820450 TFEB,CEBPB
2.387e-02-3.74ARHGAP17 (Rho GTPase activating protein 17)protein interactions551149321945450 SH3KBP1,FMNL1
2.387e-02-3.74MPDZ (multiple PDZ domain crumbs cell polarity complex component)protein interactions87779321945450 ABCA1,GLDC
2.387e-02-3.74ATF4 (activating transcription factor 4)protein interactions4689321945450 DISC1,CEBPB
2.404e-02-3.73Peptidase_S54_rhomboid_dominterpro domainsIPR022764911852150 RHBDF1
2.411e-02-3.73localizationbiological processGO:00511794474191820450 CD68,PLEK,ATP8A1,MYO1F,RHBDF1,MAN1A1,DAB2,TFEB,FCHO2,ABCC5,DISC1,MFSD1,SRGN,CERT1,STAB1,ARAP3,HCK,SH3KBP1,ABCA1
2.434e-02-3.72storiform_pleomorphicCOSMIC cancer mutationsstoriform_pleomorphic911682846 ETV6
2.434e-02-3.72soft_tissue-fibrous_tissue_and_uncertain_origin-malignant_fibrous_histiocytoma-pleomorphic_sarcoma-storiform_pleomorphicCOSMIC cancer mutationssoft_tissue-fibrous_tissue_and_uncertain_origin-malignant_fibrous_histiocytoma-pleomorphic_sarcoma-storiform_pleomorphic911682846 ETV6
2.435e-02-3.72KANSL1 (KAT8 regulatory NSL complex subunit 1)protein interactions2840589421945450 DISC1,ELF4
2.439e-02-3.71regulation of proteolysisbiological processGO:003016260351820450 FNIP1,DISC1,RHBDF1,CTSV,DAB2
2.441e-02-3.71response to endoplasmic reticulum stressbiological processGO:003497622731820450 CERT1,CEBPB,MAN1A1
2.446e-02-3.71positive regulation of Wnt signaling pathway, planar cell polarity pathwaybiological processGO:2000096911820450 DAB2
2.446e-02-3.71positive regulation of hormone biosynthetic processbiological processGO:0046886911820450 DAB2
2.446e-02-3.71negative regulation of antigen processing and presentationbiological processGO:0002578911820450 CD68
2.446e-02-3.71negative regulation of chemokine-mediated signaling pathwaybiological processGO:0070100911820450 SH2B3
2.446e-02-3.71tripeptide transmembrane transportbiological processGO:0035443911820450 ABCC5
2.446e-02-3.71positive regulation of early endosome to late endosome transportbiological processGO:2000643911820450 DAB2
2.446e-02-3.71glomerulus morphogenesisbiological processGO:0072102911820450 MEF2C
2.446e-02-3.71positive regulation of myeloid cell apoptotic processbiological processGO:0033034911820450 MEF2C
2.446e-02-3.71glutathione transportbiological processGO:0034635911820450 ABCC5
2.446e-02-3.71respiratory burst involved in defense responsebiological processGO:0002679911820450 HCK
2.446e-02-3.71liver morphogenesisbiological processGO:0072576911820450 CEBPB
2.446e-02-3.71heme transportbiological processGO:0015886911820450 ABCC5
2.446e-02-3.71aminophospholipid transportbiological processGO:0015917911820450 ATP8A1
2.446e-02-3.71antibacterial innate immune responsebiological processGO:0140367911820450 TFEB
2.446e-02-3.71peroxisome proliferator activated receptor signaling pathwaybiological processGO:0035357911820450 RXRA
2.446e-02-3.71regulation of vascular associated smooth muscle contractionbiological processGO:0003056911820450 DOCK4
2.452e-02-3.71Rhomboidpfam domainsPF01694911779549 RHBDF1
2.452e-02-3.71MBDpfam domainsPF01429911779549 BAZ2B
2.459e-02-3.71human chr4p13chromosome locationhuman chr4p131312613450 ATP8A1
2.459e-02-3.71human chr11p15.3chromosome locationhuman chr11p15.31312613450 MICAL2
2.460e-02-3.70sphingolipid transfer activitymolecular functionGO:0120016911809450 CERT1
2.460e-02-3.70heme transmembrane transporter activitymolecular functionGO:0015232911809450 ABCC5
2.460e-02-3.70NAD(P)H oxidase H2O2-forming activitymolecular functionGO:0016174911809450 MICAL2
2.460e-02-3.70mannosyl-oligosaccharide mannosidase activitymolecular functionGO:0015924911809450 MAN1A1
2.460e-02-3.70angiotensin receptor bindingmolecular functionGO:0031701911809450 ARAP1
2.463e-02-3.70flavin adenine dinucleotide bindingmolecular functionGO:00506608821809450 MICAL2,AOX1
2.471e-02-3.70macromolecule localizationbiological processGO:00330362376121820450 ABCA1,CERT1,DAB2,FCHO2,SRGN,MFSD1,DISC1,CD68,ATP8A1,PLEK,RHBDF1,MAN1A1
2.487e-02-3.69regulation of leukocyte apoptotic processbiological processGO:20001068921820450 MEF2C,FNIP1
2.488e-02-3.69N-glycan precursor trimmingKEGG pathwayshsa_M0007361716130 MAN1A1
2.488e-02-3.69Vitamin B6 metabolismKEGG pathwayshsa0075061716130 AOX1
2.488e-02-3.69Vitamin B6 metabolismKEGG pathwaysko0075061716130 AOX1
2.488e-02-3.69N-glycan precursor trimmingKEGG pathwaysM0007361716130 MAN1A1
2.496e-02-3.69regulation of proteolysis involved in protein catabolic processbiological processGO:190305022931820450 DISC1,RHBDF1,DAB2
2.507e-02-3.69guanyl-nucleotide exchange factor activitymolecular functionGO:000508522831809450 RGL1,DOCK4,ARHGEF1
2.519e-02-3.68striated_muscleCOSMIC cancer mutationsstriated_muscle4228181682846 MLKL,ETS1,CEBPB,ARAP3,FMNL1,DOCK4,SH2B3,AOX1,SH3KBP1,DIAPH2,DAB2,RGL1,ABCC5,ABCA1,CD276,FNIP1,ETV6,RHBDF1
2.525e-02-3.68focal adhesioncellular componentGO:000592542741910850 SH3KBP1,HCK,DAB2,FLRT2
2.527e-02-3.68Arfaptin homology (AH) domain/BAR domaingene3d domains1.20.1270.607621447047 FCHO2,ARHGAP45
2.532e-02-3.68TRIM35 (tripartite motif containing 35)protein interactions230879621945450 ARAP3,MYO1F
2.532e-02-3.68SMARCD3 (SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3)protein interactions66049621945450 ETS1,RXRA
2.532e-02-3.68RPRM (reprimo, TP53 dependent G2 arrest mediator homolog)protein interactions564759621945450 CD53,ADGRG3
2.534e-02-3.68Citalopram Metabolism PathwaySMPDB pathwaysSMP00006277113695 AOX1
2.541e-02-3.67PLA2G1B (phospholipase A2 group IB)protein interactions53191011945450 CSF3R
2.541e-02-3.67MACC1 (MET transcriptional regulator MACC1)protein interactions3463891011945450 FCHO2
2.541e-02-3.67Cltc (clathrin heavy chain)protein interactions673001011945450 SH3KBP1
2.541e-02-3.67PRTG (protogenin)protein interactions2836591011945450 DISC1
2.541e-02-3.67ARHGAP27 (Rho GTPase activating protein 27)protein interactions2011761011945450 SH3KBP1
2.541e-02-3.67CYGB (cytoglobin)protein interactions1147571011945450 SH3KBP1
2.541e-02-3.67AOX1 (aldehyde oxidase 1)protein interactions3161011945450 ABCA1
2.541e-02-3.67METTL26 (methyltransferase like 26)protein interactions843261011945450 DISC1
2.541e-02-3.67LSMEM1 (leucine rich single-pass membrane protein 1)protein interactions2860061011945450 CD53
2.541e-02-3.67RASGEF1B (RasGEF domain family member 1B)protein interactions1530201011945450 BAZ2B
2.553e-02-3.67cellular response to nutrient levelsbiological processGO:003166923131820450 TFEB,CD68,FNIP1
2.557e-02-3.67HEMATOPO_REC_L_F2prosite domainsPS01353711218645 CSF3R
2.558e-02-3.67PICALM (phosphatidylinositol binding clathrin assembly protein)protein interactions830124731945450 FCHO2,DAB2,RBM47
2.561e-02-3.66enzyme regulator activitymolecular functionGO:0030234130581809450 FNIP1,ARAP3,CTSV,ARAP1,ARHGEF1,DOCK4,ARHGAP45,RGL1
2.570e-02-3.66Kinase associated domain 1, KA1gene3d domains3.30.310.80811447047 MARK4
2.581e-02-3.66CBLB (Cbl proto-oncogene B)protein interactions8689721945450 SH3KBP1,BLNK
2.581e-02-3.66SOCS3 (suppressor of cytokine signaling 3)protein interactions90219721945450 ETV6,CSF3R
2.585e-02-3.66KAT2B (lysine acetyltransferase 2B)protein interactions885024831945450 ELF4,ETS1,CEBPB
2.585e-02-3.66MET (MET proto-oncogene, receptor tyrosine kinase)protein interactions423324831945450 HCK,SH3KBP1,SH2B3
2.587e-02-3.65Golgi trans cisternacellular componentGO:00001381011910850 SGMS1
2.592e-02-3.65regulation of smooth muscle cell migrationbiological processGO:00149109121820450 DOCK4,MEF2C
2.595e-02-3.65haematopoietic_and_lymphoid_tissue-haematopoietic_neoplasm-myelofibrosisCOSMIC cancer mutationshaematopoietic_and_lymphoid_tissue-haematopoietic_neoplasm-myelofibrosis41341682846 DIAPH2,SH2B3,CSF3R,ETS1
2.595e-02-3.65myelofibrosisCOSMIC cancer mutationsmyelofibrosis41341682846 ETS1,CSF3R,SH2B3,DIAPH2
2.631e-02-3.64WDCP (WD repeat and coiled coil containing)protein interactions803049821945450 ETV6,HCK
2.644e-02-3.63RHOQ (ras homolog family member Q)protein interactions2343344141945450 FCHO2,DIAPH2,ABCC5,FLRT2
2.646e-02-3.63human chr14q31.3chromosome locationhuman chr14q31.31412613450 FLRT2
2.648e-02-3.63cell junctioncellular componentGO:00300542224111910850 ATP8A1,FCHO2,FERMT3,SH3KBP1,HCK,CD53,MEF2C,FLRT2,MLKL,DISC1,DAB2
2.649e-02-3.63chromatincellular componentGO:0000785138781910850 ETS1,TFEB,MEF2C,RXRA,CEBPB,BAZ2B,ELF4,ETV6
2.666e-02-3.62TGFBR1 (transforming growth factor beta receptor 1)protein interactions704625131945450 DAB2,SH3KBP1,PLEK
2.668e-02-3.62Pept_asp_ASinterpro domainsIPR0256611011852150 CTSV
2.680e-02-3.62Flnb (filamin, beta)protein interactions2869409921945450 DAB2,FCHO2
2.682e-02-3.62Folate-Alcohol and Cancer PathwayWikiPathwaysWP158981531018 CEBPB
2.693e-02-3.61positive regulation of cell motilitybiological processGO:200014761951820450 DAB2,DOCK4,ATP8A1,ETS1,FERMT3
2.693e-02-3.61NCK2 (NCK adaptor protein 2)protein interactions844025231945450 DISC1,ARAP1,BLNK
2.701e-02-3.61NK_cell_leukaemiaCOSMIC cancer mutationsNK_cell_leukaemia1011682846 CSF3R
2.701e-02-3.61lung-carcinoma-blastomaCOSMIC cancer mutationslung-carcinoma-blastoma1011682846 ETV6
2.701e-02-3.61haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-NK_cell_leukaemiaCOSMIC cancer mutationshaematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-NK_cell_leukaemia1011682846 CSF3R
2.706e-02-3.61Inhibitor_I29smart domainsSM0084871971738 CTSV
2.714e-02-3.61cellular response to parathyroid hormone stimulusbiological processGO:00713741011820450 MEF2C
2.714e-02-3.61thrombin-activated receptor signaling pathwaybiological processGO:00704931011820450 PLEK
2.714e-02-3.61regulation of behavioral fear responsebiological processGO:20008221011820450 MEF2C
2.714e-02-3.61folic acid transportbiological processGO:00158841011820450 ABCC5
2.714e-02-3.61germinal center formationbiological processGO:00024671011820450 MEF2C
2.714e-02-3.61regulation of odontoblast differentiationbiological processGO:19013291011820450 CEBPB
2.714e-02-3.61high-density lipoprotein particle assemblybiological processGO:00343801011820450 ABCA1
2.714e-02-3.61regulation of vitamin D receptor signaling pathwaybiological processGO:00705621011820450 RXRA
2.714e-02-3.61integrin activationbiological processGO:00336221011820450 FERMT3
2.715e-02-3.61haematopoietic_and_lymphoid_tissueCOSMIC cancer mutationshaematopoietic_and_lymphoid_tissue14368441682846 MAN1A1,MARK4,ARAP1,STAB1,SGMS1,FERMT3,ETV6,CD276,MFSD1,ATP8A1,TFEB,SRGN,AOX1,CD68,CSF3R,ETS1,FMNL1,DOCK4,DIAPH2,DAB2,RGL1,MICAL2,ABCC5,SH3KBP1,BAZ2B,HCK,PLEK,FLRT2,ABCA1,RHBDF1,FNIP1,GLDC,MEF2C,FCHO2,RBM47,SH2B3,ELF4,RXRA,MLKL,ARAP3,MYO1F,CD53,BLNK,ARHGEF1
2.717e-02-3.61MYH9 (myosin heavy chain 9)protein interactions462766351945450 FCHO2,DAB2,MARK4,GLDC,RXRA
2.721e-02-3.60MED23 (mediator complex subunit 23)protein interactions943925331945450 RXRA,ETS1,CEBPB
2.727e-02-3.60regulation of lymphocyte proliferationbiological processGO:005067023731820450 MEF2C,CEBPB,CD276
2.729e-02-3.60protein dimerization activitymolecular functionGO:0046983107471809450 MEF2C,TFEB,PLEK,CEBPB,MFSD1,AOX1,GLDC
2.730e-02-3.60ATPase-coupled inorganic anion transmembrane transporter activitymolecular functionGO:00432251011809450 ABCC5
2.730e-02-3.60minor groove of adenine-thymine-rich DNA bindingmolecular functionGO:00036801011809450 MEF2C
2.731e-02-3.60AP2S1 (adaptor related protein complex 2 subunit sigma 1)protein interactions117510021945450 FCHO2,ARHGEF1
2.731e-02-3.60REPS1 (RALBP1 associated Eps domain containing 1)protein interactions8502110021945450 DAB2,RXRA
2.738e-02-3.60cellular response to chemical stimulusbiological processGO:00708872411121820450 DOCK4,ABCC5,CD68,MEF2C,GLDC,CSF3R,AOX1,CEBPB,HCK,ABCA1,RXRA,SH2B3
2.781e-02-3.58PRKCG (protein kinase C gamma)protein interactions558210121945450 MARK4,DAB2
2.792e-02-3.58Fcho2 (FCH domain only 2)protein interactions2185031111945450 DAB2
2.792e-02-3.58BIVM (basic, immunoglobulin-like variable motif containing)protein interactions548411111945450 BAZ2B
2.792e-02-3.58RUBCNL (rubicon like autophagy enhancer)protein interactions801831111945450 CERT1
2.792e-02-3.58CD302 (CD302 molecule)protein interactions99361111945450 CD53
2.792e-02-3.58MEF2B (myocyte enhancer factor 2B)protein interactions1002718491111945450 MEF2C
2.792e-02-3.58CCDC141 (coiled-coil domain containing 141)protein interactions2850251111945450 DISC1
2.809e-02-3.57enzyme-linked receptor protein signaling pathwaybiological processGO:000716762651820450 FLRT2,SH2B3,BLNK,HCK,DAB2
2.815e-02-3.57Circadian ClockREACTOME pathwaysR-HSA-4002537121028538 MEF2C,RXRA
2.832e-02-3.56FASLG (Fas ligand)protein interactions35610221945450 HCK,DOCK4
2.832e-02-3.56PATJ (PATJ crumbs cell polarity complex component)protein interactions1020710221945450 GLDC,SH3KBP1
2.832e-02-3.56TMPRSS13 (transmembrane serine protease 13)protein interactions8400010221945450 CTSV,MAN1A1
2.853e-02-3.56bone-femur-Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumourCOSMIC cancer mutationsbone-femur-Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour63351682846 ELF4,STAB1,BAZ2B,ABCA1,GLDC
2.860e-02-3.55UBAP2L (ubiquitin associated protein 2 like)protein interactions989825831945450 GLDC,RBM47,DISC1
2.875e-02-3.55ruffle membranecellular componentGO:003258710121910850 ARHGAP45,PLEK
2.876e-02-3.55regulation of mononuclear cell proliferationbiological processGO:003294424231820450 MEF2C,CEBPB,CD276
2.879e-02-3.55FLOT1 (flotillin 1)protein interactions1021145341945450 ETV6,ELF4,ABCA1,DISC1
2.886e-02-3.55prostateCOSMIC cancer mutationsprostate13883431682846 DAB2,DIAPH2,MICAL2,ABCC5,ETS1,DOCK4,AOX1,CD276,ATP8A1,ETV6,MAN1A1,MARK4,STAB1,SGMS1,CD53,ARAP3,RBM47,ELF4,RXRA,MEF2C,GLDC,HCK,PLEK,FLRT2,ABCA1,BAZ2B,SH3KBP1,RGL1,CSF3R,FMNL1,TFEB,SRGN,FERMT3,ARAP1,BLNK,ARHGEF1,MYO1F,MLKL,SH2B3,FNIP1,FCHO2,DISC1,RHBDF1
2.889e-02-3.54MARK2 (microtubule affinity regulating kinase 2)protein interactions201125931945450 CERT1,GLDC,MARK4
2.902e-02-3.54regulation of hemopoiesisbiological processGO:190370642541820450 CSF3R,CEBPB,ETS1,MEF2C
2.906e-02-3.54HNRNPK (heterogeneous nuclear ribonucleoprotein K)protein interactions319067551945450 MARK4,GLDC,CEBPB,HCK,SH3KBP1
2.906e-02-3.54anatomical structure developmentbiological processGO:00488565207211820450 SRGN,FLRT2,ADGRG3,DISC1,TFEB,DAB2,DIAPH2,MEF2C,MICAL2,PLEK,CEBPB,ETV6,HCK,CSF3R,FNIP1,SH2B3,BLNK,RXRA,CERT1,MARK4,RBM47
2.917e-02-3.53ceramide metabolic processbiological processGO:00066729721820450 SGMS1,CERT1
2.917e-02-3.53leukocyte homeostasisbiological processGO:00017769721820450 MEF2C,SH2B3
2.917e-02-3.53TH1prosite domainsPS51757811218645 MYO1F
2.917e-02-3.53BMERBprosite domainsPS51848811218645 MICAL2
2.919e-02-3.53Axonal growth inhibition (RHOA activation)REACTOME pathwaysR-HSA-193634811028538 ARHGEF1
2.919e-02-3.53Nef and signal transductionREACTOME pathwaysR-HSA-164944811028538 HCK
2.920e-02-3.53LCK (LCK proto-oncogene, Src family tyrosine kinase)protein interactions393245541945450 CSF3R,SH2B3,HCK,SH3KBP1
2.928e-02-3.53positive regulation of locomotionbiological processGO:004001763351820450 ETS1,DAB2,DOCK4,ATP8A1,FERMT3
2.931e-02-3.53DOCKER_Lobe_Binterpro domainsIPR0467701111852150 DOCK4
2.931e-02-3.53Methyl_CpG_DNA-bdinterpro domainsIPR0017391111852150 BAZ2B
2.931e-02-3.53DOCKinterpro domainsIPR0267911111852150 DOCK4
2.931e-02-3.53Pept_his_ASinterpro domainsIPR0256601111852150 CTSV
2.931e-02-3.53DOCKER_Lobe_Cinterpro domainsIPR0467731111852150 DOCK4
2.931e-02-3.53DOCKER_Lobe_Ainterpro domainsIPR0467691111852150 DOCK4
2.931e-02-3.53DNA-bd_dom_sfinterpro domainsIPR0161771111852150 BAZ2B
2.931e-02-3.53C2_DOCK-type_domaininterpro domainsIPR0270071111852150 DOCK4
2.931e-02-3.53DOCK_C_lobe_Cinterpro domainsIPR0431621111852150 DOCK4
2.931e-02-3.53DOCK_C_lobe_Ainterpro domainsIPR0431611111852150 DOCK4
2.931e-02-3.53DOCKER_dominterpro domainsIPR0273571111852150 DOCK4
2.952e-02-3.52anchoring junctioncellular componentGO:007016190261910850 DAB2,HCK,CD53,SH3KBP1,FERMT3,FLRT2
2.968e-02-3.52regulation of inflammatory responsebiological processGO:005072742841820450 HCK,CEBPB,ETS1,ELF4
2.968e-02-3.52cell surface receptor protein tyrosine kinase signaling pathwaybiological processGO:000716942841820450 FLRT2,SH2B3,BLNK,HCK
2.981e-02-3.51cardiac chamber formationbiological processGO:00032071111820450 MEF2C
2.981e-02-3.51regulation of dendritic cell antigen processing and presentationbiological processGO:00026041111820450 CD68
2.981e-02-3.51positive regulation of cardiac muscle cell differentiationbiological processGO:20007271111820450 MEF2C
2.981e-02-3.51response to glycoproteinbiological processGO:19045871111820450 MAN1A1
2.981e-02-3.51secondary heart field specificationbiological processGO:00031391111820450 MEF2C
2.981e-02-3.51regulation of macrophage apoptotic processbiological processGO:20001091111820450 MEF2C
2.981e-02-3.51positive regulation of steroid hormone secretionbiological processGO:20008331111820450 DAB2
2.981e-02-3.51cyclic nucleotide transportbiological processGO:00707291111820450 ABCC5
2.981e-02-3.51negative regulation of platelet aggregationbiological processGO:00903311111820450 SH2B3
2.981e-02-3.51positive regulation of integrin activationbiological processGO:00336251111820450 PLEK
2.981e-02-3.51negative regulation of cholesterol storagebiological processGO:00108871111820450 ABCA1
2.981e-02-3.51tripeptide transportbiological processGO:00429391111820450 ABCC5
2.981e-02-3.51pyramidal neuron developmentbiological processGO:00218601111820450 DISC1
2.981e-02-3.51regulation of fear responsebiological processGO:19033651111820450 MEF2C
2.981e-02-3.51regulation of cell-cell adhesion mediated by integrinbiological processGO:00336321111820450 FERMT3
2.981e-02-3.51guanine nucleotide transportbiological processGO:00014081111820450 ABCC5
2.981e-02-3.51sphingomyelin biosynthetic processbiological processGO:00066861111820450 SGMS1
2.987e-02-3.51Class I PI3K signaling eventsPathway Interaction DBpi3kcipathway412222615 HCK,ARAP3
2.988e-02-3.51bZIP_2pfam domainsPF077161111779549 CEBPB
2.988e-02-3.51DHR-2_Lobe_Apfam domainsPF069201111779549 DOCK4
2.988e-02-3.51DOCK-C2pfam domainsPF144291111779549 DOCK4
2.988e-02-3.51DHR-2_Lobe_Cpfam domainsPF204211111779549 DOCK4
2.988e-02-3.51LRRCTpfam domainsPF014631111779549 FLRT2
2.988e-02-3.51DHR-2_Lobe_Bpfam domainsPF204221111779549 DOCK4
2.990e-02-3.51response to xenobiotic stimulusbiological processGO:000941042941820450 ABCA1,ABCC5,AOX1,MEF2C
2.990e-02-3.51superficial_spreadingCOSMIC cancer mutationssuperficial_spreading111071682846 ATP8A1,DIAPH2,FLRT2,ABCA1,STAB1,ARAP1,AOX1
2.999e-02-3.51glycine bindingmolecular functionGO:00165941111809450 GLDC
2.999e-02-3.51GTPase activating protein bindingmolecular functionGO:00327941111809450 FMNL1
2.999e-02-3.51oligopeptide transmembrane transporter activitymolecular functionGO:00356731111809450 ABCC5
2.999e-02-3.51regulation of synapse organizationbiological processGO:005080724631820450 MEF2C,FLRT2,DISC1
3.018e-02-3.50human chrXp22.12chromosome locationhuman chrXp22.121612613450 SH3KBP1
3.030e-02-3.50humoral immune responsebiological processGO:000695924731820450 BLNK,MEF2C,TFEB
3.039e-02-3.49Lipoprotein metabolismREACTOME pathwaysR-HSA-1748247421028538 ABCA1,SH3KBP1
3.042e-02-3.49GLYHDRLASE47prints domainsPR0074771522723 MAN1A1
3.042e-02-3.49NUDT4 (nudix hydrolase 4)protein interactions111631211945450 DISC1
3.042e-02-3.49TM7SF2 (transmembrane 7 superfamily member 2)protein interactions71081211945450 DISC1
3.042e-02-3.49C8orf76 (chromosome 8 open reading frame 76)protein interactions849331211945450 DISC1
3.042e-02-3.49ROBO4 (roundabout guidance receptor 4)protein interactions545381211945450 RXRA
3.042e-02-3.49TLDC2 (TBC/LysM-associated domain containing 2)protein interactions1407111211945450 GLDC
3.042e-02-3.49PNMT (phenylethanolamine N-methyltransferase)protein interactions54091211945450 HCK
3.042e-02-3.49SOWAHB (sosondowah ankyrin repeat domain family member B)protein interactions3450791211945450 DIAPH2
3.087e-02-3.48DUF3585smart domainsSM0120381971738 MICAL2
3.100e-02-3.47RHOA (ras homolog family member A)protein interactions387118671945450 DIAPH2,DAB2,FMNL1,FLRT2,ARHGEF1,ABCC5,SGMS1
3.104e-02-3.47regulation of cellular component organizationbiological processGO:00511282455121820450 PLEK,ATP8A1,MEF2C,MARK4,FNIP1,CD53,ARAP1,DAB2,HCK,DISC1,ABCA1,FLRT2
3.113e-02-3.47response to other organismbiological processGO:0051707136381820450 MLKL,MEF2C,CD68,ABCA1,HCK,CEBPB,STAB1,TFEB
3.114e-02-3.47testis-germ_cell_tumour-seminomaCOSMIC cancer mutationstestis-germ_cell_tumour-seminoma64851682846 STAB1,MARK4,FLRT2,MLKL,HCK
3.121e-02-3.47RANGAP1 (Ran GTPase activating protein 1)protein interactions590526731945450 DISC1,CERT1,GLDC
3.121e-02-3.47DNM2 (dynamin 2)protein interactions178526731945450 HCK,SH3KBP1,ARHGEF1
3.142e-02-3.46platelet activationbiological processGO:003016810121820450 PLEK,FERMT3
3.147e-02-3.46TRADD (TNFRSF1A associated via death domain)protein interactions871710821945450 RXRA,SH3KBP1
3.147e-02-3.46PHF12 (PHD finger protein 12)protein interactions5764910821945450 ETS1,ELF4
3.149e-02-3.46response to external biotic stimulusbiological processGO:0043207136681820450 HCK,CEBPB,TFEB,STAB1,ABCA1,MEF2C,CD68,MLKL
3.150e-02-3.46stomach-carcinomaCOSMIC cancer mutationsstomach-carcinoma43941682846 CSF3R,MLKL,HCK,MARK4
3.160e-02-3.45clear_cell_renal_cell_carcinomaCOSMIC cancer mutationsclear_cell_renal_cell_carcinoma13924431682846 MLKL,MYO1F,BLNK,ARHGEF1,RHBDF1,FNIP1,DISC1,FCHO2,TFEB,SRGN,FMNL1,CEBPB,CSF3R,RGL1,SH3KBP1,ARAP1,FERMT3,MFSD1,RBM47,RXRA,ELF4,ARAP3,CD53,BAZ2B,PLEK,FLRT2,HCK,ABCA1,MEF2C,GLDC,AOX1,DOCK4,ETS1,DIAPH2,DAB2,ABCC5,MICAL2,STAB1,MARK4,MAN1A1,SGMS1,ETV6,ATP8A1
3.160e-02-3.45kidney-carcinoma-clear_cell_renal_cell_carcinomaCOSMIC cancer mutationskidney-carcinoma-clear_cell_renal_cell_carcinoma13924431682846 TFEB,SRGN,CSF3R,CEBPB,FMNL1,RGL1,SH3KBP1,ARAP1,FERMT3,MFSD1,MLKL,MYO1F,BLNK,ARHGEF1,RHBDF1,FNIP1,FCHO2,DISC1,AOX1,ETS1,DOCK4,DIAPH2,DAB2,MICAL2,ABCC5,MARK4,MAN1A1,STAB1,SGMS1,ETV6,ATP8A1,RBM47,ELF4,RXRA,ARAP3,CD53,BAZ2B,HCK,FLRT2,PLEK,ABCA1,GLDC,MEF2C
3.161e-02-3.45actin bindingmolecular functionGO:000377943441809450 MYO1F,MICAL2,DIAPH2,FMNL1
3.181e-02-3.45regulation of response to external stimulusbiological processGO:0032101111671820450 SH2B3,ELF4,MARK4,HCK,CEBPB,ETS1,RBM47
3.189e-02-3.45regulation of synapse structure or activitybiological processGO:005080325231820450 FLRT2,DISC1,MEF2C
3.193e-02-3.44ABCAinterpro domainsIPR0260821211852150 ABCA1
3.200e-02-3.44SIPA1L3 (signal induced proliferation associated 1 like 3)protein interactions2309410921945450 GLDC,FMNL1
3.202e-02-3.44Rhomboid-likegene3d domains1.20.1540.101011447047 RHBDF1
3.225e-02-3.43Neutrophil degranulationREACTOME pathwaysR-HSA-679869548751028538 ATP8A1,CD53,ARHGAP45,ADGRG3,CD68
3.232e-02-3.43bone-sacrum-Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumourCOSMIC cancer mutationsbone-sacrum-Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour1211682846 STAB1
3.232e-02-3.43blastomaCOSMIC cancer mutationsblastoma1211682846 ETV6
3.232e-02-3.43central_nervous_system-cerebellum-other-gangliogliomaCOSMIC cancer mutationscentral_nervous_system-cerebellum-other-ganglioglioma1211682846 ETV6
3.232e-02-3.43desmoid_tumour-fibromatosisCOSMIC cancer mutationsdesmoid_tumour-fibromatosis1211682846 ETV6
3.232e-02-3.43soft_tissue-fibrous_tissue_and_uncertain_origin-desmoid_tumour-fibromatosisCOSMIC cancer mutationssoft_tissue-fibrous_tissue_and_uncertain_origin-desmoid_tumour-fibromatosis1211682846 ETV6
3.248e-02-3.43iron coordination entity transportbiological processGO:19016781211820450 ABCC5
3.248e-02-3.43B cell apoptotic processbiological processGO:00017831211820450 FNIP1
3.248e-02-3.43mesenchymal cell apoptotic processbiological processGO:00971521211820450 ETV6
3.248e-02-3.43negative regulation of vasoconstrictionbiological processGO:00459061211820450 DOCK4
3.248e-02-3.43heart field specificationbiological processGO:00031281211820450 MEF2C
3.248e-02-3.43regulation of protein localization to centrosomebiological processGO:19047791211820450 MARK4
3.248e-02-3.43oligopeptide transmembrane transportbiological processGO:00356721211820450 ABCC5
3.248e-02-3.43actin filament depolymerizationbiological processGO:00300421211820450 MICAL2
3.248e-02-3.43regulation of lysosome organizationbiological processGO:19056711211820450 FNIP1
3.248e-02-3.43immature B cell differentiationbiological processGO:00023271211820450 FNIP1
3.248e-02-3.43cytidine to uridine editingbiological processGO:00165541211820450 RBM47
3.248e-02-3.43regulation of lymphoid progenitor cell differentiationbiological processGO:19054561211820450 FNIP1
3.248e-02-3.43serine family amino acid catabolic processbiological processGO:00090711211820450 GLDC
3.248e-02-3.43regulation of chemokine-mediated signaling pathwaybiological processGO:00700991211820450 SH2B3
3.248e-02-3.43cellular response to antibioticbiological processGO:00712361211820450 MEF2C
3.248e-02-3.43negative regulation of smooth muscle contractionbiological processGO:00459861211820450 DOCK4
3.256e-02-3.42ABC2_membrane_3pfam domainsPF126981211779549 ABCA1
3.264e-02-3.42IL6-mediated signaling eventsPathway Interaction DBil6_7pathway432222615 CEBPB,HCK
3.278e-02-3.42PTK6 Regulates RTKs and Their Effectors AKT1 and DOK1REACTOME pathwaysR-HSA-8849469911028538 ARAP1
3.278e-02-3.42Formation of annular gap junctionsREACTOME pathwaysR-HSA-196025911028538 DAB2
3.278e-02-3.42p75NTR regulates axonogenesisREACTOME pathwaysR-HSA-193697911028538 ARHGEF1
3.291e-02-3.41Kif20b (kinesin family member 20B)protein interactions2406411311945450 DIAPH2
3.291e-02-3.41IL2 (interleukin 2)protein interactions35581311945450 CD53
3.291e-02-3.41Septin2 (septin 2)protein interactions180001311945450 SH3KBP1
3.291e-02-3.41KCTD20 (potassium channel tetramerization domain containing 20)protein interactions2226581311945450 MARK4
3.291e-02-3.41MYBPC3 (myosin binding protein C3)protein interactions46071311945450 BLNK
3.291e-02-3.41CRYGC (crystallin gamma C)protein interactions14201311945450 DISC1
3.291e-02-3.41C1orf74 (chromosome 1 open reading frame 74)protein interactions1483041311945450 HCK
3.291e-02-3.41SERTM1 (serine rich and transmembrane domain containing 1)protein interactions4001201311945450 CD53
3.293e-02-3.41nicotine degradation IVBIOCYC pathwaysHUMAN_PWY66-2011019023 AOX1
3.302e-02-3.41FLOT2 (flotillin 2)protein interactions231927331945450 ELF4,ETV6,DISC1
3.315e-02-3.41positive regulation of ubiquitin-dependent protein catabolic processbiological processGO:200006010421820450 DISC1,DAB2
3.315e-02-3.41lytic vacuole organizationbiological processGO:008017110421820450 TFEB,ABCA1
3.315e-02-3.41regulation of dephosphorylationbiological processGO:003530310421820450 MEF2C,PLEK
3.315e-02-3.41lysosome organizationbiological processGO:000704010421820450 ABCA1,TFEB
3.322e-02-3.40protein domain specific bindingmolecular functionGO:001990465151809450 ETV6,DOCK4,RXRA,BLNK,SH3KBP1
3.341e-02-3.40Liver X Receptor PathwayWikiPathwaysWP2874101531018 RXRA
3.341e-02-3.40Vitamin D MetabolismWikiPathwaysWP1531101531018 RXRA
3.353e-02-3.40Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumourCOSMIC cancer mutationsEwings_sarcoma-peripheral_primitive_neuroectodermal_tumour7434271682846 ARAP1,STAB1,MARK4,MFSD1,ETV6,DOCK4,FMNL1,CSF3R,CD68,AOX1,SH3KBP1,ABCC5,MICAL2,DAB2,ABCA1,FLRT2,HCK,BAZ2B,MEF2C,GLDC,FNIP1,RHBDF1,MLKL,ELF4,ARHGEF1,BLNK,MYO1F
3.363e-02-3.39NFRKB (nuclear factor related to kappaB binding protein)protein interactions479811221945450 ETS1,ELF4
3.363e-02-3.39MYO18A (myosin XVIIIA)protein interactions39968727531945450 DAB2,GLDC,MARK4
3.381e-02-3.39positive regulation of developmental processbiological processGO:0051094138581820450 DAB2,CEBPB,DISC1,FLRT2,ETS1,MEF2C,RXRA,CD53
3.384e-02-3.39small GTPase-mediated signal transductionbiological processGO:000726425831820450 DOCK4,ARHGEF1,RGL1
3.385e-02-3.39protein-DNA complexcellular componentGO:0032993145481910850 MEF2C,ELF4,ETV6,CEBPB,RXRA,BAZ2B,ETS1,TFEB
3.394e-02-3.38FLII (FLII actin remodeling protein)protein interactions231427631945450 DISC1,FMNL1,GLDC
3.418e-02-3.38RBM6 (RNA binding motif protein 6)protein interactions1018011321945450 DISC1,GLDC
3.432e-02-3.37response to retinoic acidbiological processGO:003252610621820450 RXRA,ABCA1
3.432e-02-3.37regulation of actin filament bundle assemblybiological processGO:003223110621820450 ARAP1,PLEK
3.447e-02-3.37SH3_1pfam domainsPF0001810621779549 MYO1F,HCK
3.454e-02-3.37Peptidase_C1Ainterpro domainsIPR0131281311852150 CTSV
3.454e-02-3.37Peptidase_C1A_Cinterpro domainsIPR0006681311852150 CTSV
3.457e-02-3.36TJP2 (tight junction protein 2)protein interactions941427831945450 GLDC,DISC1,SH3KBP1
3.457e-02-3.36bone-humerus-Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumourCOSMIC cancer mutationsbone-humerus-Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour10721682846 ABCA1,GLDC
3.472e-02-3.36response to stressbiological processGO:00069503388151820450 TFEB,FERMT3,CD68,PLEK,MEF2C,MAN1A1,STAB1,CSF3R,CEBPB,HCK,ABCA1,CERT1,BLNK,FNIP1,MLKL
3.474e-02-3.36ACVR1 (activin A receptor type 1)protein interactions9011421945450 PLEK,RXRA
3.514e-02-3.35response to parathyroid hormonebiological processGO:00711071311820450 MEF2C
3.514e-02-3.35type II interferon-mediated signaling pathwaybiological processGO:00603331311820450 HCK
3.514e-02-3.35negative regulation of homotypic cell-cell adhesionbiological processGO:00341111311820450 SH2B3
3.514e-02-3.35positive regulation of actin filament depolymerizationbiological processGO:00308361311820450 PLEK
3.514e-02-3.35positive regulation of platelet activationbiological processGO:00105721311820450 PLEK
3.514e-02-3.35phospholipid effluxbiological processGO:00337001311820450 ABCA1
3.517e-02-3.35-gene3d domains1.25.40.4101111447047 DOCK4
3.517e-02-3.35-gene3d domains1.20.58.7401111447047 DOCK4
3.520e-02-3.35TSG101 (tumor susceptibility 101)protein interactions725128031945450 HCK,SH3KBP1,MLKL
3.522e-02-3.35Peptidase_C1pfam domainsPF001121311779549 CTSV
3.535e-02-3.34high-density lipoprotein particle bindingmolecular functionGO:00080351311809450 ABCA1
3.535e-02-3.34glycerophospholipid flippase activitymolecular functionGO:01403331311809450 ATP8A1
3.540e-02-3.34PLA2G12A (phospholipase A2 group XIIA)protein interactions815791411945450 MEF2C
3.540e-02-3.34PALMD (palmdelphin)protein interactions548731411945450 SH3KBP1
3.540e-02-3.34Asap1 (ArfGAP with SH3 domain, ankyrin repeat and PH domain1)protein interactions131961411945450 SH3KBP1
3.540e-02-3.34CSF3 (colony stimulating factor 3)protein interactions14401411945450 CSF3R
3.540e-02-3.34LINC02872 (long intergenic non-protein coding RNA 2872)protein interactions4015351411945450 GLDC
3.540e-02-3.34BORCS8-MEF2B (BORCS8-MEF2B readthrough)protein interactions42071411945450 MEF2C
3.540e-02-3.34Septin7 (septin 7)protein interactions2350721411945450 SH3KBP1
3.540e-02-3.34TFEC (transcription factor EC)protein interactions227971411945450 TFEB
3.546e-02-3.34stomach-carcinoma-diffuse_adenocarcinomaCOSMIC cancer mutationsstomach-carcinoma-diffuse_adenocarcinoma4383181682846 MICAL2,RGL1,MYO1F,DIAPH2,ARHGEF1,BLNK,RXRA,SH2B3,RBM47,FMNL1,DOCK4,FERMT3,ATP8A1,BAZ2B,STAB1,MAN1A1,ABCA1,FLRT2
3.546e-02-3.34diffuse_adenocarcinomaCOSMIC cancer mutationsdiffuse_adenocarcinoma4383181682846 MICAL2,RGL1,DIAPH2,MYO1F,ARHGEF1,BLNK,RXRA,SH2B3,RBM47,DOCK4,FMNL1,FERMT3,ATP8A1,STAB1,BAZ2B,MAN1A1,ABCA1,FLRT2
3.551e-02-3.34Thromboxane A2 receptor signalingPathway Interaction DBtxa2pathway452222615 HCK,ARHGEF1
3.551e-02-3.34SKP2 (S-phase kinase associated protein 2)protein interactions650228131945450 DISC1,MEF2C,ELF4
3.574e-02-3.33human chrXq26.1chromosome locationhuman chrXq26.11912613450 ELF4
3.576e-02-3.33LAMTOR1 (late endosomal/lysosomal adaptor, MAPK and MTOR activator 1)protein interactions5500471451945450 ATP8A1,ABCC5,FCHO2,DAB2,DIAPH2
3.578e-02-3.33breast-carcinomaCOSMIC cancer mutationsbreast-carcinoma15030451682846 CSF3R,FMNL1,SRGN,CD68,TFEB,SH3KBP1,RGL1,ARAP1,MFSD1,FERMT3,MLKL,SH2B3,ARHGEF1,BLNK,MYO1F,FCHO2,DISC1,FNIP1,RHBDF1,ETS1,DOCK4,AOX1,MICAL2,ABCC5,DAB2,DIAPH2,SGMS1,MAN1A1,MARK4,STAB1,ATP8A1,CD276,ETV6,ARAP3,ELF4,RXRA,RBM47,CD53,ABCA1,HCK,FLRT2,PLEK,BAZ2B,MEF2C,GLDC
3.586e-02-3.33GGA1 (golgi associated, gamma adaptin ear containing, ARF binding protein 1)protein interactions2608811621945450 STAB1,ETS1
3.593e-02-3.33positive regulation of DNA-templated transcriptionbiological processGO:0045893166791820450 TFEB,DAB2,ETV6,CEBPB,ELF4,RXRA,MICAL2,ETS1,MEF2C
3.603e-02-3.32phospholipid-translocating ATPase complexcellular componentGO:19905311411910850 ATP8A1
3.603e-02-3.32cytolytic granulecellular componentGO:00441941411910850 SRGN
3.603e-02-3.32chromaffin granulecellular componentGO:00425831411910850 ATP8A1
3.629e-02-3.32positive regulation of RNA biosynthetic processbiological processGO:1902680167091820450 TFEB,DAB2,CEBPB,ETV6,RXRA,ELF4,MICAL2,MEF2C,ETS1
3.633e-02-3.32THIOL_PROTEASE_ASNprosite domainsPS006401011218645 CTSV
3.635e-02-3.31Gap junction degradationREACTOME pathwaysR-HSA-1908731011028538 DAB2
3.677e-02-3.30response to biotic stimulusbiological processGO:0009607140881820450 STAB1,TFEB,HCK,CEBPB,ABCA1,CD68,MEF2C,MLKL
3.680e-02-3.30ATXN2 (ataxin 2)protein interactions631128531945450 GLDC,RBM47,SH3KBP1
3.699e-02-3.30BCL7A (BAF chromatin remodeling complex subunit BCL7A)protein interactions60511821945450 ETS1,ELF4
3.699e-02-3.30B4GALT2 (beta-1,4-galactosyltransferase 2)protein interactions870411821945450 ETV6,ARAP3
3.704e-02-3.30Golgi cisternacellular componentGO:003198511621910850 ARAP1,SGMS1
3.715e-02-3.29Beta-grasp_dom_sfinterpro domainsIPR0126751411852150 AOX1
3.715e-02-3.29MHDinterpro domainsIPR0285651411852150 FCHO2
3.715e-02-3.29P-type_ATPase_Ninterpro domainsIPR0326311411852150 ATP8A1
3.715e-02-3.29P_typ_ATPase_cinterpro domainsIPR0326301411852150 ATP8A1
3.715e-02-3.29Rhomboid-like_sfinterpro domainsIPR0359521411852150 RHBDF1
3.715e-02-3.29P-type_ATPase_IVinterpro domainsIPR0065391411852150 ATP8A1
3.715e-02-3.29Ras_G-nucl-exch_fac_CSinterpro domainsIPR0198041411852150 RGL1
3.715e-02-3.29Link_dominterpro domainsIPR0005381411852150 STAB1
3.724e-02-3.29regulation of leukocyte proliferationbiological processGO:007066326831820450 CD276,MEF2C,CEBPB
3.733e-02-3.29negative regulation of bindingbiological processGO:005110011121820450 DAB2,DISC1
3.744e-02-3.29protein localizationbiological processGO:00081041954101820450 DAB2,FCHO2,DISC1,MFSD1,SRGN,ABCA1,CD68,PLEK,RHBDF1,MAN1A1
3.745e-02-3.28HSPA1B (heat shock protein family A (Hsp70) member 1B)protein interactions330428731945450 FNIP1,DAB2,FMNL1
3.754e-02-3.28nasopharyngeal_carcinomaCOSMIC cancer mutationsnasopharyngeal_carcinoma142581682846 RHBDF1,ABCC5,FNIP1,SH2B3,STAB1,MARK4,MLKL,FLRT2
3.754e-02-3.28upper_aerodigestive_tract-pharynx-carcinoma-nasopharyngeal_carcinomaCOSMIC cancer mutationsupper_aerodigestive_tract-pharynx-carcinoma-nasopharyngeal_carcinoma142581682846 ABCC5,RHBDF1,FNIP1,STAB1,SH2B3,MARK4,FLRT2,MLKL
3.755e-02-3.28MAPK1 (mitogen-activated protein kinase 1)protein interactions559449341945450 ARHGAP45,RXRA,ETS1,CEBPB
3.759e-02-3.28regulation of actin filament organizationbiological processGO:011005326931820450 ARAP1,PLEK,HCK
3.777e-02-3.28MAP4 (microtubule associated protein 4)protein interactions413428831945450 MARK4,GLDC,SH3KBP1
3.779e-02-3.28positive regulation of phospholipid transportbiological processGO:20011401411820450 ATP8A1
3.779e-02-3.28mammary gland epithelial cell proliferationbiological processGO:00335981411820450 CEBPB
3.779e-02-3.28negative regulation of macrophage derived foam cell differentiationbiological processGO:00107451411820450 ABCA1
3.779e-02-3.28ventricular cardiac muscle cell differentiationbiological processGO:00550121411820450 MEF2C
3.779e-02-3.28oligopeptide transportbiological processGO:00068571411820450 ABCC5
3.779e-02-3.28positive regulation of receptor recyclingbiological processGO:00019211411820450 ARAP1
3.779e-02-3.28alpha-beta T cell proliferationbiological processGO:00466331411820450 ELF4
3.779e-02-3.28regulation of podosome assemblybiological processGO:00718011411820450 HCK
3.779e-02-3.28cellular response to oxidised low-density lipoprotein particle stimulusbiological processGO:01400521411820450 CD68
3.788e-02-3.27GCK (glucokinase)protein interactions26451511945450 CSF3R
3.788e-02-3.27TIAM2 (TIAM Rac1 associated GEF 2)protein interactions262301511945450 DISC1
3.788e-02-3.27ASCL4 (achaete-scute family bHLH transcription factor 4)protein interactions1215491511945450 ARAP3
3.788e-02-3.27UCP3 (uncoupling protein 3)protein interactions73521511945450 RBM47
3.788e-02-3.27CASTOR1 (cytosolic arginine sensor for mTORC1 subunit 1)protein interactions6529681511945450 RXRA
3.788e-02-3.27LRRC24 (leucine rich repeat containing 24)protein interactions4413811511945450 MAN1A1
3.788e-02-3.27Xlinkpfam domainsPF001931411779549 STAB1
3.788e-02-3.27PhoLip_ATPase_Cpfam domainsPF162121411779549 ATP8A1
3.788e-02-3.27PhoLip_ATPase_Npfam domainsPF162091411779549 ATP8A1
3.801e-02-3.27ABC-type xenobiotic transporter activitymolecular functionGO:00085591411809450 ABCC5
3.801e-02-3.27alpha-mannosidase activitymolecular functionGO:00045591411809450 MAN1A1
3.814e-02-3.27FRS3 (fibroblast growth factor receptor substrate 3)protein interactions1081712021945450 HCK,SH3KBP1
3.814e-02-3.27SRCAP (Snf2 related CREBBP activator protein)protein interactions1084712021945450 ETS1,ELF4
3.814e-02-3.27LIMD1 (LIM domain containing 1)protein interactions899412021945450 ETV6,DISC1
3.836e-02-3.26cellular macromolecule localizationbiological processGO:00707271962101820450 RHBDF1,MAN1A1,CD68,PLEK,DISC1,MFSD1,ABCA1,SRGN,DAB2,FCHO2
3.838e-02-3.26negative regulation of transcription by RNA polymerase IIbiological processGO:000012291561820450 RXRA,FNIP1,DAB2,ETV6,MEF2C,CEBPB
3.856e-02-3.26positive regulation of plasma membrane bounded cell projection assemblybiological processGO:012003411321820450 MARK4,ARAP1
3.863e-02-3.25skin-head_neck-malignant_melanoma-superficial_spreadingCOSMIC cancer mutationsskin-head_neck-malignant_melanoma-superficial_spreading92361682846 ATP8A1,STAB1,ARAP1,AOX1,FLRT2,ABCA1
3.899e-02-3.24signaling adaptor activitymolecular functionGO:003559111321809450 SH2B3,BLNK
3.900e-02-3.24vascular process in circulatory systembiological processGO:000301827331820450 ATP8A1,DOCK4,ABCC5
3.910e-02-3.24NFKB1 (nuclear factor kappa B subunit 1)protein interactions479029231945450 ETS1,RXRA,CEBPB
3.922e-02-3.24prostate-carcinomaCOSMIC cancer mutationsprostate-carcinoma9000311682846 GLDC,MEF2C,FNIP1,RHBDF1,ABCA1,HCK,BAZ2B,ARHGEF1,BLNK,MYO1F,ARAP3,RXRA,ELF4,RBM47,ATP8A1,CD276,ETV6,FERMT3,SGMS1,STAB1,MAN1A1,SH3KBP1,ABCC5,MICAL2,RGL1,DAB2,DIAPH2,ETS1,CSF3R,AOX1,TFEB
3.929e-02-3.24SH2DOMAINprints domainsPR00401722522723 SH2B3,HCK
3.930e-02-3.24OGA (O-GlcNAcase)protein interactions1072412221945450 CEBPB,ARHGEF1
3.959e-02-3.23Ammonia RecyclingSMPDB pathwaysSMP000000911113695 GLDC
3.961e-02-3.23transcription coregulator bindingmolecular functionGO:000122111421809450 RXRA,ETS1
3.975e-02-3.23START_lipid-bd_dominterpro domainsIPR0029131511852150 CERT1
3.985e-02-3.22fibrous_tissue_and_uncertain_originCOSMIC cancer mutationsfibrous_tissue_and_uncertain_origin27731682846 ABCC5,ETV6,BAZ2B
3.988e-02-3.22GABPA (GA binding protein transcription factor subunit alpha)protein interactions255112321945450 CTSV,ELF4
3.989e-02-3.22DOCKERprosite domainsPS516511111218645 DOCK4
3.989e-02-3.22MBDprosite domainsPS509821111218645 BAZ2B
3.989e-02-3.22C2_DOCKprosite domainsPS516501111218645 DOCK4
3.989e-02-3.22THIOL_PROTEASE_HISprosite domainsPS006391111218645 CTSV
3.991e-02-3.22regulation of response to stressbiological processGO:0080134143181820450 ELF4,SH2B3,RBM47,MARK4,MEF2C,ETS1,HCK,CEBPB
3.991e-02-3.22defense responsebiological processGO:0006952143181820450 CD68,MLKL,BLNK,HCK,CEBPB,CSF3R,STAB1,TFEB
3.992e-02-3.22Import of palmitoyl-CoA into the mitochondrial matrixREACTOME pathwaysR-HSA-2004251111028538 RXRA
3.994e-02-3.22chondrosarcomaCOSMIC cancer mutationschondrosarcoma118171682846 DAB2,RBM47,BLNK,CSF3R,ABCA1,ATP8A1,DOCK4
4.011e-02-3.22RUNX1 (RUNX family transcription factor 1)protein interactions86129531945450 CEBPB,FERMT3,ELF4
4.024e-02-3.21soft_tissue-fibrous_tissue_and_uncertain_origin-synovial_sarcoma-biphasicCOSMIC cancer mutationssoft_tissue-fibrous_tissue_and_uncertain_origin-synovial_sarcoma-biphasic1511682846 ETV6
4.024e-02-3.21monophasicCOSMIC cancer mutationsmonophasic1511682846 ETV6
4.024e-02-3.21soft_tissue-nerve_sheath-neurofibromaCOSMIC cancer mutationssoft_tissue-nerve_sheath-neurofibroma1511682846 ETV6
4.024e-02-3.21soft_tissue-fibrous_tissue_and_uncertain_origin-synovial_sarcoma-monophasicCOSMIC cancer mutationssoft_tissue-fibrous_tissue_and_uncertain_origin-synovial_sarcoma-monophasic1511682846 ETV6
4.035e-02-3.21IL1RL2 (interleukin 1 receptor like 2)protein interactions88081611945450 MYO1F
4.035e-02-3.21DEFB106A (defensin beta 106A)protein interactions2459091611945450 CTSV
4.035e-02-3.21AKAP6 (A-kinase anchoring protein 6)protein interactions94721611945450 DISC1
4.035e-02-3.21EPO (erythropoietin)protein interactions20561611945450 MAN1A1
4.035e-02-3.21NUDT6 (nudix hydrolase 6)protein interactions111621611945450 GLDC
4.035e-02-3.21GPNMB (glycoprotein nmb)protein interactions104571611945450 TFEB
4.035e-02-3.21CTSK (cathepsin K)protein interactions15131611945450 CTSV
4.035e-02-3.21Clspn (claspin)protein interactions2695821611945450 FNIP1
4.035e-02-3.21CASTOR2 (cytosolic arginine sensor for mTORC1 subunit 2)protein interactions7294381611945450 RXRA
4.035e-02-3.21CAPN6 (calpain 6)protein interactions8271611945450 GLDC
4.035e-02-3.21TWIST2 (twist family bHLH transcription factor 2)protein interactions1175811611945450 MEF2C
4.035e-02-3.21ZSCAN4 (zinc finger and SCAN domain containing 4)protein interactions2015161611945450 HCK
4.043e-02-3.21response to laminar fluid shear stressbiological processGO:00346161511820450 ABCA1
4.043e-02-3.21positive regulation of hormone metabolic processbiological processGO:00323521511820450 DAB2
4.043e-02-3.21regulation of phospholipid transportbiological processGO:20011381511820450 ATP8A1
4.043e-02-3.21regulation of dendritic cell differentiationbiological processGO:20011981511820450 CEBPB
4.043e-02-3.21protein homotrimerizationbiological processGO:00702071511820450 MLKL
4.043e-02-3.21regulation of inositol phosphate biosynthetic processbiological processGO:00109191511820450 PLEK
4.043e-02-3.21actin filament severingbiological processGO:00510141511820450 FMNL1
4.043e-02-3.21positive regulation of non-canonical Wnt signaling pathwaybiological processGO:20000521511820450 DAB2
4.043e-02-3.21negative regulation of androgen receptor signaling pathwaybiological processGO:00607661511820450 DAB2
4.043e-02-3.21cytoplasm organizationbiological processGO:00070281511820450 ETV6
4.043e-02-3.21protein deglycosylationbiological processGO:00065171511820450 MAN1A1
4.043e-02-3.21positive regulation of myoblast fusionbiological processGO:19017411511820450 CD53
4.043e-02-3.21pyramidal neuron differentiationbiological processGO:00218591511820450 DISC1
4.043e-02-3.21regulation of steroid hormone biosynthetic processbiological processGO:00900301511820450 DAB2
4.047e-02-3.21DAB2 (DAB adaptor protein 2)protein interactions160112421945450 SH3KBP1,FCHO2
4.053e-02-3.21STARTpfam domainsPF018521511779549 CERT1
4.067e-02-3.20fatCOSMIC cancer mutationsfat11721682846 ETV6,ARAP3
4.067e-02-3.20low-density lipoprotein particle receptor activitymolecular functionGO:00050411511809450 STAB1
4.067e-02-3.20mannosidase activitymolecular functionGO:00159231511809450 MAN1A1
4.067e-02-3.20efflux transmembrane transporter activitymolecular functionGO:00155621511809450 ABCC5
4.067e-02-3.20nuclear vitamin D receptor bindingmolecular functionGO:00428091511809450 RXRA
4.068e-02-3.20phosphatidylinositol bindingmolecular functionGO:003509127631809450 ARAP3,ARAP1,FCHO2
4.107e-02-3.19regulation of synapse assemblybiological processGO:005196311721820450 FLRT2,MEF2C
4.131e-02-3.19seminomaCOSMIC cancer mutationsseminoma70051682846 MLKL,FLRT2,HCK,STAB1,MARK4
4.144e-02-3.18RHOH (ras homolog family member H)protein interactions39950941945450 FLRT2,ABCC5,DAB2,FMNL1
4.156e-02-3.18SAMsmart domainsSM00454832971738 ARAP1,ARAP3
4.166e-02-3.18RNF115 (ring finger protein 115)protein interactions2724612621945450 DOCK4,CTSV
4.170e-02-3.18Transcriptional regulation of white adipocyte differentiationREACTOME pathwaysR-HSA-3813408821028538 RXRA,CEBPB
4.195e-02-3.17positive regulation of cellular metabolic processbiological processGO:00313253164141820450 CEBPB,ETV6,ETS1,RBM47,FNIP1,RXRA,BLNK,TFEB,DAB2,CD276,MEF2C,MICAL2,PLEK,ELF4
4.221e-02-3.17MBDsmart domainsSM00391111971738 BAZ2B
4.233e-02-3.16RNA polymerase II cis-regulatory region sequence-specific DNA bindingmolecular functionGO:0000978118071809450 MEF2C,ETS1,CEBPB,ETV6,ELF4,TFEB,RXRA
4.248e-02-3.16haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-chronic_lymphocytic_leukaemia-small_lymphocytic_lymphomaCOSMIC cancer mutationshaematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-chronic_lymphocytic_leukaemia-small_lymphocytic_lymphoma3511151682846 ARHGEF1,DIAPH2,DAB2,ARAP3,FMNL1,DOCK4,CSF3R,TFEB,RBM47,ELF4,MFSD1,ETV6,FLRT2,HCK,BAZ2B
4.248e-02-3.16chronic_lymphocytic_leukaemia-small_lymphocytic_lymphomaCOSMIC cancer mutationschronic_lymphocytic_leukaemia-small_lymphocytic_lymphoma3511151682846 FLRT2,HCK,BAZ2B,MFSD1,ETV6,ARAP3,FMNL1,DOCK4,CSF3R,ELF4,RBM47,TFEB,ARHGEF1,DAB2,DIAPH2
4.282e-02-3.15IL31 (interleukin 31)protein interactions3866531711945450 MAN1A1
4.282e-02-3.15SPATA13 (spermatogenesis associated 13)protein interactions2211781711945450 GLDC
4.282e-02-3.15OLFM1 (olfactomedin 1)protein interactions104391711945450 DISC1
4.282e-02-3.15Tsg101 (tumor susceptibility gene 101)protein interactions220881711945450 SH3KBP1
4.282e-02-3.15AFD1 (acrofacial dysostosis 1, Nager type)protein interactions1711711945450 GLDC
4.282e-02-3.15ALKBH2 (alkB homolog 2, alpha-ketoglutarate dependent dioxygenase)protein interactions1216421711945450 FERMT3
4.282e-02-3.15Abr (active BCR-related gene)protein interactions1099341711945450 DOCK4
4.282e-02-3.15ST6GAL2 (ST6 beta-galactoside alpha-2,6-sialyltransferase 2)protein interactions846201711945450 CD53
4.286e-02-3.15BTK (Bruton tyrosine kinase)protein interactions69512821945450 HCK,BLNK
4.286e-02-3.15ATF7IP (activating transcription factor 7 interacting protein)protein interactions5572912821945450 DISC1,ELF4
4.287e-02-3.15central_nervous_system-temporal_lobe-glioma-astrocytoma_Grade_IICOSMIC cancer mutationscentral_nervous_system-temporal_lobe-glioma-astrocytoma_Grade_II1611682846 FLRT2
4.287e-02-3.15renal_pelvisCOSMIC cancer mutationsrenal_pelvis1611682846 ETV6
4.307e-02-3.14regulation of corticosteroid hormone secretionbiological processGO:20008461611820450 DAB2
4.307e-02-3.14positive regulation of lymphocyte apoptotic processbiological processGO:00702301611820450 FNIP1
4.307e-02-3.14regulation of Wnt signaling pathway, planar cell polarity pathwaybiological processGO:20000951611820450 DAB2
4.307e-02-3.14xenobiotic transmembrane transportbiological processGO:00068551611820450 ABCC5
4.307e-02-3.14neutrophil homeostasisbiological processGO:00017801611820450 SH2B3
4.307e-02-3.14glycine metabolic processbiological processGO:00065441611820450 GLDC
4.323e-02-3.14SRF and miRs in Smooth Muscle Differentiation and ProliferationWikiPathwaysWP1991131531018 MEF2C
4.325e-02-3.14cell adhesionbiological processGO:000715594261820450 FLRT2,FERMT3,HCK,CSF3R,PLEK,STAB1
4.333e-02-3.14flippase activitymolecular functionGO:01403271611809450 ATP8A1
4.333e-02-3.14oxidoreductase activity, acting on NAD(P)H, oxygen as acceptormolecular functionGO:00506641611809450 MICAL2
4.343e-02-3.14Sphingolipid metabolismREACTOME pathwaysR-HSA-4281579021028538 CERT1,SGMS1
4.344e-02-3.14LINK_1prosite domainsPS012411211218645 STAB1
4.346e-02-3.14Lima1 (LIM domain and actin binding 1)protein interactions6597012921945450 FCHO2,DAB2
4.347e-02-3.14Endosomal/Vacuolar pathwayREACTOME pathwaysR-HSA-12369771211028538 CTSV
4.349e-02-3.14testis-germ_cell_tumour-non_seminomaCOSMIC cancer mutationstestis-germ_cell_tumour-non_seminoma48741682846 MLKL,FNIP1,HCK,MARK4
4.356e-02-3.13ATAD3A (ATPase family AAA domain containing 3A)protein interactions5521030531945450 GLDC,SH3KBP1,FMNL1
4.363e-02-3.13regulation of immune responsebiological processGO:005077694461820450 RBM47,HCK,MARK4,MEF2C,CD276,BLNK
4.379e-02-3.13export from cellbiological processGO:014035248541820450 ABCC5,HCK,PLEK,ABCA1
4.379e-02-3.13response to nutrient levelsbiological processGO:003166748541820450 ABCA1,FNIP1,TFEB,CD68
4.407e-02-3.12positive regulation of cell adhesionbiological processGO:004578548641820450 CD276,DISC1,ETS1,DAB2
4.445e-02-3.11follicular_lymphomaCOSMIC cancer mutationsfollicular_lymphoma120971682846 BAZ2B,DIAPH2,RXRA,FLRT2,HCK,ATP8A1,ABCA1
4.453e-02-3.11positive regulation of innate immune responsebiological processGO:004508928831820450 RBM47,MARK4,HCK
4.455e-02-3.11-gene3d domains3.10.20.301411447047 AOX1
4.468e-02-3.11GATAD1 (GATA zinc finger domain containing 1)protein interactions5779813121945450 ELF4,ETS1
4.468e-02-3.11NCOA2 (nuclear receptor coactivator 2)protein interactions1049913121945450 MEF2C,RXRA
4.475e-02-3.11positive regulation of macromolecule biosynthetic processbiological processGO:00105572592121820450 DAB2,TFEB,ETV6,CEBPB,CD276,MICAL2,RBM47,MEF2C,ETS1,ELF4,BLNK,RXRA
4.477e-02-3.11SH3 domain bindingmolecular functionGO:001712412221809450 SH3KBP1,DOCK4
4.487e-02-3.10non_seminomaCOSMIC cancer mutationsnon_seminoma49241682846 MARK4,FNIP1,HCK,MLKL
4.493e-02-3.10ABC2_TMinterpro domainsIPR0135251711852150 ABCA1
4.494e-02-3.10human chr11q24.3chromosome locationhuman chr11q24.32412613450 ETS1
4.529e-02-3.09KLF13 (KLF transcription factor 13)protein interactions516211811945450 SH3KBP1
4.529e-02-3.09ADO (2-aminoethanethiol dioxygenase)protein interactions848901811945450 DISC1
4.529e-02-3.09SRR (serine racemase)protein interactions638261811945450 DISC1
4.529e-02-3.09SPARCL1 (SPARC like 1)protein interactions84041811945450 DISC1
4.529e-02-3.09ACTL8 (actin like 8)protein interactions815691811945450 CERT1
4.529e-02-3.09ZNF365 (zinc finger protein 365)protein interactions228911811945450 DISC1
4.529e-02-3.09Tnks2 (tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2)protein interactions744931811945450 FMNL1
4.529e-02-3.09SLC13A2 (solute carrier family 13 member 2)protein interactions90581811945450 CERT1
4.529e-02-3.09ANKRD29 (ankyrin repeat domain 29)protein interactions1474631811945450 FERMT3
4.529e-02-3.09MVB12B (multivesicular body subunit 12B)protein interactions898531811945450 MLKL
4.530e-02-3.09lymphocyte differentiationbiological processGO:003009829031820450 BLNK,FNIP1,ADGRG3
4.549e-02-3.09neurofibromaCOSMIC cancer mutationsneurofibroma1711682846 ETV6
4.560e-02-3.09positive regulation of cell-substrate adhesionbiological processGO:001081112421820450 DISC1,DAB2
4.570e-02-3.09reverse cholesterol transportbiological processGO:00436911711820450 ABCA1
4.570e-02-3.09mammary gland epithelial cell differentiationbiological processGO:00606441711820450 CEBPB
4.570e-02-3.09iron ion transmembrane transportbiological processGO:00347551711820450 ABCC5
4.570e-02-3.09muscle cell fate commitmentbiological processGO:00426931711820450 MEF2C
4.570e-02-3.09nuclear body organizationbiological processGO:00305751711820450 ETS1
4.570e-02-3.09protein trimerizationbiological processGO:00702061711820450 MLKL
4.570e-02-3.09regulation of integrin activationbiological processGO:00336231711820450 PLEK
4.570e-02-3.09protein kinase C signalingbiological processGO:00705281711820450 PLEK
4.570e-02-3.09specification of animal organ identitybiological processGO:00100921711820450 MEF2C
4.570e-02-3.09phospholipid homeostasisbiological processGO:00550911711820450 ABCA1
4.591e-02-3.08PLAUR (plasminogen activator, urokinase receptor)protein interactions532913321945450 HCK,MAN1A1
4.597e-02-3.08low-density lipoprotein particle bindingmolecular functionGO:00301691711809450 STAB1
4.597e-02-3.08apolipoprotein bindingmolecular functionGO:00341851711809450 ABCA1
4.615e-02-3.08skin-malignant_melanomaCOSMIC cancer mutationsskin-malignant_melanoma15741461682846 SH2B3,MLKL,MYO1F,ARHGEF1,BLNK,RHBDF1,DISC1,FCHO2,FNIP1,CD68,SRGN,TFEB,FMNL1,CSF3R,CEBPB,RGL1,SH3KBP1,ARAP1,FERMT3,MFSD1,RXRA,ELF4,RBM47,ARAP3,CD53,BAZ2B,ABCA1,FLRT2,PLEK,HCK,GLDC,MEF2C,AOX1,DOCK4,ETS1,ABCC5,MICAL2,DAB2,DIAPH2,SGMS1,STAB1,MARK4,MAN1A1,ETV6,ATP8A1,CD276
4.620e-02-3.07cis-regulatory region sequence-specific DNA bindingmolecular functionGO:0000987120371809450 MEF2C,ETS1,ETV6,CEBPB,TFEB,ELF4,RXRA
4.636e-02-3.07lung-carcinoma-adenocarcinomaCOSMIC cancer mutationslung-carcinoma-adenocarcinoma15133451682846 RHBDF1,FNIP1,FCHO2,DISC1,MYO1F,BLNK,ARHGEF1,SH2B3,MLKL,FERMT3,MFSD1,ARAP1,RGL1,SH3KBP1,TFEB,SRGN,CSF3R,CEBPB,FMNL1,GLDC,MEF2C,BAZ2B,HCK,PLEK,FLRT2,ABCA1,CD53,RBM47,ELF4,RXRA,ARAP3,ETV6,CD276,ATP8A1,MARK4,MAN1A1,STAB1,SGMS1,DAB2,DIAPH2,MICAL2,ABCC5,AOX1,ETS1,DOCK4
4.643e-02-3.07protein homodimerization activitymolecular functionGO:004280371451809450 CEBPB,PLEK,GLDC,AOX1,MFSD1
4.653e-02-3.07ARL4C (ADP ribosylation factor like GTPase 4C)protein interactions1012313421945450 FLRT2,ABCC5
4.653e-02-3.07PHF10 (PHD finger protein 10)protein interactions5527413421945450 ETS1,ELF4
4.677e-02-3.06human chr7q31.1chromosome locationhuman chr7q31.12512613450 DOCK4
4.680e-02-3.06CORO1C (coronin 1C)protein interactions2360331431945450 GLDC,DISC1,FMNL1
4.680e-02-3.06HSF2BP (heat shock transcription factor 2 binding protein)protein interactions1107731431945450 HCK,ARHGAP45,BAZ2B
4.693e-02-3.06xenobiotic metabolic processbiological processGO:000680512621820450 ABCC5,AOX1
4.701e-02-3.06FCGR activationREACTOME pathwaysR-HSA-20294811311028538 HCK
4.716e-02-3.05Myo1c (myosin IC)protein interactions1791313521945450 FCHO2,DAB2
4.725e-02-3.05myeloid cell differentiationbiological processGO:003009929531820450 MEF2C,CEBPB,SH2B3
4.740e-02-3.05SPECTRNALPHAprints domainsPR01887111522723 SH3KBP1
4.740e-02-3.05PAPAINprints domainsPR00705111522723 CTSV
4.746e-02-3.05regulation of anatomical structure sizebiological processGO:009006649841820450 HCK,DOCK4,PLEK,DISC1
4.752e-02-3.05EGF_dominterpro domainsIPR0247311811852150 STAB1
4.757e-02-3.05bindingmolecular functionGO:000548816422491809450 GLDC,CD276,HCK,SH3KBP1,DISC1,MFSD1,CEBPB,FNIP1,STAB1,SH2B3,PLEK,MARK4,RBM47,CD53,MLKL,ARAP3,RHBDF1,MEF2C,MYO1F,RGL1,TFEB,ELF4,CTSV,ARAP1,DAB2,ABCC5,AOX1,ADGRG3,RXRA,BLNK,MAN1A1,ETS1,ARHGAP45,FCHO2,CD68,DIAPH2,ETV6,DOCK4,CERT1,ATP8A1,BAZ2B,CSF3R,MICAL2,FMNL1,FERMT3,SRGN,FLRT2,ARHGEF1,ABCA1
4.771e-02-3.04lung-carcinoid-endocrine_tumourCOSMIC cancer mutationslung-carcinoid-endocrine_tumour50241682846 MARK4,BAZ2B,HCK,MLKL
4.774e-02-3.04RIMS2 (regulating synaptic membrane exocytosis 2)protein interactions96991911945450 ABCA1
4.774e-02-3.04Capza1 (capping actin protein of muscle Z-line subunit alpha 1)protein interactions123401911945450 SH3KBP1
4.774e-02-3.04ZNF197 (zinc finger protein 197)protein interactions101681911945450 DISC1
4.774e-02-3.04RAP1BL (RAP1B like (pseudogene))protein interactions6437521911945450 CD53
4.774e-02-3.04RIT2 (Ras like without CAAX 2)protein interactions60141911945450 RGL1
4.774e-02-3.04CRYBB1 (crystallin beta B1)protein interactions14141911945450 DISC1
4.774e-02-3.04PARVB (parvin beta)protein interactions297801911945450 FERMT3
4.791e-02-3.04LGALS1 (galectin 1)protein interactions395631731945450 CD68,CD276,HCK
4.810e-02-3.03salivary_gland-carcinoma-acinic_cell_carcinomaCOSMIC cancer mutationssalivary_gland-carcinoma-acinic_cell_carcinoma1811682846 ETV6
4.827e-02-3.03regulation of protein bindingbiological processGO:004339312821820450 DAB2,DISC1
4.827e-02-3.03regulation of B cell activationbiological processGO:005086412821820450 SH3KBP1,MEF2C
4.832e-02-3.03heart formationbiological processGO:00609141811820450 MEF2C
4.832e-02-3.03retinoic acid receptor signaling pathwaybiological processGO:00483841811820450 RXRA
4.832e-02-3.03negative regulation of platelet activationbiological processGO:00105441811820450 SH2B3
4.832e-02-3.03positive regulation of cardiocyte differentiationbiological processGO:19052091811820450 MEF2C
4.832e-02-3.03ceramide transportbiological processGO:00356271811820450 CERT1
4.832e-02-3.03regulation of clathrin-dependent endocytosisbiological processGO:20003691811820450 DAB2
4.837e-02-3.03stomach-carcinoma-adenocarcinomaCOSMIC cancer mutationsstomach-carcinoma-adenocarcinoma15150451682846 FMNL1,CSF3R,CD68,SRGN,TFEB,SH3KBP1,RGL1,ARAP1,MFSD1,FERMT3,MLKL,SH2B3,ARHGEF1,BLNK,MYO1F,DISC1,FCHO2,FNIP1,RHBDF1,DOCK4,ETS1,AOX1,ABCC5,MICAL2,DAB2,DIAPH2,SGMS1,STAB1,MARK4,MAN1A1,ATP8A1,CD276,ETV6,ARAP3,RXRA,ELF4,RBM47,CD53,ABCA1,FLRT2,PLEK,HCK,BAZ2B,GLDC,MEF2C
4.842e-02-3.03CLUH (clustered mitochondria homolog)protein interactions2327713721945450 ARHGEF1,CEBPB
4.842e-02-3.03PUM2 (pumilio RNA binding family member 2)protein interactions2336913721945450 RBM47,GLDC
4.844e-02-3.03EGF_3pfam domainsPF129471811779549 STAB1
4.859e-02-3.02gamma-tubulin complexcellular componentGO:00009301911910850 MARK4
4.861e-02-3.02phosphatidylcholine transporter activitymolecular functionGO:00085251811809450 ABCA1
4.861e-02-3.02clathrin adaptor activitymolecular functionGO:00356151811809450 DAB2
4.861e-02-3.02lipoprotein particle receptor activitymolecular functionGO:00302281811809450 STAB1
4.865e-02-3.02UBXN6 (UBX domain protein 6)protein interactions8070031931945450 ARAP1,ARAP3,ARHGEF1
4.879e-02-3.02histone deacetylase bindingmolecular functionGO:004282612821809450 CEBPB,MEF2C
4.883e-02-3.02haematopoietic_neoplasmCOSMIC cancer mutationshaematopoietic_neoplasm11082361682846 SH3KBP1,DAB2,DIAPH2,RGL1,MICAL2,ABCC5,CSF3R,ETS1,DOCK4,AOX1,CD68,MFSD1,ATP8A1,ETV6,MAN1A1,MARK4,ARAP1,STAB1,SGMS1,BLNK,ARHGEF1,MYO1F,MLKL,SH2B3,ELF4,RXRA,FNIP1,GLDC,MEF2C,FCHO2,RHBDF1,HCK,FLRT2,PLEK,ABCA1,BAZ2B
4.905e-02-3.01AKAP12 (A-kinase anchoring protein 12)protein interactions959013821945450 HCK,SH3KBP1
4.905e-02-3.01NCOA1 (nuclear receptor coactivator 1)protein interactions864813821945450 ETS1,RXRA
4.940e-02-3.01ACTA1 (actin alpha 1, skeletal muscle)protein interactions5832131945450 MARK4,ARHGEF1,ETV6
4.951e-02-3.01regulation of lymphocyte activationbiological processGO:005124950541820450 CEBPB,MEF2C,CD276,SH3KBP1
4.962e-02-3.00lymphocyte proliferationbiological processGO:004665113021820450 MEF2C,ELF4
4.968e-02-3.00NEFM (neurofilament medium chain)protein interactions474113921945450 DISC1,GLDC
4.968e-02-3.00LARP1B (La ribonucleoprotein 1B)protein interactions5513213921945450 RBM47,GLDC
4.968e-02-3.00IFT20 (intraflagellar transport 20)protein interactions9041013921945450 DISC1,CERT1
4.968e-02-3.00LHFPL5 (LHFPL tetraspan subfamily member 5)protein interactions22266213921945450 ADGRG3,CD53
4.969e-02-3.00STARTsmart domainsSM00234131971738 CERT1
4.969e-02-3.00Pept_C1smart domainsSM00645131971738 CTSV
4.972e-02-3.00Transcriptional activation by NRF2WikiPathwaysWP3151531018 CEBPB
4.983e-02-3.00PK_Tyr_Ser-Thrpfam domainsPF0771413021779549 HCK,MLKL