P-value | ln(P) | Term | GO Tree | GO ID | # of Genes in Term | # of Target Genes in Term | # of Total Genes | # of Target Genes | Common Genes |
3.612e-22 | -49.37 | cytosolic ribosome | cellular component | GO:0022626 | 115 | 15 | 19108 | 50 |
RPS3A,RPL14,RPS20,RPS26,RPL18A,RPL35,RPL36A,RPS14,RPS25,RPL13A,RPL34,RPL8,RPL12,RPL27A,RPL37A |
2.998e-21 | -47.26 | Viral mRNA Translation | REACTOME pathways | R-HSA-192823 | 92 | 15 | 10285 | 41 |
RPL8,RPS20,RPL12,RPS26,RPL13A,RPL18A,RPL14,RPS14,RPL36A,RPL37A,RPL34,RPL35,RPS25,RPL27A,RPS3A |
2.998e-21 | -47.26 | Peptide chain elongation | REACTOME pathways | R-HSA-156902 | 92 | 15 | 10285 | 41 |
RPS26,RPL13A,RPL12,RPL8,RPS20,RPL18A,RPL37A,RPL36A,RPS14,RPL14,RPL27A,RPS3A,RPS25,RPL34,RPL35 |
3.119e-21 | -47.22 | cytoplasmic translation | biological process | GO:0002181 | 126 | 15 | 18204 | 50 |
RPL18A,RPL12,RPL34,RPS20,RPS25,RPS26,RPS14,RPS3A,RPL36A,RPL13A,RPL37A,RPL14,RPL8,RPL27A,RPL35 |
5.014e-21 | -46.74 | Selenocysteine synthesis | REACTOME pathways | R-HSA-2408557 | 95 | 15 | 10285 | 41 |
RPS3A,RPL27A,RPL34,RPL35,RPS25,RPL36A,RPL37A,RPL14,RPS14,RPL18A,RPL13A,RPS26,RPL8,RPS20,RPL12 |
5.929e-21 | -46.57 | Eukaryotic Translation Elongation | REACTOME pathways | R-HSA-156842 | 96 | 15 | 10285 | 41 |
RPL12,RPL8,RPS20,RPL13A,RPS26,RPL18A,RPS14,RPL14,RPL37A,RPL36A,RPS25,RPL34,RPL35,RPL27A,RPS3A |
5.929e-21 | -46.57 | Eukaryotic Translation Termination | REACTOME pathways | R-HSA-72764 | 96 | 15 | 10285 | 41 |
RPL27A,RPS3A,RPL35,RPL34,RPS25,RPL36A,RPL37A,RPL14,RPS14,RPL18A,RPL13A,RPS26,RPL8,RPS20,RPL12 |
9.690e-21 | -46.08 | Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) | REACTOME pathways | R-HSA-975956 | 99 | 15 | 10285 | 41 |
RPL37A,RPL36A,RPS14,RPL14,RPL27A,RPS3A,RPS25,RPL35,RPL34,RPS26,RPL13A,RPL12,RPS20,RPL8,RPL18A |
2.469e-20 | -45.15 | Formation of a pool of free 40S subunits | REACTOME pathways | R-HSA-72689 | 105 | 15 | 10285 | 41 |
RPS25,RPL34,RPL35,RPS3A,RPL27A,RPS14,RPL14,RPL37A,RPL36A,RPL18A,RPL12,RPS20,RPL8,RPS26,RPL13A |
2.555e-20 | -45.11 | Cytoplasmic Ribosomal Proteins | WikiPathways | WP477 | 90 | 15 | 5310 | 28 |
RPS26,RPL12,RPS14,RPL18A,RPL27A,RPL35,RPS20,RPL36A,RPL34,RPL37A,RPS25,RPL14,RPL13A,RPS3A,RPL8 |
1.038e-19 | -43.71 | SRP-dependent cotranslational protein targeting to membrane | REACTOME pathways | R-HSA-1799339 | 115 | 15 | 10285 | 41 |
RPS25,RPL35,RPL34,RPL27A,RPS3A,RPS14,RPL14,RPL37A,RPL36A,RPL18A,RPL12,RPS20,RPL8,RPS26,RPL13A |
1.361e-19 | -43.44 | GTP hydrolysis and joining of the 60S ribosomal subunit | REACTOME pathways | R-HSA-72706 | 117 | 15 | 10285 | 41 |
RPL8,RPS20,RPL12,RPS26,RPL13A,RPL18A,RPL14,RPS14,RPL36A,RPL37A,RPL34,RPL35,RPS25,RPS3A,RPL27A |
1.361e-19 | -43.44 | L13a-mediated translational silencing of Ceruloplasmin expression | REACTOME pathways | R-HSA-156827 | 117 | 15 | 10285 | 41 |
RPL18A,RPL12,RPS20,RPL8,RPS26,RPL13A,RPS25,RPL35,RPL34,RPS3A,RPL27A,RPS14,RPL14,RPL37A,RPL36A |
1.440e-19 | -43.38 | structural constituent of ribosome | molecular function | GO:0003735 | 164 | 15 | 18094 | 49 |
RPL27A,RPL34,RPS14,RPL36A,RPL14,RPS3A,RPS25,RPL35,RPL18A,RPL12,RPL8,RPL13A,RPL37A,RPS20,RPS26 |
2.024e-19 | -43.04 | Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) | REACTOME pathways | R-HSA-975957 | 120 | 15 | 10285 | 41 |
RPL27A,RPS3A,RPL34,RPL35,RPS25,RPL36A,RPL37A,RPL14,RPS14,RPL18A,RPS26,RPL13A,RPL8,RPS20,RPL12 |
2.024e-19 | -43.04 | Nonsense-Mediated Decay (NMD) | REACTOME pathways | R-HSA-927802 | 120 | 15 | 10285 | 41 |
RPL12,RPL8,RPS20,RPL13A,RPS26,RPL18A,RPS14,RPL14,RPL37A,RPL36A,RPS25,RPL35,RPL34,RPL27A,RPS3A |
2.305e-19 | -42.91 | Selenoamino acid metabolism | REACTOME pathways | R-HSA-2408522 | 121 | 15 | 10285 | 41 |
RPL14,RPS14,RPL36A,RPL37A,RPL35,RPL34,RPS25,RPS3A,RPL27A,RPL8,RPS20,RPL12,RPL13A,RPS26,RPL18A |
3.833e-19 | -42.41 | Cap-dependent Translation Initiation | REACTOME pathways | R-HSA-72737 | 125 | 15 | 10285 | 41 |
RPS26,RPL13A,RPL8,RPS20,RPL12,RPL18A,RPL36A,RPL37A,RPL14,RPS14,RPL27A,RPS3A,RPL34,RPL35,RPS25 |
3.833e-19 | -42.41 | Eukaryotic Translation Initiation | REACTOME pathways | R-HSA-72613 | 125 | 15 | 10285 | 41 |
RPL13A,RPS26,RPL12,RPS20,RPL8,RPL18A,RPL37A,RPL36A,RPS14,RPL14,RPL27A,RPS3A,RPS25,RPL34,RPL35 |
5.325e-19 | -42.08 | Ribosome, eukaryotes | KEGG pathways | M00177 | 91 | 15 | 7161 | 41 |
RPL14,RPL13A,RPS25,RPS26,RPL8,RPS20,RPL37A,RPL18A,RPL27A,RPS3A,RPS14,RPL12,RPL34,RPL36A,RPL35 |
5.325e-19 | -42.08 | Ribosome, eukaryotes | KEGG pathways | hsa_M00177 | 91 | 15 | 7161 | 41 |
RPS14,RPL12,RPL36A,RPL34,RPL35,RPL14,RPL13A,RPS25,RPS26,RPL8,RPS20,RPL37A,RPL18A,RPL27A,RPS3A |
5.800e-19 | -41.99 | ribosomal subunit | cellular component | GO:0044391 | 185 | 15 | 19108 | 50 |
RPL37A,RPL12,RPL27A,RPL8,RPL34,RPL13A,RPS25,RPS14,RPL18A,RPS26,RPL36A,RPL35,RPS3A,RPS20,RPL14 |
1.595e-18 | -40.98 | Influenza Viral RNA Transcription and Replication | REACTOME pathways | R-HSA-168273 | 137 | 15 | 10285 | 41 |
RPS20,RPL8,RPL12,RPL13A,RPS26,RPL18A,RPL14,RPS14,RPL36A,RPL37A,RPL34,RPL35,RPS25,RPS3A,RPL27A |
1.698e-18 | -40.92 | PAN2 (poly(A) specific ribonuclease subunit PAN2) | protein interactions | 9924 | 388 | 18 | 19454 | 50 |
SPECC1,RPL37A,RPL12,RPL18A,RPL8,RPL36A,RPL13A,RPS3A,RPL34,RPL14,RPS14,RPL35,RPS25,CSF1R,RPL27A,IVNS1ABP,GNAI2,RPS26 |
3.542e-18 | -40.18 | DNAJC2 (DnaJ heat shock protein family (Hsp40) member C2) | protein interactions | 27000 | 212 | 15 | 19454 | 50 |
RPL14,RPL35,RPS14,RPL34,RPL27A,NTRK1,RPS26,RPL37A,RPS20,RPL8,RPL18A,RPL12,RPS3A,RPL13A,RPL36A |
4.264e-18 | -40.00 | Influenza Life Cycle | REACTOME pathways | R-HSA-168255 | 146 | 15 | 10285 | 41 |
RPL12,RPS20,RPL8,RPS26,RPL13A,RPL18A,RPS14,RPL14,RPL37A,RPL36A,RPS25,RPL35,RPL34,RPL27A,RPS3A |
8.507e-18 | -39.31 | tRNA Charging: Asparagine | SMPDB pathways | SMP0111854 | 79 | 15 | 1369 | 17 |
RPL13A,RPS14,RPL27A,RPS3A,RPL18A,RPL37A,RPL8,RPS26,RPL36A,RPL34,RPL14,RPL35,RPS20,RPS25,RPL12 |
8.507e-18 | -39.31 | tRNA Charging: Proline | SMPDB pathways | SMP0112609 | 79 | 15 | 1369 | 17 |
RPL14,RPL34,RPS20,RPL35,RPS25,RPL12,RPL27A,RPL13A,RPS14,RPL18A,RPL37A,RPS3A,RPL8,RPS26,RPL36A |
8.507e-18 | -39.31 | tRNA Charging: Alanine | SMPDB pathways | SMP0100356 | 79 | 15 | 1369 | 17 |
RPL14,RPL34,RPS20,RPL35,RPL12,RPS25,RPL27A,RPS14,RPL13A,RPL37A,RPL18A,RPS3A,RPL8,RPL36A,RPS26 |
8.507e-18 | -39.31 | tRNA Charging: Arginine | SMPDB pathways | SMP0111853 | 79 | 15 | 1369 | 17 |
RPS3A,RPL37A,RPL18A,RPS14,RPL13A,RPL27A,RPL36A,RPS26,RPL8,RPL35,RPS20,RPL34,RPL14,RPL12,RPS25 |
8.507e-18 | -39.31 | tRNA Charging: Leucine | SMPDB pathways | SMP0111873 | 79 | 15 | 1369 | 17 |
RPL8,RPL36A,RPS26,RPS14,RPL13A,RPL27A,RPS3A,RPL37A,RPL18A,RPL12,RPS25,RPL34,RPL14,RPL35,RPS20 |
8.507e-18 | -39.31 | tRNA Charging: Serine | SMPDB pathways | SMP0119294 | 79 | 15 | 1369 | 17 |
RPL8,RPL36A,RPS26,RPL27A,RPS14,RPL13A,RPL37A,RPL18A,RPS3A,RPL12,RPS25,RPL14,RPL34,RPS20,RPL35 |
8.507e-18 | -39.31 | tRNA Charging: Tyrosine | SMPDB pathways | SMP0119304 | 79 | 15 | 1369 | 17 |
RPS14,RPL13A,RPL27A,RPS3A,RPL37A,RPL18A,RPL8,RPL36A,RPS26,RPL34,RPL14,RPL35,RPS20,RPL12,RPS25 |
8.507e-18 | -39.31 | tRNA Charging: Valine | SMPDB pathways | SMP0119305 | 79 | 15 | 1369 | 17 |
RPL12,RPS25,RPL35,RPS20,RPL34,RPL14,RPL36A,RPS26,RPL8,RPS3A,RPL37A,RPL18A,RPS14,RPL13A,RPL27A |
8.507e-18 | -39.31 | tRNA Charging: Glutamine | SMPDB pathways | SMP0111862 | 79 | 15 | 1369 | 17 |
RPS25,RPL12,RPL34,RPL14,RPL35,RPS20,RPL8,RPS26,RPL36A,RPL13A,RPS14,RPL27A,RPS3A,RPL18A,RPL37A |
8.507e-18 | -39.31 | tRNA Charging: Isoleucine | SMPDB pathways | SMP0111872 | 79 | 15 | 1369 | 17 |
RPL27A,RPL13A,RPS14,RPL18A,RPL37A,RPS3A,RPL8,RPS26,RPL36A,RPL14,RPL34,RPS20,RPL35,RPS25,RPL12 |
8.507e-18 | -39.31 | tRNA Charging: Methionine | SMPDB pathways | SMP0111875 | 79 | 15 | 1369 | 17 |
RPS25,RPL12,RPL34,RPL14,RPL35,RPS20,RPL8,RPS26,RPL36A,RPL13A,RPS14,RPL27A,RPS3A,RPL18A,RPL37A |
8.507e-18 | -39.31 | tRNA Charging: Threonine | SMPDB pathways | SMP0119302 | 79 | 15 | 1369 | 17 |
RPL14,RPL34,RPS20,RPL35,RPL12,RPS25,RPL27A,RPS14,RPL13A,RPL37A,RPL18A,RPS3A,RPL8,RPL36A,RPS26 |
8.507e-18 | -39.31 | tRNA Charging: Aspartic Acid | SMPDB pathways | SMP0111858 | 79 | 15 | 1369 | 17 |
RPL14,RPL34,RPS20,RPL35,RPL12,RPS25,RPL27A,RPS14,RPL13A,RPL37A,RPL18A,RPS3A,RPL8,RPL36A,RPS26 |
8.507e-18 | -39.31 | tRNA Charging: Tryptophan | SMPDB pathways | SMP0119303 | 79 | 15 | 1369 | 17 |
RPL27A,RPL13A,RPS14,RPL18A,RPL37A,RPS3A,RPL8,RPS26,RPL36A,RPL14,RPL34,RPS20,RPL35,RPS25,RPL12 |
8.507e-18 | -39.31 | tRNA Charging: Histidine | SMPDB pathways | SMP0111871 | 79 | 15 | 1369 | 17 |
RPL8,RPS26,RPL36A,RPL13A,RPS14,RPL27A,RPS3A,RPL18A,RPL37A,RPS25,RPL12,RPL34,RPL14,RPL35,RPS20 |
8.507e-18 | -39.31 | tRNA Charging: Cysteine | SMPDB pathways | SMP0111860 | 79 | 15 | 1369 | 17 |
RPL36A,RPS26,RPL8,RPS3A,RPL37A,RPL18A,RPS14,RPL13A,RPL27A,RPL12,RPS25,RPL35,RPS20,RPL34,RPL14 |
8.507e-18 | -39.31 | tRNA Charging: Glycine | SMPDB pathways | SMP0111870 | 79 | 15 | 1369 | 17 |
RPS14,RPL13A,RPL27A,RPS3A,RPL37A,RPL18A,RPL8,RPL36A,RPS26,RPL34,RPL14,RPL35,RPS20,RPL12,RPS25 |
8.507e-18 | -39.31 | tRNA Charging: Lysine | SMPDB pathways | SMP0111874 | 79 | 15 | 1369 | 17 |
RPL27A,RPS14,RPL13A,RPL37A,RPL18A,RPS3A,RPL8,RPL36A,RPS26,RPL14,RPL34,RPS20,RPL35,RPL12,RPS25 |
8.507e-18 | -39.31 | tRNA Charging: Glutamic Acid | SMPDB pathways | SMP0111864 | 79 | 15 | 1369 | 17 |
RPS20,RPL35,RPL14,RPL34,RPL12,RPS25,RPL37A,RPL18A,RPS3A,RPL27A,RPS14,RPL13A,RPL36A,RPS26,RPL8 |
1.281e-17 | -38.90 | tRNA Charging: Phenylalanine | SMPDB pathways | SMP0111876 | 81 | 15 | 1369 | 17 |
RPS3A,RPL37A,RPL18A,RPS14,RPL13A,RPL27A,RPL36A,RPS26,RPL8,RPL35,RPS20,RPL34,RPL14,RPL12,RPS25 |
1.303e-17 | -38.88 | Influenza Infection | REACTOME pathways | R-HSA-168254 | 157 | 15 | 10285 | 41 |
RPS14,RPL14,RPL37A,RPL36A,RPS25,RPL34,RPL35,RPL27A,RPS3A,RPL12,RPL8,RPS20,RPS26,RPL13A,RPL18A |
1.635e-17 | -38.65 | RPL9 (ribosomal protein L9) | protein interactions | 6133 | 364 | 17 | 19454 | 50 |
RPS26,ARAP1,RPL35,RPL14,RPS14,RPL34,RPL27A,NTRK1,RPS25,RPL8,RPL18A,RPL12,PSAP,RPS3A,RPL13A,RPL37A,RPS20 |
1.665e-17 | -38.63 | MICALL2 (MICAL like 2) | protein interactions | 79778 | 137 | 13 | 19454 | 50 |
GNAI2,RPS26,RPL14,RPL35,RPS14,RPL34,RPL27A,RPS25,RPL8,RPL12,RPL18A,RPS3A,RPL13A |
1.701e-17 | -38.61 | NCAPH (non-SMC condensin I complex subunit H) | protein interactions | 23397 | 296 | 16 | 19454 | 50 |
RPS26,CD74,RPL27A,NTRK1,RPS25,RPL35,RPS14,RPL14,RPL34,RPS3A,RPL13A,RPL8,RPL12,RPL18A,RPS20,RPL37A |
2.048e-17 | -38.43 | ribosome | cellular component | GO:0005840 | 234 | 15 | 19108 | 50 |
RPS3A,RPS20,RPL14,RPL18A,RPS26,RPL36A,RPL35,RPS25,RPL13A,RPS14,RPL34,RPL8,RPL12,RPL27A,RPL37A |
2.106e-17 | -38.40 | Translation | REACTOME pathways | R-HSA-72766 | 162 | 15 | 10285 | 41 |
RPL37A,RPL36A,RPS14,RPL14,RPL27A,RPS3A,RPS25,RPL35,RPL34,RPL13A,RPS26,RPL12,RPS20,RPL8,RPL18A |
5.221e-17 | -37.49 | RPL10L (ribosomal protein L10 like) | protein interactions | 140801 | 109 | 12 | 19454 | 50 |
RPS26,PTPN6,RPS14,RPL35,RPL14,RPL27A,RPS25,RPL8,RPL12,RPL18A,RPS3A,RPL37A |
6.079e-17 | -37.34 | REST (RE1 silencing transcription factor) | protein interactions | 5978 | 256 | 15 | 19454 | 50 |
RPL37A,RPS20,RPL8,RPL12,RPL18A,RPS3A,RPL13A,RPL36A,RPL14,RPS14,RPL35,RPL34,RPL27A,RPS25,RPS26 |
9.642e-17 | -36.88 | Major pathway of rRNA processing in the nucleolus and cytosol | REACTOME pathways | R-HSA-6791226 | 179 | 15 | 10285 | 41 |
RPL18A,RPL12,RPS20,RPL8,RPL13A,RPS26,RPS25,RPL34,RPL35,RPS3A,RPL27A,RPS14,RPL14,RPL37A,RPL36A |
1.025e-16 | -36.82 | ATG13 (autophagy related 13) | protein interactions | 9776 | 207 | 14 | 19454 | 50 |
RPL13A,RPS3A,RPL18A,RPL12,RPL8,RPS20,RPL37A,RPS26,RPS25,RPL27A,RPL34,RPL35,RPS14,RPL14 |
1.267e-16 | -36.60 | cytosolic large ribosomal subunit | cellular component | GO:0022625 | 54 | 10 | 19108 | 50 |
RPL14,RPL8,RPL35,RPL36A,RPL18A,RPL13A,RPL27A,RPL12,RPL37A,RPL34 |
1.276e-16 | -36.60 | VRK1 (VRK serine/threonine kinase 1) | protein interactions | 7443 | 269 | 15 | 19454 | 50 |
RPS26,RPS25,RPL27A,RPL34,RPS14,RPL14,RPL35,RPL36A,RPL13A,RPS3A,RPL18A,RPL12,RPL8,RPS20,RPL37A |
1.976e-16 | -36.16 | METAP2 (methionyl aminopeptidase 2) | protein interactions | 10988 | 277 | 15 | 19454 | 50 |
RPL34,RPS14,RPL35,RPL14,RPS25,RPL27A,NTRK1,RPS26,RPL37A,RPS20,RPL12,RPL8,RPL13A,RPL36A,RPS3A |
2.288e-16 | -36.01 | Ribosome | KEGG pathways | ko03010 | 134 | 15 | 7161 | 41 |
RPL35,RPL34,RPL36A,RPS3A,RPL27A,RPL12,RPL18A,RPL37A,RPS14,RPS20,RPL8,RPS26,RPS25,RPL13A,RPL14 |
2.288e-16 | -36.01 | Ribosome | KEGG pathways | hsa03010 | 134 | 15 | 7161 | 41 |
RPL12,RPL35,RPL36A,RPL34,RPS14,RPL27A,RPS3A,RPL18A,RPL37A,RPL13A,RPS25,RPS20,RPL8,RPS26,RPL14 |
2.578e-16 | -35.89 | rRNA processing in the nucleus and cytosol | REACTOME pathways | R-HSA-8868773 | 191 | 15 | 10285 | 41 |
RPS26,RPL13A,RPL12,RPL8,RPS20,RPL18A,RPL37A,RPL36A,RPS14,RPL14,RPS3A,RPL27A,RPS25,RPL34,RPL35 |
2.770e-16 | -35.82 | SRP68 (signal recognition particle 68) | protein interactions | 6730 | 353 | 16 | 19454 | 50 |
RPS3A,RBM47,RPL13A,RPL8,RPL12,RPL18A,RPS20,RPL37A,RPS26,RPL27A,NTRK1,RPS25,RPS14,RPL14,RPL35,RPL34 |
3.183e-16 | -35.68 | RPL38 (ribosomal protein L38) | protein interactions | 6169 | 286 | 15 | 19454 | 50 |
RPS26,RPL34,RPS14,RPL14,RPL35,RPS25,RPL27A,RPL18A,RPL12,RPL8,RPL13A,RPS3A,DCC,RPL37A,RPS20 |
5.227e-16 | -35.19 | RPL10A (ribosomal protein L10a) | protein interactions | 4736 | 448 | 17 | 19454 | 50 |
RPS20,DCC,RPL37A,RPL13A,RPS3A,RPL18A,RPL12,RPL8,RPS25,RPL27A,NTRK1,RPL34,RPS14,RPL35,RPL14,RPS26,PTPN6 |
5.568e-16 | -35.12 | rRNA processing | REACTOME pathways | R-HSA-72312 | 201 | 15 | 10285 | 41 |
RPS25,RPL34,RPL35,RPS3A,RPL27A,RPS14,RPL14,RPL37A,RPL36A,RPL18A,RPL12,RPS20,RPL8,RPS26,RPL13A |
7.476e-16 | -34.83 | RPL22 (ribosomal protein L22) | protein interactions | 6146 | 376 | 16 | 19454 | 50 |
HCK,PTPN6,RPS26,RPL35,RPL14,RPS14,RPL34,RPL27A,RPS25,RPL8,RPL12,RPL18A,RPS3A,RPL13A,RPL37A,RPS20 |
8.666e-16 | -34.68 | SRP19 (signal recognition particle 19) | protein interactions | 6728 | 241 | 14 | 19454 | 50 |
RPS25,RPL27A,RPL34,RPL35,RPS14,RPL14,RPS26,RPS20,RPL37A,RPL13A,RPS3A,RPL12,RPL18A,RPL8 |
1.849e-15 | -33.92 | SRP72 (signal recognition particle 72) | protein interactions | 6731 | 322 | 15 | 19454 | 50 |
RPS20,RPL37A,RPS3A,RPL13A,RPL8,RPL18A,RPL12,RPL27A,NTRK1,RPS25,RPL14,RPS14,RPL35,RPL34,RPS26 |
2.120e-15 | -33.79 | RPL21 (ribosomal protein L21) | protein interactions | 6144 | 325 | 15 | 19454 | 50 |
RPL13A,RPS3A,RPL12,RPL18A,RPL8,RPS20,RPL37A,PTPN6,RPS26,RPS25,RPL27A,RPL34,RPL35,RPL14,RPS14 |
2.322e-15 | -33.70 | RBM42 (RNA binding motif protein 42) | protein interactions | 79171 | 327 | 15 | 19454 | 50 |
RPS26,RPS25,RPL27A,NTRK1,RPL34,RPS14,RPL14,RPL35,RPL13A,RPS3A,RPL12,RPL18A,RPL8,RPS20,RPL37A |
4.382e-15 | -33.06 | CTCF (CCCTC-binding factor) | protein interactions | 10664 | 421 | 16 | 19454 | 50 |
RPS25,RPL27A,RPL34,RPS14,RPL14,RPL35,RPS26,SYK,RPS20,RPL37A,RPL13A,RXRA,RPS3A,RPL12,RPL18A,RPL8 |
7.036e-15 | -32.59 | RPS13 (ribosomal protein S13) | protein interactions | 6207 | 434 | 16 | 19454 | 50 |
RPL34,RPL35,RPS14,RPL14,RPS25,RPL27A,NTRK1,RPS26,DCC,RPL37A,RPS20,RPL18A,RPL12,RPL8,RPL13A,RPS3A |
9.023e-15 | -32.34 | RPL7 (ribosomal protein L7) | protein interactions | 6129 | 441 | 16 | 19454 | 50 |
RPL37A,RPS20,RPL8,RPL12,RPL18A,RPS3A,RPL13A,RPS14,RPL35,RPL14,RPL34,RPL27A,NTRK1,RPS25,RPS26,PTPN6 |
9.445e-15 | -32.29 | RPL6 (ribosomal protein L6) | protein interactions | 6128 | 534 | 17 | 19454 | 50 |
RPS3A,RPL13A,RPL8,RPL12,RPL18A,RPS20,RPL37A,PTPN6,RPS26,IVNS1ABP,NTRK1,RPL27A,RPS25,RPS14,RPL35,RPL14,RPL34 |
1.003e-14 | -32.23 | TRIM31 (tripartite motif containing 31) | protein interactions | 11074 | 444 | 16 | 19454 | 50 |
RPL36A,RPL13A,RPS3A,RPL18A,RPL12,RPL8,RPS20,RPL37A,RPS26,SYK,RPS25,RPL27A,RPL34,RPL14,RPS14,RPL35 |
1.031e-14 | -32.21 | EIF2S3 (eukaryotic translation initiation factor 2 subunit gamma) | protein interactions | 1968 | 288 | 14 | 19454 | 50 |
NTRK1,RPL27A,RPS25,RPL35,RPL14,RPS14,RPL34,CD74,RPS26,RPS20,DCC,RPS3A,RPL13A,RPL8 |
1.956e-14 | -31.57 | RPL27 (ribosomal protein L27) | protein interactions | 6155 | 378 | 15 | 19454 | 50 |
RPL37A,RPS20,RPL12,RPL18A,RPL8,RPL13A,RPS3A,RPL34,RPL14,RPS14,RPL35,RPS25,RPL27A,RPS26,PTPN6 |
2.602e-14 | -31.28 | RPL32 (ribosomal protein L32) | protein interactions | 6161 | 308 | 14 | 19454 | 50 |
RPL12,RPL18A,RPL8,RPL13A,RPS3A,RPL37A,RPS20,RPS26,PTPN6,RPL34,RPS14,RPL14,RPL35,RPL27A |
2.971e-14 | -31.15 | Infectious disease | REACTOME pathways | R-HSA-5663205 | 388 | 17 | 10285 | 41 |
RPL12,RPL8,RPS20,RPS26,RPL13A,ELMO1,RPL18A,RPS14,HCK,RPL14,RPL37A,RPL36A,RPS25,RPL34,RPL35,RPS3A,RPL27A |
3.075e-14 | -31.11 | RPL5 (ribosomal protein L5) | protein interactions | 6125 | 574 | 17 | 19454 | 50 |
RPS26,PTPN6,RPL35,RPS14,RPL14,RPL34,RPL27A,NTRK1,RPS25,RPL8,RPL18A,RPL12,RPS3A,RPL13A,RPL37A,DCC,RPS20 |
3.354e-14 | -31.03 | RPL18 (ribosomal protein L18) | protein interactions | 6141 | 480 | 16 | 19454 | 50 |
PTPN6,RPS26,RPL14,RPL35,RPS14,RPL34,NTRK1,RPL27A,RPS25,RPL8,RPL18A,RPL12,RPS3A,RPL13A,RPL37A,RPS20 |
4.194e-14 | -30.80 | RPL15 (ribosomal protein L15) | protein interactions | 6138 | 487 | 16 | 19454 | 50 |
RPS3A,RPL13A,RPL8,RPL18A,RPL12,RPS20,RPL37A,PTPN6,RPS26,NTRK1,RPL27A,RPS25,RPS14,RPL14,RPL35,RPL34 |
5.067e-14 | -30.61 | G3BP2 (G3BP stress granule assembly factor 2) | protein interactions | 9908 | 493 | 16 | 19454 | 50 |
RPS25,RPL27A,NTRK1,RPL34,RPL14,RPL35,RPS14,RPS26,IVNS1ABP,RPS20,RBM47,RPL13A,RPS3A,RPL18A,RPL12,RPL8 |
6.149e-14 | -30.42 | translation | biological process | GO:0006412 | 383 | 15 | 18204 | 50 |
RPL27A,RPL14,RPL8,RPL35,RPL13A,RPL37A,RPS20,RPS25,RPL34,RPS14,RPS3A,RPL36A,RPS26,RPL18A,RPL12 |
6.994e-14 | -30.29 | RPL34 (ribosomal protein L34) | protein interactions | 6164 | 259 | 13 | 19454 | 50 |
RPS20,RPL37A,RPS3A,RPL13A,RPL8,RPL12,RPL27A,RPS25,RPL35,RPL14,RPS14,RPS26,PTPN6 |
7.292e-14 | -30.25 | RRS1 (ribosome biogenesis regulator 1 homolog) | protein interactions | 23212 | 332 | 14 | 19454 | 50 |
RPL13A,RPS3A,RPL18A,RPL8,RPS20,RPL37A,RPS26,PTPN6,SYK,RPS25,RPL34,RPL35,RPS14,RPL14 |
8.540e-14 | -30.09 | POLY (polyprotein;protein F) | protein interactions | 951475 | 510 | 16 | 19454 | 50 |
RPL37A,RPS20,RPL12,RPL18A,RPS3A,RBM47,RPL13A,RPL36A,RPL35,RPL14,RPS14,RPL34,RPL27A,RPS25,HCK,RPS26 |
1.095e-13 | -29.84 | RPS23 (ribosomal protein S23) | protein interactions | 6228 | 342 | 14 | 19454 | 50 |
RPS14,RPL14,RPL35,RPL34,RPL27A,RPS25,RPS26,RPL37A,RPS20,RPL8,RPL12,RPL18A,RPS3A,RPL13A |
1.139e-13 | -29.80 | FBP1 (fructose-bisphosphatase 1) | protein interactions | 2203 | 343 | 14 | 19454 | 50 |
RPL37A,DCC,RPS20,RPL8,RPL18A,RPL12,RPS3A,RPL36A,RPS14,RPL35,RPL14,RPL34,RPL27A,RPS26 |
1.185e-13 | -29.76 | RPS25 (ribosomal protein S25) | protein interactions | 6230 | 344 | 14 | 19454 | 50 |
RPL34,RPL14,RPL35,RPS14,RPL27A,NTRK1,RPS26,RPL37A,RPS20,RPL18A,RPL12,RPL8,RPL13A,RPS3A |
1.444e-13 | -29.57 | RPL24 (ribosomal protein L24) | protein interactions | 6152 | 349 | 14 | 19454 | 50 |
RPS25,RPL27A,RPL34,RPL35,RPL14,RPS14,RPS26,RPS20,RPL37A,RPL13A,RPS3A,RPL18A,RPL12,RPL8 |
1.618e-13 | -29.45 | RPL30 (ribosomal protein L30) | protein interactions | 6156 | 437 | 15 | 19454 | 50 |
RPL14,RPL35,RPS14,RPL34,RPL27A,RPS25,RPS26,PTPN6,RPL37A,RPS20,RPL8,RPL12,RPL18A,RPS3A,RPL13A |
1.687e-13 | -29.41 | DRG1 (developmentally regulated GTP binding protein 1) | protein interactions | 4733 | 353 | 14 | 19454 | 50 |
RPS26,NTRK1,RPL27A,RPS25,RPL14,RPL35,RPS14,RPL34,RPS3A,RPL13A,RPL8,RPL12,RPS20,RPL37A |
1.996e-13 | -29.24 | RPL17 (ribosomal protein L17) | protein interactions | 6139 | 539 | 16 | 19454 | 50 |
RPL27A,NTRK1,RPS25,RPL14,RPS14,RPL35,RPS26,PTPN6,RPS20,RPL37A,RPS3A,RBM47,RPL13A,RPL8,RPL18A,RPL12 |
2.029e-13 | -29.23 | ENY2 (ENY2 transcription and export complex 2 subunit) | protein interactions | 56943 | 158 | 11 | 19454 | 50 |
RPL18A,RPL8,RPL13A,RPS3A,RPL34,RPL35,RPL37A,RPL14,RPS20,RPS25,RPL27A |
2.104e-13 | -29.19 | RPS4X (ribosomal protein S4 X-linked) | protein interactions | 6191 | 445 | 15 | 19454 | 50 |
RPL12,RPL18A,RPL8,RPL13A,RPS3A,DCC,RPL37A,RPS20,RPS26,RPL35,RPL14,RPS14,RPS25,NTRK1,RPL27A |
2.123e-13 | -29.18 | RPS15 (ribosomal protein S15) | protein interactions | 6209 | 359 | 14 | 19454 | 50 |
RPL34,RPS14,RPL14,RPL35,RPS25,RPL27A,SYK,RPS26,RPL37A,RPS20,RPL18A,RPL8,RPL13A,RPS3A |
2.144e-13 | -29.17 | RPL13 (ribosomal protein L13) | protein interactions | 6137 | 647 | 17 | 19454 | 50 |
DCC,RPL37A,RPS20,RPL12,RPL18A,RPL8,RPL13A,RPS3A,RPL34,RPS14,RPL35,RPL14,RPS25,RPL27A,NTRK1,RPS26,PTPN6 |
2.447e-13 | -29.04 | large ribosomal subunit | cellular component | GO:0015934 | 111 | 10 | 19108 | 50 |
RPL37A,RPL34,RPL13A,RPL27A,RPL12,RPL36A,RPL8,RPL35,RPL18A,RPL14 |
2.660e-13 | -28.96 | RPL12 (ribosomal protein L12) | protein interactions | 6136 | 365 | 14 | 19454 | 50 |
RPL18A,RPL8,RPL13A,RPS3A,RPL37A,RPS20,PTPN6,RPS26,RPL34,RPS14,RPL35,RPL14,RPS25,RPL27A |
2.675e-13 | -28.95 | EMC9 (ER membrane protein complex subunit 9) | protein interactions | 51016 | 162 | 11 | 19454 | 50 |
RPL27A,RPS20,RPS25,RPL14,RPL37A,RPL34,RPS3A,RPL13A,RPL8,RPL12,RPL18A |
2.866e-13 | -28.88 | RPL37A (ribosomal protein L37a) | protein interactions | 6168 | 367 | 14 | 19454 | 50 |
PTPN6,RPS26,RPL14,RPS14,RPL35,RPL34,RPL27A,RPS25,RPL8,RPL18A,RPL12,RPS3A,RPL13A,RPS20 |
2.991e-13 | -28.84 | BTF3 (basic transcription factor 3) | protein interactions | 689 | 777 | 18 | 19454 | 50 |
RPS20,RPL37A,SPECC1,RPS3A,RPL36A,RPL13A,RPL8,RPL18A,RPL12,RPL27A,RPS25,RPL35,RPS14,RPL14,RPL34,RPS26,GNAI2,SYK |
3.124e-13 | -28.79 | RPS6 (ribosomal protein S6) | protein interactions | 6194 | 779 | 18 | 19454 | 50 |
RPS3A,RBM47,RPL13A,RPL36A,RPL8,RPL12,RPL18A,RPS20,RPL37A,DCC,RPS26,RPL27A,NTRK1,RPS25,RPL14,RPS14,RPL35,RPL34 |
3.190e-13 | -28.77 | RPS11 (ribosomal protein S11) | protein interactions | 6205 | 458 | 15 | 19454 | 50 |
RPL37A,RPS20,RPL18A,RPL12,RPL8,RPL36A,RPL13A,RPS3A,RPL34,RPL35,RPL14,RPS14,RPS25,RPL27A,RPS26 |
3.445e-13 | -28.70 | RPS18 (ribosomal protein S18) | protein interactions | 6222 | 372 | 14 | 19454 | 50 |
RPS26,RPL34,RPL14,RPL35,RPS14,RPS25,RPL27A,RPL18A,RPL12,RPL8,RPL13A,RPS3A,RPL37A,RPS20 |
3.485e-13 | -28.69 | RPL19 (ribosomal protein L19) | protein interactions | 6143 | 559 | 16 | 19454 | 50 |
RPL37A,RPS20,RPL18A,RPL12,RPL8,RPL13A,RPS3A,RPL34,RPL35,RPS14,RPL14,RPS25,RPL27A,NTRK1,RPS26,PTPN6 |
3.984e-13 | -28.55 | RPS5 (ribosomal protein S5) | protein interactions | 6193 | 376 | 14 | 19454 | 50 |
RPL18A,RPL12,RPL8,RPL13A,RPS3A,RPL37A,RPS20,RPS26,RPS14,RPL14,RPL35,RPS25,NTRK1,RPL27A |
4.391e-13 | -28.45 | RPS26 (ribosomal protein S26) | protein interactions | 6231 | 299 | 13 | 19454 | 50 |
RPS25,RPL27A,RPL34,RPS14,RPL14,RPL35,RPL13A,RPS3A,RPL18A,RPL12,RPL8,RPS20,RPL37A |
4.778e-13 | -28.37 | RPL36 (ribosomal protein L36) | protein interactions | 25873 | 471 | 15 | 19454 | 50 |
RPS25,RPL27A,RPL34,RPL35,RPL14,RPS14,RPS26,PTPN6,RPS20,RPL37A,RPL13A,RPS3A,RPL12,RPL18A,RPL8 |
4.940e-13 | -28.34 | RPS15A (ribosomal protein S15a) | protein interactions | 6210 | 382 | 14 | 19454 | 50 |
RPL13A,RPS3A,RPL12,RPL18A,RPL8,RPS20,RPL37A,RPS26,RPS25,RPL27A,RPL34,RPL14,RPL35,RPS14 |
6.144e-13 | -28.12 | RPS27 (ribosomal protein S27) | protein interactions | 6232 | 307 | 13 | 19454 | 50 |
RPL27A,RPS25,RPS14,RPL35,RPL14,RPL34,RPS26,RPS20,RPS3A,RPL13A,RPL8,RPL12,RPL18A |
6.663e-13 | -28.04 | RPS9 (ribosomal protein S9) | protein interactions | 6203 | 482 | 15 | 19454 | 50 |
RPL37A,RPS20,RPL18A,RPL12,RPL8,RPL13A,RPS3A,RPL34,RPL14,RPS14,RPL35,RPS25,NTRK1,RPL27A,RPS26 |
6.880e-13 | -28.01 | RPLP0P6 (ribosomal protein lateral stalk subunit P0 pseudogene 6) | protein interactions | 220717 | 125 | 10 | 19454 | 50 |
RPS3A,RPS26,RPL8,RPL18A,RPL12,RPS25,RPS20,RPS14,RPL14,RPL37A |
7.286e-13 | -27.95 | RPL8 (ribosomal protein L8) | protein interactions | 6132 | 485 | 15 | 19454 | 50 |
RPS26,PTPN6,RPS25,RPL27A,NTRK1,RPL34,RPS14,RPL35,RPL14,RPL13A,RPS3A,RPL18A,RPL12,RPS20,RPL37A |
7.535e-13 | -27.91 | RPS2 (ribosomal protein S2) | protein interactions | 6187 | 588 | 16 | 19454 | 50 |
RPL8,RPL12,RPL18A,RPS3A,RBM47,RPL13A,RPL37A,RPS20,RPS26,RPL14,RPL35,RPS14,RPL34,NTRK1,RPL27A,RPS25 |
7.730e-13 | -27.89 | RPSA (ribosomal protein SA) | protein interactions | 3921 | 487 | 15 | 19454 | 50 |
RPS20,RPL37A,RPL13A,RPS3A,RPL12,RPL18A,RPL8,RPS25,RPL27A,NTRK1,RPL34,RPL35,RPS14,RPL14,RPS26 |
8.199e-13 | -27.83 | RPL14 (ribosomal protein L14) | protein interactions | 9045 | 489 | 15 | 19454 | 50 |
RPL13A,RPS3A,RPL12,RPL18A,RPL8,RPS20,RPL37A,PTPN6,RPS26,RPS25,NTRK1,RPL27A,RPL34,RPL35,RPS14 |
8.571e-13 | -27.79 | RPL7A (ribosomal protein L7a) | protein interactions | 6130 | 593 | 16 | 19454 | 50 |
RPS26,PTPN6,RPL27A,NTRK1,RPS25,RPS14,RPL35,RPL14,RPL34,RPS3A,RPL13A,RPL8,RPL12,RPL18A,RPS20,RPL37A |
1.006e-12 | -27.63 | RPL23 (ribosomal protein L23) | protein interactions | 9349 | 496 | 15 | 19454 | 50 |
RPS3A,RPL13A,RPL8,RPL18A,RPL12,RPS20,RPL37A,DCC,RPS26,RPL27A,RPS25,RPL35,RPS14,RPL14,RPL34 |
1.287e-12 | -27.38 | PAGE4 (PAGE family member 4) | protein interactions | 9506 | 251 | 12 | 19454 | 50 |
RPL34,RPL14,RPS20,RPS25,RPL27A,RPL12,RPL18A,IVNS1ABP,RPL8,RPL36A,RPL13A,RPS3A |
1.458e-12 | -27.25 | RPL13A (ribosomal protein L13a) | protein interactions | 23521 | 509 | 15 | 19454 | 50 |
RPS3A,RPL12,RPL18A,RPL8,RPS20,RPL37A,PTPN6,RPS26,RPS25,NTRK1,RPL27A,RPL34,RPS14,RPL35,RPL14 |
1.677e-12 | -27.11 | RPL35 (ribosomal protein L35) | protein interactions | 11224 | 514 | 15 | 19454 | 50 |
RPS25,RPL27A,RPL34,RPS14,RPL14,RPL35,PTPN6,RPS26,RPS20,RPL37A,RPL13A,RPS3A,RPL12,RPL18A,RPL8 |
2.412e-12 | -26.75 | UBL4A (ubiquitin like 4A) | protein interactions | 8266 | 342 | 13 | 19454 | 50 |
RPS26,RPL27A,RPS25,RPS14,RPL14,RPL34,RPS3A,RPL13A,RPL8,RPL12,RPL18A,RPS20,RPL37A |
2.793e-12 | -26.60 | MAGEB2 (MAGE family member B2) | protein interactions | 4113 | 346 | 13 | 19454 | 50 |
RPL8,RPL18A,RPL12,RPS3A,RPL36A,RPL37A,HCK,RPS26,RPL35,RPL14,RPS14,RPL34,RPL27A |
3.053e-12 | -26.51 | RPS10 (ribosomal protein S10) | protein interactions | 6204 | 536 | 15 | 19454 | 50 |
RPL13A,RPS3A,RPL18A,RPL12,RPL8,RPS20,DCC,RPL37A,RPS26,SYK,RPS25,RPL27A,RPL35,RPS14,RPL14 |
3.134e-12 | -26.49 | Metabolism of amino acids and derivatives | REACTOME pathways | R-HSA-71291 | 361 | 15 | 10285 | 41 |
RPL8,RPS20,RPL12,RPS26,RPL13A,RPL18A,RPL14,RPS14,RPL36A,RPL37A,RPL35,RPL34,RPS25,RPS3A,RPL27A |
3.220e-12 | -26.46 | ITFG1 (integrin alpha FG-GAP repeat containing 1) | protein interactions | 81533 | 538 | 15 | 19454 | 50 |
RPL37A,RPS20,RPL8,RPL12,RPL18A,RPS3A,RPL36A,RPL13A,RPS14,RPL35,RPL14,RPL34,RPL27A,RPS25,RPS26 |
3.220e-12 | -26.46 | RPL3L (ribosomal protein L3 like) | protein interactions | 6123 | 62 | 8 | 19454 | 50 |
RPS26,RPL8,RPL18A,RPL27A,RPS25,RPS20,RPL37A,RPL14 |
3.542e-12 | -26.37 | RBM8A (RNA binding motif protein 8A) | protein interactions | 9939 | 442 | 14 | 19454 | 50 |
RPL8,RPL12,RPL18A,RPS3A,RPL13A,RPL37A,RPS20,RPS26,RPS14,RPL35,RPL14,RPL34,RPL27A,RPS25 |
4.245e-12 | -26.19 | NFX1 (nuclear transcription factor, X-box binding 1) | protein interactions | 4799 | 448 | 14 | 19454 | 50 |
IVNS1ABP,RPS14,RPL35,RPL34,RPL27A,RPS25,RPL8,RPL12,RPL18A,RPS3A,RPL36A,RPL13A,RPL37A,RPS20 |
4.644e-12 | -26.10 | RPL23A (ribosomal protein L23a) | protein interactions | 6147 | 552 | 15 | 19454 | 50 |
RPL37A,RPS20,RPL12,RPL18A,RPL8,RPL13A,RPS3A,RPL34,RPL14,RPS14,RPL35,RPS25,RPL27A,PTPN6,RPS26 |
4.854e-12 | -26.05 | RPL10 (ribosomal protein L10) | protein interactions | 6134 | 665 | 16 | 19454 | 50 |
RPS25,RPL27A,NTRK1,RPL35,RPS14,RPL14,RPS26,PTPN6,HCK,RPS20,RPL37A,RPL13A,RPS3A,RPL18A,RPL12,RPL8 |
5.109e-12 | -26.00 | RPL35A (ribosomal protein L35a) | protein interactions | 6165 | 363 | 13 | 19454 | 50 |
RPL14,RPS14,RPL35,RPL34,RPL27A,RPS25,PTPN6,RPS20,RPL8,RPL12,RPL18A,RPS3A,RPL13A |
6.718e-12 | -25.73 | RPLP2 (ribosomal protein lateral stalk subunit P2) | protein interactions | 6181 | 371 | 13 | 19454 | 50 |
RPS26,RPS14,RPL14,RPL35,RPL27A,RPS25,RPL8,RPL12,RPL18A,RPS3A,RPL13A,RPL37A,RPS20 |
7.095e-12 | -25.67 | RPL4 (ribosomal protein L4) | protein interactions | 6124 | 682 | 16 | 19454 | 50 |
RPL37A,RPS20,RPL8,RPL18A,RPL12,RPS3A,RPL13A,RPL14,RPS14,RPL35,RPL34,RPL27A,NTRK1,RPS25,RPS26,PTPN6 |
7.347e-12 | -25.64 | Apc2 (Adenomatous polyposis coli 2) | protein interactions | 42871 | 807 | 17 | 19454 | 50 |
RPS26,RPL34,RPL14,RPS14,RPL35,RPS25,RPL27A,RPL18A,RPL12,RPL8,RPL36A,RPL13A,RPS3A,PSAP,SPECC1,RPL37A,RPS20 |
7.641e-12 | -25.60 | Rrbp1 (ribosome binding protein 1) | protein interactions | 81910 | 220 | 11 | 19454 | 50 |
RPS25,RPS20,RPL35,RPL14,RPS14,RPS3A,RPL13A,RPL36A,RPL8,RPL18A,RPL12 |
8.254e-12 | -25.52 | GSPT1 (G1 to S phase transition 1) | protein interactions | 2935 | 294 | 12 | 19454 | 50 |
NTRK1,RPL27A,RPS20,RPS25,RPL35,RPS14,RPL14,RPL34,RPS3A,RPS26,RPL13A,RPL8 |
8.745e-12 | -25.46 | Eif3e (eukaryotic translation initiation factor 3, subunit E) | protein interactions | 16341 | 110 | 9 | 19454 | 50 |
RPS20,RPL27A,RPS14,RPL37A,RPL13A,RPS3A,RPL18A,RPL12,RPL8 |
9.294e-12 | -25.40 | RPLP1 (ribosomal protein lateral stalk subunit P1) | protein interactions | 6176 | 297 | 12 | 19454 | 50 |
RPS20,RPS25,RPL27A,RPL34,RPL14,RPL37A,RPS14,RPL13A,RPS26,RPS3A,RPL12,RPL18A |
9.294e-12 | -25.40 | RPS12 (ribosomal protein S12) | protein interactions | 6206 | 297 | 12 | 19454 | 50 |
RPL27A,RPS20,RPS25,RPL35,RPS14,RPL37A,RPL14,RPS3A,RPS26,RPL13A,RPL18A,RPL12 |
1.023e-11 | -25.31 | FOLR1 (folate receptor alpha) | protein interactions | 2348 | 226 | 11 | 19454 | 50 |
RPS3A,RPL18A,RPL12,RPL8,RPS20,RPS25,RPL27A,RPL34,RPS14,RPL35,RPL14 |
1.178e-11 | -25.16 | PRKRA (protein activator of interferon induced protein kinase EIF2AK2) | protein interactions | 8575 | 388 | 13 | 19454 | 50 |
RPS26,SYK,RPL27A,RPL14,RPL35,RPS14,RPL34,RPS3A,RPL13A,RPL8,RPL18A,RPL12,RPL37A |
1.243e-11 | -25.11 | PPP1CC (protein phosphatase 1 catalytic subunit gamma) | protein interactions | 5501 | 708 | 16 | 19454 | 50 |
RPS26,RPL27A,RPS25,RPL35,BMP2K,RPL14,RPS14,RPL34,RPS3A,RPL13A,RPL8,RPL12,RPL18A,RPS20,RPL37A,SPECC1 |
1.333e-11 | -25.04 | CUL1 (cullin 1) | protein interactions | 8454 | 838 | 17 | 19454 | 50 |
RPS25,RPL27A,NTRK1,CSF1R,RPL34,RPS14,RPL35,RPL14,RPL13A,RPS3A,HIPK2,RPL12,RPL18A,RPL8,RPS20,PDE6D,RPL37A |
1.427e-11 | -24.97 | RPS7 (ribosomal protein S7) | protein interactions | 6201 | 394 | 13 | 19454 | 50 |
RPL27A,RPS25,RPL14,RPL35,RPS14,RPS26,RPS20,RPL37A,RPS3A,RPL13A,RPL8,RPL18A,RPL12 |
1.552e-11 | -24.89 | RPS8 (ribosomal protein S8) | protein interactions | 6202 | 601 | 15 | 19454 | 50 |
RPL13A,RPS3A,RPL18A,RPL12,RPL8,RPS20,RPL37A,RPS26,RPS25,RPL27A,NTRK1,RPL34,RPL35,RPS14,RPL14 |
1.779e-11 | -24.75 | ARIH2 (ariadne RBR E3 ubiquitin protein ligase 2) | protein interactions | 10425 | 314 | 12 | 19454 | 50 |
RPL14,RPS14,NTRK1,RPL27A,RPS20,RPS25,RPL8,RPL12,RPS3A,ARAP1,RPL13A,RPS26 |
2.084e-11 | -24.59 | Eif3a (eukaryotic translation initiation factor 3, subunit A) | protein interactions | 13669 | 121 | 9 | 19454 | 50 |
RPL14,RPS14,RPL27A,RPS25,RPS20,RPL8,RPL18A,RPS3A,RPL13A |
2.100e-11 | -24.59 | RPL11 (ribosomal protein L11) | protein interactions | 6135 | 614 | 15 | 19454 | 50 |
RPL37A,RPS20,RPL18A,RPL12,RPL8,RPL13A,RPS3A,RPL34,RPS14,RPL14,RPL35,RPS25,RPL27A,RPS26,PTPN6 |
2.100e-11 | -24.59 | RPLP0 (ribosomal protein lateral stalk subunit P0) | protein interactions | 6175 | 614 | 15 | 19454 | 50 |
RPS26,RPL27A,NTRK1,RPS25,RPL35,RPS14,RPL14,RPL34,RPS3A,RPL13A,RPL8,RPL12,RPL18A,RPS20,RPL37A |
2.249e-11 | -24.52 | MIDN (midnolin) | protein interactions | 90007 | 617 | 15 | 19454 | 50 |
GNAI2,RPL27A,RPS25,RPL14,RPS14,RPL35,RPL34,RPS3A,RPL36A,RPL13A,RPL8,RPL18A,RPL12,RPS20,RPL37A |
2.345e-11 | -24.48 | RPL18A (ribosomal protein L18a) | protein interactions | 6142 | 410 | 13 | 19454 | 50 |
PTPN6,RPS26,RPL27A,RPS25,RPS14,RPL35,RPL14,RPS3A,RPL13A,RPL8,RPL12,RPS20,RPL37A |
2.471e-11 | -24.42 | RCHY1 (ring finger and CHY zinc finger domain containing 1) | protein interactions | 25898 | 323 | 12 | 19454 | 50 |
RPL34,RPL35,RPS14,RPL14,RPS25,RPL27A,RPL37A,RPL18A,RPL12,RPL8,RPL13A,RPS3A |
2.557e-11 | -24.39 | PUM3 (pumilio RNA binding family member 3) | protein interactions | 9933 | 246 | 11 | 19454 | 50 |
RPL37A,RPS3A,RPL13A,RPL8,RPL12,RPL18A,NTRK1,RPL14,RPL35,RPS14,RPL34 |
2.788e-11 | -24.30 | CAPZB (capping actin protein of muscle Z-line subunit beta) | protein interactions | 832 | 1019 | 18 | 19454 | 50 |
RPL36A,RPL13A,RPS3A,RPL12,RPL18A,RPL8,RPS20,SPECC1,RPL37A,ARAP1,RPS26,RPS25,NTRK1,RPL27A,RPL34,RPS14,RPL14,RPL35 |
2.982e-11 | -24.24 | RPL27A (ribosomal protein L27a) | protein interactions | 6157 | 418 | 13 | 19454 | 50 |
RPS20,RPL37A,RPL13A,RPS3A,RPL18A,RPL12,RPL8,RPS25,RPL34,RPL35,RPS14,RPL14,RPS26 |
4.001e-11 | -23.94 | CAPRIN1 (cell cycle associated protein 1) | protein interactions | 4076 | 428 | 13 | 19454 | 50 |
RPS20,RPL37A,RPL13A,RPS3A,RPL8,RPS25,RPL27A,NTRK1,RPL34,RPS14,RPL35,RPL14,RPS26 |
4.636e-11 | -23.79 | PTPN6 (protein tyrosine phosphatase non-receptor type 6) | protein interactions | 5777 | 260 | 11 | 19454 | 50 |
NTRK1,RPL34,RPL37A,RPL35,RPL14,PTPN6,RPL13A,RPL18A,RPL12,SYK,RPL8 |
5.236e-11 | -23.67 | B3GNT2 (UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2) | protein interactions | 10678 | 541 | 14 | 19454 | 50 |
RPS26,RPL34,RPL14,RPS14,RPL35,RPL27A,RPL12,RPL18A,RPL8,RPL36A,RPL13A,RPS3A,RPL37A,RPS20 |
5.297e-11 | -23.66 | HDAC6 (histone deacetylase 6) | protein interactions | 10013 | 915 | 17 | 19454 | 50 |
RPS3A,RPL36A,RPL13A,RPL8,RPL12,RPL18A,RPS20,RPS26,GNAI2,SYK,NTRK1,RPL27A,RPS25,RPL35,RPL14,RPS14,RPL34 |
5.559e-11 | -23.61 | RACK1 (receptor for activated C kinase 1) | protein interactions | 10399 | 658 | 15 | 19454 | 50 |
SYK,RPS26,RPL14,RPS14,RPL35,RPL34,NTRK1,RPL27A,RPS25,RPL8,RPL12,RPS3A,RPL13A,RPL37A,RPS20 |
5.800e-11 | -23.57 | RPS3 (ribosomal protein S3) | protein interactions | 6188 | 660 | 15 | 19454 | 50 |
RPS20,RPL37A,RPS3A,RPL13A,RPL8,RPL12,RPL18A,NTRK1,RPL27A,RPS25,RPL14,RPS14,RPL35,RPL34,RPS26 |
6.447e-11 | -23.46 | RC3H2 (ring finger and CCCH-type domains 2) | protein interactions | 54542 | 665 | 15 | 19454 | 50 |
IVNS1ABP,RPS14,RPL14,RPL35,RPS25,RPL27A,RPL12,RPL18A,RPL8,RPL36A,RBM47,RPL13A,RPS3A,RPL37A,RPS20 |
6.724e-11 | -23.42 | RPL3 (ribosomal protein L3) | protein interactions | 6122 | 667 | 15 | 19454 | 50 |
RPL37A,RPS20,RPL12,RPL18A,RPL8,RPL13A,RPS3A,RPL34,RPL35,RPL14,RPS14,RPS25,NTRK1,RPL27A,RPS26 |
7.865e-11 | -23.27 | RPA4 (replication protein A4) | protein interactions | 29935 | 452 | 13 | 19454 | 50 |
RPL14,RPL35,RPL34,RPL27A,RPS25,RPL37A,RAPGEF6,RPS20,RPL8,RPL12,RPL18A,RPS3A,RPL13A |
8.368e-11 | -23.20 | ZNF770 (zinc finger protein 770) | protein interactions | 54989 | 92 | 8 | 19454 | 50 |
RPL27A,RPL14,RPL35,RPL37A,RPL13A,RPS3A,RPL18A,RPL8 |
9.137e-11 | -23.12 | RPS17 (ribosomal protein S17) | protein interactions | 6218 | 277 | 11 | 19454 | 50 |
RPS3A,RPS26,PTPN6,RPL8,RPL12,RPS25,RPS20,RPL14,RPS14,RPL37A,RPL35 |
1.274e-10 | -22.78 | RPS20 (ribosomal protein S20) | protein interactions | 6224 | 470 | 13 | 19454 | 50 |
RPS14,RPL35,RPL14,RPL34,RPL27A,RPS25,RPS26,RPL37A,RPL8,RPL12,RPL18A,RPS3A,RPL13A |
1.385e-10 | -22.70 | DDX27 (DEAD-box helicase 27) | protein interactions | 55661 | 288 | 11 | 19454 | 50 |
RPL37A,RPL18A,RPL8,RPL13A,RPS3A,RPL35,RPL14,RPS14,NTRK1,SYK,PTPN6 |
1.451e-10 | -22.65 | RPS14 (ribosomal protein S14) | protein interactions | 6208 | 475 | 13 | 19454 | 50 |
RPL12,RPL18A,RPL8,RPL13A,RPS3A,RPL37A,RPS20,RPS26,RPL34,RPL35,RPL14,RPS25,RPL27A |
1.471e-10 | -22.64 | DUX4 (double homeobox 4) | protein interactions | 100288687 | 214 | 10 | 19454 | 50 |
RPL12,RPL8,RPS3A,RPL34,RPL14,RPS14,RPL35,RPS20,RPS25,RPL27A |
1.546e-10 | -22.59 | MEPCE (methylphosphate capping enzyme) | protein interactions | 56257 | 839 | 16 | 19454 | 50 |
RPL8,RPL12,RPL18A,RPS3A,RPL36A,RPL13A,RPL37A,RPS20,RPS26,RPS14,RPL14,RPL35,RPL34,NTRK1,RPL27A,RPS25 |
1.546e-10 | -22.59 | NCL (nucleolin) | protein interactions | 4691 | 708 | 15 | 19454 | 50 |
PTPN6,RPS26,NTRK1,RPL27A,RPS25,RPL35,RPL14,RPS14,RPS3A,RPL13A,RPL8,RPL12,RPL18A,RPS20,RPL37A |
1.752e-10 | -22.47 | RPS3A (ribosomal protein S3A) | protein interactions | 6189 | 593 | 14 | 19454 | 50 |
RPL14,RPS14,RPL35,RPL34,RPL27A,NTRK1,RPS25,RPS26,RPL37A,RPS20,RPL8,RPL18A,RPL12,RPL13A |
2.546e-10 | -22.09 | ZC3H18 (zinc finger CCCH-type containing 18) | protein interactions | 124245 | 868 | 16 | 19454 | 50 |
RPL37A,RPS20,RPL8,RPL12,RPL18A,RPS3A,RPL36A,RPL13A,RPS14,RPL14,RPL35,RPL34,NTRK1,RPL27A,RPS25,RPS26 |
2.639e-10 | -22.06 | TTF1 (transcription termination factor 1) | protein interactions | 7270 | 106 | 8 | 19454 | 50 |
RPS3A,RPL13A,RPL8,RPL18A,RPS14,RPL35,RPL37A,RPL14 |
2.856e-10 | -21.98 | HMGB2 (high mobility group box 2) | protein interactions | 3148 | 229 | 10 | 19454 | 50 |
RPS26,RPS3A,RPL8,RPS20,RPS25,NTRK1,RPL27A,RPL34,RPL35,RPL14 |
3.993e-10 | -21.64 | RPL29 (ribosomal protein L29) | protein interactions | 6159 | 237 | 10 | 19454 | 50 |
RPL12,RPL8,PTPN6,RPS26,RPS3A,RPL14,RPL37A,RPS20,RPS25,NTRK1 |
3.993e-10 | -21.64 | CEBPZ (CCAAT enhancer binding protein zeta) | protein interactions | 10153 | 237 | 10 | 19454 | 50 |
NTRK1,RPS20,RPS14,RPL35,RPL37A,RPL14,RPL13A,RPL8,SYK,RPL18A |
4.093e-10 | -21.62 | KIF20A (kinesin family member 20A) | protein interactions | 10112 | 1044 | 17 | 19454 | 50 |
RPL36A,RPL13A,RPS3A,RPL18A,RPL12,RPL8,RPS20,CARD10,SPECC1,RPL37A,RPS26,GNAI2,RPL27A,RPL34,RPL35,RPS14,RPL14 |
4.549e-10 | -21.51 | SRP9 (signal recognition particle 9) | protein interactions | 6726 | 416 | 12 | 19454 | 50 |
RPL37A,RPS20,RPL8,RPL13A,RPS3A,RPL34,RPL35,RPL14,RPS25,RPL27A,RPS26,CD74 |
5.301e-10 | -21.36 | RPS21 (ribosomal protein S21) | protein interactions | 6227 | 244 | 10 | 19454 | 50 |
RPS25,RPS20,RPL34,RPL14,RPL37A,RPS14,RPS26,RPS3A,RPL12,RPL18A |
5.301e-10 | -21.36 | DDX31 (DEAD-box helicase 31) | protein interactions | 64794 | 244 | 10 | 19454 | 50 |
RPL8,RPL18A,RPS3A,RPL13A,RPL37A,RPL35,RPL14,RPS14,NTRK1,RPL27A |
5.355e-10 | -21.35 | RPL31 (ribosomal protein L31) | protein interactions | 6160 | 646 | 14 | 19454 | 50 |
RPS26,RPL14,RPL35,RPS14,RPL34,RPL27A,RPS25,RPL8,RPL12,RPL18A,RPS3A,RPL13A,RPL37A,RPS20 |
5.652e-10 | -21.29 | PDZD8 (PDZ domain containing 8) | protein interactions | 118987 | 424 | 12 | 19454 | 50 |
RPS25,RPL27A,RPL34,RPL35,RPS26,RPS20,RPL37A,RPL13A,RPS3A,RPL12,RPL18A,RPL8 |
5.963e-10 | -21.24 | RPL26L1 (ribosomal protein L26 like 1) | protein interactions | 51121 | 426 | 12 | 19454 | 50 |
RPL27A,RPL35,RPL14,RPS14,RPL34,RPS26,RPL37A,RPS3A,RPL13A,RPL8,RPL18A,RPL12 |
7.930e-10 | -20.96 | LARP7 (La ribonucleoprotein 7, transcriptional regulator) | protein interactions | 51574 | 1090 | 17 | 19454 | 50 |
RPS3A,RPL36A,RPL13A,RPL8,RPL18A,RPL12,RPS20,RPL37A,RPS26,HCK,NTRK1,RPL27A,RPS25,RPS14,RPL35,RPL14,RPL34 |
8.155e-10 | -20.93 | PHB1 (prohibitin 1) | protein interactions | 5245 | 1092 | 17 | 19454 | 50 |
RPL18A,RPL12,RPL8,RPL13A,RPS3A,RPL37A,CTSS,RPS20,CD74,RPS26,RPL34,RPS14,RPL14,RPL35,RPS25,NTRK1,RPL27A |
8.668e-10 | -20.87 | KIF14 (kinesin family member 14) | protein interactions | 9928 | 1803 | 21 | 19454 | 50 |
GNAI2,HCK,RPS26,RPL14,RPS14,RPL35,BMP2K,RPL34,RPL27A,NTRK1,PDZRN3,RPL8,RPL18A,RPL12,RPS3A,RBM47,RPL13A,RPL36A,RPL37A,SPECC1,RPS20 |
9.113e-10 | -20.82 | RIOK1 (RIO kinase 1) | protein interactions | 83732 | 552 | 13 | 19454 | 50 |
RPS14,RPL35,RPL14,RPS25,RPL27A,NTRK1,RPS20,RPL18A,RPL12,RPL8,RPL13A,RPL36A,RPS3A |
9.300e-10 | -20.80 | HMGB1 (high mobility group box 1) | protein interactions | 3146 | 443 | 12 | 19454 | 50 |
RPS25,RPL27A,NTRK1,RPL35,RPL14,RPS14,RPS20,RPL13A,RPS3A,RPL18A,RPL12,RPL8 |
9.647e-10 | -20.76 | RC3H1 (ring finger and CCCH-type domains 1) | protein interactions | 149041 | 676 | 14 | 19454 | 50 |
RPL27A,RPS25,RPS14,RPL14,RPL35,RPS3A,RPL36A,RPL13A,RBM47,RPL8,RPL12,RPL18A,RPS20,RPL37A |
9.833e-10 | -20.74 | RPS16 (ribosomal protein S16) | protein interactions | 6217 | 677 | 14 | 19454 | 50 |
RPL14,RPS14,RPL35,RPL34,RPL27A,RPS25,RPS26,RPL37A,RPS20,RPL8,RPL18A,RPL12,RPS3A,RPL13A |
1.030e-09 | -20.69 | Disease | REACTOME pathways | R-HSA-1643685 | 858 | 18 | 10285 | 41 |
RPL13A,RPS26,RPL8,RPS20,RPL12,RPL18A,ELMO1,RPL36A,RPL37A,HCK,RPL14,RPS14,RPS3A,RPL27A,GAB1,RPL35,RPL34,RPS25 |
1.091e-09 | -20.64 | RPL26 (ribosomal protein L26) | protein interactions | 6154 | 350 | 11 | 19454 | 50 |
PTPN6,RPS26,RPL13A,RPS3A,RPL8,RPS25,RPL34,RPL14,RPL37A,RPL35,RPS14 |
1.121e-09 | -20.61 | SNRNP70 (small nuclear ribonucleoprotein U1 subunit 70) | protein interactions | 6625 | 961 | 16 | 19454 | 50 |
RPS20,RPL37A,RPS3A,RPL36A,RPL13A,RPL8,RPL12,RPL18A,NTRK1,RPL27A,RPS25,RPS14,RPL35,RPL14,RPL34,RPS26 |
1.211e-09 | -20.53 | RNF113A (ring finger protein 113A) | protein interactions | 7737 | 688 | 14 | 19454 | 50 |
RPL37A,RPS20,RPL12,RPL18A,RPL8,RPL36A,RPL13A,RPS3A,RPL34,RPL14,RPS14,RPL35,RPL27A,RPS26 |
1.410e-09 | -20.38 | WWP2 (WW domain containing E3 ubiquitin protein ligase 2) | protein interactions | 11060 | 831 | 15 | 19454 | 50 |
RPL12,RPL18A,RPL8,RPL36A,RPL13A,RPS3A,RPL34,RPL35,RPL14,RPS14,RPL37A,RPS20,RPS25,NTRK1,RPL27A |
1.450e-09 | -20.35 | structural molecule activity | molecular function | GO:0005198 | 793 | 15 | 18094 | 49 |
RPS3A,RPL14,RPS25,RPL36A,RPS14,RPL34,RPL27A,RPS20,RPS26,RPL12,RPL18A,RPL35,RPL37A,RPL13A,RPL8 |
1.626e-09 | -20.24 | ACE2 (angiotensin converting enzyme 2) | protein interactions | 59272 | 986 | 16 | 19454 | 50 |
RPS20,RPL37A,RPL13A,RPL36A,RPS3A,RPL18A,RPL12,RPL8,RPS25,RPL27A,RPL34,RPL35,RPS14,RPL14,RPS26,GNAI2 |
1.773e-09 | -20.15 | VCAM1 (vascular cell adhesion molecule 1) | protein interactions | 7412 | 469 | 12 | 19454 | 50 |
RPS3A,ARAP1,RPL13A,RPL8,RPL12,SYK,RPL27A,RPS20,RPS25,RPS14,RPL14,RPL35 |
1.830e-09 | -20.12 | CYLD (CYLD lysine 63 deubiquitinase) | protein interactions | 1540 | 847 | 15 | 19454 | 50 |
RPL34,RPL14,RPS14,RPL35,RPS25,RPL27A,IVNS1ABP,RPS26,RPL37A,RPS20,RPL18A,RPL12,RPL8,RPL13A,RPS3A |
1.865e-09 | -20.10 | EIF5 (eukaryotic translation initiation factor 5) | protein interactions | 1983 | 200 | 9 | 19454 | 50 |
RPS14,RPL35,RPS25,RPS20,RPL27A,NTRK1,RPL13A,RPS26,RPS3A |
1.905e-09 | -20.08 | DDX6 (DEAD-box helicase 6) | protein interactions | 1656 | 472 | 12 | 19454 | 50 |
RPL34,RPS14,RPL35,RPS25,NTRK1,RPL27A,RPS26,RPL37A,RPS20,RPL8,RPL13A,RPS3A |
2.083e-09 | -19.99 | RPS19 (ribosomal protein S19) | protein interactions | 6223 | 591 | 13 | 19454 | 50 |
RPS25,RPL27A,RPS14,RPL35,RPL14,RPS26,RPS20,RPL37A,RPL13A,RPS3A,RPL12,RPL18A,RPL8 |
2.288e-09 | -19.90 | ILF3 (interleukin enhancer binding factor 3) | protein interactions | 3609 | 861 | 15 | 19454 | 50 |
IVNS1ABP,RPS26,RPS14,RPL14,RPL35,RPS25,NTRK1,RPL27A,RPL18A,RPL12,RPL8,RPL13A,RPS3A,RPL37A,RPS20 |
2.632e-09 | -19.76 | Srp72 (signal recognition particle 72) | protein interactions | 66661 | 208 | 9 | 19454 | 50 |
RPL27A,RPS25,RPS14,RPL14,RPS3A,RPL13A,RPL36A,RPL8,RPL18A |
2.686e-09 | -19.74 | RBM39 (RNA binding motif protein 39) | protein interactions | 9584 | 1021 | 16 | 19454 | 50 |
RPS26,RPL34,RPL35,RPS14,RPL14,RPS25,NTRK1,RPL27A,RPL18A,RPL12,RPL8,RPL36A,RPL13A,RPS3A,RPL37A,RPS20 |
2.837e-09 | -19.68 | RPS24 (ribosomal protein S24) | protein interactions | 6229 | 489 | 12 | 19454 | 50 |
RPL8,RPL18A,RPL12,RPS3A,RPS26,RPL35,RPS14,RPL14,RPL37A,DCC,RPS20,RPS25 |
2.837e-09 | -19.68 | PSPC1 (paraspeckle component 1) | protein interactions | 55269 | 489 | 12 | 19454 | 50 |
RPS3A,RPL13A,RPS26,RPL8,NTRK1,RPL27A,RPS20,RPS25,RPS14,RPL14,RPL35,RPL34 |
3.040e-09 | -19.61 | Prkab1 (protein kinase AMP-activated non-catalytic subunit beta 1) | protein interactions | 83803 | 90 | 7 | 19454 | 50 |
RPL34,RPS14,RPL37A,RPS25,RPL18A,RPL12,RPL8 |
3.542e-09 | -19.46 | RPL36AL (ribosomal protein L36a like) | protein interactions | 6166 | 297 | 10 | 19454 | 50 |
RPL35,RPL14,RPS14,RPL37A,RPL27A,RPL8,RPL18A,PTPN6,RPL36A,RPL13A |
3.982e-09 | -19.34 | KAT6A (lysine acetyltransferase 6A) | protein interactions | 7994 | 504 | 12 | 19454 | 50 |
RPS25,RPL27A,RPL34,RPL14,RPS14,RPS20,RPL36A,RPL13A,RPS3A,RPL18A,RPL12,RPL8 |
4.133e-09 | -19.30 | Prkaa1 (protein kinase AMP-activated catalytic subunit alpha 1) | protein interactions | 65248 | 94 | 7 | 19454 | 50 |
RPL34,RPL12,RPL18A,RPL8,RPL37A,RPS14,RPS25 |
4.406e-09 | -19.24 | PCBP1 (poly(rC) binding protein 1) | protein interactions | 5093 | 629 | 13 | 19454 | 50 |
RPS20,RPL18A,RPL12,RPL8,RPL13A,RBM47,RPS3A,RPL14,RPS14,RPS25,RPL27A,NTRK1,RPS26 |
4.845e-09 | -19.15 | RPF2 (ribosome production factor 2 homolog) | protein interactions | 84154 | 223 | 9 | 19454 | 50 |
RPL8,PTPN6,RPL13A,RPS3A,RPL37A,RPL14,RPS14,RPL35,CTSS |
5.295e-09 | -19.06 | INS (insulin) | protein interactions | 3630 | 517 | 12 | 19454 | 50 |
RPS14,RPL37A,RPL27A,RPS20,RPS25,RPL8,RPL18A,RPL12,SYK,RPS3A,RBM47,RPS26 |
5.880e-09 | -18.95 | IGSF8 (immunoglobulin superfamily member 8) | protein interactions | 93185 | 228 | 9 | 19454 | 50 |
RPL8,RPL12,RPS3A,ITM2B,RPL13A,RPL35,RPS14,RPL27A,RPS25 |
7.589e-09 | -18.70 | MEN1 (menin 1) | protein interactions | 4221 | 794 | 14 | 19454 | 50 |
RPS26,RPL34,RPL14,RPS14,RPL35,RPS25,RPL18A,RPL12,RPL8,RPL36A,RPL13A,RPS3A,RPL37A,RPS20 |
8.429e-09 | -18.59 | ITGA4 (integrin subunit alpha 4) | protein interactions | 3676 | 539 | 12 | 19454 | 50 |
RPL14,RPL35,RPS14,RPL27A,RPS25,SYK,ADAM28,RPS20,RPL8,RPL12,RPS3A,RPL13A |
8.958e-09 | -18.53 | RASA1 (RAS p21 protein activator 1) | protein interactions | 5921 | 165 | 8 | 19454 | 50 |
IVNS1ABP,SYK,HCK,CSF1R,NTRK1,PDE6D,DCC,GAB1 |
9.393e-09 | -18.48 | MAP3K14 (mitogen-activated protein kinase kinase kinase 14) | protein interactions | 9020 | 166 | 8 | 19454 | 50 |
RPL34,RPL14,RPL37A,RPS26,RPL13A,RPL36A,RPL18A,RPL8 |
9.808e-09 | -18.44 | NPM1 (nucleophosmin 1) | protein interactions | 4869 | 1118 | 16 | 19454 | 50 |
RPL13A,PSAP,RPS3A,RPL18A,RPL8,RPS20,RPL37A,RPS26,GNAI2,RPS25,RPL27A,NTRK1,RPL34,RPL14,RPS14,RPL35 |
9.831e-09 | -18.44 | PRC1 (protein regulator of cytokinesis 1) | protein interactions | 9055 | 959 | 15 | 19454 | 50 |
RPS20,RPL37A,SPECC1,RPS3A,RPL13A,RPL8,RPL18A,RPL12,RPL27A,RPL35,RPL14,RPS14,RPL34,RPS26,GNAI2 |
1.017e-08 | -18.40 | ribonucleoprotein complex | cellular component | GO:1990904 | 1101 | 16 | 19108 | 50 |
RPL8,RPL12,RPL27A,RPL37A,RPS3A,RPS20,RPL14,RPL18A,RPS26,RPL36A,RPL35,IVNS1ABP,RPS25,RPL13A,RPS14,RPL34 |
1.101e-08 | -18.32 | RPL28 (ribosomal protein L28) | protein interactions | 6158 | 437 | 11 | 19454 | 50 |
RPL18A,RPL8,RPS3A,DCC,RPL37A,PTPN6,RPL34,RPL35,RPS14,RPL14,RPS25 |
1.151e-08 | -18.28 | RBM28 (RNA binding motif protein 28) | protein interactions | 55131 | 336 | 10 | 19454 | 50 |
RPS3A,RPL13A,PTPN6,RPL8,SYK,RPL18A,NTRK1,RPS14,RPL14,RPL37A |
1.240e-08 | -18.21 | DDX21 (DExD-box helicase 21) | protein interactions | 9188 | 686 | 13 | 19454 | 50 |
RPS20,RPL37A,RPS3A,RPL13A,RPL8,RPL18A,RPL27A,NTRK1,RPL14,RPL35,RPL34,RPS26,IVNS1ABP |
1.315e-08 | -18.15 | BAP1 (BRCA1 associated protein 1) | protein interactions | 8314 | 1313 | 17 | 19454 | 50 |
RPL37A,RPS20,RPL8,RPL12,RPL18A,PSAP,RPS3A,RPL13A,RPL36A,RPS14,RPL14,RPL35,RPL34,RPL27A,RPS25,IVNS1ABP,RPS26 |
1.696e-08 | -17.89 | C7orf50 (chromosome 7 open reading frame 50) | protein interactions | 84310 | 179 | 8 | 19454 | 50 |
PTPN6,RPL13A,NTRK1,RPL18A,RPL37A,RPL35,RPL14,RPL8 |
1.706e-08 | -17.89 | RIN3 (Ras and Rab interactor 3) | protein interactions | 79890 | 456 | 11 | 19454 | 50 |
IVNS1ABP,RPL18A,RPL12,RPS3A,RPL36A,RPL13A,RPS14,RPL14,RPL35,RPL27A,RPS25 |
1.770e-08 | -17.85 | CAND1 (cullin associated and neddylation dissociated 1) | protein interactions | 55832 | 849 | 14 | 19454 | 50 |
RPS20,RPS25,NTRK1,RPL27A,RPL34,RPL35,RPS14,RPL14,RPL37A,RPL13A,RPS3A,RPL18A,RPL12,RPL8 |
1.795e-08 | -17.84 | DDX24 (DEAD-box helicase 24) | protein interactions | 57062 | 577 | 12 | 19454 | 50 |
SYK,RPS25,RPL27A,NTRK1,RPS14,RPL14,RPL35,RPL13A,RPS3A,RPL18A,RPL8,RPL37A |
1.956e-08 | -17.75 | N (nucleocapsid phosphoprotein) | protein interactions | 43740575 | 1174 | 16 | 19454 | 50 |
RPS26,IVNS1ABP,RPL27A,RPS25,RPL14,RPS14,RPL35,RPL34,RPS3A,RPL13A,RBM47,RPL8,RPL12,RPL18A,RPS20,RPL37A |
2.100e-08 | -17.68 | UFL1 (UFM1 specific ligase 1) | protein interactions | 23376 | 1015 | 15 | 19454 | 50 |
RPS3A,RPL13A,RPL8,IVNS1ABP,RPL12,RPL18A,RPL27A,NTRK1,RPS25,RPS20,RPL14,RPL35,RPS14,RPL37A,RPL34 |
2.549e-08 | -17.49 | CEP250 (centrosomal protein 250) | protein interactions | 11190 | 270 | 9 | 19454 | 50 |
RPL35,RPS14,RPL14,RPS25,RPL8,RPL18A,RPL12,RPS3A,RPL13A |
2.716e-08 | -17.42 | RPS28 (ribosomal protein S28) | protein interactions | 6234 | 272 | 9 | 19454 | 50 |
RPS14,RPL35,RPL37A,RPL14,RPS25,RPS20,RPL12,RPS3A,RPS26 |
3.134e-08 | -17.28 | PRPF8 (pre-mRNA processing factor 8) | protein interactions | 10594 | 742 | 13 | 19454 | 50 |
RPL37A,RPS20,RPL12,RPL18A,RPL8,RPL13A,RPS3A,RPL14,RPS14,RPS25,NTRK1,RPL27A,RPS26 |
3.156e-08 | -17.27 | NR2C2 (nuclear receptor subfamily 2 group C member 2) | protein interactions | 7182 | 1393 | 17 | 19454 | 50 |
RPL34,RPL14,RPS14,BMP2K,RPL35,RPS25,RPL27A,GNAI2,RPS26,RPL37A,RPS20,RPL18A,RPL12,RPL8,RPL36A,RPL13A,RPS3A |
3.499e-08 | -17.17 | CHD3 (chromodomain helicase DNA binding protein 3) | protein interactions | 1107 | 749 | 13 | 19454 | 50 |
RPL8,RPL12,RPL18A,RPS3A,RPL13A,RPS20,IVNS1ABP,HCK,RPS14,RPL14,RPL35,RPL27A,RPS25 |
3.573e-08 | -17.15 | RPF1 (ribosome production factor 1 homolog) | protein interactions | 80135 | 128 | 7 | 19454 | 50 |
RPL35,RPL37A,RPL14,RPL27A,RPL18A,RPL8,RPL13A |
3.843e-08 | -17.07 | SEC61B (SEC61 translocon subunit beta) | protein interactions | 10952 | 755 | 13 | 19454 | 50 |
RPL34,RPS14,RPL14,RPL35,RPS25,RPL27A,RPS26,RPS20,RPL18A,RPL12,RPL8,RPL13A,RPS3A |
3.869e-08 | -17.07 | RPL7L1 (ribosomal protein L7 like 1) | protein interactions | 285855 | 199 | 8 | 19454 | 50 |
PTPN6,RPL13A,RPS3A,RPL8,RPS14,RPL14,RPL37A,RPL35 |
4.181e-08 | -16.99 | TRIP4 (thyroid hormone receptor interactor 4) | protein interactions | 9325 | 201 | 8 | 19454 | 50 |
RPS20,RPL27A,NTRK1,RPL34,RPS14,RPL35,RXRA,RPL8 |
4.265e-08 | -16.97 | FTSJ3 (FtsJ RNA 2'-O-methyltransferase 3) | protein interactions | 117246 | 386 | 10 | 19454 | 50 |
RPL14,RPL37A,RPL35,RPL27A,NTRK1,RPL8,SYK,RPL18A,RPS3A,RPL13A |
4.464e-08 | -16.92 | TARDBP (TAR DNA binding protein) | protein interactions | 23435 | 501 | 11 | 19454 | 50 |
RPL35,RPS14,RPL14,RPS25,NTRK1,RPS20,RPL18A,RPL12,RPL8,RPL13A,RPS3A |
4.608e-08 | -16.89 | cytosol | cellular component | GO:0005829 | 5475 | 33 | 19108 | 50 |
RPS14,ARAP1,RPL34,RPS3A,RPS20,DIAPH2,RPS26,RPL35,IVNS1ABP,RPL36A,SH2B3,RPL12,RAPGEF6,GNAI2,FCHO2,SYK,RGL1,RPL37A,HCK,RPL8,RPL13A,RPS25,ELMO1,RPL14,RPL18A,DCC,RXRA,FYB1,RPL27A,SPECC1,PDE6D,PTPN6,GAB1 |
4.649e-08 | -16.88 | DHX30 (DExH-box helicase 30) | protein interactions | 22907 | 503 | 11 | 19454 | 50 |
NTRK1,RPS14,RPL35,RPL14,GNAI2,IVNS1ABP,RPL37A,RBM47,RPL13A,RPL18A,RPL8 |
4.657e-08 | -16.88 | ZBTB1 (zinc finger and BTB domain containing 1) | protein interactions | 22890 | 133 | 7 | 19454 | 50 |
RPL8,RPL13A,RPL34,RPL14,RPS14,RPS25,RPL27A |
4.904e-08 | -16.83 | TENT4B (terminal nucleotidyltransferase 4B) | protein interactions | 64282 | 134 | 7 | 19454 | 50 |
RPL13A,DIAPH2,RPL18A,RPL8,RPL37A,RPL14,RPL35 |
5.162e-08 | -16.78 | BMP4 (bone morphogenetic protein 4) | protein interactions | 652 | 135 | 7 | 19454 | 50 |
RPS3A,RPL18A,RPL12,RPL8,RPS20,RPL27A,RPL14 |
5.761e-08 | -16.67 | HNRNPU (heterogeneous nuclear ribonucleoprotein U) | protein interactions | 3192 | 933 | 14 | 19454 | 50 |
RPS25,NTRK1,RPL27A,RPL35,RPS14,RPS26,SYK,IVNS1ABP,RPL36A,RPL13A,RPS3A,RPL12,RPL18A,RPL8 |
6.119e-08 | -16.61 | DDX56 (DEAD-box helicase 56) | protein interactions | 54606 | 299 | 9 | 19454 | 50 |
RPL34,RPL35,RPL14,RPL37A,NTRK1,RPL18A,RPL8,RPL13A,RPS3A |
6.241e-08 | -16.59 | GTPBP4 (GTP binding protein 4) | protein interactions | 23560 | 402 | 10 | 19454 | 50 |
RPL13A,RPS3A,SYK,RPL18A,RPL8,NTRK1,RPL37A,RPL35,RPL14,RPS14 |
6.550e-08 | -16.54 | NSA2 (NSA2 ribosome biogenesis factor) | protein interactions | 10412 | 213 | 8 | 19454 | 50 |
RPS3A,RPL13A,RPL8,RPL18A,RPL14,RPS14,RPL37A,RPL35 |
6.724e-08 | -16.52 | FANCD2 (FA complementation group D2) | protein interactions | 2177 | 792 | 13 | 19454 | 50 |
RPL13A,RPS3A,RPL18A,RPL12,RPL8,RPS20,RPS26,GNAI2,RPS25,NTRK1,RPL14,RPL35,RPS14 |
6.749e-08 | -16.51 | AAR2 (AAR2 splicing factor) | protein interactions | 25980 | 651 | 12 | 19454 | 50 |
RPS3A,RPL13A,RPL8,RPL18A,RPL12,RPL27A,RPS20,RPS25,RPL14,RPL35,RPL37A,RPS14 |
6.855e-08 | -16.50 | EBNA1BP2 (EBNA1 binding protein 2) | protein interactions | 10969 | 303 | 9 | 19454 | 50 |
PTPN6,RPL13A,RPL8,RPL18A,SYK,RPL27A,RPL37A,RPL14,RPL34 |
6.874e-08 | -16.49 | CFTR (CF transmembrane conductance regulator) | protein interactions | 1080 | 1469 | 17 | 19454 | 50 |
RPL37A,SPECC1,RPS20,RPL8,RPL12,RPL18A,RPS3A,PSAP,RPL13A,RPS14,RPL14,RPL35,RPL34,RPL27A,RPS25,GNAI2,RPS26 |
7.312e-08 | -16.43 | PPAN-P2RY11 (PPAN-P2RY11 readthrough) | protein interactions | 692312 | 142 | 7 | 19454 | 50 |
RPL18A,RPL8,RPL13A,RPL35,RPS14,RPL37A,RPL14 |
7.667e-08 | -16.38 | EIF3B (eukaryotic translation initiation factor 3 subunit B) | protein interactions | 8662 | 307 | 9 | 19454 | 50 |
RPS3A,CD74,RPS26,RPL14,RPS14,NTRK1,RPL27A,RPS20,RPS25 |
8.400e-08 | -16.29 | NUDCD2 (NudC domain containing 2) | protein interactions | 134492 | 415 | 10 | 19454 | 50 |
RPS25,RPS20,RPL27A,RPS14,RPL35,RPL14,RPL13A,RPS3A,RPL12,RPL8 |
1.005e-07 | -16.11 | cytosolic small ribosomal subunit | cellular component | GO:0022627 | 44 | 5 | 19108 | 50 |
RPS14,RPS25,RPS20,RPS3A,RPS26 |
1.017e-07 | -16.10 | CHMP4C (charged multivesicular body protein 4C) | protein interactions | 92421 | 676 | 12 | 19454 | 50 |
RPL37A,RPS20,RPL18A,RPL8,RPL36A,RPL13A,RPS3A,RPL34,RPS14,RPL35,RPL14,RPL27A |
1.049e-07 | -16.07 | RANBP9 (RAN binding protein 9) | protein interactions | 10048 | 425 | 10 | 19454 | 50 |
NTRK1,RPS25,ENTPD1,RPL14,RPL34,RPL13A,RPL8,HIPK2,RPL12,RPL18A |
1.166e-07 | -15.96 | KLF4 (KLF transcription factor 4) | protein interactions | 9314 | 152 | 7 | 19454 | 50 |
RPL18A,RPS3A,RPL36A,RPL35,RPL14,RPL27A,RPS25 |
1.276e-07 | -15.87 | EBNA-LP (nuclear antigen EBNA-LP) | protein interactions | 3783746 | 154 | 7 | 19454 | 50 |
RPL8,RPS14,RPL12,RPL34,RPL27A,RPS3A,RPS25 |
1.310e-07 | -15.85 | CUL4B (cullin 4B) | protein interactions | 8450 | 692 | 12 | 19454 | 50 |
RPS20,RPS25,NTRK1,RPL27A,GAB1,RPS14,RPL35,RPL14,RPS26,RPL18A,RPL12,RPL8 |
1.333e-07 | -15.83 | SDAD1 (SDA1 domain containing 1) | protein interactions | 55153 | 155 | 7 | 19454 | 50 |
RPL13A,RPL36A,NTRK1,SYK,RPL18A,RPS14,RPL35 |
1.360e-07 | -15.81 | RIOX2 (ribosomal oxygenase 2) | protein interactions | 84864 | 93 | 6 | 19454 | 50 |
RPL13A,RPL18A,RPL8,RPL27A,RPL35,RPL14 |
1.363e-07 | -15.81 | KRAS (KRAS proto-oncogene, GTPase) | protein interactions | 3845 | 2876 | 23 | 19454 | 50 |
ITM2B,GNAI2,RPL27A,RPS25,RPL14,RPL35,RPS3A,RXRA,RPL13A,RPL8,RPL12,FCHO2,RPL18A,PDE6D,RPS20,RAPGEF6,SPECC1,RPS26,HCK,RPS14,RPL34,RPL37A,GAB1 |
1.408e-07 | -15.78 | KIF23 (kinesin family member 23) | protein interactions | 9493 | 1003 | 14 | 19454 | 50 |
RPS26,GNAI2,RPL27A,RPL35,RPS14,RPL14,RPL34,RPS3A,RPL13A,RPL8,RPL18A,RPL12,RPS20,SPECC1 |
1.541e-07 | -15.69 | FBXW7 (F-box and WD repeat domain containing 7) | protein interactions | 55294 | 1181 | 15 | 19454 | 50 |
RPL37A,RPS20,RPL8,RPL12,RPL18A,HIPK2,RPS3A,RPL13A,RPL14,RPS14,RPL35,RPL34,RPL27A,RPS25,RPS26 |
1.556e-07 | -15.68 | MYCN (MYCN proto-oncogene, bHLH transcription factor) | protein interactions | 4613 | 1363 | 16 | 19454 | 50 |
RPL14,RPL35,RPS14,RPL34,RPL27A,RPS25,GNAI2,RPS26,RPL37A,RPS20,RPL8,RPL12,RPL18A,RPS3A,RPL36A,RPL13A |
1.675e-07 | -15.60 | Rnf183 (ring finger protein 183) | protein interactions | 76072 | 447 | 10 | 19454 | 50 |
RPS20,RPS25,RPL34,RPS14,RPS26,RPL13A,RPS3A,RPL12,FCHO2,RPL8 |
1.683e-07 | -15.60 | TNIP1 (TNFAIP3 interacting protein 1) | protein interactions | 10318 | 1189 | 15 | 19454 | 50 |
RPS3A,RPL36A,RPL8,RPL12,RPS20,RPL37A,SPECC1,RPS26,RPL27A,RPS25,BMP2K,RPS14,RPL14,RPL35,RPL34 |
1.962e-07 | -15.44 | RPS10P5 (ribosomal protein S10 pseudogene 5) | protein interactions | 93144 | 51 | 5 | 19454 | 50 |
RPL37A,RPL14,RPL18A,RPS26,PTPN6 |
2.022e-07 | -15.41 | ECT2 (epithelial cell transforming 2) | protein interactions | 1894 | 871 | 13 | 19454 | 50 |
RBM47,RPL13A,RPS3A,RPL18A,RPL12,RPL8,RPS20,SPECC1,GNAI2,RPL34,RPS14,RPL35,RPL14 |
2.043e-07 | -15.40 | C8orf33 (chromosome 8 open reading frame 33) | protein interactions | 65265 | 165 | 7 | 19454 | 50 |
SYK,RPL34,RPL18A,RPL8,RPL14,PTPN6,RPS3A |
2.048e-07 | -15.40 | protein metabolic process | biological process | GO:0019538 | 3496 | 26 | 18204 | 50 |
RPS26,RPS14,RPS3A,RPL34,RPS20,RPS25,PTPN6,PDZRN3,CSF1R,ADAM28,RPL8,CD74,RPL13A,RPL37A,CTSS,HIPK2,RPL36A,HCK,RPL12,RPL18A,RPL35,NTRK1,RPL14,MAN1C1,RPL27A,SYK |
2.173e-07 | -15.34 | ICAM1 (intercellular adhesion molecule 1) | protein interactions | 3383 | 249 | 8 | 19454 | 50 |
RPS14,RPL35,RPL27A,RPS25,RPL8,RPL12,RPS3A,RPL13A |
2.227e-07 | -15.32 | USP14 (ubiquitin specific peptidase 14) | protein interactions | 9097 | 461 | 10 | 19454 | 50 |
RPS20,RPS25,NTRK1,RPL27A,RPL34,RPS14,RPL35,RPL13A,RPL12,HCK |
2.306e-07 | -15.28 | organonitrogen compound biosynthetic process | biological process | GO:1901566 | 1313 | 16 | 18204 | 50 |
RPL13A,RPL37A,RPL14,MAN1C1,RPL8,RPL27A,RPL35,RPL18A,RPL12,RPL34,RPS20,RPS25,RPS26,RPS14,RPS3A,RPL36A |
2.361e-07 | -15.26 | ZC3HAV1 (zinc finger CCCH-type containing, antiviral 1) | protein interactions | 56829 | 591 | 11 | 19454 | 50 |
RPS20,RPL37A,RPL13A,RPS3A,RPL12,RPL18A,RPL8,NTRK1,RPL35,RPL14,IVNS1ABP |
2.361e-07 | -15.26 | USP36 (ubiquitin specific peptidase 36) | protein interactions | 57602 | 591 | 11 | 19454 | 50 |
RPL34,RPL14,RPL37A,RPL27A,NTRK1,RPL18A,RPL12,RPL8,RPS26,RPL13A,RPL36A |
2.381e-07 | -15.25 | RRP8 (ribosomal RNA processing 8) | protein interactions | 23378 | 252 | 8 | 19454 | 50 |
RPS3A,RPL13A,RPL14,RPS14,RPL37A,RPL8,RPL18A,SYK |
2.446e-07 | -15.22 | GNL2 (G protein nucleolar 2) | protein interactions | 29889 | 352 | 9 | 19454 | 50 |
NTRK1,RPL35,RPL14,RPL37A,RPL13A,RPS3A,RPL18A,SYK,RPL8 |
2.749e-07 | -15.11 | DDRGK1 (DDRGK domain containing 1) | protein interactions | 65992 | 1235 | 15 | 19454 | 50 |
RPL34,RPS14,RPL14,RPL35,RPS25,RPL27A,RPS26,SPECC1,RPL37A,RPS20,RPL12,RPL18A,RPL8,RPL13A,RPS3A |
2.765e-07 | -15.10 | REXO4 (REX4 homolog, 3'-5' exonuclease) | protein interactions | 57109 | 257 | 8 | 19454 | 50 |
RPL35,RPL37A,RPL14,RPS14,RPL13A,RPS3A,RPL18A,RPL8 |
2.765e-07 | -15.10 | NPM3 (nucleophosmin/nucleoplasmin 3) | protein interactions | 10360 | 257 | 8 | 19454 | 50 |
RPL37A,RPL14,RPL34,RPS20,RPL8,RPL12,RPS3A,RPL13A |
2.799e-07 | -15.09 | cell junction | cellular component | GO:0030054 | 2224 | 20 | 19108 | 50 |
RPL14,RPS20,CADPS2,RPS3A,DCC,RPS26,RPS14,RPS25,RPL13A,PDZRN3,RPL34,PTPN6,RPL8,GAB1,GNAI2,FCHO2,FYB1,RPL12,HCK,RPL37A |
2.816e-07 | -15.08 | AURKB (aurora kinase B) | protein interactions | 9212 | 743 | 12 | 19454 | 50 |
RPL27A,RPS25,RPS20,RPS14,RPL35,RPL14,RPL34,RPS3A,RPL13A,RPL8,RPL18A,RPL12 |
2.848e-07 | -15.07 | RPS6KB2 (ribosomal protein S6 kinase B2) | protein interactions | 6199 | 258 | 8 | 19454 | 50 |
RPS26,RPS3A,RPL12,SYK,RPL8,RPS25,RPS14,RPL14 |
2.968e-07 | -15.03 | TAF1C (TATA-box binding protein associated factor, RNA polymerase I subunit C) | protein interactions | 9013 | 106 | 6 | 19454 | 50 |
RPL18A,RPL14,RPS14,RPL37A,RPL8,RPL13A |
3.019e-07 | -15.01 | HEXIM1 (HEXIM P-TEFb complex subunit 1) | protein interactions | 10614 | 902 | 13 | 19454 | 50 |
RPS20,HIPK2,RPL12,RPL8,RPL36A,RPS3A,RPL14,RPL35,RPS14,RPS25,RPL27A,HCK,RPS26 |
3.339e-07 | -14.91 | CCNF (cyclin F) | protein interactions | 899 | 2063 | 19 | 19454 | 50 |
RAPGEF6,RPL37A,RPS20,FCHO2,RPL12,RPL18A,RPL8,RPL36A,RPL13A,RPS3A,RPL34,RPL14,RPS14,RPL35,RPS25,RPL27A,GNAI2,ARAP1,RPS26 |
3.396e-07 | -14.90 | TUBG1 (tubulin gamma 1) | protein interactions | 7283 | 366 | 9 | 19454 | 50 |
SYK,RPL18A,RPL13A,RPS3A,RPS14,RPL14,RPS25,CTSS,NTRK1 |
3.552e-07 | -14.85 | DDX10 (DEAD-box helicase 10) | protein interactions | 1662 | 179 | 7 | 19454 | 50 |
RPL13A,RPL18A,RPL8,NTRK1,RPL37A,RPL35,RPL14 |
3.803e-07 | -14.78 | CNBP (CCHC-type zinc finger nucleic acid binding protein) | protein interactions | 7555 | 268 | 8 | 19454 | 50 |
RPS3A,RPL13A,RPL8,RPL18A,RPL12,RPL14,RPL37A,RPL34 |
3.865e-07 | -14.77 | PABPC1 (poly(A) binding protein cytoplasmic 1) | protein interactions | 26986 | 621 | 11 | 19454 | 50 |
RPL18A,RBM47,RPL13A,RPS3A,GAB1,RPL37A,RPS20,RPL14,RPL35,RPL27A,NTRK1 |
4.054e-07 | -14.72 | TRIM37 (tripartite motif containing 37) | protein interactions | 4591 | 624 | 11 | 19454 | 50 |
RPS20,RPL8,RPL18A,RPL12,RPS3A,RPL13A,RPL35,RPS14,RPL14,RPS25,RPS26 |
4.125e-07 | -14.70 | RPS27L (ribosomal protein S27 like) | protein interactions | 51065 | 183 | 7 | 19454 | 50 |
RPS25,RPS20,RPL27A,RPS3A,RPL12,RPL37A,RPL14 |
4.498e-07 | -14.61 | NOC2L (NOC2 like nucleolar associated transcriptional repressor) | protein interactions | 26155 | 274 | 8 | 19454 | 50 |
NTRK1,CTSS,RPS14,RPL35,RPL13A,RPL8,RPL18A,SYK |
4.641e-07 | -14.58 | cytoplasm | cellular component | GO:0005737 | 12081 | 47 | 19108 | 50 |
PDZRN3,ARAP1,RPS14,RPL35,IVNS1ABP,RPS3A,CADPS2,DIAPH2,RPL37A,HCK,RPL12,RPL8,ADAM28,RPS25,RPL13A,NTRK1,CD74,RXRA,DCC,ELMO1,RPL14,RPL27A,SPECC1,PTPN6,RPL34,CTSS,MAN1C1,RPS26,RPL36A,RPS20,RGL1,SYK,RAPGEF6,SH2B3,FCHO2,GNAI2,CARD10,RPL18A,ITGAX,HIPK2,PDE6D,RBM47,FYB1,PSAP,BMP2K,GAB1,ITM2B |
4.710e-07 | -14.57 | HSPA8 (heat shock protein family A (Hsp70) member 8) | protein interactions | 3312 | 2109 | 19 | 19454 | 50 |
RPS26,HCK,IVNS1ABP,GNAI2,RPS25,NTRK1,RPL27A,RPL34,RPS14,RPL35,RPL36A,RPL13A,RPS3A,PSAP,RPL12,RPL18A,RPL8,RPS20,RAPGEF6 |
4.726e-07 | -14.56 | EZH2 (enhancer of zeste 2 polycomb repressive complex 2 subunit) | protein interactions | 2146 | 1479 | 16 | 19454 | 50 |
RPL12,RPL18A,RPL8,RPL36A,RPL13A,RPS3A,RPL37A,RPS20,GNAI2,RPS26,RPL34,RPL35,RPS14,RPL14,RPS25,RPL27A |
4.755e-07 | -14.56 | GRWD1 (glutamate rich WD repeat containing 1) | protein interactions | 83743 | 381 | 9 | 19454 | 50 |
RPL27A,RPL34,RPL14,RPL37A,RPL13A,RPS3A,RPL18A,RPL12,RPL8 |
5.292e-07 | -14.45 | CCAT1 (colon cancer associated transcript 1) | protein interactions | 100507056 | 62 | 5 | 19454 | 50 |
RPL8,RPL35,RPL27A,RPS3A,RPS25 |
5.419e-07 | -14.43 | NDN (necdin, MAGE family member) | protein interactions | 4692 | 387 | 9 | 19454 | 50 |
RPL34,RPS14,RPL37A,RPL27A,RPL18A,RPL8,RPL13A,RPS26,RPS3A |
5.899e-07 | -14.34 | NOP53 (NOP53 ribosome biogenesis factor) | protein interactions | 29997 | 284 | 8 | 19454 | 50 |
RPL8,RPL18A,SYK,RPS3A,RPL13A,RPL35,RPL37A,RPL14 |
6.029e-07 | -14.32 | DOT1L (DOT1 like histone lysine methyltransferase) | protein interactions | 84444 | 798 | 12 | 19454 | 50 |
RPL8,GNAI2,RPL12,RPL18A,RPL36A,RPL13A,RPS26,RPL35,RPL34,NTRK1,RPS20,RPS25 |
6.161e-07 | -14.30 | RPS27A (ribosomal protein S27a) | protein interactions | 6233 | 393 | 9 | 19454 | 50 |
RPL18A,RPS26,RPL13A,RBM47,RPS3A,GAB1,RPL14,RPL35,RPL37A |
6.220e-07 | -14.29 | RBM34 (RNA binding motif protein 34) | protein interactions | 23029 | 286 | 8 | 19454 | 50 |
RPL14,RPL35,RPL37A,RPL13A,RPS3A,RPL18A,SYK,RPL8 |
6.357e-07 | -14.27 | nef (Nef) | protein interactions | 156110 | 802 | 12 | 19454 | 50 |
GNAI2,HCK,SYK,CD74,RPL14,ELMO1,ITGAX,CSF1R,RPL8,PSAP,RXRA,RPS20 |
6.782e-07 | -14.20 | CCDC137 (coiled-coil domain containing 137) | protein interactions | 339230 | 197 | 7 | 19454 | 50 |
RPL13A,RPL18A,RPL8,RPS14,RPL35,RPL14,RPL37A |
6.827e-07 | -14.20 | STAU1 (staufen double-stranded RNA binding protein 1) | protein interactions | 6780 | 1520 | 16 | 19454 | 50 |
RPL36A,RPL13A,RPS3A,RPL18A,RPL12,RPL8,RPL37A,IVNS1ABP,RPS25,NTRK1,RPL27A,RPL34,RPS14,BMP2K,RPL14,RPL35 |
7.253e-07 | -14.14 | KIN (Kin17 DNA and RNA binding protein) | protein interactions | 22944 | 66 | 5 | 19454 | 50 |
RPL14,RPL8,RPL12,RPL18A,RPL27A |
7.446e-07 | -14.11 | BIRC3 (baculoviral IAP repeat containing 3) | protein interactions | 330 | 1335 | 15 | 19454 | 50 |
RPL35,RPS14,RPL14,RPS25,RPL27A,RPS26,ITM2B,RPL37A,RPS20,RPL12,RPL18A,RPL8,RPL13A,RPL36A,RPS3A |
8.058e-07 | -14.03 | PTK2 (protein tyrosine kinase 2) | protein interactions | 5747 | 296 | 8 | 19454 | 50 |
NTRK1,RPL14,DCC,RPL34,PTPN6,SYK,HCK,RPL18A |
8.241e-07 | -14.01 | PAK1IP1 (PAK1 interacting protein 1) | protein interactions | 55003 | 126 | 6 | 19454 | 50 |
RPL18A,RPL8,RPL13A,RPL37A,RPL14,RPL35 |
8.302e-07 | -14.00 | SFN (stratifin) | protein interactions | 2810 | 671 | 11 | 19454 | 50 |
RPL8,RPS3A,SPECC1,RAPGEF6,GAB1,RPS20,RPL35,RPL34,NTRK1,RPL27A,RPS25 |
8.402e-07 | -13.99 | CUL5 (cullin 5) | protein interactions | 8065 | 533 | 10 | 19454 | 50 |
RPS20,RPS25,NTRK1,RPL27A,RPL35,RPS14,RPL13A,RPS3A,RPL12,RPL8 |
9.134e-07 | -13.91 | FN1 (fibronectin 1) | protein interactions | 2335 | 830 | 12 | 19454 | 50 |
RPL13A,RPS3A,RPL12,RPL8,RPS20,RPS26,RPS25,RPL27A,RPL14,RPS14,RPL35,BMP2K |
9.154e-07 | -13.90 | NOC3L (NOC3 like DNA replication regulator) | protein interactions | 64318 | 206 | 7 | 19454 | 50 |
NTRK1,RPL13A,RPL14,RPL35,RPL37A,RPL8,RPL18A |
9.354e-07 | -13.88 | ANLN (anillin, actin binding protein) | protein interactions | 54443 | 1763 | 17 | 19454 | 50 |
RPS20,SPECC1,RPS3A,RPL13A,RPL8,RPL18A,RPL12,RPL27A,RPS25,BMP2K,RPS14,RPL35,RPL14,RPL34,RPS26,GNAI2,HCK |
9.747e-07 | -13.84 | INPP5D (inositol polyphosphate-5-phosphatase D) | protein interactions | 3635 | 70 | 5 | 19454 | 50 |
HCK,GAB1,SYK,ARAP1,CSF1R |
9.846e-07 | -13.83 | RRP1B (ribosomal RNA processing 1B) | protein interactions | 23076 | 304 | 8 | 19454 | 50 |
SYK,RPL18A,RPL8,RPL13A,PTPN6,RPL35,RPL14,NTRK1 |
1.003e-06 | -13.81 | peptidyl-tyrosine phosphorylation | biological process | GO:0018108 | 66 | 5 | 18204 | 50 |
PTPN6,SYK,NTRK1,CSF1R,HCK |
1.116e-06 | -13.71 | METTL14 (methyltransferase 14, N6-adenosine-methyltransferase non-catalytic subunit) | protein interactions | 57721 | 550 | 10 | 19454 | 50 |
RPS3A,RPS26,GNAI2,RPL8,RPL12,RPL18A,RPS25,RPL35,RPL14,RPS14 |
1.165e-06 | -13.66 | peptidyl-tyrosine modification | biological process | GO:0018212 | 68 | 5 | 18204 | 50 |
HCK,CSF1R,NTRK1,SYK,PTPN6 |
1.181e-06 | -13.65 | NCK1 (NCK adaptor protein 1) | protein interactions | 4690 | 214 | 7 | 19454 | 50 |
ARAP1,IVNS1ABP,SYK,RPL12,NTRK1,GAB1,DCC |
1.231e-06 | -13.61 | NOP56 (NOP56 ribonucleoprotein) | protein interactions | 10528 | 556 | 10 | 19454 | 50 |
RPS3A,RPL13A,RPL8,RPL18A,RPL12,RPL27A,RPS25,RPL14,RPL37A,RPS14 |
1.257e-06 | -13.59 | STAU2 (staufen double-stranded RNA binding protein 2) | protein interactions | 27067 | 216 | 7 | 19454 | 50 |
RPL35,RPL14,RPL37A,RPS3A,RPL13A,RBM47,RPL8 |
1.310e-06 | -13.55 | CHMP4B (charged multivesicular body protein 4B) | protein interactions | 128866 | 703 | 11 | 19454 | 50 |
GNAI2,RPS14,RPL14,RPL35,RPL27A,RPL12,RPL18A,HIPK2,RPL8,RPS3A,SPECC1 |
1.358e-06 | -13.51 | RECQL4 (RecQ like helicase 4) | protein interactions | 9401 | 1400 | 15 | 19454 | 50 |
RPL8,RPL12,RPL18A,RPS3A,RPL13A,RPL36A,RPL37A,RPS20,RPS26,RPS14,RPL35,RPL14,RPL34,RPL27A,RPS25 |
1.377e-06 | -13.50 | GZF1 (GDNF inducible zinc finger protein 1) | protein interactions | 64412 | 75 | 5 | 19454 | 50 |
RPL18A,RPL8,RPL14,RPL13A,RPL27A |
1.405e-06 | -13.48 | VRK3 (VRK serine/threonine kinase 3) | protein interactions | 51231 | 138 | 6 | 19454 | 50 |
RPL12,RPL18A,RPS3A,RPL14,RPS14,RPS20 |
1.480e-06 | -13.42 | DDX18 (DEAD-box helicase 18) | protein interactions | 8886 | 321 | 8 | 19454 | 50 |
RPL18A,SYK,RPS14,RPL35,RPL14,RPL8,RPL13A,NTRK1 |
1.555e-06 | -13.37 | H3C6 (H3 clustered histone 6) | protein interactions | 8353 | 223 | 7 | 19454 | 50 |
RPS26,RPS20,RPL27A,RPS14,RPL37A,RPL14,RPL35 |
1.572e-06 | -13.36 | SSB (small RNA binding exonuclease protection factor La) | protein interactions | 6741 | 440 | 9 | 19454 | 50 |
RPL13A,RPS26,RPS3A,RPS20,RPS25,NTRK1,RPL27A,RPL14,RPL35 |
1.586e-06 | -13.35 | NAP1L1 (nucleosome assembly protein 1 like 1) | protein interactions | 4673 | 324 | 8 | 19454 | 50 |
RPL14,RPL37A,RPL27A,NTRK1,RPL8,RPL12,RPS3A,RPL36A |
1.680e-06 | -13.30 | CIT (citron rho-interacting serine/threonine kinase) | protein interactions | 11113 | 1424 | 15 | 19454 | 50 |
RPS20,SPECC1,RPS3A,RPL13A,RBM47,RPL8,RPL18A,RPL12,RPL27A,RPS25,RPL35,RPL14,RPS14,RPL34,RPS26 |
1.713e-06 | -13.28 | small ribosomal subunit | cellular component | GO:0015935 | 77 | 5 | 19108 | 50 |
RPS14,RPS20,RPS25,RPS3A,RPS26 |
1.744e-06 | -13.26 | PIH1D1 (PIH1 domain containing 1) | protein interactions | 55011 | 724 | 11 | 19454 | 50 |
RPL27A,RPS25,RPS14,RPL14,RPS26,RPS20,RPS3A,RPL13A,RPL8,RPL12,RPL18A |
1.770e-06 | -13.24 | MCM2 (minichromosome maintenance complex component 2) | protein interactions | 4171 | 1055 | 13 | 19454 | 50 |
RPL37A,RPS20,RPL18A,RPL12,RPS3A,RPL13A,RPS14,RPL34,RPL27A,NTRK1,RPS25,IVNS1ABP,RPS26 |
1.803e-06 | -13.23 | Ksr1 (kinase suppressor of ras 1) | protein interactions | 16706 | 228 | 7 | 19454 | 50 |
RPS14,RPL27A,RPS20,RPL8,RPL18A,RPL12,RPS3A |
1.856e-06 | -13.20 | GLYR1 (glyoxylate reductase 1 homolog) | protein interactions | 84656 | 229 | 7 | 19454 | 50 |
RPS3A,RPL13A,RPL8,RPL18A,RPL37A,RPL35,RPL14 |
1.866e-06 | -13.19 | COPS5 (COP9 signalosome subunit 5) | protein interactions | 10987 | 1060 | 13 | 19454 | 50 |
PDE6D,RPS20,RPL37A,RPS3A,RPL18A,RPL12,RPL8,RPS25,RPL27A,NTRK1,RPL35,RPS14,RPL14 |
1.951e-06 | -13.15 | Formation of the ternary complex, and subsequently, the 43S complex | REACTOME pathways | R-HSA-72695 | 53 | 5 | 10285 | 41 |
RPS25,RPS14,RPS20,RPS3A,RPS26 |
2.012e-06 | -13.12 | CHD4 (chromodomain helicase DNA binding protein 4) | protein interactions | 1108 | 895 | 12 | 19454 | 50 |
HCK,RPL14,RPL35,RPS14,NTRK1,RPL27A,RPS25,RPL8,RPL18A,RPL12,RPS3A,RPS20 |
2.065e-06 | -13.09 | ESR1 (estrogen receptor 1) | protein interactions | 2099 | 2322 | 19 | 19454 | 50 |
RPL27A,RPL34,BMP2K,RPL14,RPS14,RPS26,ITM2B,PTPN6,GNAI2,RPS20,SPECC1,RPL37A,RPL13A,RPL36A,RPS3A,RXRA,RPL18A,RPL12,RPL8 |
2.301e-06 | -12.98 | BTRC (beta-transducin repeat containing E3 ubiquitin protein ligase) | protein interactions | 8945 | 745 | 11 | 19454 | 50 |
RPS26,RPS25,RPL27A,CSF1R,RPL14,RPL13A,RPS3A,HIPK2,RPL8,RPS20,RPL37A |
2.379e-06 | -12.95 | vesicle | cellular component | GO:0031982 | 4141 | 26 | 19108 | 50 |
RPL34,CTSS,ENTPD1,RPS25,RPS14,NTRK1,MAN1C1,CD74,RPS26,DIAPH2,RPS20,RPL14,RPS3A,ITGAX,CADPS2,HCK,RPL37A,PDE6D,SYK,FCHO2,GNAI2,RAPGEF6,RPL12,PSAP,PTPN6,ITM2B |
2.397e-06 | -12.94 | DHX57 (DExH-box helicase 57) | protein interactions | 90957 | 238 | 7 | 19454 | 50 |
CARD10,RPS14,RPS20,RPL27A,NTRK1,SYK,RPS3A |
2.492e-06 | -12.90 | EGFR (epidermal growth factor receptor) | protein interactions | 1956 | 3105 | 22 | 19454 | 50 |
RPL12,FCHO2,RPL18A,RPL8,RPL13A,RPS3A,GAB1,RPL37A,RPS20,HCK,SYK,GNAI2,PTPN6,RPS26,RPL34,RPL35,RPL14,RPS14,SH2B3,RPS25,NTRK1,RPL27A |
2.677e-06 | -12.83 | PAFAH1B1 (platelet activating factor acetylhydrolase 1b regulatory subunit 1) | protein interactions | 5048 | 242 | 7 | 19454 | 50 |
RPS14,RPL27A,NTRK1,RPS25,RPL12,RPL13A,RPL36A |
2.790e-06 | -12.79 | CDK2 (cyclin dependent kinase 2) | protein interactions | 1017 | 760 | 11 | 19454 | 50 |
RPL34,RPL14,BMP2K,RPL35,RPS14,RPS20,NTRK1,RPL27A,RPL12,RPL8,RPS3A |
2.867e-06 | -12.76 | NLRP7 (NLR family pyrin domain containing 7) | protein interactions | 199713 | 156 | 6 | 19454 | 50 |
RPL34,RPL37A,RPL35,RPL14,RPS3A,RPL18A |
2.875e-06 | -12.76 | EIF6 (eukaryotic translation initiation factor 6) | protein interactions | 3692 | 351 | 8 | 19454 | 50 |
RPL13A,RPL8,RPL12,RPL18A,NTRK1,RPL14,RPL37A,RPL34 |
2.995e-06 | -12.72 | AGR2 (anterior gradient 2, protein disulphide isomerase family member) | protein interactions | 10551 | 930 | 12 | 19454 | 50 |
RPS20,RPS25,RPL27A,RPL34,RPL14,RPL35,RPL37A,RPS14,RPL13A,RPL12,HCK,RPL8 |
2.999e-06 | -12.72 | DDX54 (DEAD-box helicase 54) | protein interactions | 79039 | 353 | 8 | 19454 | 50 |
RPL14,RPS14,RPL35,SYK,RPL18A,RPL8,RPL13A,PTPN6 |
3.133e-06 | -12.67 | TRIM25 (tripartite motif containing 25) | protein interactions | 7706 | 2387 | 19 | 19454 | 50 |
RPL8,HIPK2,RPL12,RPL18A,RXRA,RPS3A,RBM47,RPL13A,RPL37A,RAPGEF6,RPS20,RPS26,ARAP1,RPS14,RPL35,RPL14,RPL34,RPL27A,RPS25 |
3.147e-06 | -12.67 | ZNF512 (zinc finger protein 512) | protein interactions | 84450 | 248 | 7 | 19454 | 50 |
RPL14,RPL35,RPL37A,RPL8,RPL18A,RPS3A,RPL13A |
3.199e-06 | -12.65 | synapse | cellular component | GO:0045202 | 1473 | 15 | 19108 | 50 |
RPS14,RPL13A,RPS25,PDZRN3,RPL34,RPL14,RPS20,CADPS2,RPS3A,DCC,RPS26,GNAI2,FCHO2,RPL12,RPL8 |
3.597e-06 | -12.54 | SOS1 (SOS Ras/Rac guanine nucleotide exchange factor 1) | protein interactions | 6654 | 91 | 5 | 19454 | 50 |
GAB1,HCK,CSF1R,NTRK1,PTPN6 |
3.608e-06 | -12.53 | ADARB1 (adenosine deaminase RNA specific B1) | protein interactions | 104 | 487 | 9 | 19454 | 50 |
RPL13A,RPS26,RPS3A,RPL18A,RPL12,RPL8,RPL27A,RPL37A,RPL14 |
3.650e-06 | -12.52 | MAPT (microtubule associated protein tau) | protein interactions | 4137 | 948 | 12 | 19454 | 50 |
RPL18A,RPL12,RPS3A,RPS20,SYK,GNAI2,RPS26,RPL34,RPS14,RPL14,RPL35,RPL27A |
3.777e-06 | -12.49 | UBE2H (ubiquitin conjugating enzyme E2 H) | protein interactions | 7328 | 1950 | 17 | 19454 | 50 |
SPECC1,RPL37A,RPS20,RPL18A,RPL12,RPL8,RPL13A,RPL36A,RPS3A,RPL34,RPL35,RPS14,RPL14,RPS25,RPL27A,IVNS1ABP,RPS26 |
3.796e-06 | -12.48 | TAF1D (TATA-box binding protein associated factor, RNA polymerase I subunit D) | protein interactions | 79101 | 92 | 5 | 19454 | 50 |
RPL8,RPL14,RPS14,RPL18A,RPL13A |
3.829e-06 | -12.47 | MPHOSPH10 (M-phase phosphoprotein 10) | protein interactions | 10199 | 164 | 6 | 19454 | 50 |
RPL35,RPL14,RPL37A,RPL8,RPL18A,RPL13A |
3.921e-06 | -12.45 | SRSF6 (serine and arginine rich splicing factor 6) | protein interactions | 6431 | 492 | 9 | 19454 | 50 |
RPS14,RPL35,RPL37A,NTRK1,RPL12,RPL18A,RPL8,RPL13A,RPS3A |
3.951e-06 | -12.44 | Ribosomal scanning and start codon recognition | REACTOME pathways | R-HSA-72702 | 61 | 5 | 10285 | 41 |
RPS20,RPS14,RPS25,RPS3A,RPS26 |
3.966e-06 | -12.44 | RPS29 (ribosomal protein S29) | protein interactions | 6235 | 165 | 6 | 19454 | 50 |
RPS3A,RPS20,RPS26,RPS25,RPS14,RPL8 |
4.021e-06 | -12.42 | H1-8 (H1.8 linker histone) | protein interactions | 132243 | 42 | 4 | 19454 | 50 |
RPL13A,RPS14,RPL37A,RPL8 |
4.084e-06 | -12.41 | PLCG1 (phospholipase C gamma 1) | protein interactions | 5335 | 258 | 7 | 19454 | 50 |
PTPN6,SYK,HCK,NTRK1,SH2B3,CTSS,GAB1 |
4.106e-06 | -12.40 | INO80B (INO80 complex subunit B) | protein interactions | 83444 | 166 | 6 | 19454 | 50 |
RPL36A,RPS3A,RPL12,RPL18A,RPL8,RPL27A |
4.190e-06 | -12.38 | KNOP1 (lysine rich nucleolar protein 1) | protein interactions | 400506 | 259 | 7 | 19454 | 50 |
RPS3A,RPL13A,RPL8,RPL18A,RPL37A,RPL35,RPL14 |
4.243e-06 | -12.37 | gene expression | biological process | GO:0010467 | 2751 | 21 | 18204 | 50 |
RPL34,RPS25,RPS20,RBM47,RPS26,RPS14,HIPK2,RPS3A,RPL36A,RPL18A,RPL12,RPL8,RPL14,RPL27A,IVNS1ABP,RPL35,RPL37A,RPL13A,CTSS,RXRA,CD74 |
4.285e-06 | -12.36 | Translation initiation complex formation | REACTOME pathways | R-HSA-72649 | 62 | 5 | 10285 | 41 |
RPS26,RPS3A,RPS20,RPS14,RPS25 |
4.447e-06 | -12.32 | PSTPIP1 (proline-serine-threonine phosphatase interacting protein 1) | protein interactions | 9051 | 95 | 5 | 19454 | 50 |
RPL36A,RPL34,RPL18A,RPL37A,RPL35 |
4.510e-06 | -12.31 | G3BP1 (G3BP stress granule assembly factor 1) | protein interactions | 10146 | 799 | 11 | 19454 | 50 |
RPS26,RPS3A,RPL12,RPL8,RPS25,RPS20,RPL27A,NTRK1,RPL34,RPL35,RPL14 |
4.641e-06 | -12.28 | Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S | REACTOME pathways | R-HSA-72662 | 63 | 5 | 10285 | 41 |
RPS26,RPS3A,RPS20,RPS25,RPS14 |
4.922e-06 | -12.22 | NAA40 (N-alpha-acetyltransferase 40, NatD catalytic subunit) | protein interactions | 79829 | 976 | 12 | 19454 | 50 |
RPL34,RPL35,RPL14,RPL27A,RPL12,RPL18A,RPL8,RPL13A,RPL36A,RPS3A,RAPGEF6,RPS20 |
5.566e-06 | -12.10 | GPC1 (glypican 1) | protein interactions | 2817 | 175 | 6 | 19454 | 50 |
RPL14,RPL12,PSAP,RPL27A,RPS20,RPS25 |
6.137e-06 | -12.00 | API5 (apoptosis inhibitor 5) | protein interactions | 8539 | 178 | 6 | 19454 | 50 |
RPL12,RPL8,RPL35,RPL13A,NTRK1,RPS3A |
7.269e-06 | -11.83 | RSL24D1 (ribosomal L24 domain containing 1) | protein interactions | 51187 | 105 | 5 | 19454 | 50 |
RPL8,RPL14,RPL37A,RPL35,RPL13A |
7.513e-06 | -11.80 | LOXL2 (lysyl oxidase like 2) | protein interactions | 4017 | 400 | 8 | 19454 | 50 |
RPL34,RPL35,RPS14,RPS25,RPS20,RPL27A,RPL8,RPS26 |
7.614e-06 | -11.79 | BUD13 (BUD13 homolog) | protein interactions | 84811 | 106 | 5 | 19454 | 50 |
RPL37A,RPL14,RPS14,RPL8,RPL13A |
7.934e-06 | -11.74 | CAPZA2 (capping actin protein of muscle Z-line subunit alpha 2) | protein interactions | 830 | 403 | 8 | 19454 | 50 |
FCHO2,RPL18A,GNAI2,ARAP1,SPECC1,CARD10,BMP2K,RPS20 |
8.343e-06 | -11.69 | IMP4 (IMP U3 small nucleolar ribonucleoprotein 4) | protein interactions | 92856 | 108 | 5 | 19454 | 50 |
RPL18A,RPL8,RPL14,RPL37A,RPL13A |
8.526e-06 | -11.67 | SURF6 (surfeit 6) | protein interactions | 6838 | 407 | 8 | 19454 | 50 |
RPL14,RPL35,RPL37A,RPL13A,RPS3A,RPL18A,SYK,RPL8 |
8.916e-06 | -11.63 | LTV1 (LTV1 ribosome biogenesis factor) | protein interactions | 84946 | 190 | 6 | 19454 | 50 |
NTRK1,RPS20,RPS14,RPL35,RPS3A,SYK |
9.038e-06 | -11.61 | HSPA1A (heat shock protein family A (Hsp70) member 1A) | protein interactions | 3303 | 1423 | 14 | 19454 | 50 |
SLC13A1,RPS3A,RPL13A,HIPK2,RPL12,RPL18A,RPS20,RAPGEF6,GAB1,RPS26,GNAI2,HCK,RPL27A,NTRK1 |
9.125e-06 | -11.60 | ZNF22 (zinc finger protein 22) | protein interactions | 7570 | 110 | 5 | 19454 | 50 |
RPS3A,RPL13A,RPL14,RPL37A,RPL18A |
9.125e-06 | -11.60 | KIT (KIT proto-oncogene, receptor tyrosine kinase) | protein interactions | 3815 | 110 | 5 | 19454 | 50 |
SH2B3,PTPN6,CSF1R,SYK,HCK |
9.182e-06 | -11.60 | CD81 (CD81 molecule) | protein interactions | 975 | 292 | 7 | 19454 | 50 |
RPL12,GNAI2,RPS3A,RPS14,RPL35,RPS25,RPL27A |
9.182e-06 | -11.60 | BRIX1 (biogenesis of ribosomes BRX1) | protein interactions | 55299 | 292 | 7 | 19454 | 50 |
PTPN6,RPL13A,RPL8,RPL18A,NTRK1,RPL37A,RPL14 |
9.441e-06 | -11.57 | RIT1 (Ras like without CAAX 1) | protein interactions | 6016 | 1229 | 13 | 19454 | 50 |
RPS3A,RPL18A,RPL12,RPL8,RPS20,RPL37A,RPS26,RPS25,RPL27A,RPL34,RGL1,RPL35,RPS14 |
9.465e-06 | -11.57 | YTHDC2 (YTH N6-methyladenosine RNA binding protein C2) | protein interactions | 64848 | 192 | 6 | 19454 | 50 |
RPL13A,NTRK1,RPL18A,RPS14,RPL14,RPL8 |
9.864e-06 | -11.53 | BRCA1 (BRCA1 DNA repair associated) | protein interactions | 672 | 1234 | 13 | 19454 | 50 |
CTSS,RPL37A,RPS3A,PSAP,RPL8,RPL12,RPL18A,RPL27A,RPS25,RPL35,RPS14,RPL14,RPL34 |
1.035e-05 | -11.48 | MYBBP1A (MYB binding protein 1a) | protein interactions | 10514 | 418 | 8 | 19454 | 50 |
RPL37A,RPL35,RPL14,RPS14,NTRK1,RPL18A,RPL8,RPL13A |
1.111e-05 | -11.41 | LCP2 (lymphocyte cytosolic protein 2) | protein interactions | 3937 | 54 | 4 | 19454 | 50 |
PTPN6,SYK,HCK,FYB1 |
1.118e-05 | -11.40 | LYN (LYN proto-oncogene, Src family tyrosine kinase) | protein interactions | 4067 | 713 | 10 | 19454 | 50 |
RPS3A,PTPN6,HCK,SYK,FCHO2,NTRK1,CSF1R,RPS20,SPECC1,GAB1 |
1.148e-05 | -11.38 | PABPC4 (poly(A) binding protein cytoplasmic 4) | protein interactions | 8761 | 424 | 8 | 19454 | 50 |
RPS3A,RPL13A,RBM47,IVNS1ABP,RPL8,RPL18A,NTRK1,RPS20 |
1.187e-05 | -11.34 | TFCP2 (transcription factor CP2) | protein interactions | 7024 | 426 | 8 | 19454 | 50 |
RPS25,RPL27A,RPL14,RPS14,RPS26,RPS3A,RPL12,GNAI2 |
1.195e-05 | -11.34 | CUL2 (cullin 2) | protein interactions | 8453 | 565 | 9 | 19454 | 50 |
RPS3A,RPL8,RPL12,NTRK1,RPL27A,RPS20,RPS25,RPS14,RPL14 |
1.239e-05 | -11.30 | macromolecule biosynthetic process | biological process | GO:0009059 | 3197 | 22 | 18204 | 50 |
RPS26,RBM47,RPL36A,RPS14,HIPK2,RPS3A,RPL34,RPS25,RPS20,RPL12,RPL18A,RPL35,IVNS1ABP,MAN1C1,RPL8,RPL14,RPL27A,RXRA,CD74,RPL37A,RPL13A,CTSS |
1.240e-05 | -11.30 | WDR5 (WD repeat domain 5) | protein interactions | 11091 | 1069 | 12 | 19454 | 50 |
RPL27A,NTRK1,RPL14,RPS14,RPL34,GNAI2,RPL37A,SPECC1,RPL13A,RPL8,RPL12,RPL18A |
1.244e-05 | -11.29 | SPDL1 (spindle apparatus coiled-coil protein 1) | protein interactions | 54908 | 306 | 7 | 19454 | 50 |
DIAPH2,RPL12,RPL27A,RPS25,RPS20,RPL35,RPS14 |
1.264e-05 | -11.28 | EBNA-1 (protein-coding) | protein interactions | 3783709 | 202 | 6 | 19454 | 50 |
SYK,RPL13A,RPS26,RPL35,SPECC1,RPL27A |
1.279e-05 | -11.27 | organonitrogen compound metabolic process | biological process | GO:1901564 | 4594 | 27 | 18204 | 50 |
RPL13A,RPL37A,CTSS,CD74,RPL8,PDZRN3,CSF1R,ADAM28,PTPN6,RPL34,RPS20,RPS25,RPS26,RPS14,RPS3A,SYK,RPL14,NTRK1,MAN1C1,RPL27A,RPL35,PSAP,RPL18A,HCK,RPL12,RPL36A,HIPK2 |
1.325e-05 | -11.23 | TSR1 (TSR1 ribosome maturation factor) | protein interactions | 55720 | 309 | 7 | 19454 | 50 |
SYK,RPS3A,RPS26,RPS14,NTRK1,RPS20,RPS25 |
1.338e-05 | -11.22 | ATG4B (autophagy related 4B cysteine peptidase) | protein interactions | 23192 | 119 | 5 | 19454 | 50 |
RPS3A,RPL13A,RPS25,RPS26,RPL34 |
1.355e-05 | -11.21 | NEK4 (NIMA related kinase 4) | protein interactions | 6787 | 574 | 9 | 19454 | 50 |
RPS25,RPS20,RPL27A,RPL34,RPS14,RPL35,RPL36A,RPL12,RPL8 |
1.374e-05 | -11.20 | SEC61A1 (SEC61 translocon subunit alpha 1) | protein interactions | 29927 | 205 | 6 | 19454 | 50 |
RPS14,RPL35,NTRK1,CTSS,SLC13A1,RPL13A |
1.374e-05 | -11.20 | CMTR1 (cap methyltransferase 1) | protein interactions | 23070 | 205 | 6 | 19454 | 50 |
RPL12,RPL18A,RPL35,RPL13A,RPS26,NTRK1 |
1.438e-05 | -11.15 | PTEN (phosphatase and tensin homolog) | protein interactions | 5728 | 734 | 10 | 19454 | 50 |
RPL13A,RPS26,GNAI2,RPL18A,RPL12,RPL27A,RPS20,RPS25,RPL14,RPL34 |
1.452e-05 | -11.14 | LARP1 (La ribonucleoprotein 1, translational regulator) | protein interactions | 23367 | 438 | 8 | 19454 | 50 |
SYK,IVNS1ABP,RBM47,RPS3A,RPL35,RPS14,RPS20,NTRK1 |
1.533e-05 | -11.09 | BMS1 (BMS1 ribosome biogenesis factor) | protein interactions | 9790 | 209 | 6 | 19454 | 50 |
RPS3A,RPL13A,RPS14,RPL35,RPL8,RPL18A |
1.575e-05 | -11.06 | DCAF1 (DDB1 and CUL4 associated factor 1) | protein interactions | 9730 | 210 | 6 | 19454 | 50 |
RPL14,RPL35,RPL18A,RPL27A,NTRK1,RPL13A |
1.597e-05 | -11.04 | SPRTN (SprT-like N-terminal domain) | protein interactions | 83932 | 586 | 9 | 19454 | 50 |
RPS26,RPS3A,RPL12,RPL8,RPS20,RPS25,RPL27A,RPS14,RPL37A |
1.696e-05 | -10.98 | Metabolism of proteins | REACTOME pathways | R-HSA-392499 | 1619 | 18 | 10285 | 41 |
RPL35,RPL34,RPS25,ITM2B,RPL27A,RPS3A,RPL14,GNAI2,RPS14,RPL36A,MAN1C1,RPL37A,RPL18A,RPS20,RPL8,RPL12,RPL13A,RPS26 |
1.848e-05 | -10.90 | H2AC21 (H2A clustered histone 21) | protein interactions | 317772 | 216 | 6 | 19454 | 50 |
RPS25,RPL35,RPL14,RPL37A,RPL13A,RPL8 |
1.879e-05 | -10.88 | SRSF5 (serine and arginine rich splicing factor 5) | protein interactions | 6430 | 454 | 8 | 19454 | 50 |
PTPN6,RPL13A,NTRK1,RPS3A,PSAP,RPL18A,RPL37A,RPL8 |
1.905e-05 | -10.87 | PYM1 (PYM homolog 1, exon junction complex associated factor) | protein interactions | 84305 | 128 | 5 | 19454 | 50 |
RPS26,RPS25,RPS20,RPS3A,RPS14 |
1.908e-05 | -10.87 | FZR1 (fizzy and cell division cycle 20 related 1) | protein interactions | 51343 | 1116 | 12 | 19454 | 50 |
RPL12,RPL18A,RPS3A,RPL13A,RPL37A,RPS20,RPS26,RPS14,RPL14,RPL35,RPL27A,RPS25 |
1.986e-05 | -10.83 | AATF (apoptosis antagonizing transcription factor) | protein interactions | 26574 | 329 | 7 | 19454 | 50 |
HIPK2,RPL8,RPL35,RPS25,RPL13A,RPS20,RPS3A |
2.057e-05 | -10.79 | FAM111A (FAM111 trypsin like peptidase A) | protein interactions | 63901 | 63 | 4 | 19454 | 50 |
RPL13A,RPL14,RPL35,RPL8 |
2.212e-05 | -10.72 | ZNF668 (zinc finger protein 668) | protein interactions | 79759 | 223 | 6 | 19454 | 50 |
RPL8,RPL14,RPL12,RPL18A,RPS3A,RPL13A |
2.266e-05 | -10.69 | RUFY1 (RUN and FYVE domain containing 1) | protein interactions | 80230 | 466 | 8 | 19454 | 50 |
RPS26,HCK,RPL12,RPL27A,NTRK1,RPS25,RPS20,RPS14 |
2.385e-05 | -10.64 | GPATCH4 (G-patch domain containing 4 (gene/pseudogene)) | protein interactions | 54865 | 226 | 6 | 19454 | 50 |
NTRK1,RPL37A,RPL14,RPL35,RPS3A,RPL18A |
2.499e-05 | -10.60 | UBA52 (ubiquitin A-52 residue ribosomal protein fusion product 1) | protein interactions | 7311 | 341 | 7 | 19454 | 50 |
RPL18A,RPS25,RPS20,RPL27A,RPL34,RPS14,RPL35 |
2.554e-05 | -10.58 | MYC (MYC proto-oncogene, bHLH transcription factor) | protein interactions | 4609 | 3018 | 20 | 19454 | 50 |
RPS3A,PSAP,RPL36A,RPL13A,RPL8,RPL12,RPL18A,RPS20,RPL37A,SPECC1,RPS26,GNAI2,HCK,NTRK1,RPL27A,RPS25,RPL14,RPL35,RPS14,RPL34 |
2.841e-05 | -10.47 | TOP2A (DNA topoisomerase II alpha) | protein interactions | 7153 | 481 | 8 | 19454 | 50 |
RPL8,RPL36A,RPS3A,RPL14,RPS14,RPL35,RPS20,RPL27A |
2.900e-05 | -10.45 | NKRF (NFKB repressing factor) | protein interactions | 55922 | 234 | 6 | 19454 | 50 |
RPL8,RPL13A,RPL35,RPL37A,RPL14,NTRK1 |
2.926e-05 | -10.44 | SPOP (speckle type BTB/POZ protein) | protein interactions | 8405 | 483 | 8 | 19454 | 50 |
RPS3A,RPS26,HIPK2,RPL27A,RPS25,RPL14,RPS14,RPL34 |
2.934e-05 | -10.44 | HEY1 (hes related family bHLH transcription factor with YRPW motif 1) | protein interactions | 23462 | 140 | 5 | 19454 | 50 |
RPS25,RPS20,RPL8,RPS14,RPL12 |
2.950e-05 | -10.43 | TRIM67 (tripartite motif containing 67) | protein interactions | 440730 | 4804 | 26 | 19454 | 50 |
PSAP,RPS3A,RPL13A,RPL36A,RPL8,RPL12,FCHO2,RPL18A,RPS20,DCC,SPECC1,RAPGEF6,GNAI2,RPL27A,RPS25,RPL14,BMP2K,RPL35,RPL37A,RPS26,DIAPH2,ARAP1,IVNS1ABP,RPS14,RPL34,ELMO1 |
3.078e-05 | -10.39 | RNF2 (ring finger protein 2) | protein interactions | 6045 | 802 | 10 | 19454 | 50 |
SPECC1,RPL34,RPL14,RPL27A,RPL18A,GNAI2,RBM47,RPL13A,RPS26,RPS3A |
3.116e-05 | -10.38 | WDR77 (WD repeat domain 77) | protein interactions | 79084 | 353 | 7 | 19454 | 50 |
RPS3A,RPS26,RPL13A,RPL8,NTRK1,RPS25,RPS14 |
3.124e-05 | -10.37 | RIOK3 (RIO kinase 3) | protein interactions | 8780 | 70 | 4 | 19454 | 50 |
RPS25,RPS26,RPS20,RPS3A |
3.304e-05 | -10.32 | Dnajc17 (DnaJ heat shock protein family (Hsp40) member C17) | protein interactions | 69408 | 71 | 4 | 19454 | 50 |
RPL13A,RPL12,RPL14,RPL35 |
3.348e-05 | -10.30 | EIF4B (eukaryotic translation initiation factor 4B) | protein interactions | 1975 | 357 | 7 | 19454 | 50 |
RPS14,RPL14,NTRK1,RPS20,RPS25,RPS3A,RPS26 |
3.419e-05 | -10.28 | BRD4 (bromodomain containing 4) | protein interactions | 23476 | 1601 | 14 | 19454 | 50 |
RPS20,RPL36A,RPL13A,RPS3A,RXRA,RPL18A,RPL12,RPL8,RPL27A,RPL34,RPS14,RPL35,RPL14,RPS26 |
3.811e-05 | -10.18 | RNA binding | molecular function | GO:0003723 | 1976 | 16 | 18094 | 49 |
RPL36A,RPL34,RPS14,RPL27A,RBM47,RPS3A,RPL14,RPS25,RPL12,RPL18A,RPL35,RPL37A,RPL8,RPL13A,RPS20,RPS26 |
3.830e-05 | -10.17 | ZNF48 (zinc finger protein 48) | protein interactions | 197407 | 148 | 5 | 19454 | 50 |
RPL8,RPL37A,RPL18A,RPL27A,RPL13A |
3.878e-05 | -10.16 | HUWE1 (HECT, UBA and WWE domain containing E3 ubiquitin protein ligase 1) | protein interactions | 10075 | 656 | 9 | 19454 | 50 |
RPL8,RPL12,RPS3A,CD74,RPL13A,RPS14,NTRK1,RPL27A,RPS25 |
4.007e-05 | -10.12 | protein tyrosine kinase activity | molecular function | GO:0004713 | 142 | 5 | 18094 | 49 |
NTRK1,HCK,SYK,CSF1R,HIPK2 |
4.105e-05 | -10.10 | EIF3E (eukaryotic translation initiation factor 3 subunit E) | protein interactions | 3646 | 249 | 6 | 19454 | 50 |
CD74,RPS3A,RPS20,RPS25,NTRK1,DCC |
4.198e-05 | -10.08 | Rpl35 (ribosomal protein L35) | protein interactions | 66489 | 250 | 6 | 19454 | 50 |
RPS3A,RPL27A,RPS25,RPL13A,RPS14,RPL18A |
4.212e-05 | -10.08 | MYH9 (myosin heavy chain 9) | protein interactions | 4627 | 663 | 9 | 19454 | 50 |
NTRK1,BMP2K,RPS14,SPECC1,RXRA,PTPN6,IVNS1ABP,GNAI2,FCHO2 |
4.215e-05 | -10.07 | NOL12 (nucleolar protein 12) | protein interactions | 79159 | 151 | 5 | 19454 | 50 |
RPL18A,RPL14,RPL8,RPL13A,RPS3A |
4.275e-05 | -10.06 | DKC1 (dyskerin pseudouridine synthase 1) | protein interactions | 1736 | 371 | 7 | 19454 | 50 |
NTRK1,RPL14,RPL35,RPL37A,RPL13A,RPL18A,RPL8 |
4.378e-05 | -10.04 | CUL7 (cullin 7) | protein interactions | 9820 | 836 | 10 | 19454 | 50 |
RPL12,RPL8,RPS26,CD74,RPS3A,RPL35,RPS14,RPL14,RPS25,RPL27A |
4.489e-05 | -10.01 | RSBN1 (round spermatid basic protein 1) | protein interactions | 54665 | 153 | 5 | 19454 | 50 |
RPL13A,RPL14,RPL35,RPL8,RPL18A |
4.529e-05 | -10.00 | EFTUD2 (elongation factor Tu GTP binding domain containing 2) | protein interactions | 9343 | 1425 | 13 | 19454 | 50 |
RPS20,RPS3A,RPL13A,RPL8,RPL12,RPL18A,NTRK1,RPL27A,RPS25,RPL14,RPS14,RPL35,RPS26 |
4.550e-05 | -10.00 | TAF1A (TATA-box binding protein associated factor, RNA polymerase I subunit A) | protein interactions | 9015 | 77 | 4 | 19454 | 50 |
RPL13A,RPL37A,RPL14,RPL8 |
4.870e-05 | -9.93 | SNAI1 (snail family transcriptional repressor 1) | protein interactions | 6615 | 519 | 8 | 19454 | 50 |
RPL8,IVNS1ABP,RPL12,RPL18A,RPS3A,RPL13A,RPL14,RPS14 |
4.924e-05 | -9.92 | MAK16 (MAK16 homolog) | protein interactions | 84549 | 156 | 5 | 19454 | 50 |
RPL8,RPL14,RPL35,RPS3A,RPL13A |
5.232e-05 | -9.86 | NGB (neuroglobin) | protein interactions | 58157 | 158 | 5 | 19454 | 50 |
RPS3A,RPL13A,RPL36A,GNAI2,RPL34 |
5.379e-05 | -9.83 | cellular biosynthetic process | biological process | GO:0044249 | 3776 | 23 | 18204 | 50 |
IVNS1ABP,RPL8,RXRA,CD74,RPL13A,RPL37A,CTSS,RPS26,RPS3A,RPS14,RPL34,RPS20,RPS25,RPL35,RPL14,MAN1C1,RPL27A,SYK,RBM47,RPL36A,HIPK2,RPL12,RPL18A |
5.621e-05 | -9.79 | HSPA5 (heat shock protein family A (Hsp70) member 5) | protein interactions | 3309 | 1455 | 13 | 19454 | 50 |
HCK,GNAI2,IVNS1ABP,RPL34,RPL35,RPL14,BMP2K,RPS25,NTRK1,RPL12,RPL8,RPS3A,RPS20 |
5.722e-05 | -9.77 | FNDC3B (fibronectin type III domain containing 3B) | protein interactions | 64778 | 161 | 5 | 19454 | 50 |
RPS3A,RBM47,RPS14,RPL34,RPL12 |
5.740e-05 | -9.77 | H4C1 (H4 clustered histone 1) | protein interactions | 8359 | 1678 | 14 | 19454 | 50 |
PTPN6,RPL27A,RPS25,RPL35,RPS14,RPL14,RPL34,RPS3A,RPL36A,RPL13A,RPL8,RPL18A,RPL12,RPS20 |
6.249e-05 | -9.68 | PIK3R1 (phosphoinositide-3-kinase regulatory subunit 1) | protein interactions | 5295 | 394 | 7 | 19454 | 50 |
RXRA,PTPN6,SYK,HCK,NTRK1,CSF1R,GAB1 |
6.249e-05 | -9.68 | RNF31 (ring finger protein 31) | protein interactions | 55072 | 394 | 7 | 19454 | 50 |
RPL34,RPL35,RPS14,RPS20,RPS25,NTRK1,IVNS1ABP |
6.390e-05 | -9.66 | Tyr_kinase_cat_dom | interpro domains | IPR020635 | 80 | 4 | 18521 | 50 |
HCK,SYK,NTRK1,CSF1R |
6.429e-05 | -9.65 | TUBGCP4 (tubulin gamma complex component 4) | protein interactions | 27229 | 165 | 5 | 19454 | 50 |
RPS3A,RPL36A,RPL14,RPL35,RPL18A |
6.483e-05 | -9.64 | YAP1 (Yes1 associated transcriptional regulator) | protein interactions | 10413 | 1064 | 11 | 19454 | 50 |
RPL13A,RPS26,RPS3A,RPL12,GNAI2,RPS25,RPL27A,RAPGEF6,GAB1,RPL14,RPS14 |
6.570e-05 | -9.63 | PPIE (peptidylprolyl isomerase E) | protein interactions | 10450 | 271 | 6 | 19454 | 50 |
SPECC1,RPL12,RPL8,RPS26,RPL27A,RPS3A |
6.658e-05 | -9.62 | NOP2 (NOP2 nucleolar protein) | protein interactions | 4839 | 398 | 7 | 19454 | 50 |
PTPN6,RPS3A,RPL18A,RPL8,NTRK1,RPL14,RPL37A |
6.802e-05 | -9.60 | Metabolism | REACTOME pathways | R-HSA-1430728 | 2158 | 20 | 10285 | 41 |
ENTPD1,RPL18A,RPL13A,RPS26,RXRA,PSAP,RGL1,RPS20,RPL8,RPL12,RPL27A,RPS3A,RPL34,RPL35,RPS25,RPL36A,RPL37A,RPL14,GNAI2,RPS14 |
6.826e-05 | -9.59 | CSF2RB (colony stimulating factor 2 receptor subunit beta) | protein interactions | 1439 | 31 | 3 | 19454 | 50 |
PTPN6,SYK,HCK |
7.096e-05 | -9.55 | cellular metabolic process | biological process | GO:0044237 | 5975 | 30 | 18204 | 50 |
RXRA,CD74,RPL13A,RPL37A,CTSS,IVNS1ABP,CSF1R,RPL8,ENTPD1,PTPN6,RPS26,RPS14,RPS3A,RPL34,RPS20,RPS25,SYK,RPL35,BMP2K,RPL14,NTRK1,MAN1C1,RPL27A,RPL12,HCK,PSAP,RPL18A,RBM47,RPL36A,HIPK2 |
7.124e-05 | -9.55 | GADD45GIP1 (GADD45G interacting protein 1) | protein interactions | 90480 | 275 | 6 | 19454 | 50 |
RPL27A,RPS3A,RPL13A,PTPN6,RPL35,CARD10 |
7.344e-05 | -9.52 | PLCG2 (phospholipase C gamma 2) | protein interactions | 5336 | 87 | 4 | 19454 | 50 |
PTPN6,SYK,GAB1,HCK |
7.614e-05 | -9.48 | MRPL3 (mitochondrial ribosomal protein L3) | protein interactions | 11222 | 171 | 5 | 19454 | 50 |
RPS14,RPL35,NTRK1,RBM47,RPL13A |
8.347e-05 | -9.39 | extracellular exosome | cellular component | GO:0070062 | 2175 | 16 | 19108 | 50 |
RPS20,RPL14,RPS3A,CD74,RPS26,ENTPD1,RPS25,RPS14,MAN1C1,RPL34,PTPN6,ITM2B,GNAI2,RPL12,PSAP,RPL37A |
8.522e-05 | -9.37 | LIN28A (lin-28 homolog A) | protein interactions | 79727 | 414 | 7 | 19454 | 50 |
RPL37A,RPL35,RPS14,RPS20,RPL8,RPS26,RPS3A |
8.725e-05 | -9.35 | NIP7 (nucleolar pre-rRNA processing protein NIP7) | protein interactions | 51388 | 176 | 5 | 19454 | 50 |
RPL18A,RPL8,RPL37A,RPL35,RPL14 |
8.754e-05 | -9.34 | SH2DOMAIN | prints domains | PR00401 | 72 | 4 | 5227 | 18 |
SH2B3,SYK,HCK,PTPN6 |
8.830e-05 | -9.33 | receptor complex | cellular component | GO:0043235 | 409 | 7 | 19108 | 50 |
PTPN6,ITGAX,RXRA,CD74,NTRK1,CSF1R,SYK |
8.961e-05 | -9.32 | SREK1 (splicing regulatory glutamic acid and lysine rich protein 1) | protein interactions | 140890 | 177 | 5 | 19454 | 50 |
NTRK1,RPS3A,RPL13A,RPL37A,RPL35 |
8.961e-05 | -9.32 | GRB7 (growth factor receptor bound protein 7) | protein interactions | 2886 | 177 | 5 | 19454 | 50 |
RPL37A,RPL14,RPL35,RPL12,RPL13A |
9.014e-05 | -9.31 | NAT10 (N-acetyltransferase 10) | protein interactions | 55226 | 287 | 6 | 19454 | 50 |
RPL35,RPS14,NTRK1,RPL18A,RPS3A,RPL13A |
9.203e-05 | -9.29 | BOP1 (BOP1 ribosomal biogenesis factor) | protein interactions | 23246 | 178 | 5 | 19454 | 50 |
SYK,RPL14,RPL35,RPL13A,NTRK1 |
9.203e-05 | -9.29 | DICER1 (dicer 1, ribonuclease III) | protein interactions | 23405 | 178 | 5 | 19454 | 50 |
RPL13A,NTRK1,RPL27A,RPL12,RPL18A |
9.321e-05 | -9.28 | hemopoiesis | biological process | GO:0030097 | 688 | 9 | 18204 | 50 |
CD74,SYK,PTPN6,SH2B3,RBM47,CSF1R,RPS14,HIPK2,NTRK1 |
9.462e-05 | -9.27 | NIFK (nucleolar protein interacting with the FHA domain of MKI67) | protein interactions | 84365 | 421 | 7 | 19454 | 50 |
RPL13A,RPS3A,RPL18A,RPL8,RPL37A,RPL35,RPL14 |
9.604e-05 | -9.25 | anchoring junction | cellular component | GO:0070161 | 902 | 10 | 19108 | 50 |
RPL8,GAB1,PTPN6,RPS3A,HCK,RPL37A,RPL13A,RPS14,RPL12,FYB1 |
9.956e-05 | -9.21 | DIMT1 (DIM1 rRNA methyltransferase and ribosome maturation factor) | protein interactions | 27292 | 181 | 5 | 19454 | 50 |
RPS25,RPS26,RPS20,PTPN6,RPL8 |
9.973e-05 | -9.21 | RPA1 (replication protein A1) | protein interactions | 6117 | 3034 | 19 | 19454 | 50 |
NTRK1,RPL27A,RPS25,RPL14,RPL35,RPS14,RPL34,ARAP1,RPS26,DIAPH2,RPS20,RPL37A,ADAM28,RAPGEF6,RPS3A,RPL13A,RPL8,RPL18A,RPL12 |
1.022e-04 | -9.19 | ASCC3 (activating signal cointegrator 1 complex subunit 3) | protein interactions | 10973 | 182 | 5 | 19454 | 50 |
ENTPD1,PTPN6,CD74,RPS20,NTRK1 |
1.029e-04 | -9.18 | CTNNB1 (catenin beta 1) | protein interactions | 1499 | 926 | 10 | 19454 | 50 |
RPS20,NTRK1,SPECC1,RPS14,PTPN6,RPS3A,RXRA,RPL12,RPL18A,RPL8 |
1.034e-04 | -9.18 | haematopoietic_and_lymphoid_tissue-haematopoietic_neoplasm-myelodysplastic_syndrome | COSMIC cancer mutations | haematopoietic_and_lymphoid_tissue-haematopoietic_neoplasm-myelodysplastic_syndrome | 1174 | 12 | 16828 | 49 |
DIAPH2,HCK,CADPS2,GAB1,HIPK2,NTRK1,SYK,BMP2K,CSF1R,SH2B3,DCC,PDZRN3 |
1.034e-04 | -9.18 | myelodysplastic_syndrome | COSMIC cancer mutations | myelodysplastic_syndrome | 1174 | 12 | 16828 | 49 |
NTRK1,HIPK2,GAB1,CADPS2,HCK,DIAPH2,PDZRN3,DCC,SH2B3,CSF1R,BMP2K,SYK |
1.078e-04 | -9.14 | EIF3CL (eukaryotic translation initiation factor 3 subunit C like) | protein interactions | 728689 | 96 | 4 | 19454 | 50 |
RPS20,RPS26,RPS3A,RPL35 |
1.143e-04 | -9.08 | RSL1D1 (ribosomal L1 domain containing 1) | protein interactions | 26156 | 434 | 7 | 19454 | 50 |
NTRK1,RPL35,RPS14,RPL13A,RPS3A,RPL18A,RPL8 |
1.154e-04 | -9.07 | focal adhesion | cellular component | GO:0005925 | 427 | 7 | 19108 | 50 |
HCK,RPL8,RPL37A,RPS14,RPL13A,RPS3A,RPL12 |
1.161e-04 | -9.06 | UTP23 (UTP23 small subunit processome component) | protein interactions | 84294 | 187 | 5 | 19454 | 50 |
RPL13A,RPS3A,RPL35,RPL37A,RPL8 |
1.167e-04 | -9.06 | RBMX2 (RNA binding motif protein X-linked 2) | protein interactions | 51634 | 98 | 4 | 19454 | 50 |
RPL8,RPL14,RPS14,RPL13A |
1.175e-04 | -9.05 | RA | pfam domains | PF00788 | 34 | 3 | 17795 | 50 |
RGL1,RAPGEF6,ARAP1 |
1.192e-04 | -9.04 | HP1BP3 (heterochromatin protein 1 binding protein 3) | protein interactions | 50809 | 302 | 6 | 19454 | 50 |
RPL14,RPL35,RPS14,NTRK1,SYK,RPL13A |
1.249e-04 | -8.99 | Tyr_kinase_AS | interpro domains | IPR008266 | 95 | 4 | 18521 | 50 |
HCK,SYK,NTRK1,CSF1R |
1.280e-04 | -8.96 | PRP4K (pre-mRNA processing factor kinase PRP4K) | protein interactions | 8899 | 306 | 6 | 19454 | 50 |
RPL13A,NTRK1,RPL18A,RPL8,RPS14,RPL14 |
1.282e-04 | -8.96 | FAU (FAU ubiquitin like and ribosomal protein S30 fusion) | protein interactions | 2197 | 191 | 5 | 19454 | 50 |
RPL12,RPL27A,RPS20,RPS26,RPS25 |
1.312e-04 | -8.94 | THAP12 (THAP domain containing 12) | protein interactions | 5612 | 101 | 4 | 19454 | 50 |
RPL8,RPL35,RPS14,RPL13A |
1.332e-04 | -8.92 | cell-substrate junction | cellular component | GO:0030055 | 437 | 7 | 19108 | 50 |
HCK,RPL37A,RPL13A,RPS14,RPL12,RPL8,RPS3A |
1.363e-04 | -8.90 | MATN2 (matrilin 2) | protein interactions | 4147 | 102 | 4 | 19454 | 50 |
RPL14,RPS14,RPL8,RPL34 |
1.379e-04 | -8.89 | TRMT1L (tRNA methyltransferase 1 like) | protein interactions | 81627 | 194 | 5 | 19454 | 50 |
RPL18A,SYK,RPL13A,NTRK1,RPL27A |
1.389e-04 | -8.88 | integrin-mediated signaling pathway | biological process | GO:0007229 | 96 | 4 | 18204 | 50 |
FYB1,SYK,ITGAX,HCK |
1.391e-04 | -8.88 | regulation of cytokine-mediated signaling pathway | biological process | GO:0001959 | 182 | 5 | 18204 | 50 |
SH2B3,RBM47,CD74,SYK,PTPN6 |
1.407e-04 | -8.87 | UBE2O (ubiquitin conjugating enzyme E2 O) | protein interactions | 63893 | 776 | 9 | 19454 | 50 |
IVNS1ABP,RPL8,RPS26,RPL37A,RPL35,RPS14,NTRK1,RPL27A,RPS20 |
1.451e-04 | -8.84 | extracellular vesicle | cellular component | GO:1903561 | 2278 | 16 | 19108 | 50 |
RPS26,CD74,RPL14,RPS20,RPS3A,RPL34,RPS14,RPS25,ENTPD1,MAN1C1,PTPN6,ITM2B,RPL37A,GNAI2,PSAP,RPL12 |
1.454e-04 | -8.84 | TyrKc | smart domains | SM00219 | 80 | 4 | 9717 | 33 |
NTRK1,HCK,SYK,CSF1R |
1.458e-04 | -8.83 | extracellular organelle | cellular component | GO:0043230 | 2279 | 16 | 19108 | 50 |
ITM2B,PTPN6,RPL37A,PSAP,RPL12,GNAI2,RPS26,CD74,RPS3A,RPL14,RPS20,RPL34,MAN1C1,RPS14,ENTPD1,RPS25 |
1.458e-04 | -8.83 | extracellular membrane-bounded organelle | cellular component | GO:0065010 | 2279 | 16 | 19108 | 50 |
RPS26,CD74,RPL14,RPS20,RPS3A,RPL34,RPS14,RPS25,ENTPD1,MAN1C1,PTPN6,ITM2B,RPL37A,GNAI2,PSAP,RPL12 |
1.464e-04 | -8.83 | macromolecule metabolic process | biological process | GO:0043170 | 5858 | 29 | 18204 | 50 |
RPS20,RPS25,RPL34,RPS14,RPS3A,RPS26,PTPN6,RPL8,ADAM28,CSF1R,PDZRN3,IVNS1ABP,CTSS,RPL13A,RPL37A,CD74,RXRA,HIPK2,RPL36A,RBM47,RPL18A,RPL12,HCK,RPL27A,RPL14,NTRK1,MAN1C1,RPL35,SYK |
1.481e-04 | -8.82 | MDM2 (MDM2 proto-oncogene) | protein interactions | 4193 | 609 | 8 | 19454 | 50 |
RPS25,RPS20,RPL37A,RPS14,RPS26,RPL36A,HCK,HIPK2 |
1.495e-04 | -8.81 | gag (Pr55(Gag)) | protein interactions | 155030 | 969 | 10 | 19454 | 50 |
RPL36A,SYK,IVNS1ABP,RPL8,ITGAX,RPL27A,RPL34,RPL14,RPL37A,RPL35 |
1.499e-04 | -8.81 | ZNF746 (zinc finger protein 746) | protein interactions | 155061 | 315 | 6 | 19454 | 50 |
RPL35,RPL14,RPL8,RPL34,RPL27A,RPL13A |
1.502e-04 | -8.80 | regulation of ERK1 and ERK2 cascade | biological process | GO:0070372 | 295 | 6 | 18204 | 50 |
CD74,CSF1R,PTPN6,SYK,NTRK1,GNAI2 |
1.579e-04 | -8.75 | EIF3A (eukaryotic translation initiation factor 3 subunit A) | protein interactions | 8661 | 318 | 6 | 19454 | 50 |
RPS3A,CD74,RPS26,NTRK1,RPS20,RPS25 |
1.580e-04 | -8.75 | RA_dom | interpro domains | IPR000159 | 39 | 3 | 18521 | 50 |
RAPGEF6,ARAP1,RGL1 |
1.590e-04 | -8.75 | LARP4 (La ribonucleoprotein 4) | protein interactions | 113251 | 200 | 5 | 19454 | 50 |
RBM47,RPS20,RPS3A,NTRK1,RPS14 |
1.602e-04 | -8.74 | EED (embryonic ectoderm development) | protein interactions | 8726 | 616 | 8 | 19454 | 50 |
RPL27A,RPL14,RPS14,RPS26,RPL13A,RPL8,RPL18A,RPL12 |
1.627e-04 | -8.72 | WDR36 (WD repeat domain 36) | protein interactions | 134430 | 201 | 5 | 19454 | 50 |
RPL18A,RPL35,RPL13A,NTRK1,RPL27A |
1.633e-04 | -8.72 | RPA3 (replication protein A3) | protein interactions | 6119 | 2870 | 18 | 19454 | 50 |
RPL35,RPS14,RPL14,RPL34,RPL27A,RPS25,GNAI2,RPS26,ADAM28,RPL37A,RAPGEF6,RPS20,RPL8,RPL18A,RPL12,RPS3A,RPL13A,RPL36A |
1.633e-04 | -8.72 | GNL3 (G protein nucleolar 3) | protein interactions | 26354 | 320 | 6 | 19454 | 50 |
NTRK1,RPS14,RPL14,RPL37A,SYK,RPL18A |
1.640e-04 | -8.72 | RPL39 (ribosomal protein L39) | protein interactions | 6170 | 107 | 4 | 19454 | 50 |
RPL37A,SYK,RPS3A,PTPN6 |
1.696e-04 | -8.68 | protein-containing complex | cellular component | GO:0032991 | 6542 | 30 | 19108 | 50 |
RPL12,GNAI2,SYK,RPL37A,RPL8,RPS14,RPL34,RPS3A,RPS20,RPS26,RPL35,IVNS1ABP,RPL36A,FYB1,RPL27A,SPECC1,RBM47,PTPN6,NTRK1,RPL13A,RPS25,CSF1R,CARD10,ITGAX,ELMO1,HIPK2,RPL14,CD74,RPL18A,RXRA |
1.709e-04 | -8.67 | postsynaptic density | cellular component | GO:0014069 | 317 | 6 | 19108 | 50 |
DCC,RPL8,RPL12,RPS25,RPS14,RPL14 |
1.718e-04 | -8.67 | TNF (tumor necrosis factor) | protein interactions | 7124 | 323 | 6 | 19454 | 50 |
RPL34,RPS25,RPS20,RPL12,RPL13A,RPS26 |
1.743e-04 | -8.65 | VAV1 (vav guanine nucleotide exchange factor 1) | protein interactions | 7409 | 204 | 5 | 19454 | 50 |
IVNS1ABP,HCK,SYK,GAB1,PTPN6 |
1.747e-04 | -8.65 | RPA2 (replication protein A2) | protein interactions | 6118 | 2885 | 18 | 19454 | 50 |
RPL34,RPL35,RPS14,RPL14,RPS25,RPL27A,GNAI2,RPS26,DIAPH2,RAPGEF6,RPL37A,ADAM28,RPS20,RPL12,RPL18A,RPL8,RPL13A,RPS3A |
1.750e-04 | -8.65 | SRC (SRC proto-oncogene, non-receptor tyrosine kinase) | protein interactions | 6714 | 624 | 8 | 19454 | 50 |
RXRA,PTPN6,SYK,HCK,FYB1,NTRK1,CSF1R,GAB1 |
1.761e-04 | -8.64 | MCTS1 (MCTS1 re-initiation and release factor) | protein interactions | 28985 | 109 | 4 | 19454 | 50 |
RPS25,RPS20,RPS3A,RPS14 |
1.761e-04 | -8.64 | EXOSC1 (exosome component 1) | protein interactions | 51013 | 109 | 4 | 19454 | 50 |
RPS20,RPS25,RPL27A,SYK |
1.773e-04 | -8.64 | SH2 | pfam domains | PF00017 | 100 | 4 | 17795 | 50 |
HCK,PTPN6,SH2B3,SYK |
1.773e-04 | -8.64 | H1-1 (H1.1 linker histone, cluster member) | protein interactions | 3024 | 466 | 7 | 19454 | 50 |
RPL37A,RPS20,RPL8,RPL18A,RPL12,RPS3A,RPS26 |
1.773e-04 | -8.64 | BAG1 (BAG cochaperone 1) | protein interactions | 573 | 466 | 7 | 19454 | 50 |
RPL8,RPL12,RPS3A,RPS26,RPL13A,RPS14,RPL37A |
1.824e-04 | -8.61 | CDK12 (cyclin dependent kinase 12) | protein interactions | 51755 | 206 | 5 | 19454 | 50 |
RPL37A,RPL14,RPS14,NTRK1,RPL13A |
1.828e-04 | -8.61 | RHOJ (ras homolog family member J) | protein interactions | 57381 | 628 | 8 | 19454 | 50 |
RPL34,SPECC1,GAB1,FCHO2,GNAI2,DIAPH2,RPL13A,ITM2B |
1.834e-04 | -8.60 | BLNK (B cell linker) | protein interactions | 29760 | 43 | 3 | 19454 | 50 |
SYK,GAB1,PTPN6 |
1.866e-04 | -8.59 | MRPL24 (mitochondrial ribosomal protein L24) | protein interactions | 79590 | 207 | 5 | 19454 | 50 |
RPL8,RPL35,RPL13A,RPL27A,NTRK1 |
1.866e-04 | -8.59 | RBM45 (RNA binding motif protein 45) | protein interactions | 129831 | 207 | 5 | 19454 | 50 |
RPS14,RPL8,RPS20,RBM47,RPS25 |
1.874e-04 | -8.58 | regulation of response to cytokine stimulus | biological process | GO:0060759 | 194 | 5 | 18204 | 50 |
CD74,RBM47,SH2B3,PTPN6,SYK |
1.888e-04 | -8.57 | CUL3 (cullin 3) | protein interactions | 8452 | 2633 | 17 | 19454 | 50 |
RPL12,RPL18A,RPL8,PDZRN3,RPL13A,RPS3A,PSAP,RPL37A,RPS20,RPS26,RPL34,RPL14,RPL35,RPS14,RPS25,NTRK1,RPL27A |
1.889e-04 | -8.57 | RSBN1L (round spermatid basic protein 1 like) | protein interactions | 222194 | 111 | 4 | 19454 | 50 |
RPL13A,NTRK1,RPL8,RPL14 |
1.908e-04 | -8.56 | MRPL15 (mitochondrial ribosomal protein L15) | protein interactions | 29088 | 208 | 5 | 19454 | 50 |
RPL13A,RBM47,NTRK1,RPS14,RPL35 |
1.951e-04 | -8.54 | NLE1 (notchless homolog 1) | protein interactions | 54475 | 209 | 5 | 19454 | 50 |
RPL14,RPS14,RPL27A,RPL13A,RPS25 |
2.023e-04 | -8.51 | NGDN (neuroguidin) | protein interactions | 25983 | 113 | 4 | 19454 | 50 |
RPS14,RPL18A,RPS3A,RPL13A |
2.039e-04 | -8.50 | CRKL (CRK like proto-oncogene, adaptor protein) | protein interactions | 1399 | 211 | 5 | 19454 | 50 |
ELMO1,GAB1,SYK,HCK,NTRK1 |
2.059e-04 | -8.49 | CLTA (clathrin light chain A) | protein interactions | 1211 | 334 | 6 | 19454 | 50 |
NTRK1,BMP2K,RPS14,RPL14,RPS26,FCHO2 |
2.093e-04 | -8.47 | PIAS1 (protein inhibitor of activated STAT 1) | protein interactions | 8554 | 335 | 6 | 19454 | 50 |
RPS3A,RPS25,RPS20,RPL14,RPS14,RPL35 |
2.101e-04 | -8.47 | EPOR (erythropoietin receptor) | protein interactions | 2057 | 45 | 3 | 19454 | 50 |
SYK,GAB1,PTPN6 |
2.122e-04 | -8.46 | SH2 | interpro domains | IPR000980 | 109 | 4 | 18521 | 50 |
SYK,HCK,PTPN6,SH2B3 |
2.164e-04 | -8.44 | CDH2 (cadherin 2) | protein interactions | 1000 | 115 | 4 | 19454 | 50 |
RPL14,RPL8,NTRK1,RPS26 |
2.164e-04 | -8.44 | MTF1 (metal regulatory transcription factor 1) | protein interactions | 4520 | 115 | 4 | 19454 | 50 |
RPS3A,RPL18A,RPL8,RPL14 |
2.225e-04 | -8.41 | ACO2 (aconitase 2) | protein interactions | 50 | 215 | 5 | 19454 | 50 |
RPS14,RPL12,NTRK1,RPS20,RPS26 |
2.231e-04 | -8.41 | asymmetric synapse | cellular component | GO:0032279 | 333 | 6 | 19108 | 50 |
RPS14,RPL14,RPS25,RPL12,RPL8,DCC |
2.237e-04 | -8.41 | CCDC140 (CCDC140 long non-coding RNA) | protein interactions | 151278 | 116 | 4 | 19454 | 50 |
RPL8,RPL14,RPL18A,RPL13A |
2.243e-04 | -8.40 | PPT2 (palmitoyl-protein thioesterase 2) | protein interactions | 9374 | 46 | 3 | 19454 | 50 |
RPL8,RPS26,RPS3A |
2.273e-04 | -8.39 | RBM19 (RNA binding motif protein 19) | protein interactions | 9904 | 216 | 5 | 19454 | 50 |
RPS3A,RBM47,RPL13A,RPS14,RPL35 |
2.304e-04 | -8.38 | KLRA1P (killer cell lectin like receptor A1, pseudogene) | protein interactions | 10748 | 9 | 2 | 19454 | 50 |
SYK,PTPN6 |
2.322e-04 | -8.37 | CDK7 (cyclin dependent kinase 7) | protein interactions | 1022 | 487 | 7 | 19454 | 50 |
RPL35,RPS14,RPS20,RPL12,RPL8,RPL13A,RPS3A |
2.423e-04 | -8.33 | KRI1 (KRI1 homolog) | protein interactions | 65095 | 219 | 5 | 19454 | 50 |
SYK,RPS14,RPL35,CTSS,RPL13A |
2.434e-04 | -8.32 | TUFM (Tu translation elongation factor, mitochondrial) | protein interactions | 7284 | 655 | 8 | 19454 | 50 |
GAB1,RPL37A,RPL14,RPS20,NTRK1,RPL12,RPL8,RPS26 |
2.437e-04 | -8.32 | SH2_dom_sf | interpro domains | IPR036860 | 113 | 4 | 18521 | 50 |
SYK,HCK,PTPN6,SH2B3 |
2.527e-04 | -8.28 | TUBGCP3 (tubulin gamma complex component 3) | protein interactions | 10426 | 221 | 5 | 19454 | 50 |
RPL8,RPL37A,RPS14,RPS25,NTRK1 |
2.529e-04 | -8.28 | RB1CC1 (RB1 inducible coiled-coil 1) | protein interactions | 9821 | 347 | 6 | 19454 | 50 |
RPL37A,RPL14,RPL27A,RPL8,RPS3A,RPL13A |
2.540e-04 | -8.28 | Ribosomal_zn-bd | interpro domains | IPR011332 | 9 | 2 | 18521 | 50 |
RPL36A,RPL37A |
2.596e-04 | -8.26 | IGF2BP3 (insulin like growth factor 2 mRNA binding protein 3) | protein interactions | 10643 | 496 | 7 | 19454 | 50 |
NTRK1,RPS20,RPL37A,RPL14,RPS3A,RBM47,RPL8 |
2.649e-04 | -8.24 | SHC1 (SHC adaptor protein 1) | protein interactions | 6464 | 350 | 6 | 19454 | 50 |
GAB1,CSF1R,NTRK1,SYK,ARAP1,PTPN6 |
2.650e-04 | -8.24 | ZRANB1 (zinc finger RANBP2-type containing 1) | protein interactions | 54764 | 4147 | 22 | 19454 | 50 |
RPS20,CADPS2,RAPGEF6,PSAP,RPS3A,RPL13A,RPL36A,RPL8,RPL18A,RPL12,RPL27A,RPS25,RPL14,RPL35,PTPN6,GNAI2,RPL37A,RPS14,RPL34,RPS26,ARAP1,IVNS1ABP |
2.693e-04 | -8.22 | CBL (Cbl proto-oncogene) | protein interactions | 867 | 499 | 7 | 19454 | 50 |
HCK,SYK,FYB1,GNAI2,PTPN6,NTRK1,CSF1R |
2.698e-04 | -8.22 | postsynaptic specialization | cellular component | GO:0099572 | 345 | 6 | 19108 | 50 |
RPS25,RPS14,RPL14,RPL12,DCC,RPL8 |
2.708e-04 | -8.21 | Mdm2 (transformed mouse 3T3 cell double minute 2) | protein interactions | 17246 | 49 | 3 | 19454 | 50 |
RPS25,RPS3A,RPS14 |
2.713e-04 | -8.21 | ZNF768 (zinc finger protein 768) | protein interactions | 79724 | 122 | 4 | 19454 | 50 |
RPL13A,RPL35,RPL14,RPL8 |
2.719e-04 | -8.21 | organic substance biosynthetic process | biological process | GO:1901576 | 4177 | 23 | 18204 | 50 |
RPL35,RPL27A,MAN1C1,RPL14,SYK,HIPK2,RPL36A,RBM47,RPL12,RPL18A,IVNS1ABP,RPL8,CD74,RXRA,CTSS,RPL37A,RPL13A,RPS3A,RPS14,RPS26,RPS25,RPS20,RPL34 |
2.783e-04 | -8.19 | phosphotyrosine residue binding | molecular function | GO:0001784 | 47 | 3 | 18094 | 49 |
HCK,SYK,PTPN6 |
2.802e-04 | -8.18 | PIK3R2 (phosphoinositide-3-kinase regulatory subunit 2) | protein interactions | 5296 | 226 | 5 | 19454 | 50 |
CSF1R,NTRK1,HCK,SYK,GAB1 |
2.860e-04 | -8.16 | EIF3G (eukaryotic translation initiation factor 3 subunit G) | protein interactions | 8666 | 227 | 5 | 19454 | 50 |
RPL14,NTRK1,RPS20,CD74,RPS26 |
2.887e-04 | -8.15 | SPATS2L (spermatogenesis associated serine rich 2 like) | protein interactions | 26010 | 124 | 4 | 19454 | 50 |
RPL13A,RPS20,RPL8,RPL14 |
2.893e-04 | -8.15 | CDK9 (cyclin dependent kinase 9) | protein interactions | 1025 | 672 | 8 | 19454 | 50 |
PTPN6,RPS26,RPS3A,RPL18A,HCK,RPS20,RPS25,RPL27A |
2.981e-04 | -8.12 | HNRNPM (heterogeneous nuclear ribonucleoprotein M) | protein interactions | 4670 | 675 | 8 | 19454 | 50 |
RPS26,RPL18A,RPL12,IVNS1ABP,RPS25,NTRK1,RPL14,RPS14 |
3.068e-04 | -8.09 | NMNAT1 (nicotinamide nucleotide adenylyltransferase 1) | protein interactions | 64802 | 126 | 4 | 19454 | 50 |
RPL35,RPL8,RPS3A,PTPN6 |
3.126e-04 | -8.07 | CRK (CRK proto-oncogene, adaptor protein) | protein interactions | 1398 | 361 | 6 | 19454 | 50 |
NTRK1,RPS25,ARAP1,IVNS1ABP,GAB1,ELMO1 |
3.129e-04 | -8.07 | Gene Expression | REACTOME pathways | R-HSA-74160 | 1821 | 17 | 10285 | 41 |
RXRA,RPL13A,RPS26,RPL12,RPS20,RPL8,RPL18A,RPL37A,RPL36A,RPS14,HIPK2,RPL14,RPL27A,RPS3A,RPS25,RPL35,RPL34 |
3.132e-04 | -8.07 | RA | prosite domains | PS50200 | 37 | 3 | 12186 | 44 |
ARAP1,RAPGEF6,RGL1 |
3.162e-04 | -8.06 | URB1 (URB1 ribosome biogenesis homolog) | protein interactions | 9875 | 127 | 4 | 19454 | 50 |
RPL13A,RPL18A,RPL14,RPS14 |
3.167e-04 | -8.06 | positive regulation of molecular function | biological process | GO:0044093 | 1192 | 11 | 18204 | 50 |
CSF1R,ARAP1,NTRK1,CARD10,RXRA,CD74,SYK,CTSS,HIPK2,RAPGEF6,PSAP |
3.231e-04 | -8.04 | SH2B2 (SH2B adaptor protein 2) | protein interactions | 10603 | 52 | 3 | 19454 | 50 |
NTRK1,HCK,SYK |
3.258e-04 | -8.03 | GAB2 (GRB2 associated binding protein 2) | protein interactions | 9846 | 128 | 4 | 19454 | 50 |
GAB1,SYK,PTPN6,NTRK1 |
3.320e-04 | -8.01 | biosynthetic process | biological process | GO:0009058 | 4231 | 23 | 18204 | 50 |
CD74,RXRA,CTSS,SYK,RPL13A,RPL37A,RPL35,IVNS1ABP,RPL27A,RPL14,RPL8,MAN1C1,RPL12,RPL18A,HIPK2,RPS14,RPL36A,RPS3A,RPS26,RBM47,RPS20,RPS25,RPL34 |
3.495e-04 | -7.96 | DDX39B (DExD-box helicase 39B) | protein interactions | 7919 | 521 | 7 | 19454 | 50 |
GNAI2,HIPK2,RPL12,RPS3A,SPECC1,NTRK1,RPS25 |
3.513e-04 | -7.95 | PDCD11 (programmed cell death 11) | protein interactions | 22984 | 369 | 6 | 19454 | 50 |
NTRK1,RPL13A,RPS14,RPL8,RPL18A,SYK |
3.555e-04 | -7.94 | YTHDF3 (YTH N6-methyladenosine RNA binding protein F3) | protein interactions | 253943 | 238 | 5 | 19454 | 50 |
CTSS,RPS20,RBM47,CSF1R,NTRK1 |
3.559e-04 | -7.94 | PROTEIN_KINASE_TYR | prosite domains | PS00109 | 94 | 4 | 12186 | 44 |
CSF1R,HCK,NTRK1,SYK |
3.613e-04 | -7.93 | Brwd3 (bromodomain and WD repeat domain containing 3) | protein interactions | 382236 | 54 | 3 | 19454 | 50 |
RPL18A,RPL35,RPL37A |
3.646e-04 | -7.92 | neuron to neuron synapse | cellular component | GO:0098984 | 365 | 6 | 19108 | 50 |
RPS14,RPS25,RPL12,RPL14,RPL8,DCC |
3.662e-04 | -7.91 | ZCRB1 (zinc finger CCHC-type and RNA binding motif containing 1) | protein interactions | 85437 | 132 | 4 | 19454 | 50 |
RPS3A,RBM47,RPL13A,RPL35 |
3.662e-04 | -7.91 | TXNDC12 (thioredoxin domain containing 12) | protein interactions | 51060 | 132 | 4 | 19454 | 50 |
PSAP,CTSS,DIAPH2,HCK |
3.668e-04 | -7.91 | ZNF346 (zinc finger protein 346) | protein interactions | 23567 | 372 | 6 | 19454 | 50 |
RPS3A,RPL27A,RPL14,RPL37A,RPS14,RPL35 |
3.668e-04 | -7.91 | GRM2 (glutamate metabotropic receptor 2) | protein interactions | 2912 | 372 | 6 | 19454 | 50 |
RPS3A,RPL13A,RPL14,RPS14,RPL12,RPL18A |
3.694e-04 | -7.90 | MRPL28 (mitochondrial ribosomal protein L28) | protein interactions | 10573 | 240 | 5 | 19454 | 50 |
RPL13A,RPS3A,NTRK1,RPL27A,RPL35 |
3.694e-04 | -7.90 | HERC5 (HECT and RLD domain containing E3 ubiquitin protein ligase 5) | protein interactions | 51191 | 240 | 5 | 19454 | 50 |
RPL14,RBM47,RPL13A,NTRK1,RPS3A |
3.697e-04 | -7.90 | CSNK2A2 (casein kinase 2 alpha 2) | protein interactions | 1459 | 697 | 8 | 19454 | 50 |
RPS20,RPS25,NTRK1,RPL27A,RPL34,RPS3A,RPL12,RPL8 |
3.815e-04 | -7.87 | DOCK1 (dedicator of cytokinesis 1) | protein interactions | 1793 | 55 | 3 | 19454 | 50 |
NTRK1,DIAPH2,ELMO1 |
3.837e-04 | -7.87 | ZNF574 (zinc finger protein 574) | protein interactions | 64763 | 242 | 5 | 19454 | 50 |
NTRK1,RPL13A,RPL14,RPL35,RPS14 |
3.847e-04 | -7.86 | SH2 | smart domains | SM00252 | 103 | 4 | 9717 | 33 |
HCK,SH2B3,PTPN6,SYK |
3.984e-04 | -7.83 | CBX8 (chromobox 8) | protein interactions | 57332 | 244 | 5 | 19454 | 50 |
RPS14,CARD10,RPL18A,RPS3A,RPS20 |
3.988e-04 | -7.83 | Myo1c (myosin IC) | protein interactions | 17913 | 135 | 4 | 19454 | 50 |
BMP2K,FCHO2,CARD10,SPECC1 |
4.008e-04 | -7.82 | SMURF1 (SMAD specific E3 ubiquitin protein ligase 1) | protein interactions | 57154 | 533 | 7 | 19454 | 50 |
RPS14,RPL35,RPS20,RPS25,IVNS1ABP,RPL13A,RPS3A |
4.101e-04 | -7.80 | TLE2 (TLE family member 2, transcriptional corepressor) | protein interactions | 7089 | 136 | 4 | 19454 | 50 |
RPS14,RPL27A,RPS25,RPL13A |
4.101e-04 | -7.80 | LLPH (LLP homolog, long-term synaptic facilitation factor) | protein interactions | 84298 | 136 | 4 | 19454 | 50 |
RPS3A,RPL12,RPL14,RPL37A |
4.104e-04 | -7.80 | SRPK2 (SRSF protein kinase 2) | protein interactions | 6733 | 708 | 8 | 19454 | 50 |
RPL14,CADPS2,RPL34,NTRK1,RPL18A,RPS3A,RPL13A,RPS26 |
4.203e-04 | -7.77 | SOWAHB (sosondowah ankyrin repeat domain family member B) | protein interactions | 345079 | 12 | 2 | 19454 | 50 |
DIAPH2,RAPGEF6 |
4.276e-04 | -7.76 | Nef and signal transduction | REACTOME pathways | R-HSA-164944 | 8 | 2 | 10285 | 41 |
HCK,ELMO1 |
4.291e-04 | -7.75 | MET (MET proto-oncogene, receptor tyrosine kinase) | protein interactions | 4233 | 248 | 5 | 19454 | 50 |
SH2B3,ITM2B,HCK,SYK,GAB1 |
4.291e-04 | -7.75 | ABL1 (ABL proto-oncogene 1, non-receptor tyrosine kinase) | protein interactions | 25 | 248 | 5 | 19454 | 50 |
PTPN6,NTRK1,HCK,HIPK2,BMP2K |
4.372e-04 | -7.74 | regulation of MAPK cascade | biological process | GO:0043408 | 669 | 8 | 18204 | 50 |
HIPK2,CSF1R,SH2B3,NTRK1,CD74,PTPN6,SYK,GNAI2 |
4.462e-04 | -7.71 | PPCS (phosphopantothenoylcysteine synthetase) | protein interactions | 79717 | 58 | 3 | 19454 | 50 |
RPL36A,PDZRN3,RPL35 |
4.532e-04 | -7.70 | Ser-Thr/Tyr_kinase_cat_dom | interpro domains | IPR001245 | 133 | 4 | 18521 | 50 |
HCK,SYK,NTRK1,CSF1R |
4.537e-04 | -7.70 | SH2 domain | gene3d domains | 3.30.505.10 | 111 | 4 | 14470 | 47 |
PTPN6,SYK,SH2B3,HCK |
4.547e-04 | -7.70 | CAV1 (caveolin 1) | protein interactions | 857 | 719 | 8 | 19454 | 50 |
PTPN6,ITM2B,IVNS1ABP,GNAI2,NTRK1,GAB1,SPECC1,RAPGEF6 |
4.616e-04 | -7.68 | EIF3C (eukaryotic translation initiation factor 3 subunit C) | protein interactions | 8663 | 252 | 5 | 19454 | 50 |
RPL8,CD74,RPS20,RPS3A,NTRK1 |
4.712e-04 | -7.66 | DCPS (decapping enzyme, scavenger) | protein interactions | 28960 | 390 | 6 | 19454 | 50 |
RPL12,RPS14,GNAI2,RPS20,RPS25,NTRK1 |
4.828e-04 | -7.64 | PK_Tyr_Ser-Thr | pfam domains | PF07714 | 130 | 4 | 17795 | 50 |
SYK,NTRK1,CSF1R,HCK |
4.829e-04 | -7.64 | Myh10 (myosin, heavy polypeptide 10, non-muscle) | protein interactions | 77579 | 142 | 4 | 19454 | 50 |
CARD10,SPECC1,BMP2K,GNAI2 |
4.958e-04 | -7.61 | MRPS18A (mitochondrial ribosomal protein S18A) | protein interactions | 55168 | 143 | 4 | 19454 | 50 |
RPL35,RPL27A,RBM47,RPL13A |
4.959e-04 | -7.61 | FCRL3 (Fc receptor like 3) | protein interactions | 115352 | 13 | 2 | 19454 | 50 |
PTPN6,SYK |
5.047e-04 | -7.59 | NSD2 (nuclear receptor binding SET domain protein 2) | protein interactions | 7468 | 257 | 5 | 19454 | 50 |
RPL14,RPL37A,RPL8,RPS26,RPS3A |
5.228e-04 | -7.56 | PURA (purine rich element binding protein A) | protein interactions | 5813 | 259 | 5 | 19454 | 50 |
RPL35,RPL14,SYK,NTRK1,RPL13A |
5.257e-04 | -7.55 | positive regulation of catalytic activity | biological process | GO:0043085 | 868 | 9 | 18204 | 50 |
NTRK1,CARD10,ARAP1,CSF1R,RAPGEF6,CTSS,SYK,PSAP,CD74 |
5.272e-04 | -7.55 | VHL (von Hippel-Lindau tumor suppressor) | protein interactions | 7428 | 558 | 7 | 19454 | 50 |
DIAPH2,RPS3A,RPL12,RPL18A,RPS14,RPL14,IVNS1ABP |
5.321e-04 | -7.54 | PA2G4 (proliferation-associated 2G4) | protein interactions | 5036 | 260 | 5 | 19454 | 50 |
RPL18A,RPL12,RPL8,PTPN6,NTRK1 |
5.382e-04 | -7.53 | human chr7q31.32 | chromosome location | human chr7q31.32 | 18 | 2 | 26134 | 50 |
CADPS2,SLC13A1 |
5.533e-04 | -7.50 | CSNK2A1 (casein kinase 2 alpha 1) | protein interactions | 1457 | 934 | 9 | 19454 | 50 |
RPL8,RPL13A,RPL36A,RPS3A,RPS14,RPS25,RPS20,RPL27A,NTRK1 |
5.563e-04 | -7.49 | membrane | cellular component | GO:0016020 | 9220 | 36 | 19108 | 50 |
MAN1C1,RPS14,ARAP1,CADPS2,RPS20,RPS26,RPL35,RPL36A,SH2B3,RPL12,SLC13A1,RAPGEF6,GNAI2,FCHO2,SYK,RGL1,HCK,RPL8,NTRK1,RPL13A,ENTPD1,CSF1R,ADAM28,ITGAX,RPL14,ELMO1,CD74,RPL18A,DCC,FYB1,PSAP,SPECC1,RPL27A,PDE6D,ITM2B,PTPN6 |
5.730e-04 | -7.46 | protein phosphorylated amino acid binding | molecular function | GO:0045309 | 60 | 3 | 18094 | 49 |
SYK,PTPN6,HCK |
5.737e-04 | -7.46 | ILF2 (interleukin enhancer binding factor 2) | protein interactions | 3608 | 566 | 7 | 19454 | 50 |
RPL14,RPS20,NTRK1,RPL8,IVNS1ABP,RPS26,RPS3A |
5.776e-04 | -7.46 | MS4A2 (membrane spanning 4-domains A2) | protein interactions | 2206 | 14 | 2 | 19454 | 50 |
SYK,PTPN6 |
5.776e-04 | -7.46 | Tuba1a (tubulin, alpha 1A) | protein interactions | 22142 | 14 | 2 | 19454 | 50 |
GNAI2,RPL12 |
5.821e-04 | -7.45 | SH2 | prosite domains | PS50001 | 107 | 4 | 12186 | 44 |
HCK,SYK,SH2B3,PTPN6 |
6.148e-04 | -7.39 | cytokine-mediated signaling pathway | biological process | GO:0019221 | 384 | 6 | 18204 | 50 |
HCK,SH2B3,CSF1R,CD74,SYK,PTPN6 |
6.207e-04 | -7.38 | AHSA1 (activator of HSP90 ATPase activity 1) | protein interactions | 10598 | 269 | 5 | 19454 | 50 |
RPS14,RPS25,RPS20,RPS3A,NTRK1 |
6.289e-04 | -7.37 | H1-5 (H1.5 linker histone, cluster member) | protein interactions | 3009 | 412 | 6 | 19454 | 50 |
NTRK1,RPS25,RPS20,RPL37A,RPS14,RPS3A |
6.366e-04 | -7.36 | Translation_prot_SH3-like_sf | interpro domains | IPR008991 | 14 | 2 | 18521 | 50 |
RPL8,RPL14 |
6.523e-04 | -7.34 | PDE4B (phosphodiesterase 4B) | protein interactions | 5142 | 66 | 3 | 19454 | 50 |
NTRK1,RPS20,RPL35 |
6.523e-04 | -7.34 | MICB (MHC class I polypeptide-related sequence B) | protein interactions | 4277 | 66 | 3 | 19454 | 50 |
RPL36A,BMP2K,RPL37A |
6.523e-04 | -7.34 | ZFP62 (ZFP62 zinc finger protein) | protein interactions | 643836 | 66 | 3 | 19454 | 50 |
RPL13A,RPL37A,RPL14 |
6.553e-04 | -7.33 | H2AC11 (H2A clustered histone 11) | protein interactions | 8969 | 154 | 4 | 19454 | 50 |
RPL37A,RPL35,RPL13A,RPS3A |
6.553e-04 | -7.33 | RAP1A (RAP1A, member of RAS oncogene family) | protein interactions | 5906 | 154 | 4 | 19454 | 50 |
RAPGEF6,RGL1,PDE6D,NTRK1 |
6.553e-04 | -7.33 | RPL37 (ribosomal protein L37) | protein interactions | 6167 | 154 | 4 | 19454 | 50 |
PTPN6,RPL37A,RPL12,HCK |
6.630e-04 | -7.32 | SERBP1 (SERPINE1 mRNA binding protein 1) | protein interactions | 26135 | 580 | 7 | 19454 | 50 |
RPL37A,RPS14,RPS20,RPS25,NTRK1,RPS26,RPS3A |
6.742e-04 | -7.30 | STIP1 (stress induced phosphoprotein 1) | protein interactions | 10963 | 960 | 9 | 19454 | 50 |
RPS3A,RPL8,RPL18A,RPL12,RPL27A,NTRK1,RPS25,RPL14,RPL34 |
6.835e-04 | -7.29 | ERBB2 (erb-b2 receptor tyrosine kinase 2) | protein interactions | 2064 | 583 | 7 | 19454 | 50 |
PSAP,NTRK1,SH2B3,PTPN6,HCK,GAB1,SYK |
6.962e-04 | -7.27 | HSP90AB1 (heat shock protein 90 alpha family class B member 1) | protein interactions | 3326 | 767 | 8 | 19454 | 50 |
NTRK1,RPL14,RPS26,RPS3A,PSAP,HCK,IVNS1ABP,GNAI2 |
7.082e-04 | -7.25 | GRB2 (growth factor receptor bound protein 2) | protein interactions | 2885 | 769 | 8 | 19454 | 50 |
ARAP1,PTPN6,SYK,SH2B3,RPS20,CSF1R,NTRK1,GAB1 |
7.201e-04 | -7.24 | NOP58 (NOP58 ribonucleoprotein) | protein interactions | 51602 | 278 | 5 | 19454 | 50 |
RPS3A,NTRK1,RPL37A,RPS14,RPL18A |
7.260e-04 | -7.23 | FBXO7 (F-box protein 7) | protein interactions | 25793 | 589 | 7 | 19454 | 50 |
RPL14,RPL37A,RPS20,RPS25,RPL36A,RPS26,RPS3A |
7.318e-04 | -7.22 | TPT1 (tumor protein, translationally-controlled 1) | protein interactions | 7178 | 279 | 5 | 19454 | 50 |
RPL14,RPS20,RPS25,RPS26,RPL27A |
7.333e-04 | -7.22 | DHX9 (DExH-box helicase 9) | protein interactions | 1660 | 590 | 7 | 19454 | 50 |
NTRK1,RPL27A,RPS14,RPL37A,RPS3A,RPS26,IVNS1ABP |
7.356e-04 | -7.21 | PH_domain | interpro domains | IPR001849 | 266 | 5 | 18521 | 50 |
CADPS2,GAB1,SH2B3,ELMO1,ARAP1 |
7.428e-04 | -7.21 | PPP4R3B (protein phosphatase 4 regulatory subunit 3B) | protein interactions | 57223 | 69 | 3 | 19454 | 50 |
SYK,NTRK1,RPS3A |
7.592e-04 | -7.18 | SELPLG (selectin P ligand) | protein interactions | 6404 | 16 | 2 | 19454 | 50 |
SLC13A1,SYK |
7.592e-04 | -7.18 | EML5 (EMAP like 5) | protein interactions | 161436 | 16 | 2 | 19454 | 50 |
NTRK1,RPL27A |
7.672e-04 | -7.17 | HADHB (hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit beta) | protein interactions | 3032 | 428 | 6 | 19454 | 50 |
CD74,RPS3A,NTRK1,SYK,RPL35,GNAI2 |
7.679e-04 | -7.17 | EPO signaling pathway | Pathway Interaction DB | epopathway | 33 | 3 | 2226 | 13 |
SH2B3,PTPN6,GAB1 |
7.802e-04 | -7.16 | SND1 (staphylococcal nuclease and tudor domain containing 1) | protein interactions | 27044 | 283 | 5 | 19454 | 50 |
RPL35,RPS26,RPS20,NTRK1,RPS3A |
7.866e-04 | -7.15 | T cell receptor complex | cellular component | GO:0042101 | 16 | 2 | 19108 | 50 |
PTPN6,SYK |
7.927e-04 | -7.14 | Dppa3 (developmental pluripotency-associated 3) | protein interactions | 73708 | 284 | 5 | 19454 | 50 |
RPL18A,RPL14,RPL13A,RPS26,RPL27A |
8.053e-04 | -7.12 | DHX8 (DEAH-box helicase 8) | protein interactions | 1659 | 285 | 5 | 19454 | 50 |
RPL8,RPL14,RPL18A,NTRK1,RPL13A |
8.053e-04 | -7.12 | SART3 (spliceosome associated factor 3, U4/U6 recycling protein) | protein interactions | 9733 | 285 | 5 | 19454 | 50 |
RPS3A,NTRK1,RPL13A,RPL37A,SYK |
8.174e-04 | -7.11 | HSF1 (heat shock transcription factor 1) | protein interactions | 3297 | 601 | 7 | 19454 | 50 |
RPS3A,RPL8,PDZRN3,IVNS1ABP,RPL12,RPL35,RPL37A |
8.602e-04 | -7.06 | positive regulation of signaling | biological process | GO:0023056 | 1794 | 13 | 18204 | 50 |
GNAI2,PTPN6,RPS20,RBM47,HIPK2,SYK,CTSS,RXRA,CD74,NTRK1,ARAP1,CSF1R,BMP2K |
8.673e-04 | -7.05 | PSMD9 (proteasome 26S subunit, non-ATPase 9) | protein interactions | 5715 | 166 | 4 | 19454 | 50 |
RPS14,RPS3A,RPS25,RPS20 |
8.870e-04 | -7.03 | ZCCHC3 (zinc finger CCHC-type containing 3) | protein interactions | 85364 | 167 | 4 | 19454 | 50 |
RPL35,RPS20,RBM47,RPS3A |
8.886e-04 | -7.03 | regulation of programmed cell death | biological process | GO:0043067 | 1569 | 12 | 18204 | 50 |
HIPK2,RPS3A,GNAI2,PTPN6,HCK,CARD10,NTRK1,IVNS1ABP,CSF1R,SYK,CTSS,CD74 |
8.938e-04 | -7.02 | LRRC59 (leucine rich repeat containing 59) | protein interactions | 55379 | 797 | 8 | 19454 | 50 |
RPL35,RPL37A,RPL14,NTRK1,RPL18A,RPL12,RPL8,RPS3A |
8.966e-04 | -7.02 | lymph_node | COSMIC cancer mutations | lymph_node | 1703 | 13 | 16828 | 49 |
IVNS1ABP,HCK,HIPK2,NTRK1,GNAI2,SYK,CSF1R,CD74,RPL12,DCC,ELMO1,PDZRN3,SLC13A1 |
9.069e-04 | -7.01 | GAB1 (GRB2 associated binding protein 1) | protein interactions | 2549 | 168 | 4 | 19454 | 50 |
NTRK1,SYK,GAB1,HCK |
9.104e-04 | -7.00 | intracellular non-membrane-bounded organelle | cellular component | GO:0043232 | 5729 | 26 | 19108 | 50 |
RPL8,RAPGEF6,RPL12,GNAI2,RPL37A,HCK,RPS3A,DIAPH2,RPS20,RPS26,IVNS1ABP,RPL35,RPL36A,RPS14,RPL34,PTPN6,FYB1,SPECC1,RPL27A,PDE6D,HIPK2,RPL14,RPL18A,RXRA,RPL13A,RPS25 |
9.108e-04 | -7.00 | Ktn1 (kinectin 1) | protein interactions | 16709 | 74 | 3 | 19454 | 50 |
RPL18A,RPL27A,RPL13A |
9.157e-04 | -7.00 | non-membrane-bounded organelle | cellular component | GO:0043228 | 5731 | 26 | 19108 | 50 |
RPL8,RAPGEF6,RPL12,GNAI2,RPL37A,HCK,RPS3A,RPS20,DIAPH2,RPS26,RPL35,IVNS1ABP,RPL36A,RPS14,RPL34,PTPN6,FYB1,SPECC1,RPL27A,PDE6D,HIPK2,RPL14,RPL18A,RXRA,RPL13A,RPS25 |
9.397e-04 | -6.97 | RRP12 (ribosomal RNA processing 12 homolog) | protein interactions | 23223 | 295 | 5 | 19454 | 50 |
NTRK1,RPS3A,SYK,RPS14,RPL35 |
9.685e-04 | -6.94 | TRIM5 (tripartite motif containing 5) | protein interactions | 574288 | 297 | 5 | 19454 | 50 |
RPS26,RPL13A,RPL18A,RPL12,RPL8 |
1.016e-03 | -6.89 | positive regulation of signal transduction | biological process | GO:0009967 | 1593 | 12 | 18204 | 50 |
RBM47,CSF1R,BMP2K,HIPK2,NTRK1,RPS20,RXRA,CD74,GNAI2,SYK,CTSS,PTPN6 |
1.018e-03 | -6.89 | positive regulation of chemokine production | biological process | GO:0032722 | 72 | 3 | 18204 | 50 |
CSF1R,CD74,SYK |
1.022e-03 | -6.89 | intracellular anatomical structure | cellular component | GO:0005622 | 15205 | 48 | 19108 | 50 |
RGL1,SYK,RAPGEF6,SH2B3,FCHO2,GNAI2,RPL34,CTSS,MAN1C1,RPS26,RPL36A,RPS20,PDE6D,RBM47,PSAP,FYB1,BMP2K,GAB1,ITM2B,CSF1R,CARD10,RPL18A,ITGAX,HIPK2,RPL37A,HCK,RPL12,RPL8,PDZRN3,ARAP1,RPS14,RPL35,IVNS1ABP,RPS3A,CADPS2,DIAPH2,SPECC1,RPL27A,PTPN6,ADAM28,RPL13A,RPS25,NTRK1,CD74,RXRA,DCC,RPL14,ELMO1 |
1.077e-03 | -6.83 | TET3 (tet methylcytosine dioxygenase 3) | protein interactions | 200424 | 19 | 2 | 19454 | 50 |
RPL14,RPL13A |
1.080e-03 | -6.83 | angioimmunoblastic_T_cell_lymphoma | COSMIC cancer mutations | angioimmunoblastic_T_cell_lymphoma | 269 | 5 | 16828 | 49 |
CTSS,SYK,SH2B3,CSF1R,HCK |
1.080e-03 | -6.83 | cell surface receptor protein tyrosine kinase signaling pathway | biological process | GO:0007169 | 428 | 6 | 18204 | 50 |
SYK,GAB1,HCK,NTRK1,CSF1R,SH2B3 |
1.100e-03 | -6.81 | positive regulation of superoxide anion generation | biological process | GO:0032930 | 18 | 2 | 18204 | 50 |
GNAI2,SYK |
1.101e-03 | -6.81 | MRPL16 (mitochondrial ribosomal protein L16) | protein interactions | 54948 | 177 | 4 | 19454 | 50 |
RPL13A,RBM47,RPL27A,RPL35 |
1.101e-03 | -6.81 | KMT5A (lysine methyltransferase 5A) | protein interactions | 387893 | 79 | 3 | 19454 | 50 |
RPL8,RPL37A,RPL35 |
1.101e-03 | -6.81 | PRDM15 (PR/SET domain 15) | protein interactions | 63977 | 79 | 3 | 19454 | 50 |
RPL13A,RPL37A,RPL8 |
1.106e-03 | -6.81 | primary metabolic process | biological process | GO:0044238 | 7206 | 31 | 18204 | 50 |
CTSS,RPL37A,RPL13A,CD74,RXRA,RPL8,ADAM28,CSF1R,IVNS1ABP,PDZRN3,PTPN6,ENTPD1,RPS25,RPS20,RPL34,RPS3A,RPS14,RPS26,SYK,RPL27A,MAN1C1,NTRK1,RPL14,RPL35,RPL18A,PSAP,HCK,RPL12,HIPK2,RPL36A,RBM47 |
1.117e-03 | -6.80 | ORF6 (ORF6 protein) | protein interactions | 43740572 | 825 | 8 | 19454 | 50 |
RPS3A,RPS26,RPL8,IVNS1ABP,RPL12,RPS25,RPL14,RPL35 |
1.124e-03 | -6.79 | ERBB4 (erb-b2 receptor tyrosine kinase 4) | protein interactions | 2066 | 178 | 4 | 19454 | 50 |
SH2B3,PTPN6,HCK,SYK |
1.176e-03 | -6.75 | FCGR activation | REACTOME pathways | R-HSA-2029481 | 13 | 2 | 10285 | 41 |
SYK,HCK |
1.176e-03 | -6.75 | Signal regulatory protein (SIRP) family interactions | REACTOME pathways | R-HSA-391160 | 13 | 2 | 10285 | 41 |
PTPN6,FYB1 |
1.179e-03 | -6.74 | RHOB (ras homolog family member B) | protein interactions | 388 | 832 | 8 | 19454 | 50 |
GAB1,SPECC1,RAPGEF6,PDE6D,FCHO2,GNAI2,RPL13A,DIAPH2 |
1.195e-03 | -6.73 | PRKD1 (protein kinase D1) | protein interactions | 5587 | 181 | 4 | 19454 | 50 |
IVNS1ABP,RPL14,GNAI2,SYK |
1.245e-03 | -6.69 | HCK (HCK proto-oncogene, Src family tyrosine kinase) | protein interactions | 3055 | 183 | 4 | 19454 | 50 |
IVNS1ABP,HCK,GAB1,ELMO1 |
1.255e-03 | -6.68 | env (Envelope surface glycoprotein gp160, precursor) | protein interactions | 155971 | 1501 | 11 | 19454 | 50 |
CTSS,RPL8,RXRA,MAN1C1,RPL14,ITGAX,NTRK1,GNAI2,HCK,ITM2B,CD74 |
1.261e-03 | -6.68 | myeloid cell differentiation | biological process | GO:0030099 | 295 | 5 | 18204 | 50 |
PTPN6,SH2B3,CSF1R,HIPK2,RPS14 |
1.276e-03 | -6.66 | MRPS5 (mitochondrial ribosomal protein S5) | protein interactions | 64969 | 316 | 5 | 19454 | 50 |
RPL13A,RBM47,NTRK1,SYK,RPL35 |
1.312e-03 | -6.64 | CCDC8 (coiled-coil domain containing 8) | protein interactions | 83987 | 652 | 7 | 19454 | 50 |
GNAI2,RPL8,RPS3A,RPL13A,RPL14,RPS14,SPECC1 |
1.314e-03 | -6.63 | TP53 (tumor protein p53) | protein interactions | 7157 | 2268 | 14 | 19454 | 50 |
RPS26,RPS3A,HIPK2,SYK,RPL12,RPL18A,RPL8,RPS25,CTSS,RPL27A,ADAM28,RPS14,RPL37A,RPL14 |
1.314e-03 | -6.63 | haematopoietic_and_lymphoid_tissue-lymph_node-lymphoid_neoplasm-diffuse_large_B_cell_lymphoma | COSMIC cancer mutations | haematopoietic_and_lymphoid_tissue-lymph_node-lymphoid_neoplasm-diffuse_large_B_cell_lymphoma | 748 | 8 | 16828 | 49 |
GNAI2,IVNS1ABP,CD74,HCK,DCC,RPL12,ELMO1,NTRK1 |
1.316e-03 | -6.63 | Rib_uL2_dom2 | interpro domains | IPR014722 | 20 | 2 | 18521 | 50 |
RPL8,RPL14 |
1.318e-03 | -6.63 | SGSM3 (small G protein signaling modulator 3) | protein interactions | 27352 | 21 | 2 | 19454 | 50 |
RPL35,NTRK1 |
1.318e-03 | -6.63 | ZNF431 (zinc finger protein 431) | protein interactions | 170959 | 21 | 2 | 19454 | 50 |
RPL27A,RPL13A |
1.322e-03 | -6.63 | Actb (actin, beta) | protein interactions | 11461 | 186 | 4 | 19454 | 50 |
GNAI2,BMP2K,SPECC1,FCHO2 |
1.332e-03 | -6.62 | PRKN (parkin RBR E3 ubiquitin protein ligase) | protein interactions | 5071 | 3398 | 18 | 19454 | 50 |
RPS3A,RPL13A,RPL36A,RPL8,RPL18A,RPL12,RPS20,RPL37A,RPS26,DIAPH2,ARAP1,GNAI2,RPL27A,RPS25,RPL35,RPS14,RPL14,RPL34 |
1.349e-03 | -6.61 | SRRM1 (serine and arginine repetitive matrix 1) | protein interactions | 10250 | 320 | 5 | 19454 | 50 |
PTPN6,RPL13A,NTRK1,RPL18A,RPL14 |
1.356e-03 | -6.60 | USP15 (ubiquitin specific peptidase 15) | protein interactions | 9958 | 478 | 6 | 19454 | 50 |
NTRK1,RPL37A,RPL13A,RPS3A,RPL18A,IVNS1ABP |
1.360e-03 | -6.60 | NENF (neudesin neurotrophic factor) | protein interactions | 29937 | 85 | 3 | 19454 | 50 |
RPS3A,RPS26,RPL14 |
1.361e-03 | -6.60 | immune response-regulating cell surface receptor signaling pathway involved in phagocytosis | biological process | GO:0002433 | 20 | 2 | 18204 | 50 |
SYK,HCK |
1.361e-03 | -6.60 | Fc-gamma receptor signaling pathway involved in phagocytosis | biological process | GO:0038096 | 20 | 2 | 18204 | 50 |
SYK,HCK |
1.375e-03 | -6.59 | MST1R (macrophage stimulating 1 receptor) | protein interactions | 4486 | 188 | 4 | 19454 | 50 |
RPL34,GAB1,RPL35,RPL27A |
1.398e-03 | -6.57 | immune response-activating signaling pathway | biological process | GO:0002757 | 302 | 5 | 18204 | 50 |
SYK,PTPN6,FYB1,CTSS,HCK |
1.407e-03 | -6.57 | MDK (midkine) | protein interactions | 4192 | 86 | 3 | 19454 | 50 |
RPL35,RPL18A,HCK |
1.423e-03 | -6.55 | RasGEF_N | pfam domains | PF00618 | 20 | 2 | 17795 | 50 |
RGL1,RAPGEF6 |
1.447e-03 | -6.54 | FCGR2B (Fc gamma receptor IIb) | protein interactions | 2213 | 22 | 2 | 19454 | 50 |
PTPN6,GAB1 |
1.472e-03 | -6.52 | cytoplasmic vesicle | cellular component | GO:0031410 | 2521 | 15 | 19108 | 50 |
CD74,DIAPH2,CADPS2,ITGAX,CTSS,NTRK1,PTPN6,ITM2B,HCK,SYK,PDE6D,GNAI2,FCHO2,PSAP,RAPGEF6 |
1.482e-03 | -6.51 | ribosome biogenesis | biological process | GO:0042254 | 306 | 5 | 18204 | 50 |
RPL35,RPS3A,RPS14,RPL14,RPS25 |
1.484e-03 | -6.51 | kidney-carcinoma-chromophobe_renal_cell_carcinoma | COSMIC cancer mutations | kidney-carcinoma-chromophobe_renal_cell_carcinoma | 430 | 6 | 16828 | 49 |
NTRK1,CSF1R,HCK,SYK,HIPK2,BMP2K |
1.484e-03 | -6.51 | chromophobe_renal_cell_carcinoma | COSMIC cancer mutations | chromophobe_renal_cell_carcinoma | 430 | 6 | 16828 | 49 |
NTRK1,HIPK2,HCK,CSF1R,SYK,BMP2K |
1.491e-03 | -6.51 | lobular_carcinoma | COSMIC cancer mutations | lobular_carcinoma | 763 | 8 | 16828 | 49 |
HIPK2,NTRK1,SYK,RBM47,BMP2K,SPECC1,HCK,CSF1R |
1.491e-03 | -6.51 | breast-carcinoma-lobular_carcinoma | COSMIC cancer mutations | breast-carcinoma-lobular_carcinoma | 763 | 8 | 16828 | 49 |
HCK,SPECC1,CSF1R,SYK,BMP2K,RBM47,NTRK1,HIPK2 |
1.496e-03 | -6.51 | PINK1 (PTEN induced kinase 1) | protein interactions | 65018 | 667 | 7 | 19454 | 50 |
RPL27A,RPS3A,SPECC1,RPL12,RPS14,RPL14,RPL35 |
1.502e-03 | -6.50 | regulation of superoxide anion generation | biological process | GO:0032928 | 21 | 2 | 18204 | 50 |
SYK,GNAI2 |
1.509e-03 | -6.50 | intracellular vesicle | cellular component | GO:0097708 | 2527 | 15 | 19108 | 50 |
RAPGEF6,PSAP,FCHO2,GNAI2,PDE6D,SYK,HCK,ITM2B,PTPN6,NTRK1,CTSS,ITGAX,CADPS2,DIAPH2,CD74 |
1.519e-03 | -6.49 | enzyme-linked receptor protein signaling pathway | biological process | GO:0007167 | 626 | 7 | 18204 | 50 |
NTRK1,SH2B3,HIPK2,CSF1R,SYK,GAB1,HCK |
1.543e-03 | -6.47 | CNPY3 (canopy FGF signaling regulator 3) | protein interactions | 10695 | 194 | 4 | 19454 | 50 |
HCK,CD74,CTSS,DIAPH2 |
1.553e-03 | -6.47 | SLC25A41 (solute carrier family 25 member 41) | protein interactions | 284427 | 89 | 3 | 19454 | 50 |
FCHO2,SPECC1,BMP2K |
1.572e-03 | -6.46 | MRPL1 (mitochondrial ribosomal protein L1) | protein interactions | 65008 | 195 | 4 | 19454 | 50 |
RPL12,RPS20,RPL13A,RPL27A |
1.572e-03 | -6.46 | CRBN (cereblon) | protein interactions | 51185 | 195 | 4 | 19454 | 50 |
IVNS1ABP,RPL35,RPS3A,RPS25 |
1.582e-03 | -6.45 | Poc1b (POC1 centriolar protein B) | protein interactions | 382406 | 23 | 2 | 19454 | 50 |
SPECC1,GNAI2 |
1.594e-03 | -6.44 | Ras-like_Gua-exchang_fac_N | interpro domains | IPR000651 | 22 | 2 | 18521 | 50 |
RGL1,RAPGEF6 |
1.610e-03 | -6.43 | human chr5q33.1 | chromosome location | human chr5q33.1 | 31 | 2 | 26134 | 50 |
RPS14,CD74 |
1.628e-03 | -6.42 | lower_leg | COSMIC cancer mutations | lower_leg | 174 | 4 | 16828 | 49 |
DCC,ADAM28,NTRK1,CSF1R |
1.632e-03 | -6.42 | EXOSC4 (exosome component 4) | protein interactions | 54512 | 197 | 4 | 19454 | 50 |
RPL37A,IVNS1ABP,RPL18A,NTRK1 |
1.649e-03 | -6.41 | positive regulation of cell adhesion mediated by integrin | biological process | GO:0033630 | 22 | 2 | 18204 | 50 |
SYK,PTPN6 |
1.649e-03 | -6.41 | Fc receptor mediated stimulatory signaling pathway | biological process | GO:0002431 | 22 | 2 | 18204 | 50 |
HCK,SYK |
1.656e-03 | -6.40 | RAB5A (RAB5A, member RAS oncogene family) | protein interactions | 5868 | 679 | 7 | 19454 | 50 |
RPL12,RPL18A,ITM2B,RPL13A,RPL37A,SPECC1,RPL27A |
1.663e-03 | -6.40 | ZC3H10 (zinc finger CCCH-type containing 10) | protein interactions | 84872 | 198 | 4 | 19454 | 50 |
RPL8,RPL14,RPL37A,RPL13A |
1.668e-03 | -6.40 | positive regulation of hydrolase activity | biological process | GO:0051345 | 466 | 6 | 18204 | 50 |
PSAP,SYK,CTSS,NTRK1,ARAP1,RAPGEF6 |
1.672e-03 | -6.39 | NCBP1 (nuclear cap binding protein subunit 1) | protein interactions | 4686 | 336 | 5 | 19454 | 50 |
NTRK1,RPS3A,RPS20,RBM47,IVNS1ABP |
1.675e-03 | -6.39 | central_nervous_system-medulla-primitive_neuroectodermal_tumour-medulloblastoma | COSMIC cancer mutations | central_nervous_system-medulla-primitive_neuroectodermal_tumour-medulloblastoma | 14773 | 49 | 16828 | 49 |
NTRK1,HIPK2,GAB1,RPL37A,ITM2B,CTSS,ITGAX,DIAPH2,FCHO2,ENTPD1,RPL14,RPL36A,ELMO1,RPL12,RPL34,CD74,SYK,GNAI2,RBM47,RXRA,SPECC1,RPS26,PDZRN3,RPS3A,PSAP,RPS25,SH2B3,CARD10,RPL13A,RPL35,HCK,CADPS2,IVNS1ABP,RPL8,RPL18A,PTPN6,ARAP1,CSF1R,PDE6D,RPL27A,RAPGEF6,MAN1C1,RPS14,ADAM28,SLC13A1,RPS20,DCC,RGL1,BMP2K |
1.675e-03 | -6.39 | central_nervous_system-medulla-primitive_neuroectodermal_tumour-medulloblastoma-classic | COSMIC cancer mutations | central_nervous_system-medulla-primitive_neuroectodermal_tumour-medulloblastoma-classic | 14773 | 49 | 16828 | 49 |
PDE6D,CSF1R,ARAP1,RPL27A,RPL8,RPL18A,PTPN6,IVNS1ABP,HCK,CADPS2,RPL35,RGL1,BMP2K,SLC13A1,RPS20,DCC,ADAM28,RPS14,RAPGEF6,MAN1C1,RPL34,CD74,GNAI2,RBM47,SYK,RPL36A,RPL14,ENTPD1,RPL12,ELMO1,ITGAX,FCHO2,DIAPH2,NTRK1,ITM2B,HIPK2,RPL37A,GAB1,CTSS,SH2B3,CARD10,PSAP,RPS25,RPL13A,PDZRN3,RPS3A,SPECC1,RPS26,RXRA |
1.675e-03 | -6.39 | central_nervous_system-medulla-primitive_neuroectodermal_tumour-medulloblastoma-desmoplastic | COSMIC cancer mutations | central_nervous_system-medulla-primitive_neuroectodermal_tumour-medulloblastoma-desmoplastic | 14773 | 49 | 16828 | 49 |
ELMO1,RPL12,RPL14,ENTPD1,RPL36A,SYK,GNAI2,RBM47,CD74,RPL34,RPL37A,ITM2B,GAB1,HIPK2,CTSS,NTRK1,ITGAX,DIAPH2,FCHO2,RPS3A,PDZRN3,RPL13A,PSAP,RPS25,SH2B3,CARD10,RXRA,RPS26,SPECC1,RPL18A,PTPN6,RPL8,RPL27A,CSF1R,ARAP1,PDE6D,RPL35,HCK,CADPS2,IVNS1ABP,DCC,SLC13A1,RPS20,BMP2K,RGL1,MAN1C1,RAPGEF6,RPS14,ADAM28 |
1.675e-03 | -6.39 | central_nervous_system-medulla-primitive_neuroectodermal_tumour-medulloblastoma-large_cell | COSMIC cancer mutations | central_nervous_system-medulla-primitive_neuroectodermal_tumour-medulloblastoma-large_cell | 14773 | 49 | 16828 | 49 |
RPL36A,ENTPD1,RPL14,RPL12,ELMO1,CD74,RPL34,RBM47,GNAI2,SYK,NTRK1,CTSS,GAB1,HIPK2,RPL37A,ITM2B,FCHO2,DIAPH2,ITGAX,PDZRN3,RPS3A,CARD10,SH2B3,RPS25,PSAP,RPL13A,RXRA,SPECC1,RPS26,RPL8,PTPN6,RPL18A,CSF1R,PDE6D,ARAP1,RPL27A,RPL35,IVNS1ABP,CADPS2,HCK,RPS20,SLC13A1,DCC,RGL1,BMP2K,RAPGEF6,MAN1C1,ADAM28,RPS14 |
1.681e-03 | -6.39 | classic | COSMIC cancer mutations | classic | 14774 | 49 | 16828 | 49 |
PDE6D,ARAP1,CSF1R,RPL27A,RPL8,PTPN6,RPL18A,IVNS1ABP,CADPS2,HCK,RPL35,RGL1,BMP2K,RPS20,SLC13A1,DCC,ADAM28,RPS14,RAPGEF6,MAN1C1,CD74,RPL34,RBM47,GNAI2,SYK,RPL36A,ENTPD1,RPL14,RPL12,ELMO1,FCHO2,DIAPH2,ITGAX,NTRK1,CTSS,GAB1,RPL37A,HIPK2,ITM2B,CARD10,SH2B3,RPS25,PSAP,RPL13A,PDZRN3,RPS3A,SPECC1,RPS26,RXRA |
1.694e-03 | -6.38 | BYSL (bystin like) | protein interactions | 705 | 337 | 5 | 19454 | 50 |
RPS14,RPS25,RPS26,RPS20,RPS3A |
1.704e-03 | -6.38 | medulla | COSMIC cancer mutations | medulla | 14778 | 49 | 16828 | 49 |
RXRA,RPS26,SPECC1,RPS3A,PDZRN3,RPL13A,RPS25,PSAP,CARD10,SH2B3,CTSS,GAB1,HIPK2,ITM2B,RPL37A,NTRK1,DIAPH2,FCHO2,ITGAX,ELMO1,RPL12,ENTPD1,RPL14,RPL36A,SYK,RBM47,GNAI2,CD74,RPL34,MAN1C1,RAPGEF6,RPS14,ADAM28,DCC,RPS20,SLC13A1,BMP2K,RGL1,RPL35,CADPS2,HCK,IVNS1ABP,PTPN6,RPL18A,RPL8,RPL27A,CSF1R,PDE6D,ARAP1 |
1.709e-03 | -6.37 | desmoplastic | COSMIC cancer mutations | desmoplastic | 14779 | 49 | 16828 | 49 |
IVNS1ABP,CADPS2,HCK,RPL35,RPL27A,ARAP1,CSF1R,PDE6D,PTPN6,RPL18A,RPL8,ADAM28,RPS14,MAN1C1,RAPGEF6,BMP2K,RGL1,DCC,RPS20,SLC13A1,FCHO2,DIAPH2,ITGAX,CTSS,RPL37A,GAB1,ITM2B,HIPK2,NTRK1,RBM47,GNAI2,SYK,CD74,RPL34,RPL12,ELMO1,RPL36A,ENTPD1,RPL14,RPS26,SPECC1,RXRA,RPL13A,CARD10,SH2B3,RPS25,PSAP,RPS3A,PDZRN3 |
1.713e-03 | -6.37 | NRAS (NRAS proto-oncogene, GTPase) | protein interactions | 4893 | 683 | 7 | 19454 | 50 |
ITM2B,FYB1,RPS20,RGL1,SPECC1,GAB1,RAPGEF6 |
1.724e-03 | -6.36 | positive regulation of immune response | biological process | GO:0050778 | 640 | 7 | 18204 | 50 |
CD74,HCK,CTSS,PTPN6,SYK,RBM47,FYB1 |
1.757e-03 | -6.34 | TRAF4 (TNF receptor associated factor 4) | protein interactions | 9618 | 201 | 4 | 19454 | 50 |
RPL14,RPL18A,NTRK1,RPL27A |
1.759e-03 | -6.34 | PRMT1 (protein arginine methyltransferase 1) | protein interactions | 3276 | 886 | 8 | 19454 | 50 |
NTRK1,RPL37A,RPL14,RPS14,RPS3A,RPL13A,RPL8,IVNS1ABP |
1.776e-03 | -6.33 | Prot_kinase_dom | interpro domains | IPR000719 | 480 | 6 | 18521 | 50 |
HIPK2,BMP2K,HCK,SYK,NTRK1,CSF1R |
1.796e-03 | -6.32 | Regulation of KIT signaling | REACTOME pathways | R-HSA-1433559 | 16 | 2 | 10285 | 41 |
PTPN6,SH2B3 |
1.799e-03 | -6.32 | positive regulation of MAPK cascade | biological process | GO:0043410 | 473 | 6 | 18204 | 50 |
CD74,GNAI2,SYK,CSF1R,HIPK2,NTRK1 |
1.803e-03 | -6.32 | megakaryocyte development | biological process | GO:0035855 | 23 | 2 | 18204 | 50 |
PTPN6,SH2B3 |
1.817e-03 | -6.31 | TSPYL2 (TSPY like 2) | protein interactions | 64061 | 94 | 3 | 19454 | 50 |
RPL18A,RPS25,RPL27A |
1.829e-03 | -6.30 | RHOU (ras homolog family member U) | protein interactions | 58480 | 507 | 6 | 19454 | 50 |
SPECC1,GAB1,ITM2B,FCHO2,SYK,GNAI2 |
1.865e-03 | -6.28 | PH | pfam domains | PF00169 | 187 | 4 | 17795 | 50 |
ARAP1,SH2B3,GAB1,CADPS2 |
1.865e-03 | -6.28 | H1-4 (H1.4 linker histone, cluster member) | protein interactions | 3008 | 509 | 6 | 19454 | 50 |
RPS20,RPL13A,RPS3A,RPL12,RPL14,RPL37A |
1.890e-03 | -6.27 | - | gene3d domains | 2.30.30.30 | 20 | 2 | 14470 | 47 |
RPL14,RPL8 |
1.909e-03 | -6.26 | mRNA 5'-UTR binding | molecular function | GO:0048027 | 24 | 2 | 18094 | 49 |
RPS14,RPS3A |
1.912e-03 | -6.26 | SOX2 (SRY-box transcription factor 2) | protein interactions | 6657 | 1342 | 10 | 19454 | 50 |
RPL34,RPS14,RPS20,RPL27A,RPL18A,RPL12,RPL8,GNAI2,RPL13A,RPS3A |
1.913e-03 | -6.26 | human chr7p14.2-p14.1 | chromosome location | human chr7p14.2-p14.1 | 1 | 1 | 26134 | 50 |
ELMO1 |
1.917e-03 | -6.26 | Thromboxane A2 receptor signaling | Pathway Interaction DB | txa2pathway | 45 | 3 | 2226 | 13 |
SYK,HCK,GNAI2 |
1.929e-03 | -6.25 | THAP7 (THAP domain containing 7) | protein interactions | 80764 | 96 | 3 | 19454 | 50 |
RPL18A,RPS3A,RPL13A |
1.974e-03 | -6.23 | PRRC2A (proline rich coiled-coil 2A) | protein interactions | 7916 | 349 | 5 | 19454 | 50 |
NTRK1,RPS20,CD74,PTPN6,RBM47 |
1.987e-03 | -6.22 | Tpm1 (tropomyosin 1, alpha) | protein interactions | 22003 | 97 | 3 | 19454 | 50 |
SPECC1,BMP2K,GNAI2 |
1.987e-03 | -6.22 | CBLB (Cbl proto-oncogene B) | protein interactions | 868 | 97 | 3 | 19454 | 50 |
NTRK1,SYK,FYB1 |
1.997e-03 | -6.22 | ovary-carcinoma-mucinous_carcinoma | COSMIC cancer mutations | ovary-carcinoma-mucinous_carcinoma | 456 | 6 | 16828 | 49 |
HIPK2,NTRK1,BMP2K,SYK,CSF1R,HCK |
2.023e-03 | -6.20 | ZNF320 (zinc finger protein 320) | protein interactions | 162967 | 26 | 2 | 19454 | 50 |
RPL27A,RPL34 |
2.025e-03 | -6.20 | lipid binding | molecular function | GO:0008289 | 861 | 8 | 18094 | 49 |
RAPGEF6,ARAP1,RXRA,PSAP,CADPS2,FYB1,FCHO2,HCK |
2.041e-03 | -6.19 | phosphoprotein binding | molecular function | GO:0051219 | 93 | 3 | 18094 | 49 |
PTPN6,SYK,HCK |
2.042e-03 | -6.19 | mucinous_carcinoma | COSMIC cancer mutations | mucinous_carcinoma | 458 | 6 | 16828 | 49 |
BMP2K,HIPK2,SYK,NTRK1,CSF1R,HCK |
2.045e-03 | -6.19 | RasGEFN | smart domains | SM00229 | 20 | 2 | 9717 | 33 |
RGL1,RAPGEF6 |
2.047e-03 | -6.19 | VAV2 (vav guanine nucleotide exchange factor 2) | protein interactions | 7410 | 98 | 3 | 19454 | 50 |
SYK,GAB1,NTRK1 |
2.047e-03 | -6.19 | Snd1 (staphylococcal nuclease and tudor domain containing 1) | protein interactions | 56463 | 98 | 3 | 19454 | 50 |
RPL8,RPL14,RPL34 |
2.047e-03 | -6.19 | PRPSAP2 (phosphoribosyl pyrophosphate synthetase associated protein 2) | protein interactions | 5636 | 98 | 3 | 19454 | 50 |
HCK,IVNS1ABP,NTRK1 |
2.047e-03 | -6.19 | MAP4K5 (mitogen-activated protein kinase kinase kinase kinase 5) | protein interactions | 11183 | 98 | 3 | 19454 | 50 |
HCK,RPL34,NTRK1 |
2.057e-03 | -6.19 | IL-3 Signaling Pathway | WikiPathways | WP286 | 49 | 3 | 5310 | 28 |
PTPN6,HCK,SYK |
2.097e-03 | -6.17 | EXOSC10 (exosome component 10) | protein interactions | 5394 | 211 | 4 | 19454 | 50 |
NTRK1,PTPN6,RPL18A,SYK |
2.107e-03 | -6.16 | NOD2 (nucleotide binding oligomerization domain containing 2) | protein interactions | 64127 | 99 | 3 | 19454 | 50 |
RPL13A,RPL37A,RPL34 |
2.107e-03 | -6.16 | URB2 (URB2 ribosome biogenesis homolog) | protein interactions | 9816 | 99 | 3 | 19454 | 50 |
RPL14,RPL18A,RPL13A |
2.107e-03 | -6.16 | ZBTB11 (zinc finger and BTB domain containing 11) | protein interactions | 27107 | 99 | 3 | 19454 | 50 |
RPL8,RPL35,RPL13A |
2.107e-03 | -6.16 | Flnb (filamin, beta) | protein interactions | 286940 | 99 | 3 | 19454 | 50 |
BMP2K,SPECC1,FCHO2 |
2.107e-03 | -6.16 | PRPSAP1 (phosphoribosyl pyrophosphate synthetase associated protein 1) | protein interactions | 5635 | 99 | 3 | 19454 | 50 |
HCK,RPL35,IVNS1ABP |
2.127e-03 | -6.15 | large_cell | COSMIC cancer mutations | large_cell | 14845 | 49 | 16828 | 49 |
RXRA,SPECC1,RPS26,PDZRN3,RPS3A,PSAP,RPS25,SH2B3,CARD10,RPL13A,NTRK1,ITM2B,GAB1,RPL37A,HIPK2,CTSS,ITGAX,DIAPH2,FCHO2,ENTPD1,RPL14,RPL36A,ELMO1,RPL12,RPL34,CD74,SYK,GNAI2,RBM47,RAPGEF6,MAN1C1,RPS14,ADAM28,SLC13A1,RPS20,DCC,RGL1,BMP2K,RPL35,HCK,CADPS2,IVNS1ABP,RPL8,RPL18A,PTPN6,ARAP1,CSF1R,PDE6D,RPL27A |
2.153e-03 | -6.14 | lysosomal lumen | cellular component | GO:0043202 | 98 | 3 | 19108 | 50 |
PSAP,CD74,CTSS |
2.154e-03 | -6.14 | positive regulation of ERK1 and ERK2 cascade | biological process | GO:0070374 | 199 | 4 | 18204 | 50 |
CD74,CSF1R,NTRK1,GNAI2 |
2.168e-03 | -6.13 | RANBP6 (RAN binding protein 6) | protein interactions | 26953 | 100 | 3 | 19454 | 50 |
RPL35,RPL27A,NTRK1 |
2.168e-03 | -6.13 | REPS1 (RALBP1 associated Eps domain containing 1) | protein interactions | 85021 | 100 | 3 | 19454 | 50 |
BMP2K,RXRA,NTRK1 |
2.168e-03 | -6.13 | HRAS (HRas proto-oncogene, GTPase) | protein interactions | 3265 | 712 | 7 | 19454 | 50 |
PDE6D,RAPGEF6,RGL1,GAB1,SPECC1,ITM2B,FCHO2 |
2.179e-03 | -6.13 | ovary-carcinoma-endometrioid_carcinoma | COSMIC cancer mutations | ovary-carcinoma-endometrioid_carcinoma | 464 | 6 | 16828 | 49 |
NTRK1,HIPK2,CSF1R,HCK,SYK,BMP2K |
2.181e-03 | -6.13 | OLIG1 (oligodendrocyte transcription factor 1) | protein interactions | 116448 | 27 | 2 | 19454 | 50 |
PTPN6,HCK |
2.181e-03 | -6.13 | SLA (Src like adaptor) | protein interactions | 6503 | 27 | 2 | 19454 | 50 |
SYK,GAB1 |
2.181e-03 | -6.13 | CD72 (CD72 molecule) | protein interactions | 971 | 27 | 2 | 19454 | 50 |
PTPN6,SYK |
2.198e-03 | -6.12 | follicular_lymphoma | COSMIC cancer mutations | follicular_lymphoma | 1209 | 10 | 16828 | 49 |
CTSS,RXRA,ENTPD1,NTRK1,DIAPH2,ITGAX,GNAI2,SYK,IVNS1ABP,HCK |
2.205e-03 | -6.12 | NEDD8 (NEDD8 ubiquitin like modifier) | protein interactions | 4738 | 358 | 5 | 19454 | 50 |
RPL35,RPL8,RPS3A,CSF1R,RPS20 |
2.230e-03 | -6.11 | NELFCD (negative elongation factor complex member C/D) | protein interactions | 51497 | 101 | 3 | 19454 | 50 |
RPS14,RPS26,NTRK1 |
2.238e-03 | -6.10 | breast-carcinoma-ER-PR-positive_carcinoma | COSMIC cancer mutations | breast-carcinoma-ER-PR-positive_carcinoma | 1881 | 13 | 16828 | 49 |
PTPN6,ELMO1,SYK,RPS25,CSF1R,CARD10,RGL1,GAB1,NTRK1,RAPGEF6,ITGAX,SPECC1,IVNS1ABP |
2.238e-03 | -6.10 | ER-PR-positive_carcinoma | COSMIC cancer mutations | ER-PR-positive_carcinoma | 1881 | 13 | 16828 | 49 |
GAB1,RAPGEF6,NTRK1,ITGAX,IVNS1ABP,SPECC1,ELMO1,PTPN6,SYK,CARD10,RGL1,RPS25,CSF1R |
2.278e-03 | -6.08 | Regulation of signaling by CBL | REACTOME pathways | R-HSA-912631 | 18 | 2 | 10285 | 41 |
SYK,HCK |
2.283e-03 | -6.08 | MRPL2 (mitochondrial ribosomal protein L2) | protein interactions | 51069 | 216 | 4 | 19454 | 50 |
RPL35,RPS3A,RPL27A,RPL13A |
2.294e-03 | -6.08 | BBX (BBX high mobility group box domain containing) | protein interactions | 56987 | 102 | 3 | 19454 | 50 |
RPL18A,RPL27A,RPL13A |
2.294e-03 | -6.08 | GRAP2 (GRB2 related adaptor protein 2) | protein interactions | 9402 | 102 | 3 | 19454 | 50 |
SYK,GAB1,CSF1R |
2.337e-03 | -6.06 | regulation of apoptotic process | biological process | GO:0042981 | 1518 | 11 | 18204 | 50 |
CARD10,NTRK1,CSF1R,HIPK2,RPS3A,IVNS1ABP,CTSS,PTPN6,GNAI2,CD74,HCK |
2.345e-03 | -6.06 | ZNF430 (zinc finger protein 430) | protein interactions | 80264 | 28 | 2 | 19454 | 50 |
RPL27A,RPS14 |
2.358e-03 | -6.05 | SRBD1 (S1 RNA binding domain 1) | protein interactions | 55133 | 103 | 3 | 19454 | 50 |
RPL18A,NTRK1,RPL27A |
2.363e-03 | -6.05 | VCP (valosin containing protein) | protein interactions | 7415 | 1381 | 10 | 19454 | 50 |
RPS25,RPL27A,NTRK1,RPL35,RPL13A,RXRA,RPS3A,RPL18A,RPL12,RPL8 |
2.370e-03 | -6.05 | SLC25A5 (solute carrier family 25 member 5) | protein interactions | 292 | 364 | 5 | 19454 | 50 |
RPL14,RPL37A,NTRK1,RPS3A,RBM47 |
2.387e-03 | -6.04 | regulation of molecular function | biological process | GO:0065009 | 2005 | 13 | 18204 | 50 |
SYK,CTSS,RXRA,CD74,NTRK1,CARD10,ARAP1,CSF1R,PSAP,GNAI2,HCK,HIPK2,RAPGEF6 |
2.427e-03 | -6.02 | LYAR (Ly1 antibody reactive) | protein interactions | 55646 | 366 | 5 | 19454 | 50 |
SYK,RPL18A,RPL37A,RPL13A,RPS3A |
2.449e-03 | -6.01 | protein phosphorylation | biological process | GO:0006468 | 503 | 6 | 18204 | 50 |
SYK,PTPN6,HCK,NTRK1,CSF1R,HIPK2 |
2.455e-03 | -6.01 | NTRK3 (neurotrophic receptor tyrosine kinase 3) | protein interactions | 4916 | 367 | 5 | 19454 | 50 |
ITM2B,NTRK1,RAPGEF6,GAB1,FCHO2 |
2.462e-03 | -6.01 | positive regulation of response to stimulus | biological process | GO:0048584 | 2266 | 14 | 18204 | 50 |
GNAI2,PTPN6,HCK,RPS20,RBM47,HIPK2,SYK,CTSS,RXRA,CD74,NTRK1,FYB1,CSF1R,BMP2K |
2.480e-03 | -6.00 | GTF3C1 (general transcription factor IIIC subunit 1) | protein interactions | 2975 | 221 | 4 | 19454 | 50 |
SYK,CD74,NTRK1,RPL27A |
2.491e-03 | -6.00 | MED9 (mediator complex subunit 9) | protein interactions | 55090 | 105 | 3 | 19454 | 50 |
RPS3A,RPL8,GNAI2 |
2.501e-03 | -5.99 | Son of sevenless (SoS) protein Chain: S domain 1 | gene3d domains | 1.20.870.10 | 23 | 2 | 14470 | 47 |
RGL1,RAPGEF6 |
2.520e-03 | -5.98 | MRPL44 (mitochondrial ribosomal protein L44) | protein interactions | 65080 | 222 | 4 | 19454 | 50 |
NTRK1,RPL27A,RBM47,RPL13A |
2.520e-03 | -5.98 | PDGFRB (platelet derived growth factor receptor beta) | protein interactions | 5159 | 222 | 4 | 19454 | 50 |
GAB1,CSF1R,NTRK1,PTPN6 |
2.534e-03 | -5.98 | FUS (FUS RNA binding protein) | protein interactions | 2521 | 732 | 7 | 19454 | 50 |
RPL12,RPS26,RXRA,RPL14,RPS14,RPS20,NTRK1 |
2.543e-03 | -5.97 | DBN1 (drebrin 1) | protein interactions | 1627 | 370 | 5 | 19454 | 50 |
NTRK1,FCHO2,CARD10,SPECC1,BMP2K |
2.570e-03 | -5.96 | pparg.L (peroxisome proliferator activated receptor gamma L homeolog) | protein interactions | 397769 | 1 | 1 | 19454 | 50 |
RXRA |
2.570e-03 | -5.96 | sina (seven in absentia) | protein interactions | 39884 | 1 | 1 | 19454 | 50 |
DCC |
2.570e-03 | -5.96 | Parp1 (poly (ADP-ribose) polymerase 1) | protein interactions | 25591 | 1 | 1 | 19454 | 50 |
RXRA |
2.570e-03 | -5.96 | ZNF285 (zinc finger protein 285) | protein interactions | 26974 | 1 | 1 | 19454 | 50 |
CARD10 |
2.570e-03 | -5.96 | SIAH1P1 (siah E3 ubiquitin protein ligase 1 pseudogene 1) | protein interactions | 340571 | 1 | 1 | 19454 | 50 |
HIPK2 |
2.603e-03 | -5.95 | ARAF (A-Raf proto-oncogene, serine/threonine kinase) | protein interactions | 369 | 372 | 5 | 19454 | 50 |
RPS3A,RPS25,RPS14,RPL12,RPL34 |
2.603e-03 | -5.95 | NHLRC2 (NHL repeat containing 2) | protein interactions | 374354 | 372 | 5 | 19454 | 50 |
SYK,RPL35,GNAI2,ITGAX,NTRK1 |
2.603e-03 | -5.95 | U2AF1 (U2 small nuclear RNA auxiliary factor 1) | protein interactions | 7307 | 224 | 4 | 19454 | 50 |
NTRK1,PSAP,RPS14,RPL37A |
2.614e-03 | -5.95 | hematopoietic progenitor cell differentiation | biological process | GO:0002244 | 100 | 3 | 18204 | 50 |
PTPN6,RBM47,SH2B3 |
2.617e-03 | -5.95 | NOS2-CD74 complex | cellular component | GO:0035693 | 1 | 1 | 19108 | 50 |
CD74 |
2.633e-03 | -5.94 | MYO6 (myosin VI) | protein interactions | 4646 | 373 | 5 | 19454 | 50 |
CTSS,NTRK1,FCHO2,CARD10,BMP2K |
2.645e-03 | -5.93 | EIF2S2 (eukaryotic translation initiation factor 2 subunit beta) | protein interactions | 8894 | 225 | 4 | 19454 | 50 |
PTPN6,NTRK1,DCC,RPL37A |
2.664e-03 | -5.93 | RAD21 (RAD21 cohesin complex component) | protein interactions | 5885 | 374 | 5 | 19454 | 50 |
RPS14,RPS3A,NTRK1,RPS20,RPS25 |
2.689e-03 | -5.92 | platelet activation | biological process | GO:0030168 | 101 | 3 | 18204 | 50 |
ENTPD1,SYK,PTPN6 |
2.690e-03 | -5.92 | CSF3R (colony stimulating factor 3 receptor) | protein interactions | 1441 | 30 | 2 | 19454 | 50 |
HCK,SYK |
2.690e-03 | -5.92 | PECAM1 (platelet and endothelial cell adhesion molecule 1) | protein interactions | 5175 | 30 | 2 | 19454 | 50 |
PTPN6,HCK |
2.695e-03 | -5.92 | NF2 (NF2, moesin-ezrin-radixin like (MERLIN) tumor suppressor) | protein interactions | 4771 | 375 | 5 | 19454 | 50 |
RPS3A,RPL13A,RPL8,RPL14,RPL18A |
2.698e-03 | -5.92 | AGO4 (argonaute RISC component 4) | protein interactions | 192670 | 108 | 3 | 19454 | 50 |
RPL35,RPS26,RPL27A |
2.700e-03 | -5.91 | Ribosomal_eS26 | interpro domains | IPR000892 | 1 | 1 | 18521 | 50 |
RPS26 |
2.700e-03 | -5.91 | Ribosomal_uL2_arc | interpro domains | IPR023672 | 1 | 1 | 18521 | 50 |
RPL8 |
2.700e-03 | -5.91 | BMP2K_C | interpro domains | IPR028182 | 1 | 1 | 18521 | 50 |
BMP2K |
2.700e-03 | -5.91 | Ribosomal_uS10_CS | interpro domains | IPR018268 | 1 | 1 | 18521 | 50 |
RPS20 |
2.700e-03 | -5.91 | Ribosomal_uL29_sf | interpro domains | IPR036049 | 1 | 1 | 18521 | 50 |
RPL35 |
2.700e-03 | -5.91 | RBM47_RRM3 | interpro domains | IPR034445 | 1 | 1 | 18521 | 50 |
RBM47 |
2.700e-03 | -5.91 | Ribosomal_eL34 | interpro domains | IPR008195 | 1 | 1 | 18521 | 50 |
RPL34 |
2.700e-03 | -5.91 | Ribosomal_uL15_CS | interpro domains | IPR001196 | 1 | 1 | 18521 | 50 |
RPL27A |
2.700e-03 | -5.91 | Rbsml_uL15_N | interpro domains | IPR027386 | 1 | 1 | 18521 | 50 |
RPL27A |
2.700e-03 | -5.91 | Ribosomal_eL34_CS | interpro domains | IPR018065 | 1 | 1 | 18521 | 50 |
RPL34 |
2.700e-03 | -5.91 | RGL1_RA | interpro domains | IPR030748 | 1 | 1 | 18521 | 50 |
RGL1 |
2.700e-03 | -5.91 | FCHo2_F-BAR | interpro domains | IPR030122 | 1 | 1 | 18521 | 50 |
FCHO2 |
2.700e-03 | -5.91 | Ribosomal_eL14 | interpro domains | IPR039660 | 1 | 1 | 18521 | 50 |
RPL14 |
2.700e-03 | -5.91 | Ribosomal_eS25 | interpro domains | IPR004977 | 1 | 1 | 18521 | 50 |
RPS25 |
2.700e-03 | -5.91 | HCK_SH2 | interpro domains | IPR035851 | 1 | 1 | 18521 | 50 |
HCK |
2.700e-03 | -5.91 | SH2B3_SH2 | interpro domains | IPR035059 | 1 | 1 | 18521 | 50 |
SH2B3 |
2.700e-03 | -5.91 | Ribosomal_uL11_CS | interpro domains | IPR020785 | 1 | 1 | 18521 | 50 |
RPL12 |
2.700e-03 | -5.91 | FYB_hSH3 | interpro domains | IPR035540 | 1 | 1 | 18521 | 50 |
FYB1 |
2.700e-03 | -5.91 | MHC_II-assoc_invariant_trimer | interpro domains | IPR011988 | 1 | 1 | 18521 | 50 |
CD74 |
2.700e-03 | -5.91 | Ribosomal_uL29_CS | interpro domains | IPR018254 | 1 | 1 | 18521 | 50 |
RPL35 |
2.700e-03 | -5.91 | Ribosomal_uL13_euk/arc | interpro domains | IPR005755 | 1 | 1 | 18521 | 50 |
RPL13A |
2.700e-03 | -5.91 | Ribosomal_eS1 | interpro domains | IPR001593 | 1 | 1 | 18521 | 50 |
RPS3A |
2.700e-03 | -5.91 | MHC_II-assoc_invar/CLIP_MHC-bd | interpro domains | IPR015386 | 1 | 1 | 18521 | 50 |
CD74 |
2.700e-03 | -5.91 | Ribosomal_eL20_eukaryotes | interpro domains | IPR021138 | 1 | 1 | 18521 | 50 |
RPL18A |
2.700e-03 | -5.91 | Ribosomal_eL14_dom | interpro domains | IPR002784 | 1 | 1 | 18521 | 50 |
RPL14 |
2.700e-03 | -5.91 | Ribosomal_eS1_CS | interpro domains | IPR018281 | 1 | 1 | 18521 | 50 |
RPS3A |
2.700e-03 | -5.91 | TrkA_TMD | interpro domains | IPR040665 | 1 | 1 | 18521 | 50 |
NTRK1 |
2.700e-03 | -5.91 | MHCII_invariant_trimer_sf | interpro domains | IPR036613 | 1 | 1 | 18521 | 50 |
CD74 |
2.700e-03 | -5.91 | CSF-1_receptor | interpro domains | IPR030658 | 1 | 1 | 18521 | 50 |
CSF1R |
2.700e-03 | -5.91 | MHC_II-assoc_invar_chain | interpro domains | IPR022339 | 1 | 1 | 18521 | 50 |
CD74 |
2.700e-03 | -5.91 | Ribosomal_eL43 | interpro domains | IPR002674 | 1 | 1 | 18521 | 50 |
RPL37A |
2.700e-03 | -5.91 | Ribosomal_eL20 | interpro domains | IPR028877 | 1 | 1 | 18521 | 50 |
RPL18A |
2.700e-03 | -5.91 | Ribosomal_uL29 | interpro domains | IPR001854 | 1 | 1 | 18521 | 50 |
RPL35 |
2.700e-03 | -5.91 | Ribosomal_eL20_dom | interpro domains | IPR023573 | 1 | 1 | 18521 | 50 |
RPL18A |
2.700e-03 | -5.91 | Ribosomal_uL2_CS | interpro domains | IPR022671 | 1 | 1 | 18521 | 50 |
RPL8 |
2.700e-03 | -5.91 | CD74_antigen | interpro domains | IPR043530 | 1 | 1 | 18521 | 50 |
CD74 |
2.700e-03 | -5.91 | Ribosomal_uS10 | interpro domains | IPR001848 | 1 | 1 | 18521 | 50 |
RPS20 |
2.700e-03 | -5.91 | Ribosomal_uS10_euk/arc | interpro domains | IPR005729 | 1 | 1 | 18521 | 50 |
RPS20 |
2.700e-03 | -5.91 | RBM47_RRM1 | interpro domains | IPR047044 | 1 | 1 | 18521 | 50 |
RBM47 |
2.700e-03 | -5.91 | Rhodop-sen_GMP-Pdiesterase_dsu | interpro domains | IPR017287 | 1 | 1 | 18521 | 50 |
PDE6D |
2.700e-03 | -5.91 | Ribosomal_uL29_euk | interpro domains | IPR045059 | 1 | 1 | 18521 | 50 |
RPL35 |
2.700e-03 | -5.91 | Ribosomal_eS26_sf | interpro domains | IPR038551 | 1 | 1 | 18521 | 50 |
RPS26 |
2.700e-03 | -5.91 | Ribosomal_uL2_dom3 | interpro domains | IPR014726 | 1 | 1 | 18521 | 50 |
RPL8 |
2.700e-03 | -5.91 | Ribosomal_eS1_euk | interpro domains | IPR027500 | 1 | 1 | 18521 | 50 |
RPS3A |
2.700e-03 | -5.91 | Ribosomal_eL14_KOW | interpro domains | IPR041985 | 1 | 1 | 18521 | 50 |
RPL14 |
2.700e-03 | -5.91 | NTRK1 | interpro domains | IPR020461 | 1 | 1 | 18521 | 50 |
NTRK1 |
2.700e-03 | -5.91 | RBM47_RRM2 | interpro domains | IPR034440 | 1 | 1 | 18521 | 50 |
RBM47 |
2.700e-03 | -5.91 | CARD_CARD10 | interpro domains | IPR042140 | 1 | 1 | 18521 | 50 |
CARD10 |
2.700e-03 | -5.91 | Ribosomal_eS26_CS | interpro domains | IPR047864 | 1 | 1 | 18521 | 50 |
RPS26 |
2.708e-03 | -5.91 | ganglioside GP1c binding | molecular function | GO:1905577 | 1 | 1 | 18094 | 49 |
PSAP |
2.708e-03 | -5.91 | MHC class II protein binding, via antigen binding groove | molecular function | GO:0042658 | 1 | 1 | 18094 | 49 |
CD74 |
2.708e-03 | -5.91 | neurotrophin p75 receptor binding | molecular function | GO:0005166 | 1 | 1 | 18094 | 49 |
NTRK1 |
2.708e-03 | -5.91 | ITPase activity | molecular function | GO:0103023 | 1 | 1 | 18094 | 49 |
ENTPD1 |
2.708e-03 | -5.91 | ganglioside GM3 binding | molecular function | GO:1905575 | 1 | 1 | 18094 | 49 |
PSAP |
2.708e-03 | -5.91 | interleukin-15 receptor binding | molecular function | GO:0016170 | 1 | 1 | 18094 | 49 |
SYK |
2.708e-03 | -5.91 | ganglioside GM2 binding | molecular function | GO:1905574 | 1 | 1 | 18094 | 49 |
PSAP |
2.730e-03 | -5.90 | Kinase-like_dom_sf | interpro domains | IPR011009 | 523 | 6 | 18521 | 50 |
HCK,HIPK2,SYK,BMP2K,NTRK1,CSF1R |
2.747e-03 | -5.90 | positive regulation of endothelial tube morphogenesis | biological process | GO:1905956 | 1 | 1 | 18204 | 50 |
ITGAX |
2.747e-03 | -5.90 | positive regulation of interleukin-3 production | biological process | GO:0032752 | 1 | 1 | 18204 | 50 |
SYK |
2.747e-03 | -5.90 | negative regulation of formation of translation preinitiation complex | biological process | GO:1901194 | 1 | 1 | 18204 | 50 |
RPL13A |
2.747e-03 | -5.90 | negative regulation of adenylate cyclase-activating adrenergic receptor signaling pathway involved in heart process | biological process | GO:0140199 | 1 | 1 | 18204 | 50 |
GNAI2 |
2.747e-03 | -5.90 | ganglioside GM1 transport to membrane | biological process | GO:1905572 | 1 | 1 | 18204 | 50 |
PSAP |
2.747e-03 | -5.90 | positive regulation of beta-galactosidase activity | biological process | GO:1903771 | 1 | 1 | 18204 | 50 |
PSAP |
2.747e-03 | -5.90 | regulation of formation of translation preinitiation complex | biological process | GO:1901193 | 1 | 1 | 18204 | 50 |
RPL13A |
2.747e-03 | -5.90 | macrophage migration inhibitory factor signaling pathway | biological process | GO:0035691 | 1 | 1 | 18204 | 50 |
CD74 |
2.774e-03 | -5.89 | testis-germ_cell_tumour-non_seminoma | COSMIC cancer mutations | testis-germ_cell_tumour-non_seminoma | 487 | 6 | 16828 | 49 |
HCK,CSF1R,NTRK1,SYK,BMP2K,HIPK2 |
2.775e-03 | -5.89 | GRN (granulin precursor) | protein interactions | 2896 | 228 | 4 | 19454 | 50 |
NTRK1,PSAP,SLC13A1,RAPGEF6 |
2.786e-03 | -5.88 | positive regulation of cell communication | biological process | GO:0010647 | 1792 | 12 | 18204 | 50 |
RXRA,CD74,SYK,CTSS,CSF1R,BMP2K,NTRK1,GNAI2,PTPN6,RBM47,HIPK2,RPS20 |
2.802e-03 | -5.88 | rRNA processing | biological process | GO:0006364 | 214 | 4 | 18204 | 50 |
RPL35,RPS14,RPL14,RPS25 |
2.805e-03 | -5.88 | human chr9q33.3 | chromosome location | human chr9q33.3 | 41 | 2 | 26134 | 50 |
RPL12,RPL35 |
2.810e-03 | -5.87 | MHC2-interact | pfam domains | PF09307 | 1 | 1 | 17795 | 50 |
CD74 |
2.810e-03 | -5.87 | TrkA_TMD | pfam domains | PF18613 | 1 | 1 | 17795 | 50 |
NTRK1 |
2.810e-03 | -5.87 | Ribosomal_L18A | pfam domains | PF01775 | 1 | 1 | 17795 | 50 |
RPL18A |
2.810e-03 | -5.87 | MHCassoc_trimer | pfam domains | PF08831 | 1 | 1 | 17795 | 50 |
CD74 |
2.810e-03 | -5.87 | Ribosomal_L14e | pfam domains | PF01929 | 1 | 1 | 17795 | 50 |
RPL14 |
2.810e-03 | -5.87 | Ribosomal_S26e | pfam domains | PF01283 | 1 | 1 | 17795 | 50 |
RPS26 |
2.810e-03 | -5.87 | Ribosomal_S3Ae | pfam domains | PF01015 | 1 | 1 | 17795 | 50 |
RPS3A |
2.810e-03 | -5.87 | Ribosomal_L37ae | pfam domains | PF01780 | 1 | 1 | 17795 | 50 |
RPL37A |
2.810e-03 | -5.87 | Ribosomal_L34e | pfam domains | PF01199 | 1 | 1 | 17795 | 50 |
RPL34 |
2.810e-03 | -5.87 | Ribosomal_S25 | pfam domains | PF03297 | 1 | 1 | 17795 | 50 |
RPS25 |
2.810e-03 | -5.87 | Ribosomal_L29 | pfam domains | PF00831 | 1 | 1 | 17795 | 50 |
RPL35 |
2.810e-03 | -5.87 | BMP2K_C | pfam domains | PF15282 | 1 | 1 | 17795 | 50 |
BMP2K |
2.811e-03 | -5.87 | RASGEF_NTER | prosite domains | PS50212 | 22 | 2 | 12186 | 44 |
RAPGEF6,RGL1 |
2.823e-03 | -5.87 | skin-knee-malignant_melanoma | COSMIC cancer mutations | skin-knee-malignant_melanoma | 97 | 3 | 16828 | 49 |
DCC,NTRK1,ADAM28 |
2.835e-03 | -5.87 | peptidyl-amino acid modification | biological process | GO:0018193 | 518 | 6 | 18204 | 50 |
HCK,HIPK2,CSF1R,NTRK1,SYK,PTPN6 |
2.843e-03 | -5.86 | erythrocyte differentiation | biological process | GO:0030218 | 103 | 3 | 18204 | 50 |
SH2B3,RPS14,HIPK2 |
2.843e-03 | -5.86 | ribosomal small subunit biogenesis | biological process | GO:0042274 | 103 | 3 | 18204 | 50 |
RPS3A,RPS14,RPS25 |
2.863e-03 | -5.86 | regulation of platelet aggregation | biological process | GO:0090330 | 29 | 2 | 18204 | 50 |
SYK,SH2B3 |
2.863e-03 | -5.86 | LARP4B (La ribonucleoprotein 4B) | protein interactions | 23185 | 230 | 4 | 19454 | 50 |
RBM47,RPS20,RPS3A,NTRK1 |
2.864e-03 | -5.86 | regulation of body fluid levels | biological process | GO:0050878 | 356 | 5 | 18204 | 50 |
ENTPD1,SH2B3,SYK,GNAI2,PTPN6 |
2.870e-03 | -5.85 | MEGF10 (multiple EGF like domains 10) | protein interactions | 84466 | 31 | 2 | 19454 | 50 |
SYK,CADPS2 |
2.885e-03 | -5.85 | ABT1 (activator of basal transcription 1) | protein interactions | 29777 | 381 | 5 | 19454 | 50 |
RPL13A,RPS3A,RPL35,RPL37A,RPL14 |
2.908e-03 | -5.84 | KRT17 (keratin 17) | protein interactions | 3872 | 231 | 4 | 19454 | 50 |
RPS25,RPS20,RPL14,RPL12 |
2.916e-03 | -5.84 | Signaling events mediated by Stem cell factor receptor (c-Kit) | Pathway Interaction DB | kitpathway | 52 | 3 | 2226 | 13 |
SH2B3,PTPN6,GAB1 |
2.919e-03 | -5.84 | non_seminoma | COSMIC cancer mutations | non_seminoma | 492 | 6 | 16828 | 49 |
NTRK1,HIPK2,CSF1R,HCK,BMP2K,SYK |
2.922e-03 | -5.84 | regulation of chemokine production | biological process | GO:0032642 | 104 | 3 | 18204 | 50 |
CSF1R,CD74,SYK |
2.948e-03 | -5.83 | skin-carcinoma-squamous_cell_carcinoma | COSMIC cancer mutations | skin-carcinoma-squamous_cell_carcinoma | 493 | 6 | 16828 | 49 |
BMP2K,SYK,SH2B3,CSF1R,SPECC1,NTRK1 |
2.951e-03 | -5.83 | enzyme binding | molecular function | GO:0019899 | 2086 | 13 | 18094 | 49 |
SYK,RBM47,PTPN6,DIAPH2,RXRA,NTRK1,PDE6D,PSAP,ITGAX,SH2B3,RAPGEF6,CSF1R,CD74 |
2.954e-03 | -5.82 | EIF3D (eukaryotic translation initiation factor 3 subunit D) | protein interactions | 8664 | 232 | 4 | 19454 | 50 |
NTRK1,CD74,RPS20,RPL35 |
2.961e-03 | -5.82 | Ras_GEF_dom_sf | interpro domains | IPR023578 | 30 | 2 | 18521 | 50 |
RAPGEF6,RGL1 |
2.961e-03 | -5.82 | RASGEF_cat_dom_sf | interpro domains | IPR036964 | 30 | 2 | 18521 | 50 |
RGL1,RAPGEF6 |
2.961e-03 | -5.82 | RASGEF_cat_dom | interpro domains | IPR001895 | 30 | 2 | 18521 | 50 |
RAPGEF6,RGL1 |
2.991e-03 | -5.81 | GLG1 (golgi glycoprotein 1) | protein interactions | 2734 | 112 | 3 | 19454 | 50 |
NTRK1,ITM2B,SYK |
2.993e-03 | -5.81 | RasGEF | pfam domains | PF00617 | 29 | 2 | 17795 | 50 |
RAPGEF6,RGL1 |
3.002e-03 | -5.81 | response to type II interferon | biological process | GO:0034341 | 105 | 3 | 18204 | 50 |
HCK,CD74,RPL13A |
3.046e-03 | -5.79 | EIF3L (eukaryotic translation initiation factor 3 subunit L) | protein interactions | 51386 | 234 | 4 | 19454 | 50 |
NTRK1,CD74,RPS20,RPS25 |
3.046e-03 | -5.79 | EPHA1 (EPH receptor A1) | protein interactions | 2041 | 234 | 4 | 19454 | 50 |
RPL14,RPL27A,RPS20,RPL13A |
3.046e-03 | -5.79 | JAK1 (Janus kinase 1) | protein interactions | 3716 | 234 | 4 | 19454 | 50 |
GAB1,SYK,PTPN6,NTRK1 |
3.057e-03 | -5.79 | UBL3 (ubiquitin like 3) | protein interactions | 5412 | 32 | 2 | 19454 | 50 |
PSAP,PDE6D |
3.057e-03 | -5.79 | RASA3 (RAS p21 protein activator 3) | protein interactions | 22821 | 32 | 2 | 19454 | 50 |
GNAI2,HCK |
3.062e-03 | -5.79 | regulation of superoxide metabolic process | biological process | GO:0090322 | 30 | 2 | 18204 | 50 |
GNAI2,SYK |
3.062e-03 | -5.79 | megakaryocyte differentiation | biological process | GO:0030219 | 30 | 2 | 18204 | 50 |
PTPN6,SH2B3 |
3.081e-03 | -5.78 | human chr1q25.3 | chromosome location | human chr1q25.3 | 43 | 2 | 26134 | 50 |
RGL1,IVNS1ABP |
3.085e-03 | -5.78 | COPS6 (COP9 signalosome subunit 6) | protein interactions | 10980 | 387 | 5 | 19454 | 50 |
PSAP,NTRK1,RPS20,RPL8,RPS14 |
3.094e-03 | -5.78 | regulation of peptidyl-tyrosine phosphorylation | biological process | GO:0050730 | 220 | 4 | 18204 | 50 |
SYK,PTPN6,CD74,CSF1R |
3.141e-03 | -5.76 | CTSL (cathepsin L) | protein interactions | 1514 | 236 | 4 | 19454 | 50 |
RXRA,PSAP,CD74,ITM2B |
3.141e-03 | -5.76 | NMRAL1 (NmrA like redox sensor 1) | protein interactions | 57407 | 236 | 4 | 19454 | 50 |
RPL8,GNAI2,RPL14,RPS3A |
3.144e-03 | -5.76 | organic substance metabolic process | biological process | GO:0071704 | 7613 | 31 | 18204 | 50 |
RXRA,CD74,RPL37A,RPL13A,CTSS,IVNS1ABP,PDZRN3,CSF1R,ADAM28,RPL8,ENTPD1,PTPN6,RPS26,RPS3A,RPS14,RPL34,RPS25,RPS20,SYK,RPL35,MAN1C1,NTRK1,RPL14,RPL27A,RPL12,HCK,RPL18A,PSAP,RBM47,HIPK2,RPL36A |
3.166e-03 | -5.76 | regulation of signal transduction by p53 class mediator | biological process | GO:1901796 | 107 | 3 | 18204 | 50 |
RPS20,HIPK2,CD74 |
3.199e-03 | -5.75 | nucleolus | cellular component | GO:0005730 | 1414 | 10 | 19108 | 50 |
RPL12,RPS14,SPECC1,RPS25,RPL13A,RPL34,RPS3A,PTPN6,DIAPH2,RPL35 |
3.221e-03 | -5.74 | negative regulation of apoptotic process | biological process | GO:0043066 | 914 | 8 | 18204 | 50 |
GNAI2,HCK,CD74,NTRK1,IVNS1ABP,RPS3A,HIPK2,CSF1R |
3.224e-03 | -5.74 | lung-carcinoid-endocrine_tumour | COSMIC cancer mutations | lung-carcinoid-endocrine_tumour | 502 | 6 | 16828 | 49 |
CSF1R,HCK,BMP2K,SYK,NTRK1,HIPK2 |
3.248e-03 | -5.73 | - | gene3d domains | 6.10.250.3250 | 1 | 1 | 14470 | 47 |
RPL13A |
3.248e-03 | -5.73 | - | gene3d domains | 4.10.990.10 | 1 | 1 | 14470 | 47 |
RPL27A |
3.248e-03 | -5.73 | Ribosomal protein S26e | gene3d domains | 3.30.1740.20 | 1 | 1 | 14470 | 47 |
RPS26 |
3.248e-03 | -5.73 | - | gene3d domains | 6.20.340.10 | 1 | 1 | 14470 | 47 |
RPL34 |
3.248e-03 | -5.73 | Ribosomal protein L2, domain 3 | gene3d domains | 4.10.950.10 | 1 | 1 | 14470 | 47 |
RPL8 |
3.248e-03 | -5.73 | - | gene3d domains | 1.10.287.310 | 1 | 1 | 14470 | 47 |
RPL35 |
3.248e-03 | -5.73 | - | gene3d domains | 6.20.370.60 | 1 | 1 | 14470 | 47 |
PDZRN3 |
3.248e-03 | -5.73 | - | gene3d domains | 6.20.370.70 | 1 | 1 | 14470 | 47 |
RPL34 |
3.248e-03 | -5.73 | MHC class II-associated invariant chain, trimerisation domain | gene3d domains | 1.10.870.10 | 1 | 1 | 14470 | 47 |
CD74 |
3.248e-03 | -5.73 | - | gene3d domains | 6.10.250.2270 | 1 | 1 | 14470 | 47 |
RPL14 |
3.248e-03 | -5.73 | - | gene3d domains | 6.10.250.3450 | 1 | 1 | 14470 | 47 |
RPL35 |
3.267e-03 | -5.72 | antigen processing and presentation of exogenous peptide antigen via MHC class II | biological process | GO:0019886 | 31 | 2 | 18204 | 50 |
CD74,CTSS |
3.301e-03 | -5.71 | activation of immune response | biological process | GO:0002253 | 368 | 5 | 18204 | 50 |
HCK,CTSS,FYB1,PTPN6,SYK |
3.301e-03 | -5.71 | immune response-regulating signaling pathway | biological process | GO:0002764 | 368 | 5 | 18204 | 50 |
HCK,SYK,FYB1,CTSS,PTPN6 |
3.302e-03 | -5.71 | ZNF629 (zinc finger protein 629) | protein interactions | 23361 | 116 | 3 | 19454 | 50 |
RPL13A,NTRK1,RPL14 |
3.326e-03 | -5.71 | UTP and CTP dephosphorylation I | BIOCYC pathways | META_PWY-7185 | 3 | 1 | 902 | 1 |
ENTPD1 |
3.326e-03 | -5.71 | UTP and CTP dephosphorylation II | BIOCYC pathways | META_PWY-7177 | 3 | 1 | 902 | 1 |
ENTPD1 |
3.367e-03 | -5.69 | PRKCA (protein kinase C alpha) | protein interactions | 5578 | 395 | 5 | 19454 | 50 |
SYK,IVNS1ABP,PTPN6,PSAP,NTRK1 |
3.396e-03 | -5.69 | Ribosomal_S3Ae | smart domains | SM01397 | 1 | 1 | 9717 | 33 |
RPS3A |
3.401e-03 | -5.68 | Protein_kinase_ATP_BS | interpro domains | IPR017441 | 377 | 5 | 18521 | 50 |
HCK,HIPK2,SYK,NTRK1,CSF1R |
3.404e-03 | -5.68 | MAPK3 (mitogen-activated protein kinase 3) | protein interactions | 5595 | 396 | 5 | 19454 | 50 |
GAB1,SYK,DCC,RXRA,NTRK1 |
3.418e-03 | -5.68 | lung-carcinoid-endocrine_tumour-atypical | COSMIC cancer mutations | lung-carcinoid-endocrine_tumour-atypical | 508 | 6 | 16828 | 49 |
BMP2K,SYK,CSF1R,HCK,HIPK2,NTRK1 |
3.444e-03 | -5.67 | RIBOSOMALS10 | prints domains | PR00971 | 1 | 1 | 5227 | 18 |
RPS20 |
3.444e-03 | -5.67 | NTKRECEPTOR1 | prints domains | PR01940 | 1 | 1 | 5227 | 18 |
NTRK1 |
3.444e-03 | -5.67 | RIBOSOMALL34 | prints domains | PR01250 | 1 | 1 | 5227 | 18 |
RPL34 |
3.444e-03 | -5.67 | CD74ANTIGEN | prints domains | PR01990 | 1 | 1 | 5227 | 18 |
CD74 |
3.446e-03 | -5.67 | GDAP1 (ganglioside induced differentiation associated protein 1) | protein interactions | 54332 | 34 | 2 | 19454 | 50 |
NTRK1,PSAP |
3.446e-03 | -5.67 | ELMO1 (engulfment and cell motility 1) | protein interactions | 9844 | 34 | 2 | 19454 | 50 |
HCK,NTRK1 |
3.479e-03 | -5.66 | Fc-gamma receptor signaling pathway | biological process | GO:0038094 | 32 | 2 | 18204 | 50 |
HCK,SYK |
3.516e-03 | -5.65 | nuclear lumen | cellular component | GO:0031981 | 4888 | 22 | 19108 | 50 |
RXRA,IVNS1ABP,RPL35,RPS26,DIAPH2,RPS20,HIPK2,RPS3A,CADPS2,RPL34,CSF1R,RPL13A,ARAP1,RPS25,RPS14,RPL8,PTPN6,SPECC1,RPL27A,BMP2K,GNAI2,RPL12 |
3.516e-03 | -5.65 | immune response-activating cell surface receptor signaling pathway | biological process | GO:0002429 | 228 | 4 | 18204 | 50 |
HCK,FYB1,PTPN6,SYK |
3.538e-03 | -5.64 | PES1 (pescadillo ribosomal biogenesis factor 1) | protein interactions | 23481 | 244 | 4 | 19454 | 50 |
RPL8,RPL18A,RPL27A,NTRK1 |
3.538e-03 | -5.64 | XRN1 (5'-3' exoribonuclease 1) | protein interactions | 54464 | 244 | 4 | 19454 | 50 |
NTRK1,RPL13A,RPL8,RPL14 |
3.546e-03 | -5.64 | signaling adaptor activity | molecular function | GO:0035591 | 113 | 3 | 18094 | 49 |
SH2B3,CARD10,GAB1 |
3.548e-03 | -5.64 | NOP9 (NOP9 nucleolar protein) | protein interactions | 161424 | 119 | 3 | 19454 | 50 |
RPS3A,RBM47,RPS14 |
3.578e-03 | -5.63 | phosphorylation | biological process | GO:0016310 | 729 | 7 | 18204 | 50 |
HCK,PTPN6,SYK,CSF1R,BMP2K,HIPK2,NTRK1 |
3.601e-03 | -5.63 | erythrocyte homeostasis | biological process | GO:0034101 | 112 | 3 | 18204 | 50 |
SH2B3,RPS14,HIPK2 |
3.608e-03 | -5.62 | Neurotrophic factor-mediated Trk receptor signaling | Pathway Interaction DB | trkrpathway | 56 | 3 | 2226 | 13 |
NTRK1,GAB1,ELMO1 |
3.611e-03 | -5.62 | RIBOSOMAL_S26E | prosite domains | PS00733 | 1 | 1 | 12186 | 44 |
RPS26 |
3.611e-03 | -5.62 | RIBOSOMAL_L29 | prosite domains | PS00579 | 1 | 1 | 12186 | 44 |
RPL35 |
3.611e-03 | -5.62 | RIBOSOMAL_L11 | prosite domains | PS00359 | 1 | 1 | 12186 | 44 |
RPL12 |
3.611e-03 | -5.62 | RIBOSOMAL_L34E | prosite domains | PS01145 | 1 | 1 | 12186 | 44 |
RPL34 |
3.611e-03 | -5.62 | RIBOSOMAL_L2 | prosite domains | PS00467 | 1 | 1 | 12186 | 44 |
RPL8 |
3.611e-03 | -5.62 | RIBOSOMAL_S3AE | prosite domains | PS01191 | 1 | 1 | 12186 | 44 |
RPS3A |
3.611e-03 | -5.62 | RIBOSOMAL_L15 | prosite domains | PS00475 | 1 | 1 | 12186 | 44 |
RPL27A |
3.611e-03 | -5.62 | RIBOSOMAL_S10 | prosite domains | PS00361 | 1 | 1 | 12186 | 44 |
RPS20 |
3.649e-03 | -5.61 | IL2RB (interleukin 2 receptor subunit beta) | protein interactions | 3560 | 35 | 2 | 19454 | 50 |
SYK,PTPN6 |
3.649e-03 | -5.61 | Mbp (myelin basic protein) | protein interactions | 17196 | 35 | 2 | 19454 | 50 |
FYB1,HCK |
3.649e-03 | -5.61 | RGS19 (regulator of G protein signaling 19) | protein interactions | 10287 | 35 | 2 | 19454 | 50 |
NTRK1,GNAI2 |
3.655e-03 | -5.61 | atypical | COSMIC cancer mutations | atypical | 515 | 6 | 16828 | 49 |
NTRK1,HIPK2,HCK,CSF1R,SYK,BMP2K |
3.693e-03 | -5.60 | LGALS9 (galectin 9) | protein interactions | 3965 | 584 | 6 | 19454 | 50 |
RPL18A,RPL8,RPL14,RPS14,RPL13A,RPS3A |
3.696e-03 | -5.60 | PICALM (phosphatidylinositol binding clathrin assembly protein) | protein interactions | 8301 | 247 | 4 | 19454 | 50 |
RBM47,NTRK1,FCHO2,BMP2K |
3.696e-03 | -5.60 | DDX50 (DExD-box helicase 50) | protein interactions | 79009 | 247 | 4 | 19454 | 50 |
RPL18A,RPL8,RPL35,RPL13A |
3.697e-03 | -5.60 | antigen processing and presentation of peptide antigen via MHC class II | biological process | GO:0002495 | 33 | 2 | 18204 | 50 |
CTSS,CD74 |
3.697e-03 | -5.60 | negative regulation of inflammatory response to antigenic stimulus | biological process | GO:0002862 | 33 | 2 | 18204 | 50 |
SYK,HCK |
3.715e-03 | -5.60 | cellular response to cytokine stimulus | biological process | GO:0071345 | 734 | 7 | 18204 | 50 |
CD74,HCK,PTPN6,RPL13A,SYK,CSF1R,SH2B3 |
3.803e-03 | -5.57 | anion binding | molecular function | GO:0043168 | 2412 | 14 | 18094 | 49 |
SYK,HIPK2,ENTPD1,ARAP1,ITM2B,NTRK1,BMP2K,RXRA,PSAP,HCK,FCHO2,GNAI2,CSF1R,RAPGEF6 |
3.803e-03 | -5.57 | MYO19 (myosin XIX) | protein interactions | 80179 | 249 | 4 | 19454 | 50 |
CARD10,FCHO2,SPECC1,BMP2K |
3.808e-03 | -5.57 | ORF1ab (ORF1a polyprotein;ORF1ab polyprotein) | protein interactions | 43740578 | 3416 | 17 | 19454 | 50 |
CADPS2,CARD10,RPS20,RPL8,PDZRN3,FCHO2,RPL18A,RPL12,RPS3A,PSAP,RPL13A,RPL14,RPL35,RPS25,IVNS1ABP,ARAP1,RPS26 |
3.819e-03 | -5.57 | actin filament | cellular component | GO:0005884 | 120 | 3 | 19108 | 50 |
HCK,SPECC1,DIAPH2 |
3.857e-03 | -5.56 | Trim69 (tripartite motif-containing 69) | protein interactions | 70928 | 36 | 2 | 19454 | 50 |
GNAI2,SPECC1 |
3.866e-03 | -5.56 | cell adhesion molecule binding | molecular function | GO:0050839 | 560 | 6 | 18094 | 49 |
RPL14,RPL34,ITGAX,PTPN6,SYK,RPS26 |
3.885e-03 | -5.55 | XPO1 (exportin 1) | protein interactions | 7514 | 1479 | 10 | 19454 | 50 |
NTRK1,RPS25,RPS14,RPL35,BMP2K,RAPGEF6,RPS3A,RPL8,RPL18A,FCHO2 |
3.921e-03 | -5.54 | regulation of B cell differentiation | biological process | GO:0045577 | 34 | 2 | 18204 | 50 |
SYK,PTPN6 |
3.921e-03 | -5.54 | antigen processing and presentation of peptide or polysaccharide antigen via MHC class II | biological process | GO:0002504 | 34 | 2 | 18204 | 50 |
CTSS,CD74 |
3.972e-03 | -5.53 | negative regulation of programmed cell death | biological process | GO:0043069 | 946 | 8 | 18204 | 50 |
CD74,HCK,GNAI2,CSF1R,RPS3A,HIPK2,IVNS1ABP,NTRK1 |
3.982e-03 | -5.53 | EPS15L1 (epidermal growth factor receptor pathway substrate 15 like 1) | protein interactions | 58513 | 124 | 3 | 19454 | 50 |
NTRK1,FCHO2,IVNS1ABP |
3.982e-03 | -5.53 | TNK2 (tyrosine kinase non receptor 2) | protein interactions | 10188 | 124 | 3 | 19454 | 50 |
NTRK1,HCK,RPL18A |
4.025e-03 | -5.52 | PRRC2C (proline rich coiled-coil 2C) | protein interactions | 23215 | 253 | 4 | 19454 | 50 |
RPS20,CD74,RBM47,NTRK1 |
4.046e-03 | -5.51 | HNRNPC (heterogeneous nuclear ribonucleoprotein C) | protein interactions | 3183 | 595 | 6 | 19454 | 50 |
NTRK1,RPS3A,PSAP,RBM47,IVNS1ABP,HCK |
4.071e-03 | -5.50 | CD22 (CD22 molecule) | protein interactions | 933 | 37 | 2 | 19454 | 50 |
SYK,PTPN6 |
4.108e-03 | -5.49 | regulation of catalytic activity | biological process | GO:0050790 | 1395 | 10 | 18204 | 50 |
RAPGEF6,ARAP1,CSF1R,NTRK1,CARD10,CD74,PSAP,SYK,GNAI2,CTSS |
4.112e-03 | -5.49 | FYN (FYN proto-oncogene, Src family tyrosine kinase) | protein interactions | 2534 | 414 | 5 | 19454 | 50 |
IVNS1ABP,DCC,SYK,FYB1,CSF1R |
4.152e-03 | -5.48 | positive regulation of myeloid leukocyte cytokine production involved in immune response | biological process | GO:0061081 | 35 | 2 | 18204 | 50 |
CD74,SYK |
4.154e-03 | -5.48 | SNIP1 (Smad nuclear interacting protein 1) | protein interactions | 79753 | 415 | 5 | 19454 | 50 |
RPS14,RPL14,RPL35,RPL34,RPS3A |
4.165e-03 | -5.48 | PRR11 (proline rich 11) | protein interactions | 55771 | 126 | 3 | 19454 | 50 |
RPL18A,RPS3A,RPL13A |
4.165e-03 | -5.48 | MRPL55 (mitochondrial ribosomal protein L55) | protein interactions | 128308 | 126 | 3 | 19454 | 50 |
RPL27A,RPL13A,RPL35 |
4.165e-03 | -5.48 | GBA1 (glucosylceramidase beta 1) | protein interactions | 2629 | 126 | 3 | 19454 | 50 |
BMP2K,PSAP,NTRK1 |
4.233e-03 | -5.46 | haematopoietic_and_lymphoid_tissue-haematopoietic_neoplasm-myelodysplastic-myeloproliferative_neoplasm-unclassifiable | COSMIC cancer mutations | haematopoietic_and_lymphoid_tissue-haematopoietic_neoplasm-myelodysplastic-myeloproliferative_neoplasm-unclassifiable | 112 | 3 | 16828 | 49 |
CSF1R,SH2B3,HIPK2 |
4.233e-03 | -5.46 | myelodysplastic-myeloproliferative_neoplasm-unclassifiable | COSMIC cancer mutations | myelodysplastic-myeloproliferative_neoplasm-unclassifiable | 112 | 3 | 16828 | 49 |
HIPK2,SH2B3,CSF1R |
4.239e-03 | -5.46 | Ras guanine-nucleotide exchange factors catalytic domain | gene3d domains | 1.10.840.10 | 30 | 2 | 14470 | 47 |
RAPGEF6,RGL1 |
4.251e-03 | -5.46 | TYRKINASE | prints domains | PR00109 | 98 | 3 | 5227 | 18 |
HCK,NTRK1,SYK |
4.258e-03 | -5.46 | MRPL32 (mitochondrial ribosomal protein L32) | protein interactions | 64983 | 127 | 3 | 19454 | 50 |
RPL13A,RPL27A,RPL35 |
4.288e-03 | -5.45 | RA | smart domains | SM00314 | 29 | 2 | 9717 | 33 |
RGL1,RAPGEF6 |
4.304e-03 | -5.45 | positive regulation of response to external stimulus | biological process | GO:0032103 | 564 | 6 | 18204 | 50 |
CSF1R,CD74,HCK,RBM47,CTSS,SYK |
4.352e-03 | -5.44 | MYB (MYB proto-oncogene, transcription factor) | protein interactions | 4602 | 128 | 3 | 19454 | 50 |
RPL34,HIPK2,RPL37A |
4.352e-03 | -5.44 | BTK (Bruton tyrosine kinase) | protein interactions | 695 | 128 | 3 | 19454 | 50 |
HCK,SYK,GAB1 |
4.388e-03 | -5.43 | regulation of homotypic cell-cell adhesion | biological process | GO:0034110 | 36 | 2 | 18204 | 50 |
SH2B3,SYK |
4.435e-03 | -5.42 | UTP and CTP dephosphorylation II | BIOCYC pathways | HUMAN_PWY-7177 | 4 | 1 | 902 | 1 |
ENTPD1 |
4.448e-03 | -5.42 | EIF2B4 (eukaryotic translation initiation factor 2B subunit delta) | protein interactions | 8890 | 129 | 3 | 19454 | 50 |
DCC,NTRK1,CD74 |
4.472e-03 | -5.41 | protein kinase activity | molecular function | GO:0004672 | 577 | 6 | 18094 | 49 |
NTRK1,HCK,BMP2K,SYK,CSF1R,HIPK2 |
4.585e-03 | -5.39 | RasGEF | smart domains | SM00147 | 30 | 2 | 9717 | 33 |
RAPGEF6,RGL1 |
4.638e-03 | -5.37 | TRAF6 (TNF receptor associated factor 6) | protein interactions | 7189 | 426 | 5 | 19454 | 50 |
RPS20,PTPN6,NTRK1,RXRA,SYK |
4.643e-03 | -5.37 | EIF2B1 (eukaryotic translation initiation factor 2B subunit alpha) | protein interactions | 1967 | 131 | 3 | 19454 | 50 |
DCC,RBM47,NTRK1 |
4.649e-03 | -5.37 | metabolic process | biological process | GO:0008152 | 8139 | 32 | 18204 | 50 |
ENTPD1,PTPN6,RPS3A,RPS14,RPS26,RPS20,RPS25,RPL34,CD74,RXRA,CTSS,RPL13A,RPL37A,CSF1R,ADAM28,PDZRN3,IVNS1ABP,RPL8,HCK,RPL12,PSAP,RPL18A,HIPK2,RPL36A,RBM47,SYK,BMP2K,RPL35,RPL27A,RPL14,NTRK1,MAN1C1 |
4.672e-03 | -5.37 | rRNA metabolic process | biological process | GO:0016072 | 247 | 4 | 18204 | 50 |
RPL14,RPS25,RPL35,RPS14 |
4.679e-03 | -5.36 | PFKP (phosphofructokinase, platelet) | protein interactions | 5214 | 264 | 4 | 19454 | 50 |
GAB1,NTRK1,CTSS,PTPN6 |
4.684e-03 | -5.36 | STAT3 (signal transducer and activator of transcription 3) | protein interactions | 6774 | 427 | 5 | 19454 | 50 |
NTRK1,RXRA,IVNS1ABP,SYK,HCK |
4.686e-03 | -5.36 | positive regulation of protein phosphorylation | biological process | GO:0001934 | 574 | 6 | 18204 | 50 |
SYK,CD74,CARD10,NTRK1,HIPK2,CSF1R |
4.689e-03 | -5.36 | MOV10 (Mov10 RNA helicase) | protein interactions | 4343 | 1273 | 9 | 19454 | 50 |
RPS26,RBM47,RPL12,SYK,NTRK1,RPL35,CARD10,RPL34,RAPGEF6 |
4.742e-03 | -5.35 | MYEF2 (myelin expression factor 2) | protein interactions | 50804 | 132 | 3 | 19454 | 50 |
RPL37A,RPL14,NTRK1 |
4.742e-03 | -5.35 | EIF2A (eukaryotic translation initiation factor 2A) | protein interactions | 83939 | 132 | 3 | 19454 | 50 |
RPS20,NTRK1,DCC |
4.744e-03 | -5.35 | PHLDB1 (pleckstrin homology like domain family B member 1) | protein interactions | 23187 | 40 | 2 | 19454 | 50 |
RPS25,NTRK1 |
4.750e-03 | -5.35 | MATR3 (matrin 3) | protein interactions | 9782 | 615 | 6 | 19454 | 50 |
NTRK1,RPS3A,RXRA,RPL13A,RPL8,RPL14 |
4.785e-03 | -5.34 | Fcgamma receptor (FCGR) dependent phagocytosis | REACTOME pathways | R-HSA-2029480 | 86 | 3 | 10285 | 41 |
HCK,ELMO1,SYK |
4.815e-03 | -5.34 | kidney-Wilms_tumour | COSMIC cancer mutations | kidney-Wilms_tumour | 545 | 6 | 16828 | 49 |
NTRK1,HCK,CSF1R,SYK,BMP2K,HIPK2 |
4.837e-03 | -5.33 | Transferase(Phosphotransferase) domain 1 | gene3d domains | 1.10.510.10 | 490 | 6 | 14470 | 47 |
BMP2K,SYK,HIPK2,HCK,NTRK1,CSF1R |
4.858e-03 | -5.33 | Wilms_tumour | COSMIC cancer mutations | Wilms_tumour | 546 | 6 | 16828 | 49 |
NTRK1,HIPK2,CSF1R,HCK,BMP2K,SYK |
4.863e-03 | -5.33 | RASGEF_CAT | prosite domains | PS50009 | 29 | 2 | 12186 | 44 |
RAPGEF6,RGL1 |
4.869e-03 | -5.32 | organelle lumen | cellular component | GO:0043233 | 6022 | 25 | 19108 | 50 |
RPL8,GNAI2,RPL12,RPL35,IVNS1ABP,RPS26,DIAPH2,RPS20,CADPS2,RPS3A,RPL34,CTSS,RPS14,ARAP1,PTPN6,BMP2K,SPECC1,RPL27A,PSAP,RXRA,CD74,HIPK2,CSF1R,RPL13A,RPS25 |
4.869e-03 | -5.32 | membrane-enclosed lumen | cellular component | GO:0031974 | 6022 | 25 | 19108 | 50 |
PTPN6,SPECC1,RPL27A,BMP2K,PSAP,HIPK2,RXRA,CD74,RPL13A,RPS25,CSF1R,RPL8,GNAI2,RPL12,DIAPH2,RPS20,RPS3A,CADPS2,RPL35,IVNS1ABP,RPS26,ARAP1,RPS14,CTSS,RPL34 |
4.869e-03 | -5.32 | intracellular organelle lumen | cellular component | GO:0070013 | 6022 | 25 | 19108 | 50 |
ARAP1,RPS14,RPL34,CTSS,RPS20,DIAPH2,RPS3A,CADPS2,IVNS1ABP,RPL35,RPS26,GNAI2,RPL12,RPL8,RPL13A,RPS25,CSF1R,HIPK2,RXRA,CD74,SPECC1,BMP2K,RPL27A,PSAP,PTPN6 |
4.939e-03 | -5.31 | FBL (fibrillarin) | protein interactions | 2091 | 620 | 6 | 19454 | 50 |
RPS14,RPL8,RPL18A,RPS3A,NTRK1,RPL13A |
5.004e-03 | -5.30 | extracellular space | cellular component | GO:0005615 | 3443 | 17 | 19108 | 50 |
GNAI2,RPL12,PSAP,RPL37A,PTPN6,ITM2B,ENTPD1,RPS25,RPS14,MAN1C1,RPL34,CTSS,RPS20,RPL14,RPS3A,CD74,RPS26 |
5.095e-03 | -5.28 | positive regulation of immune system process | biological process | GO:0002684 | 986 | 8 | 18204 | 50 |
PTPN6,CTSS,SYK,CD74,HCK,FYB1,CSF1R,RBM47 |
5.131e-03 | -5.27 | POP1 (POP1 homolog, ribonuclease P/MRP subunit) | protein interactions | 10940 | 271 | 4 | 19454 | 50 |
SYK,RPL8,RPL13A,NTRK1 |
5.134e-03 | -5.27 | Nherf2 (NHERF family PDZ scaffold protein 2) | protein interactions | 65962 | 2 | 1 | 19454 | 50 |
SLC13A1 |
5.134e-03 | -5.27 | Arl3 (ADP-ribosylation factor-like 3) | protein interactions | 56350 | 2 | 1 | 19454 | 50 |
PDE6D |
5.134e-03 | -5.27 | Pdzk1 (PDZ domain containing 1) | protein interactions | 59020 | 2 | 1 | 19454 | 50 |
SLC13A1 |
5.134e-03 | -5.27 | OR10G4 (olfactory receptor family 10 subfamily G member 4) | protein interactions | 390264 | 2 | 1 | 19454 | 50 |
RPL12 |
5.134e-03 | -5.27 | KIR2DL5A (killer cell immunoglobulin like receptor, two Ig domains and long cytoplasmic tail 5A) | protein interactions | 57292 | 2 | 1 | 19454 | 50 |
PTPN6 |
5.134e-03 | -5.27 | Arl2 (ADP-ribosylation factor-like 2) | protein interactions | 56327 | 2 | 1 | 19454 | 50 |
PDE6D |
5.134e-03 | -5.27 | Dvl3 (dishevelled segment polarity protein 3) | protein interactions | 13544 | 2 | 1 | 19454 | 50 |
PDZRN3 |
5.134e-03 | -5.27 | Erbb3 (erb-b2 receptor tyrosine kinase 3) | protein interactions | 29496 | 2 | 1 | 19454 | 50 |
RPL13A |
5.134e-03 | -5.27 | MPIG6B (megakaryocyte and platelet inhibitory receptor G6b) | protein interactions | 80739 | 2 | 1 | 19454 | 50 |
PTPN6 |
5.134e-03 | -5.27 | CUZD1 (CUB and zona pellucida like domains 1) | protein interactions | 50624 | 2 | 1 | 19454 | 50 |
PTPN6 |
5.134e-03 | -5.27 | Rgs13 (regulator of G-protein signaling 13) | protein interactions | 246709 | 2 | 1 | 19454 | 50 |
GNAI2 |
5.134e-03 | -5.27 | Siglece (sialic acid binding Ig-like lectin E) | protein interactions | 83382 | 2 | 1 | 19454 | 50 |
PTPN6 |
5.153e-03 | -5.27 | DNTTIP2 (deoxynucleotidyltransferase terminal interacting protein 2) | protein interactions | 30836 | 136 | 3 | 19454 | 50 |
RXRA,RPL13A,RPL35 |
5.199e-03 | -5.26 | APP (amyloid beta precursor protein) | protein interactions | 351 | 2342 | 13 | 19454 | 50 |
ARAP1,CD74,ITM2B,RPS26,HCK,SYK,RPS25,RPS14,RPL34,RGL1,RPL12,RPS20,RPL37A |
5.227e-03 | -5.25 | CSF1-CSF1R complex | cellular component | GO:1990682 | 2 | 1 | 19108 | 50 |
CSF1R |
5.227e-03 | -5.25 | macrophage migration inhibitory factor receptor complex | cellular component | GO:0035692 | 2 | 1 | 19108 | 50 |
CD74 |
5.227e-03 | -5.25 | integrin alphaX-beta2 complex | cellular component | GO:0034689 | 2 | 1 | 19108 | 50 |
ITGAX |
5.231e-03 | -5.25 | regulation of B cell activation | biological process | GO:0050864 | 128 | 3 | 18204 | 50 |
CD74,PTPN6,SYK |
5.262e-03 | -5.25 | GBF1 (golgi brefeldin A resistant guanine nucleotide exchange factor 1) | protein interactions | 8729 | 439 | 5 | 19454 | 50 |
NTRK1,PTPN6,RPL35,IVNS1ABP,RPL18A |
5.333e-03 | -5.23 | NEIL1 (nei like DNA glycosylase 1) | protein interactions | 79661 | 274 | 4 | 19454 | 50 |
RPS14,RPL37A,RPL8,RPS3A |
5.363e-03 | -5.23 | RHOQ (ras homolog family member Q) | protein interactions | 23433 | 441 | 5 | 19454 | 50 |
ITM2B,DIAPH2,FCHO2,SPECC1,GAB1 |
5.392e-03 | -5.22 | Ribosomal_uS11_CS | interpro domains | IPR018102 | 2 | 1 | 18521 | 50 |
RPS14 |
5.392e-03 | -5.22 | Tyr_Pase_non-rcpt_typ-6/11 | interpro domains | IPR012152 | 2 | 1 | 18521 | 50 |
PTPN6 |
5.392e-03 | -5.22 | Ribosomal_uL11_C_sf | interpro domains | IPR036769 | 2 | 1 | 18521 | 50 |
RPL12 |
5.392e-03 | -5.22 | Ribosomal_uL11 | interpro domains | IPR000911 | 2 | 1 | 18521 | 50 |
RPL12 |
5.392e-03 | -5.22 | Ribosomal_uL2 | interpro domains | IPR002171 | 2 | 1 | 18521 | 50 |
RPL8 |
5.392e-03 | -5.22 | Ribosomal_eL37/eL43 | interpro domains | IPR011331 | 2 | 1 | 18521 | 50 |
RPL37A |
5.392e-03 | -5.22 | Ribosomal_uS11 | interpro domains | IPR001971 | 2 | 1 | 18521 | 50 |
RPS14 |
5.392e-03 | -5.22 | Ribosomal_uL2_C | interpro domains | IPR022669 | 2 | 1 | 18521 | 50 |
RPL8 |
5.392e-03 | -5.22 | Nuc_recep-AF1 | interpro domains | IPR021780 | 2 | 1 | 18521 | 50 |
RXRA |
5.392e-03 | -5.22 | Kinase_SYK/ZAP-70_inter-SH2_sf | interpro domains | IPR023420 | 2 | 1 | 18521 | 50 |
SYK |
5.392e-03 | -5.22 | Ribosomal_uL13_CS | interpro domains | IPR023563 | 2 | 1 | 18521 | 50 |
RPL13A |
5.392e-03 | -5.22 | Ribosomal_uL13_sf | interpro domains | IPR036899 | 2 | 1 | 18521 | 50 |
RPL13A |
5.392e-03 | -5.22 | Saposin_chordata | interpro domains | IPR021165 | 2 | 1 | 18521 | 50 |
PSAP |
5.392e-03 | -5.22 | SYK/ZAP-70_N_SH2 | interpro domains | IPR035838 | 2 | 1 | 18521 | 50 |
SYK |
5.392e-03 | -5.22 | Ribosomal_uL15 | interpro domains | IPR030878 | 2 | 1 | 18521 | 50 |
RPL27A |
5.392e-03 | -5.22 | Ribosomal_uL2_RNA-bd_dom | interpro domains | IPR022666 | 2 | 1 | 18521 | 50 |
RPL8 |
5.392e-03 | -5.22 | Ribosomal_eL44 | interpro domains | IPR000552 | 2 | 1 | 18521 | 50 |
RPL36A |
5.392e-03 | -5.22 | Ribosomal_uL11_C | interpro domains | IPR020783 | 2 | 1 | 18521 | 50 |
RPL12 |
5.392e-03 | -5.22 | Tyr_kinase_non-rcpt_SYK/ZAP70 | interpro domains | IPR012234 | 2 | 1 | 18521 | 50 |
SYK |
5.392e-03 | -5.22 | Neogenin_C | interpro domains | IPR010560 | 2 | 1 | 18521 | 50 |
DCC |
5.392e-03 | -5.22 | Ribosomal_uL13 | interpro domains | IPR005822 | 2 | 1 | 18521 | 50 |
RPL13A |
5.392e-03 | -5.22 | Ribosomal_uL11_N | interpro domains | IPR020784 | 2 | 1 | 18521 | 50 |
RPL12 |
5.392e-03 | -5.22 | Ribosomal_uL11_N_sf | interpro domains | IPR036796 | 2 | 1 | 18521 | 50 |
RPL12 |
5.392e-03 | -5.22 | CAPS | interpro domains | IPR033227 | 2 | 1 | 18521 | 50 |
CADPS2 |
5.402e-03 | -5.22 | MYO18A (myosin XVIIIA) | protein interactions | 399687 | 275 | 4 | 19454 | 50 |
RPS14,BMP2K,SPECC1,CTSS |
5.409e-03 | -5.22 | macrophage colony-stimulating factor receptor activity | molecular function | GO:0005011 | 2 | 1 | 18094 | 49 |
CSF1R |
5.409e-03 | -5.22 | nerve growth factor receptor activity | molecular function | GO:0010465 | 2 | 1 | 18094 | 49 |
NTRK1 |
5.409e-03 | -5.22 | macrophage migration inhibitory factor binding | molecular function | GO:0035718 | 2 | 1 | 18094 | 49 |
CD74 |
5.409e-03 | -5.22 | sodium:sulfate symporter activity | molecular function | GO:0015382 | 2 | 1 | 18094 | 49 |
SLC13A1 |
5.466e-03 | -5.21 | IRF2BPL (interferon regulatory factor 2 binding protein like) | protein interactions | 64207 | 43 | 2 | 19454 | 50 |
NTRK1,HCK |
5.466e-03 | -5.21 | EXOC6B (exocyst complex component 6B) | protein interactions | 23233 | 43 | 2 | 19454 | 50 |
RPS20,NTRK1 |
5.471e-03 | -5.21 | RBBP5 (RB binding protein 5, histone lysine methyltransferase complex subunit) | protein interactions | 5929 | 276 | 4 | 19454 | 50 |
SPECC1,RPL37A,RPS25,RPL13A |
5.471e-03 | -5.21 | SNU13 (small nuclear ribonucleoprotein 13) | protein interactions | 4809 | 276 | 4 | 19454 | 50 |
RPL12,RPL18A,RPL37A,RPS14 |
5.475e-03 | -5.21 | LARP1B (La ribonucleoprotein 1B) | protein interactions | 55132 | 139 | 3 | 19454 | 50 |
RPS3A,RBM47,RPS20 |
5.475e-03 | -5.21 | DUSP22 (dual specificity phosphatase 22) | protein interactions | 56940 | 139 | 3 | 19454 | 50 |
RPL27A,PTPN6,GNAI2 |
5.486e-03 | -5.21 | regulation of interleukin-3 production | biological process | GO:0032672 | 2 | 1 | 18204 | 50 |
SYK |
5.486e-03 | -5.21 | serotonin secretion by platelet | biological process | GO:0002554 | 2 | 1 | 18204 | 50 |
SYK |
5.486e-03 | -5.21 | positive regulation of thyroid hormone mediated signaling pathway | biological process | GO:0002157 | 2 | 1 | 18204 | 50 |
RXRA |
5.486e-03 | -5.21 | regulation of Kit signaling pathway | biological process | GO:1900234 | 2 | 1 | 18204 | 50 |
SH2B3 |
5.486e-03 | -5.21 | negative regulation of Kit signaling pathway | biological process | GO:1900235 | 2 | 1 | 18204 | 50 |
SH2B3 |
5.486e-03 | -5.21 | negative regulation of cytoplasmic translational initiation | biological process | GO:1904689 | 2 | 1 | 18204 | 50 |
RPL13A |
5.486e-03 | -5.21 | positive regulation of macrophage migration inhibitory factor signaling pathway | biological process | GO:2000448 | 2 | 1 | 18204 | 50 |
CD74 |
5.612e-03 | -5.18 | Ribosomal_L11_N | pfam domains | PF03946 | 2 | 1 | 17795 | 50 |
RPL12 |
5.612e-03 | -5.18 | Ribosomal_L13 | pfam domains | PF00572 | 2 | 1 | 17795 | 50 |
RPL13A |
5.612e-03 | -5.18 | Ribosomal_L27A | pfam domains | PF00828 | 2 | 1 | 17795 | 50 |
RPL27A |
5.612e-03 | -5.18 | Neogenin_C | pfam domains | PF06583 | 2 | 1 | 17795 | 50 |
DCC |
5.612e-03 | -5.18 | Ribosomal_L44 | pfam domains | PF00935 | 2 | 1 | 17795 | 50 |
RPL36A |
5.612e-03 | -5.18 | Ribosomal_L2_C | pfam domains | PF03947 | 2 | 1 | 17795 | 50 |
RPL8 |
5.612e-03 | -5.18 | Ribosomal_S11 | pfam domains | PF00411 | 2 | 1 | 17795 | 50 |
RPS14 |
5.612e-03 | -5.18 | Ribosomal_L11 | pfam domains | PF00298 | 2 | 1 | 17795 | 50 |
RPL12 |
5.612e-03 | -5.18 | Nuc_recep-AF1 | pfam domains | PF11825 | 2 | 1 | 17795 | 50 |
RXRA |
5.612e-03 | -5.18 | Ribosomal_L2 | pfam domains | PF00181 | 2 | 1 | 17795 | 50 |
RPL8 |
5.662e-03 | -5.17 | antigen processing and presentation of exogenous peptide antigen | biological process | GO:0002478 | 41 | 2 | 18204 | 50 |
CD74,CTSS |
5.696e-03 | -5.17 | MAPK7 (mitogen-activated protein kinase 7) | protein interactions | 5598 | 141 | 3 | 19454 | 50 |
IVNS1ABP,RXRA,NTRK1 |
5.717e-03 | -5.16 | NKX3-1 (NK3 homeobox 1) | protein interactions | 4824 | 44 | 2 | 19454 | 50 |
RPL37A,HIPK2 |
5.717e-03 | -5.16 | EME1 (essential meiotic structure-specific endonuclease 1) | protein interactions | 146956 | 44 | 2 | 19454 | 50 |
RPL13A,RPL27A |
5.747e-03 | -5.16 | knee | COSMIC cancer mutations | knee | 125 | 3 | 16828 | 49 |
DCC,ADAM28,NTRK1 |
5.747e-03 | -5.16 | immune response-regulating cell surface receptor signaling pathway | biological process | GO:0002768 | 262 | 4 | 18204 | 50 |
HCK,FYB1,PTPN6,SYK |
5.754e-03 | -5.16 | DNAJC25 (DnaJ heat shock protein family (Hsp40) member C25) | protein interactions | 548645 | 280 | 4 | 19454 | 50 |
RPL34,RPL8,RPL14,RPL13A |
5.773e-03 | -5.15 | SH2 domain binding | molecular function | GO:0042169 | 42 | 2 | 18094 | 49 |
PTPN6,SYK |
5.826e-03 | -5.15 | IKZF1 (IKAROS family zinc finger 1) | protein interactions | 10320 | 281 | 4 | 19454 | 50 |
RPL12,RPS14,RPS25,RPL36A |
5.826e-03 | -5.15 | AURKAIP1 (aurora kinase A interacting protein 1) | protein interactions | 54998 | 281 | 4 | 19454 | 50 |
RPS3A,RPL13A,RPL8,RPS14 |
5.832e-03 | -5.14 | SH3 Domains | gene3d domains | 2.30.30.40 | 223 | 4 | 14470 | 47 |
HCK,FYB1,ELMO1,CARD10 |
5.880e-03 | -5.14 | The role of Nef in HIV-1 replication and disease pathogenesis | REACTOME pathways | R-HSA-164952 | 29 | 2 | 10285 | 41 |
HCK,ELMO1 |
5.880e-03 | -5.14 | YAP1- and WWTR1 (TAZ)-stimulated gene expression | REACTOME pathways | R-HSA-2032785 | 29 | 2 | 10285 | 41 |
HIPK2,RXRA |
5.888e-03 | -5.13 | AGO2 (argonaute RISC catalytic component 2) | protein interactions | 27161 | 451 | 5 | 19454 | 50 |
NTRK1,RPL27A,RPS20,RBM47,FCHO2 |
5.922e-03 | -5.13 | NVL (nuclear VCP like) | protein interactions | 4931 | 143 | 3 | 19454 | 50 |
RPS14,RPL14,RPL13A |
5.935e-03 | -5.13 | positive regulation of interleukin-10 production | biological process | GO:0032733 | 42 | 2 | 18204 | 50 |
SYK,RBM47 |
5.950e-03 | -5.12 | signaling receptor binding | molecular function | GO:0005102 | 1493 | 10 | 18094 | 49 |
ITGAX,GNAI2,FYB1,SH2B3,HCK,SYK,NTRK1,CD74,ARAP1,DIAPH2 |
5.973e-03 | -5.12 | SKAP2 (src kinase associated phosphoprotein 2) | protein interactions | 8935 | 45 | 2 | 19454 | 50 |
HCK,FYB1 |
5.978e-03 | -5.12 | PH-like_dom_sf | interpro domains | IPR011993 | 431 | 5 | 18521 | 50 |
CADPS2,GAB1,SH2B3,ELMO1,ARAP1 |
5.998e-03 | -5.12 | cellular response to organic substance | biological process | GO:0071310 | 1716 | 11 | 18204 | 50 |
NTRK1,CSF1R,SH2B3,PTPN6,CTSS,SYK,RPL13A,GAB1,CD74,HCK,RXRA |
6.037e-03 | -5.11 | CCDC86 (coiled-coil domain containing 86) | protein interactions | 79080 | 144 | 3 | 19454 | 50 |
RPS3A,RPS14,RPL8 |
6.037e-03 | -5.11 | Calml3 (calmodulin-like 3) | protein interactions | 70405 | 144 | 3 | 19454 | 50 |
SPECC1,BMP2K,GNAI2 |
6.108e-03 | -5.10 | LCK (LCK proto-oncogene, Src family tyrosine kinase) | protein interactions | 3932 | 455 | 5 | 19454 | 50 |
GAB1,SYK,HCK,PTPN6,SH2B3 |
6.154e-03 | -5.09 | DYNC1LI2 (dynein cytoplasmic 1 light intermediate chain 2) | protein interactions | 1783 | 145 | 3 | 19454 | 50 |
NTRK1,RPS26,RPS20 |
6.164e-03 | -5.09 | GSK3A (glycogen synthase kinase 3 alpha) | protein interactions | 2931 | 456 | 5 | 19454 | 50 |
GAB1,RAPGEF6,RPS3A,RPS20,RPS26 |
6.196e-03 | -5.08 | YTHDF2 (YTH N6-methyladenosine RNA binding protein F2) | protein interactions | 51441 | 286 | 4 | 19454 | 50 |
BMP2K,NTRK1,RBM47,RPS20 |
6.213e-03 | -5.08 | regulation of bone resorption | biological process | GO:0045124 | 43 | 2 | 18204 | 50 |
SYK,CSF1R |
6.234e-03 | -5.08 | ANKRD44 (ankyrin repeat domain 44) | protein interactions | 91526 | 46 | 2 | 19454 | 50 |
NTRK1,ENTPD1 |
6.347e-03 | -5.06 | regulation of multicellular organismal development | biological process | GO:2000026 | 1484 | 10 | 18204 | 50 |
PTPN6,GAB1,SYK,CD74,RXRA,ITGAX,NTRK1,DCC,HIPK2,BMP2K |
6.358e-03 | -5.06 | organic cyclic compound binding | molecular function | GO:0097159 | 6285 | 26 | 18094 | 49 |
RPS14,RXRA,ITM2B,RPL14,RPS3A,RBM47,SYK,HIPK2,RPS25,RPL35,RPL12,CSF1R,HCK,RPS26,RPL34,NTRK1,RPL27A,RPL36A,BMP2K,ENTPD1,RPL18A,RPL13A,RPL8,RPL37A,RPS20,GNAI2 |
6.383e-03 | -5.05 | regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction | biological process | GO:0051896 | 270 | 4 | 18204 | 50 |
NTRK1,PTPN6,SH2B3,CSF1R |
6.391e-03 | -5.05 | IGF1R (insulin like growth factor 1 receptor) | protein interactions | 3480 | 460 | 5 | 19454 | 50 |
FCHO2,GAB1,GNAI2,PTPN6,NTRK1 |
6.486e-03 | -5.04 | - | gene3d domains | 2.20.25.30 | 2 | 1 | 14470 | 47 |
RPL37A |
6.486e-03 | -5.04 | Ribosomal protein L13 | gene3d domains | 3.90.1180.10 | 2 | 1 | 14470 | 47 |
RPL13A |
6.486e-03 | -5.04 | - | gene3d domains | 3.10.450.80 | 2 | 1 | 14470 | 47 |
RPL36A |
6.486e-03 | -5.04 | Ribosomal protein L11, C-terminal domain | gene3d domains | 1.10.10.250 | 2 | 1 | 14470 | 47 |
RPL12 |
6.486e-03 | -5.04 | Ribosomal protein L11/L12, N-terminal domain | gene3d domains | 3.30.1550.10 | 2 | 1 | 14470 | 47 |
RPL12 |
6.498e-03 | -5.04 | leukocyte degranulation | biological process | GO:0043299 | 44 | 2 | 18204 | 50 |
HCK,SYK |
6.498e-03 | -5.04 | B cell receptor signaling pathway | biological process | GO:0050853 | 44 | 2 | 18204 | 50 |
PTPN6,SYK |
6.550e-03 | -5.03 | postsynapse | cellular component | GO:0098794 | 646 | 6 | 19108 | 50 |
RPL8,DCC,RPS14,RPL14,RPS25,RPL12 |
6.562e-03 | -5.03 | immune system process | biological process | GO:0002376 | 1991 | 12 | 18204 | 50 |
NTRK1,FYB1,CSF1R,SYK,RPL13A,CTSS,CD74,SH2B3,RPS14,HIPK2,PTPN6,HCK |
6.571e-03 | -5.03 | antigen receptor-mediated signaling pathway | biological process | GO:0050851 | 139 | 3 | 18204 | 50 |
SYK,FYB1,PTPN6 |
6.571e-03 | -5.03 | regulation of cell shape | biological process | GO:0008360 | 139 | 3 | 18204 | 50 |
HCK,CSF1R,ARAP1 |
6.589e-03 | -5.02 | cell surface receptor signaling pathway | biological process | GO:0007166 | 1992 | 12 | 18204 | 50 |
PTPN6,GNAI2,HCK,HIPK2,SH2B3,SYK,GAB1,CD74,ITGAX,FYB1,NTRK1,CSF1R |
6.604e-03 | -5.02 | non-membrane spanning protein tyrosine kinase activity | molecular function | GO:0004715 | 45 | 2 | 18094 | 49 |
SYK,HCK |
6.660e-03 | -5.01 | EPB41L5 (erythrocyte membrane protein band 4.1 like 5) | protein interactions | 57669 | 292 | 4 | 19454 | 50 |
RPL35,RPL14,NTRK1,RPL13A |
6.702e-03 | -5.01 | myeloid cell homeostasis | biological process | GO:0002262 | 140 | 3 | 18204 | 50 |
RPS14,HIPK2,SH2B3 |
6.728e-03 | -5.00 | positive regulation of phosphorylation | biological process | GO:0042327 | 619 | 6 | 18204 | 50 |
CARD10,SYK,NTRK1,HIPK2,CD74,CSF1R |
6.781e-03 | -4.99 | Ribosomal_L2_C | smart domains | SM01382 | 2 | 1 | 9717 | 33 |
RPL8 |
6.781e-03 | -4.99 | Ribosomal_L2 | smart domains | SM01383 | 2 | 1 | 9717 | 33 |
RPL8 |
6.781e-03 | -4.99 | RL11 | smart domains | SM00649 | 2 | 1 | 9717 | 33 |
RPL12 |
6.788e-03 | -4.99 | regulation of type I interferon-mediated signaling pathway | biological process | GO:0060338 | 45 | 2 | 18204 | 50 |
PTPN6,RBM47 |
6.803e-03 | -4.99 | EIF4A3 (eukaryotic translation initiation factor 4A3) | protein interactions | 9775 | 467 | 5 | 19454 | 50 |
RPL8,RPL37A,RPL27A,NTRK1,RPL13A |
6.829e-03 | -4.99 | myelofibrosis | COSMIC cancer mutations | myelofibrosis | 413 | 5 | 16828 | 49 |
DIAPH2,SH2B3,PDZRN3,CD74,CSF1R |
6.829e-03 | -4.99 | haematopoietic_and_lymphoid_tissue-haematopoietic_neoplasm-myelofibrosis | COSMIC cancer mutations | haematopoietic_and_lymphoid_tissue-haematopoietic_neoplasm-myelofibrosis | 413 | 5 | 16828 | 49 |
PDZRN3,SH2B3,CD74,CSF1R,DIAPH2 |
6.881e-03 | -4.98 | RRP15 (ribosomal RNA processing 15 homolog) | protein interactions | 51018 | 151 | 3 | 19454 | 50 |
PTPN6,RPL14,SYK |
6.939e-03 | -4.97 | haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-follicular_lymphoma | COSMIC cancer mutations | haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-follicular_lymphoma | 981 | 8 | 16828 | 49 |
DIAPH2,ITGAX,GNAI2,HCK,CTSS,ENTPD1,NTRK1,RXRA |
6.994e-03 | -4.96 | intracellular signal transduction | biological process | GO:0035556 | 1505 | 10 | 18204 | 50 |
RAPGEF6,HIPK2,SH2B3,IVNS1ABP,CARD10,ELMO1,HCK,PTPN6,RGL1,SYK |
7.007e-03 | -4.96 | MAP3K1 (mitogen-activated protein kinase kinase kinase 1) | protein interactions | 4214 | 152 | 3 | 19454 | 50 |
CD74,NTRK1,HIPK2 |
7.007e-03 | -4.96 | UTP3 (UTP3 small subunit processome component) | protein interactions | 57050 | 152 | 3 | 19454 | 50 |
RPL8,RPL37A,RPL14 |
7.049e-03 | -4.95 | TNFAIP8L1 (TNF alpha induced protein 8 like 1) | protein interactions | 126282 | 49 | 2 | 19454 | 50 |
RPL12,RPS3A |
7.109e-03 | -4.95 | SRPK1 (SRSF protein kinase 1) | protein interactions | 6732 | 472 | 5 | 19454 | 50 |
SYK,RPS14,PTPN6,RPL13A,NTRK1 |
7.135e-03 | -4.94 | UPF2 (UPF2 regulator of nonsense mediated mRNA decay) | protein interactions | 26019 | 153 | 3 | 19454 | 50 |
RPL8,RPS25,NTRK1 |
7.170e-03 | -4.94 | PROTEIN_KINASE_DOM | prosite domains | PS50011 | 480 | 6 | 12186 | 44 |
SYK,HIPK2,BMP2K,HCK,CSF1R,NTRK1 |
7.203e-03 | -4.93 | RHOF (ras homolog family member F, filopodia associated) | protein interactions | 54509 | 671 | 6 | 19454 | 50 |
RPL13A,DIAPH2,FCHO2,RPL37A,SPECC1,GAB1 |
7.209e-03 | -4.93 | RIBOSOMAL_S11 | prosite domains | PS00054 | 2 | 1 | 12186 | 44 |
RPS14 |
7.209e-03 | -4.93 | RIBOSOMAL_L13 | prosite domains | PS00783 | 2 | 1 | 12186 | 44 |
RPL13A |
7.209e-03 | -4.93 | RIBOSOMAL_L44E | prosite domains | PS01172 | 2 | 1 | 12186 | 44 |
RPL36A |
7.242e-03 | -4.93 | regulated exocytosis | biological process | GO:0045055 | 144 | 3 | 18204 | 50 |
SYK,CADPS2,HCK |
7.263e-03 | -4.92 | MRPL30 (mitochondrial ribosomal protein L30) | protein interactions | 51263 | 154 | 3 | 19454 | 50 |
RPL13A,RPL27A,RPL35 |
7.290e-03 | -4.92 | mRNA binding | molecular function | GO:0003729 | 639 | 6 | 18094 | 49 |
RPL13A,RPS26,RPL35,RPS14,RPS3A,RBM47 |
7.303e-03 | -4.92 | positive regulation of intracellular signal transduction | biological process | GO:1902533 | 1048 | 8 | 18204 | 50 |
PTPN6,SYK,GNAI2,CD74,RPS20,NTRK1,HIPK2,CSF1R |
7.309e-03 | -4.92 | haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-angioimmunoblastic_T_cell_lymphoma | COSMIC cancer mutations | haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-angioimmunoblastic_T_cell_lymphoma | 265 | 4 | 16828 | 49 |
SH2B3,HCK,CTSS,SYK |
7.330e-03 | -4.92 | DOK1 (docking protein 1) | protein interactions | 1796 | 50 | 2 | 19454 | 50 |
HCK,PTPN6 |
7.330e-03 | -4.92 | TRIM15 (tripartite motif containing 15) | protein interactions | 89870 | 50 | 2 | 19454 | 50 |
GAB1,SYK |
7.386e-03 | -4.91 | T cell selection | biological process | GO:0045058 | 47 | 2 | 18204 | 50 |
CD74,SYK |
7.394e-03 | -4.91 | ZBTB24 (zinc finger and BTB domain containing 24) | protein interactions | 9841 | 155 | 3 | 19454 | 50 |
RPL8,RPL14,RPS14 |
7.399e-03 | -4.91 | IKZF3 (IKAROS family zinc finger 3) | protein interactions | 22806 | 301 | 4 | 19454 | 50 |
RPS25,RPL36A,RPL12,RPS14 |
7.400e-03 | -4.91 | skin-face-malignant_melanoma | COSMIC cancer mutations | skin-face-malignant_melanoma | 137 | 3 | 16828 | 49 |
ADAM28,NTRK1,DCC |
7.401e-03 | -4.91 | response to cytokine | biological process | GO:0034097 | 834 | 7 | 18204 | 50 |
HCK,SH2B3,CD74,CSF1R,RPL13A,SYK,PTPN6 |
7.423e-03 | -4.90 | IGF2BP1 (insulin like growth factor 2 mRNA binding protein 1) | protein interactions | 10642 | 477 | 5 | 19454 | 50 |
IVNS1ABP,RPL37A,RPL27A,RBM47,RPS20 |
7.521e-03 | -4.89 | innate immune response-activating signaling pathway | biological process | GO:0002758 | 146 | 3 | 18204 | 50 |
SYK,CTSS,HCK |
7.525e-03 | -4.89 | MRPL52 (mitochondrial ribosomal protein L52) | protein interactions | 122704 | 156 | 3 | 19454 | 50 |
RPL35,RPL13A,RPS3A |
7.525e-03 | -4.89 | NOL10 (nucleolar protein 10) | protein interactions | 79954 | 156 | 3 | 19454 | 50 |
RPS3A,RPL13A,RPL35 |
7.542e-03 | -4.89 | intracellular signaling cassette | biological process | GO:0141124 | 837 | 7 | 18204 | 50 |
ELMO1,SYK,RGL1,PTPN6,RAPGEF6,HIPK2,CARD10 |
7.600e-03 | -4.88 | regulation of innate immune response | biological process | GO:0045088 | 449 | 5 | 18204 | 50 |
RBM47,HCK,SYK,PTPN6,CTSS |
7.617e-03 | -4.88 | SH2D2A (SH2 domain containing 2A) | protein interactions | 9047 | 51 | 2 | 19454 | 50 |
SYK,GAB1 |
7.617e-03 | -4.88 | CD247 (CD247 molecule) | protein interactions | 919 | 51 | 2 | 19454 | 50 |
PTPN6,SH2B3 |
7.617e-03 | -4.88 | FCGR1A (Fc gamma receptor Ia) | protein interactions | 2209 | 51 | 2 | 19454 | 50 |
SYK,HCK |
7.648e-03 | -4.87 | enzyme regulator activity | molecular function | GO:0030234 | 1305 | 9 | 18094 | 49 |
CTSS,PDE6D,RGL1,BMP2K,ELMO1,RAPGEF6,ARAP1,RPS20,PSAP |
7.658e-03 | -4.87 | USP4 (ubiquitin specific peptidase 4) | protein interactions | 7375 | 157 | 3 | 19454 | 50 |
ELMO1,PSAP,NTRK1 |
7.691e-03 | -4.87 | Grip1 (glutamate receptor interacting protein 1) | protein interactions | 74053 | 3 | 1 | 19454 | 50 |
RXRA |
7.691e-03 | -4.87 | SIGLEC11 (sialic acid binding Ig like lectin 11) | protein interactions | 114132 | 3 | 1 | 19454 | 50 |
PTPN6 |
7.691e-03 | -4.87 | WDFY4 (WDFY family member 4) | protein interactions | 57705 | 3 | 1 | 19454 | 50 |
NTRK1 |
7.691e-03 | -4.87 | Pml (promyelocytic leukemia) | protein interactions | 18854 | 3 | 1 | 19454 | 50 |
HIPK2 |
7.691e-03 | -4.87 | Nherf1 (NHERF family PDZ scaffold protein 1) | protein interactions | 26941 | 3 | 1 | 19454 | 50 |
SLC13A1 |
7.691e-03 | -4.87 | SPATA31E1 (SPATA31 subfamily E member 1) | protein interactions | 286234 | 3 | 1 | 19454 | 50 |
RPL14 |
7.691e-03 | -4.87 | Cbl (Casitas B-lineage lymphoma) | protein interactions | 12402 | 3 | 1 | 19454 | 50 |
SYK |
7.691e-03 | -4.87 | LRRN3 (leucine rich repeat neuronal 3) | protein interactions | 54674 | 3 | 1 | 19454 | 50 |
NTRK1 |
7.694e-03 | -4.87 | icosanoid biosynthetic process | biological process | GO:0046456 | 48 | 2 | 18204 | 50 |
SYK,CD74 |
7.694e-03 | -4.87 | regulation of inflammatory response to antigenic stimulus | biological process | GO:0002861 | 48 | 2 | 18204 | 50 |
HCK,SYK |
7.700e-03 | -4.87 | skin-lower_leg-malignant_melanoma | COSMIC cancer mutations | skin-lower_leg-malignant_melanoma | 139 | 3 | 16828 | 49 |
ADAM28,NTRK1,DCC |
7.744e-03 | -4.86 | MYH10 (myosin heavy chain 10) | protein interactions | 4628 | 305 | 4 | 19454 | 50 |
NTRK1,RPS3A,SPECC1,GNAI2 |
7.782e-03 | -4.86 | signal transduction | biological process | GO:0007165 | 4637 | 21 | 18204 | 50 |
ITGAX,ELMO1,RXRA,CD74,SYK,GAB1,CTSS,IVNS1ABP,CSF1R,ARAP1,NTRK1,CARD10,FYB1,HCK,PSAP,GNAI2,PTPN6,RGL1,SH2B3,RAPGEF6,HIPK2 |
7.792e-03 | -4.85 | SKI (SKI proto-oncogene) | protein interactions | 6497 | 158 | 3 | 19454 | 50 |
RPL14,HIPK2,RPL12 |
7.792e-03 | -4.85 | APOE (apolipoprotein E) | protein interactions | 348 | 158 | 3 | 19454 | 50 |
RPL8,RPS14,RPS26 |
7.928e-03 | -4.84 | CEP57 (centrosomal protein 57) | protein interactions | 9702 | 159 | 3 | 19454 | 50 |
RPS3A,RPS25,RPS14 |
7.957e-03 | -4.83 | TRKA activation by NGF | REACTOME pathways | R-HSA-187042 | 2 | 1 | 10285 | 41 |
NTRK1 |
7.983e-03 | -4.83 | positive regulation of innate immune response | biological process | GO:0045089 | 288 | 4 | 18204 | 50 |
SYK,CTSS,RBM47,HCK |
8.007e-03 | -4.83 | platelet aggregation | biological process | GO:0070527 | 49 | 2 | 18204 | 50 |
PTPN6,ENTPD1 |
8.007e-03 | -4.83 | regulation of cell adhesion mediated by integrin | biological process | GO:0033628 | 49 | 2 | 18204 | 50 |
PTPN6,SYK |
8.007e-03 | -4.83 | lung morphogenesis | biological process | GO:0060425 | 49 | 2 | 18204 | 50 |
RPL13A,HIPK2 |
8.078e-03 | -4.82 | Saposin | interpro domains | IPR008373 | 3 | 1 | 18521 | 50 |
PSAP |
8.078e-03 | -4.82 | Muniscin_C | interpro domains | IPR018808 | 3 | 1 | 18521 | 50 |
FCHO2 |
8.078e-03 | -4.82 | PDED_dom | interpro domains | IPR008015 | 3 | 1 | 18521 | 50 |
PDE6D |
8.078e-03 | -4.82 | FYB1/2-like | interpro domains | IPR043443 | 3 | 1 | 18521 | 50 |
FYB1 |
8.078e-03 | -4.82 | SAP_A | interpro domains | IPR003119 | 3 | 1 | 18521 | 50 |
PSAP |
8.078e-03 | -4.82 | Ribosomal_uS10_dom | interpro domains | IPR027486 | 3 | 1 | 18521 | 50 |
RPS20 |
8.078e-03 | -4.82 | NTRK_LRRCT | interpro domains | IPR031635 | 3 | 1 | 18521 | 50 |
NTRK1 |
8.078e-03 | -4.82 | RhoGAP_ARAP | interpro domains | IPR037858 | 3 | 1 | 18521 | 50 |
ARAP1 |
8.078e-03 | -4.82 | PDED_dom_sf | interpro domains | IPR037036 | 3 | 1 | 18521 | 50 |
PDE6D |
8.078e-03 | -4.82 | Na/sul_symport_CS | interpro domains | IPR031312 | 3 | 1 | 18521 | 50 |
SLC13A1 |
8.078e-03 | -4.82 | Ribosomal_uL15/eL18 | interpro domains | IPR021131 | 3 | 1 | 18521 | 50 |
RPL27A |
8.078e-03 | -4.82 | Ribosomal_uS10_dom_sf | interpro domains | IPR036838 | 3 | 1 | 18521 | 50 |
RPS20 |
8.078e-03 | -4.82 | Phe_ZIP_sf | interpro domains | IPR036290 | 3 | 1 | 18521 | 50 |
SH2B3 |
8.078e-03 | -4.82 | ITGAX-like_Ig_3 | interpro domains | IPR048633 | 3 | 1 | 18521 | 50 |
ITGAX |
8.078e-03 | -4.82 | Ribosomal_uL15/eL18_sf | interpro domains | IPR036227 | 3 | 1 | 18521 | 50 |
RPL27A |
8.078e-03 | -4.82 | Ribosomal_uS11_sf | interpro domains | IPR036967 | 3 | 1 | 18521 | 50 |
RPS14 |
8.078e-03 | -4.82 | ELMO_ARM | interpro domains | IPR024574 | 3 | 1 | 18521 | 50 |
ELMO1 |
8.078e-03 | -4.82 | Phe_ZIP | interpro domains | IPR015012 | 3 | 1 | 18521 | 50 |
SH2B3 |
8.078e-03 | -4.82 | SH2B | interpro domains | IPR030523 | 3 | 1 | 18521 | 50 |
SH2B3 |
8.078e-03 | -4.82 | DIA_GBD_sf | interpro domains | IPR044933 | 3 | 1 | 18521 | 50 |
DIAPH2 |
8.078e-03 | -4.82 | ITM2 | interpro domains | IPR040145 | 3 | 1 | 18521 | 50 |
ITM2B |
8.078e-03 | -4.82 | hSH3 | interpro domains | IPR029294 | 3 | 1 | 18521 | 50 |
FYB1 |
8.078e-03 | -4.82 | NTRK | interpro domains | IPR020777 | 3 | 1 | 18521 | 50 |
NTRK1 |
8.078e-03 | -4.82 | SapB_1 | interpro domains | IPR007856 | 3 | 1 | 18521 | 50 |
PSAP |
8.085e-03 | -4.82 | signaling | biological process | GO:0023052 | 4968 | 22 | 18204 | 50 |
ITGAX,SYK,GAB1,FYB1,CARD10,NTRK1,HCK,CADPS2,RGL1,PSAP,GNAI2,HIPK2,CD74,ELMO1,RXRA,CTSS,ARAP1,CSF1R,IVNS1ABP,PTPN6,RAPGEF6,SH2B3 |
8.097e-03 | -4.82 | ribonucleoprotein complex biogenesis | biological process | GO:0022613 | 456 | 5 | 18204 | 50 |
RPS3A,RPS14,RPL35,RPS25,RPL14 |
8.103e-03 | -4.82 | ganglioside GT1b binding | molecular function | GO:1905576 | 3 | 1 | 18094 | 49 |
PSAP |
8.103e-03 | -4.82 | DNA binding domain binding | molecular function | GO:0050692 | 3 | 1 | 18094 | 49 |
RXRA |
8.103e-03 | -4.82 | ganglioside GM1 binding | molecular function | GO:1905573 | 3 | 1 | 18094 | 49 |
PSAP |
8.103e-03 | -4.82 | apyrase activity | molecular function | GO:0004050 | 3 | 1 | 18094 | 49 |
ENTPD1 |
8.103e-03 | -4.82 | vitamin D response element binding | molecular function | GO:0070644 | 3 | 1 | 18094 | 49 |
RXRA |
8.206e-03 | -4.80 | USP40 (ubiquitin specific peptidase 40) | protein interactions | 55230 | 53 | 2 | 19454 | 50 |
RPS20,RPS3A |
8.206e-03 | -4.80 | CLEC7A (C-type lectin domain containing 7A) | protein interactions | 64581 | 53 | 2 | 19454 | 50 |
CD74,SYK |
8.206e-03 | -4.80 | FCGR2A (Fc gamma receptor IIa) | protein interactions | 2212 | 53 | 2 | 19454 | 50 |
HCK,SYK |
8.206e-03 | -4.80 | ZNF92 (zinc finger protein 92) | protein interactions | 168374 | 53 | 2 | 19454 | 50 |
RPL27A,RPL13A |
8.218e-03 | -4.80 | serotonin production involved in inflammatory response | biological process | GO:0002351 | 3 | 1 | 18204 | 50 |
SYK |
8.218e-03 | -4.80 | behavioral response to formalin induced pain | biological process | GO:0061368 | 3 | 1 | 18204 | 50 |
NTRK1 |
8.218e-03 | -4.80 | behavioral response to chemical pain | biological process | GO:0061366 | 3 | 1 | 18204 | 50 |
NTRK1 |
8.218e-03 | -4.80 | lens induction in camera-type eye | biological process | GO:0060235 | 3 | 1 | 18204 | 50 |
HIPK2 |
8.218e-03 | -4.80 | serotonin secretion | biological process | GO:0001820 | 3 | 1 | 18204 | 50 |
SYK |
8.218e-03 | -4.80 | beta selection | biological process | GO:0043366 | 3 | 1 | 18204 | 50 |
SYK |
8.218e-03 | -4.80 | leukocyte migration involved in immune response | biological process | GO:0002522 | 3 | 1 | 18204 | 50 |
HCK |
8.218e-03 | -4.80 | serotonin secretion involved in inflammatory response | biological process | GO:0002442 | 3 | 1 | 18204 | 50 |
SYK |
8.218e-03 | -4.80 | monocyte homeostasis | biological process | GO:0035702 | 3 | 1 | 18204 | 50 |
SH2B3 |
8.218e-03 | -4.80 | dorsal/ventral axon guidance | biological process | GO:0033563 | 3 | 1 | 18204 | 50 |
DCC |
8.218e-03 | -4.80 | basement membrane disassembly | biological process | GO:0034769 | 3 | 1 | 18204 | 50 |
CTSS |
8.218e-03 | -4.80 | spinal cord ventral commissure morphogenesis | biological process | GO:0021965 | 3 | 1 | 18204 | 50 |
DCC |
8.218e-03 | -4.80 | regulation of macrophage migration inhibitory factor signaling pathway | biological process | GO:2000446 | 3 | 1 | 18204 | 50 |
CD74 |
8.327e-03 | -4.79 | antigen processing and presentation of exogenous antigen | biological process | GO:0019884 | 50 | 2 | 18204 | 50 |
CTSS,CD74 |
8.343e-03 | -4.79 | UBAP2 (ubiquitin associated protein 2) | protein interactions | 55833 | 162 | 3 | 19454 | 50 |
NTRK1,RBM47,RPS20 |
8.357e-03 | -4.78 | POLR2A (RNA polymerase II subunit A) | protein interactions | 5430 | 491 | 5 | 19454 | 50 |
NTRK1,RXRA,RPS20,PTPN6,IVNS1ABP |
8.373e-03 | -4.78 | ACTN1 (actinin alpha 1) | protein interactions | 87 | 312 | 4 | 19454 | 50 |
RPS14,CTSS,PTPN6,NTRK1 |
8.406e-03 | -4.78 | SapA | pfam domains | PF02199 | 3 | 1 | 17795 | 50 |
PSAP |
8.406e-03 | -4.78 | ITGAX-like_Ig_3 | pfam domains | PF21520 | 3 | 1 | 17795 | 50 |
ITGAX |
8.406e-03 | -4.78 | SapB_1 | pfam domains | PF05184 | 3 | 1 | 17795 | 50 |
PSAP |
8.406e-03 | -4.78 | ELMO_ARM | pfam domains | PF11841 | 3 | 1 | 17795 | 50 |
ELMO1 |
8.406e-03 | -4.78 | Phe_ZIP | pfam domains | PF08916 | 3 | 1 | 17795 | 50 |
SH2B3 |
8.406e-03 | -4.78 | hSH3 | pfam domains | PF14603 | 3 | 1 | 17795 | 50 |
FYB1 |
8.406e-03 | -4.78 | LRRCT_2 | pfam domains | PF16920 | 3 | 1 | 17795 | 50 |
NTRK1 |
8.406e-03 | -4.78 | muHD | pfam domains | PF10291 | 3 | 1 | 17795 | 50 |
FCHO2 |
8.406e-03 | -4.78 | GMP_PDE_delta | pfam domains | PF05351 | 3 | 1 | 17795 | 50 |
PDE6D |
8.406e-03 | -4.78 | Ribosomal_S10 | pfam domains | PF00338 | 3 | 1 | 17795 | 50 |
RPS20 |
8.417e-03 | -4.78 | signaling receptor complex adaptor activity | molecular function | GO:0030159 | 51 | 2 | 18094 | 49 |
CARD10,SH2B3 |
8.484e-03 | -4.77 | DNAJB12 (DnaJ heat shock protein family (Hsp40) member B12) | protein interactions | 54788 | 163 | 3 | 19454 | 50 |
CD74,CTSS,NTRK1 |
8.484e-03 | -4.77 | SLX9 (SLX9 ribosome biogenesis factor) | protein interactions | 85395 | 163 | 3 | 19454 | 50 |
RPS14,RPS3A,RPS25 |
8.484e-03 | -4.77 | MKRN1 (makorin ring finger protein 1) | protein interactions | 23608 | 163 | 3 | 19454 | 50 |
RPS26,SLC13A1,RPL35 |
8.507e-03 | -4.77 | MEX3A (mex-3 RNA binding family member A) | protein interactions | 92312 | 54 | 2 | 19454 | 50 |
RBM47,NTRK1 |
8.567e-03 | -4.76 | NEDD4 (NEDD4 E3 ubiquitin protein ligase) | protein interactions | 4734 | 494 | 5 | 19454 | 50 |
NTRK1,RPS3A,RPL18A,RAPGEF6,SYK |
8.651e-03 | -4.75 | regulation of bone remodeling | biological process | GO:0046850 | 51 | 2 | 18204 | 50 |
CSF1R,SYK |
8.651e-03 | -4.75 | regulation of granulocyte chemotaxis | biological process | GO:0071622 | 51 | 2 | 18204 | 50 |
CSF1R,CD74 |
8.758e-03 | -4.74 | EGF receptor (ErbB1) signaling pathway | Pathway Interaction DB | erbb1_receptor_proximal_pathway | 25 | 2 | 2226 | 13 |
PTPN6,GAB1 |
8.771e-03 | -4.74 | SENP2 (SUMO specific peptidase 2) | protein interactions | 59343 | 165 | 3 | 19454 | 50 |
HIPK2,ADAM28,RPS25 |
8.771e-03 | -4.74 | SBDS (SBDS ribosome maturation factor) | protein interactions | 51119 | 165 | 3 | 19454 | 50 |
RPL12,RPL8,RPL14 |
8.772e-03 | -4.74 | stomach-carcinoma | COSMIC cancer mutations | stomach-carcinoma | 439 | 5 | 16828 | 49 |
HCK,CSF1R,HIPK2,BMP2K,SYK |
8.901e-03 | -4.72 | PML (PML nuclear body scaffold) | protein interactions | 5371 | 923 | 7 | 19454 | 50 |
RPL13A,RXRA,NTRK1,HIPK2,RPL18A,RPL8,RPL14 |
8.903e-03 | -4.72 | late endosome | cellular component | GO:0005770 | 312 | 4 | 19108 | 50 |
NTRK1,PSAP,CTSS,CD74 |
8.917e-03 | -4.72 | WDR46 (WD repeat domain 46) | protein interactions | 9277 | 166 | 3 | 19454 | 50 |
RPS3A,RPL37A,RPL35 |
8.917e-03 | -4.72 | CPD (carboxypeptidase D) | protein interactions | 1362 | 166 | 3 | 19454 | 50 |
CTSS,NTRK1,CSF1R |
8.917e-03 | -4.72 | SLK (STE20 like kinase) | protein interactions | 9748 | 166 | 3 | 19454 | 50 |
PSAP,NTRK1,SPECC1 |
8.917e-03 | -4.72 | MED12 (mediator complex subunit 12) | protein interactions | 9968 | 166 | 3 | 19454 | 50 |
RPL12,RPS3A,NTRK1 |
8.939e-03 | -4.72 | EIF4A1 (eukaryotic translation initiation factor 4A1) | protein interactions | 1973 | 318 | 4 | 19454 | 50 |
RPL8,NTRK1,CD74,RPS26 |
8.972e-03 | -4.71 | chest | COSMIC cancer mutations | chest | 147 | 3 | 16828 | 49 |
DCC,NTRK1,CSF1R |
8.978e-03 | -4.71 | cell communication | biological process | GO:0007154 | 5010 | 22 | 18204 | 50 |
HCK,PSAP,GNAI2,RGL1,CADPS2,PTPN6,SH2B3,HIPK2,RAPGEF6,ITGAX,ELMO1,RXRA,CD74,SYK,GAB1,CTSS,IVNS1ABP,CSF1R,ARAP1,NTRK1,CARD10,FYB1 |
8.982e-03 | -4.71 | membrane invagination | biological process | GO:0010324 | 52 | 2 | 18204 | 50 |
FCHO2,ELMO1 |
9.013e-03 | -4.71 | protein autophosphorylation | biological process | GO:0046777 | 156 | 3 | 18204 | 50 |
HCK,CSF1R,NTRK1 |
9.057e-03 | -4.70 | tertiary granule | cellular component | GO:0070820 | 164 | 3 | 19108 | 50 |
CTSS,ITGAX,PTPN6 |
9.063e-03 | -4.70 | TP73 (tumor protein p73) | protein interactions | 7161 | 167 | 3 | 19454 | 50 |
HCK,HIPK2,RPS14 |
9.063e-03 | -4.70 | USP48 (ubiquitin specific peptidase 48) | protein interactions | 84196 | 167 | 3 | 19454 | 50 |
NTRK1,RPL27A,PSAP |
9.122e-03 | -4.70 | tertiary granule lumen | cellular component | GO:1904724 | 55 | 2 | 19108 | 50 |
CTSS,PTPN6 |
9.125e-03 | -4.70 | OTX2 (orthodenticle homeobox 2) | protein interactions | 5015 | 56 | 2 | 19454 | 50 |
RPS26,RBM47 |
9.125e-03 | -4.70 | PIK3CG (phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma) | protein interactions | 5294 | 56 | 2 | 19454 | 50 |
GAB1,SYK |
9.212e-03 | -4.69 | RALBP1 (ralA binding protein 1) | protein interactions | 10928 | 168 | 3 | 19454 | 50 |
RBM47,HCK,BMP2K |
9.212e-03 | -4.69 | POU2F1 (POU class 2 homeobox 1) | protein interactions | 5451 | 168 | 3 | 19454 | 50 |
RPS14,RPL37A,RXRA |
9.212e-03 | -4.69 | EIF4G2 (eukaryotic translation initiation factor 4 gamma 2) | protein interactions | 1982 | 168 | 3 | 19454 | 50 |
RPS20,CD74,NTRK1 |
9.295e-03 | -4.68 | MAPRE1 (microtubule associated protein RP/EB family member 1) | protein interactions | 22919 | 504 | 5 | 19454 | 50 |
NTRK1,RPS25,RPL35,GNAI2,SPECC1 |
9.308e-03 | -4.68 | chronic_myelomonocytic_leukaemia | COSMIC cancer mutations | chronic_myelomonocytic_leukaemia | 149 | 3 | 16828 | 49 |
SH2B3,CSF1R,HIPK2 |
9.308e-03 | -4.68 | haematopoietic_and_lymphoid_tissue-haematopoietic_neoplasm-chronic_myelomonocytic_leukaemia | COSMIC cancer mutations | haematopoietic_and_lymphoid_tissue-haematopoietic_neoplasm-chronic_myelomonocytic_leukaemia | 149 | 3 | 16828 | 49 |
HIPK2,CSF1R,SH2B3 |
9.318e-03 | -4.68 | regulation of platelet activation | biological process | GO:0010543 | 53 | 2 | 18204 | 50 |
SYK,SH2B3 |
9.329e-03 | -4.67 | COP1 (COP1 E3 ubiquitin ligase) | protein interactions | 64326 | 322 | 4 | 19454 | 50 |
RPL27A,RPL18A,RPL35,RPS14 |
9.361e-03 | -4.67 | MRPL40 (mitochondrial ribosomal protein L40) | protein interactions | 64976 | 169 | 3 | 19454 | 50 |
RPL13A,RPL27A,RPL35 |
9.385e-03 | -4.67 | YBX1 (Y-box binding protein 1) | protein interactions | 4904 | 710 | 6 | 19454 | 50 |
NTRK1,RPS20,RPL35,RPS3A,RPL13A,IVNS1ABP |
9.395e-03 | -4.67 | positive regulation of kinase activity | biological process | GO:0033674 | 302 | 4 | 18204 | 50 |
CSF1R,CD74,CARD10,NTRK1 |
9.442e-03 | -4.66 | ZNF771 (zinc finger protein 771) | protein interactions | 51333 | 57 | 2 | 19454 | 50 |
RPL14,RPL13A |
9.442e-03 | -4.66 | PRDM5 (PR/SET domain 5) | protein interactions | 11107 | 57 | 2 | 19454 | 50 |
RPL18A,RPL8 |
9.492e-03 | -4.66 | phagocytosis | biological process | GO:0006909 | 159 | 3 | 18204 | 50 |
ELMO1,HCK,SYK |
9.513e-03 | -4.66 | ZEB1 (zinc finger E-box binding homeobox 1) | protein interactions | 6935 | 170 | 3 | 19454 | 50 |
RPS3A,RPS14,RPL14 |
9.530e-03 | -4.65 | human chrXq21.33 | chromosome location | human chrXq21.33 | 5 | 1 | 26134 | 50 |
DIAPH2 |
9.665e-03 | -4.64 | TLX1 (T cell leukemia homeobox 1) | protein interactions | 3195 | 171 | 3 | 19454 | 50 |
RPL35,RPL36A,RPS3A |
9.695e-03 | -4.64 | regulation of intracellular signal transduction | biological process | GO:1902531 | 1832 | 11 | 18204 | 50 |
RPS20,HIPK2,SH2B3,PTPN6,GNAI2,NTRK1,ARAP1,CSF1R,IVNS1ABP,SYK,CD74 |
9.713e-03 | -4.63 | Formin, diaphanous GTPase-binding domain | gene3d domains | 1.10.20.40 | 3 | 1 | 14470 | 47 |
DIAPH2 |
9.713e-03 | -4.63 | - | gene3d domains | 6.10.140.110 | 3 | 1 | 14470 | 47 |
SH2B3 |
9.713e-03 | -4.63 | Ribosomal protein S11 | gene3d domains | 3.30.420.80 | 3 | 1 | 14470 | 47 |
RPS14 |
9.713e-03 | -4.63 | Ribosomal protein S10 domain | gene3d domains | 3.30.70.600 | 3 | 1 | 14470 | 47 |
RPS20 |
9.713e-03 | -4.63 | - | gene3d domains | 1.20.58.630 | 3 | 1 | 14470 | 47 |
DIAPH2 |
9.713e-03 | -4.63 | - | gene3d domains | 6.10.250.810 | 3 | 1 | 14470 | 47 |
ELMO1 |
9.713e-03 | -4.63 | - | gene3d domains | 3.100.10.10 | 3 | 1 | 14470 | 47 |
RPL27A |
9.713e-03 | -4.63 | GMP phosphodiesterase, delta subunit | gene3d domains | 2.70.50.40 | 3 | 1 | 14470 | 47 |
PDE6D |
9.713e-03 | -4.63 | - | gene3d domains | 6.10.30.30 | 3 | 1 | 14470 | 47 |
DIAPH2 |
9.751e-03 | -4.63 | GRSF1 (G-rich RNA sequence binding factor 1) | protein interactions | 2926 | 510 | 5 | 19454 | 50 |
RPL14,SYK,RPL12,RPL18A,RPL13A |
9.763e-03 | -4.63 | RIOX1 (ribosomal oxygenase 1) | protein interactions | 79697 | 58 | 2 | 19454 | 50 |
RPL8,RPL14 |
9.763e-03 | -4.63 | RBAK (RB associated KRAB zinc finger) | protein interactions | 57786 | 58 | 2 | 19454 | 50 |
RPL27A,RPL13A |
9.819e-03 | -4.62 | RAB11FIP5 (RAB11 family interacting protein 5) | protein interactions | 26056 | 172 | 3 | 19454 | 50 |
RPL34,NTRK1,PSAP |
9.819e-03 | -4.62 | PPP4R3A (protein phosphatase 4 regulatory subunit 3A) | protein interactions | 55671 | 172 | 3 | 19454 | 50 |
NTRK1,SYK,RPL18A |
9.819e-03 | -4.62 | MRPL20 (mitochondrial ribosomal protein L20) | protein interactions | 55052 | 172 | 3 | 19454 | 50 |
RPL35,RPL13A,RPL27A |
9.819e-03 | -4.62 | positive regulation of peptidyl-tyrosine phosphorylation | biological process | GO:0050731 | 161 | 3 | 18204 | 50 |
CSF1R,CD74,SYK |
9.975e-03 | -4.61 | NOC4L (nucleolar complex associated 4 homolog) | protein interactions | 79050 | 173 | 3 | 19454 | 50 |
RPL35,RPS14,RPS3A |
9.975e-03 | -4.61 | MALSU1 (mitochondrial assembly of ribosomal large subunit 1) | protein interactions | 115416 | 173 | 3 | 19454 | 50 |
RBM47,RPL13A,RPL27A |
9.985e-03 | -4.61 | FOXA1 (forkhead box A1) | protein interactions | 3169 | 513 | 5 | 19454 | 50 |
RPL14,RPL8,RPL34,RPL36A,RPL13A |
1.001e-02 | -4.60 | Fc receptor signaling pathway | biological process | GO:0038093 | 55 | 2 | 18204 | 50 |
SYK,HCK |
1.013e-02 | -4.59 | ERP44 (endoplasmic reticulum protein 44) | protein interactions | 23071 | 174 | 3 | 19454 | 50 |
BMP2K,NTRK1,CTSS |
1.015e-02 | -4.59 | SAPA | smart domains | SM00162 | 3 | 1 | 9717 | 33 |
PSAP |
1.015e-02 | -4.59 | Ribosomal_S10 | smart domains | SM01403 | 3 | 1 | 9717 | 33 |
RPS20 |
1.016e-02 | -4.59 | phosphotransferase activity, alcohol group as acceptor | molecular function | GO:0016773 | 686 | 6 | 18094 | 49 |
HIPK2,SYK,CSF1R,BMP2K,NTRK1,HCK |
1.024e-02 | -4.58 | FAM47B (family with sequence similarity 47 member B) | protein interactions | 170062 | 4 | 1 | 19454 | 50 |
CARD10 |
1.024e-02 | -4.58 | PLEKHD1 (pleckstrin homology and coiled-coil domain containing D1) | protein interactions | 400224 | 4 | 1 | 19454 | 50 |
SYK |
1.024e-02 | -4.58 | MRGPRX1 (MAS related GPR family member X1) | protein interactions | 259249 | 4 | 1 | 19454 | 50 |
GNAI2 |
1.024e-02 | -4.58 | H1-10-AS1 (H1-10 antisense RNA 1) | protein interactions | 339942 | 4 | 1 | 19454 | 50 |
PTPN6 |
1.024e-02 | -4.58 | ZNF493 (zinc finger protein 493) | protein interactions | 284443 | 4 | 1 | 19454 | 50 |
RPL27A |
1.024e-02 | -4.58 | C10orf120 (chromosome 10 open reading frame 120) | protein interactions | 399814 | 4 | 1 | 19454 | 50 |
RPL35 |
1.024e-02 | -4.58 | LEKR1 (leucine, glutamate and lysine rich 1) | protein interactions | 389170 | 4 | 1 | 19454 | 50 |
NTRK1 |
1.029e-02 | -4.58 | ABCF1 (ATP binding cassette subfamily F member 1) | protein interactions | 23 | 175 | 3 | 19454 | 50 |
RPL27A,NTRK1,SYK |
1.030e-02 | -4.58 | NTKRECEPTOR | prints domains | PR01939 | 3 | 1 | 5227 | 18 |
NTRK1 |
1.030e-02 | -4.58 | SAPOSIN | prints domains | PR01797 | 3 | 1 | 5227 | 18 |
PSAP |
1.030e-02 | -4.58 | nucleoside-triphosphatase regulator activity | molecular function | GO:0060589 | 491 | 5 | 18094 | 49 |
RAPGEF6,ARAP1,RGL1,ELMO1,PDE6D |
1.030e-02 | -4.58 | GTPase regulator activity | molecular function | GO:0030695 | 491 | 5 | 18094 | 49 |
RGL1,ELMO1,PDE6D,RAPGEF6,ARAP1 |
1.042e-02 | -4.56 | DOCK2 (dedicator of cytokinesis 2) | protein interactions | 1794 | 60 | 2 | 19454 | 50 |
CARD10,ELMO1 |
1.043e-02 | -4.56 | cytoplasmic side of rough endoplasmic reticulum membrane | cellular component | GO:0098556 | 4 | 1 | 19108 | 50 |
RPS26 |
1.043e-02 | -4.56 | GAIT complex | cellular component | GO:0097452 | 4 | 1 | 19108 | 50 |
RPL13A |
1.046e-02 | -4.56 | BAG5 (BAG cochaperone 5) | protein interactions | 9529 | 333 | 4 | 19454 | 50 |
RPL12,CTSS,NTRK1,RPS3A |
1.047e-02 | -4.56 | Antigen activates B Cell Receptor (BCR) leading to generation of second messengers | REACTOME pathways | R-HSA-983695 | 39 | 2 | 10285 | 41 |
PTPN6,SYK |
1.049e-02 | -4.56 | regulation of response to external stimulus | biological process | GO:0032101 | 1116 | 8 | 18204 | 50 |
RBM47,SH2B3,CSF1R,SYK,CTSS,PTPN6,HCK,CD74 |
1.061e-02 | -4.55 | SYNPO (synaptopodin) | protein interactions | 11346 | 177 | 3 | 19454 | 50 |
SPECC1,BMP2K,GNAI2 |
1.064e-02 | -4.54 | defense response to symbiont | biological process | GO:0140546 | 894 | 7 | 18204 | 50 |
PTPN6,RPL13A,SYK,CD74,CSF1R,ITGAX,HCK |
1.064e-02 | -4.54 | regulation of anatomical structure morphogenesis | biological process | GO:0022603 | 894 | 7 | 18204 | 50 |
GAB1,ITGAX,HCK,DCC,HIPK2,ARAP1,CSF1R |
1.068e-02 | -4.54 | RALY (RALY heterogeneous nuclear ribonucleoprotein) | protein interactions | 22913 | 335 | 4 | 19454 | 50 |
RPL35,NTRK1,RPS20,CTSS |
1.073e-02 | -4.53 | positive regulation of response to biotic stimulus | biological process | GO:0002833 | 314 | 4 | 18204 | 50 |
CTSS,SYK,RBM47,HCK |
1.076e-02 | -4.53 | Gab1-4-like | interpro domains | IPR046355 | 4 | 1 | 18521 | 50 |
GAB1 |
1.076e-02 | -4.53 | SapB_2 | interpro domains | IPR008138 | 4 | 1 | 18521 | 50 |
PSAP |
1.076e-02 | -4.53 | Retinoid-X_rcpt/HNF4 | interpro domains | IPR000003 | 4 | 1 | 18521 | 50 |
RXRA |
1.077e-02 | -4.53 | PIK3CA (phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha) | protein interactions | 5290 | 178 | 3 | 19454 | 50 |
RPS20,NTRK1,CSF1R |
1.079e-02 | -4.53 | stem cell factor receptor binding | molecular function | GO:0005173 | 4 | 1 | 18094 | 49 |
SH2B3 |
1.079e-02 | -4.53 | CDP phosphatase activity | molecular function | GO:0036384 | 4 | 1 | 18094 | 49 |
ENTPD1 |
1.079e-02 | -4.53 | IDP phosphatase activity | molecular function | GO:1990003 | 4 | 1 | 18094 | 49 |
ENTPD1 |
1.079e-02 | -4.53 | NA_SULFATE | prosite domains | PS01271 | 3 | 1 | 12186 | 44 |
SLC13A1 |
1.079e-02 | -4.53 | SAP_A | prosite domains | PS51110 | 3 | 1 | 12186 | 44 |
PSAP |
1.089e-02 | -4.52 | CAPZA1 (capping actin protein of muscle Z-line subunit alpha 1) | protein interactions | 829 | 337 | 4 | 19454 | 50 |
RPS20,ARAP1,NTRK1,RXRA |
1.090e-02 | -4.52 | testis-germ_cell_tumour-seminoma | COSMIC cancer mutations | testis-germ_cell_tumour-seminoma | 648 | 6 | 16828 | 49 |
HIPK2,NTRK1,SYK,BMP2K,HCK,CSF1R |
1.094e-02 | -4.52 | NOP16 (NOP16 nucleolar protein) | protein interactions | 51491 | 179 | 3 | 19454 | 50 |
RPL18A,RPL35,RPL14 |
1.094e-02 | -4.52 | macrophage colony-stimulating factor signaling pathway | biological process | GO:0038145 | 4 | 1 | 18204 | 50 |
CSF1R |
1.094e-02 | -4.52 | regulation of mature B cell apoptotic process | biological process | GO:0002905 | 4 | 1 | 18204 | 50 |
CD74 |
1.094e-02 | -4.52 | positive regulation of mast cell cytokine production | biological process | GO:0032765 | 4 | 1 | 18204 | 50 |
SYK |
1.094e-02 | -4.52 | negative regulation of mast cell activation involved in immune response | biological process | GO:0033007 | 4 | 1 | 18204 | 50 |
PTPN6 |
1.094e-02 | -4.52 | negative regulation of mature B cell apoptotic process | biological process | GO:0002906 | 4 | 1 | 18204 | 50 |
CD74 |
1.094e-02 | -4.52 | respiratory burst after phagocytosis | biological process | GO:0045728 | 4 | 1 | 18204 | 50 |
HCK |
1.094e-02 | -4.52 | cellular response to molecule of fungal origin | biological process | GO:0071226 | 4 | 1 | 18204 | 50 |
SYK |
1.098e-02 | -4.51 | primitive_neuroectodermal_tumour-medulloblastoma | COSMIC cancer mutations | primitive_neuroectodermal_tumour-medulloblastoma | 15350 | 49 | 16828 | 49 |
RPL27A,ARAP1,PDE6D,CSF1R,PTPN6,RPL18A,RPL8,CADPS2,HCK,IVNS1ABP,RPL35,BMP2K,RGL1,DCC,RPS20,SLC13A1,RPS14,ADAM28,MAN1C1,RAPGEF6,SYK,RBM47,GNAI2,CD74,RPL34,ELMO1,RPL12,RPL14,ENTPD1,RPL36A,DIAPH2,FCHO2,ITGAX,CTSS,RPL37A,GAB1,ITM2B,HIPK2,NTRK1,RPL13A,RPS25,PSAP,CARD10,SH2B3,RPS3A,PDZRN3,RPS26,SPECC1,RXRA |
1.099e-02 | -4.51 | PH | smart domains | SM00233 | 259 | 4 | 9717 | 33 |
ARAP1,GAB1,CADPS2,SH2B3 |
1.100e-02 | -4.51 | ERBB3 (erb-b2 receptor tyrosine kinase 3) | protein interactions | 2065 | 338 | 4 | 19454 | 50 |
SH2B3,PTPN6,SYK,HCK |
1.101e-02 | -4.51 | SIRT7 (sirtuin 7) | protein interactions | 51547 | 735 | 6 | 19454 | 50 |
RPS14,RPL14,RPL8,RPL18A,RPS3A,RPS26 |
1.104e-02 | -4.51 | EZR (ezrin) | protein interactions | 7430 | 526 | 5 | 19454 | 50 |
NTRK1,DCC,GAB1,SYK,FCHO2 |
1.110e-02 | -4.50 | ZCCHC7 (zinc finger CCHC-type containing 7) | protein interactions | 84186 | 62 | 2 | 19454 | 50 |
RPL14,RPL8 |
1.113e-02 | -4.50 | PROTEIN_KINASE_ATP | prosite domains | PS00107 | 377 | 5 | 12186 | 44 |
HCK,NTRK1,CSF1R,SYK,HIPK2 |
1.113e-02 | -4.50 | vacuolar lumen | cellular component | GO:0005775 | 177 | 3 | 19108 | 50 |
CD74,CTSS,PSAP |
1.119e-02 | -4.49 | SapB_2 | pfam domains | PF03489 | 4 | 1 | 17795 | 50 |
PSAP |
1.121e-02 | -4.49 | YWHAB (tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein beta) | protein interactions | 7529 | 965 | 7 | 19454 | 50 |
NTRK1,PDE6D,GAB1,RAPGEF6,SPECC1,CD74,IVNS1ABP |
1.127e-02 | -4.49 | TCERG1 (transcription elongation regulator 1) | protein interactions | 10915 | 181 | 3 | 19454 | 50 |
NTRK1,PSAP,DIAPH2 |
1.144e-02 | -4.47 | PRPS1 (phosphoribosyl pyrophosphate synthetase 1) | protein interactions | 5631 | 182 | 3 | 19454 | 50 |
IVNS1ABP,HCK,NTRK1 |
1.144e-02 | -4.47 | FADS2 (fatty acid desaturase 2) | protein interactions | 9415 | 63 | 2 | 19454 | 50 |
RBM47,NTRK1 |
1.144e-02 | -4.47 | PAG1 (phosphoprotein membrane anchor with glycosphingolipid microdomains 1) | protein interactions | 55824 | 63 | 2 | 19454 | 50 |
PTPN6,SYK |
1.144e-02 | -4.47 | DOCK4 (dedicator of cytokinesis 4) | protein interactions | 9732 | 63 | 2 | 19454 | 50 |
NTRK1,ELMO1 |
1.145e-02 | -4.47 | TOP3B (DNA topoisomerase III beta) | protein interactions | 8940 | 1465 | 9 | 19454 | 50 |
SH2B3,RPS20,RPL27A,RAPGEF6,CARD10,RBM47,DIAPH2,ARAP1,GNAI2 |
1.146e-02 | -4.47 | cellular response to chemical stimulus | biological process | GO:0070887 | 2411 | 13 | 18204 | 50 |
NTRK1,CSF1R,CTSS,RPL13A,SYK,GAB1,CD74,RXRA,HIPK2,SH2B3,PTPN6,GNAI2,HCK |
1.156e-02 | -4.46 | activation of innate immune response | biological process | GO:0002218 | 171 | 3 | 18204 | 50 |
HCK,CTSS,SYK |
1.156e-02 | -4.46 | regulation of exocytosis | biological process | GO:0017157 | 171 | 3 | 18204 | 50 |
CADPS2,SYK,GNAI2 |
1.156e-02 | -4.46 | Hemostasis | REACTOME pathways | R-HSA-109582 | 632 | 7 | 10285 | 41 |
CD74,SYK,PTPN6,ITGAX,PSAP,GNAI2,SH2B3 |
1.156e-02 | -4.46 | MRPS7 (mitochondrial ribosomal protein S7) | protein interactions | 51081 | 343 | 4 | 19454 | 50 |
RBM47,NTRK1,RPL35,RPL8 |
1.160e-02 | -4.46 | haematopoietic_and_lymphoid_tissue-other-idiopathic_erythrocytosis | COSMIC cancer mutations | haematopoietic_and_lymphoid_tissue-other-idiopathic_erythrocytosis | 4 | 1 | 16828 | 49 |
SH2B3 |
1.160e-02 | -4.46 | idiopathic_erythrocytosis | COSMIC cancer mutations | idiopathic_erythrocytosis | 4 | 1 | 16828 | 49 |
SH2B3 |
1.161e-02 | -4.46 | GTF3C4 (general transcription factor IIIC subunit 4) | protein interactions | 9329 | 183 | 3 | 19454 | 50 |
IVNS1ABP,SYK,NTRK1 |
1.161e-02 | -4.46 | RO60 (Ro60, Y RNA binding protein) | protein interactions | 6738 | 183 | 3 | 19454 | 50 |
NTRK1,RPS3A,RPS25 |
1.170e-02 | -4.45 | positive regulation of phosphorus metabolic process | biological process | GO:0010562 | 697 | 6 | 18204 | 50 |
SYK,CARD10,NTRK1,CD74,HIPK2,CSF1R |
1.170e-02 | -4.45 | positive regulation of phosphate metabolic process | biological process | GO:0045937 | 697 | 6 | 18204 | 50 |
CARD10,NTRK1,HIPK2,CSF1R,SYK,CD74 |
1.178e-02 | -4.44 | Thyroid cancer | KEGG pathways | ko05216 | 29 | 2 | 7161 | 41 |
RXRA,NTRK1 |
1.178e-02 | -4.44 | Thyroid cancer | KEGG pathways | hsa05216 | 29 | 2 | 7161 | 41 |
RXRA,NTRK1 |
1.179e-02 | -4.44 | DGKE (diacylglycerol kinase epsilon) | protein interactions | 8526 | 64 | 2 | 19454 | 50 |
CD74,NTRK1 |
1.179e-02 | -4.44 | MICOS13 (mitochondrial contact site and cristae organizing system subunit 13) | protein interactions | 125988 | 64 | 2 | 19454 | 50 |
NTRK1,CTSS |
1.182e-02 | -4.44 | positive regulation of cytokine-mediated signaling pathway | biological process | GO:0001961 | 60 | 2 | 18204 | 50 |
CD74,RBM47 |
1.191e-02 | -4.43 | IQGAP1 (IQ motif containing GTPase activating protein 1) | protein interactions | 8826 | 536 | 5 | 19454 | 50 |
NTRK1,RPL14,RPS14,BMP2K,SPECC1 |
1.191e-02 | -4.43 | Signalling to STAT3 | REACTOME pathways | R-HSA-198745 | 3 | 1 | 10285 | 41 |
NTRK1 |
1.191e-02 | -4.43 | ARL13B-mediated ciliary trafficking of INPP5E | REACTOME pathways | R-HSA-5624958 | 3 | 1 | 10285 | 41 |
PDE6D |
1.191e-02 | -4.43 | Progressive trimming of alpha-1,2-linked mannose residues from Man9/8/7GlcNAc2 to produce Man5GlcNAc2 | REACTOME pathways | R-HSA-964827 | 3 | 1 | 10285 | 41 |
MAN1C1 |
1.212e-02 | -4.41 | regulation of protein phosphorylation | biological process | GO:0001932 | 917 | 7 | 18204 | 50 |
CD74,PTPN6,SYK,HIPK2,CSF1R,CARD10,NTRK1 |
1.213e-02 | -4.41 | PPAN (peter pan homolog) | protein interactions | 56342 | 186 | 3 | 19454 | 50 |
SYK,RPL37A,RPS3A |
1.215e-02 | -4.41 | APOBEC3F (apolipoprotein B mRNA editing enzyme catalytic subunit 3F) | protein interactions | 200316 | 65 | 2 | 19454 | 50 |
RPL35,RBM47 |
1.215e-02 | -4.41 | LPAR3 (lysophosphatidic acid receptor 3) | protein interactions | 23566 | 65 | 2 | 19454 | 50 |
GNAI2,CD74 |
1.215e-02 | -4.41 | MAGEB10 (MAGE family member B10) | protein interactions | 139422 | 65 | 2 | 19454 | 50 |
RPL18A,RPL12 |
1.220e-02 | -4.41 | negative regulation of G protein-coupled receptor signaling pathway | biological process | GO:0045744 | 61 | 2 | 18204 | 50 |
SH2B3,GNAI2 |
1.225e-02 | -4.40 | transmembrane receptor protein tyrosine kinase activity | molecular function | GO:0004714 | 62 | 2 | 18094 | 49 |
NTRK1,CSF1R |
1.227e-02 | -4.40 | RBX1 (ring-box 1) | protein interactions | 9978 | 540 | 5 | 19454 | 50 |
RPL27A,RPL13A,RPL8,RAPGEF6,RPL12 |
1.228e-02 | -4.40 | ovary-carcinoma-clear_cell_carcinoma | COSMIC cancer mutations | ovary-carcinoma-clear_cell_carcinoma | 665 | 6 | 16828 | 49 |
CSF1R,HCK,SYK,BMP2K,NTRK1,HIPK2 |
1.230e-02 | -4.40 | regulation of interleukin-6 production | biological process | GO:0032675 | 175 | 3 | 18204 | 50 |
PTPN6,SYK,CD74 |
1.230e-02 | -4.40 | KLF5 (KLF transcription factor 5) | protein interactions | 688 | 187 | 3 | 19454 | 50 |
RPL36A,RXRA,RPL37A |
1.238e-02 | -4.39 | EPHA2 (EPH receptor A2) | protein interactions | 1969 | 350 | 4 | 19454 | 50 |
GAB1,HCK,CSF1R,NTRK1 |
1.238e-02 | -4.39 | GANAB (glucosidase II alpha subunit) | protein interactions | 23193 | 350 | 4 | 19454 | 50 |
IVNS1ABP,CTSS,CD74,NTRK1 |
1.249e-02 | -4.38 | blood coagulation | biological process | GO:0007596 | 176 | 3 | 18204 | 50 |
PTPN6,SYK,ENTPD1 |
1.249e-02 | -4.38 | back | COSMIC cancer mutations | back | 310 | 4 | 16828 | 49 |
DCC,NTRK1,CSF1R,ADAM28 |
1.250e-02 | -4.38 | HLA-DRB3 (major histocompatibility complex, class II, DR beta 3) | protein interactions | 3125 | 66 | 2 | 19454 | 50 |
ITM2B,CD74 |
1.257e-02 | -4.38 | Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB) | gene3d domains | 2.30.29.30 | 431 | 5 | 14470 | 47 |
ARAP1,GAB1,ELMO1,CADPS2,SH2B3 |
1.261e-02 | -4.37 | CDH1 (cadherin 1) | protein interactions | 999 | 757 | 6 | 19454 | 50 |
RPL14,RPL34,GAB1,SPECC1,RPL36A,RPS26 |
1.262e-02 | -4.37 | LARS1 (leucyl-tRNA synthetase 1) | protein interactions | 51520 | 352 | 4 | 19454 | 50 |
NTRK1,SPECC1,RPL12,GNAI2 |
1.262e-02 | -4.37 | clear_cell_carcinoma | COSMIC cancer mutations | clear_cell_carcinoma | 669 | 6 | 16828 | 49 |
HIPK2,NTRK1,SYK,BMP2K,HCK,CSF1R |
1.266e-02 | -4.37 | MRPL27 (mitochondrial ribosomal protein L27) | protein interactions | 51264 | 189 | 3 | 19454 | 50 |
RPS3A,RPL13A,RPL35 |
1.274e-02 | -4.36 | SRP14 (signal recognition particle 14) | protein interactions | 6727 | 353 | 4 | 19454 | 50 |
RPL35,RPL14,PTPN6,RPS25 |
1.279e-02 | -4.36 | ABCD2 (ATP binding cassette subfamily D member 2) | protein interactions | 225 | 5 | 1 | 19454 | 50 |
NTRK1 |
1.279e-02 | -4.36 | SLC5A9 (solute carrier family 5 member 9) | protein interactions | 200010 | 5 | 1 | 19454 | 50 |
NTRK1 |
1.279e-02 | -4.36 | ADH4 (alcohol dehydrogenase 4 (class II), pi polypeptide) | protein interactions | 127 | 5 | 1 | 19454 | 50 |
RPL35 |
1.279e-02 | -4.36 | WNT8B (Wnt family member 8B) | protein interactions | 7479 | 5 | 1 | 19454 | 50 |
RPL18A |
1.279e-02 | -4.36 | ZNF253 (zinc finger protein 253) | protein interactions | 56242 | 5 | 1 | 19454 | 50 |
RPL27A |
1.279e-02 | -4.36 | PAGE2B (PAGE family member 2B) | protein interactions | 389860 | 5 | 1 | 19454 | 50 |
RPL36A |
1.279e-02 | -4.36 | ADGRF5 (adhesion G protein-coupled receptor F5) | protein interactions | 221395 | 5 | 1 | 19454 | 50 |
RPL13A |
1.279e-02 | -4.36 | CHRM1 (cholinergic receptor muscarinic 1) | protein interactions | 1128 | 5 | 1 | 19454 | 50 |
GNAI2 |
1.282e-02 | -4.36 | SRSF1 (serine and arginine rich splicing factor 1) | protein interactions | 6426 | 546 | 5 | 19454 | 50 |
PTPN6,NTRK1,RPL18A,GNAI2,RPL8 |
1.284e-02 | -4.36 | MRPS18C (mitochondrial ribosomal protein S18C) | protein interactions | 51023 | 190 | 3 | 19454 | 50 |
RPL13A,RPL27A,RPL35 |
1.286e-02 | -4.35 | TRIP6 (thyroid hormone receptor interactor 6) | protein interactions | 7205 | 354 | 4 | 19454 | 50 |
HCK,GNAI2,RPS14,PTPN6 |
1.287e-02 | -4.35 | SHC3 (SHC adaptor protein 3) | protein interactions | 53358 | 67 | 2 | 19454 | 50 |
NTRK1,GAB1 |
1.287e-02 | -4.35 | ASAP1 (ArfGAP with SH3 domain, ankyrin repeat and PH domain 1) | protein interactions | 50807 | 67 | 2 | 19454 | 50 |
HCK,NTRK1 |
1.287e-02 | -4.35 | MIOS (meiosis regulator for oocyte development) | protein interactions | 54468 | 67 | 2 | 19454 | 50 |
NTRK1,RXRA |
1.287e-02 | -4.35 | coagulation | biological process | GO:0050817 | 178 | 3 | 18204 | 50 |
SYK,PTPN6,ENTPD1 |
1.291e-02 | -4.35 | VIRMA (vir like m6A methyltransferase associated) | protein interactions | 25962 | 2914 | 14 | 19454 | 50 |
GAB1,SPECC1,RAPGEF6,RPL12,HIPK2,RBM47,BMP2K,RPS14,RGL1,NTRK1,CSF1R,IVNS1ABP,GNAI2,DIAPH2 |
1.298e-02 | -4.34 | positive regulation of interleukin-8 production | biological process | GO:0032757 | 63 | 2 | 18204 | 50 |
SYK,CD74 |
1.302e-02 | -4.34 | apolipoprotein B mRNA editing enzyme complex | cellular component | GO:0030895 | 5 | 1 | 19108 | 50 |
RBM47 |
1.302e-02 | -4.34 | CBM complex | cellular component | GO:0032449 | 5 | 1 | 19108 | 50 |
CARD10 |
1.302e-02 | -4.34 | alpha-beta T cell receptor complex | cellular component | GO:0042105 | 5 | 1 | 19108 | 50 |
PTPN6 |
1.302e-02 | -4.34 | B cell receptor complex | cellular component | GO:0019815 | 5 | 1 | 19108 | 50 |
SYK |
1.302e-02 | -4.34 | endolysosome lumen | cellular component | GO:0036021 | 5 | 1 | 19108 | 50 |
CTSS |
1.302e-02 | -4.34 | endocytic vesicle | cellular component | GO:0030139 | 349 | 4 | 19108 | 50 |
SYK,CTSS,CD74,RAPGEF6 |
1.302e-02 | -4.34 | PEX5 (peroxisomal biogenesis factor 5) | protein interactions | 5830 | 191 | 3 | 19454 | 50 |
ENTPD1,PSAP,RPL14 |
1.311e-02 | -4.33 | TRIM23 (tripartite motif containing 23) | protein interactions | 373 | 356 | 4 | 19454 | 50 |
RPL27A,RPL8,RPS14,RPL18A |
1.311e-02 | -4.33 | DNAJC1 (DnaJ heat shock protein family (Hsp40) member C1) | protein interactions | 64215 | 356 | 4 | 19454 | 50 |
RPL8,RPL37A,RPL12,RPL13A |
1.317e-02 | -4.33 | upper_leg | COSMIC cancer mutations | upper_leg | 880 | 7 | 16828 | 49 |
NTRK1,SLC13A1,ELMO1,DCC,MAN1C1,CSF1R,ADAM28 |
1.332e-02 | -4.32 | regulation of vesicle-mediated transport | biological process | GO:0060627 | 516 | 5 | 18204 | 50 |
SYK,GNAI2,CADPS2,HCK,BMP2K |
1.339e-02 | -4.31 | LTN1 (listerin E3 ubiquitin protein ligase 1) | protein interactions | 26046 | 193 | 3 | 19454 | 50 |
IVNS1ABP,NTRK1,CD74 |
1.339e-02 | -4.31 | MRPL18 (mitochondrial ribosomal protein L18) | protein interactions | 29074 | 193 | 3 | 19454 | 50 |
RPL35,RPL27A,RPL13A |
1.339e-02 | -4.31 | UPF1 (UPF1 RNA helicase and ATPase) | protein interactions | 5976 | 552 | 5 | 19454 | 50 |
RPS20,RBM47,NTRK1,RPS3A,IVNS1ABP |
1.341e-02 | -4.31 | rRNA binding | molecular function | GO:0019843 | 65 | 2 | 18094 | 49 |
RPL8,RPL12 |
1.343e-02 | -4.31 | HnRNP_R/Q_splicing_fac | interpro domains | IPR006535 | 5 | 1 | 18521 | 50 |
RBM47 |
1.343e-02 | -4.31 | SLC13A/DASS | interpro domains | IPR001898 | 5 | 1 | 18521 | 50 |
SLC13A1 |
1.347e-02 | -4.31 | large ribosomal subunit rRNA binding | molecular function | GO:0070180 | 5 | 1 | 18094 | 49 |
RPL12 |
1.347e-02 | -4.31 | ganglioside binding | molecular function | GO:0035594 | 5 | 1 | 18094 | 49 |
PSAP |
1.347e-02 | -4.31 | neurotrophin receptor activity | molecular function | GO:0005030 | 5 | 1 | 18094 | 49 |
NTRK1 |
1.357e-02 | -4.30 | TUBB2B (tubulin beta 2B class IIb) | protein interactions | 347733 | 194 | 3 | 19454 | 50 |
RPL18A,RPL35,NTRK1 |
1.361e-02 | -4.30 | RPS4Y2 (ribosomal protein S4 Y-linked 2) | protein interactions | 140032 | 69 | 2 | 19454 | 50 |
RPL14,RPS3A |
1.361e-02 | -4.30 | EVL (Enah/Vasp-like) | protein interactions | 51466 | 69 | 2 | 19454 | 50 |
FYB1,HCK |
1.366e-02 | -4.29 | plasma membrane signaling receptor complex | cellular component | GO:0098802 | 191 | 3 | 19108 | 50 |
SYK,PTPN6,ITGAX |
1.366e-02 | -4.29 | hemostasis | biological process | GO:0007599 | 182 | 3 | 18204 | 50 |
PTPN6,SYK,ENTPD1 |
1.366e-02 | -4.29 | thrombopoietin-mediated signaling pathway | biological process | GO:0038163 | 5 | 1 | 18204 | 50 |
SH2B3 |
1.366e-02 | -4.29 | epididymis development | biological process | GO:1905867 | 5 | 1 | 18204 | 50 |
PTPN6 |
1.366e-02 | -4.29 | regulation of mast cell activation involved in immune response | biological process | GO:0033006 | 5 | 1 | 18204 | 50 |
PTPN6 |
1.366e-02 | -4.29 | negative regulation of adenylate cyclase-activating adrenergic receptor signaling pathway | biological process | GO:0071878 | 5 | 1 | 18204 | 50 |
GNAI2 |
1.366e-02 | -4.29 | response to molecule of fungal origin | biological process | GO:0002238 | 5 | 1 | 18204 | 50 |
SYK |
1.371e-02 | -4.29 | RETINOIDXR | prints domains | PR00545 | 4 | 1 | 5227 | 18 |
RXRA |
1.375e-02 | -4.29 | skin-upper_back-malignant_melanoma | COSMIC cancer mutations | skin-upper_back-malignant_melanoma | 319 | 4 | 16828 | 49 |
DCC,GAB1,ELMO1,NTRK1 |
1.376e-02 | -4.29 | MAT2A (methionine adenosyltransferase 2A) | protein interactions | 4144 | 195 | 3 | 19454 | 50 |
RPL35,RPS3A,NTRK1 |
1.376e-02 | -4.29 | Myh9 (myosin, heavy polypeptide 9, non-muscle) | protein interactions | 17886 | 195 | 3 | 19454 | 50 |
SPECC1,FCHO2,BMP2K |
1.377e-02 | -4.29 | regulation of interleukin-10 production | biological process | GO:0032653 | 65 | 2 | 18204 | 50 |
SYK,RBM47 |
1.383e-02 | -4.28 | NTRK1 (neurotrophic receptor tyrosine kinase 1) | protein interactions | 4914 | 2058 | 11 | 19454 | 50 |
RPS25,NTRK1,ELMO1,GAB1,RPL14,ARAP1,PTPN6,RPL13A,RPS3A,HIPK2,RPL8 |
1.387e-02 | -4.28 | CREBBP (CREB binding protein) | protein interactions | 1387 | 557 | 5 | 19454 | 50 |
HCK,HIPK2,RPL35,RPS20,RXRA |
1.395e-02 | -4.27 | DNAJC19 (DnaJ heat shock protein family (Hsp40) member C19) | protein interactions | 131118 | 196 | 3 | 19454 | 50 |
RPL8,RPL34,RPL18A |
1.395e-02 | -4.27 | BLK (BLK proto-oncogene, Src family tyrosine kinase) | protein interactions | 640 | 196 | 3 | 19454 | 50 |
RPL37A,GAB1,HCK |
1.397e-02 | -4.27 | Na_sulph_symp | pfam domains | PF00939 | 5 | 1 | 17795 | 50 |
SLC13A1 |
1.399e-02 | -4.27 | NGFR (nerve growth factor receptor) | protein interactions | 4804 | 70 | 2 | 19454 | 50 |
HIPK2,NTRK1 |
1.399e-02 | -4.27 | IL6ST (interleukin 6 cytokine family signal transducer) | protein interactions | 3572 | 70 | 2 | 19454 | 50 |
PTPN6,HCK |
1.399e-02 | -4.27 | ALCAM (activated leukocyte cell adhesion molecule) | protein interactions | 214 | 70 | 2 | 19454 | 50 |
NTRK1,SYK |
1.399e-02 | -4.27 | SBNO1 (strawberry notch homolog 1) | protein interactions | 55206 | 70 | 2 | 19454 | 50 |
IVNS1ABP,NTRK1 |
1.399e-02 | -4.27 | CAVIN3 (caveolae associated protein 3) | protein interactions | 112464 | 70 | 2 | 19454 | 50 |
RPS26,RPS3A |
1.399e-02 | -4.27 | ACTN4 (actinin alpha 4) | protein interactions | 81 | 363 | 4 | 19454 | 50 |
PTPN6,CTSS,NTRK1,RPS3A |
1.405e-02 | -4.27 | regulation of immune response | biological process | GO:0050776 | 944 | 7 | 18204 | 50 |
RBM47,FYB1,HCK,CD74,SYK,CTSS,PTPN6 |
1.408e-02 | -4.26 | regulation of hydrolase activity | biological process | GO:0051336 | 726 | 6 | 18204 | 50 |
ARAP1,RAPGEF6,NTRK1,CTSS,SYK,PSAP |
1.414e-02 | -4.26 | PIK3R3 (phosphoinositide-3-kinase regulatory subunit 3) | protein interactions | 8503 | 197 | 3 | 19454 | 50 |
NTRK1,HCK,GAB1 |
1.415e-02 | -4.26 | Alpha-synuclein signaling | Pathway Interaction DB | alphasynuclein_pathway | 32 | 2 | 2226 | 13 |
HCK,SYK |
1.418e-02 | -4.26 | homotypic cell-cell adhesion | biological process | GO:0034109 | 66 | 2 | 18204 | 50 |
PTPN6,ENTPD1 |
1.425e-02 | -4.25 | KRR1 (KRR1 small subunit processome component homolog) | protein interactions | 11103 | 365 | 4 | 19454 | 50 |
RPS14,RPL35,RPS3A,RPL13A |
1.427e-02 | -4.25 | positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction | biological process | GO:0051897 | 185 | 3 | 18204 | 50 |
PTPN6,NTRK1,CSF1R |
1.427e-02 | -4.25 | C1QBP (complement C1q binding protein) | protein interactions | 708 | 778 | 6 | 19454 | 50 |
NTRK1,RPL27A,GAB1,RPS14,PSAP,RPL8 |
1.427e-02 | -4.25 | kinase activity | molecular function | GO:0016301 | 739 | 6 | 18094 | 49 |
HIPK2,SYK,CSF1R,BMP2K,NTRK1,HCK |
1.430e-02 | -4.25 | B Cell Receptor Signaling Pathway | WikiPathways | WP23 | 98 | 3 | 5310 | 28 |
SYK,GAB1,PTPN6 |
1.430e-02 | -4.25 | PARP1 (poly(ADP-ribose) polymerase 1) | protein interactions | 142 | 1260 | 8 | 19454 | 50 |
RPL14,RPL35,NTRK1,RPL27A,IVNS1ABP,HIPK2,RPS3A,RXRA |
1.433e-02 | -4.25 | MRPL45 (mitochondrial ribosomal protein L45) | protein interactions | 84311 | 198 | 3 | 19454 | 50 |
RPL35,RPL27A,RPL13A |
1.437e-02 | -4.24 | ZDHHC18 (zinc finger DHHC-type palmitoyltransferase 18) | protein interactions | 84243 | 71 | 2 | 19454 | 50 |
RPS25,RXRA |
1.437e-02 | -4.24 | ZSCAN25 (zinc finger and SCAN domain containing 25) | protein interactions | 221785 | 71 | 2 | 19454 | 50 |
CARD10,RPL14 |
1.447e-02 | -4.24 | positive regulation of angiogenesis | biological process | GO:0045766 | 186 | 3 | 18204 | 50 |
GAB1,ITGAX,HIPK2 |
1.451e-02 | -4.23 | PLEKHA4 (pleckstrin homology domain containing A4) | protein interactions | 57664 | 2955 | 14 | 19454 | 50 |
RPL37A,RAPGEF6,RPL8,RPL12,RPL18A,RPL27A,RPS25,RPL14,RPL35,BMP2K,RPL34,RPS26,GNAI2,SYK |
1.451e-02 | -4.23 | SMAD2 (SMAD family member 2) | protein interactions | 4087 | 367 | 4 | 19454 | 50 |
PSAP,RXRA,RPS14,HIPK2 |
1.453e-02 | -4.23 | MRPL47 (mitochondrial ribosomal protein L47) | protein interactions | 57129 | 199 | 3 | 19454 | 50 |
RPL27A,RPL13A,RPL35 |
1.459e-02 | -4.23 | positive regulation of response to cytokine stimulus | biological process | GO:0060760 | 67 | 2 | 18204 | 50 |
RBM47,CD74 |
1.476e-02 | -4.22 | ESD (esterase D) | protein interactions | 2098 | 72 | 2 | 19454 | 50 |
NTRK1,DIAPH2 |
1.476e-02 | -4.22 | ZDHHC23 (zinc finger DHHC-type palmitoyltransferase 23) | protein interactions | 254887 | 72 | 2 | 19454 | 50 |
RXRA,RPS25 |
1.476e-02 | -4.22 | ITGB2 (integrin subunit beta 2) | protein interactions | 3689 | 72 | 2 | 19454 | 50 |
ITGAX,SYK |
1.476e-02 | -4.22 | Ppp1cb (protein phosphatase 1 catalytic subunit beta) | protein interactions | 19046 | 72 | 2 | 19454 | 50 |
BMP2K,SPECC1 |
1.476e-02 | -4.22 | MINDY4 (MINDY lysine 48 deubiquitinase 4) | protein interactions | 84182 | 72 | 2 | 19454 | 50 |
RPL14,RPL13A |
1.479e-02 | -4.21 | haematopoietic_and_lymphoid_tissue-haematopoietic_neoplasm-acute_myeloid_leukaemia_associated_with_MDS | COSMIC cancer mutations | haematopoietic_and_lymphoid_tissue-haematopoietic_neoplasm-acute_myeloid_leukaemia_associated_with_MDS | 177 | 3 | 16828 | 49 |
HIPK2,SH2B3,CSF1R |
1.479e-02 | -4.21 | acute_myeloid_leukaemia_associated_with_MDS | COSMIC cancer mutations | acute_myeloid_leukaemia_associated_with_MDS | 177 | 3 | 16828 | 49 |
SH2B3,CSF1R,HIPK2 |
1.483e-02 | -4.21 | cytoplasmic side of membrane | cellular component | GO:0098562 | 197 | 3 | 19108 | 50 |
GNAI2,HCK,RPS26 |
1.491e-02 | -4.21 | MYO1C (myosin IC) | protein interactions | 4641 | 370 | 4 | 19454 | 50 |
CARD10,SPECC1,CTSS,NTRK1 |
1.491e-02 | -4.21 | MRPS9 (mitochondrial ribosomal protein S9) | protein interactions | 64965 | 370 | 4 | 19454 | 50 |
RPL35,NTRK1,RPL27A,RBM47 |
1.501e-02 | -4.20 | ribosomal large subunit biogenesis | biological process | GO:0042273 | 68 | 2 | 18204 | 50 |
RPL14,RPL35 |
1.502e-02 | -4.20 | regulation of protein metabolic process | biological process | GO:0051246 | 2218 | 12 | 18204 | 50 |
PTPN6,CTSS,SYK,RPL13A,CD74,ITM2B,NTRK1,CARD10,CSF1R,RPS14,HIPK2,IVNS1ABP |
1.504e-02 | -4.20 | SLFN11 (schlafen family member 11) | protein interactions | 91607 | 371 | 4 | 19454 | 50 |
RPS25,RPL14,RPS14,PDZRN3 |
1.508e-02 | -4.19 | upper_back | COSMIC cancer mutations | upper_back | 328 | 4 | 16828 | 49 |
NTRK1,DCC,GAB1,ELMO1 |
1.510e-02 | -4.19 | positive regulation of vasculature development | biological process | GO:1904018 | 189 | 3 | 18204 | 50 |
GAB1,HIPK2,ITGAX |
1.515e-02 | -4.19 | STAMBPL1 (STAM binding protein like 1) | protein interactions | 57559 | 73 | 2 | 19454 | 50 |
BMP2K,RBM47 |
1.515e-02 | -4.19 | PANK4 (pantothenate kinase 4 (inactive)) | protein interactions | 55229 | 73 | 2 | 19454 | 50 |
NTRK1,PTPN6 |
1.515e-02 | -4.19 | ZNF689 (zinc finger protein 689) | protein interactions | 115509 | 73 | 2 | 19454 | 50 |
RPL18A,RPS3A |
1.520e-02 | -4.19 | response to organic substance | biological process | GO:0010033 | 2498 | 13 | 18204 | 50 |
SH2B3,HCK,GNAI2,PTPN6,CSF1R,MAN1C1,NTRK1,RXRA,CD74,GAB1,SYK,RPL13A,CTSS |
1.526e-02 | -4.18 | regulation of response to biotic stimulus | biological process | GO:0002831 | 534 | 5 | 18204 | 50 |
SYK,CTSS,PTPN6,HCK,RBM47 |
1.526e-02 | -4.18 | positive regulation of multicellular organismal process | biological process | GO:0051240 | 1691 | 10 | 18204 | 50 |
RBM47,CSF1R,HIPK2,NTRK1,RXRA,ITGAX,CD74,GAB1,SYK,PTPN6 |
1.531e-02 | -4.18 | IPO4 (importin 4) | protein interactions | 79711 | 203 | 3 | 19454 | 50 |
CTSS,RPS3A,NTRK1 |
1.532e-02 | -4.18 | ADCY1 (adenylate cyclase 1) | protein interactions | 107 | 6 | 1 | 19454 | 50 |
GNAI2 |
1.532e-02 | -4.18 | Bace1 (beta-site APP cleaving enzyme 1) | protein interactions | 23821 | 6 | 1 | 19454 | 50 |
PSAP |
1.532e-02 | -4.18 | TLE6 (TLE family member 6, subcortical maternal complex member) | protein interactions | 79816 | 6 | 1 | 19454 | 50 |
RPL14 |
1.532e-02 | -4.18 | C8orf48 (chromosome 8 open reading frame 48) | protein interactions | 157773 | 6 | 1 | 19454 | 50 |
CARD10 |
1.532e-02 | -4.18 | echA1 (enoyl-CoA hydratase EchA1) | protein interactions | 886723 | 6 | 1 | 19454 | 50 |
PTPN6 |
1.532e-02 | -4.18 | ANKRD20A2P (ankyrin repeat domain 20 family member A2, pseudogene) | protein interactions | 441430 | 6 | 1 | 19454 | 50 |
PDZRN3 |
1.532e-02 | -4.18 | HTNVsSgp1 (hypothetical protein) | protein interactions | 2943078 | 6 | 1 | 19454 | 50 |
HIPK2 |
1.532e-02 | -4.18 | Get3 (guided entry of tail-anchored proteins factor 3, ATPase) | protein interactions | 56495 | 6 | 1 | 19454 | 50 |
IVNS1ABP |
1.532e-02 | -4.18 | Ncoa2 (nuclear receptor coactivator 2) | protein interactions | 17978 | 6 | 1 | 19454 | 50 |
RXRA |
1.532e-02 | -4.18 | Kif7 (kinesin family member 7) | protein interactions | 16576 | 6 | 1 | 19454 | 50 |
CARD10 |
1.532e-02 | -4.18 | Fip1l1 (factor interacting with PAPOLA and CPSF1) | protein interactions | 66899 | 6 | 1 | 19454 | 50 |
RPL13A |
1.532e-02 | -4.18 | ZNF613 (zinc finger protein 613) | protein interactions | 79898 | 6 | 1 | 19454 | 50 |
CARD10 |
1.532e-02 | -4.18 | CD300LF (CD300 molecule like family member f) | protein interactions | 146722 | 6 | 1 | 19454 | 50 |
PTPN6 |
1.543e-02 | -4.17 | scaffold protein binding | molecular function | GO:0097110 | 70 | 2 | 18094 | 49 |
PSAP,SYK |
1.544e-02 | -4.17 | innate immune response | biological process | GO:0045087 | 741 | 6 | 18204 | 50 |
PTPN6,SYK,RPL13A,CSF1R,CD74,HCK |
1.549e-02 | -4.17 | seminoma | COSMIC cancer mutations | seminoma | 700 | 6 | 16828 | 49 |
HCK,CSF1R,NTRK1,SYK,HIPK2,BMP2K |
1.551e-02 | -4.17 | TIPARP (TCDD inducible poly(ADP-ribose) polymerase) | protein interactions | 25976 | 1540 | 9 | 19454 | 50 |
RPL12,RPS26,DIAPH2,RPL13A,ARAP1,RPL37A,RPL14,RPL35,RPL34 |
1.552e-02 | -4.17 | ARPC1B (actin related protein 2/3 complex subunit 1B) | protein interactions | 10095 | 204 | 3 | 19454 | 50 |
NTRK1,RPL12,RPL35 |
1.552e-02 | -4.17 | INPPL1 (inositol polyphosphate phosphatase like 1) | protein interactions | 3636 | 204 | 3 | 19454 | 50 |
GAB1,CSF1R,NTRK1 |
1.554e-02 | -4.16 | RNF6 (ring finger protein 6) | protein interactions | 6049 | 74 | 2 | 19454 | 50 |
GNAI2,PTPN6 |
1.560e-02 | -4.16 | mRNA editing complex | cellular component | GO:0045293 | 6 | 1 | 19108 | 50 |
RBM47 |
1.561e-02 | -4.16 | CDC42 (cell division cycle 42) | protein interactions | 998 | 1280 | 8 | 19454 | 50 |
RPS20,PDE6D,SPECC1,DIAPH2,ARAP1,RPL12,FCHO2,IVNS1ABP |
1.567e-02 | -4.16 | small-subunit processome | cellular component | GO:0032040 | 73 | 2 | 19108 | 50 |
RPS3A,RPS14 |
1.572e-02 | -4.15 | MRPS30 (mitochondrial ribosomal protein S30) | protein interactions | 10884 | 205 | 3 | 19454 | 50 |
RPL27A,RPL13A,RPL35 |
1.576e-02 | -4.15 | Cell-Cell communication | REACTOME pathways | R-HSA-1500931 | 133 | 3 | 10285 | 41 |
PTPN6,DCC,FYB1 |
1.585e-02 | -4.14 | antigen processing and presentation of peptide antigen | biological process | GO:0048002 | 70 | 2 | 18204 | 50 |
CD74,CTSS |
1.585e-02 | -4.14 | positive regulation of reactive oxygen species metabolic process | biological process | GO:2000379 | 70 | 2 | 18204 | 50 |
SYK,GNAI2 |
1.592e-02 | -4.14 | cellular process | biological process | GO:0009987 | 14996 | 47 | 18204 | 50 |
PDZRN3,IVNS1ABP,CSF1R,ARAP1,RPL8,ELMO1,RXRA,SPECC1,CD74,FCHO2,RPL13A,RPL37A,CTSS,RPS26,SH2B3,RPS3A,RAPGEF6,RPS14,DCC,RPL34,RPS20,RPS25,ENTPD1,DIAPH2,PTPN6,RPL35,BMP2K,CARD10,RPL14,NTRK1,MAN1C1,RPL27A,FYB1,ITGAX,SYK,GAB1,RBM47,RPL36A,HIPK2,SLC13A1,HCK,RPL12,PSAP,RPL18A,GNAI2,RGL1,CADPS2 |
1.592e-02 | -4.14 | MRPL9 (mitochondrial ribosomal protein L9) | protein interactions | 65005 | 206 | 3 | 19454 | 50 |
RPL13A,RPL27A,RPL35 |
1.594e-02 | -4.14 | cell development | biological process | GO:0048468 | 2236 | 12 | 18204 | 50 |
CSF1R,NTRK1,CD74,SYK,SH2B3,RBM47,RAPGEF6,RPS14,HIPK2,DCC,DIAPH2,PTPN6 |
1.594e-02 | -4.14 | SECISBP2 (SECIS binding protein 2) | protein interactions | 79048 | 75 | 2 | 19454 | 50 |
RBM47,RPS20 |
1.600e-02 | -4.13 | SMC3 (structural maintenance of chromosomes 3) | protein interactions | 9126 | 378 | 4 | 19454 | 50 |
IVNS1ABP,RPL37A,RPL14,NTRK1 |
1.609e-02 | -4.13 | Saposin-like | interpro domains | IPR011001 | 6 | 1 | 18521 | 50 |
PSAP |
1.609e-02 | -4.13 | ELMO_dom | interpro domains | IPR006816 | 6 | 1 | 18521 | 50 |
ELMO1 |
1.613e-02 | -4.13 | ZFP36L2 (ZFP36 ring finger protein like 2) | protein interactions | 678 | 207 | 3 | 19454 | 50 |
RPS3A,IVNS1ABP,RPL35 |
1.614e-02 | -4.13 | Formin, FH3 diaphanous domain | gene3d domains | 1.10.238.150 | 5 | 1 | 14470 | 47 |
DIAPH2 |
1.614e-02 | -4.13 | CTPase activity | molecular function | GO:0043273 | 6 | 1 | 18094 | 49 |
ENTPD1 |
1.614e-02 | -4.13 | ADP phosphatase activity | molecular function | GO:0043262 | 6 | 1 | 18094 | 49 |
ENTPD1 |
1.614e-02 | -4.13 | retinoic acid-responsive element binding | molecular function | GO:0044323 | 6 | 1 | 18094 | 49 |
RXRA |
1.614e-02 | -4.13 | GPI-linked ephrin receptor activity | molecular function | GO:0005004 | 6 | 1 | 18094 | 49 |
NTRK1 |
1.614e-02 | -4.13 | nerve growth factor binding | molecular function | GO:0048406 | 6 | 1 | 18094 | 49 |
NTRK1 |
1.614e-02 | -4.13 | type 1 angiotensin receptor binding | molecular function | GO:0031702 | 6 | 1 | 18094 | 49 |
ARAP1 |
1.615e-02 | -4.13 | ABCE1 (ATP binding cassette subfamily E member 1) | protein interactions | 6059 | 379 | 4 | 19454 | 50 |
NTRK1,RPS3A,RPS20,RPS25 |
1.633e-02 | -4.11 | BCL2L1 (BCL2 like 1) | protein interactions | 598 | 208 | 3 | 19454 | 50 |
RPS26,RPL8,RPL12 |
1.635e-02 | -4.11 | CD1B (CD1b molecule) | protein interactions | 910 | 76 | 2 | 19454 | 50 |
PSAP,ITM2B |
1.637e-02 | -4.11 | positive regulation of vitamin D receptor signaling pathway | biological process | GO:0070564 | 6 | 1 | 18204 | 50 |
RXRA |
1.637e-02 | -4.11 | positive regulation of prostaglandin biosynthetic process | biological process | GO:0031394 | 6 | 1 | 18204 | 50 |
CD74 |
1.637e-02 | -4.11 | regulation of endothelial tube morphogenesis | biological process | GO:1901509 | 6 | 1 | 18204 | 50 |
ITGAX |
1.637e-02 | -4.11 | positive regulation of macrophage proliferation | biological process | GO:0120041 | 6 | 1 | 18204 | 50 |
CSF1R |
1.637e-02 | -4.11 | embryonic retina morphogenesis in camera-type eye | biological process | GO:0060059 | 6 | 1 | 18204 | 50 |
HIPK2 |
1.637e-02 | -4.11 | regulation of mast cell cytokine production | biological process | GO:0032763 | 6 | 1 | 18204 | 50 |
SYK |
1.664e-02 | -4.10 | cell-cell adhesion | biological process | GO:0098609 | 546 | 5 | 18204 | 50 |
PTPN6,DCC,SYK,ITGAX,ENTPD1 |
1.672e-02 | -4.09 | Cell surface interactions at the vascular wall | REACTOME pathways | R-HSA-202733 | 136 | 3 | 10285 | 41 |
CD74,ITGAX,PTPN6 |
1.674e-02 | -4.09 | ELMO_CED12 | pfam domains | PF04727 | 6 | 1 | 17795 | 50 |
ELMO1 |
1.676e-02 | -4.09 | FBXO42 (F-box protein 42) | protein interactions | 54455 | 77 | 2 | 19454 | 50 |
RPS3A,RPL8 |
1.677e-02 | -4.09 | plasma membrane | cellular component | GO:0005886 | 5538 | 22 | 19108 | 50 |
HCK,SYK,RGL1,GNAI2,FCHO2,PSAP,SH2B3,FYB1,SLC13A1,RAPGEF6,PTPN6,ITM2B,CSF1R,ADAM28,NTRK1,ENTPD1,ARAP1,DCC,RPL36A,CD74,ELMO1,ITGAX |
1.685e-02 | -4.08 | protein localization to plasma membrane | biological process | GO:0072659 | 197 | 3 | 18204 | 50 |
FYB1,RAPGEF6,FCHO2 |
1.685e-02 | -4.08 | negative regulation of immune response | biological process | GO:0050777 | 197 | 3 | 18204 | 50 |
HCK,SYK,PTPN6 |
1.687e-02 | -4.08 | DUF1041 | smart domains | SM01145 | 5 | 1 | 9717 | 33 |
CADPS2 |
1.696e-02 | -4.08 | EPHB2 (EPH receptor B2) | protein interactions | 2048 | 211 | 3 | 19454 | 50 |
CSF1R,FCHO2,GAB1 |
1.696e-02 | -4.08 | CCDC88A (coiled-coil domain containing 88A) | protein interactions | 55704 | 211 | 3 | 19454 | 50 |
GNAI2,NTRK1,PTPN6 |
1.696e-02 | -4.08 | CTR9 (CTR9 homolog, Paf1/RNA polymerase II complex component) | protein interactions | 9646 | 211 | 3 | 19454 | 50 |
RPL12,NTRK1,PTPN6 |
1.709e-02 | -4.07 | human chr12q24.12 | chromosome location | human chr12q24.12 | 9 | 1 | 26134 | 50 |
SH2B3 |
1.717e-02 | -4.06 | CSTPP1 (centriolar satellite-associated tubulin polyglutamylase complex regulator 1) | protein interactions | 79096 | 78 | 2 | 19454 | 50 |
RPL8,RPS3A |
1.717e-02 | -4.06 | regulation of multicellular organismal process | biological process | GO:0051239 | 3113 | 15 | 18204 | 50 |
PTPN6,GNAI2,DCC,HIPK2,SH2B3,RBM47,GAB1,SYK,CD74,RXRA,ITGAX,CARD10,NTRK1,CSF1R,BMP2K |
1.718e-02 | -4.06 | EPS15 (epidermal growth factor receptor pathway substrate 15) | protein interactions | 2060 | 212 | 3 | 19454 | 50 |
BMP2K,FCHO2,NTRK1 |
1.718e-02 | -4.06 | ZC3H7A (zinc finger CCCH-type containing 7A) | protein interactions | 29066 | 212 | 3 | 19454 | 50 |
NTRK1,RPS20,RBM47 |
1.721e-02 | -4.06 | skin-ankle-malignant_melanoma | COSMIC cancer mutations | skin-ankle-malignant_melanoma | 69 | 2 | 16828 | 49 |
ADAM28,DCC |
1.722e-02 | -4.06 | regulation of signal transduction | biological process | GO:0009966 | 3114 | 15 | 18204 | 50 |
RPS20,HIPK2,RBM47,SH2B3,PTPN6,GNAI2,NTRK1,BMP2K,CSF1R,ARAP1,IVNS1ABP,CTSS,SYK,CD74,RXRA |
1.729e-02 | -4.06 | RNF123 (ring finger protein 123) | protein interactions | 63891 | 812 | 6 | 19454 | 50 |
RPS25,RPS20,RPS14,RPS26,RPL12,IVNS1ABP |
1.731e-02 | -4.06 | regulation of developmental process | biological process | GO:0050793 | 2540 | 13 | 18204 | 50 |
HIPK2,DCC,HCK,PTPN6,ARAP1,CSF1R,BMP2K,NTRK1,CD74,RXRA,ITGAX,GAB1,SYK |
1.739e-02 | -4.05 | LMNB1 (lamin B1) | protein interactions | 4001 | 590 | 5 | 19454 | 50 |
RPL36A,PDE6D,NTRK1,RXRA,GNAI2 |
1.739e-02 | -4.05 | PPP6C (protein phosphatase 6 catalytic subunit) | protein interactions | 5537 | 213 | 3 | 19454 | 50 |
NTRK1,RPL27A,RPL8 |
1.739e-02 | -4.05 | SIAH1 (siah E3 ubiquitin protein ligase 1) | protein interactions | 6477 | 213 | 3 | 19454 | 50 |
RPL27A,DCC,HIPK2 |
1.750e-02 | -4.05 | positive regulation of protein modification process | biological process | GO:0031401 | 762 | 6 | 18204 | 50 |
SYK,CD74,CARD10,NTRK1,CSF1R,HIPK2 |
1.758e-02 | -4.04 | mononuclear cell differentiation | biological process | GO:1903131 | 364 | 4 | 18204 | 50 |
NTRK1,SYK,CSF1R,CD74 |
1.759e-02 | -4.04 | IRF2BP1 (interferon regulatory factor 2 binding protein 1) | protein interactions | 26145 | 79 | 2 | 19454 | 50 |
PDE6D,NTRK1 |
1.759e-02 | -4.04 | ZNF2 (zinc finger protein 2) | protein interactions | 7549 | 79 | 2 | 19454 | 50 |
RPS3A,RPL37A |
1.759e-02 | -4.04 | PALS2 (protein associated with LIN7 2, MAGUK p55 family member) | protein interactions | 51678 | 79 | 2 | 19454 | 50 |
RPS20,NTRK1 |
1.759e-02 | -4.04 | ZNF526 (zinc finger protein 526) | protein interactions | 116115 | 79 | 2 | 19454 | 50 |
RPL27A,RPL14 |
1.761e-02 | -4.04 | AP1B1 (adaptor related protein complex 1 subunit beta 1) | protein interactions | 162 | 214 | 3 | 19454 | 50 |
BMP2K,FCHO2,NTRK1 |
1.761e-02 | -4.04 | MRPL23 (mitochondrial ribosomal protein L23) | protein interactions | 6150 | 214 | 3 | 19454 | 50 |
RPL8,RPS3A,RPS20 |
1.761e-02 | -4.04 | GNAI3 (G protein subunit alpha i3) | protein interactions | 2773 | 214 | 3 | 19454 | 50 |
GNAI2,GAB1,NTRK1 |
1.761e-02 | -4.04 | CEP76 (centrosomal protein 76) | protein interactions | 79959 | 214 | 3 | 19454 | 50 |
RPS14,RPS25,RPS3A |
1.761e-02 | -4.04 | NCAPD2 (non-SMC condensin I complex subunit D2) | protein interactions | 9918 | 214 | 3 | 19454 | 50 |
IVNS1ABP,CD74,NTRK1 |
1.774e-02 | -4.03 | FLNA (filamin A) | protein interactions | 2316 | 593 | 5 | 19454 | 50 |
BMP2K,SPECC1,SYK,NTRK1,SH2B3 |
1.774e-02 | -4.03 | Signaling events mediated by TCPTP | Pathway Interaction DB | tcptp_pathway | 36 | 2 | 2226 | 13 |
GAB1,CSF1R |
1.777e-02 | -4.03 | negative regulation of inflammatory response | biological process | GO:0050728 | 201 | 3 | 18204 | 50 |
HCK,PTPN6,SYK |
1.782e-02 | -4.03 | DNAJC11 (DnaJ heat shock protein family (Hsp40) member C11) | protein interactions | 55735 | 215 | 3 | 19454 | 50 |
RPL18A,PDE6D,NTRK1 |
1.786e-02 | -4.03 | ZNF366 (zinc finger protein 366) | protein interactions | 167465 | 7 | 1 | 19454 | 50 |
CARD10 |
1.786e-02 | -4.03 | NSUN7 (NOP2/Sun RNA methyltransferase family member 7) | protein interactions | 79730 | 7 | 1 | 19454 | 50 |
PTPN6 |
1.786e-02 | -4.03 | CFAP47 (cilia and flagella associated protein 47) | protein interactions | 286464 | 7 | 1 | 19454 | 50 |
RPL35 |
1.786e-02 | -4.03 | ZNF180 (zinc finger protein 180) | protein interactions | 7733 | 7 | 1 | 19454 | 50 |
CARD10 |
1.786e-02 | -4.03 | Gadd45b (growth arrest and DNA-damage-inducible 45 beta) | protein interactions | 17873 | 7 | 1 | 19454 | 50 |
RXRA |
1.786e-02 | -4.03 | ZCCHC24 (zinc finger CCHC-type containing 24) | protein interactions | 219654 | 7 | 1 | 19454 | 50 |
RBM47 |
1.786e-02 | -4.03 | LAIR1 (leukocyte associated immunoglobulin like receptor 1) | protein interactions | 3903 | 7 | 1 | 19454 | 50 |
PTPN6 |
1.786e-02 | -4.03 | C7 (complement C7) | protein interactions | 730 | 7 | 1 | 19454 | 50 |
NTRK1 |
1.786e-02 | -4.03 | Dlg4 (discs large MAGUK scaffold protein 4) | protein interactions | 29495 | 7 | 1 | 19454 | 50 |
PDZRN3 |
1.786e-02 | -4.03 | RTL1 (retrotransposon Gag like 1) | protein interactions | 388015 | 7 | 1 | 19454 | 50 |
NTRK1 |
1.786e-02 | -4.03 | RGS18 (regulator of G protein signaling 18) | protein interactions | 64407 | 7 | 1 | 19454 | 50 |
GNAI2 |
1.786e-02 | -4.03 | SIGLEC9 (sialic acid binding Ig like lectin 9) | protein interactions | 27180 | 7 | 1 | 19454 | 50 |
PTPN6 |
1.801e-02 | -4.02 | positive regulation of cell population proliferation | biological process | GO:0008284 | 992 | 7 | 18204 | 50 |
HCK,ITGAX,CD74,GNAI2,PTPN6,CSF1R,HIPK2 |
1.806e-02 | -4.01 | adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway | biological process | GO:0007193 | 75 | 2 | 18204 | 50 |
PSAP,GNAI2 |
1.819e-02 | -4.01 | regulation of phosphorylation | biological process | GO:0042325 | 994 | 7 | 18204 | 50 |
HIPK2,CSF1R,CARD10,NTRK1,CD74,PTPN6,SYK |
1.824e-02 | -4.00 | negative regulation of cell-cell adhesion | biological process | GO:0022408 | 203 | 3 | 18204 | 50 |
PTPN6,CD74,SH2B3 |
1.827e-02 | -4.00 | Tuberculosis | KEGG pathways | hsa05152 | 178 | 4 | 7161 | 41 |
CD74,SYK,ITGAX,CTSS |
1.827e-02 | -4.00 | Tuberculosis | KEGG pathways | ko05152 | 178 | 4 | 7161 | 41 |
CD74,SYK,ITGAX,CTSS |
1.843e-02 | -3.99 | PEX6 (peroxisomal biogenesis factor 6) | protein interactions | 5190 | 81 | 2 | 19454 | 50 |
RPL27A,RPS14 |
1.843e-02 | -3.99 | DNAJC5B (DnaJ heat shock protein family (Hsp40) member C5 beta) | protein interactions | 85479 | 81 | 2 | 19454 | 50 |
RPL34,RPL18A |
1.849e-02 | -3.99 | MIA3 (MIA SH3 domain ER export factor 3) | protein interactions | 375056 | 218 | 3 | 19454 | 50 |
NTRK1,ITGAX,CTSS |
1.861e-02 | -3.98 | Transcriptional misregulation in cancer | KEGG pathways | hsa05202 | 179 | 4 | 7161 | 41 |
CSF1R,BMP2K,RXRA,NTRK1 |
1.861e-02 | -3.98 | Transcriptional misregulation in cancer | KEGG pathways | ko05202 | 179 | 4 | 7161 | 41 |
RXRA,NTRK1,CSF1R,BMP2K |
1.866e-02 | -3.98 | EIF4G1 (eukaryotic translation initiation factor 4 gamma 1) | protein interactions | 1981 | 396 | 4 | 19454 | 50 |
RPS25,CD74,NTRK1,RPL35 |
1.866e-02 | -3.98 | IPO5 (importin 5) | protein interactions | 3843 | 396 | 4 | 19454 | 50 |
RPL35,NTRK1,RPL27A,RPS20 |
1.872e-02 | -3.98 | regulation of DNA-binding transcription factor activity | biological process | GO:0051090 | 371 | 4 | 18204 | 50 |
NTRK1,SYK,HCK,HIPK2 |
1.875e-02 | -3.98 | Munc13_1 | interpro domains | IPR014770 | 7 | 1 | 18521 | 50 |
CADPS2 |
1.875e-02 | -3.98 | Prot_inhib_I29 | interpro domains | IPR013201 | 7 | 1 | 18521 | 50 |
CTSS |
1.875e-02 | -3.98 | Glyco_hydro_47 | interpro domains | IPR001382 | 7 | 1 | 18521 | 50 |
MAN1C1 |
1.875e-02 | -3.98 | Seven-hairpin_glycosidases | interpro domains | IPR036026 | 7 | 1 | 18521 | 50 |
MAN1C1 |
1.875e-02 | -3.98 | MUN_dom | interpro domains | IPR010439 | 7 | 1 | 18521 | 50 |
CADPS2 |
1.875e-02 | -3.98 | SaposinB_dom | interpro domains | IPR008139 | 7 | 1 | 18521 | 50 |
PSAP |
1.881e-02 | -3.97 | LBD domain binding | molecular function | GO:0050693 | 7 | 1 | 18094 | 49 |
RXRA |
1.881e-02 | -3.97 | MHC class II protein binding | molecular function | GO:0042289 | 7 | 1 | 18094 | 49 |
CD74 |
1.881e-02 | -3.97 | mannosyl-oligosaccharide 1,2-alpha-mannosidase activity | molecular function | GO:0004571 | 7 | 1 | 18094 | 49 |
MAN1C1 |
1.881e-02 | -3.97 | HDAC4 (histone deacetylase 4) | protein interactions | 9759 | 397 | 4 | 19454 | 50 |
SYK,RPS14,RPS3A,RXRA |
1.886e-02 | -3.97 | MAP4K3 (mitogen-activated protein kinase kinase kinase kinase 3) | protein interactions | 8491 | 82 | 2 | 19454 | 50 |
NTRK1,RPL37A |
1.886e-02 | -3.97 | TUBA8 (tubulin alpha 8) | protein interactions | 51807 | 82 | 2 | 19454 | 50 |
RPL8,RPL37A |
1.893e-02 | -3.97 | MRPL13 (mitochondrial ribosomal protein L13) | protein interactions | 28998 | 220 | 3 | 19454 | 50 |
RPL35,RPL27A,RPL13A |
1.900e-02 | -3.96 | lung-carcinoma-undifferentiated_carcinoma | COSMIC cancer mutations | lung-carcinoma-undifferentiated_carcinoma | 1408 | 9 | 16828 | 49 |
SYK,RGL1,CARD10,CSF1R,SPECC1,GAB1,PTPN6,RAPGEF6,NTRK1 |
1.902e-02 | -3.96 | testis | COSMIC cancer mutations | testis | 733 | 6 | 16828 | 49 |
CSF1R,HCK,NTRK1,BMP2K,HIPK2,SYK |
1.902e-02 | -3.96 | regulation of protein modification process | biological process | GO:0031399 | 1242 | 8 | 18204 | 50 |
SYK,PTPN6,CD74,NTRK1,CARD10,IVNS1ABP,CSF1R,HIPK2 |
1.907e-02 | -3.96 | ubiquitin-dependent glycoprotein ERAD pathway | biological process | GO:0097466 | 7 | 1 | 18204 | 50 |
MAN1C1 |
1.907e-02 | -3.96 | platelet degranulation | biological process | GO:0002576 | 7 | 1 | 18204 | 50 |
SYK |
1.907e-02 | -3.96 | regulation of arachidonic acid secretion | biological process | GO:0090237 | 7 | 1 | 18204 | 50 |
SYK |
1.907e-02 | -3.96 | dense core granule exocytosis | biological process | GO:1990504 | 7 | 1 | 18204 | 50 |
CADPS2 |
1.907e-02 | -3.96 | interleukin-3-mediated signaling pathway | biological process | GO:0038156 | 7 | 1 | 18204 | 50 |
SYK |
1.907e-02 | -3.96 | mannose trimming involved in glycoprotein ERAD pathway | biological process | GO:1904382 | 7 | 1 | 18204 | 50 |
MAN1C1 |
1.907e-02 | -3.96 | protein alpha-1,2-demannosylation | biological process | GO:0036508 | 7 | 1 | 18204 | 50 |
MAN1C1 |
1.907e-02 | -3.96 | cellular response to interleukin-3 | biological process | GO:0036016 | 7 | 1 | 18204 | 50 |
SH2B3 |
1.907e-02 | -3.96 | PML body organization | biological process | GO:0030578 | 7 | 1 | 18204 | 50 |
HIPK2 |
1.907e-02 | -3.96 | protein demannosylation | biological process | GO:0036507 | 7 | 1 | 18204 | 50 |
MAN1C1 |
1.907e-02 | -3.96 | olfactory nerve development | biological process | GO:0021553 | 7 | 1 | 18204 | 50 |
NTRK1 |
1.907e-02 | -3.96 | response to interleukin-3 | biological process | GO:0036015 | 7 | 1 | 18204 | 50 |
SH2B3 |
1.907e-02 | -3.96 | anterior/posterior axon guidance | biological process | GO:0033564 | 7 | 1 | 18204 | 50 |
DCC |
1.907e-02 | -3.96 | regulation of macrophage proliferation | biological process | GO:0120040 | 7 | 1 | 18204 | 50 |
CSF1R |
1.907e-02 | -3.96 | protein deglycosylation involved in glycoprotein catabolic process | biological process | GO:0035977 | 7 | 1 | 18204 | 50 |
MAN1C1 |
1.907e-02 | -3.96 | response to hydrostatic pressure | biological process | GO:0051599 | 7 | 1 | 18204 | 50 |
NTRK1 |
1.907e-02 | -3.96 | positive regulation of gamma-delta T cell differentiation | biological process | GO:0045588 | 7 | 1 | 18204 | 50 |
SYK |
1.907e-02 | -3.96 | positive regulation of dendritic cell antigen processing and presentation | biological process | GO:0002606 | 7 | 1 | 18204 | 50 |
CD74 |
1.907e-02 | -3.96 | voluntary musculoskeletal movement | biological process | GO:0050882 | 7 | 1 | 18204 | 50 |
HIPK2 |
1.907e-02 | -3.96 | regulation of thyroid hormone mediated signaling pathway | biological process | GO:0002155 | 7 | 1 | 18204 | 50 |
RXRA |
1.916e-02 | -3.95 | RPS6KA1 (ribosomal protein S6 kinase A1) | protein interactions | 6195 | 221 | 3 | 19454 | 50 |
NTRK1,PDZRN3,SYK |
1.916e-02 | -3.95 | OASL (2'-5'-oligoadenylate synthetase like) | protein interactions | 8638 | 221 | 3 | 19454 | 50 |
RPL14,RPL35,RPS3A |
1.930e-02 | -3.95 | DDX60 (DExD/H-box helicase 60) | protein interactions | 55601 | 83 | 2 | 19454 | 50 |
CD74,RPL36A |
1.930e-02 | -3.95 | WDR70 (WD repeat domain 70) | protein interactions | 55100 | 83 | 2 | 19454 | 50 |
RPL36A,NTRK1 |
1.930e-02 | -3.95 | defense response to other organism | biological process | GO:0098542 | 1006 | 7 | 18204 | 50 |
RPL13A,SYK,PTPN6,ITGAX,HCK,CD74,CSF1R |
1.933e-02 | -3.95 | - | gene3d domains | 3.10.20.10 | 6 | 1 | 14470 | 47 |
RPL18A |
1.939e-02 | -3.94 | PURG (purine rich element binding protein G) | protein interactions | 29942 | 222 | 3 | 19454 | 50 |
RPL37A,RPS14,RPS3A |
1.941e-02 | -3.94 | DDX3X (DEAD-box helicase 3 X-linked) | protein interactions | 1654 | 607 | 5 | 19454 | 50 |
RPS3A,NTRK1,RPS25,RPS20,RPS14 |
1.947e-02 | -3.94 | GPVI-mediated activation cascade | REACTOME pathways | R-HSA-114604 | 54 | 2 | 10285 | 41 |
SYK,PTPN6 |
1.951e-02 | -3.94 | Glyco_hydro_47 | pfam domains | PF01532 | 7 | 1 | 17795 | 50 |
MAN1C1 |
1.951e-02 | -3.94 | MUN | pfam domains | PF06292 | 7 | 1 | 17795 | 50 |
CADPS2 |
1.951e-02 | -3.94 | Inhibitor_I29 | pfam domains | PF08246 | 7 | 1 | 17795 | 50 |
CTSS |
1.958e-02 | -3.93 | skin-shoulder-malignant_melanoma | COSMIC cancer mutations | skin-shoulder-malignant_melanoma | 355 | 4 | 16828 | 49 |
NTRK1,ARAP1,ADAM28,DCC |
1.978e-02 | -3.92 | MET activates PTPN11 | REACTOME pathways | R-HSA-8865999 | 5 | 1 | 10285 | 41 |
GAB1 |
1.978e-02 | -3.92 | Sodium-coupled sulphate, di- and tri-carboxylate transporters | REACTOME pathways | R-HSA-433137 | 5 | 1 | 10285 | 41 |
SLC13A1 |
1.978e-02 | -3.92 | NGF-independant TRKA activation | REACTOME pathways | R-HSA-187024 | 5 | 1 | 10285 | 41 |
NTRK1 |
1.978e-02 | -3.92 | N-glycan trimming and elongation in the cis-Golgi | REACTOME pathways | R-HSA-964739 | 5 | 1 | 10285 | 41 |
MAN1C1 |
1.981e-02 | -3.92 | undifferentiated_carcinoma | COSMIC cancer mutations | undifferentiated_carcinoma | 1418 | 9 | 16828 | 49 |
RAPGEF6,NTRK1,GAB1,PTPN6,CARD10,RGL1,CSF1R,SPECC1,SYK |
1.985e-02 | -3.92 | ZC3H3 (zinc finger CCCH-type containing 3) | protein interactions | 23144 | 224 | 3 | 19454 | 50 |
RPL18A,RPS3A,RPL13A |
1.989e-02 | -3.92 | plasma membrane protein complex | cellular component | GO:0098797 | 600 | 5 | 19108 | 50 |
ITGAX,PTPN6,GNAI2,SYK,CD74 |
1.991e-02 | -3.92 | myeloid cell development | biological process | GO:0061515 | 79 | 2 | 18204 | 50 |
SH2B3,PTPN6 |
1.991e-02 | -3.92 | FGFR1 (fibroblast growth factor receptor 1) | protein interactions | 2260 | 611 | 5 | 19454 | 50 |
RXRA,ITM2B,BMP2K,FCHO2,GAB1 |
1.996e-02 | -3.91 | caveola | cellular component | GO:0005901 | 83 | 2 | 19108 | 50 |
ENTPD1,HCK |
2.018e-02 | -3.90 | ABRAXAS2 (abraxas 2, BRISC complex subunit) | protein interactions | 23172 | 85 | 2 | 19454 | 50 |
SH2B3,SYK |
2.018e-02 | -3.90 | ZAP70 (zeta chain of T cell receptor associated protein kinase 70) | protein interactions | 7535 | 85 | 2 | 19454 | 50 |
PTPN6,SH2B3 |
2.018e-02 | -3.90 | WSB2 (WD repeat and SOCS box containing 2) | protein interactions | 55884 | 85 | 2 | 19454 | 50 |
RPL13A,RPS14 |
2.018e-02 | -3.90 | positive regulation of GTPase activity | biological process | GO:0043547 | 211 | 3 | 18204 | 50 |
ARAP1,RAPGEF6,NTRK1 |
2.021e-02 | -3.90 | SapB | smart domains | SM00741 | 6 | 1 | 9717 | 33 |
PSAP |
2.032e-02 | -3.90 | transmembrane receptor protein kinase activity | molecular function | GO:0019199 | 81 | 2 | 18094 | 49 |
CSF1R,NTRK1 |
2.038e-02 | -3.89 | CD1D (CD1d molecule) | protein interactions | 912 | 8 | 1 | 19454 | 50 |
CD74 |
2.038e-02 | -3.89 | ZNF239 (zinc finger protein 239) | protein interactions | 8187 | 8 | 1 | 19454 | 50 |
CARD10 |
2.038e-02 | -3.89 | ISLR2 (immunoglobulin superfamily containing leucine rich repeat 2) | protein interactions | 57611 | 8 | 1 | 19454 | 50 |
NTRK1 |
2.038e-02 | -3.89 | PHOX2A (paired like homeobox 2A) | protein interactions | 401 | 8 | 1 | 19454 | 50 |
NTRK1 |
2.038e-02 | -3.89 | EIF4E3 (eukaryotic translation initiation factor 4E family member 3) | protein interactions | 317649 | 8 | 1 | 19454 | 50 |
DCC |
2.038e-02 | -3.89 | LILRB1 (leukocyte immunoglobulin like receptor B1) | protein interactions | 10859 | 8 | 1 | 19454 | 50 |
PTPN6 |
2.038e-02 | -3.89 | KCNK4 (potassium two pore domain channel subfamily K member 4) | protein interactions | 50801 | 8 | 1 | 19454 | 50 |
RPL14 |
2.038e-02 | -3.89 | TREML1 (triggering receptor expressed on myeloid cells like 1) | protein interactions | 340205 | 8 | 1 | 19454 | 50 |
PTPN6 |
2.038e-02 | -3.89 | PEX5L (peroxisomal biogenesis factor 5 like) | protein interactions | 51555 | 8 | 1 | 19454 | 50 |
RPS25 |
2.038e-02 | -3.89 | CXCR5 (C-X-C motif chemokine receptor 5) | protein interactions | 643 | 8 | 1 | 19454 | 50 |
GNAI2 |
2.038e-02 | -3.89 | LHB (luteinizing hormone subunit beta) | protein interactions | 3972 | 8 | 1 | 19454 | 50 |
GNAI2 |
2.038e-02 | -3.89 | DISP3 (dispatched RND transporter family member 3) | protein interactions | 57540 | 8 | 1 | 19454 | 50 |
RPS14 |
2.038e-02 | -3.89 | LINC01232 (long intergenic non-protein coding RNA 1232) | protein interactions | 102725509 | 8 | 1 | 19454 | 50 |
RPS3A |
2.038e-02 | -3.89 | NBPF1 (NBPF member 1) | protein interactions | 55672 | 8 | 1 | 19454 | 50 |
RPL27A |
2.038e-02 | -3.89 | ZNF415 (zinc finger protein 415) | protein interactions | 55786 | 8 | 1 | 19454 | 50 |
CARD10 |
2.040e-02 | -3.89 | THRAP3 (thyroid hormone receptor associated protein 3) | protein interactions | 9967 | 407 | 4 | 19454 | 50 |
IVNS1ABP,PSAP,RPS3A,NTRK1 |
2.042e-02 | -3.89 | UBE2I (ubiquitin conjugating enzyme E2 I) | protein interactions | 7329 | 615 | 5 | 19454 | 50 |
FYB1,HIPK2,RPL8,RXRA,RPS3A |
2.042e-02 | -3.89 | RAC3 (Rac family small GTPase 3) | protein interactions | 5881 | 615 | 5 | 19454 | 50 |
DIAPH2,ITM2B,FCHO2,GAB1,SPECC1 |
2.042e-02 | -3.89 | positive regulation of transferase activity | biological process | GO:0051347 | 381 | 4 | 18204 | 50 |
NTRK1,CARD10,CSF1R,CD74 |
2.063e-02 | -3.88 | WAS (WASP actin nucleation promoting factor) | protein interactions | 7454 | 86 | 2 | 19454 | 50 |
HCK,FYB1 |
2.069e-02 | -3.88 | protein binding | molecular function | GO:0005515 | 13983 | 44 | 18094 | 49 |
ADAM28,SH2B3,PSAP,RPL12,CTSS,RAPGEF6,IVNS1ABP,CSF1R,RBM47,RPS3A,HIPK2,RXRA,RPS14,PDE6D,ITM2B,GNAI2,FCHO2,CD74,RPL8,DCC,RPL36A,RPL34,PTPN6,ITGAX,HCK,RPS26,CARD10,ELMO1,MAN1C1,RPL14,RPS25,SYK,DIAPH2,RPS20,RPL18A,RPL37A,FYB1,RGL1,BMP2K,NTRK1,RPL27A,ARAP1,GAB1,ENTPD1 |
2.073e-02 | -3.88 | LIMA1 (LIM domain and actin binding 1) | protein interactions | 51474 | 409 | 4 | 19454 | 50 |
NTRK1,BMP2K,FCHO2,SPECC1 |
2.075e-02 | -3.88 | presynaptic endocytic zone membrane | cellular component | GO:0098835 | 8 | 1 | 19108 | 50 |
FCHO2 |
2.079e-02 | -3.87 | H2AC17 (H2A clustered histone 17) | protein interactions | 8336 | 228 | 3 | 19454 | 50 |
RPS3A,RPS20,RPS14 |
2.079e-02 | -3.87 | receptor tyrosine kinase binding | molecular function | GO:0030971 | 82 | 2 | 18094 | 49 |
SH2B3,ITGAX |
2.087e-02 | -3.87 | positive regulation of cytokine production involved in immune response | biological process | GO:0002720 | 81 | 2 | 18204 | 50 |
SYK,CD74 |
2.087e-02 | -3.87 | Ras protein signal transduction | biological process | GO:0007265 | 81 | 2 | 18204 | 50 |
RGL1,RAPGEF6 |
2.094e-02 | -3.87 | negative regulation of cell activation | biological process | GO:0050866 | 214 | 3 | 18204 | 50 |
SH2B3,CD74,PTPN6 |
2.108e-02 | -3.86 | FGR (FGR proto-oncogene, Src family tyrosine kinase) | protein interactions | 2268 | 87 | 2 | 19454 | 50 |
HCK,SYK |
2.108e-02 | -3.86 | TAF1B (TATA-box binding protein associated factor, RNA polymerase I subunit B) | protein interactions | 9014 | 87 | 2 | 19454 | 50 |
RXRA,RPL13A |
2.108e-02 | -3.86 | CERK (ceramide kinase) | protein interactions | 64781 | 87 | 2 | 19454 | 50 |
NTRK1,RPS14 |
2.108e-02 | -3.86 | NKTR (natural killer cell triggering receptor) | protein interactions | 4820 | 87 | 2 | 19454 | 50 |
RPS14,RPL13A |
2.119e-02 | -3.85 | IL-6 signaling pathway | WikiPathways | WP364 | 43 | 2 | 5310 | 28 |
HCK,GAB1 |
2.126e-02 | -3.85 | skin-leg-malignant_melanoma | COSMIC cancer mutations | skin-leg-malignant_melanoma | 549 | 5 | 16828 | 49 |
HCK,NTRK1,RPS14,DCC,DIAPH2 |
2.127e-02 | -3.85 | VARS1 (valyl-tRNA synthetase 1) | protein interactions | 7407 | 230 | 3 | 19454 | 50 |
RPS3A,NTRK1,PTPN6 |
2.128e-02 | -3.85 | mesothelioma | COSMIC cancer mutations | mesothelioma | 4477 | 20 | 16828 | 49 |
GAB1,HIPK2,CTSS,NTRK1,RAPGEF6,ITGAX,DIAPH2,HCK,SPECC1,ADAM28,PTPN6,PDZRN3,RPL36A,SYK,BMP2K,GNAI2,CSF1R,SH2B3,RGL1,CARD10 |
2.135e-02 | -3.85 | regulation of bone mineralization | biological process | GO:0030500 | 82 | 2 | 18204 | 50 |
RXRA,BMP2K |
2.135e-02 | -3.85 | cellular response to type II interferon | biological process | GO:0071346 | 82 | 2 | 18204 | 50 |
RPL13A,HCK |
2.140e-02 | -3.84 | Peptidase_C1A_papain-like | interpro domains | IPR039417 | 8 | 1 | 18521 | 50 |
CTSS |
2.140e-02 | -3.84 | Tyr_kinase_rcpt_3_CS | interpro domains | IPR001824 | 8 | 1 | 18521 | 50 |
CSF1R |
2.140e-02 | -3.84 | Gprotein_alpha_I | interpro domains | IPR001408 | 8 | 1 | 18521 | 50 |
GNAI2 |
2.140e-02 | -3.84 | GDA1_CD39_NTPase | interpro domains | IPR000407 | 8 | 1 | 18521 | 50 |
ENTPD1 |
2.140e-02 | -3.84 | DAD_dom | interpro domains | IPR014767 | 8 | 1 | 18521 | 50 |
DIAPH2 |
2.146e-02 | -3.84 | cell chemotaxis | biological process | GO:0060326 | 216 | 3 | 18204 | 50 |
GAB1,RPL13A,SYK |
2.146e-02 | -3.84 | regulation of lymphocyte differentiation | biological process | GO:0045619 | 216 | 3 | 18204 | 50 |
CD74,SYK,PTPN6 |
2.146e-02 | -3.84 | U2AF2 (U2 small nuclear RNA auxiliary factor 2) | protein interactions | 11338 | 623 | 5 | 19454 | 50 |
GNAI2,RPL37A,RPL18A,RPS3A,NTRK1 |
2.146e-02 | -3.84 | ubiquitin ligase inhibitor activity | molecular function | GO:1990948 | 8 | 1 | 18094 | 49 |
RPS20 |
2.146e-02 | -3.84 | phosphorylation-dependent protein binding | molecular function | GO:0140031 | 8 | 1 | 18094 | 49 |
PTPN6 |
2.146e-02 | -3.84 | CD4 receptor binding | molecular function | GO:0042609 | 8 | 1 | 18094 | 49 |
CD74 |
2.147e-02 | -3.84 | ELMO | prosite domains | PS51335 | 6 | 1 | 12186 | 44 |
ELMO1 |
2.153e-02 | -3.84 | PIK3CB (phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta) | protein interactions | 5291 | 88 | 2 | 19454 | 50 |
NTRK1,HCK |
2.153e-02 | -3.84 | RAP2A (RAP2A, member of RAS oncogene family) | protein interactions | 5911 | 88 | 2 | 19454 | 50 |
RAPGEF6,RGL1 |
2.153e-02 | -3.84 | RNMT (RNA guanine-7 methyltransferase) | protein interactions | 8731 | 88 | 2 | 19454 | 50 |
NTRK1,RXRA |
2.159e-02 | -3.84 | CSK (C-terminal Src kinase) | protein interactions | 1445 | 854 | 6 | 19454 | 50 |
GAB1,HCK,ELMO1,ADAM28,PDZRN3,IVNS1ABP |
2.175e-02 | -3.83 | BCR (BCR activator of RhoGEF and GTPase) | protein interactions | 613 | 232 | 3 | 19454 | 50 |
PTPN6,NTRK1,HCK |
2.175e-02 | -3.83 | MRPS11 (mitochondrial ribosomal protein S11) | protein interactions | 64963 | 232 | 3 | 19454 | 50 |
RPS26,RBM47,RPL35 |
2.175e-02 | -3.83 | CTSB (cathepsin B) | protein interactions | 1508 | 232 | 3 | 19454 | 50 |
CTSS,NTRK1,PSAP |
2.177e-02 | -3.83 | regulation of cytoplasmic translational initiation | biological process | GO:1904688 | 8 | 1 | 18204 | 50 |
RPL13A |
2.177e-02 | -3.83 | regulation of neutrophil degranulation | biological process | GO:0043313 | 8 | 1 | 18204 | 50 |
SYK |
2.177e-02 | -3.83 | glycolipid transport | biological process | GO:0046836 | 8 | 1 | 18204 | 50 |
PSAP |
2.177e-02 | -3.83 | negative regulation of dendrite development | biological process | GO:2000171 | 8 | 1 | 18204 | 50 |
DCC |
2.177e-02 | -3.83 | G protein-coupled adenosine receptor signaling pathway | biological process | GO:0001973 | 8 | 1 | 18204 | 50 |
GNAI2 |
2.177e-02 | -3.83 | cellular response to macrophage colony-stimulating factor stimulus | biological process | GO:0036006 | 8 | 1 | 18204 | 50 |
CSF1R |
2.177e-02 | -3.83 | positive regulation of killing of cells of another organism | biological process | GO:0051712 | 8 | 1 | 18204 | 50 |
SYK |
2.177e-02 | -3.83 | negative regulation of calcium ion-dependent exocytosis | biological process | GO:0045955 | 8 | 1 | 18204 | 50 |
GNAI2 |
2.177e-02 | -3.83 | positive regulation of unsaturated fatty acid biosynthetic process | biological process | GO:2001280 | 8 | 1 | 18204 | 50 |
CD74 |
2.177e-02 | -3.83 | G protein-coupled purinergic receptor signaling pathway | biological process | GO:0035588 | 8 | 1 | 18204 | 50 |
GNAI2 |
2.184e-02 | -3.82 | positive regulation of B cell activation | biological process | GO:0050871 | 83 | 2 | 18204 | 50 |
CD74,SYK |
2.185e-02 | -3.82 | immune effector process | biological process | GO:0002252 | 389 | 4 | 18204 | 50 |
SYK,PTPN6,HCK,CD74 |
2.199e-02 | -3.82 | BCL10 (BCL10 immune signaling adaptor) | protein interactions | 8915 | 89 | 2 | 19454 | 50 |
FYB1,CARD10 |
2.199e-02 | -3.82 | KLF9 (KLF transcription factor 9) | protein interactions | 687 | 89 | 2 | 19454 | 50 |
RPL36A,RPL34 |
2.200e-02 | -3.82 | EIF3I (eukaryotic translation initiation factor 3 subunit I) | protein interactions | 8668 | 233 | 3 | 19454 | 50 |
RPL37A,NTRK1,CD74 |
2.214e-02 | -3.81 | cell periphery | cellular component | GO:0071944 | 6020 | 23 | 19108 | 50 |
SLC13A1,RAPGEF6,FYB1,SH2B3,PSAP,FCHO2,GNAI2,RGL1,SYK,HCK,ITM2B,PTPN6,ARAP1,ENTPD1,NTRK1,ADAM28,CTSS,CSF1R,ITGAX,ELMO1,CD74,DCC,RPL36A |
2.226e-02 | -3.80 | Integrin_alpha | pfam domains | PF00357 | 8 | 1 | 17795 | 50 |
ITGAX |
2.226e-02 | -3.80 | GDA1_CD39 | pfam domains | PF01150 | 8 | 1 | 17795 | 50 |
ENTPD1 |
2.246e-02 | -3.80 | MBD6 (methyl-CpG binding domain protein 6) | protein interactions | 114785 | 90 | 2 | 19454 | 50 |
RPS25,RPS3A |
2.246e-02 | -3.80 | IPO13 (importin 13) | protein interactions | 9670 | 90 | 2 | 19454 | 50 |
CD74,NTRK1 |
2.246e-02 | -3.80 | SIAH2 (siah E3 ubiquitin protein ligase 2) | protein interactions | 6478 | 90 | 2 | 19454 | 50 |
HIPK2,DCC |
2.246e-02 | -3.80 | TAL1 (TAL bHLH transcription factor 1, erythroid differentiation factor) | protein interactions | 6886 | 90 | 2 | 19454 | 50 |
RPL13A,RPL34 |
2.246e-02 | -3.80 | DHX29 (DExH-box helicase 29) | protein interactions | 54505 | 90 | 2 | 19454 | 50 |
NTRK1,PTPN6 |
2.249e-02 | -3.79 | BLM (BLM RecQ like helicase) | protein interactions | 641 | 235 | 3 | 19454 | 50 |
RPL27A,RPL14,RPS14 |
2.274e-02 | -3.78 | positive regulation of cell migration | biological process | GO:0030335 | 592 | 5 | 18204 | 50 |
ITGAX,CSF1R,CD74,GNAI2,GAB1 |
2.277e-02 | -3.78 | leukocyte mediated immunity | biological process | GO:0002443 | 221 | 3 | 18204 | 50 |
SYK,PTPN6,CD74 |
2.277e-02 | -3.78 | KLF16 (KLF transcription factor 16) | protein interactions | 83855 | 421 | 4 | 19454 | 50 |
RPL13A,RPL36A,RPL18A,RPL37A |
2.290e-02 | -3.78 | Ecd (ecdysoneless cell cycle regulator) | protein interactions | 70601 | 9 | 1 | 19454 | 50 |
IVNS1ABP |
2.290e-02 | -3.78 | GAREM2 (GRB2 associated regulator of MAPK1 subtype 2) | protein interactions | 150946 | 9 | 1 | 19454 | 50 |
NTRK1 |
2.290e-02 | -3.78 | HLA-DMA (major histocompatibility complex, class II, DM alpha) | protein interactions | 3108 | 9 | 1 | 19454 | 50 |
CD74 |
2.290e-02 | -3.78 | RBM46 (RNA binding motif protein 46) | protein interactions | 166863 | 9 | 1 | 19454 | 50 |
RBM47 |
2.290e-02 | -3.78 | PEAR1 (platelet endothelial aggregation receptor 1) | protein interactions | 375033 | 9 | 1 | 19454 | 50 |
SYK |
2.290e-02 | -3.78 | RASA4 (RAS p21 protein activator 4) | protein interactions | 10156 | 9 | 1 | 19454 | 50 |
NTRK1 |
2.290e-02 | -3.78 | LILRB2 (leukocyte immunoglobulin like receptor B2) | protein interactions | 10288 | 9 | 1 | 19454 | 50 |
PTPN6 |
2.290e-02 | -3.78 | Recql4 (RecQ protein-like 4) | protein interactions | 79456 | 9 | 1 | 19454 | 50 |
GNAI2 |
2.290e-02 | -3.78 | NIM1K (NIM1 serine/threonine protein kinase) | protein interactions | 167359 | 9 | 1 | 19454 | 50 |
PDE6D |
2.290e-02 | -3.78 | PRRT4 (proline rich transmembrane protein 4) | protein interactions | 401399 | 9 | 1 | 19454 | 50 |
NTRK1 |
2.290e-02 | -3.78 | ADRA2B (adrenoceptor alpha 2B) | protein interactions | 151 | 9 | 1 | 19454 | 50 |
GNAI2 |
2.292e-02 | -3.78 | BRAT1 (BRCA1 associated ATM activator 1) | protein interactions | 221927 | 91 | 2 | 19454 | 50 |
GNAI2,NTRK1 |
2.292e-02 | -3.78 | ACVR1B (activin A receptor type 1B) | protein interactions | 91 | 91 | 2 | 19454 | 50 |
NTRK1,RXRA |
2.299e-02 | -3.77 | PPP6R3 (protein phosphatase 6 regulatory subunit 3) | protein interactions | 55291 | 237 | 3 | 19454 | 50 |
CD74,RPS25,NTRK1 |
2.306e-02 | -3.77 | haematopoietic_and_lymphoid_tissue-other-normal | COSMIC cancer mutations | haematopoietic_and_lymphoid_tissue-other-normal | 8 | 1 | 16828 | 49 |
CSF1R |
2.315e-02 | -3.77 | regulation of apoptotic signaling pathway | biological process | GO:2001233 | 396 | 4 | 18204 | 50 |
CD74,IVNS1ABP,CTSS,GNAI2 |
2.322e-02 | -3.76 | UBE2M (ubiquitin conjugating enzyme E2 M) | protein interactions | 9040 | 636 | 5 | 19454 | 50 |
RPL8,RPS14,IVNS1ABP,RPS20,RPS3A |
2.331e-02 | -3.76 | presynaptic endocytic zone | cellular component | GO:0098833 | 9 | 1 | 19108 | 50 |
FCHO2 |
2.332e-02 | -3.76 | extracellular region | cellular component | GO:0005576 | 4350 | 18 | 19108 | 50 |
ADAM28,CTSS,RPL34,MAN1C1,ENTPD1,RPS25,RPS14,CD74,RPS26,RPS3A,RPS20,RPL14,RPL37A,RPL12,PSAP,GNAI2,ITM2B,PTPN6 |
2.339e-02 | -3.76 | IRS2 (insulin receptor substrate 2) | protein interactions | 8660 | 92 | 2 | 19454 | 50 |
PTPN6,NTRK1 |
2.339e-02 | -3.76 | ORF50 (ORF50) | protein interactions | 4961526 | 92 | 2 | 19454 | 50 |
RPL36A,RPS3A |
2.339e-02 | -3.76 | RIC8A (RIC8 guanine nucleotide exchange factor A) | protein interactions | 60626 | 92 | 2 | 19454 | 50 |
GNAI2,NTRK1 |
2.354e-02 | -3.75 | Inhibitor_I29 | smart domains | SM00848 | 7 | 1 | 9717 | 33 |
CTSS |
2.358e-02 | -3.75 | neuron projection guidance | biological process | GO:0097485 | 224 | 3 | 18204 | 50 |
DCC,NTRK1,CSF1R |
2.358e-02 | -3.75 | axon guidance | biological process | GO:0007411 | 224 | 3 | 18204 | 50 |
DCC,NTRK1,CSF1R |
2.367e-02 | -3.74 | regulation of signaling | biological process | GO:0023051 | 3534 | 16 | 18204 | 50 |
GNAI2,PTPN6,SH2B3,RBM47,HIPK2,DCC,RPS20,RXRA,CD74,SYK,CTSS,IVNS1ABP,CSF1R,ARAP1,BMP2K,NTRK1 |
2.369e-02 | -3.74 | Activation of TRKA receptors | REACTOME pathways | R-HSA-187015 | 6 | 1 | 10285 | 41 |
NTRK1 |
2.369e-02 | -3.74 | MET activates PI3K/AKT signaling | REACTOME pathways | R-HSA-8851907 | 6 | 1 | 10285 | 41 |
GAB1 |
2.369e-02 | -3.74 | CD22 mediated BCR regulation | REACTOME pathways | R-HSA-5690714 | 6 | 1 | 10285 | 41 |
PTPN6 |
2.372e-02 | -3.74 | monocarboxylic acid binding | molecular function | GO:0033293 | 88 | 2 | 18094 | 49 |
RXRA,PSAP |
2.375e-02 | -3.74 | CDC27 (cell division cycle 27) | protein interactions | 996 | 240 | 3 | 19454 | 50 |
NTRK1,RPS14,ELMO1 |
2.375e-02 | -3.74 | MRPL42 (mitochondrial ribosomal protein L42) | protein interactions | 28977 | 240 | 3 | 19454 | 50 |
RPL27A,RBM47,RPL35 |
2.378e-02 | -3.74 | guanyl-nucleotide exchange factor activity | molecular function | GO:0005085 | 228 | 3 | 18094 | 49 |
RAPGEF6,ELMO1,RGL1 |
2.387e-02 | -3.74 | UTP25 (UTP25 small subunit processome component) | protein interactions | 27042 | 93 | 2 | 19454 | 50 |
NTRK1,BMP2K |
2.387e-02 | -3.74 | GLYHDRLASE47 | prints domains | PR00747 | 7 | 1 | 5227 | 18 |
MAN1C1 |
2.404e-02 | -3.73 | GTPase-bd | interpro domains | IPR010473 | 9 | 1 | 18521 | 50 |
DIAPH2 |
2.404e-02 | -3.73 | FH3_dom | interpro domains | IPR010472 | 9 | 1 | 18521 | 50 |
DIAPH2 |
2.404e-02 | -3.73 | BRICHOS_dom | interpro domains | IPR007084 | 9 | 1 | 18521 | 50 |
ITM2B |
2.406e-02 | -3.73 | EEF1A1 (eukaryotic translation elongation factor 1 alpha 1) | protein interactions | 1915 | 642 | 5 | 19454 | 50 |
RPS3A,NTRK1,RPL12,RPL18A,RPS14 |
2.408e-02 | -3.73 | regulation of cell communication | biological process | GO:0010646 | 3541 | 16 | 18204 | 50 |
RPS20,DCC,HIPK2,RBM47,SH2B3,PTPN6,GNAI2,NTRK1,BMP2K,ARAP1,CSF1R,IVNS1ABP,CTSS,SYK,CD74,RXRA |
2.412e-02 | -3.72 | UDP phosphatase activity | molecular function | GO:0045134 | 9 | 1 | 18094 | 49 |
ENTPD1 |
2.412e-02 | -3.72 | mannosyl-oligosaccharide mannosidase activity | molecular function | GO:0015924 | 9 | 1 | 18094 | 49 |
MAN1C1 |
2.412e-02 | -3.72 | angiotensin receptor binding | molecular function | GO:0031701 | 9 | 1 | 18094 | 49 |
ARAP1 |
2.422e-02 | -3.72 | amyloid-beta binding | molecular function | GO:0001540 | 89 | 2 | 18094 | 49 |
CD74,ITM2B |
2.427e-02 | -3.72 | PRRC2B (proline rich coiled-coil 2B) | protein interactions | 84726 | 242 | 3 | 19454 | 50 |
CD74,RPS20,RBM47 |
2.435e-02 | -3.72 | TOM1 (target of myb1 membrane trafficking protein) | protein interactions | 10043 | 94 | 2 | 19454 | 50 |
NTRK1,RPS20 |
2.435e-02 | -3.72 | HIPK2 (homeodomain interacting protein kinase 2) | protein interactions | 28996 | 94 | 2 | 19454 | 50 |
HIPK2,NTRK1 |
2.435e-02 | -3.72 | AFG2A (AFG2 AAA ATPase homolog A) | protein interactions | 166378 | 94 | 2 | 19454 | 50 |
SYK,NTRK1 |
2.436e-02 | -3.71 | regulation of tissue remodeling | biological process | GO:0034103 | 88 | 2 | 18204 | 50 |
SYK,CSF1R |
2.446e-02 | -3.71 | positive regulation of gamma-delta T cell activation | biological process | GO:0046645 | 9 | 1 | 18204 | 50 |
SYK |
2.446e-02 | -3.71 | regulation of killing of cells of another organism | biological process | GO:0051709 | 9 | 1 | 18204 | 50 |
SYK |
2.446e-02 | -3.71 | cellular response to nicotine | biological process | GO:0071316 | 9 | 1 | 18204 | 50 |
NTRK1 |
2.446e-02 | -3.71 | axonogenesis involved in innervation | biological process | GO:0060385 | 9 | 1 | 18204 | 50 |
NTRK1 |
2.446e-02 | -3.71 | respiratory burst involved in defense response | biological process | GO:0002679 | 9 | 1 | 18204 | 50 |
HCK |
2.446e-02 | -3.71 | iris morphogenesis | biological process | GO:0061072 | 9 | 1 | 18204 | 50 |
HIPK2 |
2.446e-02 | -3.71 | gamma-delta T cell differentiation | biological process | GO:0042492 | 9 | 1 | 18204 | 50 |
SYK |
2.446e-02 | -3.71 | negative regulation of inflammatory response to wounding | biological process | GO:0106015 | 9 | 1 | 18204 | 50 |
PTPN6 |
2.446e-02 | -3.71 | macrophage proliferation | biological process | GO:0061517 | 9 | 1 | 18204 | 50 |
CSF1R |
2.446e-02 | -3.71 | regulation of gamma-delta T cell differentiation | biological process | GO:0045586 | 9 | 1 | 18204 | 50 |
SYK |
2.446e-02 | -3.71 | positive regulation of antigen processing and presentation | biological process | GO:0002579 | 9 | 1 | 18204 | 50 |
CD74 |
2.446e-02 | -3.71 | negative regulation of chemokine-mediated signaling pathway | biological process | GO:0070100 | 9 | 1 | 18204 | 50 |
SH2B3 |
2.446e-02 | -3.71 | peroxisome proliferator activated receptor signaling pathway | biological process | GO:0035357 | 9 | 1 | 18204 | 50 |
RXRA |
2.446e-02 | -3.71 | microglial cell proliferation | biological process | GO:0061518 | 9 | 1 | 18204 | 50 |
CSF1R |
2.446e-02 | -3.71 | Regulation of actin dynamics for phagocytic cup formation | REACTOME pathways | R-HSA-2029482 | 61 | 2 | 10285 | 41 |
SYK,ELMO1 |
2.452e-02 | -3.71 | MAGOH (mago homolog, exon junction complex subunit) | protein interactions | 4116 | 243 | 3 | 19454 | 50 |
RPL27A,RPL13A,RPL8 |
2.468e-02 | -3.70 | lung-carcinoma-bronchioloalveolar_adenocarcinoma | COSMIC cancer mutations | lung-carcinoma-bronchioloalveolar_adenocarcinoma | 778 | 6 | 16828 | 49 |
CSF1R,HCK,SYK,BMP2K,NTRK1,HIPK2 |
2.468e-02 | -3.70 | bronchioloalveolar_adenocarcinoma | COSMIC cancer mutations | bronchioloalveolar_adenocarcinoma | 778 | 6 | 16828 | 49 |
CSF1R,NTRK1,HCK,SYK,BMP2K,HIPK2 |
2.479e-02 | -3.70 | EIF2S1 (eukaryotic translation initiation factor 2 subunit alpha) | protein interactions | 1965 | 244 | 3 | 19454 | 50 |
RPL27A,NTRK1,CD74 |
2.483e-02 | -3.70 | PNPLA6 (patatin like phospholipase domain containing 6) | protein interactions | 10908 | 95 | 2 | 19454 | 50 |
NTRK1,SLC13A1 |
2.488e-02 | -3.69 | skin-foot-malignant_melanoma | COSMIC cancer mutations | skin-foot-malignant_melanoma | 84 | 2 | 16828 | 49 |
DCC,ADAM28 |
2.501e-02 | -3.69 | MHD1 | prosite domains | PS51258 | 7 | 1 | 12186 | 44 |
CADPS2 |
2.501e-02 | -3.69 | SAP_B | prosite domains | PS50015 | 7 | 1 | 12186 | 44 |
PSAP |
2.501e-02 | -3.69 | PH_12 | pfam domains | PF16457 | 9 | 1 | 17795 | 50 |
ELMO1 |
2.501e-02 | -3.69 | Drf_FH3 | pfam domains | PF06367 | 9 | 1 | 17795 | 50 |
DIAPH2 |
2.501e-02 | -3.69 | Drf_GBD | pfam domains | PF06371 | 9 | 1 | 17795 | 50 |
DIAPH2 |
2.501e-02 | -3.69 | BRICHOS | pfam domains | PF04089 | 9 | 1 | 17795 | 50 |
ITM2B |
2.529e-02 | -3.68 | Platelet activation, signaling and aggregation | REACTOME pathways | R-HSA-76002 | 282 | 4 | 10285 | 41 |
SYK,PSAP,GNAI2,PTPN6 |
2.530e-02 | -3.68 | MRPS26 (mitochondrial ribosomal protein S26) | protein interactions | 64949 | 435 | 4 | 19454 | 50 |
SYK,RPL35,RPL13A,RBM47 |
2.531e-02 | -3.68 | MAP2K3 (mitogen-activated protein kinase kinase 3) | protein interactions | 5606 | 246 | 3 | 19454 | 50 |
RPS26,RPL36A,RPS3A |
2.532e-02 | -3.68 | SPTY2D1 (SPT2 chromatin protein domain containing 1) | protein interactions | 144108 | 96 | 2 | 19454 | 50 |
RPL13A,RPS14 |
2.532e-02 | -3.68 | PINX1 (PIN2 (TERF1) interacting telomerase inhibitor 1) | protein interactions | 54984 | 96 | 2 | 19454 | 50 |
RPL8,RPS3A |
2.532e-02 | -3.68 | SOD2 (superoxide dismutase 2) | protein interactions | 6648 | 96 | 2 | 19454 | 50 |
CTSS,RPS3A |
2.532e-02 | -3.68 | PRIM2 (DNA primase subunit 2) | protein interactions | 5558 | 96 | 2 | 19454 | 50 |
RPL35,NTRK1 |
2.541e-02 | -3.67 | IFNL3 (interferon lambda 3) | protein interactions | 282617 | 10 | 1 | 19454 | 50 |
DCC |
2.541e-02 | -3.67 | FCER2 (Fc epsilon receptor II) | protein interactions | 2208 | 10 | 1 | 19454 | 50 |
ITGAX |
2.541e-02 | -3.67 | Mau2 (MAU2 sister chromatid cohesion factor) | protein interactions | 74549 | 10 | 1 | 19454 | 50 |
SPECC1 |
2.541e-02 | -3.67 | Kif20a (kinesin family member 20A) | protein interactions | 19348 | 10 | 1 | 19454 | 50 |
CARD10 |
2.541e-02 | -3.67 | ZNF80 (zinc finger protein 80) | protein interactions | 7634 | 10 | 1 | 19454 | 50 |
CARD10 |
2.541e-02 | -3.67 | PGA4 (pepsinogen A4) | protein interactions | 643847 | 10 | 1 | 19454 | 50 |
CD74 |
2.541e-02 | -3.67 | SIGLEC7 (sialic acid binding Ig like lectin 7) | protein interactions | 27036 | 10 | 1 | 19454 | 50 |
PTPN6 |
2.541e-02 | -3.67 | ANKRD20A1 (ankyrin repeat domain 20 family member A1) | protein interactions | 84210 | 10 | 1 | 19454 | 50 |
PDZRN3 |
2.541e-02 | -3.67 | SIGLEC10 (sialic acid binding Ig like lectin 10) | protein interactions | 89790 | 10 | 1 | 19454 | 50 |
PTPN6 |
2.541e-02 | -3.67 | MACC1 (MET transcriptional regulator MACC1) | protein interactions | 346389 | 10 | 1 | 19454 | 50 |
FCHO2 |
2.541e-02 | -3.67 | OTP (orthopedia homeobox) | protein interactions | 23440 | 10 | 1 | 19454 | 50 |
PDE6D |
2.547e-02 | -3.67 | YWHAZ (tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein zeta) | protein interactions | 7534 | 1138 | 7 | 19454 | 50 |
GAB1,SPECC1,RAPGEF6,NTRK1,SH2B3,IVNS1ABP,CD74 |
2.558e-02 | -3.67 | AIMP1 (aminoacyl tRNA synthetase complex interacting multifunctional protein 1) | protein interactions | 9255 | 247 | 3 | 19454 | 50 |
PTPN6,RPL27A,NTRK1 |
2.570e-02 | -3.66 | Exopolyphosphatase. Domain 2 | gene3d domains | 3.30.420.150 | 8 | 1 | 14470 | 47 |
ENTPD1 |
2.581e-02 | -3.66 | SOCS3 (suppressor of cytokine signaling 3) | protein interactions | 9021 | 97 | 2 | 19454 | 50 |
CSF1R,GAB1 |
2.581e-02 | -3.66 | ATL2 (atlastin GTPase 2) | protein interactions | 64225 | 97 | 2 | 19454 | 50 |
NTRK1,RGL1 |
2.581e-02 | -3.66 | ABL2 (ABL proto-oncogene 2, non-receptor tyrosine kinase) | protein interactions | 27 | 97 | 2 | 19454 | 50 |
NTRK1,HCK |
2.581e-02 | -3.66 | KIF1A (kinesin family member 1A) | protein interactions | 547 | 97 | 2 | 19454 | 50 |
NTRK1,RXRA |
2.585e-02 | -3.66 | MECP2 (methyl-CpG binding protein 2) | protein interactions | 4204 | 248 | 3 | 19454 | 50 |
RPL12,HIPK2,RPL8 |
2.585e-02 | -3.66 | SYK (spleen associated tyrosine kinase) | protein interactions | 6850 | 248 | 3 | 19454 | 50 |
GAB1,SYK,PTPN6 |
2.586e-02 | -3.65 | ZFPL1 (zinc finger protein like 1) | protein interactions | 7542 | 438 | 4 | 19454 | 50 |
ITM2B,FCHO2,GAB1,SPECC1 |
2.587e-02 | -3.65 | immunoglobulin complex | cellular component | GO:0019814 | 10 | 1 | 19108 | 50 |
SYK |
2.589e-02 | -3.65 | shoulder | COSMIC cancer mutations | shoulder | 387 | 4 | 16828 | 49 |
DCC,ADAM28,ARAP1,NTRK1 |
2.605e-02 | -3.65 | SSR1 (signal sequence receptor subunit 1) | protein interactions | 6745 | 439 | 4 | 19454 | 50 |
RPS3A,NTRK1,PSAP,RPL35 |
2.612e-02 | -3.65 | TPR (translocated promoter region, nuclear basket protein) | protein interactions | 7175 | 249 | 3 | 19454 | 50 |
RPL18A,RPL37A,NTRK1 |
2.612e-02 | -3.65 | VPS35 (VPS35 retromer complex component) | protein interactions | 55737 | 249 | 3 | 19454 | 50 |
IVNS1ABP,NTRK1,PSAP |
2.631e-02 | -3.64 | GNAO1 (G protein subunit alpha o1) | protein interactions | 2775 | 98 | 2 | 19454 | 50 |
NTRK1,GNAI2 |
2.631e-02 | -3.64 | GOT2 (glutamic-oxaloacetic transaminase 2) | protein interactions | 2806 | 98 | 2 | 19454 | 50 |
NTRK1,CTSS |
2.631e-02 | -3.64 | PTK2B (protein tyrosine kinase 2 beta) | protein interactions | 2185 | 98 | 2 | 19454 | 50 |
SYK,PTPN6 |
2.631e-02 | -3.64 | FRS2 (fibroblast growth factor receptor substrate 2) | protein interactions | 10818 | 98 | 2 | 19454 | 50 |
GAB1,NTRK1 |
2.639e-02 | -3.63 | TFG (trafficking from ER to golgi regulator) | protein interactions | 10342 | 250 | 3 | 19454 | 50 |
NTRK1,RPS20,PTPN6 |
2.644e-02 | -3.63 | ARRB2 (arrestin beta 2) | protein interactions | 409 | 441 | 4 | 19454 | 50 |
RPL14,RPL35,RPL12,RPS3A |
2.645e-02 | -3.63 | positive regulation of transporter activity | biological process | GO:0032411 | 92 | 2 | 18204 | 50 |
RXRA,CTSS |
2.645e-02 | -3.63 | positive regulation of leukocyte chemotaxis | biological process | GO:0002690 | 92 | 2 | 18204 | 50 |
CD74,CSF1R |
2.646e-02 | -3.63 | human chr9q22.2 | chromosome location | human chr9q22.2 | 14 | 1 | 26134 | 50 |
SYK |
2.654e-02 | -3.63 | upper_arm | COSMIC cancer mutations | upper_arm | 582 | 5 | 16828 | 49 |
DCC,CSF1R,NTRK1,PDZRN3,ADAM28 |
2.668e-02 | -3.62 | Pept_asp_AS | interpro domains | IPR025661 | 10 | 1 | 18521 | 50 |
CTSS |
2.676e-02 | -3.62 | GDP phosphatase activity | molecular function | GO:0004382 | 10 | 1 | 18094 | 49 |
ENTPD1 |
2.676e-02 | -3.62 | virion binding | molecular function | GO:0046790 | 10 | 1 | 18094 | 49 |
HIPK2 |
2.676e-02 | -3.62 | AP-2 adaptor complex binding | molecular function | GO:0035612 | 10 | 1 | 18094 | 49 |
BMP2K |
2.676e-02 | -3.62 | neurotrophin binding | molecular function | GO:0043121 | 10 | 1 | 18094 | 49 |
NTRK1 |
2.676e-02 | -3.62 | glycosphingolipid binding | molecular function | GO:0043208 | 10 | 1 | 18094 | 49 |
PSAP |
2.678e-02 | -3.62 | YWHAE (tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein epsilon) | protein interactions | 7531 | 1150 | 7 | 19454 | 50 |
SH2B3,CD74,NTRK1,GAB1,RAPGEF6,SPECC1,IVNS1ABP |
2.680e-02 | -3.62 | INTS4 (integrator complex subunit 4) | protein interactions | 92105 | 99 | 2 | 19454 | 50 |
BMP2K,NTRK1 |
2.680e-02 | -3.62 | LUZP4 (leucine zipper protein 4) | protein interactions | 51213 | 99 | 2 | 19454 | 50 |
RPL35,RPL27A |
2.693e-02 | -3.61 | positive regulation of cell motility | biological process | GO:2000147 | 619 | 5 | 18204 | 50 |
GNAI2,GAB1,ITGAX,CSF1R,CD74 |
2.693e-02 | -3.61 | KIF11 (kinesin family member 11) | protein interactions | 3832 | 252 | 3 | 19454 | 50 |
RPL37A,RPS3A,NTRK1 |
2.693e-02 | -3.61 | CSDE1 (cold shock domain containing E1) | protein interactions | 7812 | 252 | 3 | 19454 | 50 |
RPS20,RBM47,NTRK1 |
2.693e-02 | -3.61 | NCK2 (NCK adaptor protein 2) | protein interactions | 8440 | 252 | 3 | 19454 | 50 |
FYB1,GAB1,ARAP1 |
2.714e-02 | -3.61 | positive regulation of monocyte differentiation | biological process | GO:0045657 | 10 | 1 | 18204 | 50 |
CD74 |
2.714e-02 | -3.61 | endothelial cell chemotaxis | biological process | GO:0035767 | 10 | 1 | 18204 | 50 |
GAB1 |
2.714e-02 | -3.61 | negative regulation of mast cell activation | biological process | GO:0033004 | 10 | 1 | 18204 | 50 |
PTPN6 |
2.714e-02 | -3.61 | regulation of vitamin D receptor signaling pathway | biological process | GO:0070562 | 10 | 1 | 18204 | 50 |
RXRA |
2.721e-02 | -3.60 | FGFBP1 (fibroblast growth factor binding protein 1) | protein interactions | 9982 | 253 | 3 | 19454 | 50 |
RPS14,RPL37A,RPL8 |
2.724e-02 | -3.60 | GPROTEINAI | prints domains | PR00441 | 8 | 1 | 5227 | 18 |
GNAI2 |
2.731e-02 | -3.60 | AP2S1 (adaptor related protein complex 2 subunit sigma 1) | protein interactions | 1175 | 100 | 2 | 19454 | 50 |
FCHO2,BMP2K |
2.731e-02 | -3.60 | AFG2B (AFG2 AAA ATPase homolog B) | protein interactions | 79029 | 100 | 2 | 19454 | 50 |
SYK,NTRK1 |
2.756e-02 | -3.59 | protein localization to cell periphery | biological process | GO:1990778 | 238 | 3 | 18204 | 50 |
RAPGEF6,FCHO2,FYB1 |
2.776e-02 | -3.58 | TEX101 (testis expressed 101) | protein interactions | 83639 | 255 | 3 | 19454 | 50 |
RPL14,RPL35,PSAP |
2.776e-02 | -3.58 | MRPS25 (mitochondrial ribosomal protein S25) | protein interactions | 64432 | 255 | 3 | 19454 | 50 |
RPL35,RBM47,RPL13A |
2.780e-02 | -3.58 | PPP1CB (protein phosphatase 1 catalytic subunit beta) | protein interactions | 5500 | 448 | 4 | 19454 | 50 |
SPECC1,BMP2K,PSAP,NTRK1 |
2.781e-02 | -3.58 | DPP9 (dipeptidyl peptidase 9) | protein interactions | 91039 | 101 | 2 | 19454 | 50 |
NTRK1,SYK |
2.781e-02 | -3.58 | ZC3H15 (zinc finger CCCH-type containing 15) | protein interactions | 55854 | 101 | 2 | 19454 | 50 |
NTRK1,RPS20 |
2.781e-02 | -3.58 | HEATR6 (HEAT repeat containing 6) | protein interactions | 63897 | 101 | 2 | 19454 | 50 |
RPS20,NTRK1 |
2.792e-02 | -3.58 | LAX1 (lymphocyte transmembrane adaptor 1) | protein interactions | 54900 | 11 | 1 | 19454 | 50 |
SYK |
2.792e-02 | -3.58 | MYBL1 (MYB proto-oncogene like 1) | protein interactions | 4603 | 11 | 1 | 19454 | 50 |
HIPK2 |
2.792e-02 | -3.58 | TM4SF1 (transmembrane 4 L six family member 1) | protein interactions | 4071 | 11 | 1 | 19454 | 50 |
SLC13A1 |
2.792e-02 | -3.58 | LAT2 (linker for activation of T cells family member 2) | protein interactions | 7462 | 11 | 1 | 19454 | 50 |
GAB1 |
2.792e-02 | -3.58 | Supt5 (suppressor of Ty 5, DSIF elongation factor subunit) | protein interactions | 20924 | 11 | 1 | 19454 | 50 |
RPL8 |
2.792e-02 | -3.58 | RGS5 (regulator of G protein signaling 5) | protein interactions | 8490 | 11 | 1 | 19454 | 50 |
GNAI2 |
2.831e-02 | -3.56 | ankle | COSMIC cancer mutations | ankle | 398 | 4 | 16828 | 49 |
DCC,ADAM28,RGL1,SLC13A1 |
2.832e-02 | -3.56 | ATXN2L (ataxin 2 like) | protein interactions | 11273 | 257 | 3 | 19454 | 50 |
RPL8,RPS20,NTRK1 |
2.832e-02 | -3.56 | SPAG9 (sperm associated antigen 9) | protein interactions | 9043 | 257 | 3 | 19454 | 50 |
NTRK1,IVNS1ABP,RPS14 |
2.832e-02 | -3.56 | TSN (translin) | protein interactions | 7247 | 102 | 2 | 19454 | 50 |
PSAP,RPS20 |
2.832e-02 | -3.56 | RANBP3 (RAN binding protein 3) | protein interactions | 8498 | 102 | 2 | 19454 | 50 |
NTRK1,RPL27A |
2.832e-02 | -3.56 | FASLG (Fas ligand) | protein interactions | 356 | 102 | 2 | 19454 | 50 |
FYB1,HCK |
2.842e-02 | -3.56 | CIC (capicua transcriptional repressor) | protein interactions | 23152 | 671 | 5 | 19454 | 50 |
IVNS1ABP,RPS14,NTRK1,RPS3A,RPS20 |
2.846e-02 | -3.56 | exocytosis | biological process | GO:0006887 | 241 | 3 | 18204 | 50 |
CADPS2,SYK,HCK |
2.853e-02 | -3.56 | RECEPTOR_TYR_KIN_III | prosite domains | PS00240 | 8 | 1 | 12186 | 44 |
CSF1R |
2.853e-02 | -3.56 | GDA1_CD39_NTPASE | prosite domains | PS01238 | 8 | 1 | 12186 | 44 |
ENTPD1 |
2.853e-02 | -3.56 | DAD | prosite domains | PS51231 | 8 | 1 | 12186 | 44 |
DIAPH2 |
2.860e-02 | -3.55 | UBAP2L (ubiquitin associated protein 2 like) | protein interactions | 9898 | 258 | 3 | 19454 | 50 |
NTRK1,RPS20,RBM47 |
2.862e-02 | -3.55 | negative regulation of response to wounding | biological process | GO:1903035 | 96 | 2 | 18204 | 50 |
PTPN6,SH2B3 |
2.862e-02 | -3.55 | pleura | COSMIC cancer mutations | pleura | 4914 | 21 | 16828 | 49 |
RPL36A,PDZRN3,PTPN6,CSF1R,CARD10,RGL1,SH2B3,SYK,GNAI2,BMP2K,NTRK1,RAPGEF6,CTSS,GAB1,HIPK2,HCK,SPECC1,CADPS2,ADAM28,DIAPH2,ITGAX |
2.879e-02 | -3.55 | JUP (junction plakoglobin) | protein interactions | 3728 | 453 | 4 | 19454 | 50 |
NTRK1,RPS3A,RPL12,GAB1 |
2.884e-02 | -3.55 | LSM14B (LSM family member 14B) | protein interactions | 149986 | 103 | 2 | 19454 | 50 |
RPS20,NTRK1 |
2.884e-02 | -3.55 | CENPQ (centromere protein Q) | protein interactions | 55166 | 103 | 2 | 19454 | 50 |
RPS14,CARD10 |
2.884e-02 | -3.55 | NEPRO (nucleolus and neural progenitor protein) | protein interactions | 25871 | 103 | 2 | 19454 | 50 |
RPL18A,RPL27A |
2.886e-02 | -3.55 | - | gene3d domains | 1.10.357.50 | 9 | 1 | 14470 | 47 |
CADPS2 |
2.886e-02 | -3.55 | Saposin-like | gene3d domains | 1.10.225.10 | 9 | 1 | 14470 | 47 |
PSAP |
2.900e-02 | -3.54 | PSMC5 (proteasome 26S subunit, ATPase 5) | protein interactions | 5705 | 454 | 4 | 19454 | 50 |
PTPN6,NTRK1,RXRA,RPS14 |
2.902e-02 | -3.54 | leukocyte differentiation | biological process | GO:0002521 | 425 | 4 | 18204 | 50 |
CD74,CSF1R,NTRK1,SYK |
2.912e-02 | -3.54 | Signaling by PTK6 | REACTOME pathways | R-HSA-8848021 | 67 | 2 | 10285 | 41 |
ELMO1,ARAP1 |
2.928e-02 | -3.53 | positive regulation of locomotion | biological process | GO:0040017 | 633 | 5 | 18204 | 50 |
CD74,CSF1R,ITGAX,GNAI2,GAB1 |
2.931e-02 | -3.53 | Znf_TRAF | interpro domains | IPR001293 | 11 | 1 | 18521 | 50 |
PDZRN3 |
2.931e-02 | -3.53 | GBD/FH3_dom | interpro domains | IPR014768 | 11 | 1 | 18521 | 50 |
DIAPH2 |
2.931e-02 | -3.53 | Pept_his_AS | interpro domains | IPR025660 | 11 | 1 | 18521 | 50 |
CTSS |
2.931e-02 | -3.53 | Tyr_kinase_rcpt_2_CS | interpro domains | IPR002011 | 11 | 1 | 18521 | 50 |
NTRK1 |
2.936e-02 | -3.53 | TBCB (tubulin folding cofactor B) | protein interactions | 1155 | 104 | 2 | 19454 | 50 |
NTRK1,RPL35 |
2.936e-02 | -3.53 | RRP7A (ribosomal RNA processing 7 homolog A) | protein interactions | 27341 | 104 | 2 | 19454 | 50 |
RPS20,RPL18A |
2.936e-02 | -3.53 | MDM4 (MDM4 regulator of p53) | protein interactions | 4194 | 104 | 2 | 19454 | 50 |
HIPK2,RPS20 |
2.936e-02 | -3.53 | DDX51 (DEAD-box helicase 51) | protein interactions | 317781 | 104 | 2 | 19454 | 50 |
RPL13A,RPL18A |
2.936e-02 | -3.53 | COG4 (component of oligomeric golgi complex 4) | protein interactions | 25839 | 104 | 2 | 19454 | 50 |
RPS20,NTRK1 |
2.937e-02 | -3.53 | negative regulation of apoptotic signaling pathway | biological process | GO:2001234 | 244 | 3 | 18204 | 50 |
IVNS1ABP,CD74,GNAI2 |
2.940e-02 | -3.53 | secondary active sulfate transmembrane transporter activity | molecular function | GO:0008271 | 11 | 1 | 18094 | 49 |
SLC13A1 |
2.940e-02 | -3.53 | MDM2/MDM4 family protein binding | molecular function | GO:0097371 | 11 | 1 | 18094 | 49 |
RPS20 |
2.940e-02 | -3.53 | ubiquitin-protein transferase inhibitor activity | molecular function | GO:0055105 | 11 | 1 | 18094 | 49 |
RPS20 |
2.940e-02 | -3.53 | nitric-oxide synthase binding | molecular function | GO:0050998 | 11 | 1 | 18094 | 49 |
CD74 |
2.946e-02 | -3.52 | DIRAS3 (DIRAS family GTPase 3) | protein interactions | 9077 | 261 | 3 | 19454 | 50 |
GAB1,SPECC1,FCHO2 |
2.951e-02 | -3.52 | immune response | biological process | GO:0006955 | 1349 | 8 | 18204 | 50 |
PTPN6,CTSS,RPL13A,SYK,CD74,HCK,FYB1,CSF1R |
2.968e-02 | -3.52 | negative regulation of response to external stimulus | biological process | GO:0032102 | 428 | 4 | 18204 | 50 |
SYK,PTPN6,SH2B3,HCK |
2.968e-02 | -3.52 | leukocyte migration | biological process | GO:0050900 | 245 | 3 | 18204 | 50 |
HCK,SYK,RPL13A |
2.972e-02 | -3.52 | kidney-carcinoma | COSMIC cancer mutations | kidney-carcinoma | 3720 | 17 | 16828 | 49 |
CSF1R,RGL1,CARD10,SYK,BMP2K,GNAI2,PDZRN3,PTPN6,HCK,SPECC1,ADAM28,ITGAX,NTRK1,RAPGEF6,RXRA,HIPK2,GAB1 |
2.981e-02 | -3.51 | collagen-activated tyrosine kinase receptor signaling pathway | biological process | GO:0038063 | 11 | 1 | 18204 | 50 |
SYK |
2.981e-02 | -3.51 | regulation of dendritic cell antigen processing and presentation | biological process | GO:0002604 | 11 | 1 | 18204 | 50 |
CD74 |
2.981e-02 | -3.51 | prostate gland growth | biological process | GO:0060736 | 11 | 1 | 18204 | 50 |
PSAP |
2.981e-02 | -3.51 | negative regulation of platelet aggregation | biological process | GO:0090331 | 11 | 1 | 18204 | 50 |
SH2B3 |
2.981e-02 | -3.51 | regulation of gamma-delta T cell activation | biological process | GO:0046643 | 11 | 1 | 18204 | 50 |
SYK |
2.981e-02 | -3.51 | negative regulation of collateral sprouting | biological process | GO:0048671 | 11 | 1 | 18204 | 50 |
DCC |
2.981e-02 | -3.51 | positive regulation of chemokine (C-X-C motif) ligand 2 production | biological process | GO:2000343 | 11 | 1 | 18204 | 50 |
CD74 |
2.981e-02 | -3.51 | negative regulation of humoral immune response mediated by circulating immunoglobulin | biological process | GO:0002924 | 11 | 1 | 18204 | 50 |
PTPN6 |
2.981e-02 | -3.51 | epithelial cell differentiation involved in prostate gland development | biological process | GO:0060742 | 11 | 1 | 18204 | 50 |
PSAP |
2.981e-02 | -3.51 | response to glycoprotein | biological process | GO:1904587 | 11 | 1 | 18204 | 50 |
MAN1C1 |
2.988e-02 | -3.51 | CENPU (centromere protein U) | protein interactions | 79682 | 105 | 2 | 19454 | 50 |
IVNS1ABP,RPL18A |
2.988e-02 | -3.51 | SLC27A4 (solute carrier family 27 member 4) | protein interactions | 10999 | 105 | 2 | 19454 | 50 |
GNAI2,NTRK1 |
2.988e-02 | -3.51 | EIF4H (eukaryotic translation initiation factor 4H) | protein interactions | 7458 | 105 | 2 | 19454 | 50 |
NTRK1,RPS20 |
2.989e-02 | -3.51 | response to external stimulus | biological process | GO:0009605 | 1882 | 10 | 18204 | 50 |
ITGAX,HCK,CD74,RPL13A,SYK,GAB1,PTPN6,IVNS1ABP,CSF1R,NTRK1 |
2.999e-02 | -3.51 | regulation of cell morphogenesis | biological process | GO:0022604 | 246 | 3 | 18204 | 50 |
HCK,CSF1R,ARAP1 |
3.012e-02 | -3.50 | positive regulation of defense response | biological process | GO:0031349 | 430 | 4 | 18204 | 50 |
RBM47,HCK,CTSS,SYK |
3.015e-02 | -3.50 | nucleus | cellular component | GO:0005634 | 7993 | 28 | 19108 | 50 |
CSF1R,RPL13A,RPS25,CD74,RXRA,HIPK2,RBM47,FYB1,RPL27A,BMP2K,SPECC1,PTPN6,RPL34,RPS14,ARAP1,RPS26,RPL35,IVNS1ABP,CADPS2,RPS3A,DIAPH2,RPS20,SYK,RPL37A,HCK,RPL12,GNAI2,RPL8 |
3.017e-02 | -3.50 | Drf_FH3 | smart domains | SM01139 | 9 | 1 | 9717 | 33 |
DIAPH2 |
3.017e-02 | -3.50 | BRICHOS | smart domains | SM01039 | 9 | 1 | 9717 | 33 |
ITM2B |
3.017e-02 | -3.50 | Drf_GBD | smart domains | SM01140 | 9 | 1 | 9717 | 33 |
DIAPH2 |
3.017e-02 | -3.50 | Neurotrophin signaling pathway | KEGG pathways | hsa04722 | 119 | 3 | 7161 | 41 |
GAB1,NTRK1,SH2B3 |
3.017e-02 | -3.50 | Neurotrophin signaling pathway | KEGG pathways | ko04722 | 119 | 3 | 7161 | 41 |
GAB1,SH2B3,NTRK1 |
3.034e-02 | -3.50 | response to wounding | biological process | GO:0009611 | 431 | 4 | 18204 | 50 |
SYK,NTRK1,PTPN6,ENTPD1 |
3.036e-02 | -3.49 | AURKA (aurora kinase A) | protein interactions | 6790 | 683 | 5 | 19454 | 50 |
RPL12,RAPGEF6,RPL35,RPS14,RPS3A |
3.040e-02 | -3.49 | CCDC59 (coiled-coil domain containing 59) | protein interactions | 29080 | 106 | 2 | 19454 | 50 |
RPL18A,RPS14 |
3.040e-02 | -3.49 | EFNA3 (ephrin A3) | protein interactions | 1944 | 106 | 2 | 19454 | 50 |
RPS3A,RPL12 |
3.040e-02 | -3.49 | HSP90AB2P (heat shock protein 90 alpha family class B member 2, pseudogene) | protein interactions | 391634 | 106 | 2 | 19454 | 50 |
HCK,NTRK1 |
3.042e-02 | -3.49 | LTB4R (leukotriene B4 receptor) | protein interactions | 1241 | 12 | 1 | 19454 | 50 |
GNAI2 |
3.042e-02 | -3.49 | PCP2 (Purkinje cell protein 2) | protein interactions | 126006 | 12 | 1 | 19454 | 50 |
GNAI2 |
3.042e-02 | -3.49 | ROPN1L (rhophilin associated tail protein 1 like) | protein interactions | 83853 | 12 | 1 | 19454 | 50 |
CD74 |
3.042e-02 | -3.49 | ZNF492 (zinc finger protein 492) | protein interactions | 57615 | 12 | 1 | 19454 | 50 |
RPL27A |
3.042e-02 | -3.49 | LGR5 (leucine rich repeat containing G protein-coupled receptor 5) | protein interactions | 8549 | 12 | 1 | 19454 | 50 |
NTRK1 |
3.042e-02 | -3.49 | SSTR2 (somatostatin receptor 2) | protein interactions | 6752 | 12 | 1 | 19454 | 50 |
PTPN6 |
3.042e-02 | -3.49 | RWDD1 (RWD domain containing 1) | protein interactions | 51389 | 12 | 1 | 19454 | 50 |
CD74 |
3.042e-02 | -3.49 | ZNF559 (zinc finger protein 559) | protein interactions | 84527 | 12 | 1 | 19454 | 50 |
CARD10 |
3.042e-02 | -3.49 | PDC (phosducin) | protein interactions | 5132 | 12 | 1 | 19454 | 50 |
DCC |
3.042e-02 | -3.49 | SIRPB1 (signal regulatory protein beta 1) | protein interactions | 10326 | 12 | 1 | 19454 | 50 |
SYK |
3.042e-02 | -3.49 | PTPN20 (protein tyrosine phosphatase non-receptor type 20) | protein interactions | 26095 | 12 | 1 | 19454 | 50 |
PTPN6 |
3.042e-02 | -3.49 | ROBO4 (roundabout guidance receptor 4) | protein interactions | 54538 | 12 | 1 | 19454 | 50 |
RXRA |
3.042e-02 | -3.49 | ZNF10 (zinc finger protein 10) | protein interactions | 7556 | 12 | 1 | 19454 | 50 |
CARD10 |
3.042e-02 | -3.49 | PNMT (phenylethanolamine N-methyltransferase) | protein interactions | 5409 | 12 | 1 | 19454 | 50 |
HCK |
3.042e-02 | -3.49 | ADGRB3 (adhesion G protein-coupled receptor B3) | protein interactions | 577 | 12 | 1 | 19454 | 50 |
ELMO1 |
3.042e-02 | -3.49 | TBC1D26 (TBC1 domain family member 26) | protein interactions | 353149 | 12 | 1 | 19454 | 50 |
CARD10 |
3.062e-02 | -3.49 | OSBPL8 (oxysterol binding protein like 8) | protein interactions | 114882 | 265 | 3 | 19454 | 50 |
NTRK1,CD74,SYK |
3.074e-02 | -3.48 | regulation of transport | biological process | GO:0051049 | 1621 | 9 | 18204 | 50 |
CADPS2,CTSS,PTPN6,SYK,GNAI2,CD74,HCK,RXRA,BMP2K |
3.078e-02 | -3.48 | protein domain specific binding | molecular function | GO:0019904 | 651 | 5 | 18094 | 49 |
SYK,PTPN6,CARD10,RXRA,ELMO1 |
3.085e-02 | -3.48 | positive regulation of interleukin-6 production | biological process | GO:0032755 | 100 | 2 | 18204 | 50 |
SYK,CD74 |
3.092e-02 | -3.48 | cell differentiation | biological process | GO:0030154 | 3645 | 16 | 18204 | 50 |
HCK,PTPN6,DIAPH2,PSAP,HIPK2,RPS3A,RAPGEF6,RPS14,SH2B3,RBM47,DCC,CD74,RXRA,SYK,CSF1R,NTRK1 |
3.093e-02 | -3.48 | TPP2 (tripeptidyl peptidase 2) | protein interactions | 7174 | 107 | 2 | 19454 | 50 |
CD74,NTRK1 |
3.093e-02 | -3.48 | IQGAP2 (IQ motif containing GTPase activating protein 2) | protein interactions | 10788 | 107 | 2 | 19454 | 50 |
GNAI2,CD74 |
3.100e-02 | -3.47 | RHOA (ras homolog family member A) | protein interactions | 387 | 1186 | 7 | 19454 | 50 |
SLC13A1,RPL13A,DIAPH2,PDE6D,GNAI2,GAB1,SPECC1 |
3.107e-02 | -3.47 | EEF2 (eukaryotic translation elongation factor 2) | protein interactions | 1938 | 464 | 4 | 19454 | 50 |
RPL12,RPL14,NTRK1,RPS3A |
3.113e-02 | -3.47 | response to other organism | biological process | GO:0051707 | 1363 | 8 | 18204 | 50 |
CD74,ITGAX,HCK,PTPN6,SYK,RPL13A,CSF1R,IVNS1ABP |
3.114e-02 | -3.47 | cellular developmental process | biological process | GO:0048869 | 3648 | 16 | 18204 | 50 |
CSF1R,NTRK1,RXRA,CD74,SYK,SH2B3,RBM47,RAPGEF6,RPS14,HIPK2,RPS3A,DCC,HCK,PSAP,DIAPH2,PTPN6 |
3.122e-02 | -3.47 | Rap1 signaling pathway | KEGG pathways | ko04015 | 210 | 4 | 7161 | 41 |
RAPGEF6,GNAI2,CSF1R,FYB1 |
3.122e-02 | -3.47 | Rap1 signaling pathway | KEGG pathways | hsa04015 | 210 | 4 | 7161 | 41 |
RAPGEF6,GNAI2,CSF1R,FYB1 |
3.137e-02 | -3.46 | amide binding | molecular function | GO:0033218 | 254 | 3 | 18094 | 49 |
CD74,ITM2B,PSAP |
3.143e-02 | -3.46 | nucleoplasm | cellular component | GO:0005654 | 4159 | 17 | 19108 | 50 |
RPL27A,SPECC1,BMP2K,GNAI2,PTPN6,RPL8,ARAP1,RPS25,RPS14,CSF1R,RPS3A,CADPS2,RPS20,HIPK2,RPS26,RXRA,IVNS1ABP |
3.146e-02 | -3.46 | Phosphate bond hydrolysis by NTPDase proteins | REACTOME pathways | R-HSA-8850843 | 8 | 1 | 10285 | 41 |
ENTPD1 |
3.147e-02 | -3.46 | DRD2 (dopamine receptor D2) | protein interactions | 1813 | 108 | 2 | 19454 | 50 |
CADPS2,GNAI2 |
3.147e-02 | -3.46 | PPP4R2 (protein phosphatase 4 regulatory subunit 2) | protein interactions | 151987 | 108 | 2 | 19454 | 50 |
RPL18A,SYK |
3.147e-02 | -3.46 | PTK7 (protein tyrosine kinase 7 (inactive)) | protein interactions | 5754 | 108 | 2 | 19454 | 50 |
PTPN6,NTRK1 |
3.147e-02 | -3.46 | RIN1 (Ras and Rab interactor 1) | protein interactions | 9610 | 108 | 2 | 19454 | 50 |
CARD10,IVNS1ABP |
3.147e-02 | -3.46 | REPIN1 (replication initiator 1) | protein interactions | 29803 | 108 | 2 | 19454 | 50 |
RPL13A,RPL35 |
3.147e-02 | -3.46 | TRADD (TNFRSF1A associated via death domain) | protein interactions | 8717 | 108 | 2 | 19454 | 50 |
RXRA,HIPK2 |
3.147e-02 | -3.46 | ASF1B (anti-silencing function 1B histone chaperone) | protein interactions | 55723 | 108 | 2 | 19454 | 50 |
RPS20,RPS3A |
3.149e-02 | -3.46 | PFN1 (profilin 1) | protein interactions | 5216 | 466 | 4 | 19454 | 50 |
NTRK1,DIAPH2,FCHO2,RAPGEF6 |
3.149e-02 | -3.46 | response to external biotic stimulus | biological process | GO:0043207 | 1366 | 8 | 18204 | 50 |
IVNS1ABP,CSF1R,ITGAX,HCK,CD74,SYK,RPL13A,PTPN6 |
3.151e-02 | -3.46 | ADAR (adenosine deaminase RNA specific) | protein interactions | 103 | 268 | 3 | 19454 | 50 |
NTRK1,RPL18A,RPS14 |
3.151e-02 | -3.46 | EIF3H (eukaryotic translation initiation factor 3 subunit H) | protein interactions | 8667 | 268 | 3 | 19454 | 50 |
RPS20,CD74,NTRK1 |
3.196e-02 | -3.44 | preribosome | cellular component | GO:0030684 | 107 | 2 | 19108 | 50 |
RPS3A,RPS14 |
3.199e-02 | -3.44 | regulation of phagocytosis | biological process | GO:0050764 | 102 | 2 | 18204 | 50 |
HCK,SYK |
3.199e-02 | -3.44 | regulation of interleukin-8 production | biological process | GO:0032677 | 102 | 2 | 18204 | 50 |
SYK,CD74 |
3.200e-02 | -3.44 | MBP (myelin basic protein) | protein interactions | 4155 | 109 | 2 | 19454 | 50 |
HIPK2,BMP2K |
3.200e-02 | -3.44 | ARL15 (ADP ribosylation factor like GTPase 15) | protein interactions | 54622 | 109 | 2 | 19454 | 50 |
PDE6D,RPL8 |
3.200e-02 | -3.44 | ACOT2 (acyl-CoA thioesterase 2) | protein interactions | 10965 | 109 | 2 | 19454 | 50 |
SLC13A1,NTRK1 |
3.200e-02 | -3.44 | RABGAP1 (RAB GTPase activating protein 1) | protein interactions | 23637 | 109 | 2 | 19454 | 50 |
RPS14,NTRK1 |
3.203e-02 | -3.44 | neurotrophin receptor binding | molecular function | GO:0005165 | 12 | 1 | 18094 | 49 |
NTRK1 |
3.203e-02 | -3.44 | non-membrane spanning protein tyrosine phosphatase activity | molecular function | GO:0004726 | 12 | 1 | 18094 | 49 |
PTPN6 |
3.203e-02 | -3.44 | GTPase inhibitor activity | molecular function | GO:0005095 | 12 | 1 | 18094 | 49 |
PDE6D |
3.204e-02 | -3.44 | BRICHOS | prosite domains | PS50869 | 9 | 1 | 12186 | 44 |
ITM2B |
3.211e-02 | -3.44 | MRPS2 (mitochondrial ribosomal protein S2) | protein interactions | 51116 | 270 | 3 | 19454 | 50 |
HCK,NTRK1,RBM47 |
3.211e-02 | -3.44 | TCOF1 (treacle ribosome biogenesis factor 1) | protein interactions | 6949 | 270 | 3 | 19454 | 50 |
NTRK1,PSAP,SYK |
3.248e-02 | -3.43 | regulation of chemokine-mediated signaling pathway | biological process | GO:0070099 | 12 | 1 | 18204 | 50 |
SH2B3 |
3.248e-02 | -3.43 | negative thymic T cell selection | biological process | GO:0045060 | 12 | 1 | 18204 | 50 |
CD74 |
3.248e-02 | -3.43 | regulation of prostaglandin biosynthetic process | biological process | GO:0031392 | 12 | 1 | 18204 | 50 |
CD74 |
3.248e-02 | -3.43 | serotonin transport | biological process | GO:0006837 | 12 | 1 | 18204 | 50 |
SYK |
3.248e-02 | -3.43 | cellular response to thyroid hormone stimulus | biological process | GO:0097067 | 12 | 1 | 18204 | 50 |
CTSS |
3.248e-02 | -3.43 | response to macrophage colony-stimulating factor | biological process | GO:0036005 | 12 | 1 | 18204 | 50 |
CSF1R |
3.248e-02 | -3.43 | positive thymic T cell selection | biological process | GO:0045059 | 12 | 1 | 18204 | 50 |
CD74 |
3.248e-02 | -3.43 | cytidine to uridine editing | biological process | GO:0016554 | 12 | 1 | 18204 | 50 |
RBM47 |
3.248e-02 | -3.43 | regulation of inflammatory response to wounding | biological process | GO:0106014 | 12 | 1 | 18204 | 50 |
PTPN6 |
3.254e-02 | -3.43 | REEP6 (receptor accessory protein 6) | protein interactions | 92840 | 110 | 2 | 19454 | 50 |
RPS20,DCC |
3.254e-02 | -3.43 | WDR74 (WD repeat domain 74) | protein interactions | 54663 | 110 | 2 | 19454 | 50 |
RPL35,RPL13A |
3.257e-02 | -3.42 | regulation of biomineral tissue development | biological process | GO:0070167 | 103 | 2 | 18204 | 50 |
RXRA,BMP2K |
3.263e-02 | -3.42 | peptide binding | molecular function | GO:0042277 | 258 | 3 | 18094 | 49 |
CD74,RXRA,ITM2B |
3.264e-02 | -3.42 | functioning | COSMIC cancer mutations | functioning | 1803 | 10 | 16828 | 49 |
CSF1R,CADPS2,ITGAX,ENTPD1,RXRA,RAPGEF6,ELMO1,PTPN6,DCC,CTSS |
3.264e-02 | -3.42 | adrenal_gland-adrenal_gland-adrenal_cortical_carcinoma-functioning | COSMIC cancer mutations | adrenal_gland-adrenal_gland-adrenal_cortical_carcinoma-functioning | 1803 | 10 | 16828 | 49 |
ITGAX,CSF1R,CADPS2,CTSS,DCC,PTPN6,ELMO1,RAPGEF6,RXRA,ENTPD1 |
3.286e-02 | -3.42 | positive regulation of T cell activation | biological process | GO:0050870 | 255 | 3 | 18204 | 50 |
CD74,PTPN6,SYK |
3.291e-02 | -3.41 | KCNQ4 (potassium voltage-gated channel subfamily Q member 4) | protein interactions | 9132 | 13 | 1 | 19454 | 50 |
CSF1R |
3.291e-02 | -3.41 | Kif20b (kinesin family member 20B) | protein interactions | 240641 | 13 | 1 | 19454 | 50 |
DIAPH2 |
3.291e-02 | -3.41 | C1orf74 (chromosome 1 open reading frame 74) | protein interactions | 148304 | 13 | 1 | 19454 | 50 |
HCK |
3.291e-02 | -3.41 | NGF (nerve growth factor) | protein interactions | 4803 | 13 | 1 | 19454 | 50 |
NTRK1 |
3.291e-02 | -3.41 | Nfya (nuclear transcription factor-Y alpha) | protein interactions | 18044 | 13 | 1 | 19454 | 50 |
IVNS1ABP |
3.291e-02 | -3.41 | PPP1R2B (PPP1R2 family member B) | protein interactions | 153743 | 13 | 1 | 19454 | 50 |
BMP2K |
3.291e-02 | -3.41 | DPH3 (diphthamide biosynthesis 3) | protein interactions | 285381 | 13 | 1 | 19454 | 50 |
RPL8 |
3.291e-02 | -3.41 | NFAM1 (NFAT activating protein with ITAM motif 1) | protein interactions | 150372 | 13 | 1 | 19454 | 50 |
SYK |
3.291e-02 | -3.41 | Tpm4 (tropomyosin 4) | protein interactions | 326618 | 13 | 1 | 19454 | 50 |
SPECC1 |
3.291e-02 | -3.41 | SEMA4A (semaphorin 4A) | protein interactions | 64218 | 13 | 1 | 19454 | 50 |
RPS20 |
3.294e-02 | -3.41 | Signaling events mediated by PTP1B | Pathway Interaction DB | ptp1bpathway | 50 | 2 | 2226 | 13 |
HCK,CSF1R |
3.306e-02 | -3.41 | bone-tibia-other-chondroblastoma | COSMIC cancer mutations | bone-tibia-other-chondroblastoma | 98 | 2 | 16828 | 49 |
PDZRN3,DIAPH2 |
3.309e-02 | -3.41 | PCK1 (phosphoenolpyruvate carboxykinase 1) | protein interactions | 5105 | 111 | 2 | 19454 | 50 |
RPL14,RPS3A |
3.309e-02 | -3.41 | GIPC1 (GIPC PDZ domain containing family member 1) | protein interactions | 10755 | 111 | 2 | 19454 | 50 |
CARD10,NTRK1 |
3.333e-02 | -3.40 | USP10 (ubiquitin specific peptidase 10) | protein interactions | 9100 | 274 | 3 | 19454 | 50 |
NTRK1,RPS3A,RPS20 |
3.333e-02 | -3.40 | ATG3 (autophagy related 3) | protein interactions | 64422 | 274 | 3 | 19454 | 50 |
RPS14,RPL8,RPS3A |
3.350e-02 | -3.40 | early phagosome | cellular component | GO:0032009 | 13 | 1 | 19108 | 50 |
SYK |
3.363e-02 | -3.39 | CENPV (centromere protein V) | protein interactions | 201161 | 112 | 2 | 19454 | 50 |
RPL37A,RPS14 |
3.363e-02 | -3.39 | TSPYL1 (TSPY like 1) | protein interactions | 7259 | 112 | 2 | 19454 | 50 |
RPL8,RPL18A |
3.363e-02 | -3.39 | ENAH (ENAH actin regulator) | protein interactions | 55740 | 112 | 2 | 19454 | 50 |
FYB1,NTRK1 |
3.363e-02 | -3.39 | C10orf88 (chromosome 10 open reading frame 88) | protein interactions | 80007 | 112 | 2 | 19454 | 50 |
RBM47,BMP2K |
3.363e-02 | -3.39 | FMR1 (fragile X messenger ribonucleoprotein 1) | protein interactions | 2332 | 275 | 3 | 19454 | 50 |
SYK,RPS20,NTRK1 |
3.373e-02 | -3.39 | antigen processing and presentation | biological process | GO:0019882 | 105 | 2 | 18204 | 50 |
CTSS,CD74 |
3.384e-02 | -3.39 | small GTPase-mediated signal transduction | biological process | GO:0007264 | 258 | 3 | 18204 | 50 |
RGL1,ELMO1,RAPGEF6 |
3.388e-02 | -3.39 | N-glycan precursor trimming | KEGG pathways | hsa_M00073 | 6 | 1 | 7161 | 41 |
MAN1C1 |
3.388e-02 | -3.39 | N-glycan precursor trimming | KEGG pathways | M00073 | 6 | 1 | 7161 | 41 |
MAN1C1 |
3.389e-02 | -3.38 | human chr4q21.21 | chromosome location | human chr4q21.21 | 18 | 1 | 26134 | 50 |
BMP2K |
3.389e-02 | -3.38 | human chr3p13 | chromosome location | human chr3p13 | 18 | 1 | 26134 | 50 |
PDZRN3 |
3.394e-02 | -3.38 | KELCHREPEAT | prints domains | PR00501 | 10 | 1 | 5227 | 18 |
IVNS1ABP |
3.394e-02 | -3.38 | PCDH7 (protocadherin 7) | protein interactions | 5099 | 276 | 3 | 19454 | 50 |
RPL18A,RPL8,PSAP |
3.418e-02 | -3.38 | transferase activity, transferring phosphorus-containing groups | molecular function | GO:0016772 | 903 | 6 | 18094 | 49 |
HCK,NTRK1,BMP2K,CSF1R,SYK,HIPK2 |
3.418e-02 | -3.38 | ERP29 (endoplasmic reticulum protein 29) | protein interactions | 10961 | 113 | 2 | 19454 | 50 |
NTRK1,CTSS |
3.418e-02 | -3.38 | Cdk1 (cyclin dependent kinase 1) | protein interactions | 12534 | 113 | 2 | 19454 | 50 |
SPECC1,GNAI2 |
3.418e-02 | -3.38 | LAT (linker for activation of T cells) | protein interactions | 27040 | 113 | 2 | 19454 | 50 |
PTPN6,SYK |
3.418e-02 | -3.38 | DOK2 (docking protein 2) | protein interactions | 9046 | 113 | 2 | 19454 | 50 |
HCK,IVNS1ABP |
3.418e-02 | -3.38 | TUT7 (terminal uridylyl transferase 7) | protein interactions | 79670 | 113 | 2 | 19454 | 50 |
RPL13A,RPL18A |
3.440e-02 | -3.37 | haematopoietic_and_lymphoid_tissue-lymph_node-lymphoid_neoplasm-angioimmunoblastic_T_cell_lymphoma | COSMIC cancer mutations | haematopoietic_and_lymphoid_tissue-lymph_node-lymphoid_neoplasm-angioimmunoblastic_T_cell_lymphoma | 12 | 1 | 16828 | 49 |
CSF1R |
3.454e-02 | -3.37 | Peptidase_C1A_C | interpro domains | IPR000668 | 13 | 1 | 18521 | 50 |
CTSS |
3.454e-02 | -3.37 | Peptidase_C1A | interpro domains | IPR013128 | 13 | 1 | 18521 | 50 |
CTSS |
3.457e-02 | -3.36 | CBX6 (chromobox 6) | protein interactions | 23466 | 278 | 3 | 19454 | 50 |
RPL37A,RPL8,RPS3A |
3.478e-02 | -3.36 | MAP1B (microtubule associated protein 1B) | protein interactions | 4131 | 481 | 4 | 19454 | 50 |
RPL14,RPL13A,CD74,NTRK1 |
3.484e-02 | -3.36 | positive regulation of immune effector process | biological process | GO:0002699 | 261 | 3 | 18204 | 50 |
PTPN6,SYK,CD74 |
3.488e-02 | -3.36 | PUM1 (pumilio RNA binding family member 1) | protein interactions | 9698 | 279 | 3 | 19454 | 50 |
RPS20,RBM47,NTRK1 |
3.492e-02 | -3.35 | T cell receptor signaling pathway | biological process | GO:0050852 | 107 | 2 | 18204 | 50 |
PTPN6,FYB1 |
3.492e-02 | -3.35 | neuron apoptotic process | biological process | GO:0051402 | 107 | 2 | 18204 | 50 |
NTRK1,HIPK2 |
3.501e-02 | -3.35 | GNB2 (G protein subunit beta 2) | protein interactions | 2783 | 482 | 4 | 19454 | 50 |
CARD10,RPS14,GNAI2,RPL27A |
3.514e-02 | -3.35 | negative T cell selection | biological process | GO:0043383 | 13 | 1 | 18204 | 50 |
CD74 |
3.514e-02 | -3.35 | modulation of process of another organism | biological process | GO:0035821 | 13 | 1 | 18204 | 50 |
SYK |
3.514e-02 | -3.35 | positive regulation of urine volume | biological process | GO:0035810 | 13 | 1 | 18204 | 50 |
GNAI2 |
3.514e-02 | -3.35 | type II interferon-mediated signaling pathway | biological process | GO:0060333 | 13 | 1 | 18204 | 50 |
HCK |
3.514e-02 | -3.35 | response to water | biological process | GO:0009415 | 13 | 1 | 18204 | 50 |
NTRK1 |
3.514e-02 | -3.35 | negative regulation of homotypic cell-cell adhesion | biological process | GO:0034111 | 13 | 1 | 18204 | 50 |
SH2B3 |
3.530e-02 | -3.34 | HBS1L (HBS1 like translational GTPase) | protein interactions | 10767 | 115 | 2 | 19454 | 50 |
NTRK1,RPS20 |
3.530e-02 | -3.34 | CTPS2 (CTP synthase 2) | protein interactions | 56474 | 115 | 2 | 19454 | 50 |
RPL37A,NTRK1 |
3.530e-02 | -3.34 | FGF13 (fibroblast growth factor 13) | protein interactions | 2258 | 115 | 2 | 19454 | 50 |
RPS3A,RPS14 |
3.530e-02 | -3.34 | ASCC2 (activating signal cointegrator 1 complex subunit 2) | protein interactions | 84164 | 115 | 2 | 19454 | 50 |
NTRK1,RPS20 |
3.532e-02 | -3.34 | PTK6 Regulates RTKs and Their Effectors AKT1 and DOK1 | REACTOME pathways | R-HSA-8849469 | 9 | 1 | 10285 | 41 |
ARAP1 |
3.540e-02 | -3.34 | UBI4 (ubiquitin) | protein interactions | 850620 | 14 | 1 | 19454 | 50 |
DCC |
3.540e-02 | -3.34 | GRK1 (G protein-coupled receptor kinase 1) | protein interactions | 6011 | 14 | 1 | 19454 | 50 |
PDE6D |
3.540e-02 | -3.34 | Stag2 (STAG2 cohesin complex component) | protein interactions | 20843 | 14 | 1 | 19454 | 50 |
SPECC1 |
3.540e-02 | -3.34 | CNR1 (cannabinoid receptor 1) | protein interactions | 1268 | 14 | 1 | 19454 | 50 |
GNAI2 |
3.540e-02 | -3.34 | FBXL20 (F-box and leucine rich repeat protein 20) | protein interactions | 84961 | 14 | 1 | 19454 | 50 |
PDE6D |
3.540e-02 | -3.34 | AGTR2 (angiotensin II receptor type 2) | protein interactions | 186 | 14 | 1 | 19454 | 50 |
GNAI2 |
3.540e-02 | -3.34 | Ptbp1 (polypyrimidine tract binding protein 1) | protein interactions | 19205 | 14 | 1 | 19454 | 50 |
IVNS1ABP |
3.540e-02 | -3.34 | CHGA (chromogranin A) | protein interactions | 1113 | 14 | 1 | 19454 | 50 |
NTRK1 |
3.540e-02 | -3.34 | PLXNA4 (plexin A4) | protein interactions | 91584 | 14 | 1 | 19454 | 50 |
NTRK1 |
3.540e-02 | -3.34 | RGS13 (regulator of G protein signaling 13) | protein interactions | 6003 | 14 | 1 | 19454 | 50 |
GNAI2 |
3.546e-02 | -3.34 | MTDH (metadherin) | protein interactions | 92140 | 484 | 4 | 19454 | 50 |
NTRK1,RPL18A,SYK,RPL14 |
3.551e-02 | -3.34 | DHX36 (DEAH-box helicase 36) | protein interactions | 170506 | 281 | 3 | 19454 | 50 |
IVNS1ABP,RPL27A,NTRK1 |
3.553e-02 | -3.34 | carbohydrate derivative binding | molecular function | GO:0097367 | 2251 | 11 | 18094 | 49 |
BMP2K,CTSS,NTRK1,ITM2B,CSF1R,ENTPD1,GNAI2,HCK,HIPK2,PSAP,SYK |
3.554e-02 | -3.34 | THIOL_PROTEASE_ASN | prosite domains | PS00640 | 10 | 1 | 12186 | 44 |
CTSS |
3.558e-02 | -3.34 | gag-pol (Gag-Pol) | protein interactions | 155348 | 713 | 5 | 19454 | 50 |
RPS3A,RPL14,RPL35,RPL8,RPL18A |
3.575e-02 | -3.33 | lung-carcinoma-large_cell_carcinoma | COSMIC cancer mutations | lung-carcinoma-large_cell_carcinoma | 849 | 6 | 16828 | 49 |
CSF1R,HCK,BMP2K,SYK,NTRK1,HIPK2 |
3.575e-02 | -3.33 | large_cell_carcinoma | COSMIC cancer mutations | large_cell_carcinoma | 849 | 6 | 16828 | 49 |
BMP2K,HIPK2,SYK,HCK,NTRK1,CSF1R |
3.576e-02 | -3.33 | LAMTOR1 (late endosomal/lysosomal adaptor, MAPK and MTOR activator 1) | protein interactions | 55004 | 714 | 5 | 19454 | 50 |
DIAPH2,BMP2K,SPECC1,GAB1,FCHO2 |
3.586e-02 | -3.33 | CD4 (CD4 molecule) | protein interactions | 920 | 116 | 2 | 19454 | 50 |
GNAI2,SYK |
3.589e-02 | -3.33 | plasma membrane raft | cellular component | GO:0044853 | 114 | 2 | 19108 | 50 |
ENTPD1,HCK |
3.593e-02 | -3.33 | skin-upper_leg-malignant_melanoma | COSMIC cancer mutations | skin-upper_leg-malignant_melanoma | 850 | 6 | 16828 | 49 |
ADAM28,SLC13A1,NTRK1,MAN1C1,DCC,ELMO1 |
3.593e-02 | -3.33 | Peptidase_C1 | pfam domains | PF00112 | 13 | 1 | 17795 | 50 |
CTSS |
3.615e-02 | -3.32 | ISG15 (ISG15 ubiquitin like modifier) | protein interactions | 9636 | 487 | 4 | 19454 | 50 |
BMP2K,RPL13A,RPS26,RPL27A |
3.615e-02 | -3.32 | HLA-A (major histocompatibility complex, class I, A) | protein interactions | 3105 | 283 | 3 | 19454 | 50 |
NTRK1,ITM2B,CTSS |
3.615e-02 | -3.32 | FUBP3 (far upstream element binding protein 3) | protein interactions | 8939 | 283 | 3 | 19454 | 50 |
RPS20,RBM47,NTRK1 |
3.634e-02 | -3.31 | tube development | biological process | GO:0035295 | 903 | 6 | 18204 | 50 |
HIPK2,CSF1R,SYK,RPL13A,GAB1,PTPN6 |
3.642e-02 | -3.31 | ABCF3 (ATP binding cassette subfamily F member 3) | protein interactions | 55324 | 117 | 2 | 19454 | 50 |
NTRK1,RPS20 |
3.677e-02 | -3.30 | response to biotic stimulus | biological process | GO:0009607 | 1408 | 8 | 18204 | 50 |
HCK,ITGAX,CD74,RPL13A,SYK,PTPN6,IVNS1ABP,CSF1R |
3.680e-02 | -3.30 | CNOT1 (CCR4-NOT transcription complex subunit 1) | protein interactions | 23019 | 285 | 3 | 19454 | 50 |
NTRK1,RXRA,RPS20 |
3.680e-02 | -3.30 | ATXN2 (ataxin 2) | protein interactions | 6311 | 285 | 3 | 19454 | 50 |
RBM47,RPS20,NTRK1 |
3.699e-02 | -3.30 | POLA1 (DNA polymerase alpha 1, catalytic subunit) | protein interactions | 5422 | 118 | 2 | 19454 | 50 |
RPL36A,NTRK1 |
3.699e-02 | -3.30 | NOL8 (nucleolar protein 8) | protein interactions | 55035 | 118 | 2 | 19454 | 50 |
RPL13A,RPL35 |
3.699e-02 | -3.30 | RAB11FIP1 (RAB11 family interacting protein 1) | protein interactions | 80223 | 118 | 2 | 19454 | 50 |
RPL34,NTRK1 |
3.715e-02 | -3.29 | Ras_G-nucl-exch_fac_CS | interpro domains | IPR019804 | 14 | 1 | 18521 | 50 |
RGL1 |
3.715e-02 | -3.29 | MHD | interpro domains | IPR028565 | 14 | 1 | 18521 | 50 |
FCHO2 |
3.717e-02 | -3.29 | regulation of phosphate metabolic process | biological process | GO:0019220 | 1154 | 7 | 18204 | 50 |
CSF1R,HIPK2,NTRK1,CARD10,CD74,PTPN6,SYK |
3.721e-02 | -3.29 | skin-vulva-malignant_melanoma | COSMIC cancer mutations | skin-vulva-malignant_melanoma | 13 | 1 | 16828 | 49 |
DCC |
3.724e-02 | -3.29 | regulation of leukocyte proliferation | biological process | GO:0070663 | 268 | 3 | 18204 | 50 |
PTPN6,CSF1R,CD74 |
3.727e-02 | -3.29 | Toll-like receptor binding | molecular function | GO:0035325 | 14 | 1 | 18094 | 49 |
SYK |
3.727e-02 | -3.29 | alpha-mannosidase activity | molecular function | GO:0004559 | 14 | 1 | 18094 | 49 |
MAN1C1 |
3.727e-02 | -3.29 | PAPAIN | prints domains | PR00705 | 11 | 1 | 5227 | 18 |
CTSS |
3.732e-02 | -3.29 | regulation of phosphorus metabolic process | biological process | GO:0051174 | 1155 | 7 | 18204 | 50 |
SYK,PTPN6,CD74,CARD10,NTRK1,HIPK2,CSF1R |
3.755e-02 | -3.28 | MAPK1 (mitogen-activated protein kinase 1) | protein interactions | 5594 | 493 | 4 | 19454 | 50 |
NTRK1,RXRA,GAB1,DCC |
3.755e-02 | -3.28 | intracellular membrane-bounded organelle | cellular component | GO:0043231 | 12479 | 39 | 19108 | 50 |
RPL8,HCK,RPL37A,SYK,FCHO2,GNAI2,RAPGEF6,RPL12,RPL36A,RPL35,IVNS1ABP,RPS26,DIAPH2,RPS20,RPS3A,CADPS2,CTSS,RPL34,ARAP1,RPS14,MAN1C1,PTPN6,ITM2B,PDE6D,RBM47,BMP2K,SPECC1,RPL27A,FYB1,PSAP,RXRA,CD74,HIPK2,ITGAX,ADAM28,CSF1R,RPL13A,RPS25,NTRK1 |
3.756e-02 | -3.28 | OXCT1 (3-oxoacid CoA-transferase 1) | protein interactions | 5019 | 119 | 2 | 19454 | 50 |
NTRK1,BMP2K |
3.756e-02 | -3.28 | TALDO1 (transaldolase 1) | protein interactions | 6888 | 119 | 2 | 19454 | 50 |
NTRK1,PDE6D |
3.762e-02 | -3.28 | cytokine receptor binding | molecular function | GO:0005126 | 273 | 3 | 18094 | 49 |
SH2B3,NTRK1,SYK |
3.777e-02 | -3.28 | MAP4 (microtubule associated protein 4) | protein interactions | 4134 | 288 | 3 | 19454 | 50 |
RPS14,NTRK1,RPS20 |
3.779e-02 | -3.28 | UBR5 (ubiquitin protein ligase E3 component n-recognin 5) | protein interactions | 51366 | 494 | 4 | 19454 | 50 |
CD74,RPL35,RPL14,RPL8 |
3.779e-02 | -3.28 | VDAC1 (voltage dependent anion channel 1) | protein interactions | 7416 | 494 | 4 | 19454 | 50 |
CD74,NTRK1,RPL12,RPL35 |
3.779e-02 | -3.28 | regulation of unsaturated fatty acid biosynthetic process | biological process | GO:2001279 | 14 | 1 | 18204 | 50 |
CD74 |
3.779e-02 | -3.28 | Sertoli cell development | biological process | GO:0060009 | 14 | 1 | 18204 | 50 |
NTRK1 |
3.779e-02 | -3.28 | negative regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway | biological process | GO:0106072 | 14 | 1 | 18204 | 50 |
GNAI2 |
3.779e-02 | -3.28 | positive regulation by symbiont of entry into host | biological process | GO:0075294 | 14 | 1 | 18204 | 50 |
CD74 |
3.779e-02 | -3.28 | regulation of podosome assembly | biological process | GO:0071801 | 14 | 1 | 18204 | 50 |
HCK |
3.779e-02 | -3.28 | positive regulation of viral entry into host cell | biological process | GO:0046598 | 14 | 1 | 18204 | 50 |
CD74 |
3.779e-02 | -3.28 | activation of NF-kappaB-inducing kinase activity | biological process | GO:0007250 | 14 | 1 | 18204 | 50 |
CARD10 |
3.779e-02 | -3.28 | nerve growth factor signaling pathway | biological process | GO:0038180 | 14 | 1 | 18204 | 50 |
NTRK1 |
3.779e-02 | -3.28 | negative regulation of adenylate cyclase activity | biological process | GO:0007194 | 14 | 1 | 18204 | 50 |
GNAI2 |
3.779e-02 | -3.28 | peptidyl-tyrosine autophosphorylation | biological process | GO:0038083 | 14 | 1 | 18204 | 50 |
NTRK1 |
3.779e-02 | -3.28 | positive regulation of receptor recycling | biological process | GO:0001921 | 14 | 1 | 18204 | 50 |
ARAP1 |
3.788e-02 | -3.27 | ZNF32 (zinc finger protein 32) | protein interactions | 7580 | 15 | 1 | 19454 | 50 |
CARD10 |
3.788e-02 | -3.27 | UCP3 (uncoupling protein 3) | protein interactions | 7352 | 15 | 1 | 19454 | 50 |
RBM47 |
3.788e-02 | -3.27 | ZNF714 (zinc finger protein 714) | protein interactions | 148206 | 15 | 1 | 19454 | 50 |
RPL27A |
3.788e-02 | -3.27 | DBH (dopamine beta-hydroxylase) | protein interactions | 1621 | 15 | 1 | 19454 | 50 |
NTRK1 |
3.788e-02 | -3.27 | IGSF1 (immunoglobulin superfamily member 1) | protein interactions | 3547 | 15 | 1 | 19454 | 50 |
RPL8 |
3.788e-02 | -3.27 | ADRA2A (adrenoceptor alpha 2A) | protein interactions | 150 | 15 | 1 | 19454 | 50 |
GNAI2 |
3.788e-02 | -3.27 | CASTOR1 (cytosolic arginine sensor for mTORC1 subunit 1) | protein interactions | 652968 | 15 | 1 | 19454 | 50 |
RXRA |
3.797e-02 | -3.27 | PDGFR-beta signaling pathway | Pathway Interaction DB | pdgfrbpathway | 54 | 2 | 2226 | 13 |
HCK,GAB1 |
3.802e-02 | -3.27 | OCLN (occludin) | protein interactions | 100506658 | 495 | 4 | 19454 | 50 |
SPECC1,GAB1,RAPGEF6,FCHO2 |
3.814e-02 | -3.27 | TOMM70 (translocase of outer mitochondrial membrane 70) | protein interactions | 9868 | 120 | 2 | 19454 | 50 |
RPL13A,NTRK1 |
3.814e-02 | -3.27 | HNRNPA1L2 (heterogeneous nuclear ribonucleoprotein A1 like 2) | protein interactions | 144983 | 120 | 2 | 19454 | 50 |
PTPN6,RPS25 |
3.814e-02 | -3.27 | FRS3 (fibroblast growth factor receptor substrate 3) | protein interactions | 10817 | 120 | 2 | 19454 | 50 |
HCK,NTRK1 |
3.814e-02 | -3.27 | CD79B (CD79b molecule) | protein interactions | 974 | 120 | 2 | 19454 | 50 |
PTPN6,SYK |
3.837e-02 | -3.26 | side of membrane | cellular component | GO:0098552 | 715 | 5 | 19108 | 50 |
HCK,CD74,RPS26,GNAI2,ITGAX |
3.843e-02 | -3.26 | RRBP1 (ribosome binding protein 1) | protein interactions | 6238 | 290 | 3 | 19454 | 50 |
NTRK1,DCC,RPL8 |
3.856e-02 | -3.26 | negative regulation of intrinsic apoptotic signaling pathway | biological process | GO:2001243 | 113 | 2 | 18204 | 50 |
IVNS1ABP,CD74 |
3.856e-02 | -3.26 | regulation of regulated secretory pathway | biological process | GO:1903305 | 113 | 2 | 18204 | 50 |
GNAI2,SYK |
3.872e-02 | -3.25 | PRMT3 (protein arginine methyltransferase 3) | protein interactions | 10196 | 121 | 2 | 19454 | 50 |
NTRK1,RPS20 |
3.872e-02 | -3.25 | OSBP (oxysterol binding protein) | protein interactions | 5007 | 121 | 2 | 19454 | 50 |
PSAP,NTRK1 |
3.872e-02 | -3.25 | POLR3B (RNA polymerase III subunit B) | protein interactions | 55703 | 121 | 2 | 19454 | 50 |
NTRK1,CD74 |
3.872e-02 | -3.25 | EIF3J (eukaryotic translation initiation factor 3 subunit J) | protein interactions | 8669 | 121 | 2 | 19454 | 50 |
NTRK1,CD74 |
3.876e-02 | -3.25 | GOPC (golgi associated PDZ and coiled-coil motif containing) | protein interactions | 57120 | 291 | 3 | 19454 | 50 |
NTRK1,CSF1R,HCK |
3.900e-02 | -3.24 | germ_cell_tumour | COSMIC cancer mutations | germ_cell_tumour | 867 | 6 | 16828 | 49 |
NTRK1,HIPK2,HCK,CSF1R,SYK,BMP2K |
3.902e-02 | -3.24 | THIOL_PROTEASE_HIS | prosite domains | PS00639 | 11 | 1 | 12186 | 44 |
CTSS |
3.902e-02 | -3.24 | RECEPTOR_TYR_KIN_II | prosite domains | PS00239 | 11 | 1 | 12186 | 44 |
NTRK1 |
3.902e-02 | -3.24 | ZF_TRAF | prosite domains | PS50145 | 11 | 1 | 12186 | 44 |
PDZRN3 |
3.902e-02 | -3.24 | GBD_FH3 | prosite domains | PS51232 | 11 | 1 | 12186 | 44 |
DIAPH2 |
3.917e-02 | -3.24 | MET receptor recycling | REACTOME pathways | R-HSA-8875656 | 10 | 1 | 10285 | 41 |
GAB1 |
3.917e-02 | -3.24 | Netrin mediated repulsion signals | REACTOME pathways | R-HSA-418886 | 10 | 1 | 10285 | 41 |
DCC |
3.917e-02 | -3.24 | Role of second messengers in netrin-1 signaling | REACTOME pathways | R-HSA-418890 | 10 | 1 | 10285 | 41 |
DCC |
3.917e-02 | -3.24 | Signaling by FGFR3 fusions in cancer | REACTOME pathways | R-HSA-8853334 | 10 | 1 | 10285 | 41 |
GAB1 |
3.918e-02 | -3.24 | icosanoid metabolic process | biological process | GO:0006690 | 114 | 2 | 18204 | 50 |
CD74,SYK |
3.924e-02 | -3.24 | AR (androgen receptor) | protein interactions | 367 | 983 | 6 | 19454 | 50 |
RPL18A,HCK,HIPK2,SYK,DCC,RPL27A |
3.930e-02 | -3.24 | OGA (O-GlcNAcase) | protein interactions | 10724 | 122 | 2 | 19454 | 50 |
NTRK1,PSAP |
3.935e-02 | -3.24 | TMPO (thymopoietin) | protein interactions | 7112 | 733 | 5 | 19454 | 50 |
RPL12,RPL8,RPL35,RPS3A,NTRK1 |
3.941e-02 | -3.23 | SQSTM1 (sequestosome 1) | protein interactions | 8878 | 984 | 6 | 19454 | 50 |
GNAI2,RPL12,RXRA,RPS26,RPL37A,NTRK1 |
3.947e-02 | -3.23 | TUBA4A (tubulin alpha 4a) | protein interactions | 7277 | 501 | 4 | 19454 | 50 |
RPS3A,SYK,RPS14,GNAI2 |
3.975e-02 | -3.23 | FH2_Formin_sf | interpro domains | IPR042201 | 15 | 1 | 18521 | 50 |
DIAPH2 |
3.975e-02 | -3.23 | FH2_Formin | interpro domains | IPR015425 | 15 | 1 | 18521 | 50 |
DIAPH2 |
3.988e-02 | -3.22 | mannosidase activity | molecular function | GO:0015923 | 15 | 1 | 18094 | 49 |
MAN1C1 |
3.988e-02 | -3.22 | nuclear vitamin D receptor binding | molecular function | GO:0042809 | 15 | 1 | 18094 | 49 |
RXRA |
3.988e-02 | -3.22 | ERO1A (endoplasmic reticulum oxidoreductase 1 alpha) | protein interactions | 30001 | 123 | 2 | 19454 | 50 |
NTRK1,CTSS |
3.988e-02 | -3.22 | NAMPT (nicotinamide phosphoribosyltransferase) | protein interactions | 10135 | 123 | 2 | 19454 | 50 |
NTRK1,CTSS |
3.988e-02 | -3.22 | PNO1 (partner of NOB1 homolog) | protein interactions | 56902 | 123 | 2 | 19454 | 50 |
RPS26,RPS20 |
3.988e-02 | -3.22 | STAT5B (signal transducer and activator of transcription 5B) | protein interactions | 6777 | 123 | 2 | 19454 | 50 |
NTRK1,PTPN6 |
3.990e-02 | -3.22 | cytoplasmic vesicle membrane | cellular component | GO:0030659 | 1230 | 7 | 19108 | 50 |
PSAP,NTRK1,PDE6D,CADPS2,ITGAX,ITM2B,CD74 |
4.035e-02 | -3.21 | BGLAP (bone gamma-carboxyglutamate protein) | protein interactions | 632 | 16 | 1 | 19454 | 50 |
CTSS |
4.035e-02 | -3.21 | Evpl (envoplakin) | protein interactions | 14027 | 16 | 1 | 19454 | 50 |
IVNS1ABP |
4.035e-02 | -3.21 | SYT4 (synaptotagmin 4) | protein interactions | 6860 | 16 | 1 | 19454 | 50 |
NTRK1 |
4.035e-02 | -3.21 | BTN1A1 (butyrophilin subfamily 1 member A1) | protein interactions | 696 | 16 | 1 | 19454 | 50 |
NTRK1 |
4.035e-02 | -3.21 | CASTOR2 (cytosolic arginine sensor for mTORC1 subunit 2) | protein interactions | 729438 | 16 | 1 | 19454 | 50 |
RXRA |
4.035e-02 | -3.21 | TAMALIN (trafficking regulator and scaffold protein tamalin) | protein interactions | 160622 | 16 | 1 | 19454 | 50 |
SYK |
4.035e-02 | -3.21 | SLCO6A1 (solute carrier organic anion transporter family member 6A1) | protein interactions | 133482 | 16 | 1 | 19454 | 50 |
RPL14 |
4.035e-02 | -3.21 | TNFRSF25 (TNF receptor superfamily member 25) | protein interactions | 8718 | 16 | 1 | 19454 | 50 |
PTPN6 |
4.035e-02 | -3.21 | RGS16 (regulator of G protein signaling 16) | protein interactions | 6004 | 16 | 1 | 19454 | 50 |
GNAI2 |
4.035e-02 | -3.21 | FZD4 (frizzled class receptor 4) | protein interactions | 8322 | 16 | 1 | 19454 | 50 |
PDZRN3 |
4.035e-02 | -3.21 | ZSCAN4 (zinc finger and SCAN domain containing 4) | protein interactions | 201516 | 16 | 1 | 19454 | 50 |
HCK |
4.043e-02 | -3.21 | establishment of endothelial intestinal barrier | biological process | GO:0090557 | 15 | 1 | 18204 | 50 |
RAPGEF6 |
4.043e-02 | -3.21 | detection of mechanical stimulus involved in sensory perception of pain | biological process | GO:0050966 | 15 | 1 | 18204 | 50 |
NTRK1 |
4.043e-02 | -3.21 | collagen-activated signaling pathway | biological process | GO:0038065 | 15 | 1 | 18204 | 50 |
SYK |
4.043e-02 | -3.21 | negative regulation of immunoglobulin mediated immune response | biological process | GO:0002890 | 15 | 1 | 18204 | 50 |
PTPN6 |
4.043e-02 | -3.21 | negative regulation of B cell mediated immunity | biological process | GO:0002713 | 15 | 1 | 18204 | 50 |
PTPN6 |
4.043e-02 | -3.21 | negative regulation of B cell apoptotic process | biological process | GO:0002903 | 15 | 1 | 18204 | 50 |
CD74 |
4.043e-02 | -3.21 | positive regulation of granulocyte macrophage colony-stimulating factor production | biological process | GO:0032725 | 15 | 1 | 18204 | 50 |
SYK |
4.043e-02 | -3.21 | negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator | biological process | GO:1902166 | 15 | 1 | 18204 | 50 |
CD74 |
4.043e-02 | -3.21 | negative regulation of cyclase activity | biological process | GO:0031280 | 15 | 1 | 18204 | 50 |
GNAI2 |
4.043e-02 | -3.21 | neutrophil activation involved in immune response | biological process | GO:0002283 | 15 | 1 | 18204 | 50 |
SYK |
4.043e-02 | -3.21 | neurotrophin TRK receptor signaling pathway | biological process | GO:0048011 | 15 | 1 | 18204 | 50 |
NTRK1 |
4.043e-02 | -3.21 | negative regulation of DNA damage response, signal transduction by p53 class mediator | biological process | GO:0043518 | 15 | 1 | 18204 | 50 |
CD74 |
4.043e-02 | -3.21 | protein deglycosylation | biological process | GO:0006517 | 15 | 1 | 18204 | 50 |
MAN1C1 |
4.043e-02 | -3.21 | macrophage chemotaxis | biological process | GO:0048246 | 15 | 1 | 18204 | 50 |
RPL13A |
4.043e-02 | -3.21 | dense core granule localization | biological process | GO:0032253 | 15 | 1 | 18204 | 50 |
CADPS2 |
4.043e-02 | -3.21 | positive regulation of monocyte chemotactic protein-1 production | biological process | GO:0071639 | 15 | 1 | 18204 | 50 |
SYK |
4.045e-02 | -3.21 | APEX1 (apurinic/apyrimidinic endodeoxyribonuclease 1) | protein interactions | 328 | 1256 | 7 | 19454 | 50 |
RPL14,BMP2K,RAPGEF6,GAB1,NTRK1,RPS20,GNAI2 |
4.047e-02 | -3.21 | AGK (acylglycerol kinase) | protein interactions | 55750 | 124 | 2 | 19454 | 50 |
NTRK1,HCK |
4.047e-02 | -3.21 | THOC5 (THO complex subunit 5) | protein interactions | 8563 | 124 | 2 | 19454 | 50 |
CSF1R,RPL27A |
4.047e-02 | -3.21 | DAB2 (DAB adaptor protein 2) | protein interactions | 1601 | 124 | 2 | 19454 | 50 |
FCHO2,BMP2K |
4.066e-02 | -3.20 | kidney-carcinoma-papillary_renal_cell_carcinoma | COSMIC cancer mutations | kidney-carcinoma-papillary_renal_cell_carcinoma | 6364 | 25 | 16828 | 49 |
RPL12,ELMO1,RPL8,RBM47,GNAI2,SYK,CSF1R,ARAP1,HIPK2,ITM2B,RPL37A,NTRK1,FCHO2,ITGAX,CADPS2,HCK,DCC,PDZRN3,SLC13A1,BMP2K,RGL1,CARD10,SH2B3,ADAM28,RPS14 |
4.066e-02 | -3.20 | papillary_renal_cell_carcinoma | COSMIC cancer mutations | papillary_renal_cell_carcinoma | 6364 | 25 | 16828 | 49 |
ADAM28,RPS14,BMP2K,SH2B3,CARD10,RGL1,DCC,PDZRN3,SLC13A1,ITGAX,FCHO2,HCK,CADPS2,RPL37A,HIPK2,ITM2B,NTRK1,GNAI2,RBM47,SYK,ARAP1,CSF1R,RPL12,ELMO1,RPL8 |
4.079e-02 | -3.20 | RBM4 (RNA binding motif protein 4) | protein interactions | 5936 | 297 | 3 | 19454 | 50 |
RPL14,RPL18A,NTRK1 |
4.080e-02 | -3.20 | regulation of GTPase activity | biological process | GO:0043087 | 278 | 3 | 18204 | 50 |
ARAP1,RAPGEF6,NTRK1 |
4.080e-02 | -3.20 | actin filament organization | biological process | GO:0007015 | 278 | 3 | 18204 | 50 |
ARAP1,ELMO1,DIAPH2 |
4.105e-02 | -3.19 | developmental process | biological process | GO:0032502 | 5716 | 22 | 18204 | 50 |
HIPK2,RBM47,PSAP,HCK,ITM2B,NTRK1,GAB1,SYK,ITGAX,DCC,RPS3A,RAPGEF6,RPS14,SH2B3,PTPN6,DIAPH2,CSF1R,ADAM28,RPL13A,CD74,RXRA,SPECC1 |
4.107e-02 | -3.19 | cytoplasmic side of endoplasmic reticulum membrane | cellular component | GO:0098554 | 16 | 1 | 19108 | 50 |
RPS26 |
4.113e-02 | -3.19 | MRPS35 (mitochondrial ribosomal protein S35) | protein interactions | 60488 | 298 | 3 | 19454 | 50 |
NTRK1,RPL27A,RPL35 |
4.115e-02 | -3.19 | small GTPase binding | molecular function | GO:0031267 | 283 | 3 | 18094 | 49 |
PDE6D,RAPGEF6,DIAPH2 |
4.117e-02 | -3.19 | positive regulation of leukocyte cell-cell adhesion | biological process | GO:1903039 | 279 | 3 | 18204 | 50 |
CD74,PTPN6,SYK |
4.134e-02 | -3.19 | FH2 | pfam domains | PF02181 | 15 | 1 | 17795 | 50 |
DIAPH2 |
4.135e-02 | -3.19 | lymphocyte activation | biological process | GO:0046649 | 476 | 4 | 18204 | 50 |
SYK,NTRK1,PTPN6,CD74 |
4.147e-02 | -3.18 | MRPS31 (mitochondrial ribosomal protein S31) | protein interactions | 10240 | 299 | 3 | 19454 | 50 |
RPL27A,SYK,RPL35 |
4.166e-02 | -3.18 | TARBP2 (TARBP2 subunit of RISC loading complex) | protein interactions | 6895 | 126 | 2 | 19454 | 50 |
RPL13A,RPL35 |
4.166e-02 | -3.18 | INSIG1 (insulin induced gene 1) | protein interactions | 3638 | 126 | 2 | 19454 | 50 |
RPL12,CADPS2 |
4.170e-02 | -3.18 | regulation of receptor-mediated endocytosis | biological process | GO:0048259 | 118 | 2 | 18204 | 50 |
BMP2K,SYK |
4.196e-02 | -3.17 | ATP binding | molecular function | GO:0005524 | 1467 | 8 | 18094 | 49 |
HIPK2,SYK,HCK,ITM2B,ENTPD1,CSF1R,BMP2K,NTRK1 |
4.216e-02 | -3.17 | ARRB1 (arrestin beta 1) | protein interactions | 408 | 301 | 3 | 19454 | 50 |
HCK,RPL8,RPS3A |
4.219e-02 | -3.17 | HGS (hepatocyte growth factor-regulated tyrosine kinase substrate) | protein interactions | 9146 | 512 | 4 | 19454 | 50 |
SYK,CSF1R,RPS3A,NTRK1 |
4.226e-02 | -3.16 | NOM1 (nucleolar protein with MIF4G domain 1) | protein interactions | 64434 | 127 | 2 | 19454 | 50 |
NTRK1,RPL14 |
4.226e-02 | -3.16 | RRM1 (ribonucleotide reductase catalytic subunit M1) | protein interactions | 6240 | 127 | 2 | 19454 | 50 |
RPL35,NTRK1 |
4.228e-02 | -3.16 | homeostasis of number of cells | biological process | GO:0048872 | 282 | 3 | 18204 | 50 |
RPS14,HIPK2,SH2B3 |
4.235e-02 | -3.16 | Integrin_alpha_Ig-like_1 | interpro domains | IPR013649 | 16 | 1 | 18521 | 50 |
ITGAX |
4.235e-02 | -3.16 | Integrin_alpha_C_CS | interpro domains | IPR018184 | 16 | 1 | 18521 | 50 |
ITGAX |
4.235e-02 | -3.16 | Gprotein_alpha_su | interpro domains | IPR001019 | 16 | 1 | 18521 | 50 |
GNAI2 |
4.235e-02 | -3.16 | Disintegrin_CS | interpro domains | IPR018358 | 16 | 1 | 18521 | 50 |
ADAM28 |
4.235e-02 | -3.16 | GproteinA_insert | interpro domains | IPR011025 | 16 | 1 | 18521 | 50 |
GNAI2 |
4.248e-02 | -3.16 | CARD domain binding | molecular function | GO:0050700 | 16 | 1 | 18094 | 49 |
CARD10 |
4.248e-02 | -3.16 | sulfate transmembrane transporter activity | molecular function | GO:0015116 | 16 | 1 | 18094 | 49 |
SLC13A1 |
4.251e-02 | -3.16 | TP63 (tumor protein p63) | protein interactions | 8626 | 302 | 3 | 19454 | 50 |
HIPK2,RPL12,RPL13A |
4.251e-02 | -3.16 | NOLC1 (nucleolar and coiled-body phosphoprotein 1) | protein interactions | 9221 | 302 | 3 | 19454 | 50 |
RPL18A,SYK,RPS14 |
4.270e-02 | -3.15 | RBM14 (RNA binding motif protein 14) | protein interactions | 10432 | 514 | 4 | 19454 | 50 |
RPL14,RPS26,RPS20,NTRK1 |
4.271e-02 | -3.15 | regulation of response to stimulus | biological process | GO:0048583 | 4104 | 17 | 18204 | 50 |
CTSS,SYK,CD74,RXRA,FYB1,NTRK1,BMP2K,ARAP1,CSF1R,IVNS1ABP,PTPN6,GNAI2,HCK,RPS20,HIPK2,RBM47,SH2B3 |
4.282e-02 | -3.15 | STRA6 (signaling receptor and transporter of retinol STRA6) | protein interactions | 64220 | 17 | 1 | 19454 | 50 |
NTRK1 |
4.282e-02 | -3.15 | ZNF708 (zinc finger protein 708) | protein interactions | 7562 | 17 | 1 | 19454 | 50 |
RPL27A |
4.282e-02 | -3.15 | MRAS (muscle RAS oncogene homolog) | protein interactions | 22808 | 17 | 1 | 19454 | 50 |
RAPGEF6 |
4.282e-02 | -3.15 | RGMA (repulsive guidance molecule BMP co-receptor a) | protein interactions | 56963 | 17 | 1 | 19454 | 50 |
HIPK2 |
4.282e-02 | -3.15 | ARL4A (ADP ribosylation factor like GTPase 4A) | protein interactions | 10124 | 17 | 1 | 19454 | 50 |
ELMO1 |
4.282e-02 | -3.15 | ZNF12 (zinc finger protein 12) | protein interactions | 7559 | 17 | 1 | 19454 | 50 |
CARD10 |
4.282e-02 | -3.15 | SLAMF6 (SLAM family member 6) | protein interactions | 114836 | 17 | 1 | 19454 | 50 |
PTPN6 |
4.282e-02 | -3.15 | FOXD4L3 (forkhead box D4 like 3) | protein interactions | 286380 | 17 | 1 | 19454 | 50 |
CARD10 |
4.286e-02 | -3.15 | ATF7IP (activating transcription factor 7 interacting protein) | protein interactions | 55729 | 128 | 2 | 19454 | 50 |
RPS3A,RPL8 |
4.286e-02 | -3.15 | ZKSCAN8 (zinc finger with KRAB and SCAN domains 8) | protein interactions | 7745 | 128 | 2 | 19454 | 50 |
RPL14,RPS3A |
4.286e-02 | -3.15 | FARP1 (FERM, ARH/RhoGEF and pleckstrin domain protein 1) | protein interactions | 10160 | 128 | 2 | 19454 | 50 |
NTRK1,RBM47 |
4.296e-02 | -3.15 | phospholipid binding | molecular function | GO:0005543 | 489 | 4 | 18094 | 49 |
FCHO2,PSAP,RAPGEF6,ARAP1 |
4.297e-02 | -3.15 | RAC1 (Rac family small GTPase 1) | protein interactions | 5879 | 1005 | 6 | 19454 | 50 |
ARAP1,DIAPH2,FCHO2,GAB1,SPECC1,GNAI2 |
4.299e-02 | -3.15 | regulation of cytokine production involved in immune response | biological process | GO:0002718 | 120 | 2 | 18204 | 50 |
CD74,SYK |
4.301e-02 | -3.15 | MET activates RAP1 and RAC1 | REACTOME pathways | R-HSA-8875555 | 11 | 1 | 10285 | 41 |
GAB1 |
4.301e-02 | -3.15 | DSCAM interactions | REACTOME pathways | R-HSA-376172 | 11 | 1 | 10285 | 41 |
DCC |
4.301e-02 | -3.15 | Ligand-independent caspase activation via DCC | REACTOME pathways | R-HSA-418889 | 11 | 1 | 10285 | 41 |
DCC |
4.301e-02 | -3.15 | Import of palmitoyl-CoA into the mitochondrial matrix | REACTOME pathways | R-HSA-200425 | 11 | 1 | 10285 | 41 |
RXRA |
4.301e-02 | -3.15 | Signaling by FGFR4 in disease | REACTOME pathways | R-HSA-5655291 | 11 | 1 | 10285 | 41 |
GAB1 |
4.307e-02 | -3.14 | maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) | biological process | GO:0000463 | 16 | 1 | 18204 | 50 |
RPL35 |
4.307e-02 | -3.14 | neutrophil homeostasis | biological process | GO:0001780 | 16 | 1 | 18204 | 50 |
SH2B3 |
4.307e-02 | -3.14 | sulfate transmembrane transport | biological process | GO:1902358 | 16 | 1 | 18204 | 50 |
SLC13A1 |
4.307e-02 | -3.14 | positive regulation of B cell differentiation | biological process | GO:0045579 | 16 | 1 | 18204 | 50 |
SYK |
4.310e-02 | -3.14 | vesicle membrane | cellular component | GO:0012506 | 1251 | 7 | 19108 | 50 |
CD74,CADPS2,ITGAX,ITM2B,PDE6D,PSAP,NTRK1 |
4.311e-02 | -3.14 | human chr18q21.2 | chromosome location | human chr18q21.2 | 23 | 1 | 26134 | 50 |
DCC |
4.317e-02 | -3.14 | SH3 domain binding | molecular function | GO:0017124 | 122 | 2 | 18094 | 49 |
ELMO1,PTPN6 |
4.321e-02 | -3.14 | SH3KBP1 (SH3 domain containing kinase binding protein 1) | protein interactions | 30011 | 304 | 3 | 19454 | 50 |
IVNS1ABP,HCK,ARAP1 |
4.325e-02 | -3.14 | cell adhesion | biological process | GO:0007155 | 942 | 6 | 18204 | 50 |
ITGAX,ENTPD1,HCK,SYK,PTPN6,DCC |
4.329e-02 | -3.14 | Pept_C1 | smart domains | SM00645 | 13 | 1 | 9717 | 33 |
CTSS |
4.346e-02 | -3.14 | RNGTT (RNA guanylyltransferase and 5'-phosphatase) | protein interactions | 8732 | 129 | 2 | 19454 | 50 |
RPL37A,NTRK1 |
4.346e-02 | -3.14 | PNKP (polynucleotide kinase 3'-phosphatase) | protein interactions | 11284 | 129 | 2 | 19454 | 50 |
CARD10,NTRK1 |
4.346e-02 | -3.14 | ALDH2 (aldehyde dehydrogenase 2 family member) | protein interactions | 217 | 129 | 2 | 19454 | 50 |
RPL13A,NTRK1 |
4.346e-02 | -3.14 | Lima1 (LIM domain and actin binding 1) | protein interactions | 65970 | 129 | 2 | 19454 | 50 |
FCHO2,SPECC1 |
4.352e-02 | -3.13 | skin-chest-malignant_melanoma | COSMIC cancer mutations | skin-chest-malignant_melanoma | 114 | 2 | 16828 | 49 |
DCC,NTRK1 |
4.358e-02 | -3.13 | MHC class II protein complex | cellular component | GO:0042613 | 17 | 1 | 19108 | 50 |
CD74 |
4.364e-02 | -3.13 | positive regulation of T cell differentiation | biological process | GO:0045582 | 121 | 2 | 18204 | 50 |
CD74,SYK |
4.368e-02 | -3.13 | pleura-mesothelioma | COSMIC cancer mutations | pleura-mesothelioma | 4189 | 18 | 16828 | 49 |
PTPN6,PDZRN3,RPL36A,SYK,GNAI2,BMP2K,CSF1R,RGL1,CARD10,HIPK2,GAB1,NTRK1,RAPGEF6,ITGAX,DIAPH2,SPECC1,HCK,ADAM28 |
4.390e-02 | -3.13 | DISINTEGRIN | prints domains | PR00289 | 13 | 1 | 5227 | 18 |
ADAM28 |
4.392e-02 | -3.13 | HDGF (heparin binding growth factor) | protein interactions | 3068 | 306 | 3 | 19454 | 50 |
RPL34,RPL35,NTRK1 |
4.404e-02 | -3.12 | G-alpha | pfam domains | PF00503 | 16 | 1 | 17795 | 50 |
GNAI2 |
4.404e-02 | -3.12 | Integrin_A_Ig_1 | pfam domains | PF08441 | 16 | 1 | 17795 | 50 |
ITGAX |
4.429e-02 | -3.12 | regulation of leukocyte chemotaxis | biological process | GO:0002688 | 122 | 2 | 18204 | 50 |
CSF1R,CD74 |
4.468e-02 | -3.11 | MRPL51 (mitochondrial ribosomal protein L51) | protein interactions | 51258 | 131 | 2 | 19454 | 50 |
RPL27A,RPL13A |
4.493e-02 | -3.10 | Thyroglobulin_1_sf | interpro domains | IPR036857 | 17 | 1 | 18521 | 50 |
CD74 |
4.493e-02 | -3.10 | Thyroglobulin_1 | interpro domains | IPR000716 | 17 | 1 | 18521 | 50 |
CD74 |
4.499e-02 | -3.10 | TGFB1 (transforming growth factor beta 1) | protein interactions | 7040 | 309 | 3 | 19454 | 50 |
RPL27A,RPS3A,RPL12 |
4.499e-02 | -3.10 | AFDN (afadin, adherens junction formation factor) | protein interactions | 4301 | 309 | 3 | 19454 | 50 |
GAB1,SPECC1,NTRK1 |
4.503e-02 | -3.10 | SF3B3 (splicing factor 3b subunit 3) | protein interactions | 23450 | 523 | 4 | 19454 | 50 |
NTRK1,RPL18A,HCK,CADPS2 |
4.507e-02 | -3.10 | ephrin receptor activity | molecular function | GO:0005003 | 17 | 1 | 18094 | 49 |
NTRK1 |
4.507e-02 | -3.10 | nucleoside diphosphate phosphatase activity | molecular function | GO:0017110 | 17 | 1 | 18094 | 49 |
ENTPD1 |
4.507e-02 | -3.10 | transmembrane receptor protein tyrosine phosphatase activity | molecular function | GO:0005001 | 17 | 1 | 18094 | 49 |
PTPN6 |
4.507e-02 | -3.10 | transmembrane receptor protein tyrosine kinase adaptor activity | molecular function | GO:0005068 | 17 | 1 | 18094 | 49 |
SH2B3 |
4.507e-02 | -3.10 | transmembrane receptor protein phosphatase activity | molecular function | GO:0019198 | 17 | 1 | 18094 | 49 |
PTPN6 |
4.509e-02 | -3.10 | protein tyrosine kinase binding | molecular function | GO:1990782 | 125 | 2 | 18094 | 49 |
ITGAX,SH2B3 |
4.529e-02 | -3.09 | ZNF100 (zinc finger protein 100) | protein interactions | 163227 | 18 | 1 | 19454 | 50 |
RPL27A |
4.529e-02 | -3.09 | Ccdc77 (coiled-coil domain containing 77) | protein interactions | 67200 | 18 | 1 | 19454 | 50 |
RPL35 |
4.529e-02 | -3.09 | Chmp6 (charged multivesicular body protein 6) | protein interactions | 208092 | 18 | 1 | 19454 | 50 |
PTPN6 |
4.529e-02 | -3.09 | GNG7 (G protein subunit gamma 7) | protein interactions | 2788 | 18 | 1 | 19454 | 50 |
GNAI2 |
4.529e-02 | -3.09 | CLCN5 (chloride voltage-gated channel 5) | protein interactions | 1184 | 18 | 1 | 19454 | 50 |
NTRK1 |
4.529e-02 | -3.09 | LHCGR (luteinizing hormone/choriogonadotropin receptor) | protein interactions | 3973 | 18 | 1 | 19454 | 50 |
GNAI2 |
4.529e-02 | -3.09 | CYP2E1 (cytochrome P450 family 2 subfamily E member 1) | protein interactions | 1571 | 18 | 1 | 19454 | 50 |
RPL13A |
4.529e-02 | -3.09 | TM4SF20 (transmembrane 4 L six family member 20) | protein interactions | 79853 | 18 | 1 | 19454 | 50 |
CD74 |
4.529e-02 | -3.09 | C1orf116 (chromosome 1 open reading frame 116) | protein interactions | 79098 | 18 | 1 | 19454 | 50 |
RPL14 |
4.529e-02 | -3.09 | GRK3 (G protein-coupled receptor kinase 3) | protein interactions | 157 | 18 | 1 | 19454 | 50 |
NTRK1 |
4.529e-02 | -3.09 | NAALADL2 (N-acetylated alpha-linked acidic dipeptidase like 2) | protein interactions | 254827 | 18 | 1 | 19454 | 50 |
ITM2B |
4.529e-02 | -3.09 | Numb (NUMB endocytic adaptor protein) | protein interactions | 18222 | 18 | 1 | 19454 | 50 |
BMP2K |
4.529e-02 | -3.09 | Fbxl16 (F-box and leucine-rich repeat protein 16) | protein interactions | 214931 | 18 | 1 | 19454 | 50 |
RPL35 |
4.529e-02 | -3.09 | FRMD8 (FERM domain containing 8) | protein interactions | 83786 | 18 | 1 | 19454 | 50 |
RPS14 |
4.530e-02 | -3.09 | YARS1 (tyrosyl-tRNA synthetase 1) | protein interactions | 8565 | 132 | 2 | 19454 | 50 |
NTRK1,CTSS |
4.530e-02 | -3.09 | lymphocyte differentiation | biological process | GO:0030098 | 290 | 3 | 18204 | 50 |
NTRK1,SYK,CD74 |
4.535e-02 | -3.09 | C11orf52 (chromosome 11 open reading frame 52) | protein interactions | 91894 | 310 | 3 | 19454 | 50 |
FCHO2,SPECC1,GAB1 |
4.535e-02 | -3.09 | HNRNPAB (heterogeneous nuclear ribonucleoprotein A/B) | protein interactions | 3182 | 310 | 3 | 19454 | 50 |
NTRK1,RPS3A,IVNS1ABP |
4.560e-02 | -3.09 | regulation of ossification | biological process | GO:0030278 | 124 | 2 | 18204 | 50 |
RXRA,BMP2K |
4.561e-02 | -3.09 | normal | COSMIC cancer mutations | normal | 16 | 1 | 16828 | 49 |
CSF1R |
4.570e-02 | -3.09 | microvillus assembly | biological process | GO:0030033 | 17 | 1 | 18204 | 50 |
RAPGEF6 |
4.570e-02 | -3.09 | protein trimerization | biological process | GO:0070206 | 17 | 1 | 18204 | 50 |
CD74 |
4.570e-02 | -3.09 | ribosomal small subunit assembly | biological process | GO:0000028 | 17 | 1 | 18204 | 50 |
RPS14 |
4.570e-02 | -3.09 | sulfate transport | biological process | GO:0008272 | 17 | 1 | 18204 | 50 |
SLC13A1 |
4.570e-02 | -3.09 | regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator | biological process | GO:1902165 | 17 | 1 | 18204 | 50 |
CD74 |
4.570e-02 | -3.09 | nuclear body organization | biological process | GO:0030575 | 17 | 1 | 18204 | 50 |
HIPK2 |
4.570e-02 | -3.09 | monocyte differentiation | biological process | GO:0030224 | 17 | 1 | 18204 | 50 |
CSF1R |
4.570e-02 | -3.09 | negative regulation of humoral immune response | biological process | GO:0002921 | 17 | 1 | 18204 | 50 |
PTPN6 |
4.570e-02 | -3.09 | response to hepatocyte growth factor | biological process | GO:0035728 | 17 | 1 | 18204 | 50 |
GAB1 |
4.573e-02 | -3.09 | haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-mantle_cell_lymphoma | COSMIC cancer mutations | haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-mantle_cell_lymphoma | 2737 | 13 | 16828 | 49 |
MAN1C1,GAB1,HIPK2,NTRK1,DIAPH2,CADPS2,RPL12,DCC,ELMO1,SLC13A1,PDZRN3,RGL1,PDE6D |
4.585e-02 | -3.08 | S1P5 pathway | Pathway Interaction DB | s1p_s1p5_pathway | 8 | 1 | 2226 | 13 |
GNAI2 |
4.591e-02 | -3.08 | PLAUR (plasminogen activator, urokinase receptor) | protein interactions | 5329 | 133 | 2 | 19454 | 50 |
PSAP,HCK |
4.591e-02 | -3.08 | POLE (DNA polymerase epsilon, catalytic subunit) | protein interactions | 5426 | 133 | 2 | 19454 | 50 |
NTRK1,RPL36A |
4.591e-02 | -3.08 | GTF2F2 (general transcription factor IIF subunit 2) | protein interactions | 2963 | 133 | 2 | 19454 | 50 |
NTRK1,RPL27A |
4.591e-02 | -3.08 | GABRA1 (gamma-aminobutyric acid type A receptor subunit alpha1) | protein interactions | 2554 | 133 | 2 | 19454 | 50 |
RPL35,RPL27A |
4.591e-02 | -3.08 | TRIM56 (tripartite motif containing 56) | protein interactions | 81844 | 133 | 2 | 19454 | 50 |
RPL13A,RPL14 |
4.591e-02 | -3.08 | VTA1 (vesicle trafficking 1) | protein interactions | 51534 | 133 | 2 | 19454 | 50 |
NTRK1,IVNS1ABP |
4.605e-02 | -3.08 | TCR signaling in naive CD4+ T cells | Pathway Interaction DB | tcr_pathway | 60 | 2 | 2226 | 13 |
PTPN6,FYB1 |
4.607e-02 | -3.08 | PRKCI (protein kinase C iota) | protein interactions | 5584 | 312 | 3 | 19454 | 50 |
GAB1,NTRK1,RPL27A |
4.613e-02 | -3.08 | PDZ | pfam domains | PF00595 | 122 | 2 | 17795 | 50 |
PDZRN3,RAPGEF6 |
4.644e-02 | -3.07 | ECPAS (Ecm29 proteasome adaptor and scaffold) | protein interactions | 23392 | 313 | 3 | 19454 | 50 |
GNAI2,NTRK1,RPS26 |
4.644e-02 | -3.07 | KBTBD4 (kelch repeat and BTB domain containing 4) | protein interactions | 55709 | 313 | 3 | 19454 | 50 |
RPS14,RPL34,RPL13A |
4.646e-02 | -3.07 | negative regulation of defense response | biological process | GO:0031348 | 293 | 3 | 18204 | 50 |
HCK,PTPN6,SYK |
4.652e-02 | -3.07 | regulation of localization | biological process | GO:0032879 | 2028 | 10 | 18204 | 50 |
CADPS2,CTSS,PTPN6,GNAI2,SYK,CD74,RXRA,HCK,CARD10,BMP2K |
4.653e-02 | -3.07 | MDH1 (malate dehydrogenase 1) | protein interactions | 4190 | 134 | 2 | 19454 | 50 |
NTRK1,CTSS |
4.668e-02 | -3.06 | fibrous_tissue_and_uncertain_origin | COSMIC cancer mutations | fibrous_tissue_and_uncertain_origin | 277 | 3 | 16828 | 49 |
HIPK2,CSF1R,CARD10 |
4.672e-02 | -3.06 | actin cytoskeleton | cellular component | GO:0015629 | 520 | 4 | 19108 | 50 |
FYB1,DIAPH2,SPECC1,HCK |
4.673e-02 | -3.06 | Thyroglobulin_1 | pfam domains | PF00086 | 17 | 1 | 17795 | 50 |
CD74 |
4.680e-02 | -3.06 | ELOB (elongin B) | protein interactions | 6923 | 314 | 3 | 19454 | 50 |
PSAP,RPS20,DIAPH2 |
4.683e-02 | -3.06 | Physiological factors | REACTOME pathways | R-HSA-5578768 | 12 | 1 | 10285 | 41 |
HIPK2 |
4.683e-02 | -3.06 | Endosomal/Vacuolar pathway | REACTOME pathways | R-HSA-1236977 | 12 | 1 | 10285 | 41 |
CTSS |
4.683e-02 | -3.06 | PECAM1 interactions | REACTOME pathways | R-HSA-210990 | 12 | 1 | 10285 | 41 |
PTPN6 |
4.716e-02 | -3.05 | SEL1L (SEL1L adaptor subunit of SYVN1 ubiquitin ligase) | protein interactions | 6400 | 135 | 2 | 19454 | 50 |
CTSS,NTRK1 |
4.716e-02 | -3.05 | EML4 (EMAP like 4) | protein interactions | 27436 | 135 | 2 | 19454 | 50 |
RPS3A,NTRK1 |
4.717e-02 | -3.05 | STAT1 (signal transducer and activator of transcription 1) | protein interactions | 6772 | 315 | 3 | 19454 | 50 |
SYK,NTRK1,RXRA |
4.717e-02 | -3.05 | FLT3 (fms related receptor tyrosine kinase 3) | protein interactions | 2322 | 315 | 3 | 19454 | 50 |
HCK,DCC,PTPN6 |
4.717e-02 | -3.05 | DARS1 (aspartyl-tRNA synthetase 1) | protein interactions | 1615 | 315 | 3 | 19454 | 50 |
RPL27A,NTRK1,PTPN6 |
4.722e-02 | -3.05 | central_nervous_system-brain-glioma-astrocytoma_Grade_IV | COSMIC cancer mutations | central_nervous_system-brain-glioma-astrocytoma_Grade_IV | 15813 | 49 | 16828 | 49 |
PDZRN3,RPS3A,PSAP,RPS25,SH2B3,CARD10,RPL13A,RXRA,SPECC1,RPS26,ENTPD1,RPL14,RPL36A,ELMO1,RPL12,CD74,RPL34,SYK,GNAI2,RBM47,NTRK1,HIPK2,ITM2B,RPL37A,GAB1,CTSS,ITGAX,DIAPH2,FCHO2,SLC13A1,RPS20,DCC,RGL1,BMP2K,RAPGEF6,MAN1C1,RPS14,ADAM28,RPL8,RPL18A,PTPN6,PDE6D,ARAP1,CSF1R,RPL27A,RPL35,HCK,CADPS2,IVNS1ABP |
4.725e-02 | -3.05 | regulation of endocytosis | biological process | GO:0030100 | 295 | 3 | 18204 | 50 |
SYK,BMP2K,HCK |
4.752e-02 | -3.05 | Integrin_alpha_Ig-like_2 | interpro domains | IPR048285 | 18 | 1 | 18521 | 50 |
ITGAX |
4.752e-02 | -3.05 | Integrin_alpha | interpro domains | IPR000413 | 18 | 1 | 18521 | 50 |
ITGAX |
4.765e-02 | -3.04 | Formin, FH2 domain | gene3d domains | 1.20.58.2220 | 15 | 1 | 14470 | 47 |
DIAPH2 |
4.766e-02 | -3.04 | monoatomic anion:sodium symporter activity | molecular function | GO:0015373 | 18 | 1 | 18094 | 49 |
SLC13A1 |
4.774e-02 | -3.04 | MFSD4B (major facilitator superfamily domain containing 4B) | protein interactions | 91749 | 19 | 1 | 19454 | 50 |
GNAI2 |
4.774e-02 | -3.04 | CLIC2 (chloride intracellular channel 2) | protein interactions | 1193 | 19 | 1 | 19454 | 50 |
RPL35 |
4.774e-02 | -3.04 | ZNF791 (zinc finger protein 791) | protein interactions | 163049 | 19 | 1 | 19454 | 50 |
RPL13A |
4.774e-02 | -3.04 | FAM199X (family with sequence similarity 199, X-linked) | protein interactions | 139231 | 19 | 1 | 19454 | 50 |
RPL37A |
4.774e-02 | -3.04 | PEX2 (peroxisomal biogenesis factor 2) | protein interactions | 5828 | 19 | 1 | 19454 | 50 |
PTPN6 |
4.774e-02 | -3.04 | SLC26A4-AS1 (SLC26A4 antisense RNA 1) | protein interactions | 286002 | 19 | 1 | 19454 | 50 |
RPS25 |
4.774e-02 | -3.04 | NACAD (NAC alpha domain containing) | protein interactions | 23148 | 19 | 1 | 19454 | 50 |
NTRK1 |
4.774e-02 | -3.04 | SPOCK2 (SPARC (osteonectin), cwcv and kazal like domains proteoglycan 2) | protein interactions | 9806 | 19 | 1 | 19454 | 50 |
RPS14 |
4.774e-02 | -3.04 | TBX20 (T-box transcription factor 20) | protein interactions | 57057 | 19 | 1 | 19454 | 50 |
PDZRN3 |
4.774e-02 | -3.04 | ZNF273 (zinc finger protein 273) | protein interactions | 10793 | 19 | 1 | 19454 | 50 |
RPL27A |
4.774e-02 | -3.04 | Cep76 (centrosomal protein 76) | protein interactions | 225659 | 19 | 1 | 19454 | 50 |
GNAI2 |
4.774e-02 | -3.04 | RIT2 (Ras like without CAAX 2) | protein interactions | 6014 | 19 | 1 | 19454 | 50 |
RGL1 |
4.774e-02 | -3.04 | CSF1 (colony stimulating factor 1) | protein interactions | 1435 | 19 | 1 | 19454 | 50 |
CSF1R |
4.774e-02 | -3.04 | SIT1 (signaling threshold regulating transmembrane adaptor 1) | protein interactions | 27240 | 19 | 1 | 19454 | 50 |
SYK |
4.774e-02 | -3.04 | INPP4A (inositol polyphosphate-4-phosphatase type I A) | protein interactions | 3631 | 19 | 1 | 19454 | 50 |
NTRK1 |
4.775e-02 | -3.04 | endocytosis | biological process | GO:0006897 | 499 | 4 | 18204 | 50 |
SYK,FCHO2,HCK,ELMO1 |
4.779e-02 | -3.04 | CDK13 (cyclin dependent kinase 13) | protein interactions | 8621 | 136 | 2 | 19454 | 50 |
RPL13A,NTRK1 |
4.779e-02 | -3.04 | PYGB (glycogen phosphorylase B) | protein interactions | 5834 | 136 | 2 | 19454 | 50 |
FYB1,NTRK1 |
4.793e-02 | -3.04 | skin-back-malignant_melanoma | COSMIC cancer mutations | skin-back-malignant_melanoma | 280 | 3 | 16828 | 49 |
ADAM28,NTRK1,DCC |
4.798e-02 | -3.04 | cell activation | biological process | GO:0001775 | 725 | 5 | 18204 | 50 |
ENTPD1,CD74,NTRK1,SYK,PTPN6 |
4.804e-02 | -3.04 | positive regulation of cytokine production | biological process | GO:0001819 | 500 | 4 | 18204 | 50 |
CSF1R,CD74,RBM47,SYK |
4.804e-02 | -3.04 | regulation of cell-cell adhesion | biological process | GO:0022407 | 500 | 4 | 18204 | 50 |
PTPN6,SYK,CD74,SH2B3 |
4.828e-02 | -3.03 | SAR1A (secretion associated Ras related GTPase 1A) | protein interactions | 56681 | 318 | 3 | 19454 | 50 |
RPL18A,RPL35,RPL8 |
4.828e-02 | -3.03 | RHOT2 (ras homolog family member T2) | protein interactions | 89941 | 318 | 3 | 19454 | 50 |
NTRK1,CD74,RPS26 |
4.832e-02 | -3.03 | regulation of granulocyte macrophage colony-stimulating factor production | biological process | GO:0032645 | 18 | 1 | 18204 | 50 |
SYK |
4.832e-02 | -3.03 | ceramide transport | biological process | GO:0035627 | 18 | 1 | 18204 | 50 |
PSAP |
4.832e-02 | -3.03 | cell-cell junction maintenance | biological process | GO:0045217 | 18 | 1 | 18204 | 50 |
CSF1R |
4.832e-02 | -3.03 | positive regulation of myelination | biological process | GO:0031643 | 18 | 1 | 18204 | 50 |
ITGAX |
4.832e-02 | -3.03 | negative regulation of platelet activation | biological process | GO:0010544 | 18 | 1 | 18204 | 50 |
SH2B3 |
4.832e-02 | -3.03 | retinoic acid receptor signaling pathway | biological process | GO:0048384 | 18 | 1 | 18204 | 50 |
RXRA |
4.832e-02 | -3.03 | gamma-delta T cell activation | biological process | GO:0046629 | 18 | 1 | 18204 | 50 |
SYK |
4.832e-02 | -3.03 | regulation of humoral immune response mediated by circulating immunoglobulin | biological process | GO:0002923 | 18 | 1 | 18204 | 50 |
PTPN6 |
4.832e-02 | -3.03 | clathrin coat assembly | biological process | GO:0048268 | 18 | 1 | 18204 | 50 |
FCHO2 |
4.832e-02 | -3.03 | positive regulation of type 2 immune response | biological process | GO:0002830 | 18 | 1 | 18204 | 50 |
CD74 |
4.832e-02 | -3.03 | secretory granule localization | biological process | GO:0032252 | 18 | 1 | 18204 | 50 |
CADPS2 |
4.832e-02 | -3.03 | negative regulation of lyase activity | biological process | GO:0051350 | 18 | 1 | 18204 | 50 |
GNAI2 |
4.832e-02 | -3.03 | regulation of clathrin-dependent endocytosis | biological process | GO:2000369 | 18 | 1 | 18204 | 50 |
BMP2K |
4.839e-02 | -3.03 | haematopoietic_and_lymphoid_tissue-haematopoietic_neoplasm-chronic_eosinophilic_leukaemia-hypereosinophilic_syndrome | COSMIC cancer mutations | haematopoietic_and_lymphoid_tissue-haematopoietic_neoplasm-chronic_eosinophilic_leukaemia-hypereosinophilic_syndrome | 17 | 1 | 16828 | 49 |
SH2B3 |
4.839e-02 | -3.03 | chronic_eosinophilic_leukaemia-hypereosinophilic_syndrome | COSMIC cancer mutations | chronic_eosinophilic_leukaemia-hypereosinophilic_syndrome | 17 | 1 | 16828 | 49 |
SH2B3 |
4.842e-02 | -3.03 | NCOA6 (nuclear receptor coactivator 6) | protein interactions | 23054 | 137 | 2 | 19454 | 50 |
PDE6D,RXRA |
4.842e-02 | -3.03 | PUM2 (pumilio RNA binding family member 2) | protein interactions | 23369 | 137 | 2 | 19454 | 50 |
RBM47,NTRK1 |
4.842e-02 | -3.03 | SUPV3L1 (Suv3 like RNA helicase) | protein interactions | 6832 | 137 | 2 | 19454 | 50 |
NTRK1,RBM47 |
4.842e-02 | -3.03 | C3 (complement C3) | protein interactions | 718 | 137 | 2 | 19454 | 50 |
ITGAX,PDE6D |
4.842e-02 | -3.03 | DCTN4 (dynactin subunit 4) | protein interactions | 51164 | 137 | 2 | 19454 | 50 |
RPL36A,NTRK1 |
4.905e-02 | -3.01 | IL7R (interleukin 7 receptor) | protein interactions | 3575 | 138 | 2 | 19454 | 50 |
RPL8,RPS20 |
4.905e-02 | -3.01 | PTCD1 (pentatricopeptide repeat domain 1) | protein interactions | 26024 | 138 | 2 | 19454 | 50 |
CARD10,RBM47 |
4.906e-02 | -3.01 | FXR1 (FMR1 autosomal homolog 1) | protein interactions | 8087 | 538 | 4 | 19454 | 50 |
NTRK1,RPS20,HCK,SPECC1 |
4.906e-02 | -3.01 | DYRK1A (dual specificity tyrosine phosphorylation regulated kinase 1A) | protein interactions | 1859 | 538 | 4 | 19454 | 50 |
HIPK2,NTRK1,PSAP,RPS26 |
4.933e-02 | -3.01 | haematopoietic_and_lymphoid_tissue-lymph_node-lymphoid_neoplasm-mantle_cell_lymphoma | COSMIC cancer mutations | haematopoietic_and_lymphoid_tissue-lymph_node-lymphoid_neoplasm-mantle_cell_lymphoma | 476 | 4 | 16828 | 49 |
PDZRN3,SLC13A1,DCC,HIPK2 |
4.940e-02 | -3.01 | TXN (thioredoxin) | protein interactions | 7295 | 321 | 3 | 19454 | 50 |
PTPN6,PSAP,NTRK1 |
4.941e-02 | -3.01 | RASGEF | prosite domains | PS00720 | 14 | 1 | 12186 | 44 |
RGL1 |
4.941e-02 | -3.01 | MHD | prosite domains | PS51072 | 14 | 1 | 12186 | 44 |
FCHO2 |
4.941e-02 | -3.01 | Integrin_A_Ig_2 | pfam domains | PF20805 | 18 | 1 | 17795 | 50 |
ITGAX |
4.941e-02 | -3.01 | ADAM_CR | pfam domains | PF08516 | 18 | 1 | 17795 | 50 |
ADAM28 |
4.962e-02 | -3.00 | negative regulation of T cell activation | biological process | GO:0050868 | 130 | 2 | 18204 | 50 |
PTPN6,CD74 |
4.962e-02 | -3.00 | B cell differentiation | biological process | GO:0030183 | 130 | 2 | 18204 | 50 |
NTRK1,SYK |
4.968e-02 | -3.00 | NUP188 (nucleoporin 188) | protein interactions | 23511 | 139 | 2 | 19454 | 50 |
CTSS,NTRK1 |
4.968e-02 | -3.00 | NAA15 (N-alpha-acetyltransferase 15, NatA auxiliary subunit) | protein interactions | 80155 | 139 | 2 | 19454 | 50 |
RPS20,NTRK1 |
4.977e-02 | -3.00 | orf1ab (1A polyprotein;1AB polyprotein) | protein interactions | 14254602 | 322 | 3 | 19454 | 50 |
RPS25,IVNS1ABP,RPL37A |
4.978e-02 | -3.00 | FH2 | smart domains | SM00498 | 15 | 1 | 9717 | 33 |
DIAPH2 |