Gene Ontology Enrichment Results

Homer de novo Motif Enrichment Results
Known Motif Enrichment Results

Text file version of complete results (i.e. open with Excel)

biological process: Functional groupings of proteins (Gene Ontology)

molecular function: Mechanistic actions of proteins (Gene Ontology)

cellular component: Protein localization (Gene Ontology)

chromosome location: Genes with similar chromosome localization (NCBI Gene)

KEGG pathways: Groups of proteins in the same pathways (KEGG)

protein interactions: "Proteins interacting with a common protein (BIND, EcoCyc, HPRD)" (NCBI Gene)

interpro domains: Proteins with similar domains and features (Interpro)

pfam domains: Proteins with similar domains and features (Pfam)

smart domains: Proteins with similar domains and features (SMART)

gene3d domains: Proteins with similar domains and features (Gene3D)

prosite domains: Proteins with similar domains and features (Prosite)

prints domains: Proteins with similar domains and features (PRINTS)

MSigDB lists: "Genes sets for pathways, factor/miRNA target predictions, expression patterns, etc." (MSigDB)

BIOCYC pathways: Groups of proteins in the same pathways (BIOCYC)

COSMIC cancer mutations: Genes mutated in similar cancers (COSMIC)

GWAS genes: Genes mutated in similar diseases (GWAS Catalog)

Lipid Maps pathways: Groups of proteins in the same lipid pathways (Lipid Maps/Biosystems)

Pathway Interaction DB: Groups of proteins in the same pathways (Pathway Interaction Database)

REACTOME pathways: Groups of proteins in the same pathways (REACTOME)

SMPDB pathways: Groups of proteins in the same pathways (SMPDB)

WikiPathways: Groups of proteins in the same pathways (Wikipathways)

Enriched Categories

P-value	ln(P)	Term	GO Tree	GO ID	# of Genes in Term	# of Target Genes in Term	# of Total Genes	# of Target Genes	Common Genes
7.393e-11	-23.33	central_nervous_system-brain-primitive_neuroectodermal_tumour-medulloblastoma	COSMIC cancer mutations	central_nervous_system-brain-primitive_neuroectodermal_tumour-medulloblastoma	7205	43	16828	49	SLC1A3,TNS3,SLC1A2,NHSL1,FARP1,CTNND2,SNTB1,EGF,GRK5,COL11A1,ITPK1,SORCS2,USP6NL,ITPR2,GPC5,NFIA,GPM6B,PRDM16,GRIP1,RORA,ELOVL2,LRIG1,SLC6A11,ADAM12,PREX1,FHOD3,PTN,DGKB,NCKAP5,QKI,PREX2,SLC4A4,NTRK2,ZBTB20,SOX5,TRPS1,RFX4,SLC13A5,FKBP5,NPAS3,LPIN2,PTPRZ1,SLC39A12
2.612e-09	-19.76	haematopoietic_and_lymphoid_tissue-haematopoietic_neoplasm-acute_myeloid_leukaemia_therapy_related	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue-haematopoietic_neoplasm-acute_myeloid_leukaemia_therapy_related	1523	20	16828	49	NTRK2,ITPR2,GPC5,GRK5,PREX2,ITPK1,SORCS2,NCKAP5,DGKB,QKI,TNS3,SLC1A3,CTNND2,FARP1,PREX1,FHOD3,SLC6A11,PRDM16,RORA,SOX5
2.612e-09	-19.76	acute_myeloid_leukaemia_therapy_related	COSMIC cancer mutations	acute_myeloid_leukaemia_therapy_related	1523	20	16828	49	SOX5,PRDM16,RORA,SLC6A11,PREX1,FHOD3,TNS3,SLC1A3,CTNND2,FARP1,NCKAP5,DGKB,QKI,PREX2,GRK5,SORCS2,ITPK1,NTRK2,ITPR2,GPC5
3.883e-09	-19.37	Burkitt_lymphoma	COSMIC cancer mutations	Burkitt_lymphoma	2119	23	16828	49	PREX2,NTRK2,DGKB,NCKAP5,RFX4,SOX5,NPAS3,SORCS2,ITPK1,COL11A1,GRK5,GPC5,ITPR2,CTNND2,SLC1A2,NHSL1,SLC1A3,EGF,SNTB1,LRIG1,FHOD3,GRIP1,PRDM16
3.883e-09	-19.37	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-Burkitt_lymphoma	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-Burkitt_lymphoma	2119	23	16828	49	PREX2,NTRK2,DGKB,NCKAP5,SOX5,RFX4,NPAS3,GRK5,ITPK1,SORCS2,COL11A1,ITPR2,GPC5,SLC1A3,CTNND2,SLC1A2,NHSL1,SNTB1,EGF,LRIG1,FHOD3,PRDM16,GRIP1
4.955e-09	-19.12	intestinal_adenocarcinoma	COSMIC cancer mutations	intestinal_adenocarcinoma	7225	41	16828	49	NPAS3,RFX4,SOX5,TRPS1,SLC39A12,PTPRZ1,QKI,DGKB,NCKAP5,NRCAM,PTN,ZBTB20,NTRK2,SLC4A4,PREX2,RORA,GRIP1,PRDM16,NFIA,AQP4,CTBP1,FHOD3,FGFRL1,PREX1,ADAM12,SLC6A11,LRIG1,APOA1,EGF,SNTB1,CTNND2,SLC1A2,NHSL1,FARP1,TNS3,ITPR2,SORCS2,USP6NL,ITPK1,COL11A1,GRK5
4.955e-09	-19.12	stomach-carcinoma-intestinal_adenocarcinoma	COSMIC cancer mutations	stomach-carcinoma-intestinal_adenocarcinoma	7225	41	16828	49	ITPK1,USP6NL,SORCS2,COL11A1,GRK5,ITPR2,CTNND2,FARP1,SLC1A2,NHSL1,TNS3,APOA1,EGF,SNTB1,ADAM12,SLC6A11,LRIG1,CTBP1,FGFRL1,FHOD3,PREX1,AQP4,NFIA,RORA,PRDM16,GRIP1,SLC4A4,PREX2,ZBTB20,NTRK2,PTN,NRCAM,QKI,DGKB,NCKAP5,SLC39A12,PTPRZ1,RFX4,SOX5,TRPS1,NPAS3
9.497e-09	-18.47	brainstem	COSMIC cancer mutations	brainstem	3102	27	16828	49	ELOVL2,FHOD3,PREX1,RORA,GRIP1,PRDM16,COL11A1,ITPK1,USP6NL,GRK5,GPC5,ITPR2,SLC1A2,CTNND2,SLC1A3,TNS3,EGF,SNTB1,PTPRZ1,SLC39A12,SOX5,NPAS3,PREX2,ZBTB20,PTN,QKI,NCKAP5
2.195e-08	-17.63	central_nervous_system-brainstem-glioma-astrocytoma_Grade_IV	COSMIC cancer mutations	central_nervous_system-brainstem-glioma-astrocytoma_Grade_IV	2531	24	16828	49	SOX5,PTPRZ1,SLC39A12,PTN,NCKAP5,QKI,PREX2,ZBTB20,PRDM16,GRIP1,RORA,ELOVL2,PREX1,FHOD3,SLC1A3,TNS3,CTNND2,SNTB1,GRK5,COL11A1,USP6NL,ITPK1,ITPR2,GPC5
8.769e-08	-16.25	nervous system development	biological process	GO:0007399	2185	21	18204	50	RFX4,ITPK1,GPM6B,PTN,NFIA,MSI2,SLC39A12,SLC1A3,NTRK2,NRCAM,QKI,RORA,PTPRZ1,SOX5,PREX2,CTNND2,SLC1A2,ADGRB3,LRIG1,FARP1,EGF
2.059e-07	-15.40	acute_lymphoblastic_B_cell_leukaemia	COSMIC cancer mutations	acute_lymphoblastic_B_cell_leukaemia	3828	28	16828	49	NFIA,RORA,GRIP1,PRDM16,SLC6A11,FHOD3,CTNND2,SLC1A2,TNS3,SLC1A3,EGF,SNTB1,USP6NL,ITPK1,SORCS2,COL11A1,GRK5,GPC5,ITPR2,SOX5,LPIN2,PTPRZ1,NRCAM,NCKAP5,SLC4A4,PREX2,ZBTB20,NTRK2
2.059e-07	-15.40	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-acute_lymphoblastic_B_cell_leukaemia	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-acute_lymphoblastic_B_cell_leukaemia	3828	28	16828	49	COL11A1,SORCS2,USP6NL,ITPK1,GRK5,GPC5,ITPR2,SLC1A2,CTNND2,SLC1A3,TNS3,EGF,SNTB1,SLC6A11,FHOD3,NFIA,RORA,GRIP1,PRDM16,SLC4A4,PREX2,NTRK2,ZBTB20,NRCAM,NCKAP5,LPIN2,PTPRZ1,SOX5
2.356e-07	-15.26	angiosarcoma	COSMIC cancer mutations	angiosarcoma	2192	21	16828	49	TNS3,PTN,SLC1A3,CTNND2,SLC1A2,FARP1,DGKB,NCKAP5,SNTB1,PREX2,SORCS2,COL11A1,NTRK2,ITPR2,GPC5,SOX5,PRDM16,GRIP1,SLC39A12,PTPRZ1,FHOD3
2.356e-07	-15.26	soft_tissue-blood_vessel-angiosarcoma	COSMIC cancer mutations	soft_tissue-blood_vessel-angiosarcoma	2192	21	16828	49	SNTB1,NCKAP5,DGKB,CTNND2,SLC1A2,FARP1,TNS3,PTN,SLC1A3,GPC5,ITPR2,NTRK2,SORCS2,COL11A1,PREX2,GRIP1,PRDM16,SOX5,FHOD3,SLC39A12,PTPRZ1
2.546e-07	-15.18	system development	biological process	GO:0048731	3533	26	18204	50	APOA1,EGF,FARP1,LRIG1,FGFRL1,SOX5,PTPRZ1,RORA,NTRK2,NRCAM,COL11A1,NFIA,ITPK1,FHOD3,ADGRB3,SLC1A2,CTNND2,PREX2,QKI,SLC39A12,SLC1A3,MSI2,PTN,GPM6B,TRPS1,RFX4
2.687e-07	-15.13	cell periphery	cellular component	GO:0071944	6020	33	19108	49	GRIP1,ADAM12,EGF,PREX2,NRCAM,ADGRB3,GPC5,FARP1,SLC1A2,SLC1A3,ITPR2,SLC39A12,PTPRZ1,DGKB,CTBP1,PTN,SLC13A5,SNTB1,SORCS2,NTRK2,CTNND2,SLC6A11,USP6NL,GPM6B,ITPK1,SLC4A4,AQP4,LRIG1,APOA1,COL11A1,PREX1,FGFRL1,GRK5
2.732e-07	-15.11	blood_vessel	COSMIC cancer mutations	blood_vessel	2211	21	16828	49	GPC5,ITPR2,NTRK2,SORCS2,COL11A1,PREX2,SNTB1,DGKB,NCKAP5,CTNND2,FARP1,SLC1A2,TNS3,PTN,SLC1A3,FHOD3,SLC39A12,PTPRZ1,PRDM16,GRIP1,SOX5
4.168e-07	-14.69	synapse	cellular component	GO:0045202	1473	16	19108	49	FARP1,SLC1A2,SLC1A3,DGKB,PTPRZ1,PTN,QKI,CTBP1,SORCS2,SNTB1,NTRK2,GRIP1,CTNND2,NRCAM,SLC6A11,ADGRB3
6.193e-07	-14.29	anatomical structure morphogenesis	biological process	GO:0009653	2225	20	18204	50	SLC39A12,SLC1A3,NTRK2,NRCAM,COL11A1,ADAM12,NFIA,PTN,EGF,FHOD3,FARP1,CTNND2,LRIG1,ADGRB3,PTPRZ1,QKI,RORA,PREX2,SOX5,FGFRL1
6.317e-07	-14.27	solute:monoatomic cation symporter activity	molecular function	GO:0015294	117	6	18094	48	SLC1A3,SLC39A12,SLC4A4,SLC13A5,SLC6A11,SLC1A2
6.436e-07	-14.26	plasma membrane	cellular component	GO:0005886	5538	31	19108	49	SORCS2,SLC13A5,SNTB1,NTRK2,CTNND2,USP6NL,SLC6A11,SLC4A4,ITPK1,GPM6B,AQP4,LRIG1,APOA1,FGFRL1,PREX1,GRK5,GRIP1,ADAM12,PREX2,EGF,ADGRB3,NRCAM,GPC5,SLC1A2,FARP1,ITPR2,SLC1A3,SLC39A12,PTPRZ1,DGKB,PTN
9.787e-07	-13.84	cell junction	cellular component	GO:0030054	2224	19	19108	49	GRIP1,NTRK2,SORCS2,SNTB1,NFIA,SLC6A11,ADGRB3,NRCAM,CTNND2,SLC1A3,TNS3,SLC1A2,FARP1,CTBP1,QKI,PTN,FGFRL1,PTPRZ1,DGKB
1.475e-06	-13.43	cerebellum	COSMIC cancer mutations	cerebellum	769	12	16828	49	GRIP1,PRDM16,NPAS3,PTPRZ1,FHOD3,QKI,NRCAM,CTNND2,ITPR2,NTRK2,GPC5,SORCS2
1.699e-06	-13.29	neurogenesis	biological process	GO:0022008	1334	15	18204	50	NRCAM,NTRK2,SLC39A12,SLC1A3,NFIA,PTN,GPM6B,FARP1,SOX5,PREX2,RORA,QKI,PTPRZ1,ADGRB3,CTNND2
1.771e-06	-13.24	generation of neurons	biological process	GO:0048699	1158	14	18204	50	PTN,NFIA,GPM6B,NRCAM,NTRK2,SLC1A3,SLC39A12,SOX5,PREX2,RORA,PTPRZ1,ADGRB3,CTNND2,FARP1
1.845e-06	-13.20	prostate-carcinoma	COSMIC cancer mutations	prostate-carcinoma	9000	42	16828	49	ADAM12,LRIG1,ELOVL2,FHOD3,FGFRL1,PREX1,NFIA,RORA,PRDM16,GRIP1,COL11A1,SORCS2,ITPK1,GRK5,GPC5,ITPR2,SLC1A2,FARP1,NHSL1,CTNND2,SLC1A3,TNS3,EGF,APOA1,SNTB1,LPIN2,PTPRZ1,SLC39A12,RFX4,TRPS1,SOX5,SLC13A5,NPAS3,SLC4A4,PREX2,MSI2,NTRK2,ZBTB20,NRCAM,QKI,NCKAP5,DGKB
2.083e-06	-13.08	developmental process	biological process	GO:0032502	5716	32	18204	50	MSI2,GPM6B,PTN,RFX4,TRPS1,SLC1A3,SLC39A12,PRDM16,NHSL1,CTBP1,ADGRB3,CTNND2,SLC1A2,PREX2,QKI,FHOD3,PREX1,ADAM12,GRK5,ITPK1,NFIA,NRCAM,NTRK2,COL11A1,LRIG1,SOX5,FGFRL1,RORA,PTPRZ1,EGF,APOA1,FARP1
2.148e-06	-13.05	organic acid:sodium symporter activity	molecular function	GO:0005343	35	4	18094	48	SLC13A5,SLC1A2,SLC6A11,SLC1A3
2.196e-06	-13.03	solute:sodium symporter activity	molecular function	GO:0015370	80	5	18094	48	SLC6A11,SLC1A3,SLC4A4,SLC1A2,SLC13A5
2.259e-06	-13.00	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-mantle_cell_lymphoma	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-mantle_cell_lymphoma	2737	22	16828	49	DGKB,NCKAP5,NTRK2,PREX2,SLC13A5,SOX5,TRPS1,RFX4,SLC1A3,FARP1,SLC1A2,CTNND2,ITPR2,GPC5,COL11A1,SORCS2,ITPK1,GRIP1,PRDM16,PREX1,ELOVL2,LRIG1
2.501e-06	-12.90	symporter activity	molecular function	GO:0015293	148	6	18094	48	SLC1A3,SLC39A12,SLC4A4,SLC13A5,SLC6A11,SLC1A2
2.521e-06	-12.89	multicellular organism development	biological process	GO:0007275	3957	26	18204	50	QKI,PREX2,CTNND2,SLC1A2,ADGRB3,FHOD3,RFX4,TRPS1,GPM6B,PTN,MSI2,SLC39A12,SLC1A3,RORA,PTPRZ1,SOX5,FGFRL1,LRIG1,FARP1,EGF,APOA1,ITPK1,NFIA,COL11A1,NRCAM,NTRK2
3.019e-06	-12.71	soft_tissue	COSMIC cancer mutations	soft_tissue	5828	33	16828	49	SOX5,TRPS1,NPAS3,SLC39A12,PTPRZ1,PTN,DGKB,NCKAP5,PREX2,NTRK2,NFIA,AQP4,RORA,PRDM16,GRIP1,ELOVL2,CTBP1,FGFRL1,FHOD3,CTNND2,SLC1A2,NHSL1,FARP1,TNS3,SLC1A3,EGF,SNTB1,SORCS2,USP6NL,COL11A1,GRK5,GPC5,ITPR2
4.477e-06	-12.32	mantle_cell_lymphoma	COSMIC cancer mutations	mantle_cell_lymphoma	2849	22	16828	49	DGKB,NCKAP5,NTRK2,PREX2,SLC13A5,TRPS1,SOX5,RFX4,SLC1A3,SLC1A2,FARP1,CTNND2,ITPR2,GPC5,COL11A1,ITPK1,SORCS2,PRDM16,GRIP1,PREX1,LRIG1,ELOVL2
4.805e-06	-12.25	neuron differentiation	biological process	GO:0030182	1081	13	18204	50	ADGRB3,CTNND2,PREX2,PTPRZ1,RORA,FARP1,PTN,NFIA,GPM6B,NTRK2,NRCAM,SLC1A3,SLC39A12
4.959e-06	-12.21	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm	7307	37	16828	49	NTRK2,PREX2,QKI,NCKAP5,DGKB,PTN,PTPRZ1,LPIN2,SLC13A5,FKBP5,RFX4,SOX5,GPC5,ITPR2,COL11A1,ITPK1,USP6NL,SORCS2,GRK5,EGF,SNTB1,FARP1,NHSL1,SLC1A2,CTNND2,SLC1A3,TNS3,FGFRL1,FHOD3,CTBP1,PREX1,LRIG1,ELOVL2,SLC6A11,RORA,PRDM16,GRIP1
6.705e-06	-11.91	carcinoid-endocrine_tumour	COSMIC cancer mutations	carcinoid-endocrine_tumour	7752	38	16828	49	CTNND2,SLC1A2,NHSL1,FARP1,TNS3,SLC1A3,EGF,SNTB1,USP6NL,ITPK1,COL11A1,GRK5,GPC5,ITPR2,RORA,PRDM16,GRIP1,SLC6A11,LRIG1,ELOVL2,CTBP1,FGFRL1,FHOD3,PREX1,NRCAM,PTN,QKI,NCKAP5,DGKB,SLC4A4,PREX2,NTRK2,RFX4,TRPS1,SOX5,SLC13A5,FKBP5,PTPRZ1
6.831e-06	-11.89	postsynaptic membrane	cellular component	GO:0045211	280	7	19108	49	ADGRB3,SLC6A11,NRCAM,DGKB,GRIP1,SORCS2,FARP1
7.318e-06	-11.83	synaptic membrane	cellular component	GO:0097060	400	8	19108	49	DGKB,NRCAM,SLC6A11,ADGRB3,FARP1,SLC1A2,SORCS2,GRIP1
7.407e-06	-11.81	bone	COSMIC cancer mutations	bone	8157	39	16828	49	RORA,PRDM16,GRIP1,GPM6B,FGFRL1,FHOD3,PREX1,ADAM12,ELOVL2,LRIG1,SLC6A11,EGF,SNTB1,FARP1,CTNND2,SLC1A3,TNS3,GPC5,ITPR2,COL11A1,ITPK1,USP6NL,SORCS2,GRK5,SLC13A5,NPAS3,TRPS1,SOX5,PTPRZ1,SLC39A12,LPIN2,QKI,DGKB,NCKAP5,NRCAM,NTRK2,ZBTB20,SLC4A4,PREX2
8.071e-06	-11.73	Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour	COSMIC cancer mutations	Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour	7434	37	16828	49	PREX1,FGFRL1,FHOD3,LRIG1,ELOVL2,SLC6A11,ADAM12,GRIP1,PRDM16,RORA,GPM6B,ITPR2,GRK5,COL11A1,ITPK1,USP6NL,SORCS2,SNTB1,EGF,SLC1A3,TNS3,FARP1,CTNND2,PTPRZ1,SLC39A12,LPIN2,SLC13A5,NPAS3,TRPS1,SOX5,NTRK2,ZBTB20,PREX2,SLC4A4,NCKAP5,QKI,NRCAM
8.161e-06	-11.72	cell differentiation	biological process	GO:0030154	3645	24	18204	50	QKI,PREX2,CTNND2,ADGRB3,FHOD3,GPM6B,PTN,MSI2,CTBP1,NHSL1,PRDM16,SLC39A12,SLC1A3,PTPRZ1,RORA,SOX5,FARP1,NFIA,GRK5,PREX1,ADAM12,COL11A1,NRCAM,NTRK2
8.282e-06	-11.70	cellular developmental process	biological process	GO:0048869	3648	24	18204	50	MSI2,GPM6B,PTN,SLC39A12,SLC1A3,CTBP1,NHSL1,PRDM16,CTNND2,ADGRB3,QKI,PREX2,FHOD3,GRK5,PREX1,ADAM12,NFIA,NTRK2,NRCAM,COL11A1,PTPRZ1,RORA,SOX5,FARP1
9.417e-06	-11.57	haematopoietic_and_lymphoid_tissue-haematopoietic_neoplasm	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue-haematopoietic_neoplasm	764	11	16828	49	FHOD3,SLC6A11,SOX5,NTRK2,GPC5,PREX2,GRK5,SORCS2,NCKAP5,DGKB,SLC1A2
1.549e-05	-11.08	pancreas-carcinoid-endocrine_tumour	COSMIC cancer mutations	pancreas-carcinoid-endocrine_tumour	7250	36	16828	49	FGFRL1,FHOD3,CTBP1,PREX1,LRIG1,ELOVL2,SLC6A11,RORA,GRIP1,PRDM16,GPC5,ITPR2,COL11A1,USP6NL,ITPK1,GRK5,EGF,SNTB1,SLC1A2,NHSL1,FARP1,CTNND2,SLC1A3,TNS3,SLC13A5,FKBP5,RFX4,SOX5,NTRK2,SLC4A4,PREX2,QKI,DGKB,NCKAP5,PTN,NRCAM
1.611e-05	-11.04	face	COSMIC cancer mutations	face	2139	18	16828	49	PTPRZ1,FHOD3,SLC6A11,ADAM12,GRIP1,PRDM16,SLC13A5,RORA,TRPS1,AQP4,ITPR2,GPC5,GRK5,PREX2,MSI2,COL11A1,EGF,FARP1
1.668e-05	-11.00	neuron development	biological process	GO:0048666	859	11	18204	50	SLC1A3,SLC39A12,NTRK2,NRCAM,GPM6B,PTN,FARP1,CTNND2,ADGRB3,PTPRZ1,PREX2
1.804e-05	-10.92	diffuse_large_B_cell_lymphoma	COSMIC cancer mutations	diffuse_large_B_cell_lymphoma	4151	26	16828	49	QKI,NCKAP5,DGKB,PREX2,NTRK2,TRPS1,SOX5,FARP1,SLC1A2,CTNND2,SLC1A3,TNS3,EGF,SNTB1,COL11A1,SORCS2,USP6NL,GRK5,GPC5,ITPR2,AQP4,RORA,GRIP1,PRDM16,SLC6A11,FHOD3
2.020e-05	-10.81	chondroblastoma	COSMIC cancer mutations	chondroblastoma	534	9	16828	49	PREX1,GPC5,FHOD3,SNTB1,NCKAP5,EGF,SOX5,CTNND2,FARP1
2.137e-05	-10.75	myelodysplastic_syndrome	COSMIC cancer mutations	myelodysplastic_syndrome	1174	13	16828	49	NTRK2,SORCS2,PREX2,GRK5,EGF,NCKAP5,DGKB,SLC1A2,FHOD3,SLC6A11,NPAS3,NFIA,SOX5
2.137e-05	-10.75	haematopoietic_and_lymphoid_tissue-haematopoietic_neoplasm-myelodysplastic_syndrome	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue-haematopoietic_neoplasm-myelodysplastic_syndrome	1174	13	16828	49	SLC1A2,NFIA,SOX5,EGF,NPAS3,NCKAP5,DGKB,SORCS2,GRK5,PREX2,SLC6A11,FHOD3,NTRK2
2.787e-05	-10.49	kidney-other-neoplasm	COSMIC cancer mutations	kidney-other-neoplasm	10653	44	16828	49	USP6NL,SORCS2,GPC5,NHSL1,FARP1,SLC1A2,CTNND2,SLC1A3,APOA1,ELOVL2,LRIG1,SLC6A11,FHOD3,CTBP1,AQP4,RORA,GRIP1,PREX2,ZBTB20,NRCAM,PTN,QKI,DGKB,NCKAP5,LPIN2,PTPRZ1,RFX4,TRPS1,FKBP5,COL11A1,ITPK1,GRK5,ITPR2,TNS3,EGF,SNTB1,FGFRL1,PREX1,PRDM16,NTRK2,SLC39A12,SOX5,SLC13A5,NPAS3
2.834e-05	-10.47	dendrite morphogenesis	biological process	GO:0048813	64	4	18204	50	CTNND2,PTN,FARP1,PREX2
2.893e-05	-10.45	pharynx	COSMIC cancer mutations	pharynx	2696	20	16828	49	QKI,EGF,NCKAP5,CTNND2,NHSL1,SLC1A2,NRCAM,GPC5,NTRK2,SORCS2,COL11A1,SLC4A4,PREX2,NPAS3,RFX4,NFIA,FGFRL1,SLC39A12,PTPRZ1,ADAM12
2.973e-05	-10.42	lymphoid_neoplasm	COSMIC cancer mutations	lymphoid_neoplasm	12233	47	16828	49	NTRK2,SLC4A4,SLC39A12,NPAS3,SLC13A5,SOX5,ITPR2,GRK5,ITPK1,COL11A1,SNTB1,EGF,TNS3,PREX1,FGFRL1,PRDM16,NFIA,ZBTB20,MSI2,PREX2,DGKB,NCKAP5,QKI,PTN,NRCAM,PTPRZ1,LPIN2,FKBP5,TRPS1,RFX4,GPC5,SORCS2,USP6NL,SLC1A3,CTNND2,FARP1,SLC1A2,NHSL1,CTBP1,FHOD3,SLC6A11,LRIG1,ELOVL2,ADAM12,GRIP1,RORA,AQP4
2.989e-05	-10.42	amino acid:sodium symporter activity	molecular function	GO:0005283	23	3	18094	48	SLC6A11,SLC1A3,SLC1A2
3.002e-05	-10.41	functioning	COSMIC cancer mutations	functioning	1803	16	16828	49	TNS3,NRCAM,FARP1,SLC1A2,NHSL1,NCKAP5,GRK5,COL11A1,ZBTB20,NTRK2,SOX5,RFX4,GRIP1,SLC6A11,LPIN2,PTPRZ1
3.002e-05	-10.41	adrenal_gland-adrenal_gland-adrenal_cortical_carcinoma-functioning	COSMIC cancer mutations	adrenal_gland-adrenal_gland-adrenal_cortical_carcinoma-functioning	1803	16	16828	49	LPIN2,SLC6A11,PTPRZ1,RFX4,SOX5,GRIP1,COL11A1,GRK5,NTRK2,ZBTB20,FARP1,NHSL1,SLC1A2,NRCAM,TNS3,NCKAP5
3.062e-05	-10.39	oesophagus-carcinoma	COSMIC cancer mutations	oesophagus-carcinoma	4269	26	16828	49	ITPR2,COL11A1,SORCS2,USP6NL,NHSL1,CTNND2,PREX1,FHOD3,ELOVL2,LRIG1,ADAM12,PRDM16,NFIA,NTRK2,ZBTB20,PREX2,SLC4A4,NCKAP5,PTN,NRCAM,PTPRZ1,SLC39A12,SLC13A5,SOX5,TRPS1,RFX4
3.254e-05	-10.33	autonomic_ganglia	COSMIC cancer mutations	autonomic_ganglia	4005	25	16828	49	FHOD3,PREX1,NFIA,AQP4,GPM6B,PRDM16,COL11A1,USP6NL,SORCS2,SLC1A2,NHSL1,CTNND2,TNS3,EGF,SNTB1,LPIN2,PTPRZ1,RFX4,TRPS1,SLC13A5,NPAS3,SLC4A4,PREX2,NTRK2,NCKAP5
3.341e-05	-10.31	postsynapse	cellular component	GO:0098794	646	9	19108	49	NTRK2,GRIP1,SORCS2,FARP1,SLC6A11,ADGRB3,NRCAM,DGKB,CTNND2
3.352e-05	-10.30	adrenal_cortical_carcinoma	COSMIC cancer mutations	adrenal_cortical_carcinoma	2256	18	16828	49	LRIG1,LPIN2,SLC6A11,PTPRZ1,SOX5,RFX4,GRIP1,GRK5,COL11A1,NTRK2,ZBTB20,NRCAM,TNS3,NHSL1,FARP1,SLC1A2,CTNND2,NCKAP5
3.717e-05	-10.20	GOT1L1 (glutamic-oxaloacetic transaminase 1 like 1)	protein interactions	137362	4	2	19454	49	GRK5,APOA1
3.717e-05	-10.20	Ctbp2 (C-terminal binding protein 2)	protein interactions	13017	4	2	19454	49	PRDM16,TRPS1
4.065e-05	-10.11	SOX6 (SRY-box transcription factor 6)	protein interactions	55553	153	5	19454	49	NFIA,CTBP1,PRDM16,TRPS1,SOX5
4.464e-05	-10.02	anatomical structure development	biological process	GO:0048856	5207	28	18204	50	NTRK2,NRCAM,COL11A1,ADAM12,PREX1,NFIA,ITPK1,APOA1,EGF,FARP1,LRIG1,RORA,PTPRZ1,FGFRL1,SOX5,SLC39A12,SLC1A3,MSI2,TRPS1,RFX4,PTN,GPM6B,FHOD3,SLC1A2,CTNND2,ADGRB3,QKI,PREX2
4.501e-05	-10.01	multicellular organismal process	biological process	GO:0032501	6177	31	18204	50	ADGRB3,SLC1A2,CTNND2,PREX2,QKI,FHOD3,SNTB1,MSI2,PTN,GPM6B,TRPS1,RFX4,DGKB,SLC39A12,SLC1A3,LRIG1,AQP4,SOX5,FGFRL1,PTPRZ1,RORA,SLC4A4,EGF,APOA1,FARP1,PREX1,NFIA,ITPK1,NRCAM,NTRK2,COL11A1
4.848e-05	-9.93	C4-dicarboxylate transport	biological process	GO:0015740	26	3	18204	50	SLC1A2,SLC13A5,SLC1A3
4.917e-05	-9.92	Astrocytic Glutamate-Glutamine Uptake And Metabolism	REACTOME pathways	R-HSA-210455	4	2	10285	30	SLC1A3,SLC1A2
4.917e-05	-9.92	Neurotransmitter uptake and Metabolism In Glial Cells	REACTOME pathways	R-HSA-112313	4	2	10285	30	SLC1A2,SLC1A3
5.377e-05	-9.83	GSC (goosecoid homeobox)	protein interactions	145258	82	4	19454	49	TRPS1,SOX5,PRDM16,NFIA
5.570e-05	-9.80	cell development	biological process	GO:0048468	2236	17	18204	50	RORA,PTPRZ1,QKI,PREX2,CTNND2,ADGRB3,FARP1,FHOD3,GPM6B,PTN,MSI2,PREX1,COL11A1,SLC1A3,SLC39A12,NRCAM,NTRK2
6.026e-05	-9.72	sodium ion transmembrane transporter activity	molecular function	GO:0015081	158	5	18094	48	SLC6A11,SLC1A3,SLC13A5,SLC1A2,SLC4A4
6.085e-05	-9.71	positive regulation of oligodendrocyte differentiation	biological process	GO:0048714	28	3	18204	50	QKI,PTPRZ1,PTN
6.099e-05	-9.70	amino acid:monoatomic cation symporter activity	molecular function	GO:0005416	29	3	18094	48	SLC1A2,SLC6A11,SLC1A3
6.184e-05	-9.69	dicarboxylic acid transport	biological process	GO:0006835	78	4	18204	50	NTRK2,SLC1A3,SLC1A2,SLC13A5
6.236e-05	-9.68	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-diffuse_large_B_cell_lymphoma	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-diffuse_large_B_cell_lymphoma	3608	23	16828	49	SOX5,QKI,DGKB,NCKAP5,PREX2,RORA,GRIP1,PRDM16,AQP4,FHOD3,SLC6A11,EGF,SNTB1,CTNND2,FARP1,SLC1A2,TNS3,GPC5,ITPR2,SORCS2,USP6NL,COL11A1,GRK5
6.504e-05	-9.64	upper_aerodigestive_tract-mouth-carcinoma-squamous_cell_carcinoma	COSMIC cancer mutations	upper_aerodigestive_tract-mouth-carcinoma-squamous_cell_carcinoma	6953	34	16828	49	RORA,PRDM16,FHOD3,PREX1,ADAM12,ELOVL2,LRIG1,APOA1,SNTB1,NHSL1,SLC1A2,CTNND2,TNS3,GPC5,ITPR2,COL11A1,ITPK1,SORCS2,USP6NL,GRK5,SLC13A5,RFX4,SOX5,TRPS1,PTPRZ1,SLC39A12,QKI,DGKB,NCKAP5,PTN,NRCAM,ZBTB20,SLC4A4,PREX2
6.856e-05	-9.59	glutamate:sodium symporter activity	molecular function	GO:0015501	5	2	18094	48	SLC1A2,SLC1A3
6.856e-05	-9.59	high-affinity L-glutamate transmembrane transporter activity	molecular function	GO:0005314	5	2	18094	48	SLC1A2,SLC1A3
6.922e-05	-9.58	plasma membrane region	cellular component	GO:0098590	1278	12	19108	49	DGKB,SLC4A4,ITPK1,FARP1,AQP4,SLC1A2,SLC1A3,NRCAM,ADGRB3,SLC6A11,SORCS2,GRIP1
7.115e-05	-9.55	mixed_intestinal_and_diffuse_adenocarcinoma-unclassifiable	COSMIC cancer mutations	mixed_intestinal_and_diffuse_adenocarcinoma-unclassifiable	951	11	16828	49	NCKAP5,SNTB1,GRIP1,PRDM16,EGF,PTN,SLC1A2,PREX1,ITPR2,GPC5,PREX2
7.115e-05	-9.55	stomach-carcinoma-mixed_intestinal_and_diffuse_adenocarcinoma-unclassifiable	COSMIC cancer mutations	stomach-carcinoma-mixed_intestinal_and_diffuse_adenocarcinoma-unclassifiable	951	11	16828	49	PREX1,GRIP1,PRDM16,PREX2,GPC5,ITPR2,SLC1A2,PTN,EGF,SNTB1,NCKAP5
7.270e-05	-9.53	organic anion transmembrane transporter activity	molecular function	GO:0008514	268	6	18094	48	SLC6A11,SLC1A2,SLC39A12,SLC1A3,SLC13A5,SLC4A4
7.355e-05	-9.52	D-aspartate transmembrane transport	biological process	GO:0070777	5	2	18204	50	SLC1A3,SLC1A2
7.355e-05	-9.52	D-aspartate import across plasma membrane	biological process	GO:0070779	5	2	18204	50	SLC1A2,SLC1A3
7.513e-05	-9.50	neurotransmitter uptake	biological process	GO:0001504	30	3	18204	50	SLC1A3,SLC1A2,SLC6A11
7.933e-05	-9.44	mast_cell_neoplasm	COSMIC cancer mutations	mast_cell_neoplasm	248	6	16828	49	DGKB,GPC5,NPAS3,GRK5,NFIA,SORCS2
7.933e-05	-9.44	haematopoietic_and_lymphoid_tissue-haematopoietic_neoplasm-mast_cell_neoplasm	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue-haematopoietic_neoplasm-mast_cell_neoplasm	248	6	16828	49	GRK5,SORCS2,NFIA,DGKB,NPAS3,GPC5
7.937e-05	-9.44	prostate	COSMIC cancer mutations	prostate	13883	49	16828	49	NTRK2,SLC4A4,SLC39A12,SLC13A5,NPAS3,SOX5,ITPR2,GRK5,COL11A1,ITPK1,SNTB1,EGF,TNS3,PREX1,FGFRL1,PRDM16,NFIA,ZBTB20,PREX2,MSI2,NCKAP5,DGKB,QKI,NRCAM,PTN,PTPRZ1,LPIN2,FKBP5,TRPS1,RFX4,GPC5,USP6NL,SORCS2,APOA1,SLC1A3,NHSL1,FARP1,SLC1A2,CTNND2,FHOD3,CTBP1,LRIG1,ELOVL2,SLC6A11,ADAM12,GRIP1,RORA,AQP4,GPM6B
8.215e-05	-9.41	active monoatomic ion transmembrane transporter activity	molecular function	GO:0022853	274	6	18094	48	SLC6A11,SLC1A2,SLC39A12,SLC1A3,SLC13A5,SLC4A4
9.218e-05	-9.29	cell morphogenesis	biological process	GO:0000902	687	9	18204	50	CTNND2,NFIA,PTN,PREX2,PTPRZ1,NRCAM,SLC1A3,SLC39A12,FARP1
9.314e-05	-9.28	autonomic_ganglia-neuroblastoma	COSMIC cancer mutations	autonomic_ganglia-neuroblastoma	3970	24	16828	49	GPM6B,NFIA,AQP4,PRDM16,PREX1,FHOD3,TNS3,CTNND2,SLC1A2,SNTB1,EGF,USP6NL,SORCS2,COL11A1,TRPS1,RFX4,NPAS3,SLC13A5,LPIN2,PTPRZ1,NCKAP5,PREX2,SLC4A4,NTRK2
9.354e-05	-9.28	neuroblastoma	COSMIC cancer mutations	neuroblastoma	3971	24	16828	49	PTPRZ1,LPIN2,SLC13A5,NPAS3,TRPS1,RFX4,NTRK2,PREX2,SLC4A4,NCKAP5,PREX1,FHOD3,PRDM16,AQP4,NFIA,GPM6B,COL11A1,SORCS2,USP6NL,SNTB1,EGF,TNS3,SLC1A2,CTNND2
9.404e-05	-9.27	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-follicular_lymphoma	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-follicular_lymphoma	981	11	16828	49	ITPR2,FHOD3,GPC5,COL11A1,SORCS2,NCKAP5,PRDM16,DGKB,RORA,SOX5,CTNND2
9.646e-05	-9.25	central_nervous_system-cerebellum-primitive_neuroectodermal_tumour-medulloblastoma-SHH_subtype	COSMIC cancer mutations	central_nervous_system-cerebellum-primitive_neuroectodermal_tumour-medulloblastoma-SHH_subtype	653	9	16828	49	SORCS2,ITPR2,NTRK2,PTPRZ1,FHOD3,NRCAM,CTNND2,GRIP1,NPAS3
9.759e-05	-9.23	SHH_subtype	COSMIC cancer mutations	SHH_subtype	654	9	16828	49	NRCAM,CTNND2,GRIP1,NPAS3,SORCS2,ITPR2,NTRK2,PTPRZ1,FHOD3
1.006e-04	-9.20	organic anion transport	biological process	GO:0015711	398	7	18204	50	SLC13A5,SLC39A12,SLC1A3,NTRK2,SLC4A4,SLC6A11,SLC1A2
1.077e-04	-9.14	upper_aerodigestive_tract-mouth-carcinoma	COSMIC cancer mutations	upper_aerodigestive_tract-mouth-carcinoma	6426	32	16828	49	PRDM16,RORA,PREX1,FHOD3,CTBP1,SLC1A3,TNS3,SLC1A2,NHSL1,CTNND2,SNTB1,EGF,APOA1,GRK5,COL11A1,SORCS2,ITPK1,USP6NL,GPC5,TRPS1,SOX5,RFX4,SLC13A5,NPAS3,SLC39A12,NRCAM,NCKAP5,DGKB,QKI,PREX2,SLC4A4,ZBTB20
1.101e-04	-9.11	secondary active transmembrane transporter activity	molecular function	GO:0015291	289	6	18094	48	SLC4A4,SLC1A2,SLC13A5,SLC6A11,SLC1A3,SLC39A12
1.101e-04	-9.11	D-amino acid transport	biological process	GO:0042940	6	2	18204	50	SLC1A3,SLC1A2
1.101e-04	-9.11	L-aspartate import across plasma membrane	biological process	GO:0140009	6	2	18204	50	SLC1A2,SLC1A3
1.101e-04	-9.11	CARM1 (coactivator associated arginine methyltransferase 1)	protein interactions	10498	304	6	19454	49	NCKAP5,CTBP1,RORA,QKI,GRIP1,SNTB1
1.191e-04	-9.04	Pcbp1 (poly(rC) binding protein 1)	protein interactions	23983	38	3	19454	49	CTBP1,MSI2,QKI
1.317e-04	-8.94	skin-face-carcinoma-squamous_cell_carcinoma	COSMIC cancer mutations	skin-face-carcinoma-squamous_cell_carcinoma	2036	16	16828	49	PTPRZ1,FHOD3,PRDM16,GRIP1,SLC13A5,RORA,TRPS1,AQP4,ITPR2,GPC5,GRK5,PREX2,MSI2,COL11A1,EGF,FARP1
1.342e-04	-8.92	mouth	COSMIC cancer mutations	mouth	9004	39	16828	49	QKI,DGKB,NCKAP5,NRCAM,PTN,NTRK2,ZBTB20,SLC4A4,PREX2,SLC13A5,NPAS3,RFX4,TRPS1,SOX5,PTPRZ1,SLC39A12,EGF,APOA1,SNTB1,SLC1A2,NHSL1,CTNND2,SLC1A3,TNS3,GPC5,ITPR2,COL11A1,SORCS2,ITPK1,USP6NL,GRK5,RORA,PRDM16,FHOD3,CTBP1,PREX1,ADAM12,ELOVL2,LRIG1
1.367e-04	-8.90	follicular_lymphoma	COSMIC cancer mutations	follicular_lymphoma	1209	12	16828	49	FHOD3,PRDM16,RORA,SOX5,AQP4,ITPR2,GPC5,SORCS2,COL11A1,DGKB,NCKAP5,CTNND2
1.487e-04	-8.81	Na:dicarbo_symporter_sf	interpro domains	IPR036458	7	2	18521	50	SLC1A3,SLC1A2
1.487e-04	-8.81	Na-dicarboxylate_symporter	interpro domains	IPR001991	7	2	18521	50	SLC1A2,SLC1A3
1.487e-04	-8.81	Na-dicarboxylate_symporter_CS	interpro domains	IPR018107	7	2	18521	50	SLC1A2,SLC1A3
1.525e-04	-8.79	postsynaptic density	cellular component	GO:0014069	317	6	19108	49	ADGRB3,NRCAM,CTNND2,GRIP1,NTRK2,SORCS2
1.534e-04	-8.78	metal ion transmembrane transporter activity	molecular function	GO:0046873	442	7	18094	48	SLC6A11,SLC1A2,SLC39A12,ITPR2,SLC1A3,SLC13A5,SLC4A4
1.551e-04	-8.77	Sodium:dicarboxylate symporter	gene3d domains	1.10.3860.10	7	2	14470	40	SLC1A3,SLC1A2
1.610e-04	-8.73	SDF	pfam domains	PF00375	7	2	17795	50	SLC1A3,SLC1A2
1.949e-04	-8.54	cell morphogenesis involved in neuron differentiation	biological process	GO:0048667	443	7	18204	50	FARP1,NRCAM,SLC1A3,PTN,PREX2,PTPRZ1,CTNND2
1.963e-04	-8.54	neural precursor cell proliferation	biological process	GO:0061351	105	4	18204	50	EGF,RORA,NFIA,SOX5
1.992e-04	-8.52	asymmetric synapse	cellular component	GO:0032279	333	6	19108	49	SORCS2,NTRK2,GRIP1,CTNND2,NRCAM,ADGRB3
2.048e-04	-8.49	cell proliferation in external granule layer	biological process	GO:0021924	8	2	18204	50	EGF,RORA
2.048e-04	-8.49	cerebellar granule cell precursor proliferation	biological process	GO:0021930	8	2	18204	50	RORA,EGF
2.048e-04	-8.49	cell proliferation in hindbrain	biological process	GO:0021534	8	2	18204	50	RORA,EGF
2.071e-04	-8.48	right_upper_lobe	COSMIC cancer mutations	right_upper_lobe	10376	42	16828	49	SLC39A12,PTPRZ1,LPIN2,NPAS3,SLC13A5,SOX5,TRPS1,RFX4,ZBTB20,NTRK2,PREX2,SLC4A4,NCKAP5,DGKB,NRCAM,PTN,PREX1,CTBP1,FGFRL1,FHOD3,SLC6A11,LRIG1,ELOVL2,ADAM12,GRIP1,PRDM16,RORA,GPM6B,NFIA,ITPR2,GPC5,GRK5,SORCS2,USP6NL,COL11A1,APOA1,EGF,TNS3,SLC1A3,CTNND2,FARP1,SLC1A2
2.071e-04	-8.48	lung-right_upper_lobe-carcinoma-adenocarcinoma	COSMIC cancer mutations	lung-right_upper_lobe-carcinoma-adenocarcinoma	10376	42	16828	49	SLC13A5,NPAS3,TRPS1,SOX5,RFX4,PTPRZ1,SLC39A12,LPIN2,NCKAP5,DGKB,PTN,NRCAM,NTRK2,ZBTB20,PREX2,SLC4A4,GRIP1,PRDM16,RORA,NFIA,GPM6B,PREX1,FHOD3,FGFRL1,CTBP1,LRIG1,ELOVL2,SLC6A11,ADAM12,EGF,APOA1,SLC1A3,TNS3,SLC1A2,FARP1,CTNND2,ITPR2,GPC5,GRK5,COL11A1,SORCS2,USP6NL
2.071e-04	-8.48	EDTRNSPORT	prints domains	PR00173	7	2	5227	17	SLC1A2,SLC1A3
2.136e-04	-8.45	ELK3 (ETS transcription factor ELK3)	protein interactions	2004	117	4	19454	49	NFIA,CTBP1,PRDM16,TRPS1
2.282e-04	-8.39	bone-humerus-other-chondroblastoma	COSMIC cancer mutations	bone-humerus-other-chondroblastoma	301	6	16828	49	EGF,GPC5,FHOD3,NCKAP5,FARP1,SOX5
2.300e-04	-8.38	cervix-carcinoma-squamous_cell_carcinoma	COSMIC cancer mutations	cervix-carcinoma-squamous_cell_carcinoma	11789	45	16828	49	LPIN2,PTPRZ1,TRPS1,RFX4,FKBP5,PREX2,ZBTB20,NRCAM,DGKB,NCKAP5,QKI,LRIG1,ELOVL2,SLC6A11,ADAM12,FHOD3,CTBP1,GPM6B,GRIP1,RORA,USP6NL,SORCS2,GPC5,SLC1A3,FARP1,NHSL1,SLC1A2,CTNND2,SLC39A12,SOX5,SLC13A5,NPAS3,SLC4A4,NTRK2,PREX1,FGFRL1,NFIA,PRDM16,GRK5,COL11A1,ITPK1,ITPR2,TNS3,SNTB1,EGF
2.328e-04	-8.37	cervix	COSMIC cancer mutations	cervix	11793	45	16828	49	RORA,GRIP1,GPM6B,CTBP1,FHOD3,ADAM12,SLC6A11,ELOVL2,LRIG1,CTNND2,NHSL1,FARP1,SLC1A2,SLC1A3,GPC5,USP6NL,SORCS2,FKBP5,RFX4,TRPS1,PTPRZ1,LPIN2,QKI,NCKAP5,DGKB,NRCAM,ZBTB20,PREX2,PRDM16,NFIA,FGFRL1,PREX1,EGF,SNTB1,TNS3,ITPR2,ITPK1,COL11A1,GRK5,NPAS3,SLC13A5,SOX5,SLC39A12,NTRK2,SLC4A4
2.411e-04	-8.33	postsynaptic specialization	cellular component	GO:0099572	345	6	19108	49	NTRK2,NRCAM,GRIP1,ADGRB3,CTNND2,SORCS2
2.494e-04	-8.30	KLF3 (KLF transcription factor 3)	protein interactions	51274	225	5	19454	49	CTBP1,NFIA,TRPS1,SOX5,PRDM16
2.498e-04	-8.29	bone-Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour	COSMIC cancer mutations	bone-Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour	6023	30	16828	49	NCKAP5,NRCAM,ZBTB20,NTRK2,SLC4A4,PREX2,NPAS3,SLC13A5,SOX5,SLC39A12,PTPRZ1,LPIN2,EGF,CTNND2,FARP1,TNS3,SLC1A3,ITPR2,SORCS2,ITPK1,COL11A1,RORA,GRIP1,PRDM16,GPM6B,FGFRL1,FHOD3,PREX1,SLC6A11,LRIG1
2.521e-04	-8.29	adrenal_gland	COSMIC cancer mutations	adrenal_gland	2628	18	16828	49	SOX5,RFX4,GRIP1,SLC6A11,LRIG1,LPIN2,PTPRZ1,TNS3,NRCAM,CTNND2,FARP1,NHSL1,SLC1A2,NCKAP5,GRK5,COL11A1,ZBTB20,NTRK2
2.526e-04	-8.28	NA_DICARBOXYL_SYMP_2	prosite domains	PS00714	7	2	12186	43	SLC1A3,SLC1A2
2.526e-04	-8.28	NA_DICARBOXYL_SYMP_1	prosite domains	PS00713	7	2	12186	43	SLC1A3,SLC1A2
2.551e-04	-8.27	acidic amino acid transport	biological process	GO:0015800	45	3	18204	50	NTRK2,SLC1A3,SLC1A2
2.601e-04	-8.25	dendrite development	biological process	GO:0016358	113	4	18204	50	PREX2,FARP1,PTN,CTNND2
2.723e-04	-8.21	regulation of oligodendrocyte differentiation	biological process	GO:0048713	46	3	18204	50	QKI,PTPRZ1,PTN
2.723e-04	-8.21	positive regulation of glial cell differentiation	biological process	GO:0045687	46	3	18204	50	QKI,PTPRZ1,PTN
2.855e-04	-8.16	upper_aerodigestive_tract-larynx-carcinoma-squamous_cell_carcinoma	COSMIC cancer mutations	upper_aerodigestive_tract-larynx-carcinoma-squamous_cell_carcinoma	1946	15	16828	49	COL11A1,SLC4A4,SORCS2,ITPR2,ZBTB20,PTN,DGKB,NCKAP5,ADAM12,PREX1,SLC39A12,FHOD3,SOX5,RORA,NPAS3
2.877e-04	-8.15	positive regulation of developmental process	biological process	GO:0051094	1385	12	18204	50	EGF,SLC39A12,NRCAM,NTRK2,GRIP1,ADAM12,ADGRB3,QKI,PTPRZ1,PTN,SOX5,GPM6B
2.887e-04	-8.15	larynx	COSMIC cancer mutations	larynx	1948	15	16828	49	SOX5,NPAS3,RORA,ADAM12,FHOD3,SLC39A12,PREX1,PTN,DGKB,NCKAP5,SORCS2,COL11A1,SLC4A4,ZBTB20,ITPR2
2.946e-04	-8.13	central_nervous_system-brain-primitive_neuroectodermal_tumour-medulloblastoma-large_cell	COSMIC cancer mutations	central_nervous_system-brain-primitive_neuroectodermal_tumour-medulloblastoma-large_cell	1117	11	16828	49	FHOD3,GPC5,SORCS2,COL11A1,GRK5,QKI,PRDM16,NCKAP5,DGKB,SLC1A2,SOX5
3.165e-04	-8.06	central nervous system development	biological process	GO:0007417	995	10	18204	50	SLC1A2,MSI2,RORA,QKI,PTPRZ1,RFX4,GPM6B,EGF,NTRK2,NRCAM
3.260e-04	-8.03	neuron to neuron synapse	cellular component	GO:0098984	365	6	19108	49	SORCS2,CTNND2,NTRK2,GRIP1,ADGRB3,NRCAM
3.281e-04	-8.02	cellular response to cocaine	biological process	GO:0071314	10	2	18204	50	SLC1A2,SLC1A3
3.281e-04	-8.02	action potential propagation	biological process	GO:0098870	10	2	18204	50	NRCAM,NTRK2
3.281e-04	-8.02	neuronal action potential propagation	biological process	GO:0019227	10	2	18204	50	NRCAM,NTRK2
3.283e-04	-8.02	glial cell differentiation	biological process	GO:0010001	219	5	18204	50	NTRK2,GPM6B,NFIA,PTPRZ1,QKI
3.424e-04	-7.98	neuron projection morphogenesis	biological process	GO:0048812	486	7	18204	50	NRCAM,SLC39A12,FARP1,CTNND2,PTN,PREX2,PTPRZ1
3.471e-04	-7.97	serous_carcinoma	COSMIC cancer mutations	serous_carcinoma	10987	43	16828	49	FGFRL1,FHOD3,CTBP1,PREX1,ADAM12,LRIG1,ELOVL2,SLC6A11,RORA,PRDM16,GRIP1,GPM6B,GPC5,ITPR2,COL11A1,ITPK1,USP6NL,SORCS2,GRK5,EGF,SNTB1,SLC1A2,NHSL1,FARP1,CTNND2,SLC1A3,TNS3,PTPRZ1,SLC39A12,LPIN2,FKBP5,NPAS3,TRPS1,SOX5,NTRK2,ZBTB20,SLC4A4,PREX2,MSI2,QKI,DGKB,NCKAP5,NRCAM
3.642e-04	-7.92	plasma membrane bounded cell projection morphogenesis	biological process	GO:0120039	491	7	18204	50	CTNND2,PTPRZ1,PREX2,PTN,SLC39A12,NRCAM,FARP1
3.870e-04	-7.86	cell projection morphogenesis	biological process	GO:0048858	496	7	18204	50	PTPRZ1,FARP1,PREX2,PTN,CTNND2,SLC39A12,NRCAM
3.977e-04	-7.83	PRNP (prion protein (Kanno blood group))	protein interactions	5621	1118	10	19454	49	NHSL1,SLC1A3,QKI,TRPS1,MSI2,AQP4,SLC4A4,ITPK1,PTPRZ1,COL11A1
4.003e-04	-7.82	L-aspartate transmembrane transport	biological process	GO:0070778	11	2	18204	50	SLC1A2,SLC1A3
4.003e-04	-7.82	L-glutamate import across plasma membrane	biological process	GO:0098712	11	2	18204	50	SLC1A3,SLC1A2
4.010e-04	-7.82	NFIB (nuclear factor I B)	protein interactions	4781	138	4	19454	49	GRK5,SOX5,TRPS1,NFIA
4.244e-04	-7.76	Neurotransmitter Release Cycle	REACTOME pathways	R-HSA-112310	51	3	10285	30	SLC1A2,SLC1A3,SLC6A11
4.404e-04	-7.73	Ig_I-set	interpro domains	IPR013098	132	4	18521	50	NRCAM,NTRK2,LRIG1,FGFRL1
4.698e-04	-7.66	amino acid transport	biological process	GO:0006865	132	4	18204	50	SLC1A3,SLC1A2,NTRK2,SLC6A11
4.724e-04	-7.66	stomach-carcinoma-diffuse_adenocarcinoma	COSMIC cancer mutations	stomach-carcinoma-diffuse_adenocarcinoma	4383	24	16828	49	CTNND2,FARP1,NHSL1,SLC1A3,PTN,QKI,DGKB,SNTB1,NCKAP5,SORCS2,COL11A1,PREX2,RFX4,SOX5,TRPS1,FKBP5,GRIP1,ADAM12,SLC6A11,ELOVL2,FHOD3,SLC39A12,PREX1,PTPRZ1
4.724e-04	-7.66	diffuse_adenocarcinoma	COSMIC cancer mutations	diffuse_adenocarcinoma	4383	24	16828	49	COL11A1,SORCS2,PREX2,QKI,DGKB,NCKAP5,SNTB1,FARP1,NHSL1,CTNND2,PTN,SLC1A3,FHOD3,PREX1,PTPRZ1,SLC39A12,ADAM12,ELOVL2,SLC6A11,FKBP5,GRIP1,RFX4,SOX5,TRPS1
4.781e-04	-7.65	stomach-adenocarcinoma	COSMIC cancer mutations	stomach-adenocarcinoma	4101	23	16828	49	SLC4A4,COL11A1,PREX2,GPC5,ITPR2,SLC1A2,CTNND2,PTN,NRCAM,TNS3,EGF,QKI,ADAM12,LRIG1,SLC6A11,FHOD3,PREX1,SLC39A12,RFX4,TRPS1,FKBP5,RORA,GRIP1
4.899e-04	-7.62	positive regulation of multicellular organismal process	biological process	GO:0051240	1691	13	18204	50	SLC39A12,NTRK2,PRDM16,ADAM12,PTN,GPM6B,EGF,ZBTB20,ADGRB3,RORA,PTPRZ1,QKI,SOX5
5.016e-04	-7.60	regulation of cell projection organization	biological process	GO:0031344	683	8	18204	50	NRCAM,NTRK2,SLC39A12,PTN,ADGRB3,PREX1,USP6NL,GRIP1
5.114e-04	-7.58	organic acid transmembrane transport	biological process	GO:1903825	135	4	18204	50	SLC6A11,SLC1A3,SLC13A5,SLC1A2
5.115e-04	-7.58	I-set	pfam domains	PF07679	132	4	17795	50	LRIG1,FGFRL1,NTRK2,NRCAM
5.194e-04	-7.56	muscle structure development	biological process	GO:0061061	521	7	18204	50	FHOD3,COL11A1,ADAM12,ADGRB3,RORA,QKI,FGFRL1
5.266e-04	-7.55	inorganic molecular entity transmembrane transporter activity	molecular function	GO:0015318	714	8	18094	48	AQP4,SLC6A11,SLC1A2,SLC1A3,ITPR2,SLC39A12,SLC4A4,SLC13A5
5.276e-04	-7.55	monoatomic cation:bicarbonate symporter activity	molecular function	GO:0140410	13	2	18094	48	SLC4A4,SLC39A12
5.357e-04	-7.53	NR3C1 (nuclear receptor subfamily 3 group C member 1)	protein interactions	2908	950	9	19454	49	PREX1,SLC1A3,APOA1,NFIA,GRIP1,TRPS1,FKBP5,CTNND2,ZBTB20
5.522e-04	-7.50	neuron projection development	biological process	GO:0031175	693	8	18204	50	CTNND2,PTN,PREX2,GPM6B,PTPRZ1,NRCAM,SLC39A12,FARP1
5.566e-04	-7.49	ovary-carcinoma-serous_carcinoma	COSMIC cancer mutations	ovary-carcinoma-serous_carcinoma	10710	42	16828	49	GPM6B,GRIP1,PRDM16,RORA,ELOVL2,LRIG1,SLC6A11,ADAM12,PREX1,FHOD3,FGFRL1,CTBP1,SLC1A3,TNS3,SLC1A2,NHSL1,FARP1,CTNND2,SNTB1,GRK5,COL11A1,SORCS2,ITPK1,USP6NL,ITPR2,GPC5,SOX5,TRPS1,FKBP5,NPAS3,LPIN2,PTPRZ1,SLC39A12,NRCAM,DGKB,NCKAP5,QKI,PREX2,MSI2,SLC4A4,NTRK2,ZBTB20
6.057e-04	-7.41	prostate-adenoma	COSMIC cancer mutations	prostate-adenoma	1634	13	16828	49	FARP1,SOX5,PTN,NPAS3,EGF,ADAM12,COL11A1,SLC6A11,FHOD3,GPC5,ZBTB20,PREX1,PTPRZ1
6.145e-04	-7.39	L-glutamate transmembrane transporter activity	molecular function	GO:0005313	14	2	18094	48	SLC1A2,SLC1A3
6.239e-04	-7.38	nasopharyngeal_carcinoma	COSMIC cancer mutations	nasopharyngeal_carcinoma	1425	12	16828	49	FGFRL1,ADAM12,NFIA,RFX4,NTRK2,SLC4A4,PREX2,QKI,NCKAP5,NHSL1,SLC1A2,CTNND2
6.239e-04	-7.38	upper_aerodigestive_tract-pharynx-carcinoma-nasopharyngeal_carcinoma	COSMIC cancer mutations	upper_aerodigestive_tract-pharynx-carcinoma-nasopharyngeal_carcinoma	1425	12	16828	49	SLC4A4,ADAM12,PREX2,FGFRL1,NTRK2,RFX4,NFIA,NHSL1,SLC1A2,CTNND2,QKI,NCKAP5
6.440e-04	-7.35	PDZ	interpro domains	IPR001478	146	4	18521	50	PREX2,GRIP1,PREX1,SNTB1
6.850e-04	-7.29	scalp	COSMIC cancer mutations	scalp	2110	15	16828	49	PREX2,COL11A1,SLC4A4,GPC5,NRCAM,PTN,FARP1,SLC6A11,ADAM12,PTPRZ1,PREX1,SOX5,TRPS1,NFIA,RORA
6.950e-04	-7.27	PDZ_sf	interpro domains	IPR036034	149	4	18521	50	PREX1,PREX2,GRIP1,SNTB1
7.397e-04	-7.21	-	gene3d domains	2.30.42.10	149	4	14470	40	SNTB1,GRIP1,PREX2,PREX1
7.686e-04	-7.17	adenoma	COSMIC cancer mutations	adenoma	2873	18	16828	49	FHOD3,PREX1,PTPRZ1,ADAM12,SLC6A11,NPAS3,PRDM16,GRIP1,SOX5,GPC5,ZBTB20,NTRK2,COL11A1,EGF,NCKAP5,CTNND2,FARP1,PTN
7.853e-04	-7.15	EGR2 (early growth response 2)	protein interactions	1959	165	4	19454	49	SOX5,TRPS1,PRDM16,NFIA
8.075e-04	-7.12	kidney-carcinoma-renal_cell_carcinoma	COSMIC cancer mutations	kidney-carcinoma-renal_cell_carcinoma	4535	24	16828	49	GRK5,PREX2,MSI2,USP6NL,NTRK2,ITPR2,FARP1,CTNND2,DGKB,SNTB1,QKI,LPIN2,LRIG1,ADAM12,PREX1,PTPRZ1,SLC39A12,SOX5,TRPS1,GPM6B,PRDM16,RORA,SLC13A5,FKBP5
8.075e-04	-7.12	renal_cell_carcinoma	COSMIC cancer mutations	renal_cell_carcinoma	4535	24	16828	49	NTRK2,PREX2,MSI2,DGKB,QKI,PTPRZ1,SLC39A12,LPIN2,SLC13A5,FKBP5,SOX5,TRPS1,ITPR2,GRK5,USP6NL,SNTB1,FARP1,CTNND2,PREX1,LRIG1,ADAM12,PRDM16,RORA,GPM6B
8.632e-04	-7.05	inorganic cation transmembrane transporter activity	molecular function	GO:0022890	589	7	18094	48	SLC1A3,ITPR2,SLC39A12,SLC4A4,SLC13A5,SLC6A11,SLC1A2
8.923e-04	-7.02	DH-domain	interpro domains	IPR000219	70	3	18521	50	PREX2,PREX1,FARP1
8.960e-04	-7.02	skin-leg-malignant_melanoma-nodular	COSMIC cancer mutations	skin-leg-malignant_melanoma-nodular	258	5	16828	49	GRK5,SLC4A4,COL11A1,PTPRZ1,EGF
9.223e-04	-6.99	gliogenesis	biological process	GO:0042063	275	5	18204	50	NFIA,GPM6B,PTPRZ1,QKI,NTRK2
9.254e-04	-6.99	kidney-carcinoma	COSMIC cancer mutations	kidney-carcinoma	3720	21	16828	49	PREX1,PTPRZ1,ADAM12,LPIN2,LRIG1,RORA,FKBP5,PRDM16,TRPS1,SOX5,ITPR2,NTRK2,USP6NL,MSI2,PREX2,GRK5,QKI,SNTB1,DGKB,CTNND2,FARP1
9.299e-04	-6.98	DBL_dom_sf	interpro domains	IPR035899	71	3	18521	50	FARP1,PREX2,PREX1
9.794e-04	-6.93	viral genome replication	biological process	GO:0019079	17	2	18204	50	NFIA,CTBP1
9.819e-04	-6.93	Dbl homology (DH) domain	gene3d domains	1.20.900.10	71	3	14470	40	PREX1,PREX2,FARP1
1.001e-03	-6.91	RhoGEF	pfam domains	PF00621	70	3	17795	50	PREX1,FARP1,PREX2
1.026e-03	-6.88	acidic amino acid transmembrane transporter activity	molecular function	GO:0015172	18	2	18094	48	SLC1A2,SLC1A3
1.064e-03	-6.85	pleura	COSMIC cancer mutations	pleura	4914	25	16828	49	ITPR2,USP6NL,GRK5,SNTB1,CTNND2,FARP1,FGFRL1,FHOD3,PREX1,ADAM12,LRIG1,RORA,PRDM16,GPM6B,NTRK2,MSI2,PREX2,QKI,DGKB,NCKAP5,PTPRZ1,LPIN2,FKBP5,TRPS1,SOX5
1.066e-03	-6.84	lung-left_upper_lobe-carcinoma-adenocarcinoma	COSMIC cancer mutations	lung-left_upper_lobe-carcinoma-adenocarcinoma	556	7	16828	49	CTNND2,TRPS1,DGKB,SLC4A4,SLC6A11,PREX1,NTRK2
1.071e-03	-6.84	astrocyte projection	cellular component	GO:0097449	19	2	19108	49	SLC1A2,AQP4
1.082e-03	-6.83	active transmembrane transporter activity	molecular function	GO:0022804	444	6	18094	48	SLC6A11,SLC1A2,SLC1A3,SLC39A12,SLC4A4,SLC13A5
1.089e-03	-6.82	left_upper_lobe	COSMIC cancer mutations	left_upper_lobe	558	7	16828	49	SLC6A11,TRPS1,CTNND2,SLC4A4,DGKB,PREX1,NTRK2
1.102e-03	-6.81	positive regulation of gliogenesis	biological process	GO:0014015	74	3	18204	50	PTN,QKI,PTPRZ1
1.151e-03	-6.77	muscle cell differentiation	biological process	GO:0042692	289	5	18204	50	ADAM12,ADGRB3,FHOD3,RORA,QKI
1.181e-03	-6.74	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-chronic_lymphocytic_leukaemia-small_lymphocytic_lymphoma	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-chronic_lymphocytic_leukaemia-small_lymphocytic_lymphoma	3511	20	16828	49	TNS3,NRCAM,SLC1A3,CTNND2,DGKB,SNTB1,NCKAP5,EGF,MSI2,PREX2,ITPK1,COL11A1,SLC4A4,NTRK2,GPC5,GRIP1,NPAS3,PTPRZ1,FGFRL1,FHOD3
1.181e-03	-6.74	chronic_lymphocytic_leukaemia-small_lymphocytic_lymphoma	COSMIC cancer mutations	chronic_lymphocytic_leukaemia-small_lymphocytic_lymphoma	3511	20	16828	49	FHOD3,FGFRL1,PTPRZ1,NPAS3,GRIP1,GPC5,NTRK2,SLC4A4,COL11A1,ITPK1,PREX2,MSI2,EGF,NCKAP5,SNTB1,DGKB,CTNND2,SLC1A3,NRCAM,TNS3
1.201e-03	-6.72	KLF12 (KLF transcription factor 12)	protein interactions	11278	185	4	19454	49	PRDM16,TRPS1,NFIA,CTBP1
1.227e-03	-6.70	cartilage condensation	biological process	GO:0001502	19	2	18204	50	COL11A1,SOX5
1.240e-03	-6.69	FXYD6 (FXYD domain containing ion transport regulator 6)	protein interactions	53826	84	3	19454	49	GPC5,ELOVL2,SLC39A12
1.265e-03	-6.67	adenoid_cystic_carcinoma	COSMIC cancer mutations	adenoid_cystic_carcinoma	1123	10	16828	49	GPM6B,CTNND2,NRCAM,RORA,SLC13A5,EGF,PRDM16,ITPK1,GRK5,NTRK2
1.277e-03	-6.66	monoatomic cation transmembrane transporter activity	molecular function	GO:0008324	630	7	18094	48	SLC1A3,ITPR2,SLC39A12,SLC4A4,SLC13A5,SLC6A11,SLC1A2
1.280e-03	-6.66	positive regulation of nervous system development	biological process	GO:0051962	296	5	18204	50	PTN,QKI,PTPRZ1,NTRK2,ADGRB3
1.283e-03	-6.66	positive regulation of carbohydrate metabolic process	biological process	GO:0045913	78	3	18204	50	EGF,ZBTB20,SLC4A4
1.289e-03	-6.65	regulation of neuron projection development	biological process	GO:0010975	443	6	18204	50	NTRK2,PREX1,NRCAM,ADGRB3,SLC39A12,PTN
1.299e-03	-6.65	carboxylic acid transport	biological process	GO:0046942	297	5	18204	50	SLC13A5,SLC1A2,SLC1A3,NTRK2,SLC6A11
1.313e-03	-6.64	SLC-mediated transmembrane transport	REACTOME pathways	R-HSA-425407	287	5	10285	30	SLC4A4,SLC6A11,SLC1A3,SLC13A5,SLC1A2
1.314e-03	-6.63	haematopoietic_and_lymphoid_tissue-lymph_node-lymphoid_neoplasm-diffuse_large_B_cell_lymphoma	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue-lymph_node-lymphoid_neoplasm-diffuse_large_B_cell_lymphoma	748	8	16828	49	ITPR2,NTRK2,FHOD3,GRK5,TRPS1,SLC1A3,SOX5,CTNND2
1.317e-03	-6.63	prostate-carcinoma-adenocarcinoma	COSMIC cancer mutations	prostate-carcinoma-adenocarcinoma	12379	45	16828	49	GPC5,USP6NL,SORCS2,SLC1A2,NHSL1,FARP1,CTNND2,SLC1A3,FHOD3,CTBP1,ADAM12,ELOVL2,LRIG1,SLC6A11,RORA,GRIP1,AQP4,GPM6B,ZBTB20,PREX2,QKI,NCKAP5,DGKB,NRCAM,PTN,PTPRZ1,FKBP5,RFX4,TRPS1,ITPR2,COL11A1,ITPK1,GRK5,EGF,SNTB1,TNS3,FGFRL1,PREX1,PRDM16,NFIA,NTRK2,SLC39A12,SLC13A5,NPAS3,SOX5
1.318e-03	-6.63	organic acid transport	biological process	GO:0015849	298	5	18204	50	SLC1A2,SLC13A5,SLC1A3,NTRK2,SLC6A11
1.331e-03	-6.62	regulation of glial cell differentiation	biological process	GO:0045685	79	3	18204	50	PTPRZ1,QKI,PTN
1.361e-03	-6.60	aspartate transmembrane transport	biological process	GO:0015810	20	2	18204	50	SLC1A2,SLC1A3
1.390e-03	-6.58	Dusp14 (dual specificity phosphatase 14)	protein interactions	56405	22	2	19454	49	QKI,CTBP1
1.408e-03	-6.57	salivary_gland	COSMIC cancer mutations	salivary_gland	1139	10	16828	49	NTRK2,ITPK1,GRK5,SLC13A5,EGF,RORA,PRDM16,CTNND2,GPM6B,NRCAM
1.418e-03	-6.56	DYRK1B (dual specificity tyrosine phosphorylation regulated kinase 1B)	protein interactions	9149	88	3	19454	49	LPIN2,FKBP5,CTBP1
1.425e-03	-6.55	behavior	biological process	GO:0007610	619	7	18204	50	NTRK2,SLC1A3,PTN,PREX2,PTPRZ1,ADGRB3,SLC1A2
1.452e-03	-6.54	GDS_CDC24_CS	interpro domains	IPR001331	21	2	18521	50	PREX2,PREX1
1.456e-03	-6.53	lower_third	COSMIC cancer mutations	lower_third	7961	34	16828	49	ITPR2,GPC5,COL11A1,SORCS2,SNTB1,APOA1,TNS3,FARP1,CTNND2,PREX1,FHOD3,LRIG1,SLC6A11,ADAM12,PRDM16,GRIP1,RORA,AQP4,GPM6B,NTRK2,ZBTB20,PREX2,SLC4A4,DGKB,NCKAP5,QKI,PTPRZ1,SLC39A12,LPIN2,SLC13A5,FKBP5,NPAS3,TRPS1,SOX5
1.478e-03	-6.52	carboxylic acid transmembrane transporter activity	molecular function	GO:0046943	186	4	18094	48	SLC6A11,SLC1A3,SLC13A5,SLC1A2
1.502e-03	-6.50	positive regulation of glycolytic process	biological process	GO:0045821	21	2	18204	50	ZBTB20,SLC4A4
1.502e-03	-6.50	positive regulation of purine nucleotide catabolic process	biological process	GO:0033123	21	2	18204	50	ZBTB20,SLC4A4
1.502e-03	-6.50	positive regulation of nucleotide catabolic process	biological process	GO:0030813	21	2	18204	50	ZBTB20,SLC4A4
1.502e-03	-6.50	positive regulation of stem cell differentiation	biological process	GO:2000738	21	2	18204	50	PTN,SOX5
1.502e-03	-6.50	cell aggregation	biological process	GO:0098743	21	2	18204	50	SOX5,COL11A1
1.507e-03	-6.50	organic acid transmembrane transporter activity	molecular function	GO:0005342	187	4	18094	48	SLC6A11,SLC1A3,SLC1A2,SLC13A5
1.519e-03	-6.49	enzyme-linked receptor protein signaling pathway	biological process	GO:0007167	626	7	18204	50	NFIA,PTN,FGFRL1,FARP1,NTRK2,APOA1,EGF
1.520e-03	-6.49	Rbm38 (RNA binding motif protein 38)	protein interactions	56190	23	2	19454	49	QKI,MSI2
1.570e-03	-6.46	DEP	pfam domains	PF00610	21	2	17795	50	PREX2,PREX1
1.573e-03	-6.45	PDZ	prosite domains	PS50106	143	4	12186	43	PREX2,GRIP1,PREX1,SNTB1
1.582e-03	-6.45	ERK Pathway in Huntington's Disease	WikiPathways	WP3853	14	2	5310	23	NTRK2,EGF
1.587e-03	-6.45	regulation of carbohydrate metabolic process	biological process	GO:0006109	183	4	18204	50	EGF,ZBTB20,SLC4A4,RORA
1.594e-03	-6.44	DEP_dom	interpro domains	IPR000591	22	2	18521	50	PREX1,PREX2
1.615e-03	-6.43	oesophagus-lower_third-carcinoma-adenocarcinoma	COSMIC cancer mutations	oesophagus-lower_third-carcinoma-adenocarcinoma	6302	29	16828	49	LPIN2,PTPRZ1,SLC39A12,SOX5,TRPS1,FKBP5,NPAS3,PREX2,NTRK2,ZBTB20,QKI,NCKAP5,DGKB,ADAM12,SLC6A11,FHOD3,PREX1,AQP4,GPM6B,RORA,GRIP1,COL11A1,SORCS2,GPC5,ITPR2,FARP1,CTNND2,APOA1,SNTB1
1.644e-03	-6.41	oligodendrocyte differentiation	biological process	GO:0048709	85	3	18204	50	NTRK2,GPM6B,PTPRZ1
1.649e-03	-6.41	neurotransmitter reuptake	biological process	GO:0098810	22	2	18204	50	SLC6A11,SLC1A2
1.652e-03	-6.41	PDZ	smart domains	SM00228	143	4	9717	35	GRIP1,PREX2,SNTB1,PREX1
1.659e-03	-6.40	pancreas-carcinoma	COSMIC cancer mutations	pancreas-carcinoma	14770	49	16828	49	ZBTB20,MSI2,PREX2,QKI,DGKB,NCKAP5,PTN,NRCAM,PTPRZ1,LPIN2,FKBP5,RFX4,TRPS1,GPC5,USP6NL,SORCS2,APOA1,CTNND2,FARP1,NHSL1,SLC1A2,SLC1A3,CTBP1,FHOD3,ADAM12,SLC6A11,ELOVL2,LRIG1,RORA,GRIP1,GPM6B,AQP4,NTRK2,SLC4A4,SLC39A12,NPAS3,SLC13A5,SOX5,ITPR2,ITPK1,COL11A1,GRK5,EGF,SNTB1,TNS3,FGFRL1,PREX1,PRDM16,NFIA
1.662e-03	-6.40	DMRTB1 (DMRT like family B with proline rich C-terminal 1)	protein interactions	63948	93	3	19454	49	CTBP1,MSI2,QKI
1.667e-03	-6.40	positive regulation of biological process	biological process	GO:0048518	6326	28	18204	50	ZBTB20,SLC1A2,ADGRB3,QKI,SLC39A12,SLC1A3,GPC5,CTBP1,PRDM16,RFX4,GPM6B,PTN,EGF,APOA1,NPAS3,SLC4A4,FARP1,LPIN2,RORA,PTPRZ1,SOX5,NTRK2,NRCAM,GRK5,GRIP1,PREX1,ADAM12,NFIA
1.689e-03	-6.38	skin-scalp-carcinoma-squamous_cell_carcinoma	COSMIC cancer mutations	skin-scalp-carcinoma-squamous_cell_carcinoma	1596	12	16828	49	COL11A1,SLC4A4,GPC5,FARP1,PTN,NRCAM,ADAM12,PREX1,PTPRZ1,SOX5,TRPS1,RORA
1.700e-03	-6.38	vascular transport	biological process	GO:0010232	86	3	18204	50	SLC1A3,SLC1A2,SLC4A4
1.700e-03	-6.38	transport across blood-brain barrier	biological process	GO:0150104	86	3	18204	50	SLC4A4,SLC1A2,SLC1A3
1.702e-03	-6.38	abdomen	COSMIC cancer mutations	abdomen	603	7	16828	49	CTNND2,PRDM16,COL11A1,SLC6A11,LRIG1,PREX2,ITPR2
1.758e-03	-6.34	right_lower_lobe	COSMIC cancer mutations	right_lower_lobe	5692	27	16828	49	PREX1,FHOD3,CTBP1,LRIG1,SLC6A11,ADAM12,PRDM16,GRIP1,GPM6B,ITPR2,GPC5,GRK5,COL11A1,USP6NL,SLC1A3,CTNND2,PTPRZ1,SLC39A12,NPAS3,SOX5,TRPS1,NTRK2,SLC4A4,NCKAP5,DGKB,NRCAM,PTN
1.758e-03	-6.34	lung-right_lower_lobe-carcinoma-adenocarcinoma	COSMIC cancer mutations	lung-right_lower_lobe-carcinoma-adenocarcinoma	5692	27	16828	49	ITPR2,GPC5,GRK5,USP6NL,COL11A1,SLC1A3,CTNND2,PREX1,CTBP1,FHOD3,SLC6A11,LRIG1,ADAM12,GRIP1,PRDM16,GPM6B,NTRK2,SLC4A4,NCKAP5,DGKB,PTN,NRCAM,SLC39A12,PTPRZ1,NPAS3,SOX5,TRPS1
1.777e-03	-6.33	pleura-mesothelioma	COSMIC cancer mutations	pleura-mesothelioma	4189	22	16828	49	PREX1,LRIG1,ADAM12,PRDM16,RORA,GPM6B,ITPR2,GRK5,USP6NL,SNTB1,FARP1,CTNND2,PTPRZ1,LPIN2,FKBP5,SOX5,TRPS1,NTRK2,PREX2,MSI2,DGKB,QKI
1.808e-03	-6.32	lung-carcinoma-small_cell_carcinoma	COSMIC cancer mutations	lung-carcinoma-small_cell_carcinoma	9908	39	16828	49	SLC4A4,MSI2,PREX2,NTRK2,NRCAM,PTN,QKI,DGKB,LPIN2,SLC39A12,PTPRZ1,RFX4,TRPS1,SOX5,NPAS3,SLC13A5,FKBP5,ITPK1,USP6NL,COL11A1,GRK5,GPC5,ITPR2,CTNND2,FARP1,TNS3,APOA1,EGF,SNTB1,ADAM12,LRIG1,FGFRL1,FHOD3,PREX1,GPM6B,NFIA,RORA,GRIP1,PRDM16
1.808e-03	-6.32	nucleoside-triphosphatase regulator activity	molecular function	GO:0060589	491	6	18094	48	PREX2,PREX1,USP6NL,ADGRB3,EGF,FARP1
1.808e-03	-6.32	GTPase regulator activity	molecular function	GO:0030695	491	6	18094	48	EGF,PREX1,USP6NL,ADGRB3,FARP1,PREX2
1.828e-03	-6.30	RhoGEF	smart domains	SM00325	68	3	9717	35	PREX1,PREX2,FARP1
1.831e-03	-6.30	small_cell_carcinoma	COSMIC cancer mutations	small_cell_carcinoma	9913	39	16828	49	APOA1,EGF,SNTB1,CTNND2,FARP1,TNS3,GPC5,ITPR2,USP6NL,ITPK1,COL11A1,GRK5,RORA,GRIP1,PRDM16,GPM6B,NFIA,FHOD3,FGFRL1,PREX1,ADAM12,LRIG1,QKI,DGKB,NRCAM,PTN,NTRK2,SLC4A4,MSI2,PREX2,NPAS3,FKBP5,SLC13A5,RFX4,SOX5,TRPS1,SLC39A12,PTPRZ1,LPIN2
1.900e-03	-6.27	DH_2	prosite domains	PS50010	70	3	12186	43	PREX1,FARP1,PREX2
1.909e-03	-6.26	breast-carcinoma-ductolobular_carcinoma	COSMIC cancer mutations	breast-carcinoma-ductolobular_carcinoma	1619	12	16828	49	NRCAM,CTNND2,FARP1,DGKB,QKI,RORA,PREX2,ADAM12,COL11A1,SLC39A12,PTPRZ1,FHOD3
1.909e-03	-6.26	ductolobular_carcinoma	COSMIC cancer mutations	ductolobular_carcinoma	1619	12	16828	49	QKI,DGKB,CTNND2,FARP1,NRCAM,COL11A1,PREX2,RORA,FHOD3,SLC39A12,PTPRZ1,ADAM12
1.913e-03	-6.26	human chr6q12-q13	chromosome location	human chr6q12-q13	1	1	26134	50	ADGRB3
1.925e-03	-6.25	kidney-carcinoma-papillary_renal_cell_carcinoma	COSMIC cancer mutations	kidney-carcinoma-papillary_renal_cell_carcinoma	6364	29	16828	49	FGFRL1,FHOD3,PREX1,ADAM12,LRIG1,RORA,PRDM16,NFIA,GPC5,ITPR2,COL11A1,ITPK1,GRK5,EGF,SNTB1,FARP1,CTNND2,TNS3,PTPRZ1,LPIN2,SLC13A5,RFX4,SOX5,NTRK2,ZBTB20,SLC4A4,PREX2,NCKAP5,NRCAM
1.925e-03	-6.25	papillary_renal_cell_carcinoma	COSMIC cancer mutations	papillary_renal_cell_carcinoma	6364	29	16828	49	SLC13A5,SOX5,RFX4,PTPRZ1,LPIN2,NCKAP5,NRCAM,ZBTB20,NTRK2,PREX2,SLC4A4,PRDM16,RORA,NFIA,PREX1,FGFRL1,FHOD3,LRIG1,ADAM12,SNTB1,EGF,TNS3,CTNND2,FARP1,ITPR2,GPC5,GRK5,ITPK1,COL11A1
1.943e-03	-6.24	TSSK2 (testis specific serine kinase 2)	protein interactions	23617	26	2	19454	49	FKBP5,APOA1
1.952e-03	-6.24	regulation of multicellular organismal development	biological process	GO:2000026	1484	11	18204	50	ADGRB3,ADAM12,QKI,TRPS1,PTPRZ1,SOX5,GPM6B,PTN,SLC39A12,EGF,NTRK2
1.957e-03	-6.24	bone-femur-other-chondroblastoma	COSMIC cancer mutations	bone-femur-other-chondroblastoma	183	4	16828	49	GPC5,PREX1,NCKAP5,SNTB1
2.095e-03	-6.17	MBNL2 (muscleblind like splicing regulator 2)	protein interactions	10150	27	2	19454	49	MSI2,QKI
2.127e-03	-6.15	large_cell	COSMIC cancer mutations	large_cell	14845	49	16828	49	GPC5,USP6NL,SORCS2,APOA1,CTNND2,FARP1,NHSL1,SLC1A2,SLC1A3,CTBP1,FHOD3,ADAM12,SLC6A11,ELOVL2,LRIG1,RORA,GRIP1,GPM6B,AQP4,ZBTB20,MSI2,PREX2,QKI,NCKAP5,DGKB,NRCAM,PTN,PTPRZ1,LPIN2,FKBP5,RFX4,TRPS1,ITPR2,ITPK1,COL11A1,GRK5,EGF,SNTB1,TNS3,FGFRL1,PREX1,PRDM16,NFIA,NTRK2,SLC4A4,SLC39A12,NPAS3,SLC13A5,SOX5
2.130e-03	-6.15	L-glutamate transmembrane transport	biological process	GO:0015813	25	2	18204	50	SLC1A2,SLC1A3
2.146e-03	-6.14	synapse organization	biological process	GO:0050808	333	5	18204	50	FARP1,NFIA,CTNND2,NRCAM,ADGRB3
2.149e-03	-6.14	central_nervous_system-brain-glioma-astrocytoma_Grade_III	COSMIC cancer mutations	central_nervous_system-brain-glioma-astrocytoma_Grade_III	1419	11	16828	49	PRDM16,NCKAP5,GRIP1,SNTB1,FARP1,TNS3,GPC5,FHOD3,SLC39A12,COL11A1,GRK5
2.161e-03	-6.14	regulation of plasma membrane bounded cell projection organization	biological process	GO:0120035	666	7	18204	50	NRCAM,NTRK2,SLC39A12,PTN,ADGRB3,PREX1,USP6NL
2.181e-03	-6.13	Glutamate Neurotransmitter Release Cycle	REACTOME pathways	R-HSA-210500	24	2	10285	30	SLC1A3,SLC1A2
2.203e-03	-6.12	lung-carcinoma	COSMIC cancer mutations	lung-carcinoma	4255	22	16828	49	GPM6B,PRDM16,RORA,LRIG1,ADAM12,PREX1,CTNND2,FARP1,SNTB1,GRK5,USP6NL,ITPR2,TRPS1,SOX5,FKBP5,LPIN2,PTPRZ1,DGKB,QKI,MSI2,PREX2,NTRK2
2.214e-03	-6.11	postsynaptic density membrane	cellular component	GO:0098839	101	3	19108	49	NRCAM,ADGRB3,SORCS2
2.226e-03	-6.11	membrane	cellular component	GO:0016020	9220	34	19108	49	LRIG1,APOA1,SLC4A4,ITPK1,GPM6B,AQP4,FGFRL1,PREX1,GRK5,NTRK2,SLC13A5,SORCS2,SNTB1,SLC6A11,USP6NL,FKBP5,CTNND2,ITPR2,SLC1A3,SLC39A12,GPC5,SLC1A2,FARP1,PTN,PTPRZ1,DGKB,GRIP1,ADAM12,ADGRB3,NRCAM,ELOVL2,LPIN2,PREX2,EGF
2.253e-03	-6.10	EGF (epidermal growth factor)	protein interactions	1950	28	2	19454	49	ADAM12,EGF
2.253e-03	-6.10	RCOR2 (REST corepressor 2)	protein interactions	283248	28	2	19454	49	PRDM16,CTBP1
2.287e-03	-6.08	NS-malignant_melanoma	COSMIC cancer mutations	NS-malignant_melanoma	3420	19	16828	49	COL11A1,ITPK1,GRK5,PREX2,GPC5,ITPR2,CTNND2,TNS3,DGKB,SNTB1,NCKAP5,LRIG1,ELOVL2,PTPRZ1,SLC39A12,RFX4,SLC13A5,PRDM16,GRIP1
2.362e-03	-6.05	skin-head_neck-carcinoma-squamous_cell_carcinoma	COSMIC cancer mutations	skin-head_neck-carcinoma-squamous_cell_carcinoma	14191	48	16828	49	SLC39A12,NPAS3,SLC13A5,SOX5,NTRK2,SLC4A4,PREX1,FGFRL1,PRDM16,NFIA,ITPR2,GRK5,ITPK1,COL11A1,SNTB1,EGF,TNS3,PTPRZ1,LPIN2,FKBP5,TRPS1,RFX4,ZBTB20,PREX2,DGKB,NCKAP5,QKI,NRCAM,PTN,CTBP1,FHOD3,SLC6A11,LRIG1,ELOVL2,ADAM12,GRIP1,RORA,GPM6B,AQP4,GPC5,SORCS2,USP6NL,APOA1,SLC1A3,CTNND2,SLC1A2,FARP1,NHSL1
2.366e-03	-6.05	amino acid transmembrane transporter activity	molecular function	GO:0015171	100	3	18094	48	SLC1A2,SLC1A3,SLC6A11
2.398e-03	-6.03	amino acid transmembrane transport	biological process	GO:0003333	97	3	18204	50	SLC1A2,SLC1A3,SLC6A11
2.440e-03	-6.02	endometrium-carcinoma-serous_carcinoma	COSMIC cancer mutations	endometrium-carcinoma-serous_carcinoma	1442	11	16828	49	COL11A1,SLC4A4,GPC5,FARP1,CTNND2,DGKB,NCKAP5,EGF,FHOD3,TRPS1,PRDM16
2.448e-03	-6.01	DH_1	prosite domains	PS00741	21	2	12186	43	PREX1,PREX2
2.448e-03	-6.01	DEP	prosite domains	PS50186	21	2	12186	43	PREX2,PREX1
2.519e-03	-5.98	Dynlt1 (dynein light chain Tctex-type 1)	protein interactions	83462	1	1	19454	49	NTRK2
2.519e-03	-5.98	Apob (apolipoprotein B)	protein interactions	238055	1	1	19454	49	APOA1
2.519e-03	-5.98	Syf2 (SYF2 homolog, RNA splicing factor (S. cerevisiae))	protein interactions	68592	1	1	19454	49	GRIP1
2.519e-03	-5.98	E1A (E1A)	protein interactions	2958468	1	1	19454	49	CTBP1
2.519e-03	-5.98	C1QL2 (complement C1q like 2)	protein interactions	165257	1	1	19454	49	ADGRB3
2.519e-03	-5.98	Bdnf (brain derived neurotrophic factor)	protein interactions	12064	1	1	19454	49	NTRK2
2.519e-03	-5.98	ERVK-10 (endogenous retrovirus group K member 10)	protein interactions	100616101	1	1	19454	49	APOA1
2.519e-03	-5.98	SNCA (synuclein alpha)	protein interactions	282857	1	1	19454	49	GRK5
2.519e-03	-5.98	HDAC2 (histone deacetylase 2)	protein interactions	395635	1	1	19454	49	PRDM16
2.519e-03	-5.98	MSB4 (Rab GTPase-activating protein MSB4)	protein interactions	854037	1	1	19454	49	USP6NL
2.536e-03	-5.98	DEP	smart domains	SM00049	21	2	9717	35	PREX2,PREX1
2.550e-03	-5.97	non_small_cell_carcinoma	COSMIC cancer mutations	non_small_cell_carcinoma	5198	25	16828	49	SNTB1,FARP1,CTNND2,SLC1A3,ITPR2,USP6NL,GRK5,RORA,PRDM16,GPM6B,FHOD3,PREX1,ADAM12,LRIG1,QKI,DGKB,NTRK2,PREX2,MSI2,FKBP5,NPAS3,SOX5,TRPS1,PTPRZ1,LPIN2
2.550e-03	-5.97	lung-carcinoma-non_small_cell_carcinoma	COSMIC cancer mutations	lung-carcinoma-non_small_cell_carcinoma	5198	25	16828	49	SOX5,TRPS1,FKBP5,NPAS3,LPIN2,PTPRZ1,QKI,DGKB,PREX2,MSI2,NTRK2,GPM6B,RORA,PRDM16,ADAM12,LRIG1,FHOD3,PREX1,FARP1,CTNND2,SLC1A3,SNTB1,USP6NL,GRK5,ITPR2
2.587e-03	-5.96	regulation of developmental process	biological process	GO:0050793	2540	15	18204	50	EGF,SOX5,PTPRZ1,QKI,RORA,ADGRB3,NRCAM,NTRK2,SLC39A12,PTN,GPM6B,TRPS1,ADAM12,PREX1,GRIP1
2.614e-03	-5.95	regulation of dendrite development	biological process	GO:0050773	100	3	18204	50	PREX1,ADGRB3,PTN
2.653e-03	-5.93	inositol-1,3,4-trisphosphate 6-kinase activity	molecular function	GO:0052725	1	1	18094	48	ITPK1
2.653e-03	-5.93	inositol-3,4,6-trisphosphate 1-kinase activity	molecular function	GO:0052835	1	1	18094	48	ITPK1
2.653e-03	-5.93	brain-derived neurotrophic factor receptor activity	molecular function	GO:0060175	1	1	18094	48	NTRK2
2.653e-03	-5.93	internal N(7)-methylguanine-containing RNA reader activity	molecular function	GO:0160089	1	1	18094	48	QKI
2.653e-03	-5.93	inositol tetrakisphosphate 1-kinase activity	molecular function	GO:0047325	1	1	18094	48	ITPK1
2.653e-03	-5.93	inositol-1,3,4-trisphosphate 5-kinase activity	molecular function	GO:0052726	1	1	18094	48	ITPK1
2.700e-03	-5.91	InsP(3)kin_ATP-grasp	interpro domains	IPR040464	1	1	18521	50	ITPK1
2.700e-03	-5.91	C1_DGKbeta_rpt2	interpro domains	IPR047470	1	1	18521	50	DGKB
2.700e-03	-5.91	Na/ntran_symport_GABA_GAT3	interpro domains	IPR002982	1	1	18521	50	SLC6A11
2.700e-03	-5.91	Rex2_DEP_1	interpro domains	IPR037367	1	1	18521	50	PREX2
2.700e-03	-5.91	PRDM16_PR-SET	interpro domains	IPR044410	1	1	18521	50	PRDM16
2.700e-03	-5.91	NTRK2	interpro domains	IPR020455	1	1	18521	50	NTRK2
2.700e-03	-5.91	C1_DGKbeta-like_rpt1	interpro domains	IPR047471	1	1	18521	50	DGKB
2.700e-03	-5.91	Inositol_tetrakis-P_1-kinase	interpro domains	IPR008656	1	1	18521	50	ITPK1
2.700e-03	-5.91	Quaking_NLS	interpro domains	IPR032367	1	1	18521	50	QKI
2.700e-03	-5.91	TRPS1	interpro domains	IPR028440	1	1	18521	50	TRPS1
2.700e-03	-5.91	ELOVL2	interpro domains	IPR033680	1	1	18521	50	ELOVL2
2.700e-03	-5.91	ITPK1_N	interpro domains	IPR041429	1	1	18521	50	ITPK1
2.700e-03	-5.91	STAR_dimer	interpro domains	IPR032377	1	1	18521	50	QKI
2.700e-03	-5.91	Pro-epidermal_GF	interpro domains	IPR016317	1	1	18521	50	EGF
2.747e-03	-5.90	trans-synaptic signaling by neuropeptide	biological process	GO:0099540	1	1	18204	50	NTRK2
2.747e-03	-5.90	trans-synaptic signaling by neuropeptide, modulating synaptic transmission	biological process	GO:0099551	1	1	18204	50	NTRK2
2.759e-03	-5.89	Effects of PIP2 hydrolysis	REACTOME pathways	R-HSA-114508	27	2	10285	30	DGKB,ITPR2
2.764e-03	-5.89	-	gene3d domains	1.20.5.4010	1	1	14470	40	QKI
2.764e-03	-5.89	-	gene3d domains	3.40.50.11370	1	1	14470	40	ITPK1
2.764e-03	-5.89	-	gene3d domains	1.20.5.20	1	1	14470	40	APOA1
2.764e-03	-5.89	-	gene3d domains	6.10.140.380	1	1	14470	40	APOA1
2.764e-03	-5.89	-	gene3d domains	3.30.1490.220	1	1	14470	40	ITPK1
2.783e-03	-5.88	Transmembrane transport of small molecules	REACTOME pathways	R-HSA-382551	677	7	10285	30	SLC4A4,SLC6A11,SLC1A3,AQP4,APOA1,SLC13A5,SLC1A2
2.810e-03	-5.87	Ins134_P3_kin	pfam domains	PF05770	1	1	17795	50	ITPK1
2.810e-03	-5.87	Ins134_P3_kin_N	pfam domains	PF17927	1	1	17795	50	ITPK1
2.810e-03	-5.87	STAR_dimer	pfam domains	PF16544	1	1	17795	50	QKI
2.810e-03	-5.87	Quaking_NLS	pfam domains	PF16551	1	1	17795	50	QKI
2.823e-03	-5.87	TBR1 (T-box brain transcription factor 1)	protein interactions	10716	112	3	19454	49	SOX5,TRPS1,NFIA
2.843e-03	-5.86	regulation of neural precursor cell proliferation	biological process	GO:2000177	103	3	18204	50	PTN,PTPRZ1,EGF
2.863e-03	-5.86	myoblast fusion	biological process	GO:0007520	29	2	18204	50	ADGRB3,ADAM12
2.866e-03	-5.85	beta-catenin binding	molecular function	GO:0008013	107	3	18094	48	GRIP1,RORA,CTNND2
2.925e-03	-5.83	lymph_node	COSMIC cancer mutations	lymph_node	1703	12	16828	49	SLC1A3,CTNND2,GRK5,COL11A1,SORCS2,ITPK1,NTRK2,ITPR2,GPC5,TRPS1,SOX5,FHOD3
2.945e-03	-5.83	regulation of cell junction assembly	biological process	GO:1901888	217	4	18204	50	GPM6B,FARP1,ADGRB3,NTRK2
2.990e-03	-5.81	tube development	biological process	GO:0035295	903	8	18204	50	QKI,RORA,NFIA,ITPK1,EGF,SLC39A12,NTRK2,NRCAM
3.062e-03	-5.79	L-glutamate import	biological process	GO:0051938	30	2	18204	50	SLC1A3,SLC1A2
3.078e-03	-5.78	Phosphatidylinositol signaling system	KEGG pathways	ko04070	97	3	7161	22	ITPR2,ITPK1,DGKB
3.078e-03	-5.78	Phosphatidylinositol signaling system	KEGG pathways	hsa04070	97	3	7161	22	DGKB,ITPR2,ITPK1
3.089e-03	-5.78	oesophagus-lower_third-carcinoma-squamous_cell_carcinoma	COSMIC cancer mutations	oesophagus-lower_third-carcinoma-squamous_cell_carcinoma	3507	19	16828	49	CTNND2,FARP1,TNS3,NCKAP5,DGKB,COL11A1,SLC4A4,PREX2,GPC5,ZBTB20,NPAS3,SLC13A5,GRIP1,PRDM16,ADAM12,SLC6A11,LRIG1,SLC39A12,PTPRZ1
3.095e-03	-5.78	guanyl-nucleotide exchange factor activity	molecular function	GO:0005085	228	4	18094	48	FARP1,EGF,PREX1,PREX2
3.104e-03	-5.78	upper_aerodigestive_tract	COSMIC cancer mutations	upper_aerodigestive_tract	13181	46	16828	49	CTNND2,SLC1A2,FARP1,NHSL1,SLC1A3,APOA1,USP6NL,SORCS2,GPC5,GPM6B,RORA,ADAM12,ELOVL2,LRIG1,CTBP1,FHOD3,PTN,NRCAM,QKI,NCKAP5,DGKB,MSI2,PREX2,ZBTB20,RFX4,TRPS1,FKBP5,LPIN2,PTPRZ1,TNS3,EGF,SNTB1,ITPK1,COL11A1,GRK5,ITPR2,NFIA,PRDM16,FGFRL1,PREX1,SLC4A4,NTRK2,SOX5,NPAS3,SLC13A5,SLC39A12
3.249e-03	-5.73	bicarbonate transmembrane transporter activity	molecular function	GO:0015106	32	2	18094	48	SLC4A4,SLC39A12
3.252e-03	-5.73	AQUAPORIN4	prints domains	PR02016	1	1	5227	17	AQP4
3.252e-03	-5.73	NTKRECEPTOR2	prints domains	PR01941	1	1	5227	17	NTRK2
3.252e-03	-5.73	GAT3TRNSPORT	prints domains	PR01197	1	1	5227	17	SLC6A11
3.312e-03	-5.71	HGH1 (HGH1 homolog)	protein interactions	51236	34	2	19454	49	FKBP5,PTN
3.312e-03	-5.71	PTPRZ1 (protein tyrosine phosphatase receptor type Z1)	protein interactions	5803	34	2	19454	49	PTN,PTPRZ1
3.349e-03	-5.70	oesophagus-middle_third-carcinoma-squamous_cell_carcinoma	COSMIC cancer mutations	oesophagus-middle_third-carcinoma-squamous_cell_carcinoma	3531	19	16828	49	FHOD3,SLC39A12,PTPRZ1,LRIG1,FKBP5,PRDM16,SOX5,GPC5,ZBTB20,ITPK1,SORCS2,SLC4A4,COL11A1,PREX2,GRK5,CTNND2,NHSL1,FARP1,TNS3
3.371e-03	-5.69	middle_third	COSMIC cancer mutations	middle_third	3533	19	16828	49	ZBTB20,GPC5,GRK5,PREX2,SORCS2,ITPK1,COL11A1,SLC4A4,TNS3,CTNND2,FARP1,NHSL1,SLC39A12,PTPRZ1,FHOD3,LRIG1,PRDM16,FKBP5,SOX5
3.404e-03	-5.68	cellular response to endogenous stimulus	biological process	GO:0071495	1135	9	18204	50	LPIN2,NTRK2,APOA1,SLC1A3,ITPR2,NFIA,FGFRL1,SOX5,SLC1A2
3.434e-03	-5.67	Transmission across Chemical Synapses	REACTOME pathways	R-HSA-112315	217	4	10285	30	SLC6A11,SLC1A3,GRIP1,SLC1A2
3.472e-03	-5.66	monoatomic ion transmembrane transporter activity	molecular function	GO:0015075	752	7	18094	48	SLC6A11,SLC1A2,SLC1A3,ITPR2,SLC39A12,SLC4A4,SLC13A5
3.479e-03	-5.66	transepithelial transport	biological process	GO:0070633	32	2	18204	50	SLC1A2,SLC1A3
3.479e-03	-5.66	positive regulation of ATP metabolic process	biological process	GO:1903580	32	2	18204	50	ZBTB20,SLC4A4
3.531e-03	-5.65	central_nervous_system-cerebellum-glioma-astrocytoma_Grade_I	COSMIC cancer mutations	central_nervous_system-cerebellum-glioma-astrocytoma_Grade_I	105	3	16828	49	PRDM16,GPC5,QKI
3.588e-03	-5.63	nodular	COSMIC cancer mutations	nodular	1515	11	16828	49	EGF,CTNND2,NTRK2,SLC4A4,COL11A1,PREX2,GRK5,NPAS3,FKBP5,PTPRZ1,SLC6A11
3.601e-03	-5.63	regulation of gliogenesis	biological process	GO:0014013	112	3	18204	50	PTN,QKI,PTPRZ1
3.624e-03	-5.62	Transport of inorganic cations/anions and amino acids/oligopeptides	REACTOME pathways	R-HSA-425393	107	3	10285	30	SLC1A2,SLC1A3,SLC4A4
3.652e-03	-5.61	circulatory system development	biological process	GO:0072359	933	8	18204	50	COL11A1,EGF,FHOD3,NRCAM,NTRK2,QKI,RORA,FGFRL1
3.688e-03	-5.60	CRX (cone-rod homeobox)	protein interactions	1406	252	4	19454	49	NFIA,PRDM16,SOX5,TRPS1
3.697e-03	-5.60	response to auditory stimulus	biological process	GO:0010996	33	2	18204	50	PTN,SLC1A3
3.707e-03	-5.60	PTPRB (protein tyrosine phosphatase receptor type B)	protein interactions	5787	36	2	19454	49	PTN,NRCAM
3.758e-03	-5.58	plasma membrane bounded cell projection organization	biological process	GO:0120036	1152	9	18204	50	CTNND2,PREX2,GPM6B,PTN,RFX4,PTPRZ1,NRCAM,SLC39A12,FARP1
3.912e-03	-5.54	Ig_sub2	interpro domains	IPR003598	239	4	18521	50	FGFRL1,NRCAM,LRIG1,NTRK2
3.913e-03	-5.54	TRNAU1AP (tRNA selenocysteine 1 associated protein 1)	protein interactions	54952	37	2	19454	49	QKI,ZBTB20
3.979e-03	-5.53	glutamatergic synapse	cellular component	GO:0098978	412	5	19108	49	SLC1A2,FARP1,CTBP1,ADGRB3,NRCAM
4.021e-03	-5.52	PAX9 (paired box 9)	protein interactions	5083	127	3	19454	49	NFIA,TRPS1,QKI
4.043e-03	-5.51	postsynaptic specialization membrane	cellular component	GO:0099634	125	3	19108	49	NRCAM,ADGRB3,SORCS2
4.052e-03	-5.51	glial cell projection	cellular component	GO:0097386	37	2	19108	49	SLC1A2,AQP4
4.071e-03	-5.50	regulation of synapse assembly	biological process	GO:0051963	117	3	18204	50	NTRK2,ADGRB3,FARP1
4.094e-03	-5.50	transporter activity	molecular function	GO:0005215	1211	9	18094	48	SLC6A11,AQP4,SLC1A2,SLC1A3,SLC39A12,ITPR2,SLC4A4,APOA1,SLC13A5
4.151e-03	-5.48	astrocytoma_Grade_III	COSMIC cancer mutations	astrocytoma_Grade_III	1544	11	16828	49	COL11A1,GRK5,FHOD3,GPC5,SLC39A12,FARP1,TNS3,GRIP1,PRDM16,SNTB1,NCKAP5
4.157e-03	-5.48	organic substance transport	biological process	GO:0071702	1881	12	18204	50	SLC13A5,SLC1A3,SLC39A12,SORCS2,NTRK2,GPM6B,GRIP1,SLC6A11,APOA1,SLC4A4,QKI,SLC1A2
4.201e-03	-5.47	CHD7 (chromodomain helicase DNA binding protein 7)	protein interactions	55636	129	3	19454	49	ZBTB20,FKBP5,SOX5
4.356e-03	-5.44	mesothelioma	COSMIC cancer mutations	mesothelioma	4477	22	16828	49	ADAM12,LPIN2,LRIG1,PTPRZ1,PREX1,GPM6B,SOX5,TRPS1,FKBP5,RORA,PRDM16,USP6NL,MSI2,GRK5,PREX2,ITPR2,NTRK2,CTNND2,FARP1,QKI,DGKB,SNTB1
4.386e-03	-5.43	TRPS1 (transcriptional repressor GATA binding 1)	protein interactions	7227	131	3	19454	49	SOX5,NFIA,CTBP1
4.388e-03	-5.43	syncytium formation by plasma membrane fusion	biological process	GO:0000768	36	2	18204	50	ADGRB3,ADAM12
4.388e-03	-5.43	cell-cell fusion	biological process	GO:0140253	36	2	18204	50	ADAM12,ADGRB3
4.432e-03	-5.42	D-myo-inositol (3,4,5,6)-tetrakisphosphate biosynthesis	BIOCYC pathways	HUMAN_PWY-6365	2	1	902	2	ITPK1
4.432e-03	-5.42	D-myo-inositol (3,4,5,6)-tetrakisphosphate biosynthesis	BIOCYC pathways	META_PWY-6365	2	1	902	2	ITPK1
4.448e-03	-5.42	central_nervous_system-brainstem-glioma-oligoastrocytoma_Grade_III	COSMIC cancer mutations	central_nervous_system-brainstem-glioma-oligoastrocytoma_Grade_III	114	3	16828	49	SLC1A2,SOX5,PREX2
4.451e-03	-5.41	anatomical structure formation involved in morphogenesis	biological process	GO:0048646	964	8	18204	50	RORA,ADGRB3,ADAM12,COL11A1,SLC39A12,EGF,FHOD3,NRCAM
4.480e-03	-5.41	DCAF11 (DDB1 and CUL4 associated factor 11)	protein interactions	80344	132	3	19454	49	CTBP1,GRIP1,LPIN2
4.605e-03	-5.38	regulation of synapse organization	biological process	GO:0050807	246	4	18204	50	NRCAM,NTRK2,ADGRB3,FARP1
4.605e-03	-5.38	positive regulation of neurogenesis	biological process	GO:0050769	246	4	18204	50	NTRK2,PTPRZ1,QKI,PTN
4.607e-03	-5.38	urinary_tract-bladder-carcinoma-transitional_cell_carcinoma	COSMIC cancer mutations	urinary_tract-bladder-carcinoma-transitional_cell_carcinoma	6040	27	16828	49	LPIN2,PTPRZ1,TRPS1,RFX4,FKBP5,PREX2,SLC4A4,ZBTB20,NTRK2,NRCAM,SLC6A11,ELOVL2,LRIG1,ADAM12,PREX1,FGFRL1,NFIA,PRDM16,GRIP1,GRK5,COL11A1,ITPR2,GPC5,TNS3,SLC1A3,FARP1,EGF
4.631e-03	-5.38	positive regulation of purine nucleotide metabolic process	biological process	GO:1900544	37	2	18204	50	ZBTB20,SLC4A4
4.631e-03	-5.38	positive regulation of nucleotide metabolic process	biological process	GO:0045981	37	2	18204	50	ZBTB20,SLC4A4
4.631e-03	-5.38	bicarbonate transport	biological process	GO:0015701	37	2	18204	50	SLC39A12,SLC4A4
4.631e-03	-5.37	transitional_cell_carcinoma	COSMIC cancer mutations	transitional_cell_carcinoma	6042	27	16828	49	FKBP5,RFX4,TRPS1,PTPRZ1,LPIN2,NRCAM,ZBTB20,NTRK2,SLC4A4,PREX2,GRIP1,PRDM16,NFIA,FGFRL1,PREX1,ADAM12,SLC6A11,ELOVL2,LRIG1,EGF,FARP1,TNS3,SLC1A3,GPC5,ITPR2,COL11A1,GRK5
4.648e-03	-5.37	positive regulation of cellular process	biological process	GO:0048522	5719	25	18204	50	PRDM16,CTBP1,GPC5,SLC1A3,PTN,RFX4,ZBTB20,QKI,ADGRB3,SLC1A2,NTRK2,NRCAM,NFIA,PREX1,GRK5,GRIP1,FARP1,LPIN2,SLC4A4,EGF,APOA1,NPAS3,SOX5,PTPRZ1,RORA
4.649e-03	-5.37	RND3 (Rho family GTPase 3)	protein interactions	390	269	4	19454	49	CTBP1,FARP1,SNTB1,USP6NL
4.672e-03	-5.37	AKT2 (AKT serine/threonine kinase 2)	protein interactions	208	134	3	19454	49	GRK5,FKBP5,APOA1
4.697e-03	-5.36	Sudden Infant Death Syndrome (SIDS) Susceptibility Pathways	WikiPathways	WP706	162	4	5310	23	NTRK2,SLC1A3,RORA,AQP4
4.710e-03	-5.36	WDR6 (WD repeat domain 6)	protein interactions	11180	270	4	19454	49	FKBP5,NTRK2,GRIP1,FARP1
4.770e-03	-5.35	FOXP1 (forkhead box P1)	protein interactions	27086	135	3	19454	49	SOX5,NFIA,CTBP1
4.788e-03	-5.34	fat cell differentiation	biological process	GO:0045444	124	3	18204	50	GRK5,CTBP1,PRDM16
4.834e-03	-5.33	enzyme activator activity	molecular function	GO:0008047	599	6	18094	48	EGF,ADGRB3,USP6NL,PREX1,PREX2,APOA1
4.853e-03	-5.33	Glutamatergic synapse	KEGG pathways	ko04724	114	3	7161	22	ITPR2,SLC1A2,SLC1A3
4.853e-03	-5.33	Glutamatergic synapse	KEGG pathways	hsa04724	114	3	7161	22	SLC1A2,ITPR2,SLC1A3
4.858e-03	-5.33	humerus	COSMIC cancer mutations	humerus	546	6	16828	49	FARP1,SOX5,EGF,NCKAP5,FHOD3,GPC5
4.868e-03	-5.33	dendrite	cellular component	GO:0030425	620	6	19108	49	SORCS2,FARP1,GRIP1,NTRK2,PREX1,CTNND2
4.872e-03	-5.32	EGFR interacts with phospholipase C-gamma	REACTOME pathways	R-HSA-212718	36	2	10285	30	ITPR2,EGF
4.873e-03	-5.32	PDZ	pfam domains	PF00595	122	3	17795	50	GRIP1,PREX2,SNTB1
4.880e-03	-5.32	amino acid import across plasma membrane	biological process	GO:0089718	38	2	18204	50	SLC1A3,SLC1A2
4.915e-03	-5.32	cell projection organization	biological process	GO:0030030	1200	9	18204	50	SLC39A12,NRCAM,FARP1,CTNND2,RFX4,PTPRZ1,GPM6B,PREX2,PTN
4.944e-03	-5.31	dendritic tree	cellular component	GO:0097447	622	6	19108	49	PREX1,SORCS2,CTNND2,FARP1,GRIP1,NTRK2
4.969e-03	-5.30	TBL1X (transducin beta like 1 X-linked)	protein interactions	6907	137	3	19454	49	CTBP1,NFIA,SOX5
4.977e-03	-5.30	striated_muscle	COSMIC cancer mutations	striated_muscle	4228	21	16828	49	ELOVL2,CTBP1,FGFRL1,FHOD3,PTPRZ1,AQP4,NFIA,TRPS1,NPAS3,RORA,PRDM16,USP6NL,SORCS2,PREX2,GRK5,CTNND2,NHSL1,SLC1A3,EGF,NCKAP5,DGKB
5.014e-03	-5.30	regulation of synapse structure or activity	biological process	GO:0050803	252	4	18204	50	NTRK2,ADGRB3,NRCAM,FARP1
5.031e-03	-5.29	Fkbp3 (FK506 binding protein 3)	protein interactions	30795	2	1	19454	49	CTBP1
5.031e-03	-5.29	MSB3 (Rab GTPase-activating protein MSB3)	protein interactions	855423	2	1	19454	49	USP6NL
5.031e-03	-5.29	BTBD17 (BTB domain containing 17)	protein interactions	388419	2	1	19454	49	PRDM16
5.134e-03	-5.27	syncytium formation	biological process	GO:0006949	39	2	18204	50	ADAM12,ADGRB3
5.134e-03	-5.27	cellular response to alkaloid	biological process	GO:0071312	39	2	18204	50	SLC1A3,SLC1A2
5.231e-03	-5.25	myelination	biological process	GO:0042552	128	3	18204	50	NTRK2,QKI,GPM6B
5.254e-03	-5.25	SDC3 (syndecan 3)	protein interactions	9672	43	2	19454	49	PTN,FARP1
5.299e-03	-5.24	inositol tetrakisphosphate 6-kinase activity	molecular function	GO:0000825	2	1	18094	48	ITPK1
5.377e-03	-5.23	somatodendritic compartment	cellular component	GO:0036477	842	7	19108	49	SORCS2,CTNND2,FARP1,PREX1,NTRK2,GRIP1,SLC1A3
5.382e-03	-5.22	SNTB2 (syntrophin beta 2)	protein interactions	6645	141	3	19454	49	SNTB1,GRIP1,TNS3
5.392e-03	-5.22	GRIP1/2	interpro domains	IPR043545	2	1	18521	50	GRIP1
5.392e-03	-5.22	Midkine_heparin-bd_GF	interpro domains	IPR000762	2	1	18521	50	PTN
5.392e-03	-5.22	CtBP	interpro domains	IPR043322	2	1	18521	50	CTBP1
5.392e-03	-5.22	MSI_RRM2	interpro domains	IPR034126	2	1	18521	50	MSI2
5.392e-03	-5.22	ZIP4_12_EF-hand	interpro domains	IPR049406	2	1	18521	50	SLC39A12
5.392e-03	-5.22	NCKAP5_C	interpro domains	IPR032769	2	1	18521	50	NCKAP5
5.392e-03	-5.22	ZIP4_N	interpro domains	IPR041137	2	1	18521	50	SLC39A12
5.392e-03	-5.22	PTN/MK_diS_sf	interpro domains	IPR020091	2	1	18521	50	PTN
5.392e-03	-5.22	Alpha_CARP_receptor-type	interpro domains	IPR041887	2	1	18521	50	PTPRZ1
5.392e-03	-5.22	PTN/MK_C_dom	interpro domains	IPR020090	2	1	18521	50	PTN
5.392e-03	-5.22	Nckap5l	interpro domains	IPR026163	2	1	18521	50	NCKAP5
5.392e-03	-5.22	PTN_MK_heparin-bd_GF_CS	interpro domains	IPR020092	2	1	18521	50	PTN
5.392e-03	-5.22	FHOD1_GBD_N	interpro domains	IPR041387	2	1	18521	50	FHOD3
5.392e-03	-5.22	PTN/MK_C_dom_sf	interpro domains	IPR038130	2	1	18521	50	PTN
5.392e-03	-5.22	PTN/MK_N_dom	interpro domains	IPR020089	2	1	18521	50	PTN
5.392e-03	-5.22	PTN/MK_N_dom_sf	interpro domains	IPR037122	2	1	18521	50	PTN
5.461e-03	-5.21	ensheathment of neurons	biological process	GO:0007272	130	3	18204	50	NTRK2,GPM6B,QKI
5.461e-03	-5.21	axon ensheathment	biological process	GO:0008366	130	3	18204	50	QKI,GPM6B,NTRK2
5.486e-03	-5.21	fumarate transport	biological process	GO:0015741	2	1	18204	50	SLC13A5
5.486e-03	-5.21	tricarboxylic acid transmembrane transport	biological process	GO:0035674	2	1	18204	50	SLC13A5
5.486e-03	-5.21	negative regulation of 3'-UTR-mediated mRNA stabilization	biological process	GO:1905869	2	1	18204	50	QKI
5.486e-03	-5.21	retrograde transport, plasma membrane to Golgi	biological process	GO:0035526	2	1	18204	50	USP6NL
5.486e-03	-5.21	dendrite regeneration	biological process	GO:0031104	2	1	18204	50	PTN
5.486e-03	-5.21	retrograde trans-synaptic signaling by trans-synaptic protein complex	biological process	GO:0098942	2	1	18204	50	FARP1
5.486e-03	-5.21	myofibroblast contraction	biological process	GO:1990764	2	1	18204	50	QKI
5.521e-03	-5.20	Pleiotrophin/Midkine, N-terminal domain	gene3d domains	2.20.60.10	2	1	14470	40	PTN
5.521e-03	-5.20	-	gene3d domains	6.10.250.2260	2	1	14470	40	GRK5
5.545e-03	-5.19	neutral L-amino acid transmembrane transporter activity	molecular function	GO:0015175	42	2	18094	48	SLC1A3,SLC1A2
5.578e-03	-5.19	carboxylic acid transmembrane transport	biological process	GO:1905039	131	3	18204	50	SLC1A3,SLC1A2,SLC13A5
5.612e-03	-5.18	PTN_MK_C	pfam domains	PF01091	2	1	17795	50	PTN
5.612e-03	-5.18	NCKAP5	pfam domains	PF15246	2	1	17795	50	NCKAP5
5.612e-03	-5.18	EF-hand_Zip	pfam domains	PF21116	2	1	17795	50	SLC39A12
5.612e-03	-5.18	Formin_GBD_N	pfam domains	PF18382	2	1	17795	50	FHOD3
5.612e-03	-5.18	PTN_MK_N	pfam domains	PF05196	2	1	17795	50	PTN
5.612e-03	-5.18	ZIP4_domain	pfam domains	PF18292	2	1	17795	50	SLC39A12
5.621e-03	-5.18	skin-ear-malignant_melanoma	COSMIC cancer mutations	skin-ear-malignant_melanoma	124	3	16828	49	FGFRL1,SLC6A11,GRK5
5.706e-03	-5.17	PH_domain	interpro domains	IPR001849	266	4	18521	50	PREX1,PREX2,FARP1,SNTB1
5.755e-03	-5.16	kidney-carcinoma-clear_cell_renal_cell_carcinoma	COSMIC cancer mutations	kidney-carcinoma-clear_cell_renal_cell_carcinoma	13924	47	16828	49	NTRK2,SLC4A4,SLC39A12,NPAS3,SLC13A5,SOX5,ITPR2,GRK5,ITPK1,COL11A1,SNTB1,EGF,TNS3,PREX1,FGFRL1,PRDM16,NFIA,ZBTB20,MSI2,PREX2,NCKAP5,DGKB,QKI,NRCAM,PTN,PTPRZ1,LPIN2,FKBP5,TRPS1,GPC5,USP6NL,SORCS2,SLC1A3,CTNND2,FARP1,SLC1A2,NHSL1,CTBP1,FHOD3,SLC6A11,LRIG1,ELOVL2,ADAM12,GRIP1,RORA,GPM6B,AQP4
5.755e-03	-5.16	clear_cell_renal_cell_carcinoma	COSMIC cancer mutations	clear_cell_renal_cell_carcinoma	13924	47	16828	49	FGFRL1,PREX1,NFIA,PRDM16,ITPK1,COL11A1,GRK5,ITPR2,TNS3,EGF,SNTB1,SLC39A12,SOX5,NPAS3,SLC13A5,SLC4A4,NTRK2,ADAM12,SLC6A11,LRIG1,ELOVL2,CTBP1,FHOD3,GPM6B,AQP4,RORA,GRIP1,SORCS2,USP6NL,GPC5,CTNND2,SLC1A2,FARP1,NHSL1,SLC1A3,LPIN2,PTPRZ1,TRPS1,FKBP5,MSI2,PREX2,ZBTB20,PTN,NRCAM,QKI,DGKB,NCKAP5
5.755e-03	-5.16	SOX2 (SRY-box transcription factor 2)	protein interactions	6657	1342	9	19454	49	NFIA,APOA1,QKI,MSI2,TRPS1,ITPR2,CTBP1,COL11A1,SOX5
5.826e-03	-5.15	Signaling by Overexpressed Wild-Type EGFR in Cancer	REACTOME pathways	R-HSA-5638302	2	1	10285	30	EGF
5.826e-03	-5.15	Inhibition of Signaling by Overexpressed EGFR	REACTOME pathways	R-HSA-5638303	2	1	10285	30	EGF
5.859e-03	-5.14	GTPase activator activity	molecular function	GO:0005096	273	4	18094	48	ADGRB3,PREX2,USP6NL,PREX1
5.924e-03	-5.13	Fatty acid, triacylglycerol, and ketone body metabolism	REACTOME pathways	R-HSA-535734	253	4	10285	30	ELOVL2,APOA1,RORA,LPIN2
5.935e-03	-5.13	regulation of protein localization to cell surface	biological process	GO:2000008	42	2	18204	50	GPM6B,EGF
5.935e-03	-5.13	neuron maturation	biological process	GO:0042551	42	2	18204	50	NRCAM,ADGRB3
5.935e-03	-5.13	triglyceride homeostasis	biological process	GO:0070328	42	2	18204	50	APOA1,RORA
5.978e-03	-5.12	PH-like_dom_sf	interpro domains	IPR011993	431	5	18521	50	PREX1,PREX2,FARP1,TNS3,SNTB1
5.994e-03	-5.12	TRIM47 (tripartite motif containing 47)	protein interactions	91107	46	2	19454	49	TNS3,CTNND2
6.041e-03	-5.11	TFAP4 (transcription factor AP-4)	protein interactions	7023	147	3	19454	49	PRDM16,CTBP1,NFIA
6.087e-03	-5.10	regulation of cellular component biogenesis	biological process	GO:0044087	1016	8	18204	50	FARP1,NTRK2,SLC39A12,APOA1,GPM6B,ADGRB3,PREX1,USP6NL
6.090e-03	-5.10	monoatomic ion transmembrane transport	biological process	GO:0034220	804	7	18204	50	SLC6A11,ITPR2,SLC1A3,SLC39A12,SLC13A5,SLC4A4,SLC1A2
6.126e-03	-5.10	neuron projection	cellular component	GO:0043005	1331	9	19108	49	NRCAM,PREX1,CTNND2,GRIP1,SLC1A3,NTRK2,SLC1A2,SORCS2,FARP1
6.155e-03	-5.09	ATXN1L (ataxin 1 like)	protein interactions	342371	148	3	19454	49	SOX5,CTBP1,NFIA
6.213e-03	-5.08	acylglycerol homeostasis	biological process	GO:0055090	43	2	18204	50	APOA1,RORA
6.213e-03	-5.08	positive regulation of substrate adhesion-dependent cell spreading	biological process	GO:1900026	43	2	18204	50	APOA1,PREX1
6.276e-03	-5.07	oesophagus-carcinoma-squamous_cell_carcinoma	COSMIC cancer mutations	oesophagus-carcinoma-squamous_cell_carcinoma	6486	28	16828	49	FKBP5,NPAS3,TRPS1,SOX5,PTPRZ1,SLC39A12,LPIN2,NCKAP5,DGKB,ZBTB20,PREX2,SLC4A4,GRIP1,PRDM16,AQP4,FGFRL1,ADAM12,SNTB1,EGF,APOA1,TNS3,FARP1,CTNND2,ITPR2,GPC5,COL11A1,ITPK1,SORCS2
6.324e-03	-5.06	monoatomic anion transmembrane transporter activity	molecular function	GO:0008509	142	3	18094	48	SLC6A11,SLC4A4,SLC1A2
6.372e-03	-5.06	haematopoietic_and_lymphoid_tissue-haematopoietic_neoplasm-acute_myeloid_leukaemia	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue-haematopoietic_neoplasm-acute_myeloid_leukaemia	10418	39	16828	49	SLC39A12,PTPRZ1,LPIN2,NPAS3,FKBP5,SLC13A5,SOX5,RFX4,NTRK2,MSI2,PREX2,SLC4A4,DGKB,NCKAP5,QKI,PREX1,FHOD3,SLC6A11,LRIG1,ELOVL2,ADAM12,GRIP1,PRDM16,RORA,NFIA,ITPR2,GPC5,GRK5,USP6NL,ITPK1,SORCS2,COL11A1,EGF,TNS3,SLC1A3,CTNND2,FARP1,NHSL1,SLC1A2
6.372e-03	-5.06	acute_myeloid_leukaemia	COSMIC cancer mutations	acute_myeloid_leukaemia	10418	39	16828	49	SLC39A12,PTPRZ1,LPIN2,NPAS3,SLC13A5,FKBP5,SOX5,RFX4,NTRK2,MSI2,PREX2,SLC4A4,NCKAP5,DGKB,QKI,PREX1,FHOD3,SLC6A11,ELOVL2,LRIG1,ADAM12,PRDM16,GRIP1,RORA,NFIA,ITPR2,GPC5,GRK5,USP6NL,ITPK1,SORCS2,COL11A1,EGF,TNS3,SLC1A3,CTNND2,NHSL1,FARP1,SLC1A2
6.387e-03	-5.05	KDM2B (lysine demethylase 2B)	protein interactions	84678	150	3	19454	49	NFIA,CTBP1,SOX5
6.388e-03	-5.05	Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)	gene3d domains	2.30.29.30	431	5	14470	40	SNTB1,FARP1,PREX1,PREX2,TNS3
6.402e-03	-5.05	skin-extremity-malignant_melanoma	COSMIC cancer mutations	skin-extremity-malignant_melanoma	1875	12	16828	49	PTPRZ1,FHOD3,CTBP1,SLC6A11,ADAM12,PRDM16,FKBP5,NTRK2,PREX2,USP6NL,SORCS2,APOA1
6.420e-03	-5.05	response to wounding	biological process	GO:0009611	431	5	18204	50	ITPK1,NFIA,DGKB,SLC1A3,SLC1A2
6.429e-03	-5.05	extremity	COSMIC cancer mutations	extremity	1876	12	16828	49	ADAM12,SLC6A11,CTBP1,FHOD3,PTPRZ1,FKBP5,PRDM16,SORCS2,USP6NL,PREX2,NTRK2,APOA1
6.441e-03	-5.04	sodium ion transmembrane transport	biological process	GO:0035725	138	3	18204	50	SLC4A4,SLC13A5,SLC6A11
6.441e-03	-5.04	regulation of generation of precursor metabolites and energy	biological process	GO:0043467	138	3	18204	50	ZBTB20,SLC4A4,PRDM16
6.495e-03	-5.04	PTNMIDKINE	prints domains	PR00269	2	1	5227	17	PTN
6.498e-03	-5.04	positive regulation of bone mineralization	biological process	GO:0030501	44	2	18204	50	PTN,GPM6B
6.576e-03	-5.02	SP7 (Sp7 transcription factor)	protein interactions	121340	297	4	19454	49	QKI,SOX5,TRPS1,NFIA
6.645e-03	-5.01	1D-myo-inositol hexakisphosphate biosynthesis V (from Ins(1,3,4)P3)	BIOCYC pathways	HUMAN_PWY-6554	3	1	902	2	ITPK1
6.645e-03	-5.01	D-myo-inositol (1,4,5,6)-tetrakisphosphate biosynthesis	BIOCYC pathways	META_PWY-6366	3	1	902	2	ITPK1
6.645e-03	-5.01	docosahexaenoate biosynthesis IV (4-desaturase, mammals)	BIOCYC pathways	META_PWY-7727	3	1	902	2	ELOVL2
6.645e-03	-5.01	D-myo-inositol (1,4,5,6)-tetrakisphosphate biosynthesis	BIOCYC pathways	HUMAN_PWY-6366	3	1	902	2	ITPK1
6.645e-03	-5.01	(4Z,7Z,10Z,13Z,16Z)-docosa-4,7,10,13,16-pentaenoate biosynthesis II (4-desaturase)	BIOCYC pathways	META_PWY-7728	3	1	902	2	ELOVL2
6.645e-03	-5.01	docosahexaenoate biosynthesis III (mammals)	BIOCYC pathways	HUMAN_PWY-7606	3	1	902	2	ELOVL2
6.670e-03	-5.01	blood vessel morphogenesis	biological process	GO:0048514	435	5	18204	50	QKI,RORA,NRCAM,NTRK2,EGF
6.676e-03	-5.01	inorganic cation transmembrane transport	biological process	GO:0098662	618	6	18204	50	SLC6A11,SLC4A4,SLC39A12,SLC1A3,ITPR2,SLC13A5
6.702e-03	-5.01	neurotransmitter transport	biological process	GO:0006836	140	3	18204	50	SLC6A11,SLC1A2,SLC1A3
6.833e-03	-4.99	perikaryon	cellular component	GO:0043204	151	3	19108	49	GRIP1,CTNND2,SORCS2
6.890e-03	-4.98	learning or memory	biological process	GO:0007611	276	4	18204	50	PTPRZ1,PTN,ADGRB3,NTRK2
6.904e-03	-4.98	transcription corepressor binding	molecular function	GO:0001222	47	2	18094	48	CTBP1,RORA
6.969e-03	-4.97	monoatomic anion transmembrane transport	biological process	GO:0098656	142	3	18204	50	SLC4A4,SLC1A2,SLC1A3
6.969e-03	-4.97	positive regulation of small molecule metabolic process	biological process	GO:0062013	142	3	18204	50	SLC4A4,APOA1,ZBTB20
7.045e-03	-4.96	D_2_HYDROXYACID_DH_1	prosite domains	PS00065	2	1	12186	43	CTBP1
7.045e-03	-4.96	PTN_MK_1	prosite domains	PS00619	2	1	12186	43	PTN
7.045e-03	-4.96	PTN_MK_2	prosite domains	PS00620	2	1	12186	43	PTN
7.049e-03	-4.95	ZNF516 (zinc finger protein 516)	protein interactions	9658	50	2	19454	49	CTBP1,PRDM16
7.065e-03	-4.95	regulation of GTPase activity	biological process	GO:0043087	278	4	18204	50	PREX2,USP6NL,PREX1,NTRK2
7.084e-03	-4.95	regulation of myelination	biological process	GO:0031641	46	2	18204	50	PTPRZ1,PTN
7.096e-03	-4.95	NRAS (NRAS proto-oncogene, GTPase)	protein interactions	4893	683	6	19454	49	SLC39A12,USP6NL,FGFRL1,PREX1,FARP1,SLC1A3
7.119e-03	-4.94	oligoastrocytoma_Grade_III	COSMIC cancer mutations	oligoastrocytoma_Grade_III	263	4	16828	49	PREX2,SOX5,SLC1A2,GRIP1
7.191e-03	-4.93	PTN	smart domains	SM00193	2	1	9717	35	PTN
7.211e-03	-4.93	Retinoid metabolism and transport	REACTOME pathways	R-HSA-975634	44	2	10285	30	GPC5,APOA1
7.213e-03	-4.93	system process	biological process	GO:0003008	2015	12	18204	50	SLC1A3,NRCAM,NTRK2,COL11A1,PTN,SLC4A4,SNTB1,AQP4,SLC1A2,ADGRB3,LRIG1,PTPRZ1
7.272e-03	-4.92	Ig_3	pfam domains	PF13927	141	3	17795	50	NRCAM,FGFRL1,LRIG1
7.312e-03	-4.92	metal ion transport	biological process	GO:0030001	630	6	18204	50	SLC6A11,SLC39A12,SLC1A3,ITPR2,SLC13A5,SLC4A4
7.400e-03	-4.91	skin-face-malignant_melanoma	COSMIC cancer mutations	skin-face-malignant_melanoma	137	3	16828	49	PREX2,SLC6A11,ADAM12
7.496e-03	-4.89	ITGAV (integrin subunit alpha V)	protein interactions	3685	159	3	19454	49	PTN,COL11A1,PTPRZ1
7.538e-03	-4.89	SMPDL3A (sphingomyelin phosphodiesterase acid like 3A)	protein interactions	10924	3	1	19454	49	APOA1
7.538e-03	-4.89	IL34 (interleukin 34)	protein interactions	146433	3	1	19454	49	PTPRZ1
7.538e-03	-4.89	Lep (leptin)	protein interactions	16846	3	1	19454	49	APOA1
7.538e-03	-4.89	Eif1b (eukaryotic translation initiation factor 1B)	protein interactions	68969	3	1	19454	49	GRIP1
7.538e-03	-4.89	APOL1 (apolipoprotein L1)	protein interactions	8542	3	1	19454	49	APOA1
7.538e-03	-4.89	E1A (control protein E1A;control protein E1A 243R)	protein interactions	2652980	3	1	19454	49	CTBP1
7.538e-03	-4.89	cbx2.L (chromobox 2 L homeolog)	protein interactions	398110	3	1	19454	49	CTBP1
7.538e-03	-4.89	FAM83C (family with sequence similarity 83 member C)	protein interactions	128876	3	1	19454	49	APOA1
7.605e-03	-4.88	ABCA1 (ATP binding cassette subfamily A member 1)	protein interactions	19	52	2	19454	49	SNTB1,APOA1
7.626e-03	-4.88	NEK6 (NIMA related kinase 6)	protein interactions	10783	160	3	19454	49	PTN,GRIP1,PRDM16
7.626e-03	-4.88	SOX5 (SRY-box transcription factor 5)	protein interactions	6660	160	3	19454	49	NFIA,SOX5,TRPS1
7.631e-03	-4.88	human chr8q23.3	chromosome location	human chr8q23.3	4	1	26134	50	TRPS1
7.646e-03	-4.87	monoatomic cation transmembrane transport	biological process	GO:0098655	636	6	18204	50	SLC6A11,SLC13A5,SLC39A12,ITPR2,SLC1A3,SLC4A4
7.700e-03	-4.87	astrocytoma_Grade_I	COSMIC cancer mutations	astrocytoma_Grade_I	139	3	16828	49	PRDM16,QKI,GPC5
7.700e-03	-4.87	skin-lower_leg-malignant_melanoma	COSMIC cancer mutations	skin-lower_leg-malignant_melanoma	139	3	16828	49	ADAM12,SLC6A11,PREX2
7.938e-03	-4.84	inositol 1,4,5-trisphosphate-gated calcium channel activity	molecular function	GO:0005220	3	1	18094	48	ITPR2
7.938e-03	-4.84	high-density lipoprotein particle receptor binding	molecular function	GO:0070653	3	1	18094	48	APOA1
7.938e-03	-4.84	cysteine transmembrane transporter activity	molecular function	GO:0033229	3	1	18094	48	SLC1A2
7.938e-03	-4.84	taurine:sodium symporter activity	molecular function	GO:0005369	3	1	18094	48	SLC6A11
7.938e-03	-4.84	sodium:dicarboxylate symporter activity	molecular function	GO:0017153	3	1	18094	48	SLC13A5
8.078e-03	-4.82	Na/sul_symport_CS	interpro domains	IPR031312	3	1	18521	50	SLC13A5
8.078e-03	-4.82	ROR_rcpt	interpro domains	IPR003079	3	1	18521	50	RORA
8.078e-03	-4.82	LIPIN	interpro domains	IPR026058	3	1	18521	50	LPIN2
8.078e-03	-4.82	Lipin_mid	interpro domains	IPR031703	3	1	18521	50	LPIN2
8.078e-03	-4.82	Lipin_N	interpro domains	IPR007651	3	1	18521	50	LPIN2
8.078e-03	-4.82	LNS2	interpro domains	IPR013209	3	1	18521	50	LPIN2
8.078e-03	-4.82	Myelin_PLP_CS	interpro domains	IPR018237	3	1	18521	50	GPM6B
8.078e-03	-4.82	NTRK_LRRCT	interpro domains	IPR031635	3	1	18521	50	NTRK2
8.078e-03	-4.82	D-isomer_DH_CS1	interpro domains	IPR029752	3	1	18521	50	CTBP1
8.078e-03	-4.82	NTRK	interpro domains	IPR020777	3	1	18521	50	NTRK2
8.078e-03	-4.82	AGRB_N	interpro domains	IPR043838	3	1	18521	50	ADGRB3
8.078e-03	-4.82	Tensin-like_SH2	interpro domains	IPR035012	3	1	18521	50	TNS3
8.078e-03	-4.82	DGK_typeI_N_sf	interpro domains	IPR038199	3	1	18521	50	DGKB
8.078e-03	-4.82	DAG_kinase_typeI_N	interpro domains	IPR029477	3	1	18521	50	DGKB
8.078e-03	-4.82	FARP1/FARP2/FRMD7_FERM_C	interpro domains	IPR041788	3	1	18521	50	FARP1
8.078e-03	-4.82	GPCR_2_brain_angio_inhib	interpro domains	IPR008077	3	1	18521	50	ADGRB3
8.078e-03	-4.82	NR_DBD_ROR	interpro domains	IPR044101	3	1	18521	50	RORA
8.078e-03	-4.82	PHsplit_syntrophin	interpro domains	IPR041428	3	1	18521	50	SNTB1
8.078e-03	-4.82	InsP3_rcpt	interpro domains	IPR000493	3	1	18521	50	ITPR2
8.078e-03	-4.82	Myelin_PLP	interpro domains	IPR001614	3	1	18521	50	GPM6B
8.088e-03	-4.82	amino acid binding	molecular function	GO:0016597	51	2	18094	48	SLC1A3,SLC6A11
8.097e-03	-4.82	regulation of nervous system development	biological process	GO:0051960	456	5	18204	50	PTN,PTPRZ1,QKI,ADGRB3,NTRK2
8.111e-03	-4.81	CTNNB1 (catenin beta 1)	protein interactions	1499	926	7	19454	49	NHSL1,GRIP1,USP6NL,PTPRZ1,CTNND2,PTN,CTBP1
8.181e-03	-4.81	EPM2A (EPM2A glucan phosphatase, laforin)	protein interactions	7957	54	2	19454	49	FKBP5,PREX1
8.181e-03	-4.81	NOS1 (nitric oxide synthase 1)	protein interactions	4842	54	2	19454	49	SNTB1,CTBP1
8.218e-03	-4.80	cysteine transport	biological process	GO:0042883	3	1	18204	50	SLC1A2
8.218e-03	-4.80	negative regulation of neurotransmitter uptake	biological process	GO:0051581	3	1	18204	50	GPM6B
8.218e-03	-4.80	cysteine transmembrane transport	biological process	GO:1903712	3	1	18204	50	SLC1A2
8.218e-03	-4.80	negative regulation of serotonin uptake	biological process	GO:0051612	3	1	18204	50	GPM6B
8.218e-03	-4.80	ossification involved in bone remodeling	biological process	GO:0043932	3	1	18204	50	PTN
8.218e-03	-4.80	trans-synaptic signaling by BDNF, modulating synaptic transmission	biological process	GO:0099183	3	1	18204	50	NTRK2
8.244e-03	-4.80	transmembrane transporter activity	molecular function	GO:0022857	1110	8	18094	48	SLC1A3,ITPR2,SLC39A12,SLC4A4,SLC13A5,AQP4,SLC6A11,SLC1A2
8.271e-03	-4.80	Diacylglycerol kinase alpha	gene3d domains	1.10.238.110	3	1	14470	40	DGKB
8.406e-03	-4.78	DAG_kinase_N	pfam domains	PF14513	3	1	17795	50	DGKB
8.406e-03	-4.78	AGRB_N	pfam domains	PF19188	3	1	17795	50	ADGRB3
8.406e-03	-4.78	LNS2	pfam domains	PF08235	3	1	17795	50	LPIN2
8.406e-03	-4.78	Myelin_PLP	pfam domains	PF01275	3	1	17795	50	GPM6B
8.406e-03	-4.78	Lipin_mid	pfam domains	PF16876	3	1	17795	50	LPIN2
8.406e-03	-4.78	PH_17	pfam domains	PF18012	3	1	17795	50	SNTB1
8.406e-03	-4.78	Lipin_N	pfam domains	PF04571	3	1	17795	50	LPIN2
8.406e-03	-4.78	LRRCT_2	pfam domains	PF16920	3	1	17795	50	NTRK2
8.645e-03	-4.75	Platelet activation, signaling and aggregation	REACTOME pathways	R-HSA-76002	282	4	10285	30	EGF,ITPR2,DGKB,APOA1
8.702e-03	-4.74	learning	biological process	GO:0007612	154	3	18204	50	NTRK2,ADGRB3,PTN
8.726e-03	-4.74	TCF7L2 mutants don't bind CTBP	REACTOME pathways	R-HSA-5339700	3	1	10285	30	CTBP1
8.978e-03	-4.71	cell communication	biological process	GO:0007154	5010	22	18204	50	SLC39A12,SLC1A3,SORCS2,NTRK2,NRCAM,DGKB,PTN,NFIA,ITPK1,GRIP1,GRK5,PREX1,FARP1,APOA1,EGF,ITPR2,RORA,PREX2,FGFRL1,SLC1A2,CTNND2,ADGRB3
8.982e-03	-4.71	regulation of glycolytic process	biological process	GO:0006110	52	2	18204	50	SLC4A4,ZBTB20
8.982e-03	-4.71	regulation of nucleotide catabolic process	biological process	GO:0030811	52	2	18204	50	ZBTB20,SLC4A4
8.982e-03	-4.71	regulation of purine nucleotide catabolic process	biological process	GO:0033121	52	2	18204	50	SLC4A4,ZBTB20
8.982e-03	-4.71	ERK1 and ERK2 cascade	biological process	GO:0070371	52	2	18204	50	APOA1,EGF
9.070e-03	-4.70	KLF8 (KLF transcription factor 8)	protein interactions	11279	326	4	19454	49	CTBP1,NFIA,TRPS1,SOX5
9.139e-03	-4.70	foot	COSMIC cancer mutations	foot	148	3	16828	49	ADAM12,SLC6A11,PREX2
9.172e-03	-4.69	MAPT (microtubule associated protein tau)	protein interactions	4137	948	7	19454	49	FKBP5,GRIP1,FARP1,SLC1A3,CTBP1,CTNND2,SLC1A2
9.190e-03	-4.69	Inositol phosphate metabolism, Ins(1,3,4)P3 => phytate	KEGG pathways	M00132	3	1	7161	22	ITPK1
9.190e-03	-4.69	Inositol phosphate metabolism, Ins(1,3,4)P3 => phytate	KEGG pathways	hsa_M00132	3	1	7161	22	ITPK1
9.206e-03	-4.69	rhabdomyosarcoma	COSMIC cancer mutations	rhabdomyosarcoma	4150	20	16828	49	DGKB,NCKAP5,SLC1A3,CTNND2,NHSL1,PREX2,GRK5,SORCS2,USP6NL,PRDM16,NPAS3,RORA,TRPS1,AQP4,NFIA,PTPRZ1,CTBP1,FHOD3,FGFRL1,ELOVL2
9.212e-03	-4.69	oesophagus-carcinoma-adenocarcinoma	COSMIC cancer mutations	oesophagus-carcinoma-adenocarcinoma	13112	45	16828	49	SLC13A5,FKBP5,NPAS3,TRPS1,SOX5,RFX4,PTPRZ1,SLC39A12,LPIN2,DGKB,NCKAP5,QKI,PTN,NRCAM,NTRK2,ZBTB20,PREX2,SLC4A4,GRIP1,PRDM16,RORA,AQP4,PREX1,FHOD3,FGFRL1,CTBP1,LRIG1,ELOVL2,SLC6A11,ADAM12,SNTB1,EGF,SLC1A3,TNS3,NHSL1,SLC1A2,FARP1,CTNND2,ITPR2,GPC5,GRK5,COL11A1,USP6NL,ITPK1,SORCS2
9.318e-03	-4.68	neutral amino acid transport	biological process	GO:0015804	53	2	18204	50	SLC1A2,SLC1A3
9.318e-03	-4.68	regulation of chondrocyte differentiation	biological process	GO:0032330	53	2	18204	50	TRPS1,SOX5
9.342e-03	-4.67	human chr4p16.3	chromosome location	human chr4p16.3	76	2	26134	50	CTBP1,FGFRL1
9.346e-03	-4.67	LRRNT	interpro domains	IPR000372	54	2	18521	50	NTRK2,LRIG1
9.390e-03	-4.67	CILK1 (ciliogenesis associated kinase 1)	protein interactions	22858	58	2	19454	49	MSI2,FKBP5
9.492e-03	-4.66	monoatomic anion transport	biological process	GO:0006820	159	3	18204	50	SLC1A3,SLC1A2,SLC4A4
9.530e-03	-4.65	human chr13q32.2	chromosome location	human chr13q32.2	5	1	26134	50	FARP1
9.586e-03	-4.65	NME2 (NME/NM23 nucleoside diphosphate kinase 2)	protein interactions	4831	174	3	19454	49	RORA,CTBP1,PREX1
9.659e-03	-4.64	positive regulation of biomineral tissue development	biological process	GO:0070169	54	2	18204	50	PTN,GPM6B
9.659e-03	-4.64	positive regulation of ossification	biological process	GO:0045778	54	2	18204	50	GPM6B,PTN
9.659e-03	-4.64	regulation of cholesterol efflux	biological process	GO:0010874	54	2	18204	50	APOA1,EGF
9.727e-03	-4.63	RORNUCRECPTR	prints domains	PR01293	3	1	5227	17	RORA
9.727e-03	-4.63	INSP3RECEPTR	prints domains	PR00779	3	1	5227	17	ITPR2
9.727e-03	-4.63	NTKRECEPTOR	prints domains	PR01939	3	1	5227	17	NTRK2
9.727e-03	-4.63	MYELINPLP	prints domains	PR00214	3	1	5227	17	GPM6B
9.727e-03	-4.63	BAIPRECURSOR	prints domains	PR01694	3	1	5227	17	ADGRB3
9.736e-03	-4.63	LHX3 (LIM homeobox 3)	protein interactions	8022	175	3	19454	49	NFIA,SOX5,TRPS1
9.751e-03	-4.63	dendritic spine	cellular component	GO:0043197	172	3	19108	49	NTRK2,SORCS2,FARP1
9.819e-03	-4.62	sensory perception of sound	biological process	GO:0007605	161	3	18204	50	COL11A1,SLC1A3,LRIG1
9.858e-03	-4.62	skin-scalp-malignant_melanoma	COSMIC cancer mutations	skin-scalp-malignant_melanoma	634	6	16828	49	PTPRZ1,SLC6A11,PREX2,ADAM12,COL11A1,NFIA
1.001e-02	-4.60	response to cocaine	biological process	GO:0042220	55	2	18204	50	SLC1A2,SLC1A3
1.002e-02	-4.60	Znf_NHR/GATA	interpro domains	IPR013088	56	2	18521	50	TRPS1,RORA
1.004e-02	-4.60	Lrrfip1 (leucine rich repeat (in FLII) interacting protein 1)	protein interactions	16978	4	1	19454	49	GRIP1
1.004e-02	-4.60	APOF (apolipoprotein F)	protein interactions	319	4	1	19454	49	APOA1
1.004e-02	-4.60	Nrip1 (nuclear receptor interacting protein 1)	protein interactions	268903	4	1	19454	49	CTBP1
1.004e-02	-4.60	AVPR1A (arginine vasopressin receptor 1A)	protein interactions	552	4	1	19454	49	GRK5
1.004e-02	-4.60	Nme2 (NME/NM23 nucleoside diphosphate kinase 2)	protein interactions	18103	4	1	19454	49	RORA
1.004e-02	-4.60	GATA3 (GATA binding protein 3)	protein interactions	2625	177	3	19454	49	TRPS1,QKI,NFIA
1.005e-02	-4.60	FAM120A (family with sequence similarity 120 member A)	protein interactions	23196	336	4	19454	49	GRK5,PRDM16,QKI,FKBP5
1.006e-02	-4.60	neuron spine	cellular component	GO:0044309	174	3	19108	49	FARP1,SORCS2,NTRK2
1.009e-02	-4.60	C1_1	pfam domains	PF00130	54	2	17795	50	TNS3,DGKB
1.019e-02	-4.59	ERBB4 (erb-b2 receptor tyrosine kinase 4)	protein interactions	2066	178	3	19454	49	LRIG1,NTRK2,TNS3
1.022e-02	-4.58	collagen type XI trimer	cellular component	GO:0005592	4	1	19108	49	COL11A1
1.027e-02	-4.58	IGc2	smart domains	SM00408	239	4	9717	35	NRCAM,NTRK2,LRIG1,FGFRL1
1.034e-02	-4.57	Metabolism of fat-soluble vitamins	REACTOME pathways	R-HSA-6806667	53	2	10285	30	APOA1,GPC5
1.044e-02	-4.56	Erythroid Transcription Factor GATA-1, subunit A	gene3d domains	3.30.50.10	56	2	14470	40	RORA,TRPS1
1.049e-02	-4.56	import across plasma membrane	biological process	GO:0098739	165	3	18204	50	SLC1A2,SLC39A12,SLC1A3
1.051e-02	-4.56	MYOD1 (myogenic differentiation 1)	protein interactions	4654	180	3	19454	49	NFIA,RORA,TRPS1
1.055e-02	-4.55	MYELIN_PLP_1	prosite domains	PS00575	3	1	12186	43	GPM6B
1.055e-02	-4.55	NA_SULFATE	prosite domains	PS01271	3	1	12186	43	SLC13A5
1.055e-02	-4.55	MYELIN_PLP_2	prosite domains	PS01004	3	1	12186	43	GPM6B
1.057e-02	-4.55	brain-derived neurotrophic factor binding	molecular function	GO:0048403	4	1	18094	48	NTRK2
1.057e-02	-4.55	beta-adrenergic receptor kinase activity	molecular function	GO:0047696	4	1	18094	48	GRK5
1.057e-02	-4.55	apolipoprotein A-I receptor binding	molecular function	GO:0034191	4	1	18094	48	APOA1
1.057e-02	-4.55	tricarboxylic acid transmembrane transporter activity	molecular function	GO:0015142	4	1	18094	48	SLC13A5
1.057e-02	-4.55	citrate transmembrane transporter activity	molecular function	GO:0015137	4	1	18094	48	SLC13A5
1.067e-02	-4.54	MTMR7 (myotubularin related protein 7)	protein interactions	9108	62	2	19454	49	FKBP5,CTBP1
1.071e-02	-4.54	sulfur compound transmembrane transporter activity	molecular function	GO:1901682	59	2	18094	48	SLC1A2,SLC6A11
1.076e-02	-4.53	CTF/NFI_DNA-bd_CS	interpro domains	IPR019739	4	1	18521	50	NFIA
1.076e-02	-4.53	Neurofascin/L1/NrCAM_C	interpro domains	IPR026966	4	1	18521	50	NRCAM
1.076e-02	-4.53	Tensin_PTB	interpro domains	IPR033929	4	1	18521	50	TNS3
1.076e-02	-4.53	NHS-like	interpro domains	IPR024845	4	1	18521	50	NHSL1
1.076e-02	-4.53	CTF/NFI_DNA-bd_N	interpro domains	IPR019548	4	1	18521	50	NFIA
1.076e-02	-4.53	ApoA_E	interpro domains	IPR000074	4	1	18521	50	APOA1
1.076e-02	-4.53	D-isomer_DH_CS	interpro domains	IPR029753	4	1	18521	50	CTBP1
1.076e-02	-4.53	D-isomer_2_OHA_DH_cat_dom	interpro domains	IPR006139	4	1	18521	50	CTBP1
1.076e-02	-4.53	CTF/NFI	interpro domains	IPR000647	4	1	18521	50	NFIA
1.076e-02	-4.53	CTF/NFI_DNA-bd-dom	interpro domains	IPR020604	4	1	18521	50	NFIA
1.076e-02	-4.53	D-isomer_DH_NAD-bd	interpro domains	IPR006140	4	1	18521	50	CTBP1
1.077e-02	-4.53	PLP	smart domains	SM00002	3	1	9717	35	GPM6B
1.079e-02	-4.53	PH_DOMAIN	prosite domains	PS50003	246	4	12186	43	PREX1,SNTB1,PREX2,FARP1
1.080e-02	-4.53	tube morphogenesis	biological process	GO:0035239	685	6	18204	50	RORA,QKI,SLC39A12,EGF,NRCAM,NTRK2
1.094e-02	-4.52	regulation of serotonin uptake	biological process	GO:0051611	4	1	18204	50	GPM6B
1.094e-02	-4.52	positive regulation of mesenchymal stem cell differentiation	biological process	GO:2000741	4	1	18204	50	SOX5
1.094e-02	-4.52	brain-derived neurotrophic factor receptor signaling pathway	biological process	GO:0031547	4	1	18204	50	NTRK2
1.094e-02	-4.52	oxaloacetate transport	biological process	GO:0015729	4	1	18204	50	SLC13A5
1.094e-02	-4.52	gamma-aminobutyric acid reuptake	biological process	GO:0051936	4	1	18204	50	SLC6A11
1.094e-02	-4.52	positive regulation of hyaluronan biosynthetic process	biological process	GO:1900127	4	1	18204	50	EGF
1.094e-02	-4.52	positive regulation of phospholipid efflux	biological process	GO:1902995	4	1	18204	50	APOA1
1.094e-02	-4.52	trans-synaptic signaling by BDNF	biological process	GO:0099191	4	1	18204	50	NTRK2
1.094e-02	-4.52	negative regulation of very-low-density lipoprotein particle remodeling	biological process	GO:0010903	4	1	18204	50	APOA1
1.094e-02	-4.52	regulation of phospholipid efflux	biological process	GO:1902994	4	1	18204	50	APOA1
1.098e-02	-4.51	primitive_neuroectodermal_tumour-medulloblastoma	COSMIC cancer mutations	primitive_neuroectodermal_tumour-medulloblastoma	15350	49	16828	49	SNTB1,EGF,TNS3,ITPR2,GRK5,COL11A1,ITPK1,PRDM16,NFIA,PREX1,FGFRL1,NTRK2,SLC4A4,SLC13A5,NPAS3,SOX5,SLC39A12,APOA1,SLC1A3,NHSL1,FARP1,SLC1A2,CTNND2,GPC5,USP6NL,SORCS2,GRIP1,RORA,AQP4,GPM6B,FHOD3,CTBP1,ELOVL2,LRIG1,SLC6A11,ADAM12,DGKB,NCKAP5,QKI,PTN,NRCAM,ZBTB20,PREX2,MSI2,FKBP5,TRPS1,RFX4,PTPRZ1,LPIN2
1.099e-02	-4.51	QKI (QKI, KH domain containing RNA binding)	protein interactions	9444	183	3	19454	49	SLC39A12,QKI,MSI2
1.101e-02	-4.51	heparin binding	molecular function	GO:0008201	174	3	18094	48	COL11A1,FGFRL1,PTN
1.106e-02	-4.50	(4Z,7Z,10Z,13Z,16Z)-docosa-4,7,10,13,16-pentaenoate biosynthesis (6-desaturase)	BIOCYC pathways	META_PWY-7726	5	1	902	2	ELOVL2
1.106e-02	-4.50	docosahexaenoate biosynthesis III (6-desaturase, mammals)	BIOCYC pathways	META_PWY-7606	5	1	902	2	ELOVL2
1.119e-02	-4.49	2-Hacid_dh	pfam domains	PF00389	4	1	17795	50	CTBP1
1.119e-02	-4.49	Apolipoprotein	pfam domains	PF01442	4	1	17795	50	APOA1
1.119e-02	-4.49	2-Hacid_dh_C	pfam domains	PF02826	4	1	17795	50	CTBP1
1.119e-02	-4.49	CTF_NFI	pfam domains	PF00859	4	1	17795	50	NFIA
1.119e-02	-4.49	Bravo_FIGEY	pfam domains	PF13882	4	1	17795	50	NRCAM
1.119e-02	-4.49	NfI_DNAbd_pre-N	pfam domains	PF10524	4	1	17795	50	NFIA
1.119e-02	-4.49	PKD_4	pfam domains	PF18911	4	1	17795	50	SORCS2
1.119e-02	-4.49	TPR_6	pfam domains	PF13174	4	1	17795	50	FKBP5
1.119e-02	-4.49	NHS	pfam domains	PF15273	4	1	17795	50	NHSL1
1.120e-02	-4.49	cellular response to growth factor stimulus	biological process	GO:0071363	494	5	18204	50	SOX5,FGFRL1,NFIA,NTRK2,APOA1
1.132e-02	-4.48	cognition	biological process	GO:0050890	319	4	18204	50	NTRK2,ADGRB3,PTN,PTPRZ1
1.134e-02	-4.48	VSX1 (visual system homeobox 1)	protein interactions	30813	64	2	19454	49	NFIA,TRPS1
1.138e-02	-4.48	head_neck	COSMIC cancer mutations	head_neck	15361	49	16828	49	NFIA,PRDM16,PREX1,FGFRL1,TNS3,SNTB1,EGF,GRK5,ITPK1,COL11A1,ITPR2,SOX5,NPAS3,SLC13A5,SLC39A12,SLC4A4,NTRK2,GPM6B,AQP4,GRIP1,RORA,SLC6A11,LRIG1,ELOVL2,ADAM12,CTBP1,FHOD3,SLC1A3,CTNND2,SLC1A2,NHSL1,FARP1,APOA1,SORCS2,USP6NL,GPC5,TRPS1,RFX4,FKBP5,LPIN2,PTPRZ1,NRCAM,PTN,DGKB,NCKAP5,QKI,MSI2,PREX2,ZBTB20
1.143e-02	-4.47	human chr14q13.1	chromosome location	human chr14q13.1	6	1	26134	50	NPAS3
1.144e-02	-4.47	anaplastic_carcinoma	COSMIC cancer mutations	anaplastic_carcinoma	856	7	16828	49	NRCAM,NFIA,FARP1,SNTB1,GRK5,COL11A1,FHOD3
1.144e-02	-4.47	thyroid-carcinoma-anaplastic_carcinoma	COSMIC cancer mutations	thyroid-carcinoma-anaplastic_carcinoma	856	7	16828	49	SNTB1,NFIA,FARP1,NRCAM,FHOD3,COL11A1,GRK5
1.160e-02	-4.46	skin-lower_leg-malignant_melanoma-nodular	COSMIC cancer mutations	skin-lower_leg-malignant_melanoma-nodular	4	1	16828	49	PREX2
1.160e-02	-4.46	skin-face-malignant_melanoma-superficial_spreading	COSMIC cancer mutations	skin-face-malignant_melanoma-superficial_spreading	4	1	16828	49	PREX2
1.162e-02	-4.46	PLCG1 events in ERBB2 signaling	REACTOME pathways	R-HSA-1251932	4	1	10285	30	EGF
1.162e-02	-4.46	Reuptake of GABA	REACTOME pathways	R-HSA-888593	4	1	10285	30	SLC6A11
1.165e-02	-4.45	Fosphenytoin (Antiarrhythmic) Metabolism Pathway	SMPDB pathways	SMP0000618	4	1	1369	4	SNTB1
1.171e-02	-4.45	nervous system process	biological process	GO:0050877	1376	9	18204	50	COL11A1,SLC1A3,NRCAM,NTRK2,PTPRZ1,PTN,AQP4,LRIG1,ADGRB3
1.175e-02	-4.44	skeletal system development	biological process	GO:0001501	500	5	18204	50	TRPS1,SOX5,COL11A1,FGFRL1,NFIA
1.177e-02	-4.44	CTBP2 (C-terminal binding protein 2)	protein interactions	1488	352	4	19454	49	TRPS1,MSI2,PRDM16,CTBP1
1.178e-02	-4.44	transmembrane receptor protein tyrosine kinase activity	molecular function	GO:0004714	62	2	18094	48	FGFRL1,NTRK2
1.181e-02	-4.44	C1-like_sf	interpro domains	IPR046349	61	2	18521	50	TNS3,DGKB
1.181e-02	-4.44	Tyr_Pase_cat	interpro domains	IPR003595	61	2	18521	50	PTPRZ1,TNS3
1.181e-02	-4.44	HNF1B (HNF1 homeobox B)	protein interactions	6928	188	3	19454	49	TRPS1,SOX5,NFIA
1.182e-02	-4.44	transmission of nerve impulse	biological process	GO:0019226	60	2	18204	50	NTRK2,NRCAM
1.190e-02	-4.43	gallbladder	COSMIC cancer mutations	gallbladder	2821	15	16828	49	NRCAM,CTNND2,NHSL1,FARP1,PREX2,USP6NL,COL11A1,SLC4A4,ITPR2,TRPS1,GRIP1,PRDM16,LRIG1,SLC39A12,PTPRZ1
1.190e-02	-4.43	biliary_tract-gallbladder-carcinoma-adenocarcinoma	COSMIC cancer mutations	biliary_tract-gallbladder-carcinoma-adenocarcinoma	2821	15	16828	49	FARP1,NHSL1,CTNND2,NRCAM,ITPR2,SLC4A4,COL11A1,USP6NL,PREX2,GRIP1,PRDM16,TRPS1,PTPRZ1,SLC39A12,LRIG1
1.192e-02	-4.43	chemical homeostasis	biological process	GO:0048878	914	7	18204	50	SLC4A4,APOA1,SLC39A12,SLC1A3,ZBTB20,AQP4,RORA
1.192e-02	-4.43	cartilage development	biological process	GO:0051216	173	3	18204	50	COL11A1,SOX5,NFIA
1.203e-02	-4.42	MAML1 (mastermind like transcriptional coactivator 1)	protein interactions	9794	66	2	19454	49	NFIA,CTBP1
1.209e-02	-4.42	kidney	COSMIC cancer mutations	kidney	15380	49	16828	49	SLC13A5,NPAS3,SOX5,SLC39A12,NTRK2,SLC4A4,PRDM16,NFIA,PREX1,FGFRL1,SNTB1,EGF,TNS3,ITPR2,GRK5,COL11A1,ITPK1,FKBP5,TRPS1,RFX4,PTPRZ1,LPIN2,NCKAP5,DGKB,QKI,PTN,NRCAM,ZBTB20,PREX2,MSI2,GRIP1,RORA,AQP4,GPM6B,FHOD3,CTBP1,ELOVL2,LRIG1,SLC6A11,ADAM12,APOA1,SLC1A3,NHSL1,SLC1A2,FARP1,CTNND2,GPC5,USP6NL,SORCS2
1.211e-02	-4.41	TLE3 (TLE family member 3, transcriptional corepressor)	protein interactions	7090	355	4	19454	49	NFIA,FKBP5,TRPS1,QKI
1.219e-02	-4.41	skin-arm-malignant_melanoma	COSMIC cancer mutations	skin-arm-malignant_melanoma	1308	9	16828	49	SLC6A11,ADAM12,SLC4A4,ZBTB20,FHOD3,TRPS1,SNTB1,NPAS3,SLC13A5
1.231e-02	-4.40	GRB2 (growth factor receptor bound protein 2)	protein interactions	2885	769	6	19454	49	EGF,MSI2,ADAM12,SLC1A2,NTRK2,USP6NL
1.253e-02	-4.38	SPATA31A7 (SPATA31 subfamily A member 7)	protein interactions	26165	5	1	19454	49	GRK5
1.253e-02	-4.38	SLC25A36 (solute carrier family 25 member 36)	protein interactions	55186	5	1	19454	49	PTN
1.253e-02	-4.38	PDE1A (phosphodiesterase 1A)	protein interactions	5136	5	1	19454	49	APOA1
1.253e-02	-4.38	RFX4 (regulatory factor X4)	protein interactions	5992	5	1	19454	49	RFX4
1.259e-02	-4.38	regulation of substrate adhesion-dependent cell spreading	biological process	GO:1900024	62	2	18204	50	PREX1,APOA1
1.259e-02	-4.38	regulation of carbohydrate catabolic process	biological process	GO:0043470	62	2	18204	50	SLC4A4,ZBTB20
1.259e-02	-4.38	sulfur compound transport	biological process	GO:0072348	62	2	18204	50	SLC1A2,SLC6A11
1.262e-02	-4.37	Ig-like_fold	interpro domains	IPR013783	721	6	18521	50	NTRK2,PTPRZ1,NRCAM,FGFRL1,LRIG1,SORCS2
1.268e-02	-4.37	MED1 (mediator complex subunit 1)	protein interactions	5469	193	3	19454	49	QKI,RORA,CTBP1
1.274e-02	-4.36	FOXP2 (forkhead box P2)	protein interactions	93986	68	2	19454	49	CTBP1,SOX5
1.282e-02	-4.36	regulation of small molecule metabolic process	biological process	GO:0062012	331	4	18204	50	RORA,SLC4A4,APOA1,ZBTB20
1.287e-02	-4.35	viral life cycle	biological process	GO:0019058	178	3	18204	50	USP6NL,CTBP1,NFIA
1.306e-02	-4.34	lipid homeostasis	biological process	GO:0055088	179	3	18204	50	RORA,APOA1,ZBTB20
1.313e-02	-4.33	response to endogenous stimulus	biological process	GO:0009719	1402	9	18204	50	APOA1,SLC1A3,ITPR2,NTRK2,LPIN2,SLC1A2,NFIA,FGFRL1,SOX5
1.313e-02	-4.33	central_nervous_system-medulla-primitive_neuroectodermal_tumour-medulloblastoma-desmoplastic	COSMIC cancer mutations	central_nervous_system-medulla-primitive_neuroectodermal_tumour-medulloblastoma-desmoplastic	14773	48	16828	49	PTPRZ1,LPIN2,FKBP5,RFX4,TRPS1,ZBTB20,PREX2,MSI2,QKI,DGKB,PTN,NRCAM,FHOD3,CTBP1,ADAM12,LRIG1,ELOVL2,SLC6A11,RORA,GRIP1,AQP4,GPM6B,GPC5,SORCS2,USP6NL,APOA1,NHSL1,SLC1A2,FARP1,CTNND2,SLC1A3,SLC39A12,SLC13A5,NPAS3,SOX5,NTRK2,SLC4A4,FGFRL1,PREX1,PRDM16,NFIA,ITPR2,COL11A1,ITPK1,GRK5,EGF,SNTB1,TNS3
1.313e-02	-4.33	central_nervous_system-medulla-primitive_neuroectodermal_tumour-medulloblastoma-classic	COSMIC cancer mutations	central_nervous_system-medulla-primitive_neuroectodermal_tumour-medulloblastoma-classic	14773	48	16828	49	PREX1,FGFRL1,NFIA,PRDM16,GRK5,ITPK1,COL11A1,ITPR2,TNS3,SNTB1,EGF,SLC39A12,SOX5,NPAS3,SLC13A5,SLC4A4,NTRK2,SLC6A11,LRIG1,ELOVL2,ADAM12,CTBP1,FHOD3,GPM6B,AQP4,GRIP1,RORA,SORCS2,USP6NL,GPC5,SLC1A3,CTNND2,FARP1,SLC1A2,NHSL1,APOA1,LPIN2,PTPRZ1,TRPS1,RFX4,FKBP5,MSI2,PREX2,ZBTB20,PTN,NRCAM,DGKB,QKI
1.313e-02	-4.33	central_nervous_system-medulla-primitive_neuroectodermal_tumour-medulloblastoma	COSMIC cancer mutations	central_nervous_system-medulla-primitive_neuroectodermal_tumour-medulloblastoma	14773	48	16828	49	GRK5,COL11A1,ITPK1,ITPR2,TNS3,SNTB1,EGF,PREX1,FGFRL1,NFIA,PRDM16,SLC4A4,NTRK2,SLC39A12,SOX5,SLC13A5,NPAS3,SORCS2,USP6NL,GPC5,SLC1A3,SLC1A2,NHSL1,FARP1,CTNND2,APOA1,ELOVL2,LRIG1,SLC6A11,ADAM12,FHOD3,CTBP1,AQP4,GPM6B,GRIP1,RORA,PREX2,MSI2,ZBTB20,PTN,NRCAM,DGKB,QKI,LPIN2,PTPRZ1,TRPS1,RFX4,FKBP5
1.313e-02	-4.33	central_nervous_system-medulla-primitive_neuroectodermal_tumour-medulloblastoma-large_cell	COSMIC cancer mutations	central_nervous_system-medulla-primitive_neuroectodermal_tumour-medulloblastoma-large_cell	14773	48	16828	49	SLC39A12,SOX5,NPAS3,SLC13A5,SLC4A4,NTRK2,PREX1,FGFRL1,NFIA,PRDM16,GRK5,ITPK1,COL11A1,ITPR2,TNS3,SNTB1,EGF,LPIN2,PTPRZ1,TRPS1,RFX4,FKBP5,MSI2,PREX2,ZBTB20,NRCAM,PTN,DGKB,QKI,SLC6A11,LRIG1,ELOVL2,ADAM12,CTBP1,FHOD3,GPM6B,AQP4,GRIP1,RORA,SORCS2,USP6NL,GPC5,SLC1A3,CTNND2,NHSL1,FARP1,SLC1A2,APOA1
1.314e-02	-4.33	inorganic ion transmembrane transport	biological process	GO:0098660	715	6	18204	50	SLC4A4,ITPR2,SLC39A12,SLC1A3,SLC13A5,SLC6A11
1.317e-02	-4.33	classic	COSMIC cancer mutations	classic	14774	48	16828	49	SOX5,SLC13A5,NPAS3,SLC39A12,SLC4A4,NTRK2,NFIA,PRDM16,PREX1,FGFRL1,TNS3,SNTB1,EGF,GRK5,COL11A1,ITPK1,ITPR2,TRPS1,RFX4,FKBP5,LPIN2,PTPRZ1,NRCAM,PTN,DGKB,QKI,PREX2,MSI2,ZBTB20,AQP4,GPM6B,GRIP1,RORA,LRIG1,ELOVL2,SLC6A11,ADAM12,FHOD3,CTBP1,SLC1A3,NHSL1,FARP1,SLC1A2,CTNND2,APOA1,USP6NL,SORCS2,GPC5
1.318e-02	-4.33	main axon	cellular component	GO:0044304	68	2	19108	49	SLC1A2,NRCAM
1.320e-02	-4.33	inositol tetrakisphosphate kinase activity	molecular function	GO:0051765	5	1	18094	48	ITPK1
1.320e-02	-4.33	neurotrophin receptor activity	molecular function	GO:0005030	5	1	18094	48	NTRK2
1.320e-02	-4.33	taurine transmembrane transporter activity	molecular function	GO:0005368	5	1	18094	48	SLC6A11
1.320e-02	-4.33	fibroblast growth factor receptor activity	molecular function	GO:0005007	5	1	18094	48	FGFRL1
1.320e-02	-4.33	inositol trisphosphate kinase activity	molecular function	GO:0051766	5	1	18094	48	ITPK1
1.327e-02	-4.32	L-amino acid transmembrane transporter activity	molecular function	GO:0015179	66	2	18094	48	SLC1A3,SLC1A2
1.332e-02	-4.32	human chr8q13.2	chromosome location	human chr8q13.2	7	1	26134	50	PREX2
1.332e-02	-4.32	medulla	COSMIC cancer mutations	medulla	14778	48	16828	49	PREX2,MSI2,ZBTB20,NRCAM,PTN,DGKB,QKI,LPIN2,PTPRZ1,TRPS1,RFX4,FKBP5,SORCS2,USP6NL,GPC5,SLC1A3,NHSL1,FARP1,SLC1A2,CTNND2,APOA1,ELOVL2,LRIG1,SLC6A11,ADAM12,FHOD3,CTBP1,AQP4,GPM6B,GRIP1,RORA,SLC4A4,NTRK2,SLC39A12,SOX5,SLC13A5,NPAS3,GRK5,COL11A1,ITPK1,ITPR2,TNS3,SNTB1,EGF,PREX1,FGFRL1,NFIA,PRDM16
1.336e-02	-4.32	desmoplastic	COSMIC cancer mutations	desmoplastic	14779	48	16828	49	SLC13A5,NPAS3,SOX5,SLC39A12,NTRK2,SLC4A4,PRDM16,NFIA,PREX1,FGFRL1,SNTB1,EGF,TNS3,ITPR2,GRK5,COL11A1,ITPK1,FKBP5,TRPS1,RFX4,PTPRZ1,LPIN2,DGKB,QKI,NRCAM,PTN,ZBTB20,PREX2,MSI2,GRIP1,RORA,AQP4,GPM6B,FHOD3,CTBP1,ELOVL2,LRIG1,SLC6A11,ADAM12,APOA1,SLC1A3,NHSL1,FARP1,SLC1A2,CTNND2,GPC5,USP6NL,SORCS2
1.343e-02	-4.31	Sortilin_N	interpro domains	IPR031778	5	1	18521	50	SORCS2
1.343e-02	-4.31	Sortilin_C	interpro domains	IPR031777	5	1	18521	50	SORCS2
1.343e-02	-4.31	BBP-like	interpro domains	IPR045071	5	1	18521	50	QKI
1.343e-02	-4.31	SLC13A/DASS	interpro domains	IPR001898	5	1	18521	50	SLC13A5
1.343e-02	-4.31	VPS10	interpro domains	IPR006581	5	1	18521	50	SORCS2
1.343e-02	-4.31	Syntrophin	interpro domains	IPR015482	5	1	18521	50	SNTB1
1.343e-02	-4.31	Na/HCO3_transpt	interpro domains	IPR003024	5	1	18521	50	SLC4A4
1.346e-02	-4.31	sodium ion transport	biological process	GO:0006814	181	3	18204	50	SLC4A4,SLC13A5,SLC6A11
1.346e-02	-4.31	TSHZ3 (teashirt zinc finger homeobox 3)	protein interactions	57616	70	2	19454	49	SOX5,CTBP1
1.346e-02	-4.31	ITGB3 (integrin subunit beta 3)	protein interactions	3690	70	2	19454	49	PTPRZ1,PTN
1.348e-02	-4.31	-	gene3d domains	3.30.60.20	64	2	14470	40	DGKB,TNS3
1.349e-02	-4.31	PH	smart domains	SM00233	259	4	9717	35	PREX2,SNTB1,PREX1,FARP1
1.353e-02	-4.30	Immunoglobulins	gene3d domains	2.60.40.10	721	6	14470	40	NRCAM,LRIG1,PTPRZ1,NTRK2,SORCS2,FGFRL1
1.356e-02	-4.30	arm	COSMIC cancer mutations	arm	1331	9	16828	49	SLC6A11,SLC4A4,ADAM12,ZBTB20,FHOD3,TRPS1,SNTB1,SLC13A5,NPAS3
1.357e-02	-4.30	NFIX (nuclear factor I X)	protein interactions	4784	198	3	19454	49	NFIA,SOX5,TRPS1
1.357e-02	-4.30	TPX2 (TPX2 microtubule nucleation factor)	protein interactions	22974	198	3	19454	49	PRDM16,FARP1,PREX1
1.362e-02	-4.30	cell body	cellular component	GO:0044297	556	5	19108	49	SLC1A3,GRIP1,CTNND2,SORCS2,SLC1A2
1.365e-02	-4.29	sterol binding	molecular function	GO:0032934	67	2	18094	48	RORA,APOA1
1.366e-02	-4.29	retrograde trans-synaptic signaling	biological process	GO:0098917	5	1	18204	50	FARP1
1.366e-02	-4.29	otolith morphogenesis	biological process	GO:0032474	5	1	18204	50	LRIG1
1.366e-02	-4.29	synaptic signaling via neuropeptide	biological process	GO:0099538	5	1	18204	50	NTRK2
1.366e-02	-4.29	tendon development	biological process	GO:0035989	5	1	18204	50	COL11A1
1.366e-02	-4.29	tricarboxylic acid transport	biological process	GO:0006842	5	1	18204	50	SLC13A5
1.366e-02	-4.29	citrate transport	biological process	GO:0015746	5	1	18204	50	SLC13A5
1.367e-02	-4.29	neoplasm	COSMIC cancer mutations	neoplasm	14787	48	16828	49	NTRK2,SLC4A4,SLC39A12,SLC13A5,NPAS3,SOX5,ITPR2,COL11A1,ITPK1,GRK5,EGF,SNTB1,TNS3,FGFRL1,PREX1,PRDM16,NFIA,ZBTB20,PREX2,MSI2,QKI,NCKAP5,DGKB,NRCAM,PTN,PTPRZ1,LPIN2,FKBP5,RFX4,TRPS1,GPC5,SORCS2,USP6NL,APOA1,NHSL1,FARP1,SLC1A2,CTNND2,SLC1A3,FHOD3,CTBP1,LRIG1,ELOVL2,SLC6A11,RORA,GRIP1,AQP4,GPM6B
1.372e-02	-4.29	PE/DAG-bd	interpro domains	IPR002219	66	2	18521	50	TNS3,DGKB
1.375e-02	-4.29	-	gene3d domains	3.30.60.270	5	1	14470	40	SORCS2
1.375e-02	-4.29	-	gene3d domains	2.10.70.80	5	1	14470	40	SORCS2
1.375e-02	-4.29	Apolipoprotein	gene3d domains	1.20.120.20	5	1	14470	40	APOA1
1.377e-02	-4.29	positive regulation of synapse assembly	biological process	GO:0051965	65	2	18204	50	NTRK2,ADGRB3
1.383e-02	-4.28	UNKL (unk like zinc finger)	protein interactions	64718	71	2	19454	49	CTBP1,QKI
1.383e-02	-4.28	ANK2 (ankyrin 2)	protein interactions	287	71	2	19454	49	NRCAM,FARP1
1.387e-02	-4.28	Glycerolipid metabolism	KEGG pathways	ko00561	59	2	7161	22	LPIN2,DGKB
1.387e-02	-4.28	Glycerolipid metabolism	KEGG pathways	hsa00561	59	2	7161	22	DGKB,LPIN2
1.391e-02	-4.28	brain development	biological process	GO:0007420	724	6	18204	50	NRCAM,NTRK2,EGF,SLC1A2,RORA,RFX4
1.392e-02	-4.27	extracellular matrix	cellular component	GO:0031012	559	5	19108	49	LRIG1,APOA1,COL11A1,GPC5,PTPRZ1
1.396e-02	-4.27	upper_aerodigestive_tract-head_neck-carcinoma-squamous_cell_carcinoma	COSMIC cancer mutations	upper_aerodigestive_tract-head_neck-carcinoma-squamous_cell_carcinoma	9263	35	16828	49	RORA,PRDM16,GPM6B,NFIA,CTBP1,FHOD3,PREX1,ADAM12,LRIG1,ELOVL2,EGF,SNTB1,CTNND2,NHSL1,FARP1,TNS3,GPC5,ITPR2,SORCS2,USP6NL,COL11A1,GRK5,FKBP5,SLC13A5,TRPS1,SOX5,PTPRZ1,LPIN2,QKI,DGKB,PTN,NTRK2,SLC4A4,MSI2,PREX2
1.397e-02	-4.27	Sortilin_C	pfam domains	PF15901	5	1	17795	50	SORCS2
1.397e-02	-4.27	Sortilin-Vps10	pfam domains	PF15902	5	1	17795	50	SORCS2
1.397e-02	-4.27	Na_sulph_symp	pfam domains	PF00939	5	1	17795	50	SLC13A5
1.402e-02	-4.27	external encapsulating structure	cellular component	GO:0030312	560	5	19108	49	LRIG1,APOA1,COL11A1,PTPRZ1,GPC5
1.404e-02	-4.27	CTF_NFI_1	prosite domains	PS00349	4	1	12186	43	NFIA
1.404e-02	-4.27	CTF_NFI_2	prosite domains	PS51080	4	1	12186	43	NFIA
1.404e-02	-4.27	D_2_HYDROXYACID_DH_3	prosite domains	PS00671	4	1	12186	43	CTBP1
1.413e-02	-4.26	lower_leg	COSMIC cancer mutations	lower_leg	174	3	16828	49	PREX2,SLC6A11,ADAM12
1.418e-02	-4.26	hepatocellular_carcinoma	COSMIC cancer mutations	hepatocellular_carcinoma	14800	48	16828	49	ITPR2,ITPK1,COL11A1,GRK5,EGF,SNTB1,TNS3,FGFRL1,PREX1,PRDM16,NFIA,NTRK2,SLC4A4,SLC39A12,NPAS3,SLC13A5,SOX5,GPC5,USP6NL,SORCS2,APOA1,CTNND2,NHSL1,SLC1A2,FARP1,SLC1A3,CTBP1,FHOD3,ADAM12,SLC6A11,ELOVL2,LRIG1,RORA,GRIP1,GPM6B,AQP4,ZBTB20,PREX2,QKI,NCKAP5,DGKB,PTN,NRCAM,PTPRZ1,LPIN2,FKBP5,RFX4,TRPS1
1.418e-02	-4.26	liver-carcinoma-hepatocellular_carcinoma	COSMIC cancer mutations	liver-carcinoma-hepatocellular_carcinoma	14800	48	16828	49	SLC4A4,NTRK2,SOX5,NPAS3,SLC13A5,SLC39A12,TNS3,SNTB1,EGF,GRK5,ITPK1,COL11A1,ITPR2,NFIA,PRDM16,PREX1,FGFRL1,PTN,NRCAM,DGKB,NCKAP5,QKI,PREX2,ZBTB20,TRPS1,RFX4,FKBP5,LPIN2,PTPRZ1,SLC1A3,CTNND2,NHSL1,FARP1,SLC1A2,APOA1,SORCS2,USP6NL,GPC5,GPM6B,AQP4,GRIP1,RORA,SLC6A11,LRIG1,ELOVL2,ADAM12,CTBP1,FHOD3
1.418e-02	-4.26	L-alpha-amino acid transmembrane transport	biological process	GO:1902475	66	2	18204	50	SLC1A2,SLC1A3
1.420e-02	-4.25	GJA1 (gap junction protein alpha 1)	protein interactions	2697	572	5	19454	49	FARP1,APOA1,SLC39A12,USP6NL,ITPR2
1.427e-02	-4.25	sensory perception of mechanical stimulus	biological process	GO:0050954	185	3	18204	50	SLC1A3,LRIG1,COL11A1
1.427e-02	-4.25	response to growth factor	biological process	GO:0070848	525	5	18204	50	NFIA,SOX5,FGFRL1,APOA1,NTRK2
1.429e-02	-4.25	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-acute_lymphoblastic_leukaemia	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-acute_lymphoblastic_leukaemia	2081	12	16828	49	SLC4A4,PREX2,GRK5,NTRK2,CTBP1,FGFRL1,FHOD3,PTPRZ1,NFIA,SOX5,TRPS1,GRIP1
1.432e-02	-4.25	FEV (FEV transcription factor, ETS family member)	protein interactions	54738	202	3	19454	49	NFIA,SOX5,TRPS1
1.448e-02	-4.24	skin-lower_leg-malignant_melanoma-superficial_spreading	COSMIC cancer mutations	skin-lower_leg-malignant_melanoma-superficial_spreading	5	1	16828	49	PREX2
1.449e-02	-4.23	large_intestine-colon-carcinoma	COSMIC cancer mutations	large_intestine-colon-carcinoma	2612	14	16828	49	SLC13A5,RORA,TRPS1,CTBP1,PTPRZ1,ADAM12,LRIG1,APOA1,FARP1,SLC1A3,GPC5,ITPR2,COL11A1,PREX2
1.450e-02	-4.23	Sodium-coupled sulphate, di- and tri-carboxylate transporters	REACTOME pathways	R-HSA-433137	5	1	10285	30	SLC13A5
1.450e-02	-4.23	Scavenging by Class B Receptors	REACTOME pathways	R-HSA-3000471	5	1	10285	30	APOA1
1.450e-02	-4.23	NGF-independant TRKA activation	REACTOME pathways	R-HSA-187024	5	1	10285	30	NTRK2
1.450e-02	-4.23	MET interacts with TNS proteins	REACTOME pathways	R-HSA-8875513	5	1	10285	30	TNS3
1.451e-02	-4.23	RBMS1 (RNA binding motif single stranded interacting protein 1)	protein interactions	5937	203	3	19454	49	MSI2,GRK5,QKI
1.468e-02	-4.22	phosphate-containing compound metabolic process	biological process	GO:0006796	1681	10	18204	50	NTRK2,APOA1,TNS3,CTBP1,GRK5,ELOVL2,ITPK1,RORA,PTPRZ1,DGKB
1.470e-02	-4.22	NFIC (nuclear factor I C)	protein interactions	4782	204	3	19454	49	NFIA,TRPS1,SOX5
1.480e-02	-4.21	protein-macromolecule adaptor activity	molecular function	GO:0030674	989	7	18094	48	FKBP5,PRDM16,COL11A1,CTBP1,QKI,LPIN2,GRIP1
1.481e-02	-4.21	blood vessel development	biological process	GO:0001568	530	5	18204	50	QKI,RORA,EGF,NTRK2,NRCAM
1.482e-02	-4.21	B3GAT1 (beta-1,3-glucuronyltransferase 1)	protein interactions	27087	377	4	19454	49	ITPR2,ELOVL2,FGFRL1,FARP1
1.502e-02	-4.20	SOX11 (SRY-box transcription factor 11)	protein interactions	6664	6	1	19454	49	SOX5
1.502e-02	-4.20	PRLHR (prolactin releasing hormone receptor)	protein interactions	2834	6	1	19454	49	GRIP1
1.502e-02	-4.20	CFHR1 (complement factor H related 1)	protein interactions	3078	6	1	19454	49	APOA1
1.502e-02	-4.20	PBP2 (Pbp2p)	protein interactions	852533	6	1	19454	49	QKI
1.502e-02	-4.20	SOX1 (SRY-box transcription factor 1)	protein interactions	6656	6	1	19454	49	SOX5
1.502e-02	-4.20	LCAT (lecithin-cholesterol acyltransferase)	protein interactions	3931	6	1	19454	49	APOA1
1.502e-02	-4.20	Map3k12 (mitogen-activated protein kinase kinase kinase 12)	protein interactions	26404	6	1	19454	49	USP6NL
1.502e-02	-4.20	DAZ4 (deleted in azoospermia 4)	protein interactions	57135	6	1	19454	49	QKI
1.503e-02	-4.20	cell junction organization	biological process	GO:0034330	532	5	18204	50	FARP1,NFIA,NRCAM,ADGRB3,CTNND2
1.521e-02	-4.19	human chr7p21.2	chromosome location	human chr7p21.2	8	1	26134	50	DGKB
1.531e-02	-4.18	ERBB2 (erb-b2 receptor tyrosine kinase 2)	protein interactions	2064	583	5	19454	49	TNS3,EGF,LRIG1,NTRK2,GPM6B
1.547e-02	-4.17	GATAD2A (GATA zinc finger domain containing 2A)	protein interactions	54815	208	3	19454	49	TRPS1,SOX5,PRDM16
1.559e-02	-4.16	PH	pfam domains	PF00169	187	3	17795	50	SNTB1,FARP1,PREX2
1.561e-02	-4.16	monoatomic ion transport	biological process	GO:0006811	964	7	18204	50	SLC1A2,SLC1A3,ITPR2,SLC39A12,SLC13A5,SLC4A4,SLC6A11
1.570e-02	-4.15	central_nervous_system-brainstem-primitive_neuroectodermal_tumour-medulloblastoma-WNT_subtype	COSMIC cancer mutations	central_nervous_system-brainstem-primitive_neuroectodermal_tumour-medulloblastoma-WNT_subtype	181	3	16828	49	NCKAP5,EGF,NPAS3
1.573e-02	-4.15	MIR200A (microRNA 200a)	protein interactions	406983	76	2	19454	49	MSI2,QKI
1.581e-02	-4.15	histone H3K9 monomethyltransferase activity	molecular function	GO:0140948	6	1	18094	48	PRDM16
1.581e-02	-4.15	sodium:bicarbonate symporter activity	molecular function	GO:0008510	6	1	18094	48	SLC4A4
1.581e-02	-4.15	phosphatidylcholine-sterol O-acyltransferase activator activity	molecular function	GO:0060228	6	1	18094	48	APOA1
1.581e-02	-4.15	gamma-aminobutyric acid:sodium:chloride symporter activity	molecular function	GO:0005332	6	1	18094	48	SLC6A11
1.581e-02	-4.15	succinate transmembrane transporter activity	molecular function	GO:0015141	6	1	18094	48	SLC13A5
1.593e-02	-4.14	WNT_subtype	COSMIC cancer mutations	WNT_subtype	182	3	16828	49	NCKAP5,NPAS3,EGF
1.595e-02	-4.14	cell projection	cellular component	GO:0042995	2398	12	19108	49	SLC6A11,NRCAM,CTNND2,GRIP1,NTRK2,SORCS2,PREX1,SLC1A3,TNS3,SLC1A2,AQP4,FARP1
1.600e-02	-4.13	other	COSMIC cancer mutations	other	14843	48	16828	49	FHOD3,CTBP1,ELOVL2,LRIG1,SLC6A11,RORA,GRIP1,AQP4,GPM6B,GPC5,USP6NL,SORCS2,APOA1,NHSL1,SLC1A2,FARP1,CTNND2,SLC1A3,PTPRZ1,LPIN2,FKBP5,RFX4,TRPS1,ZBTB20,PREX2,MSI2,QKI,NCKAP5,DGKB,PTN,NRCAM,FGFRL1,PREX1,PRDM16,NFIA,ITPR2,COL11A1,ITPK1,GRK5,EGF,SNTB1,TNS3,SLC39A12,SLC13A5,NPAS3,SOX5,NTRK2,SLC4A4
1.604e-02	-4.13	LRRNT	smart domains	SM00013	54	2	9717	35	NTRK2,LRIG1
1.609e-02	-4.13	RIH_assoc-dom	interpro domains	IPR013662	6	1	18521	50	ITPR2
1.609e-02	-4.13	RIH_dom	interpro domains	IPR000699	6	1	18521	50	ITPR2
1.609e-02	-4.13	Glypican	interpro domains	IPR001863	6	1	18521	50	GPC5
1.609e-02	-4.13	Ryanodine_IP3_receptor	interpro domains	IPR015925	6	1	18521	50	ITPR2
1.609e-02	-4.13	ELO_CS	interpro domains	IPR030457	6	1	18521	50	ELOVL2
1.609e-02	-4.13	Ins145_P3_rcpt	interpro domains	IPR014821	6	1	18521	50	ITPR2
1.609e-02	-4.13	RyR/IP3R_RIH_dom_sf	interpro domains	IPR035910	6	1	18521	50	ITPR2
1.609e-02	-4.13	Glypican_CS	interpro domains	IPR019803	6	1	18521	50	GPC5
1.609e-02	-4.13	LNS2/PITP	interpro domains	IPR031315	6	1	18521	50	LPIN2
1.610e-02	-4.13	central_nervous_system-brain-glioma	COSMIC cancer mutations	central_nervous_system-brain-glioma	15470	49	16828	49	SNTB1,EGF,TNS3,ITPR2,GRK5,ITPK1,COL11A1,PRDM16,NFIA,PREX1,FGFRL1,NTRK2,SLC4A4,NPAS3,SLC13A5,SOX5,SLC39A12,APOA1,SLC1A3,CTNND2,SLC1A2,FARP1,NHSL1,GPC5,SORCS2,USP6NL,GRIP1,RORA,GPM6B,AQP4,CTBP1,FHOD3,SLC6A11,LRIG1,ELOVL2,ADAM12,DGKB,NCKAP5,QKI,NRCAM,PTN,ZBTB20,MSI2,PREX2,FKBP5,TRPS1,RFX4,PTPRZ1,LPIN2
1.613e-02	-4.13	TNS3 (tensin 3)	protein interactions	64759	77	2	19454	49	APOA1,SNTB1
1.613e-02	-4.13	SDC1 (syndecan 1)	protein interactions	6382	77	2	19454	49	FARP1,PTN
1.616e-02	-4.13	NAHCO3TRSPRT	prints domains	PR01232	5	1	5227	17	SLC4A4
1.622e-02	-4.12	phosphorus metabolic process	biological process	GO:0006793	1707	10	18204	50	GRK5,DGKB,RORA,PTPRZ1,ITPK1,ELOVL2,APOA1,NTRK2,CTBP1,TNS3
1.637e-02	-4.11	amino acid neurotransmitter reuptake	biological process	GO:0051933	6	1	18204	50	SLC6A11
1.637e-02	-4.11	succinate transport	biological process	GO:0015744	6	1	18204	50	SLC13A5
1.637e-02	-4.11	positive regulation of cerebellar granule cell precursor proliferation	biological process	GO:0021940	6	1	18204	50	EGF
1.637e-02	-4.11	cell surface receptor protein tyrosine phosphatase signaling pathway	biological process	GO:0007185	6	1	18204	50	PTN
1.637e-02	-4.11	asymmetric neuroblast division	biological process	GO:0055059	6	1	18204	50	SOX5
1.637e-02	-4.11	regulation of synapse pruning	biological process	GO:1905806	6	1	18204	50	ADGRB3
1.637e-02	-4.11	intracellular water homeostasis	biological process	GO:0009992	6	1	18204	50	AQP4
1.637e-02	-4.11	inositol trisphosphate metabolic process	biological process	GO:0032957	6	1	18204	50	ITPK1
1.637e-02	-4.11	positive regulation of skeletal muscle acetylcholine-gated channel clustering	biological process	GO:1904395	6	1	18204	50	FARP1
1.637e-02	-4.11	cholesterol import	biological process	GO:0070508	6	1	18204	50	APOA1
1.637e-02	-4.11	clustering of voltage-gated sodium channels	biological process	GO:0045162	6	1	18204	50	NRCAM
1.637e-02	-4.11	succinate transmembrane transport	biological process	GO:0071422	6	1	18204	50	SLC13A5
1.637e-02	-4.11	regulation of very-low-density lipoprotein particle remodeling	biological process	GO:0010901	6	1	18204	50	APOA1
1.637e-02	-4.11	gamma-aminobutyric acid biosynthetic process	biological process	GO:0009449	6	1	18204	50	SLC1A3
1.647e-02	-4.11	IP3 receptor type 1 binding core, RIH domain	gene3d domains	1.25.10.30	6	1	14470	40	ITPR2
1.648e-02	-4.11	ANKFY1 (ankyrin repeat and FYVE domain containing 1)	protein interactions	51479	213	3	19454	49	GRK5,FARP1,CTBP1
1.652e-02	-4.10	SGK1 (serum/glucocorticoid regulated kinase 1)	protein interactions	6446	78	2	19454	49	SLC1A3,FKBP5
1.652e-02	-4.10	MIR34C (microRNA 34c)	protein interactions	407042	78	2	19454	49	MSI2,QKI
1.652e-02	-4.10	ANKRD40 (ankyrin repeat domain 40)	protein interactions	91369	78	2	19454	49	SOX5,MSI2
1.668e-02	-4.09	transcription repressor complex	cellular component	GO:0017053	77	2	19108	49	PRDM16,CTBP1
1.668e-02	-4.09	NCK1 (NCK adaptor protein 1)	protein interactions	4690	214	3	19454	49	NCKAP5,NHSL1,NTRK2
1.672e-02	-4.09	regulation of ATP metabolic process	biological process	GO:1903578	72	2	18204	50	SLC4A4,ZBTB20
1.674e-02	-4.09	RIH_assoc	pfam domains	PF08454	6	1	17795	50	ITPR2
1.674e-02	-4.09	Glypican	pfam domains	PF01153	6	1	17795	50	GPC5
1.674e-02	-4.09	RYDR_ITPR	pfam domains	PF01365	6	1	17795	50	ITPR2
1.674e-02	-4.09	Ins145_P3_rec	pfam domains	PF08709	6	1	17795	50	ITPR2
1.693e-02	-4.08	DNAJB8 (DnaJ heat shock protein family (Hsp40) member B8)	protein interactions	165721	79	2	19454	49	ZBTB20,FKBP5
1.693e-02	-4.08	KRTAP3-2 (keratin associated protein 3-2)	protein interactions	83897	79	2	19454	49	SLC13A5,ADAM12
1.693e-02	-4.08	PRDM1 (PR/SET domain 1)	protein interactions	639	79	2	19454	49	TRPS1,NFIA
1.693e-02	-4.08	CDKN2D (cyclin dependent kinase inhibitor 2D)	protein interactions	1032	79	2	19454	49	QKI,CTBP1
1.709e-02	-4.07	human chr2q21.2	chromosome location	human chr2q21.2	9	1	26134	50	NCKAP5
1.709e-02	-4.07	GABA-ergic synapse	cellular component	GO:0098982	78	2	19108	49	SLC6A11,CTBP1
1.710e-02	-4.07	Signaling by MET	REACTOME pathways	R-HSA-6806834	69	2	10285	30	TNS3,LRIG1
1.713e-02	-4.07	vasculature development	biological process	GO:0001944	550	5	18204	50	NTRK2,NRCAM,EGF,RORA,QKI
1.716e-02	-4.07	regulation of cartilage development	biological process	GO:0061035	73	2	18204	50	TRPS1,SOX5
1.716e-02	-4.07	vasculogenesis	biological process	GO:0001570	73	2	18204	50	QKI,NTRK2
1.717e-02	-4.06	regulation of multicellular organismal process	biological process	GO:0051239	3113	15	18204	50	SOX5,QKI,PTPRZ1,RORA,ADGRB3,APOA1,EGF,ZBTB20,PTN,GPM6B,TRPS1,ADAM12,PRDM16,NTRK2,SLC39A12
1.733e-02	-4.06	PPP1CA (protein phosphatase 1 catalytic subunit alpha)	protein interactions	100009298	80	2	19454	49	PREX2,FARP1
1.735e-02	-4.05	skin-forearm-malignant_melanoma-superficial_spreading	COSMIC cancer mutations	skin-forearm-malignant_melanoma-superficial_spreading	6	1	16828	49	PREX2
1.735e-02	-4.05	skin-head_neck-malignant_melanoma	COSMIC cancer mutations	skin-head_neck-malignant_melanoma	6	1	16828	49	PREX2
1.735e-02	-4.05	autonomic_ganglia-paraganglioma-benign	COSMIC cancer mutations	autonomic_ganglia-paraganglioma-benign	6	1	16828	49	NHSL1
1.738e-02	-4.05	signaling	biological process	GO:0023052	4968	21	18204	50	PREX1,GRIP1,GRK5,PTN,NFIA,ITPK1,DGKB,SORCS2,NTRK2,SLC39A12,SLC1A3,ADGRB3,SLC1A2,CTNND2,PREX2,FGFRL1,RORA,APOA1,EGF,ITPR2,FARP1
1.738e-02	-4.05	Activation of TRKA receptors	REACTOME pathways	R-HSA-187015	6	1	10285	30	NTRK2
1.750e-02	-4.05	Pum2 (pumilio RNA-binding family member 2)	protein interactions	80913	7	1	19454	49	QKI
1.750e-02	-4.05	ZFYVE28 (zinc finger FYVE-type containing 28)	protein interactions	57732	7	1	19454	49	EGF
1.750e-02	-4.05	C1QL3 (complement C1q like 3)	protein interactions	389941	7	1	19454	49	ADGRB3
1.750e-02	-4.05	SLC16A5 (solute carrier family 16 member 5)	protein interactions	9121	7	1	19454	49	PTPRZ1
1.750e-02	-4.05	FGF5 (fibroblast growth factor 5)	protein interactions	2250	7	1	19454	49	EGF
1.750e-02	-4.05	ABCC12 (ATP binding cassette subfamily C member 12)	protein interactions	94160	7	1	19454	49	NPAS3
1.750e-02	-4.05	CDH10 (cadherin 10)	protein interactions	1008	7	1	19454	49	PTN
1.750e-02	-4.05	ZBTB45 (zinc finger and BTB domain containing 45)	protein interactions	84878	7	1	19454	49	ZBTB20
1.750e-02	-4.05	CETP (cholesteryl ester transfer protein)	protein interactions	1071	7	1	19454	49	APOA1
1.750e-02	-4.05	SAA2 (serum amyloid A2)	protein interactions	6289	7	1	19454	49	APOA1
1.774e-02	-4.03	ZF_DAG_PE_1	prosite domains	PS00479	58	2	12186	43	DGKB,TNS3
1.774e-02	-4.03	SOX17 (SRY-box transcription factor 17)	protein interactions	64321	81	2	19454	49	NFIA,TRPS1
1.774e-02	-4.03	ARNT2 (aryl hydrocarbon receptor nuclear translocator 2)	protein interactions	9915	81	2	19454	49	CTBP1,NPAS3
1.774e-02	-4.03	SPRY4 (sprouty RTK signaling antagonist 4)	protein interactions	81848	81	2	19454	49	ADAM12,NTRK2
1.779e-02	-4.03	Neuronal System	REACTOME pathways	R-HSA-112316	349	4	10285	30	GRIP1,SLC1A2,SLC1A3,SLC6A11
1.782e-02	-4.03	cerebellar climbing fiber to Purkinje cell synapse	cellular component	GO:0150053	7	1	19108	49	ADGRB3
1.788e-02	-4.02	VPS10	smart domains	SM00602	5	1	9717	35	SORCS2
1.791e-02	-4.02	monoatomic cation transport	biological process	GO:0006812	766	6	18204	50	SLC13A5,SLC1A3,ITPR2,SLC39A12,SLC4A4,SLC6A11
1.796e-02	-4.02	G alpha (q) signalling events	REACTOME pathways	R-HSA-416476	192	3	10285	30	GRK5,ITPR2,DGKB
1.799e-02	-4.02	cellular response to stimulus	biological process	GO:0051716	6307	25	18204	50	ZBTB20,ITPR2,PREX2,ADGRB3,SLC1A2,CTNND2,SORCS2,SLC13A5,SLC1A3,SLC39A12,PTN,DGKB,LPIN2,FARP1,APOA1,EGF,FGFRL1,RORA,AQP4,NTRK2,NFIA,ITPK1,PREX1,GRIP1,GRK5
1.815e-02	-4.01	alveolar	COSMIC cancer mutations	alveolar	2414	13	16828	49	NCKAP5,SLC1A3,NHSL1,PREX2,GRK5,USP6NL,SORCS2,NPAS3,TRPS1,NFIA,CTBP1,FHOD3,FGFRL1
1.815e-02	-4.01	soft_tissue-striated_muscle-rhabdomyosarcoma-alveolar	COSMIC cancer mutations	soft_tissue-striated_muscle-rhabdomyosarcoma-alveolar	2414	13	16828	49	NHSL1,SLC1A3,NCKAP5,SORCS2,USP6NL,GRK5,PREX2,NFIA,TRPS1,NPAS3,FHOD3,FGFRL1,CTBP1
1.816e-02	-4.01	B4GALT1 (beta-1,4-galactosyltransferase 1)	protein interactions	2683	82	2	19454	49	SLC39A12,CTBP1
1.816e-02	-4.01	LRRC40 (leucine rich repeat containing 40)	protein interactions	55631	82	2	19454	49	FKBP5,LRIG1
1.837e-02	-4.00	Internalization of ErbB1	Pathway Interaction DB	erbb1_internalization_pathway	34	2	2226	14	LRIG1,EGF
1.838e-02	-4.00	animal organ development	biological process	GO:0048513	2846	14	18204	50	RFX4,PTN,NFIA,NRCAM,NTRK2,COL11A1,SLC1A2,LRIG1,RORA,SOX5,FGFRL1,FHOD3,EGF,APOA1
1.843e-02	-3.99	fatty acid elongase activity	molecular function	GO:0009922	7	1	18094	48	ELOVL2
1.843e-02	-3.99	G protein-coupled receptor kinase activity	molecular function	GO:0004703	7	1	18094	48	GRK5
1.843e-02	-3.99	heparan sulfate binding	molecular function	GO:1904399	7	1	18094	48	COL11A1
1.843e-02	-3.99	histone H3K9me2 methyltransferase activity	molecular function	GO:0140947	7	1	18094	48	PRDM16
1.843e-02	-3.99	apolipoprotein receptor binding	molecular function	GO:0034190	7	1	18094	48	APOA1
1.852e-02	-3.99	myotube differentiation	biological process	GO:0014902	76	2	18204	50	ADGRB3,ADAM12
1.858e-02	-3.99	EPHB6 (EPH receptor B6)	protein interactions	2051	83	2	19454	49	USP6NL,FKBP5
1.858e-02	-3.99	PAX2 (paired box 2)	protein interactions	5076	83	2	19454	49	TRPS1,NFIA
1.875e-02	-3.98	Plakophilin/d_Catenin	interpro domains	IPR028435	7	1	18521	50	CTNND2
1.875e-02	-3.98	GPCR_kinase	interpro domains	IPR000239	7	1	18521	50	GRK5
1.875e-02	-3.98	Aquaporin_transptr	interpro domains	IPR034294	7	1	18521	50	AQP4
1.875e-02	-3.98	ELO_fam	interpro domains	IPR002076	7	1	18521	50	ELOVL2
1.875e-02	-3.98	head development	biological process	GO:0060322	774	6	18204	50	RORA,RFX4,NTRK2,NRCAM,SLC1A2,EGF
1.885e-02	-3.97	UBE2I (ubiquitin conjugating enzyme E2 I)	protein interactions	7329	615	5	19454	49	EGF,TRPS1,SOX5,CTBP1,GRIP1
1.889e-02	-3.97	haematopoietic_and_lymphoid_tissue	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue	14368	47	16828	49	RORA,GRIP1,AQP4,FHOD3,CTBP1,ADAM12,ELOVL2,LRIG1,SLC6A11,SLC1A2,NHSL1,FARP1,CTNND2,SLC1A3,GPC5,USP6NL,SORCS2,FKBP5,RFX4,TRPS1,PTPRZ1,LPIN2,QKI,NCKAP5,DGKB,NRCAM,PTN,ZBTB20,PREX2,MSI2,PRDM16,NFIA,FGFRL1,PREX1,EGF,SNTB1,TNS3,ITPR2,COL11A1,ITPK1,GRK5,SLC13A5,NPAS3,SOX5,SLC39A12,NTRK2,SLC4A4
1.897e-02	-3.96	human chr12p11.23	chromosome location	human chr12p11.23	10	1	26134	50	ITPR2
1.897e-02	-3.96	human chr10p12.33	chromosome location	human chr10p12.33	10	1	26134	50	SLC39A12
1.898e-02	-3.96	regulation of cholesterol transport	biological process	GO:0032374	77	2	18204	50	EGF,APOA1
1.898e-02	-3.96	regulation of sterol transport	biological process	GO:0032371	77	2	18204	50	EGF,APOA1
1.900e-02	-3.96	MAPK12 (mitogen-activated protein kinase 12)	protein interactions	6300	84	2	19454	49	FKBP5,SNTB1
1.904e-02	-3.96	FOXC1 (forkhead box C1)	protein interactions	2296	225	3	19454	49	CTBP1,NFIA,SOX5
1.907e-02	-3.96	fatty acid elongation, unsaturated fatty acid	biological process	GO:0019368	7	1	18204	50	ELOVL2
1.907e-02	-3.96	regulation of oligodendrocyte progenitor proliferation	biological process	GO:0070445	7	1	18204	50	PTPRZ1
1.907e-02	-3.96	fatty acid elongation, polyunsaturated fatty acid	biological process	GO:0034626	7	1	18204	50	ELOVL2
1.907e-02	-3.96	glial cell fate specification	biological process	GO:0021780	7	1	18204	50	NFIA
1.907e-02	-3.96	alpha-ketoglutarate transport	biological process	GO:0015742	7	1	18204	50	SLC13A5
1.907e-02	-3.96	fatty acid elongation, monounsaturated fatty acid	biological process	GO:0034625	7	1	18204	50	ELOVL2
1.907e-02	-3.96	regulation of 3'-UTR-mediated mRNA stabilization	biological process	GO:1905868	7	1	18204	50	QKI
1.907e-02	-3.96	regulation of skeletal muscle acetylcholine-gated channel clustering	biological process	GO:1904393	7	1	18204	50	FARP1
1.907e-02	-3.96	high-density lipoprotein particle clearance	biological process	GO:0034384	7	1	18204	50	APOA1
1.907e-02	-3.96	trans-synaptic signaling by trans-synaptic complex	biological process	GO:0099545	7	1	18204	50	FARP1
1.930e-02	-3.95	WH_DNA-bd_sf	interpro domains	IPR036390	211	3	18521	50	PREX1,PREX2,RFX4
1.937e-02	-3.94	EGFTGF	prints domains	PR00009	6	1	5227	17	EGF
1.943e-02	-3.94	CFAP298 (cilia and flagella associated protein 298)	protein interactions	56683	85	2	19454	49	FKBP5,TRPS1
1.951e-02	-3.94	ELO	pfam domains	PF01151	7	1	17795	50	ELOVL2
1.953e-02	-3.94	trunk	COSMIC cancer mutations	trunk	3554	17	16828	49	CTNND2,SLC1A3,NRCAM,EGF,NCKAP5,SNTB1,DGKB,COL11A1,PREX2,NTRK2,TRPS1,SOX5,NPAS3,FKBP5,PRDM16,SLC6A11,PTPRZ1
1.954e-02	-3.94	transmembrane receptor protein kinase activity	molecular function	GO:0019199	81	2	18094	48	NTRK2,FGFRL1
1.970e-02	-3.93	Bile secretion	KEGG pathways	hsa04976	71	2	7161	22	SLC4A4,AQP4
1.970e-02	-3.93	Bile secretion	KEGG pathways	ko04976	71	2	7161	22	AQP4,SLC4A4
1.973e-02	-3.93	regulation of neurogenesis	biological process	GO:0050767	377	4	18204	50	NTRK2,PTPRZ1,QKI,PTN
1.984e-02	-3.92	Signal Transduction	REACTOME pathways	R-HSA-162582	2547	13	10285	30	FGFRL1,LRIG1,GRK5,CTBP1,PREX1,ADAM12,DGKB,NTRK2,EGF,TNS3,APOA1,GPC5,ITPR2
1.998e-02	-3.91	DEPP1 (DEPP autophagy regulator 1)	protein interactions	11067	8	1	19454	49	QKI
1.998e-02	-3.91	FSTL3 (follistatin like 3)	protein interactions	10272	8	1	19454	49	ADAM12
1.998e-02	-3.91	MARCHF10 (membrane associated ring-CH-type finger 10)	protein interactions	162333	8	1	19454	49	CTBP1
1.998e-02	-3.91	CNMD (chondromodulin)	protein interactions	11061	8	1	19454	49	APOA1
1.998e-02	-3.91	PDE6B (phosphodiesterase 6B)	protein interactions	5158	8	1	19454	49	CTBP1
1.998e-02	-3.91	HSD11B2 (hydroxysteroid 11-beta dehydrogenase 2)	protein interactions	3291	8	1	19454	49	CTBP1
1.998e-02	-3.91	GLYAT (glycine-N-acyltransferase)	protein interactions	10249	8	1	19454	49	PTN
2.018e-02	-3.90	positive regulation of GTPase activity	biological process	GO:0043547	211	3	18204	50	PREX2,USP6NL,PREX1
2.019e-02	-3.90	PTPc_motif	smart domains	SM00404	61	2	9717	35	PTPRZ1,TNS3
2.021e-02	-3.90	skin-upper_leg-malignant_melanoma-nodular	COSMIC cancer mutations	skin-upper_leg-malignant_melanoma-nodular	7	1	16828	49	PREX2
2.021e-02	-3.90	skin-face-malignant_melanoma-nodular	COSMIC cancer mutations	skin-face-malignant_melanoma-nodular	7	1	16828	49	PREX2
2.025e-02	-3.90	Neurofascin interactions	REACTOME pathways	R-HSA-447043	7	1	10285	30	NRCAM
2.025e-02	-3.90	NrCAM interactions	REACTOME pathways	R-HSA-447038	7	1	10285	30	NRCAM
2.029e-02	-3.90	ZNF608 (zinc finger protein 608)	protein interactions	57507	87	2	19454	49	NFIA,SOX5
2.029e-02	-3.90	Kctd5 (potassium channel tetramerisation domain containing 5)	protein interactions	69259	87	2	19454	49	SLC1A3,TRPS1
2.029e-02	-3.90	NHLH1 (nescient helix-loop-helix 1)	protein interactions	4807	87	2	19454	49	NFIA,TRPS1
2.029e-02	-3.90	MIR141 (microRNA 141)	protein interactions	406933	87	2	19454	49	QKI,MSI2
2.034e-02	-3.90	extrinsic component of postsynaptic membrane	cellular component	GO:0098890	8	1	19108	49	FARP1
2.034e-02	-3.90	spherical high-density lipoprotein particle	cellular component	GO:0034366	8	1	19108	49	APOA1
2.042e-02	-3.89	enzyme regulator activity	molecular function	GO:0030234	1305	8	18094	48	PTN,EGF,USP6NL,PREX1,ADGRB3,FARP1,APOA1,PREX2
2.044e-02	-3.89	Signaling by EGFR	REACTOME pathways	R-HSA-177929	364	4	10285	30	ADAM12,LRIG1,EGF,ITPR2
2.062e-02	-3.88	CDC23 (cell division cycle 23)	protein interactions	8697	232	3	19454	49	CTBP1,SOX5,FHOD3
2.073e-02	-3.88	ZF_DAG_PE_2	prosite domains	PS50081	63	2	12186	43	DGKB,TNS3
2.073e-02	-3.88	stomach	COSMIC cancer mutations	stomach	15550	49	16828	49	FGFRL1,PREX1,NFIA,PRDM16,ITPK1,COL11A1,GRK5,ITPR2,TNS3,EGF,SNTB1,SLC39A12,SOX5,NPAS3,SLC13A5,SLC4A4,NTRK2,ADAM12,SLC6A11,LRIG1,ELOVL2,CTBP1,FHOD3,GPM6B,AQP4,RORA,GRIP1,USP6NL,SORCS2,GPC5,CTNND2,FARP1,NHSL1,SLC1A2,SLC1A3,APOA1,LPIN2,PTPRZ1,RFX4,TRPS1,FKBP5,MSI2,PREX2,ZBTB20,PTN,NRCAM,QKI,NCKAP5,DGKB
2.092e-02	-3.87	transmembrane transport	biological process	GO:0055085	1264	8	18204	50	SLC6A11,SLC4A4,SLC1A3,SLC39A12,ITPR2,SLC13A5,AQP4,SLC1A2
2.099e-02	-3.86	GLYPICAN	prosite domains	PS01207	6	1	12186	43	GPC5
2.099e-02	-3.86	ELO	prosite domains	PS01188	6	1	12186	43	ELOVL2
2.103e-02	-3.86	glutamate binding	molecular function	GO:0016595	8	1	18094	48	SLC1A3
2.106e-02	-3.86	eye-uveal_tract-malignant_melanoma-spindle	COSMIC cancer mutations	eye-uveal_tract-malignant_melanoma-spindle	363	4	16828	49	FGFRL1,CTNND2,GRK5,PREX2
2.109e-02	-3.86	HMG20A (high mobility group 20A)	protein interactions	10363	234	3	19454	49	NFIA,SNTB1,SOX5
2.115e-02	-3.86	Cys-rich_flank_reg_C	interpro domains	IPR000483	83	2	18521	50	LRIG1,NTRK2
2.117e-02	-3.86	intracellular chemical homeostasis	biological process	GO:0055082	581	5	18204	50	AQP4,ZBTB20,SLC1A3,SLC39A12,SLC4A4
2.117e-02	-3.85	SOX10 (SRY-box transcription factor 10)	protein interactions	6663	89	2	19454	49	NFIA,TRPS1
2.125e-02	-3.85	acute_lymphoblastic_leukaemia	COSMIC cancer mutations	acute_lymphoblastic_leukaemia	2197	12	16828	49	SLC4A4,PREX2,GRK5,NTRK2,NFIA,SOX5,TRPS1,GRIP1,FHOD3,FGFRL1,CTBP1,PTPRZ1
2.126e-02	-3.85	femur	COSMIC cancer mutations	femur	1197	8	16828	49	LRIG1,ELOVL2,SLC4A4,PREX1,PTPRZ1,GPC5,NCKAP5,SNTB1
2.130e-02	-3.85	leg	COSMIC cancer mutations	leg	969	7	16828	49	EGF,ZBTB20,PTPRZ1,SLC4A4,COL11A1,SLC6A11,GRK5
2.135e-02	-3.85	regulation of bone mineralization	biological process	GO:0030500	82	2	18204	50	PTN,GPM6B
2.140e-02	-3.84	RFX-like	interpro domains	IPR039779	8	1	18521	50	RFX4
2.140e-02	-3.84	PKD/Chitinase_dom	interpro domains	IPR022409	8	1	18521	50	SORCS2
2.140e-02	-3.84	DAD_dom	interpro domains	IPR014767	8	1	18521	50	FHOD3
2.140e-02	-3.84	Tensin_phosphatase	interpro domains	IPR029023	8	1	18521	50	TNS3
2.140e-02	-3.84	Tensin_C2-dom	interpro domains	IPR014020	8	1	18521	50	TNS3
2.140e-02	-3.84	PTB	interpro domains	IPR013625	8	1	18521	50	TNS3
2.142e-02	-3.84	LNS2	smart domains	SM00775	6	1	9717	35	LPIN2
2.153e-02	-3.84	Ig_sub	interpro domains	IPR003599	394	4	18521	50	NRCAM,NTRK2,LRIG1,FGFRL1
2.174e-02	-3.83	pancreas-carcinoma-ductal_carcinoma	COSMIC cancer mutations	pancreas-carcinoma-ductal_carcinoma	15565	49	16828	49	AQP4,GPM6B,GRIP1,RORA,LRIG1,ELOVL2,SLC6A11,ADAM12,FHOD3,CTBP1,SLC1A3,SLC1A2,FARP1,NHSL1,CTNND2,APOA1,USP6NL,SORCS2,GPC5,TRPS1,RFX4,FKBP5,LPIN2,PTPRZ1,NRCAM,PTN,NCKAP5,DGKB,QKI,PREX2,MSI2,ZBTB20,NFIA,PRDM16,PREX1,FGFRL1,TNS3,SNTB1,EGF,GRK5,COL11A1,ITPK1,ITPR2,SOX5,SLC13A5,NPAS3,SLC39A12,SLC4A4,NTRK2
2.177e-02	-3.83	alkanesulfonate transmembrane transport	biological process	GO:0042918	8	1	18204	50	SLC6A11
2.177e-02	-3.83	tachykinin receptor signaling pathway	biological process	GO:0007217	8	1	18204	50	GRK5
2.177e-02	-3.83	positive regulation of epithelial tube formation	biological process	GO:1905278	8	1	18204	50	EGF
2.177e-02	-3.83	positive regulation of CoA-transferase activity	biological process	GO:1905920	8	1	18204	50	APOA1
2.177e-02	-3.83	regulation of Cdc42 protein signal transduction	biological process	GO:0032489	8	1	18204	50	APOA1
2.177e-02	-3.83	taurine transmembrane transport	biological process	GO:0015734	8	1	18204	50	SLC6A11
2.177e-02	-3.83	regulation of hyaluronan biosynthetic process	biological process	GO:1900125	8	1	18204	50	EGF
2.177e-02	-3.83	plasma membrane to endosome transport	biological process	GO:0048227	8	1	18204	50	USP6NL
2.177e-02	-3.83	regulation of epithelial tube formation	biological process	GO:1905276	8	1	18204	50	EGF
2.177e-02	-3.83	leukocyte chemotaxis involved in inflammatory response	biological process	GO:0002232	8	1	18204	50	PTN
2.177e-02	-3.83	ERBB2-EGFR signaling pathway	biological process	GO:0038134	8	1	18204	50	EGF
2.177e-02	-3.83	motor learning	biological process	GO:0061743	8	1	18204	50	ADGRB3
2.177e-02	-3.83	fatty acid elongation, saturated fatty acid	biological process	GO:0019367	8	1	18204	50	ELOVL2
2.177e-02	-3.83	gamma-aminobutyric acid metabolic process	biological process	GO:0009448	8	1	18204	50	SLC1A3
2.177e-02	-3.83	positive regulation of neuron projection arborization	biological process	GO:0150012	8	1	18204	50	GRIP1
2.191e-02	-3.82	-	gene3d domains	2.60.40.1110	8	1	14470	40	TNS3
2.207e-02	-3.81	FOXI1 (forkhead box I1)	protein interactions	2299	91	2	19454	49	TRPS1,NFIA
2.207e-02	-3.81	NEIL3 (nei like DNA glycosylase 3)	protein interactions	55247	91	2	19454	49	FKBP5,QKI
2.210e-02	-3.81	response to stimulus	biological process	GO:0050896	7803	29	18204	50	AQP4,FGFRL1,SOX5,RORA,EGF,APOA1,FARP1,LPIN2,PREX1,GRK5,GRIP1,ITPK1,NFIA,NTRK2,COL11A1,ADGRB3,CTNND2,SLC1A2,PREX2,ZBTB20,ITPR2,SLC6A11,PTN,DGKB,SORCS2,SLC1A3,SLC39A12,SLC13A5,FKBP5
2.224e-02	-3.81	regulation of synaptic plasticity	biological process	GO:0048167	219	3	18204	50	SORCS2,NTRK2,PTN
2.224e-02	-3.81	HNRNPL (heterogeneous nuclear ribonucleoprotein L)	protein interactions	3191	1958	10	19454	49	QKI,MSI2,TRPS1,FKBP5,NFIA,FGFRL1,FARP1,ITPK1,ZBTB20,CTBP1
2.226e-02	-3.80	PTB	pfam domains	PF08416	8	1	17795	50	TNS3
2.226e-02	-3.80	PTEN_C2	pfam domains	PF10409	8	1	17795	50	TNS3
2.233e-02	-3.80	regulation of stem cell differentiation	biological process	GO:2000736	84	2	18204	50	PTN,SOX5
2.233e-02	-3.80	L-amino acid transport	biological process	GO:0015807	84	2	18204	50	SLC1A2,SLC1A3
2.245e-02	-3.80	SOBP (sine oculis binding protein homolog)	protein interactions	55084	9	1	19454	49	CTBP1
2.245e-02	-3.80	ABCA6 (ATP binding cassette subfamily A member 6)	protein interactions	23460	9	1	19454	49	APOA1
2.245e-02	-3.80	Prmt5 (protein arginine N-methyltransferase 5)	protein interactions	27374	9	1	19454	49	FARP1
2.245e-02	-3.80	Kif18a (kinesin family member 18A)	protein interactions	228421	9	1	19454	49	CTBP1
2.245e-02	-3.80	ABI3BP (ABI family member 3 binding protein)	protein interactions	25890	9	1	19454	49	GRK5
2.245e-02	-3.80	SPEF2 (sperm flagellar 2)	protein interactions	79925	9	1	19454	49	APOA1
2.245e-02	-3.80	Ywhag (tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide)	protein interactions	22628	9	1	19454	49	QKI
2.250e-02	-3.79	response to mechanical stimulus	biological process	GO:0009612	220	3	18204	50	SLC1A3,PTN,COL11A1
2.253e-02	-3.79	SOX9 (SRY-box transcription factor 9)	protein interactions	6662	92	2	19454	49	NFIA,TRPS1
2.256e-02	-3.79	GPCRKINASE	prints domains	PR00717	7	1	5227	17	GRK5
2.260e-02	-3.79	Tyr_Pase_dom	interpro domains	IPR000387	86	2	18521	50	PTPRZ1,TNS3
2.272e-02	-3.78	human chr6q26	chromosome location	human chr6q26	12	1	26134	50	QKI
2.274e-02	-3.78	lipid biosynthetic process	biological process	GO:0008610	592	5	18204	50	ELOVL2,LPIN2,DGKB,QKI,APOA1
2.275e-02	-3.78	C1	smart domains	SM00109	65	2	9717	35	DGKB,TNS3
2.277e-02	-3.78	regulation of cell-substrate adhesion	biological process	GO:0010810	221	3	18204	50	PREX1,APOA1,GPM6B
2.279e-02	-3.78	oesophagus	COSMIC cancer mutations	oesophagus	14970	48	16828	49	PREX2,ZBTB20,PTN,NRCAM,QKI,DGKB,NCKAP5,LPIN2,PTPRZ1,RFX4,TRPS1,FKBP5,USP6NL,SORCS2,GPC5,CTNND2,NHSL1,FARP1,SLC1A2,SLC1A3,APOA1,ADAM12,SLC6A11,LRIG1,ELOVL2,CTBP1,FHOD3,GPM6B,AQP4,RORA,GRIP1,SLC4A4,NTRK2,SLC39A12,SOX5,NPAS3,SLC13A5,ITPK1,COL11A1,GRK5,ITPR2,TNS3,EGF,SNTB1,FGFRL1,PREX1,NFIA,PRDM16
2.283e-02	-3.78	Ectoderm Differentiation	WikiPathways	WP2858	143	3	5310	23	CTNND2,ELOVL2,CTBP1
2.283e-02	-3.78	chondrocyte differentiation	biological process	GO:0002062	85	2	18204	50	SOX5,COL11A1
2.285e-02	-3.78	platelet dense tubular network membrane	cellular component	GO:0031095	9	1	19108	49	ITPR2
2.285e-02	-3.78	astrocyte end-foot	cellular component	GO:0097450	9	1	19108	49	AQP4
2.299e-02	-3.77	TEX11 (testis expressed 11)	protein interactions	56159	93	2	19454	49	SOX5,QKI
2.299e-02	-3.77	MIR19B2 (microRNA 19b-2)	protein interactions	406981	93	2	19454	49	QKI,MSI2
2.299e-02	-3.77	RBM23 (RNA binding motif protein 23)	protein interactions	55147	93	2	19454	49	QKI,PTN
2.306e-02	-3.77	central_nervous_system-chiasm-glioma-astrocytoma_Grade_I	COSMIC cancer mutations	central_nervous_system-chiasm-glioma-astrocytoma_Grade_I	8	1	16828	49	QKI
2.306e-02	-3.77	skin-chest-malignant_melanoma-nodular	COSMIC cancer mutations	skin-chest-malignant_melanoma-nodular	8	1	16828	49	PREX2
2.309e-02	-3.77	salivary_gland-parotid-carcinoma-adenoid_cystic_carcinoma	COSMIC cancer mutations	salivary_gland-parotid-carcinoma-adenoid_cystic_carcinoma	561	5	16828	49	ITPK1,GRK5,NRCAM,PRDM16,NTRK2
2.311e-02	-3.77	Release of Hh-Np from the secreting cell	REACTOME pathways	R-HSA-5362798	8	1	10285	30	GPC5
2.331e-02	-3.76	glycerolipid biosynthetic process	biological process	GO:0045017	223	3	18204	50	APOA1,LPIN2,DGKB
2.345e-02	-3.75	QSER1 (glutamine and serine rich 1)	protein interactions	79832	94	2	19454	49	SOX5,NFIA
2.345e-02	-3.75	FOXP4 (forkhead box P4)	protein interactions	116113	94	2	19454	49	SOX5,NFIA
2.345e-02	-3.75	TTR (transthyretin)	protein interactions	7276	94	2	19454	49	CTNND2,APOA1
2.361e-02	-3.75	regulation of biological quality	biological process	GO:0065008	2936	14	18204	50	NTRK2,NRCAM,SORCS2,GRIP1,PREX1,DGKB,ITPK1,PTN,APOA1,SLC4A4,FARP1,AQP4,ADGRB3,QKI
2.363e-02	-3.75	chondroitin sulfate binding	molecular function	GO:0035374	9	1	18094	48	PTN
2.363e-02	-3.75	gamma-aminobutyric acid transmembrane transporter activity	molecular function	GO:0015185	9	1	18094	48	SLC6A11
2.364e-02	-3.74	Triglyceride Biosynthesis	REACTOME pathways	R-HSA-75109	82	2	10285	30	LPIN2,ELOVL2
2.376e-02	-3.74	TAB1 (TGF-beta activated kinase 1 (MAP3K7) binding protein 1)	protein interactions	10454	245	3	19454	49	GRK5,FKBP5,FARP1
2.380e-02	-3.74	alcohol binding	molecular function	GO:0043178	90	2	18094	48	ITPR2,APOA1
2.381e-02	-3.74	collagen-containing extracellular matrix	cellular component	GO:0062023	428	4	19108	49	PTPRZ1,GPC5,COL11A1,APOA1
2.384e-02	-3.74	Regulation of RAC1 activity	Pathway Interaction DB	rac1_reg_pathway	39	2	2226	14	PREX2,PREX1
2.385e-02	-3.74	striated muscle cell differentiation	biological process	GO:0051146	225	3	18204	50	FHOD3,ADGRB3,ADAM12
2.388e-02	-3.73	hand	COSMIC cancer mutations	hand	566	5	16828	49	SLC13A5,PREX1,FARP1,SLC4A4,PREX2
2.404e-02	-3.73	Band3_cytoplasmic_dom	interpro domains	IPR013769	9	1	18521	50	SLC4A4
2.404e-02	-3.73	DNA-bd_RFX	interpro domains	IPR003150	9	1	18521	50	RFX4
2.438e-02	-3.71	SPIN1 (spindlin 1)	protein interactions	10927	96	2	19454	49	PTN,GRK5
2.446e-02	-3.71	zinc ion import across plasma membrane	biological process	GO:0071578	9	1	18204	50	SLC39A12
2.446e-02	-3.71	positive regulation of protein localization to early endosome	biological process	GO:1902966	9	1	18204	50	EGF
2.446e-02	-3.71	regulation of intestinal cholesterol absorption	biological process	GO:0030300	9	1	18204	50	APOA1
2.446e-02	-3.71	negative regulation of neurotransmitter transport	biological process	GO:0051589	9	1	18204	50	GPM6B
2.446e-02	-3.71	diaphragm development	biological process	GO:0060539	9	1	18204	50	FGFRL1
2.446e-02	-3.71	regulation of cerebellar granule cell precursor proliferation	biological process	GO:0021936	9	1	18204	50	EGF
2.446e-02	-3.71	regulation of protein localization to early endosome	biological process	GO:1902965	9	1	18204	50	EGF
2.452e-02	-3.71	NCOR2 (nuclear receptor corepressor 2)	protein interactions	9612	248	3	19454	49	SOX5,NFIA,CTBP1
2.454e-02	-3.71	acinar_carcinoma	COSMIC cancer mutations	acinar_carcinoma	1978	11	16828	49	ADAM12,SORCS2,GRK5,FHOD3,SLC39A12,ZBTB20,PTPRZ1,CTNND2,NHSL1,SOX5,QKI
2.454e-02	-3.71	pancreas-carcinoma-acinar_carcinoma	COSMIC cancer mutations	pancreas-carcinoma-acinar_carcinoma	1978	11	16828	49	FHOD3,ZBTB20,SLC39A12,PTPRZ1,SORCS2,ADAM12,GRK5,QKI,CTNND2,NHSL1,SOX5
2.456e-02	-3.71	Protein tyrosine phosphatase superfamily	gene3d domains	3.90.190.10	88	2	14470	40	TNS3,PTPRZ1
2.459e-02	-3.71	human chr1p21.1	chromosome location	human chr1p21.1	13	1	26134	50	COL11A1
2.461e-02	-3.70	-	gene3d domains	1.25.40.610	9	1	14470	40	ADGRB3
2.470e-02	-3.70	WH-like_DNA-bd_sf	interpro domains	IPR036388	232	3	18521	50	PREX1,PREX2,RFX4
2.475e-02	-3.70	RHOQ (ras homolog family member Q)	protein interactions	23433	441	4	19454	49	USP6NL,TNS3,FARP1,SNTB1
2.486e-02	-3.69	PCGF5 (polycomb group ring finger 5)	protein interactions	84333	97	2	19454	49	CTBP1,QKI
2.488e-02	-3.69	skin-foot-malignant_melanoma	COSMIC cancer mutations	skin-foot-malignant_melanoma	84	2	16828	49	SLC6A11,ADAM12
2.491e-02	-3.69	BANK1 (B cell scaffold protein with ankyrin repeats 1)	protein interactions	55024	10	1	19454	49	ITPR2
2.491e-02	-3.69	Mrpl13 (mitochondrial ribosomal protein L13)	protein interactions	68537	10	1	19454	49	QKI
2.491e-02	-3.69	GUCA1B (guanylate cyclase activator 1B)	protein interactions	2979	10	1	19454	49	CTBP1
2.491e-02	-3.69	IGKV2-40 (immunoglobulin kappa variable 2-40)	protein interactions	28916	10	1	19454	49	APOA1
2.491e-02	-3.69	Hsp90aa1 (heat shock protein 90, alpha (cytosolic), class A member 1)	protein interactions	15519	10	1	19454	49	QKI
2.491e-02	-3.69	GPLD1 (glycosylphosphatidylinositol specific phospholipase D1)	protein interactions	2822	10	1	19454	49	APOA1
2.491e-02	-3.69	P2rx7 (purinergic receptor P2X 7)	protein interactions	29665	10	1	19454	49	PTPRZ1
2.491e-02	-3.69	CDKL4 (cyclin dependent kinase like 4)	protein interactions	344387	10	1	19454	49	FKBP5
2.491e-02	-3.69	GRM3 (glutamate metabotropic receptor 3)	protein interactions	2913	10	1	19454	49	GRIP1
2.496e-02	-3.69	DNA-binding transcription factor activity, RNA polymerase II-specific	molecular function	GO:0000981	1355	8	18094	48	PRDM16,SOX5,NFIA,ZBTB20,RFX4,NPAS3,TRPS1,RORA
2.501e-02	-3.69	Band_3_cyto	pfam domains	PF07565	9	1	17795	50	SLC4A4
2.501e-02	-3.69	RFX_DNA_binding	pfam domains	PF02257	9	1	17795	50	RFX4
2.534e-02	-3.68	DMD (dystrophin)	protein interactions	1756	98	2	19454	49	TNS3,SNTB1
2.534e-02	-3.68	PSMF1 (proteasome inhibitor subunit 1)	protein interactions	9491	98	2	19454	49	QKI,CTBP1
2.534e-02	-3.68	MED27 (mediator complex subunit 27)	protein interactions	9442	98	2	19454	49	QKI,SOX5
2.536e-02	-3.67	perineuronal net	cellular component	GO:0072534	10	1	19108	49	PTPRZ1
2.539e-02	-3.67	regulation of purine nucleotide metabolic process	biological process	GO:1900542	90	2	18204	50	SLC4A4,ZBTB20
2.551e-02	-3.67	lipid binding	molecular function	GO:0008289	861	6	18094	48	APOA1,ITPR2,PREX1,DGKB,GRK5,RORA
2.568e-02	-3.66	spindle	COSMIC cancer mutations	spindle	386	4	16828	49	FGFRL1,CTNND2,GRK5,PREX2
2.574e-02	-3.66	GATAZNFINGER	prints domains	PR00619	8	1	5227	17	TRPS1
2.581e-02	-3.66	PRKAA1 (protein kinase AMP-activated catalytic subunit alpha 1)	protein interactions	5562	253	3	19454	49	FKBP5,SLC4A4,CTBP1
2.581e-02	-3.66	connective tissue development	biological process	GO:0061448	232	3	18204	50	NFIA,SOX5,COL11A1
2.582e-02	-3.66	KRTAP9-8 (keratin associated protein 9-8)	protein interactions	83901	99	2	19454	49	SLC13A5,ADAM12
2.582e-02	-3.66	ZFHX3 (zinc finger homeobox 3)	protein interactions	463	99	2	19454	49	TRPS1,SOX5
2.586e-02	-3.66	parotid	COSMIC cancer mutations	parotid	578	5	16828	49	ITPK1,GRK5,NRCAM,PRDM16,NTRK2
2.591e-02	-3.65	skin-upper_leg-malignant_melanoma-superficial_spreading	COSMIC cancer mutations	skin-upper_leg-malignant_melanoma-superficial_spreading	9	1	16828	49	PREX2
2.591e-02	-3.65	skin-chest-malignant_melanoma-superficial_spreading	COSMIC cancer mutations	skin-chest-malignant_melanoma-superficial_spreading	9	1	16828	49	PREX2
2.592e-02	-3.65	regulation of nucleotide metabolic process	biological process	GO:0006140	91	2	18204	50	ZBTB20,SLC4A4
2.600e-02	-3.65	Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain	gene3d domains	1.10.10.10	232	3	14470	40	PREX2,PREX1,RFX4
2.622e-02	-3.64	neurotrophin binding	molecular function	GO:0043121	10	1	18094	48	NTRK2
2.622e-02	-3.64	FK506 binding	molecular function	GO:0005528	10	1	18094	48	FKBP5
2.625e-02	-3.64	cell surface	cellular component	GO:0009986	896	6	19108	49	AQP4,SLC1A2,GPC5,SLC4A4,SLC1A3,NRCAM
2.630e-02	-3.64	CIC (capicua transcriptional repressor)	protein interactions	23152	671	5	19454	49	TRPS1,SOX5,FARP1,CTBP1,NFIA
2.630e-02	-3.64	DTNB (dystrobrevin beta)	protein interactions	1838	100	2	19454	49	SNTB1,TNS3
2.634e-02	-3.64	DYNLL2 (dynein light chain LC8-type 2)	protein interactions	140735	255	3	19454	49	NFIA,NHSL1,TRPS1
2.641e-02	-3.63	positive regulation of nucleobase-containing compound metabolic process	biological process	GO:0045935	2118	11	18204	50	QKI,RORA,NPAS3,EGF,ZBTB20,SLC4A4,LPIN2,RFX4,NFIA,CTBP1,PRDM16
2.646e-02	-3.63	human chr6p24.2	chromosome location	human chr6p24.2	14	1	26134	50	ELOVL2
2.653e-02	-3.63	haematopoietic_neoplasm	COSMIC cancer mutations	haematopoietic_neoplasm	11082	39	16828	49	DGKB,NCKAP5,QKI,PREX2,MSI2,SLC4A4,NTRK2,SOX5,RFX4,SLC13A5,FKBP5,NPAS3,LPIN2,PTPRZ1,SLC39A12,SLC1A3,TNS3,SLC1A2,NHSL1,FARP1,CTNND2,EGF,GRK5,COL11A1,ITPK1,USP6NL,SORCS2,ITPR2,GPC5,NFIA,PRDM16,GRIP1,RORA,LRIG1,ELOVL2,SLC6A11,ADAM12,PREX1,FHOD3
2.656e-02	-3.63	glycosaminoglycan binding	molecular function	GO:0005539	243	3	18094	48	FGFRL1,PTN,COL11A1
2.668e-02	-3.62	Diacylglycerol_kin_accessory	interpro domains	IPR000756	10	1	18521	50	DGKB
2.668e-02	-3.62	MIR_motif	interpro domains	IPR016093	10	1	18521	50	ITPR2
2.668e-02	-3.62	HCO3_transpt_euk	interpro domains	IPR003020	10	1	18521	50	SLC4A4
2.668e-02	-3.62	HCO3_transpt-like_TM_dom	interpro domains	IPR011531	10	1	18521	50	SLC4A4
2.668e-02	-3.62	MIP_CS	interpro domains	IPR022357	10	1	18521	50	AQP4
2.668e-02	-3.62	PAS_fold_3	interpro domains	IPR013655	10	1	18521	50	NPAS3
2.668e-02	-3.62	MIR_dom_sf	interpro domains	IPR036300	10	1	18521	50	ITPR2
2.668e-02	-3.62	DGK	interpro domains	IPR037607	10	1	18521	50	DGKB
2.668e-02	-3.62	PTrfase/Anion_transptr	interpro domains	IPR016152	10	1	18521	50	SLC4A4
2.679e-02	-3.62	FBXL19 (F-box and leucine rich repeat protein 19)	protein interactions	54620	101	2	19454	49	CTBP1,COL11A1
2.688e-02	-3.62	breast-carcinoma	COSMIC cancer mutations	breast-carcinoma	15030	48	16828	49	GPC5,USP6NL,SORCS2,APOA1,SLC1A3,FARP1,SLC1A2,NHSL1,CTNND2,FHOD3,CTBP1,LRIG1,ELOVL2,SLC6A11,ADAM12,GRIP1,RORA,AQP4,GPM6B,ZBTB20,PREX2,NCKAP5,DGKB,QKI,PTN,NRCAM,PTPRZ1,LPIN2,FKBP5,TRPS1,RFX4,ITPR2,GRK5,COL11A1,ITPK1,SNTB1,EGF,TNS3,PREX1,FGFRL1,PRDM16,NFIA,NTRK2,SLC4A4,SLC39A12,SLC13A5,NPAS3,SOX5
2.706e-02	-3.61	pseudomyxoma_peritonei	COSMIC cancer mutations	pseudomyxoma_peritonei	585	5	16828	49	NCKAP5,FARP1,COL11A1,TRPS1,TNS3
2.706e-02	-3.61	peritoneum-appendix-other-pseudomyxoma_peritonei	COSMIC cancer mutations	peritoneum-appendix-other-pseudomyxoma_peritonei	585	5	16828	49	NCKAP5,TRPS1,TNS3,FARP1,COL11A1
2.714e-02	-3.61	cellular response to brain-derived neurotrophic factor stimulus	biological process	GO:1990416	10	1	18204	50	NTRK2
2.714e-02	-3.61	high-density lipoprotein particle assembly	biological process	GO:0034380	10	1	18204	50	APOA1
2.714e-02	-3.61	positive regulation of receptor clustering	biological process	GO:1903911	10	1	18204	50	FARP1
2.714e-02	-3.61	protein oxidation	biological process	GO:0018158	10	1	18204	50	APOA1
2.714e-02	-3.61	trans-synaptic signaling, modulating synaptic transmission	biological process	GO:0099550	10	1	18204	50	NTRK2
2.714e-02	-3.61	alpha-linolenic acid metabolic process	biological process	GO:0036109	10	1	18204	50	ELOVL2
2.714e-02	-3.61	neurotransmitter receptor transport, endosome to postsynaptic membrane	biological process	GO:0098887	10	1	18204	50	GRIP1
2.714e-02	-3.61	regulation of mesenchymal stem cell differentiation	biological process	GO:2000739	10	1	18204	50	SOX5
2.714e-02	-3.61	neurotransmitter receptor transport, endosome to plasma membrane	biological process	GO:0099639	10	1	18204	50	GRIP1
2.714e-02	-3.61	regulation of intestinal lipid absorption	biological process	GO:1904729	10	1	18204	50	APOA1
2.714e-02	-3.61	positive regulation of hepatocyte proliferation	biological process	GO:2000347	10	1	18204	50	PTN
2.714e-02	-3.61	otolith development	biological process	GO:0048840	10	1	18204	50	LRIG1
2.714e-02	-3.61	regulation of CoA-transferase activity	biological process	GO:1905918	10	1	18204	50	APOA1
2.714e-02	-3.61	retinal rod cell development	biological process	GO:0046548	10	1	18204	50	NTRK2
2.723e-02	-3.60	appendix	COSMIC cancer mutations	appendix	586	5	16828	49	NCKAP5,COL11A1,FARP1,TNS3,TRPS1
2.728e-02	-3.60	FNTB (farnesyltransferase, CAAX box, subunit beta)	protein interactions	2342	102	2	19454	49	LPIN2,GRIP1
2.728e-02	-3.60	MIR7-1 (microRNA 7-1)	protein interactions	407043	102	2	19454	49	MSI2,QKI
2.731e-02	-3.60	Helical hairpin bin	gene3d domains	1.10.287.570	10	1	14470	40	SLC4A4
2.737e-02	-3.60	Gtf2e2 (general transcription factor II E, polypeptide 2 (beta subunit))	protein interactions	68153	11	1	19454	49	NHSL1
2.737e-02	-3.60	IRAG1 (inositol 1,4,5-triphosphate receptor associated 1)	protein interactions	10335	11	1	19454	49	ITPR2
2.737e-02	-3.60	GAL3ST1 (galactose-3-O-sulfotransferase 1)	protein interactions	9514	11	1	19454	49	LRIG1
2.737e-02	-3.60	DAZ1 (deleted in azoospermia 1)	protein interactions	1617	11	1	19454	49	QKI
2.737e-02	-3.60	EVA1A (eva-1 homolog A, regulator of programmed cell death)	protein interactions	84141	11	1	19454	49	PTN
2.737e-02	-3.60	LCORL (ligand dependent nuclear receptor corepressor like)	protein interactions	254251	11	1	19454	49	CTBP1
2.737e-02	-3.60	IL7 (interleukin 7)	protein interactions	3574	11	1	19454	49	QKI
2.737e-02	-3.60	ABCA13 (ATP binding cassette subfamily A member 13)	protein interactions	154664	11	1	19454	49	APOA1
2.741e-02	-3.60	uveal_tract	COSMIC cancer mutations	uveal_tract	587	5	16828	49	PREX2,GRK5,CTNND2,PREX1,FGFRL1
2.741e-02	-3.60	peritoneum	COSMIC cancer mutations	peritoneum	587	5	16828	49	FARP1,COL11A1,TNS3,TRPS1,NCKAP5
2.775e-02	-3.58	HCO3_cotransp	pfam domains	PF00955	10	1	17795	50	SLC4A4
2.775e-02	-3.58	PAS_3	pfam domains	PF08447	10	1	17795	50	NPAS3
2.775e-02	-3.58	DAGK_acc	pfam domains	PF00609	10	1	17795	50	DGKB
2.775e-02	-3.58	MIR	pfam domains	PF02815	10	1	17795	50	ITPR2
2.786e-02	-3.58	perisynaptic extracellular matrix	cellular component	GO:0098966	11	1	19108	49	PTPRZ1
2.786e-02	-3.58	platelet dense tubular network	cellular component	GO:0031094	11	1	19108	49	ITPR2
2.789e-02	-3.58	DAD	prosite domains	PS51231	8	1	12186	43	FHOD3
2.789e-02	-3.58	GATA_ZN_FINGER_1	prosite domains	PS00344	8	1	12186	43	TRPS1
2.789e-02	-3.58	C2_TENSIN	prosite domains	PS51182	8	1	12186	43	TNS3
2.789e-02	-3.58	PPASE_TENSIN	prosite domains	PS51181	8	1	12186	43	TNS3
2.802e-02	-3.58	RNA polymerase II transcription regulatory region sequence-specific DNA binding	molecular function	GO:0000977	1385	8	18094	48	NFIA,SOX5,PRDM16,ZBTB20,RFX4,TRPS1,NPAS3,RORA
2.828e-02	-3.57	MYCBP (MYC binding protein)	protein interactions	26292	104	2	19454	49	PREX1,PTN
2.832e-02	-3.56	human chr8q24.12	chromosome location	human chr8q24.12	15	1	26134	50	SNTB1
2.845e-02	-3.56	protein domain specific binding	molecular function	GO:0019904	651	5	18094	48	QKI,ADAM12,CTBP1,SNTB1,TRPS1
2.846e-02	-3.56	PTEN_C2	smart domains	SM01326	8	1	9717	35	TNS3
2.846e-02	-3.56	PKD	smart domains	SM00089	8	1	9717	35	SORCS2
2.849e-02	-3.56	transcription regulator activity	molecular function	GO:0140110	1937	10	18094	48	PRDM16,SOX5,NFIA,RFX4,ZBTB20,TRPS1,NPAS3,RORA,LPIN2,CTBP1
2.862e-02	-3.55	integrin-mediated signaling pathway	biological process	GO:0007229	96	2	18204	50	APOA1,PTN
2.865e-02	-3.55	urinary_tract-bladder-carcinoma	COSMIC cancer mutations	urinary_tract-bladder-carcinoma	14050	46	16828	49	RFX4,SOX5,TRPS1,NPAS3,SLC13A5,FKBP5,LPIN2,SLC39A12,PTPRZ1,NRCAM,PTN,QKI,NCKAP5,DGKB,SLC4A4,MSI2,PREX2,ZBTB20,NTRK2,GPM6B,NFIA,RORA,PRDM16,GRIP1,ADAM12,SLC6A11,LRIG1,ELOVL2,CTBP1,FHOD3,FGFRL1,PREX1,CTNND2,SLC1A2,FARP1,TNS3,SLC1A3,EGF,SNTB1,ITPK1,USP6NL,SORCS2,COL11A1,GRK5,GPC5,ITPR2
2.865e-02	-3.55	soft_tissue-striated_muscle-rhabdomyosarcoma	COSMIC cancer mutations	soft_tissue-striated_muscle-rhabdomyosarcoma	594	5	16828	49	CTNND2,PREX2,TRPS1,DGKB,PRDM16
2.868e-02	-3.55	molecular function activator activity	molecular function	GO:0140677	1132	7	18094	48	EGF,PTN,USP6NL,PREX1,ADGRB3,PREX2,APOA1
2.875e-02	-3.55	skin-back-malignant_melanoma-nodular	COSMIC cancer mutations	skin-back-malignant_melanoma-nodular	10	1	16828	49	PREX2
2.875e-02	-3.55	chiasm	COSMIC cancer mutations	chiasm	10	1	16828	49	QKI
2.880e-02	-3.55	Synthesis of pyrophosphates in the cytosol	REACTOME pathways	R-HSA-1855167	10	1	10285	30	ITPK1
2.880e-02	-3.55	Linoleic acid (LA) metabolism	REACTOME pathways	R-HSA-2046105	10	1	10285	30	ELOVL2
2.880e-02	-3.55	Bicarbonate transporters	REACTOME pathways	R-HSA-425381	10	1	10285	30	SLC4A4
2.880e-02	-3.55	ATP-dependent diacylglycerol kinase activity	molecular function	GO:0004143	11	1	18094	48	DGKB
2.880e-02	-3.55	sulfur amino acid transmembrane transporter activity	molecular function	GO:0000099	11	1	18094	48	SLC1A2
2.880e-02	-3.55	structural constituent of myelin sheath	molecular function	GO:0019911	11	1	18094	48	GPM6B
2.880e-02	-3.55	inositol phosphate kinase activity	molecular function	GO:0180030	11	1	18094	48	ITPK1
2.881e-02	-3.55	transport	biological process	GO:0006810	3615	16	18204	50	SLC1A2,AQP4,QKI,SLC4A4,APOA1,ITPR2,SLC6A11,USP6NL,GRIP1,GPM6B,SORCS2,NTRK2,SLC13A5,SLC1A3,SLC39A12,CTBP1
2.894e-02	-3.54	Ig-like_dom	interpro domains	IPR007110	432	4	18521	50	FGFRL1,NRCAM,LRIG1,NTRK2
2.907e-02	-3.54	viral process	biological process	GO:0016032	243	3	18204	50	CTBP1,NFIA,USP6NL
2.917e-02	-3.53	nerve development	biological process	GO:0021675	97	2	18204	50	LRIG1,SLC1A3
2.917e-02	-3.53	acylglycerol metabolic process	biological process	GO:0006639	97	2	18204	50	LPIN2,DGKB
2.929e-02	-3.53	PTN (pleiotrophin)	protein interactions	5764	106	2	19454	49	PTN,PTPRZ1
2.931e-02	-3.53	Tyr_kinase_rcpt_2_CS	interpro domains	IPR002011	11	1	18521	50	NTRK2
2.931e-02	-3.53	GBD/FH3_dom	interpro domains	IPR014768	11	1	18521	50	FHOD3
2.931e-02	-3.53	PKD_dom	interpro domains	IPR000601	11	1	18521	50	SORCS2
2.931e-02	-3.53	Fib_collagen_C	interpro domains	IPR000885	11	1	18521	50	COL11A1
2.931e-02	-3.53	PKD_dom_sf	interpro domains	IPR035986	11	1	18521	50	SORCS2
2.931e-02	-3.53	GAIN_dom_N	interpro domains	IPR032471	11	1	18521	50	ADGRB3
2.941e-02	-3.53	Gap junction	KEGG pathways	ko04540	88	2	7161	22	ITPR2,EGF
2.941e-02	-3.53	Gap junction	KEGG pathways	hsa04540	88	2	7161	22	ITPR2,EGF
2.941e-02	-3.53	molecular adaptor activity	molecular function	GO:0060090	1138	7	18094	48	PRDM16,COL11A1,FKBP5,GRIP1,QKI,LPIN2,CTBP1
2.971e-02	-3.52	response to abiotic stimulus	biological process	GO:0009628	1100	7	18204	50	COL11A1,ITPR2,SLC1A3,SLC39A12,RORA,PTN,SLC1A2
2.972e-02	-3.52	neutral lipid metabolic process	biological process	GO:0006638	98	2	18204	50	DGKB,LPIN2
2.980e-02	-3.51	CHMP2A (charged multivesicular body protein 2A)	protein interactions	27243	107	2	19454	49	MSI2,FKBP5
2.981e-02	-3.51	lipid phosphorylation	biological process	GO:0046834	11	1	18204	50	DGKB
2.981e-02	-3.51	negative regulation of heterotypic cell-cell adhesion	biological process	GO:0034115	11	1	18204	50	APOA1
2.981e-02	-3.51	dendrite arborization	biological process	GO:0140059	11	1	18204	50	PTN
2.981e-02	-3.51	synaptic vesicle clustering	biological process	GO:0097091	11	1	18204	50	CTBP1
2.981e-02	-3.51	regulation of cell-cell adhesion involved in gastrulation	biological process	GO:0070587	11	1	18204	50	APOA1
2.981e-02	-3.51	intracellular mRNA localization	biological process	GO:0008298	11	1	18204	50	QKI
2.981e-02	-3.51	peptidyl-methionine modification	biological process	GO:0018206	11	1	18204	50	APOA1
2.981e-02	-3.51	glutamate secretion	biological process	GO:0014047	11	1	18204	50	NTRK2
2.982e-02	-3.51	Pcbp2 (poly(rC) binding protein 2)	protein interactions	18521	12	1	19454	49	FARP1
2.982e-02	-3.51	XDH (xanthine dehydrogenase)	protein interactions	7498	12	1	19454	49	GRIP1
2.982e-02	-3.51	NTF4 (neurotrophin 4)	protein interactions	4909	12	1	19454	49	NTRK2
2.982e-02	-3.51	IL15 (interleukin 15)	protein interactions	3600	12	1	19454	49	LRIG1
2.982e-02	-3.51	TREM2 (triggering receptor expressed on myeloid cells 2)	protein interactions	54209	12	1	19454	49	APOA1
2.982e-02	-3.51	CA4 (carbonic anhydrase 4)	protein interactions	762	12	1	19454	49	SLC4A4
2.990e-02	-3.51	response to xenobiotic stimulus	biological process	GO:0009410	429	4	18204	50	SLC1A3,SLC1A2,SLC6A11,RORA
2.992e-02	-3.51	MCM6 (minichromosome maintenance complex component 6)	protein interactions	4175	268	3	19454	49	PRDM16,TRPS1,FKBP5
2.993e-02	-3.51	astrocytoma_Grade_II	COSMIC cancer mutations	astrocytoma_Grade_II	601	5	16828	49	FARP1,COL11A1,PREX2,ZBTB20,PREX1
3.016e-02	-3.50	SNCA (synuclein alpha)	protein interactions	6622	696	5	19454	49	NTRK2,GRIP1,FARP1,APOA1,GRK5
3.018e-02	-3.50	human chr7p12.3	chromosome location	human chr7p12.3	16	1	26134	50	TNS3
3.031e-02	-3.50	PAX8 (paired box 8)	protein interactions	7849	108	2	19454	49	NFIA,TRPS1
3.031e-02	-3.50	FKBP1A (FKBP prolyl isomerase 1A)	protein interactions	2280	108	2	19454	49	CTBP1,MSI2
3.031e-02	-3.50	EN1 (engrailed homeobox 1)	protein interactions	2019	108	2	19454	49	NFIA,TRPS1
3.031e-02	-3.50	CAMKV (CaM kinase like vesicle associated)	protein interactions	79012	108	2	19454	49	FARP1,FKBP5
3.034e-02	-3.50	trans-synaptic signaling	biological process	GO:0099537	431	4	18204	50	NTRK2,SLC1A2,SLC1A3,FARP1
3.035e-02	-3.49	fibrillar collagen trimer	cellular component	GO:0005583	12	1	19108	49	COL11A1
3.035e-02	-3.49	synapse-associated extracellular matrix	cellular component	GO:0099535	12	1	19108	49	PTPRZ1
3.035e-02	-3.49	banded collagen fibril	cellular component	GO:0098643	12	1	19108	49	COL11A1
3.039e-02	-3.49	skin-hand-carcinoma-squamous_cell_carcinoma	COSMIC cancer mutations	skin-hand-carcinoma-squamous_cell_carcinoma	407	4	16828	49	SLC4A4,FARP1,PREX1,SLC13A5
3.044e-02	-3.49	Prot-tyrosine_phosphatase-like	interpro domains	IPR029021	101	2	18521	50	TNS3,PTPRZ1
3.049e-02	-3.49	LRRCT	pfam domains	PF01463	11	1	17795	50	LRIG1
3.049e-02	-3.49	COLFI	pfam domains	PF01410	11	1	17795	50	COL11A1
3.049e-02	-3.49	GAIN	pfam domains	PF16489	11	1	17795	50	ADGRB3
3.063e-02	-3.49	spleen	COSMIC cancer mutations	spleen	408	4	16828	49	SLC6A11,COL11A1,PTPRZ1,FHOD3
3.079e-02	-3.48	positive regulation of catalytic activity	biological process	GO:0043085	868	6	18204	50	EGF,APOA1,NTRK2,PREX2,USP6NL,PREX1
3.083e-02	-3.48	MIR34B (microRNA 34b)	protein interactions	407041	109	2	19454	49	MSI2,QKI
3.085e-02	-3.48	response to alkaloid	biological process	GO:0043279	100	2	18204	50	SLC1A3,SLC1A2
3.087e-02	-3.48	eye	COSMIC cancer mutations	eye	606	5	16828	49	PREX2,GRK5,CTNND2,PREX1,FGFRL1
3.104e-02	-3.47	regulation of cellular component organization	biological process	GO:0051128	2455	12	18204	50	ADGRB3,EGF,APOA1,FARP1,PREX1,USP6NL,GRIP1,PTN,GPM6B,NTRK2,NRCAM,SLC39A12
3.132e-02	-3.46	RFX_DBD	prosite domains	PS51526	9	1	12186	43	RFX4
3.138e-02	-3.46	protein binding involved in heterotypic cell-cell adhesion	molecular function	GO:0086080	12	1	18094	48	NRCAM
3.138e-02	-3.46	macrolide binding	molecular function	GO:0005527	12	1	18094	48	FKBP5
3.138e-02	-3.46	inositol 1,4,5 trisphosphate binding	molecular function	GO:0070679	12	1	18094	48	ITPR2
3.142e-02	-3.46	cholesterol homeostasis	biological process	GO:0042632	101	2	18204	50	RORA,APOA1
3.158e-02	-3.46	skin-back-malignant_melanoma-superficial_spreading	COSMIC cancer mutations	skin-back-malignant_melanoma-superficial_spreading	11	1	16828	49	PREX2
3.158e-02	-3.46	skin-hand-malignant_melanoma-acral_lentiginous	COSMIC cancer mutations	skin-hand-malignant_melanoma-acral_lentiginous	11	1	16828	49	PREX2
3.164e-02	-3.45	Creatine metabolism	REACTOME pathways	R-HSA-71288	11	1	10285	30	SLC6A11
3.179e-02	-3.45	NAD+ Signalling and Aging	SMPDB pathways	SMP0084271	11	1	1369	4	RORA
3.188e-02	-3.45	HYPK (huntingtin interacting protein K)	protein interactions	25764	111	2	19454	49	APOA1,QKI
3.193e-02	-3.44	MAD_homology1_Dwarfin-type	interpro domains	IPR003619	12	1	18521	50	NFIA
3.199e-02	-3.44	sterol homeostasis	biological process	GO:0055092	102	2	18204	50	RORA,APOA1
3.204e-02	-3.44	human chr9q21.33	chromosome location	human chr9q21.33	17	1	26134	50	NTRK2
3.207e-02	-3.44	bile_duct	COSMIC cancer mutations	bile_duct	15095	48	16828	49	ITPR2,GRK5,ITPK1,COL11A1,SNTB1,EGF,TNS3,PREX1,FGFRL1,PRDM16,NFIA,NTRK2,SLC4A4,SLC39A12,NPAS3,SLC13A5,SOX5,GPC5,SORCS2,USP6NL,APOA1,SLC1A3,CTNND2,FARP1,NHSL1,SLC1A2,CTBP1,FHOD3,SLC6A11,LRIG1,ELOVL2,ADAM12,GRIP1,RORA,GPM6B,AQP4,ZBTB20,MSI2,PREX2,DGKB,QKI,PTN,NRCAM,PTPRZ1,LPIN2,FKBP5,TRPS1,RFX4
3.207e-02	-3.44	biliary_tract-bile_duct-carcinoma-adenocarcinoma	COSMIC cancer mutations	biliary_tract-bile_duct-carcinoma-adenocarcinoma	15095	48	16828	49	FKBP5,RFX4,TRPS1,PTPRZ1,LPIN2,QKI,DGKB,NRCAM,PTN,ZBTB20,MSI2,PREX2,RORA,GRIP1,GPM6B,AQP4,CTBP1,FHOD3,ADAM12,SLC6A11,LRIG1,ELOVL2,APOA1,CTNND2,FARP1,SLC1A2,NHSL1,SLC1A3,GPC5,USP6NL,SORCS2,NPAS3,SLC13A5,SOX5,SLC39A12,NTRK2,SLC4A4,PRDM16,NFIA,FGFRL1,PREX1,EGF,SNTB1,TNS3,ITPR2,ITPK1,COL11A1,GRK5
3.208e-02	-3.44	HCO3TRNSPORT	prints domains	PR01231	10	1	5227	17	SLC4A4
3.226e-02	-3.43	NCAN (neurocan)	protein interactions	1463	13	1	19454	49	PTN
3.226e-02	-3.43	PCDHB5 (protocadherin beta 5)	protein interactions	26167	13	1	19454	49	DGKB
3.226e-02	-3.43	CD40LG (CD40 ligand)	protein interactions	959	13	1	19454	49	APOA1
3.226e-02	-3.43	PRRX1 (paired related homeobox 1)	protein interactions	5396	13	1	19454	49	FKBP5
3.226e-02	-3.43	CACNB4 (calcium voltage-gated channel auxiliary subunit beta 4)	protein interactions	785	13	1	19454	49	PTN
3.226e-02	-3.43	DNTT (DNA nucleotidylexotransferase)	protein interactions	1791	13	1	19454	49	APOA1
3.226e-02	-3.43	Rbm47 (RNA binding motif protein 47)	protein interactions	245945	13	1	19454	49	QKI
3.226e-02	-3.43	NOL4L (nucleolar protein 4 like)	protein interactions	140688	13	1	19454	49	CTBP1
3.226e-02	-3.43	CABP1 (calcium binding protein 1)	protein interactions	9478	13	1	19454	49	GRK5
3.226e-02	-3.43	PCDHA2 (protocadherin alpha 2)	protein interactions	56146	13	1	19454	49	NFIA
3.226e-02	-3.43	PLEKHH1 (pleckstrin homology, MyTH4 and FERM domain containing H1)	protein interactions	57475	13	1	19454	49	FKBP5
3.226e-02	-3.43	PSD2 (pleckstrin and Sec7 domain containing 2)	protein interactions	84249	13	1	19454	49	FARP1
3.245e-02	-3.43	skin-knee-malignant_melanoma	COSMIC cancer mutations	skin-knee-malignant_melanoma	97	2	16828	49	ADAM12,SLC6A11
3.248e-02	-3.43	negative regulation of neuroblast proliferation	biological process	GO:0007406	12	1	18204	50	PTN
3.248e-02	-3.43	neuronal ion channel clustering	biological process	GO:0045161	12	1	18204	50	NRCAM
3.248e-02	-3.43	positive regulation of protein localization to endosome	biological process	GO:1905668	12	1	18204	50	EGF
3.248e-02	-3.43	negative regulation of protein localization to cell surface	biological process	GO:2000009	12	1	18204	50	GPM6B
3.248e-02	-3.43	auditory behavior	biological process	GO:0031223	12	1	18204	50	SLC1A3
3.248e-02	-3.43	microglia differentiation	biological process	GO:0014004	12	1	18204	50	QKI
3.248e-02	-3.43	regulation of intestinal absorption	biological process	GO:1904478	12	1	18204	50	APOA1
3.248e-02	-3.43	sulfur amino acid transport	biological process	GO:0000101	12	1	18204	50	SLC1A2
3.250e-02	-3.43	DNA-binding transcription repressor activity, RNA polymerase II-specific	molecular function	GO:0001227	263	3	18094	48	ZBTB20,PRDM16,TRPS1
3.257e-02	-3.42	regulation of biomineral tissue development	biological process	GO:0070167	103	2	18204	50	PTN,GPM6B
3.276e-02	-3.42	steroid binding	molecular function	GO:0005496	107	2	18094	48	RORA,APOA1
3.284e-02	-3.42	chylomicron	cellular component	GO:0042627	13	1	19108	49	APOA1
3.294e-02	-3.41	SATB1 (SATB homeobox 1)	protein interactions	6304	113	2	19454	49	SOX5,CTBP1
3.300e-02	-3.41	1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)	BIOCYC pathways	META_PWY-6362	15	1	902	2	ITPK1
3.300e-02	-3.41	1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)	BIOCYC pathways	HUMAN_PWY-6362	15	1	902	2	ITPK1
3.306e-02	-3.41	bone-tibia-other-chondroblastoma	COSMIC cancer mutations	bone-tibia-other-chondroblastoma	98	2	16828	49	NCKAP5,CTNND2
3.310e-02	-3.41	urinary_tract	COSMIC cancer mutations	urinary_tract	14112	46	16828	49	SNTB1,EGF,SLC1A3,TNS3,SLC1A2,FARP1,CTNND2,ITPR2,GPC5,GRK5,COL11A1,SORCS2,USP6NL,ITPK1,PRDM16,GRIP1,RORA,NFIA,GPM6B,PREX1,FGFRL1,FHOD3,CTBP1,ELOVL2,LRIG1,SLC6A11,ADAM12,DGKB,NCKAP5,QKI,NRCAM,PTN,NTRK2,ZBTB20,PREX2,MSI2,SLC4A4,FKBP5,SLC13A5,NPAS3,SOX5,TRPS1,RFX4,PTPRZ1,SLC39A12,LPIN2
3.310e-02	-3.41	bladder	COSMIC cancer mutations	bladder	14112	46	16828	49	PTN,NRCAM,NCKAP5,DGKB,QKI,PREX2,MSI2,ZBTB20,TRPS1,RFX4,FKBP5,LPIN2,PTPRZ1,SLC1A3,FARP1,SLC1A2,CTNND2,USP6NL,SORCS2,GPC5,GPM6B,GRIP1,RORA,ELOVL2,LRIG1,SLC6A11,ADAM12,FHOD3,CTBP1,SLC4A4,NTRK2,SOX5,SLC13A5,NPAS3,SLC39A12,TNS3,SNTB1,EGF,GRK5,COL11A1,ITPK1,ITPR2,NFIA,PRDM16,PREX1,FGFRL1
3.315e-02	-3.41	regulation of steroid metabolic process	biological process	GO:0019218	104	2	18204	50	APOA1,RORA
3.321e-02	-3.40	MH1	pfam domains	PF03165	12	1	17795	50	NFIA
3.347e-02	-3.40	LSM3 (LSM3 homolog, U6 small nuclear RNA and mRNA degradation associated)	protein interactions	27258	114	2	19454	49	FARP1,QKI
3.352e-02	-3.40	tibia	COSMIC cancer mutations	tibia	836	6	16828	49	NCKAP5,QKI,PREX2,CTNND2,ADAM12,USP6NL
3.369e-02	-3.39	PRKACA (protein kinase cAMP-activated catalytic subunit alpha)	protein interactions	5566	486	4	19454	49	SNTB1,SLC4A4,FKBP5,ITPR2
3.373e-02	-3.39	inner ear morphogenesis	biological process	GO:0042472	105	2	18204	50	LRIG1,COL11A1
3.386e-02	-3.39	Glycerophospholipid metabolism	KEGG pathways	ko00564	95	2	7161	22	DGKB,LPIN2
3.386e-02	-3.39	Pancreatic secretion	KEGG pathways	ko04972	95	2	7161	22	SLC4A4,ITPR2
3.386e-02	-3.39	Pancreatic secretion	KEGG pathways	hsa04972	95	2	7161	22	SLC4A4,ITPR2
3.386e-02	-3.39	Glycerophospholipid metabolism	KEGG pathways	hsa00564	95	2	7161	22	LPIN2,DGKB
3.389e-02	-3.38	human chr12q14.3	chromosome location	human chr12q14.3	18	1	26134	50	GRIP1
3.389e-02	-3.38	human chr7q31.32	chromosome location	human chr7q31.32	18	1	26134	50	PTPRZ1
3.390e-02	-3.38	RCOR1 (REST corepressor 1)	protein interactions	23186	487	4	19454	49	CTBP1,SOX5,TRPS1,PRDM16
3.395e-02	-3.38	high-density lipoprotein particle binding	molecular function	GO:0008035	13	1	18094	48	APOA1
3.395e-02	-3.38	histone H3K9 methyltransferase activity	molecular function	GO:0046974	13	1	18094	48	PRDM16
3.401e-02	-3.38	TBXT (T-box transcription factor T)	protein interactions	6862	115	2	19454	49	TRPS1,NFIA
3.401e-02	-3.38	DTNA (dystrobrevin alpha)	protein interactions	1837	115	2	19454	49	SNTB1,NTRK2
3.415e-02	-3.38	FTO Obesity Variant Mechanism	WikiPathways	WP3407	8	1	5310	23	PRDM16
3.425e-02	-3.37	Hemostasis	REACTOME pathways	R-HSA-109582	632	5	10285	30	EGF,ITPK1,DGKB,ITPR2,APOA1
3.425e-02	-3.37	signal transduction	biological process	GO:0007165	4637	19	18204	50	SORCS2,NTRK2,SLC39A12,PREX1,GRIP1,GRK5,PTN,NFIA,ITPK1,DGKB,EGF,APOA1,ITPR2,FARP1,ADGRB3,CTNND2,FGFRL1,PREX2,RORA
3.439e-02	-3.37	ear	COSMIC cancer mutations	ear	624	5	16828	49	ZBTB20,NPAS3,FGFRL1,SLC6A11,GRK5
3.440e-02	-3.37	central_nervous_system-fourth_ventricle-glioma-astrocytoma_Grade_I	COSMIC cancer mutations	central_nervous_system-fourth_ventricle-glioma-astrocytoma_Grade_I	12	1	16828	49	QKI
3.440e-02	-3.37	skin-abdomen-malignant_melanoma-nodular	COSMIC cancer mutations	skin-abdomen-malignant_melanoma-nodular	12	1	16828	49	PREX2
3.440e-02	-3.37	DNA-binding transcription factor activity	molecular function	GO:0003700	1441	8	18094	48	RORA,NPAS3,TRPS1,ZBTB20,RFX4,SOX5,NFIA,PRDM16
3.446e-02	-3.37	Defective EXT1 causes exostoses 1, TRPS2 and CHDS	REACTOME pathways	R-HSA-3656253	12	1	10285	30	GPC5
3.446e-02	-3.37	Repression of WNT target genes	REACTOME pathways	R-HSA-4641265	12	1	10285	30	CTBP1
3.446e-02	-3.37	Defective EXT2 causes exostoses 2	REACTOME pathways	R-HSA-3656237	12	1	10285	30	GPC5
3.454e-02	-3.37	ATP-grasp	interpro domains	IPR011761	13	1	18521	50	ITPK1
3.454e-02	-3.37	FA	interpro domains	IPR014847	13	1	18521	50	FARP1
3.455e-02	-3.37	phosphotransferase activity, alcohol group as acceptor	molecular function	GO:0016773	686	5	18094	48	NTRK2,FGFRL1,ITPK1,DGKB,GRK5
3.470e-02	-3.36	DNAJC27 (DnaJ heat shock protein family (Hsp40) member C27)	protein interactions	51277	14	1	19454	49	FKBP5
3.470e-02	-3.36	DACT2 (dishevelled binding antagonist of beta catenin 2)	protein interactions	168002	14	1	19454	49	ZBTB20
3.470e-02	-3.36	TRAC (T cell receptor alpha constant)	protein interactions	28755	14	1	19454	49	ITPK1
3.470e-02	-3.36	ROBO3 (roundabout guidance receptor 3)	protein interactions	64221	14	1	19454	49	APOA1
3.470e-02	-3.36	SLC1A2 (solute carrier family 1 member 2)	protein interactions	6506	14	1	19454	49	SLC1A2
3.470e-02	-3.36	Cstf2t (cleavage stimulation factor, 3' pre-RNA subunit 2, tau)	protein interactions	83410	14	1	19454	49	CTBP1
3.474e-02	-3.36	MIP	prosite domains	PS00221	10	1	12186	43	AQP4
3.474e-02	-3.36	MIR	prosite domains	PS50919	10	1	12186	43	ITPR2
3.475e-02	-3.36	Visual phototransduction	REACTOME pathways	R-HSA-2187338	101	2	10285	30	GPC5,APOA1
3.485e-02	-3.36	regulation of anatomical structure morphogenesis	biological process	GO:0022603	894	6	18204	50	SLC39A12,EGF,NTRK2,GRIP1,ADGRB3,ADAM12
3.496e-02	-3.35	PPARG (peroxisome proliferator activated receptor gamma)	protein interactions	5468	285	3	19454	49	GRIP1,ZBTB20,TRPS1
3.501e-02	-3.35	large_intestine-colon-adenoma	COSMIC cancer mutations	large_intestine-colon-adenoma	627	5	16828	49	COL11A1,CTNND2,FHOD3,PREX1,NCKAP5
3.505e-02	-3.35	sulfur compound binding	molecular function	GO:1901681	271	3	18094	48	PTN,FGFRL1,COL11A1
3.505e-02	-3.35	transcription coactivator activity	molecular function	GO:0003713	271	3	18094	48	CTBP1,LPIN2,PRDM16
3.514e-02	-3.35	positive regulation of neuron projection regeneration	biological process	GO:0070572	13	1	18204	50	PTN
3.514e-02	-3.35	cerebellar Purkinje cell differentiation	biological process	GO:0021702	13	1	18204	50	RORA
3.514e-02	-3.35	heterochromatin organization	biological process	GO:0070828	13	1	18204	50	PRDM16
3.514e-02	-3.35	phospholipid efflux	biological process	GO:0033700	13	1	18204	50	APOA1
3.514e-02	-3.35	positive regulation of axon regeneration	biological process	GO:0048680	13	1	18204	50	PTN
3.514e-02	-3.35	glial cell fate commitment	biological process	GO:0021781	13	1	18204	50	NFIA
3.514e-02	-3.35	T-helper 17 cell differentiation	biological process	GO:0072539	13	1	18204	50	RORA
3.514e-02	-3.35	very long-chain fatty acid biosynthetic process	biological process	GO:0042761	13	1	18204	50	ELOVL2
3.514e-02	-3.35	regulation of protein localization to endosome	biological process	GO:1905666	13	1	18204	50	EGF
3.532e-02	-3.34	extrinsic component of synaptic membrane	cellular component	GO:0099243	14	1	19108	49	FARP1
3.533e-02	-3.34	TYR_PHOSPHATASE_2	prosite domains	PS50056	84	2	12186	43	PTPRZ1,TNS3
3.538e-02	-3.34	DNA-binding transcription repressor activity	molecular function	GO:0001217	272	3	18094	48	TRPS1,PRDM16,ZBTB20
3.538e-02	-3.34	phosphatase activity	molecular function	GO:0016791	272	3	18094	48	PTPRZ1,LPIN2,TNS3
3.546e-02	-3.34	DAGKa	smart domains	SM00045	10	1	9717	35	DGKB
3.546e-02	-3.34	MIR	smart domains	SM00472	10	1	9717	35	ITPR2
3.553e-02	-3.34	lung-carcinoma-adenocarcinoma	COSMIC cancer mutations	lung-carcinoma-adenocarcinoma	15133	48	16828	49	SLC13A5,NPAS3,SOX5,SLC39A12,NTRK2,SLC4A4,PRDM16,NFIA,PREX1,FGFRL1,SNTB1,EGF,TNS3,ITPR2,GRK5,COL11A1,ITPK1,FKBP5,TRPS1,RFX4,PTPRZ1,LPIN2,NCKAP5,DGKB,QKI,PTN,NRCAM,ZBTB20,PREX2,MSI2,GRIP1,RORA,AQP4,GPM6B,FHOD3,CTBP1,ELOVL2,LRIG1,SLC6A11,ADAM12,SLC1A3,FARP1,SLC1A2,NHSL1,CTNND2,GPC5,SORCS2,USP6NL
3.558e-02	-3.34	NAT10 (N-acetyltransferase 10)	protein interactions	55226	287	3	19454	49	PRDM16,GRK5,FKBP5
3.558e-02	-3.34	PARD3 (par-3 family cell polarity regulator)	protein interactions	56288	287	3	19454	49	FARP1,NTRK2,USP6NL
3.574e-02	-3.33	human chr6q24.1	chromosome location	human chr6q24.1	19	1	26134	50	NHSL1
3.574e-02	-3.33	human chr5p15.2	chromosome location	human chr5p15.2	19	1	26134	50	CTNND2
3.575e-02	-3.33	LRRCT	smart domains	SM00082	83	2	9717	35	NTRK2,LRIG1
3.585e-02	-3.33	Estrogen signaling pathway	KEGG pathways	hsa04915	98	2	7161	22	ITPR2,FKBP5
3.585e-02	-3.33	Estrogen signaling pathway	KEGG pathways	ko04915	98	2	7161	22	FKBP5,ITPR2
3.593e-02	-3.33	FA	pfam domains	PF08736	13	1	17795	50	FARP1
3.593e-02	-3.33	Ldl_recept_b	pfam domains	PF00058	13	1	17795	50	EGF
3.610e-02	-3.32	skin-trunk-malignant_melanoma	COSMIC cancer mutations	skin-trunk-malignant_melanoma	2647	13	16828	49	COL11A1,PREX2,CTNND2,SLC1A3,NRCAM,EGF,NCKAP5,SNTB1,DGKB,PTPRZ1,TRPS1,SOX5,PRDM16
3.612e-02	-3.32	long-chain fatty acid metabolic process	biological process	GO:0001676	109	2	18204	50	QKI,ELOVL2
3.612e-02	-3.32	postsynapse organization	biological process	GO:0099173	109	2	18204	50	FARP1,CTNND2
3.620e-02	-3.32	regulation of canonical Wnt signaling pathway	biological process	GO:0060828	265	3	18204	50	EGF,CTNND2,GPC5
3.620e-02	-3.32	ANKRD26 (ankyrin repeat domain containing 26)	protein interactions	22852	119	2	19454	49	NCKAP5,NTRK2
3.631e-02	-3.32	neuronal cell body	cellular component	GO:0043025	489	4	19108	49	SORCS2,CTNND2,GRIP1,SLC1A3
3.652e-02	-3.31	BCOR (BCL6 corepressor)	protein interactions	54880	290	3	19454	49	SOX5,NFIA,CTBP1
3.652e-02	-3.31	phosphatidate phosphatase activity	molecular function	GO:0008195	14	1	18094	48	LPIN2
3.652e-02	-3.31	Choline metabolism in cancer	KEGG pathways	hsa05231	99	2	7161	22	DGKB,EGF
3.652e-02	-3.31	Choline metabolism in cancer	KEGG pathways	ko05231	99	2	7161	22	DGKB,EGF
3.670e-02	-3.30	positive regulation of cell development	biological process	GO:0010720	458	4	18204	50	PTN,QKI,PTPRZ1,NTRK2
3.672e-02	-3.30	positive regulation of cell junction assembly	biological process	GO:1901890	110	2	18204	50	ADGRB3,NTRK2
3.672e-02	-3.30	positive regulation of canonical Wnt signaling pathway	biological process	GO:0090263	110	2	18204	50	EGF,GPC5
3.677e-02	-3.30	transcription coregulator binding	molecular function	GO:0001221	114	2	18094	48	CTBP1,RORA
3.684e-02	-3.30	positive regulation of cell differentiation	biological process	GO:0045597	906	6	18204	50	PTN,SOX5,PTPRZ1,QKI,NRCAM,NTRK2
3.695e-02	-3.30	small molecule biosynthetic process	biological process	GO:0044283	459	4	18204	50	ELOVL2,QKI,APOA1,SLC1A3
3.695e-02	-3.30	synaptic signaling	biological process	GO:0099536	459	4	18204	50	SLC1A2,SLC1A3,NTRK2,FARP1
3.714e-02	-3.29	Cenpf (centromere protein F)	protein interactions	108000	15	1	19454	49	USP6NL
3.714e-02	-3.29	TESPA1 (thymocyte expressed, positive selection associated 1)	protein interactions	9840	15	1	19454	49	ITPR2
3.714e-02	-3.29	DTWD1 (DTW domain containing 1)	protein interactions	56986	15	1	19454	49	APOA1
3.714e-02	-3.29	GRM7 (glutamate metabotropic receptor 7)	protein interactions	2917	15	1	19454	49	GRIP1
3.715e-02	-3.29	MIP	interpro domains	IPR000425	14	1	18521	50	AQP4
3.715e-02	-3.29	LDLR_classB_rpt	interpro domains	IPR000033	14	1	18521	50	EGF
3.715e-02	-3.29	Aquaporin-like	interpro domains	IPR023271	14	1	18521	50	AQP4
3.715e-02	-3.29	ZIP	interpro domains	IPR003689	14	1	18521	50	SLC39A12
3.719e-02	-3.29	stomach-carcinoma-adenocarcinoma	COSMIC cancer mutations	stomach-carcinoma-adenocarcinoma	15150	48	16828	49	FGFRL1,PREX1,PRDM16,NFIA,ITPR2,ITPK1,COL11A1,GRK5,EGF,SNTB1,TNS3,SLC39A12,NPAS3,SLC13A5,SOX5,NTRK2,SLC4A4,CTBP1,FHOD3,ADAM12,SLC6A11,LRIG1,ELOVL2,RORA,GRIP1,GPM6B,AQP4,GPC5,SORCS2,USP6NL,APOA1,CTNND2,FARP1,SLC1A2,SLC1A3,PTPRZ1,LPIN2,FKBP5,RFX4,TRPS1,ZBTB20,MSI2,PREX2,QKI,DGKB,NCKAP5,PTN,NRCAM
3.721e-02	-3.29	skin-shoulder-malignant_melanoma-nodular	COSMIC cancer mutations	skin-shoulder-malignant_melanoma-nodular	13	1	16828	49	PREX2
3.721e-02	-3.29	central_nervous_system-hypothalamus-glioma-astrocytoma_Grade_I	COSMIC cancer mutations	central_nervous_system-hypothalamus-glioma-astrocytoma_Grade_I	13	1	16828	49	QKI
3.721e-02	-3.29	skin-scalp-malignant_melanoma-nodular	COSMIC cancer mutations	skin-scalp-malignant_melanoma-nodular	13	1	16828	49	PREX2
3.728e-02	-3.29	CLEC7A (Dectin-1) induces NFAT activation	REACTOME pathways	R-HSA-5607763	13	1	10285	30	ITPR2
3.728e-02	-3.29	Passive transport by Aquaporins	REACTOME pathways	R-HSA-432047	13	1	10285	30	AQP4
3.728e-02	-3.29	Scavenging of heme from plasma	REACTOME pathways	R-HSA-2168880	13	1	10285	30	APOA1
3.728e-02	-3.29	FGFRL1 modulation of FGFR1 signaling	REACTOME pathways	R-HSA-5658623	13	1	10285	30	FGFRL1
3.728e-02	-3.29	ERBB2 Activates PTK6 Signaling	REACTOME pathways	R-HSA-8847993	13	1	10285	30	EGF
3.729e-02	-3.29	soft_tissue-striated_muscle-rhabdomyosarcoma-embryonal	COSMIC cancer mutations	soft_tissue-striated_muscle-rhabdomyosarcoma-embryonal	2659	13	16828	49	SORCS2,GRK5,PREX2,DGKB,CTNND2,FGFRL1,PTPRZ1,ELOVL2,NPAS3,RORA,PRDM16,AQP4,NFIA
3.729e-02	-3.29	embryonal	COSMIC cancer mutations	embryonal	2659	13	16828	49	DGKB,PRDM16,NPAS3,RORA,CTNND2,AQP4,NFIA,PTPRZ1,FGFRL1,GRK5,ELOVL2,PREX2,SORCS2
3.732e-02	-3.29	MED15 (mediator complex subunit 15)	protein interactions	51586	121	2	19454	49	QKI,NFIA
3.754e-02	-3.28	basal plasma membrane	cellular component	GO:0009925	288	3	19108	49	AQP4,SLC4A4,SLC1A3
3.759e-02	-3.28	human chr18q12.2	chromosome location	human chr18q12.2	20	1	26134	50	FHOD3
3.779e-02	-3.28	negative regulation of cell adhesion molecule production	biological process	GO:0060354	14	1	18204	50	APOA1
3.779e-02	-3.28	cellular response to ethanol	biological process	GO:0071361	14	1	18204	50	ITPR2
3.779e-02	-3.28	fatty acid elongation	biological process	GO:0030497	14	1	18204	50	ELOVL2
3.779e-02	-3.28	glutathione biosynthetic process	biological process	GO:0006750	14	1	18204	50	SLC1A2
3.779e-02	-3.28	sodium ion export across plasma membrane	biological process	GO:0036376	14	1	18204	50	SLC4A4
3.779e-02	-3.28	cellular response to lithium ion	biological process	GO:0071285	14	1	18204	50	SLC13A5
3.779e-02	-3.28	negative regulation of long-term synaptic potentiation	biological process	GO:1900272	14	1	18204	50	PTN
3.779e-02	-3.28	mechanosensory behavior	biological process	GO:0007638	14	1	18204	50	SLC1A3
3.779e-02	-3.28	cerebrospinal fluid circulation	biological process	GO:0090660	14	1	18204	50	AQP4
3.779e-02	-3.28	neuron remodeling	biological process	GO:0016322	14	1	18204	50	ADGRB3
3.779e-02	-3.28	positive regulation of phospholipid transport	biological process	GO:2001140	14	1	18204	50	APOA1
3.779e-02	-3.28	neurotransmitter receptor transport to postsynaptic membrane	biological process	GO:0098969	14	1	18204	50	GRIP1
3.780e-02	-3.28	low-density lipoprotein particle	cellular component	GO:0034362	15	1	19108	49	APOA1
3.780e-02	-3.28	axolemma	cellular component	GO:0030673	15	1	19108	49	SLC1A2
3.788e-02	-3.27	AVPR2 (arginine vasopressin receptor 2)	protein interactions	554	122	2	19454	49	ELOVL2,GRK5
3.794e-02	-3.27	rhythmic process	biological process	GO:0048511	270	3	18204	50	NTRK2,RORA,PTN
3.795e-02	-3.27	Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds	REACTOME pathways	R-HSA-425366	106	2	10285	30	SLC13A5,SLC6A11
3.803e-02	-3.27	Glycerol uptake facilitator protein	gene3d domains	1.20.1080.10	14	1	14470	40	AQP4
3.803e-02	-3.27	-	gene3d domains	2.60.200.40	14	1	14470	40	DGKB
3.815e-02	-3.27	NC1_FIB	prosite domains	PS51461	11	1	12186	43	COL11A1
3.815e-02	-3.27	GBD_FH3	prosite domains	PS51232	11	1	12186	43	FHOD3
3.815e-02	-3.27	GATA_ZN_FINGER_2	prosite domains	PS50114	11	1	12186	43	TRPS1
3.815e-02	-3.27	RECEPTOR_TYR_KIN_II	prosite domains	PS00239	11	1	12186	43	NTRK2
3.815e-02	-3.27	PKD	prosite domains	PS50093	11	1	12186	43	SORCS2
3.822e-02	-3.26	cellular response to organic cyclic compound	biological process	GO:0071407	464	4	18204	50	RORA,SLC1A3,ITPR2,SLC1A2
3.829e-02	-3.26	carboxylic acid biosynthetic process	biological process	GO:0046394	271	3	18204	50	SLC1A3,ELOVL2,QKI
3.837e-02	-3.26	Gastrin-CREB signalling pathway via PKC and MAPK	REACTOME pathways	R-HSA-881907	443	4	10285	30	GRK5,ITPR2,DGKB,EGF
3.844e-02	-3.26	PAX7 (paired box 7)	protein interactions	5081	123	2	19454	49	NFIA,TRPS1
3.864e-02	-3.25	GATA	pfam domains	PF00320	14	1	17795	50	TRPS1
3.864e-02	-3.25	Zip	pfam domains	PF02535	14	1	17795	50	SLC39A12
3.864e-02	-3.25	MIP	pfam domains	PF00230	14	1	17795	50	AQP4
3.873e-02	-3.25	positive regulation of hydrolase activity	biological process	GO:0051345	466	4	18204	50	USP6NL,APOA1,PREX1,PREX2
3.894e-02	-3.25	COLFI	smart domains	SM00038	11	1	9717	35	COL11A1
3.900e-02	-3.24	vascular process in circulatory system	biological process	GO:0003018	273	3	18204	50	SLC4A4,SLC1A2,SLC1A3
3.901e-02	-3.24	HMGCR (3-hydroxy-3-methylglutaryl-CoA reductase)	protein interactions	3156	124	2	19454	49	CTBP1,SORCS2
3.908e-02	-3.24	C4-dicarboxylate transmembrane transporter activity	molecular function	GO:0015556	15	1	18094	48	SLC13A5
3.908e-02	-3.24	monocarboxylate:sodium symporter activity	molecular function	GO:0140161	15	1	18094	48	SLC6A11
3.924e-02	-3.24	Fatty acid biosynthesis, elongation, endoplasmic reticulum	KEGG pathways	M00415	13	1	7161	22	ELOVL2
3.924e-02	-3.24	Fatty acid biosynthesis, elongation, endoplasmic reticulum	KEGG pathways	hsa_M00415	13	1	7161	22	ELOVL2
3.936e-02	-3.24	organic acid biosynthetic process	biological process	GO:0016053	274	3	18204	50	SLC1A3,ELOVL2,QKI
3.943e-02	-3.23	human chr10q26.11	chromosome location	human chr10q26.11	21	1	26134	50	GRK5
3.943e-02	-3.23	human chr10q26.2	chromosome location	human chr10q26.2	21	1	26134	50	ADAM12
3.943e-02	-3.23	human chr13q31.3	chromosome location	human chr13q31.3	21	1	26134	50	GPC5
3.943e-02	-3.23	cell migration	biological process	GO:0016477	921	6	18204	50	APOA1,NRCAM,NTRK2,GPC5,PTN,PREX1
3.947e-02	-3.23	RAC1 (Rac family small GTPase 1)	protein interactions	5879	1005	6	19454	49	SLC1A3,FARP1,PREX1,PREX2,TNS3,USP6NL
3.947e-02	-3.23	pulmonary_blastoma	COSMIC cancer mutations	pulmonary_blastoma	648	5	16828	49	TRPS1,ADAM12,NCKAP5,FGFRL1,FHOD3
3.947e-02	-3.23	pleura-pulmonary_blastoma	COSMIC cancer mutations	pleura-pulmonary_blastoma	648	5	16828	49	FGFRL1,FHOD3,NCKAP5,ADAM12,TRPS1
3.956e-02	-3.23	import into cell	biological process	GO:0098657	687	5	18204	50	SLC1A2,SLC1A3,SLC39A12,SLC6A11,CTBP1
3.956e-02	-3.23	MKKS (MKKS centrosomal shuttling protein)	protein interactions	8195	16	1	19454	49	PTN
3.956e-02	-3.23	TXNDC2 (thioredoxin domain containing 2)	protein interactions	84203	16	1	19454	49	APOA1
3.956e-02	-3.23	MAML2 (mastermind like transcriptional coactivator 2)	protein interactions	84441	16	1	19454	49	CTBP1
3.956e-02	-3.23	HHV8GK18_gp78 (ORF69)	protein interactions	4961444	16	1	19454	49	CTBP1
3.956e-02	-3.23	TWIST2 (twist family bHLH transcription factor 2)	protein interactions	117581	16	1	19454	49	ZBTB20
3.956e-02	-3.23	NBL1 (NBL1, DAN family BMP antagonist)	protein interactions	4681	16	1	19454	49	LRIG1
3.956e-02	-3.23	PIPOX (pipecolic acid and sarcosine oxidase)	protein interactions	51268	16	1	19454	49	FKBP5
3.956e-02	-3.23	RHO (rhodopsin)	protein interactions	6010	16	1	19454	49	GRK5
3.956e-02	-3.23	ESM1 (endothelial cell specific molecule 1)	protein interactions	11082	16	1	19454	49	ADAM12
3.956e-02	-3.23	Sumo3 (small ubiquitin-like modifier 3)	protein interactions	20610	16	1	19454	49	ITPR2
3.963e-02	-3.23	lung-carcinoma-squamous_cell_carcinoma	COSMIC cancer mutations	lung-carcinoma-squamous_cell_carcinoma	14664	47	16828	49	ITPR2,GRK5,ITPK1,COL11A1,SNTB1,EGF,TNS3,PREX1,FGFRL1,PRDM16,NFIA,NTRK2,SLC4A4,SLC39A12,NPAS3,SLC13A5,SOX5,GPC5,SORCS2,USP6NL,SLC1A3,CTNND2,FARP1,NHSL1,SLC1A2,CTBP1,FHOD3,SLC6A11,LRIG1,ELOVL2,ADAM12,GRIP1,RORA,AQP4,ZBTB20,MSI2,PREX2,DGKB,NCKAP5,QKI,NRCAM,PTN,PTPRZ1,LPIN2,FKBP5,TRPS1,RFX4
3.975e-02	-3.23	PPIase_FKBP_dom	interpro domains	IPR001179	15	1	18521	50	FKBP5
3.975e-02	-3.23	Znf_GATA	interpro domains	IPR000679	15	1	18521	50	TRPS1
3.975e-02	-3.23	Diacylglycerol_kinase_cat_dom	interpro domains	IPR001206	15	1	18521	50	DGKB
3.975e-02	-3.23	FH2_Formin	interpro domains	IPR015425	15	1	18521	50	FHOD3
3.975e-02	-3.23	FH2_Formin_sf	interpro domains	IPR042201	15	1	18521	50	FHOD3
3.981e-02	-3.22	fatty acid biosynthetic process	biological process	GO:0006633	115	2	18204	50	ELOVL2,QKI
3.998e-02	-3.22	cellular homeostasis	biological process	GO:0019725	689	5	18204	50	SLC39A12,SLC1A3,AQP4,ZBTB20,SLC4A4
4.008e-02	-3.22	telencephalon development	biological process	GO:0021537	276	3	18204	50	SLC1A2,NTRK2,RFX4
4.008e-02	-3.22	sensory organ morphogenesis	biological process	GO:0090596	276	3	18204	50	COL11A1,NTRK2,LRIG1
4.008e-02	-3.22	transcription cis-regulatory region binding	molecular function	GO:0000976	1485	8	18094	48	RORA,NPAS3,TRPS1,RFX4,ZBTB20,PRDM16,SOX5,NFIA
4.010e-02	-3.22	Synthesis of PE	REACTOME pathways	R-HSA-1483213	14	1	10285	30	LPIN2
4.010e-02	-3.22	CDC42 (cell division cycle 42)	protein interactions	998	1280	7	19454	49	PREX2,USP6NL,ELOVL2,ITPR2,PREX1,SLC1A3,FARP1
4.016e-02	-3.21	CDK18 (cyclin dependent kinase 18)	protein interactions	5129	126	2	19454	49	FKBP5,TRPS1
4.027e-02	-3.21	asymmetric, glutamatergic, excitatory synapse	cellular component	GO:0098985	16	1	19108	49	ADGRB3
4.028e-02	-3.21	phospholipid binding	molecular function	GO:0005543	489	4	18094	48	ITPR2,GRK5,APOA1,PREX1
4.033e-02	-3.21	Inositol Phosphate Metabolism	SMPDB pathways	SMP0000462	14	1	1369	4	ITPK1
4.035e-02	-3.21	transcription regulatory region nucleic acid binding	molecular function	GO:0001067	1487	8	18094	48	RFX4,ZBTB20,SOX5,NFIA,PRDM16,RORA,TRPS1,NPAS3
4.043e-02	-3.21	regulation of phospholipid transport	biological process	GO:2001138	15	1	18204	50	APOA1
4.043e-02	-3.21	positive regulation of cholesterol metabolic process	biological process	GO:0090205	15	1	18204	50	APOA1
4.043e-02	-3.21	glucocorticoid metabolic process	biological process	GO:0008211	15	1	18204	50	APOA1
4.043e-02	-3.21	regulation of neuron projection arborization	biological process	GO:0150011	15	1	18204	50	GRIP1
4.043e-02	-3.21	peripheral nervous system neuron development	biological process	GO:0048935	15	1	18204	50	NTRK2
4.043e-02	-3.21	protein homotrimerization	biological process	GO:0070207	15	1	18204	50	SLC1A2
4.043e-02	-3.21	neurotransmitter receptor transport to plasma membrane	biological process	GO:0098877	15	1	18204	50	GRIP1
4.043e-02	-3.21	peripheral nervous system neuron differentiation	biological process	GO:0048934	15	1	18204	50	NTRK2
4.043e-02	-3.21	synapse maturation	biological process	GO:0060074	15	1	18204	50	NFIA
4.043e-02	-3.21	detection of mechanical stimulus involved in sensory perception of sound	biological process	GO:0050910	15	1	18204	50	COL11A1
4.043e-02	-3.21	exit from mitosis	biological process	GO:0010458	15	1	18204	50	NFIA
4.043e-02	-3.21	endosome to plasma membrane protein transport	biological process	GO:0099638	15	1	18204	50	GRIP1
4.043e-02	-3.21	gamma-aminobutyric acid transport	biological process	GO:0015812	15	1	18204	50	SLC6A11
4.043e-02	-3.21	neuroblast division	biological process	GO:0055057	15	1	18204	50	SOX5
4.043e-02	-3.21	establishment of protein localization to postsynaptic membrane	biological process	GO:1903540	15	1	18204	50	GRIP1
4.043e-02	-3.21	cerebellar Purkinje cell layer formation	biological process	GO:0021694	15	1	18204	50	RORA
4.069e-02	-3.20	Formin, FH2 domain	gene3d domains	1.20.58.2220	15	1	14470	40	FHOD3
4.074e-02	-3.20	EPB41L4A (erythrocyte membrane protein band 4.1 like 4A)	protein interactions	64097	127	2	19454	49	FARP1,USP6NL
4.074e-02	-3.20	KRTAP12-2 (keratin associated protein 12-2)	protein interactions	353323	127	2	19454	49	ADAM12,SLC13A5
4.086e-02	-3.20	G protein-coupled receptor signaling pathway	biological process	GO:0007186	1178	7	18204	50	APOA1,SORCS2,DGKB,PREX2,GRK5,ADGRB3,PREX1
4.101e-02	-3.19	Ig-like_dom_sf	interpro domains	IPR036179	483	4	18521	50	FGFRL1,NRCAM,LRIG1,NTRK2
4.121e-02	-3.19	basal_(triple-negative)_carcinoma	COSMIC cancer mutations	basal_(triple-negative)_carcinoma	2981	14	16828	49	PRDM16,NPAS3,SLC39A12,FHOD3,LPIN2,ELOVL2,ADAM12,EGF,TNS3,NRCAM,NTRK2,MSI2,COL11A1,SLC4A4
4.121e-02	-3.19	breast-carcinoma-basal_(triple-negative)_carcinoma	COSMIC cancer mutations	breast-carcinoma-basal_(triple-negative)_carcinoma	2981	14	16828	49	NPAS3,PRDM16,ADAM12,LPIN2,ELOVL2,FHOD3,SLC39A12,TNS3,NRCAM,EGF,SLC4A4,COL11A1,MSI2,NTRK2
4.127e-02	-3.19	human chr3q13.31	chromosome location	human chr3q13.31	22	1	26134	50	ZBTB20
4.132e-02	-3.19	TEAD2 (TEA domain transcription factor 2)	protein interactions	8463	128	2	19454	49	ZBTB20,TRPS1
4.132e-02	-3.19	MYB (MYB proto-oncogene, transcription factor)	protein interactions	4602	128	2	19454	49	TRPS1,NFIA
4.134e-02	-3.19	FH2	pfam domains	PF02181	15	1	17795	50	FHOD3
4.134e-02	-3.19	FKBP_C	pfam domains	PF00254	15	1	17795	50	FKBP5
4.134e-02	-3.19	DAGK_cat	pfam domains	PF00781	15	1	17795	50	DGKB
4.151e-02	-3.18	DISINTEGRIN	prints domains	PR00289	13	1	5227	17	ADAM12
4.158e-02	-3.18	SH3 domain binding	molecular function	GO:0017124	122	2	18094	48	QKI,ADAM12
4.163e-02	-3.18	water channel activity	molecular function	GO:0015250	16	1	18094	48	AQP4
4.163e-02	-3.18	oxysterol binding	molecular function	GO:0008142	16	1	18094	48	RORA
4.163e-02	-3.18	sodium:chloride symporter activity	molecular function	GO:0015378	16	1	18094	48	SLC6A11
4.170e-02	-3.18	synapse assembly	biological process	GO:0007416	118	2	18204	50	FARP1,NRCAM
4.190e-02	-3.17	Lima1 (LIM domain and actin binding 1)	protein interactions	65970	129	2	19454	49	ITPR2,ZBTB20
4.193e-02	-3.17	cell surface receptor signaling pathway	biological process	GO:0007166	1992	10	18204	50	GRK5,CTNND2,ADGRB3,FGFRL1,NFIA,PTN,APOA1,EGF,NTRK2,FARP1
4.198e-02	-3.17	Shcbp1 (Shc SH2-domain binding protein 1)	protein interactions	20419	17	1	19454	49	GPC5
4.198e-02	-3.17	PLCE1 (phospholipase C epsilon 1)	protein interactions	51196	17	1	19454	49	FKBP5
4.198e-02	-3.17	MSANTD2 (Myb/SANT DNA binding domain containing 2)	protein interactions	79684	17	1	19454	49	SOX5
4.198e-02	-3.17	TAC3 (tachykinin precursor 3)	protein interactions	6866	17	1	19454	49	PTN
4.198e-02	-3.17	NFASC (neurofascin)	protein interactions	23114	17	1	19454	49	NRCAM
4.198e-02	-3.17	TAGAP (T cell activation RhoGTPase activating protein)	protein interactions	117289	17	1	19454	49	SNTB1
4.198e-02	-3.17	Nufip2 (nuclear FMR1 interacting protein 2)	protein interactions	68564	17	1	19454	49	CTBP1
4.198e-02	-3.17	HPR (haptoglobin-related protein)	protein interactions	3250	17	1	19454	49	APOA1
4.198e-02	-3.17	UBA7 (ubiquitin like modifier activating enzyme 7)	protein interactions	7318	17	1	19454	49	GRIP1
4.198e-02	-3.17	CNTN2 (contactin 2)	protein interactions	6900	17	1	19454	49	NRCAM
4.198e-02	-3.17	Pef1 (penta-EF hand domain containing 1)	protein interactions	67898	17	1	19454	49	QKI
4.198e-02	-3.17	STK32A (serine/threonine kinase 32A)	protein interactions	202374	17	1	19454	49	FKBP5
4.235e-02	-3.16	Ez/rad/moesin-like	interpro domains	IPR000798	16	1	18521	50	FARP1
4.235e-02	-3.16	Disintegrin_CS	interpro domains	IPR018358	16	1	18521	50	ADAM12
4.240e-02	-3.16	ZnF_GATA	smart domains	SM00401	12	1	9717	35	TRPS1
4.240e-02	-3.16	DWA	smart domains	SM00523	12	1	9717	35	NFIA
4.252e-02	-3.16	Composition of Lipid Particles	WikiPathways	WP3601	10	1	5310	23	APOA1
4.267e-02	-3.15	neuron projection terminus	cellular component	GO:0044306	128	2	19108	49	SLC1A2,NTRK2
4.273e-02	-3.15	presynaptic active zone cytoplasmic component	cellular component	GO:0098831	17	1	19108	49	CTBP1
4.282e-02	-3.15	hypothalamus	COSMIC cancer mutations	hypothalamus	15	1	16828	49	QKI
4.290e-02	-3.15	ERBB2 Regulates Cell Motility	REACTOME pathways	R-HSA-6785631	15	1	10285	30	EGF
4.290e-02	-3.15	alpha-linolenic (omega3) and linoleic (omega6) acid metabolism	REACTOME pathways	R-HSA-2046104	15	1	10285	30	ELOVL2
4.290e-02	-3.15	alpha-linolenic acid (ALA) metabolism	REACTOME pathways	R-HSA-2046106	15	1	10285	30	ELOVL2
4.290e-02	-3.15	Depolymerisation of the Nuclear Lamina	REACTOME pathways	R-HSA-4419969	15	1	10285	30	LPIN2
4.307e-02	-3.14	estrous cycle	biological process	GO:0044849	16	1	18204	50	PTN
4.307e-02	-3.14	regulation of hepatocyte proliferation	biological process	GO:2000345	16	1	18204	50	PTN
4.307e-02	-3.14	asymmetric cell division	biological process	GO:0008356	16	1	18204	50	SOX5
4.307e-02	-3.14	non-proteinogenic amino acid biosynthetic process	biological process	GO:0170043	16	1	18204	50	SLC1A3
4.307e-02	-3.14	response to lithium ion	biological process	GO:0010226	16	1	18204	50	SLC13A5
4.307e-02	-3.14	positive regulation of dendrite development	biological process	GO:1900006	16	1	18204	50	PTN
4.307e-02	-3.14	nonribosomal peptide biosynthetic process	biological process	GO:0019184	16	1	18204	50	SLC1A2
4.308e-02	-3.14	ZNF609 (zinc finger protein 609)	protein interactions	23060	131	2	19454	49	SOX5,NFIA
4.308e-02	-3.14	NCOA2 (nuclear receptor coactivator 2)	protein interactions	10499	131	2	19454	49	NFIA,RORA
4.312e-02	-3.14	C11orf52 (chromosome 11 open reading frame 52)	protein interactions	91894	310	3	19454	49	USP6NL,FARP1,GRIP1
4.352e-02	-3.13	skin-chest-malignant_melanoma	COSMIC cancer mutations	skin-chest-malignant_melanoma	114	2	16828	49	SLC6A11,PREX2
4.362e-02	-3.13	bone-extraskeletal-Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour	COSMIC cancer mutations	bone-extraskeletal-Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour	891	6	16828	49	LRIG1,SLC6A11,PTPRZ1,ITPR2,NPAS3,NCKAP5
4.377e-02	-3.13	developmental maturation	biological process	GO:0021700	286	3	18204	50	NFIA,ADGRB3,NRCAM
4.392e-02	-3.13	large_intestine-caecum-carcinoma-adenocarcinoma	COSMIC cancer mutations	large_intestine-caecum-carcinoma-adenocarcinoma	14236	46	16828	49	SLC39A12,SOX5,NPAS3,SLC13A5,SLC4A4,NTRK2,PREX1,FGFRL1,NFIA,PRDM16,GRK5,ITPK1,COL11A1,ITPR2,TNS3,SNTB1,EGF,LPIN2,PTPRZ1,TRPS1,RFX4,FKBP5,PREX2,ZBTB20,NRCAM,NCKAP5,DGKB,QKI,SLC6A11,LRIG1,ELOVL2,ADAM12,CTBP1,FHOD3,AQP4,GRIP1,RORA,USP6NL,SORCS2,GPC5,SLC1A3,CTNND2,NHSL1,FARP1,SLC1A2,APOA1
4.400e-02	-3.12	basal part of cell	cellular component	GO:0045178	307	3	19108	49	SLC1A3,AQP4,SLC4A4
4.415e-02	-3.12	ossification	biological process	GO:0001503	287	3	18204	50	PTN,GPM6B,COL11A1
4.417e-02	-3.12	transmembrane receptor protein tyrosine phosphatase activity	molecular function	GO:0005001	17	1	18094	48	PTPRZ1
4.417e-02	-3.12	transmembrane receptor protein phosphatase activity	molecular function	GO:0019198	17	1	18094	48	PTPRZ1
4.427e-02	-3.12	DUT (deoxyuridine triphosphatase)	protein interactions	1854	133	2	19454	49	CTBP1,FKBP5
4.440e-02	-3.11	TLCD1 (TLC domain containing 1)	protein interactions	116238	18	1	19454	49	SLC39A12
4.440e-02	-3.11	RAI2 (retinoic acid induced 2)	protein interactions	10742	18	1	19454	49	CTBP1
4.440e-02	-3.11	CYP2E1 (cytochrome P450 family 2 subfamily E member 1)	protein interactions	1571	18	1	19454	49	PTN
4.440e-02	-3.11	DCAF17 (DDB1 and CUL4 associated factor 17)	protein interactions	80067	18	1	19454	49	PREX1
4.440e-02	-3.11	TOR2A (torsin family 2 member A)	protein interactions	27433	18	1	19454	49	CTBP1
4.464e-02	-3.11	MINTRINSICP	prints domains	PR00783	14	1	5227	17	AQP4
4.493e-02	-3.10	ATP-NAD_kinase_N	interpro domains	IPR017438	17	1	18521	50	DGKB
4.493e-02	-3.10	CA_dom	interpro domains	IPR001148	17	1	18521	50	PTPRZ1
4.493e-02	-3.10	NAD/diacylglycerol_kinase_sf	interpro domains	IPR016064	17	1	18521	50	DGKB
4.493e-02	-3.10	CA_dom_sf	interpro domains	IPR036398	17	1	18521	50	PTPRZ1
4.494e-02	-3.10	LDLRB	prosite domains	PS51120	13	1	12186	43	EGF
4.494e-02	-3.10	ATP_GRASP	prosite domains	PS50975	13	1	12186	43	ITPK1
4.507e-02	-3.10	ductal_carcinoma	COSMIC cancer mutations	ductal_carcinoma	15798	49	16828	49	GRIP1,RORA,AQP4,GPM6B,FHOD3,CTBP1,LRIG1,ELOVL2,SLC6A11,ADAM12,APOA1,SLC1A3,SLC1A2,NHSL1,FARP1,CTNND2,GPC5,USP6NL,SORCS2,FKBP5,TRPS1,RFX4,PTPRZ1,LPIN2,NCKAP5,DGKB,QKI,NRCAM,PTN,ZBTB20,PREX2,MSI2,PRDM16,NFIA,PREX1,FGFRL1,SNTB1,EGF,TNS3,ITPR2,GRK5,COL11A1,ITPK1,SLC13A5,NPAS3,SOX5,SLC39A12,NTRK2,SLC4A4
4.512e-02	-3.10	caecum	COSMIC cancer mutations	caecum	14248	46	16828	49	SORCS2,USP6NL,GPC5,NHSL1,SLC1A2,FARP1,CTNND2,SLC1A3,APOA1,ADAM12,LRIG1,ELOVL2,SLC6A11,FHOD3,CTBP1,AQP4,RORA,GRIP1,PREX2,ZBTB20,NRCAM,QKI,NCKAP5,DGKB,LPIN2,PTPRZ1,RFX4,TRPS1,FKBP5,COL11A1,ITPK1,GRK5,ITPR2,TNS3,EGF,SNTB1,FGFRL1,PREX1,NFIA,PRDM16,SLC4A4,NTRK2,SLC39A12,SOX5,SLC13A5,NPAS3
4.519e-02	-3.10	dystrophin-associated glycoprotein complex	cellular component	GO:0016010	18	1	19108	49	SNTB1
4.525e-02	-3.10	kinase activity	molecular function	GO:0016301	739	5	18094	48	GRK5,DGKB,ITPK1,FGFRL1,NTRK2
4.547e-02	-3.09	JAK3 (Janus kinase 3)	protein interactions	3718	135	2	19454	49	APOA1,FKBP5
4.547e-02	-3.09	SOX15 (SRY-box transcription factor 15)	protein interactions	6665	135	2	19454	49	NFIA,TRPS1
4.547e-02	-3.09	NTRK2 (neurotrophic receptor tyrosine kinase 2)	protein interactions	4915	135	2	19454	49	NTRK2,USP6NL
4.547e-02	-3.09	Myo1c (myosin IC)	protein interactions	17913	135	2	19454	49	ITPR2,TRPS1
4.556e-02	-3.09	LGALS1 (galectin 1)	protein interactions	3956	317	3	19454	49	NRCAM,PTPRZ1,FKBP5
4.558e-02	-3.09	cellular process	biological process	GO:0009987	14996	46	18204	50	COL11A1,NRCAM,NTRK2,NFIA,ITPK1,ADAM12,PREX1,GRIP1,USP6NL,GRK5,LPIN2,FARP1,SLC4A4,APOA1,EGF,SOX5,FGFRL1,PTPRZ1,RORA,AQP4,PRDM16,CTBP1,FKBP5,NHSL1,GPC5,SORCS2,SLC13A5,SLC1A3,SLC39A12,PTN,ELOVL2,GPM6B,DGKB,RFX4,MSI2,TNS3,NCKAP5,SLC6A11,FHOD3,ITPR2,ZBTB20,PREX2,QKI,ADGRB3,SLC1A2,CTNND2
4.560e-02	-3.09	positive regulation of cell-substrate adhesion	biological process	GO:0010811	124	2	18204	50	PREX1,APOA1
4.560e-02	-3.09	regulation of ossification	biological process	GO:0030278	124	2	18204	50	PTN,GPM6B
4.560e-02	-3.09	action potential	biological process	GO:0001508	124	2	18204	50	NTRK2,NRCAM
4.560e-02	-3.09	positive regulation of lipid metabolic process	biological process	GO:0045834	124	2	18204	50	APOA1,ZBTB20
4.570e-02	-3.09	Constitutive Signaling by EGFRvIII	REACTOME pathways	R-HSA-5637810	16	1	10285	30	EGF
4.570e-02	-3.09	PI3K events in ERBB2 signaling	REACTOME pathways	R-HSA-1963642	16	1	10285	30	EGF
4.570e-02	-3.09	GRB2 events in ERBB2 signaling	REACTOME pathways	R-HSA-1963640	16	1	10285	30	EGF
4.570e-02	-3.09	Signaling by EGFRvIII in Cancer	REACTOME pathways	R-HSA-5637812	16	1	10285	30	EGF
4.570e-02	-3.09	regulation of Golgi organization	biological process	GO:1903358	17	1	18204	50	USP6NL
4.570e-02	-3.09	reverse cholesterol transport	biological process	GO:0043691	17	1	18204	50	APOA1
4.570e-02	-3.09	regulation of receptor clustering	biological process	GO:1903909	17	1	18204	50	FARP1
4.570e-02	-3.09	protein trimerization	biological process	GO:0070206	17	1	18204	50	SLC1A2
4.570e-02	-3.09	phospholipid homeostasis	biological process	GO:0055091	17	1	18204	50	APOA1
4.570e-02	-3.09	T-helper 17 type immune response	biological process	GO:0072538	17	1	18204	50	RORA
4.570e-02	-3.09	retinal rod cell differentiation	biological process	GO:0060221	17	1	18204	50	NTRK2
4.570e-02	-3.09	ureter development	biological process	GO:0072189	17	1	18204	50	NFIA
4.570e-02	-3.09	white fat cell differentiation	biological process	GO:0050872	17	1	18204	50	CTBP1
4.570e-02	-3.09	postsynaptic actin cytoskeleton organization	biological process	GO:0098974	17	1	18204	50	FARP1
4.570e-02	-3.09	high-density lipoprotein particle remodeling	biological process	GO:0034375	17	1	18204	50	APOA1
4.570e-02	-3.09	cGMP metabolic process	biological process	GO:0046068	17	1	18204	50	RORA
4.585e-02	-3.08	FA	smart domains	SM01195	13	1	9717	35	FARP1
4.599e-02	-3.08	-	gene3d domains	2.60.120.1000	17	1	14470	40	COL11A1
4.599e-02	-3.08	Alpha carbonic anhydrase	gene3d domains	3.10.200.10	17	1	14470	40	PTPRZ1
4.606e-02	-3.08	extraskeletal	COSMIC cancer mutations	extraskeletal	903	6	16828	49	SLC6A11,LRIG1,NPAS3,NCKAP5,ITPR2,PTPRZ1
4.608e-02	-3.08	SNX9 (sorting nexin 9)	protein interactions	51429	136	2	19454	49	SLC1A3,CTBP1
4.631e-02	-3.07	modulation of chemical synaptic transmission	biological process	GO:0050804	494	4	18204	50	SLC1A3,SORCS2,NTRK2,PTN
4.660e-02	-3.07	regulation of trans-synaptic signaling	biological process	GO:0099177	495	4	18204	50	PTN,SORCS2,NTRK2,SLC1A3
4.662e-02	-3.07	heat shock protein binding	molecular function	GO:0031072	130	2	18094	48	APOA1,FKBP5
4.671e-02	-3.06	transmembrane receptor protein tyrosine kinase activator activity	molecular function	GO:0030297	18	1	18094	48	EGF
4.671e-02	-3.06	intracellularly gated calcium channel activity	molecular function	GO:0015278	18	1	18094	48	ITPR2
4.671e-02	-3.06	monoatomic anion:sodium symporter activity	molecular function	GO:0015373	18	1	18094	48	SLC6A11
4.673e-02	-3.06	Carb_anhydrase	pfam domains	PF00194	17	1	17795	50	PTPRZ1
4.673e-02	-3.06	PRDM2_PR	pfam domains	PF21549	17	1	17795	50	PRDM16
4.677e-02	-3.06	human chr7q31.1	chromosome location	human chr7q31.1	25	1	26134	50	NRCAM
4.681e-02	-3.06	INKA1 (inka box actin regulator 1)	protein interactions	389119	19	1	19454	49	ZBTB20
4.681e-02	-3.06	TNR (tenascin R)	protein interactions	7143	19	1	19454	49	PTPRZ1
4.681e-02	-3.06	HMGCLL1 (3-hydroxy-3-methylglutaryl-CoA lyase like 1)	protein interactions	54511	19	1	19454	49	APOA1
4.681e-02	-3.06	PDIK1L (PDLIM1 interacting kinase 1 like)	protein interactions	149420	19	1	19454	49	FKBP5
4.681e-02	-3.06	APOBEC3G (apolipoprotein B mRNA editing enzyme catalytic subunit 3G)	protein interactions	60489	19	1	19454	49	PTN
4.681e-02	-3.06	SPZ1 (spermatogenic leucine zipper 1)	protein interactions	84654	19	1	19454	49	SNTB1
4.681e-02	-3.06	CEP68 (centrosomal protein 68)	protein interactions	23177	19	1	19454	49	CTBP1
4.681e-02	-3.06	FBLN7 (fibulin 7)	protein interactions	129804	19	1	19454	49	APOA1
4.681e-02	-3.06	HSPBAP1 (HSPB1 associated protein 1)	protein interactions	79663	19	1	19454	49	PTN
4.681e-02	-3.06	RCVRN (recoverin)	protein interactions	5957	19	1	19454	49	GRK5
4.693e-02	-3.06	ear morphogenesis	biological process	GO:0042471	126	2	18204	50	COL11A1,LRIG1
4.722e-02	-3.05	central_nervous_system-brain-glioma-astrocytoma_Grade_IV	COSMIC cancer mutations	central_nervous_system-brain-glioma-astrocytoma_Grade_IV	15813	49	16828	49	NFIA,PRDM16,PREX1,FGFRL1,TNS3,SNTB1,EGF,GRK5,ITPK1,COL11A1,ITPR2,SOX5,NPAS3,SLC13A5,SLC39A12,SLC4A4,NTRK2,GPM6B,AQP4,GRIP1,RORA,SLC6A11,LRIG1,ELOVL2,ADAM12,CTBP1,FHOD3,SLC1A3,CTNND2,SLC1A2,NHSL1,FARP1,APOA1,USP6NL,SORCS2,GPC5,TRPS1,RFX4,FKBP5,LPIN2,PTPRZ1,NRCAM,PTN,NCKAP5,DGKB,QKI,MSI2,PREX2,ZBTB20
4.728e-02	-3.05	localization	biological process	GO:0051179	4474	18	18204	50	SLC13A5,SLC39A12,SLC1A3,SORCS2,NTRK2,NRCAM,CTBP1,GRIP1,USP6NL,PTN,GPM6B,APOA1,ITPR2,SLC4A4,SLC6A11,SLC1A2,AQP4,QKI
4.730e-02	-3.05	GRK6 (G protein-coupled receptor kinase 6)	protein interactions	2870	138	2	19454	49	FKBP5,GRK5
4.752e-02	-3.05	PPIase_dom_sf	interpro domains	IPR046357	18	1	18521	50	FKBP5
4.752e-02	-3.05	Leu-rich_rpt_4	interpro domains	IPR025875	18	1	18521	50	LRIG1
4.760e-02	-3.05	response to amino acid	biological process	GO:0043200	127	2	18204	50	NTRK2,SLC1A2
4.760e-02	-3.05	cardiac ventricle development	biological process	GO:0003231	127	2	18204	50	COL11A1,FGFRL1
4.760e-02	-3.05	cardiac chamber morphogenesis	biological process	GO:0003206	127	2	18204	50	COL11A1,FGFRL1
4.772e-02	-3.04	haematopoietic_and_lymphoid_tissue-abdomen-lymphoid_neoplasm-diffuse_large_B_cell_lymphoma	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue-abdomen-lymphoid_neoplasm-diffuse_large_B_cell_lymphoma	120	2	16828	49	CTNND2,PRDM16
4.793e-02	-3.04	skin-back-malignant_melanoma	COSMIC cancer mutations	skin-back-malignant_melanoma	280	3	16828	49	SLC6A11,PREX2,ADAM12
4.821e-02	-3.03	Signalling by NGF	REACTOME pathways	R-HSA-166520	477	4	10285	30	NTRK2,EGF,ITPR2,PREX1
4.822e-02	-3.03	regulation of hydrolase activity	biological process	GO:0051336	726	5	18204	50	PREX2,NTRK2,PREX1,APOA1,USP6NL
4.822e-02	-3.03	cell population proliferation	biological process	GO:0008283	726	5	18204	50	APOA1,EGF,RORA,NFIA,SOX5
4.827e-02	-3.03	glial cell development	biological process	GO:0021782	128	2	18204	50	NTRK2,GPM6B
4.832e-02	-3.03	positive regulation of circadian rhythm	biological process	GO:0042753	18	1	18204	50	RORA
4.832e-02	-3.03	negative regulation of anoikis	biological process	GO:2000811	18	1	18204	50	NTRK2
4.832e-02	-3.03	neuron projection arborization	biological process	GO:0140058	18	1	18204	50	PTN
4.832e-02	-3.03	cardiac myofibril assembly	biological process	GO:0055003	18	1	18204	50	FHOD3
4.832e-02	-3.03	dendritic spine morphogenesis	biological process	GO:0060997	18	1	18204	50	CTNND2
4.839e-02	-3.03	optic_nerve	COSMIC cancer mutations	optic_nerve	17	1	16828	49	QKI
4.839e-02	-3.03	central_nervous_system-optic_nerve-glioma-astrocytoma_Grade_I	COSMIC cancer mutations	central_nervous_system-optic_nerve-glioma-astrocytoma_Grade_I	17	1	16828	49	QKI
4.848e-02	-3.03	Trafficking of GluR2-containing AMPA receptors	REACTOME pathways	R-HSA-416993	17	1	10285	30	GRIP1
4.848e-02	-3.03	Elevation of cytosolic Ca2+ levels	REACTOME pathways	R-HSA-139853	17	1	10285	30	ITPR2
4.853e-02	-3.03	SATB2 (SATB homeobox 2)	protein interactions	23314	140	2	19454	49	NFIA,SOX5
4.863e-02	-3.02	-	gene3d domains	3.10.50.40	18	1	14470	40	FKBP5
4.880e-02	-3.02	DTX2 (deltex E3 ubiquitin ligase 2)	protein interactions	113878	326	3	19454	49	NFIA,CTBP1,USP6NL
4.893e-02	-3.02	phosphorylation	biological process	GO:0016310	729	5	18204	50	NTRK2,GRK5,ITPK1,CTBP1,DGKB
4.911e-02	-3.01	sequence-specific double-stranded DNA binding	molecular function	GO:1990837	1547	8	18094	48	RORA,NPAS3,TRPS1,RFX4,ZBTB20,NFIA,PRDM16,SOX5
4.916e-02	-3.01	LLGL1 (LLGL scribble cell polarity complex component 1)	protein interactions	3996	141	2	19454	49	FKBP5,NTRK2
4.916e-02	-3.01	MAEA (macrophage erythroblast attacher, E3 ubiquitin ligase)	protein interactions	10296	141	2	19454	49	NCKAP5,GRK5
4.916e-02	-3.01	AP3M1 (adaptor related protein complex 3 subunit mu 1)	protein interactions	26985	141	2	19454	49	AQP4,GRK5
4.921e-02	-3.01	DOK5 (docking protein 5)	protein interactions	55816	20	1	19454	49	NTRK2
4.921e-02	-3.01	PON1 (paraoxonase 1)	protein interactions	5444	20	1	19454	49	APOA1
4.921e-02	-3.01	LBP (lipopolysaccharide binding protein)	protein interactions	3929	20	1	19454	49	APOA1
4.921e-02	-3.01	Trappc8 (trafficking protein particle complex 8)	protein interactions	75964	20	1	19454	49	FARP1
4.921e-02	-3.01	ANXA13 (annexin A13)	protein interactions	312	20	1	19454	49	MSI2
4.921e-02	-3.01	NCAM2 (neural cell adhesion molecule 2)	protein interactions	4685	20	1	19454	49	CTNND2
4.921e-02	-3.01	SERPINA4 (serpin family A member 4)	protein interactions	5267	20	1	19454	49	CTBP1
4.921e-02	-3.01	SNCB (synuclein beta)	protein interactions	6620	20	1	19454	49	GRK5
4.921e-02	-3.01	FNDC1 (fibronectin type III domain containing 1)	protein interactions	84624	20	1	19454	49	APOA1
4.921e-02	-3.01	ADRA1D (adrenoceptor alpha 1D)	protein interactions	146	20	1	19454	49	SNTB1
4.921e-02	-3.01	TOR4A (torsin family 4 member A)	protein interactions	54863	20	1	19454	49	GRK5
4.921e-02	-3.01	Pspc1 (paraspeckle protein 1)	protein interactions	66645	20	1	19454	49	CTBP1
4.921e-02	-3.01	PDZD2 (PDZ domain containing 2)	protein interactions	23037	20	1	19454	49	CTNND2
4.924e-02	-3.01	water transmembrane transporter activity	molecular function	GO:0005372	19	1	18094	48	AQP4
4.924e-02	-3.01	secondary active monocarboxylate transmembrane transporter activity	molecular function	GO:0015355	19	1	18094	48	SLC6A11
4.924e-02	-3.01	lipid phosphatase activity	molecular function	GO:0042577	19	1	18094	48	LPIN2
4.924e-02	-3.01	ankyrin binding	molecular function	GO:0030506	19	1	18094	48	NRCAM
4.930e-02	-3.01	LY	smart domains	SM00135	14	1	9717	35	EGF
4.930e-02	-3.01	DAGKc	smart domains	SM00046	14	1	9717	35	DGKB
4.930e-02	-3.01	EGFR-dependent Endothelin signaling events	Pathway Interaction DB	et_egfrpathway	8	1	2226	14	EGF
4.933e-02	-3.01	haematopoietic_and_lymphoid_tissue-lymph_node-lymphoid_neoplasm-mantle_cell_lymphoma	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue-lymph_node-lymphoid_neoplasm-mantle_cell_lymphoma	476	4	16828	49	SORCS2,CTNND2,COL11A1,GPC5
4.933e-02	-3.01	parathyroid	COSMIC cancer mutations	parathyroid	476	4	16828	49	TRPS1,TNS3,GPC5,GRIP1
4.941e-02	-3.01	LRR_4	pfam domains	PF12799	18	1	17795	50	LRIG1
4.941e-02	-3.01	ADAM_CR	pfam domains	PF08516	18	1	17795	50	ADAM12
4.951e-02	-3.01	cellular response to organonitrogen compound	biological process	GO:0071417	505	4	18204	50	ITPR2,SLC1A3,SLC1A2,LPIN2
4.956e-02	-3.00	RBBP4 (RB binding protein 4, chromatin remodeling factor)	protein interactions	5928	551	4	19454	49	CTBP1,ZBTB20,TRPS1,PRDM16
4.968e-02	-3.00	Notch signaling pathway	Pathway Interaction DB	notch_pathway	58	2	2226	14	CTBP1,ADAM12
4.978e-02	-3.00	GIT1 (GIT ArfGAP 1)	protein interactions	28964	142	2	19454	49	PTPRZ1,GRK5
4.978e-02	-3.00	SDC2 (syndecan 2)	protein interactions	6383	142	2	19454	49	FARP1,FGFRL1
4.978e-02	-3.00	GOLM1 (golgi membrane protein 1)	protein interactions	51280	142	2	19454	49	SLC13A5,SLC39A12
4.991e-02	-3.00	NCOR1 (nuclear receptor corepressor 1)	protein interactions	9611	329	3	19454	49	SOX5,CTBP1,NFIA