Gene Ontology Enrichment Results

Homer de novo Motif Enrichment Results
Known Motif Enrichment Results

Text file version of complete results (i.e. open with Excel)

biological process: Functional groupings of proteins (Gene Ontology)

molecular function: Mechanistic actions of proteins (Gene Ontology)

cellular component: Protein localization (Gene Ontology)

chromosome location: Genes with similar chromosome localization (NCBI Gene)

KEGG pathways: Groups of proteins in the same pathways (KEGG)

protein interactions: "Proteins interacting with a common protein (BIND, EcoCyc, HPRD)" (NCBI Gene)

interpro domains: Proteins with similar domains and features (Interpro)

pfam domains: Proteins with similar domains and features (Pfam)

smart domains: Proteins with similar domains and features (SMART)

gene3d domains: Proteins with similar domains and features (Gene3D)

prosite domains: Proteins with similar domains and features (Prosite)

prints domains: Proteins with similar domains and features (PRINTS)

MSigDB lists: "Genes sets for pathways, factor/miRNA target predictions, expression patterns, etc." (MSigDB)

BIOCYC pathways: Groups of proteins in the same pathways (BIOCYC)

COSMIC cancer mutations: Genes mutated in similar cancers (COSMIC)

GWAS genes: Genes mutated in similar diseases (GWAS Catalog)

Lipid Maps pathways: Groups of proteins in the same lipid pathways (Lipid Maps/Biosystems)

Pathway Interaction DB: Groups of proteins in the same pathways (Pathway Interaction Database)

REACTOME pathways: Groups of proteins in the same pathways (REACTOME)

SMPDB pathways: Groups of proteins in the same pathways (SMPDB)

WikiPathways: Groups of proteins in the same pathways (Wikipathways)

Enriched Categories

P-value	ln(P)	Term	GO Tree	GO ID	# of Genes in Term	# of Target Genes in Term	# of Total Genes	# of Target Genes	Common Genes
2.518e-09	-19.80	central_nervous_system-brain-primitive_neuroectodermal_tumour-medulloblastoma	COSMIC cancer mutations	central_nervous_system-brain-primitive_neuroectodermal_tumour-medulloblastoma	7205	40	16828	47	FHOD3,NFIA,PREX2,SLC1A2,ELOVL2,FGFR3,LAMA4,PREX1,PRDM16,FARP1,ZBTB20,FKBP5,RORA,PTN,UNC93A,NHSL1,NCKAP5,QKI,BCAR3,LRIG1,DGKB,TRPS1,GPM6B,SNTB1,EGF,GRK5,SLC4A4,SLC39A12,SOX5,USP6NL,SLC1A3,SLC6A11,GPC5,TNS3,PTPRZ1,NPAS3,LPIN2,RFX4,ASPA,SORCS2
7.912e-09	-18.65	acute_myeloid_leukaemia_therapy_related	COSMIC cancer mutations	acute_myeloid_leukaemia_therapy_related	1523	19	16828	47	GRK5,PREX1,PRDM16,LAMA4,SOX5,DGKB,FHOD3,PREX2,QKI,NCKAP5,BCAR3,AMOT,SORCS2,FARP1,SLC1A3,RORA,SLC6A11,TNS3,GPC5
7.912e-09	-18.65	haematopoietic_and_lymphoid_tissue-haematopoietic_neoplasm-acute_myeloid_leukaemia_therapy_related	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue-haematopoietic_neoplasm-acute_myeloid_leukaemia_therapy_related	1523	19	16828	47	DGKB,PREX2,FHOD3,GRK5,LAMA4,SOX5,PREX1,PRDM16,RORA,SLC1A3,FARP1,GPC5,TNS3,SLC6A11,AMOT,BCAR3,NCKAP5,QKI,SORCS2
1.026e-08	-18.39	system development	biological process	GO:0048731	3533	28	18204	50	AMOT,TRPS1,ADGRB3,QKI,NFIA,SOX5,PRKN,RORA,SLC39A12,LRIG1,FGFR3,PLPP3,FGFRL1,PTN,PREX2,RFX4,EGF,FARP1,SLC1A2,BCAR3,APOA1,GJA1,SLC1A3,ASPA,MSI2,FHOD3,GPM6B,PTPRZ1
3.348e-08	-17.21	cell junction	cellular component	GO:0030054	2224	21	19108	49	QKI,DGKB,PTN,FGFR3,PLPP3,ADGRB3,SNTB1,PRKN,SORCS2,SLC1A3,PTPRZ1,NFIA,FGFRL1,AMOT,FARP1,SLC1A2,SLC6A11,CTBP1,BCAR3,GJA1,TNS3
8.769e-08	-16.25	nervous system development	biological process	GO:0007399	2185	21	18204	50	PLPP3,LRIG1,GPM6B,PTPRZ1,PRKN,SOX5,GJA1,RORA,SLC1A3,ASPA,SLC39A12,MSI2,QKI,EGF,ADGRB3,FARP1,SLC1A2,NFIA,RFX4,PTN,PREX2
1.128e-07	-16.00	stomach-carcinoma-intestinal_adenocarcinoma	COSMIC cancer mutations	stomach-carcinoma-intestinal_adenocarcinoma	7225	38	16828	47	FARP1,RORA,ZBTB20,PTN,UNC93A,NHSL1,NCKAP5,QKI,BCAR3,AQP4,APOA1,FHOD3,NFIA,PREX2,SLC1A2,FGFR3,LAMA4,PRDM16,PREX1,USP6NL,SLC6A11,TNS3,PTPRZ1,NPAS3,CTBP1,RFX4,AMOT,SORCS2,LRIG1,DGKB,TRPS1,SNTB1,EGF,GRK5,SLC4A4,SLC39A12,FGFRL1,SOX5
1.128e-07	-16.00	intestinal_adenocarcinoma	COSMIC cancer mutations	intestinal_adenocarcinoma	7225	38	16828	47	GRK5,EGF,SNTB1,SOX5,FGFRL1,SLC4A4,SLC39A12,DGKB,LRIG1,TRPS1,RFX4,AMOT,NPAS3,CTBP1,PTPRZ1,SORCS2,USP6NL,TNS3,SLC6A11,SLC1A2,PREX1,PRDM16,LAMA4,FGFR3,APOA1,PREX2,NFIA,FHOD3,BCAR3,QKI,NCKAP5,AQP4,PTN,RORA,ZBTB20,FARP1,NHSL1,UNC93A
1.344e-07	-15.82	multicellular organism development	biological process	GO:0007275	3957	28	18204	50	PREX2,PTN,RFX4,FARP1,EGF,SLC1A2,BCAR3,APOA1,GJA1,MSI2,ASPA,SLC1A3,FHOD3,PTPRZ1,GPM6B,AMOT,TRPS1,ADGRB3,QKI,NFIA,RORA,PRKN,SOX5,SLC39A12,FGFRL1,LRIG1,PLPP3,FGFR3
4.230e-07	-14.68	brainstem	COSMIC cancer mutations	brainstem	3102	24	16828	47	SOX5,SLC39A12,GRK5,EGF,SNTB1,TNS3,GPC5,SLC1A3,USP6NL,NPAS3,PTPRZ1,PREX2,FHOD3,PRDM16,PREX1,FGFR3,ELOVL2,SLC1A2,PTN,ZBTB20,RORA,BCAR3,QKI,NCKAP5
5.047e-07	-14.50	developmental process	biological process	GO:0032502	5716	33	18204	50	NFIA,ADGRB3,QKI,TRPS1,NHSL1,AMOT,GRK5,LRIG1,FGFR3,PLPP3,FGFRL1,SLC39A12,PRKN,SOX5,PREX1,RORA,BCAR3,SLC1A2,EGF,FARP1,PREX2,PTN,RFX4,CTBP1,PRDM16,GPM6B,PTPRZ1,FHOD3,SLC1A3,ASPA,MSI2,APOA1,GJA1
6.193e-07	-14.29	anatomical structure morphogenesis	biological process	GO:0009653	2225	20	18204	50	PREX2,PTN,AMOT,NFIA,BCAR3,QKI,EGF,ADGRB3,FARP1,SLC1A3,SLC39A12,SOX5,RORA,GJA1,PTPRZ1,PLPP3,FGFR3,FHOD3,LRIG1,FGFRL1
9.820e-07	-13.83	positive regulation of oligodendrocyte differentiation	biological process	GO:0048714	28	4	18204	50	PTN,ASPA,PTPRZ1,QKI
1.309e-06	-13.55	neurotransmitter uptake	biological process	GO:0001504	30	4	18204	50	SLC1A2,SLC1A3,SLC6A11,PRKN
1.699e-06	-13.29	neurogenesis	biological process	GO:0022008	1334	15	18204	50	PTPRZ1,GPM6B,PLPP3,SLC39A12,SLC1A3,ASPA,RORA,GJA1,SOX5,NFIA,FARP1,ADGRB3,QKI,PTN,PREX2
3.587e-06	-12.54	multicellular organismal process	biological process	GO:0032501	6177	33	18204	50	QKI,ADGRB3,NFIA,AMOT,DGKB,SNTB1,TRPS1,FGFRL1,PLPP3,FGFR3,LRIG1,RORA,SOX5,PREX1,PRKN,SLC39A12,FARP1,EGF,BCAR3,SLC1A2,SLC4A4,AQP4,RFX4,PTN,PREX2,FHOD3,PTPRZ1,GPM6B,GJA1,APOA1,MSI2,ASPA,SLC1A3
5.208e-06	-12.17	central_nervous_system-brainstem-glioma-astrocytoma_Grade_IV	COSMIC cancer mutations	central_nervous_system-brainstem-glioma-astrocytoma_Grade_IV	2531	20	16828	47	PREX2,FHOD3,GRK5,SNTB1,PREX1,PRDM16,SOX5,SLC39A12,ELOVL2,PTN,SLC1A3,USP6NL,RORA,ZBTB20,TNS3,GPC5,BCAR3,QKI,PTPRZ1,NCKAP5
7.169e-06	-11.85	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-Burkitt_lymphoma	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-Burkitt_lymphoma	2119	18	16828	47	FHOD3,PREX2,LRIG1,DGKB,SOX5,LAMA4,PRDM16,SNTB1,EGF,SLC1A2,GRK5,NHSL1,GPC5,SLC1A3,SORCS2,NCKAP5,NPAS3,RFX4
7.169e-06	-11.85	Burkitt_lymphoma	COSMIC cancer mutations	Burkitt_lymphoma	2119	18	16828	47	SLC1A3,GPC5,NHSL1,NCKAP5,NPAS3,RFX4,SORCS2,LRIG1,DGKB,FHOD3,PREX2,SNTB1,EGF,GRK5,SLC1A2,SOX5,LAMA4,PRDM16
7.547e-06	-11.79	regulation of oligodendrocyte differentiation	biological process	GO:0048713	46	4	18204	50	QKI,ASPA,PTN,PTPRZ1
7.547e-06	-11.79	positive regulation of glial cell differentiation	biological process	GO:0045687	46	4	18204	50	PTN,ASPA,PTPRZ1,QKI
8.161e-06	-11.72	cell differentiation	biological process	GO:0030154	3645	24	18204	50	GJA1,SLC1A3,ASPA,MSI2,FHOD3,GPM6B,PRDM16,PTPRZ1,CTBP1,PREX2,PTN,FARP1,SOX5,PREX1,RORA,SLC39A12,FGFR3,PLPP3,GRK5,NHSL1,AMOT,QKI,ADGRB3,NFIA
8.282e-06	-11.70	cellular developmental process	biological process	GO:0048869	3648	24	18204	50	FARP1,PTN,PREX2,CTBP1,GPM6B,PRDM16,PTPRZ1,FHOD3,SLC1A3,ASPA,MSI2,GJA1,NFIA,QKI,ADGRB3,NHSL1,AMOT,GRK5,PLPP3,FGFR3,SLC39A12,PREX1,SOX5,RORA
1.305e-05	-11.25	myelodysplastic_syndrome	COSMIC cancer mutations	myelodysplastic_syndrome	1174	13	16828	47	SLC6A11,SORCS2,NCKAP5,NPAS3,FHOD3,NFIA,PREX2,DGKB,FGFR3,SOX5,EGF,GRK5,SLC1A2
1.305e-05	-11.25	haematopoietic_and_lymphoid_tissue-haematopoietic_neoplasm-myelodysplastic_syndrome	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue-haematopoietic_neoplasm-myelodysplastic_syndrome	1174	13	16828	47	SORCS2,NPAS3,NCKAP5,SLC6A11,FGFR3,SOX5,EGF,GRK5,SLC1A2,FHOD3,PREX2,NFIA,DGKB
1.311e-05	-11.24	anatomical structure development	biological process	GO:0048856	5207	29	18204	50	BCAR3,SLC1A2,FARP1,EGF,RFX4,PTN,PREX2,PTPRZ1,GPM6B,FHOD3,MSI2,ASPA,SLC1A3,GJA1,APOA1,NFIA,QKI,ADGRB3,TRPS1,AMOT,FGFRL1,PLPP3,FGFR3,LRIG1,SLC39A12,RORA,PRKN,SOX5,PREX1
1.417e-05	-11.16	chondroblastoma	COSMIC cancer mutations	chondroblastoma	534	9	16828	47	EGF,SNTB1,NCKAP5,PREX1,SOX5,LAMA4,FARP1,GPC5,FHOD3
1.423e-05	-11.16	solute:monoatomic cation symporter activity	molecular function	GO:0015294	117	5	18094	48	SLC1A2,SLC39A12,SLC6A11,SLC4A4,SLC1A3
1.707e-05	-10.98	cell periphery	cellular component	GO:0071944	6020	30	19108	49	GPM6B,DGKB,SNTB1,LAMA4,SLC1A3,PTPRZ1,USP6NL,ADGRB3,AMOT,FARP1,SLC1A2,SLC6A11,AQP4,CTBP1,GJA1,APOA1,PLPP3,PTN,FGFR3,SORCS2,PREX1,EGF,SLC39A12,GPC5,FGFRL1,LRIG1,UNC93A,GRK5,SLC4A4,PREX2
1.861e-05	-10.89	bone-humerus-other-chondroblastoma	COSMIC cancer mutations	bone-humerus-other-chondroblastoma	301	7	16828	47	NCKAP5,EGF,LAMA4,SOX5,FARP1,GPC5,FHOD3
2.071e-05	-10.78	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-acute_lymphoblastic_B_cell_leukaemia	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-acute_lymphoblastic_B_cell_leukaemia	3828	24	16828	47	BCAR3,NCKAP5,ZBTB20,RORA,SLC1A2,PRDM16,LAMA4,PREX2,NFIA,FHOD3,LPIN2,AMOT,PTPRZ1,SORCS2,SLC1A3,USP6NL,TNS3,GPC5,SLC6A11,GRK5,EGF,SNTB1,SOX5,SLC4A4
2.071e-05	-10.78	acute_lymphoblastic_B_cell_leukaemia	COSMIC cancer mutations	acute_lymphoblastic_B_cell_leukaemia	3828	24	16828	47	BCAR3,NCKAP5,RORA,ZBTB20,SLC1A2,LAMA4,PRDM16,NFIA,PREX2,FHOD3,LPIN2,AMOT,PTPRZ1,SORCS2,USP6NL,SLC1A3,GPC5,TNS3,SLC6A11,GRK5,SNTB1,EGF,SOX5,SLC4A4
2.151e-05	-10.75	AKT2 (AKT serine/threonine kinase 2)	protein interactions	208	134	5	19454	49	FKBP5,GJA1,APOA1,GRK5,PRKN
2.892e-05	-10.45	glial cell differentiation	biological process	GO:0010001	219	6	18204	50	PTPRZ1,GPM6B,ASPA,NFIA,QKI,PLPP3
2.894e-05	-10.45	neurotransmitter reuptake	biological process	GO:0098810	22	3	18204	50	PRKN,SLC6A11,SLC1A2
2.989e-05	-10.42	amino acid:sodium symporter activity	molecular function	GO:0005283	23	3	18094	48	SLC1A2,SLC6A11,SLC1A3
3.520e-05	-10.25	plasma membrane	cellular component	GO:0005886	5538	28	19108	49	PLPP3,APOA1,FGFR3,PTN,SORCS2,SLC39A12,EGF,PREX1,FGFRL1,GPC5,SLC4A4,PREX2,LRIG1,UNC93A,GRK5,GPM6B,DGKB,PTPRZ1,SLC1A3,SNTB1,ADGRB3,USP6NL,SLC1A2,FARP1,SLC6A11,AMOT,AQP4,GJA1
3.717e-05	-10.20	Ctbp2 (C-terminal binding protein 2)	protein interactions	13017	4	2	19454	49	PRDM16,TRPS1
3.717e-05	-10.20	GOT1L1 (glutamic-oxaloacetic transaminase 1 like 1)	protein interactions	137362	4	2	19454	49	APOA1,GRK5
3.941e-05	-10.14	haematopoietic_and_lymphoid_tissue-haematopoietic_neoplasm	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue-haematopoietic_neoplasm	764	10	16828	47	DGKB,PREX2,GPC5,FHOD3,SLC6A11,SLC1A2,GRK5,NCKAP5,SORCS2,SOX5
4.065e-05	-10.11	SOX6 (SRY-box transcription factor 6)	protein interactions	55553	153	5	19454	49	CTBP1,SOX5,NFIA,PRDM16,TRPS1
4.135e-05	-10.09	soft_tissue	COSMIC cancer mutations	soft_tissue	5828	30	16828	47	SLC1A3,USP6NL,TNS3,GPC5,NPAS3,CTBP1,PTPRZ1,SORCS2,DGKB,TRPS1,GRK5,EGF,SNTB1,FGFRL1,SOX5,SLC39A12,PTN,RORA,FARP1,NHSL1,GJA1,NCKAP5,AQP4,PREX2,NFIA,FHOD3,SLC1A2,PRDM16,FGFR3,ELOVL2
4.209e-05	-10.08	MBNL2 (muscleblind like splicing regulator 2)	protein interactions	10150	27	3	19454	49	PRKN,MSI2,QKI
4.413e-05	-10.03	symporter activity	molecular function	GO:0015293	148	5	18094	48	SLC6A11,SLC1A2,SLC39A12,SLC4A4,SLC1A3
4.580e-05	-9.99	autonomic_ganglia	COSMIC cancer mutations	autonomic_ganglia	4005	24	16828	47	NHSL1,TNS3,USP6NL,AQP4,SORCS2,PTPRZ1,NCKAP5,NPAS3,RFX4,LPIN2,AMOT,GJA1,TRPS1,FHOD3,NFIA,GPM6B,PREX2,FGFR3,SLC4A4,PREX1,PRDM16,SNTB1,EGF,SLC1A2
4.590e-05	-9.99	Astrocytic Glutamate-Glutamine Uptake And Metabolism	REACTOME pathways	R-HSA-210455	4	2	10285	29	SLC1A3,SLC1A2
4.590e-05	-9.99	Neurotransmitter uptake and Metabolism In Glial Cells	REACTOME pathways	R-HSA-112313	4	2	10285	29	SLC1A3,SLC1A2
5.029e-05	-9.90	positive regulation of gliogenesis	biological process	GO:0014015	74	4	18204	50	PTN,ASPA,PTPRZ1,QKI
5.266e-05	-9.85	generation of neurons	biological process	GO:0048699	1158	12	18204	50	SOX5,RORA,GJA1,PREX2,SLC1A3,PTN,SLC39A12,ADGRB3,FARP1,GPM6B,NFIA,PTPRZ1
5.345e-05	-9.84	blood_vessel	COSMIC cancer mutations	blood_vessel	2211	17	16828	47	PTN,SLC1A3,FARP1,TNS3,GPC5,NCKAP5,PTPRZ1,SORCS2,DGKB,PREX2,FHOD3,SLC1A2,SNTB1,PRDM16,SOX5,FGFR3,SLC39A12
5.377e-05	-9.83	GSC (goosecoid homeobox)	protein interactions	145258	82	4	19454	49	SOX5,NFIA,TRPS1,PRDM16
5.554e-05	-9.80	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm	7307	34	16828	47	FKBP5,RORA,PTN,FARP1,NHSL1,UNC93A,BCAR3,NCKAP5,QKI,PREX2,FHOD3,SLC1A2,LAMA4,PRDM16,PREX1,ELOVL2,USP6NL,SLC1A3,GPC5,TNS3,SLC6A11,RFX4,LPIN2,PTPRZ1,CTBP1,SORCS2,ASPA,LRIG1,DGKB,GRK5,SNTB1,EGF,FGFRL1,SOX5
5.946e-05	-9.73	solute:sodium symporter activity	molecular function	GO:0015370	80	4	18094	48	SLC1A3,SLC4A4,SLC6A11,SLC1A2
6.099e-05	-9.70	amino acid:monoatomic cation symporter activity	molecular function	GO:0005416	29	3	18094	48	SLC1A3,SLC1A2,SLC6A11
6.103e-05	-9.70	synapse	cellular component	GO:0045202	1473	13	19108	49	CTBP1,SLC6A11,FARP1,SLC1A2,ADGRB3,SORCS2,PRKN,SNTB1,PTPRZ1,SLC1A3,PTN,QKI,DGKB
6.243e-05	-9.68	haematopoietic_and_lymphoid_tissue-haematopoietic_neoplasm-mast_cell_neoplasm	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue-haematopoietic_neoplasm-mast_cell_neoplasm	248	6	16828	47	NFIA,GPC5,SORCS2,GRK5,DGKB,NPAS3
6.243e-05	-9.68	mast_cell_neoplasm	COSMIC cancer mutations	mast_cell_neoplasm	248	6	16828	47	NFIA,GPC5,DGKB,SORCS2,GRK5,NPAS3
6.432e-05	-9.65	central nervous system development	biological process	GO:0007417	995	11	18204	50	GPM6B,SLC1A2,PTPRZ1,QKI,EGF,PLPP3,RFX4,ASPA,MSI2,PRKN,RORA
6.501e-05	-9.64	regulation of glial cell differentiation	biological process	GO:0045685	79	4	18204	50	QKI,PTPRZ1,ASPA,PTN
6.856e-05	-9.59	glutamate:sodium symporter activity	molecular function	GO:0015501	5	2	18094	48	SLC1A2,SLC1A3
6.856e-05	-9.59	high-affinity L-glutamate transmembrane transporter activity	molecular function	GO:0005314	5	2	18094	48	SLC1A3,SLC1A2
6.856e-05	-9.59	fibroblast growth factor receptor activity	molecular function	GO:0005007	5	2	18094	48	FGFRL1,FGFR3
7.057e-05	-9.56	carcinoid-endocrine_tumour	COSMIC cancer mutations	carcinoid-endocrine_tumour	7752	35	16828	47	LAMA4,PRDM16,PREX1,ELOVL2,FGFR3,SLC1A2,PREX2,FHOD3,BCAR3,NCKAP5,QKI,NHSL1,UNC93A,FKBP5,RORA,PTN,FARP1,FGFRL1,SOX5,SLC4A4,GRK5,SNTB1,EGF,TRPS1,LRIG1,DGKB,ASPA,RFX4,PTPRZ1,CTBP1,GPC5,TNS3,SLC6A11,USP6NL,SLC1A3
7.058e-05	-9.56	RAB35 (RAB35, member RAS oncogene family)	protein interactions	11021	559	8	19454	49	PLPP3,PRKN,SLC1A3,ELOVL2,USP6NL,AMOT,FARP1,GJA1
7.089e-05	-9.55	DYRK1B (dual specificity tyrosine phosphorylation regulated kinase 1B)	protein interactions	9149	88	4	19454	49	PRKN,LPIN2,CTBP1,FKBP5
7.270e-05	-9.53	organic anion transmembrane transporter activity	molecular function	GO:0008514	268	6	18094	48	SLC4A4,SLC1A3,SLC6A11,GJA1,SLC39A12,SLC1A2
7.355e-05	-9.52	D-aspartate import across plasma membrane	biological process	GO:0070779	5	2	18204	50	SLC1A3,SLC1A2
7.355e-05	-9.52	D-aspartate transmembrane transport	biological process	GO:0070777	5	2	18204	50	SLC1A3,SLC1A2
7.560e-05	-9.49	positive regulation of biological process	biological process	GO:0048518	6326	31	18204	50	AMOT,NFIA,ADGRB3,QKI,SLC39A12,SOX5,PREX1,PRKN,RORA,GRK5,FGFR3,PLPP3,NPAS3,PTN,RFX4,CTBP1,SLC4A4,SLC1A2,BCAR3,GPC5,LPIN2,EGF,FARP1,ASPA,SLC1A3,ZBTB20,APOA1,GJA1,PRDM16,GPM6B,PTPRZ1
8.505e-05	-9.37	HGH1 (HGH1 homolog)	protein interactions	51236	34	3	19454	49	PRKN,FKBP5,PTN
8.584e-05	-9.36	prostate-carcinoma	COSMIC cancer mutations	prostate-carcinoma	9000	38	16828	47	DGKB,LRIG1,TRPS1,GRK5,EGF,SNTB1,FGFRL1,SOX5,SLC39A12,SLC4A4,SLC1A3,TNS3,GPC5,RFX4,LPIN2,NPAS3,PTPRZ1,SORCS2,ASPA,MSI2,APOA1,PREX2,NFIA,FHOD3,SLC1A2,PREX1,PRDM16,LAMA4,FGFR3,ELOVL2,ZBTB20,RORA,FARP1,NHSL1,UNC93A,BCAR3,QKI,NCKAP5
1.024e-04	-9.19	gliogenesis	biological process	GO:0042063	275	6	18204	50	PTPRZ1,GPM6B,NFIA,PLPP3,QKI,ASPA
1.080e-04	-9.13	organic acid:sodium symporter activity	molecular function	GO:0005343	35	3	18094	48	SLC1A3,SLC1A2,SLC6A11
1.101e-04	-9.11	L-aspartate import across plasma membrane	biological process	GO:0140009	6	2	18204	50	SLC1A2,SLC1A3
1.101e-04	-9.11	D-amino acid transport	biological process	GO:0042940	6	2	18204	50	SLC1A3,SLC1A2
1.101e-04	-9.11	CARM1 (coactivator associated arginine methyltransferase 1)	protein interactions	10498	304	6	19454	49	QKI,CTBP1,NCKAP5,RORA,PRKN,SNTB1
1.191e-04	-9.04	Pcbp1 (poly(rC) binding protein 1)	protein interactions	23983	38	3	19454	49	CTBP1,QKI,MSI2
1.279e-04	-8.96	positive regulation of multicellular organismal process	biological process	GO:0051240	1691	14	18204	50	ADGRB3,EGF,QKI,AMOT,PTN,PTPRZ1,PRDM16,GPM6B,RORA,GJA1,ZBTB20,SOX5,SLC39A12,ASPA
1.295e-04	-8.95	FGF5 (fibroblast growth factor 5)	protein interactions	2250	7	2	19454	49	EGF,FGFR3
1.320e-04	-8.93	autonomic_ganglia-neuroblastoma	COSMIC cancer mutations	autonomic_ganglia-neuroblastoma	3970	23	16828	47	PREX2,NFIA,FHOD3,SLC1A2,PRDM16,PREX1,FGFR3,GJA1,NCKAP5,AQP4,GPM6B,TRPS1,EGF,SNTB1,SLC4A4,USP6NL,TNS3,LPIN2,RFX4,AMOT,NPAS3,PTPRZ1,SORCS2
1.326e-04	-8.93	neuroblastoma	COSMIC cancer mutations	neuroblastoma	3971	23	16828	47	TRPS1,FHOD3,NFIA,GPM6B,PREX2,FGFR3,SLC4A4,PRDM16,PREX1,SNTB1,EGF,SLC1A2,TNS3,USP6NL,AQP4,SORCS2,NCKAP5,PTPRZ1,NPAS3,RFX4,AMOT,LPIN2,GJA1
1.352e-04	-8.91	regulation of multicellular organismal development	biological process	GO:2000026	1484	13	18204	50	ADGRB3,EGF,QKI,AMOT,TRPS1,PTN,PTPRZ1,GPM6B,GJA1,SOX5,LAMA4,SLC39A12,ASPA
1.427e-04	-8.85	regulation of carbohydrate metabolic process	biological process	GO:0006109	183	5	18204	50	EGF,ZBTB20,PRKN,RORA,SLC4A4
1.487e-04	-8.81	Na-dicarboxylate_symporter_CS	interpro domains	IPR018107	7	2	18521	50	SLC1A2,SLC1A3
1.487e-04	-8.81	Na:dicarbo_symporter_sf	interpro domains	IPR036458	7	2	18521	50	SLC1A3,SLC1A2
1.487e-04	-8.81	Na-dicarboxylate_symporter	interpro domains	IPR001991	7	2	18521	50	SLC1A2,SLC1A3
1.532e-04	-8.78	pancreas-carcinoid-endocrine_tumour	COSMIC cancer mutations	pancreas-carcinoid-endocrine_tumour	7250	33	16828	47	USP6NL,SLC1A3,SLC6A11,GPC5,TNS3,CTBP1,RFX4,ASPA,LRIG1,DGKB,SNTB1,EGF,GRK5,SLC4A4,FGFRL1,SOX5,FARP1,FKBP5,RORA,PTN,UNC93A,NHSL1,NCKAP5,QKI,BCAR3,FHOD3,PREX2,SLC1A2,ELOVL2,FGFR3,LAMA4,PREX1,PRDM16
1.551e-04	-8.77	Sodium:dicarboxylate symporter	gene3d domains	1.10.3860.10	7	2	14470	40	SLC1A3,SLC1A2
1.610e-04	-8.73	SDF	pfam domains	PF00375	7	2	17795	50	SLC1A3,SLC1A2
1.703e-04	-8.68	upper_aerodigestive_tract-larynx-carcinoma-squamous_cell_carcinoma	COSMIC cancer mutations	upper_aerodigestive_tract-larynx-carcinoma-squamous_cell_carcinoma	1946	15	16828	47	AMOT,NCKAP5,NPAS3,SORCS2,RORA,ZBTB20,PTN,SOX5,LAMA4,PREX1,SLC4A4,FGFR3,SLC39A12,DGKB,FHOD3
1.723e-04	-8.67	larynx	COSMIC cancer mutations	larynx	1948	15	16828	47	NPAS3,NCKAP5,AMOT,SORCS2,PTN,ZBTB20,RORA,SLC4A4,SLC39A12,FGFR3,PREX1,SOX5,LAMA4,DGKB,FHOD3
1.813e-04	-8.62	soft_tissue-blood_vessel-angiosarcoma	COSMIC cancer mutations	soft_tissue-blood_vessel-angiosarcoma	2192	16	16828	47	NCKAP5,PTPRZ1,SORCS2,FARP1,PTN,SLC1A3,GPC5,TNS3,SNTB1,SLC1A2,SLC39A12,SOX5,PRDM16,DGKB,FHOD3,PREX2
1.813e-04	-8.62	angiosarcoma	COSMIC cancer mutations	angiosarcoma	2192	16	16828	47	GPC5,TNS3,FARP1,PTN,SLC1A3,SORCS2,PTPRZ1,NCKAP5,FHOD3,PREX2,DGKB,SLC39A12,SOX5,PRDM16,SNTB1,SLC1A2
1.963e-04	-8.54	neural precursor cell proliferation	biological process	GO:0061351	105	4	18204	50	NFIA,SOX5,EGF,RORA
1.990e-04	-8.52	central_nervous_system-brain-primitive_neuroectodermal_tumour-medulloblastoma-large_cell	COSMIC cancer mutations	central_nervous_system-brain-primitive_neuroectodermal_tumour-medulloblastoma-large_cell	1117	11	16828	47	SORCS2,PRDM16,SOX5,QKI,NCKAP5,GRK5,SLC1A2,UNC93A,FHOD3,GPC5,DGKB
2.048e-04	-8.49	cell proliferation in hindbrain	biological process	GO:0021534	8	2	18204	50	RORA,EGF
2.048e-04	-8.49	cell proliferation in external granule layer	biological process	GO:0021924	8	2	18204	50	EGF,RORA
2.048e-04	-8.49	cerebellar granule cell precursor proliferation	biological process	GO:0021930	8	2	18204	50	EGF,RORA
2.071e-04	-8.48	cellular response to endogenous stimulus	biological process	GO:0071495	1135	11	18204	50	LPIN2,NFIA,BCAR3,SLC1A2,FGFRL1,FGFR3,APOA1,GJA1,SOX5,PRKN,SLC1A3
2.075e-04	-8.48	NA_DICARBOXYL_SYMP_2	prosite domains	PS00714	7	2	12186	39	SLC1A2,SLC1A3
2.075e-04	-8.48	NA_DICARBOXYL_SYMP_1	prosite domains	PS00713	7	2	12186	39	SLC1A3,SLC1A2
2.136e-04	-8.45	ELK3 (ETS transcription factor ELK3)	protein interactions	2004	117	4	19454	49	PRDM16,TRPS1,NFIA,CTBP1
2.212e-04	-8.42	SPEF2 (sperm flagellar 2)	protein interactions	79925	9	2	19454	49	PRKN,APOA1
2.329e-04	-8.37	EDTRNSPORT	prints domains	PR00173	7	2	5227	18	SLC1A2,SLC1A3
2.339e-04	-8.36	human chr6q26	chromosome location	human chr6q26	12	2	26134	50	PRKN,QKI
2.421e-04	-8.33	mixed_intestinal_and_diffuse_adenocarcinoma-unclassifiable	COSMIC cancer mutations	mixed_intestinal_and_diffuse_adenocarcinoma-unclassifiable	951	10	16828	47	PTN,PREX2,GPC5,UNC93A,SLC1A2,EGF,SNTB1,NCKAP5,PREX1,PRDM16
2.421e-04	-8.33	stomach-carcinoma-mixed_intestinal_and_diffuse_adenocarcinoma-unclassifiable	COSMIC cancer mutations	stomach-carcinoma-mixed_intestinal_and_diffuse_adenocarcinoma-unclassifiable	951	10	16828	47	PRDM16,PREX1,SLC1A2,SNTB1,NCKAP5,EGF,GPC5,PREX2,UNC93A,PTN
2.432e-04	-8.32	kidney-other-neoplasm	COSMIC cancer mutations	kidney-other-neoplasm	10653	41	16828	47	SLC1A2,ELOVL2,FGFR3,LAMA4,PREX1,PRDM16,APOA1,FHOD3,PREX2,NCKAP5,QKI,BCAR3,AQP4,FARP1,ZBTB20,RORA,FKBP5,PTN,UNC93A,NHSL1,SNTB1,EGF,GRK5,SLC39A12,SOX5,FGFRL1,LRIG1,DGKB,TRPS1,PTPRZ1,CTBP1,NPAS3,RFX4,LPIN2,ASPA,SORCS2,USP6NL,SLC1A3,SLC6A11,GPC5,TNS3
2.494e-04	-8.30	KLF3 (KLF transcription factor 3)	protein interactions	51274	225	5	19454	49	NFIA,PRDM16,TRPS1,CTBP1,SOX5
2.514e-04	-8.29	regulation of gliogenesis	biological process	GO:0014013	112	4	18204	50	PTPRZ1,ASPA,PTN,QKI
2.551e-04	-8.27	acidic amino acid transport	biological process	GO:0015800	45	3	18204	50	GJA1,SLC1A3,SLC1A2
2.629e-04	-8.24	negative regulation of neurotransmitter transport	biological process	GO:0051589	9	2	18204	50	PRKN,GPM6B
2.692e-04	-8.22	diffuse_large_B_cell_lymphoma	COSMIC cancer mutations	diffuse_large_B_cell_lymphoma	4151	23	16828	47	EGF,SNTB1,GRK5,SOX5,DGKB,TRPS1,SORCS2,SLC1A3,USP6NL,SLC6A11,TNS3,GPC5,SLC1A2,FGFR3,PRDM16,LAMA4,FHOD3,PREX2,QKI,NCKAP5,AQP4,FARP1,RORA
2.718e-04	-8.21	positive regulation of cellular process	biological process	GO:0048522	5719	28	18204	50	SLC1A3,ASPA,ZBTB20,GJA1,APOA1,PRDM16,PTPRZ1,PTN,RFX4,CTBP1,SLC4A4,BCAR3,SLC1A2,GPC5,LPIN2,EGF,FARP1,PRKN,SOX5,PREX1,RORA,GRK5,PLPP3,FGFR3,NPAS3,NFIA,ADGRB3,QKI
2.736e-04	-8.20	regulation of developmental process	biological process	GO:0050793	2540	17	18204	50	ADGRB3,EGF,QKI,PTN,TRPS1,AMOT,GPM6B,PTPRZ1,FGFR3,ASPA,SLC39A12,PREX1,PRKN,SOX5,LAMA4,RORA,GJA1
2.796e-04	-8.18	NRAS (NRAS proto-oncogene, GTPase)	protein interactions	4893	683	8	19454	49	USP6NL,SLC39A12,GJA1,PREX1,FARP1,FGFRL1,PLPP3,SLC1A3
2.802e-04	-8.18	enzyme-linked receptor protein signaling pathway	biological process	GO:0007167	626	8	18204	50	APOA1,PTN,FGFR3,EGF,FGFRL1,FARP1,BCAR3,NFIA
2.877e-04	-8.15	positive regulation of developmental process	biological process	GO:0051094	1385	12	18204	50	PTN,AMOT,ADGRB3,EGF,QKI,ASPA,SLC39A12,PRKN,SOX5,GJA1,GPM6B,PTPRZ1
2.917e-04	-8.14	GTPase regulator activity	molecular function	GO:0030695	491	7	18094	48	ADGRB3,BCAR3,USP6NL,PREX2,EGF,FARP1,PREX1
2.917e-04	-8.14	nucleoside-triphosphatase regulator activity	molecular function	GO:0060589	491	7	18094	48	PREX2,USP6NL,BCAR3,ADGRB3,PREX1,FARP1,EGF
2.990e-04	-8.12	ear	COSMIC cancer mutations	ear	624	8	16828	47	NPAS3,GRK5,FGFR3,LAMA4,FGFRL1,ZBTB20,SLC6A11,UNC93A
3.042e-04	-8.10	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-diffuse_large_B_cell_lymphoma	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-diffuse_large_B_cell_lymphoma	3608	21	16828	47	EGF,SNTB1,GRK5,SLC1A2,FGFR3,PRDM16,SOX5,LAMA4,DGKB,FHOD3,PREX2,QKI,NCKAP5,AQP4,SORCS2,FARP1,RORA,USP6NL,SLC6A11,TNS3,GPC5
3.043e-04	-8.10	FGF2 (fibroblast growth factor 2)	protein interactions	2247	52	3	19454	49	FGFRL1,PRKN,FGFR3
3.043e-04	-8.10	ABCA1 (ATP binding cassette subfamily A member 1)	protein interactions	19	52	3	19454	49	APOA1,SNTB1,PRKN
3.143e-04	-8.07	lymphoid_neoplasm	COSMIC cancer mutations	lymphoid_neoplasm	12233	44	16828	47	TRPS1,DGKB,LRIG1,SLC4A4,SOX5,FGFRL1,SNTB1,SLC6A11,ASPA,SORCS2,NPAS3,AMOT,FHOD3,FGFR3,ELOVL2,PREX1,LAMA4,SLC1A2,UNC93A,NHSL1,FKBP5,ZBTB20,AQP4,QKI,NCKAP5,SLC39A12,EGF,GRK5,TNS3,GPC5,SLC1A3,USP6NL,MSI2,CTBP1,PTPRZ1,LPIN2,RFX4,PREX2,NFIA,PRDM16,FARP1,PTN,RORA,BCAR3
3.155e-04	-8.06	plasma membrane region	cellular component	GO:0098590	1278	11	19108	49	DGKB,PLPP3,ADGRB3,SORCS2,SLC1A3,SLC1A2,FARP1,SLC6A11,GJA1,AQP4,SLC4A4
3.212e-04	-8.04	upper_aerodigestive_tract-mouth-carcinoma	COSMIC cancer mutations	upper_aerodigestive_tract-mouth-carcinoma	6426	30	16828	47	TNS3,GPC5,SLC1A3,USP6NL,SORCS2,CTBP1,NPAS3,RFX4,TRPS1,DGKB,SLC4A4,SLC39A12,SOX5,EGF,SNTB1,GRK5,UNC93A,NHSL1,ZBTB20,RORA,QKI,NCKAP5,FHOD3,PREX2,APOA1,FGFR3,PREX1,PRDM16,LAMA4,SLC1A2
3.281e-04	-8.02	cellular response to cocaine	biological process	GO:0071314	10	2	18204	50	SLC1A3,SLC1A2
3.349e-04	-8.00	guanyl-nucleotide exchange factor activity	molecular function	GO:0005085	228	5	18094	48	PREX2,BCAR3,PREX1,FARP1,EGF
3.689e-04	-7.91	FOXP1 (forkhead box P1)	protein interactions	27086	135	4	19454	49	PRKN,NFIA,SOX5,CTBP1
3.833e-04	-7.87	Neurotransmitter Release Cycle	REACTOME pathways	R-HSA-112310	51	3	10285	29	SLC1A3,SLC6A11,SLC1A2
3.977e-04	-7.83	PRNP (prion protein (Kanno blood group))	protein interactions	5621	1118	10	19454	49	MSI2,PTPRZ1,SLC4A4,NHSL1,GJA1,QKI,ASPA,AQP4,SLC1A3,TRPS1
3.992e-04	-7.83	cervix-carcinoma-squamous_cell_carcinoma	COSMIC cancer mutations	cervix-carcinoma-squamous_cell_carcinoma	11789	43	16828	47	QKI,NCKAP5,BCAR3,GJA1,FARP1,RORA,ZBTB20,FKBP5,UNC93A,NHSL1,SLC1A2,FGFR3,ELOVL2,PREX1,PRDM16,LAMA4,FHOD3,PREX2,NFIA,NPAS3,CTBP1,PTPRZ1,RFX4,AMOT,LPIN2,ASPA,SORCS2,SLC1A3,USP6NL,SLC6A11,TNS3,GPC5,EGF,SNTB1,GRK5,SLC4A4,SLC39A12,SOX5,FGFRL1,DGKB,LRIG1,TRPS1,GPM6B
4.003e-04	-7.82	L-glutamate import across plasma membrane	biological process	GO:0098712	11	2	18204	50	SLC1A3,SLC1A2
4.003e-04	-7.82	L-aspartate transmembrane transport	biological process	GO:0070778	11	2	18204	50	SLC1A3,SLC1A2
4.010e-04	-7.82	NFIB (nuclear factor I B)	protein interactions	4781	138	4	19454	49	NFIA,GRK5,TRPS1,SOX5
4.039e-04	-7.81	cervix	COSMIC cancer mutations	cervix	11793	43	16828	47	SORCS2,ASPA,AMOT,LPIN2,RFX4,PTPRZ1,NPAS3,CTBP1,GPC5,TNS3,SLC6A11,USP6NL,SLC1A3,FGFRL1,SOX5,SLC4A4,SLC39A12,GRK5,SNTB1,EGF,GPM6B,TRPS1,LRIG1,DGKB,BCAR3,GJA1,NCKAP5,QKI,NHSL1,UNC93A,ZBTB20,FKBP5,RORA,FARP1,LAMA4,PRDM16,PREX1,ELOVL2,FGFR3,SLC1A2,NFIA,PREX2,FHOD3
4.198e-04	-7.78	CRX (cone-rod homeobox)	protein interactions	1406	252	5	19454	49	TRPS1,PRDM16,PRKN,NFIA,SOX5
4.198e-04	-7.78	human chr4p16.3	chromosome location	human chr4p16.3	76	3	26134	50	FGFR3,FGFRL1,CTBP1
4.350e-04	-7.74	SNTB2 (syntrophin beta 2)	protein interactions	6645	141	4	19454	49	SNTB1,FGFR3,PRKN,TNS3
4.588e-04	-7.69	BAZ1A (bromodomain adjacent to zinc finger domain 1A)	protein interactions	11177	143	4	19454	49	CTBP1,PRKN,FGFR3,GRK5
4.698e-04	-7.66	amino acid transport	biological process	GO:0006865	132	4	18204	50	SLC1A2,SLC1A3,GJA1,SLC6A11
4.752e-04	-7.65	pleura	COSMIC cancer mutations	pleura	4914	25	16828	47	GRK5,SNTB1,FGFRL1,SOX5,LRIG1,DGKB,GPM6B,TRPS1,AMOT,LPIN2,PTPRZ1,MSI2,USP6NL,LAMA4,PREX1,PRDM16,FGFR3,PREX2,FHOD3,BCAR3,NCKAP5,QKI,FKBP5,RORA,FARP1
4.763e-04	-7.65	PLEKHH1 (pleckstrin homology, MyTH4 and FERM domain containing H1)	protein interactions	57475	13	2	19454	49	FKBP5,PRKN
4.833e-04	-7.63	face	COSMIC cancer mutations	face	2139	15	16828	47	PTPRZ1,AQP4,MSI2,FARP1,RORA,SLC6A11,GPC5,EGF,GRK5,FGFR3,PRDM16,LAMA4,FHOD3,TRPS1,PREX2
4.877e-04	-7.63	TSPAN10 (tetraspanin 10)	protein interactions	83882	61	3	19454	49	PRKN,GJA1,ELOVL2
5.132e-04	-7.57	sulfur compound transmembrane transporter activity	molecular function	GO:1901682	59	3	18094	48	SLC1A2,SLC6A11,GJA1
5.276e-04	-7.55	monoatomic cation:bicarbonate symporter activity	molecular function	GO:0140410	13	2	18094	48	SLC39A12,SLC4A4
5.297e-04	-7.54	synaptic membrane	cellular component	GO:0097060	400	6	19108	49	SLC1A2,FARP1,SLC6A11,SORCS2,ADGRB3,DGKB
5.558e-04	-7.50	upper_aerodigestive_tract-mouth-carcinoma-squamous_cell_carcinoma	COSMIC cancer mutations	upper_aerodigestive_tract-mouth-carcinoma-squamous_cell_carcinoma	6953	31	16828	47	SLC1A2,LAMA4,PREX1,PRDM16,ELOVL2,FGFR3,APOA1,PREX2,FHOD3,BCAR3,NCKAP5,QKI,ZBTB20,RORA,PTN,NHSL1,UNC93A,GRK5,SNTB1,SOX5,SLC4A4,SLC39A12,LRIG1,DGKB,TRPS1,RFX4,PTPRZ1,SORCS2,USP6NL,GPC5,TNS3
5.775e-04	-7.46	ARFGAP2 (ADP ribosylation factor GTPase activating protein 2)	protein interactions	84364	152	4	19454	49	PRKN,BCAR3,GJA1,CTBP1
5.865e-04	-7.44	neurotransmitter transport	biological process	GO:0006836	140	4	18204	50	PRKN,SLC6A11,SLC1A2,SLC1A3
6.032e-04	-7.41	ERBB2 (erb-b2 receptor tyrosine kinase 2)	protein interactions	2064	583	7	19454	49	EGF,FGFR3,GJA1,BCAR3,TNS3,GPM6B,LRIG1
6.037e-04	-7.41	astrocytoma_Grade_I	COSMIC cancer mutations	astrocytoma_Grade_I	139	4	16828	47	FGFR3,PRDM16,GPC5,QKI
6.093e-04	-7.40	neuron differentiation	biological process	GO:0030182	1081	10	18204	50	PTPRZ1,NFIA,GPM6B,FARP1,ADGRB3,SLC39A12,PTN,SLC1A3,PREX2,RORA
6.145e-04	-7.39	phosphatidate phosphatase activity	molecular function	GO:0008195	14	2	18094	48	LPIN2,PLPP3
6.145e-04	-7.39	L-glutamate transmembrane transporter activity	molecular function	GO:0005313	14	2	18094	48	SLC1A2,SLC1A3
6.354e-04	-7.36	serous_carcinoma	COSMIC cancer mutations	serous_carcinoma	10987	41	16828	47	NPAS3,CTBP1,PTPRZ1,LPIN2,AMOT,MSI2,ASPA,SORCS2,SLC1A3,USP6NL,SLC6A11,TNS3,GPC5,EGF,SNTB1,GRK5,SLC39A12,SLC4A4,SOX5,FGFRL1,DGKB,LRIG1,TRPS1,GPM6B,QKI,NCKAP5,GJA1,BCAR3,FARP1,FKBP5,RORA,ZBTB20,NHSL1,SLC1A2,FGFR3,ELOVL2,PRDM16,PREX1,LAMA4,FHOD3,PREX2
6.579e-04	-7.33	sulfur compound transport	biological process	GO:0072348	62	3	18204	50	SLC1A2,GJA1,SLC6A11
6.985e-04	-7.27	cell development	biological process	GO:0048468	2236	15	18204	50	FHOD3,PTPRZ1,GPM6B,RORA,GJA1,PREX1,SLC39A12,MSI2,SLC1A3,ASPA,FARP1,QKI,ADGRB3,PREX2,PTN
7.220e-04	-7.23	dendrite morphogenesis	biological process	GO:0048813	64	3	18204	50	FARP1,PTN,PREX2
7.292e-04	-7.22	HLA-H (major histocompatibility complex, class I, H (pseudogene))	protein interactions	3136	16	2	19454	49	PRKN,FGFR3
7.339e-04	-7.22	postsynaptic membrane	cellular component	GO:0045211	280	5	19108	49	FARP1,SLC6A11,SORCS2,ADGRB3,DGKB
7.414e-04	-7.21	organic anion transport	biological process	GO:0015711	398	6	18204	50	SLC6A11,GJA1,SLC4A4,SLC39A12,SLC1A3,SLC1A2
7.426e-04	-7.21	humerus	COSMIC cancer mutations	humerus	546	7	16828	47	GPC5,FHOD3,FARP1,SOX5,LAMA4,NCKAP5,EGF
7.504e-04	-7.19	MTA3 (metastasis associated 1 family member 3)	protein interactions	57504	163	4	19454	49	TRPS1,PRKN,BCAR3,SOX5
7.604e-04	-7.18	bone	COSMIC cancer mutations	bone	8157	34	16828	47	UNC93A,RORA,ZBTB20,FARP1,QKI,NCKAP5,PREX2,FHOD3,PRDM16,PREX1,LAMA4,FGFR3,ELOVL2,TNS3,GPC5,SLC6A11,SLC1A3,USP6NL,SORCS2,ASPA,LPIN2,NPAS3,PTPRZ1,GPM6B,TRPS1,DGKB,LRIG1,SOX5,FGFRL1,SLC39A12,SLC4A4,GRK5,EGF,SNTB1
7.721e-04	-7.17	active monoatomic ion transmembrane transporter activity	molecular function	GO:0022853	274	5	18094	48	SLC6A11,SLC39A12,SLC1A2,SLC1A3,SLC4A4
7.789e-04	-7.16	regulation of cold-induced thermogenesis	biological process	GO:0120161	151	4	18204	50	QKI,LAMA4,GJA1,PRDM16
7.853e-04	-7.15	EGR2 (early growth response 2)	protein interactions	1959	165	4	19454	49	SOX5,PRDM16,TRPS1,NFIA
7.930e-04	-7.14	BCOR (BCL6 corepressor)	protein interactions	54880	290	5	19454	49	NFIA,PRKN,CTBP1,AMOT,SOX5
7.953e-04	-7.14	Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour	COSMIC cancer mutations	Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour	7434	32	16828	47	NCKAP5,QKI,ZBTB20,RORA,FARP1,UNC93A,LAMA4,PREX1,PRDM16,ELOVL2,FGFR3,PREX2,FHOD3,LPIN2,PTPRZ1,NPAS3,SORCS2,ASPA,USP6NL,SLC1A3,TNS3,SLC6A11,GRK5,SNTB1,EGF,SOX5,FGFRL1,SLC4A4,SLC39A12,LRIG1,GPM6B,TRPS1
8.055e-04	-7.12	oligoastrocytoma_Grade_III	COSMIC cancer mutations	oligoastrocytoma_Grade_III	263	5	16828	47	FGFR3,SOX5,PREX2,AMOT,SLC1A2
8.077e-04	-7.12	sodium ion transmembrane transporter activity	molecular function	GO:0015081	158	4	18094	48	SLC1A2,SLC6A11,SLC1A3,SLC4A4
8.923e-04	-7.02	DH-domain	interpro domains	IPR000219	70	3	18521	50	FARP1,PREX2,PREX1
9.299e-04	-6.98	DBL_dom_sf	interpro domains	IPR035899	71	3	18521	50	PREX1,PREX2,FARP1
9.320e-04	-6.98	Signaling by MET	REACTOME pathways	R-HSA-6806834	69	3	10285	29	LAMA4,TNS3,LRIG1
9.508e-04	-6.96	Glycerolipid metabolism	KEGG pathways	hsa00561	59	3	7161	24	PLPP3,LPIN2,DGKB
9.508e-04	-6.96	Glycerolipid metabolism	KEGG pathways	ko00561	59	3	7161	24	DGKB,PLPP3,LPIN2
9.571e-04	-6.95	NME2 (NME/NM23 nucleoside diphosphate kinase 2)	protein interactions	4831	174	4	19454	49	PREX1,RORA,PRKN,CTBP1
9.685e-04	-6.94	skin-face-carcinoma-squamous_cell_carcinoma	COSMIC cancer mutations	skin-face-carcinoma-squamous_cell_carcinoma	2036	14	16828	47	GRK5,EGF,PTPRZ1,PRDM16,LAMA4,FGFR3,AQP4,MSI2,RORA,FARP1,PREX2,GPC5,FHOD3,TRPS1
9.794e-04	-6.93	viral genome replication	biological process	GO:0019079	17	2	18204	50	CTBP1,NFIA
9.804e-04	-6.93	secondary active transmembrane transporter activity	molecular function	GO:0015291	289	5	18094	48	SLC4A4,SLC1A3,SLC1A2,SLC39A12,SLC6A11
9.819e-04	-6.93	Dbl homology (DH) domain	gene3d domains	1.20.900.10	71	3	14470	40	FARP1,PREX1,PREX2
1.001e-03	-6.91	RhoGEF	pfam domains	PF00621	70	3	17795	50	PREX1,FARP1,PREX2
1.025e-03	-6.88	ovary-carcinoma-serous_carcinoma	COSMIC cancer mutations	ovary-carcinoma-serous_carcinoma	10710	40	16828	47	SLC39A12,SLC4A4,SOX5,FGFRL1,SNTB1,GRK5,TRPS1,GPM6B,LRIG1,DGKB,MSI2,ASPA,SORCS2,PTPRZ1,CTBP1,NPAS3,AMOT,LPIN2,SLC6A11,GPC5,TNS3,USP6NL,SLC1A3,ELOVL2,FGFR3,LAMA4,PRDM16,PREX1,SLC1A2,FHOD3,PREX2,NCKAP5,QKI,GJA1,BCAR3,NHSL1,FARP1,ZBTB20,RORA,FKBP5
1.026e-03	-6.88	acidic amino acid transmembrane transporter activity	molecular function	GO:0015172	18	2	18094	48	SLC1A3,SLC1A2
1.029e-03	-6.88	striated_muscle	COSMIC cancer mutations	striated_muscle	4228	22	16828	47	NFIA,PREX2,TRPS1,FHOD3,DGKB,FGFRL1,PRDM16,ELOVL2,FGFR3,GRK5,EGF,NHSL1,RORA,USP6NL,SLC1A3,SORCS2,AQP4,GJA1,NCKAP5,PTPRZ1,NPAS3,CTBP1
1.033e-03	-6.88	regulation of multicellular organismal process	biological process	GO:0051239	3113	18	18204	50	PRDM16,GPM6B,PTPRZ1,PLPP3,ASPA,SLC39A12,SOX5,ZBTB20,LAMA4,APOA1,RORA,GJA1,ADGRB3,EGF,QKI,PTN,TRPS1,AMOT
1.041e-03	-6.87	ERBB4 (erb-b2 receptor tyrosine kinase 4)	protein interactions	2066	178	4	19454	49	GJA1,BCAR3,TNS3,LRIG1
1.046e-03	-6.86	MCAM (melanoma cell adhesion molecule)	protein interactions	4162	464	6	19454	49	GJA1,FARP1,SNTB1,LAMA4,PLPP3,USP6NL
1.071e-03	-6.84	astrocyte projection	cellular component	GO:0097449	19	2	19108	49	AQP4,SLC1A2
1.085e-03	-6.83	EPHA4 (EPH receptor A4)	protein interactions	2043	180	4	19454	49	USP6NL,TNS3,GJA1,FGFR3
1.145e-03	-6.77	lipid phosphatase activity	molecular function	GO:0042577	19	2	18094	48	PLPP3,LPIN2
1.156e-03	-6.76	LRRC40 (leucine rich repeat containing 40)	protein interactions	55631	82	3	19454	49	PRKN,LRIG1,FKBP5
1.201e-03	-6.72	KLF12 (KLF transcription factor 12)	protein interactions	11278	185	4	19454	49	TRPS1,PRDM16,NFIA,CTBP1
1.227e-03	-6.70	regulation of neurotransmitter uptake	biological process	GO:0051580	19	2	18204	50	GPM6B,PRKN
1.235e-03	-6.70	response to endogenous stimulus	biological process	GO:0009719	1402	11	18204	50	NFIA,SLC1A2,BCAR3,LPIN2,SLC1A3,SOX5,PRKN,APOA1,GJA1,FGFR3,FGFRL1
1.240e-03	-6.69	FXYD6 (FXYD domain containing ion transport regulator 6)	protein interactions	53826	84	3	19454	49	GPC5,SLC39A12,ELOVL2
1.240e-03	-6.69	MAPK12 (mitogen-activated protein kinase 12)	protein interactions	6300	84	3	19454	49	SNTB1,PRKN,FKBP5
1.280e-03	-6.66	positive regulation of nervous system development	biological process	GO:0051962	296	5	18204	50	PTPRZ1,ASPA,PTN,QKI,ADGRB3
1.283e-03	-6.66	positive regulation of carbohydrate metabolic process	biological process	GO:0045913	78	3	18204	50	SLC4A4,ZBTB20,EGF
1.283e-03	-6.66	dicarboxylic acid transport	biological process	GO:0006835	78	3	18204	50	GJA1,SLC1A2,SLC1A3
1.285e-03	-6.66	prostate	COSMIC cancer mutations	prostate	13883	46	16828	47	SLC6A11,NPAS3,ASPA,SORCS2,LRIG1,DGKB,TRPS1,GPM6B,SNTB1,SLC4A4,SOX5,FGFRL1,FKBP5,ZBTB20,UNC93A,NHSL1,NCKAP5,QKI,GJA1,AQP4,APOA1,FHOD3,SLC1A2,ELOVL2,FGFR3,LAMA4,PREX1,USP6NL,SLC1A3,GPC5,TNS3,PTPRZ1,CTBP1,RFX4,LPIN2,MSI2,EGF,GRK5,SLC39A12,FARP1,RORA,PTN,BCAR3,NFIA,PREX2,PRDM16
1.343e-03	-6.61	lung-right_upper_lobe-carcinoma-adenocarcinoma	COSMIC cancer mutations	lung-right_upper_lobe-carcinoma-adenocarcinoma	10376	39	16828	47	APOA1,PREX2,NFIA,FHOD3,SLC1A2,PREX1,PRDM16,LAMA4,FGFR3,ELOVL2,PTN,ZBTB20,RORA,FARP1,UNC93A,BCAR3,NCKAP5,DGKB,LRIG1,GPM6B,TRPS1,GRK5,EGF,SOX5,FGFRL1,SLC39A12,SLC4A4,SLC1A3,USP6NL,TNS3,GPC5,SLC6A11,RFX4,AMOT,LPIN2,CTBP1,NPAS3,PTPRZ1,SORCS2
1.343e-03	-6.61	right_upper_lobe	COSMIC cancer mutations	right_upper_lobe	10376	39	16828	47	SLC1A2,LAMA4,PRDM16,PREX1,ELOVL2,FGFR3,APOA1,NFIA,PREX2,FHOD3,BCAR3,NCKAP5,ZBTB20,RORA,PTN,FARP1,UNC93A,GRK5,EGF,FGFRL1,SOX5,SLC39A12,SLC4A4,LRIG1,DGKB,GPM6B,TRPS1,AMOT,RFX4,LPIN2,PTPRZ1,NPAS3,CTBP1,SORCS2,USP6NL,SLC1A3,GPC5,TNS3,SLC6A11
1.354e-03	-6.60	APC (APC regulator of WNT signaling pathway)	protein interactions	324	327	5	19454	49	GJA1,NCKAP5,AMOT,CTBP1,LAMA4
1.361e-03	-6.60	aspartate transmembrane transport	biological process	GO:0015810	20	2	18204	50	SLC1A3,SLC1A2
1.377e-03	-6.59	scalp	COSMIC cancer mutations	scalp	2110	14	16828	47	PREX1,LAMA4,SOX5,SLC4A4,FGFR3,PREX2,NFIA,TRPS1,PTPRZ1,PTN,RORA,FARP1,GPC5,SLC6A11
1.390e-03	-6.58	Dusp14 (dual specificity phosphatase 14)	protein interactions	56405	22	2	19454	49	CTBP1,QKI
1.404e-03	-6.57	MED1 (mediator complex subunit 1)	protein interactions	5469	193	4	19454	49	QKI,CTBP1,RORA,PRKN
1.410e-03	-6.56	LGALS3 (galectin 3)	protein interactions	3958	330	5	19454	49	PTPRZ1,LAMA4,PRKN,SLC1A3,APOA1
1.425e-03	-6.55	behavior	biological process	GO:0007610	619	7	18204	50	SLC1A2,PTPRZ1,ADGRB3,SLC1A3,PREX2,PTN,PRKN
1.431e-03	-6.55	DH_2	prosite domains	PS50010	70	3	12186	39	FARP1,PREX2,PREX1
1.452e-03	-6.54	GDS_CDC24_CS	interpro domains	IPR001331	21	2	18521	50	PREX2,PREX1
1.482e-03	-6.51	regulation of bone mineralization	biological process	GO:0030500	82	3	18204	50	GJA1,GPM6B,PTN
1.501e-03	-6.50	central_nervous_system-brain-glioma-astrocytoma_Grade_III	COSMIC cancer mutations	central_nervous_system-brain-glioma-astrocytoma_Grade_III	1419	11	16828	47	PRDM16,FGFR3,SLC39A12,GRK5,BCAR3,SNTB1,NCKAP5,GPC5,TNS3,FHOD3,FARP1
1.502e-03	-6.50	positive regulation of nucleotide catabolic process	biological process	GO:0030813	21	2	18204	50	SLC4A4,ZBTB20
1.502e-03	-6.50	positive regulation of purine nucleotide catabolic process	biological process	GO:0033123	21	2	18204	50	SLC4A4,ZBTB20
1.502e-03	-6.50	positive regulation of stem cell differentiation	biological process	GO:2000738	21	2	18204	50	PTN,SOX5
1.502e-03	-6.50	positive regulation of glycolytic process	biological process	GO:0045821	21	2	18204	50	ZBTB20,SLC4A4
1.520e-03	-6.49	SIM2 (SIM bHLH transcription factor 2)	protein interactions	6493	23	2	19454	49	PRKN,PREX1
1.520e-03	-6.49	Rbm38 (RNA binding motif protein 38)	protein interactions	56190	23	2	19454	49	MSI2,QKI
1.526e-03	-6.49	FAM120A (family with sequence similarity 120 member A)	protein interactions	23196	336	5	19454	49	PRDM16,GRK5,PRKN,FKBP5,QKI
1.570e-03	-6.46	DEP	pfam domains	PF00610	21	2	17795	50	PREX2,PREX1
1.594e-03	-6.44	DEP_dom	interpro domains	IPR000591	22	2	18521	50	PREX1,PREX2
1.644e-03	-6.41	oligodendrocyte differentiation	biological process	GO:0048709	85	3	18204	50	PTPRZ1,GPM6B,ASPA
1.662e-03	-6.40	DMRTB1 (DMRT like family B with proline rich C-terminal 1)	protein interactions	63948	93	3	19454	49	QKI,CTBP1,MSI2
1.668e-03	-6.40	positive regulation of hydrolase activity	biological process	GO:0051345	466	6	18204	50	BCAR3,FGFR3,PREX2,USP6NL,APOA1,PREX1
1.676e-03	-6.39	bone-femur-other-chondroblastoma	COSMIC cancer mutations	bone-femur-other-chondroblastoma	183	4	16828	47	GPC5,PREX1,NCKAP5,SNTB1
1.680e-03	-6.39	RhoGEF	smart domains	SM00325	68	3	9717	34	FARP1,PREX2,PREX1
1.683e-03	-6.39	fibroblast growth factor binding	molecular function	GO:0017134	23	2	18094	48	FGFRL1,FGFR3
1.700e-03	-6.38	transport across blood-brain barrier	biological process	GO:0150104	86	3	18204	50	SLC4A4,SLC1A2,SLC1A3
1.700e-03	-6.38	vascular transport	biological process	GO:0010232	86	3	18204	50	SLC1A2,SLC1A3,SLC4A4
1.713e-03	-6.37	diffuse_adenocarcinoma	COSMIC cancer mutations	diffuse_adenocarcinoma	4383	22	16828	47	PREX2,TRPS1,FHOD3,DGKB,LAMA4,SOX5,PREX1,ELOVL2,SLC39A12,FGFR3,SNTB1,NHSL1,SLC6A11,FKBP5,PTN,SLC1A3,FARP1,SORCS2,RFX4,NCKAP5,PTPRZ1,QKI
1.713e-03	-6.37	stomach-carcinoma-diffuse_adenocarcinoma	COSMIC cancer mutations	stomach-carcinoma-diffuse_adenocarcinoma	4383	22	16828	47	FGFR3,SLC39A12,ELOVL2,PREX1,LAMA4,SOX5,SNTB1,FHOD3,TRPS1,PREX2,DGKB,SORCS2,QKI,NCKAP5,PTPRZ1,RFX4,SLC6A11,NHSL1,FARP1,PTN,SLC1A3,FKBP5
1.714e-03	-6.37	WWC1 (WW and C2 domain containing 1)	protein interactions	23286	94	3	19454	49	USP6NL,AMOT,PRKN
1.751e-03	-6.35	UTRN (utrophin)	protein interactions	7402	205	4	19454	49	FGFR3,SNTB1,GJA1,TNS3
1.797e-03	-6.32	DDX59 (DEAD-box helicase 59)	protein interactions	83479	25	2	19454	49	FKBP5,PRKN
1.820e-03	-6.31	KCTD5 (potassium channel tetramerization domain containing 5)	protein interactions	54442	96	3	19454	49	GRK5,PRKN,GJA1
1.846e-03	-6.29	GATAD2A (GATA zinc finger domain containing 2A)	protein interactions	54815	208	4	19454	49	SOX5,TRPS1,PRDM16,PRKN
1.861e-03	-6.29	skin-face-malignant_melanoma-lentigo_maligna	COSMIC cancer mutations	skin-face-malignant_melanoma-lentigo_maligna	23	2	16828	47	FGFR3,PREX2
1.868e-03	-6.28	pharynx	COSMIC cancer mutations	pharynx	2696	16	16828	47	SORCS2,RFX4,NPAS3,QKI,PTPRZ1,NCKAP5,GPC5,NHSL1,FGFRL1,SLC4A4,SLC39A12,FGFR3,SLC1A2,EGF,PREX2,NFIA
1.871e-03	-6.28	CTBP2 (C-terminal binding protein 2)	protein interactions	1488	352	5	19454	49	MSI2,CTBP1,PRDM16,TRPS1,PRKN
1.894e-03	-6.27	ESYT2 (extended synaptotagmin 2)	protein interactions	57488	353	5	19454	49	PRKN,ELOVL2,GJA1,FARP1,USP6NL
1.906e-03	-6.26	oesophagus-middle_third-carcinoma-squamous_cell_carcinoma	COSMIC cancer mutations	oesophagus-middle_third-carcinoma-squamous_cell_carcinoma	3531	19	16828	47	SORCS2,PTPRZ1,BCAR3,UNC93A,NHSL1,GPC5,TNS3,FARP1,ZBTB20,FKBP5,SLC4A4,SLC39A12,LAMA4,SOX5,PRDM16,GRK5,FHOD3,PREX2,LRIG1
1.913e-03	-6.26	human chr6q12-q13	chromosome location	human chr6q12-q13	1	1	26134	50	ADGRB3
1.920e-03	-6.26	middle_third	COSMIC cancer mutations	middle_third	3533	19	16828	47	UNC93A,GPC5,NHSL1,TNS3,FARP1,ZBTB20,FKBP5,SORCS2,PTPRZ1,BCAR3,FHOD3,PREX2,LRIG1,SLC39A12,SLC4A4,LAMA4,SOX5,PRDM16,GRK5
1.928e-03	-6.25	anchoring junction	cellular component	GO:0070161	902	8	19108	49	PLPP3,AMOT,FGFR3,FGFRL1,TNS3,SNTB1,BCAR3,GJA1
1.931e-03	-6.25	PSMF1 (proteasome inhibitor subunit 1)	protein interactions	9491	98	3	19454	49	QKI,CTBP1,PRKN
1.942e-03	-6.24	TLE3 (TLE family member 3, transcriptional corepressor)	protein interactions	7090	355	5	19454	49	NFIA,PRKN,TRPS1,QKI,FKBP5
1.943e-03	-6.24	ZNF750 (zinc finger protein 750)	protein interactions	79755	26	2	19454	49	CTBP1,PRKN
1.943e-03	-6.24	TSSK2 (testis specific serine kinase 2)	protein interactions	23617	26	2	19454	49	APOA1,FKBP5
1.943e-03	-6.24	AP3M2 (adaptor related protein complex 3 subunit mu 2)	protein interactions	10947	26	2	19454	49	PRKN,GRK5
2.013e-03	-6.21	ANKFY1 (ankyrin repeat and FYVE domain containing 1)	protein interactions	51479	213	4	19454	49	FARP1,GRK5,PRKN,CTBP1
2.013e-03	-6.21	AP1M1 (adaptor related protein complex 1 subunit mu 1)	protein interactions	8907	213	4	19454	49	BCAR3,PRDM16,PRKN,AMOT
2.017e-03	-6.21	DH_1	prosite domains	PS00741	21	2	12186	39	PREX1,PREX2
2.017e-03	-6.21	DEP	prosite domains	PS50186	21	2	12186	39	PREX2,PREX1
2.031e-03	-6.20	CTNNB1 (catenin beta 1)	protein interactions	1499	926	8	19454	49	PRKN,PTN,NHSL1,GJA1,CTBP1,PTPRZ1,USP6NL,AMOT
2.039e-03	-6.20	Glutamate Neurotransmitter Release Cycle	REACTOME pathways	R-HSA-210500	24	2	10285	29	SLC1A2,SLC1A3
2.090e-03	-6.17	regulation of small molecule metabolic process	biological process	GO:0062012	331	5	18204	50	PRKN,ZBTB20,APOA1,SLC4A4,RORA
2.095e-03	-6.17	ARMCX5 (armadillo repeat containing X-linked 5)	protein interactions	64860	27	2	19454	49	FKBP5,PRKN
2.130e-03	-6.15	rhabdomyosarcoma	COSMIC cancer mutations	rhabdomyosarcoma	4150	21	16828	47	DGKB,PREX2,NFIA,FHOD3,TRPS1,GRK5,PRDM16,FGFRL1,FGFR3,ELOVL2,SLC1A3,RORA,USP6NL,NHSL1,GJA1,NPAS3,CTBP1,NCKAP5,PTPRZ1,SORCS2,AQP4
2.130e-03	-6.15	L-glutamate transmembrane transport	biological process	GO:0015813	25	2	18204	50	SLC1A2,SLC1A3
2.155e-03	-6.14	pancreas-carcinoma	COSMIC cancer mutations	pancreas-carcinoma	14770	47	16828	47	AQP4,GJA1,NCKAP5,QKI,NHSL1,UNC93A,FKBP5,ZBTB20,LAMA4,PREX1,ELOVL2,FGFR3,SLC1A2,FHOD3,APOA1,SORCS2,ASPA,AMOT,NPAS3,SLC6A11,FGFRL1,SOX5,SLC4A4,SNTB1,GPM6B,TRPS1,LRIG1,DGKB,BCAR3,RORA,PTN,FARP1,PRDM16,NFIA,PREX2,MSI2,RFX4,LPIN2,PTPRZ1,CTBP1,GPC5,TNS3,USP6NL,SLC1A3,SLC39A12,GRK5,EGF
2.164e-03	-6.14	PATJ (PATJ crumbs cell polarity complex component)	protein interactions	10207	102	3	19454	49	PRKN,PRDM16,AMOT
2.195e-03	-6.12	neuron development	biological process	GO:0048666	859	8	18204	50	PTPRZ1,SLC39A12,SLC1A3,PREX2,PTN,GPM6B,FARP1,ADGRB3
2.253e-03	-6.10	SYT11 (synaptotagmin 11)	protein interactions	23208	28	2	19454	49	PRKN,ZBTB20
2.253e-03	-6.10	RCOR2 (REST corepressor 2)	protein interactions	283248	28	2	19454	49	CTBP1,PRDM16
2.304e-03	-6.07	central nervous system myelination	biological process	GO:0022010	26	2	18204	50	GPM6B,ASPA
2.304e-03	-6.07	axon ensheathment in central nervous system	biological process	GO:0032291	26	2	18204	50	ASPA,GPM6B
2.304e-03	-6.07	C4-dicarboxylate transport	biological process	GO:0015740	26	2	18204	50	SLC1A2,SLC1A3
2.328e-03	-6.06	integrin-mediated signaling pathway	biological process	GO:0007229	96	3	18204	50	PTN,PLPP3,APOA1
2.366e-03	-6.05	amino acid transmembrane transporter activity	molecular function	GO:0015171	100	3	18094	48	SLC6A11,SLC1A2,SLC1A3
2.377e-03	-6.04	skeletal system development	biological process	GO:0001501	500	6	18204	50	NFIA,TRPS1,SOX5,FGFR3,FGFRL1,GJA1
2.394e-03	-6.03	DEP	smart domains	SM00049	21	2	9717	34	PREX1,PREX2
2.398e-03	-6.03	amino acid transmembrane transport	biological process	GO:0003333	97	3	18204	50	SLC6A11,SLC1A2,SLC1A3
2.410e-03	-6.03	pleura-mesothelioma	COSMIC cancer mutations	pleura-mesothelioma	4189	21	16828	47	FGFR3,PREX1,PRDM16,SOX5,SNTB1,GRK5,TRPS1,PREX2,GPM6B,DGKB,LRIG1,MSI2,QKI,PTPRZ1,BCAR3,LPIN2,AMOT,FARP1,USP6NL,RORA,FKBP5
2.415e-03	-6.03	USP30 (ubiquitin specific peptidase 30)	protein interactions	84749	106	3	19454	49	FGFR3,PRKN,QKI
2.415e-03	-6.03	PTN (pleiotrophin)	protein interactions	5764	106	3	19454	49	PTN,LAMA4,PTPRZ1
2.416e-03	-6.03	ALG6 (ALG6 alpha-1,3-glucosyltransferase)	protein interactions	29929	29	2	19454	49	PRKN,FGFR3
2.484e-03	-6.00	gastrulation with mouth forming second	biological process	GO:0001702	27	2	18204	50	PLPP3,AMOT
2.498e-03	-5.99	cellular response to organonitrogen compound	biological process	GO:0071417	505	6	18204	50	SLC1A3,GJA1,PRKN,SLC1A2,BCAR3,LPIN2
2.519e-03	-5.98	Apob (apolipoprotein B)	protein interactions	238055	1	1	19454	49	APOA1
2.519e-03	-5.98	Sh2b1 (SH2B adaptor protein 1)	protein interactions	20399	1	1	19454	49	FGFR3
2.519e-03	-5.98	GRXCR2 (glutaredoxin and cysteine rich domain containing 2)	protein interactions	643226	1	1	19454	49	PRKN
2.519e-03	-5.98	C1QL2 (complement C1q like 2)	protein interactions	165257	1	1	19454	49	ADGRB3
2.519e-03	-5.98	PCDHGA1 (protocadherin gamma subfamily A, 1)	protein interactions	56114	1	1	19454	49	PRKN
2.519e-03	-5.98	C1orf141 (chromosome 1 open reading frame 141)	protein interactions	400757	1	1	19454	49	PRKN
2.519e-03	-5.98	fgf3.L (fibroblast growth factor 3 L homeolog)	protein interactions	373669	1	1	19454	49	FGFR3
2.519e-03	-5.98	Atxn3 (ataxin 3)	protein interactions	60331	1	1	19454	49	PRKN
2.519e-03	-5.98	CFAP61 (cilia and flagella associated protein 61)	protein interactions	26074	1	1	19454	49	PRKN
2.519e-03	-5.98	IGHV3-15 (immunoglobulin heavy variable 3-15)	protein interactions	28448	1	1	19454	49	PRKN
2.519e-03	-5.98	FAM20A (FAM20A golgi associated secretory pathway pseudokinase)	protein interactions	54757	1	1	19454	49	PRKN
2.519e-03	-5.98	SNCA (synuclein alpha)	protein interactions	282857	1	1	19454	49	GRK5
2.519e-03	-5.98	ERVK-10 (endogenous retrovirus group K member 10)	protein interactions	100616101	1	1	19454	49	APOA1
2.519e-03	-5.98	FRMPD3 (FERM and PDZ domain containing 3)	protein interactions	84443	1	1	19454	49	PRKN
2.519e-03	-5.98	RFX8 (regulatory factor X8)	protein interactions	731220	1	1	19454	49	PRKN
2.519e-03	-5.98	MRO (maestro)	protein interactions	83876	1	1	19454	49	PRKN
2.519e-03	-5.98	Grik2 (glutamate ionotropic receptor kainate type subunit 2)	protein interactions	54257	1	1	19454	49	PRKN
2.519e-03	-5.98	IQCA1 (IQ motif containing with AAA domain 1)	protein interactions	79781	1	1	19454	49	PRKN
2.519e-03	-5.98	OR8G1 (olfactory receptor family 8 subfamily G member 1)	protein interactions	26494	1	1	19454	49	PRKN
2.519e-03	-5.98	LINC01553 (long intergenic non-protein coding RNA 1553)	protein interactions	283025	1	1	19454	49	PRKN
2.519e-03	-5.98	IZUMO3 (IZUMO family member 3)	protein interactions	100129669	1	1	19454	49	PRKN
2.519e-03	-5.98	Ube2l3 (ubiquitin-conjugating enzyme E2L 3)	protein interactions	363836	1	1	19454	49	PRKN
2.519e-03	-5.98	CALM1P1 (calmodulin 1 pseudogene 1)	protein interactions	802	1	1	19454	49	PRKN
2.519e-03	-5.98	Pals1 (protein associated with LIN7 1, MAGUK family member)	protein interactions	56217	1	1	19454	49	AMOT
2.519e-03	-5.98	E1A (E1A)	protein interactions	2958468	1	1	19454	49	CTBP1
2.519e-03	-5.98	FAM47C (family with sequence similarity 47 member C)	protein interactions	442444	1	1	19454	49	PRKN
2.519e-03	-5.98	AKR1E2 (aldo-keto reductase family 1 member E2)	protein interactions	83592	1	1	19454	49	PRKN
2.519e-03	-5.98	HDAC2 (histone deacetylase 2)	protein interactions	395635	1	1	19454	49	PRDM16
2.519e-03	-5.98	MSB4 (Rab GTPase-activating protein MSB4)	protein interactions	854037	1	1	19454	49	USP6NL
2.519e-03	-5.98	Patj (PATJ, crumbs cell polarity complex component)	protein interactions	12695	1	1	19454	49	AMOT
2.519e-03	-5.98	OR10A5 (olfactory receptor family 10 subfamily A member 5)	protein interactions	144124	1	1	19454	49	PRKN
2.521e-03	-5.98	B3GAT1 (beta-1,3-glucuronyltransferase 1)	protein interactions	27087	377	5	19454	49	FARP1,GJA1,ELOVL2,PLPP3,FGFRL1
2.536e-03	-5.98	MAP4K4 (mitogen-activated protein kinase kinase kinase kinase 4)	protein interactions	9448	227	4	19454	49	AMOT,GRK5,PRKN,GJA1
2.573e-03	-5.96	cell morphogenesis	biological process	GO:0000902	687	7	18204	50	PREX2,SLC1A3,PTN,SLC39A12,FARP1,NFIA,PTPRZ1
2.578e-03	-5.96	mouth	COSMIC cancer mutations	mouth	9004	35	16828	47	RORA,ZBTB20,PTN,UNC93A,NHSL1,NCKAP5,QKI,BCAR3,APOA1,FHOD3,PREX2,SLC1A2,ELOVL2,FGFR3,LAMA4,PRDM16,PREX1,USP6NL,SLC1A3,GPC5,TNS3,PTPRZ1,CTBP1,NPAS3,RFX4,SORCS2,LRIG1,DGKB,TRPS1,SNTB1,EGF,GRK5,SLC39A12,SLC4A4,SOX5
2.614e-03	-5.95	regulation of dendrite development	biological process	GO:0050773	100	3	18204	50	PTN,PREX1,ADGRB3
2.638e-03	-5.94	USP9X (ubiquitin specific peptidase 9 X-linked)	protein interactions	8239	381	5	19454	49	AMOT,GJA1,GRK5,PRKN,FGFR3
2.653e-03	-5.93	aspartoacylase activity	molecular function	GO:0019807	1	1	18094	48	ASPA
2.653e-03	-5.93	internal N(7)-methylguanine-containing RNA reader activity	molecular function	GO:0160089	1	1	18094	48	QKI
2.663e-03	-5.93	positive regulation of GTPase activity	biological process	GO:0043547	211	4	18204	50	PREX2,BCAR3,USP6NL,PREX1
2.700e-03	-5.91	RING-HC_RBR_parkin	interpro domains	IPR047535	1	1	18521	50	PRKN
2.700e-03	-5.91	Pro-epidermal_GF	interpro domains	IPR016317	1	1	18521	50	EGF
2.700e-03	-5.91	Quaking_NLS	interpro domains	IPR032367	1	1	18521	50	QKI
2.700e-03	-5.91	STAR_dimer	interpro domains	IPR032377	1	1	18521	50	QKI
2.700e-03	-5.91	C1_DGKbeta_rpt2	interpro domains	IPR047470	1	1	18521	50	DGKB
2.700e-03	-5.91	Na/ntran_symport_GABA_GAT3	interpro domains	IPR002982	1	1	18521	50	SLC6A11
2.700e-03	-5.91	Rcat_RBR_parkin	interpro domains	IPR047536	1	1	18521	50	PRKN
2.700e-03	-5.91	Rex2_DEP_1	interpro domains	IPR037367	1	1	18521	50	PREX2
2.700e-03	-5.91	Znf-RING_14	interpro domains	IPR041170	1	1	18521	50	PRKN
2.700e-03	-5.91	Connexin43_C	interpro domains	IPR013124	1	1	18521	50	GJA1
2.700e-03	-5.91	Parkin_Znf-RING	interpro domains	IPR041565	1	1	18521	50	PRKN
2.700e-03	-5.91	Alpha_helix_dom_sf	interpro domains	IPR035091	1	1	18521	50	GJA1
2.700e-03	-5.91	BRcat_RBR_parkin	interpro domains	IPR047534	1	1	18521	50	PRKN
2.700e-03	-5.91	Parkin	interpro domains	IPR003977	1	1	18521	50	PRKN
2.700e-03	-5.91	Connexin43	interpro domains	IPR002261	1	1	18521	50	GJA1
2.700e-03	-5.91	ELOVL2	interpro domains	IPR033680	1	1	18521	50	ELOVL2
2.700e-03	-5.91	TRPS1	interpro domains	IPR028440	1	1	18521	50	TRPS1
2.700e-03	-5.91	C1_DGKbeta-like_rpt1	interpro domains	IPR047471	1	1	18521	50	DGKB
2.700e-03	-5.91	PRDM16_PR-SET	interpro domains	IPR044410	1	1	18521	50	PRDM16
2.735e-03	-5.90	large_cell	COSMIC cancer mutations	large_cell	14845	47	16828	47	FGFR3,ELOVL2,PREX1,LAMA4,SLC1A2,FHOD3,APOA1,AQP4,QKI,NCKAP5,GJA1,UNC93A,NHSL1,FKBP5,ZBTB20,SLC4A4,FGFRL1,SOX5,SNTB1,TRPS1,GPM6B,DGKB,LRIG1,ASPA,SORCS2,NPAS3,AMOT,SLC6A11,PRDM16,PREX2,NFIA,BCAR3,FARP1,PTN,RORA,SLC39A12,EGF,GRK5,MSI2,CTBP1,PTPRZ1,LPIN2,RFX4,TNS3,GPC5,SLC1A3,USP6NL
2.742e-03	-5.90	kidney-carcinoma-renal_cell_carcinoma	COSMIC cancer mutations	kidney-carcinoma-renal_cell_carcinoma	4535	22	16828	47	GRK5,SNTB1,PREX1,PRDM16,SOX5,FGFR3,SLC39A12,DGKB,LRIG1,PREX2,GPM6B,TRPS1,BCAR3,LPIN2,AMOT,QKI,PTPRZ1,MSI2,FKBP5,RORA,USP6NL,FARP1
2.742e-03	-5.90	renal_cell_carcinoma	COSMIC cancer mutations	renal_cell_carcinoma	4535	22	16828	47	BCAR3,LPIN2,AMOT,QKI,PTPRZ1,MSI2,USP6NL,RORA,FKBP5,FARP1,GRK5,SNTB1,PREX1,PRDM16,SOX5,FGFR3,SLC39A12,DGKB,LRIG1,PREX2,GPM6B,TRPS1
2.743e-03	-5.90	CDC23 (cell division cycle 23)	protein interactions	8697	232	4	19454	49	FHOD3,PRKN,CTBP1,SOX5
2.747e-03	-5.90	negative regulation of spontaneous neurotransmitter secretion	biological process	GO:1904049	1	1	18204	50	PRKN
2.747e-03	-5.90	atrial ventricular junction remodeling	biological process	GO:0003294	1	1	18204	50	GJA1
2.747e-03	-5.90	milk ejection reflex	biological process	GO:0060156	1	1	18204	50	GJA1
2.758e-03	-5.89	C5orf34 (chromosome 5 open reading frame 34)	protein interactions	375444	31	2	19454	49	FKBP5,PRKN
2.764e-03	-5.89	Connexin43	gene3d domains	1.20.5.1130	1	1	14470	40	GJA1
2.764e-03	-5.89	-	gene3d domains	1.20.5.20	1	1	14470	40	APOA1
2.764e-03	-5.89	-	gene3d domains	1.20.5.4010	1	1	14470	40	QKI
2.764e-03	-5.89	-	gene3d domains	6.10.140.380	1	1	14470	40	APOA1
2.764e-03	-5.89	-	gene3d domains	6.10.250.1740	1	1	14470	40	FGFR3
2.810e-03	-5.87	Quaking_NLS	pfam domains	PF16551	1	1	17795	50	QKI
2.810e-03	-5.87	zf-RING_12	pfam domains	PF17976	1	1	17795	50	PRKN
2.810e-03	-5.87	zf-RING_14	pfam domains	PF17978	1	1	17795	50	PRKN
2.810e-03	-5.87	FGFR3_TM	pfam domains	PF21165	1	1	17795	50	FGFR3
2.810e-03	-5.87	Connexin43	pfam domains	PF03508	1	1	17795	50	GJA1
2.810e-03	-5.87	STAR_dimer	pfam domains	PF16544	1	1	17795	50	QKI
2.820e-03	-5.87	t(4;14) translocations of FGFR3	REACTOME pathways	R-HSA-2033515	1	1	10285	29	FGFR3
2.820e-03	-5.87	Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane	REACTOME pathways	R-HSA-190840	1	1	10285	29	GJA1
2.823e-03	-5.87	TBR1 (T-box brain transcription factor 1)	protein interactions	10716	112	3	19454	49	TRPS1,NFIA,SOX5
2.843e-03	-5.86	regulation of neural precursor cell proliferation	biological process	GO:2000177	103	3	18204	50	EGF,PTPRZ1,PTN
2.843e-03	-5.86	regulation of biomineral tissue development	biological process	GO:0070167	103	3	18204	50	PTN,GPM6B,GJA1
2.866e-03	-5.85	beta-catenin binding	molecular function	GO:0008013	107	3	18094	48	RORA,GJA1,PRKN
2.906e-03	-5.84	ARF6 (ADP ribosylation factor 6)	protein interactions	382	568	6	19454	49	SLC1A3,GJA1,FARP1,ELOVL2,USP6NL,PLPP3
2.937e-03	-5.83	C1orf21 (chromosome 1 open reading frame 21)	protein interactions	81563	32	2	19454	49	PRKN,GJA1
2.940e-03	-5.83	astrocytoma_Grade_III	COSMIC cancer mutations	astrocytoma_Grade_III	1544	11	16828	47	TNS3,GPC5,FARP1,NCKAP5,BCAR3,FHOD3,SLC39A12,FGFR3,PRDM16,SNTB1,GRK5
2.958e-03	-5.82	lung-carcinoma	COSMIC cancer mutations	lung-carcinoma	4255	21	16828	47	TRPS1,GPM6B,PREX2,LRIG1,DGKB,FGFR3,SOX5,PRDM16,PREX1,SNTB1,GRK5,FARP1,RORA,USP6NL,FKBP5,MSI2,PTPRZ1,QKI,LPIN2,AMOT,BCAR3
3.042e-03	-5.80	non_small_cell_carcinoma	COSMIC cancer mutations	non_small_cell_carcinoma	5198	24	16828	47	USP6NL,SLC1A3,PTPRZ1,NPAS3,LPIN2,AMOT,MSI2,LRIG1,DGKB,TRPS1,GPM6B,SNTB1,GRK5,SOX5,FARP1,FKBP5,RORA,QKI,BCAR3,FHOD3,PREX2,FGFR3,PRDM16,PREX1
3.042e-03	-5.80	lung-carcinoma-non_small_cell_carcinoma	COSMIC cancer mutations	lung-carcinoma-non_small_cell_carcinoma	5198	24	16828	47	TRPS1,GPM6B,LRIG1,DGKB,SOX5,SNTB1,GRK5,USP6NL,SLC1A3,MSI2,PTPRZ1,NPAS3,AMOT,LPIN2,FHOD3,PREX2,FGFR3,PRDM16,PREX1,FARP1,RORA,FKBP5,QKI,BCAR3
3.062e-03	-5.79	L-glutamate import	biological process	GO:0051938	30	2	18204	50	SLC1A3,SLC1A2
3.087e-03	-5.78	oesophagus-carcinoma	COSMIC cancer mutations	oesophagus-carcinoma	4269	21	16828	47	SORCS2,RFX4,PTPRZ1,NCKAP5,NHSL1,UNC93A,PTN,USP6NL,ZBTB20,PRDM16,PREX1,SOX5,SLC39A12,FGFR3,SLC4A4,ELOVL2,PREX2,NFIA,FHOD3,TRPS1,LRIG1
3.115e-03	-5.77	MAPK3 (mitogen-activated protein kinase 3)	protein interactions	5595	396	5	19454	49	PRKN,TRPS1,GJA1,AMOT,FKBP5
3.122e-03	-5.77	SNCAIP (synuclein alpha interacting protein)	protein interactions	9627	33	2	19454	49	PTN,PRKN
3.136e-03	-5.76	central_nervous_system-cerebellum-glioma-astrocytoma_Grade_I	COSMIC cancer mutations	central_nervous_system-cerebellum-glioma-astrocytoma_Grade_I	105	3	16828	47	QKI,GPC5,PRDM16
3.160e-03	-5.76	skin-malignant_melanoma-acral_lentiginous	COSMIC cancer mutations	skin-malignant_melanoma-acral_lentiginous	30	2	16828	47	PREX2,FGFR3
3.160e-03	-5.76	lentigo_maligna	COSMIC cancer mutations	lentigo_maligna	30	2	16828	47	FGFR3,PREX2
3.174e-03	-5.75	blood vessel development	biological process	GO:0001568	530	6	18204	50	GJA1,RORA,AMOT,PLPP3,QKI,EGF
3.194e-03	-5.75	CHORDC1 (cysteine and histidine rich domain containing 1)	protein interactions	26973	117	3	19454	49	FKBP5,AMOT,PRKN
3.202e-03	-5.74	skin-head_neck-carcinoma-squamous_cell_carcinoma	COSMIC cancer mutations	skin-head_neck-carcinoma-squamous_cell_carcinoma	14191	46	16828	47	NFIA,PREX2,PRDM16,FARP1,RORA,PTN,BCAR3,EGF,GRK5,SLC39A12,USP6NL,SLC1A3,GPC5,TNS3,PTPRZ1,CTBP1,LPIN2,RFX4,APOA1,FHOD3,SLC1A2,ELOVL2,FGFR3,LAMA4,PREX1,ZBTB20,FKBP5,UNC93A,NHSL1,NCKAP5,QKI,GJA1,AQP4,LRIG1,DGKB,TRPS1,GPM6B,SNTB1,SLC4A4,FGFRL1,SOX5,SLC6A11,NPAS3,AMOT,ASPA,SORCS2
3.238e-03	-5.73	functioning	COSMIC cancer mutations	functioning	1803	12	16828	47	PTPRZ1,NCKAP5,LPIN2,RFX4,SLC6A11,TNS3,NHSL1,FARP1,ZBTB20,SOX5,GRK5,SLC1A2
3.238e-03	-5.73	adrenal_gland-adrenal_gland-adrenal_cortical_carcinoma-functioning	COSMIC cancer mutations	adrenal_gland-adrenal_gland-adrenal_cortical_carcinoma-functioning	1803	12	16828	47	FARP1,ZBTB20,SLC6A11,NHSL1,TNS3,NCKAP5,PTPRZ1,RFX4,LPIN2,GRK5,SLC1A2,SOX5
3.249e-03	-5.73	bicarbonate transmembrane transporter activity	molecular function	GO:0015106	32	2	18094	48	SLC4A4,SLC39A12
3.286e-03	-5.72	Transport of inorganic cations/anions and amino acids/oligopeptides	REACTOME pathways	R-HSA-425393	107	3	10285	29	SLC1A3,SLC4A4,SLC1A2
3.312e-03	-5.71	PTPRZ1 (protein tyrosine phosphatase receptor type Z1)	protein interactions	5803	34	2	19454	49	PTN,PTPRZ1
3.335e-03	-5.70	TAB1 (TGF-beta activated kinase 1 (MAP3K7) binding protein 1)	protein interactions	10454	245	4	19454	49	FARP1,GRK5,PRKN,FKBP5
3.350e-03	-5.70	ANKRD26 (ankyrin repeat domain containing 26)	protein interactions	22852	119	3	19454	49	GJA1,AMOT,NCKAP5
3.350e-03	-5.70	TTC4 (tetratricopeptide repeat domain 4)	protein interactions	7268	119	3	19454	49	FGFR3,PRKN,FKBP5
3.372e-03	-5.69	RAC1 (Rac family small GTPase 1)	protein interactions	5879	1005	8	19454	49	TNS3,USP6NL,FARP1,PREX1,GJA1,PREX2,PRKN,SLC1A3
3.393e-03	-5.69	MET promotes cell motility	REACTOME pathways	R-HSA-8875878	31	2	10285	29	LAMA4,TNS3
3.444e-03	-5.67	GAT3TRNSPORT	prints domains	PR01197	1	1	5227	18	SLC6A11
3.444e-03	-5.67	CONNEXINA1	prints domains	PR01132	1	1	5227	18	GJA1
3.444e-03	-5.67	AQUAPORIN4	prints domains	PR02016	1	1	5227	18	AQP4
3.444e-03	-5.67	PARKIN	prints domains	PR01475	1	1	5227	18	PRKN
3.479e-03	-5.66	transepithelial transport	biological process	GO:0070633	32	2	18204	50	SLC1A2,SLC1A3
3.479e-03	-5.66	positive regulation of ATP metabolic process	biological process	GO:1903580	32	2	18204	50	SLC4A4,ZBTB20
3.484e-03	-5.66	MET (MET proto-oncogene, receptor tyrosine kinase)	protein interactions	4233	248	4	19454	49	TNS3,LRIG1,BCAR3,GJA1
3.498e-03	-5.66	cell population proliferation	biological process	GO:0008283	726	7	18204	50	SOX5,RORA,GJA1,APOA1,NFIA,FGFR3,EGF
3.574e-03	-5.63	kidney-carcinoma	COSMIC cancer mutations	kidney-carcinoma	3720	19	16828	47	USP6NL,RORA,FKBP5,FARP1,MSI2,BCAR3,LPIN2,QKI,PTPRZ1,PREX2,TRPS1,DGKB,LRIG1,PRDM16,PREX1,SOX5,FGFR3,GRK5,SNTB1
3.593e-03	-5.63	AVPR2 (arginine vasopressin receptor 2)	protein interactions	554	122	3	19454	49	GJA1,ELOVL2,GRK5
3.632e-03	-5.62	aggresome	cellular component	GO:0016235	35	2	19108	49	PRDM16,PRKN
3.652e-03	-5.61	circulatory system development	biological process	GO:0072359	933	8	18204	50	GJA1,AMOT,RORA,FHOD3,QKI,EGF,PLPP3,FGFRL1
3.676e-03	-5.61	RIOK2 (RIO kinase 2)	protein interactions	55781	123	3	19454	49	BCAR3,PRDM16,PRKN
3.692e-03	-5.60	dendrite development	biological process	GO:0016358	113	3	18204	50	FARP1,PTN,PREX2
3.697e-03	-5.60	blood vessel endothelial cell migration	biological process	GO:0043534	33	2	18204	50	APOA1,AMOT
3.697e-03	-5.60	response to auditory stimulus	biological process	GO:0010996	33	2	18204	50	SLC1A3,PTN
3.740e-03	-5.59	PRKAA1 (protein kinase AMP-activated catalytic subunit alpha 1)	protein interactions	5562	253	4	19454	49	SLC4A4,PRKN,CTBP1,FKBP5
3.741e-03	-5.59	Glycerophospholipid metabolism	KEGG pathways	ko00564	95	3	7161	24	DGKB,PLPP3,LPIN2
3.741e-03	-5.59	Glycerophospholipid metabolism	KEGG pathways	hsa00564	95	3	7161	24	PLPP3,LPIN2,DGKB
3.807e-03	-5.57	vasculature development	biological process	GO:0001944	550	6	18204	50	AMOT,GJA1,RORA,QKI,EGF,PLPP3
3.846e-03	-5.56	TCHP (trichoplein keratin filament binding)	protein interactions	84260	125	3	19454	49	PRDM16,PRKN,AMOT
3.846e-03	-5.56	STXBP1 (syntaxin binding protein 1)	protein interactions	6812	125	3	19454	49	GJA1,PREX1,PRKN
3.847e-03	-5.56	DYNLL2 (dynein light chain LC8-type 2)	protein interactions	140735	255	4	19454	49	TRPS1,NFIA,NHSL1,AMOT
3.901e-03	-5.55	IARS2 (isoleucyl-tRNA synthetase 2, mitochondrial)	protein interactions	55699	256	4	19454	49	GJA1,FGFR3,PRKN,FKBP5
3.913e-03	-5.54	MOCOS (molybdenum cofactor sulfurase)	protein interactions	55034	37	2	19454	49	PRKN,APOA1
3.913e-03	-5.54	DGAT1 (diacylglycerol O-acyltransferase 1)	protein interactions	8694	37	2	19454	49	APOA1,PRKN
3.913e-03	-5.54	TRNAU1AP (tRNA selenocysteine 1 associated protein 1)	protein interactions	54952	37	2	19454	49	ZBTB20,QKI
3.953e-03	-5.53	central_nervous_system-brainstem-glioma-oligoastrocytoma_Grade_III	COSMIC cancer mutations	central_nervous_system-brainstem-glioma-oligoastrocytoma_Grade_III	114	3	16828	47	SLC1A2,SOX5,PREX2
4.021e-03	-5.52	PAX9 (paired box 9)	protein interactions	5083	127	3	19454	49	QKI,NFIA,TRPS1
4.046e-03	-5.51	central_nervous_system-parietal_lobe-glioma-astrocytoma_Grade_I	COSMIC cancer mutations	central_nervous_system-parietal_lobe-glioma-astrocytoma_Grade_I	34	2	16828	47	FGFR3,QKI
4.052e-03	-5.51	glial cell projection	cellular component	GO:0097386	37	2	19108	49	SLC1A2,AQP4
4.111e-03	-5.49	ATG5 (autophagy related 5)	protein interactions	9474	128	3	19454	49	FGFR3,PRKN,GJA1
4.123e-03	-5.49	STK33 (serine/threonine kinase 33)	protein interactions	65975	38	2	19454	49	PRKN,FKBP5
4.201e-03	-5.47	CHD7 (chromodomain helicase DNA binding protein 7)	protein interactions	55636	129	3	19454	49	SOX5,FKBP5,ZBTB20
4.202e-03	-5.47	Choline metabolism in cancer	KEGG pathways	ko05231	99	3	7161	24	EGF,DGKB,PLPP3
4.202e-03	-5.47	Choline metabolism in cancer	KEGG pathways	hsa05231	99	3	7161	24	DGKB,EGF,PLPP3
4.339e-03	-5.44	PDK2 (pyruvate dehydrogenase kinase 2)	protein interactions	5164	39	2	19454	49	FKBP5,PRKN
4.339e-03	-5.44	CHPF (chondroitin polymerizing factor)	protein interactions	79586	39	2	19454	49	PRKN,SLC39A12
4.386e-03	-5.43	TRPS1 (transcriptional repressor GATA binding 1)	protein interactions	7227	131	3	19454	49	CTBP1,SOX5,NFIA
4.480e-03	-5.41	DCAF11 (DDB1 and CUL4 associated factor 11)	protein interactions	80344	132	3	19454	49	CTBP1,PRKN,LPIN2
4.488e-03	-5.41	extremity	COSMIC cancer mutations	extremity	1876	12	16828	47	USP6NL,FKBP5,APOA1,PREX2,SLC6A11,FHOD3,BCAR3,PTPRZ1,CTBP1,PRDM16,SORCS2,FGFR3
4.528e-03	-5.40	central_nervous_system-thalamus-glioma-astrocytoma_Grade_I	COSMIC cancer mutations	central_nervous_system-thalamus-glioma-astrocytoma_Grade_I	36	2	16828	47	QKI,FGFR3
4.555e-03	-5.39	prostate-adenoma	COSMIC cancer mutations	prostate-adenoma	1634	11	16828	47	NPAS3,EGF,PTPRZ1,PREX1,SOX5,FARP1,PTN,ZBTB20,FHOD3,SLC6A11,GPC5
4.561e-03	-5.39	GJC1 (gap junction protein gamma 1)	protein interactions	10052	40	2	19454	49	GJA1,SLC39A12
4.561e-03	-5.39	CHGB (chromogranin B)	protein interactions	1114	40	2	19454	49	PRKN,FGFR3
4.575e-03	-5.39	DUT (deoxyuridine triphosphatase)	protein interactions	1854	133	3	19454	49	PRKN,FKBP5,CTBP1
4.588e-03	-5.38	MCM6 (minichromosome maintenance complex component 6)	protein interactions	4175	268	4	19454	49	PRDM16,TRPS1,PRKN,FKBP5
4.605e-03	-5.38	positive regulation of neurogenesis	biological process	GO:0050769	246	4	18204	50	QKI,ASPA,PTN,PTPRZ1
4.628e-03	-5.38	focal adhesion	cellular component	GO:0005925	427	5	19108	49	SNTB1,TNS3,GJA1,BCAR3,FGFR3
4.631e-03	-5.38	positive regulation of nucleotide metabolic process	biological process	GO:0045981	37	2	18204	50	ZBTB20,SLC4A4
4.631e-03	-5.38	positive regulation of purine nucleotide metabolic process	biological process	GO:1900544	37	2	18204	50	SLC4A4,ZBTB20
4.631e-03	-5.38	bicarbonate transport	biological process	GO:0015701	37	2	18204	50	SLC39A12,SLC4A4
4.631e-03	-5.38	positive regulation of morphogenesis of an epithelium	biological process	GO:1905332	37	2	18204	50	EGF,GJA1
4.649e-03	-5.37	RND3 (Rho family GTPase 3)	protein interactions	390	269	4	19454	49	USP6NL,CTBP1,SNTB1,FARP1
4.649e-03	-5.37	SRPRA (SRP receptor subunit alpha)	protein interactions	6734	269	4	19454	49	PRKN,FGFR3,GJA1,SLC39A12
4.692e-03	-5.36	hand	COSMIC cancer mutations	hand	566	6	16828	47	AMOT,FARP1,PREX2,PREX1,FGFR3,SLC4A4
4.705e-03	-5.36	positive regulation of molecular function	biological process	GO:0044093	1192	9	18204	50	USP6NL,APOA1,PREX1,PRKN,PREX2,FGFR3,PLPP3,EGF,BCAR3
4.710e-03	-5.36	WDR6 (WD repeat domain 6)	protein interactions	11180	270	4	19454	49	GJA1,FARP1,PRKN,FKBP5
4.770e-03	-5.35	CEP350 (centrosomal protein 350)	protein interactions	9857	135	3	19454	49	PRKN,AMOT,NCKAP5
4.777e-03	-5.34	ZFPL1 (zinc finger protein like 1)	protein interactions	7542	438	5	19454	49	PRKN,GJA1,FARP1,SLC39A12,USP6NL
4.778e-03	-5.34	central_nervous_system-third_ventricle-glioma-astrocytoma_Grade_I	COSMIC cancer mutations	central_nervous_system-third_ventricle-glioma-astrocytoma_Grade_I	37	2	16828	47	QKI,FGFR3
4.788e-03	-5.34	regulation of ossification	biological process	GO:0030278	124	3	18204	50	PTN,GPM6B,GJA1
4.788e-03	-5.34	fat cell differentiation	biological process	GO:0045444	124	3	18204	50	GRK5,PRDM16,CTBP1
4.808e-03	-5.34	bone-Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour	COSMIC cancer mutations	bone-Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour	6023	26	16828	47	EGF,SLC4A4,SLC39A12,SOX5,FGFRL1,LRIG1,GPM6B,PTPRZ1,NPAS3,LPIN2,ASPA,SORCS2,SLC1A3,SLC6A11,TNS3,FGFR3,LAMA4,PRDM16,PREX1,FHOD3,PREX2,NCKAP5,FARP1,RORA,ZBTB20,UNC93A
4.834e-03	-5.33	enzyme activator activity	molecular function	GO:0008047	599	6	18094	48	APOA1,PREX1,USP6NL,PREX2,ADGRB3,EGF
4.869e-03	-5.32	SNX9 (sorting nexin 9)	protein interactions	51429	136	3	19454	49	CTBP1,SLC1A3,PRKN
4.880e-03	-5.32	amino acid import across plasma membrane	biological process	GO:0089718	38	2	18204	50	SLC1A3,SLC1A2
4.880e-03	-5.32	positive regulation of DNA binding	biological process	GO:0043388	38	2	18204	50	EGF,PRKN
4.915e-03	-5.32	soft_tissue-striated_muscle-rhabdomyosarcoma-alveolar	COSMIC cancer mutations	soft_tissue-striated_muscle-rhabdomyosarcoma-alveolar	2414	14	16828	47	GRK5,FGFRL1,FGFR3,PREX2,NFIA,FHOD3,TRPS1,CTBP1,NPAS3,NCKAP5,SORCS2,SLC1A3,USP6NL,NHSL1
4.915e-03	-5.32	alveolar	COSMIC cancer mutations	alveolar	2414	14	16828	47	GRK5,FGFR3,FGFRL1,FHOD3,TRPS1,PREX2,NFIA,NPAS3,CTBP1,NCKAP5,SORCS2,SLC1A3,USP6NL,NHSL1
4.916e-03	-5.32	RHOQ (ras homolog family member Q)	protein interactions	23433	441	5	19454	49	TNS3,USP6NL,FARP1,GJA1,SNTB1
4.928e-03	-5.31	cellular response to nitrogen compound	biological process	GO:1901699	580	6	18204	50	SLC1A3,GJA1,PRKN,SLC1A2,BCAR3,LPIN2
4.951e-03	-5.31	heat shock protein binding	molecular function	GO:0031072	130	3	18094	48	APOA1,PRKN,FKBP5
4.969e-03	-5.30	TBL1X (transducin beta like 1 X-linked)	protein interactions	6907	137	3	19454	49	NFIA,SOX5,CTBP1
5.000e-03	-5.30	skin-ear-malignant_melanoma	COSMIC cancer mutations	skin-ear-malignant_melanoma	124	3	16828	47	GRK5,FGFRL1,SLC6A11
5.018e-03	-5.29	FGF1 (fibroblast growth factor 1)	protein interactions	2246	42	2	19454	49	FGFR3,FARP1
5.031e-03	-5.29	Fkbp3 (FK506 binding protein 3)	protein interactions	30795	2	1	19454	49	CTBP1
5.031e-03	-5.29	NT5DC4 (5'-nucleotidase domain containing 4)	protein interactions	284958	2	1	19454	49	PRKN
5.031e-03	-5.29	SLC9B2 (solute carrier family 9 member B2)	protein interactions	133308	2	1	19454	49	PRKN
5.031e-03	-5.29	CCNYL2 (cyclin Y like 2 (pseudogene))	protein interactions	414194	2	1	19454	49	PRKN
5.031e-03	-5.29	THSD1 (thrombospondin type 1 domain containing 1)	protein interactions	55901	2	1	19454	49	GJA1
5.031e-03	-5.29	LRGUK (leucine rich repeats and guanylate kinase domain containing)	protein interactions	136332	2	1	19454	49	PRKN
5.031e-03	-5.29	ZFP92 (ZFP92 zinc finger protein)	protein interactions	139735	2	1	19454	49	PRKN
5.031e-03	-5.29	MSB3 (Rab GTPase-activating protein MSB3)	protein interactions	855423	2	1	19454	49	USP6NL
5.031e-03	-5.29	SLC24A4 (solute carrier family 24 member 4)	protein interactions	123041	2	1	19454	49	PRKN
5.031e-03	-5.29	CACNA1B (calcium voltage-gated channel subunit alpha1 B)	protein interactions	100008979	2	1	19454	49	PRKN
5.031e-03	-5.29	BTBD17 (BTB domain containing 17)	protein interactions	388419	2	1	19454	49	PRDM16
5.031e-03	-5.29	EYS (eyes shut homolog)	protein interactions	346007	2	1	19454	49	PRKN
5.031e-03	-5.29	HERC2P3 (HERC2 pseudogene 3)	protein interactions	283755	2	1	19454	49	PRKN
5.031e-03	-5.29	BHLHE22 (basic helix-loop-helix family member e22)	protein interactions	27319	2	1	19454	49	PRKN
5.031e-03	-5.29	Septin5 (septin 5)	protein interactions	18951	2	1	19454	49	PRKN
5.031e-03	-5.29	CSRNP3 (cysteine and serine rich nuclear protein 3)	protein interactions	80034	2	1	19454	49	PRKN
5.031e-03	-5.29	DEFB126 (defensin beta 126)	protein interactions	81623	2	1	19454	49	GJA1
5.031e-03	-5.29	TTC34 (tetratricopeptide repeat domain 34)	protein interactions	100287898	2	1	19454	49	PRKN
5.031e-03	-5.29	EVPLL (envoplakin like)	protein interactions	645027	2	1	19454	49	PRKN
5.031e-03	-5.29	SIDT1 (SID1 transmembrane family member 1)	protein interactions	54847	2	1	19454	49	PRKN
5.035e-03	-5.29	central_nervous_system-brainstem-glioma-astrocytoma_Grade_I	COSMIC cancer mutations	central_nervous_system-brainstem-glioma-astrocytoma_Grade_I	38	2	16828	47	QKI,FGFR3
5.070e-03	-5.28	APOB (apolipoprotein B)	protein interactions	338	138	3	19454	49	PRKN,APOA1,GJA1
5.100e-03	-5.28	cell-substrate junction	cellular component	GO:0030055	437	5	19108	49	FGFR3,BCAR3,GJA1,TNS3,SNTB1
5.134e-03	-5.27	cellular response to alkaloid	biological process	GO:0071312	39	2	18204	50	SLC1A2,SLC1A3
5.167e-03	-5.27	cerebellum	COSMIC cancer mutations	cerebellum	769	7	16828	47	FHOD3,GPC5,PRDM16,SORCS2,QKI,NPAS3,PTPRZ1
5.231e-03	-5.25	nasopharyngeal_carcinoma	COSMIC cancer mutations	nasopharyngeal_carcinoma	1425	10	16828	47	NFIA,NHSL1,PREX2,NCKAP5,QKI,RFX4,SLC1A2,FGFR3,SLC4A4,FGFRL1
5.231e-03	-5.25	upper_aerodigestive_tract-pharynx-carcinoma-nasopharyngeal_carcinoma	COSMIC cancer mutations	upper_aerodigestive_tract-pharynx-carcinoma-nasopharyngeal_carcinoma	1425	10	16828	47	NHSL1,NFIA,PREX2,NCKAP5,QKI,SLC1A2,RFX4,SLC4A4,FGFR3,FGFRL1
5.231e-03	-5.25	myelination	biological process	GO:0042552	128	3	18204	50	ASPA,GPM6B,QKI
5.234e-03	-5.25	Fatty acid, triacylglycerol, and ketone body metabolism	REACTOME pathways	R-HSA-535734	253	4	10285	29	LPIN2,ELOVL2,APOA1,RORA
5.254e-03	-5.25	FGF4 (fibroblast growth factor 4)	protein interactions	2249	43	2	19454	49	FGFR3,FARP1
5.254e-03	-5.25	GPRIN3 (GPRIN family member 3)	protein interactions	285513	43	2	19454	49	GJA1,PRKN
5.254e-03	-5.25	PDCD2 (programmed cell death 2)	protein interactions	5134	43	2	19454	49	FKBP5,PRKN
5.254e-03	-5.25	SDC3 (syndecan 3)	protein interactions	9672	43	2	19454	49	FARP1,PTN
5.353e-03	-5.23	TSG101 (tumor susceptibility 101)	protein interactions	7251	280	4	19454	49	QKI,GJA1,PRKN,PRDM16
5.359e-03	-5.23	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-follicular_lymphoma	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-follicular_lymphoma	981	8	16828	47	DGKB,RORA,FHOD3,GPC5,NCKAP5,SORCS2,PRDM16,SOX5
5.377e-03	-5.23	skin-hand-carcinoma-squamous_cell_carcinoma	COSMIC cancer mutations	skin-hand-carcinoma-squamous_cell_carcinoma	407	5	16828	47	SLC4A4,FGFR3,PREX1,FARP1,AMOT
5.382e-03	-5.22	MAEA (macrophage erythroblast attacher, E3 ubiquitin ligase)	protein interactions	10296	141	3	19454	49	NCKAP5,GRK5,PRKN
5.382e-03	-5.22	LLGL1 (LLGL scribble cell polarity complex component 1)	protein interactions	3996	141	3	19454	49	FKBP5,GJA1,PRKN
5.382e-03	-5.22	AP3M1 (adaptor related protein complex 3 subunit mu 1)	protein interactions	26985	141	3	19454	49	AQP4,PRKN,GRK5
5.382e-03	-5.22	NUDCD3 (NudC domain containing 3)	protein interactions	23386	141	3	19454	49	PRKN,FGFR3,FKBP5
5.386e-03	-5.22	membrane	cellular component	GO:0016020	9220	33	19108	49	UNC93A,LRIG1,GRK5,SLC4A4,PREX2,GPC5,FKBP5,FGFRL1,PREX1,EGF,SLC39A12,ELOVL2,SORCS2,PTN,FGFR3,APOA1,PLPP3,LPIN2,BCAR3,GJA1,AQP4,AMOT,FARP1,SLC1A2,SLC6A11,USP6NL,ADGRB3,SNTB1,PRKN,SLC1A3,PTPRZ1,DGKB,GPM6B
5.392e-03	-5.22	PTN_MK_heparin-bd_GF_CS	interpro domains	IPR020092	2	1	18521	50	PTN
5.392e-03	-5.22	PTN/MK_diS_sf	interpro domains	IPR020091	2	1	18521	50	PTN
5.392e-03	-5.22	MSI_RRM2	interpro domains	IPR034126	2	1	18521	50	MSI2
5.392e-03	-5.22	Aste_AspA	interpro domains	IPR007036	2	1	18521	50	ASPA
5.392e-03	-5.22	Aspartoacylase	interpro domains	IPR016708	2	1	18521	50	ASPA
5.392e-03	-5.22	Midkine_heparin-bd_GF	interpro domains	IPR000762	2	1	18521	50	PTN
5.392e-03	-5.22	ZIP4_N	interpro domains	IPR041137	2	1	18521	50	SLC39A12
5.392e-03	-5.22	NCKAP5_C	interpro domains	IPR032769	2	1	18521	50	NCKAP5
5.392e-03	-5.22	Ion_channel_UNC-93	interpro domains	IPR010291	2	1	18521	50	UNC93A
5.392e-03	-5.22	ZIP4_12_EF-hand	interpro domains	IPR049406	2	1	18521	50	SLC39A12
5.392e-03	-5.22	CtBP	interpro domains	IPR043322	2	1	18521	50	CTBP1
5.392e-03	-5.22	PTN/MK_N_dom_sf	interpro domains	IPR037122	2	1	18521	50	PTN
5.392e-03	-5.22	Alpha_CARP_receptor-type	interpro domains	IPR041887	2	1	18521	50	PTPRZ1
5.392e-03	-5.22	PTN/MK_C_dom	interpro domains	IPR020090	2	1	18521	50	PTN
5.392e-03	-5.22	PTN/MK_C_dom_sf	interpro domains	IPR038130	2	1	18521	50	PTN
5.392e-03	-5.22	FHOD1_GBD_N	interpro domains	IPR041387	2	1	18521	50	FHOD3
5.392e-03	-5.22	Nckap5l	interpro domains	IPR026163	2	1	18521	50	NCKAP5
5.392e-03	-5.22	PTN/MK_N_dom	interpro domains	IPR020089	2	1	18521	50	PTN
5.432e-03	-5.22	Ig_I-set	interpro domains	IPR013098	132	3	18521	50	LRIG1,FGFR3,FGFRL1
5.461e-03	-5.21	axon ensheathment	biological process	GO:0008366	130	3	18204	50	ASPA,GPM6B,QKI
5.461e-03	-5.21	ensheathment of neurons	biological process	GO:0007272	130	3	18204	50	QKI,ASPA,GPM6B
5.486e-03	-5.21	regulation of protein linear polyubiquitination	biological process	GO:1902528	2	1	18204	50	PRKN
5.486e-03	-5.21	fibroblast growth factor receptor apoptotic signaling pathway	biological process	GO:1902178	2	1	18204	50	FGFR3
5.486e-03	-5.21	negative regulation of primary amine oxidase activity	biological process	GO:1902283	2	1	18204	50	PRKN
5.486e-03	-5.21	negative regulation of endosome organization	biological process	GO:1904979	2	1	18204	50	PRKN
5.486e-03	-5.21	positive regulation of protein linear polyubiquitination	biological process	GO:1902530	2	1	18204	50	PRKN
5.486e-03	-5.21	positive regulation of retrograde transport, endosome to Golgi	biological process	GO:1905281	2	1	18204	50	PRKN
5.486e-03	-5.21	dendrite regeneration	biological process	GO:0031104	2	1	18204	50	PTN
5.486e-03	-5.21	negative regulation of 3'-UTR-mediated mRNA stabilization	biological process	GO:1905869	2	1	18204	50	QKI
5.486e-03	-5.21	regulation of intralumenal vesicle formation	biological process	GO:1905365	2	1	18204	50	PRKN
5.486e-03	-5.21	negative regulation of endoplasmic reticulum stress-induced neuron intrinsic apoptotic signaling pathway	biological process	GO:1903382	2	1	18204	50	PRKN
5.486e-03	-5.21	retrograde trans-synaptic signaling by trans-synaptic protein complex	biological process	GO:0098942	2	1	18204	50	FARP1
5.486e-03	-5.21	regulation protein catabolic process at presynapse	biological process	GO:0140251	2	1	18204	50	PRKN
5.486e-03	-5.21	retrograde transport, plasma membrane to Golgi	biological process	GO:0035526	2	1	18204	50	USP6NL
5.486e-03	-5.21	negative regulation of intralumenal vesicle formation	biological process	GO:1905366	2	1	18204	50	PRKN
5.486e-03	-5.21	myofibroblast contraction	biological process	GO:1990764	2	1	18204	50	QKI
5.486e-03	-5.21	regulation of sphingolipid mediated signaling pathway	biological process	GO:1902068	2	1	18204	50	PLPP3
5.486e-03	-5.21	regulation of spontaneous neurotransmitter secretion	biological process	GO:1904048	2	1	18204	50	PRKN
5.489e-03	-5.21	SDC2 (syndecan 2)	protein interactions	6383	142	3	19454	49	FGFRL1,FARP1,FGFR3
5.489e-03	-5.21	GIT1 (GIT ArfGAP 1)	protein interactions	28964	142	3	19454	49	GRK5,PRKN,PTPRZ1
5.496e-03	-5.20	OGFR (opioid growth factor receptor)	protein interactions	11054	44	2	19454	49	FKBP5,PRKN
5.496e-03	-5.20	PGK2 (phosphoglycerate kinase 2)	protein interactions	5232	44	2	19454	49	PRKN,ASPA
5.496e-03	-5.20	FER (FER tyrosine kinase)	protein interactions	2241	44	2	19454	49	PRKN,FKBP5
5.505e-03	-5.20	Sudden Infant Death Syndrome (SIDS) Susceptibility Pathways	WikiPathways	WP706	162	4	5310	24	GJA1,AQP4,RORA,SLC1A3
5.521e-03	-5.20	Pleiotrophin/Midkine, N-terminal domain	gene3d domains	2.20.60.10	2	1	14470	40	PTN
5.521e-03	-5.20	-	gene3d domains	6.10.250.2260	2	1	14470	40	GRK5
5.521e-03	-5.20	-	gene3d domains	2.20.25.160	2	1	14470	40	ASPA
5.545e-03	-5.19	neutral L-amino acid transmembrane transporter activity	molecular function	GO:0015175	42	2	18094	48	SLC1A2,SLC1A3
5.566e-03	-5.19	lower_back	COSMIC cancer mutations	lower_back	40	2	16828	47	SLC6A11,FGFR3
5.612e-03	-5.18	PTN_MK_C	pfam domains	PF01091	2	1	17795	50	PTN
5.612e-03	-5.18	NCKAP5	pfam domains	PF15246	2	1	17795	50	NCKAP5
5.612e-03	-5.18	UNC-93	pfam domains	PF05978	2	1	17795	50	UNC93A
5.612e-03	-5.18	PTN_MK_N	pfam domains	PF05196	2	1	17795	50	PTN
5.612e-03	-5.18	Formin_GBD_N	pfam domains	PF18382	2	1	17795	50	FHOD3
5.612e-03	-5.18	AstE_AspA	pfam domains	PF04952	2	1	17795	50	ASPA
5.612e-03	-5.18	EF-hand_Zip	pfam domains	PF21116	2	1	17795	50	SLC39A12
5.612e-03	-5.18	ZIP4_domain	pfam domains	PF18292	2	1	17795	50	SLC39A12
5.624e-03	-5.18	follicular_lymphoma	COSMIC cancer mutations	follicular_lymphoma	1209	9	16828	47	NCKAP5,AQP4,PRDM16,SORCS2,SOX5,DGKB,RORA,FHOD3,GPC5
5.632e-03	-5.18	Signaling by Overexpressed Wild-Type EGFR in Cancer	REACTOME pathways	R-HSA-5638302	2	1	10285	29	EGF
5.632e-03	-5.18	Inhibition of Signaling by Overexpressed EGFR	REACTOME pathways	R-HSA-5638303	2	1	10285	29	EGF
5.632e-03	-5.18	Transport of connexons to the plasma membrane	REACTOME pathways	R-HSA-190872	2	1	10285	29	GJA1
5.657e-03	-5.17	African trypanosomiasis	KEGG pathways	hsa05143	34	2	7161	24	APOA1,LAMA4
5.657e-03	-5.17	African trypanosomiasis	KEGG pathways	ko05143	34	2	7161	24	APOA1,LAMA4
5.658e-03	-5.17	mesothelioma	COSMIC cancer mutations	mesothelioma	4477	21	16828	47	BCAR3,LPIN2,AMOT,QKI,PTPRZ1,MSI2,RORA,FKBP5,USP6NL,FARP1,GRK5,SNTB1,PRDM16,PREX1,SOX5,FGFR3,DGKB,LRIG1,PREX2,GPM6B,TRPS1
5.685e-03	-5.17	endometrium-carcinoma-serous_carcinoma	COSMIC cancer mutations	endometrium-carcinoma-serous_carcinoma	1442	10	16828	47	GPC5,FHOD3,TRPS1,DGKB,FARP1,PRDM16,SLC4A4,AMOT,EGF,NCKAP5
5.706e-03	-5.17	USP8 (ubiquitin specific peptidase 8)	protein interactions	9101	144	3	19454	49	LRIG1,PRKN,GJA1
5.706e-03	-5.17	PH_domain	interpro domains	IPR001849	266	4	18521	50	FARP1,SNTB1,PREX1,PREX2
5.742e-03	-5.16	skin-leg-malignant_melanoma-nodular	COSMIC cancer mutations	skin-leg-malignant_melanoma-nodular	258	4	16828	47	PTPRZ1,EGF,GRK5,SLC4A4
5.742e-03	-5.16	PRKD3 (protein kinase D3)	protein interactions	23683	45	2	19454	49	FKBP5,PRKN
5.742e-03	-5.16	ARAP1 (ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1)	protein interactions	116985	45	2	19454	49	FGFR3,PRKN
5.742e-03	-5.16	SMARCAL1 (SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a like 1)	protein interactions	50485	45	2	19454	49	FKBP5,PRKN
5.766e-03	-5.16	SERPINH1 (serpin family H member 1)	protein interactions	871	286	4	19454	49	FKBP5,CTBP1,FGFR3,PRKN
5.784e-03	-5.15	phosphatase activity	molecular function	GO:0016791	272	4	18094	48	PTPRZ1,PLPP3,LPIN2,TNS3
5.816e-03	-5.15	ACAD11 (acyl-CoA dehydrogenase family member 11)	protein interactions	84129	145	3	19454	49	PRKN,AMOT,SOX5
5.836e-03	-5.14	NAT10 (N-acetyltransferase 10)	protein interactions	55226	287	4	19454	49	FKBP5,PRDM16,PRKN,GRK5
5.836e-03	-5.14	PARD3 (par-3 family cell polarity regulator)	protein interactions	56288	287	4	19454	49	USP6NL,AMOT,GJA1,FARP1
5.859e-03	-5.14	GTPase activator activity	molecular function	GO:0005096	273	4	18094	48	PREX2,USP6NL,PREX1,ADGRB3
5.928e-03	-5.13	SAV1 (salvador family WW domain containing protein 1)	protein interactions	60485	146	3	19454	49	SNTB1,PRKN,AMOT
5.929e-03	-5.13	postsynapse	cellular component	GO:0098794	646	6	19108	49	DGKB,ADGRB3,PRKN,SORCS2,SLC6A11,FARP1
5.935e-03	-5.13	triglyceride homeostasis	biological process	GO:0070328	42	2	18204	50	RORA,APOA1
5.935e-03	-5.13	regulation of protein localization to cell surface	biological process	GO:2000008	42	2	18204	50	GPM6B,EGF
5.941e-03	-5.13	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-mantle_cell_lymphoma	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-mantle_cell_lymphoma	2737	15	16828	47	SORCS2,NCKAP5,RFX4,GPC5,FARP1,SLC1A3,ELOVL2,PREX1,PRDM16,SOX5,SLC1A2,TRPS1,PREX2,DGKB,LRIG1
5.978e-03	-5.12	PH-like_dom_sf	interpro domains	IPR011993	431	5	18521	50	TNS3,FARP1,PREX1,SNTB1,PREX2
5.994e-03	-5.12	RADX (RPA1 related single stranded DNA binding protein, X-linked)	protein interactions	55086	46	2	19454	49	PRKN,FKBP5
5.998e-03	-5.12	growth	biological process	GO:0040007	424	5	18204	50	FGFR3,GJA1,PTN,SLC1A2,SLC39A12
5.998e-03	-5.12	developmental growth	biological process	GO:0048589	424	5	18204	50	SLC39A12,PTN,SLC1A2,GJA1,FGFR3
6.041e-03	-5.11	PIP5K1A (phosphatidylinositol-4-phosphate 5-kinase type 1 alpha)	protein interactions	8394	147	3	19454	49	PRKN,PREX1,GJA1
6.041e-03	-5.11	TFAP4 (transcription factor AP-4)	protein interactions	7023	147	3	19454	49	CTBP1,NFIA,PRDM16
6.062e-03	-5.11	organic acid transmembrane transport	biological process	GO:1903825	135	3	18204	50	SLC6A11,SLC1A2,SLC1A3
6.064e-03	-5.11	I-set	pfam domains	PF07679	132	3	17795	50	LRIG1,FGFRL1,FGFR3
6.087e-03	-5.10	regulation of cellular component biogenesis	biological process	GO:0044087	1016	8	18204	50	SLC39A12,APOA1,USP6NL,PREX1,PRKN,GPM6B,FARP1,ADGRB3
6.130e-03	-5.09	central_nervous_system-brain-glioma-astrocytoma_Grade_II	COSMIC cancer mutations	central_nervous_system-brain-glioma-astrocytoma_Grade_II	420	5	16828	47	PREX1,FGFR3,ZBTB20,GJA1,FARP1
6.141e-03	-5.09	metal ion transmembrane transporter activity	molecular function	GO:0046873	442	5	18094	48	SLC6A11,SLC1A2,SLC39A12,SLC4A4,SLC1A3
6.155e-03	-5.09	ATXN1L (ataxin 1 like)	protein interactions	342371	148	3	19454	49	NFIA,SOX5,CTBP1
6.213e-03	-5.08	acylglycerol homeostasis	biological process	GO:0055090	43	2	18204	50	APOA1,RORA
6.213e-03	-5.08	positive regulation of substrate adhesion-dependent cell spreading	biological process	GO:1900026	43	2	18204	50	APOA1,PREX1
6.213e-03	-5.08	bone remodeling	biological process	GO:0046849	43	2	18204	50	GJA1,PTN
6.250e-03	-5.08	SACS (sacsin molecular chaperone)	protein interactions	26278	47	2	19454	49	FKBP5,PRKN
6.250e-03	-5.08	KIF3B (kinesin family member 3B)	protein interactions	9371	47	2	19454	49	NCKAP5,PRKN
6.250e-03	-5.08	LRIG3 (leucine rich repeats and immunoglobulin like domains 3)	protein interactions	121227	47	2	19454	49	LRIG1,GJA1
6.257e-03	-5.07	active transmembrane transporter activity	molecular function	GO:0022804	444	5	18094	48	SLC4A4,SLC1A3,SLC1A2,SLC39A12,SLC6A11
6.260e-03	-5.07	astrocytoma_Grade_II	COSMIC cancer mutations	astrocytoma_Grade_II	601	6	16828	47	GJA1,ZBTB20,FARP1,PREX2,PREX1,FGFR3
6.288e-03	-5.07	basal plasma membrane	cellular component	GO:0009925	288	4	19108	49	SLC1A3,PLPP3,AQP4,SLC4A4
6.297e-03	-5.07	response to xenobiotic stimulus	biological process	GO:0009410	429	5	18204	50	RORA,SLC6A11,SLC1A3,BCAR3,SLC1A2
6.324e-03	-5.06	monoatomic anion transmembrane transporter activity	molecular function	GO:0008509	142	3	18094	48	SLC1A2,SLC6A11,SLC4A4
6.387e-03	-5.05	KDM2B (lysine demethylase 2B)	protein interactions	84678	150	3	19454	49	NFIA,SOX5,CTBP1
6.388e-03	-5.05	Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)	gene3d domains	2.30.29.30	431	5	14470	40	SNTB1,FARP1,TNS3,PREX2,PREX1
6.391e-03	-5.05	D_2_HYDROXYACID_DH_1	prosite domains	PS00065	2	1	12186	39	CTBP1
6.391e-03	-5.05	PTN_MK_1	prosite domains	PS00619	2	1	12186	39	PTN
6.391e-03	-5.05	PTN_MK_2	prosite domains	PS00620	2	1	12186	39	PTN
6.420e-03	-5.05	response to wounding	biological process	GO:0009611	431	5	18204	50	SLC1A2,SLC1A3,NFIA,PLPP3,DGKB
6.441e-03	-5.05	membrane raft	cellular component	GO:0045121	290	4	19108	49	GJA1,GPM6B,PLPP3,SLC1A2
6.441e-03	-5.04	regulation of generation of precursor metabolites and energy	biological process	GO:0043467	138	3	18204	50	PRDM16,ZBTB20,SLC4A4
6.498e-03	-5.04	positive regulation of bone mineralization	biological process	GO:0030501	44	2	18204	50	GPM6B,PTN
6.574e-03	-5.02	actin filament-based process	biological process	GO:0030029	616	6	18204	50	QKI,FHOD3,FARP1,PREX1,AMOT,GJA1
6.576e-03	-5.02	SP7 (Sp7 transcription factor)	protein interactions	121340	297	4	19454	49	NFIA,TRPS1,QKI,SOX5
6.597e-03	-5.02	membrane microdomain	cellular component	GO:0098857	292	4	19108	49	GJA1,GPM6B,PLPP3,SLC1A2
6.624e-03	-5.02	TRIP11 (thyroid hormone receptor interactor 11)	protein interactions	9321	152	3	19454	49	FGFR3,PRKN,GJA1
6.645e-03	-5.01	(4Z,7Z,10Z,13Z,16Z)-docosa-4,7,10,13,16-pentaenoate biosynthesis II (4-desaturase)	BIOCYC pathways	META_PWY-7728	3	1	902	2	ELOVL2
6.645e-03	-5.01	docosahexaenoate biosynthesis III (mammals)	BIOCYC pathways	HUMAN_PWY-7606	3	1	902	2	ELOVL2
6.645e-03	-5.01	docosahexaenoate biosynthesis IV (4-desaturase, mammals)	BIOCYC pathways	META_PWY-7727	3	1	902	2	ELOVL2
6.659e-03	-5.01	enzyme regulator activity	molecular function	GO:0030234	1305	9	18094	48	USP6NL,PREX2,PTN,BCAR3,ADGRB3,PREX1,APOA1,EGF,FARP1
6.670e-03	-5.01	blood vessel morphogenesis	biological process	GO:0048514	435	5	18204	50	QKI,EGF,GJA1,RORA,AMOT
6.749e-03	-5.00	Retinoid metabolism and transport	REACTOME pathways	R-HSA-975634	44	2	10285	29	APOA1,GPC5
6.777e-03	-4.99	TNFAIP8L1 (TNF alpha induced protein 8 like 1)	protein interactions	126282	49	2	19454	49	GRK5,PRKN
6.777e-03	-4.99	GCNT2 (glucosaminyl (N-acetyl) transferase 2 (I blood group))	protein interactions	2651	49	2	19454	49	PRKN,CTBP1
6.876e-03	-4.98	PTNMIDKINE	prints domains	PR00269	2	1	5227	18	PTN
6.890e-03	-4.98	learning or memory	biological process	GO:0007611	276	4	18204	50	ADGRB3,PRKN,PTPRZ1,PTN
6.904e-03	-4.98	transcription corepressor binding	molecular function	GO:0001222	47	2	18094	48	RORA,CTBP1
6.969e-03	-4.97	monoatomic anion transmembrane transport	biological process	GO:0098656	142	3	18204	50	SLC4A4,SLC1A2,SLC1A3
6.969e-03	-4.97	positive regulation of small molecule metabolic process	biological process	GO:0062013	142	3	18204	50	ZBTB20,APOA1,SLC4A4
6.986e-03	-4.96	PTN	smart domains	SM00193	2	1	9717	34	PTN
6.990e-03	-4.96	VPS45 (vacuolar protein sorting 45 homolog)	protein interactions	11311	155	3	19454	49	PRKN,BCAR3,GJA1
7.002e-03	-4.96	third_ventricle	COSMIC cancer mutations	third_ventricle	45	2	16828	47	FGFR3,QKI
7.010e-03	-4.96	prostate-carcinoma-adenocarcinoma	COSMIC cancer mutations	prostate-carcinoma-adenocarcinoma	12379	42	16828	47	ASPA,SORCS2,CTBP1,NPAS3,PTPRZ1,RFX4,SLC6A11,TNS3,GPC5,SLC1A3,USP6NL,SLC39A12,FGFRL1,SOX5,EGF,SNTB1,GRK5,TRPS1,GPM6B,DGKB,LRIG1,AQP4,QKI,NCKAP5,GJA1,BCAR3,UNC93A,NHSL1,FARP1,PTN,FKBP5,ZBTB20,RORA,FGFR3,ELOVL2,PRDM16,PREX1,LAMA4,SLC1A2,FHOD3,PREX2,NFIA
7.049e-03	-4.95	ZNF516 (zinc finger protein 516)	protein interactions	9658	50	2	19454	49	CTBP1,PRDM16
7.049e-03	-4.95	ANXA3 (annexin A3)	protein interactions	306	50	2	19454	49	PRKN,FGFR3
7.065e-03	-4.95	regulation of GTPase activity	biological process	GO:0043087	278	4	18204	50	PREX1,USP6NL,PREX2,BCAR3
7.084e-03	-4.95	regulation of myelination	biological process	GO:0031641	46	2	18204	50	PTPRZ1,PTN
7.115e-03	-4.95	ABCF2 (ATP binding cassette subfamily F member 2)	protein interactions	10061	156	3	19454	49	FGFR3,PRKN,PRDM16
7.175e-03	-4.94	PDZ	interpro domains	IPR001478	146	3	18521	50	PREX2,SNTB1,PREX1
7.191e-03	-4.93	cell morphogenesis involved in neuron differentiation	biological process	GO:0048667	443	5	18204	50	PTN,PREX2,SLC1A3,PTPRZ1,FARP1
7.241e-03	-4.93	ACOT9 (acyl-CoA thioesterase 9)	protein interactions	23597	157	3	19454	49	FKBP5,PRKN,FGFR3
7.263e-03	-4.93	cellular response to oxygen-containing compound	biological process	GO:1901701	1047	8	18204	50	SLC1A2,BCAR3,LPIN2,SLC1A3,GJA1,RORA,PRKN,ZBTB20
7.272e-03	-4.92	Ig_3	pfam domains	PF13927	141	3	17795	50	LRIG1,FGFRL1,FGFR3
7.342e-03	-4.91	adrenal_cortical_carcinoma	COSMIC cancer mutations	adrenal_cortical_carcinoma	2256	13	16828	47	PTPRZ1,NCKAP5,RFX4,LPIN2,FARP1,ZBTB20,SLC6A11,NHSL1,TNS3,GRK5,SLC1A2,SOX5,LRIG1
7.368e-03	-4.91	GJA8 (gap junction protein alpha 8)	protein interactions	2703	158	3	19454	49	UNC93A,GJA1,AQP4
7.423e-03	-4.90	RCOR1 (REST corepressor 1)	protein interactions	23186	487	5	19454	49	PRDM16,TRPS1,AMOT,SOX5,CTBP1
7.493e-03	-4.89	cell surface	cellular component	GO:0009986	896	7	19108	49	GPC5,FGFR3,AMOT,SLC1A2,AQP4,SLC4A4,SLC1A3
7.496e-03	-4.89	APOA1 (apolipoprotein A1)	protein interactions	335	159	3	19454	49	TNS3,APOA1,GJA1
7.521e-03	-4.89	adult behavior	biological process	GO:0030534	146	3	18204	50	SLC1A2,PREX2,PRKN
7.538e-03	-4.89	MROH2A (maestro heat like repeat family member 2A)	protein interactions	339766	3	1	19454	49	PRKN
7.538e-03	-4.89	IL34 (interleukin 34)	protein interactions	146433	3	1	19454	49	PTPRZ1
7.538e-03	-4.89	WDR64 (WD repeat domain 64)	protein interactions	128025	3	1	19454	49	PRKN
7.538e-03	-4.89	LINC02907 (long intergenic non-protein coding RNA 2907)	protein interactions	157927	3	1	19454	49	PRKN
7.538e-03	-4.89	SMPDL3A (sphingomyelin phosphodiesterase acid like 3A)	protein interactions	10924	3	1	19454	49	APOA1
7.538e-03	-4.89	IQSEC3 (IQ motif and Sec7 domain ArfGEF 3)	protein interactions	440073	3	1	19454	49	PRKN
7.538e-03	-4.89	ADGRG4 (adhesion G protein-coupled receptor G4)	protein interactions	139378	3	1	19454	49	PRKN
7.538e-03	-4.89	C4orf36 (chromosome 4 open reading frame 36)	protein interactions	132989	3	1	19454	49	PRKN
7.538e-03	-4.89	SLC4A11 (solute carrier family 4 member 11)	protein interactions	83959	3	1	19454	49	PRKN
7.538e-03	-4.89	VWA3A (von Willebrand factor A domain containing 3A)	protein interactions	146177	3	1	19454	49	PRKN
7.538e-03	-4.89	FBXO39 (F-box protein 39)	protein interactions	162517	3	1	19454	49	PRKN
7.538e-03	-4.89	APOL1 (apolipoprotein L1)	protein interactions	8542	3	1	19454	49	APOA1
7.538e-03	-4.89	ERV3-1 (endogenous retrovirus group 3 member 1, envelope)	protein interactions	2086	3	1	19454	49	PRKN
7.538e-03	-4.89	TTLL13 (tubulin tyrosine ligase like 13)	protein interactions	440307	3	1	19454	49	PRKN
7.538e-03	-4.89	LRRC71 (leucine rich repeat containing 71)	protein interactions	149499	3	1	19454	49	PRKN
7.538e-03	-4.89	MROH9 (maestro heat like repeat family member 9)	protein interactions	80133	3	1	19454	49	PRKN
7.538e-03	-4.89	SLC6A17 (solute carrier family 6 member 17)	protein interactions	388662	3	1	19454	49	PRKN
7.538e-03	-4.89	E1A (control protein E1A;control protein E1A 243R)	protein interactions	2652980	3	1	19454	49	CTBP1
7.538e-03	-4.89	PDPK2P (3-phosphoinositide dependent protein kinase 2, pseudogene)	protein interactions	653650	3	1	19454	49	PRKN
7.538e-03	-4.89	CNTD1 (cyclin N-terminal domain containing 1)	protein interactions	124817	3	1	19454	49	PRKN
7.538e-03	-4.89	Mfn2 (mitofusin 2)	protein interactions	170731	3	1	19454	49	PRKN
7.538e-03	-4.89	CDH26 (cadherin 26)	protein interactions	60437	3	1	19454	49	PRKN
7.538e-03	-4.89	Phum_PHUM577390 (serine/threonine-protein kinase PINK1, putative)	protein interactions	8239562	3	1	19454	49	PRKN
7.538e-03	-4.89	Lep (leptin)	protein interactions	16846	3	1	19454	49	APOA1
7.538e-03	-4.89	CT45A6 (cancer/testis antigen family 45 member A6)	protein interactions	541465	3	1	19454	49	PRKN
7.538e-03	-4.89	cbx2.L (chromobox 2 L homeolog)	protein interactions	398110	3	1	19454	49	CTBP1
7.538e-03	-4.89	DEFB124 (defensin beta 124)	protein interactions	245937	3	1	19454	49	GJA1
7.538e-03	-4.89	FAM83C (family with sequence similarity 83 member C)	protein interactions	128876	3	1	19454	49	APOA1
7.538e-03	-4.89	Eps15 (epidermal growth factor receptor pathway substrate 15)	protein interactions	313474	3	1	19454	49	PRKN
7.538e-03	-4.89	OR1L3 (olfactory receptor family 1 subfamily L member 3)	protein interactions	26735	3	1	19454	49	PRKN
7.587e-03	-4.88	PDZ_sf	interpro domains	IPR036034	149	3	18521	50	PREX2,PREX1,SNTB1
7.605e-03	-4.88	OSGIN1 (oxidative stress induced growth inhibitor 1)	protein interactions	29948	52	2	19454	49	PRKN,BCAR3
7.626e-03	-4.88	SOX5 (SRY-box transcription factor 5)	protein interactions	6660	160	3	19454	49	SOX5,NFIA,TRPS1
7.631e-03	-4.88	human chr8q23.3	chromosome location	human chr8q23.3	4	1	26134	50	TRPS1
7.658e-03	-4.87	PH_DOMAIN	prosite domains	PS50003	246	4	12186	39	SNTB1,PREX1,PREX2,FARP1
7.674e-03	-4.87	Parkin-FBXW7-Cul1 ubiquitin ligase complex	cellular component	GO:1990452	3	1	19108	49	PRKN
7.674e-03	-4.87	mitochondrion-derived vesicle	cellular component	GO:0099073	3	1	19108	49	PRKN
7.677e-03	-4.87	HADHA (hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit alpha)	protein interactions	3030	491	5	19454	49	LAMA4,FARP1,FGFR3,PRKN,PRDM16
7.694e-03	-4.87	negative regulation of cold-induced thermogenesis	biological process	GO:0120163	48	2	18204	50	QKI,LAMA4
7.793e-03	-4.85	developmental maturation	biological process	GO:0021700	286	4	18204	50	GJA1,FGFR3,ADGRB3,NFIA
7.800e-03	-4.85	clear_cell_renal_cell_carcinoma	COSMIC cancer mutations	clear_cell_renal_cell_carcinoma	13924	45	16828	47	BCAR3,FARP1,RORA,PTN,PRDM16,NFIA,PREX2,PTPRZ1,CTBP1,LPIN2,MSI2,USP6NL,SLC1A3,GPC5,TNS3,EGF,GRK5,SLC39A12,NCKAP5,QKI,GJA1,AQP4,ZBTB20,FKBP5,UNC93A,NHSL1,SLC1A2,ELOVL2,FGFR3,LAMA4,PREX1,FHOD3,NPAS3,AMOT,ASPA,SORCS2,SLC6A11,SNTB1,SLC4A4,FGFRL1,SOX5,LRIG1,DGKB,TRPS1,GPM6B
7.800e-03	-4.85	kidney-carcinoma-clear_cell_renal_cell_carcinoma	COSMIC cancer mutations	kidney-carcinoma-clear_cell_renal_cell_carcinoma	13924	45	16828	47	FHOD3,SLC1A2,PREX1,LAMA4,FGFR3,ELOVL2,ZBTB20,FKBP5,NHSL1,UNC93A,GJA1,QKI,NCKAP5,AQP4,DGKB,LRIG1,GPM6B,TRPS1,SNTB1,FGFRL1,SOX5,SLC4A4,SLC6A11,AMOT,NPAS3,SORCS2,ASPA,PREX2,NFIA,PRDM16,PTN,RORA,FARP1,BCAR3,GRK5,EGF,SLC39A12,SLC1A3,USP6NL,TNS3,GPC5,LPIN2,CTBP1,PTPRZ1,MSI2
7.847e-03	-4.85	basal part of cell	cellular component	GO:0045178	307	4	19108	49	SLC1A3,SLC4A4,AQP4,PLPP3
7.888e-03	-4.84	ossification	biological process	GO:0001503	287	4	18204	50	GJA1,FGFR3,GPM6B,PTN
7.891e-03	-4.84	RIPK3 (receptor interacting serine/threonine kinase 3)	protein interactions	11035	53	2	19454	49	FKBP5,PRKN
7.938e-03	-4.84	F-box domain binding	molecular function	GO:1990444	3	1	18094	48	PRKN
7.938e-03	-4.84	ceramide-1-phosphate phosphatase activity	molecular function	GO:0106235	3	1	18094	48	PLPP3
7.938e-03	-4.84	high-density lipoprotein particle receptor binding	molecular function	GO:0070653	3	1	18094	48	APOA1
7.938e-03	-4.84	taurine:sodium symporter activity	molecular function	GO:0005369	3	1	18094	48	SLC6A11
7.938e-03	-4.84	cysteine transmembrane transporter activity	molecular function	GO:0033229	3	1	18094	48	SLC1A2
7.974e-03	-4.83	SMG7 (SMG7 nonsense mediated mRNA decay factor)	protein interactions	9887	314	4	19454	49	TRPS1,PRKN,FGFR3,AMOT
7.997e-03	-4.83	chest	COSMIC cancer mutations	chest	147	3	16828	47	PREX2,SLC6A11,FGFR3
8.001e-03	-4.83	-	gene3d domains	2.30.42.10	149	3	14470	40	SNTB1,PREX1,PREX2
8.007e-03	-4.83	oligodendrocyte development	biological process	GO:0014003	49	2	18204	50	ASPA,GPM6B
8.024e-03	-4.83	ANK3 (ankyrin 3)	protein interactions	288	163	3	19454	49	PRKN,FARP1,GJA1
8.078e-03	-4.82	LIPIN	interpro domains	IPR026058	3	1	18521	50	LPIN2
8.078e-03	-4.82	AGRB_N	interpro domains	IPR043838	3	1	18521	50	ADGRB3
8.078e-03	-4.82	Connexin_C	interpro domains	IPR034634	3	1	18521	50	GJA1
8.078e-03	-4.82	Lipin_mid	interpro domains	IPR031703	3	1	18521	50	LPIN2
8.078e-03	-4.82	Angiomotin	interpro domains	IPR009114	3	1	18521	50	AMOT
8.078e-03	-4.82	DGK_typeI_N_sf	interpro domains	IPR038199	3	1	18521	50	DGKB
8.078e-03	-4.82	PHsplit_syntrophin	interpro domains	IPR041428	3	1	18521	50	SNTB1
8.078e-03	-4.82	DAG_kinase_typeI_N	interpro domains	IPR029477	3	1	18521	50	DGKB
8.078e-03	-4.82	FARP1/FARP2/FRMD7_FERM_C	interpro domains	IPR041788	3	1	18521	50	FARP1
8.078e-03	-4.82	NR_DBD_ROR	interpro domains	IPR044101	3	1	18521	50	RORA
8.078e-03	-4.82	Tensin-like_SH2	interpro domains	IPR035012	3	1	18521	50	TNS3
8.078e-03	-4.82	ROR_rcpt	interpro domains	IPR003079	3	1	18521	50	RORA
8.078e-03	-4.82	SH2_SHEP1/BCAR3/NSP1	interpro domains	IPR044102	3	1	18521	50	BCAR3
8.078e-03	-4.82	Myelin_PLP	interpro domains	IPR001614	3	1	18521	50	GPM6B
8.078e-03	-4.82	Angiomotin_C	interpro domains	IPR024646	3	1	18521	50	AMOT
8.078e-03	-4.82	LNS2	interpro domains	IPR013209	3	1	18521	50	LPIN2
8.078e-03	-4.82	GPCR_2_brain_angio_inhib	interpro domains	IPR008077	3	1	18521	50	ADGRB3
8.078e-03	-4.82	Lipin_N	interpro domains	IPR007651	3	1	18521	50	LPIN2
8.078e-03	-4.82	Myelin_PLP_CS	interpro domains	IPR018237	3	1	18521	50	GPM6B
8.078e-03	-4.82	D-isomer_DH_CS1	interpro domains	IPR029752	3	1	18521	50	CTBP1
8.079e-03	-4.82	muscle cell differentiation	biological process	GO:0042692	289	4	18204	50	ADGRB3,FHOD3,QKI,RORA
8.085e-03	-4.82	signaling	biological process	GO:0023052	4968	22	18204	50	SLC1A3,APOA1,GJA1,SLC1A2,BCAR3,EGF,FARP1,PTN,PREX2,GRK5,FGFR3,PLPP3,FGFRL1,SLC39A12,SORCS2,PRKN,PREX1,RORA,NFIA,ADGRB3,AMOT,DGKB
8.088e-03	-4.82	amino acid binding	molecular function	GO:0016597	51	2	18094	48	SLC1A3,SLC6A11
8.097e-03	-4.82	regulation of nervous system development	biological process	GO:0051960	456	5	18204	50	PTPRZ1,PTN,ASPA,QKI,ADGRB3
8.136e-03	-4.81	SLC-mediated transmembrane transport	REACTOME pathways	R-HSA-425407	287	4	10285	29	SLC1A3,SLC6A11,SLC1A2,SLC4A4
8.151e-03	-4.81	Fat digestion and absorption	KEGG pathways	ko04975	41	2	7161	24	PLPP3,APOA1
8.151e-03	-4.81	Bladder cancer	KEGG pathways	hsa05219	41	2	7161	24	FGFR3,EGF
8.151e-03	-4.81	Bladder cancer	KEGG pathways	ko05219	41	2	7161	24	EGF,FGFR3
8.151e-03	-4.81	Fat digestion and absorption	KEGG pathways	hsa04975	41	2	7161	24	PLPP3,APOA1
8.181e-03	-4.81	NOS1 (nitric oxide synthase 1)	protein interactions	4842	54	2	19454	49	CTBP1,SNTB1
8.181e-03	-4.81	LONP2 (lon peptidase 2, peroxisomal)	protein interactions	83752	54	2	19454	49	AMOT,PRKN
8.181e-03	-4.81	DCXR (dicarbonyl and L-xylulose reductase)	protein interactions	51181	54	2	19454	49	PRKN,FGFR3
8.181e-03	-4.81	NSUN5 (NOP2/Sun RNA methyltransferase 5)	protein interactions	55695	54	2	19454	49	PRKN,FKBP5
8.181e-03	-4.81	EPM2A (EPM2A glucan phosphatase, laforin)	protein interactions	7957	54	2	19454	49	FKBP5,PREX1
8.218e-03	-4.80	mitochondrion-derived vesicle mediated transport	biological process	GO:0099075	3	1	18204	50	PRKN
8.218e-03	-4.80	negative regulation of serotonin uptake	biological process	GO:0051612	3	1	18204	50	GPM6B
8.218e-03	-4.80	cell communication by chemical coupling	biological process	GO:0010643	3	1	18204	50	GJA1
8.218e-03	-4.80	regulation of endoplasmic reticulum stress-induced neuron intrinsic apoptotic signaling pathway	biological process	GO:1903381	3	1	18204	50	PRKN
8.218e-03	-4.80	positive regulation of mitochondrial fusion	biological process	GO:0010636	3	1	18204	50	PRKN
8.218e-03	-4.80	establishment of cell polarity involved in ameboidal cell migration	biological process	GO:0003365	3	1	18204	50	AMOT
8.218e-03	-4.80	cysteine transport	biological process	GO:0042883	3	1	18204	50	SLC1A2
8.218e-03	-4.80	mitochondrion to lysosome vesicle-mediated transport	biological process	GO:0099074	3	1	18204	50	PRKN
8.218e-03	-4.80	negative regulation of neurotransmitter uptake	biological process	GO:0051581	3	1	18204	50	GPM6B
8.218e-03	-4.80	acetate metabolic process	biological process	GO:0006083	3	1	18204	50	ASPA
8.218e-03	-4.80	cysteine transmembrane transport	biological process	GO:1903712	3	1	18204	50	SLC1A2
8.218e-03	-4.80	ossification involved in bone remodeling	biological process	GO:0043932	3	1	18204	50	PTN
8.239e-03	-4.80	LGALS1 (galectin 1)	protein interactions	3956	317	4	19454	49	LAMA4,PTPRZ1,FKBP5,PRKN
8.271e-03	-4.80	Diacylglycerol kinase alpha	gene3d domains	1.10.238.110	3	1	14470	40	DGKB
8.310e-03	-4.79	HNRNPL (heterogeneous nuclear ribonucleoprotein L)	protein interactions	3191	1958	11	19454	49	QKI,FGFRL1,FGFR3,PRKN,TRPS1,NFIA,MSI2,FKBP5,CTBP1,ZBTB20,FARP1
8.327e-03	-4.79	epidermal growth factor receptor signaling pathway	biological process	GO:0007173	50	2	18204	50	BCAR3,EGF
8.356e-03	-4.78	urinary_tract-bladder-papilloma	COSMIC cancer mutations	urinary_tract-bladder-papilloma	3	1	16828	47	FGFR3
8.356e-03	-4.78	skin-lentigo	COSMIC cancer mutations	skin-lentigo	3	1	16828	47	FGFR3
8.356e-03	-4.78	skin-forearm-lentigo	COSMIC cancer mutations	skin-forearm-lentigo	3	1	16828	47	FGFR3
8.356e-03	-4.78	lentigo	COSMIC cancer mutations	lentigo	3	1	16828	47	FGFR3
8.356e-03	-4.78	skin-leg-lentigo	COSMIC cancer mutations	skin-leg-lentigo	3	1	16828	47	FGFR3
8.356e-03	-4.78	skin-trunk-other-seborrhoeic_keratosis	COSMIC cancer mutations	skin-trunk-other-seborrhoeic_keratosis	3	1	16828	47	FGFR3
8.356e-03	-4.78	skin-trunk-lentigo	COSMIC cancer mutations	skin-trunk-lentigo	3	1	16828	47	FGFR3
8.356e-03	-4.78	skin-face-lentigo	COSMIC cancer mutations	skin-face-lentigo	3	1	16828	47	FGFR3
8.356e-03	-4.78	skin-hand-lentigo	COSMIC cancer mutations	skin-hand-lentigo	3	1	16828	47	FGFR3
8.356e-03	-4.78	skin-leg-other-seborrhoeic_keratosis	COSMIC cancer mutations	skin-leg-other-seborrhoeic_keratosis	3	1	16828	47	FGFR3
8.397e-03	-4.78	regulation of lipid transport	biological process	GO:0032368	152	3	18204	50	APOA1,EGF,PRKN
8.406e-03	-4.78	Lipin_N	pfam domains	PF04571	3	1	17795	50	LPIN2
8.406e-03	-4.78	LNS2	pfam domains	PF08235	3	1	17795	50	LPIN2
8.406e-03	-4.78	Angiomotin_C	pfam domains	PF12240	3	1	17795	50	AMOT
8.406e-03	-4.78	AGRB_N	pfam domains	PF19188	3	1	17795	50	ADGRB3
8.406e-03	-4.78	Lipin_mid	pfam domains	PF16876	3	1	17795	50	LPIN2
8.406e-03	-4.78	Myelin_PLP	pfam domains	PF01275	3	1	17795	50	GPM6B
8.406e-03	-4.78	PH_17	pfam domains	PF18012	3	1	17795	50	SNTB1
8.406e-03	-4.78	DAG_kinase_N	pfam domains	PF14513	3	1	17795	50	DGKB
8.434e-03	-4.78	STK38 (serine/threonine kinase 38)	protein interactions	11329	166	3	19454	49	GJA1,PRKN,GRK5
8.436e-03	-4.78	TCF7L2 mutants don't bind CTBP	REACTOME pathways	R-HSA-5339700	3	1	10285	29	CTBP1
8.436e-03	-4.78	Regulation of gap junction activity	REACTOME pathways	R-HSA-191650	3	1	10285	29	GJA1
8.436e-03	-4.78	Transport of connexins along the secretory pathway	REACTOME pathways	R-HSA-190827	3	1	10285	29	GJA1
8.436e-03	-4.78	c-src mediated regulation of Cx43 function and closure of gap junctions	REACTOME pathways	R-HSA-191647	3	1	10285	29	GJA1
8.436e-03	-4.78	Oligomerization of connexins into connexons	REACTOME pathways	R-HSA-190704	3	1	10285	29	GJA1
8.476e-03	-4.77	integrin binding	molecular function	GO:0005178	158	3	18094	48	PLPP3,PTPRZ1,PTN
8.514e-03	-4.77	lung-carcinoma-small_cell_carcinoma	COSMIC cancer mutations	lung-carcinoma-small_cell_carcinoma	9908	36	16828	47	GJA1,BCAR3,QKI,PTN,FKBP5,RORA,FARP1,UNC93A,PREX1,PRDM16,LAMA4,FGFR3,APOA1,PREX2,NFIA,FHOD3,AMOT,LPIN2,RFX4,NPAS3,PTPRZ1,MSI2,USP6NL,TNS3,GPC5,GRK5,EGF,SNTB1,FGFRL1,SOX5,SLC39A12,SLC4A4,DGKB,LRIG1,GPM6B,TRPS1
8.547e-03	-4.76	positive regulation of cellular metabolic process	biological process	GO:0031325	3164	16	18204	50	FGFR3,PLPP3,NPAS3,PRDM16,PRKN,ZBTB20,GJA1,RORA,LPIN2,EGF,QKI,NFIA,BCAR3,CTBP1,SLC4A4,RFX4
8.608e-03	-4.76	small_cell_carcinoma	COSMIC cancer mutations	small_cell_carcinoma	9913	36	16828	47	PREX2,NFIA,FHOD3,APOA1,PRDM16,PREX1,LAMA4,FGFR3,UNC93A,PTN,FKBP5,RORA,FARP1,GJA1,BCAR3,QKI,GPM6B,TRPS1,DGKB,LRIG1,FGFRL1,SOX5,SLC4A4,SLC39A12,GRK5,EGF,SNTB1,TNS3,GPC5,USP6NL,MSI2,RFX4,AMOT,LPIN2,NPAS3,PTPRZ1
8.642e-03	-4.75	mantle_cell_lymphoma	COSMIC cancer mutations	mantle_cell_lymphoma	2849	15	16828	47	RFX4,NCKAP5,SORCS2,SLC1A3,FARP1,GPC5,SLC1A2,PREX1,PRDM16,SOX5,ELOVL2,DGKB,LRIG1,PREX2,TRPS1
8.702e-03	-4.74	learning	biological process	GO:0007612	154	3	18204	50	ADGRB3,PRKN,PTN
8.713e-03	-4.74	GAB1 (GRB2 associated binding protein 1)	protein interactions	2549	168	3	19454	49	TNS3,BCAR3,GJA1
8.713e-03	-4.74	VPS51 (VPS51 subunit of GARP complex)	protein interactions	738	168	3	19454	49	PRKN,GJA1,CTBP1
8.855e-03	-4.73	PIAS2 (protein inhibitor of activated STAT 2)	protein interactions	9063	169	3	19454	49	PRKN,CTBP1,SOX5
8.873e-03	-4.72	carboxylic acid transport	biological process	GO:0046942	297	4	18204	50	GJA1,SLC6A11,SLC1A2,SLC1A3
8.893e-03	-4.72	RHOH (ras homolog family member H)	protein interactions	399	509	5	19454	49	USP6NL,PRKN,FARP1,GJA1,PREX1
8.941e-03	-4.72	Bladder Cancer	WikiPathways	WP2828	32	2	5310	24	EGF,FGFR3
8.976e-03	-4.71	organic acid transport	biological process	GO:0015849	298	4	18204	50	SLC6A11,GJA1,SLC1A2,SLC1A3
8.978e-03	-4.71	cell communication	biological process	GO:0007154	5010	22	18204	50	SLC39A12,SORCS2,RORA,PREX1,PRKN,GRK5,FGFRL1,PLPP3,FGFR3,DGKB,AMOT,NFIA,ADGRB3,SLC1A3,APOA1,GJA1,PTN,PREX2,SLC1A2,BCAR3,FARP1,EGF
8.982e-03	-4.71	ERK1 and ERK2 cascade	biological process	GO:0070371	52	2	18204	50	EGF,APOA1
8.982e-03	-4.71	regulation of purine nucleotide catabolic process	biological process	GO:0033121	52	2	18204	50	ZBTB20,SLC4A4
8.982e-03	-4.71	regulation of glycolytic process	biological process	GO:0006110	52	2	18204	50	ZBTB20,SLC4A4
8.982e-03	-4.71	regulation of nucleotide catabolic process	biological process	GO:0030811	52	2	18204	50	SLC4A4,ZBTB20
8.999e-03	-4.71	GLMN (glomulin, FKBP associated protein)	protein interactions	11146	170	3	19454	49	FGFR3,PRDM16,FKBP5
8.999e-03	-4.71	PIK3C2A (phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 alpha)	protein interactions	5286	170	3	19454	49	PRKN,FKBP5,AMOT
9.070e-03	-4.70	KLF8 (KLF transcription factor 8)	protein interactions	11279	326	4	19454	49	NFIA,TRPS1,CTBP1,SOX5
9.081e-03	-4.70	RSU1 (Ras suppressor protein 1)	protein interactions	6251	57	2	19454	49	PRKN,FKBP5
9.081e-03	-4.70	ALG11 (ALG11 alpha-1,2-mannosyltransferase)	protein interactions	440138	57	2	19454	49	GPM6B,PRKN
9.081e-03	-4.70	CCDC18 (coiled-coil domain containing 18)	protein interactions	343099	57	2	19454	49	PRKN,AMOT
9.081e-03	-4.70	NR2F1 (nuclear receptor subfamily 2 group F member 1)	protein interactions	7025	57	2	19454	49	PRKN,GRK5
9.081e-03	-4.70	TRIM6 (tripartite motif containing 6)	protein interactions	117854	57	2	19454	49	APOA1,PRKN
9.129e-03	-4.70	positive regulation of catalytic activity	biological process	GO:0043085	868	7	18204	50	PREX2,PREX1,APOA1,USP6NL,BCAR3,EGF,FGFR3
9.137e-03	-4.70	anaplastic_carcinoma	COSMIC cancer mutations	anaplastic_carcinoma	856	7	16828	47	FHOD3,LAMA4,NFIA,SNTB1,FARP1,AMOT,GRK5
9.137e-03	-4.70	thyroid-carcinoma-anaplastic_carcinoma	COSMIC cancer mutations	thyroid-carcinoma-anaplastic_carcinoma	856	7	16828	47	FARP1,FHOD3,NFIA,SNTB1,AMOT,GRK5,LAMA4
9.143e-03	-4.69	PPFIBP1 (PPFIA binding protein 1)	protein interactions	8496	171	3	19454	49	PRKN,GRK5,GJA1
9.143e-03	-4.69	DDX47 (DEAD-box helicase 47)	protein interactions	51202	171	3	19454	49	PRKN,FGFR3,PRDM16
9.172e-03	-4.69	MAPT (microtubule associated protein tau)	protein interactions	4137	948	7	19454	49	FARP1,CTBP1,FKBP5,PRKN,SLC1A3,PLPP3,SLC1A2
9.254e-03	-4.68	RBM14 (RNA binding motif protein 14)	protein interactions	10432	514	5	19454	49	FGFR3,PRKN,PRDM16,CTBP1,QKI
9.273e-03	-4.68	NR3C1 (nuclear receptor subfamily 3 group C member 1)	protein interactions	2908	950	7	19454	49	NFIA,TRPS1,APOA1,SLC1A3,PREX1,ZBTB20,FKBP5
9.289e-03	-4.68	WDR26 (WD repeat domain 26)	protein interactions	80232	172	3	19454	49	PRKN,FGFR3,PRDM16
9.318e-03	-4.68	neutral amino acid transport	biological process	GO:0015804	53	2	18204	50	SLC1A2,SLC1A3
9.318e-03	-4.68	regulation of chondrocyte differentiation	biological process	GO:0032330	53	2	18204	50	TRPS1,SOX5
9.335e-03	-4.67	adenoma	COSMIC cancer mutations	adenoma	2873	15	16828	47	GPC5,SLC6A11,ZBTB20,PTN,FARP1,NCKAP5,PTPRZ1,NPAS3,FHOD3,LAMA4,SOX5,PREX1,PRDM16,FGFR3,EGF
9.358e-03	-4.67	NCOR1 (nuclear receptor corepressor 1)	protein interactions	9611	329	4	19454	49	PRKN,NFIA,SOX5,CTBP1
9.390e-03	-4.67	NAXE (NAD(P)HX epimerase)	protein interactions	128240	58	2	19454	49	PRKN,APOA1
9.390e-03	-4.67	DRG2 (developmentally regulated GTP binding protein 2)	protein interactions	1819	58	2	19454	49	PRKN,FKBP5
9.390e-03	-4.67	MANEA (mannosidase endo-alpha)	protein interactions	79694	58	2	19454	49	SLC39A12,LAMA4
9.390e-03	-4.67	PPWD1 (peptidylprolyl isomerase domain and WD repeat containing 1)	protein interactions	23398	58	2	19454	49	PRKN,FKBP5
9.390e-03	-4.67	CILK1 (ciliogenesis associated kinase 1)	protein interactions	22858	58	2	19454	49	MSI2,FKBP5
9.437e-03	-4.66	KRT16 (keratin 16)	protein interactions	3868	173	3	19454	49	PRKN,APOA1,AMOT
9.492e-03	-4.66	monoatomic anion transport	biological process	GO:0006820	159	3	18204	50	SLC1A2,SLC1A3,SLC4A4
9.530e-03	-4.65	human chr13q32.2	chromosome location	human chr13q32.2	5	1	26134	50	FARP1
9.571e-03	-4.65	MYELIN_PLP_2	prosite domains	PS01004	3	1	12186	39	GPM6B
9.571e-03	-4.65	MYELIN_PLP_1	prosite domains	PS00575	3	1	12186	39	GPM6B
9.586e-03	-4.65	SCYL2 (SCY1 like pseudokinase 2)	protein interactions	55681	174	3	19454	49	PRKN,GJA1,AMOT
9.659e-03	-4.64	positive regulation of biomineral tissue development	biological process	GO:0070169	54	2	18204	50	PTN,GPM6B
9.659e-03	-4.64	positive regulation of ossification	biological process	GO:0045778	54	2	18204	50	PTN,GPM6B
9.659e-03	-4.64	regulation of cholesterol efflux	biological process	GO:0010874	54	2	18204	50	EGF,APOA1
9.678e-03	-4.64	Metabolism of fat-soluble vitamins	REACTOME pathways	R-HSA-6806667	53	2	10285	29	GPC5,APOA1
9.704e-03	-4.64	KDM4B (lysine demethylase 4B)	protein interactions	23030	59	2	19454	49	PRKN,FKBP5
9.704e-03	-4.64	HBA1 (hemoglobin subunit alpha 1)	protein interactions	3039	59	2	19454	49	APOA1,PRKN
9.736e-03	-4.63	LHX3 (LIM homeobox 3)	protein interactions	8022	175	3	19454	49	TRPS1,NFIA,SOX5
9.819e-03	-4.62	positive regulation of peptidyl-tyrosine phosphorylation	biological process	GO:0050731	161	3	18204	50	PLPP3,FGFR3,EGF
9.827e-03	-4.62	regulation of small GTPase mediated signal transduction	biological process	GO:0051056	306	4	18204	50	PREX2,PREX1,AMOT,APOA1
9.887e-03	-4.62	AP3B1 (adaptor related protein complex 3 subunit beta 1)	protein interactions	8546	176	3	19454	49	FGFRL1,GRK5,PRKN
9.887e-03	-4.62	CDK11A (cyclin dependent kinase 11A)	protein interactions	728642	176	3	19454	49	FKBP5,APOA1,PRKN
1.001e-02	-4.60	response to cocaine	biological process	GO:0042220	55	2	18204	50	SLC1A3,SLC1A2
1.002e-02	-4.60	SNTB1 (syntrophin beta 1)	protein interactions	6641	60	2	19454	49	FGFR3,TNS3
1.002e-02	-4.60	CTNNAL1 (catenin alpha like 1)	protein interactions	8727	60	2	19454	49	TNS3,GJA1
1.002e-02	-4.60	CA2 (carbonic anhydrase 2)	protein interactions	760	60	2	19454	49	PRKN,SLC4A4
1.002e-02	-4.60	Znf_NHR/GATA	interpro domains	IPR013088	56	2	18521	50	TRPS1,RORA
1.004e-02	-4.60	MCTP1 (multiple C2 and transmembrane domain containing 1)	protein interactions	79772	4	1	19454	49	PRKN
1.004e-02	-4.60	NLRP13 (NLR family pyrin domain containing 13)	protein interactions	126204	4	1	19454	49	PRKN
1.004e-02	-4.60	PLEKHD1 (pleckstrin homology and coiled-coil domain containing D1)	protein interactions	400224	4	1	19454	49	PRKN
1.004e-02	-4.60	AVPR1A (arginine vasopressin receptor 1A)	protein interactions	552	4	1	19454	49	GRK5
1.004e-02	-4.60	BPIFA3 (BPI fold containing family A member 3)	protein interactions	128861	4	1	19454	49	PRKN
1.004e-02	-4.60	SP5 (Sp5 transcription factor)	protein interactions	389058	4	1	19454	49	PRKN
1.004e-02	-4.60	UNC5D (unc-5 netrin receptor D)	protein interactions	137970	4	1	19454	49	PRKN
1.004e-02	-4.60	TIGD2 (tigger transposable element derived 2)	protein interactions	166815	4	1	19454	49	PRKN
1.004e-02	-4.60	SPATA31G1 (SPATA31 subfamily G member 1)	protein interactions	138724	4	1	19454	49	PRKN
1.004e-02	-4.60	PRKACA (protein kinase cAMP-activated catalytic subunit alpha)	protein interactions	282322	4	1	19454	49	PRKN
1.004e-02	-4.60	WDSUB1 (WD repeat, sterile alpha motif and U-box domain containing 1)	protein interactions	151525	4	1	19454	49	PRKN
1.004e-02	-4.60	Nrip1 (nuclear receptor interacting protein 1)	protein interactions	268903	4	1	19454	49	CTBP1
1.004e-02	-4.60	ST18 (ST18 C2H2C-type zinc finger transcription factor)	protein interactions	9705	4	1	19454	49	PRKN
1.004e-02	-4.60	Nme2 (NME/NM23 nucleoside diphosphate kinase 2)	protein interactions	18103	4	1	19454	49	RORA
1.004e-02	-4.60	ACTL7A (actin like 7A)	protein interactions	10881	4	1	19454	49	PRKN
1.004e-02	-4.60	MYO1H (myosin IH)	protein interactions	283446	4	1	19454	49	PRKN
1.004e-02	-4.60	FAT2 (FAT atypical cadherin 2)	protein interactions	2196	4	1	19454	49	PRKN
1.004e-02	-4.60	EFCAB5 (EF-hand calcium binding domain 5)	protein interactions	374786	4	1	19454	49	PRKN
1.004e-02	-4.60	MATCAP1 (microtubule associated tyrosine carboxypeptidase 1)	protein interactions	653319	4	1	19454	49	PRKN
1.004e-02	-4.60	KANK3 (KN motif and ankyrin repeat domains 3)	protein interactions	256949	4	1	19454	49	PRKN
1.004e-02	-4.60	METTL25B (methyltransferase like 25B)	protein interactions	51093	4	1	19454	49	PRKN
1.004e-02	-4.60	FBXO48 (F-box protein 48)	protein interactions	554251	4	1	19454	49	PRKN
1.004e-02	-4.60	P2RY14 (purinergic receptor P2Y14)	protein interactions	9934	4	1	19454	49	PRKN
1.004e-02	-4.60	IGKV2-24 (immunoglobulin kappa variable 2-24)	protein interactions	28923	4	1	19454	49	PRKN
1.004e-02	-4.60	APOF (apolipoprotein F)	protein interactions	319	4	1	19454	49	APOA1
1.004e-02	-4.60	ERICH6B (glutamate rich 6B)	protein interactions	220081	4	1	19454	49	PRKN
1.004e-02	-4.60	Egfr (epidermal growth factor receptor)	protein interactions	13649	4	1	19454	49	PRKN
1.004e-02	-4.60	KIFBP (kinesin family binding protein)	protein interactions	26128	177	3	19454	49	FKBP5,PRKN,FGFR3
1.004e-02	-4.60	GATA3 (GATA binding protein 3)	protein interactions	2625	177	3	19454	49	QKI,NFIA,TRPS1
1.006e-02	-4.60	YWHAB (tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein beta)	protein interactions	7529	965	7	19454	49	GRK5,NHSL1,USP6NL,AMOT,TNS3,PRKN,FGFR3
1.009e-02	-4.60	C1_1	pfam domains	PF00130	54	2	17795	50	DGKB,TNS3
1.026e-02	-4.58	Transmembrane transport of small molecules	REACTOME pathways	R-HSA-382551	677	6	10285	29	SLC1A3,APOA1,SLC6A11,SLC4A4,SLC1A2,AQP4
1.026e-02	-4.58	ERBB3 (erb-b2 receptor tyrosine kinase 3)	protein interactions	2065	338	4	19454	49	BCAR3,EGF,LRIG1,TNS3
1.030e-02	-4.58	RORNUCRECPTR	prints domains	PR01293	3	1	5227	18	RORA
1.030e-02	-4.58	BAIPRECURSOR	prints domains	PR01694	3	1	5227	18	ADGRB3
1.030e-02	-4.58	ANGIOMOTIN	prints domains	PR01807	3	1	5227	18	AMOT
1.030e-02	-4.58	MYELINPLP	prints domains	PR00214	3	1	5227	18	GPM6B
1.032e-02	-4.57	parietal_lobe	COSMIC cancer mutations	parietal_lobe	55	2	16828	47	FGFR3,QKI
1.035e-02	-4.57	MAPK15 (mitogen-activated protein kinase 15)	protein interactions	225689	61	2	19454	49	FKBP5,PRKN
1.035e-02	-4.57	PTBP2 (polypyrimidine tract binding protein 2)	protein interactions	58155	61	2	19454	49	QKI,PRKN
1.043e-02	-4.56	adrenal_gland	COSMIC cancer mutations	adrenal_gland	2628	14	16828	47	RFX4,LPIN2,NCKAP5,PTPRZ1,ZBTB20,FARP1,NHSL1,TNS3,SLC6A11,GRK5,SLC1A2,SOX5,FGFR3,LRIG1
1.044e-02	-4.56	Erythroid Transcription Factor GATA-1, subunit A	gene3d domains	3.30.50.10	56	2	14470	40	TRPS1,RORA
1.046e-02	-4.56	PLP	smart domains	SM00002	3	1	9717	34	GPM6B
1.049e-02	-4.56	neuron projection morphogenesis	biological process	GO:0048812	486	5	18204	50	FARP1,PREX2,PTN,PTPRZ1,SLC39A12
1.049e-02	-4.56	import across plasma membrane	biological process	GO:0098739	165	3	18204	50	SLC1A2,SLC1A3,SLC39A12
1.051e-02	-4.56	VTN (vitronectin)	protein interactions	7448	180	3	19454	49	PRKN,EGF,NFIA
1.051e-02	-4.56	CYFIP1 (cytoplasmic FMR1 interacting protein 1)	protein interactions	23191	180	3	19454	49	PRDM16,PRKN,SLC1A3
1.051e-02	-4.56	MYOD1 (myogenic differentiation 1)	protein interactions	4654	180	3	19454	49	TRPS1,NFIA,RORA
1.057e-02	-4.55	beta-adrenergic receptor kinase activity	molecular function	GO:0047696	4	1	18094	48	GRK5
1.057e-02	-4.55	angiostatin binding	molecular function	GO:0043532	4	1	18094	48	AMOT
1.057e-02	-4.55	apolipoprotein A-I receptor binding	molecular function	GO:0034191	4	1	18094	48	APOA1
1.061e-02	-4.55	positive regulation of nucleobase-containing compound metabolic process	biological process	GO:0045935	2118	12	18204	50	NFIA,LPIN2,QKI,EGF,RFX4,SLC4A4,CTBP1,PRDM16,NPAS3,RORA,PRKN,ZBTB20
1.062e-02	-4.54	PDZ	prosite domains	PS50106	143	3	12186	39	PREX2,PREX1,SNTB1
1.067e-02	-4.54	ZKSCAN1 (zinc finger with KRAB and SCAN domains 1)	protein interactions	7586	62	2	19454	49	QKI,PRKN
1.067e-02	-4.54	MTMR7 (myotubularin related protein 7)	protein interactions	9108	62	2	19454	49	CTBP1,FKBP5
1.070e-02	-4.54	regulation of signaling	biological process	GO:0023051	3534	17	18204	50	AMOT,PTN,PREX2,EGF,GPC5,BCAR3,PREX1,PRKN,APOA1,RORA,GJA1,SLC1A3,SORCS2,PLPP3,FGFR3,PRDM16,GRK5
1.072e-02	-4.54	fibroblast growth factor receptor signaling pathway	biological process	GO:0008543	57	2	18204	50	FGFRL1,FGFR3
1.076e-02	-4.53	CTF/NFI	interpro domains	IPR000647	4	1	18521	50	NFIA
1.076e-02	-4.53	Tensin_PTB	interpro domains	IPR033929	4	1	18521	50	TNS3
1.076e-02	-4.53	FGF_rcpt_fam	interpro domains	IPR016248	4	1	18521	50	FGFR3
1.076e-02	-4.53	CTF/NFI_DNA-bd_N	interpro domains	IPR019548	4	1	18521	50	NFIA
1.076e-02	-4.53	D-isomer_DH_CS	interpro domains	IPR029753	4	1	18521	50	CTBP1
1.076e-02	-4.53	CTF/NFI_DNA-bd-dom	interpro domains	IPR020604	4	1	18521	50	NFIA
1.076e-02	-4.53	ApoA_E	interpro domains	IPR000074	4	1	18521	50	APOA1
1.076e-02	-4.53	D-isomer_2_OHA_DH_cat_dom	interpro domains	IPR006139	4	1	18521	50	CTBP1
1.076e-02	-4.53	CTF/NFI_DNA-bd_CS	interpro domains	IPR019739	4	1	18521	50	NFIA
1.076e-02	-4.53	D-isomer_DH_NAD-bd	interpro domains	IPR006140	4	1	18521	50	CTBP1
1.076e-02	-4.53	NHS-like	interpro domains	IPR024845	4	1	18521	50	NHSL1
1.080e-02	-4.53	tube morphogenesis	biological process	GO:0035239	685	6	18204	50	EGF,QKI,AMOT,GJA1,RORA,SLC39A12
1.084e-02	-4.52	stomach-adenocarcinoma	COSMIC cancer mutations	stomach-adenocarcinoma	4101	19	16828	47	PREX2,FHOD3,TRPS1,LRIG1,PREX1,SLC39A12,FGFR3,SLC4A4,SLC1A2,EGF,TNS3,GPC5,SLC6A11,PTN,FKBP5,RORA,ASPA,RFX4,QKI
1.092e-02	-4.52	regulation of cell communication	biological process	GO:0010646	3541	17	18204	50	EGF,BCAR3,GPC5,AMOT,PTN,PREX2,PLPP3,FGFR3,PRDM16,GRK5,PRKN,PREX1,APOA1,GJA1,RORA,SLC1A3,SORCS2
1.092e-02	-4.52	papillary_renal_cell_carcinoma	COSMIC cancer mutations	papillary_renal_cell_carcinoma	6364	26	16828	47	NFIA,PREX2,FHOD3,LAMA4,PRDM16,PREX1,FGFR3,UNC93A,RORA,ZBTB20,FARP1,BCAR3,NCKAP5,LRIG1,FGFRL1,SOX5,SLC4A4,GRK5,SNTB1,EGF,GPC5,TNS3,RFX4,LPIN2,AMOT,PTPRZ1
1.092e-02	-4.52	kidney-carcinoma-papillary_renal_cell_carcinoma	COSMIC cancer mutations	kidney-carcinoma-papillary_renal_cell_carcinoma	6364	26	16828	47	SLC4A4,SOX5,FGFRL1,EGF,SNTB1,GRK5,LRIG1,PTPRZ1,LPIN2,RFX4,AMOT,TNS3,GPC5,FGFR3,PRDM16,PREX1,LAMA4,FHOD3,PREX2,NFIA,NCKAP5,BCAR3,UNC93A,FARP1,ZBTB20,RORA
1.093e-02	-4.52	plasma membrane bounded cell projection morphogenesis	biological process	GO:0120039	491	5	18204	50	PREX2,PTN,PTPRZ1,SLC39A12,FARP1
1.094e-02	-4.52	positive regulation of hyaluronan biosynthetic process	biological process	GO:1900127	4	1	18204	50	EGF
1.094e-02	-4.52	positive regulation of phospholipid efflux	biological process	GO:1902995	4	1	18204	50	APOA1
1.094e-02	-4.52	negative regulation of glucokinase activity	biological process	GO:0033132	4	1	18204	50	PRKN
1.094e-02	-4.52	negative regulation of very-low-density lipoprotein particle remodeling	biological process	GO:0010903	4	1	18204	50	APOA1
1.094e-02	-4.52	parkin-mediated stimulation of mitophagy in response to mitochondrial depolarization	biological process	GO:0061734	4	1	18204	50	PRKN
1.094e-02	-4.52	regulation of phospholipid efflux	biological process	GO:1902994	4	1	18204	50	APOA1
1.094e-02	-4.52	positive regulation of mesenchymal stem cell differentiation	biological process	GO:2000741	4	1	18204	50	SOX5
1.094e-02	-4.52	positive regulation of mesodermal cell differentiation	biological process	GO:1905772	4	1	18204	50	GJA1
1.094e-02	-4.52	positive regulation of striated muscle tissue development	biological process	GO:0045844	4	1	18204	50	GJA1
1.094e-02	-4.52	positive regulation of muscle organ development	biological process	GO:0048636	4	1	18204	50	GJA1
1.094e-02	-4.52	negative regulation of hexokinase activity	biological process	GO:1903300	4	1	18204	50	PRKN
1.094e-02	-4.52	regulation of serotonin uptake	biological process	GO:0051611	4	1	18204	50	GPM6B
1.094e-02	-4.52	negative regulation of exosomal secretion	biological process	GO:1903542	4	1	18204	50	PRKN
1.094e-02	-4.52	gamma-aminobutyric acid reuptake	biological process	GO:0051936	4	1	18204	50	SLC6A11
1.095e-02	-4.51	import into cell	biological process	GO:0098657	687	6	18204	50	SLC6A11,CTBP1,PRKN,SLC39A12,SLC1A3,SLC1A2
1.099e-02	-4.51	QKI (QKI, KH domain containing RNA binding)	protein interactions	9444	183	3	19454	49	QKI,SLC39A12,MSI2
1.101e-02	-4.51	DHX33 (DEAH-box helicase 33)	protein interactions	56919	63	2	19454	49	FKBP5,PRKN
1.101e-02	-4.51	PLA2G4A (phospholipase A2 group IVA)	protein interactions	5321	63	2	19454	49	PRKN,FKBP5
1.106e-02	-4.50	(4Z,7Z,10Z,13Z,16Z)-docosa-4,7,10,13,16-pentaenoate biosynthesis (6-desaturase)	BIOCYC pathways	META_PWY-7726	5	1	902	2	ELOVL2
1.106e-02	-4.50	docosahexaenoate biosynthesis III (6-desaturase, mammals)	BIOCYC pathways	META_PWY-7606	5	1	902	2	ELOVL2
1.107e-02	-4.50	inorganic molecular entity transmembrane transporter activity	molecular function	GO:0015318	714	6	18094	48	SLC6A11,AQP4,SLC1A2,SLC39A12,SLC1A3,SLC4A4
1.107e-02	-4.50	transcription regulator activity	molecular function	GO:0140110	1937	11	18094	48	RFX4,PRKN,CTBP1,SOX5,RORA,TRPS1,PRDM16,NPAS3,ZBTB20,LPIN2,NFIA
1.110e-02	-4.50	cellular homeostasis	biological process	GO:0019725	689	6	18204	50	PRKN,ZBTB20,SLC4A4,AQP4,SLC1A3,SLC39A12
1.111e-02	-4.50	SLC3A2 (solute carrier family 3 member 2)	protein interactions	6520	346	4	19454	49	SLC1A2,GJA1,PRKN,PRDM16
1.113e-02	-4.50	SQSTM1 (sequestosome 1)	protein interactions	8878	984	7	19454	49	FHOD3,FGFR3,PRKN,AMOT,FARP1,GJA1,SNTB1
1.113e-02	-4.50	skin-benign_melanocytic_nevus-junctional	COSMIC cancer mutations	skin-benign_melanocytic_nevus-junctional	4	1	16828	47	FGFR3
1.113e-02	-4.50	skin-lower_leg-malignant_melanoma-nodular	COSMIC cancer mutations	skin-lower_leg-malignant_melanoma-nodular	4	1	16828	47	PREX2
1.113e-02	-4.50	inverted	COSMIC cancer mutations	inverted	4	1	16828	47	FGFR3
1.113e-02	-4.50	skin-face-malignant_melanoma-superficial_spreading	COSMIC cancer mutations	skin-face-malignant_melanoma-superficial_spreading	4	1	16828	47	PREX2
1.113e-02	-4.50	urinary_tract-bladder-other-normal	COSMIC cancer mutations	urinary_tract-bladder-other-normal	4	1	16828	47	FGFR3
1.113e-02	-4.50	urinary_tract-bladder-papilloma-inverted	COSMIC cancer mutations	urinary_tract-bladder-papilloma-inverted	4	1	16828	47	FGFR3
1.119e-02	-4.49	TPR_6	pfam domains	PF13174	4	1	17795	50	FKBP5
1.119e-02	-4.49	NHS	pfam domains	PF15273	4	1	17795	50	NHSL1
1.119e-02	-4.49	2-Hacid_dh	pfam domains	PF00389	4	1	17795	50	CTBP1
1.119e-02	-4.49	2-Hacid_dh_C	pfam domains	PF02826	4	1	17795	50	CTBP1
1.119e-02	-4.49	NfI_DNAbd_pre-N	pfam domains	PF10524	4	1	17795	50	NFIA
1.119e-02	-4.49	Apolipoprotein	pfam domains	PF01442	4	1	17795	50	APOA1
1.119e-02	-4.49	CTF_NFI	pfam domains	PF00859	4	1	17795	50	NFIA
1.119e-02	-4.49	PKD_4	pfam domains	PF18911	4	1	17795	50	SORCS2
1.120e-02	-4.49	cellular response to growth factor stimulus	biological process	GO:0071363	494	5	18204	50	NFIA,APOA1,FGFRL1,SOX5,FGFR3
1.120e-02	-4.49	tube development	biological process	GO:0035295	903	7	18204	50	NFIA,QKI,EGF,SLC39A12,GJA1,RORA,AMOT
1.123e-02	-4.49	Reuptake of GABA	REACTOME pathways	R-HSA-888593	4	1	10285	29	SLC6A11
1.123e-02	-4.49	PLCG1 events in ERBB2 signaling	REACTOME pathways	R-HSA-1251932	4	1	10285	29	EGF
1.125e-02	-4.49	bone-extraskeletal-Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour	COSMIC cancer mutations	bone-extraskeletal-Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour	891	7	16828	47	NPAS3,PTPRZ1,LRIG1,NCKAP5,FGFR3,SLC6A11,LAMA4
1.126e-02	-4.49	urinary_tract-bladder-carcinoma-transitional_cell_carcinoma	COSMIC cancer mutations	urinary_tract-bladder-carcinoma-transitional_cell_carcinoma	6040	25	16828	47	RFX4,LPIN2,PTPRZ1,GPC5,TNS3,SLC6A11,SLC1A3,FGFRL1,SLC4A4,GRK5,EGF,TRPS1,LRIG1,BCAR3,UNC93A,ZBTB20,FKBP5,FARP1,LAMA4,PRDM16,PREX1,ELOVL2,FGFR3,NFIA,PREX2
1.131e-02	-4.48	transitional_cell_carcinoma	COSMIC cancer mutations	transitional_cell_carcinoma	6042	25	16828	47	BCAR3,UNC93A,FARP1,ZBTB20,FKBP5,ELOVL2,FGFR3,LAMA4,PREX1,PRDM16,NFIA,PREX2,PTPRZ1,LPIN2,RFX4,SLC6A11,GPC5,TNS3,SLC1A3,SLC4A4,FGFRL1,EGF,GRK5,TRPS1,LRIG1
1.132e-02	-4.48	cognition	biological process	GO:0050890	319	4	18204	50	PRKN,ADGRB3,PTN,PTPRZ1
1.134e-02	-4.48	DGKE (diacylglycerol kinase epsilon)	protein interactions	8526	64	2	19454	49	DGKB,PRKN
1.134e-02	-4.48	VSX1 (visual system homeobox 1)	protein interactions	30813	64	2	19454	49	NFIA,TRPS1
1.136e-02	-4.48	upper_aerodigestive_tract-head_neck-carcinoma-squamous_cell_carcinoma	COSMIC cancer mutations	upper_aerodigestive_tract-head_neck-carcinoma-squamous_cell_carcinoma	9263	34	16828	47	FHOD3,NFIA,PREX2,ELOVL2,FGFR3,LAMA4,PREX1,PRDM16,UNC93A,NHSL1,FARP1,FKBP5,RORA,PTN,QKI,BCAR3,TRPS1,GPM6B,LRIG1,DGKB,SLC4A4,SOX5,SNTB1,EGF,GRK5,GPC5,TNS3,USP6NL,MSI2,SORCS2,PTPRZ1,CTBP1,AMOT,LPIN2
1.138e-02	-4.48	cell projection morphogenesis	biological process	GO:0048858	496	5	18204	50	FARP1,SLC39A12,PTPRZ1,PTN,PREX2
1.138e-02	-4.48	skin-scalp-carcinoma-squamous_cell_carcinoma	COSMIC cancer mutations	skin-scalp-carcinoma-squamous_cell_carcinoma	1596	10	16828	47	TRPS1,GPC5,FARP1,PTN,RORA,FGFR3,SLC4A4,PREX1,SOX5,PTPRZ1
1.140e-02	-4.47	neuron projection development	biological process	GO:0031175	693	6	18204	50	FARP1,GPM6B,PTN,PREX2,SLC39A12,PTPRZ1
1.143e-02	-4.47	human chr14q13.1	chromosome location	human chr14q13.1	6	1	26134	50	NPAS3
1.143e-02	-4.47	human chr1p32.2	chromosome location	human chr1p32.2	6	1	26134	50	PLPP3
1.170e-02	-4.45	positive regulation of phosphate metabolic process	biological process	GO:0045937	697	6	18204	50	SLC4A4,ZBTB20,PLPP3,FGFR3,EGF,BCAR3
1.170e-02	-4.45	positive regulation of phosphorus metabolic process	biological process	GO:0010562	697	6	18204	50	SLC4A4,PLPP3,EGF,FGFR3,ZBTB20,BCAR3
1.171e-02	-4.45	organic substance transport	biological process	GO:0071702	1881	11	18204	50	SLC1A3,SLC39A12,SORCS2,PRKN,SLC6A11,SLC4A4,APOA1,GJA1,GPM6B,SLC1A2,QKI
1.174e-02	-4.44	negative regulation of secretion	biological process	GO:0051048	172	3	18204	50	GJA1,PRKN,EGF
1.178e-02	-4.44	transmembrane receptor protein tyrosine kinase activity	molecular function	GO:0004714	62	2	18094	48	FGFRL1,FGFR3
1.181e-02	-4.44	Tyr_Pase_cat	interpro domains	IPR003595	61	2	18521	50	PTPRZ1,TNS3
1.181e-02	-4.44	C1-like_sf	interpro domains	IPR046349	61	2	18521	50	DGKB,TNS3
1.181e-02	-4.44	HNF1B (HNF1 homeobox B)	protein interactions	6928	188	3	19454	49	NFIA,TRPS1,SOX5
1.182e-02	-4.44	export across plasma membrane	biological process	GO:0140115	60	2	18204	50	SLC4A4,GJA1
1.192e-02	-4.43	chemical homeostasis	biological process	GO:0048878	914	7	18204	50	SLC39A12,SLC1A3,SLC4A4,AQP4,RORA,APOA1,ZBTB20
1.192e-02	-4.43	cartilage development	biological process	GO:0051216	173	3	18204	50	FGFR3,SOX5,NFIA
1.203e-02	-4.42	MAML1 (mastermind like transcriptional coactivator 1)	protein interactions	9794	66	2	19454	49	NFIA,CTBP1
1.203e-02	-4.42	DDX49 (DEAD-box helicase 49)	protein interactions	54555	66	2	19454	49	PRDM16,PRKN
1.205e-02	-4.42	extraskeletal	COSMIC cancer mutations	extraskeletal	903	7	16828	47	LRIG1,SLC6A11,NCKAP5,PTPRZ1,NPAS3,FGFR3,LAMA4
1.205e-02	-4.42	Phospholipase D signaling pathway	KEGG pathways	ko04072	145	3	7161	24	PLPP3,EGF,DGKB
1.205e-02	-4.42	Phospholipase D signaling pathway	KEGG pathways	hsa04072	145	3	7161	24	EGF,DGKB,PLPP3
1.215e-02	-4.41	CEP192 (centrosomal protein 192)	protein interactions	55125	190	3	19454	49	PRKN,FGFR3,AMOT
1.220e-02	-4.41	PH	smart domains	SM00233	259	4	9717	34	PREX1,FARP1,PREX2,SNTB1
1.220e-02	-4.41	bone mineralization	biological process	GO:0030282	61	2	18204	50	PTN,FGFR3
1.224e-02	-4.40	RBBP4 (RB binding protein 4, chromatin remodeling factor)	protein interactions	5928	551	5	19454	49	CTBP1,ZBTB20,PRKN,PRDM16,TRPS1
1.231e-02	-4.40	GRB2 (growth factor receptor bound protein 2)	protein interactions	2885	769	6	19454	49	MSI2,USP6NL,SLC1A2,PRKN,FGFR3,EGF
1.233e-02	-4.40	SON (SON DNA and RNA binding protein)	protein interactions	6651	191	3	19454	49	NFIA,PRDM16,PRKN
1.233e-02	-4.40	PFKL (phosphofructokinase, liver type)	protein interactions	5211	191	3	19454	49	PRKN,FGFR3,PRDM16
1.235e-02	-4.39	CXADR (CXADR Ig-like cell adhesion molecule)	protein interactions	1525	357	4	19454	49	GJA1,FARP1,USP6NL,AMOT
1.238e-02	-4.39	C15orf39 (chromosome 15 open reading frame 39)	protein interactions	56905	67	2	19454	49	CTBP1,PRKN
1.252e-02	-4.38	breast-carcinoma-ductolobular_carcinoma	COSMIC cancer mutations	breast-carcinoma-ductolobular_carcinoma	1619	10	16828	47	QKI,PTPRZ1,FGFR3,SLC39A12,LAMA4,FARP1,DGKB,RORA,FHOD3,PREX2
1.252e-02	-4.38	ductolobular_carcinoma	COSMIC cancer mutations	ductolobular_carcinoma	1619	10	16828	47	LAMA4,SLC39A12,FGFR3,QKI,PTPRZ1,PREX2,FHOD3,RORA,FARP1,DGKB
1.253e-02	-4.38	TRANK1 (tetratricopeptide repeat and ankyrin repeat containing 1)	protein interactions	9881	5	1	19454	49	PRKN
1.253e-02	-4.38	SCUBE3 (signal peptide, CUB domain and EGF like domain containing 3)	protein interactions	222663	5	1	19454	49	PRKN
1.253e-02	-4.38	TRPM6 (transient receptor potential cation channel subfamily M member 6)	protein interactions	140803	5	1	19454	49	PRKN
1.253e-02	-4.38	SIM1 (SIM bHLH transcription factor 1)	protein interactions	6492	5	1	19454	49	PRKN
1.253e-02	-4.38	SLIT3 (slit guidance ligand 3)	protein interactions	6586	5	1	19454	49	PRKN
1.253e-02	-4.38	RNF212 (ring finger protein 212)	protein interactions	285498	5	1	19454	49	PRKN
1.253e-02	-4.38	SLC25A36 (solute carrier family 25 member 36)	protein interactions	55186	5	1	19454	49	PTN
1.253e-02	-4.38	GCSAM (germinal center associated signaling and motility)	protein interactions	257144	5	1	19454	49	PRKN
1.253e-02	-4.38	CFAP251 (cilia and flagella associated protein 251)	protein interactions	144406	5	1	19454	49	PRKN
1.253e-02	-4.38	ATP8B3 (ATPase phospholipid transporting 8B3)	protein interactions	148229	5	1	19454	49	PRKN
1.253e-02	-4.38	PDE1A (phosphodiesterase 1A)	protein interactions	5136	5	1	19454	49	APOA1
1.253e-02	-4.38	CCDC152 (coiled-coil domain containing 152)	protein interactions	100129792	5	1	19454	49	PRKN
1.253e-02	-4.38	SPATA31A7 (SPATA31 subfamily A member 7)	protein interactions	26165	5	1	19454	49	GRK5
1.253e-02	-4.38	DENND2A (DENN domain containing 2A)	protein interactions	27147	5	1	19454	49	PRKN
1.253e-02	-4.38	RFX4 (regulatory factor X4)	protein interactions	5992	5	1	19454	49	RFX4
1.253e-02	-4.38	ANKRD20A4P (ankyrin repeat domain 20 family member A4, pseudogene)	protein interactions	728747	5	1	19454	49	PRKN
1.253e-02	-4.38	SPIC (Spi-C transcription factor)	protein interactions	121599	5	1	19454	49	PRKN
1.253e-02	-4.38	ANKRD30B (ankyrin repeat domain 30B)	protein interactions	374860	5	1	19454	49	PRKN
1.253e-02	-4.38	CCDC191 (coiled-coil domain containing 191)	protein interactions	57577	5	1	19454	49	PRKN
1.255e-02	-4.38	skin-extremity-malignant_melanoma	COSMIC cancer mutations	skin-extremity-malignant_melanoma	1875	11	16828	47	FHOD3,SLC6A11,PREX2,APOA1,USP6NL,FKBP5,PRDM16,SORCS2,CTBP1,PTPRZ1,BCAR3
1.259e-02	-4.38	regulation of substrate adhesion-dependent cell spreading	biological process	GO:1900024	62	2	18204	50	APOA1,PREX1
1.259e-02	-4.38	regulation of carbohydrate catabolic process	biological process	GO:0043470	62	2	18204	50	SLC4A4,ZBTB20
1.263e-02	-4.37	lower_leg	COSMIC cancer mutations	lower_leg	174	3	16828	47	FGFR3,SLC6A11,PREX2
1.268e-02	-4.37	UBE2J1 (ubiquitin conjugating enzyme E2 J1)	protein interactions	51465	193	3	19454	49	PRKN,GJA1,CTBP1
1.268e-02	-4.37	regulation of phosphate metabolic process	biological process	GO:0019220	1154	8	18204	50	BCAR3,PLPP3,EGF,FGFR3,APOA1,SLC4A4,PRKN,ZBTB20
1.270e-02	-4.37	CTBP1 (C-terminal binding protein 1)	protein interactions	1487	360	4	19454	49	PRDM16,TRPS1,PRKN,CTBP1
1.274e-02	-4.36	FOXP2 (forkhead box P2)	protein interactions	93986	68	2	19454	49	SOX5,CTBP1
1.274e-02	-4.36	MOB1A (MOB kinase activator 1A)	protein interactions	55233	68	2	19454	49	PRKN,AMOT
1.274e-02	-4.36	MARK1 (microtubule affinity regulating kinase 1)	protein interactions	4139	68	2	19454	49	SNTB1,GJA1
1.274e-02	-4.36	CTF_NFI_2	prosite domains	PS51080	4	1	12186	39	NFIA
1.274e-02	-4.36	D_2_HYDROXYACID_DH_3	prosite domains	PS00671	4	1	12186	39	CTBP1
1.274e-02	-4.36	CTF_NFI_1	prosite domains	PS00349	4	1	12186	39	NFIA
1.274e-02	-4.36	regulation of phosphorus metabolic process	biological process	GO:0051174	1155	8	18204	50	PRKN,ZBTB20,SLC4A4,APOA1,BCAR3,PLPP3,FGFR3,EGF
1.287e-02	-4.35	viral life cycle	biological process	GO:0019058	178	3	18204	50	CTBP1,USP6NL,NFIA
1.299e-02	-4.34	oesophagus-carcinoma-adenocarcinoma	COSMIC cancer mutations	oesophagus-carcinoma-adenocarcinoma	13112	43	16828	47	LRIG1,DGKB,TRPS1,GRK5,SNTB1,EGF,SOX5,FGFRL1,SLC4A4,SLC39A12,USP6NL,SLC1A3,GPC5,TNS3,SLC6A11,RFX4,LPIN2,AMOT,PTPRZ1,CTBP1,NPAS3,SORCS2,ASPA,PREX2,FHOD3,SLC1A2,LAMA4,PRDM16,PREX1,ELOVL2,FGFR3,FKBP5,ZBTB20,RORA,PTN,FARP1,NHSL1,UNC93A,GJA1,BCAR3,NCKAP5,QKI,AQP4
1.306e-02	-4.34	lipid homeostasis	biological process	GO:0055088	179	3	18204	50	APOA1,RORA,ZBTB20
1.308e-02	-4.34	skin-ear-carcinoma-squamous_cell_carcinoma	COSMIC cancer mutations	skin-ear-carcinoma-squamous_cell_carcinoma	506	5	16828	47	LAMA4,UNC93A,FGFR3,ZBTB20,NPAS3
1.309e-02	-4.34	upper_back	COSMIC cancer mutations	upper_back	328	4	16828	47	GPC5,FGFR3,FHOD3,SLC6A11
1.310e-02	-4.34	CTH (cystathionine gamma-lyase)	protein interactions	1491	69	2	19454	49	PRKN,CTBP1
1.310e-02	-4.34	FMNL2 (formin like 2)	protein interactions	114793	69	2	19454	49	GRK5,PRKN
1.317e-02	-4.33	carboxylic acid transmembrane transporter activity	molecular function	GO:0046943	186	3	18094	48	SLC1A3,SLC6A11,SLC1A2
1.320e-02	-4.33	glutathione transmembrane transporter activity	molecular function	GO:0034634	5	1	18094	48	GJA1
1.320e-02	-4.33	taurine transmembrane transporter activity	molecular function	GO:0005368	5	1	18094	48	SLC6A11
1.320e-02	-4.33	gap junction channel activity involved in cardiac conduction electrical coupling	molecular function	GO:0086075	5	1	18094	48	GJA1
1.321e-02	-4.33	primitive_neuroectodermal_tumour-medulloblastoma	COSMIC cancer mutations	primitive_neuroectodermal_tumour-medulloblastoma	15350	47	16828	47	GPC5,TNS3,USP6NL,SLC1A3,MSI2,LPIN2,RFX4,PTPRZ1,CTBP1,SLC39A12,GRK5,EGF,RORA,PTN,FARP1,BCAR3,NFIA,PREX2,PRDM16,SLC6A11,SORCS2,ASPA,AMOT,NPAS3,GPM6B,TRPS1,LRIG1,DGKB,FGFRL1,SOX5,SLC4A4,SNTB1,NHSL1,UNC93A,FKBP5,ZBTB20,AQP4,GJA1,NCKAP5,QKI,FHOD3,APOA1,LAMA4,PREX1,ELOVL2,FGFR3,SLC1A2
1.327e-02	-4.32	L-amino acid transmembrane transporter activity	molecular function	GO:0015179	66	2	18094	48	SLC1A3,SLC1A2
1.332e-02	-4.32	human chr8q13.2	chromosome location	human chr8q13.2	7	1	26134	50	PREX2
1.336e-02	-4.32	organic acid transmembrane transporter activity	molecular function	GO:0005342	187	3	18094	48	SLC1A2,SLC6A11,SLC1A3
1.338e-02	-4.31	PDZ	smart domains	SM00228	143	3	9717	34	PREX2,PREX1,SNTB1
1.343e-02	-4.31	BBP-like	interpro domains	IPR045071	5	1	18521	50	QKI
1.343e-02	-4.31	Laminin_dom_II	interpro domains	IPR010307	5	1	18521	50	LAMA4
1.343e-02	-4.31	Sortilin_C	interpro domains	IPR031777	5	1	18521	50	SORCS2
1.343e-02	-4.31	Na/HCO3_transpt	interpro domains	IPR003024	5	1	18521	50	SLC4A4
1.343e-02	-4.31	Syntrophin	interpro domains	IPR015482	5	1	18521	50	SNTB1
1.343e-02	-4.31	Sortilin_N	interpro domains	IPR031778	5	1	18521	50	SORCS2
1.343e-02	-4.31	VPS10	interpro domains	IPR006581	5	1	18521	50	SORCS2
1.343e-02	-4.31	Laminin_aI	interpro domains	IPR009254	5	1	18521	50	LAMA4
1.346e-02	-4.31	ITGB3 (integrin subunit beta 3)	protein interactions	3690	70	2	19454	49	PTN,PTPRZ1
1.346e-02	-4.31	TSHZ3 (teashirt zinc finger homeobox 3)	protein interactions	57616	70	2	19454	49	CTBP1,SOX5
1.346e-02	-4.31	PGAM2 (phosphoglycerate mutase 2)	protein interactions	5224	70	2	19454	49	SOX5,PLPP3
1.346e-02	-4.31	TMPPE (transmembrane protein with metallophosphoesterase domain)	protein interactions	643853	70	2	19454	49	PRKN,SLC39A12
1.348e-02	-4.31	-	gene3d domains	3.30.60.20	64	2	14470	40	TNS3,DGKB
1.353e-02	-4.30	monocarboxylic acid metabolic process	biological process	GO:0032787	518	5	18204	50	SLC1A3,ASPA,ELOVL2,QKI,LPIN2
1.354e-02	-4.30	transporter activity	molecular function	GO:0005215	1211	8	18094	48	SLC1A3,GJA1,SLC6A11,SLC1A2,SLC39A12,APOA1,SLC4A4,AQP4
1.357e-02	-4.30	TPX2 (TPX2 microtubule nucleation factor)	protein interactions	22974	198	3	19454	49	PREX1,FARP1,PRDM16
1.357e-02	-4.30	GSTP1 (glutathione S-transferase pi 1)	protein interactions	2950	198	3	19454	49	PTN,GJA1,PRKN
1.357e-02	-4.30	NDUFA7 (NADH:ubiquinone oxidoreductase subunit A7)	protein interactions	4701	198	3	19454	49	QKI,PRKN,GJA1
1.357e-02	-4.30	NFIX (nuclear factor I X)	protein interactions	4784	198	3	19454	49	TRPS1,NFIA,SOX5
1.365e-02	-4.29	sterol binding	molecular function	GO:0032934	67	2	18094	48	RORA,APOA1
1.366e-02	-4.29	retrograde trans-synaptic signaling	biological process	GO:0098917	5	1	18204	50	FARP1
1.366e-02	-4.29	otolith morphogenesis	biological process	GO:0032474	5	1	18204	50	LRIG1
1.366e-02	-4.29	regulation protein catabolic process at synapse	biological process	GO:0140250	5	1	18204	50	PRKN
1.366e-02	-4.29	regulation of synaptic vesicle transport	biological process	GO:1902803	5	1	18204	50	PRKN
1.366e-02	-4.29	regulation of glucokinase activity	biological process	GO:0033131	5	1	18204	50	PRKN
1.366e-02	-4.29	regulation of endosome organization	biological process	GO:1904978	5	1	18204	50	PRKN
1.366e-02	-4.29	head_neck	COSMIC cancer mutations	head_neck	15361	47	16828	47	PRDM16,NFIA,PREX2,BCAR3,RORA,PTN,FARP1,GRK5,EGF,SLC39A12,LPIN2,RFX4,PTPRZ1,CTBP1,MSI2,USP6NL,SLC1A3,GPC5,TNS3,SLC1A2,LAMA4,PREX1,ELOVL2,FGFR3,APOA1,FHOD3,GJA1,NCKAP5,QKI,AQP4,FKBP5,ZBTB20,NHSL1,UNC93A,SNTB1,FGFRL1,SOX5,SLC4A4,LRIG1,DGKB,GPM6B,TRPS1,AMOT,NPAS3,SORCS2,ASPA,SLC6A11
1.372e-02	-4.29	PE/DAG-bd	interpro domains	IPR002219	66	2	18521	50	TNS3,DGKB
1.375e-02	-4.29	-	gene3d domains	3.30.60.270	5	1	14470	40	SORCS2
1.375e-02	-4.29	Apolipoprotein	gene3d domains	1.20.120.20	5	1	14470	40	APOA1
1.375e-02	-4.29	-	gene3d domains	2.10.70.80	5	1	14470	40	SORCS2
1.376e-02	-4.29	WDR1 (WD repeat domain 1)	protein interactions	9948	199	3	19454	49	PRKN,CTBP1,MSI2
1.377e-02	-4.29	tissue regeneration	biological process	GO:0042246	65	2	18204	50	PTN,GJA1
1.383e-02	-4.28	UNKL (unk like zinc finger)	protein interactions	64718	71	2	19454	49	QKI,CTBP1
1.383e-02	-4.28	TRAPPC8 (trafficking protein particle complex subunit 8)	protein interactions	22878	71	2	19454	49	GJA1,PRKN
1.383e-02	-4.28	ABCB10 (ATP binding cassette subfamily B member 10)	protein interactions	23456	71	2	19454	49	SLC39A12,PRKN
1.384e-02	-4.28	regulation of cytoskeleton organization	biological process	GO:0051493	521	5	18204	50	GPM6B,SLC39A12,PREX1,PRKN,APOA1
1.384e-02	-4.28	muscle structure development	biological process	GO:0061061	521	5	18204	50	RORA,FGFRL1,QKI,FHOD3,ADGRB3
1.386e-02	-4.28	regulation of lipid localization	biological process	GO:1905952	183	3	18204	50	PRKN,EGF,APOA1
1.386e-02	-4.28	regulation of protein localization to membrane	biological process	GO:1905475	183	3	18204	50	GPC5,FARP1,PRKN
1.389e-02	-4.28	regulation of Wnt signaling pathway	biological process	GO:0030111	339	4	18204	50	GPC5,EGF,PLPP3,PRKN
1.389e-02	-4.28	CDC42 (cell division cycle 42)	protein interactions	998	1280	8	19454	49	ELOVL2,SLC1A3,PRKN,PREX2,FARP1,GJA1,PREX1,USP6NL
1.389e-02	-4.28	skin-shoulder-other-lichenoid_keratosis	COSMIC cancer mutations	skin-shoulder-other-lichenoid_keratosis	5	1	16828	47	FGFR3
1.389e-02	-4.28	skin-face-other-nevus_sebaceous	COSMIC cancer mutations	skin-face-other-nevus_sebaceous	5	1	16828	47	FGFR3
1.389e-02	-4.28	skin-forearm-other-lichenoid_keratosis	COSMIC cancer mutations	skin-forearm-other-lichenoid_keratosis	5	1	16828	47	FGFR3
1.389e-02	-4.28	skin-ear-other-nevus_sebaceous	COSMIC cancer mutations	skin-ear-other-nevus_sebaceous	5	1	16828	47	FGFR3
1.389e-02	-4.28	skin-neck-other-nevus_sebaceous	COSMIC cancer mutations	skin-neck-other-nevus_sebaceous	5	1	16828	47	FGFR3
1.389e-02	-4.28	skin-lower_leg-malignant_melanoma-superficial_spreading	COSMIC cancer mutations	skin-lower_leg-malignant_melanoma-superficial_spreading	5	1	16828	47	PREX2
1.389e-02	-4.28	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-monoclonal_gammopathy_of_undetermined_significance	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-monoclonal_gammopathy_of_undetermined_significance	5	1	16828	47	FGFR3
1.389e-02	-4.28	skin-adnexal_tumour-syringocystadenoma_papilliferum	COSMIC cancer mutations	skin-adnexal_tumour-syringocystadenoma_papilliferum	5	1	16828	47	FGFR3
1.389e-02	-4.28	skin-upper_arm-other-lichenoid_keratosis	COSMIC cancer mutations	skin-upper_arm-other-lichenoid_keratosis	5	1	16828	47	FGFR3
1.389e-02	-4.28	lichenoid_keratosis	COSMIC cancer mutations	lichenoid_keratosis	5	1	16828	47	FGFR3
1.389e-02	-4.28	skin-hand-other-lichenoid_keratosis	COSMIC cancer mutations	skin-hand-other-lichenoid_keratosis	5	1	16828	47	FGFR3
1.389e-02	-4.28	skin-shoulder-other-nevus_sebaceous	COSMIC cancer mutations	skin-shoulder-other-nevus_sebaceous	5	1	16828	47	FGFR3
1.389e-02	-4.28	skin-lower_leg-other-lichenoid_keratosis	COSMIC cancer mutations	skin-lower_leg-other-lichenoid_keratosis	5	1	16828	47	FGFR3
1.389e-02	-4.28	skin-face-other-lichenoid_keratosis	COSMIC cancer mutations	skin-face-other-lichenoid_keratosis	5	1	16828	47	FGFR3
1.389e-02	-4.28	syringocystadenoma_papilliferum	COSMIC cancer mutations	syringocystadenoma_papilliferum	5	1	16828	47	FGFR3
1.389e-02	-4.28	skin-other-lichenoid_keratosis	COSMIC cancer mutations	skin-other-lichenoid_keratosis	5	1	16828	47	FGFR3
1.389e-02	-4.28	skin-upper_back-other-lichenoid_keratosis	COSMIC cancer mutations	skin-upper_back-other-lichenoid_keratosis	5	1	16828	47	FGFR3
1.389e-02	-4.28	skin-breast-other-lichenoid_keratosis	COSMIC cancer mutations	skin-breast-other-lichenoid_keratosis	5	1	16828	47	FGFR3
1.389e-02	-4.28	monoclonal_gammopathy_of_undetermined_significance	COSMIC cancer mutations	monoclonal_gammopathy_of_undetermined_significance	5	1	16828	47	FGFR3
1.389e-02	-4.28	skin-chest-other-lichenoid_keratosis	COSMIC cancer mutations	skin-chest-other-lichenoid_keratosis	5	1	16828	47	FGFR3
1.389e-02	-4.28	skin-arm-other-seborrhoeic_keratosis	COSMIC cancer mutations	skin-arm-other-seborrhoeic_keratosis	5	1	16828	47	FGFR3
1.389e-02	-4.28	skin-forearm-other-seborrhoeic_keratosis	COSMIC cancer mutations	skin-forearm-other-seborrhoeic_keratosis	5	1	16828	47	FGFR3
1.389e-02	-4.28	skin-breast-other-nevus_sebaceous	COSMIC cancer mutations	skin-breast-other-nevus_sebaceous	5	1	16828	47	FGFR3
1.389e-02	-4.28	skin-scalp-other-nevus_sebaceous	COSMIC cancer mutations	skin-scalp-other-nevus_sebaceous	5	1	16828	47	FGFR3
1.389e-02	-4.28	skin-hip-other-seborrhoeic_keratosis	COSMIC cancer mutations	skin-hip-other-seborrhoeic_keratosis	5	1	16828	47	FGFR3
1.389e-02	-4.28	skin-neck-other-lichenoid_keratosis	COSMIC cancer mutations	skin-neck-other-lichenoid_keratosis	5	1	16828	47	FGFR3
1.389e-02	-4.28	skin-flank-other-lichenoid_keratosis	COSMIC cancer mutations	skin-flank-other-lichenoid_keratosis	5	1	16828	47	FGFR3
1.389e-02	-4.28	skin-upper_leg-other-lichenoid_keratosis	COSMIC cancer mutations	skin-upper_leg-other-lichenoid_keratosis	5	1	16828	47	FGFR3
1.389e-02	-4.28	skin-lower_back-other-nevus_sebaceous	COSMIC cancer mutations	skin-lower_back-other-nevus_sebaceous	5	1	16828	47	FGFR3
1.389e-02	-4.28	skin-lower_back-other-lichenoid_keratosis	COSMIC cancer mutations	skin-lower_back-other-lichenoid_keratosis	5	1	16828	47	FGFR3
1.392e-02	-4.27	extracellular matrix	cellular component	GO:0031012	559	5	19108	49	GPC5,APOA1,LRIG1,PTPRZ1,LAMA4
1.397e-02	-4.27	Laminin_II	pfam domains	PF06009	5	1	17795	50	LAMA4
1.397e-02	-4.27	Sortilin-Vps10	pfam domains	PF15902	5	1	17795	50	SORCS2
1.397e-02	-4.27	Laminin_I	pfam domains	PF06008	5	1	17795	50	LAMA4
1.397e-02	-4.27	Sortilin_C	pfam domains	PF15901	5	1	17795	50	SORCS2
1.402e-02	-4.27	external encapsulating structure	cellular component	GO:0030312	560	5	19108	49	GPC5,LRIG1,APOA1,PTPRZ1,LAMA4
1.402e-02	-4.27	MET interacts with TNS proteins	REACTOME pathways	R-HSA-8875513	5	1	10285	29	TNS3
1.402e-02	-4.27	Scavenging by Class B Receptors	REACTOME pathways	R-HSA-3000471	5	1	10285	29	APOA1
1.403e-02	-4.27	monoatomic ion transmembrane transporter activity	molecular function	GO:0015075	752	6	18094	48	SLC1A2,SLC39A12,GJA1,SLC6A11,SLC4A4,SLC1A3
1.403e-02	-4.27	central_nervous_system-brainstem-primitive_neuroectodermal_tumour-medulloblastoma-WNT_subtype	COSMIC cancer mutations	central_nervous_system-brainstem-primitive_neuroectodermal_tumour-medulloblastoma-WNT_subtype	181	3	16828	47	EGF,NPAS3,NCKAP5
1.408e-02	-4.26	regulation of hydrolase activity	biological process	GO:0051336	726	6	18204	50	FGFR3,BCAR3,APOA1,USP6NL,PREX1,PREX2
1.418e-02	-4.26	L-alpha-amino acid transmembrane transport	biological process	GO:1902475	66	2	18204	50	SLC1A2,SLC1A3
1.418e-02	-4.26	regulation of morphogenesis of an epithelium	biological process	GO:1905330	66	2	18204	50	GJA1,EGF
1.418e-02	-4.26	ERBB signaling pathway	biological process	GO:0038127	66	2	18204	50	EGF,BCAR3
1.420e-02	-4.25	GJA1 (gap junction protein alpha 1)	protein interactions	2697	572	5	19454	49	USP6NL,SLC39A12,APOA1,GJA1,FARP1
1.423e-02	-4.25	G protein-coupled receptor signaling pathway	biological process	GO:0007186	1178	8	18204	50	BCAR3,GRK5,ADGRB3,PREX2,SORCS2,PREX1,APOA1,DGKB
1.424e-02	-4.25	WNT_subtype	COSMIC cancer mutations	WNT_subtype	182	3	16828	47	EGF,NPAS3,NCKAP5
1.424e-02	-4.25	pancreas-carcinoma-adenocarcinoma	COSMIC cancer mutations	pancreas-carcinoma-adenocarcinoma	517	5	16828	47	SLC39A12,LAMA4,GPC5,PREX2,PRDM16
1.427e-02	-4.25	response to growth factor	biological process	GO:0070848	525	5	18204	50	SOX5,FGFR3,FGFRL1,APOA1,NFIA
1.430e-02	-4.25	regulation of actin cytoskeleton organization	biological process	GO:0032956	342	4	18204	50	PRKN,PREX1,APOA1,GPM6B
1.431e-02	-4.25	Constitutive Signaling by Aberrant PI3K in Cancer	REACTOME pathways	R-HSA-2219530	65	2	10285	29	EGF,FGFR3
1.432e-02	-4.25	FEV (FEV transcription factor, ETS family member)	protein interactions	54738	202	3	19454	49	NFIA,TRPS1,SOX5
1.433e-02	-4.25	oesophagus-carcinoma-squamous_cell_carcinoma	COSMIC cancer mutations	oesophagus-carcinoma-squamous_cell_carcinoma	6486	26	16828	47	AQP4,NCKAP5,UNC93A,FARP1,ZBTB20,FKBP5,FGFR3,LAMA4,PRDM16,PREX2,APOA1,SORCS2,PTPRZ1,NPAS3,AMOT,LPIN2,GPC5,TNS3,SLC4A4,SLC39A12,FGFRL1,SOX5,SNTB1,EGF,TRPS1,DGKB
1.445e-02	-4.24	Signal Transduction	REACTOME pathways	R-HSA-162582	2547	13	10285	29	CTBP1,GPC5,GRK5,FGFR3,FGFRL1,EGF,LRIG1,PREX1,LAMA4,AMOT,TNS3,DGKB,APOA1
1.448e-02	-4.23	kidney	COSMIC cancer mutations	kidney	15380	47	16828	47	SLC1A2,PREX1,LAMA4,FGFR3,ELOVL2,APOA1,FHOD3,GJA1,QKI,NCKAP5,AQP4,ZBTB20,FKBP5,NHSL1,UNC93A,SNTB1,SOX5,FGFRL1,SLC4A4,DGKB,LRIG1,GPM6B,TRPS1,AMOT,NPAS3,SORCS2,ASPA,SLC6A11,PRDM16,PREX2,NFIA,BCAR3,PTN,RORA,FARP1,GRK5,EGF,SLC39A12,RFX4,LPIN2,CTBP1,PTPRZ1,MSI2,SLC1A3,USP6NL,TNS3,GPC5
1.451e-02	-4.23	RBMS1 (RNA binding motif single stranded interacting protein 1)	protein interactions	5937	203	3	19454	49	QKI,MSI2,GRK5
1.455e-02	-4.23	Fosphenytoin (Antiarrhythmic) Metabolism Pathway	SMPDB pathways	SMP0000618	4	1	1369	5	SNTB1
1.458e-02	-4.23	KIAA0232 (KIAA0232)	protein interactions	9778	73	2	19454	49	FGFRL1,PRKN
1.458e-02	-4.23	KIF16B (kinesin family member 16B)	protein interactions	55614	73	2	19454	49	AMOT,GJA1
1.458e-02	-4.23	AGAP3 (ArfGAP with GTPase domain, ankyrin repeat and PH domain 3)	protein interactions	116988	73	2	19454	49	PRKN,NCKAP5
1.468e-02	-4.22	phosphate-containing compound metabolic process	biological process	GO:0006796	1681	10	18204	50	PLPP3,FGFR3,GRK5,PTPRZ1,CTBP1,DGKB,APOA1,ELOVL2,RORA,TNS3
1.469e-02	-4.22	inclusion body	cellular component	GO:0016234	72	2	19108	49	PRKN,PRDM16
1.470e-02	-4.22	NFIC (nuclear factor I C)	protein interactions	4782	204	3	19454	49	TRPS1,NFIA,SOX5
1.470e-02	-4.22	CASK (calcium/calmodulin dependent serine protein kinase)	protein interactions	8573	204	3	19454	49	GJA1,SNTB1,PRKN
1.472e-02	-4.22	chemotaxis	biological process	GO:0006935	345	4	18204	50	PTN,PREX1,AMOT,APOA1
1.474e-02	-4.22	ZF_DAG_PE_1	prosite domains	PS00479	58	2	12186	39	TNS3,DGKB
1.489e-02	-4.21	CTDP1 (CTD phosphatase subunit 1)	protein interactions	9150	205	3	19454	49	GRK5,PRKN,AMOT
1.495e-02	-4.20	PDGFRA (platelet derived growth factor receptor alpha)	protein interactions	5156	378	4	19454	49	LRIG1,FARP1,PRKN,FGFR3
1.496e-02	-4.20	ERCC6L (ERCC excision repair 6 like, spindle assembly checkpoint helicase)	protein interactions	54821	74	2	19454	49	AMOT,PRKN
1.496e-02	-4.20	DNAJC21 (DnaJ heat shock protein family (Hsp40) member C21)	protein interactions	134218	74	2	19454	49	FKBP5,PRKN
1.496e-02	-4.20	MORC3 (MORC family CW-type zinc finger 3)	protein interactions	23515	74	2	19454	49	SNTB1,PRKN
1.500e-02	-4.20	RAB5C (RAB5C, member RAS oncogene family)	protein interactions	5878	580	5	19454	49	ELOVL2,GJA1,PRKN,CTBP1,PLPP3
1.501e-02	-4.20	negative regulation of hormone secretion	biological process	GO:0046888	68	2	18204	50	GJA1,PRKN
1.501e-02	-4.20	regulation of tumor necrosis factor-mediated signaling pathway	biological process	GO:0010803	68	2	18204	50	APOA1,PRKN
1.501e-02	-4.20	taxis	biological process	GO:0042330	347	4	18204	50	PTN,PREX1,APOA1,AMOT
1.502e-02	-4.20	FGF23 (fibroblast growth factor 23)	protein interactions	8074	6	1	19454	49	FGFR3
1.502e-02	-4.20	CFHR1 (complement factor H related 1)	protein interactions	3078	6	1	19454	49	APOA1
1.502e-02	-4.20	SOX11 (SRY-box transcription factor 11)	protein interactions	6664	6	1	19454	49	SOX5
1.502e-02	-4.20	CCDC181 (coiled-coil domain containing 181)	protein interactions	57821	6	1	19454	49	PRKN
1.502e-02	-4.20	DAZ4 (deleted in azoospermia 4)	protein interactions	57135	6	1	19454	49	QKI
1.502e-02	-4.20	CA13 (carbonic anhydrase 13)	protein interactions	377677	6	1	19454	49	PRKN
1.502e-02	-4.20	TXNDC8 (thioredoxin domain containing 8)	protein interactions	255220	6	1	19454	49	PRKN
1.502e-02	-4.20	ABCA10 (ATP binding cassette subfamily A member 10)	protein interactions	10349	6	1	19454	49	PRKN
1.502e-02	-4.20	ARHGEF37 (Rho guanine nucleotide exchange factor 37)	protein interactions	389337	6	1	19454	49	PRKN
1.502e-02	-4.20	SIAH3 (siah E3 ubiquitin protein ligase family member 3)	protein interactions	283514	6	1	19454	49	PRKN
1.502e-02	-4.20	PBP2 (Pbp2p)	protein interactions	852533	6	1	19454	49	QKI
1.502e-02	-4.20	PKDREJ (polycystin family receptor for egg jelly)	protein interactions	10343	6	1	19454	49	PRKN
1.502e-02	-4.20	Map1b (microtubule-associated protein 1B)	protein interactions	17755	6	1	19454	49	PRKN
1.502e-02	-4.20	GARIN1B (golgi associated RAB2 interactor 1B)	protein interactions	84691	6	1	19454	49	PRKN
1.502e-02	-4.20	N6AMT1 (N-6 adenine-specific DNA methyltransferase 1)	protein interactions	29104	6	1	19454	49	PRKN
1.502e-02	-4.20	SAA4 (serum amyloid A4, constitutive)	protein interactions	6291	6	1	19454	49	GJA1
1.502e-02	-4.20	LCAT (lecithin-cholesterol acyltransferase)	protein interactions	3931	6	1	19454	49	APOA1
1.502e-02	-4.20	FGF18 (fibroblast growth factor 18)	protein interactions	8817	6	1	19454	49	FGFR3
1.502e-02	-4.20	SOX1 (SRY-box transcription factor 1)	protein interactions	6656	6	1	19454	49	SOX5
1.502e-02	-4.20	COL15A1 (collagen type XV alpha 1 chain)	protein interactions	1306	6	1	19454	49	PRKN
1.502e-02	-4.20	NEK5 (NIMA related kinase 5)	protein interactions	341676	6	1	19454	49	PRKN
1.502e-02	-4.20	FGF6 (fibroblast growth factor 6)	protein interactions	2251	6	1	19454	49	FGFR3
1.502e-02	-4.20	Csnk1d (casein kinase 1, delta)	protein interactions	64462	6	1	19454	49	PRKN
1.502e-02	-4.20	Map3k12 (mitogen-activated protein kinase kinase kinase 12)	protein interactions	26404	6	1	19454	49	USP6NL
1.508e-02	-4.19	PPFIA1 (PTPRF interacting protein alpha 1)	protein interactions	8500	206	3	19454	49	PRKN,GJA1,AMOT
1.521e-02	-4.19	human chr7p21.2	chromosome location	human chr7p21.2	8	1	26134	50	DGKB
1.524e-02	-4.18	upper_aerodigestive_tract	COSMIC cancer mutations	upper_aerodigestive_tract	13181	43	16828	47	BCAR3,NCKAP5,QKI,RORA,ZBTB20,FKBP5,PTN,FARP1,NHSL1,UNC93A,SLC1A2,LAMA4,PRDM16,PREX1,ELOVL2,FGFR3,APOA1,NFIA,PREX2,FHOD3,RFX4,LPIN2,AMOT,PTPRZ1,CTBP1,NPAS3,SORCS2,MSI2,USP6NL,SLC1A3,GPC5,TNS3,GRK5,SNTB1,EGF,FGFRL1,SOX5,SLC4A4,SLC39A12,LRIG1,DGKB,GPM6B,TRPS1
1.534e-02	-4.18	BCAS3 (BCAS3 microtubule associated cell migration factor)	protein interactions	54828	75	2	19454	49	CTBP1,PRKN
1.534e-02	-4.18	MICU1 (mitochondrial calcium uptake 1)	protein interactions	10367	75	2	19454	49	PRKN,SLC39A12
1.534e-02	-4.18	CLRN2 (clarin 2)	protein interactions	645104	75	2	19454	49	LRIG1,GJA1
1.535e-02	-4.18	GRWD1 (glutamate rich WD repeat containing 1)	protein interactions	83743	381	4	19454	49	FGFR3,GRK5,PRKN,LPIN2
1.535e-02	-4.18	phosphoric ester hydrolase activity	molecular function	GO:0042578	362	4	18094	48	PTPRZ1,PLPP3,LPIN2,TNS3
1.547e-02	-4.17	cell-cell contact zone	cellular component	GO:0044291	74	2	19108	49	GJA1,FGFRL1
1.547e-02	-4.17	PI4KA (phosphatidylinositol 4-kinase alpha)	protein interactions	5297	208	3	19454	49	GJA1,FGFR3,FKBP5
1.559e-02	-4.16	PH	pfam domains	PF00169	187	3	17795	50	PREX2,FARP1,SNTB1
1.573e-02	-4.15	PGM3 (phosphoglucomutase 3)	protein interactions	5238	76	2	19454	49	PRKN,TNS3
1.573e-02	-4.15	KIAA1549 (KIAA1549)	protein interactions	57670	76	2	19454	49	GJA1,AMOT
1.573e-02	-4.15	MIR200A (microRNA 200a)	protein interactions	406983	76	2	19454	49	QKI,MSI2
1.576e-02	-4.15	Spinal Cord Injury	WikiPathways	WP2431	119	3	5310	24	PTPRZ1,GJA1,AQP4
1.581e-02	-4.15	sodium:bicarbonate symporter activity	molecular function	GO:0008510	6	1	18094	48	SLC4A4
1.581e-02	-4.15	histone H3K9 monomethyltransferase activity	molecular function	GO:0140948	6	1	18094	48	PRDM16
1.581e-02	-4.15	phosphatidylcholine-sterol O-acyltransferase activator activity	molecular function	GO:0060228	6	1	18094	48	APOA1
1.581e-02	-4.15	gamma-aminobutyric acid:sodium:chloride symporter activity	molecular function	GO:0005332	6	1	18094	48	SLC6A11
1.581e-02	-4.15	gap junction hemi-channel activity	molecular function	GO:0055077	6	1	18094	48	GJA1
1.583e-02	-4.15	MARCKS (myristoylated alanine rich protein kinase C substrate)	protein interactions	4082	588	5	19454	49	USP6NL,PRKN,SLC1A3,ELOVL2,FARP1
1.587e-02	-4.14	TLE1 (TLE family member 1, transcriptional corepressor)	protein interactions	7088	210	3	19454	49	NFIA,PRKN,SOX5
1.587e-02	-4.14	ZNF326 (zinc finger protein 326)	protein interactions	284695	210	3	19454	49	NFIA,FGFR3,PRKN
1.607e-02	-4.13	CDK6 (cyclin dependent kinase 6)	protein interactions	1021	211	3	19454	49	FKBP5,SOX5,FGFR3
1.609e-02	-4.13	Glypican	interpro domains	IPR001863	6	1	18521	50	GPC5
1.609e-02	-4.13	Glypican_CS	interpro domains	IPR019803	6	1	18521	50	GPC5
1.609e-02	-4.13	ELO_CS	interpro domains	IPR030457	6	1	18521	50	ELOVL2
1.609e-02	-4.13	LNS2/PITP	interpro domains	IPR031315	6	1	18521	50	LPIN2
1.613e-02	-4.13	TNS3 (tensin 3)	protein interactions	64759	77	2	19454	49	APOA1,SNTB1
1.613e-02	-4.13	ADD2 (adducin 2)	protein interactions	119	77	2	19454	49	PRKN,PTPRZ1
1.613e-02	-4.13	PTPN5 (protein tyrosine phosphatase non-receptor type 5)	protein interactions	84867	77	2	19454	49	PRKN,APOA1
1.613e-02	-4.13	SDC1 (syndecan 1)	protein interactions	6382	77	2	19454	49	PTN,FARP1
1.622e-02	-4.12	phosphorus metabolic process	biological process	GO:0006793	1707	10	18204	50	PLPP3,FGFR3,GRK5,PTPRZ1,RORA,ELOVL2,APOA1,DGKB,CTBP1,TNS3
1.630e-02	-4.12	SMC1A (structural maintenance of chromosomes 1A)	protein interactions	8243	388	4	19454	49	FGFR3,PRKN,RORA,AMOT
1.637e-02	-4.11	regulation of synapse pruning	biological process	GO:1905806	6	1	18204	50	ADGRB3
1.637e-02	-4.11	regulation of spontaneous synaptic transmission	biological process	GO:0150003	6	1	18204	50	PRKN
1.637e-02	-4.11	negative regulation of neurotransmitter secretion	biological process	GO:0046929	6	1	18204	50	PRKN
1.637e-02	-4.11	asymmetric neuroblast division	biological process	GO:0055059	6	1	18204	50	SOX5
1.637e-02	-4.11	intracellular water homeostasis	biological process	GO:0009992	6	1	18204	50	AQP4
1.637e-02	-4.11	cell-cell adhesion mediated by integrin	biological process	GO:0033631	6	1	18204	50	PLPP3
1.637e-02	-4.11	positive regulation of neurotransmitter uptake	biological process	GO:0051582	6	1	18204	50	PRKN
1.637e-02	-4.11	dopamine uptake involved in synaptic transmission	biological process	GO:0051583	6	1	18204	50	PRKN
1.637e-02	-4.11	regulation of hexokinase activity	biological process	GO:1903299	6	1	18204	50	PRKN
1.637e-02	-4.11	gamma-aminobutyric acid biosynthetic process	biological process	GO:0009449	6	1	18204	50	SLC1A3
1.637e-02	-4.11	cell surface receptor protein tyrosine phosphatase signaling pathway	biological process	GO:0007185	6	1	18204	50	PTN
1.637e-02	-4.11	positive regulation of skeletal muscle acetylcholine-gated channel clustering	biological process	GO:1904395	6	1	18204	50	FARP1
1.637e-02	-4.11	aggresome assembly	biological process	GO:0070842	6	1	18204	50	PRKN
1.637e-02	-4.11	neuroblast migration	biological process	GO:0097402	6	1	18204	50	GJA1
1.637e-02	-4.11	amino acid neurotransmitter reuptake	biological process	GO:0051933	6	1	18204	50	SLC6A11
1.637e-02	-4.11	cholesterol import	biological process	GO:0070508	6	1	18204	50	APOA1
1.637e-02	-4.11	regulation of very-low-density lipoprotein particle remodeling	biological process	GO:0010901	6	1	18204	50	APOA1
1.637e-02	-4.11	positive regulation of cerebellar granule cell precursor proliferation	biological process	GO:0021940	6	1	18204	50	EGF
1.637e-02	-4.11	catecholamine uptake involved in synaptic transmission	biological process	GO:0051934	6	1	18204	50	PRKN
1.645e-02	-4.11	central_nervous_system-medulla-primitive_neuroectodermal_tumour-medulloblastoma-large_cell	COSMIC cancer mutations	central_nervous_system-medulla-primitive_neuroectodermal_tumour-medulloblastoma-large_cell	14773	46	16828	47	PREX1,LAMA4,FGFR3,ELOVL2,SLC1A2,FHOD3,APOA1,AQP4,GJA1,QKI,NHSL1,UNC93A,ZBTB20,FKBP5,SOX5,FGFRL1,SLC4A4,SNTB1,GPM6B,TRPS1,DGKB,LRIG1,SORCS2,ASPA,AMOT,NPAS3,SLC6A11,PRDM16,PREX2,NFIA,BCAR3,PTN,RORA,FARP1,SLC39A12,GRK5,EGF,MSI2,RFX4,LPIN2,CTBP1,PTPRZ1,TNS3,GPC5,SLC1A3,USP6NL
1.645e-02	-4.11	central_nervous_system-medulla-primitive_neuroectodermal_tumour-medulloblastoma-desmoplastic	COSMIC cancer mutations	central_nervous_system-medulla-primitive_neuroectodermal_tumour-medulloblastoma-desmoplastic	14773	46	16828	47	PREX1,LAMA4,FGFR3,ELOVL2,SLC1A2,FHOD3,APOA1,AQP4,GJA1,QKI,NHSL1,UNC93A,FKBP5,ZBTB20,SOX5,FGFRL1,SLC4A4,SNTB1,GPM6B,TRPS1,DGKB,LRIG1,SORCS2,ASPA,AMOT,NPAS3,SLC6A11,PRDM16,PREX2,NFIA,BCAR3,PTN,RORA,FARP1,SLC39A12,GRK5,EGF,MSI2,RFX4,LPIN2,CTBP1,PTPRZ1,TNS3,GPC5,SLC1A3,USP6NL
1.645e-02	-4.11	central_nervous_system-medulla-primitive_neuroectodermal_tumour-medulloblastoma	COSMIC cancer mutations	central_nervous_system-medulla-primitive_neuroectodermal_tumour-medulloblastoma	14773	46	16828	47	BCAR3,FARP1,PTN,RORA,PRDM16,PREX2,NFIA,CTBP1,PTPRZ1,LPIN2,RFX4,MSI2,SLC1A3,USP6NL,TNS3,GPC5,EGF,GRK5,SLC39A12,QKI,GJA1,AQP4,FKBP5,ZBTB20,UNC93A,NHSL1,SLC1A2,FGFR3,ELOVL2,PREX1,LAMA4,APOA1,FHOD3,NPAS3,AMOT,ASPA,SORCS2,SLC6A11,SNTB1,SLC4A4,FGFRL1,SOX5,DGKB,LRIG1,TRPS1,GPM6B
1.645e-02	-4.11	central_nervous_system-medulla-primitive_neuroectodermal_tumour-medulloblastoma-classic	COSMIC cancer mutations	central_nervous_system-medulla-primitive_neuroectodermal_tumour-medulloblastoma-classic	14773	46	16828	47	GPM6B,TRPS1,DGKB,LRIG1,FGFRL1,SOX5,SLC4A4,SNTB1,SLC6A11,SORCS2,ASPA,AMOT,NPAS3,FHOD3,APOA1,PREX1,LAMA4,FGFR3,ELOVL2,SLC1A2,NHSL1,UNC93A,ZBTB20,FKBP5,AQP4,GJA1,QKI,SLC39A12,GRK5,EGF,TNS3,GPC5,SLC1A3,USP6NL,MSI2,RFX4,LPIN2,CTBP1,PTPRZ1,PREX2,NFIA,PRDM16,PTN,RORA,FARP1,BCAR3
1.648e-02	-4.11	SEC24A (SEC24 homolog A, COPII coat complex component)	protein interactions	10802	213	3	19454	49	GJA1,FGFR3,PRKN
1.648e-02	-4.11	RPS6KA3 (ribosomal protein S6 kinase A3)	protein interactions	6197	213	3	19454	49	PRKN,FGFR3,CTBP1
1.648e-02	-4.11	COX5A (cytochrome c oxidase subunit 5A)	protein interactions	9377	213	3	19454	49	FKBP5,PRKN,PRDM16
1.649e-02	-4.11	homeostatic process	biological process	GO:0042592	1456	9	18204	50	PRKN,ZBTB20,AQP4,RORA,SLC4A4,APOA1,GJA1,SLC1A3,SLC39A12
1.649e-02	-4.11	classic	COSMIC cancer mutations	classic	14774	46	16828	47	APOA1,FHOD3,SLC1A2,ELOVL2,FGFR3,LAMA4,PREX1,ZBTB20,FKBP5,UNC93A,NHSL1,QKI,GJA1,AQP4,LRIG1,DGKB,TRPS1,GPM6B,SNTB1,SLC4A4,SOX5,FGFRL1,SLC6A11,NPAS3,AMOT,ASPA,SORCS2,NFIA,PREX2,PRDM16,FARP1,RORA,PTN,BCAR3,EGF,GRK5,SLC39A12,USP6NL,SLC1A3,GPC5,TNS3,PTPRZ1,CTBP1,LPIN2,RFX4,MSI2
1.652e-02	-4.10	ANKRD40 (ankyrin repeat domain 40)	protein interactions	91369	78	2	19454	49	SOX5,MSI2
1.652e-02	-4.10	SGK1 (serum/glucocorticoid regulated kinase 1)	protein interactions	6446	78	2	19454	49	SLC1A3,FKBP5
1.652e-02	-4.10	ALDH9A1 (aldehyde dehydrogenase 9 family member A1)	protein interactions	223	78	2	19454	49	FKBP5,PRKN
1.652e-02	-4.10	MIR34C (microRNA 34c)	protein interactions	407042	78	2	19454	49	MSI2,QKI
1.660e-02	-4.10	lower_third	COSMIC cancer mutations	lower_third	7961	30	16828	47	FKBP5,ZBTB20,RORA,FARP1,UNC93A,GJA1,NCKAP5,QKI,AQP4,APOA1,PREX2,FHOD3,PRDM16,PREX1,GPC5,TNS3,SLC6A11,LPIN2,PTPRZ1,NPAS3,SORCS2,ASPA,LRIG1,DGKB,GPM6B,TRPS1,SNTB1,SOX5,SLC39A12,SLC4A4
1.664e-02	-4.10	skin-face-other-seborrhoeic_keratosis	COSMIC cancer mutations	skin-face-other-seborrhoeic_keratosis	6	1	16828	47	FGFR3
1.664e-02	-4.10	skin-back-other-seborrhoeic_keratosis	COSMIC cancer mutations	skin-back-other-seborrhoeic_keratosis	6	1	16828	47	FGFR3
1.664e-02	-4.10	skin-abdomen-other-seborrhoeic_keratosis	COSMIC cancer mutations	skin-abdomen-other-seborrhoeic_keratosis	6	1	16828	47	FGFR3
1.664e-02	-4.10	skin-in_situ_epithelial_neoplasm-Bowen_disease	COSMIC cancer mutations	skin-in_situ_epithelial_neoplasm-Bowen_disease	6	1	16828	47	FGFR3
1.664e-02	-4.10	skin-arm-epidermal_nevus	COSMIC cancer mutations	skin-arm-epidermal_nevus	6	1	16828	47	FGFR3
1.664e-02	-4.10	autonomic_ganglia-paraganglioma-benign	COSMIC cancer mutations	autonomic_ganglia-paraganglioma-benign	6	1	16828	47	NHSL1
1.664e-02	-4.10	collecting_duct_carcinoma	COSMIC cancer mutations	collecting_duct_carcinoma	6	1	16828	47	FGFR3
1.664e-02	-4.10	skin-benign_melanocytic_nevus-lentiginous_nevus	COSMIC cancer mutations	skin-benign_melanocytic_nevus-lentiginous_nevus	6	1	16828	47	FGFR3
1.664e-02	-4.10	skin-forearm-malignant_melanoma-superficial_spreading	COSMIC cancer mutations	skin-forearm-malignant_melanoma-superficial_spreading	6	1	16828	47	PREX2
1.664e-02	-4.10	skin-epidermal_nevus	COSMIC cancer mutations	skin-epidermal_nevus	6	1	16828	47	FGFR3
1.664e-02	-4.10	skin-upper_leg-other-seborrhoeic_keratosis	COSMIC cancer mutations	skin-upper_leg-other-seborrhoeic_keratosis	6	1	16828	47	FGFR3
1.664e-02	-4.10	skin-trunk-epidermal_nevus	COSMIC cancer mutations	skin-trunk-epidermal_nevus	6	1	16828	47	FGFR3
1.664e-02	-4.10	skin-flank-other-seborrhoeic_keratosis	COSMIC cancer mutations	skin-flank-other-seborrhoeic_keratosis	6	1	16828	47	FGFR3
1.664e-02	-4.10	skin-in_situ_epithelial_neoplasm-actinic_keratosis	COSMIC cancer mutations	skin-in_situ_epithelial_neoplasm-actinic_keratosis	6	1	16828	47	FGFR3
1.664e-02	-4.10	skin-head_neck-epidermal_nevus	COSMIC cancer mutations	skin-head_neck-epidermal_nevus	6	1	16828	47	FGFR3
1.664e-02	-4.10	skin-lower_back-other-seborrhoeic_keratosis	COSMIC cancer mutations	skin-lower_back-other-seborrhoeic_keratosis	6	1	16828	47	FGFR3
1.664e-02	-4.10	skin-adnexal_tumour-trichoblastoma	COSMIC cancer mutations	skin-adnexal_tumour-trichoblastoma	6	1	16828	47	FGFR3
1.664e-02	-4.10	skin-head_neck-malignant_melanoma	COSMIC cancer mutations	skin-head_neck-malignant_melanoma	6	1	16828	47	PREX2
1.664e-02	-4.10	skin-lower_leg-epidermal_nevus	COSMIC cancer mutations	skin-lower_leg-epidermal_nevus	6	1	16828	47	FGFR3
1.664e-02	-4.10	kidney-carcinoma-collecting_duct_carcinoma	COSMIC cancer mutations	kidney-carcinoma-collecting_duct_carcinoma	6	1	16828	47	FGFR3
1.664e-02	-4.10	lentiginous_nevus	COSMIC cancer mutations	lentiginous_nevus	6	1	16828	47	FGFR3
1.667e-02	-4.09	medulla	COSMIC cancer mutations	medulla	14778	46	16828	47	BCAR3,RORA,PTN,FARP1,PRDM16,NFIA,PREX2,MSI2,RFX4,LPIN2,PTPRZ1,CTBP1,GPC5,TNS3,USP6NL,SLC1A3,SLC39A12,GRK5,EGF,AQP4,GJA1,QKI,NHSL1,UNC93A,ZBTB20,FKBP5,LAMA4,PREX1,ELOVL2,FGFR3,SLC1A2,FHOD3,APOA1,SORCS2,ASPA,AMOT,NPAS3,SLC6A11,SOX5,FGFRL1,SLC4A4,SNTB1,GPM6B,TRPS1,LRIG1,DGKB
1.668e-02	-4.09	transcription repressor complex	cellular component	GO:0017053	77	2	19108	49	CTBP1,PRDM16
1.668e-02	-4.09	DLG1 (discs large MAGUK scaffold protein 1)	protein interactions	1739	214	3	19454	49	AMOT,GJA1,PRKN
1.668e-02	-4.09	COPG1 (COPI coat complex subunit gamma 1)	protein interactions	22820	214	3	19454	49	GJA1,PRKN,FGFRL1
1.669e-02	-4.09	AKT1 (AKT serine/threonine kinase 1)	protein interactions	207	596	5	19454	49	GJA1,PREX1,PRKN,CTBP1,FKBP5
1.671e-02	-4.09	desmoplastic	COSMIC cancer mutations	desmoplastic	14779	46	16828	47	SLC39A12,GRK5,EGF,MSI2,RFX4,LPIN2,CTBP1,PTPRZ1,TNS3,GPC5,SLC1A3,USP6NL,PRDM16,PREX2,NFIA,BCAR3,PTN,RORA,FARP1,FGFRL1,SOX5,SLC4A4,SNTB1,GPM6B,TRPS1,DGKB,LRIG1,SORCS2,ASPA,AMOT,NPAS3,SLC6A11,PREX1,LAMA4,FGFR3,ELOVL2,SLC1A2,FHOD3,APOA1,AQP4,GJA1,QKI,NHSL1,UNC93A,FKBP5,ZBTB20
1.672e-02	-4.09	regulation of ATP metabolic process	biological process	GO:1903578	72	2	18204	50	ZBTB20,SLC4A4
1.674e-02	-4.09	Glypican	pfam domains	PF01153	6	1	17795	50	GPC5
1.679e-02	-4.09	femur	COSMIC cancer mutations	femur	1197	8	16828	47	GPC5,LRIG1,PREX1,SLC4A4,ELOVL2,PTPRZ1,NCKAP5,SNTB1
1.693e-02	-4.08	CDKN2D (cyclin dependent kinase inhibitor 2D)	protein interactions	1032	79	2	19454	49	QKI,CTBP1
1.693e-02	-4.08	ACTL6B (actin like 6B)	protein interactions	51412	79	2	19454	49	PRKN,CTBP1
1.693e-02	-4.08	GPR21 (G protein-coupled receptor 21)	protein interactions	2844	79	2	19454	49	GJA1,ELOVL2
1.693e-02	-4.08	PALS2 (protein associated with LIN7 2, MAGUK p55 family member)	protein interactions	51678	79	2	19454	49	TRPS1,PRKN
1.693e-02	-4.08	PRDM1 (PR/SET domain 1)	protein interactions	639	79	2	19454	49	NFIA,TRPS1
1.693e-02	-4.08	CANT1 (calcium activated nucleotidase 1)	protein interactions	124583	79	2	19454	49	LRIG1,GJA1
1.693e-02	-4.08	SLC39A12 (solute carrier family 39 member 12)	protein interactions	221074	79	2	19454	49	GJA1,QKI
1.693e-02	-4.08	DNAJB8 (DnaJ heat shock protein family (Hsp40) member B8)	protein interactions	165721	79	2	19454	49	ZBTB20,FKBP5
1.709e-02	-4.07	human chr2q21.2	chromosome location	human chr2q21.2	9	1	26134	50	NCKAP5
1.709e-02	-4.07	GABA-ergic synapse	cellular component	GO:0098982	78	2	19108	49	SLC6A11,CTBP1
1.710e-02	-4.07	ATP2B1 (ATPase plasma membrane Ca2+ transporting 1)	protein interactions	490	216	3	19454	49	GJA1,PRKN,FGFR3
1.710e-02	-4.07	MAGED2 (MAGE family member D2)	protein interactions	10916	216	3	19454	49	PRDM16,PRKN,FKBP5
1.711e-02	-4.07	NAHCO3TRSPRT	prints domains	PR01232	5	1	5227	18	SLC4A4
1.716e-02	-4.07	endothelial cell migration	biological process	GO:0043542	73	2	18204	50	AMOT,APOA1
1.716e-02	-4.07	vasculogenesis	biological process	GO:0001570	73	2	18204	50	AMOT,QKI
1.716e-02	-4.07	regulation of cartilage development	biological process	GO:0061035	73	2	18204	50	TRPS1,SOX5
1.721e-02	-4.06	leg	COSMIC cancer mutations	leg	969	7	16828	47	GRK5,EGF,PTPRZ1,FGFR3,SLC4A4,ZBTB20,SLC6A11
1.724e-02	-4.06	ZF_DAG_PE_2	prosite domains	PS50081	63	2	12186	39	TNS3,DGKB
1.731e-02	-4.06	SEC31A (SEC31 homolog A, COPII coat complex component)	protein interactions	22872	217	3	19454	49	CTBP1,GJA1,PRKN
1.733e-02	-4.06	PPP1CA (protein phosphatase 1 catalytic subunit alpha)	protein interactions	100009298	80	2	19454	49	FARP1,PREX2
1.733e-02	-4.06	QPCTL (glutaminyl-peptide cyclotransferase like)	protein interactions	54814	80	2	19454	49	PREX1,PRKN
1.733e-02	-4.06	DUSP3 (dual specificity phosphatase 3)	protein interactions	1845	80	2	19454	49	PRKN,EGF
1.733e-02	-4.06	GPRIN1 (G protein regulated inducer of neurite outgrowth 1)	protein interactions	114787	80	2	19454	49	FGFR3,GJA1
1.737e-02	-4.05	regulation of cellular process	biological process	GO:0050794	11468	39	18204	50	USP6NL,SLC4A4,CTBP1,RFX4,PTN,PREX2,FARP1,EGF,LPIN2,GPC5,SLC1A2,BCAR3,APOA1,GJA1,ZBTB20,MSI2,ASPA,SLC1A3,PTPRZ1,GPM6B,PRDM16,AMOT,DGKB,TRPS1,QKI,ADGRB3,NFIA,RORA,LAMA4,PREX1,PRKN,SOX5,SLC39A12,SORCS2,FGFRL1,NPAS3,PLPP3,FGFR3,GRK5
1.738e-02	-4.05	VPS10	smart domains	SM00602	5	1	9717	34	SORCS2
1.748e-02	-4.05	cell surface receptor signaling pathway	biological process	GO:0007166	1992	11	18204	50	APOA1,GRK5,FGFRL1,PLPP3,FGFR3,PTN,NFIA,BCAR3,FARP1,EGF,ADGRB3
1.750e-02	-4.05	GIN1 (gypsy retrotransposon integrase 1)	protein interactions	54826	7	1	19454	49	PRKN
1.750e-02	-4.05	ZBTB45 (zinc finger and BTB domain containing 45)	protein interactions	84878	7	1	19454	49	ZBTB20
1.750e-02	-4.05	Adrm1 (adhesion regulating molecule 1 26S proteasome ubiquitin receptor)	protein interactions	56436	7	1	19454	49	PRKN
1.750e-02	-4.05	TMC7 (transmembrane channel like 7)	protein interactions	79905	7	1	19454	49	PRKN
1.750e-02	-4.05	CETP (cholesteryl ester transfer protein)	protein interactions	1071	7	1	19454	49	APOA1
1.750e-02	-4.05	ANKRD36C (ankyrin repeat domain 36C)	protein interactions	400986	7	1	19454	49	PRKN
1.750e-02	-4.05	CAPN9 (calpain 9)	protein interactions	10753	7	1	19454	49	PRKN
1.750e-02	-4.05	ZFYVE28 (zinc finger FYVE-type containing 28)	protein interactions	57732	7	1	19454	49	EGF
1.750e-02	-4.05	RLIG1 (RNA 5'-phosphate and 3'-OH ligase 1)	protein interactions	91298	7	1	19454	49	PRKN
1.750e-02	-4.05	SLC16A5 (solute carrier family 16 member 5)	protein interactions	9121	7	1	19454	49	PTPRZ1
1.750e-02	-4.05	Pum2 (pumilio RNA-binding family member 2)	protein interactions	80913	7	1	19454	49	QKI
1.750e-02	-4.05	ABCC12 (ATP binding cassette subfamily C member 12)	protein interactions	94160	7	1	19454	49	NPAS3
1.750e-02	-4.05	PRAMEF5 (PRAME family member 5)	protein interactions	343068	7	1	19454	49	PRKN
1.750e-02	-4.05	NSUN7 (NOP2/Sun RNA methyltransferase family member 7)	protein interactions	79730	7	1	19454	49	PRKN
1.750e-02	-4.05	CDH10 (cadherin 10)	protein interactions	1008	7	1	19454	49	PTN
1.750e-02	-4.05	FAM186B (family with sequence similarity 186 member B)	protein interactions	84070	7	1	19454	49	PRKN
1.750e-02	-4.05	ZNF160 (zinc finger protein 160)	protein interactions	90338	7	1	19454	49	PRKN
1.750e-02	-4.05	ABCB11 (ATP binding cassette subfamily B member 11)	protein interactions	8647	7	1	19454	49	PRKN
1.750e-02	-4.05	SPAG17 (sperm associated antigen 17)	protein interactions	200162	7	1	19454	49	PRKN
1.750e-02	-4.05	HNRNPUL2-BSCL2 (HNRNPUL2-BSCL2 readthrough (NMD candidate))	protein interactions	100534595	7	1	19454	49	PRKN
1.750e-02	-4.05	C1QL3 (complement C1q like 3)	protein interactions	389941	7	1	19454	49	ADGRB3
1.750e-02	-4.05	RTL1 (retrotransposon Gag like 1)	protein interactions	388015	7	1	19454	49	PRKN
1.750e-02	-4.05	SAA2 (serum amyloid A2)	protein interactions	6289	7	1	19454	49	APOA1
1.750e-02	-4.05	LRRC18 (leucine rich repeat containing 18)	protein interactions	474354	7	1	19454	49	PRKN
1.752e-02	-4.04	GATAD2B (GATA zinc finger domain containing 2B)	protein interactions	57459	218	3	19454	49	PRKN,TRPS1,PRDM16
1.769e-02	-4.03	hepatocellular_carcinoma	COSMIC cancer mutations	hepatocellular_carcinoma	14800	46	16828	47	SLC1A2,PREX1,LAMA4,FGFR3,ELOVL2,APOA1,FHOD3,GJA1,QKI,NCKAP5,AQP4,ZBTB20,FKBP5,NHSL1,UNC93A,SNTB1,SOX5,FGFRL1,SLC4A4,DGKB,LRIG1,GPM6B,TRPS1,AMOT,NPAS3,SORCS2,ASPA,SLC6A11,PRDM16,PREX2,NFIA,BCAR3,PTN,RORA,FARP1,GRK5,EGF,SLC39A12,LPIN2,RFX4,CTBP1,PTPRZ1,SLC1A3,USP6NL,TNS3,GPC5
1.769e-02	-4.03	liver-carcinoma-hepatocellular_carcinoma	COSMIC cancer mutations	liver-carcinoma-hepatocellular_carcinoma	14800	46	16828	47	BCAR3,RORA,PTN,FARP1,PRDM16,NFIA,PREX2,LPIN2,RFX4,PTPRZ1,CTBP1,GPC5,TNS3,USP6NL,SLC1A3,SLC39A12,GRK5,EGF,AQP4,GJA1,NCKAP5,QKI,NHSL1,UNC93A,ZBTB20,FKBP5,LAMA4,PREX1,ELOVL2,FGFR3,SLC1A2,FHOD3,APOA1,SORCS2,ASPA,AMOT,NPAS3,SLC6A11,SOX5,FGFRL1,SLC4A4,SNTB1,GPM6B,TRPS1,LRIG1,DGKB
1.774e-02	-4.03	ARNT2 (aryl hydrocarbon receptor nuclear translocator 2)	protein interactions	9915	81	2	19454	49	NPAS3,CTBP1
1.774e-02	-4.03	SOX17 (SRY-box transcription factor 17)	protein interactions	64321	81	2	19454	49	NFIA,TRPS1
1.774e-02	-4.03	C11orf58 (chromosome 11 open reading frame 58)	protein interactions	10944	81	2	19454	49	PTN,PRKN
1.774e-02	-4.03	PPP2R5C (protein phosphatase 2 regulatory subunit B'gamma)	protein interactions	5527	81	2	19454	49	FKBP5,PRKN
1.774e-02	-4.03	FADS1 (fatty acid desaturase 1)	protein interactions	3992	81	2	19454	49	SLC39A12,PRKN
1.782e-02	-4.03	cerebellar climbing fiber to Purkinje cell synapse	cellular component	GO:0150053	7	1	19108	49	ADGRB3
1.794e-02	-4.02	MTREX (Mtr4 exosome RNA helicase)	protein interactions	23517	220	3	19454	49	PRDM16,GRK5,PRKN
1.799e-02	-4.02	cellular response to stimulus	biological process	GO:0051716	6307	25	18204	50	SLC1A3,APOA1,GJA1,ZBTB20,BCAR3,SLC1A2,FARP1,LPIN2,EGF,PREX2,PTN,AQP4,GRK5,FGFRL1,PLPP3,FGFR3,SORCS2,SLC39A12,RORA,PREX1,PRKN,NFIA,ADGRB3,DGKB,AMOT
1.803e-02	-4.02	SOX2 (SRY-box transcription factor 2)	protein interactions	6657	1342	8	19454	49	NFIA,TRPS1,APOA1,QKI,GJA1,CTBP1,MSI2,SOX5
1.806e-02	-4.01	regulation of DNA binding	biological process	GO:0051101	75	2	18204	50	EGF,PRKN
1.807e-02	-4.01	locomotion	biological process	GO:0040011	367	4	18204	50	PREX1,AMOT,APOA1,PTN
1.816e-02	-4.01	B4GALT1 (beta-1,4-galactosyltransferase 1)	protein interactions	2683	82	2	19454	49	CTBP1,SLC39A12
1.816e-02	-4.01	MADD (MAP kinase activating death domain)	protein interactions	8567	82	2	19454	49	GRK5,PRKN
1.816e-02	-4.01	RPS6KA1 (ribosomal protein S6 kinase A1)	protein interactions	6195	221	3	19454	49	PRKN,SNTB1,CTBP1
1.838e-02	-4.00	MRPL44 (mitochondrial ribosomal protein L44)	protein interactions	65080	222	3	19454	49	PTN,QKI,PRKN
1.838e-02	-4.00	PKP2 (plakophilin 2)	protein interactions	5318	222	3	19454	49	CTBP1,PRKN,GJA1
1.838e-02	-4.00	FGFR1 (fibroblast growth factor receptor 1)	protein interactions	2260	611	5	19454	49	FGFR3,SNTB1,NHSL1,FARP1,USP6NL
1.838e-02	-4.00	animal organ development	biological process	GO:0048513	2846	14	18204	50	PTN,RFX4,BCAR3,NFIA,SLC1A2,EGF,SOX5,APOA1,RORA,GJA1,FHOD3,LRIG1,FGFR3,FGFRL1
1.843e-02	-3.99	tripeptide transmembrane transporter activity	molecular function	GO:0042937	7	1	18094	48	GJA1
1.843e-02	-3.99	G protein-coupled receptor kinase activity	molecular function	GO:0004703	7	1	18094	48	GRK5
1.843e-02	-3.99	sphingosine-1-phosphate phosphatase activity	molecular function	GO:0042392	7	1	18094	48	PLPP3
1.843e-02	-3.99	histone H3K9me2 methyltransferase activity	molecular function	GO:0140947	7	1	18094	48	PRDM16
1.843e-02	-3.99	apolipoprotein receptor binding	molecular function	GO:0034190	7	1	18094	48	APOA1
1.843e-02	-3.99	fatty acid elongase activity	molecular function	GO:0009922	7	1	18094	48	ELOVL2
1.847e-02	-3.99	FBXO2 (F-box protein 2)	protein interactions	26232	403	4	19454	49	AMOT,LRIG1,LAMA4,FGFR3
1.852e-02	-3.99	actin-mediated cell contraction	biological process	GO:0070252	76	2	18204	50	QKI,GJA1
1.858e-02	-3.99	TUT4 (terminal uridylyl transferase 4)	protein interactions	23318	83	2	19454	49	FKBP5,PRKN
1.858e-02	-3.99	PAX2 (paired box 2)	protein interactions	5076	83	2	19454	49	TRPS1,NFIA
1.858e-02	-3.99	EPHB6 (EPH receptor B6)	protein interactions	2051	83	2	19454	49	FKBP5,USP6NL
1.858e-02	-3.99	DNM3 (dynamin 3)	protein interactions	26052	83	2	19454	49	PRKN,FGFR3
1.858e-02	-3.99	PPP2R5A (protein phosphatase 2 regulatory subunit B'alpha)	protein interactions	5525	83	2	19454	49	NHSL1,PRKN
1.859e-02	-3.98	UBE2A (ubiquitin conjugating enzyme E2 A)	protein interactions	7319	223	3	19454	49	PRKN,BCAR3,GJA1
1.875e-02	-3.98	Aquaporin_transptr	interpro domains	IPR034294	7	1	18521	50	AQP4
1.875e-02	-3.98	GPCR_kinase	interpro domains	IPR000239	7	1	18521	50	GRK5
1.875e-02	-3.98	ELO_fam	interpro domains	IPR002076	7	1	18521	50	ELOVL2
1.877e-02	-3.98	PSMD2 (proteasome 26S subunit ubiquitin receptor, non-ATPase 2)	protein interactions	5708	405	4	19454	49	GRK5,PRKN,GJA1,PTN
1.891e-02	-3.97	system process	biological process	GO:0003008	2015	11	18204	50	SLC1A2,ADGRB3,PTN,SNTB1,AQP4,SLC4A4,PTPRZ1,LRIG1,SLC1A3,PRKN,GJA1
1.893e-02	-3.97	lung-left_upper_lobe-carcinoma-adenocarcinoma	COSMIC cancer mutations	lung-left_upper_lobe-carcinoma-adenocarcinoma	556	5	16828	47	DGKB,PREX1,SLC4A4,SLC6A11,TRPS1
1.897e-02	-3.96	human chr10p12.33	chromosome location	human chr10p12.33	10	1	26134	50	SLC39A12
1.898e-02	-3.96	regulation of cholesterol transport	biological process	GO:0032374	77	2	18204	50	APOA1,EGF
1.898e-02	-3.96	regulation of sterol transport	biological process	GO:0032371	77	2	18204	50	EGF,APOA1
1.900e-02	-3.96	ELP2 (elongator acetyltransferase complex subunit 2)	protein interactions	55250	84	2	19454	49	FKBP5,PRKN
1.900e-02	-3.96	AMOTL1 (angiomotin like 1)	protein interactions	154810	84	2	19454	49	AMOT,PRKN
1.900e-02	-3.96	BCL2L11 (BCL2 like 11)	protein interactions	10018	84	2	19454	49	SLC39A12,PRKN
1.904e-02	-3.96	FOXC1 (forkhead box C1)	protein interactions	2296	225	3	19454	49	CTBP1,SOX5,NFIA
1.905e-02	-3.96	Diseases of signal transduction	REACTOME pathways	R-HSA-5663202	369	4	10285	29	FGFR3,CTBP1,QKI,EGF
1.905e-02	-3.96	ELO	prosite domains	PS01188	6	1	12186	39	ELOVL2
1.905e-02	-3.96	GLYPICAN	prosite domains	PS01207	6	1	12186	39	GPC5
1.906e-02	-3.96	central_nervous_system-brain-glioma	COSMIC cancer mutations	central_nervous_system-brain-glioma	15470	47	16828	47	SNTB1,SLC4A4,SOX5,FGFRL1,DGKB,LRIG1,TRPS1,GPM6B,NPAS3,AMOT,ASPA,SORCS2,SLC6A11,SLC1A2,FGFR3,ELOVL2,PREX1,LAMA4,APOA1,FHOD3,QKI,NCKAP5,GJA1,AQP4,ZBTB20,FKBP5,UNC93A,NHSL1,EGF,GRK5,SLC39A12,CTBP1,PTPRZ1,LPIN2,RFX4,MSI2,SLC1A3,USP6NL,TNS3,GPC5,PRDM16,PREX2,NFIA,BCAR3,FARP1,PTN,RORA
1.907e-02	-3.96	regulation of skeletal muscle acetylcholine-gated channel clustering	biological process	GO:1904393	7	1	18204	50	FARP1
1.907e-02	-3.96	fatty acid elongation, unsaturated fatty acid	biological process	GO:0019368	7	1	18204	50	ELOVL2
1.907e-02	-3.96	glutathione transmembrane transport	biological process	GO:0034775	7	1	18204	50	GJA1
1.907e-02	-3.96	regulation of retrograde transport, endosome to Golgi	biological process	GO:1905279	7	1	18204	50	PRKN
1.907e-02	-3.96	inclusion body assembly	biological process	GO:0070841	7	1	18204	50	PRKN
1.907e-02	-3.96	free ubiquitin chain polymerization	biological process	GO:0010994	7	1	18204	50	PRKN
1.907e-02	-3.96	fatty acid elongation, monounsaturated fatty acid	biological process	GO:0034625	7	1	18204	50	ELOVL2
1.907e-02	-3.96	trans-synaptic signaling by trans-synaptic complex	biological process	GO:0099545	7	1	18204	50	FARP1
1.907e-02	-3.96	regulation of oligodendrocyte progenitor proliferation	biological process	GO:0070445	7	1	18204	50	PTPRZ1
1.907e-02	-3.96	regulation of 3'-UTR-mediated mRNA stabilization	biological process	GO:1905868	7	1	18204	50	QKI
1.907e-02	-3.96	glial cell fate specification	biological process	GO:0021780	7	1	18204	50	NFIA
1.907e-02	-3.96	high-density lipoprotein particle clearance	biological process	GO:0034384	7	1	18204	50	APOA1
1.907e-02	-3.96	fatty acid elongation, polyunsaturated fatty acid	biological process	GO:0034626	7	1	18204	50	ELOVL2
1.912e-02	-3.96	PTPc_motif	smart domains	SM00404	61	2	9717	34	PTPRZ1,TNS3
1.920e-02	-3.95	left_upper_lobe	COSMIC cancer mutations	left_upper_lobe	558	5	16828	47	DGKB,PREX1,SLC4A4,SLC6A11,TRPS1
1.923e-02	-3.95	ESYT1 (extended synaptotagmin 1)	protein interactions	23344	408	4	19454	49	GPM6B,PRKN,GJA1,ELOVL2
1.926e-02	-3.95	TGM2 (transglutaminase 2)	protein interactions	7052	226	3	19454	49	GJA1,PREX1,PRKN
1.930e-02	-3.95	WH_DNA-bd_sf	interpro domains	IPR036390	211	3	18521	50	PREX1,PREX2,RFX4
1.939e-02	-3.94	SEC16A (SEC16 homolog A, endoplasmic reticulum export factor)	protein interactions	9919	409	4	19454	49	TRPS1,PRKN,GJA1,AMOT
1.939e-02	-3.94	urinary_tract-carcinoma-transitional_cell_carcinoma	COSMIC cancer mutations	urinary_tract-carcinoma-transitional_cell_carcinoma	7	1	16828	47	FGFR3
1.939e-02	-3.94	skin-face-adnexal_tumour-malignant_adnexal_tumour	COSMIC cancer mutations	skin-face-adnexal_tumour-malignant_adnexal_tumour	7	1	16828	47	FGFR3
1.939e-02	-3.94	skin-chest-other-seborrhoeic_keratosis	COSMIC cancer mutations	skin-chest-other-seborrhoeic_keratosis	7	1	16828	47	FGFR3
1.939e-02	-3.94	skin-face-malignant_melanoma-nodular	COSMIC cancer mutations	skin-face-malignant_melanoma-nodular	7	1	16828	47	PREX2
1.939e-02	-3.94	trichilemmoma	COSMIC cancer mutations	trichilemmoma	7	1	16828	47	FGFR3
1.939e-02	-3.94	nevus_sebaceous	COSMIC cancer mutations	nevus_sebaceous	7	1	16828	47	FGFR3
1.939e-02	-3.94	skin-benign_melanocytic_nevus-compound	COSMIC cancer mutations	skin-benign_melanocytic_nevus-compound	7	1	16828	47	FGFR3
1.939e-02	-3.94	skin-upper_leg-malignant_melanoma-nodular	COSMIC cancer mutations	skin-upper_leg-malignant_melanoma-nodular	7	1	16828	47	PREX2
1.939e-02	-3.94	skin-benign_melanocytic_nevus-intradermal	COSMIC cancer mutations	skin-benign_melanocytic_nevus-intradermal	7	1	16828	47	FGFR3
1.939e-02	-3.94	skin-other-nevus_sebaceous	COSMIC cancer mutations	skin-other-nevus_sebaceous	7	1	16828	47	FGFR3
1.939e-02	-3.94	skin-adnexal_tumour-trichilemmoma	COSMIC cancer mutations	skin-adnexal_tumour-trichilemmoma	7	1	16828	47	FGFR3
1.939e-02	-3.94	skin-shoulder-other-seborrhoeic_keratosis	COSMIC cancer mutations	skin-shoulder-other-seborrhoeic_keratosis	7	1	16828	47	FGFR3
1.939e-02	-3.94	skin-neck-other-seborrhoeic_keratosis	COSMIC cancer mutations	skin-neck-other-seborrhoeic_keratosis	7	1	16828	47	FGFR3
1.943e-02	-3.94	CCND3 (cyclin D3)	protein interactions	896	85	2	19454	49	PRKN,QKI
1.943e-02	-3.94	ABHD12 (abhydrolase domain containing 12, lysophospholipase)	protein interactions	26090	85	2	19454	49	SLC39A12,PRKN
1.943e-02	-3.94	DDX19A (DEAD-box helicase 19A)	protein interactions	55308	85	2	19454	49	FGFR3,PRKN
1.943e-02	-3.94	CFAP298 (cilia and flagella associated protein 298)	protein interactions	56683	85	2	19454	49	FKBP5,TRPS1
1.944e-02	-3.94	inorganic cation transmembrane transporter activity	molecular function	GO:0022890	589	5	18094	48	SLC4A4,SLC1A3,SLC6A11,SLC1A2,SLC39A12
1.948e-02	-3.94	FOXK1 (forkhead box K1)	protein interactions	221937	227	3	19454	49	SOX5,AMOT,CTBP1
1.948e-02	-3.94	ARMC8 (armadillo repeat containing 8)	protein interactions	25852	227	3	19454	49	MSI2,NCKAP5,PRKN
1.951e-02	-3.94	ELO	pfam domains	PF01151	7	1	17795	50	ELOVL2
1.954e-02	-3.94	transmembrane receptor protein kinase activity	molecular function	GO:0019199	81	2	18094	48	FGFRL1,FGFR3
1.958e-02	-3.93	FGFR3b ligand binding and activation	REACTOME pathways	R-HSA-190371	7	1	10285	29	FGFR3
1.971e-02	-3.93	CSK (C-terminal Src kinase)	protein interactions	1445	854	6	19454	49	USP6NL,PTPRZ1,AMOT,TNS3,GJA1,PRKN
1.973e-02	-3.93	regulation of neurogenesis	biological process	GO:0050767	377	4	18204	50	QKI,PTPRZ1,PTN,ASPA
1.982e-02	-3.92	CDC37 (cell division cycle 37, HSP90 cochaperone)	protein interactions	11140	623	5	19454	49	FARP1,PRKN,GRK5,FGFR3,FKBP5
1.986e-02	-3.92	DNPEP (aspartyl aminopeptidase)	protein interactions	23549	86	2	19454	49	TNS3,PRKN
1.986e-02	-3.92	EGLN1 (egl-9 family hypoxia inducible factor 1)	protein interactions	54583	86	2	19454	49	FGFR3,FKBP5
1.986e-02	-3.92	LIN54 (lin-54 DREAM MuvB core complex component)	protein interactions	132660	86	2	19454	49	SOX5,PRKN
1.998e-02	-3.91	DENND10P1 (DENND10 pseudogene 1)	protein interactions	55855	8	1	19454	49	PRKN
1.998e-02	-3.91	DEFB104A (defensin beta 104A)	protein interactions	140596	8	1	19454	49	GJA1
1.998e-02	-3.91	AMDHD2 (amidohydrolase domain containing 2)	protein interactions	51005	8	1	19454	49	PRKN
1.998e-02	-3.91	CNMD (chondromodulin)	protein interactions	11061	8	1	19454	49	APOA1
1.998e-02	-3.91	ASPA (aspartoacylase)	protein interactions	443	8	1	19454	49	ASPA
1.998e-02	-3.91	MARCHF10 (membrane associated ring-CH-type finger 10)	protein interactions	162333	8	1	19454	49	CTBP1
1.998e-02	-3.91	Prkca (protein kinase C, alpha)	protein interactions	24680	8	1	19454	49	PRKN
1.998e-02	-3.91	GRIK4 (glutamate ionotropic receptor kainate type subunit 4)	protein interactions	2900	8	1	19454	49	PRKN
1.998e-02	-3.91	CCDC30 (coiled-coil domain containing 30)	protein interactions	728621	8	1	19454	49	PRKN
1.998e-02	-3.91	IGKV2-30 (immunoglobulin kappa variable 2-30)	protein interactions	28919	8	1	19454	49	PRKN
1.998e-02	-3.91	HSD11B2 (hydroxysteroid 11-beta dehydrogenase 2)	protein interactions	3291	8	1	19454	49	CTBP1
1.998e-02	-3.91	ARHGAP28 (Rho GTPase activating protein 28)	protein interactions	79822	8	1	19454	49	PRKN
1.998e-02	-3.91	HSD3B1 (hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1)	protein interactions	3283	8	1	19454	49	PRKN
1.998e-02	-3.91	GLYAT (glycine-N-acyltransferase)	protein interactions	10249	8	1	19454	49	PTN
1.998e-02	-3.91	DENND6B (DENN domain containing 6B)	protein interactions	414918	8	1	19454	49	PRKN
1.998e-02	-3.91	PDE6B (phosphodiesterase 6B)	protein interactions	5158	8	1	19454	49	CTBP1
1.998e-02	-3.91	DEPP1 (DEPP autophagy regulator 1)	protein interactions	11067	8	1	19454	49	QKI
1.998e-02	-3.91	HHIP (hedgehog interacting protein)	protein interactions	64399	8	1	19454	49	PRKN
1.998e-02	-3.91	BPI (bactericidal permeability increasing protein)	protein interactions	671	8	1	19454	49	PRKN
2.000e-02	-3.91	oesophagus-lower_third-carcinoma-adenocarcinoma	COSMIC cancer mutations	oesophagus-lower_third-carcinoma-adenocarcinoma	6302	25	16828	47	DGKB,TRPS1,GPM6B,SNTB1,SLC39A12,SOX5,SLC6A11,GPC5,NPAS3,PTPRZ1,LPIN2,ASPA,SORCS2,APOA1,FHOD3,PREX2,PREX1,FARP1,RORA,FKBP5,ZBTB20,QKI,NCKAP5,GJA1,AQP4
2.006e-02	-3.91	intracellular signal transduction	biological process	GO:0035556	1505	9	18204	50	BCAR3,FARP1,EGF,FGFR3,PREX2,AMOT,APOA1,DGKB,PREX1
2.029e-02	-3.90	ADPGK (ADP dependent glucokinase)	protein interactions	83440	87	2	19454	49	PRKN,SLC39A12
2.029e-02	-3.90	CSTF2T (cleavage stimulation factor subunit 2 tau variant)	protein interactions	23283	87	2	19454	49	PRKN,SORCS2
2.029e-02	-3.90	MIR141 (microRNA 141)	protein interactions	406933	87	2	19454	49	QKI,MSI2
2.029e-02	-3.90	Kctd5 (potassium channel tetramerisation domain containing 5)	protein interactions	69259	87	2	19454	49	TRPS1,SLC1A3
2.029e-02	-3.90	ZNF608 (zinc finger protein 608)	protein interactions	57507	87	2	19454	49	NFIA,SOX5
2.029e-02	-3.90	NHLH1 (nescient helix-loop-helix 1)	protein interactions	4807	87	2	19454	49	TRPS1,NFIA
2.029e-02	-3.90	FANCC (FA complementation group C)	protein interactions	2176	87	2	19454	49	PRKN,CTBP1
2.034e-02	-3.90	Lewy body	cellular component	GO:0097413	8	1	19108	49	PRKN
2.034e-02	-3.90	extrinsic component of postsynaptic membrane	cellular component	GO:0098890	8	1	19108	49	FARP1
2.034e-02	-3.90	spherical high-density lipoprotein particle	cellular component	GO:0034366	8	1	19108	49	APOA1
2.044e-02	-3.89	RHOJ (ras homolog family member J)	protein interactions	57381	628	5	19454	49	USP6NL,GJA1,FARP1,SLC1A3,SNTB1
2.049e-02	-3.89	EGFTGF	prints domains	PR00009	6	1	5227	18	EGF
2.062e-02	-3.88	CTNND1 (catenin delta 1)	protein interactions	1500	232	3	19454	49	GJA1,PRKN,PLPP3
2.062e-02	-3.88	PRKAA2 (protein kinase AMP-activated catalytic subunit alpha 2)	protein interactions	5563	232	3	19454	49	AMOT,PRKN,SLC4A4
2.073e-02	-3.88	FGA (fibrinogen alpha chain)	protein interactions	2243	88	2	19454	49	APOA1,GJA1
2.073e-02	-3.88	TMEM128 (transmembrane protein 128)	protein interactions	85013	88	2	19454	49	GJA1,SLC1A3
2.074e-02	-3.88	bone-fibula-Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour	COSMIC cancer mutations	bone-fibula-Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour	377	4	16828	47	NCKAP5,GRK5,FGFR3,SORCS2
2.082e-02	-3.87	LNS2	smart domains	SM00775	6	1	9717	34	LPIN2
2.086e-02	-3.87	SEC23IP (SEC23 interacting protein)	protein interactions	11196	233	3	19454	49	CTBP1,GJA1,PRKN
2.087e-02	-3.87	adult locomotory behavior	biological process	GO:0008344	81	2	18204	50	PREX2,PRKN
2.094e-02	-3.87	protein stabilization	biological process	GO:0050821	214	3	18204	50	APOA1,PRKN,PLPP3
2.095e-02	-3.87	regulation of actin filament-based process	biological process	GO:0032970	384	4	18204	50	GPM6B,APOA1,PRKN,PREX1
2.103e-02	-3.86	glutamate binding	molecular function	GO:0016595	8	1	18094	48	SLC1A3
2.103e-02	-3.86	gap junction channel activity involved in cell communication by electrical coupling	molecular function	GO:1903763	8	1	18094	48	GJA1
2.105e-02	-3.86	glutamatergic synapse	cellular component	GO:0098978	412	4	19108	49	SLC1A2,FARP1,CTBP1,ADGRB3
2.109e-02	-3.86	SEC24B (SEC24 homolog B, COPII coat complex component)	protein interactions	10427	234	3	19454	49	FGFR3,PRKN,GJA1
2.109e-02	-3.86	HMG20A (high mobility group 20A)	protein interactions	10363	234	3	19454	49	SOX5,NFIA,SNTB1
2.117e-02	-3.86	intracellular chemical homeostasis	biological process	GO:0055082	581	5	18204	50	ZBTB20,SLC4A4,AQP4,SLC1A3,SLC39A12
2.117e-02	-3.85	SOX10 (SRY-box transcription factor 10)	protein interactions	6663	89	2	19454	49	NFIA,TRPS1
2.117e-02	-3.85	KNSTRN (kinetochore localized astrin (SPAG5) binding protein)	protein interactions	90417	89	2	19454	49	NCKAP5,PRKN
2.119e-02	-3.85	Alpha-synuclein signaling	Pathway Interaction DB	alphasynuclein_pathway	32	2	2226	16	PRKN,GRK5
2.120e-02	-3.85	dephosphorylation	biological process	GO:0016311	215	3	18204	50	PTPRZ1,TNS3,PLPP3
2.127e-02	-3.85	positive regulation of metabolic process	biological process	GO:0009893	3796	17	18204	50	NPAS3,PLPP3,FGFR3,PRDM16,RORA,APOA1,GJA1,PRKN,ZBTB20,QKI,EGF,LPIN2,BCAR3,NFIA,SLC4A4,CTBP1,RFX4
2.133e-02	-3.85	MARK3 (microtubule affinity regulating kinase 3)	protein interactions	4140	235	3	19454	49	GJA1,SNTB1,PRKN
2.135e-02	-3.85	lens development in camera-type eye	biological process	GO:0002088	82	2	18204	50	GJA1,BCAR3
2.140e-02	-3.84	PTB	interpro domains	IPR013625	8	1	18521	50	TNS3
2.140e-02	-3.84	RFX-like	interpro domains	IPR039779	8	1	18521	50	RFX4
2.140e-02	-3.84	Tensin_C2-dom	interpro domains	IPR014020	8	1	18521	50	TNS3
2.140e-02	-3.84	PKD/Chitinase_dom	interpro domains	IPR022409	8	1	18521	50	SORCS2
2.140e-02	-3.84	Tensin_phosphatase	interpro domains	IPR029023	8	1	18521	50	TNS3
2.140e-02	-3.84	DAD_dom	interpro domains	IPR014767	8	1	18521	50	FHOD3
2.151e-02	-3.84	forearm	COSMIC cancer mutations	forearm	81	2	16828	47	PREX2,FGFR3
2.154e-02	-3.84	C1	smart domains	SM00109	65	2	9717	34	DGKB,TNS3
2.155e-02	-3.84	central_nervous_system-brain-atypical_teratoid-rhabdoid_tumour	COSMIC cancer mutations	central_nervous_system-brain-atypical_teratoid-rhabdoid_tumour	213	3	16828	47	FGFR3,PREX1,NCKAP5
2.155e-02	-3.84	atypical_teratoid-rhabdoid_tumour	COSMIC cancer mutations	atypical_teratoid-rhabdoid_tumour	213	3	16828	47	PREX1,FGFR3,NCKAP5
2.162e-02	-3.83	BRAP (BRCA1 associated protein)	protein interactions	8315	90	2	19454	49	APOA1,PRKN
2.162e-02	-3.83	PRTN3 (proteinase 3)	protein interactions	5657	90	2	19454	49	CTBP1,FGFR3
2.167e-02	-3.83	regulation of supramolecular fiber organization	biological process	GO:1902903	388	4	18204	50	APOA1,PRKN,PREX1,SLC39A12
2.172e-02	-3.83	positive regulation of cellular catabolic process	biological process	GO:0031331	217	3	18204	50	ZBTB20,PRKN,SLC4A4
2.172e-02	-3.83	regulation of cell junction assembly	biological process	GO:1901888	217	3	18204	50	ADGRB3,FARP1,GPM6B
2.177e-02	-3.83	regulation of epithelial tube formation	biological process	GO:1905276	8	1	18204	50	EGF
2.177e-02	-3.83	motor learning	biological process	GO:0061743	8	1	18204	50	ADGRB3
2.177e-02	-3.83	regulation of ventricular cardiac muscle cell membrane depolarization	biological process	GO:0060373	8	1	18204	50	GJA1
2.177e-02	-3.83	taurine transmembrane transport	biological process	GO:0015734	8	1	18204	50	SLC6A11
2.177e-02	-3.83	aspartate metabolic process	biological process	GO:0006531	8	1	18204	50	ASPA
2.177e-02	-3.83	positive regulation of mitophagy in response to mitochondrial depolarization	biological process	GO:0098779	8	1	18204	50	PRKN
2.177e-02	-3.83	ERBB2-EGFR signaling pathway	biological process	GO:0038134	8	1	18204	50	EGF
2.177e-02	-3.83	negative regulation of mitochondrial fusion	biological process	GO:0010637	8	1	18204	50	PRKN
2.177e-02	-3.83	leukocyte chemotaxis involved in inflammatory response	biological process	GO:0002232	8	1	18204	50	PTN
2.177e-02	-3.83	alkanesulfonate transmembrane transport	biological process	GO:0042918	8	1	18204	50	SLC6A11
2.177e-02	-3.83	negative regulation of gonadotropin secretion	biological process	GO:0032277	8	1	18204	50	GJA1
2.177e-02	-3.83	gamma-aminobutyric acid metabolic process	biological process	GO:0009448	8	1	18204	50	SLC1A3
2.177e-02	-3.83	plasma membrane to endosome transport	biological process	GO:0048227	8	1	18204	50	USP6NL
2.177e-02	-3.83	fatty acid elongation, saturated fatty acid	biological process	GO:0019367	8	1	18204	50	ELOVL2
2.177e-02	-3.83	negative regulation of trophoblast cell migration	biological process	GO:1901164	8	1	18204	50	GJA1
2.177e-02	-3.83	regulation of Cdc42 protein signal transduction	biological process	GO:0032489	8	1	18204	50	APOA1
2.177e-02	-3.83	positive regulation of epithelial tube formation	biological process	GO:1905278	8	1	18204	50	EGF
2.177e-02	-3.83	gap junction assembly	biological process	GO:0016264	8	1	18204	50	GJA1
2.177e-02	-3.83	regulation of hyaluronan biosynthetic process	biological process	GO:1900125	8	1	18204	50	EGF
2.177e-02	-3.83	positive regulation of CoA-transferase activity	biological process	GO:1905920	8	1	18204	50	APOA1
2.177e-02	-3.83	tachykinin receptor signaling pathway	biological process	GO:0007217	8	1	18204	50	GRK5
2.180e-02	-3.83	CREB1 (cAMP responsive element binding protein 1)	protein interactions	1385	237	3	19454	49	NFIA,BCAR3,PRKN
2.186e-02	-3.82	PDZ domain binding	molecular function	GO:0030165	86	2	18094	48	SNTB1,PRKN
2.191e-02	-3.82	-	gene3d domains	2.20.25.20	8	1	14470	40	PRKN
2.191e-02	-3.82	-	gene3d domains	2.60.40.1110	8	1	14470	40	TNS3
2.204e-02	-3.81	CDC16 (cell division cycle 16)	protein interactions	8881	238	3	19454	49	FHOD3,TRPS1,PRKN
2.207e-02	-3.81	TRMT6 (tRNA methyltransferase 6 non-catalytic subunit)	protein interactions	51605	91	2	19454	49	PRKN,FKBP5
2.207e-02	-3.81	MICU2 (mitochondrial calcium uptake 2)	protein interactions	221154	91	2	19454	49	PRKN,SLC39A12
2.207e-02	-3.81	TRAPPC12 (trafficking protein particle complex subunit 12)	protein interactions	51112	91	2	19454	49	PRKN,CTBP1
2.207e-02	-3.81	TRIO (trio Rho guanine nucleotide exchange factor)	protein interactions	7204	91	2	19454	49	PRDM16,GJA1
2.207e-02	-3.81	FOXI1 (forkhead box I1)	protein interactions	2299	91	2	19454	49	TRPS1,NFIA
2.207e-02	-3.81	NEIL3 (nei like DNA glycosylase 3)	protein interactions	55247	91	2	19454	49	FKBP5,QKI
2.213e-02	-3.81	junctional	COSMIC cancer mutations	junctional	8	1	16828	47	FGFR3
2.213e-02	-3.81	trichoblastoma	COSMIC cancer mutations	trichoblastoma	8	1	16828	47	FGFR3
2.213e-02	-3.81	skin-chest-malignant_melanoma-nodular	COSMIC cancer mutations	skin-chest-malignant_melanoma-nodular	8	1	16828	47	PREX2
2.213e-02	-3.81	cervical_intraepithelial_neoplasia_Grade_I	COSMIC cancer mutations	cervical_intraepithelial_neoplasia_Grade_I	8	1	16828	47	FGFR3
2.213e-02	-3.81	actinic_keratosis	COSMIC cancer mutations	actinic_keratosis	8	1	16828	47	FGFR3
2.213e-02	-3.81	urinary_tract-ureter-carcinoma-transitional_cell_carcinoma	COSMIC cancer mutations	urinary_tract-ureter-carcinoma-transitional_cell_carcinoma	8	1	16828	47	FGFR3
2.213e-02	-3.81	cervix-in_situ_neoplasm-cervical_intraepithelial_neoplasia_Grade_I	COSMIC cancer mutations	cervix-in_situ_neoplasm-cervical_intraepithelial_neoplasia_Grade_I	8	1	16828	47	FGFR3
2.213e-02	-3.81	central_nervous_system-chiasm-glioma-astrocytoma_Grade_I	COSMIC cancer mutations	central_nervous_system-chiasm-glioma-astrocytoma_Grade_I	8	1	16828	47	QKI
2.216e-02	-3.81	monoatomic ion transmembrane transport	biological process	GO:0034220	804	6	18204	50	SLC6A11,SLC4A4,GJA1,SLC1A2,SLC1A3,SLC39A12
2.216e-02	-3.81	embryonic morphogenesis	biological process	GO:0048598	588	5	18204	50	SLC39A12,LRIG1,PLPP3,GJA1,AMOT
2.218e-02	-3.81	Triglyceride Biosynthesis	REACTOME pathways	R-HSA-75109	82	2	10285	29	ELOVL2,LPIN2
2.226e-02	-3.80	PTEN_C2	pfam domains	PF10409	8	1	17795	50	TNS3
2.226e-02	-3.80	PTB	pfam domains	PF08416	8	1	17795	50	TNS3
2.233e-02	-3.80	L-amino acid transport	biological process	GO:0015807	84	2	18204	50	SLC1A2,SLC1A3
2.233e-02	-3.80	regulation of stem cell differentiation	biological process	GO:2000736	84	2	18204	50	PTN,SOX5
2.234e-02	-3.80	Release of Hh-Np from the secreting cell	REACTOME pathways	R-HSA-5362798	8	1	10285	29	GPC5
2.239e-02	-3.80	spindle	COSMIC cancer mutations	spindle	386	4	16828	47	GRK5,FGFRL1,PREX2,FGFR3
2.245e-02	-3.80	GUSBP1 (GUSB pseudogene 1)	protein interactions	728411	9	1	19454	49	FGFR3
2.245e-02	-3.80	KLB (klotho beta)	protein interactions	152831	9	1	19454	49	FGFR3
2.245e-02	-3.80	PABPC1L2A (poly(A) binding protein cytoplasmic 1 like 2A)	protein interactions	340529	9	1	19454	49	PRKN
2.245e-02	-3.80	Ywhag (tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide)	protein interactions	22628	9	1	19454	49	QKI
2.245e-02	-3.80	SOBP (sine oculis binding protein homolog)	protein interactions	55084	9	1	19454	49	CTBP1
2.245e-02	-3.80	ABI3BP (ABI family member 3 binding protein)	protein interactions	25890	9	1	19454	49	GRK5
2.245e-02	-3.80	MMP28 (matrix metallopeptidase 28)	protein interactions	79148	9	1	19454	49	PRKN
2.245e-02	-3.80	AMY2B (amylase alpha 2B)	protein interactions	280	9	1	19454	49	PRKN
2.245e-02	-3.80	CASS4 (Cas scaffold protein family member 4)	protein interactions	57091	9	1	19454	49	PRKN
2.245e-02	-3.80	Prmt5 (protein arginine N-methyltransferase 5)	protein interactions	27374	9	1	19454	49	FARP1
2.245e-02	-3.80	KCNV2 (potassium voltage-gated channel modifier subfamily V member 2)	protein interactions	169522	9	1	19454	49	PRKN
2.245e-02	-3.80	DNAH11 (dynein axonemal heavy chain 11)	protein interactions	8701	9	1	19454	49	PRKN
2.245e-02	-3.80	SLC16A6 (solute carrier family 16 member 6)	protein interactions	9120	9	1	19454	49	PRKN
2.245e-02	-3.80	Kif18a (kinesin family member 18A)	protein interactions	228421	9	1	19454	49	CTBP1
2.245e-02	-3.80	MYOM3 (myomesin 3)	protein interactions	127294	9	1	19454	49	AMOT
2.245e-02	-3.80	ABCA6 (ATP binding cassette subfamily A member 6)	protein interactions	23460	9	1	19454	49	APOA1
2.250e-02	-3.79	regulation of peptidyl-tyrosine phosphorylation	biological process	GO:0050730	220	3	18204	50	EGF,FGFR3,PLPP3
2.253e-02	-3.79	ACBD3 (acyl-CoA binding domain containing 3)	protein interactions	64746	240	3	19454	49	PRKN,FGFR3,GJA1
2.253e-02	-3.79	LIMS1 (LIM zinc finger domain containing 1)	protein interactions	3987	92	2	19454	49	FKBP5,PRKN
2.253e-02	-3.79	LEMD2 (LEM domain nuclear envelope protein 2)	protein interactions	221496	92	2	19454	49	SLC39A12,PRKN
2.253e-02	-3.79	FNTA (farnesyltransferase, CAAX box, subunit alpha)	protein interactions	2339	92	2	19454	49	PRKN,FGFR3
2.253e-02	-3.79	ZHX1 (zinc fingers and homeoboxes 1)	protein interactions	11244	92	2	19454	49	LAMA4,SOX5
2.253e-02	-3.79	ADGRG5 (adhesion G protein-coupled receptor G5)	protein interactions	221188	92	2	19454	49	GJA1,GPM6B
2.253e-02	-3.79	DPF1 (double PHD fingers 1)	protein interactions	8193	92	2	19454	49	PRKN,NFIA
2.253e-02	-3.79	SOX9 (SRY-box transcription factor 9)	protein interactions	6662	92	2	19454	49	TRPS1,NFIA
2.258e-02	-3.79	fibula	COSMIC cancer mutations	fibula	387	4	16828	47	SORCS2,FGFR3,GRK5,NCKAP5
2.260e-02	-3.79	Tyr_Pase_dom	interpro domains	IPR000387	86	2	18521	50	PTPRZ1,TNS3
2.261e-02	-3.79	Transmission across Chemical Synapses	REACTOME pathways	R-HSA-112315	217	3	10285	29	SLC6A11,SLC1A2,SLC1A3
2.261e-02	-3.79	nodular	COSMIC cancer mutations	nodular	1515	9	16828	47	PREX2,SLC6A11,FKBP5,SLC4A4,FGFR3,GRK5,PTPRZ1,NPAS3,EGF
2.274e-02	-3.78	lipid biosynthetic process	biological process	GO:0008610	592	5	18204	50	LPIN2,QKI,DGKB,APOA1,ELOVL2
2.277e-02	-3.78	regulation of cell-substrate adhesion	biological process	GO:0010810	221	3	18204	50	GPM6B,PREX1,APOA1
2.283e-02	-3.78	chondrocyte differentiation	biological process	GO:0002062	85	2	18204	50	SOX5,FGFR3
2.285e-02	-3.78	astrocyte end-foot	cellular component	GO:0097450	9	1	19108	49	AQP4
2.285e-02	-3.78	fascia adherens	cellular component	GO:0005916	9	1	19108	49	GJA1
2.299e-02	-3.77	MPDZ (multiple PDZ domain crumbs cell polarity complex component)	protein interactions	8777	93	2	19454	49	AMOT,FGFR3
2.299e-02	-3.77	MIR19B2 (microRNA 19b-2)	protein interactions	406981	93	2	19454	49	QKI,MSI2
2.299e-02	-3.77	FKBP15 (FKBP prolyl isomerase family member 15)	protein interactions	23307	93	2	19454	49	PRKN,AMOT
2.299e-02	-3.77	PTPRG (protein tyrosine phosphatase receptor type G)	protein interactions	5793	93	2	19454	49	FARP1,GJA1
2.299e-02	-3.77	TEX11 (testis expressed 11)	protein interactions	56159	93	2	19454	49	QKI,SOX5
2.299e-02	-3.77	UTP25 (UTP25 small subunit processome component)	protein interactions	27042	93	2	19454	49	PRKN,PREX1
2.299e-02	-3.77	RBM23 (RNA binding motif protein 23)	protein interactions	55147	93	2	19454	49	QKI,PTN
2.299e-02	-3.77	ODR4 (odr-4 GPCR localization factor homolog)	protein interactions	54953	93	2	19454	49	LRIG1,PRKN
2.302e-02	-3.77	peritoneum-appendix-other-pseudomyxoma_peritonei	COSMIC cancer mutations	peritoneum-appendix-other-pseudomyxoma_peritonei	585	5	16828	47	NCKAP5,FARP1,TRPS1,FGFR3,TNS3
2.302e-02	-3.77	pseudomyxoma_peritonei	COSMIC cancer mutations	pseudomyxoma_peritonei	585	5	16828	47	NCKAP5,FARP1,TRPS1,FGFR3,TNS3
2.304e-02	-3.77	MAPK cascade	biological process	GO:0000165	222	3	18204	50	EGF,FGFR3,APOA1
2.317e-02	-3.76	appendix	COSMIC cancer mutations	appendix	586	5	16828	47	TRPS1,FGFR3,TNS3,NCKAP5,FARP1
2.324e-02	-3.76	Bile secretion	KEGG pathways	ko04976	71	2	7161	24	SLC4A4,AQP4
2.324e-02	-3.76	Bile secretion	KEGG pathways	hsa04976	71	2	7161	24	SLC4A4,AQP4
2.331e-02	-3.76	glycerolipid biosynthetic process	biological process	GO:0045017	223	3	18204	50	LPIN2,APOA1,DGKB
2.332e-02	-3.76	uveal_tract	COSMIC cancer mutations	uveal_tract	587	5	16828	47	GRK5,FGFRL1,PREX1,PREX2,FGFR3
2.332e-02	-3.76	peritoneum	COSMIC cancer mutations	peritoneum	587	5	16828	47	FARP1,NCKAP5,FGFR3,TRPS1,TNS3
2.345e-02	-3.75	GRIN1 (glutamate ionotropic receptor NMDA type subunit 1)	protein interactions	2902	94	2	19454	49	FGFR3,PRKN
2.345e-02	-3.75	NANS (N-acetylneuraminate synthase)	protein interactions	54187	94	2	19454	49	PRKN,FKBP5
2.345e-02	-3.75	TRAPPC11 (trafficking protein particle complex subunit 11)	protein interactions	60684	94	2	19454	49	CTBP1,PRKN
2.345e-02	-3.75	QSER1 (glutamine and serine rich 1)	protein interactions	79832	94	2	19454	49	SOX5,NFIA
2.345e-02	-3.75	FOXP4 (forkhead box P4)	protein interactions	116113	94	2	19454	49	NFIA,SOX5
2.345e-02	-3.75	Wnt Signaling Pathway Netpath	WikiPathways	WP363	53	2	5310	24	CTBP1,GJA1
2.363e-02	-3.75	gamma-aminobutyric acid transmembrane transporter activity	molecular function	GO:0015185	9	1	18094	48	SLC6A11
2.363e-02	-3.75	chondroitin sulfate binding	molecular function	GO:0035374	9	1	18094	48	PTN
2.376e-02	-3.74	SCRIB (scribble planar cell polarity protein)	protein interactions	23513	245	3	19454	49	LRIG1,GJA1,PRKN
2.377e-02	-3.74	Internalization of ErbB1	Pathway Interaction DB	erbb1_internalization_pathway	34	2	2226	16	LRIG1,EGF
2.381e-02	-3.74	collagen-containing extracellular matrix	cellular component	GO:0062023	428	4	19108	49	GPC5,LAMA4,PTPRZ1,APOA1
2.384e-02	-3.74	cellular response to fibroblast growth factor stimulus	biological process	GO:0044344	87	2	18204	50	FGFRL1,FGFR3
2.386e-02	-3.74	STX7 (syntaxin 7)	protein interactions	8417	654	5	19454	49	ELOVL2,GJA1,FARP1,PLPP3,USP6NL
2.387e-02	-3.74	GPCRKINASE	prints domains	PR00717	7	1	5227	18	GRK5
2.391e-02	-3.73	SCN4A (sodium voltage-gated channel alpha subunit 4)	protein interactions	6329	95	2	19454	49	SNTB1,GJA1
2.391e-02	-3.73	PNPLA6 (patatin like phospholipase domain containing 6)	protein interactions	10908	95	2	19454	49	GRK5,PRKN
2.391e-02	-3.73	LIMK1 (LIM domain kinase 1)	protein interactions	3984	95	2	19454	49	PRKN,CTBP1
2.391e-02	-3.73	KIF21A (kinesin family member 21A)	protein interactions	55605	95	2	19454	49	PRKN,MSI2
2.391e-02	-3.73	ZACN (zinc activated ion channel)	protein interactions	353174	95	2	19454	49	QKI,GJA1
2.391e-02	-3.73	MPP7 (MAGUK p55 scaffold protein 7)	protein interactions	143098	95	2	19454	49	AMOT,GJA1
2.403e-02	-3.73	SPTAN1 (spectrin alpha, non-erythrocytic 1)	protein interactions	6709	437	4	19454	49	FKBP5,PRKN,GRK5,GJA1
2.404e-02	-3.73	DNA-bd_RFX	interpro domains	IPR003150	9	1	18521	50	RFX4
2.404e-02	-3.73	Band3_cytoplasmic_dom	interpro domains	IPR013769	9	1	18521	50	SLC4A4
2.429e-02	-3.72	stomach	COSMIC cancer mutations	stomach	15550	47	16828	47	SLC39A12,GRK5,EGF,MSI2,RFX4,LPIN2,CTBP1,PTPRZ1,TNS3,GPC5,SLC1A3,USP6NL,PRDM16,PREX2,NFIA,BCAR3,PTN,RORA,FARP1,SOX5,FGFRL1,SLC4A4,SNTB1,GPM6B,TRPS1,DGKB,LRIG1,SORCS2,ASPA,AMOT,NPAS3,SLC6A11,PREX1,LAMA4,FGFR3,ELOVL2,SLC1A2,FHOD3,APOA1,AQP4,GJA1,QKI,NCKAP5,NHSL1,UNC93A,FKBP5,ZBTB20
2.438e-02	-3.71	SPIN1 (spindlin 1)	protein interactions	10927	96	2	19454	49	PTN,GRK5
2.440e-02	-3.71	cell-cell signaling	biological process	GO:0007267	822	6	18204	50	FGFR3,FARP1,SLC1A2,PRKN,GJA1,SLC1A3
2.440e-02	-3.71	soft_tissue-striated_muscle-rhabdomyosarcoma	COSMIC cancer mutations	soft_tissue-striated_muscle-rhabdomyosarcoma	594	5	16828	47	TRPS1,PREX2,PRDM16,DGKB,GJA1
2.446e-02	-3.71	zinc ion import across plasma membrane	biological process	GO:0071578	9	1	18204	50	SLC39A12
2.446e-02	-3.71	tripeptide transmembrane transport	biological process	GO:0035443	9	1	18204	50	GJA1
2.446e-02	-3.71	regulation of intestinal cholesterol absorption	biological process	GO:0030300	9	1	18204	50	APOA1
2.446e-02	-3.71	regulation of protein localization to early endosome	biological process	GO:1902965	9	1	18204	50	EGF
2.446e-02	-3.71	diaphragm development	biological process	GO:0060539	9	1	18204	50	FGFRL1
2.446e-02	-3.71	regulation of cerebellar granule cell precursor proliferation	biological process	GO:0021936	9	1	18204	50	EGF
2.446e-02	-3.71	glutathione transport	biological process	GO:0034635	9	1	18204	50	GJA1
2.446e-02	-3.71	positive regulation of protein localization to early endosome	biological process	GO:1902966	9	1	18204	50	EGF
2.452e-02	-3.71	NCOR2 (nuclear receptor corepressor 2)	protein interactions	9612	248	3	19454	49	NFIA,SOX5,CTBP1
2.456e-02	-3.71	Protein tyrosine phosphatase superfamily	gene3d domains	3.90.190.10	88	2	14470	40	TNS3,PTPRZ1
2.461e-02	-3.70	-	gene3d domains	1.25.40.610	9	1	14470	40	ADGRB3
2.470e-02	-3.70	WH-like_DNA-bd_sf	interpro domains	IPR036388	232	3	18521	50	PREX1,PREX2,RFX4
2.477e-02	-3.70	PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling	REACTOME pathways	R-HSA-6811558	87	2	10285	29	FGFR3,EGF
2.478e-02	-3.70	NUP93 (nucleoporin 93)	protein interactions	9688	249	3	19454	49	PRDM16,PRKN,FGFR3
2.478e-02	-3.70	MYO1B (myosin IB)	protein interactions	4430	249	3	19454	49	PRKN,FGFR3,PRDM16
2.478e-02	-3.70	EIF3E (eukaryotic translation initiation factor 3 subunit E)	protein interactions	3646	249	3	19454	49	PRDM16,PRKN,MSI2
2.483e-02	-3.70	chronic_lymphocytic_leukaemia-small_lymphocytic_lymphoma	COSMIC cancer mutations	chronic_lymphocytic_leukaemia-small_lymphocytic_lymphoma	3511	16	16828	47	SNTB1,EGF,SLC4A4,LAMA4,FGFRL1,DGKB,FHOD3,PREX2,NCKAP5,PTPRZ1,NPAS3,ASPA,MSI2,SLC1A3,GPC5,TNS3
2.483e-02	-3.70	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-chronic_lymphocytic_leukaemia-small_lymphocytic_lymphoma	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-chronic_lymphocytic_leukaemia-small_lymphocytic_lymphoma	3511	16	16828	47	PREX2,FHOD3,DGKB,FGFRL1,LAMA4,SLC4A4,SNTB1,EGF,GPC5,TNS3,SLC1A3,ASPA,MSI2,PTPRZ1,NCKAP5,NPAS3
2.486e-02	-3.69	PCGF5 (polycomb group ring finger 5)	protein interactions	84333	97	2	19454	49	CTBP1,QKI
2.486e-02	-3.69	LIN7C (lin-7 homolog C, crumbs cell polarity complex component)	protein interactions	55327	97	2	19454	49	AMOT,PRKN
2.486e-02	-3.69	skin-chest-malignant_melanoma-superficial_spreading	COSMIC cancer mutations	skin-chest-malignant_melanoma-superficial_spreading	9	1	16828	47	PREX2
2.486e-02	-3.69	epidermal_nevus	COSMIC cancer mutations	epidermal_nevus	9	1	16828	47	FGFR3
2.486e-02	-3.69	skin-upper_leg-malignant_melanoma-superficial_spreading	COSMIC cancer mutations	skin-upper_leg-malignant_melanoma-superficial_spreading	9	1	16828	47	PREX2
2.486e-02	-3.69	compound	COSMIC cancer mutations	compound	9	1	16828	47	FGFR3
2.486e-02	-3.69	skin-other-seborrhoeic_keratosis	COSMIC cancer mutations	skin-other-seborrhoeic_keratosis	9	1	16828	47	FGFR3
2.486e-02	-3.69	skin-benign_melanocytic_nevus-congenital	COSMIC cancer mutations	skin-benign_melanocytic_nevus-congenital	9	1	16828	47	FGFR3
2.486e-02	-3.69	ovary-low_malignant_potential_(borderline)_tumour-Brenner_tumour	COSMIC cancer mutations	ovary-low_malignant_potential_(borderline)_tumour-Brenner_tumour	9	1	16828	47	FGFR3
2.486e-02	-3.69	in_situ_epithelial_neoplasm	COSMIC cancer mutations	in_situ_epithelial_neoplasm	9	1	16828	47	FGFR3
2.486e-02	-3.69	Bowen_disease	COSMIC cancer mutations	Bowen_disease	9	1	16828	47	FGFR3
2.491e-02	-3.69	PLA2G1B (phospholipase A2 group IB)	protein interactions	5319	10	1	19454	49	PRKN
2.491e-02	-3.69	CFAP46 (cilia and flagella associated protein 46)	protein interactions	54777	10	1	19454	49	PRKN
2.491e-02	-3.69	CFAP57 (cilia and flagella associated protein 57)	protein interactions	149465	10	1	19454	49	PRKN
2.491e-02	-3.69	CREBL2 (cAMP responsive element binding protein like 2)	protein interactions	1389	10	1	19454	49	PRKN
2.491e-02	-3.69	IGKV2-40 (immunoglobulin kappa variable 2-40)	protein interactions	28916	10	1	19454	49	APOA1
2.491e-02	-3.69	CAPN5 (calpain 5)	protein interactions	726	10	1	19454	49	PRKN
2.491e-02	-3.69	GUCA1B (guanylate cyclase activator 1B)	protein interactions	2979	10	1	19454	49	CTBP1
2.491e-02	-3.69	GPLD1 (glycosylphosphatidylinositol specific phospholipase D1)	protein interactions	2822	10	1	19454	49	APOA1
2.491e-02	-3.69	CDKL4 (cyclin dependent kinase like 4)	protein interactions	344387	10	1	19454	49	FKBP5
2.491e-02	-3.69	Mrpl13 (mitochondrial ribosomal protein L13)	protein interactions	68537	10	1	19454	49	QKI
2.491e-02	-3.69	BANK1 (B cell scaffold protein with ankyrin repeats 1)	protein interactions	55024	10	1	19454	49	PRKN
2.491e-02	-3.69	Hsp90aa1 (heat shock protein 90, alpha (cytosolic), class A member 1)	protein interactions	15519	10	1	19454	49	QKI
2.491e-02	-3.69	ZNF561 (zinc finger protein 561)	protein interactions	93134	10	1	19454	49	PRKN
2.491e-02	-3.69	SESN3 (sestrin 3)	protein interactions	143686	10	1	19454	49	PRKN
2.491e-02	-3.69	P2rx7 (purinergic receptor P2X 7)	protein interactions	29665	10	1	19454	49	PTPRZ1
2.491e-02	-3.69	TENT4A (terminal nucleotidyltransferase 4A)	protein interactions	11044	10	1	19454	49	PRKN
2.491e-02	-3.69	MACC1 (MET transcriptional regulator MACC1)	protein interactions	346389	10	1	19454	49	PRKN
2.491e-02	-3.69	IL12RB2 (interleukin 12 receptor subunit beta 2)	protein interactions	3595	10	1	19454	49	PRKN
2.491e-02	-3.69	HAS1 (hyaluronan synthase 1)	protein interactions	3036	10	1	19454	49	PRKN
2.491e-02	-3.69	HMCN1 (hemicentin 1)	protein interactions	83872	10	1	19454	49	PRKN
2.491e-02	-3.69	RNF17 (ring finger protein 17)	protein interactions	56163	10	1	19454	49	PRKN
2.491e-02	-3.69	ARHGAP27 (Rho GTPase activating protein 27)	protein interactions	201176	10	1	19454	49	PRKN
2.491e-02	-3.69	Eps15 (epidermal growth factor receptor pathway substrate 15)	protein interactions	13858	10	1	19454	49	PRKN
2.496e-02	-3.69	DNA-binding transcription factor activity, RNA polymerase II-specific	molecular function	GO:0000981	1355	8	18094	48	RFX4,SOX5,PRDM16,TRPS1,RORA,ZBTB20,NPAS3,NFIA
2.501e-02	-3.69	RFX_DNA_binding	pfam domains	PF02257	9	1	17795	50	RFX4
2.501e-02	-3.69	Band_3_cyto	pfam domains	PF07565	9	1	17795	50	SLC4A4
2.501e-02	-3.69	regulation of cell migration	biological process	GO:0030334	1061	7	18204	50	PLPP3,EGF,PTN,AMOT,GJA1,PREX1,LAMA4
2.501e-02	-3.69	RHOG (ras homolog family member G)	protein interactions	391	902	6	19454	49	USP6NL,PREX2,PRKN,ELOVL2,FARP1,GJA1
2.510e-02	-3.68	Formation of annular gap junctions	REACTOME pathways	R-HSA-196025	9	1	10285	29	GJA1
2.515e-02	-3.68	monoatomic cation transmembrane transporter activity	molecular function	GO:0008324	630	5	18094	48	SLC1A3,SLC4A4,SLC39A12,SLC1A2,SLC6A11
2.525e-02	-3.68	large_intestine-colon	COSMIC cancer mutations	large_intestine-colon	1291	8	16828	47	LAMA4,PREX1,SNTB1,PTPRZ1,FHOD3,DGKB,USP6NL,ZBTB20
2.533e-02	-3.68	PPASE_TENSIN	prosite domains	PS51181	8	1	12186	39	TNS3
2.533e-02	-3.68	DAD	prosite domains	PS51231	8	1	12186	39	FHOD3
2.533e-02	-3.68	GATA_ZN_FINGER_1	prosite domains	PS00344	8	1	12186	39	TRPS1
2.533e-02	-3.68	C2_TENSIN	prosite domains	PS51182	8	1	12186	39	TNS3
2.534e-02	-3.68	FRS2 (fibroblast growth factor receptor substrate 2)	protein interactions	10818	98	2	19454	49	FGFR3,GJA1
2.534e-02	-3.68	WDCP (WD repeat and coiled coil containing)	protein interactions	80304	98	2	19454	49	CTBP1,AMOT
2.534e-02	-3.68	GCC1 (GRIP and coiled-coil domain containing 1)	protein interactions	79571	98	2	19454	49	GJA1,PRKN
2.534e-02	-3.68	ORC4 (origin recognition complex subunit 4)	protein interactions	5000	98	2	19454	49	CTBP1,PRKN
2.534e-02	-3.68	DMD (dystrophin)	protein interactions	1756	98	2	19454	49	SNTB1,TNS3
2.534e-02	-3.68	MED27 (mediator complex subunit 27)	protein interactions	9442	98	2	19454	49	QKI,SOX5
2.534e-02	-3.68	MAP4K5 (mitogen-activated protein kinase kinase kinase kinase 5)	protein interactions	11183	98	2	19454	49	GJA1,PRKN
2.534e-02	-3.68	HSPA12A (heat shock protein family A (Hsp70) member 12A)	protein interactions	259217	98	2	19454	49	FGFR3,PRKN
2.534e-02	-3.68	MB21D2 (Mab-21 domain containing 2)	protein interactions	151963	98	2	19454	49	GJA1,PRKN
2.534e-02	-3.68	regulation of intracellular signal transduction	biological process	GO:1902531	1832	10	18204	50	PREX2,PREX1,PRKN,AMOT,RORA,GJA1,APOA1,BCAR3,FGFR3,EGF
2.536e-02	-3.67	perineuronal net	cellular component	GO:0072534	10	1	19108	49	PTPRZ1
2.539e-02	-3.67	regulation of purine nucleotide metabolic process	biological process	GO:1900542	90	2	18204	50	SLC4A4,ZBTB20
2.542e-02	-3.67	pancreas-carcinoma-ductal_carcinoma	COSMIC cancer mutations	pancreas-carcinoma-ductal_carcinoma	15565	47	16828	47	GPM6B,TRPS1,DGKB,LRIG1,FGFRL1,SOX5,SLC4A4,SNTB1,SLC6A11,SORCS2,ASPA,AMOT,NPAS3,FHOD3,APOA1,PREX1,LAMA4,FGFR3,ELOVL2,SLC1A2,NHSL1,UNC93A,ZBTB20,FKBP5,AQP4,GJA1,QKI,NCKAP5,SLC39A12,GRK5,EGF,TNS3,GPC5,SLC1A3,USP6NL,MSI2,RFX4,LPIN2,CTBP1,PTPRZ1,PREX2,NFIA,PRDM16,PTN,RORA,FARP1,BCAR3
2.557e-02	-3.67	RAC2 (Rac family small GTPase 2)	protein interactions	5880	666	5	19454	49	USP6NL,TNS3,GJA1,FARP1,SLC1A3
2.568e-02	-3.66	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-acute_lymphoblastic_leukaemia	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-acute_lymphoblastic_leukaemia	2081	11	16828	47	FGFRL1,SOX5,SLC4A4,FGFR3,GRK5,CTBP1,PTPRZ1,PREX2,NFIA,FHOD3,TRPS1
2.581e-02	-3.66	PRRC2C (proline rich coiled-coil 2C)	protein interactions	23215	253	3	19454	49	PRKN,SOX5,FKBP5
2.581e-02	-3.66	connective tissue development	biological process	GO:0061448	232	3	18204	50	SOX5,FGFR3,NFIA
2.582e-02	-3.66	ZFHX3 (zinc finger homeobox 3)	protein interactions	463	99	2	19454	49	TRPS1,SOX5
2.582e-02	-3.66	PRKACG (protein kinase cAMP-activated catalytic subunit gamma)	protein interactions	5568	99	2	19454	49	PRKN,FKBP5
2.583e-02	-3.66	abdomen	COSMIC cancer mutations	abdomen	603	5	16828	47	PREX2,PRDM16,FGFR3,SLC6A11,LRIG1
2.584e-02	-3.66	Signaling by FGFR	REACTOME pathways	R-HSA-190236	89	2	10285	29	FGFR3,FGFRL1
2.592e-02	-3.65	regulation of nucleotide metabolic process	biological process	GO:0006140	91	2	18204	50	ZBTB20,SLC4A4
2.600e-02	-3.65	Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain	gene3d domains	1.10.10.10	232	3	14470	40	PREX2,PREX1,RFX4
2.612e-02	-3.65	transmembrane transporter activity	molecular function	GO:0022857	1110	7	18094	48	SLC1A3,SLC1A2,SLC39A12,SLC6A11,GJA1,SLC4A4,AQP4
2.622e-02	-3.64	VAPB (VAMP associated protein B and C)	protein interactions	9217	449	4	19454	49	SLC1A3,FGFR3,PRKN,GJA1
2.622e-02	-3.64	FK506 binding	molecular function	GO:0005528	10	1	18094	48	FKBP5
2.630e-02	-3.64	SFN (stratifin)	protein interactions	2810	671	5	19454	49	PRKN,NFIA,AMOT,TNS3,USP6NL
2.630e-02	-3.64	CIC (capicua transcriptional repressor)	protein interactions	23152	671	5	19454	49	NFIA,FARP1,TRPS1,CTBP1,SOX5
2.630e-02	-3.64	PLG (plasminogen)	protein interactions	5340	100	2	19454	49	PRKN,AMOT
2.630e-02	-3.64	PIK3C3 (phosphatidylinositol 3-kinase catalytic subunit type 3)	protein interactions	5289	100	2	19454	49	PRKN,GJA1
2.630e-02	-3.64	DTNB (dystrobrevin beta)	protein interactions	1838	100	2	19454	49	SNTB1,TNS3
2.630e-02	-3.64	UMPS (uridine monophosphate synthetase)	protein interactions	7372	100	2	19454	49	TNS3,PRKN
2.631e-02	-3.64	eye	COSMIC cancer mutations	eye	606	5	16828	47	GRK5,FGFR3,FGFRL1,PREX1,PREX2
2.637e-02	-3.64	intracellular signaling cassette	biological process	GO:0141124	837	6	18204	50	APOA1,PREX2,FGFR3,EGF,FARP1,BCAR3
2.638e-02	-3.64	PI3K/AKT Signaling in Cancer	REACTOME pathways	R-HSA-2219528	90	2	10285	29	FGFR3,EGF
2.645e-02	-3.63	regulation of embryonic development	biological process	GO:0045995	92	2	18204	50	AMOT,LAMA4
2.646e-02	-3.63	human chr6p24.2	chromosome location	human chr6p24.2	14	1	26134	50	ELOVL2
2.666e-02	-3.62	Ig_sub2	interpro domains	IPR003598	239	3	18521	50	FGFRL1,FGFR3,LRIG1
2.668e-02	-3.62	HCO3_transpt_euk	interpro domains	IPR003020	10	1	18521	50	SLC4A4
2.668e-02	-3.62	E3_UB_ligase_RBR	interpro domains	IPR031127	10	1	18521	50	PRKN
2.668e-02	-3.62	MIP_CS	interpro domains	IPR022357	10	1	18521	50	AQP4
2.668e-02	-3.62	PAS_fold_3	interpro domains	IPR013655	10	1	18521	50	NPAS3
2.668e-02	-3.62	PTrfase/Anion_transptr	interpro domains	IPR016152	10	1	18521	50	SLC4A4
2.668e-02	-3.62	Diacylglycerol_kin_accessory	interpro domains	IPR000756	10	1	18521	50	DGKB
2.668e-02	-3.62	HCO3_transpt-like_TM_dom	interpro domains	IPR011531	10	1	18521	50	SLC4A4
2.668e-02	-3.62	DGK	interpro domains	IPR037607	10	1	18521	50	DGKB
2.668e-02	-3.62	PA_PP_rel	interpro domains	IPR043216	10	1	18521	50	PLPP3
2.679e-02	-3.62	AMPD2 (adenosine monophosphate deaminase 2)	protein interactions	271	101	2	19454	49	CTBP1,PRKN
2.679e-02	-3.62	STAMBP (STAM binding protein)	protein interactions	10617	101	2	19454	49	PRKN,GJA1
2.679e-02	-3.62	CLEC4A (C-type lectin domain family 4 member A)	protein interactions	50856	101	2	19454	49	FGFRL1,FGFR3
2.679e-02	-3.62	MYO9B (myosin IXB)	protein interactions	4650	101	2	19454	49	PRKN,GRK5
2.679e-02	-3.62	ILKAP (ILK associated serine/threonine phosphatase)	protein interactions	80895	101	2	19454	49	PRKN,FGFR3
2.697e-02	-3.61	FLOT1 (flotillin 1)	protein interactions	10211	453	4	19454	49	FARP1,PRKN,USP6NL,SOX5
2.697e-02	-3.61	regulation of endothelial cell migration	biological process	GO:0010594	236	3	18204	50	PLPP3,EGF,PTN
2.701e-02	-3.61	embryonal	COSMIC cancer mutations	embryonal	2659	13	16828	47	PREX2,NFIA,RORA,DGKB,PRDM16,SORCS2,FGFRL1,FGFR3,AQP4,ELOVL2,GRK5,NPAS3,PTPRZ1
2.701e-02	-3.61	soft_tissue-striated_muscle-rhabdomyosarcoma-embryonal	COSMIC cancer mutations	soft_tissue-striated_muscle-rhabdomyosarcoma-embryonal	2659	13	16828	47	SORCS2,AQP4,NPAS3,PTPRZ1,RORA,PRDM16,FGFRL1,FGFR3,ELOVL2,GRK5,PREX2,NFIA,DGKB
2.714e-02	-3.61	cellular response to manganese ion	biological process	GO:0071287	10	1	18204	50	PRKN
2.714e-02	-3.61	regulation of CoA-transferase activity	biological process	GO:1905918	10	1	18204	50	APOA1
2.714e-02	-3.61	regulation of mesenchymal stem cell differentiation	biological process	GO:2000739	10	1	18204	50	SOX5
2.714e-02	-3.61	regulation of intestinal lipid absorption	biological process	GO:1904729	10	1	18204	50	APOA1
2.714e-02	-3.61	positive regulation of receptor clustering	biological process	GO:1903911	10	1	18204	50	FARP1
2.714e-02	-3.61	protein oxidation	biological process	GO:0018158	10	1	18204	50	APOA1
2.714e-02	-3.61	alpha-linolenic acid metabolic process	biological process	GO:0036109	10	1	18204	50	ELOVL2
2.714e-02	-3.61	high-density lipoprotein particle assembly	biological process	GO:0034380	10	1	18204	50	APOA1
2.714e-02	-3.61	regulation of atrial cardiac muscle cell membrane depolarization	biological process	GO:0060371	10	1	18204	50	GJA1
2.714e-02	-3.61	regulation of mesodermal cell differentiation	biological process	GO:1905770	10	1	18204	50	GJA1
2.714e-02	-3.61	positive regulation of hepatocyte proliferation	biological process	GO:2000347	10	1	18204	50	PTN
2.714e-02	-3.61	protein K29-linked ubiquitination	biological process	GO:0035519	10	1	18204	50	PRKN
2.714e-02	-3.61	otolith development	biological process	GO:0048840	10	1	18204	50	LRIG1
2.715e-02	-3.61	MTNAP1 (mitochondrial nucleoid associated protein 1)	protein interactions	55028	258	3	19454	49	SLC39A12,PRKN,FARP1
2.724e-02	-3.60	GATAZNFINGER	prints domains	PR00619	8	1	5227	18	TRPS1
2.727e-02	-3.60	anatomical structure maturation	biological process	GO:0071695	237	3	18204	50	GJA1,FGFR3,ADGRB3
2.728e-02	-3.60	TNFRSF10C (TNF receptor superfamily member 10c)	protein interactions	8794	102	2	19454	49	APOA1,PLPP3
2.728e-02	-3.60	FNTB (farnesyltransferase, CAAX box, subunit beta)	protein interactions	2342	102	2	19454	49	PRKN,LPIN2
2.728e-02	-3.60	UFSP2 (UFM1 specific peptidase 2)	protein interactions	55325	102	2	19454	49	LRIG1,PRKN
2.728e-02	-3.60	MAT2B (methionine adenosyltransferase 2 non-catalytic beta subunit)	protein interactions	27430	102	2	19454	49	PRKN,TNS3
2.728e-02	-3.60	MIR7-1 (microRNA 7-1)	protein interactions	407043	102	2	19454	49	QKI,MSI2
2.728e-02	-3.60	PIK3R4 (phosphoinositide-3-kinase regulatory subunit 4)	protein interactions	30849	102	2	19454	49	GJA1,PRKN
2.731e-02	-3.60	Helical hairpin bin	gene3d domains	1.10.287.570	10	1	14470	40	SLC4A4
2.737e-02	-3.60	SLC9A2 (solute carrier family 9 member A2)	protein interactions	6549	11	1	19454	49	PRKN
2.737e-02	-3.60	CCDC17 (coiled-coil domain containing 17)	protein interactions	149483	11	1	19454	49	FGFR3
2.737e-02	-3.60	DDT (D-dopachrome tautomerase)	protein interactions	1652	11	1	19454	49	PRKN
2.737e-02	-3.60	ABCA13 (ATP binding cassette subfamily A member 13)	protein interactions	154664	11	1	19454	49	APOA1
2.737e-02	-3.60	GAL3ST1 (galactose-3-O-sulfotransferase 1)	protein interactions	9514	11	1	19454	49	LRIG1
2.737e-02	-3.60	CACNA1D (calcium voltage-gated channel subunit alpha1 D)	protein interactions	776	11	1	19454	49	PRKN
2.737e-02	-3.60	C22orf42 (chromosome 22 open reading frame 42)	protein interactions	150297	11	1	19454	49	PRKN
2.737e-02	-3.60	ZNF84 (zinc finger protein 84)	protein interactions	7637	11	1	19454	49	PRKN
2.737e-02	-3.60	Gtf2e2 (general transcription factor II E, polypeptide 2 (beta subunit))	protein interactions	68153	11	1	19454	49	NHSL1
2.737e-02	-3.60	LCORL (ligand dependent nuclear receptor corepressor like)	protein interactions	254251	11	1	19454	49	CTBP1
2.737e-02	-3.60	EVA1A (eva-1 homolog A, regulator of programmed cell death)	protein interactions	84141	11	1	19454	49	PTN
2.737e-02	-3.60	TBCEL (tubulin folding cofactor E like)	protein interactions	219899	11	1	19454	49	PRKN
2.737e-02	-3.60	DNAH12 (dynein axonemal heavy chain 12)	protein interactions	201625	11	1	19454	49	PRKN
2.737e-02	-3.60	DNAH9 (dynein axonemal heavy chain 9)	protein interactions	1770	11	1	19454	49	PRKN
2.737e-02	-3.60	CYP1A2 (cytochrome P450 family 1 subfamily A member 2)	protein interactions	1544	11	1	19454	49	PRKN
2.737e-02	-3.60	DNAH8 (dynein axonemal heavy chain 8)	protein interactions	1769	11	1	19454	49	PRKN
2.737e-02	-3.60	HYDIN (HYDIN axonemal central pair apparatus protein)	protein interactions	54768	11	1	19454	49	PRKN
2.737e-02	-3.60	IL7 (interleukin 7)	protein interactions	3574	11	1	19454	49	QKI
2.737e-02	-3.60	DAZ1 (deleted in azoospermia 1)	protein interactions	1617	11	1	19454	49	QKI
2.737e-02	-3.60	ENOSF1 (enolase superfamily member 1)	protein interactions	55556	11	1	19454	49	PRKN
2.742e-02	-3.60	MARK2 (microtubule affinity regulating kinase 2)	protein interactions	2011	259	3	19454	49	SNTB1,PRKN,GJA1
2.742e-02	-3.60	positive regulation of catabolic process	biological process	GO:0009896	622	5	18204	50	SLC4A4,QKI,EGF,PRKN,ZBTB20
2.759e-02	-3.59	chiasm	COSMIC cancer mutations	chiasm	10	1	16828	47	QKI
2.759e-02	-3.59	lung-carcinoma-pleomorphic_carcinoma	COSMIC cancer mutations	lung-carcinoma-pleomorphic_carcinoma	10	1	16828	47	FGFR3
2.759e-02	-3.59	skin-back-malignant_melanoma-nodular	COSMIC cancer mutations	skin-back-malignant_melanoma-nodular	10	1	16828	47	PREX2
2.759e-02	-3.59	intradermal	COSMIC cancer mutations	intradermal	10	1	16828	47	FGFR3
2.759e-02	-3.59	cervix-in_situ_neoplasm-cervical_intraepithelial_neoplasia_Grade_III	COSMIC cancer mutations	cervix-in_situ_neoplasm-cervical_intraepithelial_neoplasia_Grade_III	10	1	16828	47	FGFR3
2.759e-02	-3.59	cervical_intraepithelial_neoplasia_Grade_III	COSMIC cancer mutations	cervical_intraepithelial_neoplasia_Grade_III	10	1	16828	47	FGFR3
2.759e-02	-3.59	renal_cell_carcinoma_unclassified	COSMIC cancer mutations	renal_cell_carcinoma_unclassified	10	1	16828	47	FGFR3
2.759e-02	-3.59	kidney-carcinoma-renal_cell_carcinoma_unclassified	COSMIC cancer mutations	kidney-carcinoma-renal_cell_carcinoma_unclassified	10	1	16828	47	FGFR3
2.762e-02	-3.59	trunk	COSMIC cancer mutations	trunk	3554	16	16828	47	PRDM16,SOX5,FGFR3,EGF,SNTB1,PREX2,TRPS1,DGKB,AMOT,NPAS3,PTPRZ1,NCKAP5,UNC93A,SLC6A11,SLC1A3,FKBP5
2.766e-02	-3.59	PKD	smart domains	SM00089	8	1	9717	34	SORCS2
2.766e-02	-3.59	PTEN_C2	smart domains	SM01326	8	1	9717	34	TNS3
2.769e-02	-3.59	postsynaptic density membrane	cellular component	GO:0098839	101	2	19108	49	ADGRB3,SORCS2
2.775e-02	-3.58	HCO3_cotransp	pfam domains	PF00955	10	1	17795	50	SLC4A4
2.775e-02	-3.58	PAS_3	pfam domains	PF08447	10	1	17795	50	NPAS3
2.775e-02	-3.58	DAGK_acc	pfam domains	PF00609	10	1	17795	50	DGKB
2.778e-02	-3.58	NPRL3 (NPR3 like, GATOR1 complex subunit)	protein interactions	8131	103	2	19454	49	PRKN,CTBP1
2.778e-02	-3.58	NEK9 (NIMA related kinase 9)	protein interactions	91754	103	2	19454	49	PRKN,AMOT
2.778e-02	-3.58	BACH1 (BTB domain and CNC homolog 1)	protein interactions	571	103	2	19454	49	FGFRL1,PRKN
2.778e-02	-3.58	TXNRD1 (thioredoxin reductase 1)	protein interactions	7296	103	2	19454	49	PRKN,FKBP5
2.778e-02	-3.58	PLEKHA1 (pleckstrin homology domain containing A1)	protein interactions	59338	103	2	19454	49	GJA1,PRKN
2.781e-02	-3.58	oesophagus	COSMIC cancer mutations	oesophagus	14970	46	16828	47	APOA1,FHOD3,SLC1A2,PREX1,LAMA4,FGFR3,ELOVL2,FKBP5,ZBTB20,NHSL1,UNC93A,GJA1,QKI,NCKAP5,AQP4,DGKB,LRIG1,GPM6B,TRPS1,SNTB1,SOX5,FGFRL1,SLC4A4,SLC6A11,AMOT,NPAS3,SORCS2,ASPA,PREX2,NFIA,PRDM16,PTN,RORA,FARP1,BCAR3,GRK5,EGF,SLC39A12,SLC1A3,USP6NL,TNS3,GPC5,RFX4,LPIN2,CTBP1,PTPRZ1
2.785e-02	-3.58	Gap junction degradation	REACTOME pathways	R-HSA-190873	10	1	10285	29	GJA1
2.785e-02	-3.58	Signaling by FGFR3 fusions in cancer	REACTOME pathways	R-HSA-8853334	10	1	10285	29	FGFR3
2.785e-02	-3.58	Linoleic acid (LA) metabolism	REACTOME pathways	R-HSA-2046105	10	1	10285	29	ELOVL2
2.785e-02	-3.58	Bicarbonate transporters	REACTOME pathways	R-HSA-425381	10	1	10285	29	SLC4A4
2.786e-02	-3.58	perisynaptic extracellular matrix	cellular component	GO:0098966	11	1	19108	49	PTPRZ1
2.793e-02	-3.58	PPP2CA (protein phosphatase 2 catalytic subunit alpha)	protein interactions	5515	458	4	19454	49	NHSL1,PRDM16,PRKN,PTN
2.802e-02	-3.58	RNA polymerase II transcription regulatory region sequence-specific DNA binding	molecular function	GO:0000977	1385	8	18094	48	RFX4,TRPS1,RORA,PRDM16,SOX5,NFIA,ZBTB20,NPAS3
2.807e-02	-3.57	response to fibroblast growth factor	biological process	GO:0071774	95	2	18204	50	FGFR3,FGFRL1
2.814e-02	-3.57	basolateral plasma membrane	cellular component	GO:0016323	257	3	19108	49	AQP4,PLPP3,SLC4A4
2.824e-02	-3.57	MTA1 (metastasis associated 1)	protein interactions	9112	262	3	19454	49	PRKN,PRDM16,TRPS1
2.828e-02	-3.57	ARHGAP18 (Rho GTPase activating protein 18)	protein interactions	93663	104	2	19454	49	PRKN,PREX2
2.828e-02	-3.57	MYCBP (MYC binding protein)	protein interactions	26292	104	2	19454	49	PREX1,PTN
2.832e-02	-3.56	human chr8q24.12	chromosome location	human chr8q24.12	15	1	26134	50	SNTB1
2.835e-02	-3.56	EGFR tyrosine kinase inhibitor resistance	KEGG pathways	hsa01521	79	2	7161	24	EGF,FGFR3
2.835e-02	-3.56	EGFR tyrosine kinase inhibitor resistance	KEGG pathways	ko01521	79	2	7161	24	EGF,FGFR3
2.845e-02	-3.56	RFX_DBD	prosite domains	PS51526	9	1	12186	39	RFX4
2.845e-02	-3.56	protein domain specific binding	molecular function	GO:0019904	651	5	18094	48	SNTB1,CTBP1,PRKN,TRPS1,QKI
2.851e-02	-3.56	ARF4 (ADP ribosylation factor 4)	protein interactions	378	263	3	19454	49	FGFR3,PRKN,GRK5
2.851e-02	-3.56	CACYBP (calcyclin binding protein)	protein interactions	27101	263	3	19454	49	FKBP5,PRKN,FGFR3
2.859e-02	-3.55	Negative regulation of the PI3K/AKT network	REACTOME pathways	R-HSA-199418	94	2	10285	29	EGF,FGFR3
2.868e-02	-3.55	molecular function activator activity	molecular function	GO:0140677	1132	7	18094	48	EGF,PREX1,APOA1,ADGRB3,PTN,PREX2,USP6NL
2.878e-02	-3.55	PTPA (protein phosphatase 2 phosphatase activator)	protein interactions	5524	105	2	19454	49	PRKN,AMOT
2.878e-02	-3.55	IRF2BP2 (interferon regulatory factor 2 binding protein 2)	protein interactions	359948	105	2	19454	49	PRKN,NFIA
2.878e-02	-3.55	CEP72 (centrosomal protein 72)	protein interactions	55722	105	2	19454	49	AMOT,PRKN
2.879e-02	-3.55	TECR (trans-2,3-enoyl-CoA reductase)	protein interactions	9524	264	3	19454	49	PRDM16,FGFR3,PRKN
2.880e-02	-3.55	oligopeptide transmembrane transporter activity	molecular function	GO:0035673	11	1	18094	48	GJA1
2.880e-02	-3.55	ATP-dependent diacylglycerol kinase activity	molecular function	GO:0004143	11	1	18094	48	DGKB
2.880e-02	-3.55	structural constituent of myelin sheath	molecular function	GO:0019911	11	1	18094	48	GPM6B
2.880e-02	-3.55	sulfur amino acid transmembrane transporter activity	molecular function	GO:0000099	11	1	18094	48	SLC1A2
2.892e-02	-3.54	Bile Acid Indirect Signalling Pathway	SMPDB pathways	SMP0086851	8	1	1369	5	FGFR3
2.907e-02	-3.54	viral process	biological process	GO:0016032	243	3	18204	50	NFIA,CTBP1,USP6NL
2.917e-02	-3.53	acylglycerol metabolic process	biological process	GO:0006639	97	2	18204	50	DGKB,LPIN2
2.917e-02	-3.53	nerve development	biological process	GO:0021675	97	2	18204	50	LRIG1,SLC1A3
2.929e-02	-3.53	HSP90AB2P (heat shock protein 90 alpha family class B member 2, pseudogene)	protein interactions	391634	106	2	19454	49	PRKN,FKBP5
2.929e-02	-3.53	CWC22 (CWC22 spliceosome associated protein homolog)	protein interactions	57703	106	2	19454	49	PRKN,GRK5
2.929e-02	-3.53	FLG2 (filaggrin 2)	protein interactions	388698	106	2	19454	49	FGFRL1,PRKN
2.931e-02	-3.53	GBD/FH3_dom	interpro domains	IPR014768	11	1	18521	50	FHOD3
2.931e-02	-3.53	PKD_dom	interpro domains	IPR000601	11	1	18521	50	SORCS2
2.931e-02	-3.53	PKD_dom_sf	interpro domains	IPR035986	11	1	18521	50	SORCS2
2.931e-02	-3.53	GAIN_dom_N	interpro domains	IPR032471	11	1	18521	50	ADGRB3
2.935e-02	-3.53	HNRNPUL2 (heterogeneous nuclear ribonucleoprotein U like 2)	protein interactions	221092	266	3	19454	49	FGFR3,PRKN,QKI
2.940e-02	-3.53	breast-carcinoma-basal_(triple-negative)_carcinoma	COSMIC cancer mutations	breast-carcinoma-basal_(triple-negative)_carcinoma	2981	14	16828	47	FHOD3,ELOVL2,SLC4A4,SLC39A12,FGFR3,LAMA4,PRDM16,EGF,UNC93A,TNS3,MSI2,NPAS3,AMOT,LPIN2
2.940e-02	-3.53	basal_(triple-negative)_carcinoma	COSMIC cancer mutations	basal_(triple-negative)_carcinoma	2981	14	16828	47	FHOD3,SLC4A4,FGFR3,SLC39A12,ELOVL2,PRDM16,LAMA4,EGF,UNC93A,TNS3,MSI2,NPAS3,LPIN2,AMOT
2.950e-02	-3.52	TYR_PHOSPHATASE_2	prosite domains	PS50056	84	2	12186	39	PTPRZ1,TNS3
2.964e-02	-3.52	arm	COSMIC cancer mutations	arm	1331	8	16828	47	FGFR3,SLC4A4,SNTB1,NPAS3,TRPS1,SLC6A11,FHOD3,ZBTB20
2.968e-02	-3.52	cell surface receptor protein tyrosine kinase signaling pathway	biological process	GO:0007169	428	4	18204	50	FGFRL1,FGFR3,EGF,BCAR3
2.972e-02	-3.52	neutral lipid metabolic process	biological process	GO:0006638	98	2	18204	50	DGKB,LPIN2
2.980e-02	-3.51	KIFAP3 (kinesin associated protein 3)	protein interactions	22920	107	2	19454	49	PRKN,NCKAP5
2.980e-02	-3.51	POLR3C (RNA polymerase III subunit C)	protein interactions	10623	107	2	19454	49	PRKN,PRDM16
2.980e-02	-3.51	CHMP2A (charged multivesicular body protein 2A)	protein interactions	27243	107	2	19454	49	FKBP5,MSI2
2.981e-02	-3.51	intracellular mRNA localization	biological process	GO:0008298	11	1	18204	50	QKI
2.981e-02	-3.51	dendrite arborization	biological process	GO:0140059	11	1	18204	50	PTN
2.981e-02	-3.51	Bergmann glial cell differentiation	biological process	GO:0060020	11	1	18204	50	PLPP3
2.981e-02	-3.51	protein K27-linked ubiquitination	biological process	GO:0044314	11	1	18204	50	PRKN
2.981e-02	-3.51	dopamine uptake	biological process	GO:0090494	11	1	18204	50	PRKN
2.981e-02	-3.51	synaptic vesicle clustering	biological process	GO:0097091	11	1	18204	50	CTBP1
2.981e-02	-3.51	ubiquitin recycling	biological process	GO:0010992	11	1	18204	50	PRKN
2.981e-02	-3.51	tripeptide transport	biological process	GO:0042939	11	1	18204	50	GJA1
2.981e-02	-3.51	glutamate secretion	biological process	GO:0014047	11	1	18204	50	GJA1
2.981e-02	-3.51	catecholamine uptake	biological process	GO:0090493	11	1	18204	50	PRKN
2.981e-02	-3.51	regulation of cell-cell adhesion involved in gastrulation	biological process	GO:0070587	11	1	18204	50	APOA1
2.981e-02	-3.51	negative regulation of heterotypic cell-cell adhesion	biological process	GO:0034115	11	1	18204	50	APOA1
2.981e-02	-3.51	peptidyl-methionine modification	biological process	GO:0018206	11	1	18204	50	APOA1
2.981e-02	-3.51	lipid phosphorylation	biological process	GO:0046834	11	1	18204	50	DGKB
2.982e-02	-3.51	TREM2 (triggering receptor expressed on myeloid cells 2)	protein interactions	54209	12	1	19454	49	APOA1
2.982e-02	-3.51	FSIP2 (fibrous sheath interacting protein 2)	protein interactions	401024	12	1	19454	49	PRKN
2.982e-02	-3.51	CA4 (carbonic anhydrase 4)	protein interactions	762	12	1	19454	49	SLC4A4
2.982e-02	-3.51	HEXD (hexosaminidase D)	protein interactions	284004	12	1	19454	49	PRKN
2.982e-02	-3.51	IL15 (interleukin 15)	protein interactions	3600	12	1	19454	49	LRIG1
2.982e-02	-3.51	ROBO4 (roundabout guidance receptor 4)	protein interactions	54538	12	1	19454	49	PRKN
2.982e-02	-3.51	Pcbp2 (poly(rC) binding protein 2)	protein interactions	18521	12	1	19454	49	FARP1
2.982e-02	-3.51	RHAG (Rh associated glycoprotein)	protein interactions	6005	12	1	19454	49	UNC93A
2.982e-02	-3.51	FBXO9 (F-box protein 9)	protein interactions	26268	12	1	19454	49	PRKN
2.982e-02	-3.51	CALN1 (calneuron 1)	protein interactions	83698	12	1	19454	49	PRKN
2.982e-02	-3.51	CCZ1B (CCZ1 homolog B, vacuolar protein trafficking and biogenesis associated)	protein interactions	221960	12	1	19454	49	PRKN
2.982e-02	-3.51	SLC48A1 (solute carrier family 48 member 1)	protein interactions	55652	12	1	19454	49	UNC93A
2.982e-02	-3.51	CDH11 (cadherin 11)	protein interactions	1009	12	1	19454	49	AMOT
2.982e-02	-3.51	PANK3 (pantothenate kinase 3)	protein interactions	79646	12	1	19454	49	PRKN
2.982e-02	-3.51	WDR87 (WD repeat domain 87)	protein interactions	83889	12	1	19454	49	PRKN
2.992e-02	-3.51	NSUN2 (NOP2/Sun RNA methyltransferase 2)	protein interactions	54888	268	3	19454	49	FGFR3,PRKN,FKBP5
3.018e-02	-3.50	human chr7p12.3	chromosome location	human chr7p12.3	16	1	26134	50	TNS3
3.020e-02	-3.50	AP2A1 (adaptor related protein complex 2 subunit alpha 1)	protein interactions	160	269	3	19454	49	GRK5,FGFR3,PRKN
3.020e-02	-3.50	AHSA1 (activator of HSP90 ATPase activity 1)	protein interactions	10598	269	3	19454	49	PRKN,FGFR3,FKBP5
3.020e-02	-3.50	PNN (pinin, desmosome associated protein)	protein interactions	5411	269	3	19454	49	GRK5,PRKN,CTBP1
3.028e-02	-3.50	regulation of neurotransmitter transport	biological process	GO:0051588	99	2	18204	50	GPM6B,PRKN
3.031e-02	-3.50	skin-neck-carcinoma-basal_cell_carcinoma	COSMIC cancer mutations	skin-neck-carcinoma-basal_cell_carcinoma	11	1	16828	47	FGFR3
3.031e-02	-3.50	kidney-other-oncocytoma	COSMIC cancer mutations	kidney-other-oncocytoma	11	1	16828	47	FGFR3
3.031e-02	-3.50	prostate-hyperplasia	COSMIC cancer mutations	prostate-hyperplasia	11	1	16828	47	FGFR3
3.031e-02	-3.50	skin-hand-malignant_melanoma-acral_lentiginous	COSMIC cancer mutations	skin-hand-malignant_melanoma-acral_lentiginous	11	1	16828	47	PREX2
3.031e-02	-3.50	oncocytoma	COSMIC cancer mutations	oncocytoma	11	1	16828	47	FGFR3
3.031e-02	-3.50	seborrhoeic_keratosis	COSMIC cancer mutations	seborrhoeic_keratosis	11	1	16828	47	FGFR3
3.031e-02	-3.50	skin-scalp-carcinoma-basal_cell_carcinoma	COSMIC cancer mutations	skin-scalp-carcinoma-basal_cell_carcinoma	11	1	16828	47	FGFR3
3.031e-02	-3.50	congenital	COSMIC cancer mutations	congenital	11	1	16828	47	FGFR3
3.031e-02	-3.50	skin-back-malignant_melanoma-superficial_spreading	COSMIC cancer mutations	skin-back-malignant_melanoma-superficial_spreading	11	1	16828	47	PREX2
3.031e-02	-3.50	pleomorphic_carcinoma	COSMIC cancer mutations	pleomorphic_carcinoma	11	1	16828	47	FGFR3
3.031e-02	-3.50	FKBP1A (FKBP prolyl isomerase 1A)	protein interactions	2280	108	2	19454	49	MSI2,CTBP1
3.031e-02	-3.50	PYGL (glycogen phosphorylase L)	protein interactions	5836	108	2	19454	49	FKBP5,PRKN
3.031e-02	-3.50	EN1 (engrailed homeobox 1)	protein interactions	2019	108	2	19454	49	TRPS1,NFIA
3.031e-02	-3.50	PAX8 (paired box 8)	protein interactions	7849	108	2	19454	49	TRPS1,NFIA
3.031e-02	-3.50	CAMKV (CaM kinase like vesicle associated)	protein interactions	79012	108	2	19454	49	FARP1,FKBP5
3.034e-02	-3.50	trans-synaptic signaling	biological process	GO:0099537	431	4	18204	50	PRKN,FARP1,SLC1A3,SLC1A2
3.035e-02	-3.49	synapse-associated extracellular matrix	cellular component	GO:0099535	12	1	19108	49	PTPRZ1
3.044e-02	-3.49	Prot-tyrosine_phosphatase-like	interpro domains	IPR029021	101	2	18521	50	PTPRZ1,TNS3
3.049e-02	-3.49	GAIN	pfam domains	PF16489	11	1	17795	50	ADGRB3
3.049e-02	-3.49	LRRCT	pfam domains	PF01463	11	1	17795	50	LRIG1
3.060e-02	-3.49	Creatine metabolism	REACTOME pathways	R-HSA-71288	11	1	10285	29	SLC6A11
3.075e-02	-3.48	Regulation of RAC1 activity	Pathway Interaction DB	rac1_reg_pathway	39	2	2226	16	PREX2,PREX1
3.083e-02	-3.48	DNMBP (dynamin binding protein)	protein interactions	23268	109	2	19454	49	AMOT,PRKN
3.083e-02	-3.48	SKIC2 (SKI2 subunit of superkiller complex)	protein interactions	6499	109	2	19454	49	FKBP5,PRKN
3.083e-02	-3.48	MIR34B (microRNA 34b)	protein interactions	407041	109	2	19454	49	QKI,MSI2
3.083e-02	-3.48	NT5C2 (5'-nucleotidase, cytosolic II)	protein interactions	22978	109	2	19454	49	PRKN,PREX2
3.083e-02	-3.48	PALLD (palladin, cytoskeletal associated protein)	protein interactions	23022	109	2	19454	49	PRKN,FKBP5
3.083e-02	-3.48	RABGAP1 (RAB GTPase activating protein 1)	protein interactions	23637	109	2	19454	49	GJA1,PRKN
3.083e-02	-3.48	ROR1 (receptor tyrosine kinase like orphan receptor 1)	protein interactions	4919	109	2	19454	49	USP6NL,GJA1
3.085e-02	-3.48	response to alkaloid	biological process	GO:0043279	100	2	18204	50	SLC1A3,SLC1A2
3.116e-02	-3.47	skin-scalp-malignant_melanoma	COSMIC cancer mutations	skin-scalp-malignant_melanoma	634	5	16828	47	SLC6A11,PREX2,LAMA4,NFIA,PTPRZ1
3.135e-02	-3.46	RBM33 (RNA binding motif protein 33)	protein interactions	155435	110	2	19454	49	SOX5,PRKN
3.135e-02	-3.46	RAB21 (RAB21, member RAS oncogene family)	protein interactions	23011	110	2	19454	49	FGFR3,PRKN
3.135e-02	-3.46	KIT (KIT proto-oncogene, receptor tyrosine kinase)	protein interactions	3815	110	2	19454	49	TNS3,BCAR3
3.135e-02	-3.46	SUGT1 (SGT1 homolog, MIS12 kinetochore complex assembly cochaperone)	protein interactions	10910	273	3	19454	49	PRKN,FGFR3,FKBP5
3.138e-02	-3.46	macrolide binding	molecular function	GO:0005527	12	1	18094	48	FKBP5
3.142e-02	-3.46	positive regulation of cold-induced thermogenesis	biological process	GO:0120162	101	2	18204	50	GJA1,PRDM16
3.142e-02	-3.46	cholesterol homeostasis	biological process	GO:0042632	101	2	18204	50	APOA1,RORA
3.142e-02	-3.46	regulation of glucose metabolic process	biological process	GO:0010906	101	2	18204	50	PRKN,RORA
3.142e-02	-3.46	actin filament-based movement	biological process	GO:0030048	101	2	18204	50	QKI,GJA1
3.156e-02	-3.46	MIP	prosite domains	PS00221	10	1	12186	39	AQP4
3.165e-02	-3.45	NOC2L (NOC2 like nucleolar associated transcriptional repressor)	protein interactions	26155	274	3	19454	49	FKBP5,FARP1,FGFR3
3.177e-02	-3.45	IGF2BP1 (insulin like growth factor 2 mRNA binding protein 1)	protein interactions	10642	477	4	19454	49	PRKN,SOX5,MSI2,QKI
3.188e-02	-3.45	HYPK (huntingtin interacting protein K)	protein interactions	25764	111	2	19454	49	APOA1,QKI
3.193e-02	-3.44	MAD_homology1_Dwarfin-type	interpro domains	IPR003619	12	1	18521	50	NFIA
3.198e-02	-3.44	USP15 (ubiquitin specific peptidase 15)	protein interactions	9958	478	4	19454	49	FKBP5,APOA1,GRK5,PRKN
3.199e-02	-3.44	sterol homeostasis	biological process	GO:0055092	102	2	18204	50	APOA1,RORA
3.213e-02	-3.44	SRPK2 (SRSF protein kinase 2)	protein interactions	6733	708	5	19454	49	PRKN,FGFR3,SLC39A12,MSI2,TNS3
3.216e-02	-3.44	SH2	pfam domains	PF00017	100	2	17795	50	TNS3,BCAR3
3.220e-02	-3.44	central_nervous_system-brain-glioma-oligodendroglioma_Grade_III	COSMIC cancer mutations	central_nervous_system-brain-glioma-oligodendroglioma_Grade_III	249	3	16828	47	FGFR3,SLC39A12,PTPRZ1
3.226e-02	-3.43	CREB3L4 (cAMP responsive element binding protein 3 like 4)	protein interactions	148327	13	1	19454	49	PRKN
3.226e-02	-3.43	PSD2 (pleckstrin and Sec7 domain containing 2)	protein interactions	84249	13	1	19454	49	FARP1
3.226e-02	-3.43	CACNB4 (calcium voltage-gated channel auxiliary subunit beta 4)	protein interactions	785	13	1	19454	49	PTN
3.226e-02	-3.43	PRRX1 (paired related homeobox 1)	protein interactions	5396	13	1	19454	49	FKBP5
3.226e-02	-3.43	CAPN11 (calpain 11)	protein interactions	11131	13	1	19454	49	PRKN
3.226e-02	-3.43	TUBA3D (tubulin alpha 3d)	protein interactions	113457	13	1	19454	49	PRKN
3.226e-02	-3.43	RAB3C (RAB3C, member RAS oncogene family)	protein interactions	115827	13	1	19454	49	PRKN
3.226e-02	-3.43	DNTT (DNA nucleotidylexotransferase)	protein interactions	1791	13	1	19454	49	APOA1
3.226e-02	-3.43	IL23R (interleukin 23 receptor)	protein interactions	149233	13	1	19454	49	PRKN
3.226e-02	-3.43	LRRC4B (leucine rich repeat containing 4B)	protein interactions	94030	13	1	19454	49	PRKN
3.226e-02	-3.43	NSUN6 (NOP2/Sun RNA methyltransferase 6)	protein interactions	221078	13	1	19454	49	PRKN
3.226e-02	-3.43	CD40LG (CD40 ligand)	protein interactions	959	13	1	19454	49	APOA1
3.226e-02	-3.43	ACSS2 (acyl-CoA synthetase short chain family member 2)	protein interactions	55902	13	1	19454	49	PRKN
3.226e-02	-3.43	SLC4A4 (solute carrier family 4 member 4)	protein interactions	8671	13	1	19454	49	PRKN
3.226e-02	-3.43	CD300C (CD300c molecule)	protein interactions	10871	13	1	19454	49	UNC93A
3.226e-02	-3.43	TAS1R3 (taste 1 receptor member 3)	protein interactions	83756	13	1	19454	49	GJA1
3.226e-02	-3.43	ANKEF1 (ankyrin repeat and EF-hand domain containing 1)	protein interactions	63926	13	1	19454	49	PRKN
3.226e-02	-3.43	Rbm47 (RNA binding motif protein 47)	protein interactions	245945	13	1	19454	49	QKI
3.226e-02	-3.43	ALDH8A1 (aldehyde dehydrogenase 8 family member A1)	protein interactions	64577	13	1	19454	49	PRKN
3.226e-02	-3.43	MOB3A (MOB kinase activator 3A)	protein interactions	126308	13	1	19454	49	PRKN
3.226e-02	-3.43	NCAN (neurocan)	protein interactions	1463	13	1	19454	49	PTN
3.226e-02	-3.43	CABP1 (calcium binding protein 1)	protein interactions	9478	13	1	19454	49	GRK5
3.226e-02	-3.43	OTOA (otoancorin)	protein interactions	146183	13	1	19454	49	PRKN
3.226e-02	-3.43	NOL4L (nucleolar protein 4 like)	protein interactions	140688	13	1	19454	49	CTBP1
3.226e-02	-3.43	TEX15 (testis expressed 15, meiosis and synapsis associated)	protein interactions	56154	13	1	19454	49	PRKN
3.226e-02	-3.43	PCDHA2 (protocadherin alpha 2)	protein interactions	56146	13	1	19454	49	NFIA
3.226e-02	-3.43	PCDHB5 (protocadherin beta 5)	protein interactions	26167	13	1	19454	49	DGKB
3.241e-02	-3.43	ITPR2 (inositol 1,4,5-trisphosphate receptor type 2)	protein interactions	3709	112	2	19454	49	GJA1,PRKN
3.241e-02	-3.43	DTL (denticleless E3 ubiquitin protein ligase homolog)	protein interactions	51514	112	2	19454	49	PREX1,PRKN
3.241e-02	-3.43	P4HA3 (prolyl 4-hydroxylase subunit alpha 3)	protein interactions	283208	112	2	19454	49	TRPS1,PRKN
3.248e-02	-3.43	sulfur amino acid transport	biological process	GO:0000101	12	1	18204	50	SLC1A2
3.248e-02	-3.43	negative regulation of neuroblast proliferation	biological process	GO:0007406	12	1	18204	50	PTN
3.248e-02	-3.43	regulation of intestinal absorption	biological process	GO:1904478	12	1	18204	50	APOA1
3.248e-02	-3.43	regulation of gonadotropin secretion	biological process	GO:0032276	12	1	18204	50	GJA1
3.248e-02	-3.43	oligopeptide transmembrane transport	biological process	GO:0035672	12	1	18204	50	GJA1
3.248e-02	-3.43	negative regulation by host of viral genome replication	biological process	GO:0044828	12	1	18204	50	PRKN
3.248e-02	-3.43	microglia differentiation	biological process	GO:0014004	12	1	18204	50	QKI
3.248e-02	-3.43	negative regulation of protein localization to cell surface	biological process	GO:2000009	12	1	18204	50	GPM6B
3.248e-02	-3.43	positive regulation of protein localization to endosome	biological process	GO:1905668	12	1	18204	50	EGF
3.248e-02	-3.43	endothelin receptor signaling pathway	biological process	GO:0086100	12	1	18204	50	BCAR3
3.248e-02	-3.43	positive regulation of autophagy of mitochondrion in response to mitochondrial depolarization	biological process	GO:1904925	12	1	18204	50	PRKN
3.248e-02	-3.43	regulation of mitochondrial fusion	biological process	GO:0010635	12	1	18204	50	PRKN
3.248e-02	-3.43	auditory behavior	biological process	GO:0031223	12	1	18204	50	SLC1A3
3.250e-02	-3.43	DNA-binding transcription repressor activity, RNA polymerase II-specific	molecular function	GO:0001227	263	3	18094	48	ZBTB20,PRDM16,TRPS1
3.253e-02	-3.43	RBFOX2 (RNA binding fox-1 homolog 2)	protein interactions	23543	277	3	19454	49	PRKN,MSI2,QKI
3.253e-02	-3.43	ACIN1 (apoptotic chromatin condensation inducer 1)	protein interactions	22985	277	3	19454	49	PRKN,GRK5,NFIA
3.254e-02	-3.43	breast-carcinoma	COSMIC cancer mutations	breast-carcinoma	15030	46	16828	47	SLC4A4,FGFRL1,SOX5,SNTB1,TRPS1,GPM6B,DGKB,LRIG1,ASPA,SORCS2,NPAS3,AMOT,SLC6A11,FGFR3,ELOVL2,PREX1,LAMA4,SLC1A2,FHOD3,APOA1,AQP4,QKI,NCKAP5,GJA1,UNC93A,NHSL1,FKBP5,ZBTB20,SLC39A12,EGF,GRK5,CTBP1,PTPRZ1,LPIN2,RFX4,TNS3,GPC5,SLC1A3,USP6NL,PRDM16,PREX2,NFIA,BCAR3,FARP1,PTN,RORA
3.262e-02	-3.42	regulation of cell motility	biological process	GO:2000145	1122	7	18204	50	PREX1,EGF,PLPP3,LAMA4,AMOT,GJA1,PTN
3.264e-02	-3.42	Visual phototransduction	REACTOME pathways	R-HSA-2187338	101	2	10285	29	GPC5,APOA1
3.264e-02	-3.42	Amyloid fiber formation	REACTOME pathways	R-HSA-977225	101	2	10285	29	APOA1,PRKN
3.276e-02	-3.42	steroid binding	molecular function	GO:0005496	107	2	18094	48	RORA,APOA1
3.283e-02	-3.42	TJP2 (tight junction protein 2)	protein interactions	9414	278	3	19454	49	AMOT,GJA1,PRKN
3.284e-02	-3.42	chylomicron	cellular component	GO:0042627	13	1	19108	49	APOA1
3.289e-02	-3.41	positive regulation of RNA metabolic process	biological process	GO:0051254	1912	10	18204	50	PRDM16,NFIA,LPIN2,EGF,QKI,NPAS3,RFX4,PRKN,CTBP1,RORA
3.294e-02	-3.41	AGAP1 (ArfGAP with GTPase domain, ankyrin repeat and PH domain 1)	protein interactions	116987	113	2	19454	49	PRKN,NCKAP5
3.294e-02	-3.41	SATB1 (SATB homeobox 1)	protein interactions	6304	113	2	19454	49	CTBP1,SOX5
3.294e-02	-3.41	GYS1 (glycogen synthase 1)	protein interactions	2997	113	2	19454	49	GRK5,PRKN
3.294e-02	-3.41	LMF2 (lipase maturation factor 2)	protein interactions	91289	113	2	19454	49	GJA1,PRKN
3.298e-02	-3.41	LYN (LYN proto-oncogene, Src family tyrosine kinase)	protein interactions	4067	713	5	19454	49	USP6NL,MSI2,FARP1,SLC1A3,PRKN
3.302e-02	-3.41	skin-face-carcinoma-basal_cell_carcinoma	COSMIC cancer mutations	skin-face-carcinoma-basal_cell_carcinoma	12	1	16828	47	FGFR3
3.302e-02	-3.41	central_nervous_system-fourth_ventricle-glioma-astrocytoma_Grade_I	COSMIC cancer mutations	central_nervous_system-fourth_ventricle-glioma-astrocytoma_Grade_I	12	1	16828	47	QKI
3.302e-02	-3.41	skin-abdomen-malignant_melanoma-nodular	COSMIC cancer mutations	skin-abdomen-malignant_melanoma-nodular	12	1	16828	47	PREX2
3.302e-02	-3.41	cervix-carcinoma-mixed_adenosquamous_carcinoma	COSMIC cancer mutations	cervix-carcinoma-mixed_adenosquamous_carcinoma	12	1	16828	47	FGFR3
3.302e-02	-3.41	skin-benign_melanocytic_nevus	COSMIC cancer mutations	skin-benign_melanocytic_nevus	12	1	16828	47	FGFR3
3.308e-02	-3.41	regulation of neuron projection development	biological process	GO:0010975	443	4	18204	50	PREX1,ADGRB3,PTN,SLC39A12
3.313e-02	-3.41	IRS4 (insulin receptor substrate 4)	protein interactions	8471	279	3	19454	49	FKBP5,PRKN,GJA1
3.315e-02	-3.41	LAMTOR1 (late endosomal/lysosomal adaptor, MAPK and MTOR activator 1)	protein interactions	55004	714	5	19454	49	FARP1,GJA1,SLC1A3,USP6NL,PLPP3
3.315e-02	-3.41	regulation of steroid metabolic process	biological process	GO:0019218	104	2	18204	50	RORA,APOA1
3.315e-02	-3.41	protein polymerization	biological process	GO:0051258	104	2	18204	50	PREX1,PRKN
3.315e-02	-3.41	epithelial cell migration	biological process	GO:0010631	104	2	18204	50	APOA1,AMOT
3.315e-02	-3.41	positive regulation of ubiquitin-dependent protein catabolic process	biological process	GO:2000060	104	2	18204	50	PRKN,EGF
3.321e-02	-3.40	MH1	pfam domains	PF03165	12	1	17795	50	NFIA
3.333e-02	-3.40	Signaling by activated point mutants of FGFR3	REACTOME pathways	R-HSA-1839130	12	1	10285	29	FGFR3
3.333e-02	-3.40	Repression of WNT target genes	REACTOME pathways	R-HSA-4641265	12	1	10285	29	CTBP1
3.333e-02	-3.40	Defective EXT1 causes exostoses 1, TRPS2 and CHDS	REACTOME pathways	R-HSA-3656253	12	1	10285	29	GPC5
3.333e-02	-3.40	Josephin domain DUBs	REACTOME pathways	R-HSA-5689877	12	1	10285	29	PRKN
3.333e-02	-3.40	FGFR3 mutant receptor activation	REACTOME pathways	R-HSA-2033514	12	1	10285	29	FGFR3
3.333e-02	-3.40	Defective EXT2 causes exostoses 2	REACTOME pathways	R-HSA-3656237	12	1	10285	29	GPC5
3.347e-02	-3.40	LAMP3 (lysosomal associated membrane protein 3)	protein interactions	27074	485	4	19454	49	GJA1,ELOVL2,SLC1A3,PLPP3
3.347e-02	-3.40	ATP5MF (ATP synthase membrane subunit f)	protein interactions	9551	114	2	19454	49	PRDM16,PRKN
3.347e-02	-3.40	LSM3 (LSM3 homolog, U6 small nuclear RNA and mRNA degradation associated)	protein interactions	27258	114	2	19454	49	FARP1,QKI
3.347e-02	-3.40	ADSS2 (adenylosuccinate synthase 2)	protein interactions	159	114	2	19454	49	PRKN,CTBP1
3.369e-02	-3.39	PRKACA (protein kinase cAMP-activated catalytic subunit alpha)	protein interactions	5566	486	4	19454	49	FKBP5,SLC4A4,PRKN,SNTB1
3.373e-02	-3.39	positive regulation of protein localization to membrane	biological process	GO:1905477	105	2	18204	50	PRKN,FARP1
3.373e-02	-3.39	biomineral tissue development	biological process	GO:0031214	105	2	18204	50	PTN,FGFR3
3.378e-02	-3.39	pleura-pulmonary_blastoma	COSMIC cancer mutations	pleura-pulmonary_blastoma	648	5	16828	47	TRPS1,FHOD3,FGFRL1,LAMA4,NCKAP5
3.378e-02	-3.39	pulmonary_blastoma	COSMIC cancer mutations	pulmonary_blastoma	648	5	16828	47	LAMA4,FGFRL1,FHOD3,TRPS1,NCKAP5
3.389e-02	-3.38	human chr7q31.32	chromosome location	human chr7q31.32	18	1	26134	50	PTPRZ1
3.394e-02	-3.38	HCO3TRNSPORT	prints domains	PR01231	10	1	5227	18	SLC4A4
3.395e-02	-3.38	high-density lipoprotein particle binding	molecular function	GO:0008035	13	1	18094	48	APOA1
3.395e-02	-3.38	histone H3K9 methyltransferase activity	molecular function	GO:0046974	13	1	18094	48	PRDM16
3.401e-02	-3.38	CAV1 (caveolin 1)	protein interactions	857	719	5	19454	49	USP6NL,PLPP3,GRK5,SLC1A3,GJA1
3.401e-02	-3.38	LZTS1 (leucine zipper tumor suppressor 1)	protein interactions	11178	115	2	19454	49	PRKN,AMOT
3.401e-02	-3.38	TBXT (T-box transcription factor T)	protein interactions	6862	115	2	19454	49	TRPS1,NFIA
3.401e-02	-3.38	DTNA (dystrobrevin alpha)	protein interactions	1837	115	2	19454	49	SNTB1,GJA1
3.419e-02	-3.38	KIF14 (kinesin family member 14)	protein interactions	9928	1803	9	19454	49	FARP1,BCAR3,SOX5,USP6NL,MSI2,AMOT,SORCS2,PRKN,SLC1A3
3.425e-02	-3.37	Endochondral Ossification	WikiPathways	WP474	65	2	5310	24	SOX5,FGFR3
3.425e-02	-3.37	signal transduction	biological process	GO:0007165	4637	19	18204	50	PTN,PREX2,DGKB,AMOT,NFIA,BCAR3,FARP1,EGF,ADGRB3,SLC39A12,SORCS2,RORA,GJA1,APOA1,PREX1,GRK5,FGFRL1,PLPP3,FGFR3
3.432e-02	-3.37	regulation of actin filament bundle assembly	biological process	GO:0032231	106	2	18204	50	PRKN,APOA1
3.434e-02	-3.37	SNX27 (sorting nexin 27)	protein interactions	81609	489	4	19454	49	USP6NL,APOA1,SLC1A3,PRKN
3.438e-02	-3.37	Gastrin-CREB signalling pathway via PKC and MAPK	REACTOME pathways	R-HSA-881907	443	4	10285	29	FGFR3,GRK5,EGF,DGKB
3.440e-02	-3.37	DNA-binding transcription factor activity	molecular function	GO:0003700	1441	8	18094	48	SOX5,TRPS1,RORA,PRDM16,NPAS3,ZBTB20,NFIA,RFX4
3.446e-02	-3.37	DAGKa	smart domains	SM00045	10	1	9717	34	DGKB
3.454e-02	-3.37	FA	interpro domains	IPR014847	13	1	18521	50	FARP1
3.455e-02	-3.37	EHD4 (EH domain containing 4)	protein interactions	30844	116	2	19454	49	CTBP1,PRKN
3.459e-02	-3.36	Gap junction	KEGG pathways	ko04540	88	2	7161	24	EGF,GJA1
3.459e-02	-3.36	Gap junction	KEGG pathways	hsa04540	88	2	7161	24	EGF,GJA1
3.466e-02	-3.36	PKD	prosite domains	PS50093	11	1	12186	39	SORCS2
3.466e-02	-3.36	GATA_ZN_FINGER_2	prosite domains	PS50114	11	1	12186	39	TRPS1
3.466e-02	-3.36	GBD_FH3	prosite domains	PS51232	11	1	12186	39	FHOD3
3.470e-02	-3.36	ACSM3 (acyl-CoA synthetase medium chain family member 3)	protein interactions	6296	14	1	19454	49	PRKN
3.470e-02	-3.36	DNAJC27 (DnaJ heat shock protein family (Hsp40) member C27)	protein interactions	51277	14	1	19454	49	FKBP5
3.470e-02	-3.36	CYP2W1 (cytochrome P450 family 2 subfamily W member 1)	protein interactions	54905	14	1	19454	49	PRKN
3.470e-02	-3.36	HOXC6 (homeobox C6)	protein interactions	3223	14	1	19454	49	BCAR3
3.470e-02	-3.36	TTLL7 (tubulin tyrosine ligase like 7)	protein interactions	79739	14	1	19454	49	PRKN
3.470e-02	-3.36	PGS1 (phosphatidylglycerophosphate synthase 1)	protein interactions	9489	14	1	19454	49	PRKN
3.470e-02	-3.36	ZNF628 (zinc finger protein 628)	protein interactions	89887	14	1	19454	49	PRKN
3.470e-02	-3.36	MEIOC (meiosis specific with coiled-coil domain)	protein interactions	284071	14	1	19454	49	PRKN
3.470e-02	-3.36	MAOA (monoamine oxidase A)	protein interactions	4128	14	1	19454	49	PRKN
3.470e-02	-3.36	FGF7 (fibroblast growth factor 7)	protein interactions	2252	14	1	19454	49	FGFR3
3.470e-02	-3.36	CFAP58 (cilia and flagella associated protein 58)	protein interactions	159686	14	1	19454	49	PRKN
3.470e-02	-3.36	GRID2 (glutamate ionotropic receptor delta type subunit 2)	protein interactions	2895	14	1	19454	49	PRKN
3.470e-02	-3.36	ZNF625 (zinc finger protein 625)	protein interactions	90589	14	1	19454	49	PRKN
3.470e-02	-3.36	RGS13 (regulator of G protein signaling 13)	protein interactions	6003	14	1	19454	49	PRKN
3.470e-02	-3.36	ROBO3 (roundabout guidance receptor 3)	protein interactions	64221	14	1	19454	49	APOA1
3.470e-02	-3.36	Plekhg5 (pleckstrin homology domain containing, family G (with RhoGef domain) member 5)	protein interactions	269608	14	1	19454	49	AMOT
3.470e-02	-3.36	DACT2 (dishevelled binding antagonist of beta catenin 2)	protein interactions	168002	14	1	19454	49	ZBTB20
3.470e-02	-3.36	PLPP1 (phospholipid phosphatase 1)	protein interactions	8611	14	1	19454	49	PLPP3
3.470e-02	-3.36	SCRN3 (secernin 3)	protein interactions	79634	14	1	19454	49	PRKN
3.470e-02	-3.36	SLC1A2 (solute carrier family 1 member 2)	protein interactions	6506	14	1	19454	49	SLC1A2
3.470e-02	-3.36	CHGA (chromogranin A)	protein interactions	1113	14	1	19454	49	PRKN
3.470e-02	-3.36	SPTBN5 (spectrin beta, non-erythrocytic 5)	protein interactions	51332	14	1	19454	49	PRKN
3.470e-02	-3.36	ADAP2 (ArfGAP with dual PH domains 2)	protein interactions	55803	14	1	19454	49	PRKN
3.470e-02	-3.36	UAP1L1 (UDP-N-acetylglucosamine pyrophosphorylase 1 like 1)	protein interactions	91373	14	1	19454	49	PRKN
3.470e-02	-3.36	Cstf2t (cleavage stimulation factor, 3' pre-RNA subunit 2, tau)	protein interactions	83410	14	1	19454	49	CTBP1
3.470e-02	-3.36	NSUN5P2 (NSUN5 pseudogene 2)	protein interactions	260294	14	1	19454	49	PRKN
3.473e-02	-3.36	upper_leg	COSMIC cancer mutations	upper_leg	880	6	16828	47	AMOT,LRIG1,PREX2,NFIA,FGFR3,SLC6A11
3.485e-02	-3.36	regulation of anatomical structure morphogenesis	biological process	GO:0022603	894	6	18204	50	EGF,ADGRB3,SLC39A12,AMOT,GJA1,PRKN
3.492e-02	-3.35	epithelium migration	biological process	GO:0090132	107	2	18204	50	AMOT,APOA1
3.496e-02	-3.35	SART3 (spliceosome associated factor 3, U4/U6 recycling protein)	protein interactions	9733	285	3	19454	49	PRKN,AMOT,CTBP1
3.496e-02	-3.35	MAVS (mitochondrial antiviral signaling protein)	protein interactions	57506	285	3	19454	49	FGFR3,PRKN,SLC39A12
3.500e-02	-3.35	SH2	interpro domains	IPR000980	109	2	18521	50	BCAR3,TNS3
3.505e-02	-3.35	transcription coactivator activity	molecular function	GO:0003713	271	3	18094	48	PRDM16,CTBP1,LPIN2
3.508e-02	-3.35	regulation of catalytic activity	biological process	GO:0050790	1395	8	18204	50	PREX2,APOA1,USP6NL,PRKN,PREX1,BCAR3,EGF,FGFR3
3.510e-02	-3.35	HSP90AB4P (heat shock protein 90 alpha family class B member 4, pseudogene)	protein interactions	664618	117	2	19454	49	PRKN,FKBP5
3.514e-02	-3.35	glial cell fate commitment	biological process	GO:0021781	13	1	18204	50	NFIA
3.514e-02	-3.35	regulation of protein localization to endosome	biological process	GO:1905666	13	1	18204	50	EGF
3.514e-02	-3.35	regulation of autophagy of mitochondrion in response to mitochondrial depolarization	biological process	GO:1904923	13	1	18204	50	PRKN
3.514e-02	-3.35	negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway	biological process	GO:1903377	13	1	18204	50	PRKN
3.514e-02	-3.35	positive regulation of mitophagy	biological process	GO:1901526	13	1	18204	50	PRKN
3.514e-02	-3.35	heterochromatin organization	biological process	GO:0070828	13	1	18204	50	PRDM16
3.514e-02	-3.35	positive regulation of neuron projection regeneration	biological process	GO:0070572	13	1	18204	50	PTN
3.514e-02	-3.35	positive regulation of axon regeneration	biological process	GO:0048680	13	1	18204	50	PTN
3.514e-02	-3.35	cerebellar Purkinje cell differentiation	biological process	GO:0021702	13	1	18204	50	RORA
3.514e-02	-3.35	phospholipid efflux	biological process	GO:0033700	13	1	18204	50	APOA1
3.514e-02	-3.35	very long-chain fatty acid biosynthetic process	biological process	GO:0042761	13	1	18204	50	ELOVL2
3.514e-02	-3.35	T-helper 17 cell differentiation	biological process	GO:0072539	13	1	18204	50	RORA
3.527e-02	-3.34	FNDC3A (fibronectin type III domain containing 3A)	protein interactions	22862	286	3	19454	49	GJA1,SORCS2,AMOT
3.527e-02	-3.34	EGF/EGFR Signaling Pathway	WikiPathways	WP437	162	3	5310	24	EGF,USP6NL,GJA1
3.532e-02	-3.34	dopaminergic synapse	cellular component	GO:0098691	14	1	19108	49	PRKN
3.532e-02	-3.34	extrinsic component of synaptic membrane	cellular component	GO:0099243	14	1	19108	49	FARP1
3.533e-02	-3.34	regulation of plasma membrane bounded cell projection organization	biological process	GO:0120035	666	5	18204	50	PTN,SLC39A12,ADGRB3,PREX1,USP6NL
3.538e-02	-3.34	DNA-binding transcription repressor activity	molecular function	GO:0001217	272	3	18094	48	ZBTB20,TRPS1,PRDM16
3.545e-02	-3.34	NEDD4 (NEDD4 E3 ubiquitin protein ligase)	protein interactions	4734	494	4	19454	49	AMOT,GJA1,PRKN,FGFR3
3.551e-02	-3.34	tissue remodeling	biological process	GO:0048771	108	2	18204	50	PTN,GJA1
3.561e-02	-3.34	FTO Obesity Variant Mechanism	WikiPathways	WP3407	8	1	5310	24	PRDM16
3.565e-02	-3.33	SIPA1L2 (signal induced proliferation associated 1 like 2)	protein interactions	57568	118	2	19454	49	AMOT,GJA1
3.565e-02	-3.33	DNAAF10 (dynein axonemal assembly factor 10)	protein interactions	116143	118	2	19454	49	FKBP5,FGFR3
3.572e-02	-3.33	skin-shoulder-malignant_melanoma-nodular	COSMIC cancer mutations	skin-shoulder-malignant_melanoma-nodular	13	1	16828	47	PREX2
3.572e-02	-3.33	cervix-carcinoma-adenocarcinoma	COSMIC cancer mutations	cervix-carcinoma-adenocarcinoma	13	1	16828	47	FGFR3
3.572e-02	-3.33	central_nervous_system-hypothalamus-glioma-astrocytoma_Grade_I	COSMIC cancer mutations	central_nervous_system-hypothalamus-glioma-astrocytoma_Grade_I	13	1	16828	47	QKI
3.572e-02	-3.33	Brenner_tumour	COSMIC cancer mutations	Brenner_tumour	13	1	16828	47	FGFR3
3.572e-02	-3.33	endometrium-ovary-endometriosis	COSMIC cancer mutations	endometrium-ovary-endometriosis	13	1	16828	47	FGFR3
3.572e-02	-3.33	skin-back-carcinoma-basal_cell_carcinoma	COSMIC cancer mutations	skin-back-carcinoma-basal_cell_carcinoma	13	1	16828	47	FGFR3
3.572e-02	-3.33	skin-scalp-malignant_melanoma-nodular	COSMIC cancer mutations	skin-scalp-malignant_melanoma-nodular	13	1	16828	47	PREX2
3.574e-02	-3.33	human chr6q24.1	chromosome location	human chr6q24.1	19	1	26134	50	NHSL1
3.589e-02	-3.33	VASP (vasodilator stimulated phosphoprotein)	protein interactions	7408	288	3	19454	49	AMOT,PRKN,NHSL1
3.593e-02	-3.33	FA	pfam domains	PF08736	13	1	17795	50	FARP1
3.593e-02	-3.33	Ldl_recept_b	pfam domains	PF00058	13	1	17795	50	EGF
3.593e-02	-3.33	positive regulation of DNA-templated transcription	biological process	GO:0045893	1667	9	18204	50	PRDM16,NFIA,NPAS3,EGF,LPIN2,RFX4,RORA,PRKN,CTBP1
3.606e-02	-3.32	Phospholipase C-mediated cascade; FGFR3	REACTOME pathways	R-HSA-5654227	13	1	10285	29	FGFR3
3.606e-02	-3.32	ERBB2 Activates PTK6 Signaling	REACTOME pathways	R-HSA-8847993	13	1	10285	29	EGF
3.606e-02	-3.32	FGFR3c ligand binding and activation	REACTOME pathways	R-HSA-190372	13	1	10285	29	FGFR3
3.606e-02	-3.32	FGFRL1 modulation of FGFR1 signaling	REACTOME pathways	R-HSA-5658623	13	1	10285	29	FGFRL1
3.606e-02	-3.32	Passive transport by Aquaporins	REACTOME pathways	R-HSA-432047	13	1	10285	29	AQP4
3.606e-02	-3.32	Scavenging of heme from plasma	REACTOME pathways	R-HSA-2168880	13	1	10285	29	APOA1
3.606e-02	-3.32	FGFR3 ligand binding and activation	REACTOME pathways	R-HSA-190239	13	1	10285	29	FGFR3
3.612e-02	-3.32	long-chain fatty acid metabolic process	biological process	GO:0001676	109	2	18204	50	QKI,ELOVL2
3.620e-02	-3.32	regulation of canonical Wnt signaling pathway	biological process	GO:0060828	265	3	18204	50	EGF,PRKN,GPC5
3.620e-02	-3.32	OXCT1 (3-oxoacid CoA-transferase 1)	protein interactions	5019	119	2	19454	49	ADGRB3,PRKN
3.629e-02	-3.32	positive regulation of RNA biosynthetic process	biological process	GO:1902680	1670	9	18204	50	NFIA,PRDM16,EGF,LPIN2,NPAS3,RFX4,PRKN,CTBP1,RORA
3.656e-02	-3.31	acute_lymphoblastic_leukaemia	COSMIC cancer mutations	acute_lymphoblastic_leukaemia	2197	11	16828	47	CTBP1,PTPRZ1,GRK5,SLC4A4,FGFR3,FGFRL1,SOX5,FHOD3,TRPS1,PREX2,NFIA
3.658e-02	-3.31	bone-scapula-Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour	COSMIC cancer mutations	bone-scapula-Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour	108	2	16828	47	FGFR3,SNTB1
3.668e-02	-3.31	PTEN (phosphatase and tensin homolog)	protein interactions	5728	734	5	19454	49	CTBP1,FKBP5,AMOT,PLPP3,PRKN
3.670e-02	-3.30	positive regulation of cell development	biological process	GO:0010720	458	4	18204	50	QKI,PTPRZ1,PTN,ASPA
3.672e-02	-3.30	positive regulation of binding	biological process	GO:0051099	110	2	18204	50	EGF,PRKN
3.672e-02	-3.30	positive regulation of canonical Wnt signaling pathway	biological process	GO:0090263	110	2	18204	50	GPC5,EGF
3.675e-02	-3.30	urinary_tract-bladder-carcinoma	COSMIC cancer mutations	urinary_tract-bladder-carcinoma	14050	44	16828	47	DGKB,LRIG1,GPM6B,TRPS1,GRK5,EGF,SNTB1,SOX5,FGFRL1,SLC39A12,SLC4A4,SLC1A3,USP6NL,TNS3,GPC5,SLC6A11,LPIN2,RFX4,AMOT,CTBP1,NPAS3,PTPRZ1,SORCS2,MSI2,ASPA,PREX2,NFIA,FHOD3,SLC1A2,PREX1,PRDM16,LAMA4,FGFR3,ELOVL2,PTN,ZBTB20,RORA,FKBP5,FARP1,UNC93A,BCAR3,GJA1,QKI,NCKAP5
3.676e-02	-3.30	LPCAT1 (lysophosphatidylcholine acyltransferase 1)	protein interactions	79888	120	2	19454	49	PRKN,FGFR3
3.676e-02	-3.30	ACSL4 (acyl-CoA synthetase long chain family member 4)	protein interactions	2182	120	2	19454	49	PRKN,SLC39A12
3.676e-02	-3.30	TOMM70 (translocase of outer mitochondrial membrane 70)	protein interactions	9868	120	2	19454	49	FKBP5,PRKN
3.676e-02	-3.30	UBE2S (ubiquitin conjugating enzyme E2 S)	protein interactions	27338	120	2	19454	49	USP6NL,PRKN
3.676e-02	-3.30	FHL1 (four and a half LIM domains 1)	protein interactions	2273	120	2	19454	49	LAMA4,PRKN
3.676e-02	-3.30	LIMD1 (LIM domain containing 1)	protein interactions	8994	120	2	19454	49	PRKN,AMOT
3.677e-02	-3.30	transcription coregulator binding	molecular function	GO:0001221	114	2	18094	48	CTBP1,RORA
3.683e-02	-3.30	GOPC (golgi associated PDZ and coiled-coil motif containing)	protein interactions	57120	291	3	19454	49	GJA1,FGFR3,PRKN
3.684e-02	-3.30	positive regulation of cell differentiation	biological process	GO:0045597	906	6	18204	50	PTPRZ1,QKI,ASPA,PTN,SOX5,GJA1
3.685e-02	-3.30	thyroid	COSMIC cancer mutations	thyroid	9867	34	16828	47	SLC6A11,TNS3,GPC5,CTBP1,PTPRZ1,AMOT,ASPA,SORCS2,LRIG1,TRPS1,GPM6B,SNTB1,GRK5,SLC4A4,SOX5,FGFRL1,FARP1,PTN,FKBP5,RORA,UNC93A,NHSL1,NCKAP5,BCAR3,AQP4,FHOD3,PREX2,NFIA,SLC1A2,FGFR3,ELOVL2,PRDM16,PREX1,LAMA4
3.688e-02	-3.30	plasma membrane bounded cell projection organization	biological process	GO:0120036	1152	7	18204	50	GPM6B,PTPRZ1,FARP1,RFX4,PREX2,PTN,SLC39A12
3.695e-02	-3.30	synaptic signaling	biological process	GO:0099536	459	4	18204	50	SLC1A3,SLC1A2,PRKN,FARP1
3.695e-02	-3.30	small molecule biosynthetic process	biological process	GO:0044283	459	4	18204	50	SLC1A3,QKI,ELOVL2,APOA1
3.714e-02	-3.29	FGF9 (fibroblast growth factor 9)	protein interactions	2254	15	1	19454	49	FGFR3
3.714e-02	-3.29	RAB40AL (RAB40A like)	protein interactions	282808	15	1	19454	49	PRKN
3.714e-02	-3.29	GCK (glucokinase)	protein interactions	2645	15	1	19454	49	PRKN
3.714e-02	-3.29	MTRR (5-methyltetrahydrofolate-homocysteine methyltransferase reductase)	protein interactions	4552	15	1	19454	49	PRKN
3.714e-02	-3.29	ADRA1B (adrenoceptor alpha 1B)	protein interactions	147	15	1	19454	49	PRKN
3.714e-02	-3.29	Cenpf (centromere protein F)	protein interactions	108000	15	1	19454	49	USP6NL
3.714e-02	-3.29	SEMA3F (semaphorin 3F)	protein interactions	6405	15	1	19454	49	PRKN
3.714e-02	-3.29	DOP1A (DOP1 leucine zipper like protein A)	protein interactions	23033	15	1	19454	49	PRKN
3.714e-02	-3.29	FN3K (fructosamine 3 kinase)	protein interactions	64122	15	1	19454	49	PRKN
3.714e-02	-3.29	DTWD1 (DTW domain containing 1)	protein interactions	56986	15	1	19454	49	APOA1
3.714e-02	-3.29	RGS9 (regulator of G protein signaling 9)	protein interactions	8787	15	1	19454	49	PRKN
3.714e-02	-3.29	ZNF616 (zinc finger protein 616)	protein interactions	90317	15	1	19454	49	PRKN
3.714e-02	-3.29	ASIC2 (acid sensing ion channel subunit 2)	protein interactions	40	15	1	19454	49	PRKN
3.714e-02	-3.29	ACTRT1 (actin related protein T1)	protein interactions	139741	15	1	19454	49	PRKN
3.714e-02	-3.29	POFUT2 (protein O-fucosyltransferase 2)	protein interactions	23275	15	1	19454	49	PRKN
3.715e-02	-3.29	IBR_dom	interpro domains	IPR002867	14	1	18521	50	PRKN
3.715e-02	-3.29	Aquaporin-like	interpro domains	IPR023271	14	1	18521	50	AQP4
3.715e-02	-3.29	MIP	interpro domains	IPR000425	14	1	18521	50	AQP4
3.715e-02	-3.29	LDLR_classB_rpt	interpro domains	IPR000033	14	1	18521	50	EGF
3.715e-02	-3.29	TRIAD_supradom	interpro domains	IPR044066	14	1	18521	50	PRKN
3.715e-02	-3.29	ZIP	interpro domains	IPR003689	14	1	18521	50	SLC39A12
3.715e-02	-3.29	SENP3 (SUMO specific peptidase 3)	protein interactions	26168	292	3	19454	49	ZBTB20,PRDM16,PRKN
3.715e-02	-3.29	HNRNPH2 (heterogeneous nuclear ribonucleoprotein H2)	protein interactions	3188	292	3	19454	49	PRKN,MSI2,QKI
3.720e-02	-3.29	negative regulation of transport	biological process	GO:0051051	460	4	18204	50	GJA1,PRKN,EGF,GPM6B
3.724e-02	-3.29	regulation of signal transduction	biological process	GO:0009966	3114	14	18204	50	PRDM16,GRK5,FGFR3,PLPP3,PREX1,PRKN,RORA,APOA1,GJA1,GPC5,BCAR3,EGF,PREX2,AMOT
3.732e-02	-3.29	MED15 (mediator complex subunit 15)	protein interactions	51586	121	2	19454	49	NFIA,QKI
3.732e-02	-3.29	POLR3B (RNA polymerase III subunit B)	protein interactions	55703	121	2	19454	49	FKBP5,PRKN
3.732e-02	-3.29	GAS8 (growth arrest specific 8)	protein interactions	2622	121	2	19454	49	PRKN,BCAR3
3.738e-02	-3.29	SH2_dom_sf	interpro domains	IPR036860	113	2	18521	50	TNS3,BCAR3
3.759e-02	-3.28	regulation of actin filament organization	biological process	GO:0110053	269	3	18204	50	PRKN,PREX1,APOA1
3.759e-02	-3.28	human chr18q12.2	chromosome location	human chr18q12.2	20	1	26134	50	FHOD3
3.765e-02	-3.28	SH2 domain	gene3d domains	3.30.505.10	111	2	14470	40	BCAR3,TNS3
3.779e-02	-3.28	glutathione biosynthetic process	biological process	GO:0006750	14	1	18204	50	SLC1A2
3.779e-02	-3.28	mechanosensory behavior	biological process	GO:0007638	14	1	18204	50	SLC1A3
3.779e-02	-3.28	atrial cardiac muscle cell to AV node cell signaling	biological process	GO:0086026	14	1	18204	50	GJA1
3.779e-02	-3.28	neuron remodeling	biological process	GO:0016322	14	1	18204	50	ADGRB3
3.779e-02	-3.28	fatty acid elongation	biological process	GO:0030497	14	1	18204	50	ELOVL2
3.779e-02	-3.28	oligopeptide transport	biological process	GO:0006857	14	1	18204	50	GJA1
3.779e-02	-3.28	atrial cardiac muscle cell action potential	biological process	GO:0086014	14	1	18204	50	GJA1
3.779e-02	-3.28	positive regulation of tumor necrosis factor-mediated signaling pathway	biological process	GO:1903265	14	1	18204	50	PRKN
3.779e-02	-3.28	negative regulation of long-term synaptic potentiation	biological process	GO:1900272	14	1	18204	50	PTN
3.779e-02	-3.28	negative regulation of cell adhesion molecule production	biological process	GO:0060354	14	1	18204	50	APOA1
3.779e-02	-3.28	adult heart development	biological process	GO:0007512	14	1	18204	50	GJA1
3.779e-02	-3.28	sodium ion export across plasma membrane	biological process	GO:0036376	14	1	18204	50	SLC4A4
3.779e-02	-3.28	positive regulation of phospholipid transport	biological process	GO:2001140	14	1	18204	50	APOA1
3.779e-02	-3.28	cerebrospinal fluid circulation	biological process	GO:0090660	14	1	18204	50	AQP4
3.779e-02	-3.28	MMS19 (MMS19 homolog, cytosolic iron-sulfur assembly component)	protein interactions	64210	294	3	19454	49	PRKN,FGFR3,GRK5
3.779e-02	-3.28	IGF2R (insulin like growth factor 2 receptor)	protein interactions	3482	294	3	19454	49	CTBP1,PRKN,GJA1
3.780e-02	-3.28	axolemma	cellular component	GO:0030673	15	1	19108	49	SLC1A2
3.780e-02	-3.28	low-density lipoprotein particle	cellular component	GO:0034362	15	1	19108	49	APOA1
3.788e-02	-3.27	OGA (O-GlcNAcase)	protein interactions	10724	122	2	19454	49	FKBP5,PRKN
3.788e-02	-3.27	MED31 (mediator complex subunit 31)	protein interactions	51003	122	2	19454	49	LAMA4,QKI
3.788e-02	-3.27	RTCA (RNA 3'-terminal phosphate cyclase)	protein interactions	8634	122	2	19454	49	AMOT,PRKN
3.803e-02	-3.27	-	gene3d domains	1.20.120.1750	14	1	14470	40	PRKN
3.803e-02	-3.27	-	gene3d domains	2.60.200.40	14	1	14470	40	DGKB
3.803e-02	-3.27	Glycerol uptake facilitator protein	gene3d domains	1.20.1080.10	14	1	14470	40	AQP4
3.821e-02	-3.26	cellular lipid metabolic process	biological process	GO:0044255	914	6	18204	50	PLPP3,QKI,LPIN2,ELOVL2,APOA1,DGKB
3.822e-02	-3.26	cellular response to organic cyclic compound	biological process	GO:0071407	464	4	18204	50	SLC1A2,SLC1A3,RORA,PRKN
3.829e-02	-3.26	carboxylic acid biosynthetic process	biological process	GO:0046394	271	3	18204	50	QKI,ELOVL2,SLC1A3
3.838e-02	-3.26	response to organonitrogen compound	biological process	GO:0010243	915	6	18204	50	SLC1A3,GJA1,PRKN,SLC1A2,BCAR3,LPIN2
3.841e-02	-3.26	small_round_cell_tumour	COSMIC cancer mutations	small_round_cell_tumour	14	1	16828	47	FGFR3
3.841e-02	-3.26	soft_tissue-small_round_cell_tumour	COSMIC cancer mutations	soft_tissue-small_round_cell_tumour	14	1	16828	47	FGFR3
3.841e-02	-3.26	endometriosis	COSMIC cancer mutations	endometriosis	14	1	16828	47	FGFR3
3.841e-02	-3.26	in_situ_neoplasm	COSMIC cancer mutations	in_situ_neoplasm	14	1	16828	47	FGFR3
3.841e-02	-3.26	urinary_tract-renal_pelvis-carcinoma-transitional_cell_carcinoma	COSMIC cancer mutations	urinary_tract-renal_pelvis-carcinoma-transitional_cell_carcinoma	14	1	16828	47	FGFR3
3.843e-02	-3.26	RHOU (ras homolog family member U)	protein interactions	58480	507	4	19454	49	FARP1,GJA1,USP6NL,TNS3
3.844e-02	-3.26	NCAPH (non-SMC condensin I complex subunit H)	protein interactions	23397	296	3	19454	49	PRDM16,FGFR3,PRKN
3.844e-02	-3.26	PTK2 (protein tyrosine kinase 2)	protein interactions	5747	296	3	19454	49	TNS3,FKBP5,PRKN
3.844e-02	-3.26	PAX7 (paired box 7)	protein interactions	5081	123	2	19454	49	TRPS1,NFIA
3.844e-02	-3.26	UBASH3A (ubiquitin associated and SH3 domain containing A)	protein interactions	53347	123	2	19454	49	PRKN,BCAR3
3.844e-02	-3.26	NAMPT (nicotinamide phosphoribosyltransferase)	protein interactions	10135	123	2	19454	49	PRKN,FGFR3
3.844e-02	-3.26	ETF1 (eukaryotic translation termination factor 1)	protein interactions	2107	123	2	19454	49	PRKN,FGFR3
3.844e-02	-3.26	ACOT1 (acyl-CoA thioesterase 1)	protein interactions	641371	123	2	19454	49	PRKN,FGFR3
3.850e-02	-3.26	bile_duct	COSMIC cancer mutations	bile_duct	15095	46	16828	47	SLC1A3,USP6NL,TNS3,GPC5,RFX4,LPIN2,CTBP1,PTPRZ1,MSI2,GRK5,EGF,SLC39A12,PTN,RORA,FARP1,BCAR3,PREX2,NFIA,PRDM16,SLC6A11,AMOT,NPAS3,SORCS2,ASPA,DGKB,LRIG1,GPM6B,TRPS1,SNTB1,FGFRL1,SOX5,SLC4A4,ZBTB20,FKBP5,NHSL1,UNC93A,GJA1,QKI,AQP4,APOA1,FHOD3,SLC1A2,PREX1,LAMA4,FGFR3,ELOVL2
3.850e-02	-3.26	biliary_tract-bile_duct-carcinoma-adenocarcinoma	COSMIC cancer mutations	biliary_tract-bile_duct-carcinoma-adenocarcinoma	15095	46	16828	47	PREX1,LAMA4,FGFR3,ELOVL2,SLC1A2,FHOD3,APOA1,AQP4,GJA1,QKI,NHSL1,UNC93A,ZBTB20,FKBP5,FGFRL1,SOX5,SLC4A4,SNTB1,GPM6B,TRPS1,DGKB,LRIG1,SORCS2,ASPA,AMOT,NPAS3,SLC6A11,PRDM16,PREX2,NFIA,BCAR3,PTN,RORA,FARP1,SLC39A12,GRK5,EGF,MSI2,RFX4,LPIN2,CTBP1,PTPRZ1,TNS3,GPC5,SLC1A3,USP6NL
3.856e-02	-3.26	tissue migration	biological process	GO:0090130	113	2	18204	50	AMOT,APOA1
3.864e-02	-3.25	Zip	pfam domains	PF02535	14	1	17795	50	SLC39A12
3.864e-02	-3.25	MIP	pfam domains	PF00230	14	1	17795	50	AQP4
3.864e-02	-3.25	GATA	pfam domains	PF00320	14	1	17795	50	TRPS1
3.868e-02	-3.25	regulation of locomotion	biological process	GO:0040012	1164	7	18204	50	PLPP3,EGF,PREX1,LAMA4,AMOT,GJA1,PTN
3.873e-02	-3.25	regulation of protein phosphorylation	biological process	GO:0001932	917	6	18204	50	APOA1,PRKN,PLPP3,EGF,FGFR3,BCAR3
3.873e-02	-3.25	regulation of cell projection organization	biological process	GO:0031344	683	5	18204	50	SLC39A12,PTN,USP6NL,ADGRB3,PREX1
3.878e-02	-3.25	Synthesis of PE	REACTOME pathways	R-HSA-1483213	14	1	10285	29	LPIN2
3.900e-02	-3.24	vascular process in circulatory system	biological process	GO:0003018	273	3	18204	50	SLC1A2,SLC1A3,SLC4A4
3.901e-02	-3.24	HMGCR (3-hydroxy-3-methylglutaryl-CoA reductase)	protein interactions	3156	124	2	19454	49	CTBP1,SORCS2
3.908e-02	-3.24	monocarboxylate:sodium symporter activity	molecular function	GO:0140161	15	1	18094	48	SLC6A11
3.908e-02	-3.24	efflux transmembrane transporter activity	molecular function	GO:0015562	15	1	18094	48	GJA1
3.909e-02	-3.24	ALDH3A2 (aldehyde dehydrogenase 3 family member A2)	protein interactions	224	298	3	19454	49	GJA1,FGFR3,PRKN
3.936e-02	-3.24	organic acid biosynthetic process	biological process	GO:0016053	274	3	18204	50	QKI,ELOVL2,SLC1A3
3.942e-02	-3.23	MRPS31 (mitochondrial ribosomal protein S31)	protein interactions	10240	299	3	19454	49	AMOT,PRKN,FGFR3
3.942e-02	-3.23	MRPS34 (mitochondrial ribosomal protein S34)	protein interactions	65993	299	3	19454	49	SOX5,PRKN,FGFR3
3.943e-02	-3.23	human chr10q26.11	chromosome location	human chr10q26.11	21	1	26134	50	GRK5
3.943e-02	-3.23	human chr13q31.3	chromosome location	human chr13q31.3	21	1	26134	50	GPC5
3.943e-02	-3.23	cell migration	biological process	GO:0016477	921	6	18204	50	GPC5,PTN,AMOT,APOA1,GJA1,PREX1
3.956e-02	-3.23	GDPGP1 (GDP-D-glucose phosphorylase 1)	protein interactions	390637	16	1	19454	49	PRKN
3.956e-02	-3.23	HHV8GK18_gp78 (ORF69)	protein interactions	4961444	16	1	19454	49	CTBP1
3.956e-02	-3.23	NBL1 (NBL1, DAN family BMP antagonist)	protein interactions	4681	16	1	19454	49	LRIG1
3.956e-02	-3.23	PLEKHH2 (pleckstrin homology, MyTH4 and FERM domain containing H2)	protein interactions	130271	16	1	19454	49	PRKN
3.956e-02	-3.23	RHO (rhodopsin)	protein interactions	6010	16	1	19454	49	GRK5
3.956e-02	-3.23	DPH7 (diphthamide biosynthesis 7)	protein interactions	92715	16	1	19454	49	PRKN
3.956e-02	-3.23	TTC39B (tetratricopeptide repeat domain 39B)	protein interactions	158219	16	1	19454	49	PRKN
3.956e-02	-3.23	ZFAND1 (zinc finger AN1-type containing 1)	protein interactions	79752	16	1	19454	49	PRKN
3.956e-02	-3.23	MT1M (metallothionein 1M)	protein interactions	4499	16	1	19454	49	PRKN
3.956e-02	-3.23	CTSK (cathepsin K)	protein interactions	1513	16	1	19454	49	FGFR3
3.956e-02	-3.23	MKKS (MKKS centrosomal shuttling protein)	protein interactions	8195	16	1	19454	49	PTN
3.956e-02	-3.23	MX2 (MX dynamin like GTPase 2)	protein interactions	4600	16	1	19454	49	PRKN
3.956e-02	-3.23	MAML2 (mastermind like transcriptional coactivator 2)	protein interactions	84441	16	1	19454	49	CTBP1
3.956e-02	-3.23	KCNH1 (potassium voltage-gated channel subfamily H member 1)	protein interactions	3756	16	1	19454	49	PRKN
3.956e-02	-3.23	TXNDC2 (thioredoxin domain containing 2)	protein interactions	84203	16	1	19454	49	APOA1
3.956e-02	-3.23	ARHGEF3 (Rho guanine nucleotide exchange factor 3)	protein interactions	50650	16	1	19454	49	PRKN
3.956e-02	-3.23	PIPOX (pipecolic acid and sarcosine oxidase)	protein interactions	51268	16	1	19454	49	FKBP5
3.956e-02	-3.23	TWIST2 (twist family bHLH transcription factor 2)	protein interactions	117581	16	1	19454	49	ZBTB20
3.956e-02	-3.23	F13A1 (coagulation factor XIII A chain)	protein interactions	2162	16	1	19454	49	PRKN
3.956e-02	-3.23	PYROXD1 (pyridine nucleotide-disulphide oxidoreductase domain 1)	protein interactions	79912	16	1	19454	49	PRKN
3.956e-02	-3.23	IL1RL2 (interleukin 1 receptor like 2)	protein interactions	8808	16	1	19454	49	PRKN
3.956e-02	-3.23	SLC35E4 (solute carrier family 35 member E4)	protein interactions	339665	16	1	19454	49	UNC93A
3.958e-02	-3.23	CBLN4 (cerebellin 4 precursor)	protein interactions	140689	125	2	19454	49	PRKN,FGFR3
3.958e-02	-3.23	UACA (uveal autoantigen with coiled-coil domains and ankyrin repeats)	protein interactions	55075	125	2	19454	49	GJA1,PRKN
3.959e-02	-3.23	NAD+ Signalling and Aging	SMPDB pathways	SMP0084271	11	1	1369	5	RORA
3.959e-02	-3.23	Aspartate Metabolism	SMPDB pathways	SMP0000067	11	1	1369	5	ASPA
3.959e-02	-3.23	Canavan Disease	SMPDB pathways	SMP0000175	11	1	1369	5	ASPA
3.959e-02	-3.23	Hypoacetylaspartia	SMPDB pathways	SMP0000192	11	1	1369	5	ASPA
3.961e-02	-3.23	HGS (hepatocyte growth factor-regulated tyrosine kinase substrate)	protein interactions	9146	512	4	19454	49	FGFR3,PRKN,GJA1,LRIG1
3.975e-02	-3.23	Znf_GATA	interpro domains	IPR000679	15	1	18521	50	TRPS1
3.975e-02	-3.23	FH2_Formin_sf	interpro domains	IPR042201	15	1	18521	50	FHOD3
3.975e-02	-3.23	Diacylglycerol_kinase_cat_dom	interpro domains	IPR001206	15	1	18521	50	DGKB
3.975e-02	-3.23	PPIase_FKBP_dom	interpro domains	IPR001179	15	1	18521	50	FKBP5
3.975e-02	-3.23	FH2_Formin	interpro domains	IPR015425	15	1	18521	50	FHOD3
3.981e-02	-3.22	fatty acid biosynthetic process	biological process	GO:0006633	115	2	18204	50	ELOVL2,QKI
4.008e-02	-3.22	transcription cis-regulatory region binding	molecular function	GO:0000976	1485	8	18094	48	RFX4,SOX5,RORA,PRDM16,TRPS1,ZBTB20,NPAS3,NFIA
4.016e-02	-3.21	CDK18 (cyclin dependent kinase 18)	protein interactions	5129	126	2	19454	49	FKBP5,TRPS1
4.016e-02	-3.21	IGKC (immunoglobulin kappa constant)	protein interactions	3514	126	2	19454	49	PRKN,APOA1
4.016e-02	-3.21	IFT74 (intraflagellar transport 74)	protein interactions	80173	126	2	19454	49	PRKN,AMOT
4.027e-02	-3.21	asymmetric, glutamatergic, excitatory synapse	cellular component	GO:0098985	16	1	19108	49	ADGRB3
4.033e-02	-3.21	Pathways in cancer	KEGG pathways	hsa05200	395	4	7161	24	LAMA4,CTBP1,FGFR3,EGF
4.035e-02	-3.21	transcription regulatory region nucleic acid binding	molecular function	GO:0001067	1487	8	18094	48	RFX4,RORA,TRPS1,PRDM16,SOX5,NFIA,NPAS3,ZBTB20
4.035e-02	-3.21	skin-chest-malignant_melanoma	COSMIC cancer mutations	skin-chest-malignant_melanoma	114	2	16828	47	SLC6A11,PREX2
4.041e-02	-3.21	HP1BP3 (heterochromatin protein 1 binding protein 3)	protein interactions	50809	302	3	19454	49	PRKN,PRDM16,NFIA
4.043e-02	-3.21	columnar/cuboidal epithelial cell maturation	biological process	GO:0002069	15	1	18204	50	GJA1
4.043e-02	-3.21	regulation of phospholipid transport	biological process	GO:2001138	15	1	18204	50	APOA1
4.043e-02	-3.21	cell migration involved in gastrulation	biological process	GO:0042074	15	1	18204	50	AMOT
4.043e-02	-3.21	neuroblast division	biological process	GO:0055057	15	1	18204	50	SOX5
4.043e-02	-3.21	protein homotrimerization	biological process	GO:0070207	15	1	18204	50	SLC1A2
4.043e-02	-3.21	exit from mitosis	biological process	GO:0010458	15	1	18204	50	NFIA
4.043e-02	-3.21	synapse maturation	biological process	GO:0060074	15	1	18204	50	NFIA
4.043e-02	-3.21	chondrocyte proliferation	biological process	GO:0035988	15	1	18204	50	FGFR3
4.043e-02	-3.21	cerebellar Purkinje cell layer formation	biological process	GO:0021694	15	1	18204	50	RORA
4.043e-02	-3.21	positive regulation of cholesterol metabolic process	biological process	GO:0090205	15	1	18204	50	APOA1
4.043e-02	-3.21	glucocorticoid metabolic process	biological process	GO:0008211	15	1	18204	50	APOA1
4.043e-02	-3.21	atrial cardiac muscle cell to AV node cell communication	biological process	GO:0086066	15	1	18204	50	GJA1
4.043e-02	-3.21	gamma-aminobutyric acid transport	biological process	GO:0015812	15	1	18204	50	SLC6A11
4.043e-02	-3.21	norepinephrine metabolic process	biological process	GO:0042415	15	1	18204	50	PRKN
4.069e-02	-3.20	Formin, FH2 domain	gene3d domains	1.20.58.2220	15	1	14470	40	FHOD3
4.074e-02	-3.20	ZZEF1 (zinc finger ZZ-type and EF-hand domain containing 1)	protein interactions	23140	127	2	19454	49	FGFRL1,PRKN
4.074e-02	-3.20	EPB41L4A (erythrocyte membrane protein band 4.1 like 4A)	protein interactions	64097	127	2	19454	49	FARP1,USP6NL
4.084e-02	-3.20	LDLRB	prosite domains	PS51120	13	1	12186	39	EGF
4.089e-02	-3.20	postsynaptic specialization membrane	cellular component	GO:0099634	125	2	19108	49	ADGRB3,SORCS2
4.107e-02	-3.19	regulation of synapse assembly	biological process	GO:0051963	117	2	18204	50	FARP1,ADGRB3
4.110e-02	-3.19	hypothalamus	COSMIC cancer mutations	hypothalamus	15	1	16828	47	QKI
4.110e-02	-3.19	ureter	COSMIC cancer mutations	ureter	15	1	16828	47	FGFR3
4.117e-02	-3.19	signaling receptor binding	molecular function	GO:0005102	1493	8	18094	48	APOA1,LAMA4,PTPRZ1,PLPP3,EGF,PTN,GJA1,PRKN
4.121e-02	-3.19	ZnF_GATA	smart domains	SM00401	12	1	9717	34	TRPS1
4.121e-02	-3.19	DWA	smart domains	SM00523	12	1	9717	34	NFIA
4.127e-02	-3.19	human chr3q13.31	chromosome location	human chr3q13.31	22	1	26134	50	ZBTB20
4.132e-02	-3.19	TEAD2 (TEA domain transcription factor 2)	protein interactions	8463	128	2	19454	49	TRPS1,ZBTB20
4.132e-02	-3.19	MYB (MYB proto-oncogene, transcription factor)	protein interactions	4602	128	2	19454	49	NFIA,TRPS1
4.132e-02	-3.19	SLC30A5 (solute carrier family 30 member 5)	protein interactions	64924	128	2	19454	49	GJA1,CTBP1
4.132e-02	-3.19	ATF7IP (activating transcription factor 7 interacting protein)	protein interactions	55729	128	2	19454	49	SOX5,LAMA4
4.134e-02	-3.19	FH2	pfam domains	PF02181	15	1	17795	50	FHOD3
4.134e-02	-3.19	DAGK_cat	pfam domains	PF00781	15	1	17795	50	DGKB
4.134e-02	-3.19	FKBP_C	pfam domains	PF00254	15	1	17795	50	FKBP5
4.138e-02	-3.18	NS-malignant_melanoma	COSMIC cancer mutations	NS-malignant_melanoma	3420	15	16828	47	DGKB,LRIG1,PREX2,SNTB1,GRK5,SLC39A12,FGFR3,ELOVL2,PRDM16,TNS3,GPC5,NCKAP5,PTPRZ1,AMOT,RFX4
4.141e-02	-3.18	ATAD3A (ATPase family AAA domain containing 3A)	protein interactions	55210	305	3	19454	49	PRKN,PRDM16,SOX5
4.150e-02	-3.18	ERBB2 Regulates Cell Motility	REACTOME pathways	R-HSA-6785631	15	1	10285	29	EGF
4.150e-02	-3.18	Depolymerisation of the Nuclear Lamina	REACTOME pathways	R-HSA-4419969	15	1	10285	29	LPIN2
4.150e-02	-3.18	alpha-linolenic acid (ALA) metabolism	REACTOME pathways	R-HSA-2046106	15	1	10285	29	ELOVL2
4.150e-02	-3.18	alpha-linolenic (omega3) and linoleic (omega6) acid metabolism	REACTOME pathways	R-HSA-2046104	15	1	10285	29	ELOVL2
4.158e-02	-3.18	SH3 domain binding	molecular function	GO:0017124	122	2	18094	48	QKI,PRKN
4.163e-02	-3.18	water channel activity	molecular function	GO:0015250	16	1	18094	48	AQP4
4.163e-02	-3.18	sodium:chloride symporter activity	molecular function	GO:0015378	16	1	18094	48	SLC6A11
4.163e-02	-3.18	oxysterol binding	molecular function	GO:0008142	16	1	18094	48	RORA
4.190e-02	-3.17	ALDH2 (aldehyde dehydrogenase 2 family member)	protein interactions	217	129	2	19454	49	APOA1,PRKN
4.190e-02	-3.17	POLA2 (DNA polymerase alpha 2, accessory subunit)	protein interactions	23649	129	2	19454	49	PRKN,FGFR3
4.193e-02	-3.17	response to stimulus	biological process	GO:0050896	7803	28	18204	50	PREX2,PTN,FKBP5,SLC6A11,AQP4,SLC1A2,BCAR3,EGF,LPIN2,FARP1,SLC1A3,ZBTB20,APOA1,GJA1,AMOT,DGKB,NFIA,ADGRB3,SLC39A12,SORCS2,SOX5,PRKN,PREX1,RORA,GRK5,FGFR3,PLPP3,FGFRL1
4.198e-02	-3.17	Pef1 (penta-EF hand domain containing 1)	protein interactions	67898	17	1	19454	49	QKI
4.198e-02	-3.17	TAGAP (T cell activation RhoGTPase activating protein)	protein interactions	117289	17	1	19454	49	SNTB1
4.198e-02	-3.17	CYP20A1 (cytochrome P450 family 20 subfamily A member 1)	protein interactions	57404	17	1	19454	49	PRKN
4.198e-02	-3.17	TRIM34 (tripartite motif containing 34)	protein interactions	53840	17	1	19454	49	PRKN
4.198e-02	-3.17	TAC3 (tachykinin precursor 3)	protein interactions	6866	17	1	19454	49	PTN
4.198e-02	-3.17	STK32A (serine/threonine kinase 32A)	protein interactions	202374	17	1	19454	49	FKBP5
4.198e-02	-3.17	IGKV2D-29 (immunoglobulin kappa variable 2D-29)	protein interactions	28882	17	1	19454	49	PRKN
4.198e-02	-3.17	PLCE1 (phospholipase C epsilon 1)	protein interactions	51196	17	1	19454	49	FKBP5
4.198e-02	-3.17	PLA2G15 (phospholipase A2 group XV)	protein interactions	23659	17	1	19454	49	PRKN
4.198e-02	-3.17	MSANTD2 (Myb/SANT DNA binding domain containing 2)	protein interactions	79684	17	1	19454	49	SOX5
4.198e-02	-3.17	DENND5B (DENN domain containing 5B)	protein interactions	160518	17	1	19454	49	GJA1
4.198e-02	-3.17	Shcbp1 (Shc SH2-domain binding protein 1)	protein interactions	20419	17	1	19454	49	GPC5
4.198e-02	-3.17	KYAT1 (kynurenine aminotransferase 1)	protein interactions	883	17	1	19454	49	PRKN
4.198e-02	-3.17	HPR (haptoglobin-related protein)	protein interactions	3250	17	1	19454	49	APOA1
4.198e-02	-3.17	Nufip2 (nuclear FMR1 interacting protein 2)	protein interactions	68564	17	1	19454	49	CTBP1
4.198e-02	-3.17	FLRT3 (fibronectin leucine rich transmembrane protein 3)	protein interactions	23767	17	1	19454	49	GJA1
4.209e-02	-3.17	ACTA2 (actin alpha 2, smooth muscle)	protein interactions	59	307	3	19454	49	PRKN,GJA1,PTPRZ1
4.210e-02	-3.17	cellular response to organic substance	biological process	GO:0071310	1716	9	18204	50	SLC1A3,PRKN,ZBTB20,RORA,AQP4,GJA1,SLC1A2,BCAR3,LPIN2
4.210e-02	-3.17	urinary_tract	COSMIC cancer mutations	urinary_tract	14112	44	16828	47	LRIG1,DGKB,TRPS1,GPM6B,SNTB1,SLC4A4,FGFRL1,SOX5,SLC6A11,NPAS3,AMOT,ASPA,SORCS2,FHOD3,SLC1A2,ELOVL2,FGFR3,LAMA4,PREX1,FKBP5,ZBTB20,UNC93A,NCKAP5,QKI,GJA1,EGF,GRK5,SLC39A12,USP6NL,SLC1A3,GPC5,TNS3,PTPRZ1,CTBP1,LPIN2,RFX4,MSI2,NFIA,PREX2,PRDM16,FARP1,RORA,PTN,BCAR3
4.210e-02	-3.17	bladder	COSMIC cancer mutations	bladder	14112	44	16828	47	BCAR3,GJA1,NCKAP5,QKI,RORA,FKBP5,ZBTB20,PTN,FARP1,UNC93A,SLC1A2,LAMA4,PREX1,PRDM16,ELOVL2,FGFR3,NFIA,PREX2,FHOD3,RFX4,LPIN2,AMOT,PTPRZ1,NPAS3,CTBP1,SORCS2,MSI2,ASPA,USP6NL,SLC1A3,GPC5,TNS3,SLC6A11,GRK5,SNTB1,EGF,FGFRL1,SOX5,SLC4A4,SLC39A12,LRIG1,DGKB,GPM6B,TRPS1
4.211e-02	-3.17	cell-cell junction	cellular component	GO:0005911	513	4	19108	49	AMOT,PLPP3,GJA1,FGFRL1
4.229e-02	-3.16	central_nervous_system-brain-glioma-oligoastrocytoma_Grade_III	COSMIC cancer mutations	central_nervous_system-brain-glioma-oligoastrocytoma_Grade_III	117	2	16828	47	FGFR3,AMOT
4.235e-02	-3.16	Ez/rad/moesin-like	interpro domains	IPR000798	16	1	18521	50	FARP1
4.244e-02	-3.16	lung-carcinoma-adenocarcinoma	COSMIC cancer mutations	lung-carcinoma-adenocarcinoma	15133	46	16828	47	GPC5,TNS3,USP6NL,SLC1A3,MSI2,PTPRZ1,CTBP1,RFX4,LPIN2,SLC39A12,EGF,GRK5,FARP1,RORA,PTN,BCAR3,NFIA,PREX2,PRDM16,SLC6A11,ASPA,SORCS2,NPAS3,AMOT,TRPS1,GPM6B,LRIG1,DGKB,SLC4A4,FGFRL1,SOX5,SNTB1,UNC93A,NHSL1,FKBP5,ZBTB20,AQP4,NCKAP5,QKI,GJA1,FHOD3,ELOVL2,FGFR3,LAMA4,PREX1,SLC1A2
4.249e-02	-3.16	PASK (PAS domain containing serine/threonine kinase)	protein interactions	23178	130	2	19454	49	TNS3,PRKN
4.249e-02	-3.16	SNX5 (sorting nexin 5)	protein interactions	27131	130	2	19454	49	GJA1,PRKN
4.249e-02	-3.16	DVL1 (dishevelled segment polarity protein 1)	protein interactions	1855	130	2	19454	49	CTBP1,GJA1
4.273e-02	-3.15	presynaptic active zone cytoplasmic component	cellular component	GO:0098831	17	1	19108	49	CTBP1
4.274e-02	-3.15	Fatty acid biosynthesis, elongation, endoplasmic reticulum	KEGG pathways	M00415	13	1	7161	24	ELOVL2
4.274e-02	-3.15	Fatty acid biosynthesis, elongation, endoplasmic reticulum	KEGG pathways	hsa_M00415	13	1	7161	24	ELOVL2
4.277e-02	-3.15	ITCH (itchy E3 ubiquitin protein ligase)	protein interactions	83737	309	3	19454	49	GJA1,RORA,AMOT
4.307e-02	-3.14	regulation of hepatocyte proliferation	biological process	GO:2000345	16	1	18204	50	PTN
4.307e-02	-3.14	estrous cycle	biological process	GO:0044849	16	1	18204	50	PTN
4.307e-02	-3.14	non-proteinogenic amino acid biosynthetic process	biological process	GO:0170043	16	1	18204	50	SLC1A3
4.307e-02	-3.14	protein K6-linked ubiquitination	biological process	GO:0085020	16	1	18204	50	PRKN
4.307e-02	-3.14	positive regulation of autophagy of mitochondrion	biological process	GO:1903599	16	1	18204	50	PRKN
4.307e-02	-3.14	positive regulation of dendrite development	biological process	GO:1900006	16	1	18204	50	PTN
4.307e-02	-3.14	nonribosomal peptide biosynthetic process	biological process	GO:0019184	16	1	18204	50	SLC1A2
4.307e-02	-3.14	asymmetric cell division	biological process	GO:0008356	16	1	18204	50	SOX5
4.308e-02	-3.14	NCOA2 (nuclear receptor coactivator 2)	protein interactions	10499	131	2	19454	49	NFIA,RORA
4.308e-02	-3.14	ZNF609 (zinc finger protein 609)	protein interactions	23060	131	2	19454	49	NFIA,SOX5
4.308e-02	-3.14	OLA1 (Obg like ATPase 1)	protein interactions	29789	131	2	19454	49	PRKN,GRK5
4.308e-02	-3.14	MAPKAPK2 (MAPK activated protein kinase 2)	protein interactions	9261	131	2	19454	49	PRKN,EGF
4.308e-02	-3.14	TET2 (tet methylcytosine dioxygenase 2)	protein interactions	54790	131	2	19454	49	APOA1,BCAR3
4.312e-02	-3.14	PRPF6 (pre-mRNA processing factor 6)	protein interactions	24148	310	3	19454	49	QKI,CTBP1,PRKN
4.312e-02	-3.14	C11orf52 (chromosome 11 open reading frame 52)	protein interactions	91894	310	3	19454	49	AMOT,USP6NL,FARP1
4.338e-02	-3.14	positive regulation of macromolecule metabolic process	biological process	GO:0010604	3485	15	18204	50	CTBP1,RFX4,LPIN2,QKI,EGF,BCAR3,NFIA,ZBTB20,PRKN,GJA1,RORA,FGFR3,PLPP3,NPAS3,PRDM16
4.339e-02	-3.14	transcription coregulator activity	molecular function	GO:0003712	501	4	18094	48	CTBP1,PRKN,LPIN2,PRDM16
4.366e-02	-3.13	acinar_carcinoma	COSMIC cancer mutations	acinar_carcinoma	1978	10	16828	47	ZBTB20,NHSL1,FHOD3,AMOT,GRK5,QKI,PTPRZ1,SORCS2,SOX5,SLC39A12
4.366e-02	-3.13	pancreas-carcinoma-acinar_carcinoma	COSMIC cancer mutations	pancreas-carcinoma-acinar_carcinoma	1978	10	16828	47	GRK5,AMOT,PTPRZ1,QKI,SOX5,SORCS2,SLC39A12,ZBTB20,NHSL1,FHOD3
4.367e-02	-3.13	ADD3 (adducin 3)	protein interactions	120	132	2	19454	49	GJA1,PRKN
4.367e-02	-3.13	TRAPPC5 (trafficking protein particle complex subunit 5)	protein interactions	126003	132	2	19454	49	CTBP1,PRKN
4.367e-02	-3.13	INA (internexin neuronal intermediate filament protein alpha)	protein interactions	9118	132	2	19454	49	CTBP1,PRKN
4.378e-02	-3.13	flank	COSMIC cancer mutations	flank	16	1	16828	47	FGFR3
4.378e-02	-3.13	urinary_tract-carcinoma	COSMIC cancer mutations	urinary_tract-carcinoma	16	1	16828	47	FGFR3
4.378e-02	-3.13	normal	COSMIC cancer mutations	normal	16	1	16828	47	FGFR3
4.378e-02	-3.13	renal_pelvis	COSMIC cancer mutations	renal_pelvis	16	1	16828	47	FGFR3
4.381e-02	-3.13	RTN4 (reticulon 4)	protein interactions	57142	312	3	19454	49	CTBP1,LAMA4,PRKN
4.381e-02	-3.13	PRKCI (protein kinase C iota)	protein interactions	5584	312	3	19454	49	AMOT,CTBP1,PRKN
4.383e-02	-3.13	EMD (emerin)	protein interactions	2010	771	5	19454	49	ELOVL2,GJA1,PRKN,FGFR3,EGF
4.391e-02	-3.13	TRIAD	prosite domains	PS51873	14	1	12186	39	PRKN
4.408e-02	-3.12	Platelet activation, signaling and aggregation	REACTOME pathways	R-HSA-76002	282	3	10285	29	APOA1,EGF,DGKB
4.413e-02	-3.12	right_lower_lobe	COSMIC cancer mutations	right_lower_lobe	5692	22	16828	47	GRK5,PREX1,PRDM16,SOX5,LAMA4,SLC4A4,SLC39A12,DGKB,LRIG1,GPM6B,FHOD3,TRPS1,CTBP1,NPAS3,NCKAP5,PTPRZ1,ASPA,PTN,SLC1A3,USP6NL,GPC5,SLC6A11
4.413e-02	-3.12	lung-right_lower_lobe-carcinoma-adenocarcinoma	COSMIC cancer mutations	lung-right_lower_lobe-carcinoma-adenocarcinoma	5692	22	16828	47	PRDM16,PREX1,LAMA4,SOX5,SLC39A12,SLC4A4,GRK5,GPM6B,FHOD3,TRPS1,DGKB,LRIG1,ASPA,NPAS3,CTBP1,NCKAP5,PTPRZ1,GPC5,SLC6A11,PTN,SLC1A3,USP6NL
4.415e-02	-3.12	regulation of canonical NF-kappaB signal transduction	biological process	GO:0043122	287	3	18204	50	PRKN,GJA1,RORA
4.417e-02	-3.12	transmembrane receptor protein phosphatase activity	molecular function	GO:0019198	17	1	18094	48	PTPRZ1
4.417e-02	-3.12	transmembrane receptor protein tyrosine phosphatase activity	molecular function	GO:0005001	17	1	18094	48	PTPRZ1
4.420e-02	-3.12	Constitutive Signaling by EGFRvIII	REACTOME pathways	R-HSA-5637810	16	1	10285	29	EGF
4.420e-02	-3.12	GRB2 events in ERBB2 signaling	REACTOME pathways	R-HSA-1963640	16	1	10285	29	EGF
4.420e-02	-3.12	Signaling by EGFRvIII in Cancer	REACTOME pathways	R-HSA-5637812	16	1	10285	29	EGF
4.420e-02	-3.12	PI3K events in ERBB2 signaling	REACTOME pathways	R-HSA-1963642	16	1	10285	29	EGF
4.424e-02	-3.12	Ig-like_fold	interpro domains	IPR013783	721	5	18521	50	SORCS2,FGFRL1,FGFR3,PTPRZ1,LRIG1
4.427e-02	-3.12	hairy_cell_leukaemia	COSMIC cancer mutations	hairy_cell_leukaemia	1440	8	16828	47	PREX2,AMOT,RFX4,NCKAP5,PTPRZ1,SORCS2,SLC39A12,FGFR3
4.427e-02	-3.12	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-hairy_cell_leukaemia	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-hairy_cell_leukaemia	1440	8	16828	47	NCKAP5,PTPRZ1,AMOT,RFX4,SLC39A12,FGFR3,SORCS2,PREX2
4.427e-02	-3.12	CBS (cystathionine beta-synthase)	protein interactions	875	133	2	19454	49	PREX1,PRKN
4.427e-02	-3.12	LURAP1 (leucine rich adaptor protein 1)	protein interactions	541468	133	2	19454	49	AMOT,SNTB1
4.427e-02	-3.12	HAUS5 (HAUS augmin like complex subunit 5)	protein interactions	23354	133	2	19454	49	FKBP5,PRKN
4.427e-02	-3.12	PLD2 (phospholipase D2)	protein interactions	5338	133	2	19454	49	PRKN,FKBP5
4.433e-02	-3.12	Composition of Lipid Particles	WikiPathways	WP3601	10	1	5310	24	APOA1
4.433e-02	-3.12	stomach-carcinoma-adenocarcinoma	COSMIC cancer mutations	stomach-carcinoma-adenocarcinoma	15150	46	16828	47	QKI,NCKAP5,GJA1,AQP4,ZBTB20,FKBP5,UNC93A,SLC1A2,FGFR3,ELOVL2,PREX1,LAMA4,APOA1,FHOD3,NPAS3,AMOT,ASPA,SORCS2,SLC6A11,SNTB1,SLC4A4,SOX5,FGFRL1,DGKB,LRIG1,TRPS1,GPM6B,BCAR3,FARP1,PTN,RORA,PRDM16,PREX2,NFIA,CTBP1,PTPRZ1,RFX4,LPIN2,MSI2,SLC1A3,USP6NL,TNS3,GPC5,EGF,GRK5,SLC39A12
4.440e-02	-3.11	IRGC (immunity related GTPase cinema)	protein interactions	56269	18	1	19454	49	PRKN
4.440e-02	-3.11	NME6 (NME/NM23 nucleoside diphosphate kinase 6)	protein interactions	10201	18	1	19454	49	PRKN
4.440e-02	-3.11	SHISA2 (shisa family member 2)	protein interactions	387914	18	1	19454	49	GJA1
4.440e-02	-3.11	RYR3 (ryanodine receptor 3)	protein interactions	6263	18	1	19454	49	PRKN
4.440e-02	-3.11	Wwtr1 (WW domain containing transcription regulator 1)	protein interactions	97064	18	1	19454	49	AMOT
4.440e-02	-3.11	AKAP14 (A-kinase anchoring protein 14)	protein interactions	158798	18	1	19454	49	PRKN
4.440e-02	-3.11	DLX2 (distal-less homeobox 2)	protein interactions	1746	18	1	19454	49	PRKN
4.440e-02	-3.11	ARMC9 (armadillo repeat containing 9)	protein interactions	80210	18	1	19454	49	PRKN
4.440e-02	-3.11	DCAF17 (DDB1 and CUL4 associated factor 17)	protein interactions	80067	18	1	19454	49	PREX1
4.440e-02	-3.11	GDAP2 (ganglioside induced differentiation associated protein 2)	protein interactions	54834	18	1	19454	49	PRKN
4.440e-02	-3.11	OXNAD1 (oxidoreductase NAD binding domain containing 1)	protein interactions	92106	18	1	19454	49	PRKN
4.440e-02	-3.11	SNX15 (sorting nexin 15)	protein interactions	29907	18	1	19454	49	PRKN
4.440e-02	-3.11	TKTL2 (transketolase like 2)	protein interactions	84076	18	1	19454	49	PRKN
4.440e-02	-3.11	TLCD1 (TLC domain containing 1)	protein interactions	116238	18	1	19454	49	SLC39A12
4.440e-02	-3.11	NECTIN1 (nectin cell adhesion molecule 1)	protein interactions	5818	18	1	19454	49	FGFR3
4.440e-02	-3.11	PNMA3 (PNMA family member 3)	protein interactions	29944	18	1	19454	49	PRKN
4.440e-02	-3.11	GRK3 (G protein-coupled receptor kinase 3)	protein interactions	157	18	1	19454	49	PRKN
4.440e-02	-3.11	CYP2E1 (cytochrome P450 family 2 subfamily E member 1)	protein interactions	1571	18	1	19454	49	PTN
4.440e-02	-3.11	RAI2 (retinoic acid induced 2)	protein interactions	10742	18	1	19454	49	CTBP1
4.440e-02	-3.11	COX3 (cytochrome c oxidase subunit III)	protein interactions	4514	18	1	19454	49	PRKN
4.440e-02	-3.11	TOR2A (torsin family 2 member A)	protein interactions	27433	18	1	19454	49	CTBP1
4.440e-02	-3.11	GRIK5 (glutamate ionotropic receptor kainate type subunit 5)	protein interactions	2901	18	1	19454	49	PRKN
4.440e-02	-3.11	FRMD8 (FERM domain containing 8)	protein interactions	83786	18	1	19454	49	PRKN
4.440e-02	-3.11	GBP6 (guanylate binding protein family member 6)	protein interactions	163351	18	1	19454	49	PRKN
4.440e-02	-3.11	HMBS (hydroxymethylbilane synthase)	protein interactions	3145	18	1	19454	49	PRKN
4.440e-02	-3.11	RANBP17 (RAN binding protein 17)	protein interactions	64901	18	1	19454	49	PRKN
4.445e-02	-3.11	cell projection organization	biological process	GO:0030030	1200	7	18204	50	FARP1,PTPRZ1,GPM6B,SLC39A12,PREX2,PTN,RFX4
4.449e-02	-3.11	tight junction	cellular component	GO:0070160	131	2	19108	49	AMOT,GJA1
4.451e-02	-3.11	ARIH2 (ariadne RBR E3 ubiquitin protein ligase 2)	protein interactions	10425	314	3	19454	49	PRKN,CTBP1,PTN
4.451e-02	-3.11	ATP5PO (ATP synthase peripheral stalk subunit OSCP)	protein interactions	539	314	3	19454	49	PRKN,PRDM16,PREX1
4.457e-02	-3.11	FA	smart domains	SM01195	13	1	9717	34	FARP1
4.461e-02	-3.11	regulation of organelle organization	biological process	GO:0033043	1201	7	18204	50	SLC39A12,USP6NL,APOA1,PREX1,PRKN,GPM6B,EGF
4.471e-02	-3.11	seminoma	COSMIC cancer mutations	seminoma	700	5	16828	47	TRPS1,FGFR3,LAMA4,PREX2,GRK5
4.475e-02	-3.11	positive regulation of macromolecule biosynthetic process	biological process	GO:0010557	2592	12	18204	50	PRKN,ZBTB20,RORA,GJA1,NPAS3,PRDM16,CTBP1,RFX4,EGF,QKI,LPIN2,NFIA
4.493e-02	-3.10	NAD/diacylglycerol_kinase_sf	interpro domains	IPR016064	17	1	18521	50	DGKB
4.493e-02	-3.10	CA_dom_sf	interpro domains	IPR036398	17	1	18521	50	PTPRZ1
4.493e-02	-3.10	CA_dom	interpro domains	IPR001148	17	1	18521	50	PTPRZ1
4.493e-02	-3.10	ATP-NAD_kinase_N	interpro domains	IPR017438	17	1	18521	50	DGKB
4.519e-02	-3.10	dystrophin-associated glycoprotein complex	cellular component	GO:0016010	18	1	19108	49	SNTB1
4.547e-02	-3.09	SOX15 (SRY-box transcription factor 15)	protein interactions	6665	135	2	19454	49	TRPS1,NFIA
4.547e-02	-3.09	JAK3 (Janus kinase 3)	protein interactions	3718	135	2	19454	49	APOA1,FKBP5
4.547e-02	-3.09	URI1 (URI1 prefoldin like chaperone)	protein interactions	8725	135	2	19454	49	FGFR3,FKBP5
4.547e-02	-3.09	EML4 (EMAP like 4)	protein interactions	27436	135	2	19454	49	FKBP5,PRKN
4.547e-02	-3.09	NTRK2 (neurotrophic receptor tyrosine kinase 2)	protein interactions	4915	135	2	19454	49	PRKN,USP6NL
4.547e-02	-3.09	BCKDK (branched chain keto acid dehydrogenase kinase)	protein interactions	10295	135	2	19454	49	FKBP5,PRKN
4.557e-02	-3.09	protein-macromolecule adaptor activity	molecular function	GO:0030674	989	6	18094	48	PRKN,FKBP5,CTBP1,LPIN2,QKI,PRDM16
4.560e-02	-3.09	positive regulation of cell-substrate adhesion	biological process	GO:0010811	124	2	18204	50	APOA1,PREX1
4.560e-02	-3.09	positive regulation of lipid metabolic process	biological process	GO:0045834	124	2	18204	50	ZBTB20,APOA1
4.570e-02	-3.09	regulation of receptor clustering	biological process	GO:1903909	17	1	18204	50	FARP1
4.570e-02	-3.09	postsynaptic actin cytoskeleton organization	biological process	GO:0098974	17	1	18204	50	FARP1
4.570e-02	-3.09	white fat cell differentiation	biological process	GO:0050872	17	1	18204	50	CTBP1
4.570e-02	-3.09	T-helper 17 type immune response	biological process	GO:0072538	17	1	18204	50	RORA
4.570e-02	-3.09	protein trimerization	biological process	GO:0070206	17	1	18204	50	SLC1A2
4.570e-02	-3.09	synaptic transmission, dopaminergic	biological process	GO:0001963	17	1	18204	50	PRKN
4.570e-02	-3.09	reverse cholesterol transport	biological process	GO:0043691	17	1	18204	50	APOA1
4.570e-02	-3.09	positive regulation of protein polyubiquitination	biological process	GO:1902916	17	1	18204	50	PRKN
4.570e-02	-3.09	negative regulation by host of viral process	biological process	GO:0044793	17	1	18204	50	PRKN
4.570e-02	-3.09	regulation of Golgi organization	biological process	GO:1903358	17	1	18204	50	USP6NL
4.570e-02	-3.09	regulation of trophoblast cell migration	biological process	GO:1901163	17	1	18204	50	GJA1
4.570e-02	-3.09	high-density lipoprotein particle remodeling	biological process	GO:0034375	17	1	18204	50	APOA1
4.570e-02	-3.09	cGMP metabolic process	biological process	GO:0046068	17	1	18204	50	RORA
4.570e-02	-3.09	phospholipid homeostasis	biological process	GO:0055091	17	1	18204	50	APOA1
4.570e-02	-3.09	mitochondrial fission	biological process	GO:0000266	17	1	18204	50	PRKN
4.570e-02	-3.09	ureter development	biological process	GO:0072189	17	1	18204	50	NFIA
4.570e-02	-3.09	cell communication by electrical coupling involved in cardiac conduction	biological process	GO:0086064	17	1	18204	50	GJA1
4.585e-02	-3.08	SH2	prosite domains	PS50001	107	2	12186	39	BCAR3,TNS3
4.599e-02	-3.08	Alpha carbonic anhydrase	gene3d domains	3.10.200.10	17	1	14470	40	PTPRZ1
4.608e-02	-3.08	SEH1L (SEH1 like nucleoporin)	protein interactions	81929	136	2	19454	49	PRKN,FGFR3
4.608e-02	-3.08	TRIM13 (tripartite motif containing 13)	protein interactions	10206	136	2	19454	49	GJA1,ELOVL2
4.608e-02	-3.08	PYGB (glycogen phosphorylase B)	protein interactions	5834	136	2	19454	49	FKBP5,PRKN
4.608e-02	-3.08	ROCK2 (Rho associated coiled-coil containing protein kinase 2)	protein interactions	9475	136	2	19454	49	GJA1,PRKN
4.608e-02	-3.08	NIBAN2 (niban apoptosis regulator 2)	protein interactions	64855	136	2	19454	49	GJA1,PRKN
4.613e-02	-3.08	PDZ	pfam domains	PF00595	122	2	17795	50	SNTB1,PREX2
4.626e-02	-3.07	mammary gland development	biological process	GO:0030879	125	2	18204	50	GJA1,EGF
4.631e-02	-3.07	modulation of chemical synaptic transmission	biological process	GO:0050804	494	4	18204	50	SORCS2,PTN,SLC1A3,PRKN
4.646e-02	-3.07	breast-carcinoma-neuroendocrine_carcinoma	COSMIC cancer mutations	breast-carcinoma-neuroendocrine_carcinoma	17	1	16828	47	FGFR3
4.646e-02	-3.07	optic_nerve	COSMIC cancer mutations	optic_nerve	17	1	16828	47	QKI
4.646e-02	-3.07	squamous_cell_carcinoma_BRAF_inhibitor_related	COSMIC cancer mutations	squamous_cell_carcinoma_BRAF_inhibitor_related	17	1	16828	47	FGFR3
4.646e-02	-3.07	non_chronically_sun_exposed_site	COSMIC cancer mutations	non_chronically_sun_exposed_site	17	1	16828	47	FGFR3
4.646e-02	-3.07	skin-non_chronically_sun_exposed_site-malignant_melanoma	COSMIC cancer mutations	skin-non_chronically_sun_exposed_site-malignant_melanoma	17	1	16828	47	FGFR3
4.646e-02	-3.07	skin-other-verrucal_keratosis_BRAF_inhibitor_related	COSMIC cancer mutations	skin-other-verrucal_keratosis_BRAF_inhibitor_related	17	1	16828	47	FGFR3
4.646e-02	-3.07	skin-carcinoma-squamous_cell_carcinoma_BRAF_inhibitor_related	COSMIC cancer mutations	skin-carcinoma-squamous_cell_carcinoma_BRAF_inhibitor_related	17	1	16828	47	FGFR3
4.646e-02	-3.07	central_nervous_system-optic_nerve-glioma-astrocytoma_Grade_I	COSMIC cancer mutations	central_nervous_system-optic_nerve-glioma-astrocytoma_Grade_I	17	1	16828	47	QKI
4.646e-02	-3.07	verrucal_keratosis_BRAF_inhibitor_related	COSMIC cancer mutations	verrucal_keratosis_BRAF_inhibitor_related	17	1	16828	47	FGFR3
4.660e-02	-3.07	regulation of trans-synaptic signaling	biological process	GO:0099177	495	4	18204	50	SLC1A3,PTN,SORCS2,PRKN
4.662e-02	-3.07	RUVBL1 (RuvB like AAA ATPase 1)	protein interactions	8607	540	4	19454	49	FKBP5,RORA,GRK5,PRKN
4.669e-02	-3.06	NUP85 (nucleoporin 85)	protein interactions	79902	137	2	19454	49	FKBP5,PRKN
4.669e-02	-3.06	CLUH (clustered mitochondria homolog)	protein interactions	23277	137	2	19454	49	PRKN,FGFR3
4.669e-02	-3.06	WDR12 (WD repeat domain 12)	protein interactions	55759	137	2	19454	49	PRKN,GRK5
4.669e-02	-3.06	C3 (complement C3)	protein interactions	718	137	2	19454	49	PRKN,GJA1
4.671e-02	-3.06	transmembrane receptor protein tyrosine kinase activator activity	molecular function	GO:0030297	18	1	18094	48	EGF
4.671e-02	-3.06	monoatomic anion:sodium symporter activity	molecular function	GO:0015373	18	1	18094	48	SLC6A11
4.671e-02	-3.06	ubiquitin-specific protease binding	molecular function	GO:1990381	18	1	18094	48	PRKN
4.673e-02	-3.06	Carb_anhydrase	pfam domains	PF00194	17	1	17795	50	PTPRZ1
4.673e-02	-3.06	PRDM2_PR	pfam domains	PF21549	17	1	17795	50	PRDM16
4.681e-02	-3.06	RCVRN (recoverin)	protein interactions	5957	19	1	19454	49	GRK5
4.681e-02	-3.06	INPP4A (inositol polyphosphate-4-phosphatase type I A)	protein interactions	3631	19	1	19454	49	PRKN
4.681e-02	-3.06	TNR (tenascin R)	protein interactions	7143	19	1	19454	49	PTPRZ1
4.681e-02	-3.06	PDIK1L (PDLIM1 interacting kinase 1 like)	protein interactions	149420	19	1	19454	49	FKBP5
4.681e-02	-3.06	FBLN7 (fibulin 7)	protein interactions	129804	19	1	19454	49	APOA1
4.681e-02	-3.06	DEFB125 (defensin beta 125)	protein interactions	245938	19	1	19454	49	GJA1
4.681e-02	-3.06	PCDH19 (protocadherin 19)	protein interactions	57526	19	1	19454	49	GJA1
4.681e-02	-3.06	RTTN (rotatin)	protein interactions	25914	19	1	19454	49	PRKN
4.681e-02	-3.06	ACOT11 (acyl-CoA thioesterase 11)	protein interactions	26027	19	1	19454	49	PRKN
4.681e-02	-3.06	HSPBAP1 (HSPB1 associated protein 1)	protein interactions	79663	19	1	19454	49	PTN
4.681e-02	-3.06	INKA1 (inka box actin regulator 1)	protein interactions	389119	19	1	19454	49	ZBTB20
4.681e-02	-3.06	PARVB (parvin beta)	protein interactions	29780	19	1	19454	49	PRKN
4.681e-02	-3.06	GNAL (G protein subunit alpha L)	protein interactions	2774	19	1	19454	49	PRKN
4.681e-02	-3.06	APOBEC3G (apolipoprotein B mRNA editing enzyme catalytic subunit 3G)	protein interactions	60489	19	1	19454	49	PTN
4.681e-02	-3.06	ZNF532 (zinc finger protein 532)	protein interactions	55205	19	1	19454	49	PRKN
4.681e-02	-3.06	SPZ1 (spermatogenic leucine zipper 1)	protein interactions	84654	19	1	19454	49	SNTB1
4.681e-02	-3.06	HMGCLL1 (3-hydroxy-3-methylglutaryl-CoA lyase like 1)	protein interactions	54511	19	1	19454	49	APOA1
4.681e-02	-3.06	CEP68 (centrosomal protein 68)	protein interactions	23177	19	1	19454	49	CTBP1
4.681e-02	-3.06	DCST1 (DC-STAMP domain containing 1)	protein interactions	149095	19	1	19454	49	PRKN
4.681e-02	-3.06	DNAH5 (dynein axonemal heavy chain 5)	protein interactions	1767	19	1	19454	49	PRKN
4.697e-02	-3.06	DAGK	prosite domains	PS50146	15	1	12186	39	DGKB
4.697e-02	-3.06	FKBP_PPIASE	prosite domains	PS50059	15	1	12186	39	FKBP5
4.697e-02	-3.06	FH2	prosite domains	PS51444	15	1	12186	39	FHOD3
4.699e-02	-3.06	ACTA1 (actin alpha 1, skeletal muscle)	protein interactions	58	321	3	19454	49	PRKN,USP6NL,AMOT
4.711e-02	-3.06	thyroid-carcinoma-medullary_carcinoma	COSMIC cancer mutations	thyroid-carcinoma-medullary_carcinoma	290	3	16828	47	SLC1A2,PTN,FGFR3
4.711e-02	-3.06	medullary_carcinoma	COSMIC cancer mutations	medullary_carcinoma	290	3	16828	47	PTN,SLC1A2,FGFR3
4.720e-02	-3.05	Immunoglobulins	gene3d domains	2.60.40.10	721	5	14470	40	LRIG1,FGFR3,FGFRL1,SORCS2,PTPRZ1
4.720e-02	-3.05	MINTRINSICP	prints domains	PR00783	14	1	5227	18	AQP4
4.725e-02	-3.05	regulation of endocytosis	biological process	GO:0030100	295	3	18204	50	APOA1,PRKN,EGF
4.730e-02	-3.05	STAM2 (signal transducing adaptor molecule 2)	protein interactions	10254	138	2	19454	49	PRKN,GJA1
4.730e-02	-3.05	GRK6 (G protein-coupled receptor kinase 6)	protein interactions	2870	138	2	19454	49	FKBP5,GRK5
4.737e-02	-3.05	PPARA activates gene expression	REACTOME pathways	R-HSA-1989781	124	2	10285	29	APOA1,RORA
4.750e-02	-3.05	monoatomic ion transport	biological process	GO:0006811	964	6	18204	50	SLC1A2,SLC6A11,SLC4A4,GJA1,SLC39A12,SLC1A3
4.750e-02	-3.05	anatomical structure formation involved in morphogenesis	biological process	GO:0048646	964	6	18204	50	SLC39A12,EGF,ADGRB3,FHOD3,AMOT,RORA
4.752e-02	-3.05	PPIase_dom_sf	interpro domains	IPR046357	18	1	18521	50	FKBP5
4.752e-02	-3.05	Leu-rich_rpt_4	interpro domains	IPR025875	18	1	18521	50	LRIG1
4.752e-02	-3.05	P_Acid_Pase_2/haloperoxidase	interpro domains	IPR000326	18	1	18521	50	PLPP3
4.752e-02	-3.05	P_Acid_Pase_2/haloperoxi_sf	interpro domains	IPR036938	18	1	18521	50	PLPP3
4.761e-02	-3.04	postsynaptic density	cellular component	GO:0014069	317	3	19108	49	PRKN,SORCS2,ADGRB3
4.771e-02	-3.04	STOM (stomatin)	protein interactions	2040	323	3	19454	49	GJA1,PRKN,GPM6B
4.771e-02	-3.04	ATP2A2 (ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2)	protein interactions	488	323	3	19454	49	PRDM16,PRKN,SLC4A4
4.792e-02	-3.04	SPCS2 (signal peptidase complex subunit 2)	protein interactions	9789	139	2	19454	49	GPC5,PRKN
4.792e-02	-3.04	MON2 (MON2 homolog, regulator of endosome-to-Golgi trafficking)	protein interactions	23041	139	2	19454	49	PRKN,GJA1
4.792e-02	-3.04	MFN2 (mitofusin 2)	protein interactions	9927	139	2	19454	49	CTBP1,PRKN
4.792e-02	-3.04	DAGKc	smart domains	SM00046	14	1	9717	34	DGKB
4.792e-02	-3.04	LY	smart domains	SM00135	14	1	9717	34	EGF
4.792e-02	-3.04	IBR	smart domains	SM00647	14	1	9717	34	PRKN
4.806e-02	-3.04	PIP3 activates AKT signaling	REACTOME pathways	R-HSA-1257604	125	2	10285	29	FGFR3,EGF
4.827e-02	-3.03	glial cell development	biological process	GO:0021782	128	2	18204	50	GPM6B,ASPA
4.832e-02	-3.03	cardiac myofibril assembly	biological process	GO:0055003	18	1	18204	50	FHOD3
4.832e-02	-3.03	positive regulation of circadian rhythm	biological process	GO:0042753	18	1	18204	50	RORA
4.832e-02	-3.03	regulation of dopamine metabolic process	biological process	GO:0042053	18	1	18204	50	PRKN
4.832e-02	-3.03	regulation of catecholamine metabolic process	biological process	GO:0042069	18	1	18204	50	PRKN
4.832e-02	-3.03	hippo signaling	biological process	GO:0035329	18	1	18204	50	AMOT
4.832e-02	-3.03	neuron projection arborization	biological process	GO:0140058	18	1	18204	50	PTN
4.832e-02	-3.03	response to manganese ion	biological process	GO:0010042	18	1	18204	50	PRKN
4.844e-02	-3.03	CTNNA1 (catenin alpha 1)	protein interactions	1495	325	3	19454	49	PRKN,NHSL1,CTBP1
4.848e-02	-3.03	BCAR1 (BCAR1 scaffold protein, Cas family member)	protein interactions	9564	547	4	19454	49	PLPP3,TNS3,FGFR3,BCAR3
4.853e-02	-3.03	AP3D1 (adaptor related protein complex 3 subunit delta 1)	protein interactions	8943	140	2	19454	49	PRKN,GRK5
4.853e-02	-3.03	PALM2AKAP2 (PALM2 and AKAP2 fusion)	protein interactions	445815	140	2	19454	49	PRKN,GJA1
4.853e-02	-3.03	BCCIP (BRCA2 and CDKN1A interacting protein)	protein interactions	56647	140	2	19454	49	PRKN,PTN
4.853e-02	-3.03	STEAP3 (STEAP3 metalloreductase)	protein interactions	55240	140	2	19454	49	PRKN,GJA1
4.853e-02	-3.03	SERPINA1 (serpin family A member 1)	protein interactions	5265	140	2	19454	49	APOA1,PRKN
4.853e-02	-3.03	SATB2 (SATB homeobox 2)	protein interactions	23314	140	2	19454	49	SOX5,NFIA
4.853e-02	-3.03	RAB3GAP2 (RAB3 GTPase activating non-catalytic protein subunit 2)	protein interactions	25782	140	2	19454	49	PRKN,FGFR3
4.857e-02	-3.02	lung-carcinoma-squamous_cell_carcinoma	COSMIC cancer mutations	lung-carcinoma-squamous_cell_carcinoma	14664	45	16828	47	LRIG1,DGKB,TRPS1,SNTB1,SLC4A4,SOX5,FGFRL1,SLC6A11,NPAS3,AMOT,ASPA,SORCS2,FHOD3,SLC1A2,ELOVL2,FGFR3,LAMA4,PREX1,ZBTB20,FKBP5,UNC93A,NHSL1,NCKAP5,QKI,GJA1,AQP4,EGF,GRK5,SLC39A12,USP6NL,SLC1A3,GPC5,TNS3,PTPRZ1,CTBP1,RFX4,LPIN2,MSI2,NFIA,PREX2,PRDM16,FARP1,RORA,PTN,BCAR3
4.863e-02	-3.02	Phosphatidic acid phosphatase type 2/haloperoxidase	gene3d domains	1.20.144.10	18	1	14470	40	PLPP3
4.863e-02	-3.02	-	gene3d domains	3.10.50.40	18	1	14470	40	FKBP5
4.866e-02	-3.02	EWSR1 (EWS RNA binding protein 1)	protein interactions	2130	794	5	19454	49	CTBP1,QKI,SOX5,AMOT,PRKN
4.880e-02	-3.02	PXN (paxillin)	protein interactions	5829	326	3	19454	49	TNS3,PRKN,BCAR3
4.880e-02	-3.02	MRPS27 (mitochondrial ribosomal protein S27)	protein interactions	23107	326	3	19454	49	GRK5,PRKN,FGFR3
4.880e-02	-3.02	DTX2 (deltex E3 ubiquitin ligase 2)	protein interactions	113878	326	3	19454	49	USP6NL,CTBP1,NFIA
4.911e-02	-3.01	sequence-specific double-stranded DNA binding	molecular function	GO:1990837	1547	8	18094	48	RFX4,SOX5,TRPS1,RORA,PRDM16,NPAS3,ZBTB20,NFIA
4.912e-02	-3.01	NS-mesothelioma	COSMIC cancer mutations	NS-mesothelioma	18	1	16828	47	FGFR3
4.916e-02	-3.01	PLK4 (polo like kinase 4)	protein interactions	10733	141	2	19454	49	PRDM16,GJA1
4.916e-02	-3.01	MAPK7 (mitogen-activated protein kinase 7)	protein interactions	5598	141	2	19454	49	FKBP5,GJA1
4.917e-02	-3.01	ROR2 (receptor tyrosine kinase like orphan receptor 2)	protein interactions	4920	327	3	19454	49	SNTB1,GJA1,USP6NL
4.921e-02	-3.01	PCMTD1 (protein-L-isoaspartate (D-aspartate) O-methyltransferase domain containing 1)	protein interactions	115294	20	1	19454	49	PRKN
4.921e-02	-3.01	DDIT4 (DNA damage inducible transcript 4)	protein interactions	54541	20	1	19454	49	PRKN
4.921e-02	-3.01	TOR4A (torsin family 4 member A)	protein interactions	54863	20	1	19454	49	GRK5
4.921e-02	-3.01	SNCB (synuclein beta)	protein interactions	6620	20	1	19454	49	GRK5
4.921e-02	-3.01	CCDC87 (coiled-coil domain containing 87)	protein interactions	55231	20	1	19454	49	PRKN
4.921e-02	-3.01	ADRA1D (adrenoceptor alpha 1D)	protein interactions	146	20	1	19454	49	SNTB1
4.921e-02	-3.01	ADAMTS17 (ADAM metallopeptidase with thrombospondin type 1 motif 17)	protein interactions	170691	20	1	19454	49	PRKN
4.921e-02	-3.01	OXT (oxytocin/neurophysin I prepropeptide)	protein interactions	5020	20	1	19454	49	FGFR3
4.921e-02	-3.01	SERPINA4 (serpin family A member 4)	protein interactions	5267	20	1	19454	49	CTBP1
4.921e-02	-3.01	MON1B (MON1 homolog B, secretory trafficking associated)	protein interactions	22879	20	1	19454	49	PRKN
4.921e-02	-3.01	TTC38 (tetratricopeptide repeat domain 38)	protein interactions	55020	20	1	19454	49	PRKN
4.921e-02	-3.01	SDK1 (sidekick cell adhesion molecule 1)	protein interactions	221935	20	1	19454	49	GJA1
4.921e-02	-3.01	LMCD1 (LIM and cysteine rich domains 1)	protein interactions	29995	20	1	19454	49	PRKN
4.921e-02	-3.01	Pspc1 (paraspeckle protein 1)	protein interactions	66645	20	1	19454	49	CTBP1
4.921e-02	-3.01	CPA5 (carboxypeptidase A5)	protein interactions	93979	20	1	19454	49	PRKN
4.921e-02	-3.01	PDLIM2 (PDZ and LIM domain 2)	protein interactions	64236	20	1	19454	49	BCAR3
4.921e-02	-3.01	RIPOR1 (RHO family interacting cell polarization regulator 1)	protein interactions	79567	20	1	19454	49	PRKN
4.921e-02	-3.01	FNDC1 (fibronectin type III domain containing 1)	protein interactions	84624	20	1	19454	49	APOA1
4.921e-02	-3.01	FAM228A (family with sequence similarity 228 member A)	protein interactions	653140	20	1	19454	49	PRKN
4.921e-02	-3.01	FNIP2 (folliculin interacting protein 2)	protein interactions	57600	20	1	19454	49	PRKN
4.921e-02	-3.01	ANXA13 (annexin A13)	protein interactions	312	20	1	19454	49	MSI2
4.921e-02	-3.01	GJA3 (gap junction protein alpha 3)	protein interactions	2700	20	1	19454	49	GJA1
4.921e-02	-3.01	ATG9B (autophagy related 9B)	protein interactions	285973	20	1	19454	49	PRKN
4.921e-02	-3.01	Trappc8 (trafficking protein particle complex 8)	protein interactions	75964	20	1	19454	49	FARP1
4.921e-02	-3.01	CYP3A43 (cytochrome P450 family 3 subfamily A member 43)	protein interactions	64816	20	1	19454	49	PRKN
4.921e-02	-3.01	CCDC158 (coiled-coil domain containing 158)	protein interactions	339965	20	1	19454	49	PRKN
4.921e-02	-3.01	LBP (lipopolysaccharide binding protein)	protein interactions	3929	20	1	19454	49	APOA1
4.921e-02	-3.01	HDDC2 (HD domain containing 2)	protein interactions	51020	20	1	19454	49	PRKN
4.921e-02	-3.01	PON1 (paraoxonase 1)	protein interactions	5444	20	1	19454	49	APOA1
4.923e-02	-3.01	regulation of epithelial cell migration	biological process	GO:0010632	300	3	18204	50	PTN,PLPP3,EGF
4.924e-02	-3.01	water transmembrane transporter activity	molecular function	GO:0005372	19	1	18094	48	AQP4
4.924e-02	-3.01	secondary active monocarboxylate transmembrane transporter activity	molecular function	GO:0015355	19	1	18094	48	SLC6A11
4.932e-02	-3.01	acute_myeloid_leukaemia	COSMIC cancer mutations	acute_myeloid_leukaemia	10418	35	16828	47	BCAR3,QKI,NCKAP5,NHSL1,UNC93A,RORA,FKBP5,FARP1,PREX1,PRDM16,LAMA4,ELOVL2,SLC1A2,PREX2,NFIA,FHOD3,SORCS2,MSI2,AMOT,RFX4,LPIN2,NPAS3,PTPRZ1,TNS3,GPC5,SLC6A11,SLC1A3,USP6NL,SOX5,SLC39A12,SLC4A4,GRK5,EGF,DGKB,LRIG1
4.932e-02	-3.01	haematopoietic_and_lymphoid_tissue-haematopoietic_neoplasm-acute_myeloid_leukaemia	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue-haematopoietic_neoplasm-acute_myeloid_leukaemia	10418	35	16828	47	SOX5,SLC39A12,SLC4A4,GRK5,EGF,LRIG1,DGKB,SORCS2,MSI2,LPIN2,RFX4,AMOT,PTPRZ1,NPAS3,GPC5,TNS3,SLC6A11,USP6NL,SLC1A3,LAMA4,PREX1,PRDM16,ELOVL2,SLC1A2,NFIA,PREX2,FHOD3,BCAR3,NCKAP5,QKI,NHSL1,UNC93A,RORA,FKBP5,FARP1
4.941e-02	-3.01	LRR_4	pfam domains	PF12799	18	1	17795	50	LRIG1
4.941e-02	-3.01	PAP2	pfam domains	PF01569	18	1	17795	50	PLPP3
4.944e-02	-3.01	Regulation of lipid metabolism by Peroxisome proliferator-activated receptor alpha (PPARalpha)	REACTOME pathways	R-HSA-400206	127	2	10285	29	RORA,APOA1
4.954e-02	-3.01	CPSF7 (cleavage and polyadenylation specific factor 7)	protein interactions	79869	328	3	19454	49	QKI,CTBP1,PRKN
4.954e-02	-3.01	SLIRP (SRA stem-loop interacting RNA binding protein)	protein interactions	81892	328	3	19454	49	PRKN,LAMA4,AMOT
4.960e-02	-3.00	PI-3K cascade:FGFR3	REACTOME pathways	R-HSA-5654710	18	1	10285	29	FGFR3
4.960e-02	-3.00	ABC transporters in lipid homeostasis	REACTOME pathways	R-HSA-1369062	18	1	10285	29	APOA1
4.960e-02	-3.00	SHC-mediated cascade:FGFR3	REACTOME pathways	R-HSA-5654704	18	1	10285	29	FGFR3
4.968e-02	-3.00	thyroid-carcinoma	COSMIC cancer mutations	thyroid-carcinoma	4126	17	16828	47	UNC93A,GPC5,FARP1,AQP4,CTBP1,PTPRZ1,BCAR3,FHOD3,TRPS1,GPM6B,NFIA,LRIG1,FGFR3,PREX1,PRDM16,SOX5,LAMA4
4.978e-02	-3.00	SREBF1 (sterol regulatory element binding transcription factor 1)	protein interactions	6720	142	2	19454	49	PRKN,EGF
4.979e-02	-3.00	vesicle	cellular component	GO:0031982	4141	16	19108	49	SLC1A2,SLC39A12,AMOT,EGF,FKBP5,FGFRL1,AQP4,SLC4A4,GJA1,APOA1,FGFR3,LAMA4,SLC1A3,PRKN,SORCS2,USP6NL
4.999e-02	-3.00	regulation of biological quality	biological process	GO:0065008	2936	13	18204	50	FARP1,ADGRB3,QKI,SLC4A4,DGKB,AQP4,PTN,PLPP3,GJA1,APOA1,PRKN,PREX1,SORCS2