Gene Ontology Enrichment Results

Homer de novo Motif Enrichment Results
Known Motif Enrichment Results

Text file version of complete results (i.e. open with Excel)

biological process: Functional groupings of proteins (Gene Ontology)

molecular function: Mechanistic actions of proteins (Gene Ontology)

cellular component: Protein localization (Gene Ontology)

chromosome location: Genes with similar chromosome localization (NCBI Gene)

KEGG pathways: Groups of proteins in the same pathways (KEGG)

protein interactions: "Proteins interacting with a common protein (BIND, EcoCyc, HPRD)" (NCBI Gene)

interpro domains: Proteins with similar domains and features (Interpro)

pfam domains: Proteins with similar domains and features (Pfam)

smart domains: Proteins with similar domains and features (SMART)

gene3d domains: Proteins with similar domains and features (Gene3D)

prosite domains: Proteins with similar domains and features (Prosite)

prints domains: Proteins with similar domains and features (PRINTS)

MSigDB lists: "Genes sets for pathways, factor/miRNA target predictions, expression patterns, etc." (MSigDB)

BIOCYC pathways: Groups of proteins in the same pathways (BIOCYC)

COSMIC cancer mutations: Genes mutated in similar cancers (COSMIC)

GWAS genes: Genes mutated in similar diseases (GWAS Catalog)

Lipid Maps pathways: Groups of proteins in the same lipid pathways (Lipid Maps/Biosystems)

Pathway Interaction DB: Groups of proteins in the same pathways (Pathway Interaction Database)

REACTOME pathways: Groups of proteins in the same pathways (REACTOME)

SMPDB pathways: Groups of proteins in the same pathways (SMPDB)

WikiPathways: Groups of proteins in the same pathways (Wikipathways)

Enriched Categories

P-value	ln(P)	Term	GO Tree	GO ID	# of Genes in Term	# of Target Genes in Term	# of Total Genes	# of Target Genes	Common Genes
2.645e-08	-17.45	signal transduction	biological process	GO:0007165	4637	31	18204	49	GAB1,P2RY6,ZFP36L1,CSF3R,CD74,RASGRP2,HCK,UNC93B1,DOCK2,MLKL,DAPP1,PLXND1,ELMO1,RXRA,ITGAX,MARCO,ABR,PLEK,SNX17,THRB,SH2B3,MAP3K11,PREX1,ITGB2,RAC2,FYB1,PSAP,CYFIP1,INPP5D,CSF1R,PLXNC1
1.480e-07	-15.73	signaling	biological process	GO:0023052	4968	31	18204	49	CYFIP1,CSF1R,INPP5D,PLXNC1,SNX17,ABR,PLEK,THRB,RAC2,FYB1,PREX1,ITGB2,MAP3K11,SH2B3,PSAP,DOCK2,DAPP1,PLXND1,MLKL,RXRA,ELMO1,MARCO,ITGAX,CD74,ZFP36L1,CSF3R,P2RY6,GAB1,RASGRP2,UNC93B1,HCK
1.605e-07	-15.64	plasma membrane	cellular component	GO:0005886	5538	31	19108	47	MARCO,P2RY6,RASGRP2,CSF1R,ITGAX,CD68,SMPD4,CMTM6,FYB1,PLXNC1,CSF3R,ITGB2,PLEK,HCK,PLXND1,MLKL,VMP1,PSAP,PREX1,RAC2,DAPP1,DOCK2,SH2B3,MYO1F,ELMO1,ITM2B,SLCO2B1,INPP5D,NCAM2,ENTPD1,CD74
1.821e-07	-15.52	cell communication	biological process	GO:0007154	5010	31	18204	49	PLXNC1,INPP5D,CSF1R,CYFIP1,PSAP,MAP3K11,SH2B3,FYB1,RAC2,PREX1,ITGB2,THRB,PLEK,ABR,SNX17,ITGAX,MARCO,ELMO1,RXRA,DAPP1,PLXND1,MLKL,DOCK2,UNC93B1,HCK,RASGRP2,CSF3R,ZFP36L1,GAB1,P2RY6,CD74
7.389e-07	-14.12	cellular response to stimulus	biological process	GO:0051716	6307	34	18204	49	MARCO,SLCO2B1,ITGAX,ELMO1,RXRA,CD68,DAPP1,PLXND1,MLKL,DOCK2,HCK,UNC93B1,RASGRP2,CD74,ZFP36L1,CSF3R,P2RY6,GAB1,PLXNC1,CSF1R,INPP5D,SMPD4,CYFIP1,PSAP,RAC2,FYB1,PREX1,ITGB2,MAP3K11,SH2B3,THRB,SNX17,ABR,PLEK
7.874e-07	-14.05	response to stimulus	biological process	GO:0050896	7803	38	18204	49	P2RY6,GAB1,CSF3R,ZFP36L1,CD74,TNFAIP8L2,UNC93B1,ENTPD1,HCK,RASGRP2,MLKL,PLXND1,DAPP1,CD68,DOCK2,SLCO2B1,ITGAX,MARCO,RXRA,ELMO1,MFNG,THRB,PLEK,ABR,SNX17,PSAP,SH2B3,MAP3K11,ITGB2,PREX1,FYB1,RAC2,CPN1,SMPD4,INPP5D,CSF1R,CYFIP1,PLXNC1
9.747e-07	-13.84	INPP5D (inositol polyphosphate-5-phosphatase D)	protein interactions	3635	70	5	19454	50	HCK,CSF3R,CSF1R,INPP5D,GAB1
1.242e-06	-13.60	cell periphery	cellular component	GO:0071944	6020	31	19108	47	ITGAX,CSF1R,RASGRP2,MARCO,P2RY6,PSAP,PREX1,HCK,PLXND1,MLKL,VMP1,FYB1,ITGB2,CSF3R,PLXNC1,PLEK,CD68,SMPD4,CMTM6,INPP5D,ELMO1,ITM2B,SLCO2B1,DAPP1,SH2B3,MYO1F,DOCK2,RAC2,CD74,NCAM2,ENTPD1
1.899e-06	-13.17	regulation of cell shape	biological process	GO:0008360	139	6	18204	49	CYFIP1,ITGB2,PLXND1,PLXNC1,CSF1R,HCK
3.248e-06	-12.64	Nef and signal transduction	REACTOME pathways	R-HSA-164944	8	3	10285	41	ELMO1,HCK,DOCK2
4.205e-06	-12.38	membrane	cellular component	GO:0016020	9220	38	19108	47	RASGRP2,P2RY6,MARCO,ITGAX,CSF1R,PLEK,MFNG,ITGB2,CSF3R,PLXNC1,FYB1,CMTM6,SMPD4,CD68,PREX1,PSAP,RMC1,VMP1,MLKL,HCK,PLXND1,ADAM33,MYO1F,DOCK2,SH2B3,MAP3K11,UNC93B1,DAPP1,RAC2,SNX17,ABR,INPP5D,SLCO2B1,ELMO1,ITM2B,ENTPD1,NCAM2,CD74
5.827e-06	-12.05	integrin-mediated signaling pathway	biological process	GO:0007229	96	5	18204	49	ITGB2,FYB1,PLEK,HCK,ITGAX
5.922e-06	-12.04	integrin alphaX-beta2 complex	cellular component	GO:0034689	2	2	19108	47	ITGB2,ITGAX
6.230e-06	-11.99	receptor complex	cellular component	GO:0043235	409	8	19108	47	CD74,RXRA,ITGAX,CSF1R,PLXND1,PLXNC1,CSF3R,ITGB2
6.866e-06	-11.89	PH_domain	interpro domains	IPR001849	266	7	18521	50	SH2B3,PLEK,DAPP1,ABR,ELMO1,GAB1,PREX1
7.098e-06	-11.86	positive regulation of thyroid hormone mediated signaling pathway	biological process	GO:0002157	2	2	18204	49	RXRA,THRB
8.978e-06	-11.62	immune system process	biological process	GO:0002376	1991	17	18204	49	MARCO,DOCK2,INPP5D,CSF1R,CD68,SH2B3,PREX1,ITGB2,RAC2,FYB1,TNFAIP8L2,HCK,UNC93B1,ZFP36L1,CSF3R,CD74,MFNG
1.204e-05	-11.33	hemopoiesis	biological process	GO:0030097	688	10	18204	49	CD74,DOCK2,ZFP36L1,PLEK,CSF1R,MFNG,PREX1,RAC2,SH2B3,RBM47
1.837e-05	-10.90	PH-like_dom_sf	interpro domains	IPR011993	431	8	18521	50	SH2B3,PLEK,DAPP1,ABR,SNX17,GAB1,ELMO1,PREX1
2.023e-05	-10.81	regulation of monocyte differentiation	biological process	GO:0045655	20	3	18204	49	INPP5D,CD74,ZFP36L1
3.047e-05	-10.40	cytoplasmic vesicle membrane	cellular component	GO:0030659	1230	12	19108	47	RAC2,MARCO,SNX17,ITM2B,ITGAX,ITGB2,CSF3R,CMTM6,CD68,CD74,PSAP,RMC1
3.199e-05	-10.35	cell adhesion	biological process	GO:0007155	942	11	18204	49	HCK,ENTPD1,ITGB2,RAC2,VMP1,CSF3R,ZFP36L1,PLEK,ITGAX,PLXNC1,NCAM2
3.570e-05	-10.24	vacuole	cellular component	GO:0005773	857	10	19108	47	CD68,CMTM6,UNC93B1,CSF3R,HCK,VMP1,TNFAIP8L2,RMC1,CD74,PSAP
3.601e-05	-10.23	vesicle membrane	cellular component	GO:0012506	1251	12	19108	47	CSF3R,ITGB2,CD68,CMTM6,RMC1,PSAP,CD74,MARCO,RAC2,SNX17,ITGAX,ITM2B
3.907e-05	-10.15	cell surface receptor signaling pathway	biological process	GO:0007166	1992	16	18204	49	P2RY6,GAB1,PLEK,CSF3R,CD74,SH2B3,ITGB2,FYB1,HCK,PLXND1,INPP5D,MLKL,CSF1R,ITGAX,PLXNC1,MARCO
4.012e-05	-10.12	Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)	gene3d domains	2.30.29.30	431	8	14470	44	ELMO1,PREX1,ABR,DAPP1,SH2B3,PLEK,GAB1,SNX17
4.047e-05	-10.11	bounding membrane of organelle	cellular component	GO:0098588	2198	16	19108	47	SNX17,ITGAX,ITM2B,UNC93B1,MARCO,RAC2,RMC1,PSAP,CD74,VMP1,CSF3R,ITGB2,MFNG,CD68,SMPD4,CMTM6
4.233e-05	-10.07	regulation of molecular function	biological process	GO:0065009	2005	16	18204	49	CSF1R,PLXND1,RXRA,SPOCK3,PLXNC1,CD74,VMP1,P2RY6,PLEK,ABR,PREX1,ITGB2,RASGRP2,MAP3K11,PSAP,HCK
4.562e-05	-10.00	ruffle organization	biological process	GO:0031529	26	3	18204	49	CSF1R,PLEK,CYFIP1
4.926e-05	-9.92	regulation of cell morphogenesis	biological process	GO:0022604	246	6	18204	49	PLXNC1,PLXND1,HCK,CSF1R,CYFIP1,ITGB2
5.057e-05	-9.89	endocytosis	biological process	GO:0006897	499	8	18204	49	P2RY6,SNX17,DOCK2,MYO1F,HCK,MARCO,ELMO1,ITGB2
5.420e-05	-9.82	SH3 Domains	gene3d domains	2.30.30.40	223	6	14470	44	DOCK2,FYB1,MYO1F,MAP3K11,HCK,ELMO1
5.629e-05	-9.78	positive regulation of molecular function	biological process	GO:0044093	1192	12	18204	49	CSF1R,ABR,PLEK,P2RY6,VMP1,CD74,PSAP,MAP3K11,RXRA,ITGB2,PREX1,RASGRP2
5.731e-05	-9.77	regulation of catalytic activity	biological process	GO:0050790	1395	13	18204	49	CSF1R,PLXND1,SPOCK3,PLXNC1,CD74,PLEK,ABR,P2RY6,PSAP,PREX1,ITGB2,RASGRP2,MAP3K11
6.176e-05	-9.69	CSF3R (colony stimulating factor 3 receptor)	protein interactions	1441	30	3	19454	50	INPP5D,CSF3R,HCK
6.416e-05	-9.65	small GTPase-mediated signal transduction	biological process	GO:0007264	258	6	18204	49	DOCK2,ABR,CYFIP1,RASGRP2,ELMO1,RAC2
6.674e-05	-9.61	phagocytosis	biological process	GO:0006909	159	5	18204	49	P2RY6,ELMO1,ITGB2,HCK,MARCO
6.895e-05	-9.58	lymph_node	COSMIC cancer mutations	lymph_node	1703	14	16828	44	ELMO1,SPOCK3,HCK,DPYD,DAPP1,CSF1R,ZFP36L1,CD74,MLKL,MAP3K11,CPN1,NCAM2,VMP1,DOCK2
8.117e-05	-9.42	response to external stimulus	biological process	GO:0009605	1882	15	18204	49	GAB1,CSF3R,CD74,ITGB2,PREX1,RAC2,TNFAIP8L2,HCK,UNC93B1,DOCK2,MLKL,CSF1R,CD68,ITGAX,MARCO
8.491e-05	-9.37	lysosome	cellular component	GO:0005764	762	9	19108	47	HCK,CD74,PSAP,TNFAIP8L2,RMC1,CMTM6,CD68,CSF3R,UNC93B1
8.491e-05	-9.37	lytic vacuole	cellular component	GO:0000323	762	9	19108	47	CMTM6,CD68,CSF3R,UNC93B1,HCK,PSAP,CD74,RMC1,TNFAIP8L2
8.704e-05	-9.35	positive regulation of catalytic activity	biological process	GO:0043085	868	10	18204	49	PSAP,MAP3K11,PREX1,ITGB2,RASGRP2,CSF1R,ABR,PLEK,P2RY6,CD74
8.963e-05	-9.32	carcinoid-endocrine_tumour	COSMIC cancer mutations	carcinoid-endocrine_tumour	7752	33	16828	44	PLXNC1,CSF1R,PSAP,SPOCK3,PREX1,RXRA,ABR,NCAM2,DOCK2,VMP1,CSF3R,THRB,RAC2,SMPD4,GAB1,MFNG,PLEK,ANKRD44,HCK,DPYD,SNX17,MYO1F,PLXND1,ITGAX,SH2B3,ADAM33,ELMO1,CPN1,MAP3K11,MLKL,ZFP36L1,MARCO,ITM2B
9.493e-05	-9.26	cell-cell adhesion	biological process	GO:0098609	546	8	18204	49	VMP1,ZFP36L1,PLEK,NCAM2,ITGB2,RAC2,ENTPD1,ITGAX
9.572e-05	-9.25	Regulation of RAC1 activity	Pathway Interaction DB	rac1_reg_pathway	39	4	2226	15	PREX1,ELMO1,ABR,DOCK2
9.785e-05	-9.23	amyloid-beta binding	molecular function	GO:0001540	89	4	18094	49	ITGB2,CD74,MARCO,ITM2B
1.048e-04	-9.16	HCK (HCK proto-oncogene, Src family tyrosine kinase)	protein interactions	3055	183	5	19454	50	HCK,CSF3R,GAB1,ELMO1,INPP5D
1.084e-04	-9.13	cellular response to chemical stimulus	biological process	GO:0070887	2411	17	18204	49	CYFIP1,CD68,CSF1R,SMPD4,RXRA,SLCO2B1,CD74,ZFP36L1,CSF3R,P2RY6,GAB1,THRB,PREX1,RASGRP2,ITGB2,SH2B3,HCK
1.179e-04	-9.05	cell activation	biological process	GO:0001775	725	9	18204	49	TNFAIP8L2,ENTPD1,ITGB2,PREX1,MFNG,PLEK,ZFP36L1,DOCK2,CD74
1.191e-04	-9.04	regulation of hydrolase activity	biological process	GO:0051336	726	9	18204	49	PLXNC1,PSAP,SPOCK3,RASGRP2,PREX1,PLXND1,PLEK,ABR,P2RY6
1.229e-04	-9.00	phagocytosis, engulfment	biological process	GO:0006911	36	3	18204	49	ITGB2,ELMO1,MARCO
1.246e-04	-8.99	intracellular signal transduction	biological process	GO:0035556	1505	13	18204	49	PREX1,RASGRP2,RAC2,SH2B3,MAP3K11,HCK,ABR,ZFP36L1,PLEK,ELMO1,DOCK2,CYFIP1,INPP5D
1.297e-04	-8.95	Chemokine signaling pathway	KEGG pathways	hsa04062	182	6	7161	32	ELMO1,DOCK2,RAC2,RASGRP2,HCK,PREX1
1.297e-04	-8.95	Chemokine signaling pathway	KEGG pathways	ko04062	182	6	7161	32	RASGRP2,HCK,PREX1,ELMO1,DOCK2,RAC2
1.408e-04	-8.87	Hemostasis	REACTOME pathways	R-HSA-109582	632	10	10285	41	ITGAX,RAC2,PLEK,DOCK2,SH2B3,PSAP,ITGB2,RASGRP2,CD74,INPP5D
1.478e-04	-8.82	regulation of thyroid hormone mediated signaling pathway	biological process	GO:0002155	7	2	18204	49	THRB,RXRA
1.525e-04	-8.79	TRIP10 (thyroid hormone receptor interactor 10)	protein interactions	9322	105	4	19454	50	THRB,RXRA,CYFIP1,INPP5D
1.554e-04	-8.77	bone-Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour	COSMIC cancer mutations	bone-Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour	6023	28	16828	44	MFNG,GAB1,CSF3R,DOCK2,ABR,PREX1,DAPP1,PSAP,CSF1R,PLXNC1,MARCO,CD68,ZFP36L1,MAP3K11,MLKL,CPN1,SLCO2B1,ELMO1,ADAM33,ITGAX,PLXND1,SNX17,MYO1F,DPYD,HCK,ENTPD1,ANKRD44,P2RY6
1.638e-04	-8.72	SH2	pfam domains	PF00017	100	4	17795	49	DAPP1,SH2B3,HCK,INPP5D
1.675e-04	-8.69	Immune System	REACTOME pathways	R-HSA-168256	2101	19	10285	41	ITGB2,CD68,CSF1R,CSF3R,DAPP1,ITGAX,DOCK2,FYB1,CD74,HCK,RASGRP2,CYFIP1,GAB1,INPP5D,MAP3K11,ELMO1,CMTM6,UNC93B1,PSAP
1.750e-04	-8.65	SRC (SRC proto-oncogene, non-receptor tyrosine kinase)	protein interactions	6714	624	8	19454	50	FYB1,CYFIP1,GAB1,RXRA,CSF1R,THRB,DAPP1,HCK
1.802e-04	-8.62	nef (Nef)	protein interactions	156110	802	9	19454	50	CD74,ELMO1,RAC2,DOCK2,RXRA,ITGAX,CSF1R,PSAP,HCK
1.808e-04	-8.62	vacuolar membrane	cellular component	GO:0005774	490	7	19108	47	CD68,CMTM6,CSF3R,VMP1,RMC1,CD74,PSAP
1.824e-04	-8.61	KIT (KIT proto-oncogene, receptor tyrosine kinase)	protein interactions	3815	110	4	19454	50	CSF1R,INPP5D,SH2B3,HCK
1.847e-04	-8.60	positive regulation of response to stimulus	biological process	GO:0048584	2266	16	18204	49	RXRA,RBM47,MARCO,CYFIP1,CSF1R,INPP5D,RAC2,FYB1,ITGB2,MAP3K11,HCK,UNC93B1,CD74,P2RY6,MFNG,THRB
1.973e-04	-8.53	PSI	interpro domains	IPR016201	42	3	18521	50	ITGB2,PLXNC1,PLXND1
1.999e-04	-8.52	The role of Nef in HIV-1 replication and disease pathogenesis	REACTOME pathways	R-HSA-164952	29	3	10285	41	ELMO1,DOCK2,HCK
2.007e-04	-8.51	SH2DOMAIN	prints domains	PR00401	72	4	5227	22	DAPP1,INPP5D,HCK,SH2B3
2.039e-04	-8.50	CRKL (CRK like proto-oncogene, adaptor protein)	protein interactions	1399	211	5	19454	50	GAB1,ELMO1,DOCK2,INPP5D,HCK
2.081e-04	-8.48	regulation of immune system process	biological process	GO:0002682	1584	13	18204	49	CD68,CSF1R,INPP5D,CD74,ZFP36L1,CSF3R,HCK,UNC93B1,RBM47,TNFAIP8L2,RAC2,FYB1,ITGB2
2.093e-04	-8.47	MTOR (mechanistic target of rapamycin kinase)	protein interactions	2475	335	6	19454	50	VMP1,CD74,RAC2,UNC93B1,P2RY6,PREX1
2.113e-04	-8.46	cytoplasmic vesicle	cellular component	GO:0031410	2521	16	19108	47	CD74,PSAP,RMC1,HCK,CYFIP1,ITGB2,CSF3R,CMTM6,CD68,SNX17,ITM2B,ITGAX,DOCK2,UNC93B1,RAC2,MARCO
2.122e-04	-8.46	SH2	interpro domains	IPR000980	109	4	18521	50	INPP5D,DAPP1,HCK,SH2B3
2.173e-04	-8.43	intracellular vesicle	cellular component	GO:0097708	2527	16	19108	47	UNC93B1,DOCK2,MARCO,RAC2,SNX17,ITGAX,ITM2B,CSF3R,ITGB2,CD68,CMTM6,RMC1,PSAP,CD74,HCK,CYFIP1
2.194e-04	-8.42	pancreas-carcinoid-endocrine_tumour	COSMIC cancer mutations	pancreas-carcinoid-endocrine_tumour	7250	31	16828	44	ZFP36L1,ITM2B,MARCO,MLKL,CPN1,ELMO1,ADAM33,ITGAX,SH2B3,DPYD,PLXND1,MYO1F,SNX17,ANKRD44,PLEK,SMPD4,RAC2,GAB1,MFNG,CSF3R,THRB,NCAM2,DOCK2,VMP1,PREX1,ABR,RXRA,SPOCK3,PLXNC1,PSAP,CSF1R
2.402e-04	-8.33	plasma membrane invagination	biological process	GO:0099024	45	3	18204	49	ITGB2,ELMO1,MARCO
2.430e-04	-8.32	PH	smart domains	SM00233	259	6	9717	34	GAB1,ABR,PREX1,DAPP1,PLEK,SH2B3
2.437e-04	-8.32	SH2_dom_sf	interpro domains	IPR036860	113	4	18521	50	SH2B3,HCK,INPP5D,DAPP1
2.473e-04	-8.31	positive regulation of immune system process	biological process	GO:0002684	986	10	18204	49	ZFP36L1,CD74,INPP5D,CSF1R,ITGB2,RAC2,FYB1,RBM47,UNC93B1,HCK
2.540e-04	-8.28	Plexin_RBD	interpro domains	IPR046800	9	2	18521	50	PLXND1,PLXNC1
2.540e-04	-8.28	Plexin_cytoplasmic_RasGAP_dom	interpro domains	IPR013548	9	2	18521	50	PLXND1,PLXNC1
2.612e-04	-8.25	SH3-like_dom_sf	interpro domains	IPR036028	212	5	18521	50	HCK,FYB1,DOCK2,MYO1F,MAP3K11
2.641e-04	-8.24	Plexin_cytopl	pfam domains	PF08337	9	2	17795	49	PLXNC1,PLXND1
2.641e-04	-8.24	Plexin_RBD	pfam domains	PF20170	9	2	17795	49	PLXND1,PLXNC1
2.765e-04	-8.19	enzyme binding	molecular function	GO:0019899	2086	15	18094	49	RBM47,SH2B3,PLEK,THRB,MLKL,CYFIP1,CSF1R,MAP3K11,CD74,PSAP,DOCK2,ITGAX,PREX1,RXRA,ITGB2
2.875e-04	-8.15	FCER2 (Fc epsilon receptor II)	protein interactions	2208	10	2	19454	50	ITGB2,ITGAX
2.876e-04	-8.15	DOK1 (docking protein 1)	protein interactions	1796	50	3	19454	50	INPP5D,ITGB2,HCK
2.887e-04	-8.15	TM9SF3 (transmembrane 9 superfamily member 3)	protein interactions	56889	124	4	19454	50	P2RY6,RAC2,RBM47,UNC93B1
3.121e-04	-8.07	chemotaxis	biological process	GO:0006935	345	6	18204	49	CSF3R,GAB1,RAC2,DOCK2,ITGB2,PREX1
3.150e-04	-8.06	positive regulation of monocyte differentiation	biological process	GO:0045657	10	2	18204	49	CD74,ZFP36L1
3.170e-04	-8.06	Plexin	interpro domains	IPR031148	10	2	18521	50	PLXND1,PLXNC1
3.219e-04	-8.04	taxis	biological process	GO:0042330	347	6	18204	49	DOCK2,PREX1,ITGB2,RAC2,GAB1,CSF3R
3.231e-04	-8.04	SH3_domain	interpro domains	IPR001452	222	5	18521	50	DOCK2,FYB1,HCK,MYO1F,MAP3K11
3.356e-04	-8.00	EIF2B4 (eukaryotic translation initiation factor 2B subunit delta)	protein interactions	8890	129	4	19454	50	MFNG,P2RY6,CD74,UNC93B1
3.419e-04	-7.98	ELMO2 (engulfment and cell motility 2)	protein interactions	63916	53	3	19454	50	DOCK2,RAC2,ELMO1
3.485e-04	-7.96	regulation of granulocyte chemotaxis	biological process	GO:0071622	51	3	18204	49	CSF1R,CD74,RAC2
3.515e-04	-7.95	SH2 domain	gene3d domains	3.30.505.10	111	4	14470	44	DAPP1,SH2B3,HCK,INPP5D
3.691e-04	-7.90	guanyl-nucleotide exchange factor activity	molecular function	GO:0005085	228	5	18094	49	ELMO1,PREX1,RASGRP2,DOCK2,ABR
3.692e-04	-7.90	membrane invagination	biological process	GO:0010324	52	3	18204	49	MARCO,ITGB2,ELMO1
3.844e-04	-7.86	regulation of dendritic cell antigen processing and presentation	biological process	GO:0002604	11	2	18204	49	CD74,CD68
3.958e-04	-7.83	positive regulation of multicellular organismal process	biological process	GO:0051240	1691	13	18204	49	CD74,ZFP36L1,PLEK,GAB1,UNC93B1,CYFIP1,CSF1R,PLXND1,INPP5D,RXRA,RBM47,PLXNC1,ITGAX
4.094e-04	-7.80	PSI	smart domains	SM00423	42	3	9717	34	ITGB2,PLXND1,PLXNC1
4.117e-04	-7.80	azurophil granule membrane	cellular component	GO:0035577	59	3	19108	47	PSAP,CD68,CMTM6
4.152e-04	-7.79	mononuclear cell differentiation	biological process	GO:1903131	364	6	18204	49	PREX1,CD74,DOCK2,ZFP36L1,CSF1R,MFNG
4.203e-04	-7.77	ROBO4 (roundabout guidance receptor 4)	protein interactions	54538	12	2	19454	50	THRB,RXRA
4.203e-04	-7.77	RWDD1 (RWD domain containing 1)	protein interactions	51389	12	2	19454	50	CD74,P2RY6
4.291e-04	-7.75	MET (MET proto-oncogene, receptor tyrosine kinase)	protein interactions	4233	248	5	19454	50	SH2B3,HCK,ITM2B,INPP5D,GAB1
4.300e-04	-7.75	regulation of response to stimulus	biological process	GO:0048583	4104	22	18204	49	HCK,UNC93B1,TNFAIP8L2,CD74,P2RY6,RXRA,MARCO,DOCK2,PREX1,ITGB2,FYB1,RAC2,SH2B3,MAP3K11,ABR,PLEK,THRB,MFNG,RBM47,CYFIP1,CSF1R,INPP5D
4.301e-04	-7.75	LYN (LYN proto-oncogene, Src family tyrosine kinase)	protein interactions	4067	713	8	19454	50	CSF3R,RAC2,GAB1,INPP5D,CYFIP1,HCK,DAPP1,CSF1R
4.324e-04	-7.75	SH2	smart domains	SM00252	103	4	9717	34	DAPP1,HCK,SH2B3,INPP5D
4.336e-04	-7.74	locomotion	biological process	GO:0040011	367	6	18204	49	DOCK2,GAB1,CSF3R,ITGB2,PREX1,RAC2
4.357e-04	-7.74	neutrophil chemotaxis	biological process	GO:0030593	55	3	18204	49	CSF3R,PREX1,ITGB2
4.467e-04	-7.71	PK_Tyr_Ser-Thr	pfam domains	PF07714	130	4	17795	49	CSF1R,MAP3K11,MLKL,HCK
4.527e-04	-7.70	import into cell	biological process	GO:0098657	687	8	18204	49	P2RY6,DOCK2,MYO1F,SNX17,MARCO,HCK,ITGB2,ELMO1
4.532e-04	-7.70	Ser-Thr/Tyr_kinase_cat_dom	interpro domains	IPR001245	133	4	18521	50	CSF1R,HCK,MLKL,MAP3K11
4.540e-04	-7.70	semaphorin receptor complex	cellular component	GO:0002116	13	2	19108	47	PLXNC1,PLXND1
4.563e-04	-7.69	cellular response to organic substance	biological process	GO:0071310	1716	13	18204	49	SMPD4,CD68,CSF1R,CYFIP1,RXRA,THRB,CSF3R,ZFP36L1,P2RY6,GAB1,CD74,HCK,SH2B3
4.605e-04	-7.68	negative thymic T cell selection	biological process	GO:0045060	12	2	18204	49	DOCK2,CD74
4.605e-04	-7.68	positive thymic T cell selection	biological process	GO:0045059	12	2	18204	49	DOCK2,CD74
4.660e-04	-7.67	semaphorin receptor activity	molecular function	GO:0017154	12	2	18094	49	PLXND1,PLXNC1
4.958e-04	-7.61	TMEM209 (transmembrane protein 209)	protein interactions	84928	143	4	19454	50	RBM47,RAC2,P2RY6,UNC93B1
4.973e-04	-7.61	PIK3R1 (phosphoinositide-3-kinase regulatory subunit 1)	protein interactions	5295	394	6	19454	50	CSF1R,HCK,INPP5D,RAC2,GAB1,RXRA
5.131e-04	-7.58	B Cell Receptor Signaling Pathway	WikiPathways	WP23	98	4	5310	21	DAPP1,RAC2,GAB1,INPP5D
5.137e-04	-7.57	PLCG1 (phospholipase C gamma 1)	protein interactions	5335	258	5	19454	50	GAB1,INPP5D,HCK,DAPP1,SH2B3
5.328e-04	-7.54	SH2	prosite domains	PS50001	107	4	12186	43	DAPP1,SH2B3,HCK,INPP5D
5.432e-04	-7.52	negative T cell selection	biological process	GO:0043383	13	2	18204	49	DOCK2,CD74
5.895e-04	-7.44	immune effector process	biological process	GO:0002252	389	6	18204	49	CD74,DOCK2,INPP5D,MFNG,UNC93B1,HCK
5.960e-04	-7.43	DGKE (diacylglycerol kinase epsilon)	protein interactions	8526	64	3	19454	50	CD74,P2RY6,UNC93B1
6.021e-04	-7.42	skin-scalp-carcinoma-squamous_cell_carcinoma	COSMIC cancer mutations	skin-scalp-carcinoma-squamous_cell_carcinoma	1596	12	16828	44	P2RY6,CSF1R,MYO1F,PLXNC1,DPYD,ITGB2,ITGAX,ELMO1,PREX1,NCAM2,SLCO2B1,RBM47
6.037e-04	-7.41	amide binding	molecular function	GO:0033218	254	5	18094	49	ITM2B,MARCO,CD74,PSAP,ITGB2
6.277e-04	-7.37	haematopoietic_and_lymphoid_tissue-lymph_node-lymphoid_neoplasm-diffuse_large_B_cell_lymphoma	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue-lymph_node-lymphoid_neoplasm-diffuse_large_B_cell_lymphoma	748	8	16828	44	CD74,ELMO1,ZFP36L1,VMP1,CPN1,MLKL,HCK,DPYD
6.293e-04	-7.37	SH3	smart domains	SM00326	202	5	9717	34	DOCK2,MYO1F,HCK,FYB1,MAP3K11
6.381e-04	-7.36	specific granule	cellular component	GO:0042581	160	4	19108	47	ITGB2,DOCK2,CYFIP1,CMTM6
6.411e-04	-7.35	Fc gamma R-mediated phagocytosis	KEGG pathways	ko04666	90	4	7161	32	RAC2,DOCK2,INPP5D,HCK
6.411e-04	-7.35	Fc gamma R-mediated phagocytosis	KEGG pathways	hsa04666	90	4	7161	32	INPP5D,DOCK2,HCK,RAC2
6.479e-04	-7.34	peptide binding	molecular function	GO:0042277	258	5	18094	49	ITGB2,ITM2B,CD74,MARCO,RXRA
6.661e-04	-7.31	scalp	COSMIC cancer mutations	scalp	2110	14	16828	44	RBM47,MARCO,NCAM2,SLCO2B1,ITGB2,ITGAX,ADAM33,ELMO1,PREX1,P2RY6,MYO1F,CSF1R,PLXNC1,DPYD
6.883e-04	-7.28	regulation of cell motility	biological process	GO:2000145	1122	10	18204	49	PLXND1,CSF1R,GAB1,P2RY6,CD74,ITGAX,PLXNC1,SPOCK3,PREX1,RAC2
6.890e-04	-7.28	thyroid-carcinoma	COSMIC cancer mutations	thyroid-carcinoma	4126	21	16828	44	CSF3R,SLCO2B1,NCAM2,VMP1,DOCK2,RBM47,PLEK,CD74,PLXNC1,DPYD,SNX17,PSAP,PLXND1,ANKRD44,PREX1,RXRA,ELMO1,ABR,SPOCK3,SH2B3,ITGAX
7.044e-04	-7.26	PPP6R1 (protein phosphatase 6 regulatory subunit 1)	protein interactions	22870	157	4	19454	50	UNC93B1,ANKRD44,CD74,P2RY6
7.119e-04	-7.25	T cell differentiation in thymus	biological process	GO:0033077	65	3	18204	49	CD74,DOCK2,ZFP36L1
7.288e-04	-7.22	regulation of inositol phosphate biosynthetic process	biological process	GO:0010919	15	2	18204	49	P2RY6,PLEK
7.392e-04	-7.21	regulation of actin polymerization or depolymerization	biological process	GO:0008064	152	4	18204	49	PREX1,CYFIP1,PLEK,HCK
7.444e-04	-7.20	neutrophil migration	biological process	GO:1990266	66	3	18204	49	ITGB2,PREX1,CSF3R
7.466e-04	-7.20	lysosomal membrane	cellular component	GO:0005765	446	6	19108	47	CD68,CMTM6,RMC1,CD74,CSF3R,PSAP
7.466e-04	-7.20	lytic vacuole membrane	cellular component	GO:0098852	446	6	19108	47	CMTM6,CD68,CD74,PSAP,CSF3R,RMC1
7.514e-04	-7.19	immune response	biological process	GO:0006955	1349	11	18204	49	MFNG,CD74,UNC93B1,HCK,TNFAIP8L2,FYB1,CSF1R,CD68,INPP5D,DOCK2,MARCO
7.643e-04	-7.18	anatomical structure development	biological process	GO:0048856	5207	25	18204	49	RXRA,ITGAX,DOCK2,PLXND1,ITM2B,HCK,UNC93B1,VMP1,CD74,CSF3R,ZFP36L1,GAB1,NCAM2,RBM47,CYFIP1,CSF1R,RAC2,ITGB2,PREX1,SH2B3,PSAP,SNX17,PLEK,MFNG,THRB
7.852e-04	-7.15	regulation of multicellular organismal process	biological process	GO:0051239	3113	18	18204	49	RAC2,SH2B3,UNC93B1,TNFAIP8L2,CD74,GAB1,PLEK,ZFP36L1,CSF3R,THRB,RXRA,RBM47,ITGAX,PLXNC1,CYFIP1,CSF1R,PLXND1,INPP5D
7.952e-04	-7.14	regulation of actin filament length	biological process	GO:0030832	155	4	18204	49	HCK,PLEK,CYFIP1,PREX1
8.822e-04	-7.03	regulation of GTPase activity	biological process	GO:0043087	278	5	18204	49	ABR,RASGRP2,PREX1,PLXND1,PLXNC1
8.870e-04	-7.03	EIF2B5 (eukaryotic translation initiation factor 2B subunit epsilon)	protein interactions	8893	167	4	19454	50	UNC93B1,CD68,P2RY6,CD74
9.145e-04	-7.00	regulation of locomotion	biological process	GO:0040012	1164	10	18204	49	CSF1R,PLXND1,CD74,GAB1,P2RY6,SPOCK3,ITGAX,PLXNC1,PREX1,RAC2
9.350e-04	-6.97	leukocyte differentiation	biological process	GO:0002521	425	6	18204	49	DOCK2,PREX1,CD74,ZFP36L1,CSF1R,MFNG
9.407e-04	-6.97	protein trimerization	biological process	GO:0070206	17	2	18204	49	CD74,MLKL
9.458e-04	-6.96	haematopoietic_and_lymphoid_tissue	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue	14368	44	16828	44	RAC2,THRB,VMP1,PREX1,ITGB2,RASGRP2,PLXNC1,DAPP1,CSF1R,CMTM6,CD68,ITM2B,CD74,SLCO2B1,MLKL,CPN1,ELMO1,ADAM33,DPYD,HCK,P2RY6,ENTPD1,PLEK,RBM47,SMPD4,GAB1,MFNG,CSF3R,NCAM2,DOCK2,ABR,RXRA,TNFAIP8L2,SPOCK3,PSAP,ZFP36L1,MARCO,MAP3K11,SH2B3,ITGAX,PLXND1,MYO1F,SNX17,ANKRD44
9.466e-04	-6.96	Thyroglobulin_1_sf	interpro domains	IPR036857	17	2	18521	50	CD74,SPOCK3
9.466e-04	-6.96	Thyroglobulin_1	interpro domains	IPR000716	17	2	18521	50	SPOCK3,CD74
9.738e-04	-6.93	positive regulation of cell migration	biological process	GO:0030335	592	7	18204	49	ITGAX,PREX1,RAC2,CSF1R,GAB1,P2RY6,CD74
9.762e-04	-6.93	response to chemical	biological process	GO:0042221	3743	20	18204	49	CD74,P2RY6,GAB1,ZFP36L1,CSF3R,THRB,RASGRP2,ITGB2,PREX1,RAC2,SH2B3,HCK,DOCK2,CYFIP1,CSF1R,CD68,CPN1,SMPD4,RXRA,SLCO2B1
9.839e-04	-6.92	Thyroglobulin_1	pfam domains	PF00086	17	2	17795	49	CD74,SPOCK3
1.021e-03	-6.89	Innate Immune System	REACTOME pathways	R-HSA-168249	1285	13	10285	41	UNC93B1,CMTM6,PSAP,CYFIP1,GAB1,HCK,RASGRP2,ELMO1,MAP3K11,DOCK2,ITGAX,CD68,ITGB2
1.043e-03	-6.87	leukocyte activation	biological process	GO:0045321	599	7	18204	49	MFNG,TNFAIP8L2,PREX1,ITGB2,DOCK2,CD74,ZFP36L1
1.051e-03	-6.86	SH3	prosite domains	PS50002	222	5	12186	43	MAP3K11,HCK,DOCK2,MYO1F,FYB1
1.055e-03	-6.85	secretory granule membrane	cellular component	GO:0030667	317	5	19108	47	PSAP,ITGB2,CD68,ITGAX,CMTM6
1.056e-03	-6.85	retinoic acid receptor signaling pathway	biological process	GO:0048384	18	2	18204	49	THRB,RXRA
1.065e-03	-6.84	lymphocyte differentiation	biological process	GO:0030098	290	5	18204	49	MFNG,PREX1,DOCK2,CD74,ZFP36L1
1.166e-03	-6.75	positive regulation of axonogenesis	biological process	GO:0050772	77	3	18204	49	CYFIP1,PLXND1,PLXNC1
1.194e-03	-6.73	Thyroglobulin type-1	gene3d domains	4.10.800.10	17	2	14470	44	CD74,SPOCK3
1.195e-03	-6.73	SCAMP3 (secretory carrier membrane protein 3)	protein interactions	10067	181	4	19454	50	UNC93B1,RAC2,P2RY6,RBM47
1.223e-03	-6.71	defense response	biological process	GO:0006952	1431	11	18204	49	ITGB2,HCK,UNC93B1,MARCO,TNFAIP8L2,ITGAX,CD74,CSF3R,CD68,CSF1R,MLKL
1.261e-03	-6.68	positive regulation of cell motility	biological process	GO:2000147	619	7	18204	49	CSF1R,P2RY6,GAB1,CD74,ITGAX,RAC2,PREX1
1.293e-03	-6.65	regulation of cell adhesion	biological process	GO:0030155	807	8	18204	49	CD74,PLXND1,RAC2,ITGB2,PREX1,SH2B3,TNFAIP8L2,PLXNC1
1.307e-03	-6.64	regulation of antigen processing and presentation	biological process	GO:0002577	20	2	18204	49	CD74,CD68
1.314e-03	-6.64	developmental process	biological process	GO:0032502	5716	26	18204	49	MFNG,THRB,PLEK,SNX17,PSAP,SH2B3,ITGB2,PREX1,RAC2,CSF1R,CYFIP1,RBM47,NCAM2,GAB1,CSF3R,ZFP36L1,CD74,VMP1,HCK,UNC93B1,ITM2B,PLXND1,LRMDA,DOCK2,ITGAX,RXRA
1.360e-03	-6.60	WSB2 (WD repeat and SOCS box containing 2)	protein interactions	55884	85	3	19454	50	CSF3R,PREX1,SMPD4
1.367e-03	-6.59	TIG	pfam domains	PF01833	20	2	17795	49	PLXNC1,PLXND1
1.373e-03	-6.59	positive regulation of cell development	biological process	GO:0010720	458	6	18204	49	CD74,CYFIP1,ZFP36L1,PLXND1,INPP5D,PLXNC1
1.396e-03	-6.57	regulation of cell activation	biological process	GO:0050865	630	7	18204	49	INPP5D,TNFAIP8L2,ZFP36L1,PLEK,SH2B3,RAC2,CD74
1.398e-03	-6.57	mucosal	COSMIC cancer mutations	mucosal	2009	13	16828	44	CSF3R,THRB,MLKL,SMPD4,RBM47,MARCO,PLXNC1,HCK,CSF1R,ITGAX,RXRA,ELMO1,ABR
1.398e-03	-6.57	skin-mucosal-malignant_melanoma	COSMIC cancer mutations	skin-mucosal-malignant_melanoma	2009	13	16828	44	ITGAX,ELMO1,ABR,RXRA,HCK,PLXNC1,CSF1R,SMPD4,RBM47,MARCO,CSF3R,MLKL,THRB
1.398e-03	-6.57	granulocyte chemotaxis	biological process	GO:0071621	82	3	18204	49	CSF3R,PREX1,ITGB2
1.432e-03	-6.55	negative regulation of cell adhesion	biological process	GO:0007162	310	5	18204	49	SH2B3,CD74,PLXND1,TNFAIP8L2,PLXNC1
1.432e-03	-6.55	nodular	COSMIC cancer mutations	nodular	1515	11	16828	44	THRB,SLCO2B1,CSF3R,DOCK2,ANKRD44,TNFAIP8L2,RBM47,ADAM33,PLEK,ITGB2,SPOCK3
1.434e-03	-6.55	kidney-carcinoma	COSMIC cancer mutations	kidney-carcinoma	3720	19	16828	44	VMP1,CPN1,THRB,MLKL,MAP3K11,MFNG,GAB1,RAC2,ANKRD44,CSF1R,SNX17,DPYD,HCK,RASGRP2,ITGB2,ITGAX,ADAM33,RXRA,PREX1
1.435e-03	-6.55	positive regulation of locomotion	biological process	GO:0040017	633	7	18204	49	RAC2,PREX1,ITGAX,CD74,GAB1,P2RY6,CSF1R
1.442e-03	-6.54	T cell differentiation	biological process	GO:0030217	182	4	18204	49	ZFP36L1,DOCK2,CD74,PREX1
1.443e-03	-6.54	thymic T cell selection	biological process	GO:0045061	21	2	18204	49	CD74,DOCK2
1.447e-03	-6.54	SLAMF7 (SLAM family member 7)	protein interactions	57823	22	2	19454	50	INPP5D,CMTM6
1.447e-03	-6.54	FCGR2B (Fc gamma receptor IIb)	protein interactions	2213	22	2	19454	50	GAB1,INPP5D
1.450e-03	-6.54	guanyl-nucleotide exchange factor complex	cellular component	GO:0032045	23	2	19108	47	ELMO1,RMC1
1.452e-03	-6.54	GDS_CDC24_CS	interpro domains	IPR001331	21	2	18521	50	ABR,PREX1
1.455e-03	-6.53	PLCG2 (phospholipase C gamma 2)	protein interactions	5336	87	3	19454	50	GAB1,HCK,DAPP1
1.500e-03	-6.50	positive regulation of hydrolase activity	biological process	GO:0051345	466	6	18204	49	PLEK,ABR,P2RY6,RASGRP2,PREX1,PSAP
1.509e-03	-6.50	DEP	pfam domains	PF00610	21	2	17795	49	PLEK,PREX1
1.519e-03	-6.49	skin-trunk-malignant_melanoma-nodular	COSMIC cancer mutations	skin-trunk-malignant_melanoma-nodular	1291	10	16828	44	CSF3R,THRB,ANKRD44,DOCK2,PLEK,TNFAIP8L2,ADAM33,RBM47,SPOCK3,ITGB2
1.528e-03	-6.48	positive regulation of immune response	biological process	GO:0050778	640	7	18204	49	FYB1,ITGB2,CD74,INPP5D,UNC93B1,HCK,RBM47
1.536e-03	-6.48	T cell activation	biological process	GO:0042110	315	5	18204	49	TNFAIP8L2,ZFP36L1,PREX1,CD74,DOCK2
1.543e-03	-6.47	endocytic vesicle membrane	cellular component	GO:0030666	203	4	19108	47	MARCO,RAC2,CSF3R,CD74
1.564e-03	-6.46	TY	smart domains	SM00211	17	2	9717	34	SPOCK3,CD74
1.594e-03	-6.44	DEP_dom	interpro domains	IPR000591	22	2	18521	50	PREX1,PLEK
1.599e-03	-6.44	THYROGLOBULIN_1_2	prosite domains	PS51162	17	2	12186	43	CD74,SPOCK3
1.599e-03	-6.44	THYROGLOBULIN_1_1	prosite domains	PS00484	17	2	12186	43	CD74,SPOCK3
1.604e-03	-6.44	IPO13 (importin 13)	protein interactions	9670	90	3	19454	50	UNC93B1,CD74,P2RY6
1.615e-03	-6.43	endocytic vesicle	cellular component	GO:0030139	349	5	19108	47	RAC2,MARCO,CD74,CSF3R,UNC93B1
1.631e-03	-6.42	intracellular signaling cassette	biological process	GO:0141124	837	8	18204	49	DOCK2,ABR,CYFIP1,ZFP36L1,RASGRP2,RAC2,ELMO1,MAP3K11
1.632e-03	-6.42	TMEM237 (transmembrane protein 237)	protein interactions	65062	197	4	19454	50	RAC2,ADAM33,CMTM6,UNC93B1
1.632e-03	-6.42	molecular transducer activity	molecular function	GO:0060089	1474	11	18094	49	CSF1R,PLXNC1,P2RY6,ITGAX,MARCO,CD74,PLXND1,ITGB2,CSF3R,RXRA,THRB
1.632e-03	-6.42	signaling receptor activity	molecular function	GO:0038023	1474	11	18094	49	PLXND1,CSF3R,ITGB2,THRB,RXRA,PLXNC1,CSF1R,P2RY6,ITGAX,MARCO,CD74
1.655e-03	-6.40	SOS1 (SOS Ras/Rac guanine nucleotide exchange factor 1)	protein interactions	6654	91	3	19454	50	GAB1,CSF1R,HCK
1.657e-03	-6.40	PH_DOMAIN	prosite domains	PS50003	246	5	12186	43	ABR,PLEK,GAB1,PREX1,DAPP1
1.671e-03	-6.39	lymphocyte activation	biological process	GO:0046649	476	6	18204	49	TNFAIP8L2,PREX1,MFNG,ZFP36L1,DOCK2,CD74
1.671e-03	-6.39	central_nervous_system-brain-primitive_neuroectodermal_tumour-medulloblastoma	COSMIC cancer mutations	central_nervous_system-brain-primitive_neuroectodermal_tumour-medulloblastoma	7205	29	16828	44	PREX1,RXRA,ABR,SPOCK3,ITGB2,RASGRP2,PSAP,CMTM6,PLEK,RAC2,SMPD4,GAB1,CSF3R,THRB,NCAM2,DOCK2,VMP1,ADAM33,ELMO1,ITGAX,SH2B3,DPYD,MYO1F,SNX17,ANKRD44,ENTPD1,MARCO,CPN1,MLKL
1.713e-03	-6.37	NRAS (NRAS proto-oncogene, GTPase)	protein interactions	4893	683	7	19454	50	GAB1,CYFIP1,FYB1,ITM2B,PREX1,RASGRP2,THRB
1.723e-03	-6.36	GSTCD (glutathione S-transferase C-terminal domain containing)	protein interactions	79807	24	2	19454	50	DAPP1,CSF1R
1.730e-03	-6.36	PH	pfam domains	PF00169	187	4	17795	49	SH2B3,GAB1,DAPP1,PLEK
1.732e-03	-6.36	amyloid-beta clearance	biological process	GO:0097242	23	2	18204	49	MARCO,ITGB2
1.752e-03	-6.35	response to organic substance	biological process	GO:0010033	2498	15	18204	49	THRB,CD74,GAB1,P2RY6,CSF3R,ZFP36L1,HCK,ITGB2,SH2B3,CSF1R,CD68,CPN1,SMPD4,CYFIP1,RXRA
1.758e-03	-6.34	cell development	biological process	GO:0048468	2236	14	18204	49	RBM47,NCAM2,CSF1R,PLXND1,DOCK2,CYFIP1,RAC2,PREX1,SH2B3,MFNG,THRB,CD74,PLEK,ZFP36L1
1.762e-03	-6.34	C19orf25 (chromosome 19 open reading frame 25)	protein interactions	148223	93	3	19454	50	P2RY6,MFNG,UNC93B1
1.809e-03	-6.31	signaling receptor binding	molecular function	GO:0005102	1493	11	18094	49	MARCO,CD74,HCK,DOCK2,ITGAX,UNC93B1,PLXNC1,SNX17,SH2B3,FYB1,ITGB2
1.844e-03	-6.30	Rho_GTPase_activation_prot	interpro domains	IPR008936	90	3	18521	50	PLXNC1,ABR,PLXND1
1.866e-03	-6.28	regulation of cell migration	biological process	GO:0030334	1061	9	18204	49	PLXND1,CSF1R,P2RY6,GAB1,CD74,PLXNC1,ITGAX,RAC2,PREX1
1.870e-03	-6.28	ADAT3 (adenosine deaminase tRNA specific 3)	protein interactions	113179	25	2	19454	50	ANKRD44,THRB
1.886e-03	-6.27	positive regulation of neutrophil chemotaxis	biological process	GO:0090023	24	2	18204	49	CD74,RAC2
1.886e-03	-6.27	respiratory burst	biological process	GO:0045730	24	2	18204	49	HCK,RAC2
1.888e-03	-6.27	ARCN1 (archain 1)	protein interactions	372	205	4	19454	50	RMC1,UNC93B1,CD74,P2RY6
1.910e-03	-6.26	vesicle-mediated transport	biological process	GO:0016192	1283	10	18204	49	ELMO1,ITGB2,HCK,MARCO,PLEK,CMTM6,P2RY6,SNX17,DOCK2,MYO1F
1.911e-03	-6.26	cell differentiation	biological process	GO:0030154	3645	19	18204	49	RBM47,RXRA,NCAM2,CSF1R,LRMDA,PLXND1,DOCK2,CYFIP1,HCK,PSAP,RAC2,PREX1,ITGB2,SH2B3,THRB,MFNG,CD74,PLEK,ZFP36L1
1.913e-03	-6.26	human chr7p14.2-p14.1	chromosome location	human chr7p14.2-p14.1	1	1	26134	50	ELMO1
1.913e-03	-6.26	human chr10q22.2-q22.3	chromosome location	human chr10q22.2-q22.3	1	1	26134	50	LRMDA
1.931e-03	-6.25	cellular developmental process	biological process	GO:0048869	3648	19	18204	49	HCK,PSAP,RAC2,PREX1,ITGB2,SH2B3,MFNG,THRB,CD74,PLEK,ZFP36L1,RBM47,RXRA,NCAM2,CSF1R,LRMDA,PLXND1,DOCK2,CYFIP1
1.945e-03	-6.24	positive regulation of transporter activity	biological process	GO:0032411	92	3	18204	49	P2RY6,VMP1,RXRA
1.945e-03	-6.24	positive regulation of leukocyte chemotaxis	biological process	GO:0002690	92	3	18204	49	CSF1R,CD74,RAC2
1.987e-03	-6.22	SOCS3 (suppressor of cytokine signaling 3)	protein interactions	9021	97	3	19454	50	CSF3R,CSF1R,GAB1
1.999e-03	-6.22	positive regulation of ERK1 and ERK2 cascade	biological process	GO:0070374	199	4	18204	49	CSF1R,MARCO,CD74,P2RY6
2.023e-03	-6.20	SEMA7A (semaphorin 7A (JohnMiltonHagen blood group))	protein interactions	8482	26	2	19454	50	PLXNC1,UNC93B1
2.025e-03	-6.20	lipid binding	molecular function	GO:0008289	861	8	18094	49	PSAP,HCK,RASGRP2,PREX1,DAPP1,SNX17,FYB1,RXRA
2.027e-03	-6.20	Cell surface interactions at the vascular wall	REACTOME pathways	R-HSA-202733	136	4	10285	41	INPP5D,ITGB2,ITGAX,CD74
2.047e-03	-6.19	Rac protein signal transduction	biological process	GO:0016601	25	2	18204	49	ELMO1,CYFIP1
2.059e-03	-6.19	Integrin_dom_sf	interpro domains	IPR032695	25	2	18521	50	ITGB2,ITGAX
2.074e-03	-6.18	ESYT2 (extended synaptotagmin 2)	protein interactions	57488	353	5	19454	50	UNC93B1,RAC2,P2RY6,VMP1,SMPD4
2.102e-03	-6.16	diffuse_large_B_cell_lymphoma	COSMIC cancer mutations	diffuse_large_B_cell_lymphoma	4151	20	16828	44	ELMO1,ANKRD44,DPYD,HCK,PLXNC1,PSAP,PLXND1,SMPD4,GAB1,CD74,ZFP36L1,ITM2B,MARCO,NCAM2,DOCK2,VMP1,SLCO2B1,MLKL,CPN1,THRB
2.168e-03	-6.13	UMPS (uridine monophosphate synthetase)	protein interactions	7372	100	3	19454	50	VMP1,SNX17,RMC1
2.181e-03	-6.13	MECR (mitochondrial trans-2-enoyl-CoA reductase)	protein interactions	51102	27	2	19454	50	RXRA,THRB
2.183e-03	-6.13	Rap1 signaling pathway	KEGG pathways	hsa04015	210	5	7161	32	FYB1,RAC2,ITGB2,RASGRP2,CSF1R
2.183e-03	-6.13	Rap1 signaling pathway	KEGG pathways	ko04015	210	5	7161	32	RASGRP2,CSF1R,RAC2,FYB1,ITGB2
2.197e-03	-6.12	granulocyte migration	biological process	GO:0097530	96	3	18204	49	PREX1,ITGB2,CSF3R
2.201e-03	-6.12	regulation of actin cytoskeleton organization	biological process	GO:0032956	342	5	18204	49	CYFIP1,PLEK,PREX1,HCK,CSF1R
2.214e-03	-6.11	positive regulation of granulocyte chemotaxis	biological process	GO:0071624	26	2	18204	49	RAC2,CD74
2.228e-03	-6.11	cellular response to hormone stimulus	biological process	GO:0032870	504	6	18204	49	RXRA,THRB,CYFIP1,ZFP36L1,GAB1,P2RY6
2.264e-03	-6.09	Class I PI3K signaling events	Pathway Interaction DB	pi3kcipathway	41	3	2226	15	HCK,DAPP1,PREX1
2.370e-03	-6.05	YES1 (YES proto-oncogene 1, Src family tyrosine kinase)	protein interactions	7525	364	5	19454	50	CYFIP1,CSF1R,RAC2,GAB1,HCK
2.394e-03	-6.03	DEP	smart domains	SM00049	21	2	9717	34	PREX1,PLEK
2.446e-03	-6.01	Farnesoid X Receptor Pathway	WikiPathways	WP2879	19	2	5310	21	SLCO2B1,RXRA
2.448e-03	-6.01	DEP	prosite domains	PS50186	21	2	12186	43	PREX1,PLEK
2.448e-03	-6.01	DH_1	prosite domains	PS00741	21	2	12186	43	PREX1,ABR
2.460e-03	-6.01	NOS2-CD74 complex	cellular component	GO:0035693	1	1	19108	47	CD74
2.462e-03	-6.01	Semaphorin interactions	REACTOME pathways	R-HSA-373755	68	3	10285	41	PLXND1,RAC2,PLXNC1
2.466e-03	-6.01	defense response to symbiont	biological process	GO:0140546	894	8	18204	49	CD74,MLKL,CSF1R,TNFAIP8L2,ITGAX,UNC93B1,HCK,MARCO
2.466e-03	-6.01	regulation of anatomical structure morphogenesis	biological process	GO:0022603	894	8	18204	49	ITGB2,ITGAX,PLXNC1,HCK,GAB1,CYFIP1,PLXND1,CSF1R
2.467e-03	-6.00	hematopoietic progenitor cell differentiation	biological process	GO:0002244	100	3	18204	49	SH2B3,PLEK,RBM47
2.540e-03	-5.98	Other semaphorin interactions	REACTOME pathways	R-HSA-416700	19	2	10285	41	PLXND1,PLXNC1
2.559e-03	-5.97	SGCA (sarcoglycan alpha)	protein interactions	6442	106	3	19454	50	CMTM6,SMPD4,ITM2B
2.566e-03	-5.97	positive regulation of lamellipodium assembly	biological process	GO:0010592	28	2	18204	49	CYFIP1,RAC2
2.570e-03	-5.96	pparg.L (peroxisome proliferator activated receptor gamma L homeolog)	protein interactions	397769	1	1	19454	50	RXRA
2.570e-03	-5.96	ATP2A2 (ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2)	protein interactions	103239106	1	1	19454	50	VMP1
2.570e-03	-5.96	Parp1 (poly (ADP-ribose) polymerase 1)	protein interactions	25591	1	1	19454	50	RXRA
2.570e-03	-5.96	SCGB3A2 (secretoglobin family 3A member 2)	protein interactions	117156	1	1	19454	50	MARCO
2.581e-03	-5.96	Plexin_repeat	interpro domains	IPR002165	28	2	18521	50	PLXNC1,PLXND1
2.601e-03	-5.95	negative regulation of cell activation	biological process	GO:0050866	214	4	18204	49	TNFAIP8L2,INPP5D,CD74,SH2B3
2.603e-03	-5.95	NHLRC2 (NHL repeat containing 2)	protein interactions	374354	372	5	19454	50	PLEK,MYO1F,RASGRP2,RAC2,ITGAX
2.631e-03	-5.94	integrin complex	cellular component	GO:0008305	31	2	19108	47	ITGAX,ITGB2
2.682e-03	-5.92	PSI	pfam domains	PF01437	28	2	17795	49	PLXND1,PLXNC1
2.688e-03	-5.92	PIK3R2 (phosphoinositide-3-kinase regulatory subunit 2)	protein interactions	5296	226	4	19454	50	HCK,GAB1,RAC2,CSF1R
2.690e-03	-5.92	CLEC4G (C-type lectin domain family 4 member G)	protein interactions	339390	30	2	19454	50	CPN1,MAP3K11
2.690e-03	-5.92	PECAM1 (platelet and endothelial cell adhesion molecule 1)	protein interactions	5175	30	2	19454	50	INPP5D,HCK
2.690e-03	-5.92	cell chemotaxis	biological process	GO:0060326	216	4	18204	49	CSF3R,GAB1,ITGB2,PREX1
2.690e-03	-5.92	regulation of myeloid cell differentiation	biological process	GO:0045637	216	4	18204	49	INPP5D,ZFP36L1,CSF3R,CD74
2.692e-03	-5.92	ganglioside GM1 transport to membrane	biological process	GO:1905572	1	1	18204	49	PSAP
2.692e-03	-5.92	positive regulation of endothelial tube morphogenesis	biological process	GO:1905956	1	1	18204	49	ITGAX
2.692e-03	-5.92	positive regulation of inositol-polyphosphate 5-phosphatase activity	biological process	GO:0010925	1	1	18204	49	PLEK
2.692e-03	-5.92	pyrimidine deoxyribonucleoside catabolic process	biological process	GO:0046127	1	1	18204	49	DPYD
2.692e-03	-5.92	positive regulation of beta-galactosidase activity	biological process	GO:1903771	1	1	18204	49	PSAP
2.692e-03	-5.92	cellular response to pyrimidine ribonucleotide	biological process	GO:1905835	1	1	18204	49	P2RY6
2.692e-03	-5.92	regulation of cell diameter	biological process	GO:0060305	1	1	18204	49	PLEK
2.692e-03	-5.92	response to pyrimidine ribonucleotide	biological process	GO:1905834	1	1	18204	49	P2RY6
2.692e-03	-5.92	thymidine catabolic process	biological process	GO:0006214	1	1	18204	49	DPYD
2.692e-03	-5.92	protein secretion by platelet	biological process	GO:0070560	1	1	18204	49	PLEK
2.692e-03	-5.92	regulation of inositol-polyphosphate 5-phosphatase activity	biological process	GO:0010924	1	1	18204	49	PLEK
2.692e-03	-5.92	phospholipase C-inhibiting G protein-coupled receptor signaling pathway	biological process	GO:0030845	1	1	18204	49	PLEK
2.692e-03	-5.92	macrophage migration inhibitory factor signaling pathway	biological process	GO:0035691	1	1	18204	49	CD74
2.698e-03	-5.92	SLC39A14 (solute carrier family 39 member 14)	protein interactions	23516	108	3	19454	50	UNC93B1,RAC2,P2RY6
2.700e-03	-5.91	PLEK_DEP	interpro domains	IPR037371	1	1	18521	50	PLEK
2.700e-03	-5.91	UNC93B1	interpro domains	IPR043268	1	1	18521	50	UNC93B1
2.700e-03	-5.91	DPD_II	interpro domains	IPR028261	1	1	18521	50	DPYD
2.700e-03	-5.91	SNX17_FERM-like_dom	interpro domains	IPR037836	1	1	18521	50	SNX17
2.700e-03	-5.91	M14_CPN	interpro domains	IPR033814	1	1	18521	50	CPN1
2.700e-03	-5.91	FYB_hSH3	interpro domains	IPR035540	1	1	18521	50	FYB1
2.700e-03	-5.91	ABR_PH	interpro domains	IPR037865	1	1	18521	50	ABR
2.700e-03	-5.91	RBM47_RRM1	interpro domains	IPR047044	1	1	18521	50	RBM47
2.700e-03	-5.91	MHCII_invariant_trimer_sf	interpro domains	IPR036613	1	1	18521	50	CD74
2.700e-03	-5.91	RBM47_RRM2	interpro domains	IPR034440	1	1	18521	50	RBM47
2.700e-03	-5.91	DHR2_DOCK2	interpro domains	IPR026799	1	1	18521	50	DOCK2
2.700e-03	-5.91	HCK_SH2	interpro domains	IPR035851	1	1	18521	50	HCK
2.700e-03	-5.91	CSF-1_receptor	interpro domains	IPR030658	1	1	18521	50	CSF1R
2.700e-03	-5.91	CD74_antigen	interpro domains	IPR043530	1	1	18521	50	CD74
2.700e-03	-5.91	DAPP1_SH2	interpro domains	IPR035843	1	1	18521	50	DAPP1
2.700e-03	-5.91	Integrin_b-2_sf	interpro domains	IPR015439	1	1	18521	50	ITGB2
2.700e-03	-5.91	Plexin-C1_Sema	interpro domains	IPR041853	1	1	18521	50	PLXNC1
2.700e-03	-5.91	SNX17_FERM_N	interpro domains	IPR028666	1	1	18521	50	SNX17
2.700e-03	-5.91	RMC1_C	interpro domains	IPR009755	1	1	18521	50	RMC1
2.700e-03	-5.91	RMC1	interpro domains	IPR040371	1	1	18521	50	RMC1
2.700e-03	-5.91	Plexin-D1_Sema	interpro domains	IPR042719	1	1	18521	50	PLXND1
2.700e-03	-5.91	MHC_II-assoc_invar/CLIP_MHC-bd	interpro domains	IPR015386	1	1	18521	50	CD74
2.700e-03	-5.91	MHC_II-assoc_invar_chain	interpro domains	IPR022339	1	1	18521	50	CD74
2.700e-03	-5.91	SH2B3_SH2	interpro domains	IPR035059	1	1	18521	50	SH2B3
2.700e-03	-5.91	P2Y6_rcpt	interpro domains	IPR001973	1	1	18521	50	P2RY6
2.700e-03	-5.91	Sphingomy_SMPD4	interpro domains	IPR024129	1	1	18521	50	SMPD4
2.700e-03	-5.91	RBM47_RRM3	interpro domains	IPR034445	1	1	18521	50	RBM47
2.700e-03	-5.91	RMC1_N	interpro domains	IPR049040	1	1	18521	50	RMC1
2.700e-03	-5.91	LRMDA	interpro domains	IPR043313	1	1	18521	50	LRMDA
2.700e-03	-5.91	MHC_II-assoc_invariant_trimer	interpro domains	IPR011988	1	1	18521	50	CD74
2.708e-03	-5.91	MHC class II protein binding, via antigen binding groove	molecular function	GO:0042658	1	1	18094	49	CD74
2.708e-03	-5.91	granulocyte colony-stimulating factor binding	molecular function	GO:0051916	1	1	18094	49	CSF3R
2.708e-03	-5.91	sphingomyelin phosphodiesterase D activity	molecular function	GO:0050290	1	1	18094	49	SMPD4
2.708e-03	-5.91	uracil binding	molecular function	GO:0002058	1	1	18094	49	DPYD
2.708e-03	-5.91	ganglioside GP1c binding	molecular function	GO:1905577	1	1	18094	49	PSAP
2.708e-03	-5.91	ganglioside GM3 binding	molecular function	GO:1905575	1	1	18094	49	PSAP
2.708e-03	-5.91	pyrimidine nucleobase binding	molecular function	GO:0002061	1	1	18094	49	DPYD
2.708e-03	-5.91	ITPase activity	molecular function	GO:0103023	1	1	18094	49	ENTPD1
2.708e-03	-5.91	dihydropyrimidine dehydrogenase (NADP+) activity	molecular function	GO:0017113	1	1	18094	49	DPYD
2.708e-03	-5.91	ganglioside GM2 binding	molecular function	GO:1905574	1	1	18094	49	PSAP
2.731e-03	-5.90	PRKCD (protein kinase C delta)	protein interactions	5580	227	4	19454	50	INPP5D,CSF3R,ITGB2,RMC1
2.732e-03	-5.90	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-diffuse_large_B_cell_lymphoma	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-diffuse_large_B_cell_lymphoma	3608	18	16828	44	ZFP36L1,MARCO,ITM2B,SMPD4,GAB1,CD74,SLCO2B1,THRB,NCAM2,DOCK2,VMP1,ELMO1,PLXNC1,DPYD,HCK,PSAP,PLXND1,ANKRD44
2.754e-03	-5.89	MHC2-interact	pfam domains	PF09307	1	1	17795	49	CD74
2.754e-03	-5.89	Fer4_20	pfam domains	PF14691	1	1	17795	49	DPYD
2.754e-03	-5.89	Fer4_21	pfam domains	PF14697	1	1	17795	49	DPYD
2.754e-03	-5.89	RMC1_N	pfam domains	PF21029	1	1	17795	49	RMC1
2.754e-03	-5.89	mit_SMPDase	pfam domains	PF14724	1	1	17795	49	SMPD4
2.754e-03	-5.89	MHCassoc_trimer	pfam domains	PF08831	1	1	17795	49	CD74
2.754e-03	-5.89	RMC1_C	pfam domains	PF07035	1	1	17795	49	RMC1
2.770e-03	-5.89	plasma membrane raft	cellular component	GO:0044853	114	3	19108	47	ITGB2,ENTPD1,HCK
2.784e-03	-5.88	phosphatidylinositol-3,4-bisphosphate binding	molecular function	GO:0043325	29	2	18094	49	PLEK,DAPP1
2.789e-03	-5.88	NOTCH2NLA (notch 2 N-terminal like A)	protein interactions	388677	378	5	19454	50	DOCK2,INPP5D,P2RY6,ITGB2,HCK
2.804e-03	-5.88	ntegrin, alpha v. Chain A, domain 3	gene3d domains	2.60.40.1510	26	2	14470	44	ITGAX,ITGB2
2.830e-03	-5.87	Neutrophil degranulation	REACTOME pathways	R-HSA-6798695	487	7	10285	41	DOCK2,CMTM6,ITGAX,PSAP,CD68,CYFIP1,ITGB2
2.834e-03	-5.87	positive regulation of myeloid cell differentiation	biological process	GO:0045639	105	3	18204	49	INPP5D,CD74,ZFP36L1
2.836e-03	-5.87	lymphoid_neoplasm	COSMIC cancer mutations	lymphoid_neoplasm	12233	40	16828	44	PSAP,CSF1R,RASGRP2,PLXNC1,CMTM6,ABR,RXRA,TNFAIP8L2,PREX1,ITGB2,SPOCK3,THRB,CSF3R,DOCK2,VMP1,NCAM2,PLEK,RBM47,MFNG,GAB1,RAC2,SMPD4,PLXND1,SNX17,MYO1F,HCK,DPYD,ENTPD1,ANKRD44,ELMO1,ITGAX,SH2B3,MLKL,MAP3K11,CPN1,SLCO2B1,ITM2B,MARCO,ZFP36L1,CD74
2.908e-03	-5.84	NBPF19 (NBPF member 19)	protein interactions	101060226	231	4	19454	50	ITGB2,HCK,DOCK2,P2RY6
2.911e-03	-5.84	mixed_intestinal_and_diffuse_adenocarcinoma-unclassifiable	COSMIC cancer mutations	mixed_intestinal_and_diffuse_adenocarcinoma-unclassifiable	951	8	16828	44	SH2B3,PREX1,ELMO1,ANKRD44,NCAM2,DOCK2,DPYD,HCK
2.911e-03	-5.84	stomach-carcinoma-mixed_intestinal_and_diffuse_adenocarcinoma-unclassifiable	COSMIC cancer mutations	stomach-carcinoma-mixed_intestinal_and_diffuse_adenocarcinoma-unclassifiable	951	8	16828	44	SH2B3,PREX1,ELMO1,ANKRD44,NCAM2,DOCK2,HCK,DPYD
2.914e-03	-5.84	haematopoietic_and_lymphoid_tissue-haematopoietic_neoplasm-myelodysplastic_syndrome	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue-haematopoietic_neoplasm-myelodysplastic_syndrome	1174	9	16828	44	DOCK2,CSF3R,PLXNC1,HCK,CSF1R,MAP3K11,MLKL,SH2B3,GAB1
2.914e-03	-5.84	myelodysplastic_syndrome	COSMIC cancer mutations	myelodysplastic_syndrome	1174	9	16828	44	DOCK2,PLXNC1,CSF3R,HCK,CSF1R,MLKL,MAP3K11,SH2B3,GAB1
2.954e-03	-5.82	HLA-B (major histocompatibility complex, class I, B)	protein interactions	3106	232	4	19454	50	RAC2,SMPD4,ADAM33,ITM2B
2.961e-03	-5.82	IPT_dom	interpro domains	IPR002909	30	2	18521	50	PLXNC1,PLXND1
3.041e-03	-5.80	-	gene3d domains	6.20.50.10	1	1	14470	44	ITGB2
3.041e-03	-5.80	MHC class II-associated invariant chain, trimerisation domain	gene3d domains	1.10.870.10	1	1	14470	44	CD74
3.057e-03	-5.79	RASA3 (RAS p21 protein activator 3)	protein interactions	22821	32	2	19454	50	HCK,RAC2
3.057e-03	-5.79	ALPL (alkaline phosphatase, biomineralization associated)	protein interactions	249	32	2	19454	50	VMP1,RAC2
3.117e-03	-5.77	myelodysplastic-myeloproliferative_neoplasm-unclassifiable	COSMIC cancer mutations	myelodysplastic-myeloproliferative_neoplasm-unclassifiable	112	3	16828	44	SH2B3,CSF3R,CSF1R
3.117e-03	-5.77	haematopoietic_and_lymphoid_tissue-haematopoietic_neoplasm-myelodysplastic-myeloproliferative_neoplasm-unclassifiable	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue-haematopoietic_neoplasm-myelodysplastic-myeloproliferative_neoplasm-unclassifiable	112	3	16828	44	SH2B3,CSF1R,CSF3R
3.140e-03	-5.76	antigen processing and presentation of exogenous peptide antigen via MHC class II	biological process	GO:0019886	31	2	18204	49	UNC93B1,CD74
3.140e-03	-5.76	positive regulation of calcium ion transmembrane transporter activity	biological process	GO:1901021	31	2	18204	49	P2RY6,VMP1
3.141e-03	-5.76	CTSL (cathepsin L)	protein interactions	1514	236	4	19454	50	CD74,PSAP,ITM2B,RXRA
3.144e-03	-5.76	ACVR1 (activin A receptor type 1)	protein interactions	90	114	3	19454	50	THRB,RXRA,PLEK
3.159e-03	-5.76	Semap_dom_sf	interpro domains	IPR036352	31	2	18521	50	PLXNC1,PLXND1
3.159e-03	-5.76	Semap_dom	interpro domains	IPR001627	31	2	18521	50	PLXND1,PLXNC1
3.249e-03	-5.73	ELMO3 (engulfment and cell motility 3)	protein interactions	79767	33	2	19454	50	ELMO1,RAC2
3.249e-03	-5.73	HS6ST1 (heparan sulfate 6-O-sulfotransferase 1)	protein interactions	9394	33	2	19454	50	MFNG,ITM2B
3.302e-03	-5.71	THEM6 (thioesterase superfamily member 6)	protein interactions	51337	116	3	19454	50	RAC2,P2RY6,UNC93B1
3.308e-03	-5.71	cellular response to cytokine stimulus	biological process	GO:0071345	734	7	18204	49	CD74,SH2B3,ZFP36L1,CSF3R,CSF1R,HCK,SMPD4
3.335e-03	-5.70	SLC1A5 (solute carrier family 1 member 5)	protein interactions	6510	240	4	19454	50	P2RY6,RAC2,UNC93B1,RMC1
3.345e-03	-5.70	actin cytoskeleton organization	biological process	GO:0030036	547	6	18204	49	PLEK,MYO1F,DOCK2,PREX1,RAC2,ELMO1
3.406e-03	-5.68	localization within membrane	biological process	GO:0051668	549	6	18204	49	CMTM6,DOCK2,ITGB2,FYB1,SNX17,PSAP
3.436e-03	-5.67	STT3B (STT3 oligosaccharyltransferase complex catalytic subunit B)	protein interactions	201595	242	4	19454	50	UNC93B1,MLKL,RAC2,P2RY6
3.446e-03	-5.67	ELMO1 (engulfment and cell motility 1)	protein interactions	9844	34	2	19454	50	HCK,DOCK2
3.446e-03	-5.67	SEMA4F (ssemaphorin 4F)	protein interactions	10505	34	2	19454	50	ADAM33,ITM2B
3.553e-03	-5.64	regulation of neutrophil chemotaxis	biological process	GO:0090022	33	2	18204	49	CD74,RAC2
3.553e-03	-5.64	antigen processing and presentation of peptide antigen via MHC class II	biological process	GO:0002495	33	2	18204	49	UNC93B1,CD74
3.553e-03	-5.64	positive regulation of neutrophil migration	biological process	GO:1902624	33	2	18204	49	RAC2,CD74
3.622e-03	-5.62	B cell receptor signaling pathway	KEGG pathways	hsa04662	70	3	7161	32	DAPP1,RAC2,INPP5D
3.622e-03	-5.62	B cell receptor signaling pathway	KEGG pathways	ko04662	70	3	7161	32	INPP5D,DAPP1,RAC2
3.623e-03	-5.62	regulation of actin filament-based process	biological process	GO:0032970	384	5	18204	49	PLEK,CYFIP1,PREX1,HCK,CSF1R
3.623e-03	-5.62	cytokine-mediated signaling pathway	biological process	GO:0019221	384	5	18204	49	HCK,CSF1R,CSF3R,SH2B3,CD74
3.649e-03	-5.61	Mbp (myelin basic protein)	protein interactions	17196	35	2	19454	50	HCK,FYB1
3.649e-03	-5.61	JAG1 (jagged canonical Notch ligand 1)	protein interactions	182	35	2	19454	50	RAC2,MFNG
3.724e-03	-5.59	ligand-binding face of the semaphorins, domain 2	gene3d domains	3.30.1680.10	30	2	14470	44	ITGB2,PLXNC1
3.749e-03	-5.59	SYK (spleen associated tyrosine kinase)	protein interactions	6850	248	4	19454	50	INPP5D,GAB1,ITGB2,CSF3R
3.769e-03	-5.58	positive T cell selection	biological process	GO:0043368	34	2	18204	49	CD74,DOCK2
3.769e-03	-5.58	antigen processing and presentation of peptide or polysaccharide antigen via MHC class II	biological process	GO:0002504	34	2	18204	49	UNC93B1,CD74
3.769e-03	-5.58	regulation of B cell differentiation	biological process	GO:0045577	34	2	18204	49	ZFP36L1,INPP5D
3.887e-03	-5.55	positive regulation of response to external stimulus	biological process	GO:0032103	564	6	18204	49	CSF1R,RBM47,UNC93B1,HCK,CD74,RAC2
3.893e-03	-5.55	EIF2B3 (eukaryotic translation initiation factor 2B subunit gamma)	protein interactions	8891	123	3	19454	50	UNC93B1,CD74,P2RY6
3.899e-03	-5.55	cell leading edge	cellular component	GO:0031252	428	5	19108	47	PLEK,RASGRP2,RAC2,CYFIP1,PLXND1
3.949e-03	-5.53	IPT	smart domains	SM00429	27	2	9717	34	PLXNC1,PLXND1
4.050e-03	-5.51	small_intestine	COSMIC cancer mutations	small_intestine	250	4	16828	44	VMP1,PREX1,CSF1R,PLXND1
4.146e-03	-5.49	endosome	cellular component	GO:0005768	1067	8	19108	47	RMC1,SNX17,PSAP,CD74,ITM2B,UNC93B1,CD68,CMTM6
4.209e-03	-5.47	P2Y6PRNOCPTR	prints domains	PR01068	1	1	5227	22	P2RY6
4.209e-03	-5.47	CD74ANTIGEN	prints domains	PR01990	1	1	5227	22	CD74
4.218e-03	-5.47	positive regulation of lamellipodium organization	biological process	GO:1902745	36	2	18204	49	RAC2,CYFIP1
4.220e-03	-5.47	leukocyte migration	biological process	GO:0050900	245	4	18204	49	HCK,ITGB2,PREX1,CSF3R
4.296e-03	-5.45	Signaling by Interleukins	REACTOME pathways	R-HSA-449147	525	7	10285	41	CSF3R,MAP3K11,CSF1R,INPP5D,HCK,ITGB2,ITGAX
4.316e-03	-5.45	env (Envelope surface glycoprotein gp160, precursor)	protein interactions	155971	1501	10	19454	50	INPP5D,ITM2B,CD74,SMPD4,RXRA,ITGB2,ITGAX,MAP3K11,ABR,HCK
4.322e-03	-5.44	regulation of leukocyte chemotaxis	biological process	GO:0002688	122	3	18204	49	CSF1R,RAC2,CD74
4.352e-03	-5.44	BTK (Bruton tyrosine kinase)	protein interactions	695	128	3	19454	50	HCK,DAPP1,GAB1
4.352e-03	-5.44	RAB18 (RAB18, member RAS oncogene family)	protein interactions	22931	128	3	19454	50	P2RY6,VMP1,UNC93B1
4.451e-03	-5.41	cellular response to low-density lipoprotein particle stimulus	biological process	GO:0071404	37	2	18204	49	CD68,ITGB2
4.451e-03	-5.41	response to lipoprotein particle	biological process	GO:0055094	37	2	18204	49	CD68,ITGB2
4.545e-03	-5.39	HM13 (histocompatibility minor 13)	protein interactions	81502	130	3	19454	50	RAC2,UNC93B1,CMTM6
4.545e-03	-5.39	YIPF5 (Yip1 domain family member 5)	protein interactions	81555	130	3	19454	50	UNC93B1,P2RY6,RAC2
4.691e-03	-5.36	heterotypic cell-cell adhesion	biological process	GO:0034113	38	2	18204	49	ITGB2,ITGAX
4.742e-03	-5.35	OSBPL8 (oxysterol binding protein like 8)	protein interactions	114882	265	4	19454	50	CD74,P2RY6,RAC2,UNC93B1
4.747e-03	-5.35	response to hormone	biological process	GO:0009725	784	7	18204	49	ZFP36L1,CYFIP1,GAB1,P2RY6,THRB,CPN1,RXRA
4.750e-03	-5.35	RAC3 (Rac family small GTPase 3)	protein interactions	5881	615	6	19454	50	MAP3K11,SMPD4,GAB1,RAC2,CYFIP1,ITM2B
4.782e-03	-5.34	SH3DOMAIN	prints domains	PR00452	83	3	5227	22	MYO1F,HCK,MAP3K11
4.785e-03	-5.34	Fcgamma receptor (FCGR) dependent phagocytosis	REACTOME pathways	R-HSA-2029480	86	3	10285	41	ELMO1,CYFIP1,HCK
4.835e-03	-5.33	regulation of myeloid leukocyte differentiation	biological process	GO:0002761	127	3	18204	49	INPP5D,CD74,ZFP36L1
4.843e-03	-5.33	PLAUR (plasminogen activator, urokinase receptor)	protein interactions	5329	133	3	19454	50	PSAP,ITGB2,HCK
4.913e-03	-5.32	integrin alphaL-beta2 complex	cellular component	GO:0034687	2	1	19108	47	ITGB2
4.913e-03	-5.32	CSF1-CSF1R complex	cellular component	GO:1990682	2	1	19108	47	CSF1R
4.913e-03	-5.32	macrophage migration inhibitory factor receptor complex	cellular component	GO:0035692	2	1	19108	47	CD74
4.913e-03	-5.32	integrin alphaM-beta2 complex	cellular component	GO:0034688	2	1	19108	47	ITGB2
4.913e-03	-5.32	peripheral region of growth cone	cellular component	GO:0090725	2	1	19108	47	CYFIP1
4.942e-03	-5.31	regulation of B cell activation	biological process	GO:0050864	128	3	18204	49	ZFP36L1,CD74,INPP5D
4.980e-03	-5.30	RXRG (retinoid X receptor gamma)	protein interactions	6258	41	2	19454	50	RXRA,THRB
4.980e-03	-5.30	PSMC3IP (PSMC3 interacting protein)	protein interactions	29893	41	2	19454	50	THRB,RXRA
4.980e-03	-5.30	ATP8 (ATP synthase F0 subunit 8)	protein interactions	4509	41	2	19454	50	P2RY6,UNC93B1
4.999e-03	-5.30	PGRMC2 (progesterone receptor membrane component 2)	protein interactions	10424	269	4	19454	50	RAC2,VMP1,P2RY6,CD74
5.062e-03	-5.29	defense response to other organism	biological process	GO:0098542	1006	8	18204	49	CSF1R,MLKL,CD74,UNC93B1,HCK,MARCO,TNFAIP8L2,ITGAX
5.103e-03	-5.28	G alpha (12/13) signalling events	REACTOME pathways	R-HSA-416482	88	3	10285	41	ABR,PREX1,RAC2
5.186e-03	-5.26	Sema	smart domains	SM00630	31	2	9717	34	PLXNC1,PLXND1
5.187e-03	-5.26	cellular response to lipoprotein particle stimulus	biological process	GO:0071402	40	2	18204	49	ITGB2,CD68
5.220e-03	-5.26	NR2F6 (nuclear receptor subfamily 2 group F member 6)	protein interactions	2063	42	2	19454	50	THRB,RXRA
5.259e-03	-5.25	C3 (complement C3)	protein interactions	718	137	3	19454	50	ITGB2,ITGAX,CPN1
5.300e-03	-5.24	SEMA	prosite domains	PS51004	31	2	12186	43	PLXNC1,PLXND1
5.366e-03	-5.23	ATP5MG (ATP synthase membrane subunit g)	protein interactions	10632	138	3	19454	50	UNC93B1,RBM47,P2RY6
5.376e-03	-5.23	regulation of prostaglandin-E synthase activity	biological process	GO:2000361	2	1	18204	49	ITGB2
5.376e-03	-5.23	negative regulation of dopamine metabolic process	biological process	GO:0045963	2	1	18204	49	ITGB2
5.376e-03	-5.23	negative regulation of synaptic vesicle recycling	biological process	GO:1903422	2	1	18204	49	CYFIP1
5.376e-03	-5.23	negative regulation of neutrophil differentiation	biological process	GO:0045659	2	1	18204	49	INPP5D
5.376e-03	-5.23	retinal cone cell apoptotic process	biological process	GO:0097474	2	1	18204	49	THRB
5.376e-03	-5.23	beta-alanine biosynthetic process	biological process	GO:0019483	2	1	18204	49	DPYD
5.376e-03	-5.23	female courtship behavior	biological process	GO:0008050	2	1	18204	49	THRB
5.376e-03	-5.23	uracil catabolic process	biological process	GO:0006212	2	1	18204	49	DPYD
5.376e-03	-5.23	negative regulation of catecholamine metabolic process	biological process	GO:0045914	2	1	18204	49	ITGB2
5.376e-03	-5.23	regulation of Kit signaling pathway	biological process	GO:1900234	2	1	18204	49	SH2B3
5.376e-03	-5.23	positive regulation of macrophage migration inhibitory factor signaling pathway	biological process	GO:2000448	2	1	18204	49	CD74
5.376e-03	-5.23	negative regulation of inositol phosphate biosynthetic process	biological process	GO:0010920	2	1	18204	49	PLEK
5.376e-03	-5.23	negative regulation of Kit signaling pathway	biological process	GO:1900235	2	1	18204	49	SH2B3
5.376e-03	-5.23	execution phase of necroptosis	biological process	GO:0097528	2	1	18204	49	MLKL
5.376e-03	-5.23	positive regulation of prostaglandin-E synthase activity	biological process	GO:2000363	2	1	18204	49	ITGB2
5.376e-03	-5.23	synaptic target recognition	biological process	GO:0008039	2	1	18204	49	PLXND1
5.392e-03	-5.22	Helical_ferredxn	interpro domains	IPR009051	2	1	18521	50	DPYD
5.392e-03	-5.22	SNX17-31_FERM_F1	interpro domains	IPR048763	2	1	18521	50	SNX17
5.392e-03	-5.22	Pleckstrin	interpro domains	IPR037370	2	1	18521	50	PLEK
5.392e-03	-5.22	Abr/Bcr	interpro domains	IPR037769	2	1	18521	50	ABR
5.392e-03	-5.22	Bcr-Abl_oncoprot_oligo	interpro domains	IPR015123	2	1	18521	50	ABR
5.392e-03	-5.22	Nuc_recep-AF1	interpro domains	IPR021780	2	1	18521	50	RXRA
5.392e-03	-5.22	Ie/If_SH3	interpro domains	IPR035507	2	1	18521	50	MYO1F
5.392e-03	-5.22	Tis11B_N	interpro domains	IPR007635	2	1	18521	50	ZFP36L1
5.392e-03	-5.22	SNX17-31_FERM_F2	interpro domains	IPR048767	2	1	18521	50	SNX17
5.392e-03	-5.22	Neural_cell_adh	interpro domains	IPR009138	2	1	18521	50	NCAM2
5.392e-03	-5.22	Bcr-Abl_oncoprot_oligo_sf	interpro domains	IPR036481	2	1	18521	50	ABR
5.392e-03	-5.22	SNX17/31_FERM	interpro domains	IPR040842	2	1	18521	50	SNX17
5.392e-03	-5.22	Cytoplasmic_FMR1-int	interpro domains	IPR008081	2	1	18521	50	CYFIP1
5.392e-03	-5.22	Saposin_chordata	interpro domains	IPR021165	2	1	18521	50	PSAP
5.392e-03	-5.22	Dihydroorotate_DH_cat	interpro domains	IPR005720	2	1	18521	50	DPYD
5.409e-03	-5.22	macrophage colony-stimulating factor receptor activity	molecular function	GO:0005011	2	1	18094	49	CSF1R
5.409e-03	-5.22	macrophage migration inhibitory factor binding	molecular function	GO:0035718	2	1	18094	49	CD74
5.409e-03	-5.22	G protein-coupled UDP receptor activity	molecular function	GO:0045029	2	1	18094	49	P2RY6
5.443e-03	-5.21	cell adhesion mediated by integrin	biological process	GO:0033627	41	2	18204	49	ITGAX,ITGB2
5.443e-03	-5.21	antigen processing and presentation of exogenous peptide antigen	biological process	GO:0002478	41	2	18204	49	UNC93B1,CD74
5.443e-03	-5.21	regulation of lamellipodium assembly	biological process	GO:0010591	41	2	18204	49	RAC2,CYFIP1
5.468e-03	-5.21	regulation of multicellular organismal development	biological process	GO:2000026	1484	10	18204	49	RXRA,ITGAX,PLXNC1,CD74,GAB1,CYFIP1,CSF3R,ZFP36L1,PLXND1,INPP5D
5.471e-03	-5.21	HMOX2 (heme oxygenase 2)	protein interactions	3163	276	4	19454	50	CD74,P2RY6,RAC2,UNC93B1
5.500e-03	-5.20	DHO_dh	pfam domains	PF01180	2	1	17795	49	DPYD
5.500e-03	-5.20	SNX17-31_F2_FERM	pfam domains	PF21271	2	1	17795	49	SNX17
5.500e-03	-5.20	Bcr-Abl_Oligo	pfam domains	PF09036	2	1	17795	49	ABR
5.500e-03	-5.20	Nuc_recep-AF1	pfam domains	PF11825	2	1	17795	49	RXRA
5.500e-03	-5.20	FragX_IP	pfam domains	PF05994	2	1	17795	49	CYFIP1
5.500e-03	-5.20	SNX17_FERM_C	pfam domains	PF18116	2	1	17795	49	SNX17
5.500e-03	-5.20	Tis11B_N	pfam domains	PF04553	2	1	17795	49	ZFP36L1
5.500e-03	-5.20	SNX17-27-31_F1_FERM	pfam domains	PF21273	2	1	17795	49	SNX17
5.552e-03	-5.19	membrane raft	cellular component	GO:0045121	290	4	19108	47	ITGB2,INPP5D,ENTPD1,HCK
5.553e-03	-5.19	stomach-carcinoma	COSMIC cancer mutations	stomach-carcinoma	439	5	16828	44	CSF1R,MAP3K11,MLKL,CSF3R,HCK
5.612e-03	-5.18	regulation of actin filament polymerization	biological process	GO:0030833	134	3	18204	49	CYFIP1,PREX1,HCK
5.687e-03	-5.17	membrane microdomain	cellular component	GO:0098857	292	4	19108	47	HCK,ENTPD1,INPP5D,ITGB2
5.696e-03	-5.17	NCAPD3 (non-SMC condensin II complex subunit D3)	protein interactions	23310	141	3	19454	50	UNC93B1,CD74,P2RY6
5.721e-03	-5.16	upper_aerodigestive_tract-mouth-carcinoma-squamous_cell_carcinoma	COSMIC cancer mutations	upper_aerodigestive_tract-mouth-carcinoma-squamous_cell_carcinoma	6953	27	16828	44	RBM47,GAB1,MFNG,SMPD4,RAC2,CSF3R,DOCK2,NCAM2,RXRA,ABR,PREX1,ITGB2,SPOCK3,CSF1R,PSAP,PLXNC1,RASGRP2,ZFP36L1,SLCO2B1,ELMO1,ITGAX,MYO1F,PLXND1,DPYD,HCK,ENTPD1,ANKRD44
5.760e-03	-5.16	regulation of developmental process	biological process	GO:0050793	2540	14	18204	49	PREX1,ITGB2,HCK,GAB1,ZFP36L1,CSF3R,CD74,RXRA,ITGAX,PLXNC1,CYFIP1,PLXND1,INPP5D,CSF1R
5.788e-03	-5.15	regulation of leukocyte proliferation	biological process	GO:0070663	268	4	18204	49	CD74,RAC2,INPP5D,CSF1R
5.864e-03	-5.14	regulation of actin filament organization	biological process	GO:0110053	269	4	18204	49	HCK,PLEK,CYFIP1,PREX1
5.899e-03	-5.13	regulation of signal transduction	biological process	GO:0009966	3114	16	18204	49	MAP3K11,SH2B3,PREX1,MFNG,THRB,ABR,PLEK,P2RY6,CD74,RBM47,MARCO,RXRA,INPP5D,CSF1R,CYFIP1,DOCK2
5.922e-03	-5.13	ATP13A3 (ATPase 13A3)	protein interactions	79572	143	3	19454	50	RAC2,P2RY6,UNC93B1
5.952e-03	-5.12	actin filament-based process	biological process	GO:0030029	616	6	18204	49	RAC2,ELMO1,PREX1,DOCK2,MYO1F,PLEK
5.967e-03	-5.12	myeloid leukocyte migration	biological process	GO:0097529	137	3	18204	49	CSF3R,ITGB2,PREX1
5.967e-03	-5.12	cell recognition	biological process	GO:0008037	137	3	18204	49	PLXND1,DOCK2,NCAM2
5.973e-03	-5.12	EPOR (erythropoietin receptor)	protein interactions	2057	45	2	19454	50	INPP5D,GAB1
5.973e-03	-5.12	SKAP2 (src kinase associated phosphoprotein 2)	protein interactions	8935	45	2	19454	50	HCK,FYB1
5.974e-03	-5.12	erythrocyte development	biological process	GO:0048821	43	2	18204	49	SH2B3,RAC2
5.974e-03	-5.12	regulation of bone resorption	biological process	GO:0045124	43	2	18204	49	INPP5D,CSF1R
5.974e-03	-5.12	semaphorin-plexin signaling pathway	biological process	GO:0071526	43	2	18204	49	PLXND1,PLXNC1
5.982e-03	-5.12	secretory granule	cellular component	GO:0030141	897	7	19108	47	CMTM6,CD68,ITGB2,DOCK2,CYFIP1,ITGAX,PSAP
6.037e-03	-5.11	COPG2 (COPI coat complex subunit gamma 2)	protein interactions	26958	144	3	19454	50	CD74,P2RY6,UNC93B1
6.073e-03	-5.10	Alpha-helical ferredoxin	gene3d domains	1.10.1060.10	2	1	14470	44	DPYD
6.073e-03	-5.10	Bcr-Abl oncoprotein oligomerisation domain	gene3d domains	4.10.280.30	2	1	14470	44	ABR
6.088e-03	-5.10	regulation of axonogenesis	biological process	GO:0050770	138	3	18204	49	CYFIP1,PLXND1,PLXNC1
6.108e-03	-5.10	LCK (LCK proto-oncogene, Src family tyrosine kinase)	protein interactions	3932	455	5	19454	50	CSF3R,HCK,DAPP1,SH2B3,GAB1
6.234e-03	-5.08	TM4SF18 (transmembrane 4 L six family member 18)	protein interactions	116441	46	2	19454	50	ITGB2,UNC93B1
6.272e-03	-5.07	SPTLC1 (serine palmitoyltransferase long chain base subunit 1)	protein interactions	10558	146	3	19454	50	P2RY6,VMP1,UNC93B1
6.458e-03	-5.04	Focal Adhesion	WikiPathways	WP306	195	4	5310	21	ITGAX,ITGB2,HCK,RAC2
6.461e-03	-5.04	positive regulation of chemotaxis	biological process	GO:0050921	141	3	18204	49	CD74,RAC2,CSF1R
6.478e-03	-5.04	organic cyclic compound catabolic process	biological process	GO:1901361	441	5	18204	49	ENTPD1,SLCO2B1,SNX17,DPYD,ZFP36L1
6.481e-03	-5.04	bone	COSMIC cancer mutations	bone	8157	30	16828	44	CSF1R,DAPP1,PSAP,PLXNC1,ABR,PREX1,CSF3R,DOCK2,VMP1,RBM47,MFNG,GAB1,MYO1F,SNX17,PLXND1,DPYD,HCK,ENTPD1,ANKRD44,P2RY6,ADAM33,ELMO1,ITGAX,CPN1,MLKL,MAP3K11,SLCO2B1,MARCO,ZFP36L1,CD68
6.512e-03	-5.03	ATP1B1 (ATPase Na+/K+ transporting subunit beta 1)	protein interactions	481	148	3	19454	50	UNC93B1,RAC2,P2RY6
6.527e-03	-5.03	regulation of neutrophil migration	biological process	GO:1902622	45	2	18204	49	CD74,RAC2
6.527e-03	-5.03	regulation of leukocyte degranulation	biological process	GO:0043300	45	2	18204	49	ITGB2,RAC2
6.577e-03	-5.02	actin filament organization	biological process	GO:0007015	278	4	18204	49	MYO1F,PREX1,RAC2,ELMO1
6.620e-03	-5.02	response to cytokine	biological process	GO:0034097	834	7	18204	49	HCK,SH2B3,SMPD4,CSF1R,ZFP36L1,CSF3R,CD74
6.654e-03	-5.01	azurophil granule	cellular component	GO:0042582	156	3	19108	47	CMTM6,CD68,PSAP
6.654e-03	-5.01	primary lysosome	cellular component	GO:0005766	156	3	19108	47	CMTM6,CD68,PSAP
6.660e-03	-5.01	KRTAP10-7 (keratin associated protein 10-7)	protein interactions	386675	292	4	19454	50	P2RY6,INPP5D,DOCK2,HCK
6.732e-03	-5.00	breast-carcinoma-basal_(triple-negative)_carcinoma	COSMIC cancer mutations	breast-carcinoma-basal_(triple-negative)_carcinoma	2981	15	16828	44	DPYD,RASGRP2,PLXND1,CSF1R,P2RY6,ELMO1,RXRA,SPOCK3,MAP3K11,NCAM2,VMP1,RBM47,RAC2,MFNG,GAB1
6.732e-03	-5.00	basal_(triple-negative)_carcinoma	COSMIC cancer mutations	basal_(triple-negative)_carcinoma	2981	15	16828	44	MFNG,GAB1,RAC2,RBM47,VMP1,NCAM2,MAP3K11,SPOCK3,RXRA,ELMO1,P2RY6,CSF1R,PLXND1,RASGRP2,DPYD
6.812e-03	-4.99	neuron recognition	biological process	GO:0008038	46	2	18204	49	PLXND1,NCAM2
6.812e-03	-4.99	mRNA transcription by RNA polymerase II	biological process	GO:0042789	46	2	18204	49	THRB,RXRA
6.812e-03	-4.99	regulation of myelination	biological process	GO:0031641	46	2	18204	49	CYFIP1,ITGAX
6.834e-03	-4.99	regulation of cell development	biological process	GO:0060284	839	7	18204	49	CYFIP1,ZFP36L1,CSF3R,CD74,INPP5D,PLXND1,PLXNC1
6.853e-03	-4.98	Znf_hrmn_rcpt	interpro domains	IPR001628	46	2	18521	50	THRB,RXRA
6.909e-03	-4.97	haematopoietic_and_lymphoid_tissue-haematopoietic_neoplasm-chronic_myelomonocytic_leukaemia	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue-haematopoietic_neoplasm-chronic_myelomonocytic_leukaemia	149	3	16828	44	CSF3R,CSF1R,SH2B3
6.909e-03	-4.97	chronic_myelomonocytic_leukaemia	COSMIC cancer mutations	chronic_myelomonocytic_leukaemia	149	3	16828	44	SH2B3,CSF3R,CSF1R
6.937e-03	-4.97	oesophagus-lower_third-carcinoma-adenocarcinoma	COSMIC cancer mutations	oesophagus-lower_third-carcinoma-adenocarcinoma	6302	25	16828	44	P2RY6,ANKRD44,DPYD,MYO1F,PLXND1,SH2B3,ITGAX,ELMO1,SLCO2B1,CPN1,MLKL,MARCO,ITM2B,PLXNC1,SPOCK3,ITGB2,PREX1,RXRA,TNFAIP8L2,NCAM2,DOCK2,VMP1,CSF3R,THRB,RAC2
7.049e-03	-4.95	GPR173 (G protein-coupled receptor 173)	protein interactions	54328	49	2	19454	50	UNC93B1,CMTM6
7.049e-03	-4.95	ZNHIT3 (zinc finger HIT-type containing 3)	protein interactions	9326	49	2	19454	50	THRB,RXRA
7.049e-03	-4.95	MCRIP1 (MAPK regulated corepressor interacting protein 1)	protein interactions	348262	49	2	19454	50	RBM47,P2RY6
7.103e-03	-4.95	T cell selection	biological process	GO:0045058	47	2	18204	49	CD74,DOCK2
7.103e-03	-4.95	regulation of erythrocyte differentiation	biological process	GO:0045646	47	2	18204	49	ZFP36L1,INPP5D
7.116e-03	-4.95	zf-C4	pfam domains	PF00105	46	2	17795	49	RXRA,THRB
7.135e-03	-4.94	TMEM43 (transmembrane protein 43)	protein interactions	79188	153	3	19454	50	P2RY6,RMC1,UNC93B1
7.145e-03	-4.94	Nuclear_hrmn_rcpt	interpro domains	IPR001723	47	2	18521	50	RXRA,THRB
7.147e-03	-4.94	mouth	COSMIC cancer mutations	mouth	9004	32	16828	44	CSF3R,DOCK2,NCAM2,PLEK,RBM47,GAB1,MFNG,RAC2,SMPD4,PSAP,DAPP1,CSF1R,RASGRP2,PLXNC1,ABR,RXRA,PREX1,ITGB2,SPOCK3,MAP3K11,CPN1,SLCO2B1,ZFP36L1,CD74,PLXND1,MYO1F,HCK,DPYD,ENTPD1,ANKRD44,ELMO1,ITGAX
7.163e-03	-4.94	late endosome	cellular component	GO:0005770	312	4	19108	47	CD74,PSAP,RMC1,CD68
7.199e-03	-4.93	lung-carcinoma	COSMIC cancer mutations	lung-carcinoma	4255	19	16828	44	ITGB2,ITGAX,ADAM33,PREX1,ANKRD44,SNX17,CSF1R,RASGRP2,DPYD,HCK,GAB1,MFNG,RAC2,VMP1,THRB,CPN1,MAP3K11,MLKL,CSF3R
7.230e-03	-4.93	cytokine binding	molecular function	GO:0019955	146	3	18094	49	CSF1R,CSF3R,CD74
7.246e-03	-4.93	leukocyte chemotaxis	biological process	GO:0030595	147	3	18204	49	CSF3R,PREX1,ITGB2
7.252e-03	-4.93	Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour	COSMIC cancer mutations	Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour	7434	28	16828	44	HCK,DPYD,PLXND1,SNX17,MYO1F,ANKRD44,P2RY6,ENTPD1,ELMO1,ADAM33,ITGAX,SLCO2B1,MLKL,MAP3K11,CPN1,CD68,ZFP36L1,MARCO,PLXNC1,DAPP1,PSAP,CSF1R,PREX1,ABR,CSF3R,DOCK2,GAB1,MFNG
7.313e-03	-4.92	Integrin-mediated Cell Adhesion	WikiPathways	WP185	103	3	5310	21	RAC2,ITGB2,ITGAX
7.399e-03	-4.91	coronary vasculature development	biological process	GO:0060976	48	2	18204	49	PLXND1,SNX17
7.423e-03	-4.90	PCNA (proliferating cell nuclear antigen)	protein interactions	5111	477	5	19454	50	UNC93B1,RMC1,CMTM6,CYFIP1,CD74
7.443e-03	-4.90	Nucl_hrmn_rcpt_lig-bd	interpro domains	IPR000536	48	2	18521	50	THRB,RXRA
7.443e-03	-4.90	Kazal_dom	interpro domains	IPR002350	48	2	18521	50	SLCO2B1,SPOCK3
7.443e-03	-4.90	NHR-like_dom_sf	interpro domains	IPR035500	48	2	18521	50	RXRA,THRB
7.519e-03	-4.89	positive regulation of leukocyte migration	biological process	GO:0002687	149	3	18204	49	CD74,RAC2,CSF1R
7.597e-03	-4.88	thyroid	COSMIC cancer mutations	thyroid	9867	34	16828	44	PLXNC1,RASGRP2,CSF1R,PSAP,SPOCK3,ITGB2,PREX1,TNFAIP8L2,RXRA,ABR,NCAM2,VMP1,DOCK2,CSF3R,THRB,RAC2,GAB1,MFNG,RBM47,PLEK,ANKRD44,DPYD,SNX17,MYO1F,PLXND1,SH2B3,ITGAX,ADAM33,ELMO1,SLCO2B1,MAP3K11,CD74,ZFP36L1,MARCO
7.607e-03	-4.88	positive regulation of cellular process	biological process	GO:0048522	5719	24	18204	49	VMP1,CD74,ZFP36L1,GAB1,P2RY6,HCK,UNC93B1,PLXND1,DOCK2,MARCO,ITGAX,RXRA,THRB,MFNG,PLEK,RAC2,PREX1,ITGB2,MAP3K11,CSF1R,INPP5D,CYFIP1,RBM47,PLXNC1
7.617e-03	-4.88	CD247 (CD247 molecule)	protein interactions	919	51	2	19454	50	SH2B3,DOCK2
7.634e-03	-4.88	tertiary granule	cellular component	GO:0070820	164	3	19108	47	ITGB2,ITGAX,CYFIP1
7.691e-03	-4.87	Grip1 (glutamate receptor interacting protein 1)	protein interactions	74053	3	1	19454	50	RXRA
7.700e-03	-4.87	platelet aggregation	biological process	GO:0070527	49	2	18204	49	ENTPD1,PLEK
7.729e-03	-4.86	Hormone_recep	pfam domains	PF00104	48	2	17795	49	RXRA,THRB
7.909e-03	-4.84	EVI5 (ecotropic viral integration site 5)	protein interactions	7813	52	2	19454	50	P2RY6,UNC93B1
7.909e-03	-4.84	ATP5F1E (ATP synthase F1 subunit epsilon)	protein interactions	514	52	2	19454	50	UNC93B1,P2RY6
7.928e-03	-4.84	COG6 (component of oligomeric golgi complex 6)	protein interactions	57511	159	3	19454	50	P2RY6,CD68,UNC93B1
7.928e-03	-4.84	STYK1 (serine/threonine/tyrosine kinase 1)	protein interactions	55359	159	3	19454	50	MYO1F,GAB1,SMPD4
7.941e-03	-4.84	cellular response to insulin stimulus	biological process	GO:0032869	152	3	18204	49	GAB1,ZFP36L1,CYFIP1
8.007e-03	-4.83	mRNA transcription	biological process	GO:0009299	50	2	18204	49	RXRA,THRB
8.007e-03	-4.83	antigen processing and presentation of exogenous antigen	biological process	GO:0019884	50	2	18204	49	UNC93B1,CD74
8.021e-03	-4.83	YWHAZ (tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein zeta)	protein interactions	7534	1138	8	19454	50	SH2B3,ITGB2,CYFIP1,GAB1,CD74,ZFP36L1,NCAM2,MAP3K11
8.054e-03	-4.82	beta-alanine metabolic process	biological process	GO:0019482	3	1	18204	49	DPYD
8.054e-03	-4.82	septum transversum development	biological process	GO:0003343	3	1	18204	49	ZFP36L1
8.054e-03	-4.82	response to raffinose	biological process	GO:1901545	3	1	18204	49	ZFP36L1
8.054e-03	-4.82	regulation of macrophage migration inhibitory factor signaling pathway	biological process	GO:2000446	3	1	18204	49	CD74
8.054e-03	-4.82	uracil metabolic process	biological process	GO:0019860	3	1	18204	49	DPYD
8.054e-03	-4.82	positive regulation of ATPase-coupled calcium transmembrane transporter activity	biological process	GO:1901896	3	1	18204	49	VMP1
8.054e-03	-4.82	regulation of translation at postsynapse, modulating synaptic transmission	biological process	GO:0099578	3	1	18204	49	CYFIP1
8.054e-03	-4.82	proepicardium development	biological process	GO:0003342	3	1	18204	49	ZFP36L1
8.054e-03	-4.82	cellular response to raffinose	biological process	GO:0097403	3	1	18204	49	ZFP36L1
8.054e-03	-4.82	courtship behavior	biological process	GO:0007619	3	1	18204	49	THRB
8.054e-03	-4.82	leukocyte migration involved in immune response	biological process	GO:0002522	3	1	18204	49	HCK
8.054e-03	-4.82	thymine metabolic process	biological process	GO:0019859	3	1	18204	49	DPYD
8.054e-03	-4.82	thyroid hormone mediated signaling pathway	biological process	GO:0002154	3	1	18204	49	THRB
8.054e-03	-4.82	thymine catabolic process	biological process	GO:0006210	3	1	18204	49	DPYD
8.054e-03	-4.82	regulation of neutrophil differentiation	biological process	GO:0045658	3	1	18204	49	INPP5D
8.054e-03	-4.82	monocyte homeostasis	biological process	GO:0035702	3	1	18204	49	SH2B3
8.054e-03	-4.82	membrane raft polarization	biological process	GO:0001766	3	1	18204	49	DOCK2
8.054e-03	-4.82	purine nucleobase catabolic process	biological process	GO:0006145	3	1	18204	49	DPYD
8.054e-03	-4.82	myeloid dendritic cell activation involved in immune response	biological process	GO:0002277	3	1	18204	49	DOCK2
8.054e-03	-4.82	positive regulation of intracellular mRNA localization	biological process	GO:1904582	3	1	18204	49	ZFP36L1
8.077e-03	-4.82	regulation of ERK1 and ERK2 cascade	biological process	GO:0070372	295	4	18204	49	CSF1R,MARCO,P2RY6,CD74
8.078e-03	-4.82	SNX17/27/31-like	interpro domains	IPR037831	3	1	18521	50	SNX17
8.078e-03	-4.82	FYB1/2-like	interpro domains	IPR043443	3	1	18521	50	FYB1
8.078e-03	-4.82	LAMP_CS	interpro domains	IPR018134	3	1	18521	50	CD68
8.078e-03	-4.82	Fringe	interpro domains	IPR017374	3	1	18521	50	MFNG
8.078e-03	-4.82	SapB_1	interpro domains	IPR007856	3	1	18521	50	PSAP
8.078e-03	-4.82	ITM2	interpro domains	IPR040145	3	1	18521	50	ITM2B
8.078e-03	-4.82	Saposin	interpro domains	IPR008373	3	1	18521	50	PSAP
8.078e-03	-4.82	Phe_ZIP	interpro domains	IPR015012	3	1	18521	50	SH2B3
8.078e-03	-4.82	ZFP36-like	interpro domains	IPR045877	3	1	18521	50	ZFP36L1
8.078e-03	-4.82	ITGAX-like_Ig_3	interpro domains	IPR048633	3	1	18521	50	ITGAX
8.078e-03	-4.82	hSH3	interpro domains	IPR029294	3	1	18521	50	FYB1
8.078e-03	-4.82	MLK1-3_SH3	interpro domains	IPR035779	3	1	18521	50	MAP3K11
8.078e-03	-4.82	SAP_A	interpro domains	IPR003119	3	1	18521	50	PSAP
8.078e-03	-4.82	Phe_ZIP_sf	interpro domains	IPR036290	3	1	18521	50	SH2B3
8.078e-03	-4.82	ELMO_ARM	interpro domains	IPR024574	3	1	18521	50	ELMO1
8.078e-03	-4.82	SH2B	interpro domains	IPR030523	3	1	18521	50	SH2B3
8.085e-03	-4.82	leukocyte proliferation	biological process	GO:0070661	153	3	18204	49	RAC2,DOCK2,CSF1R
8.103e-03	-4.82	ganglioside GT1b binding	molecular function	GO:1905576	3	1	18094	49	PSAP
8.103e-03	-4.82	apyrase activity	molecular function	GO:0004050	3	1	18094	49	ENTPD1
8.103e-03	-4.82	O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity	molecular function	GO:0033829	3	1	18094	49	MFNG
8.103e-03	-4.82	vitamin D response element binding	molecular function	GO:0070644	3	1	18094	49	RXRA
8.103e-03	-4.82	G protein-coupled ADP receptor activity	molecular function	GO:0001621	3	1	18094	49	P2RY6
8.103e-03	-4.82	ganglioside GM1 binding	molecular function	GO:1905573	3	1	18094	49	PSAP
8.103e-03	-4.82	ICAM-3 receptor activity	molecular function	GO:0030369	3	1	18094	49	ITGB2
8.103e-03	-4.82	G protein-coupled UTP receptor activity	molecular function	GO:0045030	3	1	18094	49	P2RY6
8.103e-03	-4.82	DNA binding domain binding	molecular function	GO:0050692	3	1	18094	49	RXRA
8.206e-03	-4.80	CLEC7A (C-type lectin domain containing 7A)	protein interactions	64581	53	2	19454	50	ADAM33,CD74
8.206e-03	-4.80	FCGR2A (Fc gamma receptor IIa)	protein interactions	2212	53	2	19454	50	ADAM33,HCK
8.238e-03	-4.80	Phe_ZIP	pfam domains	PF08916	3	1	17795	49	SH2B3
8.238e-03	-4.80	SapA	pfam domains	PF02199	3	1	17795	49	PSAP
8.238e-03	-4.80	ELMO_ARM	pfam domains	PF11841	3	1	17795	49	ELMO1
8.238e-03	-4.80	SapB_1	pfam domains	PF05184	3	1	17795	49	PSAP
8.238e-03	-4.80	hSH3	pfam domains	PF14603	3	1	17795	49	FYB1
8.238e-03	-4.80	ITGAX-like_Ig_3	pfam domains	PF21520	3	1	17795	49	ITGAX
8.293e-03	-4.79	lung-carcinoma-small_cell_carcinoma	COSMIC cancer mutations	lung-carcinoma-small_cell_carcinoma	9908	34	16828	44	CSF1R,PSAP,PLXNC1,RASGRP2,ABR,PREX1,ITGB2,SPOCK3,THRB,CSF3R,DOCK2,VMP1,NCAM2,RBM47,GAB1,MFNG,SMPD4,RAC2,MYO1F,SNX17,PLXND1,HCK,DPYD,P2RY6,ANKRD44,ADAM33,ELMO1,ITGAX,SH2B3,CPN1,MLKL,MAP3K11,SLCO2B1,MARCO
8.320e-03	-4.79	regulation of bone remodeling	biological process	GO:0046850	51	2	18204	49	CSF1R,INPP5D
8.377e-03	-4.78	myeloid leukocyte activation	biological process	GO:0002274	155	3	18204	49	DOCK2,ITGB2,PREX1
8.382e-03	-4.78	small_cell_carcinoma	COSMIC cancer mutations	small_cell_carcinoma	9913	34	16828	44	THRB,CSF3R,VMP1,DOCK2,NCAM2,RBM47,GAB1,MFNG,SMPD4,RAC2,CSF1R,PSAP,PLXNC1,RASGRP2,ABR,PREX1,ITGB2,SPOCK3,CPN1,MLKL,MAP3K11,SLCO2B1,MARCO,SNX17,MYO1F,PLXND1,DPYD,HCK,ANKRD44,P2RY6,ADAM33,ELMO1,ITGAX,SH2B3
8.390e-03	-4.78	regulation of biological quality	biological process	GO:0065008	2936	15	18204	49	HCK,ENTPD1,SH2B3,PREX1,ITGB2,THRB,PLEK,ZFP36L1,VMP1,PLXNC1,RBM47,PLXND1,CSF1R,CMTM6,CYFIP1
8.401e-03	-4.78	CYTOFMRPINTP	prints domains	PR01698	2	1	5227	22	CYFIP1
8.401e-03	-4.78	NCAMFAMILY	prints domains	PR01838	2	1	5227	22	NCAM2
8.484e-03	-4.77	GRAMD1A (GRAM domain containing 1A)	protein interactions	57655	163	3	19454	50	CD74,P2RY6,UNC93B1
8.484e-03	-4.77	DNAJB12 (DnaJ heat shock protein family (Hsp40) member B12)	protein interactions	54788	163	3	19454	50	UNC93B1,P2RY6,CD74
8.497e-03	-4.77	SEC62 (SEC62 homolog, preprotein translocation factor)	protein interactions	7095	493	5	19454	50	UNC93B1,MFNG,P2RY6,VMP1,SMPD4
8.507e-03	-4.77	LCP2 (lymphocyte cytosolic protein 2)	protein interactions	3937	54	2	19454	50	HCK,FYB1
8.525e-03	-4.76	protein autophosphorylation	biological process	GO:0046777	156	3	18204	49	MAP3K11,CSF1R,HCK
8.604e-03	-4.76	cell motility	biological process	GO:0048870	1101	8	18204	49	CSF3R,GAB1,ELMO1,ITGB2,DOCK2,PREX1,PLXND1,HCK
8.639e-03	-4.75	positive regulation of MAPK cascade	biological process	GO:0043410	473	5	18204	49	MARCO,CSF1R,CD74,P2RY6,MAP3K11
8.672e-03	-4.75	protein complex involved in cell adhesion	cellular component	GO:0098636	57	2	19108	47	ITGB2,ITGAX
8.689e-03	-4.75	urinary_tract-bladder-carcinoma-transitional_cell_carcinoma	COSMIC cancer mutations	urinary_tract-bladder-carcinoma-transitional_cell_carcinoma	6040	24	16828	44	MARCO,ITM2B,ZFP36L1,SLCO2B1,ADAM33,ELMO1,ANKRD44,MYO1F,SNX17,PLXND1,HCK,DPYD,MFNG,SMPD4,RBM47,DOCK2,VMP1,CSF3R,SPOCK3,RXRA,ABR,PREX1,PLXNC1,RASGRP2
8.729e-03	-4.74	transitional_cell_carcinoma	COSMIC cancer mutations	transitional_cell_carcinoma	6042	24	16828	44	SLCO2B1,MARCO,ITM2B,ZFP36L1,ANKRD44,MYO1F,SNX17,PLXND1,HCK,DPYD,ADAM33,ELMO1,VMP1,DOCK2,CSF3R,MFNG,SMPD4,RBM47,PLXNC1,RASGRP2,SPOCK3,RXRA,ABR,PREX1
8.739e-03	-4.74	nuclear receptor activity	molecular function	GO:0004879	52	2	18094	49	RXRA,THRB
8.755e-03	-4.74	immune response-activating signaling pathway	biological process	GO:0002757	302	4	18204	49	FYB1,HCK,UNC93B1,INPP5D
8.771e-03	-4.74	RASA1 (RAS p21 protein activator 1)	protein interactions	5921	165	3	19454	50	CSF1R,GAB1,HCK
8.771e-03	-4.74	haematopoietic_and_lymphoid_tissue-haematopoietic_neoplasm-myeloproliferative_neoplasm	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue-haematopoietic_neoplasm-myeloproliferative_neoplasm	54	2	16828	44	SH2B3,CSF3R
8.771e-03	-4.74	myeloproliferative_neoplasm	COSMIC cancer mutations	myeloproliferative_neoplasm	54	2	16828	44	SH2B3,CSF3R
8.789e-03	-4.73	regulation of MAPK cascade	biological process	GO:0043408	669	6	18204	49	CSF1R,P2RY6,CD74,MARCO,SH2B3,MAP3K11
8.814e-03	-4.73	DOCK1 (dedicator of cytokinesis 1)	protein interactions	1793	55	2	19454	50	ELMO1,RAC2
8.843e-03	-4.73	LGALS1 (galectin 1)	protein interactions	3956	317	4	19454	50	RAC2,PLXND1,HCK,CD68
8.915e-03	-4.72	positive regulation of signal transduction	biological process	GO:0009967	1593	10	18204	49	MARCO,RBM47,MAP3K11,RXRA,THRB,MFNG,CSF1R,CYFIP1,P2RY6,CD74
8.917e-03	-4.72	TBL2 (transducin beta like 2)	protein interactions	26608	166	3	19454	50	UNC93B1,P2RY6,RAC2
8.917e-03	-4.72	CPD (carboxypeptidase D)	protein interactions	1362	166	3	19454	50	CSF1R,CPN1,RAC2
8.917e-03	-4.72	STT3A (STT3 oligosaccharyltransferase complex catalytic subunit A)	protein interactions	3703	166	3	19454	50	UNC93B1,P2RY6,RAC2
8.926e-03	-4.72	CBL (Cbl proto-oncogene)	protein interactions	867	499	5	19454	50	HCK,CSF1R,INPP5D,FYB1,MAP3K11
8.962e-03	-4.71	regulation of platelet activation	biological process	GO:0010543	53	2	18204	49	PLEK,SH2B3
8.962e-03	-4.71	regulation of lamellipodium organization	biological process	GO:1902743	53	2	18204	49	RAC2,CYFIP1
8.975e-03	-4.71	lung-right_upper_lobe-carcinoma-adenocarcinoma	COSMIC cancer mutations	lung-right_upper_lobe-carcinoma-adenocarcinoma	10376	35	16828	44	PREX1,TNFAIP8L2,ABR,SPOCK3,ITGB2,PLXNC1,RASGRP2,CSF1R,PSAP,PLEK,SMPD4,RAC2,GAB1,CSF3R,THRB,NCAM2,VMP1,DOCK2,ADAM33,ELMO1,ITGAX,DPYD,HCK,MYO1F,SNX17,PLXND1,ANKRD44,P2RY6,ENTPD1,ZFP36L1,MARCO,ITM2B,SLCO2B1,CPN1,MLKL
8.975e-03	-4.71	right_upper_lobe	COSMIC cancer mutations	right_upper_lobe	10376	35	16828	44	CPN1,MLKL,SLCO2B1,MARCO,ITM2B,ZFP36L1,MYO1F,SNX17,PLXND1,HCK,DPYD,ENTPD1,ANKRD44,P2RY6,ADAM33,ELMO1,ITGAX,THRB,CSF3R,VMP1,DOCK2,NCAM2,PLEK,GAB1,RAC2,SMPD4,CSF1R,PSAP,PLXNC1,RASGRP2,TNFAIP8L2,ABR,PREX1,ITGB2,SPOCK3
9.063e-03	-4.70	CIP2A (cellular inhibitor of PP2A)	protein interactions	57650	167	3	19454	50	P2RY6,MFNG,UNC93B1
9.063e-03	-4.70	MACO1 (macoilin 1)	protein interactions	55219	167	3	19454	50	UNC93B1,RAC2,P2RY6
9.066e-03	-4.70	ligand-activated transcription factor activity	molecular function	GO:0098531	53	2	18094	49	THRB,RXRA
9.095e-03	-4.70	-	gene3d domains	3.30.70.20	3	1	14470	44	DPYD
9.095e-03	-4.70	-	gene3d domains	1.20.80.60	3	1	14470	44	SNX17
9.095e-03	-4.70	-	gene3d domains	6.10.250.810	3	1	14470	44	ELMO1
9.095e-03	-4.70	-	gene3d domains	6.10.140.110	3	1	14470	44	SH2B3
9.212e-03	-4.69	GAB1 (GRB2 associated binding protein 1)	protein interactions	2549	168	3	19454	50	INPP5D,GAB1,HCK
9.212e-03	-4.69	KLK10 (kallikrein related peptidase 10)	protein interactions	5655	168	3	19454	50	RAC2,ITGB2,MYO1F
9.212e-03	-4.69	NUP133 (nucleoporin 133)	protein interactions	55746	168	3	19454	50	UNC93B1,P2RY6,PSAP
9.290e-03	-4.68	regulation of alcohol biosynthetic process	biological process	GO:1902930	54	2	18204	49	P2RY6,PLEK
9.301e-03	-4.68	regulation of response to external stimulus	biological process	GO:0032101	1116	8	18204	49	CSF1R,CD74,RBM47,UNC93B1,HCK,TNFAIP8L2,RAC2,SH2B3
9.328e-03	-4.67	Retinoid X Receptor	gene3d domains	1.10.565.10	48	2	14470	44	RXRA,THRB
9.329e-03	-4.67	ITGB1 (integrin subunit beta 1)	protein interactions	3688	322	4	19454	50	SNX17,RXRA,P2RY6,RAC2
9.429e-03	-4.66	ATP2A2 (ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2)	protein interactions	488	323	4	19454	50	RMC1,UNC93B1,VMP1,P2RY6
9.442e-03	-4.66	ICAM2 (intercellular adhesion molecule 2)	protein interactions	3384	57	2	19454	50	ITM2B,ITGB2
9.442e-03	-4.66	CSF1R (colony stimulating factor 1 receptor)	protein interactions	1436	57	2	19454	50	INPP5D,CSF1R
9.442e-03	-4.66	EVI5L (ecotropic viral integration site 5 like)	protein interactions	115704	57	2	19454	50	UNC93B1,P2RY6
9.442e-03	-4.66	FXN (frataxin)	protein interactions	2395	57	2	19454	50	DAPP1,PSAP
9.442e-03	-4.66	KNG1 (kininogen 1)	protein interactions	3827	57	2	19454	50	ITGB2,CPN1
9.513e-03	-4.66	GLMN (glomulin, FKBP associated protein)	protein interactions	11146	170	3	19454	50	UNC93B1,MFNG,PSAP
9.513e-03	-4.66	PIK3C2A (phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 alpha)	protein interactions	5286	170	3	19454	50	RBM47,RAC2,P2RY6
9.513e-03	-4.66	BZW1 (basic leucine zipper and W2 domains 1)	protein interactions	9689	170	3	19454	50	PREX1,P2RY6,UNC93B1
9.521e-03	-4.65	RHOU (ras homolog family member U)	protein interactions	58480	507	5	19454	50	GAB1,CYFIP1,ITM2B,PLEK,SNX17
9.579e-03	-4.65	human chr11q13.4	chromosome location	human chr11q13.4	77	2	26134	50	P2RY6,SLCO2B1
9.606e-03	-4.65	receptor-mediated endocytosis	biological process	GO:0006898	163	3	18204	49	MARCO,SNX17,ITGB2
9.630e-03	-4.64	CYB5R3 (cytochrome b5 reductase 3)	protein interactions	1727	325	4	19454	50	RAC2,ADAM33,VMP1,UNC93B1
9.665e-03	-4.64	PLSCR1 (phospholipid scramblase 1)	protein interactions	5359	171	3	19454	50	MFNG,DOCK2,P2RY6
9.680e-03	-4.64	response to other organism	biological process	GO:0051707	1363	9	18204	49	MLKL,CD68,CSF1R,CD74,TNFAIP8L2,ITGAX,UNC93B1,HCK,MARCO
9.758e-03	-4.63	brainstem	COSMIC cancer mutations	brainstem	3102	15	16828	44	ELMO1,PREX1,ITGAX,SPOCK3,CSF1R,DPYD,RASGRP2,ANKRD44,RBM47,GAB1,SMPD4,THRB,SLCO2B1,DOCK2,NCAM2
9.763e-03	-4.63	NAXE (NAD(P)HX epimerase)	protein interactions	128240	58	2	19454	50	DPYD,SNX17
9.763e-03	-4.63	SELENOF (selenoprotein F)	protein interactions	9403	58	2	19454	50	P2RY6,UNC93B1
9.763e-03	-4.63	MAP3K11 (mitogen-activated protein kinase kinase kinase 11)	protein interactions	4296	58	2	19454	50	MAP3K11,RAC2
9.767e-03	-4.63	positive regulation of leukocyte proliferation	biological process	GO:0070665	164	3	18204	49	CSF1R,CD74,RAC2
9.767e-03	-4.63	negative regulation of lymphocyte activation	biological process	GO:0051250	164	3	18204	49	INPP5D,TNFAIP8L2,CD74
9.803e-03	-4.63	central region of growth cone	cellular component	GO:0090724	4	1	19108	47	CYFIP1
9.806e-03	-4.62	haematopoietic_and_lymphoid_tissue-haematopoietic_neoplasm-acute_myeloid_leukaemia	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue-haematopoietic_neoplasm-acute_myeloid_leukaemia	10418	35	16828	44	PLXND1,SNX17,MYO1F,DPYD,ENTPD1,ANKRD44,P2RY6,ELMO1,ADAM33,ITGAX,SH2B3,MAP3K11,MLKL,CPN1,SLCO2B1,MARCO,CD68,CD74,DAPP1,PSAP,CSF1R,PLXNC1,CMTM6,RXRA,PREX1,SPOCK3,THRB,CSF3R,DOCK2,VMP1,NCAM2,PLEK,GAB1,SMPD4,RAC2
9.806e-03	-4.62	acute_myeloid_leukaemia	COSMIC cancer mutations	acute_myeloid_leukaemia	10418	35	16828	44	NCAM2,DOCK2,VMP1,CSF3R,THRB,SMPD4,RAC2,GAB1,PLEK,CMTM6,PLXNC1,CSF1R,DAPP1,PSAP,SPOCK3,PREX1,RXRA,SLCO2B1,CPN1,MAP3K11,MLKL,CD74,CD68,MARCO,P2RY6,ANKRD44,ENTPD1,DPYD,MYO1F,SNX17,PLXND1,ITGAX,SH2B3,ADAM33,ELMO1
9.814e-03	-4.62	response to external biotic stimulus	biological process	GO:0043207	1366	9	18204	49	ITGAX,TNFAIP8L2,MARCO,UNC93B1,HCK,CD74,MLKL,CSF1R,CD68
9.838e-03	-4.62	leading edge membrane	cellular component	GO:0031256	180	3	19108	47	PLXND1,PLEK,RASGRP2
9.881e-03	-4.62	ficolin-1-rich granule membrane	cellular component	GO:0101003	61	2	19108	47	ITGB2,ITGAX
9.898e-03	-4.62	upper_aerodigestive_tract-larynx-carcinoma-squamous_cell_carcinoma	COSMIC cancer mutations	upper_aerodigestive_tract-larynx-carcinoma-squamous_cell_carcinoma	1946	11	16828	44	DOCK2,NCAM2,ANKRD44,CPN1,PLXND1,PLXNC1,DPYD,GAB1,RAC2,MARCO,PREX1
9.907e-03	-4.61	KPNB1 (karyopherin subunit beta 1)	protein interactions	3837	512	5	19454	50	UNC93B1,THRB,CD74,SMPD4,P2RY6
9.956e-03	-4.61	UTP and CTP dephosphorylation I	BIOCYC pathways	META_PWY-7185	3	1	902	3	ENTPD1
9.956e-03	-4.61	UTP and CTP dephosphorylation II	BIOCYC pathways	META_PWY-7177	3	1	902	3	ENTPD1
9.956e-03	-4.61	uracil degradation I (reductive)	BIOCYC pathways	META_PWY-3982	3	1	902	3	DPYD
9.956e-03	-4.61	thymine degradation	BIOCYC pathways	HUMAN_PWY-6430	3	1	902	3	DPYD
9.956e-03	-4.61	uracil degradation	BIOCYC pathways	HUMAN_PWY-3982	3	1	902	3	DPYD
9.964e-03	-4.61	leukocyte cell-cell adhesion	biological process	GO:0007159	56	2	18204	49	ITGB2,RAC2
9.972e-03	-4.61	larynx	COSMIC cancer mutations	larynx	1948	11	16828	44	PREX1,MARCO,RAC2,GAB1,PLXNC1,DPYD,CPN1,PLXND1,NCAM2,ANKRD44,DOCK2
1.001e-02	-4.60	central_nervous_system-brain-glioma-astrocytoma_Grade_III	COSMIC cancer mutations	central_nervous_system-brain-glioma-astrocytoma_Grade_III	1419	9	16828	44	PLXNC1,DPYD,NCAM2,DOCK2,PLEK,ELMO1,SMPD4,RAC2,CD74
1.002e-02	-4.60	Znf_NHR/GATA	interpro domains	IPR013088	56	2	18521	50	RXRA,THRB
1.003e-02	-4.60	regulation of transport	biological process	GO:0051049	1621	10	18204	49	P2RY6,CYFIP1,CD74,DOCK2,SNX17,VMP1,ITGB2,RAC2,RXRA,HCK
1.009e-02	-4.60	CNNM4 (cyclin and CBS domain divalent metal cation transport mediator 4)	protein interactions	26504	59	2	19454	50	UNC93B1,P2RY6
1.009e-02	-4.60	lymphocyte mediated immunity	biological process	GO:0002449	166	3	18204	49	CD74,INPP5D,UNC93B1
1.011e-02	-4.59	Nuclear Receptors	WikiPathways	WP170	39	2	5310	21	RXRA,THRB
1.013e-02	-4.59	SURF4 (surfeit 4)	protein interactions	6836	174	3	19454	50	PSAP,P2RY6,UNC93B1
1.013e-02	-4.59	SLC1A1 (solute carrier family 1 member 1)	protein interactions	6505	174	3	19454	50	SNX17,CMTM6,VMP1
1.014e-02	-4.59	anion binding	molecular function	GO:0043168	2412	13	18094	49	RXRA,RAC2,DAPP1,HCK,PLEK,MYO1F,ENTPD1,MLKL,CSF1R,ITM2B,DPYD,MAP3K11,PSAP
1.019e-02	-4.59	specific granule lumen	cellular component	GO:0035580	62	2	19108	47	CYFIP1,DOCK2
1.024e-02	-4.58	FCGR1BP (Fc gamma receptor Ib, pseudogene)	protein interactions	2210	4	1	19454	50	INPP5D
1.024e-02	-4.58	Map6 (microtubule-associated protein 6)	protein interactions	29457	4	1	19454	50	PLXND1
1.024e-02	-4.58	Hdac2 (histone deacetylase 2)	protein interactions	15182	4	1	19454	50	THRB
1.024e-02	-4.58	EPGN (epithelial mitogen)	protein interactions	255324	4	1	19454	50	ADAM33
1.030e-02	-4.58	nucleoside-triphosphatase regulator activity	molecular function	GO:0060589	491	5	18094	49	PREX1,RASGRP2,ABR,DOCK2,ELMO1
1.030e-02	-4.58	GTPase regulator activity	molecular function	GO:0030695	491	5	18094	49	RASGRP2,PREX1,DOCK2,ABR,ELMO1
1.031e-02	-4.57	regulation of myeloid leukocyte mediated immunity	biological process	GO:0002886	57	2	18204	49	RAC2,ITGB2
1.035e-02	-4.57	SEC63 (SEC63 homolog, protein translocation regulator)	protein interactions	11231	332	4	19454	50	RBM47,P2RY6,SMPD4,UNC93B1
1.042e-02	-4.56	haematopoietic_and_lymphoid_tissue-other-idiopathic_erythrocytosis	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue-other-idiopathic_erythrocytosis	4	1	16828	44	SH2B3
1.042e-02	-4.56	idiopathic_erythrocytosis	COSMIC cancer mutations	idiopathic_erythrocytosis	4	1	16828	44	SH2B3
1.042e-02	-4.56	DOCK2 (dedicator of cytokinesis 2)	protein interactions	1794	60	2	19454	50	RAC2,ELMO1
1.044e-02	-4.56	ruffle	cellular component	GO:0001726	184	3	19108	47	PLEK,RASGRP2,CYFIP1
1.046e-02	-4.56	SAPA	smart domains	SM00162	3	1	9717	34	PSAP
1.049e-02	-4.56	intestinal_adenocarcinoma	COSMIC cancer mutations	intestinal_adenocarcinoma	7225	27	16828	44	SMPD4,RAC2,GAB1,PLEK,RBM47,DOCK2,VMP1,THRB,SPOCK3,PREX1,ABR,RXRA,RASGRP2,PLXNC1,CSF1R,CD74,ITM2B,SLCO2B1,MLKL,ITGAX,ELMO1,ADAM33,ANKRD44,P2RY6,DPYD,PLXND1,MYO1F
1.049e-02	-4.56	stomach-carcinoma-intestinal_adenocarcinoma	COSMIC cancer mutations	stomach-carcinoma-intestinal_adenocarcinoma	7225	27	16828	44	PLEK,RBM47,SMPD4,RAC2,GAB1,THRB,DOCK2,VMP1,PREX1,ABR,RXRA,SPOCK3,RASGRP2,PLXNC1,CSF1R,ITM2B,CD74,SLCO2B1,MLKL,ELMO1,ADAM33,ITGAX,DPYD,PLXND1,MYO1F,P2RY6,ANKRD44
1.055e-02	-4.55	SAP_A	prosite domains	PS51110	3	1	12186	43	PSAP
1.055e-02	-4.55	LAMP_2	prosite domains	PS00311	3	1	12186	43	CD68
1.056e-02	-4.55	central_nervous_system-brainstem-glioma-astrocytoma_Grade_IV	COSMIC cancer mutations	central_nervous_system-brainstem-glioma-astrocytoma_Grade_IV	2531	13	16828	44	SMPD4,GAB1,NCAM2,DOCK2,SLCO2B1,THRB,ITGAX,PREX1,ELMO1,ANKRD44,RASGRP2,DPYD,CSF1R
1.063e-02	-4.54	positive regulation of phosphorus metabolic process	biological process	GO:0010562	697	6	18204	49	P2RY6,PLEK,MAP3K11,CD74,MARCO,CSF1R
1.063e-02	-4.54	positive regulation of phosphate metabolic process	biological process	GO:0045937	697	6	18204	49	CSF1R,MARCO,CD74,P2RY6,PLEK,MAP3K11
1.069e-02	-4.54	positive regulation of developmental process	biological process	GO:0051094	1385	9	18204	49	PLXNC1,ITGAX,RXRA,PLXND1,INPP5D,CYFIP1,ZFP36L1,GAB1,CD74
1.071e-02	-4.54	small_intestine-carcinoid-endocrine_tumour	COSMIC cancer mutations	small_intestine-carcinoid-endocrine_tumour	175	3	16828	44	PLXND1,CSF1R,VMP1
1.072e-02	-4.54	respiratory burst after phagocytosis	biological process	GO:0045728	4	1	18204	49	HCK
1.072e-02	-4.54	positive regulation of neutrophil degranulation	biological process	GO:0043315	4	1	18204	49	ITGB2
1.072e-02	-4.54	negative regulation of female receptivity	biological process	GO:0007621	4	1	18204	49	THRB
1.072e-02	-4.54	CMP catabolic process	biological process	GO:0006248	4	1	18204	49	DPYD
1.072e-02	-4.54	erythrocyte enucleation	biological process	GO:0043131	4	1	18204	49	RAC2
1.072e-02	-4.54	positive regulation of mast cell proliferation	biological process	GO:0070668	4	1	18204	49	RAC2
1.072e-02	-4.54	dichotomous subdivision of terminal units involved in salivary gland branching	biological process	GO:0060666	4	1	18204	49	PLXND1
1.072e-02	-4.54	regulation of inositol trisphosphate biosynthetic process	biological process	GO:0032960	4	1	18204	49	P2RY6
1.072e-02	-4.54	negative regulation of mature B cell apoptotic process	biological process	GO:0002906	4	1	18204	49	CD74
1.072e-02	-4.54	negative regulation of dendritic cell antigen processing and presentation	biological process	GO:0002605	4	1	18204	49	CD68
1.072e-02	-4.54	macrophage colony-stimulating factor signaling pathway	biological process	GO:0038145	4	1	18204	49	CSF1R
1.072e-02	-4.54	positive regulation of inositol trisphosphate biosynthetic process	biological process	GO:0032962	4	1	18204	49	P2RY6
1.072e-02	-4.54	enucleate erythrocyte maturation	biological process	GO:0043354	4	1	18204	49	RAC2
1.072e-02	-4.54	regulation of mature B cell apoptotic process	biological process	GO:0002905	4	1	18204	49	CD74
1.072e-02	-4.54	positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity	biological process	GO:0031587	4	1	18204	49	P2RY6
1.072e-02	-4.54	regulation of intracellular mRNA localization	biological process	GO:1904580	4	1	18204	49	ZFP36L1
1.072e-02	-4.54	enucleation	biological process	GO:0090601	4	1	18204	49	RAC2
1.072e-02	-4.54	mast cell proliferation	biological process	GO:0070662	4	1	18204	49	RAC2
1.076e-02	-4.53	VTT_dom	interpro domains	IPR032816	4	1	18521	50	VMP1
1.076e-02	-4.53	TNFAIP8_sf	interpro domains	IPR038355	4	1	18521	50	TNFAIP8L2
1.076e-02	-4.53	SapB_2	interpro domains	IPR008138	4	1	18521	50	PSAP
1.076e-02	-4.53	4Fe4S_Fe_S_CS	interpro domains	IPR017900	4	1	18521	50	DPYD
1.076e-02	-4.53	Gab1-4-like	interpro domains	IPR046355	4	1	18521	50	GAB1
1.076e-02	-4.53	TNFAIP8-like	interpro domains	IPR008477	4	1	18521	50	TNFAIP8L2
1.076e-02	-4.53	MLK1-4	interpro domains	IPR016231	4	1	18521	50	MAP3K11
1.076e-02	-4.53	Retinoid-X_rcpt/HNF4	interpro domains	IPR000003	4	1	18521	50	RXRA
1.076e-02	-4.53	ThyrH_rcpt	interpro domains	IPR001728	4	1	18521	50	THRB
1.076e-02	-4.53	CYRIA/CYRIB_Rac1-bd	interpro domains	IPR009828	4	1	18521	50	CYFIP1
1.076e-02	-4.53	IgC2-like_lig-bd	interpro domains	IPR010457	4	1	18521	50	CSF3R
1.076e-02	-4.53	Adaptor_Cbl_N_dom_sf	interpro domains	IPR036537	4	1	18521	50	MLKL
1.076e-02	-4.53	VPS8 (VPS8 subunit of CORVET complex)	protein interactions	23355	61	2	19454	50	P2RY6,UNC93B1
1.079e-02	-4.53	CDP phosphatase activity	molecular function	GO:0036384	4	1	18094	49	ENTPD1
1.079e-02	-4.53	nucleobase binding	molecular function	GO:0002054	4	1	18094	49	DPYD
1.079e-02	-4.53	stem cell factor receptor binding	molecular function	GO:0005173	4	1	18094	49	SH2B3
1.079e-02	-4.53	G protein-coupled pyrimidinergic nucleotide receptor activity	molecular function	GO:0071553	4	1	18094	49	P2RY6
1.079e-02	-4.53	IDP phosphatase activity	molecular function	GO:1990003	4	1	18094	49	ENTPD1
1.081e-02	-4.53	human chr22q13.1	chromosome location	human chr22q13.1	82	2	26134	50	RAC2,MFNG
1.097e-02	-4.51	Lep_receptor_Ig	pfam domains	PF06328	4	1	17795	49	CSF3R
1.097e-02	-4.51	DUF758	pfam domains	PF05527	4	1	17795	49	TNFAIP8L2
1.097e-02	-4.51	SNARE_assoc	pfam domains	PF09335	4	1	17795	49	VMP1
1.097e-02	-4.51	CYRIA-B_Rac1-bd	pfam domains	PF07159	4	1	17795	49	CYFIP1
1.097e-02	-4.51	SapB_2	pfam domains	PF03489	4	1	17795	49	PSAP
1.100e-02	-4.51	NOTCH1 (notch receptor 1)	protein interactions	4851	338	4	19454	50	RAC2,MFNG,RMC1,ANKRD44
1.105e-02	-4.51	haematopoietic_and_lymphoid_tissue-haematopoietic_neoplasm-acute_myeloid_leukaemia_associated_with_MDS	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue-haematopoietic_neoplasm-acute_myeloid_leukaemia_associated_with_MDS	177	3	16828	44	SH2B3,CSF3R,CSF1R
1.105e-02	-4.51	acute_myeloid_leukaemia_associated_with_MDS	COSMIC cancer mutations	acute_myeloid_leukaemia_associated_with_MDS	177	3	16828	44	CSF1R,CSF3R,SH2B3
1.109e-02	-4.50	acute_leukaemia_of_ambiguous_lineage	COSMIC cancer mutations	acute_leukaemia_of_ambiguous_lineage	61	2	16828	44	CSF1R,CSF3R
1.109e-02	-4.50	haematopoietic_and_lymphoid_tissue-haematopoietic_neoplasm-acute_leukaemia_of_ambiguous_lineage	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue-haematopoietic_neoplasm-acute_leukaemia_of_ambiguous_lineage	61	2	16828	44	CSF3R,CSF1R
1.110e-02	-4.50	RNF128 (ring finger protein 128)	protein interactions	79589	62	2	19454	50	ITM2B,SNX17
1.113e-02	-4.50	cell migration	biological process	GO:0016477	921	7	18204	49	PLXND1,GAB1,CSF3R,DOCK2,HCK,ITGB2,PREX1
1.116e-02	-4.50	excitatory synapse	cellular component	GO:0060076	65	2	19108	47	PLXNC1,CYFIP1
1.117e-02	-4.49	ZnF_C4	smart domains	SM00399	46	2	9717	34	RXRA,THRB
1.121e-02	-4.49	YWHAB (tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein beta)	protein interactions	7529	965	7	19454	50	CYFIP1,GAB1,CD74,ITGB2,NCAM2,P2RY6,ZFP36L1
1.122e-02	-4.49	protein kinase binding	molecular function	GO:0019901	701	6	18094	49	MLKL,PLEK,SH2B3,MAP3K11,ITGAX,ITGB2
1.126e-02	-4.49	regulation of lymphocyte activation	biological process	GO:0051249	505	5	18204	49	INPP5D,TNFAIP8L2,ZFP36L1,CD74,RAC2
1.137e-02	-4.48	positive regulation of cytokine-mediated signaling pathway	biological process	GO:0001961	60	2	18204	49	CD74,RBM47
1.140e-02	-4.47	CANX (calnexin)	protein interactions	821	1210	8	19454	50	P2RY6,PSAP,RMC1,UNC93B1,RAC2,SMPD4,CD74,ITM2B
1.141e-02	-4.47	NUCLEAR_REC_DBD_1	prosite domains	PS00031	46	2	12186	43	RXRA,THRB
1.141e-02	-4.47	NUCLEAR_REC_DBD_2	prosite domains	PS51030	46	2	12186	43	THRB,RXRA
1.144e-02	-4.47	PRPS1 (phosphoribosyl pyrophosphate synthetase 1)	protein interactions	5631	182	3	19454	50	RMC1,HCK,P2RY6
1.144e-02	-4.47	RAB32 (RAB32, member RAS oncogene family)	protein interactions	10981	63	2	19454	50	LRMDA,RAC2
1.153e-02	-4.46	response to endogenous stimulus	biological process	GO:0009719	1402	9	18204	49	ITGB2,RXRA,CD68,THRB,CPN1,GAB1,P2RY6,CYFIP1,ZFP36L1
1.161e-02	-4.46	KRTAP1-3 (keratin associated protein 1-3)	protein interactions	81850	183	3	19454	50	HCK,INPP5D,DOCK2
1.164e-02	-4.45	positive regulation of supramolecular fiber organization	biological process	GO:1902905	175	3	18204	49	HCK,CYFIP1,PLEK
1.164e-02	-4.45	regulation of interleukin-6 production	biological process	GO:0032675	175	3	18204	49	CD74,UNC93B1,INPP5D
1.174e-02	-4.44	aorta development	biological process	GO:0035904	61	2	18204	49	PLXND1,SNX17
1.174e-02	-4.44	negative regulation of G protein-coupled receptor signaling pathway	biological process	GO:0045744	61	2	18204	49	PLEK,SH2B3
1.178e-02	-4.44	SAAL1 (serum amyloid A like 1)	protein interactions	113174	184	3	19454	50	CD68,UNC93B1,P2RY6
1.179e-02	-4.44	AGPAT2 (1-acylglycerol-3-phosphate O-acyltransferase 2)	protein interactions	10555	64	2	19454	50	UNC93B1,P2RY6
1.182e-02	-4.44	adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains	biological process	GO:0002460	176	3	18204	49	UNC93B1,INPP5D,CD74
1.184e-02	-4.44	response to biotic stimulus	biological process	GO:0009607	1408	9	18204	49	MLKL,CSF1R,CD68,CD74,ITGAX,TNFAIP8L2,MARCO,HCK,UNC93B1
1.192e-02	-4.43	plasma membrane region	cellular component	GO:0098590	1278	8	19108	47	ITGB2,RASGRP2,PLEK,P2RY6,ENTPD1,SLCO2B1,PLXND1,HCK
1.202e-02	-4.42	PTPN11 (protein tyrosine phosphatase non-receptor type 11)	protein interactions	5781	347	4	19454	50	CSF3R,DAPP1,GAB1,INPP5D
1.208e-02	-4.42	follicular_lymphoma	COSMIC cancer mutations	follicular_lymphoma	1209	8	16828	44	ITGAX,ZFP36L1,RXRA,NCAM2,ENTPD1,DOCK2,HCK,DPYD
1.211e-02	-4.41	Tumor necrosis factor alpha-induced protein 8-like	gene3d domains	1.20.1440.160	4	1	14470	44	TNFAIP8L2
1.211e-02	-4.41	Adaptor protein Cbl, N-terminal domain	gene3d domains	1.20.930.20	4	1	14470	44	MLKL
1.211e-02	-4.41	positive regulation of myeloid leukocyte differentiation	biological process	GO:0002763	62	2	18204	49	ZFP36L1,CD74
1.212e-02	-4.41	HOLI	smart domains	SM00430	48	2	9717	34	RXRA,THRB
1.215e-02	-4.41	COG5 (component of oligomeric golgi complex 5)	protein interactions	10466	65	2	19454	50	P2RY6,UNC93B1
1.220e-02	-4.41	IL-6 signaling pathway	WikiPathways	WP364	43	2	5310	21	GAB1,HCK
1.224e-02	-4.40	Mon1-Ccz1 complex	cellular component	GO:0035658	5	1	19108	47	RMC1
1.224e-02	-4.40	apolipoprotein B mRNA editing enzyme complex	cellular component	GO:0030895	5	1	19108	47	RBM47
1.226e-02	-4.40	SH3_2	pfam domains	PF07653	61	2	17795	49	FYB1,DOCK2
1.227e-02	-4.40	regulation of vesicle-mediated transport	biological process	GO:0060627	516	5	18204	49	SNX17,RAC2,DOCK2,ITGB2,HCK
1.238e-02	-4.39	SHC1 (SHC adaptor protein 1)	protein interactions	6464	350	4	19454	50	CSF3R,CSF1R,INPP5D,GAB1
1.238e-02	-4.39	EPHA2 (EPH receptor A2)	protein interactions	1969	350	4	19454	50	RAC2,GAB1,CSF1R,HCK
1.238e-02	-4.39	NR_LBD	prosite domains	PS51843	48	2	12186	43	RXRA,THRB
1.238e-02	-4.39	KAZAL_2	prosite domains	PS51465	48	2	12186	43	SPOCK3,SLCO2B1
1.248e-02	-4.38	PIGT (phosphatidylinositol glycan anchor biosynthesis class T)	protein interactions	51604	188	3	19454	50	ADAM33,P2RY6,UNC93B1
1.250e-02	-4.38	HLA-DRB3 (major histocompatibility complex, class II, DR beta 3)	protein interactions	3125	66	2	19454	50	ITM2B,CD74
1.254e-02	-4.38	Erythroid Transcription Factor GATA-1, subunit A	gene3d domains	3.30.50.10	56	2	14470	44	RXRA,THRB
1.258e-02	-4.38	SAPOSIN	prints domains	PR01797	3	1	5227	22	PSAP
1.260e-02	-4.37	endosome membrane	cellular component	GO:0010008	569	5	19108	47	ITM2B,CD68,CMTM6,SNX17,RMC1
1.263e-02	-4.37	regulation of immune response	biological process	GO:0050776	944	7	18204	49	HCK,UNC93B1,RBM47,FYB1,ITGB2,INPP5D,CD74
1.270e-02	-4.37	mesothelioma	COSMIC cancer mutations	mesothelioma	4477	19	16828	44	ITGB2,SH2B3,ITGAX,ADAM33,PREX1,ANKRD44,SNX17,CSF1R,HCK,DPYD,RASGRP2,GAB1,MFNG,RAC2,VMP1,CPN1,THRB,MLKL,MAP3K11
1.275e-02	-4.36	regulation of cytoskeleton organization	biological process	GO:0051493	521	5	18204	49	CSF1R,HCK,PREX1,PLEK,CYFIP1
1.279e-02	-4.36	SAMD8 (sterile alpha motif domain containing 8)	protein interactions	142891	5	1	19454	50	MFNG
1.279e-02	-4.36	CPN2 (carboxypeptidase N subunit 2)	protein interactions	1370	5	1	19454	50	CPN1
1.279e-02	-4.36	CEMP1 (cementum protein 1)	protein interactions	752014	5	1	19454	50	PLXNC1
1.279e-02	-4.36	Gab2 (growth factor receptor bound protein 2-associated protein 2)	protein interactions	14389	5	1	19454	50	INPP5D
1.279e-02	-4.36	ORF48 (ORF48)	protein interactions	4961458	5	1	19454	50	ANKRD44
1.287e-02	-4.35	regulation of B cell proliferation	biological process	GO:0030888	64	2	18204	49	INPP5D,CD74
1.287e-02	-4.35	ADAM15 (ADAM metallopeptidase domain 15)	protein interactions	8751	67	2	19454	50	ADAM33,HCK
1.289e-02	-4.35	skin-neck-malignant_melanoma	COSMIC cancer mutations	skin-neck-malignant_melanoma	1223	8	16828	44	CSF1R,CPN1,VMP1,MARCO,ADAM33,PREX1,ITGAX,ITGB2
1.293e-02	-4.35	regulation of cytokine-mediated signaling pathway	biological process	GO:0001959	182	3	18204	49	RBM47,SH2B3,CD74
1.295e-02	-4.35	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-follicular_lymphoma	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-follicular_lymphoma	981	7	16828	44	ENTPD1,DOCK2,NCAM2,HCK,DPYD,ITGAX,RXRA
1.310e-02	-4.34	anatomical structure morphogenesis	biological process	GO:0009653	2225	12	18204	49	UNC93B1,ITGB2,MFNG,THRB,ZFP36L1,CSF3R,GAB1,ITGAX,CSF1R,PLXND1,DOCK2,CYFIP1
1.311e-02	-4.33	DNAJC1 (DnaJ heat shock protein family (Hsp40) member C1)	protein interactions	64215	356	4	19454	50	RAC2,SMPD4,P2RY6,UNC93B1
1.311e-02	-4.33	beta-Alanine Metabolism	SMPDB pathways	SMP0000007	9	1	1369	2	DPYD
1.311e-02	-4.33	GABA-Transaminase Deficiency	SMPDB pathways	SMP0000351	9	1	1369	2	DPYD
1.311e-02	-4.33	Carnosinuria- Carnosinemia	SMPDB pathways	SMP0000493	9	1	1369	2	DPYD
1.320e-02	-4.33	VIPR2 (vasoactive intestinal peptide receptor 2)	protein interactions	7434	192	3	19454	50	UNC93B1,SNX17,CMTM6
1.320e-02	-4.33	UBE3C (ubiquitin protein ligase E3C)	protein interactions	9690	192	3	19454	50	P2RY6,CD74,UNC93B1
1.324e-02	-4.32	SWAP70 (switching B cell complex subunit SWAP70)	protein interactions	23075	68	2	19454	50	RAC2,RMC1
1.324e-02	-4.32	NRBF2 (nuclear receptor binding factor 2)	protein interactions	29982	68	2	19454	50	RXRA,THRB
1.324e-02	-4.32	SLC1A3 (solute carrier family 1 member 3)	protein interactions	6507	68	2	19454	50	CYFIP1,RAC2
1.324e-02	-4.32	GEMIN6 (gem nuclear organelle associated protein 6)	protein interactions	79833	68	2	19454	50	UNC93B1,P2RY6
1.326e-02	-4.32	UTP and CTP dephosphorylation II	BIOCYC pathways	HUMAN_PWY-7177	4	1	902	3	ENTPD1
1.331e-02	-4.32	positive regulation of cytoskeleton organization	biological process	GO:0051495	184	3	18204	49	PLEK,CYFIP1,HCK
1.335e-02	-4.32	Pyrimidine degradation, uracil => beta-alanine, thymine => 3-aminoisobutanoate	KEGG pathways	hsa_M00046	3	1	7161	32	DPYD
1.335e-02	-4.32	Pyrimidine degradation, uracil => beta-alanine, thymine => 3-aminoisobutanoate	KEGG pathways	M00046	3	1	7161	32	DPYD
1.335e-02	-4.32	PGRMC1 (progesterone receptor membrane component 1)	protein interactions	10857	358	4	19454	50	UNC93B1,CD74,VMP1,P2RY6
1.337e-02	-4.31	neck	COSMIC cancer mutations	neck	1231	8	16828	44	PREX1,MARCO,ADAM33,ITGB2,ITGAX,CSF1R,CPN1,VMP1
1.339e-02	-4.31	LTN1 (listerin E3 ubiquitin protein ligase 1)	protein interactions	26046	193	3	19454	50	UNC93B1,P2RY6,CD74
1.339e-02	-4.31	toll-like receptor 7 signaling pathway	biological process	GO:0034154	5	1	18204	49	UNC93B1
1.339e-02	-4.31	T cell antigen processing and presentation	biological process	GO:0002457	5	1	18204	49	UNC93B1
1.339e-02	-4.31	lymphocyte aggregation	biological process	GO:0071593	5	1	18204	49	RAC2
1.339e-02	-4.31	regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity	biological process	GO:0031585	5	1	18204	49	P2RY6
1.339e-02	-4.31	thymidine metabolic process	biological process	GO:0046104	5	1	18204	49	DPYD
1.339e-02	-4.31	pyrimidine ribonucleoside monophosphate catabolic process	biological process	GO:0009175	5	1	18204	49	DPYD
1.339e-02	-4.31	regulation of modification of postsynaptic actin cytoskeleton	biological process	GO:1905274	5	1	18204	49	CYFIP1
1.339e-02	-4.31	pyrimidine deoxyribonucleoside metabolic process	biological process	GO:0046125	5	1	18204	49	DPYD
1.339e-02	-4.31	UMP catabolic process	biological process	GO:0046050	5	1	18204	49	DPYD
1.339e-02	-4.31	positive regulation of neurotrophin TRK receptor signaling pathway	biological process	GO:0051388	5	1	18204	49	CYFIP1
1.339e-02	-4.31	thrombopoietin-mediated signaling pathway	biological process	GO:0038163	5	1	18204	49	SH2B3
1.343e-02	-4.31	Lamp2-like_luminal	interpro domains	IPR048528	5	1	18521	50	CD68
1.343e-02	-4.31	4Fe4S_Fe-S-bd	interpro domains	IPR017896	5	1	18521	50	DPYD
1.343e-02	-4.31	Lysosome-assoc_membr_glycop	interpro domains	IPR002000	5	1	18521	50	CD68
1.343e-02	-4.31	Fringe-like_glycosylTrfase	interpro domains	IPR003378	5	1	18521	50	MFNG
1.343e-02	-4.31	DOCK_N	interpro domains	IPR032376	5	1	18521	50	DOCK2
1.343e-02	-4.31	HnRNP_R/Q_splicing_fac	interpro domains	IPR006535	5	1	18521	50	RBM47
1.343e-02	-4.31	DOCK_N_sub1	interpro domains	IPR042455	5	1	18521	50	DOCK2
1.347e-02	-4.31	ganglioside binding	molecular function	GO:0035594	5	1	18094	49	PSAP
1.347e-02	-4.31	phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity	molecular function	GO:0016314	5	1	18094	49	INPP5D
1.351e-02	-4.30	organophosphate catabolic process	biological process	GO:0046434	185	3	18204	49	DPYD,SMPD4,ENTPD1
1.355e-02	-4.30	negative regulation of immune system process	biological process	GO:0002683	529	5	18204	49	CD68,HCK,INPP5D,TNFAIP8L2,CD74
1.357e-02	-4.30	CNPY3 (canopy FGF signaling regulator 3)	protein interactions	10695	194	3	19454	50	HCK,CD74,VMP1
1.360e-02	-4.30	lamellipodium	cellular component	GO:0030027	203	3	19108	47	RAC2,CYFIP1,PLXND1
1.361e-02	-4.30	YIF1B (Yip1 interacting factor homolog B, membrane trafficking protein)	protein interactions	90522	69	2	19454	50	UNC93B1,P2RY6
1.361e-02	-4.30	EVL (Enah/Vasp-like)	protein interactions	51466	69	2	19454	50	HCK,FYB1
1.364e-02	-4.29	homotypic cell-cell adhesion	biological process	GO:0034109	66	2	18204	49	ENTPD1,PLEK
1.364e-02	-4.29	peptidyl-tyrosine phosphorylation	biological process	GO:0018108	66	2	18204	49	HCK,CSF1R
1.369e-02	-4.29	PH_19	pfam domains	PF19057	5	1	17795	49	ABR
1.369e-02	-4.29	Lamp	pfam domains	PF01299	5	1	17795	49	CD68
1.369e-02	-4.29	DOCK_N	pfam domains	PF16172	5	1	17795	49	DOCK2
1.369e-02	-4.29	Fringe	pfam domains	PF02434	5	1	17795	49	MFNG
1.370e-02	-4.29	EMD (emerin)	protein interactions	2010	771	6	19454	50	VMP1,SMPD4,P2RY6,RAC2,UNC93B1,RXRA
1.371e-02	-4.29	biological regulation	biological process	GO:0065007	12501	41	18204	49	THRB,MFNG,SNX17,RMC1,PLEK,ABR,PSAP,ITGB2,PREX1,RAC2,FYB1,SH2B3,MAP3K11,CSF1R,INPP5D,CMTM6,CYFIP1,RBM47,SPOCK3,PLXNC1,CD74,VMP1,P2RY6,GAB1,CSF3R,ZFP36L1,UNC93B1,ENTPD1,HCK,TNFAIP8L2,RASGRP2,ITM2B,CD68,MLKL,DAPP1,PLXND1,DOCK2,MARCO,ITGAX,RXRA,ELMO1
1.376e-02	-4.29	SGPL1 (sphingosine-1-phosphate lyase 1)	protein interactions	8879	195	3	19454	50	P2RY6,CD74,UNC93B1
1.380e-02	-4.28	Regulation of actin cytoskeleton	KEGG pathways	hsa04810	211	4	7161	32	ITGAX,ITGB2,RAC2,CYFIP1
1.380e-02	-4.28	Regulation of actin cytoskeleton	KEGG pathways	ko04810	211	4	7161	32	ITGB2,ITGAX,RAC2,CYFIP1
1.383e-02	-4.28	breast-carcinoma-lobular_carcinoma	COSMIC cancer mutations	breast-carcinoma-lobular_carcinoma	763	6	16828	44	RBM47,CSF1R,MLKL,MAP3K11,ZFP36L1,HCK
1.383e-02	-4.28	lobular_carcinoma	COSMIC cancer mutations	lobular_carcinoma	763	6	16828	44	CSF1R,MAP3K11,MLKL,HCK,RBM47,ZFP36L1
1.385e-02	-4.28	positive regulation of biological process	biological process	GO:0048518	6326	25	18204	49	PLEK,MFNG,THRB,MAP3K11,PREX1,ITGB2,RAC2,FYB1,CYFIP1,INPP5D,CSF1R,PLXNC1,RBM47,P2RY6,GAB1,ZFP36L1,CD74,VMP1,HCK,UNC93B1,DOCK2,PLXND1,RXRA,ITGAX,MARCO
1.386e-02	-4.28	cytosol	cellular component	GO:0005829	5475	21	19108	47	PREX1,DPYD,ZFP36L1,MLKL,HCK,CYFIP1,PLEK,FYB1,GAB1,ABR,SNX17,INPP5D,RXRA,ELMO1,SH2B3,MYO1F,RASGRP2,DOCK2,MAP3K11,DAPP1,RAC2
1.393e-02	-4.27	tertiary granule membrane	cellular component	GO:0070821	73	2	19108	47	ITGAX,ITGB2
1.399e-02	-4.27	IL6ST (interleukin 6 cytokine family signal transducer)	protein interactions	3572	70	2	19454	50	RAC2,HCK
1.400e-02	-4.27	organelle membrane	cellular component	GO:0031090	3742	16	19108	47	UNC93B1,MARCO,RAC2,SNX17,ITGAX,ITM2B,ITGB2,CSF3R,MFNG,CD68,SMPD4,CMTM6,RMC1,PSAP,CD74,VMP1
1.404e-02	-4.27	positive regulation of response to cytokine stimulus	biological process	GO:0060760	67	2	18204	49	CD74,RBM47
1.404e-02	-4.27	4FE4S_FER_1	prosite domains	PS00198	4	1	12186	43	DPYD
1.404e-02	-4.27	LAMP_3	prosite domains	PS51407	4	1	12186	43	CD68
1.406e-02	-4.26	innate immune response	biological process	GO:0045087	741	6	18204	49	UNC93B1,HCK,CSF1R,MARCO,TNFAIP8L2,CD74
1.406e-02	-4.26	cellular response to lipid	biological process	GO:0071396	534	5	18204	49	CD68,HCK,ZFP36L1,P2RY6,RXRA
1.409e-02	-4.26	pleura-mesothelioma	COSMIC cancer mutations	pleura-mesothelioma	4189	18	16828	44	ANKRD44,RASGRP2,HCK,DPYD,SNX17,CSF1R,ITGB2,ITGAX,PREX1,ADAM33,VMP1,THRB,CPN1,MLKL,MAP3K11,RAC2,MFNG,GAB1
1.410e-02	-4.26	intracellular receptor signaling pathway	biological process	GO:0030522	188	3	18204	49	UNC93B1,THRB,RXRA
1.427e-02	-4.25	RPN1 (ribophorin I)	protein interactions	6184	778	6	19454	50	SMPD4,VMP1,RAC2,RMC1,UNC93B1,P2RY6
1.433e-02	-4.25	NDC1 (NDC1 transmembrane nucleoporin)	protein interactions	55706	198	3	19454	50	RAC2,P2RY6,UNC93B1
1.436e-02	-4.24	Glycosphingolipid metabolism	REACTOME pathways	R-HSA-1660662	46	2	10285	41	PSAP,SMPD4
1.437e-02	-4.24	GALK1 (galactokinase 1)	protein interactions	2584	71	2	19454	50	RMC1,P2RY6
1.437e-02	-4.24	HIGD1A (HIG1 hypoxia inducible domain family member 1A)	protein interactions	25994	71	2	19454	50	P2RY6,UNC93B1
1.439e-02	-4.24	Angiopoietin Like Protein 8 Regulatory Pathway	WikiPathways	WP3915	132	3	5310	21	RXRA,THRB,MAP3K11
1.444e-02	-4.24	peptidyl-tyrosine modification	biological process	GO:0018212	68	2	18204	49	HCK,CSF1R
1.447e-02	-4.24	trunk	COSMIC cancer mutations	trunk	3554	16	16828	44	DOCK2,THRB,CSF3R,SMPD4,RBM47,PLEK,ANKRD44,MYO1F,HCK,DPYD,ITGB2,ITGAX,SPOCK3,ADAM33,TNFAIP8L2,ABR
1.460e-02	-4.23	renal_cell_carcinoma	COSMIC cancer mutations	renal_cell_carcinoma	4535	19	16828	44	CSF1R,SNX17,DPYD,RASGRP2,HCK,ANKRD44,ADAM33,PREX1,ITGAX,ITGB2,MLKL,MAP3K11,THRB,CPN1,DOCK2,VMP1,GAB1,MFNG,RAC2
1.460e-02	-4.23	kidney-carcinoma-renal_cell_carcinoma	COSMIC cancer mutations	kidney-carcinoma-renal_cell_carcinoma	4535	19	16828	44	MLKL,MAP3K11,CPN1,THRB,DOCK2,VMP1,RAC2,GAB1,MFNG,RASGRP2,HCK,DPYD,CSF1R,SNX17,ANKRD44,PREX1,ADAM33,ITGAX,ITGB2
1.467e-02	-4.22	mRNA editing complex	cellular component	GO:0045293	6	1	19108	47	RBM47
1.470e-02	-4.22	regulation of cellular component size	biological process	GO:0032535	352	4	18204	49	HCK,PREX1,CYFIP1,PLEK
1.471e-02	-4.22	negative regulation of leukocyte activation	biological process	GO:0002695	191	3	18204	49	INPP5D,TNFAIP8L2,CD74
1.476e-02	-4.22	FAM234B (family with sequence similarity 234 member B)	protein interactions	57613	72	2	19454	50	ITM2B,RAC2
1.476e-02	-4.22	ITGB2 (integrin subunit beta 2)	protein interactions	3689	72	2	19454	50	ITGAX,ITGB2
1.476e-02	-4.22	PPARGC1A (PPARG coactivator 1 alpha)	protein interactions	10891	72	2	19454	50	THRB,RXRA
1.476e-02	-4.22	JMJD1C (jumonji domain containing 1C)	protein interactions	221037	72	2	19454	50	RXRA,THRB
1.511e-02	-4.19	Dedicator of cytokinesis N-terminal subdomain	gene3d domains	1.20.1270.350	5	1	14470	44	DOCK2
1.512e-02	-4.19	positive regulation of hemopoiesis	biological process	GO:1903708	193	3	18204	49	ZFP36L1,CD74,INPP5D
1.512e-02	-4.19	positive regulation of leukocyte differentiation	biological process	GO:1902107	193	3	18204	49	INPP5D,ZFP36L1,CD74
1.515e-02	-4.19	PANK4 (pantothenate kinase 4 (inactive))	protein interactions	55229	73	2	19454	50	UNC93B1,RMC1
1.515e-02	-4.19	TLR9 (toll like receptor 9)	protein interactions	54106	73	2	19454	50	INPP5D,UNC93B1
1.515e-02	-4.19	DAB2IP (DAB2 interacting protein)	protein interactions	153090	73	2	19454	50	RAC2,SNX17
1.526e-02	-4.18	antigen processing and presentation of peptide antigen	biological process	GO:0048002	70	2	18204	49	CD74,UNC93B1
1.530e-02	-4.18	CKAP4 (cytoskeleton associated protein 4)	protein interactions	10970	571	5	19454	50	RAC2,SMPD4,P2RY6,VMP1,UNC93B1
1.531e-02	-4.18	CERS2 (ceramide synthase 2)	protein interactions	29956	203	3	19454	50	UNC93B1,P2RY6,RAC2
1.532e-02	-4.18	SLC35E2A (solute carrier family 35 member E2A (pseudogene))	protein interactions	9906	6	1	19454	50	ADAM33
1.532e-02	-4.18	Ncoa2 (nuclear receptor coactivator 2)	protein interactions	17978	6	1	19454	50	RXRA
1.532e-02	-4.18	ITGAX (integrin subunit alpha X)	protein interactions	3687	6	1	19454	50	ITGB2
1.532e-02	-4.18	CD300LF (CD300 molecule like family member f)	protein interactions	146722	6	1	19454	50	INPP5D
1.532e-02	-4.18	Bace1 (beta-site APP cleaving enzyme 1)	protein interactions	23821	6	1	19454	50	PSAP
1.533e-02	-4.18	regulation of response to cytokine stimulus	biological process	GO:0060759	194	3	18204	49	SH2B3,CD74,RBM47
1.535e-02	-4.18	DH-domain	interpro domains	IPR000219	70	2	18521	50	PREX1,ABR
1.541e-02	-4.17	secretory vesicle	cellular component	GO:0099503	1076	7	19108	47	ITGAX,CYFIP1,PSAP,CD68,CMTM6,ITGB2,DOCK2
1.552e-02	-4.17	INPPL1 (inositol polyphosphate phosphatase like 1)	protein interactions	3636	204	3	19454	50	CSF1R,INPP5D,GAB1
1.552e-02	-4.17	VAV1 (vav guanine nucleotide exchange factor 1)	protein interactions	7409	204	3	19454	50	GAB1,DOCK2,HCK
1.554e-02	-4.16	haematopoietic_neoplasm	COSMIC cancer mutations	haematopoietic_neoplasm	11082	36	16828	44	ITGAX,SH2B3,ELMO1,ADAM33,ENTPD1,ANKRD44,P2RY6,PLXND1,SNX17,MYO1F,DPYD,HCK,CD74,MARCO,CD68,MAP3K11,MLKL,CPN1,SLCO2B1,SPOCK3,RXRA,PREX1,CMTM6,PSAP,DAPP1,CSF1R,PLXNC1,GAB1,SMPD4,RAC2,PLEK,DOCK2,VMP1,NCAM2,THRB,CSF3R
1.554e-02	-4.16	COG1 (component of oligomeric golgi complex 1)	protein interactions	9382	74	2	19454	50	P2RY6,UNC93B1
1.554e-02	-4.16	KCNK1 (potassium two pore domain channel subfamily K member 1)	protein interactions	3775	74	2	19454	50	CMTM6,UNC93B1
1.554e-02	-4.16	TEC (tec protein tyrosine kinase)	protein interactions	7006	74	2	19454	50	GAB1,CYFIP1
1.554e-02	-4.16	CACNA2D1 (calcium voltage-gated channel auxiliary subunit alpha2delta 1)	protein interactions	781	74	2	19454	50	VMP1,ITM2B
1.554e-02	-4.16	COG7 (component of oligomeric golgi complex 7)	protein interactions	91949	74	2	19454	50	P2RY6,UNC93B1
1.565e-02	-4.16	STROIDFINGER	prints domains	PR00047	46	2	5227	22	RXRA,THRB
1.567e-02	-4.16	IL-3 Signaling Pathway	WikiPathways	WP286	49	2	5310	21	INPP5D,HCK
1.576e-02	-4.15	DBL_dom_sf	interpro domains	IPR035899	71	2	18521	50	PREX1,ABR
1.592e-02	-4.14	CDKAL1 (CDK5 regulatory subunit associated protein 1 like 1)	protein interactions	54901	206	3	19454	50	UNC93B1,RAC2,P2RY6
1.592e-02	-4.14	RhoGEF	pfam domains	PF00621	70	2	17795	49	ABR,PREX1
1.594e-02	-4.14	CHP1 (calcineurin like EF-hand protein 1)	protein interactions	11261	75	2	19454	50	P2RY6,UNC93B1
1.594e-02	-4.14	SPTLC2 (serine palmitoyltransferase long chain base subunit 2)	protein interactions	9517	75	2	19454	50	UNC93B1,P2RY6
1.599e-02	-4.14	positive regulation of cell projection organization	biological process	GO:0031346	361	4	18204	49	RAC2,CYFIP1,PLXNC1,PLXND1
1.604e-02	-4.13	positive regulation of prostaglandin biosynthetic process	biological process	GO:0031394	6	1	18204	49	CD74
1.604e-02	-4.13	regulation of translation at synapse, modulating synaptic transmission	biological process	GO:0099547	6	1	18204	49	CYFIP1
1.604e-02	-4.13	dCMP metabolic process	biological process	GO:0046063	6	1	18204	49	DPYD
1.604e-02	-4.13	positive regulation of macrophage proliferation	biological process	GO:0120041	6	1	18204	49	CSF1R
1.604e-02	-4.13	regulation of synapse pruning	biological process	GO:1905806	6	1	18204	49	PLXNC1
1.604e-02	-4.13	enucleate erythrocyte development	biological process	GO:0048822	6	1	18204	49	RAC2
1.604e-02	-4.13	membrane raft distribution	biological process	GO:0031580	6	1	18204	49	DOCK2
1.604e-02	-4.13	regulation of translation at postsynapse	biological process	GO:0140245	6	1	18204	49	CYFIP1
1.604e-02	-4.13	dUMP catabolic process	biological process	GO:0046079	6	1	18204	49	DPYD
1.604e-02	-4.13	positive regulation of vitamin D receptor signaling pathway	biological process	GO:0070564	6	1	18204	49	RXRA
1.604e-02	-4.13	negative regulation of amine metabolic process	biological process	GO:0033239	6	1	18204	49	ITGB2
1.604e-02	-4.13	regulation of endothelial tube morphogenesis	biological process	GO:1901509	6	1	18204	49	ITGAX
1.604e-02	-4.13	deoxyribonucleoside catabolic process	biological process	GO:0046121	6	1	18204	49	DPYD
1.604e-02	-4.13	dCMP catabolic process	biological process	GO:0006249	6	1	18204	49	DPYD
1.604e-02	-4.13	sphingomyelin catabolic process	biological process	GO:0006685	6	1	18204	49	SMPD4
1.607e-02	-4.13	Host Interactions of HIV factors	REACTOME pathways	R-HSA-162909	134	3	10285	41	ELMO1,HCK,DOCK2
1.608e-02	-4.13	external side of plasma membrane	cellular component	GO:0009897	396	4	19108	47	ITGAX,CSF3R,ITGB2,CD74
1.609e-02	-4.13	ELMO_dom	interpro domains	IPR006816	6	1	18521	50	ELMO1
1.609e-02	-4.13	Integrin_bsu_cyt_dom	interpro domains	IPR014836	6	1	18521	50	ITGB2
1.609e-02	-4.13	Saposin-like	interpro domains	IPR011001	6	1	18521	50	PSAP
1.609e-02	-4.13	positive regulation of chemokine production	biological process	GO:0032722	72	2	18204	49	CSF1R,CD74
1.613e-02	-4.13	OPALIN (oligodendrocytic myelin paranodal and inner loop protein)	protein interactions	93377	207	3	19454	50	SMPD4,UNC93B1,CMTM6
1.614e-02	-4.13	thyroid hormone binding	molecular function	GO:0070324	6	1	18094	49	THRB
1.614e-02	-4.13	CTPase activity	molecular function	GO:0043273	6	1	18094	49	ENTPD1
1.614e-02	-4.13	retinoic acid-responsive element binding	molecular function	GO:0044323	6	1	18094	49	RXRA
1.614e-02	-4.13	ADP phosphatase activity	molecular function	GO:0043262	6	1	18094	49	ENTPD1
1.614e-02	-4.13	inositol-1,3,4,5-tetrakisphosphate 5-phosphatase activity	molecular function	GO:0052659	6	1	18094	49	INPP5D
1.624e-02	-4.12	vesicle	cellular component	GO:0031982	4141	17	19108	47	SNX17,ITM2B,ITGAX,UNC93B1,DOCK2,MARCO,RAC2,RMC1,CD74,PSAP,HCK,CYFIP1,CSF3R,ITGB2,CD68,CMTM6,ENTPD1
1.630e-02	-4.12	STRDHORMONER	prints domains	PR00398	47	2	5227	22	RXRA,THRB
1.633e-02	-4.11	PAK2 (p21 (RAC1) activated kinase 2)	protein interactions	5062	208	3	19454	50	HCK,DOCK2,RAC2
1.635e-02	-4.11	PGM3 (phosphoglucomutase 3)	protein interactions	5238	76	2	19454	50	P2RY6,SNX17
1.635e-02	-4.11	CD1B (CD1b molecule)	protein interactions	910	76	2	19454	50	PSAP,ITM2B
1.641e-02	-4.11	ELMO_CED12	pfam domains	PF04727	6	1	17795	49	ELMO1
1.641e-02	-4.11	Integrin_B_tail	pfam domains	PF07965	6	1	17795	49	ITGB2
1.641e-02	-4.11	Integrin_b_cyt	pfam domains	PF08725	6	1	17795	49	ITGB2
1.652e-02	-4.10	endothelial cell migration	biological process	GO:0043542	73	2	18204	49	PLXND1,GAB1
1.654e-02	-4.10	ATP1B3 (ATPase Na+/K+ transporting subunit beta 3)	protein interactions	483	209	3	19454	50	RAC2,P2RY6,UNC93B1
1.656e-02	-4.10	superpathway of pyrimidine ribonucleosides degradation	BIOCYC pathways	META_PWY-7209	5	1	902	3	DPYD
1.660e-02	-4.10	ERBB2 (erb-b2 receptor tyrosine kinase 2)	protein interactions	2064	583	5	19454	50	HCK,SH2B3,SMPD4,GAB1,PSAP
1.671e-02	-4.09	cargo receptor activity	molecular function	GO:0038024	73	2	18094	49	MARCO,ITGB2
1.673e-02	-4.09	RETINOIDXR	prints domains	PR00545	4	1	5227	22	RXRA
1.673e-02	-4.09	THYROIDHORMR	prints domains	PR00546	4	1	5227	22	THRB
1.673e-02	-4.09	LYSASSOCTDMP	prints domains	PR00336	4	1	5227	22	CD68
1.676e-02	-4.09	TNS3 (tensin 3)	protein interactions	64759	77	2	19454	50	RAC2,GAB1
1.676e-02	-4.09	ADGRL2 (adhesion G protein-coupled receptor L2)	protein interactions	23266	77	2	19454	50	UNC93B1,RAC2
1.676e-02	-4.09	PALD1 (phosphatase domain containing paladin 1)	protein interactions	27143	77	2	19454	50	RAC2,P2RY6
1.676e-02	-4.09	DYM (dymeclin)	protein interactions	54808	77	2	19454	50	P2RY6,UNC93B1
1.680e-02	-4.09	astrocytoma_Grade_III	COSMIC cancer mutations	astrocytoma_Grade_III	1544	9	16828	44	ELMO1,PLEK,SMPD4,RAC2,CD74,DPYD,PLXNC1,NCAM2,DOCK2
1.684e-02	-4.08	leukocyte activation involved in immune response	biological process	GO:0002366	201	3	18204	49	MFNG,DOCK2,CD74
1.695e-02	-4.08	organelle localization by membrane tethering	biological process	GO:0140056	74	2	18204	49	PLEK,VMP1
1.696e-02	-4.08	EPHB2 (EPH receptor B2)	protein interactions	2048	211	3	19454	50	GAB1,CYFIP1,CSF1R
1.703e-02	-4.07	immune response-regulating signaling pathway	biological process	GO:0002764	368	4	18204	49	UNC93B1,HCK,INPP5D,FYB1
1.703e-02	-4.07	activation of immune response	biological process	GO:0002253	368	4	18204	49	FYB1,INPP5D,HCK,UNC93B1
1.705e-02	-4.07	cell junction	cellular component	GO:0030054	2224	11	19108	47	GAB1,RAC2,FYB1,ITGB2,RASGRP2,PLXNC1,HCK,CYFIP1,PLXND1,MLKL,ABR
1.706e-02	-4.07	regulation of protein polymerization	biological process	GO:0032271	202	3	18204	49	PREX1,CYFIP1,HCK
1.708e-02	-4.07	regulation of localization	biological process	GO:0032879	2028	11	18204	49	RXRA,CYFIP1,DOCK2,HCK,ITGB2,RAC2,P2RY6,ZFP36L1,CD74,VMP1,SNX17
1.709e-02	-4.07	human chr12q24.12	chromosome location	human chr12q24.12	9	1	26134	50	SH2B3
1.709e-02	-4.07	cerebellar climbing fiber to Purkinje cell synapse	cellular component	GO:0150053	7	1	19108	47	PLXNC1
1.717e-02	-4.06	cytoplasm	cellular component	GO:0005737	12081	37	19108	47	FYB1,CSF3R,ITGB2,PLEK,MFNG,CD68,SMPD4,CMTM6,RMC1,ZFP36L1,PSAP,PREX1,HCK,MLKL,VMP1,RASGRP2,MARCO,RXRA,RBM47,ITGAX,GAB1,DPYD,TNFAIP8L2,CD74,CYFIP1,UNC93B1,MAP3K11,DAPP1,MYO1F,DOCK2,SH2B3,RAC2,INPP5D,ABR,SNX17,ELMO1,ITM2B
1.728e-02	-4.06	negative regulation of cell-cell adhesion	biological process	GO:0022408	203	3	18204	49	TNFAIP8L2,CD74,SH2B3
1.737e-02	-4.05	Ras signaling pathway	KEGG pathways	hsa04014	226	4	7161	32	CSF1R,GAB1,RASGRP2,RAC2
1.738e-02	-4.05	adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway	biological process	GO:0007193	75	2	18204	49	PSAP,MARCO
1.738e-02	-4.05	regulation of calcium ion transmembrane transporter activity	biological process	GO:1901019	75	2	18204	49	P2RY6,VMP1
1.739e-02	-4.05	LMNB1 (lamin B1)	protein interactions	4001	590	5	19454	50	VMP1,SMPD4,RAC2,MYO1F,RXRA
1.739e-02	-4.05	PPP6C (protein phosphatase 6 catalytic subunit)	protein interactions	5537	213	3	19454	50	UNC93B1,ANKRD44,P2RY6
1.748e-02	-4.05	Nuclear Receptor transcription pathway	REACTOME pathways	R-HSA-383280	51	2	10285	41	RXRA,THRB
1.752e-02	-4.04	4FE4S_FER_2	prosite domains	PS51379	5	1	12186	43	DPYD
1.759e-02	-4.04	CANT1 (calcium activated nucleotidase 1)	protein interactions	124583	79	2	19454	50	MFNG,ITM2B
1.759e-02	-4.04	ATAD1 (ATPase family AAA domain containing 1)	protein interactions	84896	79	2	19454	50	UNC93B1,RAC2
1.759e-02	-4.04	papillary_renal_cell_carcinoma	COSMIC cancer mutations	papillary_renal_cell_carcinoma	6364	24	16828	44	RBM47,ITM2B,RAC2,SMPD4,SLCO2B1,MLKL,MAP3K11,NCAM2,DOCK2,PREX1,ELMO1,ABR,SPOCK3,ITGB2,SH2B3,ITGAX,HCK,DPYD,CSF1R,MYO1F,PLXND1,DAPP1,P2RY6,ANKRD44
1.759e-02	-4.04	kidney-carcinoma-papillary_renal_cell_carcinoma	COSMIC cancer mutations	kidney-carcinoma-papillary_renal_cell_carcinoma	6364	24	16828	44	ITM2B,SLCO2B1,MLKL,MAP3K11,ELMO1,SH2B3,ITGAX,DPYD,HCK,PLXND1,MYO1F,P2RY6,ANKRD44,RBM47,RAC2,SMPD4,NCAM2,DOCK2,PREX1,ABR,SPOCK3,ITGB2,DAPP1,CSF1R
1.761e-02	-4.04	CA9 (carbonic anhydrase 9)	protein interactions	768	214	3	19454	50	VMP1,SMPD4,ITM2B
1.761e-02	-4.04	NCK1 (NCK adaptor protein 1)	protein interactions	4690	214	3	19454	50	GAB1,CYFIP1,INPP5D
1.761e-02	-4.04	NCAPD2 (non-SMC condensin I complex subunit D2)	protein interactions	9918	214	3	19454	50	UNC93B1,CD74,P2RY6
1.774e-02	-4.03	cell activation involved in immune response	biological process	GO:0002263	205	3	18204	49	MFNG,CD74,DOCK2
1.776e-02	-4.03	caveola	cellular component	GO:0005901	83	2	19108	47	ENTPD1,HCK
1.786e-02	-4.03	TLR8 (toll like receptor 8)	protein interactions	51311	7	1	19454	50	UNC93B1
1.786e-02	-4.03	ZCCHC24 (zinc finger CCHC-type containing 24)	protein interactions	219654	7	1	19454	50	RBM47
1.786e-02	-4.03	Gadd45b (growth arrest and DNA-damage-inducible 45 beta)	protein interactions	17873	7	1	19454	50	RXRA
1.804e-02	-4.01	ATP2B1 (ATPase plasma membrane Ca2+ transporting 1)	protein interactions	490	216	3	19454	50	UNC93B1,RAC2,P2RY6
1.804e-02	-4.01	HACD3 (3-hydroxyacyl-CoA dehydratase 3)	protein interactions	51495	216	3	19454	50	UNC93B1,RAC2,P2RY6
1.811e-02	-4.01	-	gene3d domains	2.40.160.110	6	1	14470	44	CD68
1.818e-02	-4.01	kinase binding	molecular function	GO:0019900	780	6	18094	49	SH2B3,PLEK,ITGB2,MLKL,MAP3K11,ITGAX
1.824e-02	-4.00	transmembrane signaling receptor activity	molecular function	GO:0004888	1251	8	18094	49	PLXND1,ITGB2,CSF3R,CSF1R,PLXNC1,CD74,MARCO,P2RY6
1.827e-02	-4.00	endocytic recycling	biological process	GO:0032456	77	2	18204	49	CMTM6,SNX17
1.829e-02	-4.00	cellular process	biological process	GO:0009987	14996	46	18204	49	VMP1,ZFP36L1,GAB1,P2RY6,RASGRP2,ENTPD1,DOCK2,CD68,LRMDA,MLKL,PLXND1,ELMO1,RXRA,SLCO2B1,MFNG,FYB1,PREX1,MYO1F,CMTM6,SMPD4,CPN1,NCAM2,RBM47,CD74,CSF3R,HCK,UNC93B1,TNFAIP8L2,DPYD,DAPP1,MARCO,ITGAX,SNX17,ABR,PLEK,RMC1,THRB,RAC2,ITGB2,MAP3K11,SH2B3,PSAP,CYFIP1,CSF1R,INPP5D,PLXNC1
1.840e-02	-4.00	regulation of leukocyte activation	biological process	GO:0002694	572	5	18204	49	ZFP36L1,CD74,RAC2,INPP5D,TNFAIP8L2
1.843e-02	-3.99	KRTAP3-3 (keratin associated protein 3-3)	protein interactions	85293	81	2	19454	50	P2RY6,DOCK2
1.843e-02	-3.99	FADS1 (fatty acid desaturase 1)	protein interactions	3992	81	2	19454	50	VMP1,RAC2
1.843e-02	-3.99	THRB (thyroid hormone receptor beta)	protein interactions	7068	81	2	19454	50	THRB,RXRA
1.843e-02	-3.99	CAND2 (cullin associated and neddylation dissociated 2 (putative))	protein interactions	23066	81	2	19454	50	P2RY6,UNC93B1
1.849e-02	-3.99	KRTAP1-1 (keratin associated protein 1-1)	protein interactions	81851	218	3	19454	50	DOCK2,P2RY6,HCK
1.866e-02	-3.98	regulation of chemotaxis	biological process	GO:0050920	209	3	18204	49	RAC2,CD74,CSF1R
1.869e-02	-3.98	response to interleukin-3	biological process	GO:0036015	7	1	18204	49	SH2B3
1.869e-02	-3.98	membrane raft localization	biological process	GO:0051665	7	1	18204	49	DOCK2
1.869e-02	-3.98	dUMP metabolic process	biological process	GO:0046078	7	1	18204	49	DPYD
1.869e-02	-3.98	macropinocytosis	biological process	GO:0044351	7	1	18204	49	DOCK2
1.869e-02	-3.98	bradykinin catabolic process	biological process	GO:0010815	7	1	18204	49	CPN1
1.869e-02	-3.98	positive regulation of isomerase activity	biological process	GO:0010912	7	1	18204	49	ITGB2
1.869e-02	-3.98	autophagosome membrane docking	biological process	GO:0016240	7	1	18204	49	VMP1
1.869e-02	-3.98	cellular response to interleukin-3	biological process	GO:0036016	7	1	18204	49	SH2B3
1.869e-02	-3.98	regulation of macrophage proliferation	biological process	GO:0120040	7	1	18204	49	CSF1R
1.869e-02	-3.98	mitochondrion-endoplasmic reticulum membrane tethering	biological process	GO:1990456	7	1	18204	49	VMP1
1.869e-02	-3.98	chorio-allantoic fusion	biological process	GO:0060710	7	1	18204	49	ZFP36L1
1.869e-02	-3.98	regulation of ATPase-coupled calcium transmembrane transporter activity	biological process	GO:1901894	7	1	18204	49	VMP1
1.869e-02	-3.98	retinal cell apoptotic process	biological process	GO:1990009	7	1	18204	49	THRB
1.869e-02	-3.98	positive regulation of dendritic cell antigen processing and presentation	biological process	GO:0002606	7	1	18204	49	CD74
1.869e-02	-3.98	platelet degranulation	biological process	GO:0002576	7	1	18204	49	PLEK
1.869e-02	-3.98	nuclear-transcribed mRNA catabolic process, deadenylation-independent decay	biological process	GO:0031086	7	1	18204	49	ZFP36L1
1.869e-02	-3.98	regulation of isomerase activity	biological process	GO:0010911	7	1	18204	49	ITGB2
1.869e-02	-3.98	regulation of mast cell proliferation	biological process	GO:0070666	7	1	18204	49	RAC2
1.874e-02	-3.98	Rho GTPase cycle	REACTOME pathways	R-HSA-194840	142	3	10285	41	RAC2,PREX1,ABR
1.875e-02	-3.98	SaposinB_dom	interpro domains	IPR008139	7	1	18521	50	PSAP
1.875e-02	-3.98	Integrin_bsu_tail_dom_sf	interpro domains	IPR036349	7	1	18521	50	ITGB2
1.875e-02	-3.98	Hematopoietin_rcpt_Gp130_CS	interpro domains	IPR003529	7	1	18521	50	CSF3R
1.875e-02	-3.98	SPARC/Testican_Ca-bd-dom	interpro domains	IPR019577	7	1	18521	50	SPOCK3
1.875e-02	-3.98	Integrin_bsu_tail	interpro domains	IPR012896	7	1	18521	50	ITGB2
1.875e-02	-3.98	MYSc_Myo1	interpro domains	IPR036072	7	1	18521	50	MYO1F
1.881e-02	-3.97	inositol-1,4,5-trisphosphate 5-phosphatase activity	molecular function	GO:0052658	7	1	18094	49	INPP5D
1.881e-02	-3.97	LBD domain binding	molecular function	GO:0050693	7	1	18094	49	RXRA
1.881e-02	-3.97	inositol-polyphosphate 5-phosphatase activity	molecular function	GO:0004445	7	1	18094	49	INPP5D
1.881e-02	-3.97	phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity	molecular function	GO:0034485	7	1	18094	49	INPP5D
1.881e-02	-3.97	sphingomyelin phosphodiesterase activity	molecular function	GO:0004767	7	1	18094	49	SMPD4
1.881e-02	-3.97	MHC class II protein binding	molecular function	GO:0042289	7	1	18094	49	CD74
1.893e-02	-3.97	SCFD1 (sec1 family domain containing 1)	protein interactions	23256	220	3	19454	50	UNC93B1,RAC2,P2RY6
1.912e-02	-3.96	SPARC_Ca_bdg	pfam domains	PF10591	7	1	17795	49	SPOCK3
1.912e-02	-3.96	KRTAP10-8 (keratin associated protein 10-8)	protein interactions	386681	399	4	19454	50	HCK,ITGB2,P2RY6,DOCK2
1.913e-02	-3.96	positive regulation of GTPase activity	biological process	GO:0043547	211	3	18204	49	RASGRP2,PREX1,ABR
1.917e-02	-3.95	myeloid cell development	biological process	GO:0061515	79	2	18204	49	RAC2,SH2B3
1.917e-02	-3.95	regulation of protein targeting	biological process	GO:1903533	79	2	18204	49	ITGB2,RAC2
1.932e-02	-3.95	positive regulation of cell communication	biological process	GO:0010647	1792	10	18204	49	RXRA,MAP3K11,RBM47,MARCO,CD74,CYFIP1,P2RY6,CSF1R,THRB,MFNG
1.939e-02	-3.94	PDGFRB (platelet derived growth factor receptor beta)	protein interactions	5159	222	3	19454	50	RAC2,GAB1,CSF1R
1.946e-02	-3.94	positive regulation of signaling	biological process	GO:0023056	1794	10	18204	49	RXRA,MAP3K11,MARCO,RBM47,CD74,P2RY6,CYFIP1,CSF1R,MFNG,THRB
1.952e-02	-3.94	regulation of signaling	biological process	GO:0023051	3534	16	18204	49	INPP5D,CSF1R,CYFIP1,DOCK2,RBM47,MARCO,RXRA,MFNG,THRB,P2RY6,PLEK,ABR,CD74,SH2B3,MAP3K11,PREX1
1.966e-02	-3.93	Dbl homology (DH) domain	gene3d domains	1.20.900.10	71	2	14470	44	PREX1,ABR
1.974e-02	-3.93	KRTAP3-1 (keratin associated protein 3-1)	protein interactions	83896	84	2	19454	50	DOCK2,HCK
1.974e-02	-3.93	Tyr_kinase_cat_dom	interpro domains	IPR020635	80	2	18521	50	HCK,CSF1R
1.978e-02	-3.92	MET activates PTPN11	REACTOME pathways	R-HSA-8865999	5	1	10285	41	GAB1
1.984e-02	-3.92	EPO signaling pathway	Pathway Interaction DB	epopathway	33	2	2226	15	SH2B3,GAB1
1.985e-02	-3.92	pyrimidine ribonucleosides degradation	BIOCYC pathways	HUMAN_PWY-7209	6	1	902	3	DPYD
1.985e-02	-3.92	MFSD4A (major facilitator superfamily domain containing 4A)	protein interactions	148808	224	3	19454	50	UNC93B1,VMP1,SMPD4
1.987e-02	-3.92	regulation of cell communication	biological process	GO:0010646	3541	16	18204	49	CD74,P2RY6,ABR,PLEK,THRB,MFNG,PREX1,SH2B3,MAP3K11,DOCK2,CYFIP1,CSF1R,INPP5D,RXRA,RBM47,MARCO
2.008e-02	-3.91	RINT1 (RAD50 interactor 1)	protein interactions	60561	225	3	19454	50	UNC93B1,RAC2,P2RY6
2.018e-02	-3.90	ATP5ME (ATP synthase membrane subunit e)	protein interactions	521	85	2	19454	50	P2RY6,UNC93B1
2.026e-02	-3.90	regulation of supramolecular fiber organization	biological process	GO:1902903	388	4	18204	49	PREX1,PLEK,CYFIP1,HCK
2.028e-02	-3.90	biological process involved in interspecies interaction between organisms	biological process	GO:0044419	1540	9	18204	49	CD74,CD68,CSF1R,MLKL,UNC93B1,HCK,MARCO,TNFAIP8L2,ITGAX
2.032e-02	-3.90	AUP1 (AUP1 lipid droplet regulating VLDL assembly factor)	protein interactions	550	226	3	19454	50	P2RY6,RAC2,UNC93B1
2.034e-02	-3.90	regulation of lymphocyte differentiation	biological process	GO:0045619	216	3	18204	49	INPP5D,ZFP36L1,CD74
2.038e-02	-3.89	CHURC1-FNTB (CHURC1-FNTB readthrough)	protein interactions	100529261	8	1	19454	50	CYFIP1
2.038e-02	-3.89	CD1D (CD1d molecule)	protein interactions	912	8	1	19454	50	CD74
2.038e-02	-3.89	DISP3 (dispatched RND transporter family member 3)	protein interactions	57540	8	1	19454	50	RASGRP2
2.049e-02	-3.89	human chr11q13.1	chromosome location	human chr11q13.1	115	2	26134	50	MAP3K11,RASGRP2
2.056e-02	-3.88	endoderm development	biological process	GO:0007492	82	2	18204	49	ZFP36L1,ITGB2
2.057e-02	-3.88	ESYT1 (extended synaptotagmin 1)	protein interactions	23344	408	4	19454	50	RAC2,VMP1,SMPD4,P2RY6
2.057e-02	-3.88	arm	COSMIC cancer mutations	arm	1331	8	16828	44	ENTPD1,DPYD,RASGRP2,MYO1F,CSF1R,MLKL,MARCO,ADAM33
2.059e-02	-3.88	focal adhesion	cellular component	GO:0005925	427	4	19108	47	ITGB2,RAC2,CYFIP1,HCK
2.063e-02	-3.88	HIBADH (3-hydroxyisobutyrate dehydrogenase)	protein interactions	11112	86	2	19454	50	ADAM33,DAPP1
2.063e-02	-3.88	WAS (WASP actin nucleation promoting factor)	protein interactions	7454	86	2	19454	50	FYB1,HCK
2.073e-02	-3.88	haematopoietic_and_lymphoid_tissue-other-normal	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue-other-normal	8	1	16828	44	CSF1R
2.079e-02	-3.87	TNPO3 (transportin 3)	protein interactions	23534	228	3	19454	50	UNC93B1,MFNG,P2RY6
2.079e-02	-3.87	receptor tyrosine kinase binding	molecular function	GO:0030971	82	2	18094	49	SH2B3,ITGAX
2.079e-02	-3.87	multicellular organismal process	biological process	GO:0032501	6177	24	18204	49	THRB,MFNG,ZFP36L1,PLEK,GAB1,SNX17,VMP1,CD74,TNFAIP8L2,PSAP,ENTPD1,ITM2B,SH2B3,RAC2,PREX1,ITGB2,PLXND1,INPP5D,CSF1R,CYFIP1,DOCK2,SLCO2B1,MARCO,NCAM2
2.082e-02	-3.87	SapB	smart domains	SM00741	6	1	9717	34	PSAP
2.082e-02	-3.87	Integrin_b_cyt	smart domains	SM01241	6	1	9717	34	ITGB2
2.088e-02	-3.87	ADXRDTASE	prints domains	PR00419	5	1	5227	22	DPYD
2.099e-02	-3.86	ELMO	prosite domains	PS51335	6	1	12186	43	ELMO1
2.103e-02	-3.86	positive regulation of ion transmembrane transporter activity	biological process	GO:0032414	83	2	18204	49	VMP1,P2RY6
2.103e-02	-3.86	positive regulation of B cell activation	biological process	GO:0050871	83	2	18204	49	CD74,INPP5D
2.103e-02	-3.86	positive regulation of calcium ion transmembrane transport	biological process	GO:1904427	83	2	18204	49	P2RY6,VMP1
2.108e-02	-3.86	FGR (FGR proto-oncogene, Src family tyrosine kinase)	protein interactions	2268	87	2	19454	50	HCK,INPP5D
2.111e-02	-3.86	specific granule membrane	cellular component	GO:0035579	91	2	19108	47	ITGB2,CMTM6
2.121e-02	-3.85	axon	cellular component	GO:0030424	650	5	19108	47	NCAM2,CYFIP1,PLXND1,PREX1,ABR
2.122e-02	-3.85	macromolecule localization	biological process	GO:0033036	2376	12	18204	49	SLCO2B1,CMTM6,CD68,FYB1,ITGB2,UNC93B1,PSAP,VMP1,SNX17,CD74,PLEK,ZFP36L1
2.134e-02	-3.85	female mating behavior	biological process	GO:0060180	8	1	18204	49	THRB
2.134e-02	-3.85	CMP metabolic process	biological process	GO:0046035	8	1	18204	49	DPYD
2.134e-02	-3.85	negative regulation of monocyte differentiation	biological process	GO:0045656	8	1	18204	49	INPP5D
2.134e-02	-3.85	regulation of keratinocyte apoptotic process	biological process	GO:1902172	8	1	18204	49	ZFP36L1
2.134e-02	-3.85	necroptotic signaling pathway	biological process	GO:0097527	8	1	18204	49	MLKL
2.134e-02	-3.85	glycolipid transport	biological process	GO:0046836	8	1	18204	49	PSAP
2.134e-02	-3.85	regulation of mast cell chemotaxis	biological process	GO:0060753	8	1	18204	49	RAC2
2.134e-02	-3.85	pyrimidine nucleobase catabolic process	biological process	GO:0006208	8	1	18204	49	DPYD
2.134e-02	-3.85	regulation of female receptivity	biological process	GO:0045924	8	1	18204	49	THRB
2.134e-02	-3.85	dichotomous subdivision of an epithelial terminal unit	biological process	GO:0060600	8	1	18204	49	PLXND1
2.134e-02	-3.85	cellular response to macrophage colony-stimulating factor stimulus	biological process	GO:0036006	8	1	18204	49	CSF1R
2.134e-02	-3.85	positive regulation of Arp2/3 complex-mediated actin nucleation	biological process	GO:2000601	8	1	18204	49	CYFIP1
2.134e-02	-3.85	negative regulation of erythrocyte differentiation	biological process	GO:0045647	8	1	18204	49	ZFP36L1
2.134e-02	-3.85	negative regulation of granulocyte differentiation	biological process	GO:0030853	8	1	18204	49	INPP5D
2.134e-02	-3.85	pyrimidine nucleoside monophosphate catabolic process	biological process	GO:0009131	8	1	18204	49	DPYD
2.134e-02	-3.85	pyrimidine ribonucleotide catabolic process	biological process	GO:0009222	8	1	18204	49	DPYD
2.134e-02	-3.85	type I pneumocyte differentiation	biological process	GO:0060509	8	1	18204	49	THRB
2.134e-02	-3.85	positive regulation of unsaturated fatty acid biosynthetic process	biological process	GO:2001280	8	1	18204	49	CD74
2.134e-02	-3.85	regulation of neutrophil degranulation	biological process	GO:0043313	8	1	18204	49	ITGB2
2.134e-02	-3.85	pyrimidine deoxyribonucleoside monophosphate catabolic process	biological process	GO:0009178	8	1	18204	49	DPYD
2.134e-02	-3.85	regulation of peptidyl-tyrosine phosphorylation	biological process	GO:0050730	220	3	18204	49	CSF1R,CD74,ITGB2
2.140e-02	-3.84	TIG1_plexin	interpro domains	IPR041019	8	1	18521	50	PLXND1
2.140e-02	-3.84	Integrin_bsu_VWA	interpro domains	IPR002369	8	1	18521	50	ITGB2
2.140e-02	-3.84	Tyr_kinase_rcpt_3_CS	interpro domains	IPR001824	8	1	18521	50	CSF1R
2.140e-02	-3.84	GDA1_CD39_NTPase	interpro domains	IPR000407	8	1	18521	50	ENTPD1
2.140e-02	-3.84	Myosin_TH1	interpro domains	IPR010926	8	1	18521	50	MYO1F
2.140e-02	-3.84	Integrin_beta_N	interpro domains	IPR033760	8	1	18521	50	ITGB2
2.146e-02	-3.84	CD4 receptor binding	molecular function	GO:0042609	8	1	18094	49	CD74
2.146e-02	-3.84	inositol tetrakisphosphate phosphatase activity	molecular function	GO:0052743	8	1	18094	49	INPP5D
2.151e-02	-3.84	membrane docking	biological process	GO:0022406	84	2	18204	49	PLEK,VMP1
2.153e-02	-3.84	TAP2 (transporter 2, ATP binding cassette subfamily B member)	protein interactions	6891	88	2	19454	50	UNC93B1,P2RY6
2.159e-02	-3.84	response to insulin	biological process	GO:0032868	221	3	18204	49	ZFP36L1,CYFIP1,GAB1
2.159e-02	-3.84	leukocyte mediated immunity	biological process	GO:0002443	221	3	18204	49	CD74,INPP5D,UNC93B1
2.165e-02	-3.83	establishment of localization	biological process	GO:0051234	3887	17	18204	49	MYO1F,DOCK2,CMTM6,CD68,ELMO1,MARCO,SLCO2B1,CD74,SNX17,VMP1,P2RY6,ZFP36L1,PLEK,ITGB2,PSAP,UNC93B1,HCK
2.182e-02	-3.82	Integrin_alpha	pfam domains	PF00357	8	1	17795	49	ITGAX
2.182e-02	-3.82	Myosin_TH1	pfam domains	PF06017	8	1	17795	49	MYO1F
2.182e-02	-3.82	TIG_plexin	pfam domains	PF17960	8	1	17795	49	PLXND1
2.182e-02	-3.82	Integrin_beta	pfam domains	PF00362	8	1	17795	49	ITGB2
2.182e-02	-3.82	GDA1_CD39	pfam domains	PF01150	8	1	17795	49	ENTPD1
2.182e-02	-3.82	PSI_integrin	pfam domains	PF17205	8	1	17795	49	ITGB2
2.190e-02	-3.82	regulation of cellular process	biological process	GO:0050794	11468	38	18204	49	HCK,UNC93B1,TNFAIP8L2,RASGRP2,ITM2B,VMP1,CD74,CSF3R,ZFP36L1,GAB1,P2RY6,MARCO,ITGAX,RXRA,ELMO1,PLXND1,MLKL,DAPP1,DOCK2,PSAP,FYB1,RAC2,ITGB2,PREX1,MAP3K11,SH2B3,MFNG,THRB,SNX17,PLEK,ABR,RMC1,SPOCK3,RBM47,PLXNC1,CSF1R,INPP5D,CYFIP1
2.193e-02	-3.82	unconventional myosin complex	cellular component	GO:0016461	9	1	19108	47	MYO1F
2.193e-02	-3.82	dendritic growth cone	cellular component	GO:0044294	9	1	19108	47	CYFIP1
2.199e-02	-3.82	ACKR2 (atypical chemokine receptor 2)	protein interactions	1238	89	2	19454	50	UNC93B1,CMTM6
2.199e-02	-3.82	PRMT2 (protein arginine methyltransferase 2)	protein interactions	3275	89	2	19454	50	THRB,RXRA
2.220e-02	-3.81	cell-substrate junction	cellular component	GO:0030055	437	4	19108	47	HCK,CYFIP1,RAC2,ITGB2
2.221e-02	-3.81	regulation of intracellular signal transduction	biological process	GO:1902531	1832	10	18204	49	PREX1,SH2B3,MAP3K11,MARCO,CD74,DOCK2,P2RY6,ABR,PLEK,CSF1R
2.224e-02	-3.81	JAK1 (Janus kinase 1)	protein interactions	3716	234	3	19454	50	INPP5D,GAB1,CSF3R
2.227e-02	-3.80	diffuse_adenocarcinoma	COSMIC cancer mutations	diffuse_adenocarcinoma	4383	18	16828	44	MYO1F,SNX17,PLXND1,PSAP,DPYD,P2RY6,RXRA,ELMO1,PREX1,ITGB2,SH2B3,CPN1,MAP3K11,DOCK2,NCAM2,RBM47,MARCO,MFNG
2.227e-02	-3.80	stomach-carcinoma-diffuse_adenocarcinoma	COSMIC cancer mutations	stomach-carcinoma-diffuse_adenocarcinoma	4383	18	16828	44	P2RY6,PLXND1,PSAP,MYO1F,SNX17,DPYD,SH2B3,ITGB2,ELMO1,RXRA,PREX1,DOCK2,NCAM2,MAP3K11,CPN1,MFNG,RBM47,MARCO
2.242e-02	-3.80	haematopoietic_and_lymphoid_tissue-haematopoietic_neoplasm-myelofibrosis	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue-haematopoietic_neoplasm-myelofibrosis	413	4	16828	44	CSF1R,CSF3R,SH2B3,CD74
2.242e-02	-3.80	myelofibrosis	COSMIC cancer mutations	myelofibrosis	413	4	16828	44	SH2B3,CD74,CSF1R,CSF3R
2.244e-02	-3.80	anchoring junction	cellular component	GO:0070161	902	6	19108	47	RAC2,CYFIP1,HCK,GAB1,ITGB2,FYB1
2.290e-02	-3.78	HLA-DMA (major histocompatibility complex, class II, DM alpha)	protein interactions	3108	9	1	19454	50	CD74
2.290e-02	-3.78	KIF17 (kinesin family member 17)	protein interactions	57576	9	1	19454	50	MAP3K11
2.290e-02	-3.78	SEZ6 (seizure related 6 homolog)	protein interactions	124925	9	1	19454	50	SNX17
2.290e-02	-3.78	RBM46 (RNA binding motif protein 46)	protein interactions	166863	9	1	19454	50	RBM47
2.290e-02	-3.78	SCTR (secretin receptor)	protein interactions	6344	9	1	19454	50	CYFIP1
2.290e-02	-3.78	SLN (sarcolipin)	protein interactions	6588	9	1	19454	50	VMP1
2.290e-02	-3.78	MCTP2 (multiple C2 and transmembrane domain containing 2)	protein interactions	55784	9	1	19454	50	RAC2
2.290e-02	-3.78	FHAD1 (forkhead associated phosphopeptide binding domain 1)	protein interactions	114827	9	1	19454	50	RAC2
2.291e-02	-3.78	enzyme regulator activity	molecular function	GO:0030234	1305	8	18094	49	SPOCK3,ABR,RAC2,ELMO1,DOCK2,PSAP,PREX1,RASGRP2
2.292e-02	-3.78	KHDRBS3 (KH RNA binding domain containing, signal transduction associated 3)	protein interactions	10656	91	2	19454	50	INPP5D,DOCK2
2.292e-02	-3.78	AMIGO1 (adhesion molecule with Ig like domain 1)	protein interactions	57463	91	2	19454	50	ADAM33,ITM2B
2.292e-02	-3.78	PTPRJ (protein tyrosine phosphatase receptor type J)	protein interactions	5795	91	2	19454	50	RAC2,P2RY6
2.299e-02	-3.77	PPP6R3 (protein phosphatase 6 regulatory subunit 3)	protein interactions	55291	237	3	19454	50	ANKRD44,CD74,P2RY6
2.303e-02	-3.77	skin-head_neck-carcinoma-squamous_cell_carcinoma	COSMIC cancer mutations	skin-head_neck-carcinoma-squamous_cell_carcinoma	14191	42	16828	44	THRB,CSF3R,DOCK2,VMP1,NCAM2,RBM47,PLEK,MFNG,GAB1,RAC2,SMPD4,CSF1R,PSAP,DAPP1,PLXNC1,RASGRP2,RXRA,TNFAIP8L2,ABR,PREX1,ITGB2,SPOCK3,CPN1,MAP3K11,MLKL,SLCO2B1,MARCO,ITM2B,CD68,CD74,SNX17,MYO1F,PLXND1,DPYD,HCK,ENTPD1,P2RY6,ANKRD44,ADAM33,ELMO1,SH2B3,ITGAX
2.312e-02	-3.77	STX4 (syntaxin 4)	protein interactions	6810	423	4	19454	50	ITM2B,SMPD4,GAB1,RAC2
2.339e-02	-3.76	WASF1 (WASP family member 1)	protein interactions	8936	92	2	19454	50	RAC2,CYFIP1
2.339e-02	-3.76	MLEC (malectin)	protein interactions	9761	92	2	19454	50	P2RY6,UNC93B1
2.340e-02	-3.76	Signaling events mediated by TCPTP	Pathway Interaction DB	tcptp_pathway	36	2	2226	15	GAB1,CSF1R
2.341e-02	-3.75	immune response-activating cell surface receptor signaling pathway	biological process	GO:0002429	228	3	18204	49	INPP5D,HCK,FYB1
2.344e-02	-3.75	RhoGEF	smart domains	SM00325	68	2	9717	34	ABR,PREX1
2.346e-02	-3.75	regulation of tissue remodeling	biological process	GO:0034103	88	2	18204	49	INPP5D,CSF1R
2.350e-02	-3.75	KRTAP10-9 (keratin associated protein 10-9)	protein interactions	386676	239	3	19454	50	DOCK2,INPP5D,HCK
2.369e-02	-3.74	MET activates PI3K/AKT signaling	REACTOME pathways	R-HSA-8851907	6	1	10285	41	GAB1
2.372e-02	-3.74	monocarboxylic acid binding	molecular function	GO:0033293	88	2	18094	49	PSAP,RXRA
2.372e-02	-3.74	NRAGE signals death through JNK	REACTOME pathways	R-HSA-193648	60	2	10285	41	ABR,PREX1
2.387e-02	-3.74	transport	biological process	GO:0006810	3615	16	18204	49	CMTM6,DOCK2,MYO1F,SLCO2B1,MARCO,ELMO1,PLEK,ZFP36L1,P2RY6,SNX17,VMP1,CD74,HCK,UNC93B1,PSAP,ITGB2
2.387e-02	-3.74	DAB1 (DAB adaptor protein 1)	protein interactions	1600	93	2	19454	50	INPP5D,ITGB2
2.387e-02	-3.74	MAIP1 (matrix AAA peptidase interacting protein 1)	protein interactions	79568	93	2	19454	50	P2RY6,UNC93B1
2.397e-02	-3.73	respiratory burst involved in defense response	biological process	GO:0002679	9	1	18204	49	HCK
2.397e-02	-3.73	negative regulation of antigen processing and presentation	biological process	GO:0002578	9	1	18204	49	CD68
2.397e-02	-3.73	microglial cell proliferation	biological process	GO:0061518	9	1	18204	49	CSF1R
2.397e-02	-3.73	toll-like receptor 9 signaling pathway	biological process	GO:0034162	9	1	18204	49	UNC93B1
2.397e-02	-3.73	establishment of T cell polarity	biological process	GO:0001768	9	1	18204	49	DOCK2
2.397e-02	-3.73	regulation of translation at synapse	biological process	GO:0140243	9	1	18204	49	CYFIP1
2.397e-02	-3.73	peroxisome proliferator activated receptor signaling pathway	biological process	GO:0035357	9	1	18204	49	RXRA
2.397e-02	-3.73	sterol catabolic process	biological process	GO:0016127	9	1	18204	49	SNX17
2.397e-02	-3.73	regulation of mRNA 3'-end processing	biological process	GO:0031440	9	1	18204	49	ZFP36L1
2.397e-02	-3.73	negative regulation of chemokine-mediated signaling pathway	biological process	GO:0070100	9	1	18204	49	SH2B3
2.397e-02	-3.73	cholesterol catabolic process	biological process	GO:0006707	9	1	18204	49	SNX17
2.397e-02	-3.73	macrophage proliferation	biological process	GO:0061517	9	1	18204	49	CSF1R
2.397e-02	-3.73	positive regulation of antigen processing and presentation	biological process	GO:0002579	9	1	18204	49	CD74
2.397e-02	-3.73	transepithelial chloride transport	biological process	GO:0030321	9	1	18204	49	P2RY6
2.397e-02	-3.73	mesendoderm development	biological process	GO:0048382	9	1	18204	49	ZFP36L1
2.397e-02	-3.73	marginal zone B cell differentiation	biological process	GO:0002315	9	1	18204	49	MFNG
2.402e-02	-3.73	CCDC47 (coiled-coil domain containing 47)	protein interactions	57003	428	4	19454	50	RAC2,SMPD4,P2RY6,UNC93B1
2.404e-02	-3.73	BRICHOS_dom	interpro domains	IPR007084	9	1	18521	50	ITM2B
2.404e-02	-3.73	Integrin_bsu	interpro domains	IPR015812	9	1	18521	50	ITGB2
2.407e-02	-3.73	Exopolyphosphatase. Domain 2	gene3d domains	3.30.420.150	8	1	14470	44	ENTPD1
2.412e-02	-3.72	UDP phosphatase activity	molecular function	GO:0045134	9	1	18094	49	ENTPD1
2.422e-02	-3.72	regulation of leukocyte migration	biological process	GO:0002685	231	3	18204	49	CD74,RAC2,CSF1R
2.423e-02	-3.72	lysosomal lumen	cellular component	GO:0043202	98	2	19108	47	PSAP,CD74
2.424e-02	-3.72	Integrin_B_tail	smart domains	SM01242	7	1	9717	34	ITGB2
2.435e-02	-3.72	MPG (N-methylpurine DNA glycosylase)	protein interactions	4350	94	2	19454	50	THRB,RXRA
2.437e-02	-3.71	Insulin Signaling	WikiPathways	WP481	161	3	5310	21	GAB1,MAP3K11,RAC2
2.445e-02	-3.71	HEMATOPO_REC_L_F2	prosite domains	PS01353	7	1	12186	43	CSF3R
2.445e-02	-3.71	SAP_B	prosite domains	PS50015	7	1	12186	43	PSAP
2.446e-02	-3.71	Regulation of actin dynamics for phagocytic cup formation	REACTOME pathways	R-HSA-2029482	61	2	10285	41	ELMO1,CYFIP1
2.452e-02	-3.71	PH_12	pfam domains	PF16457	9	1	17795	49	ELMO1
2.452e-02	-3.71	BRICHOS	pfam domains	PF04089	9	1	17795	49	ITM2B
2.455e-02	-3.71	central_nervous_system-brain-glioma	COSMIC cancer mutations	central_nervous_system-brain-glioma	15470	44	16828	44	RAC2,SMPD4,MFNG,GAB1,RBM47,PLEK,NCAM2,DOCK2,VMP1,CSF3R,THRB,SPOCK3,ITGB2,PREX1,TNFAIP8L2,RXRA,ABR,CMTM6,PLXNC1,RASGRP2,CSF1R,PSAP,DAPP1,CD74,ZFP36L1,CD68,MARCO,ITM2B,SLCO2B1,CPN1,MAP3K11,MLKL,ITGAX,SH2B3,ADAM33,ELMO1,P2RY6,ANKRD44,ENTPD1,HCK,DPYD,SNX17,MYO1F,PLXND1
2.483e-02	-3.70	upper_aerodigestive_tract	COSMIC cancer mutations	upper_aerodigestive_tract	13181	40	16828	44	RBM47,PLEK,RAC2,SMPD4,MFNG,GAB1,CSF3R,THRB,NCAM2,DOCK2,VMP1,PREX1,RXRA,ABR,SPOCK3,ITGB2,PLXNC1,RASGRP2,CSF1R,PSAP,DAPP1,ZFP36L1,MARCO,CD74,SLCO2B1,CPN1,MLKL,MAP3K11,ADAM33,ELMO1,ITGAX,SH2B3,HCK,DPYD,SNX17,MYO1F,PLXND1,P2RY6,ANKRD44,ENTPD1
2.483e-02	-3.70	PCK2 (phosphoenolpyruvate carboxykinase 2, mitochondrial)	protein interactions	5106	95	2	19454	50	RMC1,P2RY6
2.497e-02	-3.69	stomach-adenocarcinoma	COSMIC cancer mutations	stomach-adenocarcinoma	4101	17	16828	44	ELMO1,RXRA,PREX1,ITGAX,SPOCK3,MYO1F,P2RY6,ANKRD44,ITM2B,PLEK,MARCO,ZFP36L1,GAB1,SMPD4,MLKL,DOCK2,NCAM2
2.524e-02	-3.68	DH_2	prosite domains	PS50010	70	2	12186	43	PREX1,ABR
2.529e-02	-3.68	Platelet activation, signaling and aggregation	REACTOME pathways	R-HSA-76002	282	4	10285	41	PSAP,RASGRP2,RAC2,PLEK
2.532e-02	-3.68	LMAN2 (lectin, mannose binding 2)	protein interactions	10960	96	2	19454	50	UNC93B1,P2RY6
2.541e-02	-3.67	STOML3 (stomatin like 3)	protein interactions	161003	10	1	19454	50	ADAM33
2.541e-02	-3.67	SEZ6L (seizure related 6 homolog like)	protein interactions	23544	10	1	19454	50	SNX17
2.541e-02	-3.67	MYO18B (myosin XVIIIB)	protein interactions	84700	10	1	19454	50	RAC2
2.541e-02	-3.67	PLA2G1B (phospholipase A2 group IB)	protein interactions	5319	10	1	19454	50	CSF3R
2.541e-02	-3.67	PGA4 (pepsinogen A4)	protein interactions	643847	10	1	19454	50	CD74
2.541e-02	-3.67	P2rx7 (purinergic receptor P2X 7)	protein interactions	29665	10	1	19454	50	ITGB2
2.547e-02	-3.67	ATG16L1 (autophagy related 16 like 1)	protein interactions	55054	1138	7	19454	50	ANKRD44,PLEK,INPP5D,CYFIP1,DOCK2,ELMO1,SMPD4
2.553e-02	-3.67	chromophobe_renal_cell_carcinoma	COSMIC cancer mutations	chromophobe_renal_cell_carcinoma	430	4	16828	44	HCK,MAP3K11,MLKL,CSF1R
2.553e-02	-3.67	kidney-carcinoma-chromophobe_renal_cell_carcinoma	COSMIC cancer mutations	kidney-carcinoma-chromophobe_renal_cell_carcinoma	430	4	16828	44	HCK,CSF1R,MAP3K11,MLKL
2.555e-02	-3.67	large_intestine-caecum-carcinoma-adenocarcinoma	COSMIC cancer mutations	large_intestine-caecum-carcinoma-adenocarcinoma	14236	42	16828	44	NCAM2,DOCK2,VMP1,CSF3R,THRB,SMPD4,RAC2,MFNG,GAB1,RBM47,PLEK,PLXNC1,RASGRP2,CSF1R,PSAP,DAPP1,SPOCK3,ITGB2,PREX1,RXRA,TNFAIP8L2,ABR,SLCO2B1,CPN1,MAP3K11,MLKL,ZFP36L1,CD68,MARCO,ITM2B,ANKRD44,P2RY6,ENTPD1,DPYD,HCK,SNX17,MYO1F,PLXND1,ITGAX,SH2B3,ADAM33,ELMO1
2.558e-02	-3.67	PICALM (phosphatidylinositol binding clathrin assembly protein)	protein interactions	8301	247	3	19454	50	RAC2,VMP1,RBM47
2.561e-02	-3.66	Golgi membrane	cellular component	GO:0000139	683	5	19108	47	CD74,MFNG,UNC93B1,SMPD4,ITM2B
2.563e-02	-3.66	ruffle membrane	cellular component	GO:0032587	101	2	19108	47	PLEK,RASGRP2
2.581e-02	-3.66	ABL2 (ABL proto-oncogene 2, non-receptor tyrosine kinase)	protein interactions	27	97	2	19454	50	RAC2,HCK
2.581e-02	-3.66	CLPTM1L (CLPTM1 like)	protein interactions	81037	97	2	19454	50	P2RY6,UNC93B1
2.585e-02	-3.66	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-NK_cell_leukaemia	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-NK_cell_leukaemia	10	1	16828	44	CSF3R
2.585e-02	-3.66	NK_cell_leukaemia	COSMIC cancer mutations	NK_cell_leukaemia	10	1	16828	44	CSF3R
2.587e-02	-3.65	regulation of lymphocyte proliferation	biological process	GO:0050670	237	3	18204	49	RAC2,CD74,INPP5D
2.596e-02	-3.65	ovary-other-neoplasm	COSMIC cancer mutations	ovary-other-neoplasm	12717	39	16828	44	CMTM6,RASGRP2,PLXNC1,PSAP,CSF1R,ITGB2,PREX1,ABR,RXRA,NCAM2,DOCK2,VMP1,CSF3R,THRB,RAC2,SMPD4,MFNG,GAB1,PLEK,RBM47,P2RY6,ANKRD44,HCK,DPYD,PLXND1,MYO1F,SNX17,SH2B3,ITGAX,ELMO1,ADAM33,SLCO2B1,MLKL,MAP3K11,CPN1,CD74,ZFP36L1,ITM2B,MARCO
2.598e-02	-3.65	regulation of protein-containing complex assembly	biological process	GO:0043254	419	4	18204	49	PLEK,CYFIP1,PREX1,HCK
2.602e-02	-3.65	upper_leg	COSMIC cancer mutations	upper_leg	880	6	16828	44	DOCK2,DPYD,MAP3K11,CSF1R,ELMO1,ADAM33
2.605e-02	-3.65	SSR1 (signal sequence receptor subunit 1)	protein interactions	6745	439	4	19454	50	PSAP,RAC2,SMPD4,VMP1
2.605e-02	-3.65	ATG9A (autophagy related 9A)	protein interactions	79065	439	4	19454	50	SMPD4,MAP3K11,RMC1,SNX17
2.610e-02	-3.65	breast-carcinoma-ductal_carcinoma	COSMIC cancer mutations	breast-carcinoma-ductal_carcinoma	14824	43	16828	44	RAC2,SMPD4,GAB1,MFNG,PLEK,NCAM2,DOCK2,VMP1,CSF3R,THRB,SPOCK3,ITGB2,PREX1,ABR,RXRA,TNFAIP8L2,CMTM6,RASGRP2,PLXNC1,PSAP,DAPP1,CSF1R,CD74,CD68,ZFP36L1,ITM2B,MARCO,SLCO2B1,MAP3K11,MLKL,CPN1,SH2B3,ITGAX,ELMO1,ADAM33,P2RY6,ANKRD44,ENTPD1,DPYD,HCK,PLXND1,SNX17,MYO1F
2.624e-02	-3.64	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm	7307	26	16828	44	ABR,RXRA,PREX1,ITGB2,CSF1R,PLXNC1,CMTM6,PLEK,MFNG,GAB1,RAC2,THRB,VMP1,DOCK2,NCAM2,ELMO1,ITGAX,SH2B3,PLXND1,MYO1F,DPYD,ANKRD44,MARCO,ZFP36L1,CPN1,SLCO2B1
2.625e-02	-3.64	testis-germ_cell_tumour-seminoma	COSMIC cancer mutations	testis-germ_cell_tumour-seminoma	648	5	16828	44	HCK,MAP3K11,MLKL,ABR,CSF1R
2.626e-02	-3.64	caecum	COSMIC cancer mutations	caecum	14248	42	16828	44	DPYD,HCK,SNX17,MYO1F,PLXND1,ANKRD44,P2RY6,ENTPD1,ADAM33,ELMO1,ITGAX,SH2B3,SLCO2B1,CPN1,MAP3K11,MLKL,ZFP36L1,CD68,MARCO,ITM2B,PLXNC1,RASGRP2,CSF1R,PSAP,DAPP1,PREX1,RXRA,TNFAIP8L2,ABR,SPOCK3,ITGB2,CSF3R,THRB,NCAM2,DOCK2,VMP1,RBM47,PLEK,RAC2,SMPD4,MFNG,GAB1
2.631e-02	-3.64	PLEKHG3 (pleckstrin homology and RhoGEF domain containing G3)	protein interactions	26030	98	2	19454	50	RAC2,VMP1
2.631e-02	-3.64	FRS2 (fibroblast growth factor receptor substrate 2)	protein interactions	10818	98	2	19454	50	RAC2,GAB1
2.660e-02	-3.63	regulation of modification of postsynaptic structure	biological process	GO:0099159	10	1	18204	49	CYFIP1
2.660e-02	-3.63	regulation of vitamin D receptor signaling pathway	biological process	GO:0070562	10	1	18204	49	RXRA
2.660e-02	-3.63	cellular response to salt stress	biological process	GO:0071472	10	1	18204	49	ZFP36L1
2.660e-02	-3.63	dendrite extension	biological process	GO:0097484	10	1	18204	49	CYFIP1
2.660e-02	-3.63	endothelial cell chemotaxis	biological process	GO:0035767	10	1	18204	49	GAB1
2.660e-02	-3.63	establishment of lymphocyte polarity	biological process	GO:0001767	10	1	18204	49	DOCK2
2.660e-02	-3.63	nucleobase catabolic process	biological process	GO:0046113	10	1	18204	49	DPYD
2.660e-02	-3.63	thrombin-activated receptor signaling pathway	biological process	GO:0070493	10	1	18204	49	PLEK
2.668e-02	-3.62	IPPc	interpro domains	IPR000300	10	1	18521	50	INPP5D
2.676e-02	-3.62	glycosphingolipid binding	molecular function	GO:0043208	10	1	18094	49	PSAP
2.676e-02	-3.62	phosphatidylinositol trisphosphate phosphatase activity	molecular function	GO:0034594	10	1	18094	49	INPP5D
2.676e-02	-3.62	mitogen-activated protein kinase kinase binding	molecular function	GO:0031434	10	1	18094	49	MAP3K11
2.676e-02	-3.62	phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity	molecular function	GO:0004439	10	1	18094	49	INPP5D
2.676e-02	-3.62	GDP phosphatase activity	molecular function	GO:0004382	10	1	18094	49	ENTPD1
2.680e-02	-3.62	PRPSAP1 (phosphoribosyl pyrophosphate synthetase associated protein 1)	protein interactions	5635	99	2	19454	50	HCK,ANKRD44
2.680e-02	-3.62	XPO4 (exportin 4)	protein interactions	64328	99	2	19454	50	P2RY6,UNC93B1
2.685e-02	-3.62	KRAS (KRAS proto-oncogene, GTPase)	protein interactions	3845	2876	13	19454	50	GAB1,VMP1,PREX1,HCK,ITM2B,CYFIP1,RAC2,SMPD4,RXRA,RASGRP2,P2RY6,PLXNC1,SLCO2B1
2.693e-02	-3.61	NCK2 (NCK adaptor protein 2)	protein interactions	8440	252	3	19454	50	GAB1,CYFIP1,FYB1
2.704e-02	-3.61	negative regulation of myeloid cell differentiation	biological process	GO:0045638	95	2	18204	49	INPP5D,ZFP36L1
2.704e-02	-3.61	Saposin-like	gene3d domains	1.10.225.10	9	1	14470	44	PSAP
2.718e-02	-3.61	regulation of hemopoiesis	biological process	GO:1903706	425	4	18204	49	INPP5D,CSF3R,ZFP36L1,CD74
2.719e-02	-3.60	Tyr_kinase_AS	interpro domains	IPR008266	95	2	18521	50	CSF1R,HCK
2.730e-02	-3.60	regulation of mononuclear cell proliferation	biological process	GO:0032944	242	3	18204	49	RAC2,CD74,INPP5D
2.731e-02	-3.60	SYNGR1 (synaptogyrin 1)	protein interactions	9145	100	2	19454	50	UNC93B1,CMTM6
2.731e-02	-3.60	TTC27 (tetratricopeptide repeat domain 27)	protein interactions	55622	100	2	19454	50	P2RY6,UNC93B1
2.737e-02	-3.60	response to lipid	biological process	GO:0033993	862	6	18204	49	HCK,RXRA,CPN1,CD68,P2RY6,ZFP36L1
2.737e-02	-3.60	Viral myocarditis	KEGG pathways	hsa05416	58	2	7161	32	RAC2,ITGB2
2.756e-02	-3.59	immunoglobulin mediated immune response	biological process	GO:0016064	96	2	18204	49	INPP5D,CD74
2.763e-02	-3.59	RAC2 (Rac family small GTPase 2)	protein interactions	5880	666	5	19454	50	MAP3K11,VMP1,SMPD4,CYFIP1,DOCK2
2.766e-02	-3.59	INB	smart domains	SM00187	8	1	9717	34	ITGB2
2.772e-02	-3.59	vWFA_dom_sf	interpro domains	IPR036465	96	2	18521	50	ITGB2,ITGAX
2.776e-02	-3.58	MSH6 (mutS homolog 6)	protein interactions	2956	255	3	19454	50	P2RY6,RMC1,UNC93B1
2.780e-02	-3.58	cell surface receptor protein tyrosine kinase signaling pathway	biological process	GO:0007169	428	4	18204	49	SH2B3,GAB1,CSF1R,HCK
2.781e-02	-3.58	LRP5 (LDL receptor related protein 5)	protein interactions	4041	101	2	19454	50	RAC2,ADAM33
2.781e-02	-3.58	NBAS (NBAS subunit of NRZ tethering complex)	protein interactions	51594	101	2	19454	50	UNC93B1,P2RY6
2.781e-02	-3.58	FAR1 (fatty acyl-CoA reductase 1)	protein interactions	84188	101	2	19454	50	UNC93B1,P2RY6
2.789e-02	-3.58	RECEPTOR_TYR_KIN_III	prosite domains	PS00240	8	1	12186	43	CSF1R
2.789e-02	-3.58	TH1	prosite domains	PS51757	8	1	12186	43	MYO1F
2.789e-02	-3.58	GDA1_CD39_NTPASE	prosite domains	PS01238	8	1	12186	43	ENTPD1
2.792e-02	-3.58	GHSR (growth hormone secretagogue receptor)	protein interactions	2693	11	1	19454	50	P2RY6
2.792e-02	-3.58	PLEK (pleckstrin)	protein interactions	5341	11	1	19454	50	PLEK
2.792e-02	-3.58	Gtf2e2 (general transcription factor II E, polypeptide 2 (beta subunit))	protein interactions	68153	11	1	19454	50	CYFIP1
2.792e-02	-3.58	NYAP1 (neuronal tyrosine phosphorylated phosphoinositide-3-kinase adaptor 1)	protein interactions	222950	11	1	19454	50	CYFIP1
2.792e-02	-3.58	RBP7 (retinol binding protein 7)	protein interactions	116362	11	1	19454	50	DAPP1
2.792e-02	-3.58	MS4A7 (membrane spanning 4-domains A7)	protein interactions	58475	11	1	19454	50	ITGB2
2.792e-02	-3.58	LAT2 (linker for activation of T cells family member 2)	protein interactions	7462	11	1	19454	50	GAB1
2.819e-02	-3.57	KRT31 (keratin 31)	protein interactions	3881	450	4	19454	50	DOCK2,INPP5D,HCK,ITGB2
2.825e-02	-3.57	Cytokine Signaling in Immune system	REACTOME pathways	R-HSA-1280215	756	7	10285	41	ITGAX,HCK,ITGB2,INPP5D,MAP3K11,CSF1R,CSF3R
2.832e-02	-3.56	human chr17q23.1	chromosome location	human chr17q23.1	15	1	26134	50	VMP1
2.832e-02	-3.56	human chr3p24.2	chromosome location	human chr3p24.2	15	1	26134	50	THRB
2.832e-02	-3.56	DOCK5 (dedicator of cytokinesis 5)	protein interactions	80005	102	2	19454	50	ELMO1,RAC2
2.832e-02	-3.56	GRAP2 (GRB2 related adaptor protein 2)	protein interactions	9402	102	2	19454	50	GAB1,CSF1R
2.832e-02	-3.56	FASLG (Fas ligand)	protein interactions	356	102	2	19454	50	HCK,FYB1
2.832e-02	-3.56	TMX3 (thioredoxin related transmembrane protein 3)	protein interactions	54495	102	2	19454	50	P2RY6,UNC93B1
2.837e-02	-3.56	acute_lymphoblastic_B_cell_leukaemia	COSMIC cancer mutations	acute_lymphoblastic_B_cell_leukaemia	3828	16	16828	44	SH2B3,ITGB2,ELMO1,CMTM6,ANKRD44,PLXND1,CSF1R,DPYD,GAB1,MARCO,DOCK2,NCAM2,MLKL,THRB,CSF3R,SLCO2B1
2.837e-02	-3.56	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-acute_lymphoblastic_B_cell_leukaemia	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-acute_lymphoblastic_B_cell_leukaemia	3828	16	16828	44	THRB,MLKL,CSF3R,SLCO2B1,DOCK2,NCAM2,MARCO,GAB1,CSF1R,PLXND1,DPYD,CMTM6,ANKRD44,ELMO1,ITGB2,SH2B3
2.841e-02	-3.56	cytokine receptor activity	molecular function	GO:0004896	97	2	18094	49	CSF3R,CD74
2.847e-02	-3.56	positive regulation of neurogenesis	biological process	GO:0050769	246	3	18204	49	PLXND1,PLXNC1,CYFIP1
2.893e-02	-3.54	ovary-carcinoma-clear_cell_carcinoma	COSMIC cancer mutations	ovary-carcinoma-clear_cell_carcinoma	665	5	16828	44	HCK,CSF1R,MLKL,MAP3K11,ITGB2
2.902e-02	-3.54	Joubert Syndrome	SMPDB pathways	SMP0000582	20	1	1369	2	INPP5D
2.902e-02	-3.54	Phosphatidylinositol Phosphate Metabolism	SMPDB pathways	SMP0000463	20	1	1369	2	INPP5D
2.913e-02	-3.54	SCAR complex	cellular component	GO:0031209	12	1	19108	47	CYFIP1
2.922e-02	-3.53	prostate gland growth	biological process	GO:0060736	11	1	18204	49	PSAP
2.922e-02	-3.53	pyrimidine deoxyribonucleoside monophosphate metabolic process	biological process	GO:0009176	11	1	18204	49	DPYD
2.922e-02	-3.53	regulation of neurotrophin TRK receptor signaling pathway	biological process	GO:0051386	11	1	18204	49	CYFIP1
2.922e-02	-3.53	retinal cone cell development	biological process	GO:0046549	11	1	18204	49	THRB
2.922e-02	-3.53	deoxyribonucleoside metabolic process	biological process	GO:0009120	11	1	18204	49	DPYD
2.922e-02	-3.53	heme catabolic process	biological process	GO:0042167	11	1	18204	49	SLCO2B1
2.922e-02	-3.53	leukocyte aggregation	biological process	GO:0070486	11	1	18204	49	RAC2
2.922e-02	-3.53	positive regulation of chemokine (C-X-C motif) ligand 2 production	biological process	GO:2000343	11	1	18204	49	CD74
2.922e-02	-3.53	epithelial cell differentiation involved in prostate gland development	biological process	GO:0060742	11	1	18204	49	PSAP
2.922e-02	-3.53	positive regulation of integrin activation	biological process	GO:0033625	11	1	18204	49	PLEK
2.922e-02	-3.53	negative regulation of platelet aggregation	biological process	GO:0090331	11	1	18204	49	SH2B3
2.922e-02	-3.53	pigment catabolic process	biological process	GO:0046149	11	1	18204	49	SLCO2B1
2.922e-02	-3.53	pinocytosis	biological process	GO:0006907	11	1	18204	49	DOCK2
2.928e-02	-3.53	Pathways in cancer	KEGG pathways	hsa05200	395	5	7161	32	RASGRP2,CSF1R,RAC2,CSF3R,RXRA
2.931e-02	-3.53	DOCK_C_lobe_C	interpro domains	IPR043162	11	1	18521	50	DOCK2
2.931e-02	-3.53	DOCKER_Lobe_B	interpro domains	IPR046770	11	1	18521	50	DOCK2
2.931e-02	-3.53	C2_DOCK-type_domain	interpro domains	IPR027007	11	1	18521	50	DOCK2
2.931e-02	-3.53	DOCK	interpro domains	IPR026791	11	1	18521	50	DOCK2
2.931e-02	-3.53	DOCKER_Lobe_A	interpro domains	IPR046769	11	1	18521	50	DOCK2
2.931e-02	-3.53	DOCK_C_lobe_A	interpro domains	IPR043161	11	1	18521	50	DOCK2
2.931e-02	-3.53	OATP	interpro domains	IPR004156	11	1	18521	50	SLCO2B1
2.931e-02	-3.53	DOCKER_dom	interpro domains	IPR027357	11	1	18521	50	DOCK2
2.931e-02	-3.53	DOCKER_Lobe_C	interpro domains	IPR046773	11	1	18521	50	DOCK2
2.936e-02	-3.53	LRRFIP2 (LRR binding FLII interacting protein 2)	protein interactions	9209	104	2	19454	50	RXRA,VMP1
2.936e-02	-3.53	CTDSP1 (CTD small phosphatase 1)	protein interactions	58190	104	2	19454	50	CSF1R,RAC2
2.940e-02	-3.53	complement component C3b binding	molecular function	GO:0001851	11	1	18094	49	ITGB2
2.940e-02	-3.53	nitric-oxide synthase binding	molecular function	GO:0050998	11	1	18094	49	CD74
2.940e-02	-3.53	JUN kinase kinase kinase activity	molecular function	GO:0004706	11	1	18094	49	MAP3K11
2.940e-02	-3.53	T cell receptor binding	molecular function	GO:0042608	11	1	18094	49	DOCK2
2.951e-02	-3.52	non_small_cell_carcinoma	COSMIC cancer mutations	non_small_cell_carcinoma	5198	20	16828	44	MFNG,GAB1,RAC2,VMP1,MLKL,MAP3K11,THRB,CPN1,ITGAX,ITGB2,ABR,ADAM33,PREX1,ANKRD44,PLXND1,CSF1R,SNX17,HCK,RASGRP2,DPYD
2.951e-02	-3.52	lung-carcinoma-non_small_cell_carcinoma	COSMIC cancer mutations	lung-carcinoma-non_small_cell_carcinoma	5198	20	16828	44	SNX17,CSF1R,PLXND1,RASGRP2,HCK,DPYD,ANKRD44,ADAM33,ABR,PREX1,ITGB2,ITGAX,CPN1,THRB,MAP3K11,MLKL,VMP1,MFNG,GAB1,RAC2
2.956e-02	-3.52	positive regulation of cellular component organization	biological process	GO:0051130	1122	7	18204	49	PLXNC1,HCK,RAC2,PLXND1,PLEK,CYFIP1,DOCK2
2.959e-02	-3.52	clear_cell_carcinoma	COSMIC cancer mutations	clear_cell_carcinoma	669	5	16828	44	HCK,MAP3K11,MLKL,CSF1R,ITGB2
2.961e-02	-3.52	NUP155 (nucleoporin 155)	protein interactions	9631	457	4	19454	50	SMPD4,VMP1,P2RY6,RAC2
2.967e-02	-3.52	cellular response to peptide hormone stimulus	biological process	GO:0071375	250	3	18204	49	GAB1,CYFIP1,ZFP36L1
2.972e-02	-3.52	positive regulation of interleukin-6 production	biological process	GO:0032755	100	2	18204	49	UNC93B1,CD74
2.972e-02	-3.52	regulation of dendrite development	biological process	GO:0050773	100	2	18204	49	PREX1,CYFIP1
2.988e-02	-3.51	BZW2 (basic leucine zipper and W2 domains 2)	protein interactions	28969	105	2	19454	50	CD68,CYFIP1
2.988e-02	-3.51	CIAO2B (cytosolic iron-sulfur assembly component 2B)	protein interactions	51647	105	2	19454	50	UNC93B1,P2RY6
2.988e-02	-3.51	SLC27A4 (solute carrier family 27 member 4)	protein interactions	10999	105	2	19454	50	UNC93B1,P2RY6
2.988e-02	-3.51	DOCK-C2	pfam domains	PF14429	11	1	17795	49	DOCK2
2.988e-02	-3.51	DHR-2_Lobe_C	pfam domains	PF20421	11	1	17795	49	DOCK2
2.988e-02	-3.51	DHR-2_Lobe_A	pfam domains	PF06920	11	1	17795	49	DOCK2
2.988e-02	-3.51	OATP	pfam domains	PF03137	11	1	17795	49	SLCO2B1
2.988e-02	-3.51	DHR-2_Lobe_B	pfam domains	PF20422	11	1	17795	49	DOCK2
2.993e-02	-3.51	Integrin cell surface interactions	REACTOME pathways	R-HSA-216083	68	2	10285	41	ITGAX,ITGB2
3.000e-02	-3.51	Cytochrome c1, transmembrane anchor, C-terminal	gene3d domains	1.20.5.100	10	1	14470	44	ITGB2
3.027e-02	-3.50	B cell mediated immunity	biological process	GO:0019724	101	2	18204	49	INPP5D,CD74
3.027e-02	-3.50	platelet activation	biological process	GO:0030168	101	2	18204	49	PLEK,ENTPD1
3.027e-02	-3.50	regulation of carbohydrate biosynthetic process	biological process	GO:0043255	101	2	18204	49	PLEK,P2RY6
3.040e-02	-3.49	side of membrane	cellular component	GO:0098552	715	5	19108	47	HCK,ITGAX,CD74,CSF3R,ITGB2
3.040e-02	-3.49	NSD1 (nuclear receptor binding SET domain protein 1)	protein interactions	64324	106	2	19454	50	THRB,RXRA
3.042e-02	-3.49	SELP (selectin P)	protein interactions	6403	12	1	19454	50	SNX17
3.042e-02	-3.49	CCZ1B (CCZ1 homolog B, vacuolar protein trafficking and biogenesis associated)	protein interactions	221960	12	1	19454	50	RMC1
3.042e-02	-3.49	PDC (phosducin)	protein interactions	5132	12	1	19454	50	PLXNC1
3.042e-02	-3.49	TENM4 (teneurin transmembrane protein 4)	protein interactions	26011	12	1	19454	50	DOCK2
3.042e-02	-3.49	FUT4 (fucosyltransferase 4)	protein interactions	2526	12	1	19454	50	ITGB2
3.042e-02	-3.49	ROPN1L (rhophilin associated tail protein 1 like)	protein interactions	83853	12	1	19454	50	CD74
3.042e-02	-3.49	PNMT (phenylethanolamine N-methyltransferase)	protein interactions	5409	12	1	19454	50	HCK
3.042e-02	-3.49	AMPD3 (adenosine monophosphate deaminase 3)	protein interactions	272	12	1	19454	50	ITGB2
3.042e-02	-3.49	ADGRB3 (adhesion G protein-coupled receptor B3)	protein interactions	577	12	1	19454	50	ELMO1
3.058e-02	-3.49	regulation of transporter activity	biological process	GO:0032409	253	3	18204	49	P2RY6,RXRA,VMP1
3.078e-02	-3.48	ovary-carcinoma-mucinous_carcinoma	COSMIC cancer mutations	ovary-carcinoma-mucinous_carcinoma	456	4	16828	44	MLKL,MAP3K11,CSF1R,HCK
3.081e-02	-3.48	stomach	COSMIC cancer mutations	stomach	15550	44	16828	44	GAB1,MFNG,RAC2,SMPD4,RBM47,PLEK,VMP1,DOCK2,NCAM2,THRB,CSF3R,ITGB2,SPOCK3,RXRA,TNFAIP8L2,ABR,PREX1,CMTM6,CSF1R,DAPP1,PSAP,PLXNC1,RASGRP2,CD74,MARCO,ITM2B,ZFP36L1,CD68,CPN1,MAP3K11,MLKL,SLCO2B1,SH2B3,ITGAX,ADAM33,ELMO1,ENTPD1,P2RY6,ANKRD44,MYO1F,SNX17,PLXND1,DPYD,HCK
3.082e-02	-3.48	artery development	biological process	GO:0060840	102	2	18204	49	PLXND1,SNX17
3.082e-02	-3.48	regulation of phagocytosis	biological process	GO:0050764	102	2	18204	49	DOCK2,HCK
3.092e-02	-3.48	GEMIN4 (gem nuclear organelle associated protein 4)	protein interactions	50628	266	3	19454	50	UNC93B1,P2RY6,CD74
3.092e-02	-3.48	TRIP13 (thyroid hormone receptor interactor 13)	protein interactions	9319	266	3	19454	50	UNC93B1,THRB,P2RY6
3.092e-02	-3.48	COPB1 (COPI coat complex subunit beta 1)	protein interactions	1315	266	3	19454	50	CD74,P2RY6,UNC93B1
3.093e-02	-3.48	VMA21 (vacuolar ATPase assembly factor VMA21)	protein interactions	203547	107	2	19454	50	RAC2,ADAM33
3.093e-02	-3.48	IQGAP2 (IQ motif containing GTPase activating protein 2)	protein interactions	10788	107	2	19454	50	UNC93B1,CD74
3.093e-02	-3.48	TPP2 (tripeptidyl peptidase 2)	protein interactions	7174	107	2	19454	50	P2RY6,CD74
3.093e-02	-3.48	RPL39 (ribosomal protein L39)	protein interactions	6170	107	2	19454	50	P2RY6,VMP1
3.094e-02	-3.48	haematopoietic_and_lymphoid_tissue-lymph_node-lymphoid_neoplasm-angioimmunoblastic_T_cell_lymphoma	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue-lymph_node-lymphoid_neoplasm-angioimmunoblastic_T_cell_lymphoma	12	1	16828	44	CSF1R
3.100e-02	-3.47	RHOA (ras homolog family member A)	protein interactions	387	1186	7	19454	50	GAB1,RAC2,VMP1,SMPD4,CYFIP1,PREX1,ABR
3.101e-02	-3.47	regulation of neuron projection development	biological process	GO:0010975	443	4	18204	49	PLXNC1,PLXND1,CYFIP1,PREX1
3.107e-02	-3.47	MCAM (melanoma cell adhesion molecule)	protein interactions	4162	464	4	19454	50	CYFIP1,GAB1,RAC2,LRMDA
3.107e-02	-3.47	BRICHOS	smart domains	SM01039	9	1	9717	34	ITM2B
3.121e-02	-3.47	mucinous_carcinoma	COSMIC cancer mutations	mucinous_carcinoma	458	4	16828	44	HCK,CSF1R,MAP3K11,MLKL
3.125e-02	-3.47	regulation of biological process	biological process	GO:0050789	12079	39	18204	49	GAB1,P2RY6,CSF3R,ZFP36L1,CD74,VMP1,TNFAIP8L2,HCK,UNC93B1,ITM2B,RASGRP2,PLXND1,DAPP1,MLKL,CD68,DOCK2,ITGAX,MARCO,RXRA,ELMO1,MFNG,THRB,RMC1,ABR,PLEK,SNX17,PSAP,SH2B3,MAP3K11,PREX1,ITGB2,FYB1,RAC2,INPP5D,CSF1R,CYFIP1,PLXNC1,SPOCK3,RBM47
3.132e-02	-3.46	BRICHOS	prosite domains	PS50869	9	1	12186	43	ITM2B
3.132e-02	-3.46	INTEGRIN_BETA	prosite domains	PS00243	9	1	12186	43	ITGB2
3.138e-02	-3.46	erythrocyte differentiation	biological process	GO:0030218	103	2	18204	49	RAC2,SH2B3
3.142e-02	-3.46	ion binding	molecular function	GO:0043167	6007	23	18094	49	ENTPD1,THRB,MLKL,RASGRP2,ITM2B,ZFP36L1,ITGB2,ADAM33,RXRA,MYO1F,SPOCK3,PLEK,MFNG,CSF1R,CPN1,SMPD4,ITGAX,PSAP,MAP3K11,DPYD,RAC2,HCK,DAPP1
3.146e-02	-3.46	Phosphate bond hydrolysis by NTPDase proteins	REACTOME pathways	R-HSA-8850843	8	1	10285	41	ENTPD1
3.146e-02	-3.46	endometrium-carcinoma-serous_carcinoma	COSMIC cancer mutations	endometrium-carcinoma-serous_carcinoma	1442	8	16828	44	PLXNC1,HCK,ENTPD1,RXRA,ELMO1,PLEK,SMPD4,SPOCK3
3.147e-02	-3.46	TYW1 (tRNA-yW synthesizing protein 1 homolog)	protein interactions	55253	108	2	19454	50	RAC2,ADAM33
3.152e-02	-3.46	dendrite terminus	cellular component	GO:0044292	13	1	19108	47	CYFIP1
3.152e-02	-3.46	early phagosome	cellular component	GO:0032009	13	1	19108	47	UNC93B1
3.168e-02	-3.45	TyrKc	smart domains	SM00219	80	2	9717	34	HCK,CSF1R
3.181e-02	-3.45	SRPRA (SRP receptor subunit alpha)	protein interactions	6734	269	3	19454	50	RMC1,P2RY6,RAC2
3.184e-02	-3.45	response to macrophage colony-stimulating factor	biological process	GO:0036005	12	1	18204	49	CSF1R
3.184e-02	-3.45	cytidine to uridine editing	biological process	GO:0016554	12	1	18204	49	RBM47
3.184e-02	-3.45	regulation of chemokine-mediated signaling pathway	biological process	GO:0070099	12	1	18204	49	SH2B3
3.184e-02	-3.45	cellular response to thyroid hormone stimulus	biological process	GO:0097067	12	1	18204	49	THRB
3.184e-02	-3.45	regulation of prostaglandin biosynthetic process	biological process	GO:0031392	12	1	18204	49	CD74
3.193e-02	-3.44	FAD/NAD-binding_dom	interpro domains	IPR023753	12	1	18521	50	DPYD
3.194e-02	-3.44	regulation of chemokine production	biological process	GO:0032642	104	2	18204	49	CSF1R,CD74
3.194e-02	-3.44	epithelial cell migration	biological process	GO:0010631	104	2	18204	49	GAB1,PLXND1
3.200e-02	-3.44	NHSL3 (NHS like 3)	protein interactions	57648	109	2	19454	50	RAC2,CYFIP1
3.200e-02	-3.44	COQ8B (coenzyme Q8B)	protein interactions	79934	109	2	19454	50	P2RY6,UNC93B1
3.200e-02	-3.44	TMEM109 (transmembrane protein 109)	protein interactions	79073	109	2	19454	50	RAC2,UNC93B1
3.200e-02	-3.44	B4GAT1 (beta-1,4-glucuronyltransferase 1)	protein interactions	11041	109	2	19454	50	CMTM6,UNC93B1
3.203e-02	-3.44	prostaglandin transmembrane transporter activity	molecular function	GO:0015132	12	1	18094	49	SLCO2B1
3.203e-02	-3.44	phosphatidylinositol-4,5-bisphosphate phosphatase activity	molecular function	GO:0106019	12	1	18094	49	INPP5D
3.251e-02	-3.43	response to type II interferon	biological process	GO:0034341	105	2	18204	49	HCK,CD74
3.251e-02	-3.43	antigen processing and presentation	biological process	GO:0019882	105	2	18204	49	UNC93B1,CD74
3.251e-02	-3.43	gland morphogenesis	biological process	GO:0022612	105	2	18204	49	CSF1R,PLXND1
3.252e-02	-3.43	ovary-carcinoma-endometrioid_carcinoma	COSMIC cancer mutations	ovary-carcinoma-endometrioid_carcinoma	464	4	16828	44	HCK,MAP3K11,MLKL,CSF1R
3.254e-02	-3.43	PLXNA1 (plexin A1)	protein interactions	5361	110	2	19454	50	RAC2,PLXND1
3.254e-02	-3.43	SLC27A2 (solute carrier family 27 member 2)	protein interactions	11001	110	2	19454	50	P2RY6,UNC93B1
3.254e-02	-3.43	NOTCH3 (notch receptor 3)	protein interactions	4854	110	2	19454	50	ANKRD44,ADAM33
3.254e-02	-3.43	ARHGAP39 (Rho GTPase activating protein 39)	protein interactions	80728	110	2	19454	50	NCAM2,RAC2
3.256e-02	-3.42	CarboxypepD_reg	pfam domains	PF13620	12	1	17795	49	CPN1
3.256e-02	-3.42	Pyr_redox_2	pfam domains	PF07992	12	1	17795	49	DPYD
3.275e-02	-3.42	regulation of plasma membrane bounded cell projection organization	biological process	GO:0120035	666	5	18204	49	PLXNC1,PLXND1,CYFIP1,PREX1,RAC2
3.291e-02	-3.41	KCNQ4 (potassium voltage-gated channel subfamily Q member 4)	protein interactions	9132	13	1	19454	50	CSF1R
3.291e-02	-3.41	MRNIP (MRN complex interacting protein)	protein interactions	51149	13	1	19454	50	ANKRD44
3.291e-02	-3.41	CLYBL (citramalyl-CoA lyase)	protein interactions	171425	13	1	19454	50	INPP5D
3.291e-02	-3.41	PRSS56 (serine protease 56)	protein interactions	646960	13	1	19454	50	RMC1
3.291e-02	-3.41	MYO16 (myosin XVI)	protein interactions	23026	13	1	19454	50	CYFIP1
3.291e-02	-3.41	SEMA4A (semaphorin 4A)	protein interactions	64218	13	1	19454	50	PLXND1
3.291e-02	-3.41	C1orf74 (chromosome 1 open reading frame 74)	protein interactions	148304	13	1	19454	50	HCK
3.291e-02	-3.41	SCG3 (secretogranin III)	protein interactions	29106	13	1	19454	50	NCAM2
3.291e-02	-3.41	GGT6 (gamma-glutamyltransferase 6)	protein interactions	124975	13	1	19454	50	ADAM33
3.296e-02	-3.41	-	gene3d domains	1.20.58.740	11	1	14470	44	DOCK2
3.296e-02	-3.41	Carboxypeptidase-like, regulatory domain	gene3d domains	2.60.40.1120	11	1	14470	44	CPN1
3.296e-02	-3.41	-	gene3d domains	1.25.40.410	11	1	14470	44	DOCK2
3.306e-02	-3.41	angioimmunoblastic_T_cell_lymphoma	COSMIC cancer mutations	angioimmunoblastic_T_cell_lymphoma	269	3	16828	44	SH2B3,CSF1R,HCK
3.320e-02	-3.41	INTEGRINB	prints domains	PR01186	8	1	5227	22	ITGB2
3.333e-02	-3.40	PANX1 (pannexin 1)	protein interactions	24145	274	3	19454	50	VMP1,SMPD4,RAC2
3.333e-02	-3.40	MNGIE (Mitochondrial Neurogastrointestinal Encephalopathy)	SMPDB pathways	SMP0000202	23	1	1369	2	DPYD
3.333e-02	-3.40	Pyrimidine Metabolism	SMPDB pathways	SMP0000046	23	1	1369	2	DPYD
3.333e-02	-3.40	UMP Synthase Deficiency (Orotic Aciduria)	SMPDB pathways	SMP0000219	23	1	1369	2	DPYD
3.333e-02	-3.40	beta-Ureidopropionase Deficiency	SMPDB pathways	SMP0000172	23	1	1369	2	DPYD
3.333e-02	-3.40	Dihydropyrimidinase Deficiency	SMPDB pathways	SMP0000178	23	1	1369	2	DPYD
3.341e-02	-3.40	immune response-regulating cell surface receptor signaling pathway	biological process	GO:0002768	262	3	18204	49	FYB1,INPP5D,HCK
3.346e-02	-3.40	pleura	COSMIC cancer mutations	pleura	4914	19	16828	44	PREX1,ADAM33,SH2B3,ITGAX,ITGB2,DPYD,HCK,RASGRP2,CSF1R,SNX17,ANKRD44,RAC2,MFNG,GAB1,MAP3K11,MLKL,CPN1,THRB,VMP1
3.349e-02	-3.40	phosphate-containing compound metabolic process	biological process	GO:0006796	1681	9	18204	49	SMPD4,DAPP1,INPP5D,CSF1R,DPYD,PLEK,ENTPD1,HCK,MAP3K11
3.363e-02	-3.39	GLG1 (golgi glycoprotein 1)	protein interactions	2734	112	2	19454	50	MLKL,ITM2B
3.363e-02	-3.39	SIGLECL1 (SIGLEC family like 1)	protein interactions	284369	112	2	19454	50	CMTM6,ITM2B
3.365e-02	-3.39	T cell receptor signaling pathway	biological process	GO:0050852	107	2	18204	49	FYB1,INPP5D
3.365e-02	-3.39	epithelium migration	biological process	GO:0090132	107	2	18204	49	PLXND1,GAB1
3.374e-02	-3.39	regulation of phosphate metabolic process	biological process	GO:0019220	1154	7	18204	49	CD74,P2RY6,PLEK,CSF1R,ITGB2,MAP3K11,MARCO
3.379e-02	-3.39	positive regulation of cell differentiation	biological process	GO:0045597	906	6	18204	49	ZFP36L1,CYFIP1,CD74,INPP5D,PLXND1,PLXNC1
3.388e-02	-3.38	regulation of phosphorus metabolic process	biological process	GO:0051174	1155	7	18204	49	CSF1R,CD74,P2RY6,PLEK,MARCO,ITGB2,MAP3K11
3.396e-02	-3.38	regulation of nervous system development	biological process	GO:0051960	456	4	18204	49	PLXNC1,PLXND1,ITGAX,CYFIP1
3.418e-02	-3.38	DOK2 (docking protein 2)	protein interactions	9046	113	2	19454	50	HCK,INPP5D
3.420e-02	-3.38	prostate-carcinoma	COSMIC cancer mutations	prostate-carcinoma	9000	30	16828	44	ELMO1,ITGAX,MYO1F,PLXND1,DPYD,HCK,ENTPD1,P2RY6,ANKRD44,MARCO,ZFP36L1,MAP3K11,SLCO2B1,RXRA,ABR,PREX1,SPOCK3,CSF1R,PSAP,PLXNC1,RBM47,GAB1,MFNG,SMPD4,RAC2,THRB,CSF3R,DOCK2,VMP1,NCAM2
3.422e-02	-3.37	cardiac septum development	biological process	GO:0003279	108	2	18204	49	PLXND1,SNX17
3.444e-02	-3.37	enucleate erythrocyte differentiation	biological process	GO:0043353	13	1	18204	49	RAC2
3.444e-02	-3.37	positive regulation of inositol phosphate biosynthetic process	biological process	GO:0060732	13	1	18204	49	P2RY6
3.444e-02	-3.37	type II interferon-mediated signaling pathway	biological process	GO:0060333	13	1	18204	49	HCK
3.444e-02	-3.37	G protein-coupled purinergic nucleotide receptor signaling pathway	biological process	GO:0035589	13	1	18204	49	P2RY6
3.444e-02	-3.37	positive regulation of actin filament depolymerization	biological process	GO:0030836	13	1	18204	49	PLEK
3.444e-02	-3.37	positive regulation of platelet activation	biological process	GO:0010572	13	1	18204	49	PLEK
3.444e-02	-3.37	negative regulation of homotypic cell-cell adhesion	biological process	GO:0034111	13	1	18204	49	SH2B3
3.444e-02	-3.37	retinal cone cell differentiation	biological process	GO:0042670	13	1	18204	49	THRB
3.444e-02	-3.37	porphyrin-containing compound catabolic process	biological process	GO:0006787	13	1	18204	49	SLCO2B1
3.444e-02	-3.37	tetrapyrrole catabolic process	biological process	GO:0033015	13	1	18204	49	SLCO2B1
3.446e-02	-3.37	IPPc	smart domains	SM00128	10	1	9717	34	INPP5D
3.447e-02	-3.37	SH3_1	pfam domains	PF00018	106	2	17795	49	HCK,MYO1F
3.465e-02	-3.36	G protein-coupled purinergic nucleotide receptor activity	molecular function	GO:0045028	13	1	18094	49	P2RY6
3.465e-02	-3.36	phosphatidylinositol phosphate 5-phosphatase activity	molecular function	GO:0034595	13	1	18094	49	INPP5D
3.465e-02	-3.36	diacylglycerol binding	molecular function	GO:0019992	13	1	18094	49	RASGRP2
3.465e-02	-3.36	inositol trisphosphate phosphatase activity	molecular function	GO:0046030	13	1	18094	49	INPP5D
3.465e-02	-3.36	icosanoid transmembrane transporter activity	molecular function	GO:0071714	13	1	18094	49	SLCO2B1
3.465e-02	-3.36	RNA 7-methylguanosine cap binding	molecular function	GO:0000340	13	1	18094	49	CYFIP1
3.474e-02	-3.36	ATP5MF (ATP synthase membrane subunit f)	protein interactions	9551	114	2	19454	50	P2RY6,UNC93B1
3.500e-02	-3.35	seminoma	COSMIC cancer mutations	seminoma	700	5	16828	44	HCK,MLKL,MAP3K11,ABR,CSF1R
3.519e-02	-3.35	actin filament	cellular component	GO:0005884	120	2	19108	47	HCK,RAC2
3.520e-02	-3.35	SNRPE (small nuclear ribonucleoprotein polypeptide E)	protein interactions	6635	280	3	19454	50	UNC93B1,CD74,P2RY6
3.520e-02	-3.35	TSG101 (tumor susceptibility 101)	protein interactions	7251	280	3	19454	50	THRB,HCK,MLKL
3.522e-02	-3.35	response to organonitrogen compound	biological process	GO:0010243	915	6	18204	49	ITGB2,ZFP36L1,CYFIP1,GAB1,P2RY6,CD68
3.523e-02	-3.35	haematopoietic_and_lymphoid_tissue-lymph_node-lymphoid_neoplasm-mantle_cell_lymphoma	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue-lymph_node-lymphoid_neoplasm-mantle_cell_lymphoma	476	4	16828	44	DOCK2,NCAM2,SPOCK3,DPYD
3.525e-02	-3.35	kidney-other-neoplasm	COSMIC cancer mutations	kidney-other-neoplasm	10653	34	16828	44	SLCO2B1,MAP3K11,MLKL,CPN1,ITM2B,MARCO,ANKRD44,DPYD,HCK,PLXND1,MYO1F,SH2B3,ITGAX,ELMO1,ADAM33,NCAM2,DOCK2,VMP1,CSF3R,THRB,SMPD4,RAC2,GAB1,MFNG,PLEK,RASGRP2,PLXNC1,PSAP,CSF1R,SPOCK3,ITGB2,PREX1,ABR,RXRA
3.539e-02	-3.34	negative regulation of leukocyte differentiation	biological process	GO:1902106	110	2	18204	49	CD74,INPP5D
3.539e-02	-3.34	HRAS (HRas proto-oncogene, GTPase)	protein interactions	3265	712	5	19454	50	SNX17,ABR,ITM2B,CYFIP1,GAB1
3.540e-02	-3.34	CPN1 (carboxypeptidase N subunit 1)	protein interactions	1369	14	1	19454	50	CPN1
3.540e-02	-3.34	FFAR3 (free fatty acid receptor 3)	protein interactions	2865	14	1	19454	50	UNC93B1
3.540e-02	-3.34	HHLA2 (HHLA2 member of B7 family)	protein interactions	11148	14	1	19454	50	UNC93B1
3.540e-02	-3.34	SCGB3A1 (secretoglobin family 3A member 1)	protein interactions	92304	14	1	19454	50	MARCO
3.540e-02	-3.34	MON1A (MON1 homolog A, secretory trafficking associated)	protein interactions	84315	14	1	19454	50	RMC1
3.540e-02	-3.34	TPSAB1 (tryptase alpha/beta 1)	protein interactions	7177	14	1	19454	50	P2RY6
3.540e-02	-3.34	ITGAL (integrin subunit alpha L)	protein interactions	3683	14	1	19454	50	ITGB2
3.540e-02	-3.34	COPZ2 (COPI coat complex subunit zeta 2)	protein interactions	51226	14	1	19454	50	SNX17
3.540e-02	-3.34	CYP1B1 (cytochrome P450 family 1 subfamily B member 1)	protein interactions	1545	14	1	19454	50	RAC2
3.540e-02	-3.34	PARM1 (prostate androgen-regulated mucin-like protein 1)	protein interactions	25849	14	1	19454	50	SNX17
3.540e-02	-3.34	CSF3 (colony stimulating factor 3)	protein interactions	1440	14	1	19454	50	CSF3R
3.551e-02	-3.34	EPHA7 (EPH receptor A7)	protein interactions	2045	281	3	19454	50	CSF1R,CYFIP1,RAC2
3.572e-02	-3.33	Fc epsilon RI signaling pathway	KEGG pathways	ko04664	67	2	7161	32	INPP5D,RAC2
3.572e-02	-3.33	Fc epsilon RI signaling pathway	KEGG pathways	hsa04664	67	2	7161	32	INPP5D,RAC2
3.593e-02	-3.33	regulation of cell projection organization	biological process	GO:0031344	683	5	18204	49	PREX1,RAC2,CYFIP1,PLXNC1,PLXND1
3.615e-02	-3.32	HLA-A (major histocompatibility complex, class I, A)	protein interactions	3105	283	3	19454	50	RAC2,ADAM33,ITM2B
3.615e-02	-3.32	SOAT1 (sterol O-acyltransferase 1)	protein interactions	6646	283	3	19454	50	RAC2,VMP1,ADAM33
3.642e-02	-3.31	EMC3 (ER membrane protein complex subunit 3)	protein interactions	55831	117	2	19454	50	RAC2,P2RY6
3.647e-02	-3.31	phosphorus metabolic process	biological process	GO:0006793	1707	9	18204	49	PLEK,DPYD,CSF1R,INPP5D,SMPD4,DAPP1,MAP3K11,ENTPD1,HCK
3.657e-02	-3.31	erythrocyte homeostasis	biological process	GO:0034101	112	2	18204	49	SH2B3,RAC2
3.670e-02	-3.30	Cell death signalling via NRAGE, NRIF and NADE	REACTOME pathways	R-HSA-204998	76	2	10285	41	PREX1,ABR
3.680e-02	-3.30	CIAO1 (cytosolic iron-sulfur assembly component 1)	protein interactions	9391	285	3	19454	50	SMPD4,P2RY6,UNC93B1
3.704e-02	-3.30	positive regulation of actin nucleation	biological process	GO:0051127	14	1	18204	49	CYFIP1
3.704e-02	-3.30	alpha-beta T cell proliferation	biological process	GO:0046633	14	1	18204	49	DOCK2
3.704e-02	-3.30	toll-like receptor 3 signaling pathway	biological process	GO:0034138	14	1	18204	49	UNC93B1
3.704e-02	-3.30	regulation of podosome assembly	biological process	GO:0071801	14	1	18204	49	HCK
3.704e-02	-3.30	cellular response to purine-containing compound	biological process	GO:0071415	14	1	18204	49	P2RY6
3.704e-02	-3.30	deoxyribonucleoside monophosphate catabolic process	biological process	GO:0009159	14	1	18204	49	DPYD
3.704e-02	-3.30	regulation of unsaturated fatty acid biosynthetic process	biological process	GO:2001279	14	1	18204	49	CD74
3.704e-02	-3.30	regulation of modification of synaptic structure	biological process	GO:1905244	14	1	18204	49	CYFIP1
3.704e-02	-3.30	positive regulation by symbiont of entry into host	biological process	GO:0075294	14	1	18204	49	CD74
3.704e-02	-3.30	positive regulation of viral entry into host cell	biological process	GO:0046598	14	1	18204	49	CD74
3.704e-02	-3.30	cellular response to oxidised low-density lipoprotein particle stimulus	biological process	GO:0140052	14	1	18204	49	CD68
3.704e-02	-3.30	immunological synapse formation	biological process	GO:0001771	14	1	18204	49	DOCK2
3.713e-02	-3.29	G protein-coupled receptor signaling pathway	biological process	GO:0007186	1178	7	18204	49	MARCO,PSAP,PREX1,RAC2,P2RY6,SH2B3,PLEK
3.717e-02	-3.29	positive regulation of plasma membrane bounded cell projection assembly	biological process	GO:0120034	113	2	18204	49	RAC2,CYFIP1
3.717e-02	-3.29	regulation of regulated secretory pathway	biological process	GO:1903305	113	2	18204	49	ITGB2,RAC2
3.717e-02	-3.29	tissue migration	biological process	GO:0090130	113	2	18204	49	PLXND1,GAB1
3.727e-02	-3.29	metalloendopeptidase inhibitor activity	molecular function	GO:0008191	14	1	18094	49	SPOCK3
3.727e-02	-3.29	Toll-like receptor binding	molecular function	GO:0035325	14	1	18094	49	UNC93B1
3.756e-02	-3.28	NOP9 (NOP9 nucleolar protein)	protein interactions	161424	119	2	19454	50	P2RY6,RBM47
3.756e-02	-3.28	HLA-DPA1 (major histocompatibility complex, class II, DP alpha 1)	protein interactions	3113	119	2	19454	50	CD74,PLXNC1
3.758e-02	-3.28	signaling adaptor activity	molecular function	GO:0035591	113	2	18094	49	GAB1,SH2B3
3.759e-02	-3.28	human chr3p22.3	chromosome location	human chr3p22.3	20	1	26134	50	CMTM6
3.762e-02	-3.28	GTPase activator activity	molecular function	GO:0005096	273	3	18094	49	ABR,DOCK2,PREX1
3.774e-02	-3.28	defense response to virus	biological process	GO:0051607	275	3	18204	49	UNC93B1,MLKL,ITGAX
3.779e-02	-3.28	VDAC1 (voltage dependent anion channel 1)	protein interactions	7416	494	4	19454	50	UNC93B1,RMC1,P2RY6,CD74
3.783e-02	-3.27	testis-germ_cell_tumour-non_seminoma	COSMIC cancer mutations	testis-germ_cell_tumour-non_seminoma	487	4	16828	44	CSF1R,MLKL,MAP3K11,HCK
3.788e-02	-3.27	GLIPR1 (GLI pathogenesis related 1)	protein interactions	11010	15	1	19454	50	CMTM6
3.788e-02	-3.27	PTPRCAP (protein tyrosine phosphatase receptor type C associated protein)	protein interactions	5790	15	1	19454	50	CMTM6
3.788e-02	-3.27	GALNT3 (polypeptide N-acetylgalactosaminyltransferase 3)	protein interactions	2591	15	1	19454	50	UNC93B1
3.788e-02	-3.27	GCK (glucokinase)	protein interactions	2645	15	1	19454	50	CSF3R
3.788e-02	-3.27	SPATA6 (spermatogenesis associated 6)	protein interactions	54558	15	1	19454	50	SNX17
3.788e-02	-3.27	UCP3 (uncoupling protein 3)	protein interactions	7352	15	1	19454	50	RBM47
3.788e-02	-3.27	CASTOR1 (cytosolic arginine sensor for mTORC1 subunit 1)	protein interactions	652968	15	1	19454	50	RXRA
3.788e-02	-3.27	AANAT (aralkylamine N-acetyltransferase)	protein interactions	15	15	1	19454	50	P2RY6
3.788e-02	-3.27	NYAP2 (neuronal tyrosine-phosphorylated phosphoinositide-3-kinase adaptor 2)	protein interactions	57624	15	1	19454	50	CYFIP1
3.788e-02	-3.27	NCKAP1L (NCK associated protein 1 like)	protein interactions	3071	15	1	19454	50	CYFIP1
3.788e-02	-3.27	ENTPD1 (ectonucleoside triphosphate diphosphohydrolase 1)	protein interactions	953	15	1	19454	50	ANKRD44
3.814e-02	-3.27	CLPTM1 (CLPTM1 regulator of GABA type A receptor forward trafficking)	protein interactions	1209	120	2	19454	50	MFNG,UNC93B1
3.814e-02	-3.27	ANKRD13A (ankyrin repeat domain 13A)	protein interactions	88455	120	2	19454	50	P2RY6,UNC93B1
3.814e-02	-3.27	PJA1 (praja ring finger ubiquitin ligase 1)	protein interactions	64219	120	2	19454	50	ABR,ENTPD1
3.815e-02	-3.27	DOCKER	prosite domains	PS51651	11	1	12186	43	DOCK2
3.815e-02	-3.27	C2_DOCK	prosite domains	PS51650	11	1	12186	43	DOCK2
3.818e-02	-3.27	transcription coregulator binding	molecular function	GO:0001221	114	2	18094	49	THRB,RXRA
3.853e-02	-3.26	actin cytoskeleton	cellular component	GO:0015629	520	4	19108	47	FYB1,MYO1F,HCK,RAC2
3.865e-02	-3.25	asymmetric, glutamatergic, excitatory synapse	cellular component	GO:0098985	16	1	19108	47	PLXNC1
3.872e-02	-3.25	EIF3J (eukaryotic translation initiation factor 3 subunit J)	protein interactions	8669	121	2	19454	50	CD74,P2RY6
3.876e-02	-3.25	CSE1L (chromosome segregation 1 like)	protein interactions	1434	291	3	19454	50	UNC93B1,RMC1,P2RY6
3.876e-02	-3.25	GOPC (golgi associated PDZ and coiled-coil motif containing)	protein interactions	57120	291	3	19454	50	HCK,DPYD,CSF1R
3.887e-02	-3.25	right_lower_lobe	COSMIC cancer mutations	right_lower_lobe	5692	21	16828	44	PSAP,PLXND1,DAPP1,MYO1F,CSF1R,RASGRP2,DPYD,PLXNC1,ANKRD44,P2RY6,ELMO1,ADAM33,PREX1,ITGAX,DOCK2,PLEK,MARCO,ZFP36L1,GAB1,MFNG,SMPD4
3.887e-02	-3.25	lung-right_lower_lobe-carcinoma-adenocarcinoma	COSMIC cancer mutations	lung-right_lower_lobe-carcinoma-adenocarcinoma	5692	21	16828	44	PLEK,MARCO,ZFP36L1,MFNG,GAB1,SMPD4,DOCK2,ELMO1,ADAM33,PREX1,ITGAX,PSAP,DAPP1,PLXND1,MYO1F,CSF1R,RASGRP2,DPYD,PLXNC1,ANKRD44,P2RY6
3.888e-02	-3.25	Liver X Receptor Pathway	WikiPathways	WP2874	10	1	5310	21	RXRA
3.888e-02	-3.25	Vitamin D Metabolism	WikiPathways	WP1531	10	1	5310	21	RXRA
3.888e-02	-3.25	Steroid Biosynthesis	WikiPathways	WP496	10	1	5310	21	CPN1
3.894e-02	-3.25	localization	biological process	GO:0051179	4474	18	18204	49	HCK,PSAP,UNC93B1,FYB1,ITGB2,ZFP36L1,PLEK,P2RY6,SNX17,VMP1,CD74,SLCO2B1,MARCO,ELMO1,CD68,CMTM6,MYO1F,DOCK2
3.905e-02	-3.24	non_seminoma	COSMIC cancer mutations	non_seminoma	492	4	16828	44	HCK,MAP3K11,MLKL,CSF1R
3.911e-02	-3.24	Adaptive Immune System	REACTOME pathways	R-HSA-1280218	810	7	10285	41	DAPP1,FYB1,INPP5D,GAB1,ITGB2,CD74,RASGRP2
3.917e-02	-3.24	MET receptor recycling	REACTOME pathways	R-HSA-8875656	10	1	10285	41	GAB1
3.917e-02	-3.24	Signaling by FGFR3 fusions in cancer	REACTOME pathways	R-HSA-8853334	10	1	10285	41	GAB1
3.929e-02	-3.24	skin-carcinoma-squamous_cell_carcinoma	COSMIC cancer mutations	skin-carcinoma-squamous_cell_carcinoma	493	4	16828	44	SH2B3,CSF1R,ZFP36L1,DPYD
3.930e-02	-3.24	BRK1 (BRICK1 subunit of SCAR/WAVE actin nucleating complex)	protein interactions	55845	122	2	19454	50	CYFIP1,RAC2
3.938e-02	-3.23	PI Metabolism	REACTOME pathways	R-HSA-1483255	79	2	10285	41	TNFAIP8L2,INPP5D
3.943e-02	-3.23	KRTAP10-3 (keratin associated protein 10-3)	protein interactions	386682	293	3	19454	50	P2RY6,INPP5D,DOCK2
3.943e-02	-3.23	human chr2q14.2	chromosome location	human chr2q14.2	21	1	26134	50	MARCO
3.943e-02	-3.23	human chr21q21.1	chromosome location	human chr21q21.1	21	1	26134	50	NCAM2
3.943e-02	-3.23	human chr4q32.3	chromosome location	human chr4q32.3	21	1	26134	50	SPOCK3
3.959e-02	-3.23	negative regulation of hemopoiesis	biological process	GO:1903707	117	2	18204	49	CD74,INPP5D
3.964e-02	-3.23	sodium-independent organic anion transport	biological process	GO:0043252	15	1	18204	49	SLCO2B1
3.964e-02	-3.23	UMP metabolic process	biological process	GO:0046049	15	1	18204	49	DPYD
3.964e-02	-3.23	positive regulation of ruffle assembly	biological process	GO:1900029	15	1	18204	49	CYFIP1
3.964e-02	-3.23	protein homotrimerization	biological process	GO:0070207	15	1	18204	49	MLKL
3.964e-02	-3.23	negative regulation of DNA damage response, signal transduction by p53 class mediator	biological process	GO:0043518	15	1	18204	49	CD74
3.964e-02	-3.23	negative regulation of B cell apoptotic process	biological process	GO:0002903	15	1	18204	49	CD74
3.964e-02	-3.23	p38MAPK cascade	biological process	GO:0038066	15	1	18204	49	ZFP36L1
3.964e-02	-3.23	positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay	biological process	GO:1900153	15	1	18204	49	ZFP36L1
3.964e-02	-3.23	negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator	biological process	GO:1902166	15	1	18204	49	CD74
3.964e-02	-3.23	ribonucleoside monophosphate catabolic process	biological process	GO:0009158	15	1	18204	49	DPYD
3.988e-02	-3.22	nuclear vitamin D receptor binding	molecular function	GO:0042809	15	1	18094	49	RXRA
3.988e-02	-3.22	phospholipid scramblase activity	molecular function	GO:0017128	15	1	18094	49	VMP1
3.988e-02	-3.22	ITPR1 (inositol 1,4,5-trisphosphate receptor type 1)	protein interactions	3708	123	2	19454	50	VMP1,RAC2
3.999e-02	-3.22	amb2 Integrin signaling	Pathway Interaction DB	amb2_neutrophils_pathway	48	2	2226	15	ITGB2,HCK
4.020e-02	-3.21	positive regulation of calcium ion transport	biological process	GO:0051928	118	2	18204	49	P2RY6,VMP1
4.023e-02	-3.21	Prot_kinase_dom	interpro domains	IPR000719	480	4	18521	50	MAP3K11,MLKL,CSF1R,HCK
4.035e-02	-3.21	APOA5 (apolipoprotein A5)	protein interactions	116519	16	1	19454	50	CMTM6
4.035e-02	-3.21	CASTOR2 (cytosolic arginine sensor for mTORC1 subunit 2)	protein interactions	729438	16	1	19454	50	RXRA
4.035e-02	-3.21	ESM1 (endothelial cell specific molecule 1)	protein interactions	11082	16	1	19454	50	ITGB2
4.035e-02	-3.21	IL1RL2 (interleukin 1 receptor like 2)	protein interactions	8808	16	1	19454	50	MYO1F
4.035e-02	-3.21	GMPR2 (guanosine monophosphate reductase 2)	protein interactions	51292	16	1	19454	50	SNX17
4.035e-02	-3.21	ZSCAN4 (zinc finger and SCAN domain containing 4)	protein interactions	201516	16	1	19454	50	HCK
4.035e-02	-3.21	BEST2 (bestrophin 2)	protein interactions	54831	16	1	19454	50	UNC93B1
4.035e-02	-3.21	SLCO3A1 (solute carrier organic anion transporter family member 3A1)	protein interactions	28232	16	1	19454	50	RAC2
4.047e-02	-3.21	DAB2 (DAB adaptor protein 2)	protein interactions	1601	124	2	19454	50	INPP5D,RAC2
4.047e-02	-3.21	ERLEC1 (endoplasmic reticulum lectin 1)	protein interactions	27248	124	2	19454	50	UNC93B1,P2RY6
4.102e-02	-3.19	MHC class II protein complex	cellular component	GO:0042613	17	1	19108	47	CD74
4.104e-02	-3.19	normal	COSMIC cancer mutations	normal	16	1	16828	44	CSF1R
4.113e-02	-3.19	UBR4 (ubiquitin protein ligase E3 component n-recognin 4)	protein interactions	23352	298	3	19454	50	P2RY6,CD74,UNC93B1
4.113e-02	-3.19	GPR45 (G protein-coupled receptor 45)	protein interactions	11250	298	3	19454	50	SMPD4,VMP1,CMTM6
4.113e-02	-3.19	ALDH3A2 (aldehyde dehydrogenase 3 family member A2)	protein interactions	224	298	3	19454	50	RAC2,P2RY6,UNC93B1
4.115e-02	-3.19	small GTPase binding	molecular function	GO:0031267	283	3	18094	49	MAP3K11,DOCK2,CYFIP1
4.119e-02	-3.19	CYSRT1 (cysteine rich tail 1)	protein interactions	375791	508	4	19454	50	ITGB2,HCK,DOCK2,INPP5D
4.126e-02	-3.19	response to steroid hormone	biological process	GO:0048545	285	3	18204	49	CPN1,ZFP36L1,RXRA
4.127e-02	-3.19	human chr4q23	chromosome location	human chr4q23	22	1	26134	50	DAPP1
4.140e-02	-3.18	testis	COSMIC cancer mutations	testis	733	5	16828	44	HCK,ABR,MAP3K11,MLKL,CSF1R
4.144e-02	-3.18	RHOH (ras homolog family member H)	protein interactions	399	509	4	19454	50	SMPD4,PREX1,ITM2B,CYFIP1
4.155e-02	-3.18	lung-carcinoid-endocrine_tumour	COSMIC cancer mutations	lung-carcinoid-endocrine_tumour	502	4	16828	44	HCK,MLKL,MAP3K11,CSF1R
4.194e-02	-3.17	IFITM3 (interferon induced transmembrane protein 3)	protein interactions	10410	511	4	19454	50	ITM2B,CD74,SNX17,RMC1
4.223e-02	-3.16	cellular response to prostaglandin E stimulus	biological process	GO:0071380	16	1	18204	49	P2RY6
4.223e-02	-3.16	negative regulation of B cell proliferation	biological process	GO:0030889	16	1	18204	49	INPP5D
4.223e-02	-3.16	non-proteinogenic amino acid biosynthetic process	biological process	GO:0170043	16	1	18204	49	DPYD
4.223e-02	-3.16	pyrimidine ribonucleoside monophosphate metabolic process	biological process	GO:0009173	16	1	18204	49	DPYD
4.223e-02	-3.16	neuron cell-cell adhesion	biological process	GO:0007158	16	1	18204	49	NCAM2
4.223e-02	-3.16	modification of synaptic structure	biological process	GO:0099563	16	1	18204	49	CYFIP1
4.223e-02	-3.16	negative regulation of bone resorption	biological process	GO:0045779	16	1	18204	49	INPP5D
4.223e-02	-3.16	prostaglandin transport	biological process	GO:0015732	16	1	18204	49	SLCO2B1
4.223e-02	-3.16	positive regulation of B cell differentiation	biological process	GO:0045579	16	1	18204	49	INPP5D
4.223e-02	-3.16	regulation of granulocyte differentiation	biological process	GO:0030852	16	1	18204	49	INPP5D
4.223e-02	-3.16	neutrophil homeostasis	biological process	GO:0001780	16	1	18204	49	SH2B3
4.223e-02	-3.16	positive regulation of dendrite development	biological process	GO:1900006	16	1	18204	49	CYFIP1
4.223e-02	-3.16	branching involved in salivary gland morphogenesis	biological process	GO:0060445	16	1	18204	49	PLXND1
4.226e-02	-3.16	CSNK1G3 (casein kinase 1 gamma 3)	protein interactions	1456	127	2	19454	50	RAC2,CYFIP1
4.226e-02	-3.16	GOLPH3 (golgi phosphoprotein 3)	protein interactions	64083	127	2	19454	50	UNC93B1,P2RY6
4.234e-02	-3.16	positive regulation of innate immune response	biological process	GO:0045089	288	3	18204	49	UNC93B1,HCK,RBM47
4.235e-02	-3.16	CarboxyPept-like_regulatory	interpro domains	IPR008969	16	1	18521	50	CPN1
4.235e-02	-3.16	Disintegrin_CS	interpro domains	IPR018358	16	1	18521	50	ADAM33
4.235e-02	-3.16	Integrin_alpha_C_CS	interpro domains	IPR018184	16	1	18521	50	ITGAX
4.235e-02	-3.16	Integrin_alpha_Ig-like_1	interpro domains	IPR013649	16	1	18521	50	ITGAX
4.248e-02	-3.16	mitogen-activated protein kinase kinase kinase binding	molecular function	GO:0031435	16	1	18094	49	MAP3K11
4.248e-02	-3.16	sodium-independent organic anion transmembrane transporter activity	molecular function	GO:0015347	16	1	18094	49	SLCO2B1
4.269e-02	-3.15	Nucleotide GPCRs	WikiPathways	WP80	11	1	5310	21	P2RY6
4.275e-02	-3.15	lower_third	COSMIC cancer mutations	lower_third	7961	27	16828	44	ITGAX,SH2B3,ELMO1,P2RY6,ANKRD44,PLXND1,MYO1F,DPYD,ITM2B,MARCO,MLKL,CPN1,SLCO2B1,ITGB2,SPOCK3,RXRA,TNFAIP8L2,PREX1,DAPP1,CSF1R,PLXNC1,RAC2,DOCK2,VMP1,NCAM2,THRB,CSF3R
4.282e-02	-3.15	PSD4 (pleckstrin and Sec7 domain containing 4)	protein interactions	23550	17	1	19454	50	SNX17
4.282e-02	-3.15	FAM163B (family with sequence similarity 163 member B)	protein interactions	642968	17	1	19454	50	PLXNC1
4.282e-02	-3.15	TMEM95 (transmembrane protein 95)	protein interactions	339168	17	1	19454	50	CMTM6
4.282e-02	-3.15	ARL4A (ADP ribosylation factor like GTPase 4A)	protein interactions	10124	17	1	19454	50	ELMO1
4.282e-02	-3.15	CGB2 (chorionic gonadotropin subunit beta 2)	protein interactions	114336	17	1	19454	50	CYFIP1
4.282e-02	-3.15	SYNDIG1 (synapse differentiation inducing 1)	protein interactions	79953	17	1	19454	50	UNC93B1
4.282e-02	-3.15	SMIM11 (small integral membrane protein 11)	protein interactions	54065	17	1	19454	50	UNC93B1
4.286e-02	-3.15	FARP1 (FERM, ARH/RhoGEF and pleckstrin domain protein 1)	protein interactions	10160	128	2	19454	50	RAC2,RBM47
4.286e-02	-3.15	MAP4K1 (mitogen-activated protein kinase kinase kinase kinase 1)	protein interactions	11184	128	2	19454	50	MAP3K11,DAPP1
4.286e-02	-3.15	GAB2 (GRB2 associated binding protein 2)	protein interactions	9846	128	2	19454	50	GAB1,INPP5D
4.286e-02	-3.15	ASPH (aspartate beta-hydroxylase)	protein interactions	444	303	3	19454	50	CMTM6,UNC93B1,P2RY6
4.296e-02	-3.15	phospholipid binding	molecular function	GO:0005543	489	4	18094	49	SNX17,DAPP1,PREX1,PSAP
4.297e-02	-3.15	RAC1 (Rac family small GTPase 1)	protein interactions	5879	1005	6	19454	50	GAB1,RAC2,CYFIP1,DOCK2,MAP3K11,PREX1
4.301e-02	-3.15	MET activates RAP1 and RAC1	REACTOME pathways	R-HSA-8875555	11	1	10285	41	GAB1
4.301e-02	-3.15	Signaling by FGFR4 in disease	REACTOME pathways	R-HSA-5655291	11	1	10285	41	GAB1
4.301e-02	-3.15	Import of palmitoyl-CoA into the mitochondrial matrix	REACTOME pathways	R-HSA-200425	11	1	10285	41	RXRA
4.309e-02	-3.14	lung-carcinoid-endocrine_tumour-atypical	COSMIC cancer mutations	lung-carcinoid-endocrine_tumour-atypical	508	4	16828	44	MLKL,MAP3K11,CSF1R,HCK
4.309e-02	-3.14	Signaling events mediated by PTP1B	Pathway Interaction DB	ptp1bpathway	50	2	2226	15	HCK,CSF1R
4.311e-02	-3.14	human chr14q24.1	chromosome location	human chr14q24.1	23	1	26134	50	ZFP36L1
4.313e-02	-3.14	protein homodimerization activity	molecular function	GO:0042803	714	5	18094	49	MAP3K11,PLEK,DPYD,PSAP,CSF1R
4.317e-02	-3.14	SH3 domain binding	molecular function	GO:0017124	122	2	18094	49	ELMO1,INPP5D
4.318e-02	-3.14	Integrin_A_Ig_1	pfam domains	PF08441	16	1	17795	49	ITGAX
4.333e-02	-3.14	PROTEIN_KINASE_TYR	prosite domains	PS00109	94	2	12186	43	HCK,CSF1R
4.338e-02	-3.14	NADPH oxidase complex	cellular component	GO:0043020	18	1	19108	47	RAC2
4.355e-02	-3.13	chronic_eosinophilic_leukaemia-hypereosinophilic_syndrome	COSMIC cancer mutations	chronic_eosinophilic_leukaemia-hypereosinophilic_syndrome	17	1	16828	44	SH2B3
4.355e-02	-3.13	haematopoietic_and_lymphoid_tissue-haematopoietic_neoplasm-chronic_eosinophilic_leukaemia-hypereosinophilic_syndrome	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue-haematopoietic_neoplasm-chronic_eosinophilic_leukaemia-hypereosinophilic_syndrome	17	1	16828	44	SH2B3
4.367e-02	-3.13	anatomical structure formation involved in morphogenesis	biological process	GO:0048646	964	6	18204	49	MFNG,PLXND1,ITGB2,DOCK2,GAB1,CSF3R
4.380e-02	-3.13	bone-humerus-other-chondroblastoma	COSMIC cancer mutations	bone-humerus-other-chondroblastoma	301	3	16828	44	VMP1,DOCK2,DPYD
4.381e-02	-3.13	glycerophospholipid metabolic process	biological process	GO:0006650	292	3	18204	49	PLEK,INPP5D,SMPD4
4.407e-02	-3.12	ABCC1 (ATP binding cassette subfamily C member 1 (ABCC1 blood group))	protein interactions	4363	130	2	19454	50	RAC2,UNC93B1
4.407e-02	-3.12	ARHGEF1 (Rho guanine nucleotide exchange factor 1)	protein interactions	9138	130	2	19454	50	CYFIP1,PLEK
4.409e-02	-3.12	CDC42 (cell division cycle 42)	protein interactions	998	1280	7	19454	50	SNX17,CYFIP1,SMPD4,RAC2,CPN1,PREX1,MAP3K11
4.421e-02	-3.12	Tuberculosis	KEGG pathways	ko05152	178	3	7161	32	CD74,ITGAX,ITGB2
4.421e-02	-3.12	Tuberculosis	KEGG pathways	hsa05152	178	3	7161	32	CD74,ITGB2,ITGAX
4.424e-02	-3.12	Ig-like_fold	interpro domains	IPR013783	721	5	18521	50	NCAM2,PLXND1,PLXNC1,CSF3R,CSF1R
4.429e-02	-3.12	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-mantle_cell_lymphoma	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-mantle_cell_lymphoma	2737	12	16828	44	ANKRD44,NCAM2,DOCK2,DPYD,RASGRP2,MYO1F,SPOCK3,GAB1,PREX1,ELMO1,ABR,PLEK
4.446e-02	-3.11	endometrium-carcinoma-endometrioid_carcinoma	COSMIC cancer mutations	endometrium-carcinoma-endometrioid_carcinoma	15680	44	16828	44	CD68,ITM2B,CD74,SLCO2B1,CPN1,MLKL,ADAM33,ELMO1,DPYD,HCK,P2RY6,ENTPD1,RAC2,THRB,VMP1,PREX1,ITGB2,PLXNC1,RASGRP2,CSF1R,DAPP1,CMTM6,ZFP36L1,MARCO,MAP3K11,SH2B3,ITGAX,MYO1F,SNX17,PLXND1,ANKRD44,RBM47,PLEK,SMPD4,GAB1,MFNG,CSF3R,NCAM2,DOCK2,RXRA,TNFAIP8L2,ABR,SPOCK3,PSAP
4.456e-02	-3.11	small molecule binding	molecular function	GO:0036094	6197	23	18094	49	RASGRP2,ITM2B,MLKL,ENTPD1,THRB,ITGB2,ADAM33,RXRA,ZFP36L1,SMPD4,ITGAX,PSAP,MAP3K11,DPYD,CSF1R,CPN1,MYO1F,SPOCK3,PLEK,MFNG,HCK,DAPP1,RAC2
4.459e-02	-3.11	regulation of anatomical structure size	biological process	GO:0090066	498	4	18204	49	PREX1,PLEK,CYFIP1,HCK
4.468e-02	-3.11	ATP6V1H (ATPase H+ transporting V1 subunit H)	protein interactions	51606	131	2	19454	50	UNC93B1,P2RY6
4.468e-02	-3.11	EIF2B1 (eukaryotic translation initiation factor 2B subunit alpha)	protein interactions	1967	131	2	19454	50	UNC93B1,RBM47
4.468e-02	-3.11	LGALS7 (galectin 7)	protein interactions	3963	131	2	19454	50	GAB1,RMC1
4.468e-02	-3.11	NCOA2 (nuclear receptor coactivator 2)	protein interactions	10499	131	2	19454	50	RXRA,THRB
4.481e-02	-3.11	regulation of integrin activation	biological process	GO:0033623	17	1	18204	49	PLEK
4.481e-02	-3.11	protein kinase C signaling	biological process	GO:0070528	17	1	18204	49	PLEK
4.481e-02	-3.11	regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator	biological process	GO:1902165	17	1	18204	49	CD74
4.481e-02	-3.11	pyrimidine nucleoside catabolic process	biological process	GO:0046135	17	1	18204	49	DPYD
4.481e-02	-3.11	regulation of respiratory burst	biological process	GO:0060263	17	1	18204	49	RAC2
4.481e-02	-3.11	monocyte differentiation	biological process	GO:0030224	17	1	18204	49	CSF1R
4.481e-02	-3.11	response to hepatocyte growth factor	biological process	GO:0035728	17	1	18204	49	GAB1
4.492e-02	-3.10	Bacterial invasion of epithelial cells	KEGG pathways	ko05100	76	2	7161	32	ELMO1,GAB1
4.492e-02	-3.10	Bacterial invasion of epithelial cells	KEGG pathways	hsa05100	76	2	7161	32	GAB1,ELMO1
4.493e-02	-3.10	regulation of endocytosis	biological process	GO:0030100	295	3	18204	49	HCK,DOCK2,SNX17
4.493e-02	-3.10	myeloid cell differentiation	biological process	GO:0030099	295	3	18204	49	CSF1R,SH2B3,RAC2
4.493e-02	-3.10	atypical	COSMIC cancer mutations	atypical	515	4	16828	44	HCK,MLKL,MAP3K11,CSF1R
4.494e-02	-3.10	CARBOXYPEPT_ZN_1	prosite domains	PS00132	13	1	12186	43	CPN1
4.494e-02	-3.10	CARBOXYPEPT_ZN_2	prosite domains	PS00133	13	1	12186	43	CPN1
4.507e-02	-3.10	transmembrane receptor protein tyrosine kinase adaptor activity	molecular function	GO:0005068	17	1	18094	49	SH2B3
4.507e-02	-3.10	nucleoside diphosphate phosphatase activity	molecular function	GO:0017110	17	1	18094	49	ENTPD1
4.509e-02	-3.10	protein tyrosine kinase binding	molecular function	GO:1990782	125	2	18094	49	SH2B3,ITGAX
4.514e-02	-3.10	positive regulation of cytokine production	biological process	GO:0001819	500	4	18204	49	RBM47,CSF1R,UNC93B1,CD74
4.514e-02	-3.10	regulation of cell-cell adhesion	biological process	GO:0022407	500	4	18204	49	TNFAIP8L2,CD74,ITGB2,SH2B3
4.524e-02	-3.10	RPN2 (ribophorin II)	protein interactions	6185	762	5	19454	50	VMP1,SMPD4,P2RY6,RAC2,UNC93B1
4.529e-02	-3.09	SLC2A14 (solute carrier family 2 member 14)	protein interactions	144195	18	1	19454	50	RAC2
4.529e-02	-3.09	PDE8A (phosphodiesterase 8A)	protein interactions	5151	18	1	19454	50	RAC2
4.529e-02	-3.09	TM4SF20 (transmembrane 4 L six family member 20)	protein interactions	79853	18	1	19454	50	CD74
4.529e-02	-3.09	NAALADL2 (N-acetylated alpha-linked acidic dipeptidase like 2)	protein interactions	254827	18	1	19454	50	ITM2B
4.529e-02	-3.09	MVB12B (multivesicular body subunit 12B)	protein interactions	89853	18	1	19454	50	MLKL
4.529e-02	-3.09	DCAF17 (DDB1 and CUL4 associated factor 17)	protein interactions	80067	18	1	19454	50	PREX1
4.529e-02	-3.09	PMF1-BGLAP (PMF1-BGLAP readthrough)	protein interactions	100527963	18	1	19454	50	CMTM6
4.529e-02	-3.09	FKBP8 (FKBP prolyl isomerase 8)	protein interactions	23770	524	4	19454	50	RAC2,SMPD4,CD74,P2RY6
4.530e-02	-3.09	SPECC1 (sperm antigen with calponin homology and coiled-coil domains 1)	protein interactions	92521	132	2	19454	50	RAC2,VMP1
4.530e-02	-3.09	TXNDC12 (thioredoxin domain containing 12)	protein interactions	51060	132	2	19454	50	HCK,PSAP
4.531e-02	-3.09	positive regulation of nervous system development	biological process	GO:0051962	296	3	18204	49	PLXND1,PLXNC1,CYFIP1
4.535e-02	-3.09	C11orf52 (chromosome 11 open reading frame 52)	protein interactions	91894	310	3	19454	50	CYFIP1,GAB1,RMC1
4.573e-02	-3.08	endometrioid_carcinoma	COSMIC cancer mutations	endometrioid_carcinoma	15690	44	16828	44	ITGB2,SPOCK3,TNFAIP8L2,RXRA,ABR,PREX1,CMTM6,CSF1R,PSAP,DAPP1,PLXNC1,RASGRP2,GAB1,MFNG,RAC2,SMPD4,RBM47,PLEK,VMP1,DOCK2,NCAM2,THRB,CSF3R,ITGAX,SH2B3,ADAM33,ELMO1,ENTPD1,ANKRD44,P2RY6,MYO1F,SNX17,PLXND1,DPYD,HCK,CD74,MARCO,ITM2B,ZFP36L1,CD68,CPN1,MAP3K11,MLKL,SLCO2B1
4.574e-02	-3.08	filopodium tip	cellular component	GO:0032433	19	1	19108	47	CYFIP1
4.591e-02	-3.08	PIGS (phosphatidylinositol glycan anchor biosynthesis class S)	protein interactions	94005	133	2	19454	50	RAC2,UNC93B1
4.599e-02	-3.08	endometrium	COSMIC cancer mutations	endometrium	15692	44	16828	44	MAP3K11,MARCO,ZFP36L1,ANKRD44,SNX17,MYO1F,PLXND1,ITGAX,SH2B3,DOCK2,NCAM2,CSF3R,GAB1,MFNG,SMPD4,RBM47,PLEK,PSAP,SPOCK3,TNFAIP8L2,RXRA,ABR,CPN1,MLKL,SLCO2B1,CD74,ITM2B,CD68,ENTPD1,P2RY6,DPYD,HCK,ADAM33,ELMO1,VMP1,THRB,RAC2,CMTM6,CSF1R,DAPP1,PLXNC1,RASGRP2,ITGB2,PREX1
4.607e-02	-3.08	ILK (integrin linked kinase)	protein interactions	3611	312	3	19454	50	SH2B3,ITGB2,RMC1
4.616e-02	-3.08	cellular localization	biological process	GO:0051641	2660	12	18204	49	PLEK,CD74,VMP1,SNX17,UNC93B1,HCK,PSAP,ITGB2,FYB1,CD68,CMTM6,DOCK2
4.619e-02	-3.07	protein-containing complex binding	molecular function	GO:0044877	1772	9	18094	49	ITGB2,FYB1,MYO1F,THRB,MLKL,CYFIP1,ITGAX,DOCK2,CD74
4.629e-02	-3.07	Signaling events mediated by Stem cell factor receptor (c-Kit)	Pathway Interaction DB	kitpathway	52	2	2226	15	SH2B3,GAB1
4.649e-02	-3.07	RalA downstream regulated genes	WikiPathways	WP2290	12	1	5310	21	RAC2
4.652e-02	-3.07	cellular response to organonitrogen compound	biological process	GO:0071417	505	4	18204	49	GAB1,P2RY6,ZFP36L1,CYFIP1
4.653e-02	-3.07	FDFT1 (farnesyl-diphosphate farnesyltransferase 1)	protein interactions	2222	134	2	19454	50	UNC93B1,CD74
4.654e-02	-3.07	nitrogen compound transport	biological process	GO:0071705	1507	8	18204	49	UNC93B1,PSAP,CD74,SNX17,VMP1,CMTM6,PLEK,ZFP36L1
4.674e-02	-3.06	GRB2 (growth factor receptor bound protein 2)	protein interactions	2885	769	5	19454	50	CSF3R,SH2B3,GAB1,INPP5D,CSF1R
4.680e-02	-3.06	ATP5PO (ATP synthase peripheral stalk subunit OSCP)	protein interactions	539	314	3	19454	50	P2RY6,PREX1,UNC93B1
4.683e-02	-3.06	P2Y receptors	REACTOME pathways	R-HSA-417957	12	1	10285	41	P2RY6
4.683e-02	-3.06	Transport of organic anions	REACTOME pathways	R-HSA-879518	12	1	10285	41	SLCO2B1
4.683e-02	-3.06	Pyrimidine catabolism	REACTOME pathways	R-HSA-73621	12	1	10285	41	DPYD
4.683e-02	-3.06	PECAM1 interactions	REACTOME pathways	R-HSA-210990	12	1	10285	41	INPP5D
4.709e-02	-3.06	phagocytic vesicle	cellular component	GO:0045335	141	2	19108	47	RAC2,UNC93B1
4.716e-02	-3.05	SEL1L (SEL1L adaptor subunit of SYVN1 ubiquitin ligase)	protein interactions	6400	135	2	19454	50	UNC93B1,P2RY6
4.720e-02	-3.05	response to organophosphorus	biological process	GO:0046683	129	2	18204	49	ZFP36L1,P2RY6
4.721e-02	-3.05	regulation of cell population proliferation	biological process	GO:0042127	1790	9	18204	49	CD74,ZFP36L1,P2RY6,CSF1R,INPP5D,RAC2,SH2B3,HCK,ITGAX
4.738e-02	-3.05	cell-cell junction maintenance	biological process	GO:0045217	18	1	18204	49	CSF1R
4.738e-02	-3.05	positive regulation of type 2 immune response	biological process	GO:0002830	18	1	18204	49	CD74
4.738e-02	-3.05	regulation of dopamine metabolic process	biological process	GO:0042053	18	1	18204	49	ITGB2
4.738e-02	-3.05	positive regulation of myelination	biological process	GO:0031643	18	1	18204	49	ITGAX
4.738e-02	-3.05	regulation of hydrogen peroxide metabolic process	biological process	GO:0010310	18	1	18204	49	RAC2
4.738e-02	-3.05	ceramide transport	biological process	GO:0035627	18	1	18204	49	PSAP
4.738e-02	-3.05	negative regulation of platelet activation	biological process	GO:0010544	18	1	18204	49	SH2B3
4.738e-02	-3.05	pyrimidine deoxyribonucleotide catabolic process	biological process	GO:0009223	18	1	18204	49	DPYD
4.738e-02	-3.05	positive regulation of superoxide anion generation	biological process	GO:0032930	18	1	18204	49	ITGB2
4.738e-02	-3.05	negative regulation of bone remodeling	biological process	GO:0046851	18	1	18204	49	INPP5D
4.738e-02	-3.05	regulation of catecholamine metabolic process	biological process	GO:0042069	18	1	18204	49	ITGB2
4.752e-02	-3.05	Integrin_alpha	interpro domains	IPR000413	18	1	18521	50	ITGAX
4.752e-02	-3.05	Integrin_alpha_Ig-like_2	interpro domains	IPR048285	18	1	18521	50	ITGAX
4.760e-02	-3.04	positive regulation of kinase activity	biological process	GO:0033674	302	3	18204	49	MAP3K11,CD74,CSF1R
4.774e-02	-3.04	SP6 (Sp6 transcription factor)	protein interactions	80320	19	1	19454	50	RMC1
4.774e-02	-3.04	SPOCK2 (SPARC (osteonectin), cwcv and kazal like domains proteoglycan 2)	protein interactions	9806	19	1	19454	50	SPOCK3
4.774e-02	-3.04	CSF1 (colony stimulating factor 1)	protein interactions	1435	19	1	19454	50	CSF1R
4.774e-02	-3.04	CHAC2 (ChaC glutathione specific gamma-glutamylcyclotransferase 2)	protein interactions	494143	19	1	19454	50	DPYD
4.779e-02	-3.04	ITGB5 (integrin subunit beta 5)	protein interactions	3693	136	2	19454	50	ADAM33,RAC2
4.779e-02	-3.04	FPR2 (formyl peptide receptor 2)	protein interactions	2358	136	2	19454	50	UNC93B1,VMP1
4.786e-02	-3.04	negative regulation of T cell activation	biological process	GO:0050868	130	2	18204	49	TNFAIP8L2,CD74
4.816e-02	-3.03	Complement and coagulation cascades	KEGG pathways	hsa04610	79	2	7161	32	ITGAX,ITGB2
4.816e-02	-3.03	Complement and coagulation cascades	KEGG pathways	ko04610	79	2	7161	32	ITGB2,ITGAX
4.824e-02	-3.03	regulation of apoptotic process	biological process	GO:0042981	1518	8	18204	49	MAP3K11,TNFAIP8L2,HCK,ZFP36L1,CD74,INPP5D,PLXND1,CSF1R
4.828e-02	-3.03	RHOT2 (ras homolog family member T2)	protein interactions	89941	318	3	19454	50	CD74,P2RY6,SMPD4
4.842e-02	-3.03	NCOA6 (nuclear receptor coactivator 6)	protein interactions	23054	137	2	19454	50	RXRA,THRB
4.844e-02	-3.03	ADAM_CR	pfam domains	PF08516	18	1	17795	49	ADAM33
4.844e-02	-3.03	SRCR	pfam domains	PF00530	18	1	17795	49	MARCO
4.844e-02	-3.03	Integrin_A_Ig_2	pfam domains	PF20805	18	1	17795	49	ITGAX
4.852e-02	-3.03	mesoderm development	biological process	GO:0007498	131	2	18204	49	ZFP36L1,HCK
4.855e-02	-3.03	skin-face-other-keratoacanthoma	COSMIC cancer mutations	skin-face-other-keratoacanthoma	19	1	16828	44	CSF1R
4.855e-02	-3.03	skin-back-other-keratoacanthoma	COSMIC cancer mutations	skin-back-other-keratoacanthoma	19	1	16828	44	CSF1R
4.855e-02	-3.03	skin-lower_leg-other-keratoacanthoma	COSMIC cancer mutations	skin-lower_leg-other-keratoacanthoma	19	1	16828	44	CSF1R
4.855e-02	-3.03	skin-upper_leg-other-keratoacanthoma	COSMIC cancer mutations	skin-upper_leg-other-keratoacanthoma	19	1	16828	44	CSF1R
4.855e-02	-3.03	genital	COSMIC cancer mutations	genital	19	1	16828	44	CSF1R
4.855e-02	-3.03	skin-chest-carcinoma-squamous_cell_carcinoma	COSMIC cancer mutations	skin-chest-carcinoma-squamous_cell_carcinoma	19	1	16828	44	CSF1R
4.855e-02	-3.03	skin-arm-other-keratoacanthoma	COSMIC cancer mutations	skin-arm-other-keratoacanthoma	19	1	16828	44	CSF1R
4.855e-02	-3.03	skin-leg-carcinoma-squamous_cell_carcinoma	COSMIC cancer mutations	skin-leg-carcinoma-squamous_cell_carcinoma	19	1	16828	44	CSF1R
4.855e-02	-3.03	skin-lip-other-keratoacanthoma	COSMIC cancer mutations	skin-lip-other-keratoacanthoma	19	1	16828	44	CSF1R
4.855e-02	-3.03	skin-genital-carcinoma-squamous_cell_carcinoma	COSMIC cancer mutations	skin-genital-carcinoma-squamous_cell_carcinoma	19	1	16828	44	CSF1R
4.855e-02	-3.03	skin-upper_arm-carcinoma-squamous_cell_carcinoma	COSMIC cancer mutations	skin-upper_arm-carcinoma-squamous_cell_carcinoma	19	1	16828	44	CSF1R
4.855e-02	-3.03	skin-chest-other-keratoacanthoma	COSMIC cancer mutations	skin-chest-other-keratoacanthoma	19	1	16828	44	CSF1R
4.903e-02	-3.02	positive regulation of cell population proliferation	biological process	GO:0008284	992	6	18204	49	ITGAX,CSF1R,HCK,P2RY6,CD74,RAC2
4.905e-02	-3.01	ZW10 (zw10 kinetochore protein)	protein interactions	9183	138	2	19454	50	RAC2,UNC93B1
4.905e-02	-3.01	AKAP12 (A-kinase anchoring protein 12)	protein interactions	9590	138	2	19454	50	HCK,RAC2
4.905e-02	-3.01	PFN2 (profilin 2)	protein interactions	5217	138	2	19454	50	RAC2,CYFIP1
4.905e-02	-3.01	NCOA1 (nuclear receptor coactivator 1)	protein interactions	8648	138	2	19454	50	THRB,RXRA
4.907e-02	-3.01	Fc Epsilon Receptor I Signaling in Mast Cells	SMPDB pathways	SMP0000358	34	1	1369	2	INPP5D
4.912e-02	-3.01	1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)	BIOCYC pathways	HUMAN_PWY-6362	15	1	902	3	INPP5D
4.912e-02	-3.01	1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)	BIOCYC pathways	META_PWY-6362	15	1	902	3	INPP5D
4.912e-02	-3.01	D-myo-inositol (1,3,4)-trisphosphate biosynthesis	BIOCYC pathways	META_PWY-6364	15	1	902	3	INPP5D
4.912e-02	-3.01	D-myo-inositol (1,3,4)-trisphosphate biosynthesis	BIOCYC pathways	HUMAN_PWY-6364	15	1	902	3	INPP5D
4.916e-02	-3.01	regulation of small GTPase mediated signal transduction	biological process	GO:0051056	306	3	18204	49	PREX1,DOCK2,ABR
4.918e-02	-3.01	regulation of mRNA processing	biological process	GO:0050684	132	2	18204	49	ZFP36L1,RBM47
4.937e-02	-3.01	positive regulation of cellular component biogenesis	biological process	GO:0044089	515	4	18204	49	PLEK,CYFIP1,RAC2,HCK
4.940e-02	-3.01	T-Cell antigen Receptor (TCR) Signaling Pathway	WikiPathways	WP69	91	2	5310	21	SH2B3,FYB1
4.957e-02	-3.00	PDGFR-beta signaling pathway	Pathway Interaction DB	pdgfrbpathway	54	2	2226	15	HCK,GAB1
4.968e-02	-3.00	MON2 (MON2 homolog, regulator of endosome-to-Golgi trafficking)	protein interactions	23041	139	2	19454	50	UNC93B1,P2RY6
4.968e-02	-3.00	PTPRA (protein tyrosine phosphatase receptor type A)	protein interactions	5786	139	2	19454	50	GAB1,CYFIP1
4.968e-02	-3.00	STX18 (syntaxin 18)	protein interactions	53407	139	2	19454	50	RAC2,DPYD
4.968e-02	-3.00	TMEM131 (transmembrane protein 131)	protein interactions	23505	139	2	19454	50	ADAM33,RAC2
4.982e-02	-3.00	Sphingolipid metabolism	REACTOME pathways	R-HSA-428157	90	2	10285	41	SMPD4,PSAP
4.985e-02	-3.00	nucleoside phosphate catabolic process	biological process	GO:1901292	133	2	18204	49	DPYD,ENTPD1
4.995e-02	-3.00	3'-UTR-mediated mRNA destabilization	biological process	GO:0061158	19	1	18204	49	ZFP36L1
4.995e-02	-3.00	lipoprotein transport	biological process	GO:0042953	19	1	18204	49	VMP1
4.995e-02	-3.00	regulation of B cell apoptotic process	biological process	GO:0002902	19	1	18204	49	CD74
4.995e-02	-3.00	negative regulation of amyloid precursor protein biosynthetic process	biological process	GO:0042985	19	1	18204	49	ITM2B
4.995e-02	-3.00	negative regulation of alcohol biosynthetic process	biological process	GO:1902931	19	1	18204	49	PLEK
4.995e-02	-3.00	sphingomyelin metabolic process	biological process	GO:0006684	19	1	18204	49	SMPD4
4.995e-02	-3.00	base conversion or substitution editing	biological process	GO:0016553	19	1	18204	49	RBM47
4.995e-02	-3.00	positive regulation of macrophage chemotaxis	biological process	GO:0010759	19	1	18204	49	CSF1R
4.995e-02	-3.00	positive regulation of protein depolymerization	biological process	GO:1901881	19	1	18204	49	PLEK
4.995e-02	-3.00	nucleoside monophosphate catabolic process	biological process	GO:0009125	19	1	18204	49	DPYD