TermID Term Enrichment logP Genes in Term Target Genes in Term Fraction of Targets in Term Total Target Genes Total Genes Entrez Gene IDs Gene Symbols WP69 T-Cell antigen Receptor (TCR) Signaling Pathway 6.55189020824922e-05 -9.63317187554258 91 5 0.192307692307692 26 5310 2533,5580,7454,10451,8631 FYB1,PRKCD,WAS,VAV3,SKAP1 WP1449 Regulation of toll-like receptor signaling pathway 0.000586459092331323 -7.441407641099 145 5 0.192307692307692 26 5310 5291,3663,5777,23533,6850 PIK3CB,IRF5,PTPN6,PIK3R5,SYK WP23 B Cell Receptor Signaling Pathway 0.00119405964198126 -6.73039631385116 98 4 0.153846153846154 26 5310 5777,6850,5336,5580 PTPN6,SYK,PLCG2,PRKCD WP80 Nucleotide GPCRs 0.00123418520198696 -6.69734428211276 11 2 0.0769230769230769 26 5310 5029,5031 P2RY2,P2RY6 WP1584 Type II diabetes mellitus 0.00501483052197378 -5.29535565236185 22 2 0.0769230769230769 26 5310 23533,5580 PIK3R5,PRKCD WP51 Regulation of Actin Cytoskeleton 0.00550161651239164 -5.20271331858326 149 4 0.153846153846154 26 5310 5291,1793,23533,7454 PIK3CB,DOCK1,PIK3R5,WAS WP289 Myometrial Relaxation and Contraction Pathways 0.0067668721591871 -4.99571631371084 158 4 0.153846153846154 26 5310 5580,113,10636,5336 PRKCD,ADCY7,RGS14,PLCG2 WP2261 Signaling Pathways in Glioblastoma 0.00738802600417409 -4.907894696866 83 3 0.115384615384615 26 5310 5580,5336,5291 PRKCD,PLCG2,PIK3CB WP35 G Protein Signaling Pathways 0.0107061421060303 -4.53693767360471 95 3 0.115384615384615 26 5310 5580,11214,113 PRKCD,AKAP13,ADCY7 WP185 Integrin-mediated Cell Adhesion 0.0133300757366374 -4.31773246313944 103 3 0.115384615384615 26 5310 9815,10451,1793 GIT2,VAV3,DOCK1 WP75 Toll-like Receptor Signaling Pathway 0.0133300757366374 -4.31773246313944 103 3 0.115384615384615 26 5310 5291,3663,23533 PIK3CB,IRF5,PIK3R5 WP524 G13 Signaling Pathway 0.0160436518145698 -4.13244203321895 40 2 0.0769230769230769 26 5310 7454,5291 WAS,PIK3CB WP364 IL-6 signaling pathway 0.0184077545506139 -3.9949832601812 43 2 0.0769230769230769 26 5310 5580,3570 PRKCD,IL6R WP2848 Differentiation Pathway 0.0226535492560582 -3.78743873928255 48 2 0.0769230769230769 26 5310 1436,3570 CSF1R,IL6R WP286 IL-3 Signaling Pathway 0.0235471475069636 -3.74875059082563 49 2 0.0769230769230769 26 5310 5777,6850 PTPN6,SYK WP3646 Hepatitis C and Hepatocellular Carcinoma 0.0253775583955138 -3.673890023234 51 2 0.0769230769230769 26 5310 3570,3091 IL6R,HIF1A WP2864 Apoptosis-related network due to altered Notch3 in ovarian cancer 0.0282289568972946 -3.56740698754838 54 2 0.0769230769230769 26 5310 10451,348 VAV3,APOE WP536 Calcium Regulation in the Cardiac Cell 0.0363219494681652 -3.3153330519052 151 3 0.115384615384615 26 5310 113,10636,5580 ADCY7,RGS14,PRKCD WP2324 AGE/RAGE pathway 0.0408296345967476 -3.19834712307234 66 2 0.0769230769230769 26 5310 5580,3091 PRKCD,HIF1A WP2374 Oncostatin M Signaling Pathway 0.0408296345967476 -3.19834712307234 66 2 0.0769230769230769 26 5310 5580,3091 PRKCD,HIF1A WP481 Insulin Signaling 0.0426883938005575 -3.15382820364351 161 3 0.115384615384615 26 5310 115703,5580,5291 ARHGAP33,PRKCD,PIK3CB WP3593 miR-148a/miR-31/FIH1/HIF1α-Notch signaling in glioblastoma 0.0432464387977855 -3.14084038892996 9 1 0.0384615384615385 26 5310 3091 HIF1A WP3601 Composition of Lipid Particles 0.0479390614333288 -3.0378246281123 10 1 0.0384615384615385 26 5310 348 APOE WP3630 NAD metabolism, sirtuins and aging 0.0526095490577176 -2.9448576346938 11 1 0.0384615384615385 26 5310 3091 HIF1A WP2037 Prolactin Signaling Pathway 0.0526633832848754 -2.94383487925891 76 2 0.0769230769230769 26 5310 5777,5291 PTPN6,PIK3CB WP3672 LncRNA-mediated mechanisms of therapeutic resistance 0.0572580019204122 -2.86018787477934 12 1 0.0384615384615385 26 5310 3091 HIF1A WP306 Focal Adhesion 0.0682434030551801 -2.68467450812097 195 3 0.115384615384615 26 5310 23533,1793,5291 PIK3R5,DOCK1,PIK3CB WP2355 Corticotropin-releasing hormone signaling pathway 0.0751766215757931 -2.5879149796612 93 2 0.0769230769230769 26 5310 5336,5580 PLCG2,PRKCD WP3644 NAD+ metabolism 0.075633455644179 -2.58185655871046 16 1 0.0384615384615385 26 5310 203447 NRK WP615 Senescence and Autophagy in Cancer 0.0941218794503579 -2.36316474666151 106 2 0.0769230769230769 26 5310 3663,3570 IRF5,IL6R WP167 Eicosanoid Synthesis 0.102552365559983 -2.2773817273482 22 1 0.0384615384615385 26 5310 6916 TBXAS1 WP710 DNA Damage Response (only ATM dependent) 0.106410430146277 -2.24045167918842 114 2 0.0769230769230769 26 5310 5291,23533 PIK3CB,PIK3R5 WP1539 Angiogenesis 0.111356628422636 -2.19501735923156 24 1 0.0384615384615385 26 5310 3091 HIF1A WP2583 T-Cell Receptor and Co-stimulatory Signaling 0.133005446581002 -2.01736519986203 29 1 0.0384615384615385 26 5310 5777 PTPN6 WP3844 PI3K-AKT-mTOR signaling pathway and therapeutic opportunities 0.137273929519265 -1.98577686392253 30 1 0.0384615384615385 26 5310 5291 PIK3CB WP2870 Extracellular vesicle-mediated signaling in recipient cells 0.137273929519265 -1.98577686392253 30 1 0.0384615384615385 26 5310 23533 PIK3R5 WP98 Prostaglandin Synthesis and Regulation 0.137273929519265 -1.98577686392253 30 1 0.0384615384615385 26 5310 6916 TBXAS1 WP430 Statin Pathway 0.14995848174425 -1.89739681157052 33 1 0.0384615384615385 26 5310 348 APOE WP313 Signaling of Hepatocyte Growth Factor Receptor 0.154146671904025 -1.86985071486667 34 1 0.0384615384615385 26 5310 1793 DOCK1 WP2380 Brain-Derived Neurotrophic Factor (BDNF) signaling pathway 0.155842706718551 -1.85890807066488 144 2 0.0769230769230769 26 5310 5580,10451 PRKCD,VAV3 WP244 Alpha 6 Beta 4 signaling pathway 0.158315016583945 -1.84316845504058 35 1 0.0384615384615385 26 5310 5580 PRKCD WP3298 Melatonin metabolism and effects 0.162463606074294 -1.81730126491545 36 1 0.0384615384615385 26 5310 348 APOE WP2012 miRs in Muscle Cell Differentiation 0.162463606074294 -1.81730126491545 36 1 0.0384615384615385 26 5310 5580 PRKCD WP619 Type II interferon signaling (IFNG) 0.166592530277481 -1.79220438652419 37 1 0.0384615384615385 26 5310 5580 PRKCD WP3614 Photodynamic therapy-induced HIF-1 survival signaling 0.166592530277481 -1.79220438652419 37 1 0.0384615384615385 26 5310 3091 HIF1A WP127 IL-5 Signaling Pathway 0.178862204259508 -1.72113957820228 40 1 0.0384615384615385 26 5310 6850 SYK WP49 IL-2 Signaling Pathway 0.186945291033458 -1.67693926625037 42 1 0.0384615384615385 26 5310 6850 SYK WP437 EGF/EGFR Signaling Pathway 0.187365579459377 -1.6746936002242 162 2 0.0769230769230769 26 5310 10451,5580 VAV3,PRKCD WP706 Sudden Infant Death Syndrome (SIDS) Susceptibility Pathways 0.187365579459377 -1.6746936002242 162 2 0.0769230769230769 26 5310 3091,3570 HIF1A,IL6R WP1533 Vitamin B12 Metabolism 0.230052694259279 -1.46944689082447 53 1 0.0384615384615385 26 5310 348 APOE WP673 ErbB Signaling Pathway 0.233860689302358 -1.45302968577428 54 1 0.0384615384615385 26 5310 23533 PIK3R5 WP2018 RANKL/RANK (Receptor activator of NFKB (ligand)) Signaling Pathway 0.237650571738097 -1.43695387012616 55 1 0.0384615384615385 26 5310 6850 SYK WP585 Interferon type I signaling pathways 0.237650571738097 -1.43695387012616 55 1 0.0384615384615385 26 5310 5777 PTPN6 WP2272 Pathogenic Escherichia coli infection 0.237650571738097 -1.43695387012616 55 1 0.0384615384615385 26 5310 7454 WAS WP395 IL-4 Signaling Pathway 0.237650571738097 -1.43695387012616 55 1 0.0384615384615385 26 5310 5777 PTPN6 WP304 Kit receptor signaling pathway 0.256331177385007 -1.36128500890166 60 1 0.0384615384615385 26 5310 5777 PTPN6 WP3863 T-Cell antigen Receptor (TCR) pathway during Staphylococcus aureus infection 0.263679498901975 -1.33302093266493 62 1 0.0384615384615385 26 5310 5777 PTPN6 WP61 Notch Signaling Pathway 0.263679498901975 -1.33302093266493 62 1 0.0384615384615385 26 5310 3091 HIF1A WP1403 AMP-activated Protein Kinase (AMPK) Signaling 0.28530794452796 -1.2541861749255 68 1 0.0384615384615385 26 5310 5291 PIK3CB WP428 Wnt Signaling Pathway 0.292380693330827 -1.22969858156682 70 1 0.0384615384615385 26 5310 5580 PRKCD WP2034 Leptin signaling pathway 0.313197434034684 -1.16092150763633 76 1 0.0384615384615385 26 5310 5336 PLCG2 WP254 Apoptosis 0.346589937762663 -1.05961293338961 86 1 0.0384615384615385 26 5310 3663 IRF5 WP455 GPCRs, Class A Rhodopsin-like 0.364418306955205 -1.00945287623255 259 2 0.0769230769230769 26 5310 5031,5029 P2RY6,P2RY2 WP1544 MicroRNAs in cardiomyocyte hypertrophy 0.396794171236175 -0.924337593104273 102 1 0.0384615384615385 26 5310 5291 PIK3CB WP179 Cell Cycle 0.405785051361853 -0.901931689721247 105 1 0.0384615384615385 26 5310 11138 TBC1D8 WP399 Wnt Signaling Pathway and Pluripotency 0.408753272047378 -0.894643551793839 106 1 0.0384615384615385 26 5310 5580 PRKCD WP236 Adipogenesis 0.478491254525782 -0.737117345109272 131 1 0.0384615384615385 26 5310 3091 HIF1A WP3915 Angiopoietin Like Protein 8 Regulatory Pathway 0.481109371417138 -0.731660651320451 132 1 0.0384615384615385 26 5310 5291 PIK3CB WP2853 Endoderm Differentiation 0.514015670315598 -0.665501526996365 145 1 0.0384615384615385 26 5310 10451 VAV3 WP2059 Alzheimers Disease 0.521319358105851 -0.651392453606628 148 1 0.0384615384615385 26 5310 348 APOE WP2857 Mesodermal Commitment Pathway 0.537953146454432 -0.619983810987427 155 1 0.0384615384615385 26 5310 10451 VAV3 WP382 MAPK Signaling Pathway 0.571745897252059 -0.559060621877516 170 1 0.0384615384615385 26 5310 5580 PRKCD WP3876 BMP2-WNT4-FOXO1 Pathway in Human Primary Endometrial Stromal Cell Differentiation 0.999999999987221 -1.27788603454933e-11 13 0 0 26 5310 WP3679 Cell-type Dependent Selectivity of CCK2R Signaling 0.999999999987221 -1.27788603454933e-11 13 0 0 26 5310 WP1434 Osteopontin Signaling 0.999999999987221 -1.27788603454933e-11 13 0 0 26 5310 WP1991 SRF and miRs in Smooth Muscle Differentiation and Proliferation 0.999999999987221 -1.27788603454933e-11 13 0 0 26 5310 WP2881 Estrogen Receptor Pathway 0.999999999987221 -1.27788603454933e-11 13 0 0 26 5310 WP1423 Ganglio Sphingolipid Metabolism 0.999999999987221 -1.27788603454933e-11 13 0 0 26 5310 WP186 Homologous recombination 0.999999999987221 -1.27788603454933e-11 13 0 0 26 5310 WP3871 Valproic acid pathway 0.999999999987221 -1.27788603454933e-11 13 0 0 26 5310 WP3892 Development of pulmonary dendritic cells and macrophage subsets 0.999999999987221 -1.27788603454933e-11 13 0 0 26 5310 WP500 Glycogen Metabolism 0.999999999987254 -1.27456951284432e-11 36 0 0 26 5310 WP2359 Parkin-Ubiquitin Proteasomal System pathway 0.999999999990014 -9.986462628682e-12 70 0 0 26 5310 WP383 Striated Muscle Contraction 0.999999999990405 -9.59536820914815e-12 38 0 0 26 5310 WP2447 Amyotrophic lateral sclerosis (ALS) 0.999999999990405 -9.59536820914815e-12 38 0 0 26 5310 WP2526 PDGF Pathway 0.999999999990405 -9.59536820914815e-12 38 0 0 26 5310 WP2029 Cell Differentiation - Index 0.999999999990405 -9.59536820914815e-12 38 0 0 26 5310 WP2267 Synaptic Vesicle Pathway 0.999999999990702 -9.29800686782471e-12 52 0 0 26 5310 WP107 Translation Factors 0.999999999991178 -8.82168556007081e-12 53 0 0 26 5310 WP363 Wnt Signaling Pathway Netpath 0.999999999991178 -8.82168556007081e-12 53 0 0 26 5310 WP2406 Cardiac Progenitor Differentiation 0.999999999991178 -8.82168556007081e-12 53 0 0 26 5310 WP3635 Insulin signalling in human adipocytes (diabetic condition) 0.999999999991208 -8.79235315296053e-12 8 0 0 26 5310 WP3634 Insulin signalling in human adipocytes (normal condition) 0.999999999991208 -8.79235315296053e-12 8 0 0 26 5310 WP1589 Folate-Alcohol and Cancer Pathway 0.999999999991208 -8.79235315296053e-12 8 0 0 26 5310 WP3655 Hypothetical Craniofacial Development Pathway 0.999999999991208 -8.79235315296053e-12 8 0 0 26 5310 WP136 Phase I biotransformations, non P450 0.999999999991208 -8.79235315296053e-12 8 0 0 26 5310 WP237 Glucocorticoid & Mineralcorticoid Metabolism 0.999999999991208 -8.79235315296053e-12 8 0 0 26 5310 WP2276 Glial Cell Differentiation 0.999999999991208 -8.79235315296053e-12 8 0 0 26 5310 WP3407 FTO Obesity Variant Mechanism 0.999999999991208 -8.79235315296053e-12 8 0 0 26 5310 WP1604 Codeine and Morphine Metabolism 0.999999999991208 -8.79235315296053e-12 8 0 0 26 5310 WP2485 NAD Biosynthesis II (from tryptophan) 0.999999999991208 -8.79235315296053e-12 8 0 0 26 5310 WP2338 miRNA Biogenesis 0.999999999991208 -8.79235315296053e-12 8 0 0 26 5310 WP2942 DDX1 as a regulatory component of the Drosha microprocessor 0.999999999992374 -7.62635806979578e-12 9 0 0 26 5310 WP3674 Tgif disruption of Shh signaling 0.999999999992374 -7.62635806979578e-12 9 0 0 26 5310 WP3300 Dual hijack model of Vif in HIV infection 0.999999999992374 -7.62635806979578e-12 9 0 0 26 5310 WP3585 Cytosine methylation 0.999999999992374 -7.62635806979578e-12 9 0 0 26 5310 WP696 Benzo(a)pyrene metabolism 0.999999999992374 -7.62635806979578e-12 9 0 0 26 5310 WP3297 EV release from cardiac cells and their functional effects 0.999999999992374 -7.62635806979578e-12 9 0 0 26 5310 WP561 Heme Biosynthesis 0.999999999992374 -7.62635806979578e-12 9 0 0 26 5310 WP3875 ATR Signaling 0.999999999992374 -7.62635806979578e-12 9 0 0 26 5310 WP288 NLR Proteins 0.999999999992374 -7.62635806979578e-12 9 0 0 26 5310 WP531 Mismatch repair 0.999999999992374 -7.62635806979578e-12 9 0 0 26 5310 WP1422 Sphingolipid Metabolism 0.999999999993622 -6.37794941422421e-12 20 0 0 26 5310 WP391 Mitochondrial Gene Expression 0.999999999993622 -6.37794941422421e-12 20 0 0 26 5310 WP732 Serotonin Receptor 2 and ELK-SRF/GATA4 signaling 0.999999999993622 -6.37794941422421e-12 20 0 0 26 5310 WP516 Hypertrophy Model 0.999999999993622 -6.37794941422421e-12 20 0 0 26 5310 WP497 Urea cycle and metabolism of amino groups 0.999999999993622 -6.37794941422421e-12 20 0 0 26 5310 WP1742 TP53 Network 0.999999999993622 -6.37794941422421e-12 20 0 0 26 5310 WP2249 Metastatic brain tumor 0.999999999993682 -6.3180994874008e-12 28 0 0 26 5310 WP2361 Gastric Cancer Network 1 0.999999999993682 -6.3180994874008e-12 28 0 0 26 5310 WP2369 Histone Modifications 0.999999999993759 -6.24071161089993e-12 69 0 0 26 5310 WP707 DNA Damage Response 0.999999999993759 -6.24071161089993e-12 69 0 0 26 5310 WP176 Folate Metabolism 0.999999999993759 -6.24071161089993e-12 69 0 0 26 5310 WP2637 Structural Pathway of Interleukin 1 (IL-1) 0.99999999999387 -6.13017587420835e-12 50 0 0 26 5310 WP1545 miRNAs involved in DNA damage response 0.99999999999387 -6.13017587420835e-12 50 0 0 26 5310 WP688 Catalytic cycle of mammalian Flavin-containing MonoOxygenases (FMOs) 0.999999999993948 -6.05189879657161e-12 5 0 0 26 5310 WP3596 miR-517 relationship with ARCN1 and USP1 0.999999999993948 -6.05189879657161e-12 5 0 0 26 5310 WP2597 Secretion of Hydrochloric Acid in Parietal Cells 0.999999999993948 -6.05189879657161e-12 5 0 0 26 5310 WP311 Synthesis and Degradation of Ketone Bodies 0.999999999993948 -6.05189879657161e-12 5 0 0 26 5310 WP2542 Sulindac Metabolic Pathway 0.999999999993948 -6.05189879657161e-12 5 0 0 26 5310 WP2868 TCA Cycle Nutrient Utilization and Invasiveness of Ovarian Cancer 0.999999999993948 -6.05189879657161e-12 5 0 0 26 5310 WP2636 Common Pathways Underlying Drug Addiction 0.999999999994822 -5.17756901803284e-12 42 0 0 26 5310 WP405 Eukaryotic Transcription Initiation 0.999999999994822 -5.17756901803284e-12 42 0 0 26 5310 WP466 DNA Replication 0.999999999994822 -5.17756901803284e-12 42 0 0 26 5310 WP2036 TNF related weak inducer of apoptosis (TWEAK) Signaling Pathway 0.999999999994822 -5.17756901803284e-12 42 0 0 26 5310 WP560 TGF-beta Receptor Signaling 0.999999999995097 -4.90324327466413e-12 58 0 0 26 5310 WP2203 Thymic Stromal LymphoPoietin (TSLP) Signaling Pathway 0.9999999999952 -4.8002735423696e-12 47 0 0 26 5310 WP2795 Cardiac Hypertrophic Response 0.999999999995481 -4.51877642307178e-12 57 0 0 26 5310 WP195 IL-1 signaling pathway 0.999999999995481 -4.51877642307178e-12 57 0 0 26 5310 WP2879 Farnesoid X Receptor Pathway 0.999999999995596 -4.40423617434279e-12 19 0 0 26 5310 WP3287 Overview of nanoparticle effects 0.999999999995596 -4.40423617434279e-12 19 0 0 26 5310 WP22 IL-9 Signaling Pathway 0.999999999995596 -4.40423617434279e-12 19 0 0 26 5310 WP247 Small Ligand GPCRs 0.999999999995596 -4.40423617434279e-12 19 0 0 26 5310 WP734 Serotonin Receptor 4/6/7 and NR3C Signaling 0.999999999995596 -4.40423617434279e-12 19 0 0 26 5310 WP697 Estrogen metabolism 0.999999999995596 -4.40423617434279e-12 19 0 0 26 5310 WP2011 SREBF and miR33 in cholesterol and lipid homeostasis 0.999999999995596 -4.40423617434279e-12 19 0 0 26 5310 WP3877 Simplified Depiction of MYD88 Distinct Input-Output Pathway 0.999999999995596 -4.40423617434279e-12 19 0 0 26 5310 WP404 Nucleotide Metabolism 0.999999999995596 -4.40423617434279e-12 19 0 0 26 5310 WP384 Apoptosis Modulation by HSP70 0.999999999995596 -4.40423617434279e-12 19 0 0 26 5310 WP1992 TarBasePathway 0.999999999995596 -4.40423617434279e-12 19 0 0 26 5310 WP2035 Follicle Stimulating Hormone (FSH) signaling pathway 0.999999999995885 -4.11493181723184e-12 27 0 0 26 5310 WP3845 Canonical and Non-canonical Notch signaling 0.999999999995885 -4.11493181723184e-12 27 0 0 26 5310 WP2572 Primary Focal Segmental Glomerulosclerosis FSGS 0.999999999996492 -3.50804843081262e-12 74 0 0 26 5310 WP24 Peptide GPCRs 0.999999999996492 -3.50804843081262e-12 74 0 0 26 5310 WP117 GPCRs, Other 0.999999999996719 -3.28101457640577e-12 95 0 0 26 5310 WP2586 Aryl Hydrocarbon Receptor 0.999999999997193 -2.80717553431748e-12 48 0 0 26 5310 WP2849 Hematopoietic Stem Cell Differentiation 0.999999999997193 -2.80717553431748e-12 48 0 0 26 5310 WP2873 Aryl Hydrocarbon Receptor Pathway 0.999999999997193 -2.80717553431748e-12 48 0 0 26 5310 WP2846 Proprotein convertase subtilisin/kexin type 9 (PCSK9) mediated LDL receptor degradation 0.99999999999735 -2.65002601766686e-12 3 0 0 26 5310 WP3408 Evolocumab Mechanism 0.99999999999735 -2.65002601766686e-12 3 0 0 26 5310 WP2371 Parkinsons Disease Pathway 0.999999999997383 -2.61682169500628e-12 83 0 0 26 5310 WP3658 Wnt/beta-catenin Signaling Pathway in Leukemia 0.999999999997496 -2.50357681063914e-12 24 0 0 26 5310 WP334 GPCRs, Class B Secretin-like 0.999999999997496 -2.50357681063914e-12 24 0 0 26 5310 WP2509 Nanoparticle triggered autophagic cell death 0.999999999997496 -2.50357681063914e-12 24 0 0 26 5310 WP262 EBV LMP1 signaling 0.999999999997496 -2.50357681063914e-12 24 0 0 26 5310 WP3302 eIF5A regulation in response to inhibition of the nuclear export system 0.999999999997921 -2.07861549185601e-12 4 0 0 26 5310 WP1941 Peroxisomal beta-oxidation of tetracosanoyl-CoA 0.999999999997921 -2.07861549185601e-12 4 0 0 26 5310 WP2253 Pilocytic astrocytoma 0.999999999997921 -2.07861549185601e-12 4 0 0 26 5310 WP897 Androgen receptor signaling pathway 0.999999999997921 -2.07861549185601e-12 4 0 0 26 5310 WP1603 Nicotine Activity on Chromaffin Cells 0.999999999997921 -2.07861549185601e-12 4 0 0 26 5310 WP2491 Diclofenac Metabolic Pathway 0.999999999997921 -2.07861549185601e-12 4 0 0 26 5310 WP2889 Oxytocin signaling 0.999999999997921 -2.07861549185601e-12 4 0 0 26 5310 WP1133 Androgen receptor signaling pathway 0.999999999997921 -2.07861549185601e-12 4 0 0 26 5310 WP690 Polyol Pathway 0.999999999997921 -2.07861549185601e-12 4 0 0 26 5310 WP733 Serotonin Receptor 2 and STAT3 Signaling 0.999999999997921 -2.07861549185601e-12 4 0 0 26 5310 WP3633 Caffeine and Theobromine metabolism 0.999999999997921 -2.07861549185601e-12 4 0 0 26 5310 WP521 Amino acid conjugation of benzoic acid 0.999999999997921 -2.07861549185601e-12 4 0 0 26 5310 WP3865 RIG-I-like Receptor Signaling 0.999999999997942 -2.05766171917139e-12 61 0 0 26 5310 WP3611 Photodynamic therapy-induced AP-1 survival signaling. 0.999999999998004 -1.99633819729771e-12 51 0 0 26 5310 WP2328 Allograft Rejection 0.999999999998035 -1.96546067014785e-12 80 0 0 26 5310 WP698 Glucuronidation 0.999999999998101 -1.89901295494581e-12 26 0 0 26 5310 WP2878 PPAR Alpha Pathway 0.999999999998101 -1.89901295494581e-12 26 0 0 26 5310 WP581 EPO Receptor Signaling 0.999999999998101 -1.89901295494581e-12 26 0 0 26 5310 WP26 Signal Transduction of S1P Receptor 0.999999999998101 -1.89901295494581e-12 26 0 0 26 5310 WP530 Cytokines and Inflammatory Response 0.999999999998101 -1.89901295494581e-12 26 0 0 26 5310 WP325 Triacylglyceride Synthesis 0.999999999998101 -1.89901295494581e-12 26 0 0 26 5310 WP143 Fatty Acid Beta Oxidation 0.999999999998208 -1.79171656952207e-12 34 0 0 26 5310 WP400 p38 MAPK Signaling Pathway 0.999999999998208 -1.79171656952207e-12 34 0 0 26 5310 WP1601 Fluoropyrimidine Activity 0.999999999998208 -1.79171656952207e-12 34 0 0 26 5310 WP3624 Lung fibrosis 0.999999999998247 -1.75351438243738e-12 63 0 0 26 5310 WP43 Oxidation by Cytochrome P450 0.999999999998247 -1.75351438243738e-12 63 0 0 26 5310 WP3678 Amplification and Expansion of Oncogenic Pathways as Metastatic Traits 0.999999999998449 -1.55143861654228e-12 17 0 0 26 5310 WP554 ACE Inhibitor Pathway 0.999999999998449 -1.55143861654228e-12 17 0 0 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26 5310 WP2516 ATM Signaling Pathway 1.00000000000245 2.45029223272446e-12 40 0 0 26 5310 WP2377 Integrated Pancreatic Cancer Pathway 1.00000000000278 2.78474092926675e-12 197 0 0 26 5310 WP170 Nuclear Receptors 1.00000000000292 2.92464765107516e-12 39 0 0 26 5310 WP2431 Spinal Cord Injury 1.00000000000296 2.96054599004431e-12 119 0 0 26 5310 WP206 Fatty Acid Omega Oxidation 1.00000000000319 3.1864538745471e-12 15 0 0 26 5310 WP197 Cholesterol Biosynthesis 1.00000000000319 3.1864538745471e-12 15 0 0 26 5310 WP3 Transcriptional activation by NRF2 1.00000000000319 3.1864538745471e-12 15 0 0 26 5310 WP2435 Quercetin and Nf-kB/ AP-1 Induced Cell Apoptosis 1.00000000000319 3.1864538745471e-12 15 0 0 26 5310 WP268 Notch Signaling Pathway 1.00000000000355 3.55188324641747e-12 46 0 0 26 5310 WP465 Tryptophan metabolism 1.00000000000355 3.55188324641747e-12 46 0 0 26 5310 WP3878 ATM Signaling Network in Development and Disease 1.00000000000355 3.55188324641747e-12 46 0 0 26 5310 WP28 Selenium Metabolism and Selenoproteins 1.00000000000355 3.55188324641747e-12 46 0 0 26 5310 WP1971 Integrated Cancer Pathway 1.00000000000355 3.55188324641747e-12 46 0 0 26 5310 WP1591 Heart Development 1.00000000000355 3.55188324641747e-12 46 0 0 26 5310 WP1455 Serotonin Transporter Activity 1.00000000000372 3.72394059960469e-12 11 0 0 26 5310 WP2854 Gene regulatory network modelling somitogenesis 1.00000000000372 3.72394059960469e-12 11 0 0 26 5310 WP2513 Nanoparticle triggered regulated necrosis 1.00000000000372 3.72394059960469e-12 11 0 0 26 5310 WP3414 Initiation of transcription and translation elongation at the HIV-1 LTR 1.00000000000427 4.27333231410951e-12 37 0 0 26 5310 WP1471 Target Of Rapamycin (TOR) Signaling 1.00000000000427 4.27333231410951e-12 37 0 0 26 5310 WP3529 Zinc homeostasis 1.00000000000427 4.27333231410951e-12 37 0 0 26 5310 WP1531 Vitamin D Metabolism 1.00000000000453 4.53150140328028e-12 10 0 0 26 5310 WP2333 Trans-sulfuration pathway 1.00000000000453 4.53150140328028e-12 10 0 0 26 5310 WP2113 Type III interferon signaling 1.00000000000453 4.53150140328028e-12 10 0 0 26 5310 WP2874 Liver X Receptor Pathway 1.00000000000453 4.53150140328028e-12 10 0 0 26 5310 WP3656 Interleukin-1 Induced Activation of NF-kappa-B 1.00000000000453 4.53150140328028e-12 10 0 0 26 5310 WP496 Steroid Biosynthesis 1.00000000000453 4.53150140328028e-12 10 0 0 26 5310 WP704 Methylation Pathways 1.00000000000453 4.53150140328028e-12 10 0 0 26 5310 WP716 Vitamin A and Carotenoid Metabolism 1.00000000000467 4.66960638368712e-12 44 0 0 26 5310 WP2332 Interleukin-11 Signaling Pathway 1.00000000000467 4.66960638368712e-12 44 0 0 26 5310 WP314 Fas Ligand (FasL) pathway and Stress induction of Heat Shock Proteins (HSP) regulation 1.00000000000467 4.66960638368712e-12 44 0 0 26 5310 WP3303 Rac1/Pak1/p38/MMP-2 pathway 1.00000000000484 4.83877132337278e-12 68 0 0 26 5310 WP2032 Human Thyroid Stimulating Hormone (TSH) signaling pathway 1.00000000000484 4.83877132337278e-12 68 0 0 26 5310 WP3680 Association Between Physico-Chemical Features and Toxicity Associated Pathways 1.00000000000484 4.83877132337278e-12 68 0 0 26 5310 WP45 G1 to S cell cycle control 1.00000000000484 4.83877132337278e-12 68 0 0 26 5310 WP1984 Integrated Breast Cancer Pathway 1.00000000000485 4.84951997710275e-12 154 0 0 26 5310 WP691 Tamoxifen metabolism 1.00000000000497 4.97412006103265e-12 21 0 0 26 5310 WP1602 Nicotine Activity on Dopaminergic Neurons 1.00000000000497 4.97412006103265e-12 21 0 0 26 5310 WP2533 Glycerophospholipid Biosynthetic Pathway 1.00000000000497 4.97412006103265e-12 21 0 0 26 5310 WP2507 Nanomaterial induced apoptosis 1.00000000000497 4.97412006103265e-12 21 0 0 26 5310 WP3670 Simplified Interaction Map Between LOXL4 and Oxidative Stress Pathway 1.00000000000497 4.97412006103265e-12 21 0 0 26 5310 WP1311 Folic Acid Network 1.00000000000524 5.23547068735251e-12 2 0 0 26 5310 WP1438 Influenza A virus infection 1.00000000000524 5.23547068735251e-12 2 0 0 26 5310 WP2943 Hypoxia-mediated EMT and Stemness 1.00000000000524 5.23547068735251e-12 2 0 0 26 5310 WP2866 mir34a and TGIF2 in osteoclastogenesis 1.00000000000524 5.23547068735251e-12 2 0 0 26 5310 WP2366 Butyrate-induced histone acetylation 1.00000000000524 5.23547068735251e-12 2 0 0 26 5310 WP2646 Lidocaine metabolism 1.00000000000524 5.23547068735251e-12 2 0 0 26 5310 WP2901 Gonadotropin-releasing hormone (GnRH) signaling 1.00000000000524 5.23547068735251e-12 2 0 0 26 5310 WP1273 Folic Acid Network 1.00000000000524 5.23547068735251e-12 2 0 0 26 5310 WP2816 Felbamate Metabolism 1.00000000000524 5.23547068735251e-12 2 0 0 26 5310 WP3859 TGF-B Signaling in Thyroid Cells for Epithelial-Mesenchymal Transition 1.00000000000531 5.30928702471412e-12 18 0 0 26 5310 WP3879 4-hydroxytamoxifen, Dexamethasone, and Retinoic Acids Regulation of p27 Expression 1.00000000000531 5.30928702471412e-12 18 0 0 26 5310 WP3664 Regulation of Wnt/B-catenin Signaling by Small Molecule Compounds 1.00000000000531 5.30928702471412e-12 18 0 0 26 5310 WP3413 NOTCH1 regulation of human endothelial cell calcification 1.00000000000531 5.30928702471412e-12 18 0 0 26 5310 WP692 Sulfation Biotransformation Reaction 1.00000000000531 5.30928702471412e-12 18 0 0 26 5310 WP408 Oxidative Stress 1.00000000000534 5.33879560149951e-12 31 0 0 26 5310 WP3850 Factors and pathways affecting insulin-like growth factor (IGF1)-Akt signaling 1.00000000000534 5.33879560149951e-12 31 0 0 26 5310 WP2112 IL17 signaling pathway 1.00000000000534 5.33879560149951e-12 31 0 0 26 5310 WP550 Biogenic Amine Synthesis 1.00000000000562 5.61731231208235e-12 16 0 0 26 5310 WP2453 TCA Cycle and Deficiency of Pyruvate Dehydrogenase complex (PDHc) 1.00000000000562 5.61731231208235e-12 16 0 0 26 5310 WP2291 Deregulation of Rab and Rab Effector Genes in Bladder Cancer 1.00000000000562 5.61731231208235e-12 16 0 0 26 5310 WP501 GPCRs, Class C Metabotropic glutamate, pheromone 1.00000000000562 5.61731231208235e-12 16 0 0 26 5310 WP47 Hedgehog Signaling Pathway 1.00000000000562 5.61731231208235e-12 16 0 0 26 5310 WP1946 Cori Cycle 1.00000000000562 5.61731231208235e-12 16 0 0 26 5310 WP53 ID signaling pathway 1.00000000000562 5.61731231208235e-12 16 0 0 26 5310 WP12 Osteoclast Signaling 1.00000000000562 5.61731231208235e-12 16 0 0 26 5310 WP15 Selenium Micronutrient Network 1.00000000000622 6.22155684819432e-12 87 0 0 26 5310 WP2064 Neural Crest Differentiation 1.00000000000631 6.30995220854245e-12 102 0 0 26 5310 WP188 Focal Adhesion 1.00000000000654 6.54065690497418e-12 1 0 0 26 5310 WP2536 Colchicine Metabolic Pathway 1.00000000000654 6.54065690497418e-12 1 0 0 26 5310 WP108 Selenium metabolism/Selenoproteins 1.00000000000654 6.54065690497418e-12 1 0 0 26 5310 WP1 Statin Pathway 1.00000000000654 6.54065690497418e-12 1 0 0 26 5310 WP3191 TSLP Signaling Pathway 1.00000000000654 6.54065690497418e-12 1 0 0 26 5310 WP3627 Gut-Liver Indole Metabolism 1.00000000000654 6.54065690497418e-12 1 0 0 26 5310 WP2190 One carbon donor 1.00000000000654 6.54065690497418e-12 1 0 0 26 5310 WP661 Glucose Homeostasis 1.00000000000654 6.54065690497418e-12 1 0 0 26 5310 WP2911 miRNA targets in ECM and membrane receptors 1.0000000000075 7.49543803045916e-12 43 0 0 26 5310 WP366 TGF-beta Signaling Pathway 1.00000000000798 7.98226279988636e-12 133 0 0 26 5310 WP2446 Retinoblastoma (RB) in Cancer 1.00000000000932 9.31951217821863e-12 88 0 0 26 5310 WP3849 MAPK and NFkB Signalling Pathways Inhibited by Yersinia YopJ 1.00000000000974 9.73568071294728e-12 12 0 0 26 5310 WP1559 TFs Regulate miRNAs related to cardiac hypertrophy 1.00000000000974 9.73568071294728e-12 12 0 0 26 5310 WP2007 Iron metabolism in placenta 1.00000000000974 9.73568071294728e-12 12 0 0 26 5310 WP1425 Bone Morphogenic Protein (BMP) Signalling and Regulation 1.00000000000974 9.73568071294728e-12 12 0 0 26 5310 WP2290 RalA downstream regulated genes 1.00000000000974 9.73568071294728e-12 12 0 0 26 5310 WP106 Alanine and aspartate metabolism 1.00000000000974 9.73568071294728e-12 12 0 0 26 5310 WP3301 MFAP5-mediated ovarian cancer cell motility and invasiveness 1.00000000000974 9.73568071294728e-12 12 0 0 26 5310 WP702 Metapathway biotransformation 1.00000000001083 1.08289448697969e-11 177 0 0 26 5310 WP3594 Circadian rythm related genes 1.00000000001088 1.08810189156957e-11 207 0 0 26 5310