TermID Term Enrichment logP Genes in Term Target Genes in Term Fraction of Targets in Term Total Target Genes Total Genes Entrez Gene IDs Gene Symbols hsa04970 Salivary secretion 2.19360440895221e-05 -10.7273794252301 90 5 0.178571428571429 28 7161 477,5578,108,6263,23236 ATP1A2,PRKCA,ADCY2,RYR3,PLCB1 ko04970 Salivary secretion 2.19360440895221e-05 -10.7273794252301 90 5 0.178571428571429 28 7161 23236,6263,5578,108,477 PLCB1,RYR3,PRKCA,ADCY2,ATP1A2 ko04071 Sphingolipid signaling pathway 8.09863526866325e-05 -9.4212299028373 118 5 0.178571428571429 28 7161 23236,5602,4217,5578,2534 PLCB1,MAPK10,MAP3K5,PRKCA,FYN hsa04071 Sphingolipid signaling pathway 8.09863526866325e-05 -9.4212299028373 118 5 0.178571428571429 28 7161 23236,5602,4217,5578,2534 PLCB1,MAPK10,MAP3K5,PRKCA,FYN ko04918 Thyroid hormone synthesis 0.000178306953530122 -8.63200403480839 74 4 0.142857142857143 28 7161 108,5578,477,23236 ADCY2,PRKCA,ATP1A2,PLCB1 hsa04918 Thyroid hormone synthesis 0.000178306953530122 -8.63200403480839 74 4 0.142857142857143 28 7161 23236,5578,108,477 PLCB1,PRKCA,ADCY2,ATP1A2 hsa04971 Gastric acid secretion 0.000187847103098665 -8.57988220741713 75 4 0.142857142857143 28 7161 477,108,5578,23236 ATP1A2,ADCY2,PRKCA,PLCB1 ko04971 Gastric acid secretion 0.000187847103098665 -8.57988220741713 75 4 0.142857142857143 28 7161 23236,477,5578,108 PLCB1,ATP1A2,PRKCA,ADCY2 hsa04911 Insulin secretion 0.000304634877583074 -8.09639662115904 85 4 0.142857142857143 28 7161 23236,5578,108,477 PLCB1,PRKCA,ADCY2,ATP1A2 ko04912 GnRH signaling pathway 0.000412557811914172 -7.79313421191468 92 4 0.142857142857143 28 7161 5602,23236,5578,108 MAPK10,PLCB1,PRKCA,ADCY2 hsa04912 GnRH signaling pathway 0.000412557811914172 -7.79313421191468 92 4 0.142857142857143 28 7161 5578,108,5602,23236 PRKCA,ADCY2,MAPK10,PLCB1 ko04972 Pancreatic secretion 0.000466278640725267 -7.67072716106387 95 4 0.142857142857143 28 7161 23236,477,5578,108 PLCB1,ATP1A2,PRKCA,ADCY2 hsa04972 Pancreatic secretion 0.000466278640725267 -7.67072716106387 95 4 0.142857142857143 28 7161 23236,477,108,5578 PLCB1,ATP1A2,ADCY2,PRKCA ko04713 Circadian entrainment 0.00048524642314603 -7.6308537070994 96 4 0.142857142857143 28 7161 23236,6263,108,5578 PLCB1,RYR3,ADCY2,PRKCA hsa04713 Circadian entrainment 0.00048524642314603 -7.6308537070994 96 4 0.142857142857143 28 7161 5578,108,6263,23236 PRKCA,ADCY2,RYR3,PLCB1 hsa04360 Axon guidance 0.000499196738893894 -7.60251027359487 174 5 0.178571428571429 28 7161 658,56288,2534,5578,3983 BMPR1B,PARD3,FYN,PRKCA,ABLIM1 ko04360 Axon guidance 0.000499196738893894 -7.60251027359487 174 5 0.178571428571429 28 7161 56288,658,3983,5578,2534 PARD3,BMPR1B,ABLIM1,PRKCA,FYN ko04750 Inflammatory mediator regulation of TRP channels 0.000504759556917203 -7.5914283669888 97 4 0.142857142857143 28 7161 5578,108,5602,23236 PRKCA,ADCY2,MAPK10,PLCB1 hsa04750 Inflammatory mediator regulation of TRP channels 0.000504759556917203 -7.5914283669888 97 4 0.142857142857143 28 7161 108,5578,23236,5602 ADCY2,PRKCA,PLCB1,MAPK10 hsa04723 Retrograde endocannabinoid signaling 0.000588445877806473 -7.43802560183725 101 4 0.142857142857143 28 7161 23236,5602,108,5578 PLCB1,MAPK10,ADCY2,PRKCA ko04723 Retrograde endocannabinoid signaling 0.000588445877806473 -7.43802560183725 101 4 0.142857142857143 28 7161 23236,5602,5578,108 PLCB1,MAPK10,PRKCA,ADCY2 ko04961 Endocrine and other factor-regulated calcium reabsorption 0.000773790756092788 -7.16420906188864 47 3 0.107142857142857 28 7161 5578,477,23236 PRKCA,ATP1A2,PLCB1 hsa04961 Endocrine and other factor-regulated calcium reabsorption 0.000773790756092788 -7.16420906188864 47 3 0.107142857142857 28 7161 23236,477,5578 PLCB1,ATP1A2,PRKCA hsa04725 Cholinergic synapse 0.000869065525608797 -7.04809203207921 112 4 0.142857142857143 28 7161 108,2534,5578,23236 ADCY2,FYN,PRKCA,PLCB1 hsa04724 Glutamatergic synapse 0.000928717726866191 -6.98170571153613 114 4 0.142857142857143 28 7161 5578,108,6506,23236 PRKCA,ADCY2,SLC1A2,PLCB1 ko04724 Glutamatergic synapse 0.000928717726866191 -6.98170571153613 114 4 0.142857142857143 28 7161 23236,6506,108,5578 PLCB1,SLC1A2,ADCY2,PRKCA ko04664 Fc epsilon RI signaling pathway 0.00216964389957701 -6.13319222647332 67 3 0.107142857142857 28 7161 5602,5578,2534 MAPK10,PRKCA,FYN hsa04664 Fc epsilon RI signaling pathway 0.00216964389957701 -6.13319222647332 67 3 0.107142857142857 28 7161 2534,5578,5602 FYN,PRKCA,MAPK10 hsa04261 Adrenergic signaling in cardiomyocytes 0.00220585469459782 -6.11664022858958 144 4 0.142857142857143 28 7161 23236,477,108,5578 PLCB1,ATP1A2,ADCY2,PRKCA ko04261 Adrenergic signaling in cardiomyocytes 0.00220585469459782 -6.11664022858958 144 4 0.142857142857143 28 7161 23236,5578,108,477 PLCB1,PRKCA,ADCY2,ATP1A2 ko04072 Phospholipase D signaling pathway 0.00226234946002829 -6.09135142160795 145 4 0.142857142857143 28 7161 2534,5578,108,23236 FYN,PRKCA,ADCY2,PLCB1 hsa04072 Phospholipase D signaling pathway 0.00226234946002829 -6.09135142160795 145 4 0.142857142857143 28 7161 23236,108,2534,5578 PLCB1,ADCY2,FYN,PRKCA hsa04976 Bile secretion 0.00256168711653836 -5.96708920765771 71 3 0.107142857142857 28 7161 477,361,108 ATP1A2,AQP4,ADCY2 ko04976 Bile secretion 0.00256168711653836 -5.96708920765771 71 3 0.107142857142857 28 7161 477,361,108 ATP1A2,AQP4,ADCY2 hsa04520 Adherens junction 0.00266609588258429 -5.927140092912 72 3 0.107142857142857 28 7161 56288,10580,2534 PARD3,SORBS1,FYN ko04520 Adherens junction 0.00266609588258429 -5.927140092912 72 3 0.107142857142857 28 7161 56288,2534,10580 PARD3,FYN,SORBS1 ko04921 Oxytocin signaling pathway 0.00268621368362139 -5.91962262945813 152 4 0.142857142857143 28 7161 23236,6263,108,5578 PLCB1,RYR3,ADCY2,PRKCA hsa04921 Oxytocin signaling pathway 0.00268621368362139 -5.91962262945813 152 4 0.142857142857143 28 7161 5578,108,6263,23236 PRKCA,ADCY2,RYR3,PLCB1 hsa_M00688 MAPK (JNK) signaling 0.00295724667834954 -5.8234966197618 21 2 0.0714285714285714 28 7161 4217,5602 MAP3K5,MAPK10 M00688 MAPK (JNK) signaling 0.00295724667834954 -5.8234966197618 21 2 0.0714285714285714 28 7161 5602,4217 MAPK10,MAP3K5 ko04925 Aldosterone synthesis and secretion 0.00385694331627138 -5.55788029618984 82 3 0.107142857142857 28 7161 23236,108,5578 PLCB1,ADCY2,PRKCA hsa04925 Aldosterone synthesis and secretion 0.00385694331627138 -5.55788029618984 82 3 0.107142857142857 28 7161 108,5578,23236 ADCY2,PRKCA,PLCB1 ko04012 ErbB signaling pathway 0.00426808116749061 -5.45659092803588 85 3 0.107142857142857 28 7161 5602,10718,5578 MAPK10,NRG3,PRKCA hsa04012 ErbB signaling pathway 0.00426808116749061 -5.45659092803588 85 3 0.107142857142857 28 7161 5578,10718,5602 PRKCA,NRG3,MAPK10 hsa04540 Gap junction 0.00470499872302736 -5.35912977735241 88 3 0.107142857142857 28 7161 23236,108,5578 PLCB1,ADCY2,PRKCA ko04540 Gap junction 0.00470499872302736 -5.35912977735241 88 3 0.107142857142857 28 7161 5578,108,23236 PRKCA,ADCY2,PLCB1 ko04020 Calcium signaling pathway 0.00502874166503826 -5.29258549216359 181 4 0.142857142857143 28 7161 5578,108,6263,23236 PRKCA,ADCY2,RYR3,PLCB1 hsa04020 Calcium signaling pathway 0.00502874166503826 -5.29258549216359 181 4 0.142857142857143 28 7161 6263,23236,5578,108 RYR3,PLCB1,PRKCA,ADCY2 ko04933 AGE-RAGE signaling pathway in diabetic complications 0.00653495439127086 -5.03058991107784 99 3 0.107142857142857 28 7161 5578,5602,23236 PRKCA,MAPK10,PLCB1 hsa04933 AGE-RAGE signaling pathway in diabetic complications 0.00653495439127086 -5.03058991107784 99 3 0.107142857142857 28 7161 23236,5602,5578 PLCB1,MAPK10,PRKCA hsa04916 Melanogenesis 0.00690722735901876 -4.97518697222888 101 3 0.107142857142857 28 7161 23236,5578,108 PLCB1,PRKCA,ADCY2 ko04916 Melanogenesis 0.00690722735901876 -4.97518697222888 101 3 0.107142857142857 28 7161 23236,108,5578 PLCB1,ADCY2,PRKCA ko05143 African trypanosomiasis 0.00765621528156752 -4.87223750589982 34 2 0.0714285714285714 28 7161 23236,5578 PLCB1,PRKCA hsa05143 African trypanosomiasis 0.00765621528156752 -4.87223750589982 34 2 0.0714285714285714 28 7161 5578,23236 PRKCA,PLCB1 ko04015 Rap1 signaling pathway 0.00846920800257879 -4.7713182808792 210 4 0.142857142857143 28 7161 108,5578,56288,23236 ADCY2,PRKCA,PARD3,PLCB1 hsa04015 Rap1 signaling pathway 0.00846920800257879 -4.7713182808792 210 4 0.142857142857143 28 7161 23236,56288,5578,108 PLCB1,PARD3,PRKCA,ADCY2 ko04960 Aldosterone-regulated sodium reabsorption 0.0090237768060359 -4.70789231790599 37 2 0.0714285714285714 28 7161 5578,477 PRKCA,ATP1A2 hsa04960 Aldosterone-regulated sodium reabsorption 0.0090237768060359 -4.70789231790599 37 2 0.0714285714285714 28 7161 477,5578 ATP1A2,PRKCA hsa04919 Thyroid hormone signaling pathway 0.0101030372613067 -4.59491918140055 116 3 0.107142857142857 28 7161 23236,5578,477 PLCB1,PRKCA,ATP1A2 hsa04722 Neurotrophin signaling pathway 0.0108297262522383 -4.52546049509033 119 3 0.107142857142857 28 7161 5602,4915,4217 MAPK10,NTRK2,MAP3K5 ko04722 Neurotrophin signaling pathway 0.0108297262522383 -4.52546049509033 119 3 0.107142857142857 28 7161 5602,4217,4915 MAPK10,MAP3K5,NTRK2 ko04270 Vascular smooth muscle contraction 0.0113307230184802 -4.48023739146106 121 3 0.107142857142857 28 7161 5578,108,23236 PRKCA,ADCY2,PLCB1 hsa04270 Vascular smooth muscle contraction 0.0113307230184802 -4.48023739146106 121 3 0.107142857142857 28 7161 23236,108,5578 PLCB1,ADCY2,PRKCA hsa04611 Platelet activation 0.011845029359206 -4.4358469627585 123 3 0.107142857142857 28 7161 108,2534,23236 ADCY2,FYN,PLCB1 ko04728 Dopaminergic synapse 0.0137508065621518 -4.28665779752435 130 3 0.107142857142857 28 7161 5578,5602,23236 PRKCA,MAPK10,PLCB1 hsa04728 Dopaminergic synapse 0.0137508065621518 -4.28665779752435 130 3 0.107142857142857 28 7161 23236,5602,5578 PLCB1,MAPK10,PRKCA hsa04371 Apelin signaling pathway 0.0161324476161713 -4.1269226552588 138 3 0.107142857142857 28 7161 108,6263,23236 ADCY2,RYR3,PLCB1 hsa04010 MAPK signaling pathway 0.0164037289768253 -4.11024659336244 255 4 0.142857142857143 28 7161 5602,4217,5578,4915 MAPK10,MAP3K5,PRKCA,NTRK2 ko04010 MAPK signaling pathway 0.0164037289768253 -4.11024659336244 255 4 0.142857142857143 28 7161 4217,5578,4915,5602 MAP3K5,PRKCA,NTRK2,MAPK10 ko05014 Amyotrophic lateral sclerosis (ALS) 0.0167036144260067 -4.09213015028259 51 2 0.0714285714285714 28 7161 4217,6506 MAP3K5,SLC1A2 hsa05014 Amyotrophic lateral sclerosis (ALS) 0.0167036144260067 -4.09213015028259 51 2 0.0714285714285714 28 7161 6506,4217 SLC1A2,MAP3K5 hsa05418 Fluid shear stress and atherosclerosis 0.0174055550039461 -4.05096587061173 142 3 0.107142857142857 28 7161 4217,658,5602 MAP3K5,BMPR1B,MAPK10 ko05418 Fluid shear stress and atherosclerosis 0.0174055550039461 -4.05096587061173 142 3 0.107142857142857 28 7161 4217,5602,658 MAP3K5,MAPK10,BMPR1B ko04310 Wnt signaling pathway 0.0177324523172353 -4.03235885389572 143 3 0.107142857142857 28 7161 5602,23236,5578 MAPK10,PLCB1,PRKCA hsa04310 Wnt signaling pathway 0.0177324523172353 -4.03235885389572 143 3 0.107142857142857 28 7161 5578,23236,5602 PRKCA,PLCB1,MAPK10 hsa05130 Pathogenic Escherichia coli infection 0.0192690077463302 -3.94925729002848 55 2 0.0714285714285714 28 7161 5578,2534 PRKCA,FYN ko05130 Pathogenic Escherichia coli infection 0.0192690077463302 -3.94925729002848 55 2 0.0714285714285714 28 7161 2534,5578 FYN,PRKCA ko04730 Long-term depression 0.0226935272285512 -3.78567553927278 60 2 0.0714285714285714 28 7161 5578,23236 PRKCA,PLCB1 hsa04730 Long-term depression 0.0226935272285512 -3.78567553927278 60 2 0.0714285714285714 28 7161 23236,5578 PLCB1,PRKCA hsa04022 cGMP-PKG signaling pathway 0.0249996456948963 -3.68889362641851 163 3 0.107142857142857 28 7161 477,108,23236 ATP1A2,ADCY2,PLCB1 ko04022 cGMP-PKG signaling pathway 0.0249996456948963 -3.68889362641851 163 3 0.107142857142857 28 7161 108,477,23236 ADCY2,ATP1A2,PLCB1 ko04530 Tight junction 0.0278726459276915 -3.58010950379256 170 3 0.107142857142857 28 7161 4217,56288,5602 MAP3K5,PARD3,MAPK10 hsa04530 Tight junction 0.0278726459276915 -3.58010950379256 170 3 0.107142857142857 28 7161 5602,56288,4217 MAPK10,PARD3,MAP3K5 ko04720 Long-term potentiation 0.0278766869484087 -3.57996453270445 67 2 0.0714285714285714 28 7161 5578,23236 PRKCA,PLCB1 hsa04720 Long-term potentiation 0.0278766869484087 -3.57996453270445 67 2 0.0714285714285714 28 7161 5578,23236 PRKCA,PLCB1 ko05120 Epithelial cell signaling in Helicobacter pylori infection 0.0286528331593862 -3.55250295207578 68 2 0.0714285714285714 28 7161 5803,5602 PTPRZ1,MAPK10 hsa05120 Epithelial cell signaling in Helicobacter pylori infection 0.0286528331593862 -3.55250295207578 68 2 0.0714285714285714 28 7161 5602,5803 MAPK10,PTPRZ1 hsa04062 Chemokine signaling pathway 0.0331950305380759 -3.40535509685133 182 3 0.107142857142857 28 7161 108,56288,23236 ADCY2,PARD3,PLCB1 ko04062 Chemokine signaling pathway 0.0331950305380759 -3.40535509685133 182 3 0.107142857142857 28 7161 108,56288,23236 ADCY2,PARD3,PLCB1 M00078 Heparan sulfate degradation 0.03466428234209 -3.36204544946779 9 1 0.0357142857142857 28 7161 60495 HPSE2 hsa_M00078 Heparan sulfate degradation 0.03466428234209 -3.36204544946779 9 1 0.0357142857142857 28 7161 60495 HPSE2 hsa_M00035 Methionine degradation 0.0384435608786861 -3.25856406444909 10 1 0.0357142857142857 28 7161 10768 AHCYL1 M00035 Methionine degradation 0.0384435608786861 -3.25856406444909 10 1 0.0357142857142857 28 7161 10768 AHCYL1 ko04510 Focal adhesion 0.0410663319030656 -3.19256666829512 198 3 0.107142857142857 28 7161 2534,5578,5602 FYN,PRKCA,MAPK10 hsa04024 cAMP signaling pathway 0.0410663319030656 -3.19256666829512 198 3 0.107142857142857 28 7161 477,108,5602 ATP1A2,ADCY2,MAPK10 hsa04510 Focal adhesion 0.0410663319030656 -3.19256666829512 198 3 0.107142857142857 28 7161 2534,5578,5602 FYN,PRKCA,MAPK10 ko04024 cAMP signaling pathway 0.0410663319030656 -3.19256666829512 198 3 0.107142857142857 28 7161 5602,108,477 MAPK10,ADCY2,ATP1A2 ko04727 GABAergic synapse 0.045905302519245 -3.08117464529284 88 2 0.0714285714285714 28 7161 108,5578 ADCY2,PRKCA hsa04727 GABAergic synapse 0.045905302519245 -3.08117464529284 88 2 0.0714285714285714 28 7161 108,5578 ADCY2,PRKCA ko05032 Morphine addiction 0.0487578353822846 -3.02088936866283 91 2 0.0714285714285714 28 7161 108,5578 ADCY2,PRKCA hsa05032 Morphine addiction 0.0487578353822846 -3.02088936866283 91 2 0.0714285714285714 28 7161 5578,108 PRKCA,ADCY2 ko04914 Progesterone-mediated oocyte maturation 0.0497229324043928 -3.00128903571207 92 2 0.0714285714285714 28 7161 5602,108 MAPK10,ADCY2 hsa04914 Progesterone-mediated oocyte maturation 0.0497229324043928 -3.00128903571207 92 2 0.0714285714285714 28 7161 108,5602 ADCY2,MAPK10 ko05146 Amoebiasis 0.051674111658892 -2.96279836448821 94 2 0.0714285714285714 28 7161 23236,5578 PLCB1,PRKCA hsa05146 Amoebiasis 0.051674111658892 -2.96279836448821 94 2 0.0714285714285714 28 7161 5578,23236 PRKCA,PLCB1 ko01522 Endocrine resistance 0.0526600638951784 -2.94389791156153 95 2 0.0714285714285714 28 7161 5602,108 MAPK10,ADCY2 hsa01522 Endocrine resistance 0.0526600638951784 -2.94389791156153 95 2 0.0714285714285714 28 7161 5602,108 MAPK10,ADCY2 hsa04070 Phosphatidylinositol signaling system 0.0546523713594781 -2.90676267354475 97 2 0.0714285714285714 28 7161 23236,5578 PLCB1,PRKCA ko04070 Phosphatidylinositol signaling system 0.0546523713594781 -2.90676267354475 97 2 0.0714285714285714 28 7161 5578,23236 PRKCA,PLCB1 ko04915 Estrogen signaling pathway 0.0556585987942816 -2.88851869757638 98 2 0.0714285714285714 28 7161 23236,108 PLCB1,ADCY2 hsa04915 Estrogen signaling pathway 0.0556585987942816 -2.88851869757638 98 2 0.0714285714285714 28 7161 23236,108 PLCB1,ADCY2 ko05231 Choline metabolism in cancer 0.056671457441154 -2.87048459109436 99 2 0.0714285714285714 28 7161 5602,5578 MAPK10,PRKCA hsa05231 Choline metabolism in cancer 0.056671457441154 -2.87048459109436 99 2 0.0714285714285714 28 7161 5578,5602 PRKCA,MAPK10 hsa05142 Chagas disease (American trypanosomiasis) 0.0597491925600438 -2.81759960190126 102 2 0.0714285714285714 28 7161 23236,5602 PLCB1,MAPK10 hsa04922 Glucagon signaling pathway 0.0597491925600438 -2.81759960190126 102 2 0.0714285714285714 28 7161 108,23236 ADCY2,PLCB1 ko05142 Chagas disease (American trypanosomiasis) 0.0597491925600438 -2.81759960190126 102 2 0.0714285714285714 28 7161 5602,23236 MAPK10,PLCB1 ko04922 Glucagon signaling pathway 0.0597491925600438 -2.81759960190126 102 2 0.0714285714285714 28 7161 108,23236 ADCY2,PLCB1 M00695 cAMP signaling 0.0608213843454808 -2.7998138356391 16 1 0.0357142857142857 28 7161 108 ADCY2 hsa_M00695 cAMP signaling 0.0608213843454808 -2.7998138356391 16 1 0.0357142857142857 28 7161 108 ADCY2 hsa04659 Th17 cell differentiation 0.0650055666118792 -2.73328237257065 107 2 0.0714285714285714 28 7161 5602,6095 MAPK10,RORA ko04659 Th17 cell differentiation 0.0650055666118792 -2.73328237257065 107 2 0.0714285714285714 28 7161 5602,6095 MAPK10,RORA hsa05200 Pathways in cancer 0.0655033238645326 -2.72565439160507 395 4 0.142857142857143 28 7161 5578,108,5602,23236 PRKCA,ADCY2,MAPK10,PLCB1 hsa04668 TNF signaling pathway 0.0660753144393593 -2.71696005967815 108 2 0.0714285714285714 28 7161 4217,5602 MAP3K5,MAPK10 ko04668 TNF signaling pathway 0.0660753144393593 -2.71696005967815 108 2 0.0714285714285714 28 7161 4217,5602 MAP3K5,MAPK10 hsa04726 Serotonergic synapse 0.0704138857407899 -2.6533647946313 112 2 0.0714285714285714 28 7161 5578,23236 PRKCA,PLCB1 hsa00531 Glycosaminoglycan degradation 0.0718211331468341 -2.63357651271421 19 1 0.0357142857142857 28 7161 60495 HPSE2 ko00531 Glycosaminoglycan degradation 0.0718211331468341 -2.63357651271421 19 1 0.0357142857142857 28 7161 60495 HPSE2 hsa_M00679 BMP signaling 0.0754600309733677 -2.58415215398531 20 1 0.0357142857142857 28 7161 658 BMPR1B M00679 BMP signaling 0.0754600309733677 -2.58415215398531 20 1 0.0357142857142857 28 7161 658 BMPR1B M00689 MAPK (p38) signaling 0.0826966008932813 -2.49257677945038 22 1 0.0357142857142857 28 7161 4217 MAP3K5 hsa_M00689 MAPK (p38) signaling 0.0826966008932813 -2.49257677945038 22 1 0.0357142857142857 28 7161 4217 MAP3K5 hsa_M00130 Inositol phosphate metabolism, PI=> PIP2 => Ins(1,4,5)P3 => Ins(1,3,4,5)P4 0.0826966008932813 -2.49257677945038 22 1 0.0357142857142857 28 7161 23236 PLCB1 M00130 Inositol phosphate metabolism, PI=> PIP2 => Ins(1,4,5)P3 => Ins(1,3,4,5)P4 0.0826966008932813 -2.49257677945038 22 1 0.0357142857142857 28 7161 23236 PLCB1 hsa04964 Proximal tubule bicarbonate reclamation 0.0862943730143232 -2.44999088563356 23 1 0.0357142857142857 28 7161 477 ATP1A2 ko04964 Proximal tubule bicarbonate reclamation 0.0862943730143232 -2.44999088563356 23 1 0.0357142857142857 28 7161 477 ATP1A2 ko04380 Osteoclast differentiation 0.0898408997715766 -2.40971495333522 129 2 0.0714285714285714 28 7161 5602,2534 MAPK10,FYN hsa04380 Osteoclast differentiation 0.0898408997715766 -2.40971495333522 129 2 0.0714285714285714 28 7161 5602,2534 MAPK10,FYN hsa04650 Natural killer cell mediated cytotoxicity 0.0934219279602688 -2.3706291865674 132 2 0.0714285714285714 28 7161 2534,5578 FYN,PRKCA ko04650 Natural killer cell mediated cytotoxicity 0.0934219279602688 -2.3706291865674 132 2 0.0714285714285714 28 7161 5578,2534 PRKCA,FYN hsa04910 Insulin signaling pathway 0.100709004164023 -2.29552006752485 138 2 0.0714285714285714 28 7161 10580,5602 SORBS1,MAPK10 ko04210 Apoptosis 0.100709004164023 -2.29552006752485 138 2 0.0714285714285714 28 7161 5602,4217 MAPK10,MAP3K5 hsa04210 Apoptosis 0.100709004164023 -2.29552006752485 138 2 0.0714285714285714 28 7161 4217,5602 MAP3K5,MAPK10 ko04910 Insulin signaling pathway 0.100709004164023 -2.29552006752485 138 2 0.0714285714285714 28 7161 5602,10580 MAPK10,SORBS1 ko04320 Dorso-ventral axis formation 0.104080090067814 -2.26259457940726 28 1 0.0357142857142857 28 7161 56776 FMN2 hsa04320 Dorso-ventral axis formation 0.104080090067814 -2.26259457940726 28 1 0.0357142857142857 28 7161 56776 FMN2 hsa04514 Cell adhesion molecules (CAMs) 0.106902388580742 -2.23583911713396 143 2 0.0714285714285714 28 7161 4897,1272 NRCAM,CNTN1 ko04514 Cell adhesion molecules (CAMs) 0.106902388580742 -2.23583911713396 143 2 0.0714285714285714 28 7161 4897,1272 NRCAM,CNTN1 hsa05161 Hepatitis B 0.108153650312759 -2.22420237483867 144 2 0.0714285714285714 28 7161 5578,5602 PRKCA,MAPK10 ko04932 Non-alcoholic fatty liver disease (NAFLD) 0.109408993424467 -2.21266218556805 145 2 0.0714285714285714 28 7161 4217,5602 MAP3K5,MAPK10 hsa04932 Non-alcoholic fatty liver disease (NAFLD) 0.109408993424467 -2.21266218556805 145 2 0.0714285714285714 28 7161 4217,5602 MAP3K5,MAPK10 hsa04710 Circadian rhythm 0.114590774650331 -2.16638797837525 31 1 0.0357142857142857 28 7161 6095 RORA ko04710 Circadian rhythm 0.114590774650331 -2.16638797837525 31 1 0.0357142857142857 28 7161 6095 RORA ko04390 Hippo signaling pathway 0.120882902922782 -2.11293294639219 154 2 0.0714285714285714 28 7161 56288,658 PARD3,BMPR1B hsa04390 Hippo signaling pathway 0.120882902922782 -2.11293294639219 154 2 0.0714285714285714 28 7161 658,56288 BMPR1B,PARD3 hsa04215 Apoptosis - multiple species 0.121531731559858 -2.10757988519749 33 1 0.0357142857142857 28 7161 5602 MAPK10 ko04215 Apoptosis - multiple species 0.121531731559858 -2.10757988519749 33 1 0.0357142857142857 28 7161 5602 MAPK10 ko05020 Prion diseases 0.128420205055222 -2.05244753986294 35 1 0.0357142857142857 28 7161 2534 FYN hsa05020 Prion diseases 0.128420205055222 -2.05244753986294 35 1 0.0357142857142857 28 7161 2534 FYN hsa04141 Protein processing in endoplasmic reticulum 0.135300960446096 -2.00025364518982 165 2 0.0714285714285714 28 7161 4217,5602 MAP3K5,MAPK10 hsa05010 Alzheimer's disease 0.135300960446096 -2.00025364518982 165 2 0.0714285714285714 28 7161 23236,6263 PLCB1,RYR3 ko05010 Alzheimer's disease 0.135300960446096 -2.00025364518982 165 2 0.0714285714285714 28 7161 6263,23236 RYR3,PLCB1 ko04141 Protein processing in endoplasmic reticulum 0.135300960446096 -2.00025364518982 165 2 0.0714285714285714 28 7161 5602,4217 MAPK10,MAP3K5 ko04621 NOD-like receptor signaling pathway 0.140640831208018 -1.96154593488058 169 2 0.0714285714285714 28 7161 5602,23236 MAPK10,PLCB1 hsa04621 NOD-like receptor signaling pathway 0.140640831208018 -1.96154593488058 169 2 0.0714285714285714 28 7161 5602,23236 MAPK10,PLCB1 hsa05164 Influenza A 0.144676989424548 -1.93325168062629 172 2 0.0714285714285714 28 7161 5578,5602 PRKCA,MAPK10 ko05164 Influenza A 0.144676989424548 -1.93325168062629 172 2 0.0714285714285714 28 7161 5602,5578 MAPK10,PRKCA ko04216 Ferroptosis 0.145414275852639 -1.92816853539675 40 1 0.0357142857142857 28 7161 23657 SLC7A11 hsa04216 Ferroptosis 0.145414275852639 -1.92816853539675 40 1 0.0357142857142857 28 7161 23657 SLC7A11 ko04975 Fat digestion and absorption 0.148774534282241 -1.9053233118057 41 1 0.0357142857142857 28 7161 19 ABCA1 hsa04975 Fat digestion and absorption 0.148774534282241 -1.9053233118057 41 1 0.0357142857142857 28 7161 19 ABCA1 hsa04962 Vasopressin-regulated water reabsorption 0.158779040241004 -1.84024172728711 44 1 0.0357142857142857 28 7161 361 AQP4 ko04973 Carbohydrate digestion and absorption 0.158779040241004 -1.84024172728711 44 1 0.0357142857142857 28 7161 477 ATP1A2 hsa00270 Cysteine and methionine metabolism 0.158779040241004 -1.84024172728711 44 1 0.0357142857142857 28 7161 10768 AHCYL1 hsa02010 ABC transporters 0.158779040241004 -1.84024172728711 44 1 0.0357142857142857 28 7161 19 ABCA1 ko02010 ABC transporters 0.158779040241004 -1.84024172728711 44 1 0.0357142857142857 28 7161 19 ABCA1 hsa04973 Carbohydrate digestion and absorption 0.158779040241004 -1.84024172728711 44 1 0.0357142857142857 28 7161 477 ATP1A2 ko00270 Cysteine and methionine metabolism 0.158779040241004 -1.84024172728711 44 1 0.0357142857142857 28 7161 10768 AHCYL1 ko04962 Vasopressin-regulated water reabsorption 0.158779040241004 -1.84024172728711 44 1 0.0357142857142857 28 7161 361 AQP4 hsa04930 Type II diabetes mellitus 0.165385616450966 -1.79947546238095 46 1 0.0357142857142857 28 7161 5602 MAPK10 ko04930 Type II diabetes mellitus 0.165385616450966 -1.79947546238095 46 1 0.0357142857142857 28 7161 5602 MAPK10 ko04913 Ovarian steroidogenesis 0.17844899567093 -1.72345245713169 50 1 0.0357142857142857 28 7161 108 ADCY2 hsa04913 Ovarian steroidogenesis 0.17844899567093 -1.72345245713169 50 1 0.0357142857142857 28 7161 108 ADCY2 ko04978 Mineral absorption 0.181683903297416 -1.70548689695164 51 1 0.0357142857142857 28 7161 477 ATP1A2 hsa05110 Vibrio cholerae infection 0.181683903297416 -1.70548689695164 51 1 0.0357142857142857 28 7161 5578 PRKCA hsa04978 Mineral absorption 0.181683903297416 -1.70548689695164 51 1 0.0357142857142857 28 7161 477 ATP1A2 ko05110 Vibrio cholerae infection 0.181683903297416 -1.70548689695164 51 1 0.0357142857142857 28 7161 5578 PRKCA hsa05205 Proteoglycans in cancer 0.187689989261799 -1.67296367052641 203 2 0.0714285714285714 28 7161 5578,60495 PRKCA,HPSE2 ko05205 Proteoglycans in cancer 0.187689989261799 -1.67296367052641 203 2 0.0714285714285714 28 7161 5578,60495 PRKCA,HPSE2 hsa04923 Regulation of lipolysis in adipocytes 0.191315098971161 -1.65383347741662 54 1 0.0357142857142857 28 7161 108 ADCY2 ko05223 Non-small cell lung cancer 0.203986796771434 -1.58970000894112 58 1 0.0357142857142857 28 7161 5578 PRKCA hsa05416 Viral myocarditis 0.203986796771434 -1.58970000894112 58 1 0.0357142857142857 28 7161 2534 FYN hsa05223 Non-small cell lung cancer 0.203986796771434 -1.58970000894112 58 1 0.0357142857142857 28 7161 5578 PRKCA ko04370 VEGF signaling pathway 0.207124677904763 -1.5744343583132 59 1 0.0357142857142857 28 7161 5578 PRKCA hsa04370 VEGF signaling pathway 0.207124677904763 -1.5744343583132 59 1 0.0357142857142857 28 7161 5578 PRKCA ko05210 Colorectal cancer 0.210250629609165 -1.55945498555965 60 1 0.0357142857142857 28 7161 5602 MAPK10 hsa05210 Colorectal cancer 0.210250629609165 -1.55945498555965 60 1 0.0357142857142857 28 7161 5602 MAPK10 hsa04213 Longevity regulating pathway - multiple species 0.21646691930372 -1.53031754088769 62 1 0.0357142857142857 28 7161 108 ADCY2 ko04213 Longevity regulating pathway - multiple species 0.21646691930372 -1.53031754088769 62 1 0.0357142857142857 28 7161 108 ADCY2 hsa04014 Ras signaling pathway 0.220719925514288 -1.51086068654015 226 2 0.0714285714285714 28 7161 5602,5578 MAPK10,PRKCA hsa05131 Shigellosis 0.222636013443377 -1.50221706776664 64 1 0.0357142857142857 28 7161 5602 MAPK10 hsa05214 Glioma 0.222636013443377 -1.50221706776664 64 1 0.0357142857142857 28 7161 5578 PRKCA hsa05212 Pancreatic cancer 0.222636013443377 -1.50221706776664 64 1 0.0357142857142857 28 7161 5602 MAPK10 ko04137 Mitophagy - animal 0.222636013443377 -1.50221706776664 64 1 0.0357142857142857 28 7161 5602 MAPK10 ko05212 Pancreatic cancer 0.222636013443377 -1.50221706776664 64 1 0.0357142857142857 28 7161 5602 MAPK10 hsa04137 Mitophagy - animal 0.222636013443377 -1.50221706776664 64 1 0.0357142857142857 28 7161 5602 MAPK10 ko05214 Glioma 0.222636013443377 -1.50221706776664 64 1 0.0357142857142857 28 7161 5578 PRKCA hsa04924 Renin secretion 0.225702970130644 -1.4885354356057 65 1 0.0357142857142857 28 7161 23236 PLCB1 hsa05321 Inflammatory bowel disease (IBD) 0.225702970130644 -1.4885354356057 65 1 0.0357142857142857 28 7161 6095 RORA ko04924 Renin secretion 0.225702970130644 -1.4885354356057 65 1 0.0357142857142857 28 7161 23236 PLCB1 ko05321 Inflammatory bowel disease (IBD) 0.225702970130644 -1.4885354356057 65 1 0.0357142857142857 28 7161 6095 RORA hsa05031 Amphetamine addiction 0.234833993210155 -1.44887642633609 68 1 0.0357142857142857 28 7161 5578 PRKCA ko05031 Amphetamine addiction 0.234833993210155 -1.44887642633609 68 1 0.0357142857142857 28 7161 5578 PRKCA ko04920 Adipocytokine signaling pathway 0.237854527286265 -1.43609602207745 69 1 0.0357142857142857 28 7161 5602 MAPK10 hsa04920 Adipocytokine signaling pathway 0.237854527286265 -1.43609602207745 69 1 0.0357142857142857 28 7161 5602 MAPK10 hsa04917 Prolactin signaling pathway 0.240863561861987 -1.42352463915823 70 1 0.0357142857142857 28 7161 5602 MAPK10 ko04917 Prolactin signaling pathway 0.240863561861987 -1.42352463915823 70 1 0.0357142857142857 28 7161 5602 MAPK10 ko04622 RIG-I-like receptor signaling pathway 0.240863561861987 -1.42352463915823 70 1 0.0357142857142857 28 7161 5602 MAPK10 hsa04622 RIG-I-like receptor signaling pathway 0.240863561861987 -1.42352463915823 70 1 0.0357142857142857 28 7161 5602 MAPK10 hsa00562 Inositol phosphate metabolism 0.24386113911283 -1.41115631768554 71 1 0.0357142857142857 28 7161 23236 PLCB1 ko00562 Inositol phosphate metabolism 0.24386113911283 -1.41115631768554 71 1 0.0357142857142857 28 7161 23236 PLCB1 ko03320 PPAR signaling pathway 0.246847301044131 -1.39898534792371 72 1 0.0357142857142857 28 7161 10580 SORBS1 hsa03320 PPAR signaling pathway 0.246847301044131 -1.39898534792371 72 1 0.0357142857142857 28 7161 10580 SORBS1 ko01524 Platinum drug resistance 0.249822089531725 -1.38700625633026 73 1 0.0357142857142857 28 7161 4217 MAP3K5 hsa01524 Platinum drug resistance 0.249822089531725 -1.38700625633026 73 1 0.0357142857142857 28 7161 4217 MAP3K5 hsa04260 Cardiac muscle contraction 0.252785546286992 -1.37521379284162 74 1 0.0357142857142857 28 7161 477 ATP1A2 ko04260 Cardiac muscle contraction 0.252785546286992 -1.37521379284162 74 1 0.0357142857142857 28 7161 477 ATP1A2 ko05133 Pertussis 0.258678630756377 -1.35216879561252 76 1 0.0357142857142857 28 7161 5602 MAPK10 hsa05133 Pertussis 0.258678630756377 -1.35216879561252 76 1 0.0357142857142857 28 7161 5602 MAPK10 hsa01521 EGFR tyrosine kinase inhibitor resistance 0.267434304066116 -1.318881335085 79 1 0.0357142857142857 28 7161 5578 PRKCA ko04610 Complement and coagulation cascades 0.267434304066116 -1.318881335085 79 1 0.0357142857142857 28 7161 1191 CLU hsa04610 Complement and coagulation cascades 0.267434304066116 -1.318881335085 79 1 0.0357142857142857 28 7161 1191 CLU ko01521 EGFR tyrosine kinase inhibitor resistance 0.267434304066116 -1.318881335085 79 1 0.0357142857142857 28 7161 5578 PRKCA ko04350 TGF-beta signaling pathway 0.281805942563453 -1.26653659186392 84 1 0.0357142857142857 28 7161 658 BMPR1B hsa04350 TGF-beta signaling pathway 0.281805942563453 -1.26653659186392 84 1 0.0357142857142857 28 7161 658 BMPR1B ko05132 Salmonella infection 0.284647462083139 -1.25650383954561 85 1 0.0357142857142857 28 7161 5602 MAPK10 hsa05132 Salmonella infection 0.284647462083139 -1.25650383954561 85 1 0.0357142857142857 28 7161 5602 MAPK10 hsa04211 Longevity regulating pathway 0.295905513601863 -1.21771508642121 89 1 0.0357142857142857 28 7161 108 ADCY2 ko04974 Protein digestion and absorption 0.295905513601863 -1.21771508642121 89 1 0.0357142857142857 28 7161 477 ATP1A2 hsa04974 Protein digestion and absorption 0.295905513601863 -1.21771508642121 89 1 0.0357142857142857 28 7161 477 ATP1A2 ko05414 Dilated cardiomyopathy 0.295905513601863 -1.21771508642121 89 1 0.0357142857142857 28 7161 108 ADCY2 hsa05414 Dilated cardiomyopathy 0.295905513601863 -1.21771508642121 89 1 0.0357142857142857 28 7161 108 ADCY2 hsa04666 Fc gamma R-mediated phagocytosis 0.298693218012352 -1.20833825903172 90 1 0.0357142857142857 28 7161 5578 PRKCA ko04666 Fc gamma R-mediated phagocytosis 0.298693218012352 -1.20833825903172 90 1 0.0357142857142857 28 7161 5578 PRKCA hsa03015 mRNA surveillance pathway 0.301470277822781 -1.19908384869329 91 1 0.0357142857142857 28 7161 124540 MSI2 ko03015 mRNA surveillance pathway 0.301470277822781 -1.19908384869329 91 1 0.0357142857142857 28 7161 124540 MSI2 hsa04658 Th1 and Th2 cell differentiation 0.304236732165243 -1.18994915639654 92 1 0.0357142857142857 28 7161 5602 MAPK10 ko04658 Th1 and Th2 cell differentiation 0.304236732165243 -1.18994915639654 92 1 0.0357142857142857 28 7161 5602 MAPK10 ko04657 IL-17 signaling pathway 0.306992620055746 -1.18093157059024 93 1 0.0357142857142857 28 7161 5602 MAPK10 hsa04657 IL-17 signaling pathway 0.306992620055746 -1.18093157059024 93 1 0.0357142857142857 28 7161 5602 MAPK10 hsa04066 HIF-1 signaling pathway 0.328663966372133 -1.11271942898765 101 1 0.0357142857142857 28 7161 5578 PRKCA hsa04660 T cell receptor signaling pathway 0.33132648888083 -1.10465101850836 102 1 0.0357142857142857 28 7161 2534 FYN ko04660 T cell receptor signaling pathway 0.33132648888083 -1.10465101850836 102 1 0.0357142857142857 28 7161 2534 FYN ko04620 Toll-like receptor signaling pathway 0.336621019741148 -1.08879755193469 104 1 0.0357142857142857 28 7161 5602 MAPK10 hsa04620 Toll-like receptor signaling pathway 0.336621019741148 -1.08879755193469 104 1 0.0357142857142857 28 7161 5602 MAPK10 hsa04931 Insulin resistance 0.344487091340299 -1.06569865994077 107 1 0.0357142857142857 28 7161 5602 MAPK10 ko05145 Toxoplasmosis 0.359950287398672 -1.0217893476266 113 1 0.0357142857142857 28 7161 5602 MAPK10 hsa05145 Toxoplasmosis 0.359950287398672 -1.0217893476266 113 1 0.0357142857142857 28 7161 5602 MAPK10 hsa04670 Leukocyte transendothelial migration 0.36249305016585 -1.01474997682747 114 1 0.0357142857142857 28 7161 5578 PRKCA ko04670 Leukocyte transendothelial migration 0.36249305016585 -1.01474997682747 114 1 0.0357142857142857 28 7161 5578 PRKCA ko04114 Oocyte meiosis 0.377546290425747 -0.974062094166359 120 1 0.0357142857142857 28 7161 108 ADCY2 hsa04114 Oocyte meiosis 0.377546290425747 -0.974062094166359 120 1 0.0357142857142857 28 7161 108 ADCY2 hsa04140 Autophagy - animal 0.394675367827338 -0.929691705589515 127 1 0.0357142857142857 28 7161 5602 MAPK10 ko04140 Autophagy - animal 0.394675367827338 -0.929691705589515 127 1 0.0357142857142857 28 7161 5602 MAPK10 ko05160 Hepatitis C 0.404258380399601 -0.905701050004855 131 1 0.0357142857142857 28 7161 5602 MAPK10 hsa05160 Hepatitis C 0.404258380399601 -0.905701050004855 131 1 0.0357142857142857 28 7161 5602 MAPK10 hsa04068 FoxO signaling pathway 0.406631177749613 -0.899848701559823 132 1 0.0357142857142857 28 7161 5602 MAPK10 hsa05162 Measles 0.408994860639045 -0.89405268869299 133 1 0.0357142857142857 28 7161 2534 FYN ko05162 Measles 0.408994860639045 -0.89405268869299 133 1 0.0357142857142857 28 7161 2534 FYN hsa04550 Signaling pathways regulating pluripotency of stem cells 0.422987434219579 -0.860412806713794 139 1 0.0357142857142857 28 7161 658 BMPR1B ko04550 Signaling pathways regulating pluripotency of stem cells 0.422987434219579 -0.860412806713794 139 1 0.0357142857142857 28 7161 658 BMPR1B ko04150 mTOR signaling pathway 0.447815170898351 -0.803374696654528 150 1 0.0357142857142857 28 7161 5578 PRKCA hsa04150 mTOR signaling pathway 0.447815170898351 -0.803374696654528 150 1 0.0357142857142857 28 7161 5578 PRKCA ko00230 Purine metabolism 0.496442326746263 -0.700287961868809 173 1 0.0357142857142857 28 7161 108 ADCY2 hsa00230 Purine metabolism 0.496442326746263 -0.700287961868809 173 1 0.0357142857142857 28 7161 108 ADCY2 hsa05152 Tuberculosis 0.506453094378907 -0.680323566928403 178 1 0.0357142857142857 28 7161 5602 MAPK10 ko05152 Tuberculosis 0.506453094378907 -0.680323566928403 178 1 0.0357142857142857 28 7161 5602 MAPK10 hsa05034 Alcoholism 0.510403428943297 -0.67255382882503 180 1 0.0357142857142857 28 7161 4915 NTRK2 ko05034 Alcoholism 0.510403428943297 -0.67255382882503 180 1 0.0357142857142857 28 7161 4915 NTRK2 ko05168 Herpes simplex infection 0.520146332910439 -0.653645097551722 185 1 0.0357142857142857 28 7161 5602 MAPK10 hsa05168 Herpes simplex infection 0.520146332910439 -0.653645097551722 185 1 0.0357142857142857 28 7161 5602 MAPK10 hsa05016 Huntington's disease 0.52399091367335 -0.646280935129474 187 1 0.0357142857142857 28 7161 23236 PLCB1 ko05016 Huntington's disease 0.52399091367335 -0.646280935129474 187 1 0.0357142857142857 28 7161 23236 PLCB1 ko05169 Epstein-Barr virus infection 0.546442150122026 -0.60432683218905 199 1 0.0357142857142857 28 7161 5602 MAPK10 hsa05169 Epstein-Barr virus infection 0.546442150122026 -0.60432683218905 199 1 0.0357142857142857 28 7161 5602 MAPK10 ko04810 Regulation of actin cytoskeleton 0.567870550205845 -0.565861790802353 211 1 0.0357142857142857 28 7161 50649 ARHGEF4 hsa04810 Regulation of actin cytoskeleton 0.567870550205845 -0.565861790802353 211 1 0.0357142857142857 28 7161 50649 ARHGEF4 ko05166 HTLV-I infection 0.639862692633688 -0.446501668405872 256 1 0.0357142857142857 28 7161 108 ADCY2 hsa05166 HTLV-I infection 0.639862692633688 -0.446501668405872 256 1 0.0357142857142857 28 7161 108 ADCY2 ko04144 Endocytosis 0.645669985617198 -0.437466763909744 260 1 0.0357142857142857 28 7161 56288 PARD3 hsa04144 Endocytosis 0.645669985617198 -0.437466763909744 260 1 0.0357142857142857 28 7161 56288 PARD3 ko04060 Cytokine-cytokine receptor interaction 0.659795887527528 -0.415824753114737 270 1 0.0357142857142857 28 7161 658 BMPR1B hsa04060 Cytokine-cytokine receptor interaction 0.659795887527528 -0.415824753114737 270 1 0.0357142857142857 28 7161 658 BMPR1B ko04080 Neuroactive ligand-receptor interaction 0.66800908900228 -0.403453499247218 276 1 0.0357142857142857 28 7161 56288 PARD3 hsa04080 Neuroactive ligand-receptor interaction 0.66800908900228 -0.403453499247218 276 1 0.0357142857142857 28 7161 56288 PARD3 hsa05206 MicroRNAs in cancer 0.697757455380408 -0.359883721735066 299 1 0.0357142857142857 28 7161 5578 PRKCA ko05206 MicroRNAs in cancer 0.697757455380408 -0.359883721735066 299 1 0.0357142857142857 28 7161 5578 PRKCA ko04151 PI3K-Akt signaling pathway 0.745580510148184 -0.293592155775121 341 1 0.0357142857142857 28 7161 5578 PRKCA hsa04151 PI3K-Akt signaling pathway 0.745580510148184 -0.293592155775121 341 1 0.0357142857142857 28 7161 5578 PRKCA hsa01100 Metabolic pathways 0.891789054981725 -0.114525659815717 1256 3 0.107142857142857 28 7161 23236,60495,10768 PLCB1,HPSE2,AHCYL1 M00354 Spliceosome, U4/U6.U5 tri-snRNP 0.999999999975404 -2.45955060662102e-11 30 0 0 28 7161 ko00030 Pentose phosphate pathway 0.999999999975404 -2.45955060662102e-11 30 0 0 28 7161 ko05310 Asthma 0.999999999975404 -2.45955060662102e-11 30 0 0 28 7161 hsa05310 Asthma 0.999999999975404 -2.45955060662102e-11 30 0 0 28 7161 hsa00020 Citrate cycle (TCA cycle) 0.999999999975404 -2.45955060662102e-11 30 0 0 28 7161 hsa00030 Pentose phosphate pathway 0.999999999975404 -2.45955060662102e-11 30 0 0 28 7161 ko00020 Citrate cycle (TCA cycle) 0.999999999975404 -2.45955060662102e-11 30 0 0 28 7161 hsa_M00354 Spliceosome, U4/U6.U5 tri-snRNP 0.999999999975404 -2.45955060662102e-11 30 0 0 28 7161 hsa_M00682 Notch signaling 0.999999999976558 -2.34415486605611e-11 16 0 0 28 7161 hsa_M00683 Hippo signaling 0.999999999976558 -2.34415486605611e-11 16 0 0 28 7161 M00075 N-glycan biosynthesis, complex type 0.999999999976558 -2.34415486605611e-11 16 0 0 28 7161 hsa_M00295 BRCA1-associated genome surveillance complex (BASC) 0.999999999976558 -2.34415486605611e-11 16 0 0 28 7161 M00683 Hippo signaling 0.999999999976558 -2.34415486605611e-11 16 0 0 28 7161 hsa_M00075 N-glycan biosynthesis, complex type 0.999999999976558 -2.34415486605611e-11 16 0 0 28 7161 hsa_M00099 Sphingosine biosynthesis 0.999999999976558 -2.34415486605611e-11 16 0 0 28 7161 M00099 Sphingosine biosynthesis 0.999999999976558 -2.34415486605611e-11 16 0 0 28 7161 M00295 BRCA1-associated genome surveillance complex (BASC) 0.999999999976558 -2.34415486605611e-11 16 0 0 28 7161 M00682 Notch signaling 0.999999999976558 -2.34415486605611e-11 16 0 0 28 7161 hsa04110 Cell cycle 0.99999999997676 -2.3239914184158e-11 124 0 0 28 7161 ko04110 Cell cycle 0.99999999997676 -2.3239914184158e-11 124 0 0 28 7161 ko05150 Staphylococcus aureus infection 0.999999999978425 -2.15747511372293e-11 55 0 0 28 7161 ko05217 Basal cell carcinoma 0.999999999978425 -2.15747511372293e-11 55 0 0 28 7161 hsa05134 Legionellosis 0.999999999978425 -2.15747511372293e-11 55 0 0 28 7161 ko05134 Legionellosis 0.999999999978425 -2.15747511372293e-11 55 0 0 28 7161 hsa05221 Acute myeloid leukemia 0.999999999978425 -2.15747511372293e-11 55 0 0 28 7161 ko05221 Acute myeloid leukemia 0.999999999978425 -2.15747511372293e-11 55 0 0 28 7161 hsa05150 Staphylococcus aureus infection 0.999999999978425 -2.15747511372293e-11 55 0 0 28 7161 hsa05217 Basal cell carcinoma 0.999999999978425 -2.15747511372293e-11 55 0 0 28 7161 hsa_M00071 Glycosphingolipid biosynthesis, neolacto-series, LacCer => nLc4Cer 0.999999999980346 -1.96536085461922e-11 5 0 0 28 7161 hsa00524 Neomycin, kanamycin and gentamicin biosynthesis 0.999999999980346 -1.96536085461922e-11 5 0 0 28 7161 hsa_M00057 Glycosaminoglycan biosynthesis, linkage tetrasaccharide 0.999999999980346 -1.96536085461922e-11 5 0 0 28 7161 M00128 Ubiquinone biosynthesis, eukaryotes, 4-hydroxybenzoate => ubiquinone 0.999999999980346 -1.96536085461922e-11 5 0 0 28 7161 hsa_M00307 Pyruvate oxidation, pyruvate => acetyl-CoA 0.999999999980346 -1.96536085461922e-11 5 0 0 28 7161 M00057 Glycosaminoglycan biosynthesis, linkage tetrasaccharide 0.999999999980346 -1.96536085461922e-11 5 0 0 28 7161 M00037 Melatonin biosynthesis, tryptophan => serotonin => melatonin 0.999999999980346 -1.96536085461922e-11 5 0 0 28 7161 hsa00232 Caffeine metabolism 0.999999999980346 -1.96536085461922e-11 5 0 0 28 7161 M00044 Tyrosine degradation, tyrosine => homogentisate 0.999999999980346 -1.96536085461922e-11 5 0 0 28 7161 M00383 ECV complex 0.999999999980346 -1.96536085461922e-11 5 0 0 28 7161 M00380 SCF-BTRC complex 0.999999999980346 -1.96536085461922e-11 5 0 0 28 7161 hsa_M00042 Catecholamine biosynthesis, tyrosine => dopamine => noradrenaline => adrenaline 0.999999999980346 -1.96536085461922e-11 5 0 0 28 7161 hsa_M00079 Keratan sulfate degradation 0.999999999980346 -1.96536085461922e-11 5 0 0 28 7161 hsa_M00380 SCF-BTRC complex 0.999999999980346 -1.96536085461922e-11 5 0 0 28 7161 hsa_M00128 Ubiquinone biosynthesis, eukaryotes, 4-hydroxybenzoate => ubiquinone 0.999999999980346 -1.96536085461922e-11 5 0 0 28 7161 ko00232 Caffeine metabolism 0.999999999980346 -1.96536085461922e-11 5 0 0 28 7161 M00414 Bloom's syndrome complex 0.999999999980346 -1.96536085461922e-11 5 0 0 28 7161 hsa_M00382 SCF-FBS complex 0.999999999980346 -1.96536085461922e-11 5 0 0 28 7161 M00289 RF-C complex 0.999999999980346 -1.96536085461922e-11 5 0 0 28 7161 M00382 SCF-FBS complex 0.999999999980346 -1.96536085461922e-11 5 0 0 28 7161 hsa_M00383 ECV complex 0.999999999980346 -1.96536085461922e-11 5 0 0 28 7161 hsa_M00044 Tyrosine degradation, tyrosine => homogentisate 0.999999999980346 -1.96536085461922e-11 5 0 0 28 7161 hsa_M00289 RF-C complex 0.999999999980346 -1.96536085461922e-11 5 0 0 28 7161 M00307 Pyruvate oxidation, pyruvate => acetyl-CoA 0.999999999980346 -1.96536085461922e-11 5 0 0 28 7161 M00071 Glycosphingolipid biosynthesis, neolacto-series, LacCer => nLc4Cer 0.999999999980346 -1.96536085461922e-11 5 0 0 28 7161 ko00400 Phenylalanine, tyrosine and tryptophan biosynthesis 0.999999999980346 -1.96536085461922e-11 5 0 0 28 7161 hsa_M00405 THC complex 0.999999999980346 -1.96536085461922e-11 5 0 0 28 7161 M00385 Cul4-DDB1-DDB2 complex 0.999999999980346 -1.96536085461922e-11 5 0 0 28 7161 hsa_M00386 Cul4-DDB1-CSA complex 0.999999999980346 -1.96536085461922e-11 5 0 0 28 7161 M00042 Catecholamine biosynthesis, tyrosine => dopamine => noradrenaline => adrenaline 0.999999999980346 -1.96536085461922e-11 5 0 0 28 7161 hsa00400 Phenylalanine, tyrosine and tryptophan biosynthesis 0.999999999980346 -1.96536085461922e-11 5 0 0 28 7161 hsa_M00385 Cul4-DDB1-DDB2 complex 0.999999999980346 -1.96536085461922e-11 5 0 0 28 7161 hsa_M00037 Melatonin biosynthesis, tryptophan => serotonin => melatonin 0.999999999980346 -1.96536085461922e-11 5 0 0 28 7161 M00386 Cul4-DDB1-CSA complex 0.999999999980346 -1.96536085461922e-11 5 0 0 28 7161 hsa_M00414 Bloom's syndrome complex 0.999999999980346 -1.96536085461922e-11 5 0 0 28 7161 M00079 Keratan sulfate degradation 0.999999999980346 -1.96536085461922e-11 5 0 0 28 7161 ko00524 Neomycin, kanamycin and gentamicin biosynthesis 0.999999999980346 -1.96536085461922e-11 5 0 0 28 7161 M00405 THC complex 0.999999999980346 -1.96536085461922e-11 5 0 0 28 7161 ko05224 Breast cancer 0.999999999980821 -1.91794588871112e-11 144 0 0 28 7161 hsa05224 Breast cancer 0.999999999980821 -1.91794588871112e-11 144 0 0 28 7161 ko00350 Tyrosine metabolism 0.999999999980921 -1.90791041495859e-11 35 0 0 28 7161 hsa00350 Tyrosine metabolism 0.999999999980921 -1.90791041495859e-11 35 0 0 28 7161 ko00250 Alanine, aspartate and glutamate metabolism 0.999999999980921 -1.90791041495859e-11 35 0 0 28 7161 hsa00250 Alanine, aspartate and glutamate metabolism 0.999999999980921 -1.90791041495859e-11 35 0 0 28 7161 hsa05213 Endometrial cancer 0.999999999981074 -1.89262382137694e-11 50 0 0 28 7161 ko05213 Endometrial cancer 0.999999999981074 -1.89262382137694e-11 50 0 0 28 7161 ko03030 DNA replication 0.999999999981099 -1.89007066789412e-11 36 0 0 28 7161 hsa00500 Starch and sucrose metabolism 0.999999999981099 -1.89007066789412e-11 36 0 0 28 7161 ko05340 Primary immunodeficiency 0.999999999981099 -1.89007066789412e-11 36 0 0 28 7161 hsa03030 DNA replication 0.999999999981099 -1.89007066789412e-11 36 0 0 28 7161 hsa05340 Primary immunodeficiency 0.999999999981099 -1.89007066789412e-11 36 0 0 28 7161 ko00500 Starch and sucrose metabolism 0.999999999981099 -1.89007066789412e-11 36 0 0 28 7161 hsa00534 Glycosaminoglycan biosynthesis - heparan sulfate / heparin 0.999999999981101 -1.88988190863512e-11 24 0 0 28 7161 hsa00340 Histidine metabolism 0.999999999981101 -1.88988190863512e-11 24 0 0 28 7161 ko00534 Glycosaminoglycan biosynthesis - heparan sulfate / heparin 0.999999999981101 -1.88988190863512e-11 24 0 0 28 7161 hsa_M00160 V-type ATPase, eukaryotes 0.999999999981101 -1.88988190863512e-11 24 0 0 28 7161 hsa04977 Vitamin digestion and absorption 0.999999999981101 -1.88988190863512e-11 24 0 0 28 7161 M00160 V-type ATPase, eukaryotes 0.999999999981101 -1.88988190863512e-11 24 0 0 28 7161 ko04977 Vitamin digestion and absorption 0.999999999981101 -1.88988190863512e-11 24 0 0 28 7161 ko00340 Histidine metabolism 0.999999999981101 -1.88988190863512e-11 24 0 0 28 7161 M00089 Triacylglycerol biosynthesis 0.999999999982318 -1.76823300296455e-11 17 0 0 28 7161 hsa00450 Selenocompound metabolism 0.999999999982318 -1.76823300296455e-11 17 0 0 28 7161 ko00910 Nitrogen metabolism 0.999999999982318 -1.76823300296455e-11 17 0 0 28 7161 hsa00360 Phenylalanine metabolism 0.999999999982318 -1.76823300296455e-11 17 0 0 28 7161 ko00360 Phenylalanine metabolism 0.999999999982318 -1.76823300296455e-11 17 0 0 28 7161 ko00450 Selenocompound metabolism 0.999999999982318 -1.76823300296455e-11 17 0 0 28 7161 hsa00120 Primary bile acid biosynthesis 0.999999999982318 -1.76823300296455e-11 17 0 0 28 7161 hsa_M00003 Gluconeogenesis, oxaloacetate => fructose-6P 0.999999999982318 -1.76823300296455e-11 17 0 0 28 7161 hsa_M00089 Triacylglycerol biosynthesis 0.999999999982318 -1.76823300296455e-11 17 0 0 28 7161 M00337 Immunoproteasome 0.999999999982318 -1.76823300296455e-11 17 0 0 28 7161 hsa_M00337 Immunoproteasome 0.999999999982318 -1.76823300296455e-11 17 0 0 28 7161 M00181 RNA polymerase III, eukaryotes 0.999999999982318 -1.76823300296455e-11 17 0 0 28 7161 hsa00910 Nitrogen metabolism 0.999999999982318 -1.76823300296455e-11 17 0 0 28 7161 ko00120 Primary bile acid biosynthesis 0.999999999982318 -1.76823300296455e-11 17 0 0 28 7161 hsa_M00181 RNA polymerase III, eukaryotes 0.999999999982318 -1.76823300296455e-11 17 0 0 28 7161 M00003 Gluconeogenesis, oxaloacetate => fructose-6P 0.999999999982318 -1.76823300296455e-11 17 0 0 28 7161 hsa00040 Pentose and glucuronate interconversions 0.999999999982389 -1.76109674712651e-11 34 0 0 28 7161 ko00040 Pentose and glucuronate interconversions 0.999999999982389 -1.76109674712651e-11 34 0 0 28 7161 hsa04130 SNARE interactions in vesicular transport 0.999999999982389 -1.76109674712651e-11 34 0 0 28 7161 ko04130 SNARE interactions in vesicular transport 0.999999999982389 -1.76109674712651e-11 34 0 0 28 7161 hsa05230 Central carbon metabolism in cancer 0.999999999982421 -1.75791300164852e-11 65 0 0 28 7161 ko05230 Central carbon metabolism in cancer 0.999999999982421 -1.75791300164852e-11 65 0 0 28 7161 ko00830 Retinol metabolism 0.999999999982421 -1.75791300164852e-11 65 0 0 28 7161 hsa00830 Retinol metabolism 0.999999999982421 -1.75791300164852e-11 65 0 0 28 7161 ko05222 Small cell lung cancer 0.999999999983936 -1.60642305098877e-11 84 0 0 28 7161 hsa05222 Small cell lung cancer 0.999999999983936 -1.60642305098877e-11 84 0 0 28 7161 hsa_M00632 Galactose degradation, Leloir pathway, galactose => alpha-D-glucose-1P 0.999999999984175 -1.58251059805358e-11 4 0 0 28 7161 hsa_M00690 MAPK (ERK5) signaling 0.999999999984175 -1.58251059805358e-11 4 0 0 28 7161 M00401 Sec61 complex 0.999999999984175 -1.58251059805358e-11 4 0 0 28 7161 M00015 Proline biosynthesis, glutamate => proline 0.999999999984175 -1.58251059805358e-11 4 0 0 28 7161 M00006 Pentose phosphate pathway, oxidative phase, glucose 6P => ribulose 5P 0.999999999984175 -1.58251059805358e-11 4 0 0 28 7161 hsa_M00741 Propanoyl-CoA metabolism, propanoyl-CoA => succinyl-CoA 0.999999999984175 -1.58251059805358e-11 4 0 0 28 7161 M00286 GINS complex 0.999999999984175 -1.58251059805358e-11 4 0 0 28 7161 hsa_M00006 Pentose phosphate pathway, oxidative phase, glucose 6P => ribulose 5P 0.999999999984175 -1.58251059805358e-11 4 0 0 28 7161 M00387 SCF-FBW7 complex 0.999999999984175 -1.58251059805358e-11 4 0 0 28 7161 M00741 Propanoyl-CoA metabolism, propanoyl-CoA => succinyl-CoA 0.999999999984175 -1.58251059805358e-11 4 0 0 28 7161 hsa_M00148 Succinate dehydrogenase (ubiquinone) 0.999999999984175 -1.58251059805358e-11 4 0 0 28 7161 M00263 DNA polymerase epsilon complex 0.999999999984175 -1.58251059805358e-11 4 0 0 28 7161 M00381 SCF-SKP2 complex 0.999999999984175 -1.58251059805358e-11 4 0 0 28 7161 M00148 Succinate dehydrogenase (ubiquinone) 0.999999999984175 -1.58251059805358e-11 4 0 0 28 7161 hsa00471 D-Glutamine and D-glutamate metabolism 0.999999999984175 -1.58251059805358e-11 4 0 0 28 7161 M00261 DNA polymerase alpha / primase complex 0.999999999984175 -1.58251059805358e-11 4 0 0 28 7161 M00110 C19/C18-Steroid hormone biosynthesis, pregnenolone => androstenedione => estrone 0.999999999984175 -1.58251059805358e-11 4 0 0 28 7161 hsa_M00288 RPA complex 0.999999999984175 -1.58251059805358e-11 4 0 0 28 7161 M00288 RPA complex 0.999999999984175 -1.58251059805358e-11 4 0 0 28 7161 M00425 H/ACA ribonucleoprotein complex 0.999999999984175 -1.58251059805358e-11 4 0 0 28 7161 hsa_M00387 SCF-FBW7 complex 0.999999999984175 -1.58251059805358e-11 4 0 0 28 7161 hsa_M00393 TRAMP complex 0.999999999984175 -1.58251059805358e-11 4 0 0 28 7161 hsa_M00384 Cul3-SPOP complex 0.999999999984175 -1.58251059805358e-11 4 0 0 28 7161 M00027 GABA (gamma-Aminobutyrate) shunt 0.999999999984175 -1.58251059805358e-11 4 0 0 28 7161 M00384 Cul3-SPOP complex 0.999999999984175 -1.58251059805358e-11 4 0 0 28 7161 hsa_M00685 Apoptotic machinery 0.999999999984175 -1.58251059805358e-11 4 0 0 28 7161 hsa_M00133 Polyamine biosynthesis, arginine => agmatine => putrescine => spermidine 0.999999999984175 -1.58251059805358e-11 4 0 0 28 7161 M00262 DNA polymerase delta complex 0.999999999984175 -1.58251059805358e-11 4 0 0 28 7161 M00685 Apoptotic machinery 0.999999999984175 -1.58251059805358e-11 4 0 0 28 7161 hsa_M00286 GINS complex 0.999999999984175 -1.58251059805358e-11 4 0 0 28 7161 hsa_M00390 Exosome, archaea 0.999999999984175 -1.58251059805358e-11 4 0 0 28 7161 M00402 Translocon-associated protein (TRAP) complex 0.999999999984175 -1.58251059805358e-11 4 0 0 28 7161 hsa_M00381 SCF-SKP2 complex 0.999999999984175 -1.58251059805358e-11 4 0 0 28 7161 M00390 Exosome, archaea 0.999999999984175 -1.58251059805358e-11 4 0 0 28 7161 M00632 Galactose degradation, Leloir pathway, galactose => alpha-D-glucose-1P 0.999999999984175 -1.58251059805358e-11 4 0 0 28 7161 M00393 TRAMP complex 0.999999999984175 -1.58251059805358e-11 4 0 0 28 7161 M00070 Glycosphingolipid biosynthesis, lacto-series, LacCer => Lc4Cer 0.999999999984175 -1.58251059805358e-11 4 0 0 28 7161 hsa_M00070 Glycosphingolipid biosynthesis, lacto-series, LacCer => Lc4Cer 0.999999999984175 -1.58251059805358e-11 4 0 0 28 7161 hsa_M00263 DNA polymerase epsilon complex 0.999999999984175 -1.58251059805358e-11 4 0 0 28 7161 hsa_M00401 Sec61 complex 0.999999999984175 -1.58251059805358e-11 4 0 0 28 7161 hsa_M00015 Proline biosynthesis, glutamate => proline 0.999999999984175 -1.58251059805358e-11 4 0 0 28 7161 hsa00290 Valine, leucine and isoleucine biosynthesis 0.999999999984175 -1.58251059805358e-11 4 0 0 28 7161 hsa_M00262 DNA polymerase delta complex 0.999999999984175 -1.58251059805358e-11 4 0 0 28 7161 hsa_M00027 GABA (gamma-Aminobutyrate) shunt 0.999999999984175 -1.58251059805358e-11 4 0 0 28 7161 hsa_M00402 Translocon-associated protein (TRAP) complex 0.999999999984175 -1.58251059805358e-11 4 0 0 28 7161 ko00471 D-Glutamine and D-glutamate metabolism 0.999999999984175 -1.58251059805358e-11 4 0 0 28 7161 M00133 Polyamine biosynthesis, arginine => agmatine => putrescine => spermidine 0.999999999984175 -1.58251059805358e-11 4 0 0 28 7161 M00690 MAPK (ERK5) signaling 0.999999999984175 -1.58251059805358e-11 4 0 0 28 7161 ko00290 Valine, leucine and isoleucine biosynthesis 0.999999999984175 -1.58251059805358e-11 4 0 0 28 7161 hsa_M00425 H/ACA ribonucleoprotein complex 0.999999999984175 -1.58251059805358e-11 4 0 0 28 7161 hsa_M00261 DNA polymerase alpha / primase complex 0.999999999984175 -1.58251059805358e-11 4 0 0 28 7161 hsa_M00110 C19/C18-Steroid hormone biosynthesis, pregnenolone => androstenedione => estrone 0.999999999984175 -1.58251059805358e-11 4 0 0 28 7161 hsa_M00430 Exon junction complex (EJC) 0.999999999984221 -1.57786944961079e-11 18 0 0 28 7161 hsa01210 2-Oxocarboxylic acid metabolism 0.999999999984221 -1.57786944961079e-11 18 0 0 28 7161 ko01210 2-Oxocarboxylic acid metabolism 0.999999999984221 -1.57786944961079e-11 18 0 0 28 7161 ko00770 Pantothenate and CoA biosynthesis 0.999999999984221 -1.57786944961079e-11 18 0 0 28 7161 hsa00511 Other glycan degradation 0.999999999984221 -1.57786944961079e-11 18 0 0 28 7161 ko00511 Other glycan degradation 0.999999999984221 -1.57786944961079e-11 18 0 0 28 7161 hsa00770 Pantothenate and CoA biosynthesis 0.999999999984221 -1.57786944961079e-11 18 0 0 28 7161 M00430 Exon junction complex (EJC) 0.999999999984221 -1.57786944961079e-11 18 0 0 28 7161 hsa05332 Graft-versus-host disease 0.999999999984357 -1.56429761738463e-11 41 0 0 28 7161 ko05219 Bladder cancer 0.999999999984357 -1.56429761738463e-11 41 0 0 28 7161 hsa05219 Bladder cancer 0.999999999984357 -1.56429761738463e-11 41 0 0 28 7161 ko03440 Homologous recombination 0.999999999984357 -1.56429761738463e-11 41 0 0 28 7161 hsa03440 Homologous recombination 0.999999999984357 -1.56429761738463e-11 41 0 0 28 7161 ko05332 Graft-versus-host disease 0.999999999984357 -1.56429761738463e-11 41 0 0 28 7161 ko00512 Mucin type O-glycan biosynthesis 0.999999999984651 -1.53488785989633e-11 31 0 0 28 7161 ko00052 Galactose metabolism 0.999999999984651 -1.53488785989633e-11 31 0 0 28 7161 hsa01523 Antifolate resistance 0.999999999984651 -1.53488785989633e-11 31 0 0 28 7161 ko01523 Antifolate resistance 0.999999999984651 -1.53488785989633e-11 31 0 0 28 7161 hsa00410 beta-Alanine metabolism 0.999999999984651 -1.53488785989633e-11 31 0 0 28 7161 hsa03020 RNA polymerase 0.999999999984651 -1.53488785989633e-11 31 0 0 28 7161 ko00410 beta-Alanine metabolism 0.999999999984651 -1.53488785989633e-11 31 0 0 28 7161 hsa00052 Galactose metabolism 0.999999999984651 -1.53488785989633e-11 31 0 0 28 7161 ko03020 RNA polymerase 0.999999999984651 -1.53488785989633e-11 31 0 0 28 7161 hsa00512 Mucin type O-glycan biosynthesis 0.999999999984651 -1.53488785989633e-11 31 0 0 28 7161 M00359 Aminoacyl-tRNA biosynthesis, eukaryotes 0.999999999984689 -1.53108308335186e-11 38 0 0 28 7161 hsa_M00359 Aminoacyl-tRNA biosynthesis, eukaryotes 0.999999999984689 -1.53108308335186e-11 38 0 0 28 7161 M00677 Wnt signaling 0.999999999984689 -1.53108308335186e-11 38 0 0 28 7161 hsa_M00677 Wnt signaling 0.999999999984689 -1.53108308335186e-11 38 0 0 28 7161 hsa00564 Glycerophospholipid metabolism 0.999999999984886 -1.51140532583268e-11 95 0 0 28 7161 ko00564 Glycerophospholipid metabolism 0.999999999984886 -1.51140532583268e-11 95 0 0 28 7161 hsa00480 Glutathione metabolism 0.99999999998501 -1.49897139032541e-11 54 0 0 28 7161 ko03460 Fanconi anemia pathway 0.99999999998501 -1.49897139032541e-11 54 0 0 28 7161 ko00480 Glutathione metabolism 0.99999999998501 -1.49897139032541e-11 54 0 0 28 7161 hsa03460 Fanconi anemia pathway 0.99999999998501 -1.49897139032541e-11 54 0 0 28 7161 hsa00600 Sphingolipid metabolism 0.999999999985445 -1.45545959131557e-11 47 0 0 28 7161 ko03420 Nucleotide excision repair 0.999999999985445 -1.45545959131557e-11 47 0 0 28 7161 hsa04672 Intestinal immune network for IgA production 0.999999999985445 -1.45545959131557e-11 47 0 0 28 7161 ko04340 Hedgehog signaling pathway 0.999999999985445 -1.45545959131557e-11 47 0 0 28 7161 ko00600 Sphingolipid metabolism 0.999999999985445 -1.45545959131557e-11 47 0 0 28 7161 ko04672 Intestinal immune network for IgA production 0.999999999985445 -1.45545959131557e-11 47 0 0 28 7161 hsa04340 Hedgehog signaling pathway 0.999999999985445 -1.45545959131557e-11 47 0 0 28 7161 hsa03420 Nucleotide excision repair 0.999999999985445 -1.45545959131557e-11 47 0 0 28 7161 ko04662 B cell receptor signaling pathway 0.999999999985474 -1.45255725075381e-11 70 0 0 28 7161 hsa04662 B cell receptor signaling pathway 0.999999999985474 -1.45255725075381e-11 70 0 0 28 7161 hsa05100 Bacterial invasion of epithelial cells 0.999999999985753 -1.42469336493472e-11 76 0 0 28 7161 ko05100 Bacterial invasion of epithelial cells 0.999999999985753 -1.42469336493472e-11 76 0 0 28 7161 hsa05412 Arrhythmogenic right ventricular cardiomyopathy (ARVC) 0.999999999986048 -1.39522704538261e-11 72 0 0 28 7161 ko05140 Leishmaniasis 0.999999999986048 -1.39522704538261e-11 72 0 0 28 7161 ko05412 Arrhythmogenic right ventricular cardiomyopathy (ARVC) 0.999999999986048 -1.39522704538261e-11 72 0 0 28 7161 hsa05140 Leishmaniasis 0.999999999986048 -1.39522704538261e-11 72 0 0 28 7161 hsa00240 Pyrimidine metabolism 0.999999999986559 -1.34406142114654e-11 104 0 0 28 7161 ko00240 Pyrimidine metabolism 0.999999999986559 -1.34406142114654e-11 104 0 0 28 7161 hsa04614 Renin-angiotensin system 0.999999999986627 -1.337274683479e-11 23 0 0 28 7161 ko04614 Renin-angiotensin system 0.999999999986627 -1.337274683479e-11 23 0 0 28 7161 hsa01040 Biosynthesis of unsaturated fatty acids 0.999999999986627 -1.337274683479e-11 23 0 0 28 7161 ko00515 Mannose type O-glycan biosynthesis 0.999999999986627 -1.337274683479e-11 23 0 0 28 7161 hsa00515 Mannose type O-glycan biosynthesis 0.999999999986627 -1.337274683479e-11 23 0 0 28 7161 ko01040 Biosynthesis of unsaturated fatty acids 0.999999999986627 -1.337274683479e-11 23 0 0 28 7161 ko03060 Protein export 0.999999999986627 -1.337274683479e-11 23 0 0 28 7161 ko03430 Mismatch repair 0.999999999986627 -1.337274683479e-11 23 0 0 28 7161 hsa03430 Mismatch repair 0.999999999986627 -1.337274683479e-11 23 0 0 28 7161 hsa03060 Protein export 0.999999999986627 -1.337274683479e-11 23 0 0 28 7161 M00340 Proteasome, 20S core particle 0.999999999986951 -1.3048881294401e-11 15 0 0 28 7161 hsa_M00340 Proteasome, 20S core particle 0.999999999986951 -1.3048881294401e-11 15 0 0 28 7161 ko00790 Folate biosynthesis 0.999999999986951 -1.3048881294401e-11 15 0 0 28 7161 ko00730 Thiamine metabolism 0.999999999986951 -1.3048881294401e-11 15 0 0 28 7161 M00146 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex 0.999999999986951 -1.3048881294401e-11 15 0 0 28 7161 M00158 F-type ATPase, eukaryotes 0.999999999986951 -1.3048881294401e-11 15 0 0 28 7161 hsa_M00686 Toll-like receptor signaling 0.999999999986951 -1.3048881294401e-11 15 0 0 28 7161 hsa00790 Folate biosynthesis 0.999999999986951 -1.3048881294401e-11 15 0 0 28 7161 hsa00730 Thiamine metabolism 0.999999999986951 -1.3048881294401e-11 15 0 0 28 7161 hsa_M00146 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex 0.999999999986951 -1.3048881294401e-11 15 0 0 28 7161 M00686 Toll-like receptor signaling 0.999999999986951 -1.3048881294401e-11 15 0 0 28 7161 hsa_M00158 F-type ATPase, eukaryotes 0.999999999986951 -1.3048881294401e-11 15 0 0 28 7161 ko00604 Glycosphingolipid biosynthesis - ganglio series 0.999999999986951 -1.3048881294401e-11 15 0 0 28 7161 hsa00603 Glycosphingolipid biosynthesis - globo and isoglobo series 0.999999999986951 -1.3048881294401e-11 15 0 0 28 7161 hsa00604 Glycosphingolipid biosynthesis - ganglio series 0.999999999986951 -1.3048881294401e-11 15 0 0 28 7161 ko00640 Propanoate metabolism 0.999999999987075 -1.29248652300523e-11 32 0 0 28 7161 ko04136 Autophagy - other 0.999999999987075 -1.29248652300523e-11 32 0 0 28 7161 hsa04136 Autophagy - other 0.999999999987075 -1.29248652300523e-11 32 0 0 28 7161 hsa00640 Propanoate metabolism 0.999999999987075 -1.29248652300523e-11 32 0 0 28 7161 hsa00472 D-Arginine and D-ornithine metabolism 0.999999999987255 -1.27449110293165e-11 1 0 0 28 7161 hsa_M00043 Thyroid hormone biosynthesis, tyrosine => triiodothyronine/thyroxine 0.999999999987255 -1.27449110293165e-11 1 0 0 28 7161 M00043 Thyroid hormone biosynthesis, tyrosine => triiodothyronine/thyroxine 0.999999999987255 -1.27449110293165e-11 1 0 0 28 7161 ko00472 D-Arginine and D-ornithine metabolism 0.999999999987255 -1.27449110293165e-11 1 0 0 28 7161 hsa_M00091 Phosphatidylcholine (PC) biosynthesis, PE => PC 0.999999999987255 -1.27449110293165e-11 1 0 0 28 7161 M00091 Phosphatidylcholine (PC) biosynthesis, PE => PC 0.999999999987255 -1.27449110293165e-11 1 0 0 28 7161 ko04940 Type I diabetes mellitus 0.999999999987261 -1.27394458374753e-11 43 0 0 28 7161 hsa04940 Type I diabetes mellitus 0.999999999987261 -1.27394458374753e-11 43 0 0 28 7161 hsa00591 Linoleic acid metabolism 0.999999999987391 -1.2609169393537e-11 29 0 0 28 7161 hsa04392 Hippo signaling pathway -multiple species 0.999999999987391 -1.2609169393537e-11 29 0 0 28 7161 hsa00760 Nicotinate and nicotinamide metabolism 0.999999999987391 -1.2609169393537e-11 29 0 0 28 7161 hsa05216 Thyroid cancer 0.999999999987391 -1.2609169393537e-11 29 0 0 28 7161 ko00760 Nicotinate and nicotinamide metabolism 0.999999999987391 -1.2609169393537e-11 29 0 0 28 7161 ko04392 Hippo signaling pathway -multiple species 0.999999999987391 -1.2609169393537e-11 29 0 0 28 7161 ko05216 Thyroid cancer 0.999999999987391 -1.2609169393537e-11 29 0 0 28 7161 ko00591 Linoleic acid metabolism 0.999999999987391 -1.2609169393537e-11 29 0 0 28 7161 ko00260 Glycine, serine and threonine metabolism 0.999999999988001 -1.19988408518383e-11 39 0 0 28 7161 hsa00260 Glycine, serine and threonine metabolism 0.999999999988001 -1.19988408518383e-11 39 0 0 28 7161 hsa00620 Pyruvate metabolism 0.999999999988001 -1.19988408518383e-11 39 0 0 28 7161 ko00620 Pyruvate metabolism 0.999999999988001 -1.19988408518383e-11 39 0 0 28 7161 hsa04142 Lysosome 0.999999999988075 -1.19254019218488e-11 123 0 0 28 7161 ko04142 Lysosome 0.999999999988075 -1.19254019218488e-11 123 0 0 28 7161 hsa_M00293 DNA polymerase zeta complex 0.999999999988167 -1.18331051151378e-11 2 0 0 28 7161 M00294 DNA polymerase gamma complex 0.999999999988167 -1.18331051151378e-11 2 0 0 28 7161 M00103 Cholecalciferol biosynthesis 0.999999999988167 -1.18331051151378e-11 2 0 0 28 7161 M00068 Glycosphingolipid biosynthesis, globo-series, LacCer => Gb4Cer 0.999999999988167 -1.18331051151378e-11 2 0 0 28 7161 hsa_M00083 Fatty acid biosynthesis, elongation 0.999999999988167 -1.18331051151378e-11 2 0 0 28 7161 hsa_M00399 Cap binding complex 0.999999999988167 -1.18331051151378e-11 2 0 0 28 7161 hsa_M00338 Cysteine biosynthesis, homocysteine + serine => cysteine 0.999999999988167 -1.18331051151378e-11 2 0 0 28 7161 M00293 DNA polymerase zeta complex 0.999999999988167 -1.18331051151378e-11 2 0 0 28 7161 hsa_M00554 Nucleotide sugar biosynthesis, galactose => UDP-galactose 0.999999999988167 -1.18331051151378e-11 2 0 0 28 7161 M00083 Fatty acid biosynthesis, elongation 0.999999999988167 -1.18331051151378e-11 2 0 0 28 7161 hsa_M00066 Lactosylceramide biosynthesis 0.999999999988167 -1.18331051151378e-11 2 0 0 28 7161 M00066 Lactosylceramide biosynthesis 0.999999999988167 -1.18331051151378e-11 2 0 0 28 7161 hsa_M00151 Cytochrome bc1 complex respiratory unit 0.999999999988167 -1.18331051151378e-11 2 0 0 28 7161 hsa00300 Lysine biosynthesis 0.999999999988167 -1.18331051151378e-11 2 0 0 28 7161 hsa_M00106 Conjugated bile acid biosynthesis, cholate => taurocholate/glycocholate 0.999999999988167 -1.18331051151378e-11 2 0 0 28 7161 M00554 Nucleotide sugar biosynthesis, galactose => UDP-galactose 0.999999999988167 -1.18331051151378e-11 2 0 0 28 7161 M00067 Sulfoglycolipids biosynthesis, ceramide/1-alkyl-2-acylglycerol => sulfatide/seminolipid 0.999999999988167 -1.18331051151378e-11 2 0 0 28 7161 hsa_M00103 Cholecalciferol biosynthesis 0.999999999988167 -1.18331051151378e-11 2 0 0 28 7161 M00106 Conjugated bile acid biosynthesis, cholate => taurocholate/glycocholate 0.999999999988167 -1.18331051151378e-11 2 0 0 28 7161 hsa_M00294 DNA polymerase gamma complex 0.999999999988167 -1.18331051151378e-11 2 0 0 28 7161 M00338 Cysteine biosynthesis, homocysteine + serine => cysteine 0.999999999988167 -1.18331051151378e-11 2 0 0 28 7161 hsa_M00068 Glycosphingolipid biosynthesis, globo-series, LacCer => Gb4Cer 0.999999999988167 -1.18331051151378e-11 2 0 0 28 7161 ko00300 Lysine biosynthesis 0.999999999988167 -1.18331051151378e-11 2 0 0 28 7161 M00399 Cap binding complex 0.999999999988167 -1.18331051151378e-11 2 0 0 28 7161 hsa_M00067 Sulfoglycolipids biosynthesis, ceramide/1-alkyl-2-acylglycerol => sulfatide/seminolipid 0.999999999988167 -1.18331051151378e-11 2 0 0 28 7161 M00151 Cytochrome bc1 complex respiratory unit 0.999999999988167 -1.18331051151378e-11 2 0 0 28 7161 ko05330 Allograft rejection 0.99999999998893 -1.1069942378299e-11 37 0 0 28 7161 hsa_M00355 Spliceosome, 35S U5-snRNP 0.99999999998893 -1.1069942378299e-11 37 0 0 28 7161 hsa05330 Allograft rejection 0.99999999998893 -1.1069942378299e-11 37 0 0 28 7161 M00355 Spliceosome, 35S U5-snRNP 0.99999999998893 -1.1069942378299e-11 37 0 0 28 7161 ko04721 Synaptic vesicle cycle 0.999999999989147 -1.08531088487296e-11 63 0 0 28 7161 hsa04721 Synaptic vesicle cycle 0.999999999989147 -1.08531088487296e-11 63 0 0 28 7161 hsa04623 Cytosolic DNA-sensing pathway 0.999999999989147 -1.08531088487296e-11 63 0 0 28 7161 ko04623 Cytosolic DNA-sensing pathway 0.999999999989147 -1.08531088487296e-11 63 0 0 28 7161 hsa05203 Viral carcinogenesis 0.999999999989289 -1.07111679504437e-11 201 0 0 28 7161 ko05203 Viral carcinogenesis 0.999999999989289 -1.07111679504437e-11 201 0 0 28 7161 ko05320 Autoimmune thyroid disease 0.999999999989471 -1.05285887567022e-11 52 0 0 28 7161 hsa05320 Autoimmune thyroid disease 0.999999999989471 -1.05285887567022e-11 52 0 0 28 7161 M00107 Steroid hormone biosynthesis, cholesterol => prognenolone => progesterone 0.999999999989481 -1.05185391946824e-11 3 0 0 28 7161 hsa_M00046 Pyrimidine degradation, uracil => beta-alanine, thymine => 3-aminoisobutanoate 0.999999999989481 -1.05185391946824e-11 3 0 0 28 7161 M00400 p97-Ufd1-Npl4 complex 0.999999999989481 -1.05185391946824e-11 3 0 0 28 7161 hsa_M00005 PRPP biosynthesis, ribose 5P => PRPP 0.999999999989481 -1.05185391946824e-11 3 0 0 28 7161 hsa_M00408 ESCRT-0 complex 0.999999999989481 -1.05185391946824e-11 3 0 0 28 7161 hsa_M00400 p97-Ufd1-Npl4 complex 0.999999999989481 -1.05185391946824e-11 3 0 0 28 7161 M00392 Ski complex 0.999999999989481 -1.05185391946824e-11 3 0 0 28 7161 hsa_M00107 Steroid hormone biosynthesis, cholesterol => prognenolone => progesterone 0.999999999989481 -1.05185391946824e-11 3 0 0 28 7161 M00100 Sphingosine degradation 0.999999999989481 -1.05185391946824e-11 3 0 0 28 7161 hsa00785 Lipoic acid metabolism 0.999999999989481 -1.05185391946824e-11 3 0 0 28 7161 M00410 ESCRT-II complex 0.999999999989481 -1.05185391946824e-11 3 0 0 28 7161 M00051 Uridine monophosphate biosynthesis, glutamine (+ PRPP) => UMP 0.999999999989481 -1.05185391946824e-11 3 0 0 28 7161 hsa_M00100 Sphingosine degradation 0.999999999989481 -1.05185391946824e-11 3 0 0 28 7161 hsa_M00082 Fatty acid biosynthesis, initiation 0.999999999989481 -1.05185391946824e-11 3 0 0 28 7161 ko00785 Lipoic acid metabolism 0.999999999989481 -1.05185391946824e-11 3 0 0 28 7161 hsa_M00291 MRN complex 0.999999999989481 -1.05185391946824e-11 3 0 0 28 7161 hsa_M00108 C21-Steroid hormone biosynthesis, progesterone => corticosterone/aldosterone 0.999999999989481 -1.05185391946824e-11 3 0 0 28 7161 M00005 PRPP biosynthesis, ribose 5P => PRPP 0.999999999989481 -1.05185391946824e-11 3 0 0 28 7161 hsa_M00134 Polyamine biosynthesis, arginine => ornithine => putrescine 0.999999999989481 -1.05185391946824e-11 3 0 0 28 7161 hsa_M00392 Ski complex 0.999999999989481 -1.05185391946824e-11 3 0 0 28 7161 M00132 Inositol phosphate metabolism, Ins(1,3,4)P3 => phytate 0.999999999989481 -1.05185391946824e-11 3 0 0 28 7161 hsa_M00069 Glycosphingolipid biosynthesis, ganglio series, LacCer => GT3 0.999999999989481 -1.05185391946824e-11 3 0 0 28 7161 M00297 DNA-PK complex 0.999999999989481 -1.05185391946824e-11 3 0 0 28 7161 hsa00780 Biotin metabolism 0.999999999989481 -1.05185391946824e-11 3 0 0 28 7161 M00291 MRN complex 0.999999999989481 -1.05185391946824e-11 3 0 0 28 7161 M00020 Serine biosynthesis, glycerate-3P => serine 0.999999999989481 -1.05185391946824e-11 3 0 0 28 7161 M00408 ESCRT-0 complex 0.999999999989481 -1.05185391946824e-11 3 0 0 28 7161 hsa_M00132 Inositol phosphate metabolism, Ins(1,3,4)P3 => phytate 0.999999999989481 -1.05185391946824e-11 3 0 0 28 7161 M00108 C21-Steroid hormone biosynthesis, progesterone => corticosterone/aldosterone 0.999999999989481 -1.05185391946824e-11 3 0 0 28 7161 M00134 Polyamine biosynthesis, arginine => ornithine => putrescine 0.999999999989481 -1.05185391946824e-11 3 0 0 28 7161 M00046 Pyrimidine degradation, uracil => beta-alanine, thymine => 3-aminoisobutanoate 0.999999999989481 -1.05185391946824e-11 3 0 0 28 7161 M00118 Glutathione biosynthesis, glutamate => glutathione 0.999999999989481 -1.05185391946824e-11 3 0 0 28 7161 hsa_M00410 ESCRT-II complex 0.999999999989481 -1.05185391946824e-11 3 0 0 28 7161 hsa_M00297 DNA-PK complex 0.999999999989481 -1.05185391946824e-11 3 0 0 28 7161 M00082 Fatty acid biosynthesis, initiation 0.999999999989481 -1.05185391946824e-11 3 0 0 28 7161 ko00780 Biotin metabolism 0.999999999989481 -1.05185391946824e-11 3 0 0 28 7161 M00069 Glycosphingolipid biosynthesis, ganglio series, LacCer => GT3 0.999999999989481 -1.05185391946824e-11 3 0 0 28 7161 hsa_M00118 Glutathione biosynthesis, glutamate => glutathione 0.999999999989481 -1.05185391946824e-11 3 0 0 28 7161 hsa_M00051 Uridine monophosphate biosynthesis, glutamine (+ PRPP) => UMP 0.999999999989481 -1.05185391946824e-11 3 0 0 28 7161 hsa_M00020 Serine biosynthesis, glycerate-3P => serine 0.999999999989481 -1.05185391946824e-11 3 0 0 28 7161 hsa05202 Transcriptional misregulation in cancer 0.999999999989664 -1.03363990604805e-11 179 0 0 28 7161 ko05202 Transcriptional misregulation in cancer 0.999999999989664 -1.03363990604805e-11 179 0 0 28 7161 M00341 Proteasome, 19S regulatory particle (PA700) 0.999999999989817 -1.01825185454108e-11 19 0 0 28 7161 M00684 JAK-STAT signaling 0.999999999989817 -1.01825185454108e-11 19 0 0 28 7161 hsa_M00341 Proteasome, 19S regulatory particle (PA700) 0.999999999989817 -1.01825185454108e-11 19 0 0 28 7161 hsa_M00684 JAK-STAT signaling 0.999999999989817 -1.01825185454108e-11 19 0 0 28 7161 ko00062 Fatty acid elongation 0.999999999989891 -1.01088034732408e-11 25 0 0 28 7161 hsa00592 alpha-Linolenic acid metabolism 0.999999999989891 -1.01088034732408e-11 25 0 0 28 7161 hsa00563 Glycosylphosphatidylinositol (GPI)-anchor biosynthesis 0.999999999989891 -1.01088034732408e-11 25 0 0 28 7161 hsa_M00001 Glycolysis (Embden-Meyerhof pathway), glucose => pyruvate 0.999999999989891 -1.01088034732408e-11 25 0 0 28 7161 ko00592 alpha-Linolenic acid metabolism 0.999999999989891 -1.01088034732408e-11 25 0 0 28 7161 hsa00062 Fatty acid elongation 0.999999999989891 -1.01088034732408e-11 25 0 0 28 7161 ko00563 Glycosylphosphatidylinositol (GPI)-anchor biosynthesis 0.999999999989891 -1.01088034732408e-11 25 0 0 28 7161 M00001 Glycolysis (Embden-Meyerhof pathway), glucose => pyruvate 0.999999999989891 -1.01088034732408e-11 25 0 0 28 7161 ko00533 Glycosaminoglycan biosynthesis - keratan sulfate 0.999999999989894 -1.01063505059552e-11 14 0 0 28 7161 hsa_M00147 NADH dehydrogenase (ubiquinone) 1 beta subcomplex 0.999999999989894 -1.01063505059552e-11 14 0 0 28 7161 hsa00533 Glycosaminoglycan biosynthesis - keratan sulfate 0.999999999989894 -1.01063505059552e-11 14 0 0 28 7161 M00353 Spliceosome, Prp19/CDC5L complex 0.999999999989894 -1.01063505059552e-11 14 0 0 28 7161 hsa_M00180 RNA polymerase II, eukaryotes 0.999999999989894 -1.01063505059552e-11 14 0 0 28 7161 M00389 APC/C complex 0.999999999989894 -1.01063505059552e-11 14 0 0 28 7161 hsa_M00353 Spliceosome, Prp19/CDC5L complex 0.999999999989894 -1.01063505059552e-11 14 0 0 28 7161 hsa_M00055 N-glycan precursor biosynthesis 0.999999999989894 -1.01063505059552e-11 14 0 0 28 7161 M00180 RNA polymerase II, eukaryotes 0.999999999989894 -1.01063505059552e-11 14 0 0 28 7161 M00147 NADH dehydrogenase (ubiquinone) 1 beta subcomplex 0.999999999989894 -1.01063505059552e-11 14 0 0 28 7161 hsa_M00011 Citrate cycle, second carbon oxidation, 2-oxoglutarate => oxaloacetate 0.999999999989894 -1.01063505059552e-11 14 0 0 28 7161 M00055 N-glycan precursor biosynthesis 0.999999999989894 -1.01063505059552e-11 14 0 0 28 7161 M00011 Citrate cycle, second carbon oxidation, 2-oxoglutarate => oxaloacetate 0.999999999989894 -1.01063505059552e-11 14 0 0 28 7161 hsa_M00389 APC/C complex 0.999999999989894 -1.01063505059552e-11 14 0 0 28 7161 hsa00561 Glycerolipid metabolism 0.999999999989963 -1.00366430920985e-11 59 0 0 28 7161 ko00561 Glycerolipid metabolism 0.999999999989963 -1.00366430920985e-11 59 0 0 28 7161 hsa00310 Lysine degradation 0.999999999989963 -1.00366430920985e-11 59 0 0 28 7161 ko00310 Lysine degradation 0.999999999989963 -1.00366430920985e-11 59 0 0 28 7161 ko03022 Basal transcription factors 0.999999999990116 -9.88427413378203e-12 45 0 0 28 7161 hsa03022 Basal transcription factors 0.999999999990116 -9.88427413378203e-12 45 0 0 28 7161 hsa_M00427 Nuclear pore complex 0.999999999990116 -9.88427413378203e-12 45 0 0 28 7161 ko03050 Proteasome 0.999999999990116 -9.88427413378203e-12 45 0 0 28 7161 hsa00565 Ether lipid metabolism 0.999999999990116 -9.88427413378203e-12 45 0 0 28 7161 M00427 Nuclear pore complex 0.999999999990116 -9.88427413378203e-12 45 0 0 28 7161 hsa03050 Proteasome 0.999999999990116 -9.88427413378203e-12 45 0 0 28 7161 ko00565 Ether lipid metabolism 0.999999999990116 -9.88427413378203e-12 45 0 0 28 7161 ko00220 Arginine biosynthesis 0.999999999990531 -9.46855191150495e-12 21 0 0 28 7161 M00049 Adenine ribonucleotide biosynthesis, IMP => ADP,ATP 0.999999999990531 -9.46855191150495e-12 21 0 0 28 7161 hsa_M00049 Adenine ribonucleotide biosynthesis, IMP => ADP,ATP 0.999999999990531 -9.46855191150495e-12 21 0 0 28 7161 hsa_M00154 Cytochrome c oxidase 0.999999999990531 -9.46855191150495e-12 21 0 0 28 7161 M00154 Cytochrome c oxidase 0.999999999990531 -9.46855191150495e-12 21 0 0 28 7161 hsa00220 Arginine biosynthesis 0.999999999990531 -9.46855191150495e-12 21 0 0 28 7161 ko04330 Notch signaling pathway 0.99999999999057 -9.43050550472894e-12 48 0 0 28 7161 ko00280 Valine, leucine and isoleucine degradation 0.99999999999057 -9.43050550472894e-12 48 0 0 28 7161 ko00520 Amino sugar and nucleotide sugar metabolism 0.99999999999057 -9.43050550472894e-12 48 0 0 28 7161 hsa01212 Fatty acid metabolism 0.99999999999057 -9.43050550472894e-12 48 0 0 28 7161 hsa00520 Amino sugar and nucleotide sugar metabolism 0.99999999999057 -9.43050550472894e-12 48 0 0 28 7161 ko01212 Fatty acid metabolism 0.99999999999057 -9.43050550472894e-12 48 0 0 28 7161 hsa04330 Notch signaling pathway 0.99999999999057 -9.43050550472894e-12 48 0 0 28 7161 hsa00280 Valine, leucine and isoleucine degradation 0.99999999999057 -9.43050550472894e-12 48 0 0 28 7161 ko00983 Drug metabolism - other enzymes 0.999999999990672 -9.32781051446403e-12 46 0 0 28 7161 hsa00983 Drug metabolism - other enzymes 0.999999999990672 -9.32781051446403e-12 46 0 0 28 7161 ko03040 Spliceosome 0.999999999990727 -9.27292427176222e-12 132 0 0 28 7161 hsa05322 Systemic lupus erythematosus 0.999999999990727 -9.27292427176222e-12 132 0 0 28 7161 ko05322 Systemic lupus erythematosus 0.999999999990727 -9.27292427176222e-12 132 0 0 28 7161 hsa03040 Spliceosome 0.999999999990727 -9.27292427176222e-12 132 0 0 28 7161 hsa04744 Phototransduction 0.999999999990733 -9.26677140194728e-12 28 0 0 28 7161 ko04744 Phototransduction 0.999999999990733 -9.26677140194728e-12 28 0 0 28 7161 ko00630 Glyoxylate and dicarboxylate metabolism 0.999999999990733 -9.26677140194728e-12 28 0 0 28 7161 ko00650 Butanoate metabolism 0.999999999990733 -9.26677140194728e-12 28 0 0 28 7161 hsa00650 Butanoate metabolism 0.999999999990733 -9.26677140194728e-12 28 0 0 28 7161 hsa00630 Glyoxylate and dicarboxylate metabolism 0.999999999990733 -9.26677140194728e-12 28 0 0 28 7161 ko00010 Glycolysis / Gluconeogenesis 0.999999999991023 -8.97668587661589e-12 67 0 0 28 7161 hsa00010 Glycolysis / Gluconeogenesis 0.999999999991023 -8.97668587661589e-12 67 0 0 28 7161 M00403 HRD1/SEL1 ERAD complex 0.99999999999118 -8.8202753261962e-12 13 0 0 28 7161 M00050 Guanine ribonucleotide biosynthesis IMP => GDP,GTP 0.99999999999118 -8.8202753261962e-12 13 0 0 28 7161 hsa_M00050 Guanine ribonucleotide biosynthesis IMP => GDP,GTP 0.99999999999118 -8.8202753261962e-12 13 0 0 28 7161 ko03450 Non-homologous end-joining 0.99999999999118 -8.8202753261962e-12 13 0 0 28 7161 M00692 Cell cycle - G1/S transition 0.99999999999118 -8.8202753261962e-12 13 0 0 28 7161 M00676 PI3K-Akt signaling 0.99999999999118 -8.8202753261962e-12 13 0 0 28 7161 hsa_M00036 Leucine degradation, leucine => acetoacetate + acetyl-CoA 0.99999999999118 -8.8202753261962e-12 13 0 0 28 7161 hsa_M00676 PI3K-Akt signaling 0.99999999999118 -8.8202753261962e-12 13 0 0 28 7161 hsa_M00415 Fatty acid biosynthesis, elongation, endoplasmic reticulum 0.99999999999118 -8.8202753261962e-12 13 0 0 28 7161 ko00061 Fatty acid biosynthesis 0.99999999999118 -8.8202753261962e-12 13 0 0 28 7161 hsa00061 Fatty acid biosynthesis 0.99999999999118 -8.8202753261962e-12 13 0 0 28 7161 M00415 Fatty acid biosynthesis, elongation, endoplasmic reticulum 0.99999999999118 -8.8202753261962e-12 13 0 0 28 7161 hsa_M00692 Cell cycle - G1/S transition 0.99999999999118 -8.8202753261962e-12 13 0 0 28 7161 M00036 Leucine degradation, leucine => acetoacetate + acetyl-CoA 0.99999999999118 -8.8202753261962e-12 13 0 0 28 7161 hsa03450 Non-homologous end-joining 0.99999999999118 -8.8202753261962e-12 13 0 0 28 7161 hsa_M00403 HRD1/SEL1 ERAD complex 0.99999999999118 -8.8202753261962e-12 13 0 0 28 7161 M00135 GABA biosynthesis, eukaryotes, putrescine => GABA 0.999999999991423 -8.57743822823157e-12 9 0 0 28 7161 hsa_M00694 cGMP signaling 0.999999999991423 -8.57743822823157e-12 9 0 0 28 7161 M00076 Dermatan sulfate degradation 0.999999999991423 -8.57743822823157e-12 9 0 0 28 7161 hsa_M00076 Dermatan sulfate degradation 0.999999999991423 -8.57743822823157e-12 9 0 0 28 7161 hsa_M00361 Nucleotide sugar biosynthesis, eukaryotes 0.999999999991423 -8.57743822823157e-12 9 0 0 28 7161 M00694 cGMP signaling 0.999999999991423 -8.57743822823157e-12 9 0 0 28 7161 hsa_M00131 Inositol phosphate metabolism, Ins(1,3,4,5)P4 => Ins(1,3,4)P3 => myo-inositol 0.999999999991423 -8.57743822823157e-12 9 0 0 28 7161 M00361 Nucleotide sugar biosynthesis, eukaryotes 0.999999999991423 -8.57743822823157e-12 9 0 0 28 7161 hsa_M00135 GABA biosynthesis, eukaryotes, putrescine => GABA 0.999999999991423 -8.57743822823157e-12 9 0 0 28 7161 M00131 Inositol phosphate metabolism, Ins(1,3,4,5)P4 => Ins(1,3,4)P3 => myo-inositol 0.999999999991423 -8.57743822823157e-12 9 0 0 28 7161 hsa04064 NF-kappa B signaling pathway 0.999999999991538 -8.46224565849057e-12 94 0 0 28 7161 ko04064 NF-kappa B signaling pathway 0.999999999991538 -8.46224565849057e-12 94 0 0 28 7161 hsa05012 Parkinson's disease 0.999999999991731 -8.2689730058121e-12 129 0 0 28 7161 ko05144 Malaria 0.999999999991984 -8.01652906032857e-12 49 0 0 28 7161 hsa00510 N-Glycan biosynthesis 0.999999999991984 -8.01652906032857e-12 49 0 0 28 7161 hsa05144 Malaria 0.999999999991984 -8.01652906032857e-12 49 0 0 28 7161 hsa00330 Arginine and proline metabolism 0.999999999991984 -8.01652906032857e-12 49 0 0 28 7161 hsa05030 Cocaine addiction 0.999999999991984 -8.01652906032857e-12 49 0 0 28 7161 ko05030 Cocaine addiction 0.999999999991984 -8.01652906032857e-12 49 0 0 28 7161 ko00330 Arginine and proline metabolism 0.999999999991984 -8.01652906032857e-12 49 0 0 28 7161 ko00510 N-Glycan biosynthesis 0.999999999991984 -8.01652906032857e-12 49 0 0 28 7161 hsa04152 AMPK signaling pathway 0.999999999992081 -7.91889013202285e-12 120 0 0 28 7161 hsa00190 Oxidative phosphorylation 0.999999999992081 -7.91889013202285e-12 120 0 0 28 7161 ko00190 Oxidative phosphorylation 0.999999999992081 -7.91889013202285e-12 120 0 0 28 7161 ko04152 AMPK signaling pathway 0.999999999992081 -7.91889013202285e-12 120 0 0 28 7161 hsa00980 Metabolism of xenobiotics by cytochrome P450 0.999999999992353 -7.64710989960951e-12 73 0 0 28 7161 ko00980 Metabolism of xenobiotics by cytochrome P450 0.999999999992353 -7.64710989960951e-12 73 0 0 28 7161 ko00900 Terpenoid backbone biosynthesis 0.999999999992646 -7.35352051273053e-12 22 0 0 28 7161 hsa_M00009 Citrate cycle (TCA cycle, Krebs cycle) 0.999999999992646 -7.35352051273053e-12 22 0 0 28 7161 ko00514 Other types of O-glycan biosynthesis 0.999999999992646 -7.35352051273053e-12 22 0 0 28 7161 M00009 Citrate cycle (TCA cycle, Krebs cycle) 0.999999999992646 -7.35352051273053e-12 22 0 0 28 7161 hsa00514 Other types of O-glycan biosynthesis 0.999999999992646 -7.35352051273053e-12 22 0 0 28 7161 hsa00900 Terpenoid backbone biosynthesis 0.999999999992646 -7.35352051273053e-12 22 0 0 28 7161 hsa_M00177 Ribosome, eukaryotes 0.999999999993173 -6.8266985027092e-12 91 0 0 28 7161 M00177 Ribosome, eukaryotes 0.999999999993173 -6.8266985027092e-12 91 0 0 28 7161 ko00970 Aminoacyl-tRNA biosynthesis 0.999999999993213 -6.78738274555866e-12 44 0 0 28 7161 ko00071 Fatty acid degradation 0.999999999993213 -6.78738274555866e-12 44 0 0 28 7161 hsa00071 Fatty acid degradation 0.999999999993213 -6.78738274555866e-12 44 0 0 28 7161 hsa00970 Aminoacyl-tRNA biosynthesis 0.999999999993213 -6.78738274555866e-12 44 0 0 28 7161 hsa03410 Base excision repair 0.999999999993531 -6.46940365392665e-12 33 0 0 28 7161 ko00051 Fructose and mannose metabolism 0.999999999993531 -6.46940365392665e-12 33 0 0 28 7161 ko03410 Base excision repair 0.999999999993531 -6.46940365392665e-12 33 0 0 28 7161 hsa00051 Fructose and mannose metabolism 0.999999999993531 -6.46940365392665e-12 33 0 0 28 7161 ko00860 Porphyrin and chlorophyll metabolism 0.99999999999369 -6.310445436021e-12 42 0 0 28 7161 hsa00860 Porphyrin and chlorophyll metabolism 0.99999999999369 -6.310445436021e-12 42 0 0 28 7161 ko04146 Peroxisome 0.999999999993993 -6.00724120482695e-12 83 0 0 28 7161 hsa05410 Hypertrophic cardiomyopathy (HCM) 0.999999999993993 -6.00724120482695e-12 83 0 0 28 7161 ko05410 Hypertrophic cardiomyopathy (HCM) 0.999999999993993 -6.00724120482695e-12 83 0 0 28 7161 hsa04146 Peroxisome 0.999999999993993 -6.00724120482695e-12 83 0 0 28 7161 hsa00590 Arachidonic acid metabolism 0.999999999994134 -5.86587777909532e-12 62 0 0 28 7161 ko00590 Arachidonic acid metabolism 0.999999999994134 -5.86587777909532e-12 62 0 0 28 7161 hsa04122 Sulfur relay system 0.999999999994461 -5.5390288814941e-12 8 0 0 28 7161 hsa00740 Riboflavin metabolism 0.999999999994461 -5.5390288814941e-12 8 0 0 28 7161 ko00740 Riboflavin metabolism 0.999999999994461 -5.5390288814941e-12 8 0 0 28 7161 M00428 eIF4F complex 0.999999999994461 -5.5390288814941e-12 8 0 0 28 7161 M00409 ESCRT-I complex 0.999999999994461 -5.5390288814941e-12 8 0 0 28 7161 hsa_M00428 eIF4F complex 0.999999999994461 -5.5390288814941e-12 8 0 0 28 7161 M00065 GPI-anchor biosynthesis, core oligosaccharide 0.999999999994461 -5.5390288814941e-12 8 0 0 28 7161 M00680 TGF-beta signaling 0.999999999994461 -5.5390288814941e-12 8 0 0 28 7161 hsa_M00065 GPI-anchor biosynthesis, core oligosaccharide 0.999999999994461 -5.5390288814941e-12 8 0 0 28 7161 M00687 MAPK (ERK1/2) signaling 0.999999999994461 -5.5390288814941e-12 8 0 0 28 7161 hsa_M00010 Citrate cycle, first carbon oxidation, oxaloacetate => 2-oxoglutarate 0.999999999994461 -5.5390288814941e-12 8 0 0 28 7161 ko04122 Sulfur relay system 0.999999999994461 -5.5390288814941e-12 8 0 0 28 7161 hsa_M00409 ESCRT-I complex 0.999999999994461 -5.5390288814941e-12 8 0 0 28 7161 hsa_M00406 TREX complex 0.999999999994461 -5.5390288814941e-12 8 0 0 28 7161 M00077 Chondroitin sulfate degradation 0.999999999994461 -5.5390288814941e-12 8 0 0 28 7161 hsa_M00680 TGF-beta signaling 0.999999999994461 -5.5390288814941e-12 8 0 0 28 7161 M00406 TREX complex 0.999999999994461 -5.5390288814941e-12 8 0 0 28 7161 M00010 Citrate cycle, first carbon oxidation, oxaloacetate => 2-oxoglutarate 0.999999999994461 -5.5390288814941e-12 8 0 0 28 7161 hsa_M00687 MAPK (ERK1/2) signaling 0.999999999994461 -5.5390288814941e-12 8 0 0 28 7161 hsa_M00077 Chondroitin sulfate degradation 0.999999999994461 -5.5390288814941e-12 8 0 0 28 7161 hsa01200 Carbon metabolism 0.999999999994595 -5.40512565216452e-12 114 0 0 28 7161 ko01200 Carbon metabolism 0.999999999994595 -5.40512565216452e-12 114 0 0 28 7161 ko04742 Taste transduction 0.999999999994596 -5.40367526322117e-12 82 0 0 28 7161 hsa05204 Chemical carcinogenesis 0.999999999994596 -5.40367526322117e-12 82 0 0 28 7161 hsa04742 Taste transduction 0.999999999994596 -5.40367526322117e-12 82 0 0 28 7161 hsa04512 ECM-receptor interaction 0.999999999994596 -5.40367526322117e-12 82 0 0 28 7161 ko05204 Chemical carcinogenesis 0.999999999994596 -5.40367526322117e-12 82 0 0 28 7161 ko04512 ECM-receptor interaction 0.999999999994596 -5.40367526322117e-12 82 0 0 28 7161 hsa00072 Synthesis and degradation of ketone bodies 0.999999999994781 -5.21877437725957e-12 10 0 0 28 7161 hsa_M00681 Activin signaling 0.999999999994781 -5.21877437725957e-12 10 0 0 28 7161 hsa00920 Sulfur metabolism 0.999999999994781 -5.21877437725957e-12 10 0 0 28 7161 M00413 FA core complex 0.999999999994781 -5.21877437725957e-12 10 0 0 28 7161 M00095 C5 isoprenoid biosynthesis, mevalonate pathway 0.999999999994781 -5.21877437725957e-12 10 0 0 28 7161 hsa_M00413 FA core complex 0.999999999994781 -5.21877437725957e-12 10 0 0 28 7161 hsa_M00351 Spliceosome, U1-snRNP 0.999999999994781 -5.21877437725957e-12 10 0 0 28 7161 M00152 Cytochrome bc1 complex 0.999999999994781 -5.21877437725957e-12 10 0 0 28 7161 hsa_M00152 Cytochrome bc1 complex 0.999999999994781 -5.21877437725957e-12 10 0 0 28 7161 hsa_M00296 BER complex 0.999999999994781 -5.21877437725957e-12 10 0 0 28 7161 M00351 Spliceosome, U1-snRNP 0.999999999994781 -5.21877437725957e-12 10 0 0 28 7161 M00426 Survival motor neuron (SMN) complex 0.999999999994781 -5.21877437725957e-12 10 0 0 28 7161 hsa_M00391 Exosome, eukaryotes 0.999999999994781 -5.21877437725957e-12 10 0 0 28 7161 M00059 Glycosaminoglycan biosynthesis, heparan sulfate backbone 0.999999999994781 -5.21877437725957e-12 10 0 0 28 7161 M00681 Activin signaling 0.999999999994781 -5.21877437725957e-12 10 0 0 28 7161 M00296 BER complex 0.999999999994781 -5.21877437725957e-12 10 0 0 28 7161 hsa_M00095 C5 isoprenoid biosynthesis, mevalonate pathway 0.999999999994781 -5.21877437725957e-12 10 0 0 28 7161 M00391 Exosome, eukaryotes 0.999999999994781 -5.21877437725957e-12 10 0 0 28 7161 hsa_M00059 Glycosaminoglycan biosynthesis, heparan sulfate backbone 0.999999999994781 -5.21877437725957e-12 10 0 0 28 7161 ko00920 Sulfur metabolism 0.999999999994781 -5.21877437725957e-12 10 0 0 28 7161 ko00072 Synthesis and degradation of ketone bodies 0.999999999994781 -5.21877437725957e-12 10 0 0 28 7161 M00693 Cell cycle - G2/M transition 0.999999999994781 -5.21877437725957e-12 10 0 0 28 7161 hsa_M00426 Survival motor neuron (SMN) complex 0.999999999994781 -5.21877437725957e-12 10 0 0 28 7161 hsa_M00693 Cell cycle - G2/M transition 0.999999999994781 -5.21877437725957e-12 10 0 0 28 7161 hsa_M00396 Lsm 2-8 complex 0.999999999995192 -4.80821204625645e-12 7 0 0 28 7161 M00072 N-glycosylation by oligosaccharyltransferase 0.999999999995192 -4.80821204625645e-12 7 0 0 28 7161 hsa_M00072 N-glycosylation by oligosaccharyltransferase 0.999999999995192 -4.80821204625645e-12 7 0 0 28 7161 M00398 Sm core complex 0.999999999995192 -4.80821204625645e-12 7 0 0 28 7161 M00396 Lsm 2-8 complex 0.999999999995192 -4.80821204625645e-12 7 0 0 28 7161 M00092 Phosphatidylethanolamine (PE) biosynthesis, ethanolamine => PE 0.999999999995192 -4.80821204625645e-12 7 0 0 28 7161 hsa_M00549 Nucleotide sugar biosynthesis, glucose => UDP-glucose 0.999999999995192 -4.80821204625645e-12 7 0 0 28 7161 M00047 Creatine pathway 0.999999999995192 -4.80821204625645e-12 7 0 0 28 7161 hsa_M00086 beta-Oxidation, acyl-CoA synthesis 0.999999999995192 -4.80821204625645e-12 7 0 0 28 7161 hsa_M00120 Coenzyme A biosynthesis, pantothenate => CoA 0.999999999995192 -4.80821204625645e-12 7 0 0 28 7161 hsa_M00397 Lsm 1-7 complex 0.999999999995192 -4.80821204625645e-12 7 0 0 28 7161 hsa_M00047 Creatine pathway 0.999999999995192 -4.80821204625645e-12 7 0 0 28 7161 hsa_M00007 Pentose phosphate pathway, non-oxidative phase, fructose 6P => ribose 5P 0.999999999995192 -4.80821204625645e-12 7 0 0 28 7161 M00086 beta-Oxidation, acyl-CoA synthesis 0.999999999995192 -4.80821204625645e-12 7 0 0 28 7161 M00120 Coenzyme A biosynthesis, pantothenate => CoA 0.999999999995192 -4.80821204625645e-12 7 0 0 28 7161 M00397 Lsm 1-7 complex 0.999999999995192 -4.80821204625645e-12 7 0 0 28 7161 hsa_M00398 Sm core complex 0.999999999995192 -4.80821204625645e-12 7 0 0 28 7161 hsa_M00691 DNA damage-induced cell cycle checkpoints 0.999999999995192 -4.80821204625645e-12 7 0 0 28 7161 M00007 Pentose phosphate pathway, non-oxidative phase, fructose 6P => ribose 5P 0.999999999995192 -4.80821204625645e-12 7 0 0 28 7161 M00549 Nucleotide sugar biosynthesis, glucose => UDP-glucose 0.999999999995192 -4.80821204625645e-12 7 0 0 28 7161 M00691 DNA damage-induced cell cycle checkpoints 0.999999999995192 -4.80821204625645e-12 7 0 0 28 7161 hsa_M00092 Phosphatidylethanolamine (PE) biosynthesis, ethanolamine => PE 0.999999999995192 -4.80821204625645e-12 7 0 0 28 7161 hsa04640 Hematopoietic cell lineage 0.999999999995343 -4.65669443723731e-12 96 0 0 28 7161 ko04640 Hematopoietic cell lineage 0.999999999995343 -4.65669443723731e-12 96 0 0 28 7161 hsa05033 Nicotine addiction 0.999999999995365 -4.63495330049037e-12 40 0 0 28 7161 ko05033 Nicotine addiction 0.999999999995365 -4.63495330049037e-12 40 0 0 28 7161 hsa00380 Tryptophan metabolism 0.999999999995365 -4.63495330049037e-12 40 0 0 28 7161 ko00380 Tryptophan metabolism 0.999999999995365 -4.63495330049037e-12 40 0 0 28 7161 ko05215 Prostate cancer 0.999999999995546 -4.45371140424901e-12 87 0 0 28 7161 hsa05215 Prostate cancer 0.999999999995546 -4.45371140424901e-12 87 0 0 28 7161 hsa05323 Rheumatoid arthritis 0.999999999995699 -4.30089032941291e-12 89 0 0 28 7161 ko05323 Rheumatoid arthritis 0.999999999995699 -4.30089032941291e-12 89 0 0 28 7161 ko00100 Steroid biosynthesis 0.999999999996235 -3.7650705042911e-12 20 0 0 28 7161 hsa00670 One carbon pool by folate 0.999999999996235 -3.7650705042911e-12 20 0 0 28 7161 ko00532 Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate 0.999999999996235 -3.7650705042911e-12 20 0 0 28 7161 hsa_M00352 Spliceosome, U2-snRNP 0.999999999996235 -3.7650705042911e-12 20 0 0 28 7161 ko00670 One carbon pool by folate 0.999999999996235 -3.7650705042911e-12 20 0 0 28 7161 hsa00532 Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate 0.999999999996235 -3.7650705042911e-12 20 0 0 28 7161 hsa00100 Steroid biosynthesis 0.999999999996235 -3.7650705042911e-12 20 0 0 28 7161 M00352 Spliceosome, U2-snRNP 0.999999999996235 -3.7650705042911e-12 20 0 0 28 7161 ko04115 p53 signaling pathway 0.999999999996238 -3.76214730767696e-12 69 0 0 28 7161 hsa04115 p53 signaling pathway 0.999999999996238 -3.76214730767696e-12 69 0 0 28 7161 ko00982 Drug metabolism - cytochrome P450 0.999999999996238 -3.76214730767696e-12 69 0 0 28 7161 hsa05218 Melanoma 0.999999999996238 -3.76214730767696e-12 69 0 0 28 7161 ko05218 Melanoma 0.999999999996238 -3.76214730767696e-12 69 0 0 28 7161 hsa00982 Drug metabolism - cytochrome P450 0.999999999996238 -3.76214730767696e-12 69 0 0 28 7161 ko01230 Biosynthesis of amino acids 0.999999999996913 -3.08660063337914e-12 74 0 0 28 7161 hsa01230 Biosynthesis of amino acids 0.999999999996913 -3.08660063337914e-12 74 0 0 28 7161 ko04120 Ubiquitin mediated proteolysis 0.999999999997307 -2.6934354705455e-12 137 0 0 28 7161 hsa04120 Ubiquitin mediated proteolysis 0.999999999997307 -2.6934354705455e-12 137 0 0 28 7161 hsa05211 Renal cell carcinoma 0.999999999997495 -2.50542724570946e-12 64 0 0 28 7161 ko05211 Renal cell carcinoma 0.999999999997495 -2.50542724570946e-12 64 0 0 28 7161 hsa_M00104 Bile acid biosynthesis, cholesterol => cholate/chenodeoxycholate 0.999999999997712 -2.28794591119493e-12 12 0 0 28 7161 hsa_M00094 Ceramide biosynthesis 0.999999999997712 -2.28794591119493e-12 12 0 0 28 7161 hsa_M00412 ESCRT-III complex 0.999999999997712 -2.28794591119493e-12 12 0 0 28 7161 M00182 RNA polymerase I, eukaryotes 0.999999999997712 -2.28794591119493e-12 12 0 0 28 7161 M00104 Bile acid biosynthesis, cholesterol => cholate/chenodeoxycholate 0.999999999997712 -2.28794591119493e-12 12 0 0 28 7161 M00290 Holo-TFIIH complex 0.999999999997712 -2.28794591119493e-12 12 0 0 28 7161 hsa_M00002 Glycolysis, core module involving three-carbon compounds 0.999999999997712 -2.28794591119493e-12 12 0 0 28 7161 M00087 beta-Oxidation 0.999999999997712 -2.28794591119493e-12 12 0 0 28 7161 hsa_M00388 ECS complex 0.999999999997712 -2.28794591119493e-12 12 0 0 28 7161 M00002 Glycolysis, core module involving three-carbon compounds 0.999999999997712 -2.28794591119493e-12 12 0 0 28 7161 M00412 ESCRT-III complex 0.999999999997712 -2.28794591119493e-12 12 0 0 28 7161 hsa_M00004 Pentose phosphate pathway (Pentose phosphate cycle) 0.999999999997712 -2.28794591119493e-12 12 0 0 28 7161 M00052 Pyrimidine ribonucleotide biosynthesis, UMP => UDP/UTP,CDP/CTP 0.999999999997712 -2.28794591119493e-12 12 0 0 28 7161 M00094 Ceramide biosynthesis 0.999999999997712 -2.28794591119493e-12 12 0 0 28 7161 M00004 Pentose phosphate pathway (Pentose phosphate cycle) 0.999999999997712 -2.28794591119493e-12 12 0 0 28 7161 hsa_M00182 RNA polymerase I, eukaryotes 0.999999999997712 -2.28794591119493e-12 12 0 0 28 7161 M00388 ECS complex 0.999999999997712 -2.28794591119493e-12 12 0 0 28 7161 hsa_M00052 Pyrimidine ribonucleotide biosynthesis, UMP => UDP/UTP,CDP/CTP 0.999999999997712 -2.28794591119493e-12 12 0 0 28 7161 hsa_M00290 Holo-TFIIH complex 0.999999999997712 -2.28794591119493e-12 12 0 0 28 7161 hsa_M00087 beta-Oxidation 0.999999999997712 -2.28794591119493e-12 12 0 0 28 7161 ko04950 Maturity onset diabetes of the young 0.999999999997973 -2.02737846206056e-12 26 0 0 28 7161 hsa04950 Maturity onset diabetes of the young 0.999999999997973 -2.02737846206056e-12 26 0 0 28 7161 hsa03013 RNA transport 0.999999999998161 -1.83943866557143e-12 166 0 0 28 7161 ko03013 RNA transport 0.999999999998161 -1.83943866557143e-12 166 0 0 28 7161 hsa05220 Chronic myeloid leukemia 0.999999999998878 -1.1223981606536e-12 71 0 0 28 7161 ko05220 Chronic myeloid leukemia 0.999999999998878 -1.1223981606536e-12 71 0 0 28 7161 hsa03010 Ribosome 0.999999999998939 -1.06139151215712e-12 134 0 0 28 7161 ko03010 Ribosome 0.999999999998939 -1.06139151215712e-12 134 0 0 28 7161 M00101 Cholesterol biosynthesis, squalene 2,3-epoxide => cholesterol 0.999999999999014 -9.86232185241325e-13 11 0 0 28 7161 M00678 Hedgehog signaling 0.999999999999014 -9.86232185241325e-13 11 0 0 28 7161 hsa_M00032 Lysine degradation, lysine => saccharopine => acetoacetyl-CoA 0.999999999999014 -9.86232185241325e-13 11 0 0 28 7161 hsa_M00098 Acylglycerol degradation 0.999999999999014 -9.86232185241325e-13 11 0 0 28 7161 ko00130 Ubiquinone and other terpenoid-quinone biosynthesis 0.999999999999014 -9.86232185241325e-13 11 0 0 28 7161 hsa_M00404 COPII complex 0.999999999999014 -9.86232185241325e-13 11 0 0 28 7161 hsa00430 Taurine and hypotaurine metabolism 0.999999999999014 -9.86232185241325e-13 11 0 0 28 7161 M00098 Acylglycerol degradation 0.999999999999014 -9.86232185241325e-13 11 0 0 28 7161 M00404 COPII complex 0.999999999999014 -9.86232185241325e-13 11 0 0 28 7161 M00034 Methionine salvage pathway 0.999999999999014 -9.86232185241325e-13 11 0 0 28 7161 hsa00130 Ubiquinone and other terpenoid-quinone biosynthesis 0.999999999999014 -9.86232185241325e-13 11 0 0 28 7161 M00032 Lysine degradation, lysine => saccharopine => acetoacetyl-CoA 0.999999999999014 -9.86232185241325e-13 11 0 0 28 7161 ko00430 Taurine and hypotaurine metabolism 0.999999999999014 -9.86232185241325e-13 11 0 0 28 7161 M00143 NADH dehydrogenase (ubiquinone) Fe-S protein/flavoprotein complex, mitochondria 0.999999999999014 -9.86232185241325e-13 11 0 0 28 7161 hsa_M00034 Methionine salvage pathway 0.999999999999014 -9.86232185241325e-13 11 0 0 28 7161 hsa_M00678 Hedgehog signaling 0.999999999999014 -9.86232185241325e-13 11 0 0 28 7161 hsa_M00143 NADH dehydrogenase (ubiquinone) Fe-S protein/flavoprotein complex, mitochondria 0.999999999999014 -9.86232185241325e-13 11 0 0 28 7161 hsa_M00101 Cholesterol biosynthesis, squalene 2,3-epoxide => cholesterol 0.999999999999014 -9.86232185241325e-13 11 0 0 28 7161 hsa04630 Jak-STAT signaling pathway 1.00000000000039 3.86489073142942e-13 156 0 0 28 7161 ko04630 Jak-STAT signaling pathway 1.00000000000039 3.86489073142942e-13 156 0 0 28 7161 hsa03008 Ribosome biogenesis in eukaryotes 1.0000000000004 4.01295171401776e-13 79 0 0 28 7161 ko03008 Ribosome biogenesis in eukaryotes 1.0000000000004 4.01295171401776e-13 79 0 0 28 7161 hsa_M00284 Origin recognition complex 1.00000000000045 4.47444218368524e-13 6 0 0 28 7161 hsa_M00395 Decapping complex 1.00000000000045 4.47444218368524e-13 6 0 0 28 7161 hsa_M00090 Phosphatidylcholine (PC) biosynthesis, choline => PC 1.00000000000045 4.47444218368524e-13 6 0 0 28 7161 hsa_M00073 N-glycan precursor trimming 1.00000000000045 4.47444218368524e-13 6 0 0 28 7161 hsa_M00058 Glycosaminoglycan biosynthesis, chondroitin sulfate backbone 1.00000000000045 4.47444218368524e-13 6 0 0 28 7161 M00285 MCM complex 1.00000000000045 4.47444218368524e-13 6 0 0 28 7161 M00029 Urea cycle 1.00000000000045 4.47444218368524e-13 6 0 0 28 7161 hsa00750 Vitamin B6 metabolism 1.00000000000045 4.47444218368524e-13 6 0 0 28 7161 M00395 Decapping complex 1.00000000000045 4.47444218368524e-13 6 0 0 28 7161 M00109 C21-Steroid hormone biosynthesis, progesterone => cortisol/cortisone 1.00000000000045 4.47444218368524e-13 6 0 0 28 7161 hsa_M00085 Fatty acid biosynthesis, elongation, mitochondria 1.00000000000045 4.47444218368524e-13 6 0 0 28 7161 hsa00440 Phosphonate and phosphinate metabolism 1.00000000000045 4.47444218368524e-13 6 0 0 28 7161 hsa_M00029 Urea cycle 1.00000000000045 4.47444218368524e-13 6 0 0 28 7161 hsa_M00424 Shelterin complex 1.00000000000045 4.47444218368524e-13 6 0 0 28 7161 hsa_M00285 MCM complex 1.00000000000045 4.47444218368524e-13 6 0 0 28 7161 hsa_M00013 Malonate semialdehyde pathway, propanoyl-CoA => acetyl-CoA 1.00000000000045 4.47444218368524e-13 6 0 0 28 7161 ko00750 Vitamin B6 metabolism 1.00000000000045 4.47444218368524e-13 6 0 0 28 7161 M00284 Origin recognition complex 1.00000000000045 4.47444218368524e-13 6 0 0 28 7161 hsa_M00109 C21-Steroid hormone biosynthesis, progesterone => cortisol/cortisone 1.00000000000045 4.47444218368524e-13 6 0 0 28 7161 M00141 C1-unit interconversion, eukaryotes 1.00000000000045 4.47444218368524e-13 6 0 0 28 7161 hsa_M00048 Inosine monophosphate biosynthesis, PRPP + glutamine => IMP 1.00000000000045 4.47444218368524e-13 6 0 0 28 7161 M00073 N-glycan precursor trimming 1.00000000000045 4.47444218368524e-13 6 0 0 28 7161 M00058 Glycosaminoglycan biosynthesis, chondroitin sulfate backbone 1.00000000000045 4.47444218368524e-13 6 0 0 28 7161 M00085 Fatty acid biosynthesis, elongation, mitochondria 1.00000000000045 4.47444218368524e-13 6 0 0 28 7161 M00090 Phosphatidylcholine (PC) biosynthesis, choline => PC 1.00000000000045 4.47444218368524e-13 6 0 0 28 7161 M00424 Shelterin complex 1.00000000000045 4.47444218368524e-13 6 0 0 28 7161 ko00440 Phosphonate and phosphinate metabolism 1.00000000000045 4.47444218368524e-13 6 0 0 28 7161 hsa_M00141 C1-unit interconversion, eukaryotes 1.00000000000045 4.47444218368524e-13 6 0 0 28 7161 M00013 Malonate semialdehyde pathway, propanoyl-CoA => acetyl-CoA 1.00000000000045 4.47444218368524e-13 6 0 0 28 7161 M00048 Inosine monophosphate biosynthesis, PRPP + glutamine => IMP 1.00000000000045 4.47444218368524e-13 6 0 0 28 7161 hsa03018 RNA degradation 1.00000000000326 3.25830302369553e-12 77 0 0 28 7161 hsa04612 Antigen processing and presentation 1.00000000000326 3.25830302369553e-12 77 0 0 28 7161 ko04612 Antigen processing and presentation 1.00000000000326 3.25830302369553e-12 77 0 0 28 7161 ko03018 RNA degradation 1.00000000000326 3.25830302369553e-12 77 0 0 28 7161 ko00053 Ascorbate and aldarate metabolism 1.00000000000333 3.33140244010695e-12 27 0 0 28 7161 ko00601 Glycosphingolipid biosynthesis - lacto and neolacto series 1.00000000000333 3.33140244010695e-12 27 0 0 28 7161 hsa_M00014 Glucuronate pathway (uronate pathway) 1.00000000000333 3.33140244010695e-12 27 0 0 28 7161 hsa_M00056 O-glycan biosynthesis, mucin type core 1.00000000000333 3.33140244010695e-12 27 0 0 28 7161 ko04966 Collecting duct acid secretion 1.00000000000333 3.33140244010695e-12 27 0 0 28 7161 M00014 Glucuronate pathway (uronate pathway) 1.00000000000333 3.33140244010695e-12 27 0 0 28 7161 hsa00601 Glycosphingolipid biosynthesis - lacto and neolacto series 1.00000000000333 3.33140244010695e-12 27 0 0 28 7161 hsa04966 Collecting duct acid secretion 1.00000000000333 3.33140244010695e-12 27 0 0 28 7161 hsa00053 Ascorbate and aldarate metabolism 1.00000000000333 3.33140244010695e-12 27 0 0 28 7161 M00056 O-glycan biosynthesis, mucin type core 1.00000000000333 3.33140244010695e-12 27 0 0 28 7161 hsa04740 Olfactory transduction 1.00000000000639 6.39095528529073e-12 415 0 0 28 7161 ko04740 Olfactory transduction 1.00000000000639 6.39095528529073e-12 415 0 0 28 7161 hsa00140 Steroid hormone biosynthesis 1.00000000000663 6.62847291605324e-12 58 0 0 28 7161 ko00140 Steroid hormone biosynthesis 1.00000000000663 6.62847291605324e-12 58 0 0 28 7161 ko04145 Phagosome 1.00000000000922 9.22343645966388e-12 152 0 0 28 7161 hsa04145 Phagosome 1.00000000000922 9.22343645966388e-12 152 0 0 28 7161