Gene Ontology Enrichment Results

Homer de novo Motif Enrichment Results
Known Motif Enrichment Results

Text file version of complete results (i.e. open with Excel)

biological process: Functional groupings of proteins (Gene Ontology)

molecular function: Mechanistic actions of proteins (Gene Ontology)

cellular component: Protein localization (Gene Ontology)

chromosome location: Genes with similar chromosome localization (NCBI Gene)

KEGG pathways: Groups of proteins in the same pathways (KEGG)

protein interactions: "Proteins interacting with a common protein (BIND, EcoCyc, HPRD)" (NCBI Gene)

interpro domains: Proteins with similar domains and features (Interpro)

pfam domains: Proteins with similar domains and features (Pfam)

smart domains: Proteins with similar domains and features (SMART)

gene3d domains: Proteins with similar domains and features (Gene3D)

prosite domains: Proteins with similar domains and features (Prosite)

prints domains: Proteins with similar domains and features (PRINTS)

MSigDB lists: "Genes sets for pathways, factor/miRNA target predictions, expression patterns, etc." (MSigDB)

BIOCYC pathways: Groups of proteins in the same pathways (BIOCYC)

COSMIC cancer mutations: Genes mutated in similar cancers (COSMIC)

GWAS genes: Genes mutated in similar diseases (GWAS Catalog)

Lipid Maps pathways: Groups of proteins in the same lipid pathways (Lipid Maps/Biosystems)

Pathway Interaction DB: Groups of proteins in the same pathways (Pathway Interaction Database)

REACTOME pathways: Groups of proteins in the same pathways (REACTOME)

SMPDB pathways: Groups of proteins in the same pathways (SMPDB)

WikiPathways: Groups of proteins in the same pathways (Wikipathways)

Enriched Categories

P-value	ln(P)	Term	GO Tree	GO ID	# of Genes in Term	# of Target Genes in Term	# of Total Genes	# of Target Genes	Common Genes
1.647e-09	-20.22	brainstem	COSMIC cancer mutations	brainstem	3102	28	16828	49	SOX5,ATP13A4,RYR3,TPD52L1,RORA,FBXL7,GPM6A,CADM1,ZBTB20,PREX2,MAML2,PARD3,NKAIN3,FGFR3,GPC5,NPAS3,SLC1A3,QKI,ZNRF3,ERBB4,HPSE2,AHCYL2,CTNND2,LSAMP,SASH1,SLC1A2,CDH20,TNIK
3.796e-09	-19.39	central_nervous_system-brainstem-glioma-astrocytoma_Grade_IV	COSMIC cancer mutations	central_nervous_system-brainstem-glioma-astrocytoma_Grade_IV	2531	25	16828	49	RORA,GPM6A,FBXL7,MAML2,PREX2,CADM1,ZBTB20,ATP13A4,SOX5,RYR3,TPD52L1,GPC5,SLC1A3,PARD3,NKAIN3,CTNND2,LSAMP,SASH1,ZNRF3,QKI,ERBB4,HPSE2,AHCYL2,CDH20,TNIK
3.883e-09	-19.37	Burkitt_lymphoma	COSMIC cancer mutations	Burkitt_lymphoma	2119	23	16828	49	NPAS3,GPC5,SLC1A3,NHSL1,NKAIN3,PARD3,FBXL7,GPM6A,CADM1,PREX2,MAML2,SOX5,ATP13A4,RYR3,TPD52L1,DOCK4,SLC1A2,SASH1,CTNND2,LSAMP,HPSE2,AHCYL2,ERBB4
3.883e-09	-19.37	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-Burkitt_lymphoma	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-Burkitt_lymphoma	2119	23	16828	49	AHCYL2,HPSE2,TPD52L1,ERBB4,ATP13A4,SOX5,RYR3,CADM1,PREX2,MAML2,SASH1,GPM6A,FBXL7,LSAMP,CTNND2,NKAIN3,DOCK4,SLC1A2,PARD3,NHSL1,SLC1A3,GPC5,NPAS3
9.808e-09	-18.44	PRNP (prion protein (Kanno blood group))	protein interactions	5621	1118	16	19454	50	NHSL1,DOCK4,MAML2,SLC4A4,QKI,TRPS1,ATP1A2,CLU,LSAMP,GPM6A,TRPM3,MSI2,ABLIM1,CAMK2G,AHCYL2,SLC1A3
1.500e-08	-18.01	myelodysplastic_syndrome	COSMIC cancer mutations	myelodysplastic_syndrome	1174	17	16828	49	LSAMP,PREX2,FBXL7,CAMK2G,ERBB4,RYR3,SOX5,ATP1A2,HPSE2,FGFR3,COL5A3,NPAS3,NFIA,SLC1A2,PARD3,NKAIN3,TNIK
1.500e-08	-18.01	haematopoietic_and_lymphoid_tissue-haematopoietic_neoplasm-myelodysplastic_syndrome	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue-haematopoietic_neoplasm-myelodysplastic_syndrome	1174	17	16828	49	NKAIN3,TNIK,PARD3,SLC1A2,NFIA,NPAS3,COL5A3,FGFR3,HPSE2,ATP1A2,RYR3,SOX5,ERBB4,CAMK2G,FBXL7,PREX2,LSAMP
2.157e-08	-17.65	haematopoietic_and_lymphoid_tissue-haematopoietic_neoplasm	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue-haematopoietic_neoplasm	764	14	16828	49	NKAIN3,SLC1A2,PARD3,GPC5,COL5A3,ATP1A2,HPSE2,ERBB4,SOX5,RYR3,MAML2,PREX2,FBXL7,LSAMP
8.769e-08	-16.25	nervous system development	biological process	GO:0007399	2185	21	18204	50	QKI,ATP1A2,SLC1A3,CAMK2G,CTNNA2,LSAMP,CTNND2,NDRG2,RORA,NTM,MSI2,PARD3,DAAM2,PREX2,ERBB4,CLU,TNIK,SLC1A2,SOX5,NFIA,GPM6A
1.317e-07	-15.84	Astrocytic Glutamate-Glutamine Uptake And Metabolism	REACTOME pathways	R-HSA-210455	4	3	10285	34	SLC1A2,SLC1A3,GLUL
1.317e-07	-15.84	Neurotransmitter uptake and Metabolism In Glial Cells	REACTOME pathways	R-HSA-112313	4	3	10285	34	SLC1A2,SLC1A3,GLUL
2.559e-07	-15.18	upper_aerodigestive_tract-mouth-carcinoma-squamous_cell_carcinoma	COSMIC cancer mutations	upper_aerodigestive_tract-mouth-carcinoma-squamous_cell_carcinoma	6953	38	16828	49	RORA,FBXL7,CAMK2G,GPM6A,CADM1,ZBTB20,PREX2,MAML2,ATP13A4,SOX5,RYR3,NTM,ATP1A2,FGFR3,GPC5,NHSL1,NDRG2,PARD3,PITPNC1,TRPM3,DTNA,CTNND2,ABLIM1,LSAMP,SASH1,SLC25A18,DAAM2,QKI,ZNRF3,ERBB4,CST3,TRPS1,SLC4A4,SLC1A2,CDH20,GLUL,TNIK,DOCK4
2.732e-07	-15.11	blood_vessel	COSMIC cancer mutations	blood_vessel	2211	21	16828	49	CTNND2,LSAMP,GPM6A,FBXL7,SASH1,MAML2,PREX2,CADM1,RYR3,SOX5,TPD52L1,ERBB4,HPSE2,COL5A3,FGFR3,GPC5,SLC1A3,PARD3,SLC1A2,CDH20,NKAIN3
2.803e-07	-15.09	diffuse_large_B_cell_lymphoma	COSMIC cancer mutations	diffuse_large_B_cell_lymphoma	4151	29	16828	49	CADM1,PREX2,MAML2,FBXL7,GPM6A,RORA,ATP1A2,TPD52L1,RYR3,ATP13A4,SOX5,SLC1A3,GPC5,FGFR3,NKAIN3,DTNA,PARD3,SASH1,LSAMP,CTNND2,AHCYL2,HPSE2,TRPS1,ERBB4,QKI,TNIK,CDH20,CLU,SLC1A2
3.377e-07	-14.90	mouth	COSMIC cancer mutations	mouth	9004	43	16828	49	SASH1,DAAM2,SLC25A18,QKI,ERBB4,HPSE2,CLU,CDH20,DOCK4,FBXL7,GPM6A,PREX2,MAML2,ATP13A4,SOX5,ATP1A2,COL5A3,GPC5,PITPNC1,TRPM3,CTNND2,LSAMP,ABLIM1,ZNRF3,CST3,TRPS1,SLC4A4,SLC1A2,GLUL,TNIK,RORA,CAMK2G,CADM1,ZBTB20,RYR3,NTM,FGFR3,NPAS3,NHSL1,SLC1A3,NDRG2,PARD3,DTNA
6.051e-07	-14.32	multicellular organism development	biological process	GO:0007275	3957	27	18204	50	NFIA,GPM6A,SLC1A2,SOX5,CADM1,PREX2,MSI2,CAMK2G,CTNND2,NDRG2,GLUL,ATP1A2,SLC1A3,TRPS1,ZNRF3,CDH20,TNIK,ERBB4,CLU,NTM,RORA,PARD3,DAAM2,CTNNA2,LSAMP,QKI,FGFR3
6.069e-07	-14.31	lymph_node	COSMIC cancer mutations	lymph_node	1703	18	16828	49	GPC5,SLC1A3,FGFR3,TRPM3,TNIK,DTNA,PARD3,GPM6A,CAMK2G,CADM1,MAML2,CTNND2,LSAMP,TRPS1,RYR3,SOX5,ATP13A4,ERBB4
6.567e-07	-14.24	acute_myeloid_leukaemia_therapy_related	COSMIC cancer mutations	acute_myeloid_leukaemia_therapy_related	1523	17	16828	49	NKAIN3,PARD3,SLC1A3,GPC5,COL5A3,HPSE2,ERBB4,RYR3,SOX5,QKI,CADM1,MAML2,PREX2,FBXL7,LSAMP,RORA,CTNND2
6.567e-07	-14.24	haematopoietic_and_lymphoid_tissue-haematopoietic_neoplasm-acute_myeloid_leukaemia_therapy_related	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue-haematopoietic_neoplasm-acute_myeloid_leukaemia_therapy_related	1523	17	16828	49	SOX5,QKI,RYR3,ERBB4,HPSE2,CTNND2,LSAMP,RORA,FBXL7,CADM1,PREX2,MAML2,PARD3,NKAIN3,COL5A3,GPC5,SLC1A3
9.113e-07	-13.91	haematopoietic_and_lymphoid_tissue-lymph_node-lymphoid_neoplasm-mantle_cell_lymphoma	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue-lymph_node-lymphoid_neoplasm-mantle_cell_lymphoma	476	10	16828	49	LSAMP,CTNND2,CADM1,MAML2,GPM6A,GPC5,ERBB4,RYR3,ATP13A4,TRPM3
1.129e-06	-13.69	system development	biological process	GO:0048731	3533	25	18204	50	CAMK2G,CTNND2,NDRG2,GLUL,ATP1A2,SLC1A3,PREX2,MSI2,SLC1A2,SOX5,CADM1,NFIA,GPM6A,CTNNA2,LSAMP,QKI,FGFR3,RORA,NTM,PARD3,DAAM2,TNIK,CLU,ERBB4,TRPS1
1.153e-06	-13.67	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-diffuse_large_B_cell_lymphoma	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-diffuse_large_B_cell_lymphoma	3608	26	16828	49	LSAMP,CTNND2,SASH1,ERBB4,QKI,AHCYL2,HPSE2,SLC1A2,CLU,TNIK,CDH20,RORA,MAML2,PREX2,CADM1,GPM6A,FBXL7,TPD52L1,RYR3,SOX5,ATP13A4,ATP1A2,FGFR3,GPC5,PARD3,NKAIN3
1.170e-06	-13.66	soft_tissue-blood_vessel-angiosarcoma	COSMIC cancer mutations	soft_tissue-blood_vessel-angiosarcoma	2192	20	16828	49	SOX5,RYR3,ERBB4,TPD52L1,HPSE2,CTNND2,LSAMP,SASH1,GPM6A,FBXL7,CADM1,PREX2,MAML2,PARD3,SLC1A2,CDH20,NKAIN3,COL5A3,GPC5,SLC1A3
1.170e-06	-13.66	angiosarcoma	COSMIC cancer mutations	angiosarcoma	2192	20	16828	49	COL5A3,SLC1A3,GPC5,SLC1A2,PARD3,NKAIN3,CDH20,LSAMP,CTNND2,PREX2,MAML2,CADM1,FBXL7,GPM6A,SASH1,ERBB4,TPD52L1,RYR3,SOX5,HPSE2
1.845e-06	-13.20	prostate-carcinoma	COSMIC cancer mutations	prostate-carcinoma	9000	42	16828	49	SLC1A2,CLU,SLC4A4,TNIK,CDH20,ABLIM1,LSAMP,CTNND2,SLC25A18,DAAM2,SASH1,ERBB4,ZNRF3,QKI,AHCYL2,TRPS1,HPSE2,FGFR3,COL5A3,NHSL1,SLC1A3,NPAS3,GPC5,NFIA,PITPNC1,PARD3,DTNA,NKAIN3,TRPM3,RORA,MAML2,PREX2,CADM1,ZBTB20,GPM6A,FBXL7,TPD52L1,NTM,ATP13A4,SOX5,RYR3,MSI2
3.168e-06	-12.66	L-aspartate transmembrane transport	biological process	GO:0070778	11	3	18204	50	SLC1A2,SLC25A18,SLC1A3
3.322e-06	-12.61	central_nervous_system-brain-primitive_neuroectodermal_tumour-medulloblastoma	COSMIC cancer mutations	central_nervous_system-brain-primitive_neuroectodermal_tumour-medulloblastoma	7205	37	16828	49	SLC1A2,SLC4A4,DOCK4,TNIK,LSAMP,ABLIM1,CTNND2,DAAM2,SASH1,ERBB4,QKI,AHCYL2,HPSE2,TRPS1,FGFR3,COL5A3,SLC1A3,NHSL1,NPAS3,GPC5,NFIA,PITPNC1,PARD3,NKAIN3,TRPM3,RORA,PREX2,MAML2,CADM1,ZBTB20,FBXL7,GPM6A,TPD52L1,NTM,SOX5,RYR3,ATP13A4
3.587e-06	-12.54	multicellular organismal process	biological process	GO:0032501	6177	33	18204	50	CAMK2G,NDRG2,CTNND2,DTNA,GLUL,SLC1A3,ATP1A2,SLC4A4,PREX2,ABLIM1,MSI2,SLC1A2,SOX5,PTGDS,CADM1,RYR3,NFIA,GPM6A,CTNNA2,LSAMP,QKI,FGFR3,NTM,RORA,DAAM2,PARD3,TNIK,CLU,ERBB4,DOCK4,ZNRF3,TRPS1,CDH20
3.650e-06	-12.52	MAPT (microtubule associated protein tau)	protein interactions	4137	948	12	19454	50	TNIK,GPM6A,LSAMP,CLU,SLC1A3,CTNNA2,ABLIM1,NDRG2,SLC1A2,NTM,CTNND2,ATP1A2
3.755e-06	-12.49	acute_lymphoblastic_B_cell_leukaemia	COSMIC cancer mutations	acute_lymphoblastic_B_cell_leukaemia	3828	26	16828	49	TNIK,SLC4A4,SLC1A2,HPSE2,ERBB4,SASH1,DAAM2,CTNND2,LSAMP,NKAIN3,PARD3,NFIA,GPC5,SLC1A3,COL5A3,SOX5,ATP13A4,RYR3,NTM,GPM6A,FBXL7,CADM1,ZBTB20,MAML2,PREX2,RORA
3.755e-06	-12.49	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-acute_lymphoblastic_B_cell_leukaemia	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-acute_lymphoblastic_B_cell_leukaemia	3828	26	16828	49	GPM6A,FBXL7,MAML2,PREX2,ZBTB20,CADM1,RORA,ATP13A4,SOX5,RYR3,NTM,GPC5,SLC1A3,COL5A3,NKAIN3,PARD3,NFIA,DAAM2,SASH1,CTNND2,LSAMP,HPSE2,ERBB4,TNIK,SLC4A4,SLC1A2
3.952e-06	-12.44	neuron projection	cellular component	GO:0043005	1331	14	19108	49	SLC1A2,CTNNA2,CLU,AHCYL2,ATP1A2,SLC1A3,DTNA,DOCK4,CTNND2,GPM6A,CADM1,CAMK2G,PARD3,NDRG2
4.477e-06	-12.32	mantle_cell_lymphoma	COSMIC cancer mutations	mantle_cell_lymphoma	2849	22	16828	49	CADM1,PREX2,MAML2,SASH1,DAAM2,GPM6A,FBXL7,LSAMP,CTNND2,HPSE2,TRPS1,ERBB4,ATP13A4,SOX5,RYR3,ZNRF3,SLC1A3,GPC5,NKAIN3,TRPM3,SLC1A2,PARD3
6.248e-06	-11.98	L-glutamate transmembrane transporter activity	molecular function	GO:0005313	14	3	18094	48	SLC1A2,SLC1A3,SLC25A18
9.205e-06	-11.60	neurogenesis	biological process	GO:0022008	1334	14	18204	50	TNIK,ERBB4,CLU,SOX5,NFIA,GPM6A,QKI,SLC1A3,CTNNA2,CTNND2,RORA,NTM,PARD3,PREX2
1.002e-05	-11.51	cerebellum	COSMIC cancer mutations	cerebellum	769	11	16828	49	QKI,RYR3,PARD3,ERBB4,HPSE2,CTNND2,ABLIM1,GPC5,NPAS3,CADM1,MAML2
1.229e-05	-11.31	TIAM1 (TIAM Rac1 associated GEF 1)	protein interactions	7074	201	6	19454	50	CAMK2G,DTNA,ATP1A2,RYR3,DAAM2,PARD3
1.311e-05	-11.24	anatomical structure development	biological process	GO:0048856	5207	29	18204	50	PREX2,MSI2,ABLIM1,CAMK2G,CTNND2,NDRG2,GLUL,ATP1A2,SLC1A3,NFIA,GPM6A,SLC1A2,SOX5,CADM1,RORA,NTM,PARD3,DAAM2,CTNNA2,LSAMP,QKI,FGFR3,TRPS1,ZNRF3,CDH20,TNIK,ERBB4,CLU,COL5A3
1.390e-05	-11.18	acidic amino acid transmembrane transporter activity	molecular function	GO:0015172	18	3	18094	48	SLC25A18,SLC1A2,SLC1A3
1.437e-05	-11.15	cell morphogenesis	biological process	GO:0000902	687	10	18204	50	PREX2,GPM6A,NFIA,CDH20,PARD3,CTNND2,CTNNA2,SLC1A3,TNIK,CLU
1.836e-05	-10.91	CTNNA1 (catenin alpha 1)	protein interactions	1495	325	7	19454	50	NHSL1,PARD3,TNIK,DTNA,ABLIM1,SASH1,CTNNA2
1.881e-05	-10.88	upper_aerodigestive_tract-larynx-carcinoma-squamous_cell_carcinoma	COSMIC cancer mutations	upper_aerodigestive_tract-larynx-carcinoma-squamous_cell_carcinoma	1946	17	16828	49	DOCK4,TNIK,SLC4A4,NPAS3,COL5A3,FGFR3,HPSE2,AHCYL2,ZNRF3,SOX5,RYR3,ERBB4,GPM6A,DAAM2,MAML2,ZBTB20,RORA
1.907e-05	-10.87	larynx	COSMIC cancer mutations	larynx	1948	17	16828	49	TNIK,DOCK4,SLC4A4,NPAS3,FGFR3,COL5A3,AHCYL2,HPSE2,ERBB4,RYR3,SOX5,ZNRF3,ZBTB20,MAML2,GPM6A,DAAM2,RORA
2.020e-05	-10.81	chondroblastoma	COSMIC cancer mutations	chondroblastoma	534	9	16828	49	LSAMP,CTNND2,GPC5,GPM6A,TPD52L1,SOX5,RYR3,AHCYL2,NKAIN3
2.151e-05	-10.75	aspartate transmembrane transport	biological process	GO:0015810	20	3	18204	50	SLC1A2,SLC25A18,SLC1A3
2.188e-05	-10.73	tibia	COSMIC cancer mutations	tibia	836	11	16828	49	TRPM3,TNIK,NKAIN3,QKI,GPM6A,NDRG2,PREX2,CTNND2,FGFR3,LSAMP,ABLIM1
2.312e-05	-10.67	cell population proliferation	biological process	GO:0008283	726	10	18204	50	NFIA,HPSE2,RORA,ZNRF3,NDRG2,SOX5,CADM1,GLUL,CLU,FGFR3
2.428e-05	-10.63	Transport of inorganic cations/anions and amino acids/oligopeptides	REACTOME pathways	R-HSA-425393	107	5	10285	34	SLC1A3,SLC25A18,SLC1A2,SLC4A4,AHCYL2
2.773e-05	-10.49	developmental process	biological process	GO:0032502	5716	30	18204	50	TNIK,CLU,ERBB4,COL5A3,TRPS1,ZNRF3,CDH20,QKI,FGFR3,CTNNA2,LSAMP,NTM,RORA,PARD3,DAAM2,NHSL1,CADM1,SLC1A2,SOX5,NFIA,GPM6A,GLUL,ATP1A2,SLC1A3,CAMK2G,CTNND2,NDRG2,MSI2,ABLIM1,PREX2
2.908e-05	-10.45	bone	COSMIC cancer mutations	bone	8157	38	16828	49	GPM6A,CAMK2G,PREX2,MAML2,ZBTB20,CADM1,RORA,ATP1A2,RYR3,SOX5,ATP13A4,TPD52L1,GPC5,NPAS3,NDRG2,SLC1A3,COL5A3,FGFR3,TRPM3,DTNA,NKAIN3,PARD3,DAAM2,SASH1,CTNND2,LSAMP,ABLIM1,TRPS1,HPSE2,CST3,AHCYL2,QKI,ERBB4,GLUL,PTGDS,DOCK4,TNIK,SLC4A4
3.292e-05	-10.32	upper_aerodigestive_tract-mouth-carcinoma	COSMIC cancer mutations	upper_aerodigestive_tract-mouth-carcinoma	6426	33	16828	49	TRPM3,PITPNC1,PARD3,SLC1A3,NDRG2,NHSL1,NPAS3,GPC5,FGFR3,COL5A3,NTM,SOX5,RYR3,ZBTB20,MAML2,PREX2,FBXL7,GPM6A,RORA,DOCK4,CDH20,CLU,SLC1A2,SLC4A4,TRPS1,HPSE2,ERBB4,QKI,SASH1,SLC25A18,DAAM2,ABLIM1,CTNND2
3.532e-05	-10.25	monoatomic cation transmembrane transporter activity	molecular function	GO:0008324	630	9	18094	48	TRPM3,ATP13A4,RYR3,SLC4A4,SLC25A18,SLC1A2,SLC1A3,ATP1A2,GPM6A
3.622e-05	-10.23	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-mantle_cell_lymphoma	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-mantle_cell_lymphoma	2737	20	16828	49	TRPS1,HPSE2,ERBB4,ZNRF3,SOX5,RYR3,PREX2,MAML2,CADM1,DAAM2,GPM6A,FBXL7,SASH1,LSAMP,CTNND2,NKAIN3,SLC1A2,PARD3,SLC1A3,GPC5
3.982e-05	-10.13	soft_tissue	COSMIC cancer mutations	soft_tissue	5828	31	16828	49	TPD52L1,RYR3,SOX5,MAML2,PREX2,CADM1,CAMK2G,FBXL7,GPM6A,RORA,NKAIN3,TRPM3,NFIA,PARD3,SLC1A3,NHSL1,GPC5,NPAS3,FGFR3,COL5A3,TRPS1,HPSE2,ERBB4,ZNRF3,SASH1,LSAMP,CTNND2,DOCK4,CDH20,SLC1A2,CLU
4.297e-05	-10.05	L-glutamate transmembrane transport	biological process	GO:0015813	25	3	18204	50	SLC1A3,SLC25A18,SLC1A2
4.405e-05	-10.03	Transmembrane transport of small molecules	REACTOME pathways	R-HSA-382551	677	10	10285	34	SLC1A2,ATP1A2,AHCYL2,ATP13A4,RYR3,SLC25A18,SLC4A4,TRPM3,SLC1A3,CAMK2G
4.848e-05	-9.93	C4-dicarboxylate transport	biological process	GO:0015740	26	3	18204	50	SLC1A3,SLC25A18,SLC1A2
5.002e-05	-9.90	LRRC7 (leucine rich repeat containing 7)	protein interactions	57554	28	3	19454	50	ERBB4,CAMK2G,CTNND2
5.229e-05	-9.86	anatomical structure morphogenesis	biological process	GO:0009653	2225	17	18204	50	ERBB4,CLU,TNIK,SOX5,CDH20,NFIA,GPM6A,GLUL,QKI,FGFR3,SLC1A3,CTNNA2,CTNND2,RORA,ABLIM1,PARD3,PREX2
5.266e-05	-9.85	generation of neurons	biological process	GO:0048699	1158	12	18204	50	RORA,NTM,PARD3,NFIA,GPM6A,PREX2,TNIK,ERBB4,SLC1A3,CTNNA2,SOX5,CTNND2
5.769e-05	-9.76	cell periphery	cellular component	GO:0071944	6020	29	19108	49	ZNRF3,NKAIN3,TRPM3,RYR3,TNIK,SLC1A2,ATP13A4,CADM1,NTM,SLC4A4,CST3,ATP1A2,HPSE2,CDH20,CTNNA2,CLU,GLUL,PARD3,GPM6A,ERBB4,COL5A3,CTNND2,LSAMP,DOCK4,DTNA,PREX2,FGFR3,SLC1A3,GPC5
6.099e-05	-9.70	amino acid:monoatomic cation symporter activity	molecular function	GO:0005416	29	3	18094	48	SLC1A2,SLC1A3,SLC25A18
6.856e-05	-9.59	glutamate:sodium symporter activity	molecular function	GO:0015501	5	2	18094	48	SLC1A3,SLC1A2
6.856e-05	-9.59	high-affinity L-glutamate transmembrane transporter activity	molecular function	GO:0005314	5	2	18094	48	SLC1A3,SLC1A2
7.355e-05	-9.52	D-aspartate transmembrane transport	biological process	GO:0070777	5	2	18204	50	SLC1A2,SLC1A3
7.355e-05	-9.52	D-aspartate import across plasma membrane	biological process	GO:0070779	5	2	18204	50	SLC1A2,SLC1A3
7.513e-05	-9.50	neurotransmitter uptake	biological process	GO:0001504	30	3	18204	50	SLC1A3,ATP1A2,SLC1A2
7.513e-05	-9.50	L-glutamate import	biological process	GO:0051938	30	3	18204	50	SLC1A3,SLC25A18,SLC1A2
8.215e-05	-9.41	active monoatomic ion transmembrane transporter activity	molecular function	GO:0022853	274	6	18094	48	SLC1A3,ATP13A4,SLC1A2,SLC4A4,ATP1A2,SLC25A18
8.255e-05	-9.40	NTM (neurotrimin)	protein interactions	50863	33	3	19454	50	NTM,GPM6A,LSAMP
8.305e-05	-9.40	cell junction	cellular component	GO:0030054	2224	16	19108	49	ATP1A2,NFIA,SLC1A2,CDH20,CTNNA2,TNIK,QKI,CLU,GPM6A,CADM1,PARD3,CTNND2,ERBB4,DTNA,SLC1A3,FGFR3
9.059e-05	-9.31	transport across blood-brain barrier	biological process	GO:0150104	86	4	18204	50	SLC1A2,SLC4A4,ATP1A2,SLC1A3
9.059e-05	-9.31	vascular transport	biological process	GO:0010232	86	4	18204	50	SLC4A4,SLC1A2,SLC1A3,ATP1A2
9.079e-05	-9.31	upper_aerodigestive_tract	COSMIC cancer mutations	upper_aerodigestive_tract	13181	48	16828	49	NKAIN3,DTNA,PARD3,SLC1A3,NHSL1,NDRG2,NPAS3,FGFR3,MSI2,NTM,RYR3,CADM1,ZBTB20,CAMK2G,RORA,TNIK,PTGDS,GLUL,SLC1A2,SLC4A4,CST3,TRPS1,ZNRF3,ABLIM1,LSAMP,CTNND2,TRPM3,PITPNC1,NFIA,GPC5,COL5A3,ATP1A2,SOX5,ATP13A4,MAML2,PREX2,FBXL7,GPM6A,DOCK4,CDH20,CLU,AHCYL2,HPSE2,ERBB4,QKI,SASH1,DAAM2,SLC25A18
9.646e-05	-9.25	central_nervous_system-cerebellum-primitive_neuroectodermal_tumour-medulloblastoma-SHH_subtype	COSMIC cancer mutations	central_nervous_system-cerebellum-primitive_neuroectodermal_tumour-medulloblastoma-SHH_subtype	653	9	16828	49	RYR3,PARD3,ERBB4,HPSE2,CTNND2,ABLIM1,NPAS3,CADM1,MAML2
9.759e-05	-9.23	SHH_subtype	COSMIC cancer mutations	SHH_subtype	654	9	16828	49	NPAS3,CADM1,MAML2,CTNND2,ABLIM1,HPSE2,RYR3,PARD3,ERBB4
1.101e-04	-9.11	D-amino acid transport	biological process	GO:0042940	6	2	18204	50	SLC1A3,SLC1A2
1.101e-04	-9.11	L-aspartate import across plasma membrane	biological process	GO:0140009	6	2	18204	50	SLC1A2,SLC1A3
1.139e-04	-9.08	plasma membrane	cellular component	GO:0005886	5538	27	19108	49	TNIK,SLC1A2,RYR3,NKAIN3,TRPM3,ZNRF3,CST3,SLC4A4,ATP13A4,CADM1,NTM,GLUL,CTNNA2,CDH20,HPSE2,ATP1A2,PREX2,FGFR3,GPC5,SLC1A3,LSAMP,DTNA,DOCK4,ERBB4,CTNND2,PARD3,GPM6A
1.149e-04	-9.07	plasma membrane bounded cell projection	cellular component	GO:0120025	2285	16	19108	49	CTNND2,CAMK2G,PARD3,NDRG2,GPM6A,CADM1,SLC1A3,DOCK4,DTNA,ATP1A2,ABLIM1,GLUL,CLU,CTNNA2,SLC1A2,AHCYL2
1.349e-04	-8.91	neuron differentiation	biological process	GO:0030182	1081	11	18204	50	NFIA,GPM6A,PREX2,RORA,NTM,PARD3,CTNNA2,CTNND2,ERBB4,TNIK,SLC1A3
1.378e-04	-8.89	monoatomic ion transmembrane transporter activity	molecular function	GO:0015075	752	9	18094	48	SLC25A18,TRPM3,ATP13A4,RYR3,SLC4A4,GPM6A,SLC1A2,SLC1A3,ATP1A2
1.437e-04	-8.85	inorganic cation transmembrane transporter activity	molecular function	GO:0022890	589	8	18094	48	RYR3,SLC4A4,TRPM3,SLC25A18,ATP1A2,SLC1A2,SLC1A3,GPM6A
1.487e-04	-8.81	Na-dicarboxylate_symporter_CS	interpro domains	IPR018107	7	2	18521	50	SLC1A3,SLC1A2
1.487e-04	-8.81	Na:dicarbo_symporter_sf	interpro domains	IPR036458	7	2	18521	50	SLC1A3,SLC1A2
1.487e-04	-8.81	Na-dicarboxylate_symporter	interpro domains	IPR001991	7	2	18521	50	SLC1A2,SLC1A3
1.515e-04	-8.79	FGFR1 (fibroblast growth factor receptor 1)	protein interactions	2260	611	8	19454	50	CLU,FGFR3,NHSL1,TNIK,PARD3,ABLIM1,AHCYL2,DTNA
1.534e-04	-8.78	metal ion transmembrane transporter activity	molecular function	GO:0046873	442	7	18094	48	TRPM3,RYR3,SLC4A4,SLC1A2,SLC1A3,ATP1A2,GPM6A
1.610e-04	-8.73	SDF	pfam domains	PF00375	7	2	17795	50	SLC1A3,SLC1A2
1.625e-04	-8.72	intestinal_adenocarcinoma	COSMIC cancer mutations	intestinal_adenocarcinoma	7225	34	16828	49	ATP1A2,NTM,RYR3,ATP13A4,SOX5,ZBTB20,MAML2,PREX2,FBXL7,RORA,TRPM3,PITPNC1,NFIA,PARD3,NHSL1,NPAS3,FGFR3,COL5A3,CST3,HPSE2,TRPS1,ERBB4,QKI,ZNRF3,SASH1,DAAM2,LSAMP,CTNND2,DOCK4,GLUL,CDH20,CLU,SLC1A2,SLC4A4
1.625e-04	-8.72	stomach-carcinoma-intestinal_adenocarcinoma	COSMIC cancer mutations	stomach-carcinoma-intestinal_adenocarcinoma	7225	34	16828	49	QKI,ZNRF3,ERBB4,CST3,TRPS1,HPSE2,CTNND2,LSAMP,SASH1,DAAM2,SLC4A4,CLU,SLC1A2,CDH20,GLUL,DOCK4,RYR3,ATP13A4,SOX5,NTM,ATP1A2,RORA,FBXL7,ZBTB20,MAML2,PREX2,PARD3,PITPNC1,NFIA,TRPM3,COL5A3,FGFR3,NPAS3,NHSL1
1.662e-04	-8.70	cellular response to alkaloid	biological process	GO:0071312	39	3	18204	50	SLC1A2,SLC1A3,RYR3
1.794e-04	-8.63	Sodium:dicarboxylate symporter	gene3d domains	1.10.3860.10	7	2	14470	43	SLC1A3,SLC1A2
1.810e-04	-8.62	lung-carcinoma-small_cell_carcinoma	COSMIC cancer mutations	lung-carcinoma-small_cell_carcinoma	9908	41	16828	49	AHCYL2,HPSE2,TRPS1,CST3,ERBB4,ZNRF3,QKI,SLC25A18,DAAM2,SASH1,ABLIM1,CTNND2,DOCK4,TNIK,CDH20,CLU,SLC4A4,ATP1A2,MSI2,TPD52L1,NTM,ATP13A4,RYR3,SOX5,MAML2,PREX2,CAMK2G,FBXL7,GPM6A,RORA,DTNA,NKAIN3,TRPM3,NFIA,PITPNC1,PARD3,NDRG2,GPC5,NPAS3,FGFR3,COL5A3
1.829e-04	-8.61	EDTRNSPORT	prints domains	PR00173	7	2	5227	16	SLC1A3,SLC1A2
1.838e-04	-8.60	small_cell_carcinoma	COSMIC cancer mutations	small_cell_carcinoma	9913	41	16828	49	CDH20,TNIK,DOCK4,SLC4A4,CLU,CST3,HPSE2,TRPS1,AHCYL2,QKI,ZNRF3,ERBB4,SASH1,SLC25A18,DAAM2,CTNND2,ABLIM1,TRPM3,NKAIN3,DTNA,PARD3,PITPNC1,NFIA,NPAS3,GPC5,NDRG2,COL5A3,FGFR3,MSI2,ATP1A2,ATP13A4,SOX5,RYR3,NTM,TPD52L1,GPM6A,CAMK2G,FBXL7,MAML2,PREX2,RORA
1.841e-04	-8.60	beta-catenin binding	molecular function	GO:0008013	107	4	18094	48	CTNNA2,RORA,CDH20,CTNND2
1.874e-04	-8.58	bone-tibia-other-chondroblastoma	COSMIC cancer mutations	bone-tibia-other-chondroblastoma	98	4	16828	49	CTNND2,LSAMP,GPM6A,NKAIN3
2.008e-04	-8.51	scalp	COSMIC cancer mutations	scalp	2110	16	16828	49	NFIA,SLC4A4,GPC5,FGFR3,COL5A3,ATP1A2,TRPS1,ERBB4,NTM,ATP13A4,SOX5,PREX2,CADM1,CAMK2G,RORA,LSAMP
2.035e-04	-8.50	cell projection	cellular component	GO:0042995	2398	16	19108	49	SLC1A2,CLU,ABLIM1,GLUL,CTNNA2,AHCYL2,ATP1A2,SLC1A3,DOCK4,DTNA,CTNND2,GPM6A,CADM1,PARD3,NDRG2,CAMK2G
2.183e-04	-8.43	NA_DICARBOXYL_SYMP_1	prosite domains	PS00713	7	2	12186	40	SLC1A3,SLC1A2
2.183e-04	-8.43	NA_DICARBOXYL_SYMP_2	prosite domains	PS00714	7	2	12186	40	SLC1A2,SLC1A3
2.282e-04	-8.39	bone-humerus-other-chondroblastoma	COSMIC cancer mutations	bone-humerus-other-chondroblastoma	301	6	16828	49	NKAIN3,AHCYL2,TPD52L1,SOX5,GPC5,GPM6A
2.304e-04	-8.38	LSAMP (limbic system associated membrane protein)	protein interactions	4045	9	2	19454	50	NTM,LSAMP
2.304e-04	-8.38	NEGR1 (neuronal growth regulator 1)	protein interactions	257194	9	2	19454	50	LSAMP,NTM
2.383e-04	-8.34	right_lower_lobe	COSMIC cancer mutations	right_lower_lobe	5692	29	16828	49	PARD3,TRPM3,NKAIN3,DTNA,COL5A3,GPC5,NPAS3,SLC1A3,SOX5,ATP13A4,RYR3,NTM,ATP1A2,FBXL7,GPM6A,MAML2,SLC4A4,CLU,CDH20,DOCK4,ZNRF3,ERBB4,CST3,HPSE2,TRPS1,AHCYL2,CTNND2,LSAMP,SLC25A18
2.383e-04	-8.34	lung-right_lower_lobe-carcinoma-adenocarcinoma	COSMIC cancer mutations	lung-right_lower_lobe-carcinoma-adenocarcinoma	5692	29	16828	49	PARD3,TRPM3,DTNA,NKAIN3,COL5A3,GPC5,NPAS3,SLC1A3,SOX5,RYR3,ATP13A4,NTM,ATP1A2,FBXL7,GPM6A,MAML2,SLC4A4,CLU,CDH20,DOCK4,ZNRF3,ERBB4,TRPS1,HPSE2,CST3,AHCYL2,CTNND2,LSAMP,SLC25A18
2.551e-04	-8.27	acidic amino acid transport	biological process	GO:0015800	45	3	18204	50	SLC1A2,SLC1A3,SLC25A18
2.594e-04	-8.26	solute:monoatomic cation symporter activity	molecular function	GO:0015294	117	4	18094	48	SLC1A3,SLC1A2,SLC4A4,SLC25A18
2.833e-04	-8.17	carcinoid-endocrine_tumour	COSMIC cancer mutations	carcinoid-endocrine_tumour	7752	35	16828	49	TNIK,CDH20,CLU,SLC1A2,SLC4A4,SASH1,SLC25A18,LSAMP,ABLIM1,CTNND2,AHCYL2,HPSE2,TRPS1,ERBB4,QKI,SLC1A3,NHSL1,GPC5,FGFR3,COL5A3,NKAIN3,TRPM3,PARD3,CADM1,MAML2,PREX2,CAMK2G,FBXL7,GPM6A,RORA,ATP1A2,TPD52L1,ATP13A4,RYR3,SOX5
3.003e-04	-8.11	monoatomic ion transmembrane transport	biological process	GO:0034220	804	9	18204	50	ATP13A4,SLC4A4,GPM6A,TRPM3,SLC25A18,SLC1A2,ATP1A2,RYR3,SLC1A3
3.068e-04	-8.09	RNF115 (ring finger protein 115)	protein interactions	27246	126	4	19454	50	GLUL,NDRG2,DOCK4,CST3
3.095e-04	-8.08	oesophagus-carcinoma	COSMIC cancer mutations	oesophagus-carcinoma	4269	24	16828	49	COL5A3,FGFR3,NHSL1,PARD3,NFIA,TRPM3,FBXL7,GPM6A,PREX2,ZBTB20,CADM1,ATP13A4,SOX5,RYR3,NTM,SLC4A4,CDH20,PTGDS,DOCK4,TNIK,CTNND2,DAAM2,TRPS1,HPSE2
3.117e-04	-8.07	monoatomic cation transmembrane transport	biological process	GO:0098655	636	8	18204	50	RYR3,SLC1A3,ATP1A2,SLC25A18,TRPM3,GPM6A,SLC4A4,ATP13A4
3.124e-04	-8.07	NAKATPASE	prints domains	PR00121	9	2	5227	16	ATP1A2,ATP13A4
3.165e-04	-8.06	central nervous system development	biological process	GO:0007417	995	10	18204	50	RORA,DAAM2,MSI2,CTNNA2,SLC1A2,NDRG2,ERBB4,CLU,QKI,ATP1A2
3.281e-04	-8.02	cellular response to cocaine	biological process	GO:0071314	10	2	18204	50	SLC1A3,SLC1A2
3.318e-04	-8.01	autonomic_ganglia	COSMIC cancer mutations	autonomic_ganglia	4005	23	16828	49	DOCK4,TNIK,NFIA,SLC1A2,PITPNC1,SLC4A4,PARD3,NHSL1,NPAS3,FGFR3,COL5A3,ATP1A2,TRPS1,ERBB4,ZNRF3,RYR3,PREX2,MAML2,FBXL7,CAMK2G,GPM6A,SASH1,CTNND2
3.346e-04	-8.00	central_nervous_system-brainstem-glioma-oligoastrocytoma_Grade_III	COSMIC cancer mutations	central_nervous_system-brainstem-glioma-oligoastrocytoma_Grade_III	114	4	16828	49	SOX5,RYR3,SLC1A2,PREX2
3.488e-04	-7.96	pharynx	COSMIC cancer mutations	pharynx	2696	18	16828	49	NHSL1,NPAS3,GPC5,FGFR3,DTNA,DOCK4,SLC1A2,NFIA,PITPNC1,CLU,SLC4A4,PREX2,DAAM2,CTNND2,ATP1A2,RYR3,ATP13A4,QKI
3.988e-04	-7.83	NTRK2 (neurotrophic receptor tyrosine kinase 2)	protein interactions	4915	135	4	19454	50	ERBB4,PARD3,ABLIM1,DTNA
4.003e-04	-7.82	L-glutamate import across plasma membrane	biological process	GO:0098712	11	2	18204	50	SLC1A2,SLC1A3
4.118e-04	-7.79	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-chronic_lymphocytic_leukaemia-small_lymphocytic_lymphoma	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-chronic_lymphocytic_leukaemia-small_lymphocytic_lymphoma	3511	21	16828	49	RYR3,ZNRF3,ERBB4,MSI2,HPSE2,CTNND2,LSAMP,DAAM2,FBXL7,PREX2,PARD3,SLC4A4,PITPNC1,CLU,TRPM3,TNIK,DOCK4,DTNA,GPC5,NPAS3,SLC1A3
4.118e-04	-7.79	chronic_lymphocytic_leukaemia-small_lymphocytic_lymphoma	COSMIC cancer mutations	chronic_lymphocytic_leukaemia-small_lymphocytic_lymphoma	3511	21	16828	49	NPAS3,GPC5,SLC1A3,SLC4A4,PARD3,PITPNC1,CLU,TRPM3,TNIK,DTNA,DOCK4,CTNND2,LSAMP,FBXL7,DAAM2,PREX2,RYR3,ZNRF3,ERBB4,MSI2,HPSE2
4.695e-04	-7.66	Bicarbonate transporters	REACTOME pathways	R-HSA-425381	10	2	10285	34	SLC4A4,AHCYL2
5.266e-04	-7.55	inorganic molecular entity transmembrane transporter activity	molecular function	GO:0015318	714	8	18094	48	SLC25A18,TRPM3,RYR3,SLC4A4,GPM6A,SLC1A2,SLC1A3,ATP1A2
5.687e-04	-7.47	Ion channel transport	REACTOME pathways	R-HSA-983712	209	5	10285	34	RYR3,TRPM3,CAMK2G,ATP1A2,ATP13A4
5.776e-04	-7.46	PLXNA4 (plexin A4)	protein interactions	91584	14	2	19454	50	CLU,GPM6A
5.776e-04	-7.46	DACT2 (dishevelled binding antagonist of beta catenin 2)	protein interactions	168002	14	2	19454	50	ZBTB20,CAMK2G
6.143e-04	-7.40	gallbladder	COSMIC cancer mutations	gallbladder	2821	18	16828	49	RYR3,ZNRF3,ERBB4,TPD52L1,TRPS1,CTNND2,SASH1,PREX2,SLC4A4,PARD3,CLU,PITPNC1,TRPM3,TNIK,NKAIN3,COL5A3,FGFR3,NHSL1
6.143e-04	-7.40	biliary_tract-gallbladder-carcinoma-adenocarcinoma	COSMIC cancer mutations	biliary_tract-gallbladder-carcinoma-adenocarcinoma	2821	18	16828	49	TRPM3,TNIK,NKAIN3,SLC4A4,PARD3,CLU,PITPNC1,NHSL1,COL5A3,FGFR3,TRPS1,ZNRF3,RYR3,TPD52L1,ERBB4,SASH1,PREX2,CTNND2
6.239e-04	-7.38	upper_aerodigestive_tract-pharynx-carcinoma-nasopharyngeal_carcinoma	COSMIC cancer mutations	upper_aerodigestive_tract-pharynx-carcinoma-nasopharyngeal_carcinoma	1425	12	16828	49	FGFR3,NHSL1,SLC4A4,NFIA,SLC1A2,PITPNC1,CLU,CTNND2,PREX2,ATP13A4,QKI,ATP1A2
6.239e-04	-7.38	nasopharyngeal_carcinoma	COSMIC cancer mutations	nasopharyngeal_carcinoma	1425	12	16828	49	ATP1A2,QKI,ATP13A4,PREX2,CTNND2,SLC4A4,SLC1A2,NFIA,CLU,PITPNC1,NHSL1,FGFR3
6.323e-04	-7.37	symporter activity	molecular function	GO:0015293	148	4	18094	48	SLC4A4,SLC1A3,SLC1A2,SLC25A18
6.556e-04	-7.33	Ig_3	pfam domains	PF13927	141	4	17795	50	NTM,CADM1,LSAMP,FGFR3
6.588e-04	-7.33	sodium ion export across plasma membrane	biological process	GO:0036376	14	2	18204	50	ATP1A2,SLC4A4
6.654e-04	-7.32	TIAM2 (TIAM Rac1 associated GEF 2)	protein interactions	26230	15	2	19454	50	PARD3,TNIK
6.998e-04	-7.26	YWHAB (tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein beta)	protein interactions	7529	965	9	19454	50	PITPNC1,PARD3,DOCK4,FGFR3,NHSL1,ABLIM1,SASH1,CAMK2G,TPD52L1
7.080e-04	-7.25	astrocytoma_Grade_I	COSMIC cancer mutations	astrocytoma_Grade_I	139	4	16828	49	GPC5,QKI,PARD3,FGFR3
7.130e-04	-7.25	L-amino acid transmembrane transporter activity	molecular function	GO:0015179	66	3	18094	48	SLC25A18,SLC1A3,SLC1A2
7.220e-04	-7.23	dendrite morphogenesis	biological process	GO:0048813	64	3	18204	50	CTNNA2,PREX2,CTNND2
7.502e-04	-7.20	haematopoietic_and_lymphoid_tissue-haematopoietic_neoplasm-mast_cell_neoplasm	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue-haematopoietic_neoplasm-mast_cell_neoplasm	248	5	16828	49	GPC5,HPSE2,NPAS3,NFIA,ERBB4
7.502e-04	-7.20	mast_cell_neoplasm	COSMIC cancer mutations	mast_cell_neoplasm	248	5	16828	49	NFIA,ERBB4,HPSE2,GPC5,NPAS3
7.899e-04	-7.14	L-alpha-amino acid transmembrane transport	biological process	GO:1902475	66	3	18204	50	SLC1A3,SLC25A18,SLC1A2
8.074e-04	-7.12	PAK6 (p21 (RAC1) activated kinase 6)	protein interactions	56924	71	3	19454	50	TPD52L1,CAMK2G,AHCYL2
8.077e-04	-7.12	sodium ion transmembrane transporter activity	molecular function	GO:0015081	158	4	18094	48	SLC1A2,SLC1A3,ATP1A2,SLC4A4
8.086e-04	-7.12	human chr3q13.31	chromosome location	human chr3q13.31	22	2	26134	50	LSAMP,ZBTB20
8.118e-04	-7.12	Ion homeostasis	REACTOME pathways	R-HSA-5578775	56	3	10285	34	RYR3,CAMK2G,ATP1A2
8.327e-04	-7.09	autonomic_ganglia-neuroblastoma	COSMIC cancer mutations	autonomic_ganglia-neuroblastoma	3970	22	16828	49	PARD3,SLC4A4,PITPNC1,SLC1A2,NFIA,TNIK,DOCK4,COL5A3,FGFR3,NPAS3,RYR3,ZNRF3,ERBB4,TRPS1,ATP1A2,CTNND2,SASH1,CAMK2G,GPM6A,FBXL7,MAML2,PREX2
8.357e-04	-7.09	neuroblastoma	COSMIC cancer mutations	neuroblastoma	3971	22	16828	49	NPAS3,COL5A3,FGFR3,TNIK,DOCK4,PARD3,SLC4A4,PITPNC1,NFIA,SLC1A2,SASH1,GPM6A,FBXL7,CAMK2G,MAML2,PREX2,CTNND2,TRPS1,ATP1A2,RYR3,ZNRF3,ERBB4
8.657e-04	-7.05	asymmetric cell division	biological process	GO:0008356	16	2	18204	50	SOX5,PARD3
8.681e-04	-7.05	lymphoid_neoplasm	COSMIC cancer mutations	lymphoid_neoplasm	12233	45	16828	49	CTNND2,LSAMP,ABLIM1,TRPS1,ZNRF3,TNIK,SLC4A4,SLC1A2,CAMK2G,CADM1,ZBTB20,RORA,MSI2,RYR3,NTM,TPD52L1,NPAS3,SLC1A3,NHSL1,FGFR3,NKAIN3,DTNA,PARD3,SASH1,DAAM2,SLC25A18,HPSE2,AHCYL2,QKI,ERBB4,CDH20,DOCK4,CLU,FBXL7,GPM6A,PREX2,MAML2,ATP1A2,SOX5,ATP13A4,GPC5,COL5A3,TRPM3,PITPNC1,NFIA
8.927e-04	-7.02	vascular process in circulatory system	biological process	GO:0003018	273	5	18204	50	SLC1A2,SLC4A4,DOCK4,ATP1A2,SLC1A3
8.996e-04	-7.01	Ion transport by P-type ATPases	REACTOME pathways	R-HSA-936837	58	3	10285	34	ATP1A2,CAMK2G,ATP13A4
9.311e-04	-6.98	cell differentiation	biological process	GO:0030154	3645	20	18204	50	SLC1A3,FGFR3,QKI,CTNND2,NDRG2,CTNNA2,CAMK2G,MSI2,PARD3,NTM,RORA,PREX2,NHSL1,ERBB4,CADM1,CLU,TNIK,SOX5,GPM6A,NFIA
9.412e-04	-6.97	cellular developmental process	biological process	GO:0048869	3648	20	18204	50	PREX2,RORA,NTM,PARD3,MSI2,CTNNA2,CAMK2G,CTNND2,NDRG2,QKI,FGFR3,SLC1A3,NFIA,GPM6A,SOX5,NHSL1,ERBB4,CADM1,CLU,TNIK
9.592e-04	-6.95	humerus	COSMIC cancer mutations	humerus	546	7	16828	49	GPM6A,GPC5,NKAIN3,AHCYL2,DOCK4,SOX5,TPD52L1
9.648e-04	-6.94	NECTIN1 (nectin cell adhesion molecule 1)	protein interactions	5818	18	2	19454	50	FGFR3,PARD3
9.763e-04	-6.93	oligoastrocytoma_Grade_III	COSMIC cancer mutations	oligoastrocytoma_Grade_III	263	5	16828	49	PREX2,FGFR3,SLC1A2,SOX5,RYR3
1.022e-03	-6.89	Htt (huntingtin)	protein interactions	15194	77	3	19454	50	NTM,GPM6A,LSAMP
1.033e-03	-6.88	regulation of multicellular organismal process	biological process	GO:0051239	3113	18	18204	50	CST3,DOCK4,TRPS1,PTGDS,SOX5,CLU,CADM1,ERBB4,RORA,DAAM2,PARD3,CAMK2G,ZBTB20,NDRG2,SASH1,GLUL,QKI,ATP1A2
1.043e-03	-6.87	synapse	cellular component	GO:0045202	1473	11	19108	49	DTNA,SLC1A3,CADM1,GPM6A,ERBB4,CTNND2,CLU,QKI,TNIK,SLC1A2,ATP1A2
1.048e-03	-6.86	Wnt signaling pathway	biological process	GO:0016055	283	5	18204	50	NDRG2,CTNND2,DAAM2,TNIK,ZNRF3
1.053e-03	-6.86	LCK (LCK proto-oncogene, Src family tyrosine kinase)	protein interactions	3932	455	6	19454	50	ERBB4,SLC25A18,CTNND2,PARD3,CAMK2G,DTNA
1.061e-03	-6.85	monoatomic cation transport	biological process	GO:0006812	766	8	18204	50	TRPM3,SLC25A18,SLC4A4,ATP13A4,GPM6A,SLC1A3,RYR3,ATP1A2
1.061e-03	-6.85	ANKRD40 (ankyrin repeat domain 40)	protein interactions	91369	78	3	19454	50	SOX5,MSI2,SLC25A18
1.063e-03	-6.85	ATPase_P-typ_cation-transptr_N	interpro domains	IPR004014	18	2	18521	50	ATP1A2,ATP13A4
1.069e-03	-6.84	oesophagus-carcinoma-squamous_cell_carcinoma	COSMIC cancer mutations	oesophagus-carcinoma-squamous_cell_carcinoma	6486	30	16828	49	ATP13A4,RYR3,SOX5,ATP1A2,GPM6A,FBXL7,CADM1,ZBTB20,PREX2,MAML2,PARD3,PITPNC1,TRPM3,COL5A3,FGFR3,GPC5,NPAS3,NDRG2,ERBB4,HPSE2,TRPS1,CTNND2,ABLIM1,SASH1,DAAM2,SLC25A18,SLC4A4,GLUL,TNIK,DOCK4
1.082e-03	-6.83	active transmembrane transporter activity	molecular function	GO:0022804	444	6	18094	48	SLC25A18,SLC4A4,ATP13A4,ATP1A2,SLC1A3,SLC1A2
1.096e-03	-6.82	transporter activity	molecular function	GO:0005215	1211	10	18094	48	ATP13A4,TRPM3,PITPNC1,SLC4A4,RYR3,SLC25A18,SLC1A3,SLC1A2,ATP1A2,GPM6A
1.112e-03	-6.80	monoatomic ion transport	biological process	GO:0006811	964	9	18204	50	ATP1A2,SLC1A3,RYR3,SLC1A2,SLC25A18,TRPM3,GPM6A,ATP13A4,SLC4A4
1.150e-03	-6.77	Cation_ATPase_N	pfam domains	PF00690	18	2	17795	50	ATP1A2,ATP13A4
1.171e-03	-6.75	EPHA4 (EPH receptor A4)	protein interactions	2043	180	4	19454	50	CTNNA2,AHCYL2,PARD3,FGFR3
1.172e-03	-6.75	C11orf52 (chromosome 11 open reading frame 52)	protein interactions	91894	310	5	19454	50	TNIK,PARD3,ABLIM1,AHCYL2,DTNA
1.194e-03	-6.73	PDZD2 (PDZ domain containing 2)	protein interactions	23037	20	2	19454	50	CST3,CTNND2
1.215e-03	-6.71	central_nervous_system-brain-primitive_neuroectodermal_tumour-medulloblastoma-large_cell	COSMIC cancer mutations	central_nervous_system-brain-primitive_neuroectodermal_tumour-medulloblastoma-large_cell	1117	10	16828	49	ATP13A4,QKI,SOX5,RYR3,PARD3,SLC1A2,ERBB4,CDH20,DOCK4,GPC5
1.226e-03	-6.70	GSC (goosecoid homeobox)	protein interactions	145258	82	3	19454	50	NFIA,TRPS1,SOX5
1.247e-03	-6.69	solute:sodium symporter activity	molecular function	GO:0015370	80	3	18094	48	SLC4A4,SLC1A2,SLC1A3
1.283e-03	-6.66	dicarboxylic acid transport	biological process	GO:0006835	78	3	18204	50	SLC25A18,SLC1A3,SLC1A2
1.295e-03	-6.65	stomach-carcinoma-diffuse_adenocarcinoma	COSMIC cancer mutations	stomach-carcinoma-diffuse_adenocarcinoma	4383	23	16828	49	ABLIM1,CTNND2,CADM1,PREX2,SASH1,DAAM2,GPM6A,ERBB4,SOX5,QKI,RYR3,ZNRF3,ATP1A2,TRPS1,FGFR3,NHSL1,SLC1A3,CLU,PARD3,DTNA,DOCK4,TRPM3,GLUL
1.295e-03	-6.65	diffuse_adenocarcinoma	COSMIC cancer mutations	diffuse_adenocarcinoma	4383	23	16828	49	ATP1A2,TRPS1,ERBB4,ZNRF3,QKI,SOX5,RYR3,PREX2,CADM1,DAAM2,GPM6A,SASH1,ABLIM1,CTNND2,DOCK4,DTNA,GLUL,TRPM3,CLU,PARD3,SLC1A3,NHSL1,FGFR3
1.361e-03	-6.60	adherens junction	cellular component	GO:0005912	188	4	19108	49	CTNNA2,CDH20,CTNND2,PARD3
1.411e-03	-6.56	inorganic cation transmembrane transport	biological process	GO:0098662	618	7	18204	50	SLC25A18,TRPM3,GPM6A,SLC4A4,SLC1A3,RYR3,ATP1A2
1.502e-03	-6.50	positive regulation of purine nucleotide catabolic process	biological process	GO:0033123	21	2	18204	50	SLC4A4,ZBTB20
1.502e-03	-6.50	positive regulation of glycolytic process	biological process	GO:0045821	21	2	18204	50	SLC4A4,ZBTB20
1.502e-03	-6.50	positive regulation of nucleotide catabolic process	biological process	GO:0030813	21	2	18204	50	ZBTB20,SLC4A4
1.536e-03	-6.48	PDZ domain binding	molecular function	GO:0030165	86	3	18094	48	DTNA,DOCK4,CADM1
1.550e-03	-6.47	Cation_ATPase_N	smart domains	SM00831	16	2	9717	36	ATP1A2,ATP13A4
1.582e-03	-6.45	TIMM10B (translocase of inner mitochondrial membrane 10B)	protein interactions	26515	23	2	19454	50	HPSE2,MSI2
1.582e-03	-6.45	Rbm38 (RNA binding motif protein 38)	protein interactions	56190	23	2	19454	50	QKI,MSI2
1.589e-03	-6.44	L-amino acid transport	biological process	GO:0015807	84	3	18204	50	SLC1A2,SLC1A3,SLC25A18
1.649e-03	-6.41	intracellular sodium ion homeostasis	biological process	GO:0006883	22	2	18204	50	ATP1A2,SLC1A3
1.649e-03	-6.41	negative regulation of muscle contraction	biological process	GO:0045932	22	2	18204	50	DOCK4,ATP1A2
1.683e-03	-6.39	amino acid:sodium symporter activity	molecular function	GO:0005283	23	2	18094	48	SLC1A3,SLC1A2
1.688e-03	-6.38	forearm	COSMIC cancer mutations	forearm	81	3	16828	49	FGFR3,ERBB4,PREX2
1.723e-03	-6.36	LNP1 (leukemia NUP98 fusion partner 1)	protein interactions	348801	24	2	19454	50	AHCYL2,GLUL
1.781e-03	-6.33	ovary-carcinoma-serous_carcinoma	COSMIC cancer mutations	ovary-carcinoma-serous_carcinoma	10710	41	16828	49	QKI,ZNRF3,ERBB4,CST3,HPSE2,TRPS1,AHCYL2,CTNND2,LSAMP,SASH1,DAAM2,SLC4A4,CLU,SLC1A2,PTGDS,GLUL,CDH20,TNIK,DOCK4,RYR3,SOX5,ATP13A4,NTM,MSI2,ATP1A2,RORA,CAMK2G,FBXL7,CADM1,ZBTB20,MAML2,PREX2,PARD3,TRPM3,DTNA,COL5A3,FGFR3,GPC5,NPAS3,NHSL1,SLC1A3
1.832e-03	-6.30	P-type ion transporter activity	molecular function	GO:0015662	24	2	18094	48	ATP13A4,ATP1A2
1.832e-03	-6.30	P-type transmembrane transporter activity	molecular function	GO:0140358	24	2	18094	48	ATP1A2,ATP13A4
1.866e-03	-6.28	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-follicular_lymphoma	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-follicular_lymphoma	981	9	16828	49	SASH1,GPC5,LSAMP,RORA,CTNND2,NKAIN3,HPSE2,SOX5,PARD3
1.888e-03	-6.27	UTRN (utrophin)	protein interactions	7402	205	4	19454	50	FGFR3,PARD3,SASH1,DTNA
1.911e-03	-6.26	cell-cell junction	cellular component	GO:0005911	513	6	19108	49	CTNND2,CTNNA2,CDH20,CADM1,ATP1A2,PARD3
1.913e-03	-6.26	human chr6q24.3-q25.1	chromosome location	human chr6q24.3-q25.1	1	1	26134	50	SASH1
1.913e-03	-6.26	human chr9q21.12-q21.13	chromosome location	human chr9q21.12-q21.13	1	1	26134	50	TRPM3
1.913e-03	-6.26	human chr15q13.3-q14	chromosome location	human chr15q13.3-q14	1	1	26134	50	RYR3
1.913e-03	-6.26	human chr10p11.22-p11.21	chromosome location	human chr10p11.22-p11.21	1	1	26134	50	PARD3
1.913e-03	-6.26	human chr3q26.2-q26.31	chromosome location	human chr3q26.2-q26.31	1	1	26134	50	TNIK
2.018e-03	-6.21	back	COSMIC cancer mutations	back	310	5	16828	49	FGFR3,ERBB4,TNIK,PREX2,ATP1A2
2.021e-03	-6.20	skin-face-malignant_melanoma-lentigo_maligna	COSMIC cancer mutations	skin-face-malignant_melanoma-lentigo_maligna	23	2	16828	49	PREX2,FGFR3
2.062e-03	-6.18	neuron projection morphogenesis	biological process	GO:0048812	486	6	18204	50	TNIK,CTNND2,CTNNA2,PARD3,PREX2,GPM6A
2.142e-03	-6.15	HS-GAG degradation	REACTOME pathways	R-HSA-2024096	21	2	10285	34	GPC5,HPSE2
2.152e-03	-6.14	extrinsic component of plasma membrane	cellular component	GO:0019897	100	3	19108	49	CTNNA2,CDH20,DTNA
2.171e-03	-6.13	plasma membrane bounded cell projection morphogenesis	biological process	GO:0120039	491	6	18204	50	PARD3,GPM6A,PREX2,TNIK,CTNNA2,CTNND2
2.181e-03	-6.13	KCNJ12 (potassium inwardly rectifying channel subfamily J member 12)	protein interactions	3768	27	2	19454	50	ABLIM1,DTNA
2.181e-03	-6.13	MBNL2 (muscleblind like splicing regulator 2)	protein interactions	10150	27	2	19454	50	QKI,MSI2
2.185e-03	-6.13	extremity	COSMIC cancer mutations	extremity	1876	13	16828	49	FGFR3,COL5A3,DOCK4,CDH20,PITPNC1,PARD3,PREX2,SASH1,FBXL7,HPSE2,ERBB4,ATP13A4,RYR3
2.185e-03	-6.13	LYN (LYN proto-oncogene, Src family tyrosine kinase)	protein interactions	4067	713	7	19454	50	MSI2,SLC1A3,ABLIM1,DTNA,ERBB4,TNIK,PARD3
2.189e-03	-6.12	TRIM67 (tripartite motif containing 67)	protein interactions	440730	4804	22	19454	50	CTNND2,ATP1A2,QKI,SLC4A4,CST3,GLUL,NTM,DOCK4,SLC1A3,CAMK2G,DTNA,AHCYL2,CTNNA2,CADM1,MSI2,PARD3,TNIK,PITPNC1,GPM6A,LSAMP,CLU,SLC25A18
2.195e-03	-6.12	neuron development	biological process	GO:0048666	859	8	18204	50	PREX2,CTNND2,GPM6A,CTNNA2,PARD3,SLC1A3,NTM,TNIK
2.198e-03	-6.12	follicular_lymphoma	COSMIC cancer mutations	follicular_lymphoma	1209	10	16828	49	SASH1,GPC5,CTNND2,LSAMP,RORA,HPSE2,TNIK,NKAIN3,SOX5,PARD3
2.217e-03	-6.11	glutamate dependent acid resistance	BIOCYC pathways	HUMAN_PWY0-1305	1	1	902	2	GLUL
2.217e-03	-6.11	L-glutamine biosynthesis I	BIOCYC pathways	META_GLNSYN-PWY	1	1	902	2	GLUL
2.217e-03	-6.11	glutamine biosynthesis	BIOCYC pathways	HUMAN_GLNSYN-PWY	1	1	902	2	GLUL
2.282e-03	-6.08	transmembrane transporter activity	molecular function	GO:0022857	1110	9	18094	48	SLC25A18,RYR3,SLC4A4,TRPM3,ATP13A4,GPM6A,ATP1A2,SLC1A2,SLC1A3
2.284e-03	-6.08	cell projection morphogenesis	biological process	GO:0048858	496	6	18204	50	GPM6A,PREX2,CTNND2,CTNNA2,PARD3,TNIK
2.302e-03	-6.07	Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour	COSMIC cancer mutations	Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour	7434	32	16828	49	SLC4A4,TNIK,DOCK4,PTGDS,GLUL,ERBB4,QKI,CST3,TRPS1,ABLIM1,CTNND2,SASH1,DAAM2,PARD3,NKAIN3,DTNA,TRPM3,FGFR3,COL5A3,SLC1A3,NPAS3,TPD52L1,SOX5,RYR3,ATP13A4,ATP1A2,RORA,ZBTB20,CADM1,MAML2,PREX2,CAMK2G
2.341e-03	-6.06	SLC-mediated transmembrane transport	REACTOME pathways	R-HSA-425407	287	5	10285	34	SLC1A2,SLC4A4,SLC25A18,SLC1A3,AHCYL2
2.366e-03	-6.05	amino acid transmembrane transporter activity	molecular function	GO:0015171	100	3	18094	48	SLC25A18,SLC1A2,SLC1A3
2.398e-03	-6.03	amino acid transmembrane transport	biological process	GO:0003333	97	3	18204	50	SLC1A3,SLC25A18,SLC1A2
2.455e-03	-6.01	NTRK3 (neurotrophic receptor tyrosine kinase 3)	protein interactions	4916	367	5	19454	50	AHCYL2,ABLIM1,PARD3,TNIK,CLU
2.478e-03	-6.00	Calcium-transporting ATPase, transmembrane domain	gene3d domains	1.20.1110.10	25	2	14470	43	ATP13A4,ATP1A2
2.484e-03	-6.00	regulation of non-canonical Wnt signaling pathway	biological process	GO:2000050	27	2	18204	50	DAAM2,ZNRF3
2.511e-03	-5.99	neck	COSMIC cancer mutations	neck	1231	10	16828	49	CTNND2,COL5A3,FGFR3,SASH1,GPC5,PREX2,ATP13A4,ERBB4,TRPM3,ATP1A2
2.564e-03	-5.97	perinuclear endoplasmic reticulum lumen	cellular component	GO:0099020	1	1	19108	49	CLU
2.570e-03	-5.96	Sh2b1 (SH2B adaptor protein 1)	protein interactions	20399	1	1	19454	50	FGFR3
2.570e-03	-5.96	Agtrap (angiotensin II, type I receptor-associated protein)	protein interactions	11610	1	1	19454	50	PITPNC1
2.570e-03	-5.96	fgf3.L (fibroblast growth factor 3 L homeolog)	protein interactions	373669	1	1	19454	50	FGFR3
2.609e-03	-5.95	Proximal tubule bicarbonate reclamation	KEGG pathways	ko04964	23	2	7161	24	ATP1A2,SLC4A4
2.609e-03	-5.95	Proximal tubule bicarbonate reclamation	KEGG pathways	hsa04964	23	2	7161	24	ATP1A2,SLC4A4
2.614e-03	-5.95	response to alkaloid	biological process	GO:0043279	100	3	18204	50	SLC1A2,RYR3,SLC1A3
2.653e-03	-5.93	internal N(7)-methylguanine-containing RNA reader activity	molecular function	GO:0160089	1	1	18094	48	QKI
2.670e-03	-5.93	glial cell proliferation	biological process	GO:0014009	28	2	18204	50	CLU,NFIA
2.698e-03	-5.92	FKBP1A (FKBP prolyl isomerase 1A)	protein interactions	2280	108	3	19454	50	ERBB4,MSI2,RYR3
2.698e-03	-5.92	EN1 (engrailed homeobox 1)	protein interactions	2019	108	3	19454	50	AHCYL2,TRPS1,NFIA
2.700e-03	-5.91	Clusterin_CS	interpro domains	IPR033986	1	1	18521	50	CLU
2.700e-03	-5.91	STAR_dimer	interpro domains	IPR032377	1	1	18521	50	QKI
2.700e-03	-5.91	DHR2_DOCK4	interpro domains	IPR037014	1	1	18521	50	DOCK4
2.700e-03	-5.91	Clusterin	interpro domains	IPR016016	1	1	18521	50	CLU
2.700e-03	-5.91	SASH1_SAM_repeat2	interpro domains	IPR037630	1	1	18521	50	SASH1
2.700e-03	-5.91	TRPS1	interpro domains	IPR028440	1	1	18521	50	TRPS1
2.700e-03	-5.91	ZNRF3_Znf_RING	interpro domains	IPR045903	1	1	18521	50	ZNRF3
2.700e-03	-5.91	SASH1_SH3	interpro domains	IPR035720	1	1	18521	50	SASH1
2.700e-03	-5.91	SASH1_SAM_repeat1	interpro domains	IPR037627	1	1	18521	50	SASH1
2.700e-03	-5.91	Gln_synth_N_conserv_site	interpro domains	IPR027302	1	1	18521	50	GLUL
2.700e-03	-5.91	Quaking_NLS	interpro domains	IPR032367	1	1	18521	50	QKI
2.700e-03	-5.91	Rex2_DEP_1	interpro domains	IPR037367	1	1	18521	50	PREX2
2.700e-03	-5.91	Gln_synth_gly_rich_site	interpro domains	IPR027303	1	1	18521	50	GLUL
2.700e-03	-5.91	MAML2_TAD	interpro domains	IPR048452	1	1	18521	50	MAML2
2.700e-03	-5.91	DOCK4_SH3	interpro domains	IPR035769	1	1	18521	50	DOCK4
2.709e-03	-5.91	large_intestine-caecum-carcinoma-adenocarcinoma	COSMIC cancer mutations	large_intestine-caecum-carcinoma-adenocarcinoma	14236	48	16828	49	CLU,CDH20,DOCK4,SLC25A18,DAAM2,SASH1,QKI,ERBB4,HPSE2,AHCYL2,COL5A3,GPC5,NFIA,PITPNC1,TRPM3,GPM6A,FBXL7,MAML2,PREX2,ATP13A4,SOX5,ATP1A2,SLC4A4,SLC1A2,GLUL,PTGDS,TNIK,CTNND2,ABLIM1,LSAMP,ZNRF3,TRPS1,CST3,FGFR3,NPAS3,NHSL1,NDRG2,SLC1A3,PARD3,DTNA,NKAIN3,RORA,CAMK2G,CADM1,ZBTB20,RYR3,TPD52L1,NTM
2.718e-03	-5.91	NR3C1 (nuclear receptor subfamily 3 group C member 1)	protein interactions	2908	950	8	19454	50	CADM1,SLC1A3,CTNND2,CAMK2G,TRPS1,NFIA,ZBTB20,ATP13A4
2.747e-03	-5.90	negative regulation of elastin catabolic process	biological process	GO:0060311	1	1	18204	50	CST3
2.747e-03	-5.90	olfactory cortex development	biological process	GO:0021989	1	1	18204	50	ATP1A2
2.747e-03	-5.90	regulation of neuronal signal transduction	biological process	GO:1902847	1	1	18204	50	CLU
2.747e-03	-5.90	negative regulation of collagen catabolic process	biological process	GO:0010711	1	1	18204	50	CST3
2.747e-03	-5.90	positive regulation of neurofibrillary tangle assembly	biological process	GO:1902998	1	1	18204	50	CLU
2.747e-03	-5.90	negative regulation of calcium:sodium antiporter activity	biological process	GO:1903280	1	1	18204	50	ATP1A2
2.790e-03	-5.88	positive regulation of phosphorus metabolic process	biological process	GO:0010562	697	7	18204	50	SASH1,ZBTB20,TPD52L1,FGFR3,ERBB4,TNIK,SLC4A4
2.790e-03	-5.88	positive regulation of phosphate metabolic process	biological process	GO:0045937	697	7	18204	50	ZBTB20,SASH1,TNIK,ERBB4,FGFR3,TPD52L1,SLC4A4
2.797e-03	-5.88	Glutamate Neurotransmitter Release Cycle	REACTOME pathways	R-HSA-210500	24	2	10285	34	SLC1A2,SLC1A3
2.809e-03	-5.87	caecum	COSMIC cancer mutations	caecum	14248	48	16828	49	NTM,TPD52L1,RYR3,RORA,CADM1,ZBTB20,CAMK2G,PARD3,NKAIN3,DTNA,FGFR3,NHSL1,NDRG2,SLC1A3,NPAS3,ZNRF3,CST3,TRPS1,ABLIM1,LSAMP,CTNND2,SLC1A2,SLC4A4,TNIK,PTGDS,GLUL,SOX5,ATP13A4,ATP1A2,MAML2,PREX2,FBXL7,GPM6A,PITPNC1,NFIA,TRPM3,COL5A3,GPC5,ERBB4,QKI,AHCYL2,HPSE2,SASH1,DAAM2,SLC25A18,CLU,DOCK4,CDH20
2.810e-03	-5.87	MAML2_TAD	pfam domains	PF20804	1	1	17795	50	MAML2
2.810e-03	-5.87	Gln-synt_N	pfam domains	PF03951	1	1	17795	50	GLUL
2.810e-03	-5.87	FGFR3_TM	pfam domains	PF21165	1	1	17795	50	FGFR3
2.810e-03	-5.87	STAR_dimer	pfam domains	PF16544	1	1	17795	50	QKI
2.810e-03	-5.87	Quaking_NLS	pfam domains	PF16551	1	1	17795	50	QKI
2.857e-03	-5.86	cell body	cellular component	GO:0044297	556	6	19108	49	CTNND2,GPM6A,ATP1A2,SLC1A2,SLC1A3,GLUL
2.857e-03	-5.86	catenin complex	cellular component	GO:0016342	31	2	19108	49	CTNNA2,CDH20
2.870e-03	-5.85	SH2B1 (SH2B adaptor protein 1)	protein interactions	25970	31	2	19454	50	ERBB4,FGFR3
2.870e-03	-5.85	SH2D1B (SH2 domain containing 1B)	protein interactions	117157	31	2	19454	50	ABLIM1,ERBB4
2.972e-03	-5.82	-	gene3d domains	6.10.250.880	1	1	14470	43	ERBB4
2.972e-03	-5.82	-	gene3d domains	6.10.250.1740	1	1	14470	43	FGFR3
2.972e-03	-5.82	-	gene3d domains	1.20.5.4010	1	1	14470	43	QKI
2.991e-03	-5.81	TBR1 (T-box brain transcription factor 1)	protein interactions	10716	112	3	19454	50	SOX5,TRPS1,NFIA
3.002e-03	-5.81	neural precursor cell proliferation	biological process	GO:0061351	105	3	18204	50	RORA,SOX5,NFIA
3.028e-03	-5.80	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-plasma_cell_myeloma	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-plasma_cell_myeloma	1263	10	16828	49	NTM,ATP13A4,RYR3,TNIK,HPSE2,TRPS1,ABLIM1,FGFR3,CTNND2,GPM6A
3.028e-03	-5.80	plasma_cell_myeloma	COSMIC cancer mutations	plasma_cell_myeloma	1263	10	16828	49	TRPS1,HPSE2,TNIK,RYR3,ATP13A4,NTM,GPM6A,CTNND2,ABLIM1,FGFR3
3.044e-03	-5.79	glial cell differentiation	biological process	GO:0010001	219	4	18204	50	CLU,QKI,PARD3,NFIA
3.132e-03	-5.77	acute_lymphoblastic_leukaemia	COSMIC cancer mutations	acute_lymphoblastic_leukaemia	2197	14	16828	49	CADM1,PREX2,DAAM2,SLC25A18,CAMK2G,ERBB4,SOX5,ATP1A2,TRPS1,FGFR3,NFIA,SLC4A4,TNIK,DTNA
3.210e-03	-5.74	Salivary secretion	KEGG pathways	ko04970	90	3	7161	24	CST3,RYR3,ATP1A2
3.210e-03	-5.74	Salivary secretion	KEGG pathways	hsa04970	90	3	7161	24	CST3,RYR3,ATP1A2
3.214e-03	-5.74	inorganic ion transmembrane transport	biological process	GO:0098660	715	7	18204	50	GPM6A,SLC4A4,SLC25A18,TRPM3,RYR3,SLC1A3,ATP1A2
3.219e-03	-5.74	skin-leg-malignant_melanoma-superficial_spreading	COSMIC cancer mutations	skin-leg-malignant_melanoma-superficial_spreading	210	4	16828	49	NTM,SLC4A4,COL5A3,ATP13A4
3.234e-03	-5.73	cell junction organization	biological process	GO:0034330	532	6	18204	50	NFIA,CTNND2,GPM6A,ERBB4,CDH20,PARD3
3.282e-03	-5.72	CLUSTERIN_1	prosite domains	PS00492	1	1	12186	40	CLU
3.282e-03	-5.72	GLNA_1	prosite domains	PS00180	1	1	12186	40	GLUL
3.282e-03	-5.72	GLNA_ATP	prosite domains	PS00181	1	1	12186	40	GLUL
3.282e-03	-5.72	CLUSTERIN_2	prosite domains	PS00493	1	1	12186	40	CLU
3.306e-03	-5.71	t(4;14) translocations of FGFR3	REACTOME pathways	R-HSA-2033515	1	1	10285	34	FGFR3
3.415e-03	-5.68	E1-E2_ATPase	pfam domains	PF00122	31	2	17795	50	ATP1A2,ATP13A4
3.430e-03	-5.68	lentigo_maligna	COSMIC cancer mutations	lentigo_maligna	30	2	16828	49	PREX2,FGFR3
3.430e-03	-5.68	skin-malignant_melanoma-acral_lentiginous	COSMIC cancer mutations	skin-malignant_melanoma-acral_lentiginous	30	2	16828	49	PREX2,FGFR3
3.468e-03	-5.66	pancreas-carcinoid-endocrine_tumour	COSMIC cancer mutations	pancreas-carcinoid-endocrine_tumour	7250	31	16828	49	NHSL1,SLC1A3,GPC5,FGFR3,COL5A3,NKAIN3,PARD3,CADM1,MAML2,PREX2,GPM6A,FBXL7,RORA,ATP1A2,TPD52L1,ATP13A4,RYR3,SOX5,CDH20,CLU,SLC1A2,SLC4A4,SASH1,SLC25A18,ABLIM1,LSAMP,CTNND2,AHCYL2,HPSE2,ERBB4,QKI
3.479e-03	-5.66	positive regulation of ATP metabolic process	biological process	GO:1903580	32	2	18204	50	ZBTB20,SLC4A4
3.479e-03	-5.66	transepithelial transport	biological process	GO:0070633	32	2	18204	50	SLC1A2,SLC1A3
3.531e-03	-5.65	central_nervous_system-cerebellum-glioma-astrocytoma_Grade_I	COSMIC cancer mutations	central_nervous_system-cerebellum-glioma-astrocytoma_Grade_I	105	3	16828	49	GPC5,PARD3,QKI
3.621e-03	-5.62	serous_carcinoma	COSMIC cancer mutations	serous_carcinoma	10987	41	16828	49	DOCK4,TNIK,CDH20,GLUL,PTGDS,SLC1A2,CLU,SLC4A4,AHCYL2,TRPS1,HPSE2,CST3,ERBB4,ZNRF3,QKI,DAAM2,SASH1,LSAMP,CTNND2,DTNA,TRPM3,PARD3,NHSL1,SLC1A3,GPC5,NPAS3,FGFR3,COL5A3,ATP1A2,MSI2,NTM,SOX5,RYR3,ATP13A4,PREX2,MAML2,ZBTB20,CADM1,CAMK2G,FBXL7,RORA
3.637e-03	-5.62	Cation_ATPase	pfam domains	PF13246	32	2	17795	50	ATP13A4,ATP1A2
3.688e-03	-5.60	calcium channel activity	molecular function	GO:0005262	117	3	18094	48	GPM6A,RYR3,TRPM3
3.692e-03	-5.60	dendrite development	biological process	GO:0016358	113	3	18204	50	CTNNA2,PREX2,CTNND2
3.697e-03	-5.60	response to auditory stimulus	biological process	GO:0010996	33	2	18204	50	SLC1A3,ATP1A2
3.801e-03	-5.57	regulation of phosphate metabolic process	biological process	GO:0019220	1154	9	18204	50	FGFR3,TPD52L1,ERBB4,CADM1,TNIK,SASH1,ZBTB20,PARD3,SLC4A4
3.823e-03	-5.57	regulation of phosphorus metabolic process	biological process	GO:0051174	1155	9	18204	50	ZBTB20,SASH1,TNIK,CADM1,ERBB4,FGFR3,TPD52L1,SLC4A4,PARD3
3.857e-03	-5.56	ZNRF1 (zinc and ring finger 1)	protein interactions	84937	36	2	19454	50	GLUL,ATP1A2
3.871e-03	-5.55	cell adhesion	biological process	GO:0007155	942	8	18204	50	PARD3,CDH20,NTM,CTNND2,LSAMP,CTNNA2,COL5A3,CADM1
3.878e-03	-5.55	organic acid:sodium symporter activity	molecular function	GO:0005343	35	2	18094	48	SLC1A2,SLC1A3
3.912e-03	-5.54	Ig_sub2	interpro domains	IPR003598	239	4	18521	50	FGFR3,LSAMP,CADM1,NTM
4.052e-03	-5.51	glial cell projection	cellular component	GO:0097386	37	2	19108	49	GLUL,SLC1A2
4.071e-03	-5.50	TRNAU1AP (tRNA selenocysteine 1 associated protein 1)	protein interactions	54952	37	2	19454	50	QKI,ZBTB20
4.071e-03	-5.50	HPCA (hippocalcin)	protein interactions	3208	37	2	19454	50	GPM6A,CST3
4.071e-03	-5.50	TH (tyrosine hydroxylase)	protein interactions	7054	37	2	19454	50	CAMK2G,DAAM2
4.071e-03	-5.50	MAGI2 (membrane associated guanylate kinase, WW and PDZ domain containing 2)	protein interactions	9863	37	2	19454	50	ERBB4,CTNND2
4.099e-03	-5.50	proteoglycan binding	molecular function	GO:0043394	36	2	18094	48	HPSE2,COL5A3
4.244e-03	-5.46	P_typ_ATPase_HD_dom	interpro domains	IPR044492	36	2	18521	50	ATP13A4,ATP1A2
4.244e-03	-5.46	P_typ_ATPase	interpro domains	IPR001757	36	2	18521	50	ATP1A2,ATP13A4
4.244e-03	-5.46	ATPase_P-typ_transduc_dom_A_sf	interpro domains	IPR008250	36	2	18521	50	ATP1A2,ATP13A4
4.244e-03	-5.46	ATPase_P-typ_cyto_dom_N	interpro domains	IPR023299	36	2	18521	50	ATP13A4,ATP1A2
4.244e-03	-5.46	ATPase_P-typ_P_site	interpro domains	IPR018303	36	2	18521	50	ATP1A2,ATP13A4
4.258e-03	-5.46	EPB41L4A (erythrocyte membrane protein band 4.1 like 4A)	protein interactions	64097	127	3	19454	50	PARD3,ABLIM1,DTNA
4.258e-03	-5.46	PAX9 (paired box 9)	protein interactions	5083	127	3	19454	50	QKI,TRPS1,NFIA
4.290e-03	-5.45	Pcbp1 (poly(rC) binding protein 1)	protein interactions	23983	38	2	19454	50	MSI2,QKI
4.370e-03	-5.43	striated muscle contraction	biological process	GO:0006941	120	3	18204	50	RYR3,ATP1A2,DTNA
4.391e-03	-5.43	central_nervous_system-parietal_lobe-glioma-astrocytoma_Grade_I	COSMIC cancer mutations	central_nervous_system-parietal_lobe-glioma-astrocytoma_Grade_I	34	2	16828	49	QKI,FGFR3
4.407e-03	-5.42	bone-Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour	COSMIC cancer mutations	bone-Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour	6023	27	16828	49	COL5A3,FGFR3,NPAS3,SLC1A3,PARD3,TRPM3,DTNA,NKAIN3,RORA,CAMK2G,PREX2,MAML2,CADM1,ZBTB20,ATP13A4,SOX5,RYR3,TPD52L1,ATP1A2,SLC4A4,DOCK4,CTNND2,ABLIM1,DAAM2,SASH1,ERBB4,CST3
4.413e-03	-5.42	arm	COSMIC cancer mutations	arm	1331	10	16828	49	NPAS3,ZBTB20,COL5A3,FGFR3,TRPS1,TRPM3,ATP1A2,SLC4A4,ERBB4,NTM
4.432e-03	-5.42	L-glutamate and L-glutamine biosynthesis	BIOCYC pathways	META_PWY-5505	2	1	902	2	GLUL
4.478e-03	-5.41	ATPase_P-typ_TM_dom_sf	interpro domains	IPR023298	37	2	18521	50	ATP13A4,ATP1A2
4.496e-03	-5.40	skin-face-carcinoma-squamous_cell_carcinoma	COSMIC cancer mutations	skin-face-carcinoma-squamous_cell_carcinoma	2036	13	16828	49	MSI2,TRPS1,ZNRF3,ERBB4,GPM6A,PREX2,ABLIM1,LSAMP,RORA,TRPM3,PARD3,GPC5,FGFR3
4.545e-03	-5.39	RSPH1 (radial spoke head component 1)	protein interactions	89765	130	3	19454	50	CADM1,CLU,GLUL
4.616e-03	-5.38	kidney-carcinoma-papillary_renal_cell_carcinoma	COSMIC cancer mutations	kidney-carcinoma-papillary_renal_cell_carcinoma	6364	28	16828	49	HPSE2,ERBB4,ZNRF3,SASH1,ABLIM1,CTNND2,TNIK,DOCK4,GLUL,CLU,SLC4A4,ATP1A2,NTM,RYR3,ATP13A4,SOX5,ZBTB20,CADM1,PREX2,MAML2,CAMK2G,RORA,TRPM3,PITPNC1,NFIA,PARD3,GPC5,FGFR3
4.616e-03	-5.38	papillary_renal_cell_carcinoma	COSMIC cancer mutations	papillary_renal_cell_carcinoma	6364	28	16828	49	PARD3,PITPNC1,NFIA,TRPM3,FGFR3,GPC5,SOX5,RYR3,ATP13A4,NTM,ATP1A2,RORA,CAMK2G,ZBTB20,CADM1,MAML2,PREX2,SLC4A4,CLU,GLUL,TNIK,DOCK4,ZNRF3,ERBB4,HPSE2,CTNND2,ABLIM1,SASH1
4.631e-03	-5.38	positive regulation of nucleotide metabolic process	biological process	GO:0045981	37	2	18204	50	SLC4A4,ZBTB20
4.631e-03	-5.38	positive regulation of purine nucleotide metabolic process	biological process	GO:1900544	37	2	18204	50	ZBTB20,SLC4A4
4.705e-03	-5.36	plasma membrane region	cellular component	GO:0098590	1278	9	19108	49	TNIK,SLC1A3,SLC1A2,PARD3,ATP1A2,GPM6A,CADM1,ERBB4,SLC4A4
4.744e-03	-5.35	DZIP1 (DAZ interacting zinc finger protein 1)	protein interactions	22873	40	2	19454	50	PARD3,CAMK2G
4.880e-03	-5.32	amino acid import across plasma membrane	biological process	GO:0089718	38	2	18204	50	SLC1A2,SLC1A3
4.912e-03	-5.32	central_nervous_system-thalamus-glioma-astrocytoma_Grade_I	COSMIC cancer mutations	central_nervous_system-thalamus-glioma-astrocytoma_Grade_I	36	2	16828	49	FGFR3,QKI
4.929e-03	-5.31	CATATPASE	prints domains	PR00119	35	2	5227	16	ATP13A4,ATP1A2
4.969e-03	-5.30	intracellular chemical homeostasis	biological process	GO:0055082	581	6	18204	50	ATP1A2,RYR3,SLC1A3,ZBTB20,ATP13A4,SLC4A4
4.980e-03	-5.30	RASSF7 (Ras association domain family member 7)	protein interactions	8045	41	2	19454	50	CLU,PARD3
4.988e-03	-5.30	salivary_gland-carcinoma	COSMIC cancer mutations	salivary_gland-carcinoma	383	5	16828	49	CAMK2G,TNIK,MAML2,FGFR3,ERBB4
4.988e-03	-5.30	upper_aerodigestive_tract-mouth-carcinoma-adenoid_cystic_carcinoma	COSMIC cancer mutations	upper_aerodigestive_tract-mouth-carcinoma-adenoid_cystic_carcinoma	383	5	16828	49	TNIK,MAML2,CAMK2G,FGFR3,ERBB4
4.988e-03	-5.30	upper_aerodigestive_tract-head_neck-carcinoma-adenoid_cystic_carcinoma	COSMIC cancer mutations	upper_aerodigestive_tract-head_neck-carcinoma-adenoid_cystic_carcinoma	383	5	16828	49	CAMK2G,MAML2,TNIK,ERBB4,FGFR3
4.988e-03	-5.30	upper_aerodigestive_tract-lymph_node-carcinoma-adenoid_cystic_carcinoma	COSMIC cancer mutations	upper_aerodigestive_tract-lymph_node-carcinoma-adenoid_cystic_carcinoma	383	5	16828	49	CAMK2G,MAML2,TNIK,ERBB4,FGFR3
4.988e-03	-5.30	upper_aerodigestive_tract-carcinoma	COSMIC cancer mutations	upper_aerodigestive_tract-carcinoma	383	5	16828	49	CAMK2G,MAML2,TNIK,ERBB4,FGFR3
5.049e-03	-5.29	Myo1c (myosin IC)	protein interactions	17913	135	3	19454	50	ABLIM1,CAMK2G,TRPS1
5.049e-03	-5.29	FOXP1 (forkhead box P1)	protein interactions	27086	135	3	19454	50	SASH1,SOX5,NFIA
5.097e-03	-5.28	Calcium-transporting ATPase, cytoplasmic domain N	gene3d domains	3.40.1110.10	36	2	14470	43	ATP1A2,ATP13A4
5.097e-03	-5.28	Calcium-transporting ATPase, cytoplasmic transduction domain A	gene3d domains	2.70.150.10	36	2	14470	43	ATP13A4,ATP1A2
5.134e-03	-5.27	cdh11.S (cadherin 11 S homeolog)	protein interactions	100337621	2	1	19454	50	ERBB4
5.134e-03	-5.27	ORF43 (ORF43)	protein interactions	4961497	2	1	19454	50	DAAM2
5.134e-03	-5.27	sodium ion homeostasis	biological process	GO:0055078	39	2	18204	50	ATP1A2,SLC1A3
5.134e-03	-5.27	olfactory lobe development	biological process	GO:0021988	39	2	18204	50	ERBB4,ATP1A2
5.184e-03	-5.26	central_nervous_system-third_ventricle-glioma-astrocytoma_Grade_I	COSMIC cancer mutations	central_nervous_system-third_ventricle-glioma-astrocytoma_Grade_I	37	2	16828	49	QKI,FGFR3
5.220e-03	-5.26	E7 (early protein)	protein interactions	1489425	42	2	19454	50	CLU,SASH1
5.231e-03	-5.25	myelination	biological process	GO:0042552	128	3	18204	50	PARD3,QKI,CLU
5.251e-03	-5.25	oligoastrocytoma_Grade_II	COSMIC cancer mutations	oligoastrocytoma_Grade_II	121	3	16828	49	DTNA,CDH20,FGFR3
5.299e-03	-5.24	heparanase activity	molecular function	GO:0030305	2	1	18094	48	HPSE2
5.299e-03	-5.24	ammonia ligase activity	molecular function	GO:0016211	2	1	18094	48	GLUL
5.299e-03	-5.24	glutamine synthetase activity	molecular function	GO:0004356	2	1	18094	48	GLUL
5.302e-03	-5.24	lung-left_upper_lobe-carcinoma-adenocarcinoma	COSMIC cancer mutations	lung-left_upper_lobe-carcinoma-adenocarcinoma	556	6	16828	49	CTNND2,FBXL7,RYR3,SLC4A4,ERBB4,TRPS1
5.339e-03	-5.23	skin-scalp-carcinoma-squamous_cell_carcinoma	COSMIC cancer mutations	skin-scalp-carcinoma-squamous_cell_carcinoma	1596	11	16828	49	SLC4A4,SOX5,ATP13A4,ATP1A2,TRPS1,RORA,FGFR3,LSAMP,COL5A3,CADM1,GPC5
5.366e-03	-5.23	NFIB (nuclear factor I B)	protein interactions	4781	138	3	19454	50	NFIA,TRPS1,SOX5
5.392e-03	-5.22	Clusterin-like	interpro domains	IPR000753	2	1	18521	50	CLU
5.392e-03	-5.22	Glyco_hydro_79	interpro domains	IPR005199	2	1	18521	50	HPSE2
5.392e-03	-5.22	Gln_synt_N	interpro domains	IPR008147	2	1	18521	50	GLUL
5.392e-03	-5.22	Clusterin_C	interpro domains	IPR016015	2	1	18521	50	CLU
5.392e-03	-5.22	Gln_synt_N_sf	interpro domains	IPR036651	2	1	18521	50	GLUL
5.392e-03	-5.22	MSI_RRM2	interpro domains	IPR034126	2	1	18521	50	MSI2
5.392e-03	-5.22	Par3/HAL_N	interpro domains	IPR021922	2	1	18521	50	PARD3
5.392e-03	-5.22	ZNRF-3_ecto	interpro domains	IPR040700	2	1	18521	50	ZNRF3
5.392e-03	-5.22	Distrobrevin	interpro domains	IPR017432	2	1	18521	50	DTNA
5.392e-03	-5.22	Gln_synth_cat_dom	interpro domains	IPR008146	2	1	18521	50	GLUL
5.392e-03	-5.22	C2_Dock-B	interpro domains	IPR037811	2	1	18521	50	DOCK4
5.392e-03	-5.22	Clusterin_N	interpro domains	IPR016014	2	1	18521	50	CLU
5.394e-03	-5.22	left_upper_lobe	COSMIC cancer mutations	left_upper_lobe	558	6	16828	49	CTNND2,FBXL7,SLC4A4,RYR3,ERBB4,TRPS1
5.422e-03	-5.22	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-acute_lymphoblastic_leukaemia	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-acute_lymphoblastic_leukaemia	2081	13	16828	49	NFIA,SLC4A4,TNIK,DTNA,FGFR3,ERBB4,SOX5,ATP1A2,TRPS1,PREX2,CAMK2G,DAAM2,SLC25A18
5.432e-03	-5.22	Ig_I-set	interpro domains	IPR013098	132	3	18521	50	LSAMP,NTM,FGFR3
5.440e-03	-5.21	sarcoplasmic reticulum membrane	cellular component	GO:0033017	43	2	19108	49	RYR3,CAMK2G
5.443e-03	-5.21	Transmission across Chemical Synapses	REACTOME pathways	R-HSA-112315	217	4	10285	34	CAMK2G,SLC1A3,SLC1A2,GLUL
5.461e-03	-5.21	axon ensheathment	biological process	GO:0008366	130	3	18204	50	PARD3,CLU,QKI
5.461e-03	-5.21	ensheathment of neurons	biological process	GO:0007272	130	3	18204	50	PARD3,QKI,CLU
5.461e-03	-5.21	central_nervous_system-brainstem-glioma-astrocytoma_Grade_I	COSMIC cancer mutations	central_nervous_system-brainstem-glioma-astrocytoma_Grade_I	38	2	16828	49	QKI,FGFR3
5.486e-03	-5.21	regulation of elastin catabolic process	biological process	GO:0060310	2	1	18204	50	CST3
5.486e-03	-5.21	negative regulation of ERBB4 signaling pathway	biological process	GO:0120154	2	1	18204	50	CADM1
5.486e-03	-5.21	negative regulation of 3'-UTR-mediated mRNA stabilization	biological process	GO:1905869	2	1	18204	50	QKI
5.486e-03	-5.21	glutamine biosynthetic process	biological process	GO:0006542	2	1	18204	50	GLUL
5.486e-03	-5.21	regulation of neurofibrillary tangle assembly	biological process	GO:1902996	2	1	18204	50	CLU
5.486e-03	-5.21	myofibroblast contraction	biological process	GO:1990764	2	1	18204	50	QKI
5.486e-03	-5.21	Wnt receptor catabolic process	biological process	GO:0038018	2	1	18204	50	ZNRF3
5.486e-03	-5.21	negative regulation of blood vessel remodeling	biological process	GO:0060313	2	1	18204	50	CST3
5.486e-03	-5.21	fibroblast growth factor receptor apoptotic signaling pathway	biological process	GO:1902178	2	1	18204	50	FGFR3
5.486e-03	-5.21	establishment of planar polarity involved in nephron morphogenesis	biological process	GO:0072046	2	1	18204	50	ERBB4
5.492e-03	-5.20	organic anion transmembrane transporter activity	molecular function	GO:0008514	268	4	18094	48	SLC25A18,SLC1A3,SLC1A2,SLC4A4
5.535e-03	-5.20	salivary_gland-parotid-carcinoma-adenoid_cystic_carcinoma	COSMIC cancer mutations	salivary_gland-parotid-carcinoma-adenoid_cystic_carcinoma	561	6	16828	49	CAMK2G,TNIK,MAML2,RYR3,FGFR3,ERBB4
5.545e-03	-5.19	neutral L-amino acid transmembrane transporter activity	molecular function	GO:0015175	42	2	18094	48	SLC1A3,SLC1A2
5.578e-03	-5.19	carboxylic acid transmembrane transport	biological process	GO:1905039	131	3	18204	50	SLC1A2,SLC25A18,SLC1A3
5.612e-03	-5.18	Glyco_hydro_79n	pfam domains	PF03662	2	1	17795	50	HPSE2
5.612e-03	-5.18	Gln-synt_C	pfam domains	PF00120	2	1	17795	50	GLUL
5.612e-03	-5.18	Clusterin	pfam domains	PF01093	2	1	17795	50	CLU
5.612e-03	-5.18	Par3_HAL_N_term	pfam domains	PF12053	2	1	17795	50	PARD3
5.612e-03	-5.18	ZNRF_3_ecto	pfam domains	PF18212	2	1	17795	50	ZNRF3
5.612e-03	-5.18	calcium ion transmembrane transporter activity	molecular function	GO:0015085	136	3	18094	48	GPM6A,TRPM3,RYR3
5.696e-03	-5.17	SNTB2 (syntrophin beta 2)	protein interactions	6645	141	3	19454	50	ERBB4,FGFR3,DTNA
5.697e-03	-5.17	amino acid transport	biological process	GO:0006865	132	3	18204	50	SLC1A2,SLC1A3,SLC25A18
5.717e-03	-5.16	SH2D1A (SH2 domain containing 1A)	protein interactions	4068	44	2	19454	50	ERBB4,CAMK2G
5.755e-03	-5.16	kidney-carcinoma-clear_cell_renal_cell_carcinoma	COSMIC cancer mutations	kidney-carcinoma-clear_cell_renal_cell_carcinoma	13924	47	16828	49	DOCK4,CDH20,CLU,AHCYL2,HPSE2,ERBB4,QKI,SLC25A18,DAAM2,SASH1,TRPM3,NFIA,PITPNC1,GPC5,COL5A3,ATP1A2,ATP13A4,SOX5,PREX2,MAML2,FBXL7,GPM6A,TNIK,GLUL,PTGDS,SLC1A2,SLC4A4,TRPS1,ZNRF3,LSAMP,ABLIM1,CTNND2,DTNA,NKAIN3,PARD3,NDRG2,NHSL1,SLC1A3,NPAS3,FGFR3,MSI2,TPD52L1,RYR3,ZBTB20,CADM1,CAMK2G,RORA
5.755e-03	-5.16	clear_cell_renal_cell_carcinoma	COSMIC cancer mutations	clear_cell_renal_cell_carcinoma	13924	47	16828	49	FGFR3,NPAS3,NDRG2,NHSL1,SLC1A3,PARD3,DTNA,NKAIN3,RORA,CAMK2G,CADM1,ZBTB20,RYR3,TPD52L1,MSI2,SLC4A4,SLC1A2,GLUL,PTGDS,TNIK,CTNND2,LSAMP,ABLIM1,ZNRF3,TRPS1,COL5A3,GPC5,NFIA,PITPNC1,TRPM3,GPM6A,FBXL7,PREX2,MAML2,SOX5,ATP13A4,ATP1A2,CLU,CDH20,DOCK4,DAAM2,SLC25A18,SASH1,QKI,ERBB4,HPSE2,AHCYL2
5.767e-03	-5.16	sarcolemma	cellular component	GO:0042383	142	3	19108	49	RYR3,ATP1A2,DTNA
5.776e-03	-5.15	right_upper_lobe	COSMIC cancer mutations	right_upper_lobe	10376	39	16828	49	GPM6A,FBXL7,PREX2,ZBTB20,CADM1,RORA,ATP1A2,ATP13A4,RYR3,SOX5,NTM,GPC5,NPAS3,SLC1A3,NDRG2,COL5A3,FGFR3,TRPM3,DTNA,NKAIN3,PARD3,NFIA,PITPNC1,SLC25A18,SASH1,CTNND2,ABLIM1,LSAMP,HPSE2,TRPS1,AHCYL2,ZNRF3,ERBB4,CDH20,GLUL,DOCK4,TNIK,SLC4A4,SLC1A2
5.776e-03	-5.15	lung-right_upper_lobe-carcinoma-adenocarcinoma	COSMIC cancer mutations	lung-right_upper_lobe-carcinoma-adenocarcinoma	10376	39	16828	49	GLUL,CDH20,TNIK,DOCK4,SLC4A4,SLC1A2,SASH1,SLC25A18,CTNND2,LSAMP,ABLIM1,HPSE2,TRPS1,AHCYL2,ZNRF3,ERBB4,GPC5,NPAS3,SLC1A3,NDRG2,COL5A3,FGFR3,TRPM3,NKAIN3,DTNA,PARD3,PITPNC1,NFIA,GPM6A,FBXL7,ZBTB20,CADM1,PREX2,RORA,ATP1A2,ATP13A4,RYR3,SOX5,NTM
5.929e-03	-5.13	postsynapse	cellular component	GO:0098794	646	6	19108	49	CADM1,ATP1A2,GPM6A,CTNND2,ERBB4,TNIK
5.935e-03	-5.13	Vinculin, Vh2 four-helix bundle	gene3d domains	1.20.120.810	2	1	14470	43	CTNNA2
5.935e-03	-5.13	Glutamine synthetase, N-terminal domain	gene3d domains	3.10.20.70	2	1	14470	43	GLUL
5.935e-03	-5.13	-	gene3d domains	6.20.350.10	2	1	14470	43	RYR3
5.981e-03	-5.12	regulation of canonical Wnt signaling pathway	biological process	GO:0060828	265	4	18204	50	DAAM2,GPC5,ZNRF3,CTNND2
6.001e-03	-5.12	YWHAH (tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein eta)	protein interactions	7533	1083	8	19454	50	CAMK2G,SASH1,ABLIM1,PARD3,PITPNC1,NHSL1,TPD52L1,DOCK4
6.037e-03	-5.11	Calml3 (calmodulin-like 3)	protein interactions	70405	144	3	19454	50	ZBTB20,ABLIM1,CAMK2G
6.062e-03	-5.11	organic acid transmembrane transport	biological process	GO:1903825	135	3	18204	50	SLC25A18,SLC1A3,SLC1A2
6.064e-03	-5.11	I-set	pfam domains	PF07679	132	3	17795	50	FGFR3,LSAMP,NTM
6.107e-03	-5.10	axon	cellular component	GO:0030424	650	6	19108	49	NDRG2,PARD3,GPM6A,CTNNA2,SLC1A2,DTNA
6.161e-03	-5.09	cell development	biological process	GO:0048468	2236	13	18204	50	CLU,TNIK,ERBB4,GPM6A,CTNNA2,CTNND2,QKI,SLC1A3,PREX2,RORA,NTM,MSI2,PARD3
6.168e-03	-5.09	ATPASE_E1_E2	prosite domains	PS00154	36	2	12186	40	ATP13A4,ATP1A2
6.233e-03	-5.08	Glutamatergic synapse	KEGG pathways	ko04724	114	3	7161	24	SLC1A2,SLC1A3,GLUL
6.233e-03	-5.08	Glutamatergic synapse	KEGG pathways	hsa04724	114	3	7161	24	SLC1A3,SLC1A2,GLUL
6.237e-03	-5.08	intracellular monoatomic cation homeostasis	biological process	GO:0030003	428	5	18204	50	ATP13A4,SLC4A4,SLC1A3,RYR3,ATP1A2
6.288e-03	-5.07	basal plasma membrane	cellular component	GO:0009925	288	4	19108	49	ERBB4,SLC4A4,SLC1A3,CADM1
6.384e-03	-5.05	parotid	COSMIC cancer mutations	parotid	578	6	16828	49	RYR3,FGFR3,ERBB4,CAMK2G,TNIK,MAML2
6.391e-03	-5.05	MOB4 (MOB family member 4, phocein)	protein interactions	25843	147	3	19454	50	CAMK2G,ABLIM1,TNIK
6.402e-03	-5.05	skin-extremity-malignant_melanoma	COSMIC cancer mutations	skin-extremity-malignant_melanoma	1875	12	16828	49	COL5A3,PITPNC1,PARD3,DOCK4,CDH20,PREX2,FBXL7,SASH1,ERBB4,RYR3,ATP13A4,HPSE2
6.466e-03	-5.04	carboxylic acid biosynthetic process	biological process	GO:0046394	271	4	18204	50	SLC1A3,GLUL,QKI,PTGDS
6.554e-03	-5.03	GS_BETA_GRASP	prosite domains	PS51986	2	1	12186	40	GLUL
6.554e-03	-5.03	GS_CATALYTIC	prosite domains	PS51987	2	1	12186	40	GLUL
6.634e-03	-5.02	GSE1 (Gse1 coiled-coil protein)	protein interactions	23199	149	3	19454	50	NFIA,TNIK,SOX5
6.645e-03	-5.01	GABA shunt	BIOCYC pathways	HUMAN_GLUDEG-I-PWY	3	1	902	2	GLUL
6.646e-03	-5.01	skin-trunk-malignant_melanoma	COSMIC cancer mutations	skin-trunk-malignant_melanoma	2647	15	16828	49	SASH1,PREX2,MAML2,CTNND2,LSAMP,TRPS1,HPSE2,ATP1A2,ATP13A4,RYR3,SOX5,ERBB4,SLC1A3,CDH20,PARD3
6.702e-03	-5.01	neurotransmitter transport	biological process	GO:0006836	140	3	18204	50	SLC1A2,SLC1A3,ATP1A2
6.719e-03	-5.00	organic acid biosynthetic process	biological process	GO:0016053	274	4	18204	50	SLC1A3,GLUL,QKI,PTGDS
6.798e-03	-4.99	intracellular monoatomic ion homeostasis	biological process	GO:0006873	437	5	18204	50	ATP13A4,SLC4A4,ATP1A2,RYR3,SLC1A3
6.804e-03	-4.99	gliogenesis	biological process	GO:0042063	275	4	18204	50	NFIA,PARD3,QKI,CLU
6.841e-03	-4.98	face	COSMIC cancer mutations	face	2139	13	16828	49	FGFR3,GPC5,PARD3,TRPM3,RORA,LSAMP,ABLIM1,PREX2,GPM6A,ERBB4,ZNRF3,TRPS1,MSI2
6.875e-03	-4.98	transmembrane transport	biological process	GO:0055085	1264	9	18204	50	GPM6A,SLC4A4,ATP13A4,SLC25A18,TRPM3,SLC1A2,SLC1A3,RYR3,ATP1A2
6.911e-03	-4.97	central_nervous_system-brain-glioma-astrocytoma_Grade_III	COSMIC cancer mutations	central_nervous_system-brain-glioma-astrocytoma_Grade_III	1419	10	16828	49	PARD3,RYR3,ERBB4,FGFR3,HPSE2,GPC5,DAAM2,TRPM3,MAML2,CADM1
6.969e-03	-4.97	monoatomic anion transmembrane transport	biological process	GO:0098656	142	3	18204	50	SLC1A3,SLC1A2,SLC4A4
7.049e-03	-4.95	JADE3 (jade family PHD finger 3)	protein interactions	9767	49	2	19454	50	FGFR3,SASH1
7.064e-03	-4.95	SP7 (Sp7 transcription factor)	protein interactions	121340	297	4	19454	50	SOX5,TRPS1,NFIA,QKI
7.084e-03	-4.95	regulation of oligodendrocyte differentiation	biological process	GO:0048713	46	2	18204	50	DAAM2,QKI
7.135e-03	-4.94	SOX6 (SRY-box transcription factor 6)	protein interactions	55553	153	3	19454	50	NFIA,TRPS1,SOX5
7.144e-03	-4.94	secondary active transmembrane transporter activity	molecular function	GO:0015291	289	4	18094	48	SLC25A18,SLC4A4,SLC1A3,SLC1A2
7.191e-03	-4.93	cell morphogenesis involved in neuron differentiation	biological process	GO:0048667	443	5	18204	50	SLC1A3,PARD3,CTNNA2,PREX2,CTNND2
7.312e-03	-4.92	metal ion transport	biological process	GO:0030001	630	6	18204	50	TRPM3,SLC1A3,RYR3,ATP1A2,SLC4A4,GPM6A
7.364e-03	-4.91	soft_tissue-striated_muscle-rhabdomyosarcoma-alveolar	COSMIC cancer mutations	soft_tissue-striated_muscle-rhabdomyosarcoma-alveolar	2414	14	16828	49	NPAS3,NHSL1,SLC1A3,FGFR3,CDH20,TRPM3,PARD3,NFIA,CLU,SASH1,PREX2,TRPS1,ZNRF3,RYR3
7.364e-03	-4.91	alveolar	COSMIC cancer mutations	alveolar	2414	14	16828	49	SASH1,PREX2,RYR3,ZNRF3,TRPS1,FGFR3,NPAS3,NHSL1,SLC1A3,PARD3,CLU,NFIA,TRPM3,CDH20
7.396e-03	-4.91	CLb	smart domains	SM00030	2	1	9717	36	CLU
7.396e-03	-4.91	Gln-synt_C	smart domains	SM01230	2	1	9717	36	GLUL
7.396e-03	-4.91	CLa	smart domains	SM00035	2	1	9717	36	CLU
7.404e-03	-4.91	large_intestine-adenoma	COSMIC cancer mutations	large_intestine-adenoma	266	4	16828	49	SASH1,CDH20,SOX5,RYR3
7.493e-03	-4.89	cell surface	cellular component	GO:0009986	896	7	19108	49	SLC4A4,ATP1A2,GPC5,SLC1A3,SLC1A2,CLU,FGFR3
7.521e-03	-4.89	adult behavior	biological process	GO:0030534	146	3	18204	50	PREX2,SLC1A2,ATP1A2
7.521e-03	-4.89	mitotic cell cycle phase transition	biological process	GO:0044772	146	3	18204	50	NFIA,TPD52L1,FBXL7
7.592e-03	-4.88	third_ventricle	COSMIC cancer mutations	third_ventricle	45	2	16828	49	QKI,FGFR3
7.631e-03	-4.88	human chr8q23.3	chromosome location	human chr8q23.3	4	1	26134	50	TRPS1
7.657e-03	-4.87	CARM1 (coactivator associated arginine methyltransferase 1)	protein interactions	10498	304	4	19454	50	RORA,CAMK2G,DTNA,QKI
7.691e-03	-4.87	Hk2 (hexokinase 2)	protein interactions	25059	3	1	19454	50	PTGDS
7.691e-03	-4.87	Lrrc7 (leucine rich repeat containing 7)	protein interactions	117284	3	1	19454	50	CAMK2G
7.691e-03	-4.87	NRG3 (neuregulin 3)	protein interactions	10718	3	1	19454	50	ERBB4
7.691e-03	-4.87	BCO1 (beta-carotene oxygenase 1)	protein interactions	53630	3	1	19454	50	ABLIM1
7.691e-03	-4.87	Lep (leptin)	protein interactions	16846	3	1	19454	50	CLU
7.691e-03	-4.87	QRFPR (pyroglutamylated RFamide peptide receptor)	protein interactions	84109	3	1	19454	50	NTM
7.700e-03	-4.87	cell junction assembly	biological process	GO:0034329	285	4	18204	50	PARD3,CDH20,ERBB4,GPM6A
7.762e-03	-4.86	anchoring junction	cellular component	GO:0070161	902	7	19108	49	CDH20,FGFR3,CTNNA2,CTNND2,ATP1A2,CADM1,PARD3
7.847e-03	-4.85	basal part of cell	cellular component	GO:0045178	307	4	19108	49	SLC4A4,SLC1A3,ERBB4,CADM1
7.898e-03	-4.84	Amyotrophic lateral sclerosis (ALS)	WikiPathways	WP2447	38	2	5310	19	CST3,SLC1A2
7.909e-03	-4.84	SNAP91 (synaptosome associated protein 91)	protein interactions	9892	52	2	19454	50	GPM6A,ERBB4
7.938e-03	-4.84	acid-ammonia (or amide) ligase activity	molecular function	GO:0016880	3	1	18094	48	GLUL
7.938e-03	-4.84	epidermal growth factor receptor activity	molecular function	GO:0005006	3	1	18094	48	ERBB4
7.938e-03	-4.84	prostaglandin-D synthase activity	molecular function	GO:0004667	3	1	18094	48	PTGDS
7.938e-03	-4.84	cysteine transmembrane transporter activity	molecular function	GO:0033229	3	1	18094	48	SLC1A2
7.938e-03	-4.84	adenosylhomocysteinase activity	molecular function	GO:0004013	3	1	18094	48	AHCYL2
7.938e-03	-4.84	hydrolase activity, acting on carbon-sulfur bonds	molecular function	GO:0046508	3	1	18094	48	AHCYL2
7.938e-03	-4.84	neuregulin receptor activity	molecular function	GO:0038131	3	1	18094	48	ERBB4
8.007e-03	-4.83	G2/M transition of mitotic cell cycle	biological process	GO:0000086	49	2	18204	50	FBXL7,TPD52L1
8.007e-03	-4.83	regulation of filopodium assembly	biological process	GO:0051489	49	2	18204	50	DAAM2,GPM6A
8.021e-03	-4.83	skin-neck-malignant_melanoma	COSMIC cancer mutations	skin-neck-malignant_melanoma	1223	9	16828	49	SASH1,GPC5,PREX2,CTNND2,COL5A3,TRPM3,ATP1A2,ATP13A4,ERBB4
8.065e-03	-4.82	SOX5 (SRY-box transcription factor 5)	protein interactions	6660	160	3	19454	50	SOX5,TRPS1,NFIA
8.078e-03	-4.82	Adenosylhomocysteinase-like	interpro domains	IPR000043	3	1	18521	50	AHCYL2
8.078e-03	-4.82	Myelin_PLP_CS	interpro domains	IPR018237	3	1	18521	50	GPM6A
8.078e-03	-4.82	Adenosylhomocyst_ase-like_sf	interpro domains	IPR042172	3	1	18521	50	AHCYL2
8.078e-03	-4.82	SPRY3_RyR	interpro domains	IPR035762	3	1	18521	50	RYR3
8.078e-03	-4.82	Ryanrecept_TM4-6	interpro domains	IPR009460	3	1	18521	50	RYR3
8.078e-03	-4.82	Ryanodine_rcpt	interpro domains	IPR003032	3	1	18521	50	RYR3
8.078e-03	-4.82	SPIDER	interpro domains	IPR021090	3	1	18521	50	SASH1
8.078e-03	-4.82	MAML1-3	interpro domains	IPR046369	3	1	18521	50	MAML2
8.078e-03	-4.82	Ado_hCys_hydrolase_NAD-bd	interpro domains	IPR015878	3	1	18521	50	AHCYL2
8.078e-03	-4.82	TM_ErbB1	interpro domains	IPR049328	3	1	18521	50	ERBB4
8.078e-03	-4.82	Ryan_recept	interpro domains	IPR013333	3	1	18521	50	RYR3
8.078e-03	-4.82	Myelin_PLP	interpro domains	IPR001614	3	1	18521	50	GPM6A
8.078e-03	-4.82	NR_DBD_ROR	interpro domains	IPR044101	3	1	18521	50	RORA
8.078e-03	-4.82	S-Ado-L-homoCys_hydrolase_CS	interpro domains	IPR020082	3	1	18521	50	AHCYL2
8.078e-03	-4.82	Vinculin_CS	interpro domains	IPR000633	3	1	18521	50	CTNNA2
8.078e-03	-4.82	SPRY1_RyR	interpro domains	IPR035761	3	1	18521	50	RYR3
8.078e-03	-4.82	Mastermind-like_N	interpro domains	IPR019082	3	1	18521	50	MAML2
8.078e-03	-4.82	ROR_rcpt	interpro domains	IPR003079	3	1	18521	50	RORA
8.078e-03	-4.82	MAML_N_sf	interpro domains	IPR046370	3	1	18521	50	MAML2
8.078e-03	-4.82	SPRY2_RyR	interpro domains	IPR035764	3	1	18521	50	RYR3
8.078e-03	-4.82	RYDR_Jsol	interpro domains	IPR048581	3	1	18521	50	RYR3
8.157e-03	-4.81	oesophagus-middle_third-carcinoma-squamous_cell_carcinoma	COSMIC cancer mutations	oesophagus-middle_third-carcinoma-squamous_cell_carcinoma	3531	18	16828	49	COL5A3,GPC5,NHSL1,PARD3,SLC4A4,TRPM3,TNIK,CTNND2,ABLIM1,SASH1,GPM6A,ZBTB20,PREX2,MAML2,RYR3,SOX5,HPSE2,ATP1A2
8.206e-03	-4.80	FOXF2 (forkhead box F2)	protein interactions	2295	53	2	19454	50	ZBTB20,AHCYL2
8.206e-03	-4.80	MAL2 (mal, T cell differentiation protein 2)	protein interactions	114569	53	2	19454	50	TPD52L1,PITPNC1
8.206e-03	-4.80	middle_third	COSMIC cancer mutations	middle_third	3533	18	16828	49	GPC5,NHSL1,COL5A3,TRPM3,TNIK,PARD3,SLC4A4,SASH1,GPM6A,ZBTB20,MAML2,PREX2,CTNND2,ABLIM1,HPSE2,ATP1A2,SOX5,RYR3
8.218e-03	-4.80	central nervous system morphogenesis	biological process	GO:0021551	3	1	18204	50	ERBB4
8.218e-03	-4.80	regulation of calcium:sodium antiporter activity	biological process	GO:1903279	3	1	18204	50	ATP1A2
8.218e-03	-4.80	immune complex clearance	biological process	GO:0002434	3	1	18204	50	CLU
8.218e-03	-4.80	negative regulation of vascular associated smooth muscle contraction	biological process	GO:1904694	3	1	18204	50	DOCK4
8.218e-03	-4.80	radial glia guided migration of Purkinje cell	biological process	GO:0021942	3	1	18204	50	CTNNA2
8.218e-03	-4.80	cysteine transport	biological process	GO:0042883	3	1	18204	50	SLC1A2
8.218e-03	-4.80	protein targeting to lysosome involved in chaperone-mediated autophagy	biological process	GO:0061740	3	1	18204	50	CLU
8.218e-03	-4.80	susceptibility to natural killer cell mediated cytotoxicity	biological process	GO:0042271	3	1	18204	50	CADM1
8.218e-03	-4.80	regulation of platelet-derived growth factor production	biological process	GO:0090361	3	1	18204	50	NDRG2
8.218e-03	-4.80	cysteine transmembrane transport	biological process	GO:1903712	3	1	18204	50	SLC1A2
8.327e-03	-4.79	cell surface receptor signaling pathway via JAK-STAT	biological process	GO:0007259	50	2	18204	50	ERBB4,FGFR3
8.406e-03	-4.78	RR_TM4-6	pfam domains	PF06459	3	1	17795	50	RYR3
8.406e-03	-4.78	Myelin_PLP	pfam domains	PF01275	3	1	17795	50	GPM6A
8.406e-03	-4.78	RYDR_Jsol	pfam domains	PF21119	3	1	17795	50	RYR3
8.406e-03	-4.78	MamL-1	pfam domains	PF09596	3	1	17795	50	MAML2
8.406e-03	-4.78	RyR	pfam domains	PF02026	3	1	17795	50	RYR3
8.406e-03	-4.78	AdoHcyase_NAD	pfam domains	PF00670	3	1	17795	50	AHCYL2
8.406e-03	-4.78	AdoHcyase	pfam domains	PF05221	3	1	17795	50	AHCYL2
8.406e-03	-4.78	TM_ErbB1	pfam domains	PF21314	3	1	17795	50	ERBB4
8.406e-03	-4.78	SLY	pfam domains	PF12485	3	1	17795	50	SASH1
8.436e-03	-4.78	protein binding	molecular function	GO:0005515	13983	44	18094	48	PTGDS,CTNNA2,SLC1A2,GLUL,SASH1,ABLIM1,AHCYL2,ATP1A2,COL5A3,PARD3,SOX5,CDH20,GPM6A,TNIK,QKI,SLC1A3,CAMK2G,NTM,MAML2,DTNA,SLC25A18,DAAM2,NFIA,TRPS1,RYR3,SLC4A4,HPSE2,TPD52L1,ZNRF3,FBXL7,PITPNC1,MSI2,DOCK4,NDRG2,CLU,CST3,CTNND2,NPAS3,GPC5,RORA,ERBB4,FGFR3,CADM1,LSAMP
8.507e-03	-4.77	SYNM (synemin)	protein interactions	23336	54	2	19454	50	DTNA,ERBB4
8.603e-03	-4.76	central_nervous_system-temporoparietal-glioma-astrocytoma_Grade_IV	COSMIC cancer mutations	central_nervous_system-temporoparietal-glioma-astrocytoma_Grade_IV	48	2	16828	49	RYR3,PARD3
8.613e-03	-4.75	thyroid-carcinoma	COSMIC cancer mutations	thyroid-carcinoma	4126	20	16828	49	CADM1,SASH1,LSAMP,CTNND2,ATP1A2,TRPS1,ERBB4,ZNRF3,RYR3,SOX5,ATP13A4,GPC5,FGFR3,COL5A3,DOCK4,DTNA,TNIK,TRPM3,NFIA,PARD3
8.693e-03	-4.75	cellular response to organic cyclic compound	biological process	GO:0071407	464	5	18204	50	RORA,ATP1A2,RYR3,SLC1A3,SLC1A2
8.711e-03	-4.74	skin-lentigo	COSMIC cancer mutations	skin-lentigo	3	1	16828	49	FGFR3
8.711e-03	-4.74	skin-face-lentigo	COSMIC cancer mutations	skin-face-lentigo	3	1	16828	49	FGFR3
8.711e-03	-4.74	urinary_tract-bladder-papilloma	COSMIC cancer mutations	urinary_tract-bladder-papilloma	3	1	16828	49	FGFR3
8.711e-03	-4.74	skin-trunk-lentigo	COSMIC cancer mutations	skin-trunk-lentigo	3	1	16828	49	FGFR3
8.711e-03	-4.74	skin-leg-lentigo	COSMIC cancer mutations	skin-leg-lentigo	3	1	16828	49	FGFR3
8.711e-03	-4.74	skin-leg-other-seborrhoeic_keratosis	COSMIC cancer mutations	skin-leg-other-seborrhoeic_keratosis	3	1	16828	49	FGFR3
8.711e-03	-4.74	skin-forearm-lentigo	COSMIC cancer mutations	skin-forearm-lentigo	3	1	16828	49	FGFR3
8.711e-03	-4.74	skin-trunk-other-seborrhoeic_keratosis	COSMIC cancer mutations	skin-trunk-other-seborrhoeic_keratosis	3	1	16828	49	FGFR3
8.711e-03	-4.74	lentigo	COSMIC cancer mutations	lentigo	3	1	16828	49	FGFR3
8.711e-03	-4.74	skin-hand-lentigo	COSMIC cancer mutations	skin-hand-lentigo	3	1	16828	49	FGFR3
8.712e-03	-4.74	ATPase-coupled monoatomic cation transmembrane transporter activity	molecular function	GO:0019829	53	2	18094	48	ATP13A4,ATP1A2
8.738e-03	-4.74	trunk	COSMIC cancer mutations	trunk	3554	18	16828	49	ERBB4,SOX5,RYR3,ATP13A4,ATP1A2,TRPS1,HPSE2,LSAMP,ABLIM1,CTNND2,PREX2,MAML2,SASH1,PARD3,CDH20,FGFR3,SLC1A3,NPAS3
8.761e-03	-4.74	postsynaptic density	cellular component	GO:0014069	317	4	19108	49	CADM1,CTNND2,ERBB4,TNIK
8.771e-03	-4.74	EGR2 (early growth response 2)	protein interactions	1959	165	3	19454	50	SOX5,TRPS1,NFIA
8.814e-03	-4.73	SYN1 (synapsin I)	protein interactions	6853	55	2	19454	50	GPM6A,CAMK2G
8.814e-03	-4.73	AMPH (amphiphysin)	protein interactions	273	55	2	19454	50	GLUL,GPM6A
8.836e-03	-4.73	skin-back-malignant_melanoma	COSMIC cancer mutations	skin-back-malignant_melanoma	280	4	16828	49	TNIK,PREX2,ATP1A2,ERBB4
8.889e-03	-4.72	-	gene3d domains	1.10.490.160	3	1	14470	43	RYR3
8.889e-03	-4.72	-	gene3d domains	6.10.250.970	3	1	14470	43	MAML2
8.889e-03	-4.72	-	gene3d domains	6.10.250.2510	3	1	14470	43	CTNNA2
8.889e-03	-4.72	Adenosylhomocysteinase-like	gene3d domains	3.40.50.1480	3	1	14470	43	AHCYL2
8.972e-03	-4.71	chest	COSMIC cancer mutations	chest	147	3	16828	49	ERBB4,FGFR3,PREX2
8.982e-03	-4.71	regulation of nucleotide catabolic process	biological process	GO:0030811	52	2	18204	50	ZBTB20,SLC4A4
8.982e-03	-4.71	regulation of glycolytic process	biological process	GO:0006110	52	2	18204	50	ZBTB20,SLC4A4
8.982e-03	-4.71	regulation of purine nucleotide catabolic process	biological process	GO:0033121	52	2	18204	50	SLC4A4,ZBTB20
9.142e-03	-4.69	cervix-carcinoma-squamous_cell_carcinoma	COSMIC cancer mutations	cervix-carcinoma-squamous_cell_carcinoma	11789	42	16828	49	SLC1A2,SLC4A4,TNIK,DOCK4,GLUL,CDH20,LSAMP,ABLIM1,CTNND2,SASH1,DAAM2,SLC25A18,ERBB4,QKI,ZNRF3,CST3,TRPS1,HPSE2,FGFR3,COL5A3,SLC1A3,NHSL1,NPAS3,GPC5,PITPNC1,NFIA,PARD3,DTNA,TRPM3,RORA,ZBTB20,CADM1,MAML2,PREX2,FBXL7,GPM6A,NTM,TPD52L1,SOX5,RYR3,ATP13A4,ATP1A2
9.147e-03	-4.69	presynaptic membrane	cellular component	GO:0042734	168	3	19108	49	GPM6A,SLC1A2,ERBB4
9.157e-03	-4.69	PGNDSYNTHASE	prints domains	PR01254	3	1	5227	16	PTGDS
9.157e-03	-4.69	RORNUCRECPTR	prints domains	PR01293	3	1	5227	16	RORA
9.157e-03	-4.69	RYANODINER	prints domains	PR00795	3	1	5227	16	RYR3
9.157e-03	-4.69	MYELINPLP	prints domains	PR00214	3	1	5227	16	GPM6A
9.206e-03	-4.69	rhabdomyosarcoma	COSMIC cancer mutations	rhabdomyosarcoma	4150	20	16828	49	CTNND2,RORA,CAMK2G,SASH1,MAML2,PREX2,ZNRF3,RYR3,TRPS1,COL5A3,FGFR3,NPAS3,SLC1A3,NHSL1,PARD3,NFIA,CLU,CDH20,TRPM3,DOCK4
9.227e-03	-4.69	cervix	COSMIC cancer mutations	cervix	11793	42	16828	49	DOCK4,TNIK,GLUL,CDH20,SLC1A2,SLC4A4,SLC25A18,DAAM2,SASH1,ABLIM1,LSAMP,CTNND2,HPSE2,TRPS1,CST3,ERBB4,ZNRF3,QKI,SLC1A3,NHSL1,NPAS3,GPC5,FGFR3,COL5A3,DTNA,TRPM3,NFIA,PITPNC1,PARD3,PREX2,MAML2,ZBTB20,CADM1,FBXL7,GPM6A,RORA,ATP1A2,TPD52L1,NTM,ATP13A4,RYR3,SOX5
9.318e-03	-4.68	EGFR (epidermal growth factor receptor)	protein interactions	1956	3105	15	19454	50	ERBB4,DOCK4,GLUL,TRPS1,CTNND2,PTGDS,CLU,TNIK,PARD3,TRPM3,ABLIM1,CTNNA2,DTNA,AHCYL2,CAMK2G
9.318e-03	-4.68	neutral amino acid transport	biological process	GO:0015804	53	2	18204	50	SLC1A2,SLC1A3
9.318e-03	-4.68	regulation of chondrocyte differentiation	biological process	GO:0032330	53	2	18204	50	TRPS1,SOX5
9.395e-03	-4.67	positive regulation of kinase activity	biological process	GO:0033674	302	4	18204	50	SASH1,ERBB4,FGFR3,TPD52L1
9.399e-03	-4.67	positive regulation of MAPK cascade	biological process	GO:0043410	473	5	18204	50	SASH1,TPD52L1,FGFR3,ERBB4,TNIK
9.492e-03	-4.66	cell cycle phase transition	biological process	GO:0044770	159	3	18204	50	NFIA,TPD52L1,FBXL7
9.492e-03	-4.66	monoatomic anion transport	biological process	GO:0006820	159	3	18204	50	SLC1A3,SLC4A4,SLC1A2
9.659e-03	-4.64	cell cycle G2/M phase transition	biological process	GO:0044839	54	2	18204	50	FBXL7,TPD52L1
9.659e-03	-4.64	cell surface receptor signaling pathway via STAT	biological process	GO:0097696	54	2	18204	50	ERBB4,FGFR3
9.685e-03	-4.64	regulation of MAPK cascade	biological process	GO:0043408	669	6	18204	50	SASH1,NDRG2,FGFR3,TPD52L1,TNIK,ERBB4
9.709e-03	-4.63	HNRNPL (heterogeneous nuclear ribonucleoprotein L)	protein interactions	3191	1958	11	19454	50	FGFR3,DOCK4,ZBTB20,QKI,TRPS1,NFIA,PARD3,MSI2,ABLIM1,DTNA,AHCYL2
9.763e-03	-4.63	CILK1 (ciliogenesis associated kinase 1)	protein interactions	22858	58	2	19454	50	MSI2,CAMK2G
9.763e-03	-4.63	HOXB6 (homeobox B6)	protein interactions	3216	58	2	19454	50	AHCYL2,GLUL
9.816e-03	-4.62	ADOHCYASE_2	prosite domains	PS00739	3	1	12186	40	AHCYL2
9.816e-03	-4.62	VINCULIN_1	prosite domains	PS00663	3	1	12186	40	CTNNA2
9.816e-03	-4.62	MYELIN_PLP_1	prosite domains	PS00575	3	1	12186	40	GPM6A
9.816e-03	-4.62	MYELIN_PLP_2	prosite domains	PS01004	3	1	12186	40	GPM6A
9.816e-03	-4.62	ADOHCYASE_1	prosite domains	PS00738	3	1	12186	40	AHCYL2
1.001e-02	-4.60	response to cocaine	biological process	GO:0042220	55	2	18204	50	SLC1A3,SLC1A2
1.002e-02	-4.60	Znf_NHR/GATA	interpro domains	IPR013088	56	2	18521	50	RORA,TRPS1
1.009e-02	-4.60	ADAM17 (ADAM metallopeptidase domain 17)	protein interactions	6868	59	2	19454	50	CAMK2G,ERBB4
1.022e-02	-4.58	extrinsic component of membrane	cellular component	GO:0019898	175	3	19108	49	DTNA,CTNNA2,CDH20
1.022e-02	-4.58	internode region of axon	cellular component	GO:0033269	4	1	19108	49	PARD3
1.022e-02	-4.58	collagen type V trimer	cellular component	GO:0005588	4	1	19108	49	COL5A3
1.024e-02	-4.58	CCDC126 (coiled-coil domain containing 126)	protein interactions	90693	4	1	19454	50	GPM6A
1.024e-02	-4.58	Ctbp2 (C-terminal binding protein 2)	protein interactions	13017	4	1	19454	50	TRPS1
1.024e-02	-4.58	Tpd52 (tumor protein D52)	protein interactions	21985	4	1	19454	50	TPD52L1
1.024e-02	-4.58	Nme2 (NME/NM23 nucleoside diphosphate kinase 2)	protein interactions	18103	4	1	19454	50	RORA
1.024e-02	-4.58	CALML4 (calmodulin like 4)	protein interactions	91860	4	1	19454	50	CAMK2G
1.029e-02	-4.58	LHX3 (LIM homeobox 3)	protein interactions	8022	175	3	19454	50	NFIA,TRPS1,SOX5
1.036e-02	-4.57	asymmetric synapse	cellular component	GO:0032279	333	4	19108	49	CTNND2,ERBB4,TNIK,CADM1
1.042e-02	-4.56	SNTB1 (syntrophin beta 1)	protein interactions	6641	60	2	19454	50	DTNA,FGFR3
1.042e-02	-4.56	ITGA8 (integrin subunit alpha 8)	protein interactions	8516	60	2	19454	50	ZNRF3,CLU
1.049e-02	-4.56	import across plasma membrane	biological process	GO:0098739	165	3	18204	50	SLC1A2,SLC1A3,ATP1A2
1.057e-02	-4.55	ryanodine-sensitive calcium-release channel activity	molecular function	GO:0005219	4	1	18094	48	RYR3
1.061e-02	-4.55	GATA3 (GATA binding protein 3)	protein interactions	2625	177	3	19454	50	TRPS1,NFIA,QKI
1.061e-02	-4.55	SYNPO (synaptopodin)	protein interactions	11346	177	3	19454	50	ZBTB20,ABLIM1,CAMK2G
1.072e-02	-4.54	visual behavior	biological process	GO:0007632	57	2	18204	50	SLC1A2,ATP1A2
1.076e-02	-4.53	Ca/CaM-dep_prot_kinase-assoc	interpro domains	IPR013543	4	1	18521	50	CAMK2G
1.076e-02	-4.53	P5A-ATPase_N	interpro domains	IPR047819	4	1	18521	50	ATP13A4
1.076e-02	-4.53	TRPM_tetra_sf	interpro domains	IPR037162	4	1	18521	50	TRPM3
1.076e-02	-4.53	CTF/NFI_DNA-bd_CS	interpro domains	IPR019739	4	1	18521	50	NFIA
1.076e-02	-4.53	CTF/NFI	interpro domains	IPR000647	4	1	18521	50	NFIA
1.076e-02	-4.53	NHS-like	interpro domains	IPR024845	4	1	18521	50	NHSL1
1.076e-02	-4.53	Na/K-Atpase_Interacting	interpro domains	IPR008516	4	1	18521	50	NKAIN3
1.076e-02	-4.53	FGF_rcpt_fam	interpro domains	IPR016248	4	1	18521	50	FGFR3
1.076e-02	-4.53	P5B-type_ATPase	interpro domains	IPR047821	4	1	18521	50	ATP13A4
1.076e-02	-4.53	CTF/NFI_DNA-bd-dom	interpro domains	IPR020604	4	1	18521	50	NFIA
1.076e-02	-4.53	NDRG	interpro domains	IPR004142	4	1	18521	50	NDRG2
1.076e-02	-4.53	TPD52	interpro domains	IPR007327	4	1	18521	50	TPD52L1
1.076e-02	-4.53	CTF/NFI_DNA-bd_N	interpro domains	IPR019548	4	1	18521	50	NFIA
1.076e-02	-4.53	AbLIM_anchor	interpro domains	IPR032402	4	1	18521	50	ABLIM1
1.076e-02	-4.53	TRPM_tetra	interpro domains	IPR032415	4	1	18521	50	TRPM3
1.076e-02	-4.53	Tyr_kinase_EGF/ERB/XmrK_rcpt	interpro domains	IPR016245	4	1	18521	50	ERBB4
1.076e-02	-4.53	Alpha_catenin	interpro domains	IPR001033	4	1	18521	50	CTNNA2
1.078e-02	-4.53	nodular	COSMIC cancer mutations	nodular	1515	10	16828	49	SLC4A4,ATP13A4,ERBB4,CDH20,ATP1A2,CTNND2,ABLIM1,FGFR3,NPAS3,PREX2
1.085e-02	-4.52	kidney-other-neoplasm	COSMIC cancer mutations	kidney-other-neoplasm	10653	39	16828	49	TNIK,CDH20,GLUL,SLC1A2,CLU,AHCYL2,TRPS1,HPSE2,ERBB4,QKI,DAAM2,SLC25A18,SASH1,ABLIM1,LSAMP,CTNND2,DTNA,NKAIN3,TRPM3,PARD3,SLC1A3,NHSL1,NPAS3,GPC5,FGFR3,COL5A3,ATP1A2,TPD52L1,ATP13A4,SOX5,RYR3,MAML2,PREX2,ZBTB20,CADM1,CAMK2G,FBXL7,GPM6A,RORA
1.090e-02	-4.52	testis-germ_cell_tumour-seminoma	COSMIC cancer mutations	testis-germ_cell_tumour-seminoma	648	6	16828	49	FGFR3,PREX2,CAMK2G,ERBB4,TNIK,TRPS1
1.094e-02	-4.52	positive regulation of inclusion body assembly	biological process	GO:0090261	4	1	18204	50	CLU
1.094e-02	-4.52	response to glycoside	biological process	GO:1903416	4	1	18204	50	ATP1A2
1.094e-02	-4.52	negative regulation of germ cell proliferation	biological process	GO:1905937	4	1	18204	50	PTGDS
1.094e-02	-4.52	regulation of glutamate uptake involved in transmission of nerve impulse	biological process	GO:0051946	4	1	18204	50	ATP1A2
1.094e-02	-4.52	negative regulation of male germ cell proliferation	biological process	GO:2000255	4	1	18204	50	PTGDS
1.094e-02	-4.52	positive regulation of mesenchymal stem cell differentiation	biological process	GO:2000741	4	1	18204	50	SOX5
1.094e-02	-4.52	regulation of amino acid uptake involved in synaptic transmission	biological process	GO:0051941	4	1	18204	50	ATP1A2
1.094e-02	-4.52	cardiac muscle tissue regeneration	biological process	GO:0061026	4	1	18204	50	ERBB4
1.094e-02	-4.52	malate-aspartate shuttle	biological process	GO:0043490	4	1	18204	50	SLC25A18
1.094e-02	-4.52	regulation of collagen catabolic process	biological process	GO:0010710	4	1	18204	50	CST3
1.098e-02	-4.51	bone-tibia-Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour	COSMIC cancer mutations	bone-tibia-Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour	649	6	16828	49	QKI,TNIK,TRPM3,ABLIM1,FGFR3,PREX2
1.098e-02	-4.51	primitive_neuroectodermal_tumour-medulloblastoma	COSMIC cancer mutations	primitive_neuroectodermal_tumour-medulloblastoma	15350	49	16828	49	SLC1A2,SLC4A4,TNIK,PTGDS,GLUL,ABLIM1,LSAMP,CTNND2,ZNRF3,CST3,TRPS1,FGFR3,NDRG2,SLC1A3,NHSL1,NPAS3,PARD3,NKAIN3,DTNA,RORA,CADM1,ZBTB20,CAMK2G,NTM,TPD52L1,RYR3,MSI2,CLU,DOCK4,CDH20,SASH1,DAAM2,SLC25A18,ERBB4,QKI,AHCYL2,HPSE2,COL5A3,GPC5,PITPNC1,NFIA,TRPM3,PREX2,MAML2,FBXL7,GPM6A,ATP13A4,SOX5,ATP1A2
1.107e-02	-4.50	AdoHcyase_NAD	smart domains	SM00997	3	1	9717	36	AHCYL2
1.107e-02	-4.50	PLP	smart domains	SM00002	3	1	9717	36	GPM6A
1.107e-02	-4.50	MamL-1	smart domains	SM01275	3	1	9717	36	MAML2
1.107e-02	-4.50	AdoHcyase	smart domains	SM00996	3	1	9717	36	AHCYL2
1.110e-02	-4.50	ARHGAP29 (Rho GTPase activating protein 29)	protein interactions	9411	62	2	19454	50	PARD3,CAMK2G
1.110e-02	-4.50	cellular homeostasis	biological process	GO:0019725	689	6	18204	50	SLC4A4,ATP13A4,ZBTB20,SLC1A3,RYR3,ATP1A2
1.110e-02	-4.50	MYOD1 (myogenic differentiation 1)	protein interactions	4654	180	3	19454	50	NFIA,RORA,TRPS1
1.118e-02	-4.49	parietal_lobe	COSMIC cancer mutations	parietal_lobe	55	2	16828	49	FGFR3,QKI
1.119e-02	-4.49	TPD52	pfam domains	PF04201	4	1	17795	50	TPD52L1
1.119e-02	-4.49	TRPM_tetra	pfam domains	PF16519	4	1	17795	50	TRPM3
1.119e-02	-4.49	AbLIM_anchor	pfam domains	PF16182	4	1	17795	50	ABLIM1
1.119e-02	-4.49	CaMKII_AD	pfam domains	PF08332	4	1	17795	50	CAMK2G
1.119e-02	-4.49	NHS	pfam domains	PF15273	4	1	17795	50	NHSL1
1.119e-02	-4.49	NfI_DNAbd_pre-N	pfam domains	PF10524	4	1	17795	50	NFIA
1.119e-02	-4.49	P5-ATPase	pfam domains	PF12409	4	1	17795	50	ATP13A4
1.119e-02	-4.49	NKAIN	pfam domains	PF05640	4	1	17795	50	NKAIN3
1.119e-02	-4.49	CTF_NFI	pfam domains	PF00859	4	1	17795	50	NFIA
1.119e-02	-4.49	Ndr	pfam domains	PF03096	4	1	17795	50	NDRG2
1.128e-02	-4.48	Cardiac conduction	REACTOME pathways	R-HSA-5576891	142	3	10285	34	ATP1A2,CAMK2G,RYR3
1.134e-02	-4.48	IGc2	smart domains	SM00408	239	4	9717	36	LSAMP,CADM1,NTM,FGFR3
1.138e-02	-4.48	striated_muscle	COSMIC cancer mutations	striated_muscle	4228	20	16828	49	COL5A3,FGFR3,NPAS3,SLC1A3,NHSL1,PARD3,CLU,NFIA,TRPM3,CDH20,DOCK4,CTNND2,RORA,SASH1,CAMK2G,MAML2,PREX2,RYR3,ZNRF3,TRPS1
1.140e-02	-4.47	neuron projection development	biological process	GO:0031175	693	6	18204	50	PARD3,GPM6A,PREX2,TNIK,CTNNA2,CTNND2
1.143e-02	-4.47	human chr14q13.1	chromosome location	human chr14q13.1	6	1	26134	50	NPAS3
1.143e-02	-4.47	human chr4q34.2	chromosome location	human chr4q34.2	6	1	26134	50	GPM6A
1.145e-02	-4.47	YWHAG (tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein gamma)	protein interactions	7532	1211	8	19454	50	DOCK4,NHSL1,PITPNC1,PARD3,TPD52L1,ABLIM1,SASH1,CAMK2G
1.155e-02	-4.46	cellular response to endogenous stimulus	biological process	GO:0071495	1135	8	18204	50	NFIA,ERBB4,ATP1A2,RYR3,FGFR3,SLC1A3,SLC1A2,SOX5
1.160e-02	-4.46	skin-benign_melanocytic_nevus-junctional	COSMIC cancer mutations	skin-benign_melanocytic_nevus-junctional	4	1	16828	49	FGFR3
1.160e-02	-4.46	skin-lower_leg-malignant_melanoma-nodular	COSMIC cancer mutations	skin-lower_leg-malignant_melanoma-nodular	4	1	16828	49	PREX2
1.160e-02	-4.46	urinary_tract-bladder-other-normal	COSMIC cancer mutations	urinary_tract-bladder-other-normal	4	1	16828	49	FGFR3
1.160e-02	-4.46	inverted	COSMIC cancer mutations	inverted	4	1	16828	49	FGFR3
1.160e-02	-4.46	urinary_tract-bladder-papilloma-inverted	COSMIC cancer mutations	urinary_tract-bladder-papilloma-inverted	4	1	16828	49	FGFR3
1.160e-02	-4.46	skin-face-malignant_melanoma-superficial_spreading	COSMIC cancer mutations	skin-face-malignant_melanoma-superficial_spreading	4	1	16828	49	PREX2
1.169e-02	-4.45	postsynaptic specialization	cellular component	GO:0099572	345	4	19108	49	CADM1,TNIK,ERBB4,CTNND2
1.178e-02	-4.44	transmembrane receptor protein tyrosine kinase activity	molecular function	GO:0004714	62	2	18094	48	FGFR3,ERBB4
1.179e-02	-4.44	SYNC (syncoilin, intermediate filament protein)	protein interactions	81493	64	2	19454	50	MAML2,DTNA
1.179e-02	-4.44	VSX1 (visual system homeobox 1)	protein interactions	30813	64	2	19454	50	NFIA,TRPS1
1.182e-02	-4.44	regulation of smooth muscle contraction	biological process	GO:0006940	60	2	18204	50	DOCK4,ATP1A2
1.182e-02	-4.44	export across plasma membrane	biological process	GO:0140115	60	2	18204	50	SLC4A4,ATP1A2
1.184e-02	-4.44	TRPM, tetramerisation domain	gene3d domains	1.20.5.1010	4	1	14470	43	TRPM3
1.192e-02	-4.43	chemical homeostasis	biological process	GO:0048878	914	7	18204	50	RYR3,SLC1A3,ATP1A2,ZBTB20,RORA,SLC4A4,ATP13A4
1.192e-02	-4.43	cartilage development	biological process	GO:0051216	173	3	18204	50	SOX5,NFIA,FGFR3
1.200e-02	-4.42	Erythroid Transcription Factor GATA-1, subunit A	gene3d domains	3.30.50.10	56	2	14470	43	RORA,TRPS1
1.212e-02	-4.41	regulation of protein phosphorylation	biological process	GO:0001932	917	7	18204	50	PARD3,FGFR3,TPD52L1,CADM1,ERBB4,TNIK,SASH1
1.219e-02	-4.41	ALPHACATENIN	prints domains	PR00805	4	1	5227	16	CTNNA2
1.219e-02	-4.41	skin-arm-malignant_melanoma	COSMIC cancer mutations	skin-arm-malignant_melanoma	1308	9	16828	49	NTM,ERBB4,COL5A3,SLC4A4,ZBTB20,ATP1A2,TRPM3,TRPS1,NPAS3
1.220e-02	-4.41	regulation of vascular endothelial growth factor production	biological process	GO:0010574	61	2	18204	50	NDRG2,RORA
1.222e-02	-4.40	Neurotransmitter Release Cycle	REACTOME pathways	R-HSA-112310	51	2	10285	34	SLC1A3,SLC1A2
1.223e-02	-4.40	monoatomic cation homeostasis	biological process	GO:0055080	505	5	18204	50	SLC4A4,ATP13A4,ATP1A2,SLC1A3,RYR3
1.223e-02	-4.40	astrocytoma_Grade_III	COSMIC cancer mutations	astrocytoma_Grade_III	1544	10	16828	49	PARD3,RYR3,ERBB4,HPSE2,TRPM3,FGFR3,GPC5,DAAM2,MAML2,CADM1
1.230e-02	-4.40	KLF5 (KLF transcription factor 5)	protein interactions	688	187	3	19454	50	NFIA,TRPS1,CLU
1.240e-02	-4.39	cell migration	biological process	GO:0016477	921	7	18204	50	GPM6A,DOCK4,CDH20,DAAM2,CTNNA2,ERBB4,GPC5
1.248e-02	-4.38	HNF1B (HNF1 homeobox B)	protein interactions	6928	188	3	19454	50	NFIA,TRPS1,SOX5
1.249e-02	-4.38	adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains	biological process	GO:0002460	176	3	18204	50	CADM1,CLU,RORA
1.250e-02	-4.38	ORM1 (orosomucoid 1)	protein interactions	5004	66	2	19454	50	CLU,PTGDS
1.250e-02	-4.38	MAML1 (mastermind like transcriptional coactivator 1)	protein interactions	9794	66	2	19454	50	NFIA,MAML2
1.252e-02	-4.38	circulatory system process	biological process	GO:0003013	508	5	18204	50	SLC1A3,ATP1A2,SLC4A4,SLC1A2,DOCK4
1.259e-02	-4.38	regulation of carbohydrate catabolic process	biological process	GO:0043470	62	2	18204	50	SLC4A4,ZBTB20
1.261e-02	-4.37	CDH1 (cadherin 1)	protein interactions	999	757	6	19454	50	CTNND2,PARD3,NDRG2,CTNNA2,ABLIM1,NHSL1
1.262e-02	-4.37	bone-pelvis-chondrosarcoma	COSMIC cancer mutations	bone-pelvis-chondrosarcoma	311	4	16828	49	COL5A3,ERBB4,LSAMP,DAAM2
1.274e-02	-4.36	SH3_2	pfam domains	PF07653	61	2	17795	50	DOCK4,SASH1
1.276e-02	-4.36	calcium- and calmodulin-dependent protein kinase complex	cellular component	GO:0005954	5	1	19108	49	CAMK2G
1.276e-02	-4.36	neurofibrillary tangle	cellular component	GO:0097418	5	1	19108	49	CLU
1.279e-02	-4.36	TRPM6 (transient receptor potential cation channel subfamily M member 6)	protein interactions	140803	5	1	19454	50	TRPM3
1.279e-02	-4.36	NRG2 (neuregulin 2)	protein interactions	9542	5	1	19454	50	ERBB4
1.279e-02	-4.36	EPPIN (epididymal peptidase inhibitor)	protein interactions	57119	5	1	19454	50	CLU
1.279e-02	-4.36	CAMK2N2 (calcium/calmodulin dependent protein kinase II inhibitor 2)	protein interactions	94032	5	1	19454	50	CAMK2G
1.279e-02	-4.36	ARSI (arylsulfatase family member I)	protein interactions	340075	5	1	19454	50	AHCYL2
1.279e-02	-4.36	Hk3 (hexokinase 3)	protein interactions	25060	5	1	19454	50	PTGDS
1.279e-02	-4.36	ADCYAP1R1 (ADCYAP receptor type I)	protein interactions	117	5	1	19454	50	CLU
1.279e-02	-4.36	PTGER2 (prostaglandin E receptor 2)	protein interactions	5732	5	1	19454	50	PTGDS
1.302e-02	-4.34	pancreas-carcinoma	COSMIC cancer mutations	pancreas-carcinoma	14770	48	16828	49	FGFR3,NPAS3,NHSL1,NDRG2,SLC1A3,PARD3,NKAIN3,RORA,CAMK2G,CADM1,ZBTB20,RYR3,TPD52L1,NTM,MSI2,SLC4A4,SLC1A2,GLUL,PTGDS,TNIK,CTNND2,LSAMP,ABLIM1,ZNRF3,TRPS1,CST3,COL5A3,GPC5,NFIA,PITPNC1,TRPM3,FBXL7,GPM6A,MAML2,PREX2,ATP13A4,SOX5,ATP1A2,CLU,CDH20,DOCK4,SLC25A18,DAAM2,SASH1,QKI,ERBB4,HPSE2,AHCYL2
1.307e-02	-4.34	CTF_NFI_1	prosite domains	PS00349	4	1	12186	40	NFIA
1.307e-02	-4.34	CTF_NFI_2	prosite domains	PS51080	4	1	12186	40	NFIA
1.308e-02	-4.34	synapse organization	biological process	GO:0050808	333	4	18204	50	CTNND2,GPM6A,NFIA,ERBB4
1.313e-02	-4.33	response to endogenous stimulus	biological process	GO:0009719	1402	9	18204	50	NFIA,SLC1A2,SOX5,PTGDS,ERBB4,FGFR3,SLC1A3,RYR3,ATP1A2
1.317e-02	-4.33	carboxylic acid transmembrane transporter activity	molecular function	GO:0046943	186	3	18094	48	SLC1A2,SLC1A3,SLC25A18
1.318e-02	-4.33	main axon	cellular component	GO:0044304	68	2	19108	49	SLC1A2,PARD3
1.319e-02	-4.33	endoplasmic reticulum	cellular component	GO:0005783	2051	11	19108	49	ATP1A2,ATP13A4,CAMK2G,COL5A3,PTGDS,RYR3,AHCYL2,CST3,GLUL,CLU,FGFR3
1.320e-02	-4.33	fibroblast growth factor receptor activity	molecular function	GO:0005007	5	1	18094	48	FGFR3
1.321e-02	-4.33	lung-carcinoma-non_small_cell_carcinoma	COSMIC cancer mutations	lung-carcinoma-non_small_cell_carcinoma	5198	23	16828	49	MAML2,PREX2,CAMK2G,FBXL7,RORA,MSI2,SOX5,ATP13A4,SLC1A3,NPAS3,FGFR3,COL5A3,PITPNC1,PARD3,DAAM2,LSAMP,ABLIM1,CTNND2,TRPS1,ERBB4,QKI,TNIK,CLU
1.321e-02	-4.33	non_small_cell_carcinoma	COSMIC cancer mutations	non_small_cell_carcinoma	5198	23	16828	49	SOX5,ATP13A4,MSI2,RORA,FBXL7,CAMK2G,MAML2,PREX2,PARD3,PITPNC1,COL5A3,FGFR3,NPAS3,SLC1A3,QKI,ERBB4,TRPS1,CTNND2,LSAMP,ABLIM1,DAAM2,CLU,TNIK
1.322e-02	-4.33	monoatomic ion homeostasis	biological process	GO:0050801	515	5	18204	50	ATP1A2,RYR3,SLC1A3,SLC4A4,ATP13A4
1.332e-02	-4.32	human chr8q13.2	chromosome location	human chr8q13.2	7	1	26134	50	PREX2
1.336e-02	-4.32	organic acid transmembrane transporter activity	molecular function	GO:0005342	187	3	18094	48	SLC1A3,SLC1A2,SLC25A18
1.343e-02	-4.31	Na/HCO3_transpt	interpro domains	IPR003024	5	1	18521	50	SLC4A4
1.343e-02	-4.31	P-type_TPase_V	interpro domains	IPR006544	5	1	18521	50	ATP13A4
1.343e-02	-4.31	DOCK_N_sub1	interpro domains	IPR042455	5	1	18521	50	DOCK4
1.343e-02	-4.31	DOCK_N	interpro domains	IPR032376	5	1	18521	50	DOCK4
1.343e-02	-4.31	Vinculin/catenin	interpro domains	IPR006077	5	1	18521	50	CTNNA2
1.343e-02	-4.31	BBP-like	interpro domains	IPR045071	5	1	18521	50	QKI
1.343e-02	-4.31	PI_transfer	interpro domains	IPR001666	5	1	18521	50	PITPNC1
1.354e-02	-4.30	GRB2 (growth factor receptor bound protein 2)	protein interactions	2885	769	6	19454	50	DOCK4,FGFR3,CLU,ERBB4,SLC1A2,MSI2
1.363e-02	-4.30	temporoparietal	COSMIC cancer mutations	temporoparietal	61	2	16828	49	RYR3,PARD3
1.363e-02	-4.30	Heparan sulfate/heparin (HS-GAG) metabolism	REACTOME pathways	R-HSA-1638091	54	2	10285	34	GPC5,HPSE2
1.366e-02	-4.29	stem cell differentiation	biological process	GO:0048863	182	3	18204	50	GPM6A,MSI2,ERBB4
1.366e-02	-4.29	positive regulation of amyloid fibril formation	biological process	GO:1905908	5	1	18204	50	CLU
1.366e-02	-4.29	ERBB2-ERBB4 signaling pathway	biological process	GO:0038135	5	1	18204	50	ERBB4
1.366e-02	-4.29	central nervous system myelin maintenance	biological process	GO:0032286	5	1	18204	50	CLU
1.366e-02	-4.29	amygdala development	biological process	GO:0021764	5	1	18204	50	ATP1A2
1.367e-02	-4.29	neoplasm	COSMIC cancer mutations	neoplasm	14787	48	16828	49	FBXL7,GPM6A,MAML2,PREX2,ATP1A2,SOX5,ATP13A4,GPC5,COL5A3,TRPM3,NFIA,SASH1,DAAM2,SLC25A18,HPSE2,AHCYL2,QKI,ERBB4,CDH20,DOCK4,CLU,CAMK2G,ZBTB20,CADM1,RORA,MSI2,RYR3,NTM,TPD52L1,NPAS3,NDRG2,SLC1A3,NHSL1,FGFR3,NKAIN3,DTNA,PARD3,CTNND2,LSAMP,ABLIM1,CST3,TRPS1,ZNRF3,PTGDS,GLUL,TNIK,SLC4A4,SLC1A2
1.377e-02	-4.29	apoptotic mitochondrial changes	biological process	GO:0008637	65	2	18204	50	CLU,ERBB4
1.386e-02	-4.28	regulation of carbohydrate metabolic process	biological process	GO:0006109	183	3	18204	50	RORA,SLC4A4,ZBTB20
1.389e-02	-4.28	regulation of Wnt signaling pathway	biological process	GO:0030111	339	4	18204	50	CTNND2,GPC5,DAAM2,ZNRF3
1.391e-02	-4.28	brain development	biological process	GO:0007420	724	6	18204	50	RORA,ERBB4,ATP1A2,SLC1A2,CTNNA2,NDRG2
1.397e-02	-4.27	IP_trans	pfam domains	PF02121	5	1	17795	50	PITPNC1
1.397e-02	-4.27	Vinculin	pfam domains	PF01044	5	1	17795	50	CTNNA2
1.397e-02	-4.27	DOCK_N	pfam domains	PF16172	5	1	17795	50	DOCK4
1.399e-02	-4.27	MTMR9 (myotubularin related protein 9)	protein interactions	66036	70	2	19454	50	ERBB4,CLU
1.400e-02	-4.27	adenoma	COSMIC cancer mutations	adenoma	2873	15	16828	49	GPC5,NPAS3,COL5A3,FGFR3,TRPM3,CDH20,PARD3,SASH1,GPM6A,ZBTB20,CTNND2,HPSE2,RYR3,SOX5,ERBB4
1.406e-02	-4.26	superficial_spreading	COSMIC cancer mutations	superficial_spreading	1110	8	16828	49	PREX2,FGFR3,COL5A3,CTNND2,NTM,ERBB4,ATP13A4,SLC4A4
1.412e-02	-4.26	YES1 (YES proto-oncogene 1, Src family tyrosine kinase)	protein interactions	7525	364	4	19454	50	MSI2,ERBB4,GLUL,CAMK2G
1.412e-02	-4.26	neuron to neuron synapse	cellular component	GO:0098984	365	4	19108	49	CTNND2,TNIK,ERBB4,CADM1
1.413e-02	-4.26	lower_leg	COSMIC cancer mutations	lower_leg	174	3	16828	49	FGFR3,ERBB4,PREX2
1.418e-02	-4.26	positive regulation of tyrosine phosphorylation of STAT protein	biological process	GO:0042531	66	2	18204	50	ERBB4,FGFR3
1.420e-02	-4.25	Validated targets of C-MYC transcriptional repression	Pathway Interaction DB	myc_represspathway	61	2	2226	7	NDRG2,CLU
1.425e-02	-4.25	DNAJC5 (DnaJ heat shock protein family (Hsp40) member C5)	protein interactions	80331	365	4	19454	50	CLU,CADM1,PARD3,DTNA
1.433e-02	-4.25	NFIX (nuclear factor I X)	protein interactions	4784	198	3	19454	50	NFIA,TRPS1,SOX5
1.437e-02	-4.24	ANK2 (ankyrin 2)	protein interactions	287	71	2	19454	50	GPM6A,TNIK
1.437e-02	-4.24	UNKL (unk like zinc finger)	protein interactions	64718	71	2	19454	50	AHCYL2,QKI
1.446e-02	-4.24	Synaptic Vesicle Pathway	WikiPathways	WP2267	52	2	5310	19	ATP1A2,SLC1A3
1.448e-02	-4.24	skin-other-lichenoid_keratosis	COSMIC cancer mutations	skin-other-lichenoid_keratosis	5	1	16828	49	FGFR3
1.448e-02	-4.24	skin-lower_back-other-nevus_sebaceous	COSMIC cancer mutations	skin-lower_back-other-nevus_sebaceous	5	1	16828	49	FGFR3
1.448e-02	-4.24	syringocystadenoma_papilliferum	COSMIC cancer mutations	syringocystadenoma_papilliferum	5	1	16828	49	FGFR3
1.448e-02	-4.24	skin-lower_leg-other-lichenoid_keratosis	COSMIC cancer mutations	skin-lower_leg-other-lichenoid_keratosis	5	1	16828	49	FGFR3
1.448e-02	-4.24	skin-face-other-nevus_sebaceous	COSMIC cancer mutations	skin-face-other-nevus_sebaceous	5	1	16828	49	FGFR3
1.448e-02	-4.24	skin-face-other-lichenoid_keratosis	COSMIC cancer mutations	skin-face-other-lichenoid_keratosis	5	1	16828	49	FGFR3
1.448e-02	-4.24	skin-upper_arm-other-lichenoid_keratosis	COSMIC cancer mutations	skin-upper_arm-other-lichenoid_keratosis	5	1	16828	49	FGFR3
1.448e-02	-4.24	skin-hand-other-lichenoid_keratosis	COSMIC cancer mutations	skin-hand-other-lichenoid_keratosis	5	1	16828	49	FGFR3
1.448e-02	-4.24	skin-breast-other-lichenoid_keratosis	COSMIC cancer mutations	skin-breast-other-lichenoid_keratosis	5	1	16828	49	FGFR3
1.448e-02	-4.24	skin-flank-other-lichenoid_keratosis	COSMIC cancer mutations	skin-flank-other-lichenoid_keratosis	5	1	16828	49	FGFR3
1.448e-02	-4.24	skin-neck-other-lichenoid_keratosis	COSMIC cancer mutations	skin-neck-other-lichenoid_keratosis	5	1	16828	49	FGFR3
1.448e-02	-4.24	skin-upper_leg-other-lichenoid_keratosis	COSMIC cancer mutations	skin-upper_leg-other-lichenoid_keratosis	5	1	16828	49	FGFR3
1.448e-02	-4.24	skin-arm-other-seborrhoeic_keratosis	COSMIC cancer mutations	skin-arm-other-seborrhoeic_keratosis	5	1	16828	49	FGFR3
1.448e-02	-4.24	skin-ear-other-nevus_sebaceous	COSMIC cancer mutations	skin-ear-other-nevus_sebaceous	5	1	16828	49	FGFR3
1.448e-02	-4.24	lichenoid_keratosis	COSMIC cancer mutations	lichenoid_keratosis	5	1	16828	49	FGFR3
1.448e-02	-4.24	monoclonal_gammopathy_of_undetermined_significance	COSMIC cancer mutations	monoclonal_gammopathy_of_undetermined_significance	5	1	16828	49	FGFR3
1.448e-02	-4.24	skin-lower_leg-malignant_melanoma-superficial_spreading	COSMIC cancer mutations	skin-lower_leg-malignant_melanoma-superficial_spreading	5	1	16828	49	PREX2
1.448e-02	-4.24	skin-shoulder-other-lichenoid_keratosis	COSMIC cancer mutations	skin-shoulder-other-lichenoid_keratosis	5	1	16828	49	FGFR3
1.448e-02	-4.24	skin-chest-other-lichenoid_keratosis	COSMIC cancer mutations	skin-chest-other-lichenoid_keratosis	5	1	16828	49	FGFR3
1.448e-02	-4.24	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-monoclonal_gammopathy_of_undetermined_significance	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-monoclonal_gammopathy_of_undetermined_significance	5	1	16828	49	FGFR3
1.448e-02	-4.24	skin-forearm-other-lichenoid_keratosis	COSMIC cancer mutations	skin-forearm-other-lichenoid_keratosis	5	1	16828	49	FGFR3
1.448e-02	-4.24	skin-adnexal_tumour-syringocystadenoma_papilliferum	COSMIC cancer mutations	skin-adnexal_tumour-syringocystadenoma_papilliferum	5	1	16828	49	FGFR3
1.448e-02	-4.24	skin-upper_back-other-lichenoid_keratosis	COSMIC cancer mutations	skin-upper_back-other-lichenoid_keratosis	5	1	16828	49	FGFR3
1.448e-02	-4.24	skin-breast-other-nevus_sebaceous	COSMIC cancer mutations	skin-breast-other-nevus_sebaceous	5	1	16828	49	FGFR3
1.448e-02	-4.24	skin-forearm-other-seborrhoeic_keratosis	COSMIC cancer mutations	skin-forearm-other-seborrhoeic_keratosis	5	1	16828	49	FGFR3
1.448e-02	-4.24	skin-lower_back-other-lichenoid_keratosis	COSMIC cancer mutations	skin-lower_back-other-lichenoid_keratosis	5	1	16828	49	FGFR3
1.448e-02	-4.24	skin-scalp-other-nevus_sebaceous	COSMIC cancer mutations	skin-scalp-other-nevus_sebaceous	5	1	16828	49	FGFR3
1.448e-02	-4.24	skin-hip-other-seborrhoeic_keratosis	COSMIC cancer mutations	skin-hip-other-seborrhoeic_keratosis	5	1	16828	49	FGFR3
1.448e-02	-4.24	skin-shoulder-other-nevus_sebaceous	COSMIC cancer mutations	skin-shoulder-other-nevus_sebaceous	5	1	16828	49	FGFR3
1.448e-02	-4.24	skin-neck-other-nevus_sebaceous	COSMIC cancer mutations	skin-neck-other-nevus_sebaceous	5	1	16828	49	FGFR3
1.451e-02	-4.23	DDA1 (DET1 and DDB1 associated 1)	protein interactions	79016	367	4	19454	50	DOCK4,ZBTB20,NFIA,TRPS1
1.476e-02	-4.22	Ppp1cb (protein phosphatase 1 catalytic subunit beta)	protein interactions	19046	72	2	19454	50	ABLIM1,PARD3
1.476e-02	-4.22	DPYSL3 (dihydropyrimidinase like 3)	protein interactions	1809	72	2	19454	50	TNIK,GPM6A
1.477e-02	-4.22	Dedicator of cytokinesis N-terminal subdomain	gene3d domains	1.20.1270.350	5	1	14470	43	DOCK4
1.477e-02	-4.22	-	gene3d domains	6.10.140.620	5	1	14470	43	CAMK2G
1.477e-02	-4.22	Formin, FH3 diaphanous domain	gene3d domains	1.10.238.150	5	1	14470	43	DAAM2
1.500e-02	-4.20	adenoid_cystic_carcinoma	COSMIC cancer mutations	adenoid_cystic_carcinoma	1123	8	16828	49	TNIK,RYR3,ERBB4,CAMK2G,MAML2,CTNND2,RORA,FGFR3
1.501e-02	-4.20	regulation of vasoconstriction	biological process	GO:0019229	68	2	18204	50	DOCK4,ATP1A2
1.501e-02	-4.20	lung-carcinoid-endocrine_tumour	COSMIC cancer mutations	lung-carcinoid-endocrine_tumour	502	5	16828	49	TNIK,CAMK2G,SASH1,ERBB4,FGFR3
1.512e-02	-4.19	FEV (FEV transcription factor, ETS family member)	protein interactions	54738	202	3	19454	50	NFIA,SOX5,TRPS1
1.522e-02	-4.19	PITRANSFER	prints domains	PR00391	5	1	5227	16	PITPNC1
1.522e-02	-4.19	NAHCO3TRSPRT	prints domains	PR01232	5	1	5227	16	SLC4A4
1.526e-02	-4.18	positive regulation of multicellular organismal process	biological process	GO:0051240	1691	10	18204	50	ZBTB20,SOX5,SASH1,CLU,ERBB4,CADM1,QKI,ATP1A2,RORA,PARD3
1.529e-02	-4.18	PAR polarity complex	cellular component	GO:0120157	6	1	19108	49	PARD3
1.531e-02	-4.18	DPYSL2 (dihydropyrimidinase like 2)	protein interactions	1808	203	3	19454	50	TPD52L1,TNIK,GPM6A
1.532e-02	-4.18	SOX11 (SRY-box transcription factor 11)	protein interactions	6664	6	1	19454	50	SOX5
1.532e-02	-4.18	SLC12A5 (solute carrier family 12 member 5)	protein interactions	57468	6	1	19454	50	GPM6A
1.532e-02	-4.18	DRP2 (dystrophin related protein 2)	protein interactions	1821	6	1	19454	50	DTNA
1.532e-02	-4.18	FGF23 (fibroblast growth factor 23)	protein interactions	8074	6	1	19454	50	FGFR3
1.532e-02	-4.18	RSPO3 (R-spondin 3)	protein interactions	84870	6	1	19454	50	ZNRF3
1.532e-02	-4.18	SOX1 (SRY-box transcription factor 1)	protein interactions	6656	6	1	19454	50	SOX5
1.532e-02	-4.18	DAZ4 (deleted in azoospermia 4)	protein interactions	57135	6	1	19454	50	QKI
1.532e-02	-4.18	CYRIA (CYFIP related Rac1 interactor A)	protein interactions	81553	6	1	19454	50	GPM6A
1.532e-02	-4.18	Tiam2 (T cell lymphoma invasion and metastasis 2)	protein interactions	24001	6	1	19454	50	DTNA
1.532e-02	-4.18	PBP2 (Pbp2p)	protein interactions	852533	6	1	19454	50	QKI
1.532e-02	-4.18	NRG4 (neuregulin 4)	protein interactions	145957	6	1	19454	50	ERBB4
1.532e-02	-4.18	GPR135 (G protein-coupled receptor 135)	protein interactions	64582	6	1	19454	50	TPD52L1
1.532e-02	-4.18	CIBAR2 (CBY1 interacting BAR domain containing 2)	protein interactions	339145	6	1	19454	50	CAMK2G
1.532e-02	-4.18	FGF18 (fibroblast growth factor 18)	protein interactions	8817	6	1	19454	50	FGFR3
1.532e-02	-4.18	FGF6 (fibroblast growth factor 6)	protein interactions	2251	6	1	19454	50	FGFR3
1.532e-02	-4.18	TAT (tyrosine aminotransferase)	protein interactions	6898	6	1	19454	50	GLUL
1.532e-02	-4.18	CYP39A1 (cytochrome P450 family 39 subfamily A member 1)	protein interactions	51302	6	1	19454	50	GLUL
1.532e-02	-4.18	Taok2 (TAO kinase 2)	protein interactions	381921	6	1	19454	50	CLU
1.539e-02	-4.17	skin-ankle-malignant_melanoma-acral_lentiginous	COSMIC cancer mutations	skin-ankle-malignant_melanoma-acral_lentiginous	330	4	16828	49	PARD3,ATP13A4,ERBB4,PREX2
1.547e-02	-4.17	C20 prostanoid biosynthesis	BIOCYC pathways	META_PWY66-374	7	1	902	2	PTGDS
1.547e-02	-4.17	C20 prostanoid biosynthesis	BIOCYC pathways	HUMAN_PWY66-374	7	1	902	2	PTGDS
1.549e-02	-4.17	seminoma	COSMIC cancer mutations	seminoma	700	6	16828	49	TRPS1,CAMK2G,PREX2,TNIK,ERBB4,FGFR3
1.552e-02	-4.17	NFIC (nuclear factor I C)	protein interactions	4782	204	3	19454	50	TRPS1,SOX5,NFIA
1.552e-02	-4.17	CASK (calcium/calmodulin dependent serine protein kinase)	protein interactions	8573	204	3	19454	50	DTNA,ABLIM1,CADM1
1.554e-02	-4.16	TEC (tec protein tyrosine kinase)	protein interactions	7006	74	2	19454	50	MSI2,ERBB4
1.581e-02	-4.15	amino acid:proton symporter activity	molecular function	GO:0005280	6	1	18094	48	SLC25A18
1.581e-02	-4.15	steroid hormone binding	molecular function	GO:1990239	6	1	18094	48	ATP1A2
1.581e-02	-4.15	calcium-induced calcium release activity	molecular function	GO:0048763	6	1	18094	48	RYR3
1.581e-02	-4.15	sodium:bicarbonate symporter activity	molecular function	GO:0008510	6	1	18094	48	SLC4A4
1.594e-02	-4.14	TXNL4A (thioredoxin like 4A)	protein interactions	10907	75	2	19454	50	QKI,TPD52L1
1.600e-02	-4.13	other	COSMIC cancer mutations	other	14843	48	16828	49	NKAIN3,DTNA,PARD3,SLC1A3,NHSL1,NDRG2,NPAS3,FGFR3,MSI2,NTM,TPD52L1,RYR3,ZBTB20,CADM1,CAMK2G,RORA,TNIK,PTGDS,GLUL,SLC1A2,SLC4A4,CST3,TRPS1,ZNRF3,ABLIM1,LSAMP,CTNND2,TRPM3,NFIA,GPC5,COL5A3,ATP1A2,ATP13A4,SOX5,PREX2,MAML2,GPM6A,FBXL7,DOCK4,CDH20,CLU,AHCYL2,HPSE2,ERBB4,QKI,SASH1,SLC25A18,DAAM2
1.609e-02	-4.13	Ins145_P3_rcpt	interpro domains	IPR014821	6	1	18521	50	RYR3
1.609e-02	-4.13	EF-hand_dom_typ2	interpro domains	IPR015154	6	1	18521	50	DTNA
1.609e-02	-4.13	P-type_ATPase_IIC	interpro domains	IPR005775	6	1	18521	50	ATP1A2
1.609e-02	-4.13	EF-hand_dom_typ1	interpro domains	IPR015153	6	1	18521	50	DTNA
1.609e-02	-4.13	GF_recep_IV	interpro domains	IPR032778	6	1	18521	50	ERBB4
1.609e-02	-4.13	RIH_dom	interpro domains	IPR000699	6	1	18521	50	RYR3
1.609e-02	-4.13	Glypican	interpro domains	IPR001863	6	1	18521	50	GPC5
1.609e-02	-4.13	RIH_assoc-dom	interpro domains	IPR013662	6	1	18521	50	RYR3
1.609e-02	-4.13	Glypican_CS	interpro domains	IPR019803	6	1	18521	50	GPC5
1.609e-02	-4.13	Ryanodine_IP3_receptor	interpro domains	IPR015925	6	1	18521	50	RYR3
1.609e-02	-4.13	RyR/IP3R_RIH_dom_sf	interpro domains	IPR035910	6	1	18521	50	RYR3
1.622e-02	-4.12	salivary_gland	COSMIC cancer mutations	salivary_gland	1139	8	16828	49	TNIK,ERBB4,RYR3,MAML2,CAMK2G,FGFR3,RORA,CTNND2
1.627e-02	-4.12	sarcoplasmic reticulum	cellular component	GO:0016529	76	2	19108	49	RYR3,CAMK2G
1.633e-02	-4.11	BCL2L1 (BCL2 like 1)	protein interactions	598	208	3	19454	50	ABLIM1,RYR3,CLU
1.635e-02	-4.11	MIR200A (microRNA 200a)	protein interactions	406983	76	2	19454	50	QKI,MSI2
1.637e-02	-4.11	ERBB4-ERBB4 signaling pathway	biological process	GO:0038138	6	1	18204	50	ERBB4
1.637e-02	-4.11	vascular associated smooth muscle cell proliferation	biological process	GO:1990874	6	1	18204	50	NDRG2
1.637e-02	-4.11	regulation of protein autoubiquitination	biological process	GO:1902498	6	1	18204	50	SASH1
1.637e-02	-4.11	protein targeting to vacuole involved in autophagy	biological process	GO:0071211	6	1	18204	50	CLU
1.637e-02	-4.11	negative regulation of extracellular matrix disassembly	biological process	GO:0010716	6	1	18204	50	CST3
1.637e-02	-4.11	asymmetric neuroblast division	biological process	GO:0055059	6	1	18204	50	SOX5
1.637e-02	-4.11	gamma-aminobutyric acid biosynthetic process	biological process	GO:0009449	6	1	18204	50	SLC1A3
1.672e-02	-4.09	regulation of ATP metabolic process	biological process	GO:1903578	72	2	18204	50	ZBTB20,SLC4A4
1.674e-02	-4.09	RIH_assoc	pfam domains	PF08454	6	1	17795	50	RYR3
1.674e-02	-4.09	EF-hand_3	pfam domains	PF09069	6	1	17795	50	DTNA
1.674e-02	-4.09	EF-hand_2	pfam domains	PF09068	6	1	17795	50	DTNA
1.674e-02	-4.09	Glypican	pfam domains	PF01153	6	1	17795	50	GPC5
1.674e-02	-4.09	GF_recep_IV	pfam domains	PF14843	6	1	17795	50	ERBB4
1.674e-02	-4.09	RYDR_ITPR	pfam domains	PF01365	6	1	17795	50	RYR3
1.674e-02	-4.09	Ins145_P3_rec	pfam domains	PF08709	6	1	17795	50	RYR3
1.701e-02	-4.07	middle_lobe	COSMIC cancer mutations	middle_lobe	1382	9	16828	49	HPSE2,TRPM3,ATP1A2,ATP13A4,RYR3,ERBB4,SASH1,CTNND2,FGFR3
1.705e-02	-4.07	HAD_sf	interpro domains	IPR023214	74	2	18521	50	ATP13A4,ATP1A2
1.716e-02	-4.07	regulation of cartilage development	biological process	GO:0061035	73	2	18204	50	TRPS1,SOX5
1.717e-02	-4.06	MIR34C (microRNA 34c)	protein interactions	407042	78	2	19454	50	MSI2,QKI
1.719e-02	-4.06	Cell-cell junction organization	REACTOME pathways	R-HSA-421270	61	2	10285	34	CADM1,PARD3
1.735e-02	-4.05	skin-head_neck-malignant_melanoma	COSMIC cancer mutations	skin-head_neck-malignant_melanoma	6	1	16828	49	PREX2
1.735e-02	-4.05	skin-lower_leg-epidermal_nevus	COSMIC cancer mutations	skin-lower_leg-epidermal_nevus	6	1	16828	49	FGFR3
1.735e-02	-4.05	skin-back-other-seborrhoeic_keratosis	COSMIC cancer mutations	skin-back-other-seborrhoeic_keratosis	6	1	16828	49	FGFR3
1.735e-02	-4.05	skin-upper_leg-other-seborrhoeic_keratosis	COSMIC cancer mutations	skin-upper_leg-other-seborrhoeic_keratosis	6	1	16828	49	FGFR3
1.735e-02	-4.05	collecting_duct_carcinoma	COSMIC cancer mutations	collecting_duct_carcinoma	6	1	16828	49	FGFR3
1.735e-02	-4.05	skin-benign_melanocytic_nevus-lentiginous_nevus	COSMIC cancer mutations	skin-benign_melanocytic_nevus-lentiginous_nevus	6	1	16828	49	FGFR3
1.735e-02	-4.05	lentiginous_nevus	COSMIC cancer mutations	lentiginous_nevus	6	1	16828	49	FGFR3
1.735e-02	-4.05	skin-face-other-seborrhoeic_keratosis	COSMIC cancer mutations	skin-face-other-seborrhoeic_keratosis	6	1	16828	49	FGFR3
1.735e-02	-4.05	skin-lower_back-other-seborrhoeic_keratosis	COSMIC cancer mutations	skin-lower_back-other-seborrhoeic_keratosis	6	1	16828	49	FGFR3
1.735e-02	-4.05	skin-abdomen-other-seborrhoeic_keratosis	COSMIC cancer mutations	skin-abdomen-other-seborrhoeic_keratosis	6	1	16828	49	FGFR3
1.735e-02	-4.05	skin-in_situ_epithelial_neoplasm-Bowen_disease	COSMIC cancer mutations	skin-in_situ_epithelial_neoplasm-Bowen_disease	6	1	16828	49	FGFR3
1.735e-02	-4.05	skin-head_neck-epidermal_nevus	COSMIC cancer mutations	skin-head_neck-epidermal_nevus	6	1	16828	49	FGFR3
1.735e-02	-4.05	skin-in_situ_epithelial_neoplasm-actinic_keratosis	COSMIC cancer mutations	skin-in_situ_epithelial_neoplasm-actinic_keratosis	6	1	16828	49	FGFR3
1.735e-02	-4.05	skin-epidermal_nevus	COSMIC cancer mutations	skin-epidermal_nevus	6	1	16828	49	FGFR3
1.735e-02	-4.05	skin-arm-epidermal_nevus	COSMIC cancer mutations	skin-arm-epidermal_nevus	6	1	16828	49	FGFR3
1.735e-02	-4.05	kidney-carcinoma-collecting_duct_carcinoma	COSMIC cancer mutations	kidney-carcinoma-collecting_duct_carcinoma	6	1	16828	49	FGFR3
1.735e-02	-4.05	skin-adnexal_tumour-trichoblastoma	COSMIC cancer mutations	skin-adnexal_tumour-trichoblastoma	6	1	16828	49	FGFR3
1.735e-02	-4.05	skin-forearm-malignant_melanoma-superficial_spreading	COSMIC cancer mutations	skin-forearm-malignant_melanoma-superficial_spreading	6	1	16828	49	PREX2
1.735e-02	-4.05	autonomic_ganglia-paraganglioma-benign	COSMIC cancer mutations	autonomic_ganglia-paraganglioma-benign	6	1	16828	49	NHSL1
1.735e-02	-4.05	skin-flank-other-seborrhoeic_keratosis	COSMIC cancer mutations	skin-flank-other-seborrhoeic_keratosis	6	1	16828	49	FGFR3
1.735e-02	-4.05	skin-trunk-epidermal_nevus	COSMIC cancer mutations	skin-trunk-epidermal_nevus	6	1	16828	49	FGFR3
1.738e-02	-4.05	signaling	biological process	GO:0023052	4968	21	18204	50	TNIK,CLU,ERBB4,RYR3,PITPNC1,SLC1A2,ZNRF3,NFIA,DOCK4,DTNA,ATP1A2,FGFR3,SLC1A3,CAMK2G,CTNND2,NDRG2,RORA,PARD3,DAAM2,PREX2,MAML2
1.759e-02	-4.04	NUCB2 (nucleobindin 2)	protein interactions	4925	79	2	19454	50	GLUL,CLU
1.759e-02	-4.04	PRDM1 (PR/SET domain 1)	protein interactions	639	79	2	19454	50	TRPS1,NFIA
1.761e-02	-4.04	NCK1 (NCK adaptor protein 1)	protein interactions	4690	214	3	19454	50	NHSL1,ERBB4,TNIK
1.770e-02	-4.03	Glutamine synthetase/guanido kinase, catalytic domain	gene3d domains	3.30.590.10	6	1	14470	43	GLUL
1.770e-02	-4.03	IP3 receptor type 1 binding core, RIH domain	gene3d domains	1.25.10.30	6	1	14470	43	RYR3
1.786e-02	-4.03	FGF5 (fibroblast growth factor 5)	protein interactions	2250	7	1	19454	50	FGFR3
1.786e-02	-4.03	Pum2 (pumilio RNA-binding family member 2)	protein interactions	80913	7	1	19454	50	QKI
1.786e-02	-4.03	ABCC12 (ATP binding cassette subfamily C member 12)	protein interactions	94160	7	1	19454	50	NPAS3
1.786e-02	-4.03	CYP4F8 (cytochrome P450 family 4 subfamily F member 8)	protein interactions	11283	7	1	19454	50	CLU
1.786e-02	-4.03	SOAT2 (sterol O-acyltransferase 2)	protein interactions	8435	7	1	19454	50	CLU
1.786e-02	-4.03	C8B (complement C8 beta chain)	protein interactions	732	7	1	19454	50	CLU
1.786e-02	-4.03	Ahcyl1 (S-adenosylhomocysteine hydrolase-like 1)	protein interactions	229709	7	1	19454	50	AHCYL2
1.786e-02	-4.03	C7 (complement C7)	protein interactions	730	7	1	19454	50	CLU
1.786e-02	-4.03	ZBTB45 (zinc finger and BTB domain containing 45)	protein interactions	84878	7	1	19454	50	ZBTB20
1.801e-02	-4.02	PIAS3 (protein inhibitor of activated STAT 3)	protein interactions	10401	80	2	19454	50	GLUL,ERBB4
1.806e-02	-4.01	amino acid biosynthetic process	biological process	GO:0008652	75	2	18204	50	SLC1A3,GLUL
1.819e-02	-4.01	regulation of phosphorylation	biological process	GO:0042325	994	7	18204	50	ERBB4,TNIK,CADM1,FGFR3,TPD52L1,SASH1,PARD3
1.826e-02	-4.00	GFAP (glial fibrillary acidic protein)	protein interactions	2670	217	3	19454	50	RORA,ABLIM1,NKAIN3
1.843e-02	-3.99	calcium-dependent protein serine/threonine phosphatase activity	molecular function	GO:0004723	7	1	18094	48	CAMK2G
1.843e-02	-3.99	phosphatidic acid transfer activity	molecular function	GO:1990050	7	1	18094	48	PITPNC1
1.843e-02	-3.99	P-type sodium transporter activity	molecular function	GO:0008554	7	1	18094	48	ATP1A2
1.843e-02	-3.99	P-type sodium:potassium-exchanging transporter activity	molecular function	GO:0005391	7	1	18094	48	ATP1A2
1.843e-02	-3.99	SOX17 (SRY-box transcription factor 17)	protein interactions	64321	81	2	19454	50	TRPS1,NFIA
1.852e-02	-3.99	regulation of tyrosine phosphorylation of STAT protein	biological process	GO:0042509	76	2	18204	50	FGFR3,ERBB4
1.865e-02	-3.98	Protein_kinase_ATP_BS	interpro domains	IPR017441	377	4	18521	50	ERBB4,FGFR3,CAMK2G,TNIK
1.872e-02	-3.98	calcium ion transmembrane transport	biological process	GO:0070588	205	3	18204	50	RYR3,TRPM3,GPM6A
1.875e-02	-3.98	Rcpt_L-dom	interpro domains	IPR000494	7	1	18521	50	ERBB4
1.875e-02	-3.98	Furin-like_Cys-rich_dom	interpro domains	IPR006211	7	1	18521	50	ERBB4
1.875e-02	-3.98	Plakophilin/d_Catenin	interpro domains	IPR028435	7	1	18521	50	CTNND2
1.875e-02	-3.98	Rcpt_L-dom_sf	interpro domains	IPR036941	7	1	18521	50	ERBB4
1.875e-02	-3.98	Alpha-catenin/vinculin-like_sf	interpro domains	IPR036723	7	1	18521	50	CTNNA2
1.875e-02	-3.98	head development	biological process	GO:0060322	774	6	18204	50	ATP1A2,ERBB4,RORA,NDRG2,CTNNA2,SLC1A2
1.882e-02	-3.97	HAD-like_sf	interpro domains	IPR036412	78	2	18521	50	ATP1A2,ATP13A4
1.896e-02	-3.97	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm	7307	29	16828	49	HPSE2,AHCYL2,QKI,ERBB4,SASH1,DAAM2,CTNND2,ABLIM1,LSAMP,CDH20,TNIK,CLU,SLC1A2,RYR3,SOX5,ATP13A4,TPD52L1,GPM6A,FBXL7,CADM1,MAML2,PREX2,RORA,NKAIN3,PARD3,GPC5,SLC1A3,NHSL1,COL5A3
1.902e-02	-3.96	testis	COSMIC cancer mutations	testis	733	6	16828	49	CAMK2G,PREX2,FGFR3,TRPS1,TNIK,ERBB4
1.907e-02	-3.96	positive regulation of transcription of Notch receptor target	biological process	GO:0007221	7	1	18204	50	MAML2
1.907e-02	-3.96	cellular response to magnesium ion	biological process	GO:0071286	7	1	18204	50	RYR3
1.907e-02	-3.96	negative regulation of Arp2/3 complex-mediated actin nucleation	biological process	GO:0034316	7	1	18204	50	CTNNA2
1.907e-02	-3.96	regulation of 3'-UTR-mediated mRNA stabilization	biological process	GO:1905868	7	1	18204	50	QKI
1.907e-02	-3.96	regulation of male germ cell proliferation	biological process	GO:2000254	7	1	18204	50	PTGDS
1.907e-02	-3.96	glial cell fate specification	biological process	GO:0021780	7	1	18204	50	NFIA
1.907e-02	-3.96	S-adenosylmethionine cycle	biological process	GO:0033353	7	1	18204	50	AHCYL2
1.907e-02	-3.96	podocyte cell migration	biological process	GO:0090521	7	1	18204	50	DAAM2
1.907e-02	-3.96	chaperone-mediated autophagy	biological process	GO:0061684	7	1	18204	50	CLU
1.907e-02	-3.96	negative regulation of non-canonical Wnt signaling pathway	biological process	GO:2000051	7	1	18204	50	ZNRF3
1.909e-02	-3.96	cell communication	biological process	GO:0007154	5010	21	18204	50	RYR3,PITPNC1,ERBB4,CLU,TNIK,SLC1A2,ZNRF3,DOCK4,NFIA,ATP1A2,FGFR3,SLC1A3,DTNA,CTNND2,NDRG2,CAMK2G,PARD3,DAAM2,RORA,PREX2,MAML2
1.925e-02	-3.95	RHOB (ras homolog family member B)	protein interactions	388	832	6	19454	50	TNIK,PARD3,SLC1A3,ABLIM1,DTNA,AHCYL2
1.930e-02	-3.95	PAX2 (paired box 2)	protein interactions	5076	83	2	19454	50	TRPS1,NFIA
1.930e-02	-3.95	DNM3 (dynamin 3)	protein interactions	26052	83	2	19454	50	GPM6A,FGFR3
1.937e-02	-3.94	Constitutive Signaling by Aberrant PI3K in Cancer	REACTOME pathways	R-HSA-2219530	65	2	10285	34	ERBB4,FGFR3
1.944e-02	-3.94	positive regulation of carbohydrate metabolic process	biological process	GO:0045913	78	2	18204	50	ZBTB20,SLC4A4
1.951e-02	-3.94	Recep_L_domain	pfam domains	PF01030	7	1	17795	50	ERBB4
1.951e-02	-3.94	Furin-like	pfam domains	PF00757	7	1	17795	50	ERBB4
1.954e-02	-3.94	GLYPICAN	prosite domains	PS01207	6	1	12186	40	GPC5
1.954e-02	-3.94	transmembrane receptor protein kinase activity	molecular function	GO:0019199	81	2	18094	48	ERBB4,FGFR3
1.962e-02	-3.93	Axon guidance	KEGG pathways	ko04360	174	3	7161	24	CAMK2G,ABLIM1,PARD3
1.962e-02	-3.93	Axon guidance	KEGG pathways	hsa04360	174	3	7161	24	PARD3,ABLIM1,CAMK2G
1.974e-02	-3.93	Tyr_kinase_cat_dom	interpro domains	IPR020635	80	2	18521	50	FGFR3,ERBB4
1.977e-02	-3.92	chondrosarcoma	COSMIC cancer mutations	chondrosarcoma	1181	8	16828	49	SLC4A4,COL5A3,ERBB4,LSAMP,HPSE2,DAAM2,DOCK4,NDRG2
1.985e-02	-3.92	MAPRE3 (microtubule associated protein RP/EB family member 3)	protein interactions	22924	224	3	19454	50	DOCK4,ABLIM1,GPM6A
1.991e-02	-3.92	regulation of glial cell differentiation	biological process	GO:0045685	79	2	18204	50	DAAM2,QKI
2.004e-02	-3.91	somatodendritic compartment	cellular component	GO:0036477	842	6	19108	49	ATP1A2,GPM6A,CADM1,CTNND2,CLU,SLC1A3
2.008e-02	-3.91	KLF3 (KLF transcription factor 3)	protein interactions	51274	225	3	19454	50	NFIA,SOX5,TRPS1
2.018e-02	-3.90	CCND3 (cyclin D3)	protein interactions	896	85	2	19454	50	QKI,CLU
2.021e-02	-3.90	positive regulation of protein phosphorylation	biological process	GO:0001934	574	5	18204	50	FGFR3,TPD52L1,TNIK,ERBB4,SASH1
2.021e-02	-3.90	skin-neck-other-seborrhoeic_keratosis	COSMIC cancer mutations	skin-neck-other-seborrhoeic_keratosis	7	1	16828	49	FGFR3
2.021e-02	-3.90	skin-face-malignant_melanoma-nodular	COSMIC cancer mutations	skin-face-malignant_melanoma-nodular	7	1	16828	49	PREX2
2.021e-02	-3.90	skin-benign_melanocytic_nevus-intradermal	COSMIC cancer mutations	skin-benign_melanocytic_nevus-intradermal	7	1	16828	49	FGFR3
2.021e-02	-3.90	skin-shoulder-other-seborrhoeic_keratosis	COSMIC cancer mutations	skin-shoulder-other-seborrhoeic_keratosis	7	1	16828	49	FGFR3
2.021e-02	-3.90	skin-benign_melanocytic_nevus-compound	COSMIC cancer mutations	skin-benign_melanocytic_nevus-compound	7	1	16828	49	FGFR3
2.021e-02	-3.90	skin-other-nevus_sebaceous	COSMIC cancer mutations	skin-other-nevus_sebaceous	7	1	16828	49	FGFR3
2.021e-02	-3.90	urinary_tract-carcinoma-transitional_cell_carcinoma	COSMIC cancer mutations	urinary_tract-carcinoma-transitional_cell_carcinoma	7	1	16828	49	FGFR3
2.021e-02	-3.90	skin-face-adnexal_tumour-malignant_adnexal_tumour	COSMIC cancer mutations	skin-face-adnexal_tumour-malignant_adnexal_tumour	7	1	16828	49	FGFR3
2.021e-02	-3.90	skin-adnexal_tumour-trichilemmoma	COSMIC cancer mutations	skin-adnexal_tumour-trichilemmoma	7	1	16828	49	FGFR3
2.021e-02	-3.90	nevus_sebaceous	COSMIC cancer mutations	nevus_sebaceous	7	1	16828	49	FGFR3
2.021e-02	-3.90	skin-upper_leg-malignant_melanoma-nodular	COSMIC cancer mutations	skin-upper_leg-malignant_melanoma-nodular	7	1	16828	49	PREX2
2.021e-02	-3.90	trichilemmoma	COSMIC cancer mutations	trichilemmoma	7	1	16828	49	FGFR3
2.021e-02	-3.90	skin-chest-other-seborrhoeic_keratosis	COSMIC cancer mutations	skin-chest-other-seborrhoeic_keratosis	7	1	16828	49	FGFR3
2.034e-02	-3.90	spherical high-density lipoprotein particle	cellular component	GO:0034366	8	1	19108	49	CLU
2.035e-02	-3.89	HAD superfamily/HAD-like	gene3d domains	3.40.50.1000	74	2	14470	43	ATP1A2,ATP13A4
2.038e-02	-3.89	Chmp2a (charged multivesicular body protein 2A)	protein interactions	68953	8	1	19454	50	CLU
2.038e-02	-3.89	PTGER1 (prostaglandin E receptor 1)	protein interactions	5731	8	1	19454	50	PTGDS
2.038e-02	-3.89	LHB (luteinizing hormone subunit beta)	protein interactions	3972	8	1	19454	50	NTM
2.038e-02	-3.89	DEPP1 (DEPP autophagy regulator 1)	protein interactions	11067	8	1	19454	50	QKI
2.042e-02	-3.89	positive regulation of transferase activity	biological process	GO:0051347	381	4	18204	50	SASH1,TPD52L1,FGFR3,ERBB4
2.043e-02	-3.89	acral_lentiginous	COSMIC cancer mutations	acral_lentiginous	745	6	16828	49	CDH20,PREX2,PARD3,ATP13A4,ERBB4,FGFR3
2.062e-02	-3.88	Receptor L-domain	gene3d domains	3.80.20.20	7	1	14470	43	ERBB4
2.079e-02	-3.87	haematopoietic_and_lymphoid_tissue-lymph_node-lymphoid_neoplasm-diffuse_large_B_cell_lymphoma	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue-lymph_node-lymphoid_neoplasm-diffuse_large_B_cell_lymphoma	748	6	16828	49	TRPS1,DTNA,SLC1A3,PARD3,SOX5,CTNND2
2.084e-02	-3.87	dendrite	cellular component	GO:0030425	620	5	19108	49	CTNND2,CLU,CADM1,GPM6A,ATP1A2
2.087e-02	-3.87	adult locomotory behavior	biological process	GO:0008344	81	2	18204	50	PREX2,ATP1A2
2.103e-02	-3.86	sodium ion binding	molecular function	GO:0031402	8	1	18094	48	ATP1A2
2.103e-02	-3.86	P-type potassium transmembrane transporter activity	molecular function	GO:0008556	8	1	18094	48	ATP1A2
2.103e-02	-3.86	glutamate binding	molecular function	GO:0016595	8	1	18094	48	SLC1A3
2.105e-02	-3.86	glutamatergic synapse	cellular component	GO:0098978	412	4	19108	49	GPM6A,SLC1A2,ERBB4,TNIK
2.108e-02	-3.86	MIR141 (microRNA 141)	protein interactions	406933	87	2	19454	50	MSI2,QKI
2.108e-02	-3.86	ZNF608 (zinc finger protein 608)	protein interactions	57507	87	2	19454	50	NFIA,SOX5
2.108e-02	-3.86	Kctd5 (potassium channel tetramerisation domain containing 5)	protein interactions	69259	87	2	19454	50	SLC1A3,TRPS1
2.108e-02	-3.86	FGR (FGR proto-oncogene, Src family tyrosine kinase)	protein interactions	2268	87	2	19454	50	ERBB4,SLC25A18
2.108e-02	-3.86	NHLH1 (nescient helix-loop-helix 1)	protein interactions	4807	87	2	19454	50	TRPS1,NFIA
2.110e-02	-3.86	dendritic tree	cellular component	GO:0097447	622	5	19108	49	CADM1,ATP1A2,GPM6A,CLU,CTNND2
2.127e-02	-3.85	DST (dystonin)	protein interactions	667	230	3	19454	50	PARD3,TNIK,ATP1A2
2.140e-02	-3.84	TRPM_SLOG	interpro domains	IPR041491	8	1	18521	50	TRPM3
2.140e-02	-3.84	DAD_dom	interpro domains	IPR014767	8	1	18521	50	DAAM2
2.140e-02	-3.84	Villin_headpiece_dom_sf	interpro domains	IPR036886	8	1	18521	50	ABLIM1
2.140e-02	-3.84	Gln_synth/guanido_kin_cat_dom	interpro domains	IPR014746	8	1	18521	50	GLUL
2.140e-02	-3.84	Villin_headpiece	interpro domains	IPR003128	8	1	18521	50	ABLIM1
2.140e-02	-3.84	positive regulation of cellular process	biological process	GO:0048522	5719	23	18204	50	SOX5,SLC1A2,GPC5,CADM1,GPM6A,NFIA,SASH1,ZBTB20,SLC1A3,MAML2,SLC4A4,HPSE2,TNIK,CLU,ERBB4,DOCK4,TPD52L1,FGFR3,QKI,NPAS3,DAAM2,PARD3,RORA
2.153e-02	-3.84	Ig_sub	interpro domains	IPR003599	394	4	18521	50	LSAMP,CADM1,NTM,FGFR3
2.176e-02	-3.83	Calcium signaling pathway	KEGG pathways	hsa04020	181	3	7161	24	CAMK2G,ERBB4,RYR3
2.176e-02	-3.83	Calcium signaling pathway	KEGG pathways	ko04020	181	3	7161	24	ERBB4,CAMK2G,RYR3
2.177e-02	-3.83	regulation of L-glutamate import across plasma membrane	biological process	GO:0002036	8	1	18204	50	ATP1A2
2.177e-02	-3.83	regulation of germ cell proliferation	biological process	GO:1905936	8	1	18204	50	PTGDS
2.177e-02	-3.83	protein import	biological process	GO:0017038	8	1	18204	50	CLU
2.177e-02	-3.83	smooth muscle cell proliferation	biological process	GO:0048659	8	1	18204	50	NDRG2
2.177e-02	-3.83	cell proliferation in external granule layer	biological process	GO:0021924	8	1	18204	50	RORA
2.177e-02	-3.83	regulation of synapse structural plasticity	biological process	GO:0051823	8	1	18204	50	CTNNA2
2.177e-02	-3.83	cell proliferation in hindbrain	biological process	GO:0021534	8	1	18204	50	RORA
2.177e-02	-3.83	ERBB4 signaling pathway	biological process	GO:0038130	8	1	18204	50	ERBB4
2.177e-02	-3.83	gamma-aminobutyric acid metabolic process	biological process	GO:0009448	8	1	18204	50	SLC1A3
2.177e-02	-3.83	cerebellar granule cell precursor proliferation	biological process	GO:0021930	8	1	18204	50	RORA
2.177e-02	-3.83	glutamate catabolic process	biological process	GO:0006538	8	1	18204	50	GLUL
2.184e-02	-3.82	positive regulation of MAP kinase activity	biological process	GO:0043406	83	2	18204	50	SASH1,TPD52L1
2.185e-02	-3.82	immune effector process	biological process	GO:0002252	389	4	18204	50	PTGDS,RORA,CADM1,CLU
2.185e-02	-3.82	endometrium-carcinoma-serous_carcinoma	COSMIC cancer mutations	endometrium-carcinoma-serous_carcinoma	1442	9	16828	49	TRPM3,TRPS1,TNIK,RYR3,PARD3,SLC4A4,GPC5,CTNND2,LSAMP
2.199e-02	-3.82	SOX10 (SRY-box transcription factor 10)	protein interactions	6663	89	2	19454	50	TRPS1,NFIA
2.199e-02	-3.82	PLEKHA2 (pleckstrin homology domain containing A2)	protein interactions	59339	89	2	19454	50	AHCYL2,DTNA
2.200e-02	-3.82	TNS2 (tensin 2)	protein interactions	23371	233	3	19454	50	GLUL,DTNA,ERBB4
2.207e-02	-3.81	Endochondral Ossification	WikiPathways	WP474	65	2	5310	19	FGFR3,SOX5
2.219e-02	-3.81	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-T_cell_large_granular_lymphocytic_leukaemia	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-T_cell_large_granular_lymphocytic_leukaemia	79	2	16828	49	MAML2,CADM1
2.224e-02	-3.81	HMG20A (high mobility group 20A)	protein interactions	10363	234	3	19454	50	NFIA,DTNA,SOX5
2.226e-02	-3.80	LSDAT_euk	pfam domains	PF18139	8	1	17795	50	TRPM3
2.226e-02	-3.80	VHP	pfam domains	PF02209	8	1	17795	50	ABLIM1
2.233e-02	-3.80	regulation of sodium ion transport	biological process	GO:0002028	84	2	18204	50	NKAIN3,ATP1A2
2.233e-02	-3.80	stem cell development	biological process	GO:0048864	84	2	18204	50	MSI2,ERBB4
2.246e-02	-3.80	CTDSPL (CTD small phosphatase like)	protein interactions	10217	90	2	19454	50	DTNA,CADM1
2.246e-02	-3.80	FGFR1OP2 (FGFR1 oncogene partner 2)	protein interactions	26127	90	2	19454	50	TNIK,CAMK2G
2.272e-02	-3.78	human chr6q26	chromosome location	human chr6q26	12	1	26134	50	QKI
2.277e-02	-3.78	leukocyte mediated immunity	biological process	GO:0002443	221	3	18204	50	PTGDS,CLU,CADM1
2.283e-02	-3.78	chondrocyte differentiation	biological process	GO:0002062	85	2	18204	50	SOX5,FGFR3
2.290e-02	-3.78	CAMK2N1 (calcium/calmodulin dependent protein kinase II inhibitor 1)	protein interactions	55450	9	1	19454	50	CAMK2G
2.290e-02	-3.78	GUSBP1 (GUSB pseudogene 1)	protein interactions	728411	9	1	19454	50	FGFR3
2.290e-02	-3.78	Ywhag (tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide)	protein interactions	22628	9	1	19454	50	QKI
2.290e-02	-3.78	KLB (klotho beta)	protein interactions	152831	9	1	19454	50	FGFR3
2.290e-02	-3.78	MUC4 (mucin 4, cell surface associated)	protein interactions	4585	9	1	19454	50	ERBB4
2.290e-02	-3.78	Tyw3 (tRNA-yW synthesizing protein 3 homolog (S. cerevisiae))	protein interactions	209584	9	1	19454	50	CTNNA2
2.292e-02	-3.78	Nectin/Necl trans heterodimerization	REACTOME pathways	R-HSA-420597	7	1	10285	34	CADM1
2.292e-02	-3.78	FGFR3b ligand binding and activation	REACTOME pathways	R-HSA-190371	7	1	10285	34	FGFR3
2.292e-02	-3.78	PTPN21 (protein tyrosine phosphatase non-receptor type 21)	protein interactions	11099	91	2	19454	50	AHCYL2,ERBB4
2.292e-02	-3.78	DGUOK (deoxyguanosine kinase)	protein interactions	1716	91	2	19454	50	GPM6A,NTM
2.292e-02	-3.78	FOXI1 (forkhead box I1)	protein interactions	2299	91	2	19454	50	TRPS1,NFIA
2.299e-02	-3.77	CAMK2A (calcium/calmodulin dependent protein kinase II alpha)	protein interactions	815	237	3	19454	50	CAMK2G,SOX5,GPM6A
2.306e-02	-3.77	cervix-in_situ_neoplasm-cervical_intraepithelial_neoplasia_Grade_I	COSMIC cancer mutations	cervix-in_situ_neoplasm-cervical_intraepithelial_neoplasia_Grade_I	8	1	16828	49	FGFR3
2.306e-02	-3.77	central_nervous_system-chiasm-glioma-astrocytoma_Grade_I	COSMIC cancer mutations	central_nervous_system-chiasm-glioma-astrocytoma_Grade_I	8	1	16828	49	QKI
2.306e-02	-3.77	urinary_tract-ureter-carcinoma-transitional_cell_carcinoma	COSMIC cancer mutations	urinary_tract-ureter-carcinoma-transitional_cell_carcinoma	8	1	16828	49	FGFR3
2.306e-02	-3.77	cervical_intraepithelial_neoplasia_Grade_I	COSMIC cancer mutations	cervical_intraepithelial_neoplasia_Grade_I	8	1	16828	49	FGFR3
2.306e-02	-3.77	junctional	COSMIC cancer mutations	junctional	8	1	16828	49	FGFR3
2.306e-02	-3.77	skin-chest-malignant_melanoma-nodular	COSMIC cancer mutations	skin-chest-malignant_melanoma-nodular	8	1	16828	49	PREX2
2.306e-02	-3.77	trichoblastoma	COSMIC cancer mutations	trichoblastoma	8	1	16828	49	FGFR3
2.306e-02	-3.77	actinic_keratosis	COSMIC cancer mutations	actinic_keratosis	8	1	16828	49	FGFR3
2.324e-02	-3.76	Bile secretion	KEGG pathways	hsa04976	71	2	7161	24	ATP1A2,SLC4A4
2.324e-02	-3.76	Bile secretion	KEGG pathways	ko04976	71	2	7161	24	SLC4A4,ATP1A2
2.324e-02	-3.76	MBNL1 (muscleblind like splicing regulator 1)	protein interactions	4154	238	3	19454	50	GLUL,NDRG2,QKI
2.325e-02	-3.76	T_cell_large_granular_lymphocytic_leukaemia	COSMIC cancer mutations	T_cell_large_granular_lymphocytic_leukaemia	81	2	16828	49	MAML2,CADM1
2.331e-02	-3.76	amyloid-beta binding	molecular function	GO:0001540	89	2	18094	48	CST3,CLU
2.339e-02	-3.76	SOX9 (SRY-box transcription factor 9)	protein interactions	6662	92	2	19454	50	NFIA,TRPS1
2.339e-02	-3.76	POTEI (POTE ankyrin domain family member I)	protein interactions	653269	92	2	19454	50	FGFR3,DTNA
2.339e-02	-3.76	FNTA (farnesyltransferase, CAAX box, subunit alpha)	protein interactions	2339	92	2	19454	50	FGFR3,TNIK
2.352e-02	-3.75	organic anion transport	biological process	GO:0015711	398	4	18204	50	SLC25A18,SLC1A3,SLC1A2,SLC4A4
2.353e-02	-3.75	Villin headpiece domain	gene3d domains	1.10.950.10	8	1	14470	43	ABLIM1
2.363e-02	-3.75	L-aspartate transmembrane transporter activity	molecular function	GO:0015183	9	1	18094	48	SLC25A18
2.367e-02	-3.74	regulation of signaling	biological process	GO:0023051	3534	16	18204	50	FGFR3,TPD52L1,SLC1A3,ATP1A2,NDRG2,SASH1,CTNND2,DAAM2,RORA,PREX2,GPC5,ERBB4,CLU,CADM1,TNIK,ZNRF3
2.386e-02	-3.74	Adherens junction	KEGG pathways	ko04520	72	2	7161	24	CTNNA2,PARD3
2.386e-02	-3.74	Adherens junction	KEGG pathways	hsa04520	72	2	7161	24	CTNNA2,PARD3
2.387e-02	-3.74	TEX11 (testis expressed 11)	protein interactions	56159	93	2	19454	50	QKI,SOX5
2.387e-02	-3.74	MIR19B2 (microRNA 19b-2)	protein interactions	406981	93	2	19454	50	MSI2,QKI
2.387e-02	-3.74	MPDZ (multiple PDZ domain crumbs cell polarity complex component)	protein interactions	8777	93	2	19454	50	FGFR3,PARD3
2.387e-02	-3.74	SSBP2 (single stranded DNA binding protein 2)	protein interactions	23635	93	2	19454	50	NDRG2,GLUL
2.387e-02	-3.74	RBM23 (RNA binding motif protein 23)	protein interactions	55147	93	2	19454	50	AHCYL2,QKI
2.387e-02	-3.74	DMRTB1 (DMRT like family B with proline rich C-terminal 1)	protein interactions	63948	93	2	19454	50	MSI2,QKI
2.388e-02	-3.73	hand	COSMIC cancer mutations	hand	566	5	16828	49	PREX2,COL5A3,SLC4A4,FGFR3,ERBB4
2.404e-02	-3.73	GTPase-bd	interpro domains	IPR010473	9	1	18521	50	DAAM2
2.404e-02	-3.73	FH3_dom	interpro domains	IPR010472	9	1	18521	50	DAAM2
2.404e-02	-3.73	Prot_inh_cystat_CS	interpro domains	IPR018073	9	1	18521	50	CST3
2.404e-02	-3.73	Band3_cytoplasmic_dom	interpro domains	IPR013769	9	1	18521	50	SLC4A4
2.408e-02	-3.73	regulation of cell communication	biological process	GO:0010646	3541	16	18204	50	ZNRF3,TNIK,CADM1,ERBB4,CLU,GPC5,RORA,DAAM2,PREX2,FGFR3,SLC1A3,TPD52L1,ATP1A2,NDRG2,CTNND2,SASH1
2.424e-02	-3.72	GATAZNFINGER	prints domains	PR00619	8	1	5227	16	TRPS1
2.424e-02	-3.72	LIPOCALIN	prints domains	PR00179	8	1	5227	16	PTGDS
2.435e-02	-3.72	FOXP4 (forkhead box P4)	protein interactions	116113	94	2	19454	50	SOX5,NFIA
2.435e-02	-3.72	QSER1 (glutamine and serine rich 1)	protein interactions	79832	94	2	19454	50	NFIA,SOX5
2.435e-02	-3.72	GRIN1 (glutamate ionotropic receptor NMDA type subunit 1)	protein interactions	2902	94	2	19454	50	FGFR3,CAMK2G
2.435e-02	-3.72	TTR (transthyretin)	protein interactions	7276	94	2	19454	50	CLU,CTNND2
2.435e-02	-3.72	WWC1 (WW and C2 domain containing 1)	protein interactions	23286	94	2	19454	50	ABLIM1,TNIK
2.446e-02	-3.71	microglial cell proliferation	biological process	GO:0061518	9	1	18204	50	CLU
2.446e-02	-3.71	polyamine transmembrane transport	biological process	GO:1902047	9	1	18204	50	ATP13A4
2.446e-02	-3.71	negative regulation of actin nucleation	biological process	GO:0051126	9	1	18204	50	CTNNA2
2.446e-02	-3.71	release of sequestered calcium ion into cytosol by sarcoplasmic reticulum	biological process	GO:0014808	9	1	18204	50	RYR3
2.446e-02	-3.71	activated T cell proliferation	biological process	GO:0050798	9	1	18204	50	CADM1
2.446e-02	-3.71	regulation of protein localization to nucleolus	biological process	GO:1904749	9	1	18204	50	GLUL
2.446e-02	-3.71	hindbrain radial glia guided cell migration	biological process	GO:0021932	9	1	18204	50	CTNNA2
2.446e-02	-3.71	regulation of vascular associated smooth muscle contraction	biological process	GO:0003056	9	1	18204	50	DOCK4
2.446e-02	-3.71	negative regulation of striated muscle contraction	biological process	GO:0045988	9	1	18204	50	ATP1A2
2.446e-02	-3.71	macrophage proliferation	biological process	GO:0061517	9	1	18204	50	CLU
2.446e-02	-3.71	cyclooxygenase pathway	biological process	GO:0019371	9	1	18204	50	PTGDS
2.456e-02	-3.71	membrane	cellular component	GO:0016020	9220	31	19108	49	CLU,GLUL,CDH20,CTNNA2,PTGDS,HPSE2,ATP1A2,GPC5,SLC1A3,FGFR3,PREX2,DOCK4,DTNA,LSAMP,CTNND2,SLC25A18,ERBB4,GPM6A,CAMK2G,PARD3,SLC1A2,TNIK,RYR3,TRPM3,NKAIN3,ZNRF3,CST3,SLC4A4,NTM,CADM1,ATP13A4
2.459e-02	-3.71	human chr5p15.1	chromosome location	human chr5p15.1	13	1	26134	50	FBXL7
2.468e-02	-3.70	bronchioloalveolar_adenocarcinoma	COSMIC cancer mutations	bronchioloalveolar_adenocarcinoma	778	6	16828	49	CAMK2G,TNIK,SOX5,CTNND2,FGFR3,ERBB4
2.468e-02	-3.70	lung-carcinoma-bronchioloalveolar_adenocarcinoma	COSMIC cancer mutations	lung-carcinoma-bronchioloalveolar_adenocarcinoma	778	6	16828	49	FGFR3,CTNND2,CAMK2G,ERBB4,SOX5,TNIK
2.483e-02	-3.70	STRIP1 (striatin interacting protein 1)	protein interactions	85369	95	2	19454	50	TNIK,CAMK2G
2.501e-02	-3.69	Drf_FH3	pfam domains	PF06367	9	1	17795	50	DAAM2
2.501e-02	-3.69	Drf_GBD	pfam domains	PF06371	9	1	17795	50	DAAM2
2.501e-02	-3.69	Band_3_cyto	pfam domains	PF07565	9	1	17795	50	SLC4A4
2.521e-02	-3.68	sarcoplasm	cellular component	GO:0016528	96	2	19108	49	CAMK2G,RYR3
2.532e-02	-3.68	SOCS2 (suppressor of cytokine signaling 2)	protein interactions	8835	96	2	19454	50	GLUL,ERBB4
2.532e-02	-3.68	E7 (E7 protein)	protein interactions	1489369	96	2	19454	50	SASH1,QKI
2.534e-02	-3.68	g-Secretase Mediated ErbB4 Signalling Pathway	SMPDB pathways	SMP0089975	7	1	1369	5	ERBB4
2.539e-02	-3.67	regulation of purine nucleotide metabolic process	biological process	GO:1900542	90	2	18204	50	SLC4A4,ZBTB20
2.541e-02	-3.67	Hsp90aa1 (heat shock protein 90, alpha (cytosolic), class A member 1)	protein interactions	15519	10	1	19454	50	QKI
2.541e-02	-3.67	SLC8A2 (solute carrier family 8 member A2)	protein interactions	6543	10	1	19454	50	GPM6A
2.541e-02	-3.67	PTPRT (protein tyrosine phosphatase receptor type T)	protein interactions	11122	10	1	19454	50	ERBB4
2.541e-02	-3.67	CALB2 (calbindin 2)	protein interactions	794	10	1	19454	50	GPM6A
2.541e-02	-3.67	Vbp1 (von Hippel-Lindau binding protein 1)	protein interactions	22327	10	1	19454	50	ABLIM1
2.541e-02	-3.67	EREG (epiregulin)	protein interactions	2069	10	1	19454	50	ERBB4
2.541e-02	-3.67	Mrpl13 (mitochondrial ribosomal protein L13)	protein interactions	68537	10	1	19454	50	QKI
2.541e-02	-3.67	GSG1 (germ cell associated 1)	protein interactions	83445	10	1	19454	50	PITPNC1
2.547e-02	-3.67	YWHAZ (tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein zeta)	protein interactions	7534	1138	7	19454	50	ABLIM1,SASH1,CAMK2G,PITPNC1,PARD3,NHSL1,TPD52L1
2.568e-02	-3.66	spindle	COSMIC cancer mutations	spindle	386	4	16828	49	PREX2,TRPM3,FGFR3,CTNND2
2.574e-02	-3.66	Gastric acid secretion	KEGG pathways	hsa04971	75	2	7161	24	CAMK2G,ATP1A2
2.574e-02	-3.66	Gastric acid secretion	KEGG pathways	ko04971	75	2	7161	24	ATP1A2,CAMK2G
2.581e-02	-3.66	SOCS3 (suppressor of cytokine signaling 3)	protein interactions	9021	97	2	19454	50	ERBB4,FGFR3
2.581e-02	-3.66	PLCB3 (phospholipase C beta 3)	protein interactions	5331	97	2	19454	50	CAMK2G,PARD3
2.581e-02	-3.66	BTG3 (BTG anti-proliferation factor 3)	protein interactions	10950	97	2	19454	50	CLU,GLUL
2.581e-02	-3.66	ABL2 (ABL proto-oncogene 2, non-receptor tyrosine kinase)	protein interactions	27	97	2	19454	50	ERBB4,TPD52L1
2.581e-02	-3.66	connective tissue development	biological process	GO:0061448	232	3	18204	50	NFIA,SOX5,FGFR3
2.585e-02	-3.66	NCOR2 (nuclear receptor corepressor 2)	protein interactions	9612	248	3	19454	50	NFIA,TNIK,SOX5
2.591e-02	-3.65	compound	COSMIC cancer mutations	compound	9	1	16828	49	FGFR3
2.591e-02	-3.65	Bowen_disease	COSMIC cancer mutations	Bowen_disease	9	1	16828	49	FGFR3
2.591e-02	-3.65	skin-chest-malignant_melanoma-superficial_spreading	COSMIC cancer mutations	skin-chest-malignant_melanoma-superficial_spreading	9	1	16828	49	PREX2
2.591e-02	-3.65	skin-other-seborrhoeic_keratosis	COSMIC cancer mutations	skin-other-seborrhoeic_keratosis	9	1	16828	49	FGFR3
2.591e-02	-3.65	epidermal_nevus	COSMIC cancer mutations	epidermal_nevus	9	1	16828	49	FGFR3
2.591e-02	-3.65	skin-benign_melanocytic_nevus-congenital	COSMIC cancer mutations	skin-benign_melanocytic_nevus-congenital	9	1	16828	49	FGFR3
2.591e-02	-3.65	in_situ_epithelial_neoplasm	COSMIC cancer mutations	in_situ_epithelial_neoplasm	9	1	16828	49	FGFR3
2.591e-02	-3.65	skin-upper_leg-malignant_melanoma-superficial_spreading	COSMIC cancer mutations	skin-upper_leg-malignant_melanoma-superficial_spreading	9	1	16828	49	PREX2
2.591e-02	-3.65	ovary-low_malignant_potential_(borderline)_tumour-Brenner_tumour	COSMIC cancer mutations	ovary-low_malignant_potential_(borderline)_tumour-Brenner_tumour	9	1	16828	49	FGFR3
2.592e-02	-3.65	regulation of nucleotide metabolic process	biological process	GO:0006140	91	2	18204	50	SLC4A4,ZBTB20
2.597e-02	-3.65	DAD	prosite domains	PS51231	8	1	12186	40	DAAM2
2.597e-02	-3.65	HP	prosite domains	PS51089	8	1	12186	40	ABLIM1
2.597e-02	-3.65	GATA_ZN_FINGER_1	prosite domains	PS00344	8	1	12186	40	TRPS1
2.612e-02	-3.65	PNMA2 (PNMA family member 2)	protein interactions	10687	249	3	19454	50	CAMK2G,PARD3,GLUL
2.612e-02	-3.65	MYO1B (myosin IB)	protein interactions	4430	249	3	19454	50	PARD3,CAMK2G,FGFR3
2.615e-02	-3.64	Release of Hh-Np from the secreting cell	REACTOME pathways	R-HSA-5362798	8	1	10285	34	GPC5
2.615e-02	-3.64	Downregulation of ERBB4 signaling	REACTOME pathways	R-HSA-1253288	8	1	10285	34	ERBB4
2.622e-02	-3.64	phosphatidylinositol transfer activity	molecular function	GO:0008526	10	1	18094	48	PITPNC1
2.622e-02	-3.64	polyamine transmembrane transporter activity	molecular function	GO:0015203	10	1	18094	48	ATP13A4
2.631e-02	-3.64	MED27 (mediator complex subunit 27)	protein interactions	9442	98	2	19454	50	QKI,SOX5
2.631e-02	-3.64	FRS2 (fibroblast growth factor receptor substrate 2)	protein interactions	10818	98	2	19454	50	FGFR3,PARD3
2.631e-02	-3.64	DNAAF2 (dynein axonemal assembly factor 2)	protein interactions	55172	98	2	19454	50	GPM6A,LSAMP
2.637e-02	-3.64	intracellular signaling cassette	biological process	GO:0141124	837	6	18204	50	DOCK4,PREX2,FGFR3,RYR3,ATP1A2,TNIK
2.645e-02	-3.63	protein tetramerization	biological process	GO:0051262	92	2	18204	50	TRPM3,RYR3
2.668e-02	-3.62	PTrfase/Anion_transptr	interpro domains	IPR016152	10	1	18521	50	SLC4A4
2.668e-02	-3.62	PAS_fold_3	interpro domains	IPR013655	10	1	18521	50	NPAS3
2.668e-02	-3.62	HCO3_transpt-like_TM_dom	interpro domains	IPR011531	10	1	18521	50	SLC4A4
2.668e-02	-3.62	HCO3_transpt_euk	interpro domains	IPR003020	10	1	18521	50	SLC4A4
2.668e-02	-3.62	MIR_motif	interpro domains	IPR016093	10	1	18521	50	RYR3
2.668e-02	-3.62	MIR_dom_sf	interpro domains	IPR036300	10	1	18521	50	RYR3
2.680e-02	-3.62	ZFHX3 (zinc finger homeobox 3)	protein interactions	463	99	2	19454	50	SOX5,TRPS1
2.683e-02	-3.62	ATPase-coupled transmembrane transporter activity	molecular function	GO:0042626	96	2	18094	48	ATP1A2,ATP13A4
2.693e-02	-3.61	positive regulation of phosphorylation	biological process	GO:0042327	619	5	18204	50	SASH1,TNIK,ERBB4,TPD52L1,FGFR3
2.693e-02	-3.61	CRX (cone-rod homeobox)	protein interactions	1406	252	3	19454	50	TRPS1,SOX5,NFIA
2.693e-02	-3.61	NCK2 (NCK adaptor protein 2)	protein interactions	8440	252	3	19454	50	ERBB4,NHSL1,TNIK
2.710e-02	-3.61	Neuronal System	REACTOME pathways	R-HSA-112316	349	4	10285	34	GLUL,SLC1A2,CAMK2G,SLC1A3
2.714e-02	-3.61	establishment of centrosome localization	biological process	GO:0051660	10	1	18204	50	PARD3
2.714e-02	-3.61	mitochondrial fragmentation involved in apoptotic process	biological process	GO:0043653	10	1	18204	50	ERBB4
2.714e-02	-3.61	positive regulation of lipopolysaccharide-mediated signaling pathway	biological process	GO:0031666	10	1	18204	50	SASH1
2.714e-02	-3.61	action potential propagation	biological process	GO:0098870	10	1	18204	50	ATP1A2
2.714e-02	-3.61	neuronal action potential propagation	biological process	GO:0019227	10	1	18204	50	ATP1A2
2.714e-02	-3.61	regulation of mesenchymal stem cell differentiation	biological process	GO:2000739	10	1	18204	50	SOX5
2.714e-02	-3.61	release of sequestered calcium ion into cytosol by endoplasmic reticulum	biological process	GO:1903514	10	1	18204	50	RYR3
2.719e-02	-3.60	Tyr_kinase_AS	interpro domains	IPR008266	95	2	18521	50	ERBB4,FGFR3
2.719e-02	-3.60	response to organic cyclic compound	biological process	GO:0014070	843	6	18204	50	RORA,RYR3,SLC1A3,ATP1A2,PTGDS,SLC1A2
2.731e-02	-3.60	EDEM2 (ER degradation enhancing alpha-mannosidase like protein 2)	protein interactions	55741	100	2	19454	50	HPSE2,CLU
2.731e-02	-3.60	ATP4A (ATPase H+/K+ transporting subunit alpha)	protein interactions	495	100	2	19454	50	ATP1A2,GPM6A
2.756e-02	-3.59	muscle contraction	biological process	GO:0006936	238	3	18204	50	DTNA,ATP1A2,RYR3
2.775e-02	-3.58	HCO3_cotransp	pfam domains	PF00955	10	1	17795	50	SLC4A4
2.775e-02	-3.58	PAS_3	pfam domains	PF08447	10	1	17795	50	NPAS3
2.775e-02	-3.58	MIR	pfam domains	PF02815	10	1	17795	50	RYR3
2.776e-02	-3.58	DYNLL2 (dynein light chain LC8-type 2)	protein interactions	140735	255	3	19454	50	TRPS1,NFIA,NHSL1
2.781e-02	-3.58	ILKAP (ILK associated serine/threonine phosphatase)	protein interactions	80895	101	2	19454	50	ERBB4,FGFR3
2.781e-02	-3.58	CLEC4A (C-type lectin domain family 4 member A)	protein interactions	50856	101	2	19454	50	FGFR3,CTNNA2
2.792e-02	-3.58	CCDC17 (coiled-coil domain containing 17)	protein interactions	149483	11	1	19454	50	FGFR3
2.792e-02	-3.58	DAZ1 (deleted in azoospermia 1)	protein interactions	1617	11	1	19454	50	QKI
2.792e-02	-3.58	PTGDR (prostaglandin D2 receptor)	protein interactions	5729	11	1	19454	50	PTGDS
2.792e-02	-3.58	IL7 (interleukin 7)	protein interactions	3574	11	1	19454	50	QKI
2.792e-02	-3.58	SYN3 (synapsin III)	protein interactions	8224	11	1	19454	50	GPM6A
2.792e-02	-3.58	Gtf2e2 (general transcription factor II E, polypeptide 2 (beta subunit))	protein interactions	68153	11	1	19454	50	NHSL1
2.792e-02	-3.58	Cobll1 (Cobl-like 1)	protein interactions	319876	11	1	19454	50	ABLIM1
2.792e-02	-3.58	MSRB1 (methionine sulfoxide reductase B1)	protein interactions	51734	11	1	19454	50	CLU
2.792e-02	-3.58	AQP5 (aquaporin 5)	protein interactions	362	11	1	19454	50	ATP1A2
2.814e-02	-3.57	basolateral plasma membrane	cellular component	GO:0016323	257	3	19108	49	SLC4A4,ERBB4,CADM1
2.831e-02	-3.56	ankle	COSMIC cancer mutations	ankle	398	4	16828	49	PARD3,ATP13A4,ERBB4,PREX2
2.832e-02	-3.56	human chr8q12.3	chromosome location	human chr8q12.3	15	1	26134	50	NKAIN3
2.832e-02	-3.56	MIR7-1 (microRNA 7-1)	protein interactions	407043	102	2	19454	50	QKI,MSI2
2.842e-02	-3.56	SFN (stratifin)	protein interactions	2810	671	5	19454	50	TNIK,NFIA,PARD3,ABLIM1,SASH1
2.845e-02	-3.56	protein domain specific binding	molecular function	GO:0019904	651	5	18094	48	CADM1,QKI,TRPS1,DOCK4,DTNA
2.865e-02	-3.55	soft_tissue-striated_muscle-rhabdomyosarcoma	COSMIC cancer mutations	soft_tissue-striated_muscle-rhabdomyosarcoma	594	5	16828	49	TRPS1,DOCK4,PREX2,CTNND2,COL5A3
2.875e-02	-3.55	renal_cell_carcinoma_unclassified	COSMIC cancer mutations	renal_cell_carcinoma_unclassified	10	1	16828	49	FGFR3
2.875e-02	-3.55	cervical_intraepithelial_neoplasia_Grade_III	COSMIC cancer mutations	cervical_intraepithelial_neoplasia_Grade_III	10	1	16828	49	FGFR3
2.875e-02	-3.55	cervix-in_situ_neoplasm-cervical_intraepithelial_neoplasia_Grade_III	COSMIC cancer mutations	cervix-in_situ_neoplasm-cervical_intraepithelial_neoplasia_Grade_III	10	1	16828	49	FGFR3
2.875e-02	-3.55	skin-back-malignant_melanoma-nodular	COSMIC cancer mutations	skin-back-malignant_melanoma-nodular	10	1	16828	49	PREX2
2.875e-02	-3.55	lung-carcinoma-pleomorphic_carcinoma	COSMIC cancer mutations	lung-carcinoma-pleomorphic_carcinoma	10	1	16828	49	FGFR3
2.875e-02	-3.55	kidney-carcinoma-renal_cell_carcinoma_unclassified	COSMIC cancer mutations	kidney-carcinoma-renal_cell_carcinoma_unclassified	10	1	16828	49	FGFR3
2.875e-02	-3.55	intradermal	COSMIC cancer mutations	intradermal	10	1	16828	49	FGFR3
2.875e-02	-3.55	chiasm	COSMIC cancer mutations	chiasm	10	1	16828	49	QKI
2.879e-02	-3.55	FLOT1 (flotillin 1)	protein interactions	10211	453	4	19454	50	PARD3,DTNA,SOX5,ABLIM1
2.880e-02	-3.55	sulfur amino acid transmembrane transporter activity	molecular function	GO:0000099	11	1	18094	48	SLC1A2
2.892e-02	-3.54	Bile Acid Indirect Signalling Pathway	SMPDB pathways	SMP0086851	8	1	1369	5	FGFR3
2.894e-02	-3.54	Ig-like_dom	interpro domains	IPR007110	432	4	18521	50	LSAMP,CADM1,NTM,FGFR3
2.897e-02	-3.54	large_intestine-caecum-adenoma	COSMIC cancer mutations	large_intestine-caecum-adenoma	229	3	16828	49	HPSE2,CTNND2,ERBB4
2.917e-02	-3.53	CYSTATIN	prosite domains	PS00287	9	1	12186	40	CST3
2.917e-02	-3.53	positive regulation of JNK cascade	biological process	GO:0046330	97	2	18204	50	TPD52L1,TNIK
2.927e-02	-3.53	VHP	smart domains	SM00153	8	1	9717	36	ABLIM1
2.931e-02	-3.53	DOCK_C_lobe_A	interpro domains	IPR043161	11	1	18521	50	DOCK4
2.931e-02	-3.53	DOCKER_Lobe_B	interpro domains	IPR046770	11	1	18521	50	DOCK4
2.931e-02	-3.53	C2_DOCK-type_domain	interpro domains	IPR027007	11	1	18521	50	DOCK4
2.931e-02	-3.53	Fib_collagen_C	interpro domains	IPR000885	11	1	18521	50	COL5A3
2.931e-02	-3.53	GBD/FH3_dom	interpro domains	IPR014768	11	1	18521	50	DAAM2
2.931e-02	-3.53	DOCK_C_lobe_C	interpro domains	IPR043162	11	1	18521	50	DOCK4
2.931e-02	-3.53	DOCKER_Lobe_C	interpro domains	IPR046773	11	1	18521	50	DOCK4
2.931e-02	-3.53	DOCKER_dom	interpro domains	IPR027357	11	1	18521	50	DOCK4
2.931e-02	-3.53	DOCK	interpro domains	IPR026791	11	1	18521	50	DOCK4
2.931e-02	-3.53	DOCKER_Lobe_A	interpro domains	IPR046769	11	1	18521	50	DOCK4
2.931e-02	-3.53	Muscle contraction	REACTOME pathways	R-HSA-397014	204	3	10285	34	RYR3,CAMK2G,ATP1A2
2.931e-02	-3.53	Proteoglycans in cancer	KEGG pathways	hsa05205	203	3	7161	24	HPSE2,ERBB4,CAMK2G
2.931e-02	-3.53	Proteoglycans in cancer	KEGG pathways	ko05205	203	3	7161	24	HPSE2,ERBB4,CAMK2G
2.933e-02	-3.53	Helical hairpin bin	gene3d domains	1.10.287.570	10	1	14470	43	SLC4A4
2.936e-02	-3.53	HUNK (hormonally up-regulated Neu-associated kinase)	protein interactions	30811	104	2	19454	50	ABLIM1,CLU
2.937e-02	-3.53	Terminal pathway of complement	REACTOME pathways	R-HSA-166665	9	1	10285	34	CLU
2.946e-02	-3.52	LGR4 (leucine rich repeat containing G protein-coupled receptor 4)	protein interactions	55366	261	3	19454	50	ZNRF3,ATP1A2,DAAM2
2.978e-02	-3.51	Heparan sulfate degradation	KEGG pathways	M00078	9	1	7161	24	HPSE2
2.978e-02	-3.51	Heparan sulfate degradation	KEGG pathways	hsa_M00078	9	1	7161	24	HPSE2
2.981e-02	-3.51	polyamine transport	biological process	GO:0015846	11	1	18204	50	ATP13A4
2.981e-02	-3.51	cellular response to caffeine	biological process	GO:0071313	11	1	18204	50	RYR3
2.981e-02	-3.51	lactone metabolic process	biological process	GO:1901334	11	1	18204	50	ATP1A2
2.981e-02	-3.51	L-ascorbic acid metabolic process	biological process	GO:0019852	11	1	18204	50	ATP1A2
2.981e-02	-3.51	intracellular mRNA localization	biological process	GO:0008298	11	1	18204	50	QKI
2.981e-02	-3.51	establishment or maintenance of transmembrane electrochemical gradient	biological process	GO:0010248	11	1	18204	50	ATP1A2
2.984e-02	-3.51	cell motility	biological process	GO:0048870	1101	7	18204	50	CDH20,DAAM2,GPC5,ERBB4,GPM6A,DOCK4,CTNNA2
2.988e-02	-3.51	IRF2BP2 (interferon regulatory factor 2 binding protein 2)	protein interactions	359948	105	2	19454	50	NFIA,ERBB4
2.988e-02	-3.51	BEND3 (BEN domain containing 3)	protein interactions	57673	105	2	19454	50	TNIK,TRPS1
2.988e-02	-3.51	ANP32E (acidic nuclear phosphoprotein 32 family member E)	protein interactions	81611	105	2	19454	50	PARD3,AHCYL2
3.022e-02	-3.50	HCO3TRNSPORT	prints domains	PR01231	10	1	5227	16	SLC4A4
3.035e-02	-3.49	fibrillar collagen trimer	cellular component	GO:0005583	12	1	19108	49	COL5A3
3.035e-02	-3.49	sodium:potassium-exchanging ATPase complex	cellular component	GO:0005890	12	1	19108	49	ATP1A2
3.035e-02	-3.49	banded collagen fibril	cellular component	GO:0098643	12	1	19108	49	COL5A3
3.039e-02	-3.49	skin-hand-carcinoma-squamous_cell_carcinoma	COSMIC cancer mutations	skin-hand-carcinoma-squamous_cell_carcinoma	407	4	16828	49	ERBB4,FGFR3,SLC4A4,COL5A3
3.040e-02	-3.49	USP30 (ubiquitin specific peptidase 30)	protein interactions	84749	106	2	19454	50	FGFR3,QKI
3.042e-02	-3.49	MMP25 (matrix metallopeptidase 25)	protein interactions	64386	12	1	19454	50	CLU
3.042e-02	-3.49	LGR5 (leucine rich repeat containing G protein-coupled receptor 5)	protein interactions	8549	12	1	19454	50	ZNRF3
3.042e-02	-3.49	TREM2 (triggering receptor expressed on myeloid cells 2)	protein interactions	54209	12	1	19454	50	CLU
3.042e-02	-3.49	PTPN20 (protein tyrosine phosphatase non-receptor type 20)	protein interactions	26095	12	1	19454	50	ERBB4
3.042e-02	-3.49	CA4 (carbonic anhydrase 4)	protein interactions	762	12	1	19454	50	SLC4A4
3.042e-02	-3.49	SMIM20 (small integral membrane protein 20)	protein interactions	389203	12	1	19454	50	ERBB4
3.042e-02	-3.49	OAS2 (2'-5'-oligoadenylate synthetase 2)	protein interactions	4939	12	1	19454	50	SASH1
3.042e-02	-3.49	ART4 (ADP-ribosyltransferase 4 (inactive) (Dombrock blood group))	protein interactions	420	12	1	19454	50	GPM6A
3.042e-02	-3.49	Pard6b (par-6 family cell polarity regulator beta)	protein interactions	58220	12	1	19454	50	PARD3
3.042e-02	-3.49	LMP-1 (latent membrane protein LMP-1)	protein interactions	3783750	12	1	19454	50	TNIK
3.049e-02	-3.49	DHR-2_Lobe_A	pfam domains	PF06920	11	1	17795	50	DOCK4
3.049e-02	-3.49	DHR-2_Lobe_B	pfam domains	PF20422	11	1	17795	50	DOCK4
3.049e-02	-3.49	DOCK-C2	pfam domains	PF14429	11	1	17795	50	DOCK4
3.049e-02	-3.49	COLFI	pfam domains	PF01410	11	1	17795	50	COL5A3
3.049e-02	-3.49	DHR-2_Lobe_C	pfam domains	PF20421	11	1	17795	50	DOCK4
3.079e-02	-3.48	inorganic ion homeostasis	biological process	GO:0098771	433	4	18204	50	ATP1A2,SLC1A3,RYR3,ATP13A4
3.093e-02	-3.48	regulation of muscle system process	biological process	GO:0090257	249	3	18204	50	ATP1A2,DOCK4,CAMK2G
3.107e-02	-3.47	MCAM (melanoma cell adhesion molecule)	protein interactions	4162	464	4	19454	50	DAAM2,CTNNA2,SASH1,TNIK
3.147e-02	-3.46	BIN1 (bridging integrator 1)	protein interactions	274	108	2	19454	50	CLU,GPM6A
3.147e-02	-3.46	CAMKV (CaM kinase like vesicle associated)	protein interactions	79012	108	2	19454	50	AHCYL2,GPM6A
3.147e-02	-3.46	PAX8 (paired box 8)	protein interactions	7849	108	2	19454	50	NFIA,TRPS1
3.149e-02	-3.46	PFN1 (profilin 1)	protein interactions	5216	466	4	19454	50	CAMK2G,ABLIM1,NHSL1,DOCK4
3.157e-02	-3.46	calcium ion transport	biological process	GO:0006816	251	3	18204	50	GPM6A,TRPM3,RYR3
3.158e-02	-3.46	skin-hand-malignant_melanoma-acral_lentiginous	COSMIC cancer mutations	skin-hand-malignant_melanoma-acral_lentiginous	11	1	16828	49	PREX2
3.158e-02	-3.46	pleomorphic_carcinoma	COSMIC cancer mutations	pleomorphic_carcinoma	11	1	16828	49	FGFR3
3.158e-02	-3.46	prostate-hyperplasia	COSMIC cancer mutations	prostate-hyperplasia	11	1	16828	49	FGFR3
3.158e-02	-3.46	skin-scalp-carcinoma-basal_cell_carcinoma	COSMIC cancer mutations	skin-scalp-carcinoma-basal_cell_carcinoma	11	1	16828	49	FGFR3
3.158e-02	-3.46	congenital	COSMIC cancer mutations	congenital	11	1	16828	49	FGFR3
3.158e-02	-3.46	oncocytoma	COSMIC cancer mutations	oncocytoma	11	1	16828	49	FGFR3
3.158e-02	-3.46	skin-neck-carcinoma-basal_cell_carcinoma	COSMIC cancer mutations	skin-neck-carcinoma-basal_cell_carcinoma	11	1	16828	49	FGFR3
3.158e-02	-3.46	seborrhoeic_keratosis	COSMIC cancer mutations	seborrhoeic_keratosis	11	1	16828	49	FGFR3
3.158e-02	-3.46	kidney-other-oncocytoma	COSMIC cancer mutations	kidney-other-oncocytoma	11	1	16828	49	FGFR3
3.158e-02	-3.46	skin-back-malignant_melanoma-superficial_spreading	COSMIC cancer mutations	skin-back-malignant_melanoma-superficial_spreading	11	1	16828	49	PREX2
3.167e-02	-3.45	skin-trunk-malignant_melanoma-nodular	COSMIC cancer mutations	skin-trunk-malignant_melanoma-nodular	1291	8	16828	49	NPAS3,PREX2,CTNND2,ABLIM1,CDH20,ATP1A2,ATP13A4,ERBB4
3.177e-02	-3.45	EV release from cardiac cells and their functional effects	WikiPathways	WP3297	9	1	5310	19	ERBB4
3.193e-02	-3.44	MAD_homology1_Dwarfin-type	interpro domains	IPR003619	12	1	18521	50	NFIA
3.193e-02	-3.44	Lipocalin	interpro domains	IPR002345	12	1	18521	50	PTGDS
3.193e-02	-3.44	Lipocalin_CS	interpro domains	IPR022272	12	1	18521	50	PTGDS
3.197e-02	-3.44	Rap1 signaling pathway	KEGG pathways	ko04015	210	3	7161	24	FGFR3,DOCK4,PARD3
3.197e-02	-3.44	Rap1 signaling pathway	KEGG pathways	hsa04015	210	3	7161	24	PARD3,FGFR3,DOCK4
3.200e-02	-3.44	MIR34B (microRNA 34b)	protein interactions	407041	109	2	19454	50	QKI,MSI2
3.200e-02	-3.44	PRR20A (proline rich 20A)	protein interactions	122183	109	2	19454	50	TRPM3,SOX5
3.213e-02	-3.44	ATXN1 (ataxin 1)	protein interactions	6310	469	4	19454	50	NFIA,PTGDS,CST3,QKI
3.222e-02	-3.44	-	gene3d domains	1.25.40.410	11	1	14470	43	DOCK4
3.222e-02	-3.44	-	gene3d domains	1.20.58.740	11	1	14470	43	DOCK4
3.236e-02	-3.43	MIR	prosite domains	PS50919	10	1	12186	40	RYR3
3.236e-02	-3.43	Diseases of signal transduction	REACTOME pathways	R-HSA-5663202	369	4	10285	34	MAML2,QKI,ERBB4,FGFR3
3.245e-02	-3.43	Insulin secretion	KEGG pathways	hsa04911	85	2	7161	24	ATP1A2,CAMK2G
3.245e-02	-3.43	ErbB signaling pathway	KEGG pathways	ko04012	85	2	7161	24	CAMK2G,ERBB4
3.245e-02	-3.43	ErbB signaling pathway	KEGG pathways	hsa04012	85	2	7161	24	ERBB4,CAMK2G
3.248e-02	-3.43	negative regulation of vasoconstriction	biological process	GO:0045906	12	1	18204	50	DOCK4
3.248e-02	-3.43	negative regulation of collagen metabolic process	biological process	GO:0010713	12	1	18204	50	CST3
3.248e-02	-3.43	negative regulation of smooth muscle contraction	biological process	GO:0045986	12	1	18204	50	DOCK4
3.248e-02	-3.43	auditory behavior	biological process	GO:0031223	12	1	18204	50	SLC1A3
3.248e-02	-3.43	regulation of blood vessel remodeling	biological process	GO:0060312	12	1	18204	50	CST3
3.248e-02	-3.43	sulfur amino acid transport	biological process	GO:0000101	12	1	18204	50	SLC1A2
3.248e-02	-3.43	microglia differentiation	biological process	GO:0014004	12	1	18204	50	QKI
3.258e-02	-3.42	PI3K events in ERBB4 signaling	REACTOME pathways	R-HSA-1250342	10	1	10285	34	ERBB4
3.258e-02	-3.42	Signaling by FGFR3 fusions in cancer	REACTOME pathways	R-HSA-8853334	10	1	10285	34	FGFR3
3.258e-02	-3.42	Organic anion transporters	REACTOME pathways	R-HSA-428643	10	1	10285	34	SLC25A18
3.276e-02	-3.42	steroid binding	molecular function	GO:0005496	107	2	18094	48	ATP1A2,RORA
3.287e-02	-3.42	Drf_GBD	smart domains	SM01140	9	1	9717	36	DAAM2
3.287e-02	-3.42	Drf_FH3	smart domains	SM01139	9	1	9717	36	DAAM2
3.291e-02	-3.41	PLPPR4 (phospholipid phosphatase related 4)	protein interactions	9890	13	1	19454	50	ZNRF3
3.291e-02	-3.41	JAM2 (junctional adhesion molecule 2)	protein interactions	58494	13	1	19454	50	PARD3
3.291e-02	-3.41	NPR2 (natriuretic peptide receptor 2)	protein interactions	4882	13	1	19454	50	CAMK2G
3.291e-02	-3.41	RAB3C (RAB3C, member RAS oncogene family)	protein interactions	115827	13	1	19454	50	GPM6A
3.291e-02	-3.41	Rbm47 (RNA binding motif protein 47)	protein interactions	245945	13	1	19454	50	QKI
3.291e-02	-3.41	PCDHA2 (protocadherin alpha 2)	protein interactions	56146	13	1	19454	50	NFIA
3.291e-02	-3.41	TBCC (tubulin folding cofactor C)	protein interactions	6903	13	1	19454	50	NTM
3.303e-02	-3.41	Methionine degradation	KEGG pathways	hsa_M00035	10	1	7161	24	AHCYL2
3.303e-02	-3.41	Methionine degradation	KEGG pathways	M00035	10	1	7161	24	AHCYL2
3.318e-02	-3.41	protein complex oligomerization	biological process	GO:0051259	256	3	18204	50	TRPM3,RYR3,SLC1A2
3.321e-02	-3.40	MH1	pfam domains	PF03165	12	1	17795	50	NFIA
3.331e-02	-3.40	PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling	REACTOME pathways	R-HSA-6811558	87	2	10285	34	ERBB4,FGFR3
3.351e-02	-3.40	cell fate commitment	biological process	GO:0045165	257	3	18204	50	NFIA,SOX5,ERBB4
3.363e-02	-3.39	TSC22D4 (TSC22 domain family member 4)	protein interactions	81628	112	2	19454	50	ABLIM1,CLU
3.363e-02	-3.39	EDA (ectodysplasin A)	protein interactions	1896	112	2	19454	50	ERBB4,GPM6A
3.389e-02	-3.38	human chr18q21.33	chromosome location	human chr18q21.33	18	1	26134	50	CDH20
3.395e-02	-3.38	potassium ion binding	molecular function	GO:0030955	13	1	18094	48	ATP1A2
3.395e-02	-3.38	monoatomic cation:bicarbonate symporter activity	molecular function	GO:0140410	13	1	18094	48	SLC4A4
3.401e-02	-3.38	Cell junction organization	REACTOME pathways	R-HSA-446728	88	2	10285	34	PARD3,CADM1
3.418e-02	-3.38	GFI1B (growth factor independent 1B transcriptional repressor)	protein interactions	8328	113	2	19454	50	ZNRF3,DTNA
3.418e-02	-3.38	ARHGAP36 (Rho GTPase activating protein 36)	protein interactions	158763	113	2	19454	50	CLU,DOCK4
3.432e-02	-3.37	PROTEIN_KINASE_ATP	prosite domains	PS00107	377	4	12186	40	TNIK,ERBB4,CAMK2G,FGFR3
3.440e-02	-3.37	cervix-carcinoma-mixed_adenosquamous_carcinoma	COSMIC cancer mutations	cervix-carcinoma-mixed_adenosquamous_carcinoma	12	1	16828	49	FGFR3
3.440e-02	-3.37	skin-benign_melanocytic_nevus	COSMIC cancer mutations	skin-benign_melanocytic_nevus	12	1	16828	49	FGFR3
3.440e-02	-3.37	skin-abdomen-malignant_melanoma-nodular	COSMIC cancer mutations	skin-abdomen-malignant_melanoma-nodular	12	1	16828	49	PREX2
3.440e-02	-3.37	central_nervous_system-fourth_ventricle-glioma-astrocytoma_Grade_I	COSMIC cancer mutations	central_nervous_system-fourth_ventricle-glioma-astrocytoma_Grade_I	12	1	16828	49	QKI
3.440e-02	-3.37	skin-face-carcinoma-basal_cell_carcinoma	COSMIC cancer mutations	skin-face-carcinoma-basal_cell_carcinoma	12	1	16828	49	FGFR3
3.500e-02	-3.35	Ion_trans_dom	interpro domains	IPR005821	109	2	18521	50	RYR3,TRPM3
3.510e-02	-3.35	-	gene3d domains	3.10.450.50	12	1	14470	43	CAMK2G
3.510e-02	-3.35	Alpha-catenin/vinculin-like	gene3d domains	1.20.120.230	12	1	14470	43	CTNNA2
3.514e-02	-3.35	olfactory bulb interneuron differentiation	biological process	GO:0021889	13	1	18204	50	ERBB4
3.514e-02	-3.35	cerebellar Purkinje cell differentiation	biological process	GO:0021702	13	1	18204	50	RORA
3.514e-02	-3.35	T-helper 17 cell differentiation	biological process	GO:0072539	13	1	18204	50	RORA
3.514e-02	-3.35	negative regulation of cytosolic calcium ion concentration	biological process	GO:0051481	13	1	18204	50	ATP1A2
3.514e-02	-3.35	prepulse inhibition	biological process	GO:0060134	13	1	18204	50	CTNNA2
3.514e-02	-3.35	negative regulation of amyloid fibril formation	biological process	GO:1905907	13	1	18204	50	CLU
3.514e-02	-3.35	glial cell fate commitment	biological process	GO:0021781	13	1	18204	50	NFIA
3.514e-02	-3.35	regulation of respiratory gaseous exchange by nervous system process	biological process	GO:0002087	13	1	18204	50	ATP1A2
3.520e-02	-3.35	TYRKINASE	prints domains	PR00109	98	2	5227	16	ERBB4,FGFR3
3.520e-02	-3.35	TyrKc	smart domains	SM00219	80	2	9717	36	ERBB4,FGFR3
3.530e-02	-3.34	SMAD7 (SMAD family member 7)	protein interactions	4092	115	2	19454	50	PARD3,SOX5
3.530e-02	-3.34	TBXT (T-box transcription factor T)	protein interactions	6862	115	2	19454	50	NFIA,TRPS1
3.530e-02	-3.34	CDH2 (cadherin 2)	protein interactions	1000	115	2	19454	50	CTNND2,PARD3
3.531e-02	-3.34	Protein digestion and absorption	KEGG pathways	ko04974	89	2	7161	24	COL5A3,ATP1A2
3.531e-02	-3.34	Protein digestion and absorption	KEGG pathways	hsa04974	89	2	7161	24	COL5A3,ATP1A2
3.532e-02	-3.34	chromaffin granule	cellular component	GO:0042583	14	1	19108	49	CLU
3.533e-02	-3.34	regulation of plasma membrane bounded cell projection organization	biological process	GO:0120035	666	5	18204	50	GPM6A,CTNNA2,CAMK2G,DAAM2,TNIK
3.540e-02	-3.34	VSX2 (visual system homeobox 2)	protein interactions	338917	14	1	19454	50	AHCYL2
3.540e-02	-3.34	C9 (complement C9)	protein interactions	735	14	1	19454	50	CLU
3.540e-02	-3.34	TPSAB1 (tryptase alpha/beta 1)	protein interactions	7177	14	1	19454	50	CAMK2G
3.540e-02	-3.34	Stag2 (STAG2 cohesin complex component)	protein interactions	20843	14	1	19454	50	CLU
3.540e-02	-3.34	SLC1A2 (solute carrier family 1 member 2)	protein interactions	6506	14	1	19454	50	SLC1A2
3.540e-02	-3.34	RSPO1 (R-spondin 1)	protein interactions	284654	14	1	19454	50	ZNRF3
3.540e-02	-3.34	AZIN2 (antizyme inhibitor 2)	protein interactions	113451	14	1	19454	50	TPD52L1
3.540e-02	-3.34	CTSO (cathepsin O)	protein interactions	1519	14	1	19454	50	CST3
3.540e-02	-3.34	FGF7 (fibroblast growth factor 7)	protein interactions	2252	14	1	19454	50	FGFR3
3.540e-02	-3.34	CHAT (choline O-acetyltransferase)	protein interactions	1103	14	1	19454	50	CAMK2G
3.540e-02	-3.34	Aifm1 (apoptosis-inducing factor, mitochondrion-associated 1)	protein interactions	26926	14	1	19454	50	CLU
3.540e-02	-3.34	MB (myoglobin)	protein interactions	4151	14	1	19454	50	MAML2
3.544e-02	-3.34	PI3K/AKT Signaling in Cancer	REACTOME pathways	R-HSA-2219528	90	2	10285	34	ERBB4,FGFR3
3.553e-02	-3.34	lung-carcinoma-adenocarcinoma	COSMIC cancer mutations	lung-carcinoma-adenocarcinoma	15133	48	16828	49	CLU,DOCK4,CDH20,ERBB4,QKI,AHCYL2,HPSE2,SASH1,DAAM2,SLC25A18,PITPNC1,NFIA,TRPM3,COL5A3,GPC5,SOX5,ATP13A4,ATP1A2,PREX2,MAML2,FBXL7,GPM6A,SLC1A2,SLC4A4,TNIK,PTGDS,GLUL,ZNRF3,TRPS1,LSAMP,ABLIM1,CTNND2,PARD3,NKAIN3,DTNA,FGFR3,SLC1A3,NDRG2,NHSL1,NPAS3,NTM,TPD52L1,RYR3,MSI2,RORA,CADM1,ZBTB20,CAMK2G
3.553e-02	-3.34	GBD_FH3	prosite domains	PS51232	11	1	12186	40	DAAM2
3.553e-02	-3.34	C2_DOCK	prosite domains	PS51650	11	1	12186	40	DOCK4
3.553e-02	-3.34	GATA_ZN_FINGER_2	prosite domains	PS50114	11	1	12186	40	TRPS1
3.553e-02	-3.34	LIPOCALIN	prosite domains	PS00213	11	1	12186	40	PTGDS
3.553e-02	-3.34	NC1_FIB	prosite domains	PS51461	11	1	12186	40	COL5A3
3.553e-02	-3.34	DOCKER	prosite domains	PS51651	11	1	12186	40	DOCK4
3.561e-02	-3.34	regulation of protein metabolic process	biological process	GO:0051246	2218	11	18204	50	CST3,PARD3,MSI2,SASH1,TPD52L1,FGFR3,QKI,TNIK,ERBB4,CLU,CADM1
3.569e-02	-3.33	DYNLL1 (dynein light chain LC8-type 1)	protein interactions	8655	485	4	19454	50	CAMK2G,TRPS1,PARD3,GLUL
3.569e-02	-3.33	Circadian rythm related genes	WikiPathways	WP3594	207	3	5310	19	CST3,RORA,PTGDS
3.574e-02	-3.33	human chr11q25	chromosome location	human chr11q25	19	1	26134	50	NTM
3.574e-02	-3.33	human chr6q24.1	chromosome location	human chr6q24.1	19	1	26134	50	NHSL1
3.574e-02	-3.33	human chr5p15.2	chromosome location	human chr5p15.2	19	1	26134	50	CTNND2
3.576e-02	-3.33	LAMTOR1 (late endosomal/lysosomal adaptor, MAPK and MTOR activator 1)	protein interactions	55004	714	5	19454	50	TPD52L1,DTNA,TNIK,SLC1A3,PARD3
3.586e-02	-3.33	RBBP8 (RB binding protein 8, endonuclease)	protein interactions	5932	116	2	19454	50	CLU,CTNNA2
3.586e-02	-3.33	SKIL (SKI like proto-oncogene)	protein interactions	6498	116	2	19454	50	GLUL,SASH1
3.603e-02	-3.32	stomach-adenocarcinoma	COSMIC cancer mutations	stomach-adenocarcinoma	4101	18	16828	49	ATP13A4,QKI,ERBB4,TRPS1,AHCYL2,ATP1A2,CTNND2,ABLIM1,RORA,SASH1,PREX2,PARD3,SLC4A4,SLC1A2,CDH20,COL5A3,FGFR3,GPC5
3.612e-02	-3.32	chromophobe_renal_cell_carcinoma	COSMIC cancer mutations	chromophobe_renal_cell_carcinoma	430	4	16828	49	ERBB4,FGFR3,TNIK,CAMK2G
3.612e-02	-3.32	kidney-carcinoma-chromophobe_renal_cell_carcinoma	COSMIC cancer mutations	kidney-carcinoma-chromophobe_renal_cell_carcinoma	430	4	16828	49	TNIK,CAMK2G,FGFR3,ERBB4
3.612e-02	-3.32	long-chain fatty acid metabolic process	biological process	GO:0001676	109	2	18204	50	QKI,PTGDS
3.612e-02	-3.32	positive regulation of tumor necrosis factor production	biological process	GO:0032760	109	2	18204	50	CLU,ZBTB20
3.617e-02	-3.32	small_intestine	COSMIC cancer mutations	small_intestine	250	3	16828	49	ZNRF3,FGFR3,TNIK
3.623e-02	-3.32	regulation of cellular process	biological process	GO:0050794	11468	38	18204	50	CST3,DOCK4,TRPS1,ZNRF3,CLU,TNIK,ERBB4,NPAS3,RORA,PARD3,DAAM2,CTNNA2,QKI,TPD52L1,FGFR3,NFIA,GPM6A,SLC1A2,SOX5,PTGDS,CADM1,PITPNC1,RYR3,GPC5,SLC4A4,PREX2,MAML2,HPSE2,MSI2,ZBTB20,CAMK2G,SASH1,CTNND2,NDRG2,DTNA,GLUL,ATP1A2,SLC1A3
3.630e-02	-3.32	positive regulation of biological process	biological process	GO:0048518	6326	24	18204	50	SLC1A3,ATP1A2,ZBTB20,SASH1,HPSE2,SLC4A4,MAML2,CADM1,GPC5,SLC1A2,SOX5,NFIA,GPM6A,QKI,FGFR3,TPD52L1,RORA,DAAM2,PARD3,NPAS3,ERBB4,CLU,TNIK,DOCK4
3.631e-02	-3.32	neuronal cell body	cellular component	GO:0043025	489	4	19108	49	CTNND2,SLC1A3,ATP1A2,GPM6A
3.642e-02	-3.31	ELK3 (ETS transcription factor ELK3)	protein interactions	2004	117	2	19454	50	TRPS1,NFIA
3.645e-02	-3.31	MIR	smart domains	SM00472	10	1	9717	36	RYR3
3.646e-02	-3.31	skin-scalp-malignant_melanoma	COSMIC cancer mutations	skin-scalp-malignant_melanoma	634	5	16828	49	PREX2,CAMK2G,NTM,ERBB4,NFIA
3.647e-02	-3.31	Dppa3 (developmental pluripotency-associated 3)	protein interactions	73708	284	3	19454	50	CAMK2G,ATP1A2,MSI2
3.661e-02	-3.31	SNX27 (sorting nexin 27)	protein interactions	81609	489	4	19454	50	COL5A3,CLU,ABLIM1,SLC1A3
3.668e-02	-3.31	CAV1 (caveolin 1)	protein interactions	857	719	5	19454	50	AHCYL2,DTNA,PARD3,SLC1A3,TNIK
3.672e-02	-3.30	positive regulation of canonical Wnt signaling pathway	biological process	GO:0090263	110	2	18204	50	GPC5,DAAM2
3.688e-02	-3.30	plasma membrane bounded cell projection organization	biological process	GO:0120036	1152	7	18204	50	TNIK,CTNNA2,CTNND2,PARD3,ABLIM1,PREX2,GPM6A
3.689e-02	-3.30	Post-translational modification: synthesis of GPI-anchored proteins	REACTOME pathways	R-HSA-163125	92	2	10285	34	LSAMP,NTM
3.695e-02	-3.30	small molecule biosynthetic process	biological process	GO:0044283	459	4	18204	50	PTGDS,QKI,GLUL,SLC1A3
3.699e-02	-3.30	PLCD3 (phospholipase C delta 3)	protein interactions	113026	118	2	19454	50	TNIK,AHCYL2
3.715e-02	-3.29	Neurexin-like	interpro domains	IPR003585	14	1	18521	50	CADM1
3.721e-02	-3.29	Brenner_tumour	COSMIC cancer mutations	Brenner_tumour	13	1	16828	49	FGFR3
3.721e-02	-3.29	cervix-carcinoma-adenocarcinoma	COSMIC cancer mutations	cervix-carcinoma-adenocarcinoma	13	1	16828	49	FGFR3
3.721e-02	-3.29	skin-shoulder-malignant_melanoma-nodular	COSMIC cancer mutations	skin-shoulder-malignant_melanoma-nodular	13	1	16828	49	PREX2
3.721e-02	-3.29	skin-back-carcinoma-basal_cell_carcinoma	COSMIC cancer mutations	skin-back-carcinoma-basal_cell_carcinoma	13	1	16828	49	FGFR3
3.721e-02	-3.29	skin-scalp-malignant_melanoma-nodular	COSMIC cancer mutations	skin-scalp-malignant_melanoma-nodular	13	1	16828	49	PREX2
3.721e-02	-3.29	endometrium-ovary-endometriosis	COSMIC cancer mutations	endometrium-ovary-endometriosis	13	1	16828	49	FGFR3
3.721e-02	-3.29	central_nervous_system-hypothalamus-glioma-astrocytoma_Grade_I	COSMIC cancer mutations	central_nervous_system-hypothalamus-glioma-astrocytoma_Grade_I	13	1	16828	49	QKI
3.724e-02	-3.29	regulation of signal transduction	biological process	GO:0009966	3114	14	18204	50	GPC5,CADM1,TNIK,ERBB4,CLU,ZNRF3,CTNND2,SASH1,NDRG2,TPD52L1,FGFR3,PREX2,DAAM2,RORA
3.729e-02	-3.29	soft_tissue-striated_muscle-rhabdomyosarcoma-embryonal	COSMIC cancer mutations	soft_tissue-striated_muscle-rhabdomyosarcoma-embryonal	2659	13	16828	49	RYR3,ZNRF3,CTNND2,RORA,CAMK2G,PREX2,MAML2,NFIA,TRPM3,DOCK4,COL5A3,FGFR3,NPAS3
3.729e-02	-3.29	embryonal	COSMIC cancer mutations	embryonal	2659	13	16828	49	CTNND2,RORA,CAMK2G,PREX2,MAML2,RYR3,ZNRF3,COL5A3,FGFR3,NPAS3,NFIA,TRPM3,DOCK4
3.759e-02	-3.28	human chr8p21.1	chromosome location	human chr8p21.1	20	1	26134	50	CLU
3.764e-02	-3.28	Ion_trans	pfam domains	PF00520	109	2	17795	50	TRPM3,RYR3
3.779e-02	-3.28	NEDD4 (NEDD4 E3 ubiquitin protein ligase)	protein interactions	4734	494	4	19454	50	FGFR3,MAML2,ERBB4,TNIK
3.779e-02	-3.28	relaxation of cardiac muscle	biological process	GO:0055119	14	1	18204	50	ATP1A2
3.779e-02	-3.28	glutathione biosynthetic process	biological process	GO:0006750	14	1	18204	50	SLC1A2
3.779e-02	-3.28	cellular response to purine-containing compound	biological process	GO:0071415	14	1	18204	50	RYR3
3.779e-02	-3.28	regulation of protein K63-linked ubiquitination	biological process	GO:1900044	14	1	18204	50	SASH1
3.779e-02	-3.28	mechanosensory behavior	biological process	GO:0007638	14	1	18204	50	SLC1A3
3.779e-02	-3.28	negative regulation of oligodendrocyte differentiation	biological process	GO:0048715	14	1	18204	50	DAAM2
3.779e-02	-3.28	neurotransmitter receptor localization to postsynaptic specialization membrane	biological process	GO:0099645	14	1	18204	50	ERBB4
3.779e-02	-3.28	protein localization to postsynaptic specialization membrane	biological process	GO:0099633	14	1	18204	50	ERBB4
3.779e-02	-3.28	negative regulation of sodium ion transmembrane transporter activity	biological process	GO:2000650	14	1	18204	50	ATP1A2
3.779e-02	-3.28	regulation of skeletal muscle adaptation	biological process	GO:0014733	14	1	18204	50	CAMK2G
3.780e-02	-3.28	axolemma	cellular component	GO:0030673	15	1	19108	49	SLC1A2
3.788e-02	-3.27	FGF9 (fibroblast growth factor 9)	protein interactions	2254	15	1	19454	50	FGFR3
3.788e-02	-3.27	RNASE13 (ribonuclease A family member 13 (inactive))	protein interactions	440163	15	1	19454	50	CLU
3.794e-02	-3.27	regulation of gliogenesis	biological process	GO:0014013	112	2	18204	50	DAAM2,QKI
3.799e-02	-3.27	PROTEIN_KINASE_TYR	prosite domains	PS00109	94	2	12186	40	ERBB4,FGFR3
3.802e-02	-3.27	OCLN (occludin)	protein interactions	100506658	495	4	19454	50	TNIK,PARD3,ABLIM1,DTNA
3.814e-02	-3.27	HOXB9 (homeobox B9)	protein interactions	3219	120	2	19454	50	AHCYL2,NFIA
3.837e-02	-3.26	Negative regulation of the PI3K/AKT network	REACTOME pathways	R-HSA-199418	94	2	10285	34	FGFR3,ERBB4
3.843e-02	-3.26	SREBF2 (sterol regulatory element binding transcription factor 2)	protein interactions	6721	290	3	19454	50	SLC4A4,GLUL,ABLIM1
3.851e-02	-3.26	stomach-carcinoma	COSMIC cancer mutations	stomach-carcinoma	439	4	16828	49	FGFR3,ERBB4,CAMK2G,TNIK
3.856e-02	-3.26	positive regulation of tumor necrosis factor superfamily cytokine production	biological process	GO:1903557	113	2	18204	50	CLU,ZBTB20
3.857e-02	-3.26	extracellular region	cellular component	GO:0005576	4350	17	19108	49	GPC5,FGFR3,LSAMP,CST3,SLC4A4,DAAM2,COL5A3,ERBB4,NTM,GPM6A,NDRG2,CLU,GLUL,TNIK,PTGDS,HPSE2,ATP1A2
3.864e-02	-3.25	GATA	pfam domains	PF00320	14	1	17795	50	TRPS1
3.872e-02	-3.25	MED15 (mediator complex subunit 15)	protein interactions	51586	121	2	19454	50	QKI,NFIA
3.873e-02	-3.25	regulation of cell projection organization	biological process	GO:0031344	683	5	18204	50	DAAM2,TNIK,GPM6A,CAMK2G,CTNNA2
3.876e-02	-3.25	GOPC (golgi associated PDZ and coiled-coil motif containing)	protein interactions	57120	291	3	19454	50	SLC25A18,TPD52L1,FGFR3
3.898e-02	-3.24	Signaling by activated point mutants of FGFR3	REACTOME pathways	R-HSA-1839130	12	1	10285	34	FGFR3
3.898e-02	-3.24	FGFR3 mutant receptor activation	REACTOME pathways	R-HSA-2033514	12	1	10285	34	FGFR3
3.898e-02	-3.24	Defective EXT1 causes exostoses 1, TRPS2 and CHDS	REACTOME pathways	R-HSA-3656253	12	1	10285	34	GPC5
3.898e-02	-3.24	Defective EXT2 causes exostoses 2	REACTOME pathways	R-HSA-3656237	12	1	10285	34	GPC5
3.900e-02	-3.24	germ_cell_tumour	COSMIC cancer mutations	germ_cell_tumour	867	6	16828	49	FGFR3,ERBB4,TNIK,PREX2,CAMK2G,TRPS1
3.908e-02	-3.24	phosphatidylglycerol binding	molecular function	GO:1901611	15	1	18094	48	PITPNC1
3.908e-02	-3.24	C4-dicarboxylate transmembrane transporter activity	molecular function	GO:0015556	15	1	18094	48	SLC25A18
3.912e-02	-3.24	regulation of developmental process	biological process	GO:0050793	2540	12	18204	50	CST3,TRPS1,SOX5,ERBB4,TNIK,DAAM2,PARD3,RORA,SASH1,FGFR3,GLUL,QKI
3.918e-02	-3.24	regulation of circadian rhythm	biological process	GO:0042752	114	2	18204	50	RORA,PTGDS
3.930e-02	-3.24	BRK1 (BRICK1 subunit of SCAR/WAVE actin nucleating complex)	protein interactions	55845	122	2	19454	50	DTNA,NHSL1
3.930e-02	-3.24	SLMAP (sarcolemma associated protein)	protein interactions	7871	122	2	19454	50	CAMK2G,TNIK
3.935e-02	-3.24	perinuclear region of cytoplasm	cellular component	GO:0048471	735	5	19108	49	TPD52L1,CLU,SLC1A3,NDRG2,PTGDS
3.943e-02	-3.23	human chr13q31.3	chromosome location	human chr13q31.3	21	1	26134	50	GPC5
3.959e-02	-3.23	NAD+ Signalling and Aging	SMPDB pathways	SMP0084271	11	1	1369	5	RORA
3.963e-02	-3.23	lung-carcinoma-squamous_cell_carcinoma	COSMIC cancer mutations	lung-carcinoma-squamous_cell_carcinoma	14664	47	16828	49	DAAM2,SLC25A18,SASH1,AHCYL2,HPSE2,ERBB4,QKI,DOCK4,CDH20,CLU,MAML2,PREX2,GPM6A,FBXL7,ATP1A2,ATP13A4,SOX5,GPC5,COL5A3,TRPM3,NFIA,PITPNC1,ABLIM1,LSAMP,CTNND2,TRPS1,ZNRF3,TNIK,GLUL,PTGDS,SLC1A2,SLC4A4,ZBTB20,CADM1,CAMK2G,RORA,MSI2,TPD52L1,NTM,RYR3,SLC1A3,NHSL1,NPAS3,FGFR3,DTNA,NKAIN3,PARD3
3.975e-02	-3.23	Znf_GATA	interpro domains	IPR000679	15	1	18521	50	TRPS1
3.975e-02	-3.23	ATPase_P-typ_cation-transptr_C	interpro domains	IPR006068	15	1	18521	50	ATP1A2
3.975e-02	-3.23	NTF2-like_dom_sf	interpro domains	IPR032710	15	1	18521	50	CAMK2G
3.975e-02	-3.23	FH2_Formin	interpro domains	IPR015425	15	1	18521	50	DAAM2
3.975e-02	-3.23	CNH_dom	interpro domains	IPR001180	15	1	18521	50	TNIK
3.975e-02	-3.23	FH2_Formin_sf	interpro domains	IPR042201	15	1	18521	50	DAAM2
3.978e-02	-3.22	Pancreatic secretion	KEGG pathways	ko04972	95	2	7161	24	ATP1A2,SLC4A4
3.978e-02	-3.22	Pancreatic secretion	KEGG pathways	hsa04972	95	2	7161	24	SLC4A4,ATP1A2
3.981e-02	-3.22	fatty acid biosynthetic process	biological process	GO:0006633	115	2	18204	50	PTGDS,QKI
3.988e-02	-3.22	PAX7 (paired box 7)	protein interactions	5081	123	2	19454	50	TRPS1,NFIA
4.002e-02	-3.22	soft_tissue-small_round_cell_tumour	COSMIC cancer mutations	soft_tissue-small_round_cell_tumour	14	1	16828	49	FGFR3
4.002e-02	-3.22	small_round_cell_tumour	COSMIC cancer mutations	small_round_cell_tumour	14	1	16828	49	FGFR3
4.002e-02	-3.22	endometriosis	COSMIC cancer mutations	endometriosis	14	1	16828	49	FGFR3
4.002e-02	-3.22	in_situ_neoplasm	COSMIC cancer mutations	in_situ_neoplasm	14	1	16828	49	FGFR3
4.002e-02	-3.22	urinary_tract-renal_pelvis-carcinoma-transitional_cell_carcinoma	COSMIC cancer mutations	urinary_tract-renal_pelvis-carcinoma-transitional_cell_carcinoma	14	1	16828	49	FGFR3
4.003e-02	-3.22	COLFI	smart domains	SM00038	11	1	9717	36	COL5A3
4.008e-02	-3.22	telencephalon development	biological process	GO:0021537	276	3	18204	50	SLC1A2,ERBB4,ATP1A2
4.023e-02	-3.21	Prot_kinase_dom	interpro domains	IPR000719	480	4	18521	50	TNIK,ERBB4,CAMK2G,FGFR3
4.024e-02	-3.21	animal organ development	biological process	GO:0048513	2846	13	18204	50	NFIA,GPM6A,CADM1,ERBB4,COL5A3,SLC1A2,SOX5,RORA,ABLIM1,ATP1A2,FGFR3,CTNNA2,NDRG2
4.027e-02	-3.21	postsynaptic density, intracellular component	cellular component	GO:0099092	16	1	19108	49	TNIK
4.035e-02	-3.21	TWIST2 (twist family bHLH transcription factor 2)	protein interactions	117581	16	1	19454	50	ZBTB20
4.035e-02	-3.21	GALNT13 (polypeptide N-acetylgalactosaminyltransferase 13)	protein interactions	114805	16	1	19454	50	TNIK
4.035e-02	-3.21	CDH12 (cadherin 12)	protein interactions	1010	16	1	19454	50	CTNNA2
4.035e-02	-3.21	HLA-H (major histocompatibility complex, class I, H (pseudogene))	protein interactions	3136	16	1	19454	50	FGFR3
4.035e-02	-3.21	FZD4 (frizzled class receptor 4)	protein interactions	8322	16	1	19454	50	ZNRF3
4.035e-02	-3.21	TPD52L3 (TPD52 like 3)	protein interactions	89882	16	1	19454	50	TPD52L1
4.035e-02	-3.21	DUS1L (dihydrouridine synthase 1 like)	protein interactions	64118	16	1	19454	50	CAMK2G
4.035e-02	-3.21	SAPCD1 (suppressor APC domain containing 1)	protein interactions	401251	16	1	19454	50	CTNNA2
4.035e-02	-3.21	TMEM134 (transmembrane protein 134)	protein interactions	80194	16	1	19454	50	ERBB4
4.035e-02	-3.21	CAMK1G (calcium/calmodulin dependent protein kinase IG)	protein interactions	57172	16	1	19454	50	CAMK2G
4.035e-02	-3.21	CTSK (cathepsin K)	protein interactions	1513	16	1	19454	50	FGFR3
4.043e-02	-3.21	regulation of circadian sleep/wake cycle, sleep	biological process	GO:0045187	15	1	18204	50	PTGDS
4.043e-02	-3.21	synapse maturation	biological process	GO:0060074	15	1	18204	50	NFIA
4.043e-02	-3.21	neuroblast division	biological process	GO:0055057	15	1	18204	50	SOX5
4.043e-02	-3.21	response to caffeine	biological process	GO:0031000	15	1	18204	50	RYR3
4.043e-02	-3.21	chondrocyte proliferation	biological process	GO:0035988	15	1	18204	50	FGFR3
4.043e-02	-3.21	exit from mitosis	biological process	GO:0010458	15	1	18204	50	NFIA
4.043e-02	-3.21	protein homotrimerization	biological process	GO:0070207	15	1	18204	50	SLC1A2
4.043e-02	-3.21	sarcoplasmic reticulum calcium ion transport	biological process	GO:0070296	15	1	18204	50	RYR3
4.043e-02	-3.21	negative regulation of sodium ion transmembrane transport	biological process	GO:1902306	15	1	18204	50	ATP1A2
4.043e-02	-3.21	cerebellar Purkinje cell layer formation	biological process	GO:0021694	15	1	18204	50	RORA
4.043e-02	-3.21	intracellular potassium ion homeostasis	biological process	GO:0030007	15	1	18204	50	ATP1A2
4.054e-02	-3.21	Circadian entrainment	KEGG pathways	hsa04713	96	2	7161	24	CAMK2G,RYR3
4.054e-02	-3.21	Circadian entrainment	KEGG pathways	ko04713	96	2	7161	24	RYR3,CAMK2G
4.101e-02	-3.19	Ig-like_dom_sf	interpro domains	IPR036179	483	4	18521	50	FGFR3,NTM,CADM1,LSAMP
4.106e-02	-3.19	TCHP (trichoplein keratin filament binding)	protein interactions	84260	125	2	19454	50	GLUL,PARD3
4.134e-02	-3.19	FH2	pfam domains	PF02181	15	1	17795	50	DAAM2
4.134e-02	-3.19	CNH	pfam domains	PF00780	15	1	17795	50	TNIK
4.134e-02	-3.19	Cation_ATPase_C	pfam domains	PF00689	15	1	17795	50	ATP1A2
4.145e-02	-3.18	skin-acral-malignant_melanoma	COSMIC cancer mutations	skin-acral-malignant_melanoma	264	3	16828	49	COL5A3,PARD3,CDH20
4.158e-02	-3.18	SH3 domain binding	molecular function	GO:0017124	122	2	18094	48	DOCK4,QKI
4.163e-02	-3.18	mitogen-activated protein kinase kinase kinase binding	molecular function	GO:0031435	16	1	18094	48	SASH1
4.163e-02	-3.18	misfolded protein binding	molecular function	GO:0051787	16	1	18094	48	CLU
4.163e-02	-3.18	oxysterol binding	molecular function	GO:0008142	16	1	18094	48	RORA
4.166e-02	-3.18	SYP (synaptophysin)	protein interactions	6855	126	2	19454	50	PITPNC1,GPM6A
4.170e-02	-3.18	synapse assembly	biological process	GO:0007416	118	2	18204	50	GPM6A,ERBB4
4.193e-02	-3.17	response to stimulus	biological process	GO:0050896	7803	28	18204	50	CLU,ERBB4,TNIK,ZNRF3,CST3,DOCK4,FGFR3,CTNNA2,RORA,DAAM2,PARD3,CADM1,PITPNC1,RYR3,SLC1A2,PTGDS,SOX5,NFIA,GPM6A,GLUL,DTNA,SLC1A3,ATP1A2,ZBTB20,NDRG2,CTNND2,MAML2,PREX2
4.195e-02	-3.17	positive regulation of cellular metabolic process	biological process	GO:0031325	3164	14	18204	50	NFIA,ERBB4,TNIK,CADM1,CLU,MAML2,SLC4A4,NPAS3,RORA,SASH1,ZBTB20,TPD52L1,FGFR3,QKI
4.196e-02	-3.17	breast-carcinoma-ductolobular_carcinoma	COSMIC cancer mutations	breast-carcinoma-ductolobular_carcinoma	1619	9	16828	49	CTNND2,RORA,FGFR3,ABLIM1,PREX2,NDRG2,QKI,CDH20,DTNA
4.196e-02	-3.17	ductolobular_carcinoma	COSMIC cancer mutations	ductolobular_carcinoma	1619	9	16828	49	DTNA,CDH20,QKI,NDRG2,PREX2,FGFR3,ABLIM1,RORA,CTNND2
4.215e-02	-3.17	MFAP5-mediated ovarian cancer cell motility and invasiveness	WikiPathways	WP3301	12	1	5310	19	RYR3
4.216e-02	-3.17	FGFR3c ligand binding and activation	REACTOME pathways	R-HSA-190372	13	1	10285	34	FGFR3
4.216e-02	-3.17	Notch-HLH transcription pathway	REACTOME pathways	R-HSA-350054	13	1	10285	34	MAML2
4.216e-02	-3.17	ERBB2 Activates PTK6 Signaling	REACTOME pathways	R-HSA-8847993	13	1	10285	34	ERBB4
4.216e-02	-3.17	Phospholipase C-mediated cascade; FGFR3	REACTOME pathways	R-HSA-5654227	13	1	10285	34	FGFR3
4.216e-02	-3.17	FGFR3 ligand binding and activation	REACTOME pathways	R-HSA-190239	13	1	10285	34	FGFR3
4.216e-02	-3.17	NOTCH2 intracellular domain regulates transcription	REACTOME pathways	R-HSA-2197563	13	1	10285	34	MAML2
4.226e-02	-3.16	PHF11 (PHD finger protein 11)	protein interactions	51131	127	2	19454	50	NDRG2,GLUL
4.250e-02	-3.16	lung-middle_lobe-carcinoma-adenocarcinoma	COSMIC cancer mutations	lung-middle_lobe-carcinoma-adenocarcinoma	1368	8	16828	49	ATP1A2,HPSE2,TRPM3,ERBB4,RYR3,ATP13A4,SASH1,CTNND2
4.273e-02	-3.15	apical dendrite	cellular component	GO:0097440	17	1	19108	49	CLU
4.282e-02	-3.15	hypothalamus	COSMIC cancer mutations	hypothalamus	15	1	16828	49	QKI
4.282e-02	-3.15	ureter	COSMIC cancer mutations	ureter	15	1	16828	49	FGFR3
4.282e-02	-3.15	SHD (Src homology 2 domain containing transforming protein D)	protein interactions	56961	17	1	19454	50	ERBB4
4.282e-02	-3.15	PAX4 (paired box 4)	protein interactions	5078	17	1	19454	50	NTM
4.282e-02	-3.15	TAGAP (T cell activation RhoGTPase activating protein)	protein interactions	117289	17	1	19454	50	DTNA
4.282e-02	-3.15	FAM163B (family with sequence similarity 163 member B)	protein interactions	642968	17	1	19454	50	CAMK2G
4.282e-02	-3.15	DPP6 (dipeptidyl peptidase like 6)	protein interactions	1804	17	1	19454	50	GPM6A
4.282e-02	-3.15	KRTAP19-3 (keratin associated protein 19-3)	protein interactions	337970	17	1	19454	50	CAMK2G
4.282e-02	-3.15	SEPSECS (Sep (O-phosphoserine) tRNA:Sec (selenocysteine) tRNA synthase)	protein interactions	51091	17	1	19454	50	ABLIM1
4.282e-02	-3.15	NOTCH4 (notch receptor 4)	protein interactions	4855	17	1	19454	50	MAML2
4.282e-02	-3.15	Abr (active BCR-related gene)	protein interactions	109934	17	1	19454	50	DOCK4
4.282e-02	-3.15	Shcbp1 (Shc SH2-domain binding protein 1)	protein interactions	20419	17	1	19454	50	GPC5
4.282e-02	-3.15	Pef1 (penta-EF hand domain containing 1)	protein interactions	67898	17	1	19454	50	QKI
4.282e-02	-3.15	MSANTD2 (Myb/SANT DNA binding domain containing 2)	protein interactions	79684	17	1	19454	50	SOX5
4.286e-02	-3.15	MYB (MYB proto-oncogene, transcription factor)	protein interactions	4602	128	2	19454	50	TRPS1,NFIA
4.286e-02	-3.15	ATF7IP (activating transcription factor 7 interacting protein)	protein interactions	55729	128	2	19454	50	CADM1,SOX5
4.286e-02	-3.15	TEAD2 (TEA domain transcription factor 2)	protein interactions	8463	128	2	19454	50	TRPS1,ZBTB20
4.297e-02	-3.15	RAC1 (Rac family small GTPase 1)	protein interactions	5879	1005	6	19454	50	PREX2,DOCK4,PARD3,AHCYL2,DTNA,SLC1A3
4.302e-02	-3.15	acral	COSMIC cancer mutations	acral	268	3	16828	49	CDH20,PARD3,COL5A3
4.307e-02	-3.14	locomotory exploration behavior	biological process	GO:0035641	16	1	18204	50	ATP1A2
4.307e-02	-3.14	regulation of respiratory system process	biological process	GO:0044065	16	1	18204	50	ATP1A2
4.307e-02	-3.14	regulation of amino acid import across plasma membrane	biological process	GO:0010958	16	1	18204	50	ATP1A2
4.307e-02	-3.14	regulation of Wnt signaling pathway, planar cell polarity pathway	biological process	GO:2000095	16	1	18204	50	ZNRF3
4.307e-02	-3.14	glutamine family amino acid biosynthetic process	biological process	GO:0009084	16	1	18204	50	GLUL
4.307e-02	-3.14	S-adenosylmethionine metabolic process	biological process	GO:0046500	16	1	18204	50	AHCYL2
4.307e-02	-3.14	regulation of amino acid transmembrane transport	biological process	GO:1903789	16	1	18204	50	ATP1A2
4.307e-02	-3.14	nonribosomal peptide biosynthetic process	biological process	GO:0019184	16	1	18204	50	SLC1A2
4.307e-02	-3.14	non-proteinogenic amino acid biosynthetic process	biological process	GO:0170043	16	1	18204	50	SLC1A3
4.311e-02	-3.14	human chr2q34	chromosome location	human chr2q34	23	1	26134	50	ERBB4
4.313e-02	-3.14	Lactose Intolerance	SMPDB pathways	SMP0000458	12	1	1369	5	ATP1A2
4.313e-02	-3.14	Lactose Degradation	SMPDB pathways	SMP0000457	12	1	1369	5	ATP1A2
4.329e-02	-3.14	ovary-carcinoma-mucinous_carcinoma	COSMIC cancer mutations	ovary-carcinoma-mucinous_carcinoma	456	4	16828	49	CAMK2G,TNIK,FGFR3,ERBB4
4.334e-02	-3.14	ovary-carcinoma-clear_cell_carcinoma	COSMIC cancer mutations	ovary-carcinoma-clear_cell_carcinoma	665	5	16828	49	CAMK2G,TNIK,NDRG2,FGFR3,ERBB4
4.346e-02	-3.14	CHD7 (chromodomain helicase DNA binding protein 7)	protein interactions	55636	129	2	19454	50	ZBTB20,SOX5
4.346e-02	-3.14	Lima1 (LIM domain and actin binding 1)	protein interactions	65970	129	2	19454	50	ZBTB20,ABLIM1
4.352e-02	-3.13	skin-chest-malignant_melanoma	COSMIC cancer mutations	skin-chest-malignant_melanoma	114	2	16828	49	PREX2,ERBB4
4.359e-02	-3.13	ZnF_GATA	smart domains	SM00401	12	1	9717	36	TRPS1
4.359e-02	-3.13	DWA	smart domains	SM00523	12	1	9717	36	NFIA
4.368e-02	-3.13	Formin, FH2 domain	gene3d domains	1.20.58.2220	15	1	14470	43	DAAM2
4.379e-02	-3.13	export from cell	biological process	GO:0140352	485	4	18204	50	ATP1A2,PTGDS,CAMK2G,SLC4A4
4.388e-02	-3.13	mucinous_carcinoma	COSMIC cancer mutations	mucinous_carcinoma	458	4	16828	49	ERBB4,FGFR3,TNIK,CAMK2G
4.407e-02	-3.12	DVL1 (dishevelled segment polarity protein 1)	protein interactions	1855	130	2	19454	50	ZNRF3,PARD3
4.410e-02	-3.12	prostate-adenoma	COSMIC cancer mutations	prostate-adenoma	1634	9	16828	49	ERBB4,PARD3,SOX5,TRPM3,COL5A3,ZBTB20,GPC5,NPAS3,SASH1
4.428e-02	-3.12	clear_cell_carcinoma	COSMIC cancer mutations	clear_cell_carcinoma	669	5	16828	49	CAMK2G,TNIK,NDRG2,ERBB4,FGFR3
4.445e-02	-3.11	cell projection organization	biological process	GO:0030030	1200	7	18204	50	CTNNA2,CTNND2,TNIK,PREX2,GPM6A,ABLIM1,PARD3
4.468e-02	-3.11	TRPS1 (transcriptional repressor GATA binding 1)	protein interactions	7227	131	2	19454	50	SOX5,NFIA
4.468e-02	-3.11	ZNF609 (zinc finger protein 609)	protein interactions	23060	131	2	19454	50	NFIA,SOX5
4.468e-02	-3.11	NCOA2 (nuclear receptor coactivator 2)	protein interactions	10499	131	2	19454	50	RORA,NFIA
4.493e-02	-3.10	Cystatin_dom	interpro domains	IPR000010	17	1	18521	50	CST3
4.507e-02	-3.10	ductal_carcinoma	COSMIC cancer mutations	ductal_carcinoma	15798	49	16828	49	PTGDS,GLUL,TNIK,SLC4A4,SLC1A2,CST3,TRPS1,ZNRF3,CTNND2,LSAMP,ABLIM1,NKAIN3,DTNA,PARD3,NPAS3,NHSL1,NDRG2,SLC1A3,FGFR3,MSI2,RYR3,NTM,TPD52L1,CAMK2G,CADM1,ZBTB20,RORA,CDH20,DOCK4,CLU,HPSE2,AHCYL2,QKI,ERBB4,SASH1,DAAM2,SLC25A18,TRPM3,PITPNC1,NFIA,GPC5,COL5A3,ATP1A2,ATP13A4,SOX5,GPM6A,FBXL7,PREX2,MAML2
4.529e-02	-3.09	CYP2E1 (cytochrome P450 family 2 subfamily E member 1)	protein interactions	1571	18	1	19454	50	CLU
4.529e-02	-3.09	OPCML (opioid binding protein/cell adhesion molecule like)	protein interactions	4978	18	1	19454	50	NTM
4.529e-02	-3.09	PTGFR (prostaglandin F receptor)	protein interactions	5737	18	1	19454	50	PTGDS
4.530e-02	-3.09	STRN (striatin)	protein interactions	6801	132	2	19454	50	TNIK,CAMK2G
4.533e-02	-3.09	SHC1 events in ERBB4 signaling	REACTOME pathways	R-HSA-1250347	14	1	10285	34	ERBB4
4.533e-02	-3.09	DCC mediated attractive signaling	REACTOME pathways	R-HSA-418885	14	1	10285	34	ABLIM1
4.558e-02	-3.09	Cell-type Dependent Selectivity of CCK2R Signaling	WikiPathways	WP3679	13	1	5310	19	RYR3
4.558e-02	-3.09	cellular process	biological process	GO:0009987	14996	46	18204	50	ERBB4,CLU,COL5A3,DOCK4,FBXL7,QKI,NTM,PARD3,AHCYL2,NHSL1,GPC5,PITPNC1,GPM6A,SLC25A18,CAMK2G,NDRG2,GLUL,DTNA,ATP1A2,SLC4A4,PREX2,HPSE2,MSI2,ABLIM1,TNIK,CST3,ATP13A4,ZNRF3,CDH20,CTNNA2,LSAMP,TPD52L1,FGFR3,RORA,DAAM2,SLC1A2,SOX5,PTGDS,CADM1,RYR3,NFIA,ZBTB20,CTNND2,SLC1A3,MAML2,TRPM3
4.561e-02	-3.09	normal	COSMIC cancer mutations	normal	16	1	16828	49	FGFR3
4.561e-02	-3.09	renal_pelvis	COSMIC cancer mutations	renal_pelvis	16	1	16828	49	FGFR3
4.561e-02	-3.09	flank	COSMIC cancer mutations	flank	16	1	16828	49	FGFR3
4.561e-02	-3.09	urinary_tract-carcinoma	COSMIC cancer mutations	urinary_tract-carcinoma	16	1	16828	49	FGFR3
4.565e-02	-3.09	ovary-carcinoma-endometrioid_carcinoma	COSMIC cancer mutations	ovary-carcinoma-endometrioid_carcinoma	464	4	16828	49	TNIK,CAMK2G,FGFR3,ERBB4
4.570e-02	-3.09	mammary gland epithelial cell differentiation	biological process	GO:0060644	17	1	18204	50	ERBB4
4.570e-02	-3.09	cell communication by electrical coupling involved in cardiac conduction	biological process	GO:0086064	17	1	18204	50	ATP1A2
4.570e-02	-3.09	regulation of inclusion body assembly	biological process	GO:0090083	17	1	18204	50	CLU
4.570e-02	-3.09	cellular response to ATP	biological process	GO:0071318	17	1	18204	50	RYR3
4.570e-02	-3.09	reverse cholesterol transport	biological process	GO:0043691	17	1	18204	50	CLU
4.570e-02	-3.09	cell migration in hindbrain	biological process	GO:0021535	17	1	18204	50	CTNNA2
4.570e-02	-3.09	T-helper 17 type immune response	biological process	GO:0072538	17	1	18204	50	RORA
4.570e-02	-3.09	cGMP metabolic process	biological process	GO:0046068	17	1	18204	50	RORA
4.570e-02	-3.09	ureter development	biological process	GO:0072189	17	1	18204	50	NFIA
4.570e-02	-3.09	regulation of amyloid fibril formation	biological process	GO:1905906	17	1	18204	50	CLU
4.570e-02	-3.09	microvillus assembly	biological process	GO:0030033	17	1	18204	50	TNIK
4.570e-02	-3.09	T cell mediated cytotoxicity	biological process	GO:0001913	17	1	18204	50	CADM1
4.570e-02	-3.09	membrane depolarization during cardiac muscle cell action potential	biological process	GO:0086012	17	1	18204	50	ATP1A2
4.570e-02	-3.09	protein trimerization	biological process	GO:0070206	17	1	18204	50	SLC1A2
4.570e-02	-3.09	viral genome replication	biological process	GO:0019079	17	1	18204	50	NFIA
4.579e-02	-3.08	endoplasmic reticulum lumen	cellular component	GO:0005788	312	3	19108	49	CST3,CLU,COL5A3
4.582e-02	-3.08	EZR (ezrin)	protein interactions	7430	526	4	19454	50	ABLIM1,AHCYL2,DTNA,TNIK
4.606e-02	-3.08	Stimuli-sensing channels	REACTOME pathways	R-HSA-2672351	104	2	10285	34	TRPM3,RYR3
4.613e-02	-3.08	PDZ	pfam domains	PF00595	122	2	17795	50	PARD3,PREX2
4.631e-02	-3.07	cellular response to growth factor stimulus	biological process	GO:0071363	494	4	18204	50	ERBB4,FGFR3,NFIA,SOX5
4.647e-02	-3.07	SHC1 events in EGFR signaling	REACTOME pathways	R-HSA-180336	245	3	10285	34	CAMK2G,ERBB4,FGFR3
4.647e-02	-3.07	GRB2 events in EGFR signaling	REACTOME pathways	R-HSA-179812	245	3	10285	34	CAMK2G,ERBB4,FGFR3
4.647e-02	-3.07	RAF/MAP kinase cascade	REACTOME pathways	R-HSA-5673001	245	3	10285	34	CAMK2G,ERBB4,FGFR3
4.647e-02	-3.07	SOS-mediated signalling	REACTOME pathways	R-HSA-112412	245	3	10285	34	FGFR3,ERBB4,CAMK2G
4.653e-02	-3.07	NUFIP1 (nuclear FMR1 interacting protein 1)	protein interactions	26747	134	2	19454	50	NTM,GPM6A
4.665e-02	-3.07	Trehalose Degradation	SMPDB pathways	SMP0000467	13	1	1369	5	ATP1A2
4.671e-02	-3.06	phosphatidylcholine transporter activity	molecular function	GO:0008525	18	1	18094	48	PITPNC1
4.671e-02	-3.06	intracellularly gated calcium channel activity	molecular function	GO:0015278	18	1	18094	48	RYR3
4.671e-02	-3.06	heparan sulfate proteoglycan binding	molecular function	GO:0043395	18	1	18094	48	HPSE2
4.671e-02	-3.06	GABA receptor binding	molecular function	GO:0050811	18	1	18094	48	ERBB4
4.673e-02	-3.06	Cystatin	pfam domains	PF00031	17	1	17795	50	CST3
4.673e-02	-3.06	ZZ	pfam domains	PF00569	17	1	17795	50	DTNA
4.677e-02	-3.06	human chr7q31.1	chromosome location	human chr7q31.1	25	1	26134	50	DOCK4
4.716e-02	-3.05	SOX15 (SRY-box transcription factor 15)	protein interactions	6665	135	2	19454	50	NFIA,TRPS1
4.717e-02	-3.05	STAT1 (signal transducer and activator of transcription 1)	protein interactions	6772	315	3	19454	50	FGFR3,DOCK4,CAMK2G
4.722e-02	-3.05	central_nervous_system-brain-glioma-astrocytoma_Grade_IV	COSMIC cancer mutations	central_nervous_system-brain-glioma-astrocytoma_Grade_IV	15813	49	16828	49	RYR3,TPD52L1,NTM,MSI2,RORA,CAMK2G,ZBTB20,CADM1,PARD3,DTNA,NKAIN3,FGFR3,NPAS3,NHSL1,SLC1A3,NDRG2,ZNRF3,TRPS1,CST3,CTNND2,ABLIM1,LSAMP,SLC4A4,SLC1A2,GLUL,PTGDS,TNIK,SOX5,ATP13A4,ATP1A2,FBXL7,GPM6A,PREX2,MAML2,NFIA,PITPNC1,TRPM3,COL5A3,GPC5,QKI,ERBB4,HPSE2,AHCYL2,SLC25A18,DAAM2,SASH1,CLU,CDH20,DOCK4
4.725e-02	-3.05	regulation of ERK1 and ERK2 cascade	biological process	GO:0070372	295	3	18204	50	ERBB4,FGFR3,NDRG2
4.752e-02	-3.05	Leu-rich_rpt_Cys-con_subtyp	interpro domains	IPR006553	18	1	18521	50	FBXL7
4.752e-02	-3.05	Furin_repeat	interpro domains	IPR006212	18	1	18521	50	ERBB4
4.760e-02	-3.05	cell-cell junction assembly	biological process	GO:0007043	127	2	18204	50	CDH20,PARD3
4.760e-02	-3.05	positive regulation of protein serine/threonine kinase activity	biological process	GO:0071902	127	2	18204	50	TPD52L1,SASH1
4.764e-02	-3.04	cation-transporting ATPase complex	cellular component	GO:0090533	19	1	19108	49	ATP1A2
4.764e-02	-3.04	astrocyte projection	cellular component	GO:0097449	19	1	19108	49	SLC1A2
4.764e-02	-3.04	parallel fiber to Purkinje cell synapse	cellular component	GO:0098688	19	1	19108	49	GPM6A
4.764e-02	-3.04	postsynaptic specialization, intracellular component	cellular component	GO:0099091	19	1	19108	49	TNIK
4.774e-02	-3.04	ZNF532 (zinc finger protein 532)	protein interactions	55205	19	1	19454	50	ERBB4
4.774e-02	-3.04	OSM (oncostatin M)	protein interactions	5008	19	1	19454	50	TRPM3
4.774e-02	-3.04	INKA1 (inka box actin regulator 1)	protein interactions	389119	19	1	19454	50	ZBTB20
4.774e-02	-3.04	SPZ1 (spermatogenic leucine zipper 1)	protein interactions	84654	19	1	19454	50	DTNA
4.774e-02	-3.04	LTC4S (leukotriene C4 synthase)	protein interactions	4056	19	1	19454	50	CAMK2G
4.774e-02	-3.04	Mtx1 (metaxin 1)	protein interactions	17827	19	1	19454	50	CAMK2G
4.774e-02	-3.04	HBEGF (heparin binding EGF like growth factor)	protein interactions	1839	19	1	19454	50	ERBB4
4.774e-02	-3.04	PHYHIPL (phytanoyl-CoA 2-hydroxylase interacting protein like)	protein interactions	84457	19	1	19454	50	GPM6A
4.774e-02	-3.04	FBXO27 (F-box protein 27)	protein interactions	126433	19	1	19454	50	CLU
4.774e-02	-3.04	RRAD (RRAD, Ras related glycolysis inhibitor and calcium channel regulator)	protein interactions	6236	19	1	19454	50	CAMK2G
4.774e-02	-3.04	RIT2 (Ras like without CAAX 2)	protein interactions	6014	19	1	19454	50	DTNA
4.774e-02	-3.04	C3orf62 (chromosome 3 open reading frame 62)	protein interactions	375341	19	1	19454	50	ATP1A2
4.782e-02	-3.04	regulation of multicellular organismal development	biological process	GO:2000026	1484	8	18204	50	GLUL,ERBB4,QKI,SOX5,SASH1,TRPS1,DAAM2,PARD3
4.785e-02	-3.04	anion binding	molecular function	GO:0043168	2412	11	18094	48	PITPNC1,PARD3,ATP13A4,PTGDS,GLUL,ATP1A2,FGFR3,ERBB4,TNIK,SLC1A3,CAMK2G
4.804e-02	-3.04	muscle system process	biological process	GO:0003012	297	3	18204	50	RYR3,ATP1A2,DTNA
4.804e-02	-3.04	carboxylic acid transport	biological process	GO:0046942	297	3	18204	50	SLC1A2,SLC25A18,SLC1A3
4.804e-02	-3.04	positive regulation of cytokine production	biological process	GO:0001819	500	4	18204	50	CLU,CADM1,RORA,ZBTB20
4.804e-02	-3.04	skeletal system development	biological process	GO:0001501	500	4	18204	50	TRPS1,FGFR3,NFIA,SOX5
4.815e-02	-3.03	FH2	prosite domains	PS51444	15	1	12186	40	DAAM2
4.815e-02	-3.03	CNH	prosite domains	PS50219	15	1	12186	40	TNIK
4.827e-02	-3.03	glial cell development	biological process	GO:0021782	128	2	18204	50	PARD3,CLU
4.832e-02	-3.03	positive regulation of circadian rhythm	biological process	GO:0042753	18	1	18204	50	RORA
4.832e-02	-3.03	receptor catabolic process	biological process	GO:0032801	18	1	18204	50	ZNRF3
4.832e-02	-3.03	negative regulation of sodium ion transport	biological process	GO:0010766	18	1	18204	50	ATP1A2
4.832e-02	-3.03	myelin maintenance	biological process	GO:0043217	18	1	18204	50	CLU
4.832e-02	-3.03	regulation of extracellular matrix disassembly	biological process	GO:0010715	18	1	18204	50	CST3
4.832e-02	-3.03	response to misfolded protein	biological process	GO:0051788	18	1	18204	50	CLU
4.832e-02	-3.03	positive regulation of myelination	biological process	GO:0031643	18	1	18204	50	PARD3
4.832e-02	-3.03	dendritic spine morphogenesis	biological process	GO:0060997	18	1	18204	50	CTNND2
4.832e-02	-3.03	dicarboxylic acid catabolic process	biological process	GO:0043649	18	1	18204	50	GLUL
4.836e-02	-3.03	Signalling to p38 via RIT and RIN	REACTOME pathways	R-HSA-187706	249	3	10285	34	CAMK2G,FGFR3,ERBB4
4.836e-02	-3.03	ARMS-mediated activation	REACTOME pathways	R-HSA-170984	249	3	10285	34	CAMK2G,ERBB4,FGFR3
4.839e-02	-3.03	central_nervous_system-optic_nerve-glioma-astrocytoma_Grade_I	COSMIC cancer mutations	central_nervous_system-optic_nerve-glioma-astrocytoma_Grade_I	17	1	16828	49	QKI
4.839e-02	-3.03	skin-non_chronically_sun_exposed_site-malignant_melanoma	COSMIC cancer mutations	skin-non_chronically_sun_exposed_site-malignant_melanoma	17	1	16828	49	FGFR3
4.839e-02	-3.03	breast-carcinoma-neuroendocrine_carcinoma	COSMIC cancer mutations	breast-carcinoma-neuroendocrine_carcinoma	17	1	16828	49	FGFR3
4.839e-02	-3.03	non_chronically_sun_exposed_site	COSMIC cancer mutations	non_chronically_sun_exposed_site	17	1	16828	49	FGFR3
4.839e-02	-3.03	squamous_cell_carcinoma_BRAF_inhibitor_related	COSMIC cancer mutations	squamous_cell_carcinoma_BRAF_inhibitor_related	17	1	16828	49	FGFR3
4.839e-02	-3.03	skin-other-verrucal_keratosis_BRAF_inhibitor_related	COSMIC cancer mutations	skin-other-verrucal_keratosis_BRAF_inhibitor_related	17	1	16828	49	FGFR3
4.839e-02	-3.03	optic_nerve	COSMIC cancer mutations	optic_nerve	17	1	16828	49	QKI
4.839e-02	-3.03	skin-carcinoma-squamous_cell_carcinoma_BRAF_inhibitor_related	COSMIC cancer mutations	skin-carcinoma-squamous_cell_carcinoma_BRAF_inhibitor_related	17	1	16828	49	FGFR3
4.839e-02	-3.03	verrucal_keratosis_BRAF_inhibitor_related	COSMIC cancer mutations	verrucal_keratosis_BRAF_inhibitor_related	17	1	16828	49	FGFR3
4.842e-02	-3.03	TBL1X (transducin beta like 1 X-linked)	protein interactions	6907	137	2	19454	50	SOX5,NFIA
4.843e-02	-3.03	organic acid transport	biological process	GO:0015849	298	3	18204	50	SLC1A2,SLC25A18,SLC1A3
4.849e-02	-3.03	Synthesis of Prostaglandins (PG) and Thromboxanes (TX)	REACTOME pathways	R-HSA-2162123	15	1	10285	34	PTGDS
4.849e-02	-3.03	ERBB2 Regulates Cell Motility	REACTOME pathways	R-HSA-6785631	15	1	10285	34	ERBB4
4.856e-02	-3.02	protein-folding chaperone binding	molecular function	GO:0051087	133	2	18094	48	ATP1A2,CLU
4.859e-02	-3.02	human chr18q12.1	chromosome location	human chr18q12.1	26	1	26134	50	DTNA
4.884e-02	-3.02	Frs2-mediated activation	REACTOME pathways	R-HSA-170968	250	3	10285	34	CAMK2G,FGFR3,ERBB4
4.905e-02	-3.01	OR2A4 (olfactory receptor family 2 subfamily A member 4)	protein interactions	79541	138	2	19454	50	GLUL,NDRG2
4.924e-02	-3.01	alkali metal ion binding	molecular function	GO:0031420	19	1	18094	48	ATP1A2
4.932e-02	-3.01	MAPK1/MAPK3 signaling	REACTOME pathways	R-HSA-5684996	251	3	10285	34	FGFR3,ERBB4,CAMK2G
4.933e-02	-3.01	parathyroid	COSMIC cancer mutations	parathyroid	476	4	16828	49	GPC5,GPM6A,TRPS1,RYR3
4.936e-02	-3.01	-	gene3d domains	2.60.120.1000	17	1	14470	43	COL5A3
4.962e-02	-3.00	thalamus	COSMIC cancer mutations	thalamus	284	3	16828	49	QKI,FGFR3,DTNA
4.968e-02	-3.00	KRTAP9-3 (keratin associated protein 9-3)	protein interactions	83900	139	2	19454	50	SLC25A18,NTM
4.968e-02	-3.00	DUSP22 (dual specificity phosphatase 22)	protein interactions	56940	139	2	19454	50	QKI,CTNNA2
4.980e-02	-3.00	Prolonged ERK activation events	REACTOME pathways	R-HSA-169893	252	3	10285	34	CAMK2G,FGFR3,ERBB4