Gene Ontology Enrichment Results

Homer de novo Motif Enrichment Results
Known Motif Enrichment Results

Text file version of complete results (i.e. open with Excel)

biological process: Functional groupings of proteins (Gene Ontology)

molecular function: Mechanistic actions of proteins (Gene Ontology)

cellular component: Protein localization (Gene Ontology)

chromosome location: Genes with similar chromosome localization (NCBI Gene)

KEGG pathways: Groups of proteins in the same pathways (KEGG)

protein interactions: "Proteins interacting with a common protein (BIND, EcoCyc, HPRD)" (NCBI Gene)

interpro domains: Proteins with similar domains and features (Interpro)

pfam domains: Proteins with similar domains and features (Pfam)

smart domains: Proteins with similar domains and features (SMART)

gene3d domains: Proteins with similar domains and features (Gene3D)

prosite domains: Proteins with similar domains and features (Prosite)

prints domains: Proteins with similar domains and features (PRINTS)

MSigDB lists: "Genes sets for pathways, factor/miRNA target predictions, expression patterns, etc." (MSigDB)

BIOCYC pathways: Groups of proteins in the same pathways (BIOCYC)

COSMIC cancer mutations: Genes mutated in similar cancers (COSMIC)

GWAS genes: Genes mutated in similar diseases (GWAS Catalog)

Lipid Maps pathways: Groups of proteins in the same lipid pathways (Lipid Maps/Biosystems)

Pathway Interaction DB: Groups of proteins in the same pathways (Pathway Interaction Database)

REACTOME pathways: Groups of proteins in the same pathways (REACTOME)

SMPDB pathways: Groups of proteins in the same pathways (SMPDB)

WikiPathways: Groups of proteins in the same pathways (Wikipathways)

Enriched Categories

P-value	ln(P)	Term	GO Tree	GO ID	# of Genes in Term	# of Target Genes in Term	# of Total Genes	# of Target Genes	Common Genes
2.587e-12	-26.68	myelodysplastic_syndrome	COSMIC cancer mutations	myelodysplastic_syndrome	1174	21	16828	49	HPSE2,SOX5,KALRN,NAV2,CAMK2G,DCLK2,NTRK2,PARD3,ATP1A2,SLC1A2,ADCY2,LRP1B,NTRK3,RYR3,PRKCA,RPS6KA2,LSAMP,NKAIN3,NPAS3,ERBB4,NRG3
2.587e-12	-26.68	haematopoietic_and_lymphoid_tissue-haematopoietic_neoplasm-myelodysplastic_syndrome	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue-haematopoietic_neoplasm-myelodysplastic_syndrome	1174	21	16828	49	NKAIN3,LSAMP,ERBB4,NRG3,NPAS3,ADCY2,LRP1B,RPS6KA2,RYR3,NTRK3,PRKCA,PARD3,ATP1A2,SLC1A2,HPSE2,NAV2,DCLK2,NTRK2,CAMK2G,SOX5,KALRN
5.207e-11	-23.68	nervous system development	biological process	GO:0007399	2185	25	18204	50	LSAMP,CTNNA2,CTNND2,SOX5,GPM6A,PARD3,NTRK3,RFX4,RORA,NRXN1,ATP1A2,DCLK2,NRG3,MSI2,NTRK2,SLC1A2,NAV2,DGKG,GFAP,ERBB4,CAMK2G,NTM,NDRG2,KALRN,TNC
1.654e-10	-22.52	upper_aerodigestive_tract-mouth-carcinoma-squamous_cell_carcinoma	COSMIC cancer mutations	upper_aerodigestive_tract-mouth-carcinoma-squamous_cell_carcinoma	6953	42	16828	49	NTRK3,RYR3,PRKCA,NTM,DGKG,FMN2,RPS6KA2,NEBL,RFX4,DTNA,GFAP,TRPM3,SFXN5,NRG3,RORA,KALRN,GPM6A,NAV2,DCLK2,MACF1,PITPNC1,MGAT4C,ABLIM1,SYNE1,SORBS1,SLC1A2,PARD3,NDRG2,ADCY2,LRP1B,CDH20,GPC5,SLC4A4,NRXN1,ERBB4,LSAMP,SOX5,CAMK2G,CTNND2,PSD2,TNC,ATP1A2
2.292e-10	-22.20	haematopoietic_and_lymphoid_tissue-haematopoietic_neoplasm	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue-haematopoietic_neoplasm	764	16	16828	49	ERBB4,NRG3,NKAIN3,LSAMP,RYR3,ADCY2,GPC5,LRP1B,SLC1A2,PARD3,ATP1A2,NAV2,NTRK2,SOX5,KALRN,HPSE2
6.541e-10	-21.15	haematopoietic_and_lymphoid_tissue-lymph_node-lymphoid_neoplasm-mantle_cell_lymphoma	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue-lymph_node-lymphoid_neoplasm-mantle_cell_lymphoma	476	13	16828	49	GPM6A,NAV2,SYNE1,CTNND2,PRKCA,RYR3,GPC5,LRP1B,TRPM3,SFXN5,ERBB4,NRG3,LSAMP
2.718e-09	-19.72	lymph_node	COSMIC cancer mutations	lymph_node	1703	21	16828	49	SYNE1,CTNND2,PARD3,SOX5,CAMK2G,NTRK2,GPM6A,NAV2,TRPM3,SFXN5,ERBB4,NRG3,LSAMP,PRKCA,NTRK3,RYR3,RPS6KA2,LRP1B,DTNA,GPC5,NEBL
6.313e-09	-18.88	mouth	COSMIC cancer mutations	mouth	9004	45	16828	49	HPSE2,ABLIM1,RORA,MACF1,GPM6A,NAV2,SLC1A2,SORBS1,RFX4,NEBL,NTRK3,TRPM3,GFAP,SOX5,NTRK2,TNC,CTNND2,CDH20,LSAMP,NPAS3,PITPNC1,MGAT4C,KALRN,DCLK2,PARD3,SYNE1,DTNA,PRKCA,NTM,RYR3,RPS6KA2,FMN2,DGKG,SFXN5,NRG3,CAMK2G,ATP1A2,PSD2,NDRG2,LRP1B,GPC5,ADCY2,NRXN1,SLC4A4,ERBB4
8.164e-09	-18.62	mantle_cell_lymphoma	COSMIC cancer mutations	mantle_cell_lymphoma	2849	26	16828	49	ERBB4,LSAMP,LRP1B,GPC5,ADCY2,PSD2,CTNND2,TNC,NTRK2,SOX5,NRG3,TRPM3,SFXN5,NKAIN3,FMN2,PRKCA,RYR3,RFX4,NEBL,SLC1A2,SYNE1,PARD3,NAV2,GPM6A,KALRN,HPSE2
1.026e-08	-18.39	system development	biological process	GO:0048731	3533	28	18204	50	KALRN,TNC,NDRG2,NTM,DGKG,GFAP,ERBB4,CAMK2G,SYNE1,NAV2,MSI2,SLC1A2,NTRK2,ATP1A2,DCLK2,NRG3,RORA,NRXN1,RFX4,PRKCA,GPM6A,PARD3,NTRK3,NEBL,SOX5,CTNNA2,CTNND2,LSAMP
1.793e-08	-17.84	acute_myeloid_leukaemia_therapy_related	COSMIC cancer mutations	acute_myeloid_leukaemia_therapy_related	1523	19	16828	49	CTNND2,PARD3,NTRK2,NAV2,KALRN,RORA,SOX5,HPSE2,NRG3,ERBB4,NKAIN3,LSAMP,FMN2,DGKG,RYR3,LRP1B,GPC5,ADCY2,NEBL
1.793e-08	-17.84	haematopoietic_and_lymphoid_tissue-haematopoietic_neoplasm-acute_myeloid_leukaemia_therapy_related	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue-haematopoietic_neoplasm-acute_myeloid_leukaemia_therapy_related	1523	19	16828	49	GPC5,LRP1B,ADCY2,NEBL,DGKG,FMN2,RYR3,NKAIN3,LSAMP,ERBB4,NRG3,HPSE2,NTRK2,NAV2,KALRN,RORA,SOX5,PARD3,CTNND2
1.947e-08	-17.75	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-mantle_cell_lymphoma	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-mantle_cell_lymphoma	2737	25	16828	49	ERBB4,LSAMP,ADCY2,LRP1B,GPC5,CTNND2,PSD2,TNC,SOX5,NTRK2,SFXN5,NRG3,NKAIN3,RYR3,PRKCA,FMN2,NEBL,RFX4,SYNE1,SLC1A2,PARD3,KALRN,NAV2,GPM6A,HPSE2
2.762e-08	-17.40	multicellular organism development	biological process	GO:0007275	3957	29	18204	50	NDRG2,TNC,KALRN,SYNE1,NAV2,SLC1A2,NTRK2,MSI2,NTM,CAMK2G,ERBB4,GFAP,DGKG,RFX4,PRKCA,NRG3,DCLK2,ATP1A2,NRXN1,RORA,CTNND2,CTNNA2,LSAMP,CDH20,NEBL,NTRK3,GPM6A,PARD3,SOX5
2.915e-08	-17.35	chondroblastoma	COSMIC cancer mutations	chondroblastoma	534	12	16828	49	ADCY2,GPC5,LRP1B,RYR3,FMN2,LSAMP,NKAIN3,SFXN5,NRG3,SOX5,GPM6A,CTNND2
4.276e-08	-16.97	acute_lymphoblastic_B_cell_leukaemia	COSMIC cancer mutations	acute_lymphoblastic_B_cell_leukaemia	3828	29	16828	49	MGAT4C,HPSE2,GPM6A,NAV2,KALRN,RORA,PARD3,SLC1A2,SYNE1,NEBL,FMN2,RYR3,NTRK3,NTM,NKAIN3,NRG3,GLIS3,NTRK2,SOX5,TNC,CTNND2,PSD2,ADCY2,GPC5,LRP1B,LSAMP,ERBB4,SLC4A4,NRXN1
4.276e-08	-16.97	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-acute_lymphoblastic_B_cell_leukaemia	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-acute_lymphoblastic_B_cell_leukaemia	3828	29	16828	49	NEBL,NTM,NTRK3,RYR3,FMN2,NKAIN3,GLIS3,NRG3,HPSE2,MGAT4C,KALRN,RORA,GPM6A,NAV2,PARD3,SYNE1,SLC1A2,GPC5,LRP1B,ADCY2,LSAMP,NRXN1,SLC4A4,ERBB4,SOX5,NTRK2,TNC,PSD2,CTNND2
5.023e-08	-16.81	prostate-carcinoma	COSMIC cancer mutations	prostate-carcinoma	9000	44	16828	49	PSD2,ADCY2,LRP1B,GPC5,ERBB4,SLC4A4,NRXN1,PITPNC1,DCLK2,KALRN,MSI2,SLC14A1,PARD3,SYNE1,DTNA,DGKG,FMN2,RPS6KA2,RYR3,PRKCA,NTM,NKAIN3,NRG3,GLIS3,SFXN5,NTRK2,SOX5,TNC,CTNND2,CDH20,LSAMP,NPAS3,ABLIM1,HPSE2,GPM6A,NAV2,MACF1,RORA,SORBS1,SLC1A2,NEBL,RFX4,NTRK3,TRPM3
5.055e-08	-16.80	brainstem	COSMIC cancer mutations	brainstem	3102	26	16828	49	SYNE1,SLC1A2,SLC14A1,PARD3,KALRN,RORA,GPM6A,NAV2,HPSE2,SFXN5,NRG3,NKAIN3,RYR3,PRKCA,FMN2,CTNND2,PSD2,TNC,SOX5,NPAS3,ERBB4,LSAMP,ADCY2,GPC5,LRP1B,CDH20
1.045e-07	-16.07	nodular	COSMIC cancer mutations	nodular	1515	18	16828	49	NTRK3,DGKG,FMN2,NEBL,CDH20,LRP1B,SLC4A4,GLIS3,NPAS3,ERBB4,KALRN,NTRK2,DCLK2,MACF1,ABLIM1,CTNND2,SYNE1,ATP1A2
1.173e-07	-15.96	central_nervous_system-brainstem-glioma-astrocytoma_Grade_IV	COSMIC cancer mutations	central_nervous_system-brainstem-glioma-astrocytoma_Grade_IV	2531	23	16828	49	SYNE1,SLC14A1,PARD3,NAV2,GPM6A,RORA,KALRN,HPSE2,NRG3,SFXN5,NKAIN3,FMN2,PRKCA,RYR3,PSD2,CTNND2,SOX5,ERBB4,LSAMP,GPC5,LRP1B,CDH20,ADCY2
1.314e-07	-15.84	Burkitt_lymphoma	COSMIC cancer mutations	Burkitt_lymphoma	2119	21	16828	49	LRP1B,RFX4,GPC5,ADCY2,RYR3,FMN2,DGKG,LSAMP,NKAIN3,NPAS3,NRG3,ERBB4,HPSE2,KALRN,SOX5,NTRK2,NAV2,GPM6A,PARD3,CTNND2,SLC1A2
1.314e-07	-15.84	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-Burkitt_lymphoma	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-Burkitt_lymphoma	2119	21	16828	49	RYR3,DGKG,FMN2,RFX4,LRP1B,GPC5,ADCY2,NPAS3,ERBB4,NRG3,LSAMP,NKAIN3,KALRN,SOX5,NTRK2,NAV2,GPM6A,HPSE2,CTNND2,SLC1A2,PARD3
1.551e-07	-15.68	central_nervous_system-brain-primitive_neuroectodermal_tumour-medulloblastoma	COSMIC cancer mutations	central_nervous_system-brain-primitive_neuroectodermal_tumour-medulloblastoma	7205	39	16828	49	ADCY2,LRP1B,GPC5,ERBB4,NPAS3,SLC4A4,NRXN1,LSAMP,NTRK2,SOX5,CTNND2,PSD2,DGKG,FMN2,RPS6KA2,NTRK3,RYR3,NTM,PRKCA,NEBL,RFX4,NRG3,GLIS3,TRPM3,SFXN5,NKAIN3,GPM6A,NAV2,MACF1,DCLK2,KALRN,RORA,ABLIM1,HPSE2,PITPNC1,SORBS1,SLC1A2,SYNE1,PARD3
1.886e-07	-15.48	trunk	COSMIC cancer mutations	trunk	3554	27	16828	49	LSAMP,NRXN1,NPAS3,ERBB4,CDH20,LRP1B,ATP1A2,TNC,CTNND2,SOX5,NTRK2,GLIS3,NRG3,NEBL,RYR3,NTRK3,RPS6KA2,DGKG,PARD3,SLC14A1,SYNE1,HPSE2,ABLIM1,MGAT4C,KALRN,MACF1,DCLK2
1.955e-07	-15.45	cerebellum	COSMIC cancer mutations	cerebellum	769	13	16828	49	NRG3,ERBB4,NPAS3,NRXN1,RYR3,NEBL,LRP1B,GPC5,CTNND2,PARD3,NTRK2,ABLIM1,HPSE2
2.603e-07	-15.16	central_nervous_system-cerebellum-primitive_neuroectodermal_tumour-medulloblastoma-SHH_subtype	COSMIC cancer mutations	central_nervous_system-cerebellum-primitive_neuroectodermal_tumour-medulloblastoma-SHH_subtype	653	12	16828	49	PARD3,NRXN1,NPAS3,CTNND2,NRG3,ERBB4,HPSE2,ABLIM1,LRP1B,NEBL,RYR3,NTRK2
2.608e-07	-15.16	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-diffuse_large_B_cell_lymphoma	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-diffuse_large_B_cell_lymphoma	3608	27	16828	49	PSD2,CTNND2,ATP1A2,TNC,SOX5,ERBB4,LSAMP,LRP1B,CDH20,GPC5,ADCY2,SLC1A2,SYNE1,PARD3,MACF1,GPM6A,NAV2,RORA,KALRN,HPSE2,NRG3,NKAIN3,FMN2,DGKG,PRKCA,RYR3,NEBL
2.646e-07	-15.15	SHH_subtype	COSMIC cancer mutations	SHH_subtype	654	12	16828	49	CTNND2,PARD3,NTRK2,ABLIM1,HPSE2,ERBB4,NRG3,NRXN1,NPAS3,RYR3,LRP1B,NEBL
2.803e-07	-15.09	diffuse_large_B_cell_lymphoma	COSMIC cancer mutations	diffuse_large_B_cell_lymphoma	4151	29	16828	49	NEBL,DTNA,RYR3,PRKCA,FMN2,DGKG,NKAIN3,NRG3,HPSE2,KALRN,RORA,NAV2,GPM6A,MACF1,PARD3,SYNE1,SLC1A2,ADCY2,LRP1B,CDH20,GPC5,LSAMP,ERBB4,SOX5,NTRK2,TNC,ATP1A2,CTNND2,PSD2
2.811e-07	-15.08	generation of neurons	biological process	GO:0048699	1158	15	18204	50	GPM6A,PARD3,NTM,DGKG,SOX5,GFAP,ERBB4,CTNNA2,CTNND2,NTRK2,DCLK2,RORA,NRXN1,KALRN,TNC
2.862e-07	-15.07	neurogenesis	biological process	GO:0022008	1334	16	18204	50	NTRK2,NAV2,CTNNA2,CTNND2,GFAP,SOX5,DGKG,ERBB4,GPM6A,PARD3,NTM,NRXN1,KALRN,RORA,TNC,DCLK2
2.879e-07	-15.06	plasma_cell_myeloma	COSMIC cancer mutations	plasma_cell_myeloma	1263	16	16828	49	NRG3,NTM,RYR3,RPS6KA2,FMN2,LRP1B,ADCY2,NEBL,SYNE1,CTNND2,TNC,MACF1,NTRK2,GPM6A,HPSE2,ABLIM1
2.879e-07	-15.06	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-plasma_cell_myeloma	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-plasma_cell_myeloma	1263	16	16828	49	LRP1B,ADCY2,NEBL,NTM,RYR3,RPS6KA2,FMN2,NRG3,HPSE2,ABLIM1,NTRK2,MACF1,GPM6A,TNC,SYNE1,CTNND2
3.602e-07	-14.84	central_nervous_system-brain-primitive_neuroectodermal_tumour-medulloblastoma-large_cell	COSMIC cancer mutations	central_nervous_system-brain-primitive_neuroectodermal_tumour-medulloblastoma-large_cell	1117	15	16828	49	SOX5,KALRN,NAV2,PARD3,SYNE1,SLC1A2,ADCY2,GPC5,CDH20,LRP1B,RYR3,DGKG,FMN2,NRG3,ERBB4
3.877e-07	-14.76	skin-trunk-malignant_melanoma-nodular	COSMIC cancer mutations	skin-trunk-malignant_melanoma-nodular	1291	16	16828	49	ATP1A2,SYNE1,CTNND2,ABLIM1,KALRN,MACF1,DCLK2,NTRK2,GLIS3,NPAS3,ERBB4,CDH20,LRP1B,NEBL,NTRK3,DGKG
3.882e-07	-14.76	lung-right_lower_lobe-carcinoma-adenocarcinoma	COSMIC cancer mutations	lung-right_lower_lobe-carcinoma-adenocarcinoma	5692	34	16828	49	SOX5,NTRK2,ATP1A2,TNC,PSD2,CTNND2,GPC5,LRP1B,CDH20,ADCY2,LSAMP,SLC4A4,NPAS3,ERBB4,HPSE2,MGAT4C,KALRN,MACF1,GPM6A,NAV2,SLC14A1,PARD3,SYNE1,SORBS1,DTNA,NEBL,NTM,NTRK3,RYR3,FMN2,DGKG,NKAIN3,TRPM3,NRG3
3.882e-07	-14.76	right_lower_lobe	COSMIC cancer mutations	right_lower_lobe	5692	34	16828	49	ERBB4,SLC4A4,NPAS3,LSAMP,ADCY2,GPC5,LRP1B,CDH20,CTNND2,PSD2,TNC,ATP1A2,NTRK2,SOX5,NRG3,TRPM3,NKAIN3,DGKG,FMN2,RYR3,NTRK3,NTM,NEBL,DTNA,SORBS1,SYNE1,PARD3,SLC14A1,GPM6A,NAV2,MACF1,KALRN,MGAT4C,HPSE2
5.510e-07	-14.41	cell periphery	cellular component	GO:0071944	6020	33	19108	50	LSAMP,SLC4A4,NAV2,SLC1A2,ERBB4,GPM6A,TNC,NTM,CDH20,PARD3,CTNND2,CTNNA2,GPC5,DTNA,HPSE2,SYNE1,FMN2,RYR3,PRKCA,SLC14A1,MACF1,NTRK3,LRP1B,NRXN1,NKAIN3,DGKG,TRPM3,NRG3,SORBS1,ATP1A2,NTRK2,ADCY2,PSD2
6.636e-07	-14.23	chronic_lymphocytic_leukaemia-small_lymphocytic_lymphoma	COSMIC cancer mutations	chronic_lymphocytic_leukaemia-small_lymphocytic_lymphoma	3511	26	16828	49	NPAS3,SLC4A4,ERBB4,LSAMP,LRP1B,GPC5,ADCY2,PSD2,CTNND2,NTRK2,TRPM3,NRG3,PRKCA,NTRK3,RYR3,FMN2,DTNA,SYNE1,PARD3,MSI2,KALRN,MACF1,NAV2,PITPNC1,HPSE2,MGAT4C
6.636e-07	-14.23	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-chronic_lymphocytic_leukaemia-small_lymphocytic_lymphoma	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-chronic_lymphocytic_leukaemia-small_lymphocytic_lymphoma	3511	26	16828	49	ADCY2,GPC5,LRP1B,ERBB4,SLC4A4,NPAS3,LSAMP,NTRK2,CTNND2,PSD2,FMN2,NTRK3,RYR3,PRKCA,DTNA,NRG3,TRPM3,NAV2,MACF1,KALRN,MGAT4C,HPSE2,PITPNC1,SYNE1,MSI2,PARD3
7.801e-07	-14.06	neuron differentiation	biological process	GO:0030182	1081	14	18204	50	CTNNA2,CTNND2,NTRK2,GPM6A,PARD3,NTM,GFAP,DGKG,ERBB4,DCLK2,KALRN,NRXN1,RORA,TNC
8.252e-07	-14.01	intestinal_adenocarcinoma	COSMIC cancer mutations	intestinal_adenocarcinoma	7225	38	16828	49	LRP1B,CDH20,ADCY2,LSAMP,NRXN1,SLC4A4,NPAS3,ERBB4,SOX5,NTRK2,ATP1A2,TNC,PSD2,CTNND2,RFX4,NEBL,NTM,PRKCA,NTRK3,RYR3,RPS6KA2,DGKG,FMN2,SFXN5,TRPM3,GFAP,NRG3,PITPNC1,HPSE2,RORA,KALRN,MACF1,DCLK2,NAV2,SLC14A1,PARD3,SYNE1,SLC1A2
8.252e-07	-14.01	stomach-carcinoma-intestinal_adenocarcinoma	COSMIC cancer mutations	stomach-carcinoma-intestinal_adenocarcinoma	7225	38	16828	49	CTNND2,PSD2,TNC,ATP1A2,SOX5,NTRK2,SLC4A4,NPAS3,NRXN1,ERBB4,LSAMP,ADCY2,CDH20,LRP1B,SYNE1,SLC1A2,PARD3,SLC14A1,KALRN,RORA,NAV2,DCLK2,MACF1,HPSE2,PITPNC1,GFAP,TRPM3,SFXN5,NRG3,RYR3,NTRK3,NTM,PRKCA,FMN2,DGKG,RPS6KA2,NEBL,RFX4
8.927e-07	-13.93	anatomical structure development	biological process	GO:0048856	5207	31	18204	50	CTNND2,CTNNA2,LSAMP,CDH20,NEBL,PARD3,GPM6A,NTRK3,SOX5,RFX4,ABLIM1,PRKCA,NRG3,ATP1A2,FMN2,DCLK2,RORA,NRXN1,SYNE1,NAV2,MSI2,SLC1A2,NTRK2,NTM,ERBB4,CAMK2G,DGKG,GFAP,NDRG2,TNC,KALRN
9.499e-07	-13.87	cell projection	cellular component	GO:0042995	2398	20	19108	50	SYNE1,CTNNA2,NDRG2,ATP1A2,DTNA,CTNND2,NTRK3,CAMK2G,PSD2,MACF1,PRKCA,ADCY2,NTRK2,FMN2,GPM6A,SLC1A2,ABLIM1,NRXN1,GFAP,PARD3
9.933e-07	-13.82	cell junction assembly	biological process	GO:0034329	285	8	18204	50	NRXN1,ERBB4,PARD3,GPM6A,NRG3,CDH20,SORBS1,PRKCA
1.170e-06	-13.66	soft_tissue-blood_vessel-angiosarcoma	COSMIC cancer mutations	soft_tissue-blood_vessel-angiosarcoma	2192	20	16828	49	NKAIN3,LSAMP,NRG3,ERBB4,NEBL,ADCY2,GPC5,CDH20,LRP1B,FMN2,RYR3,PARD3,SLC1A2,CTNND2,SYNE1,HPSE2,GPM6A,NAV2,NTRK2,SOX5
1.170e-06	-13.66	angiosarcoma	COSMIC cancer mutations	angiosarcoma	2192	20	16828	49	FMN2,RYR3,CDH20,LRP1B,GPC5,NEBL,ADCY2,ERBB4,NRG3,NKAIN3,LSAMP,NTRK2,GPM6A,NAV2,SOX5,HPSE2,SLC1A2,SYNE1,CTNND2,PARD3
1.224e-06	-13.61	plasma membrane	cellular component	GO:0005886	5538	31	19108	50	CDH20,PARD3,NTM,LSAMP,ERBB4,GPM6A,SLC1A2,SLC4A4,PRKCA,RYR3,SLC14A1,FMN2,NTRK3,MACF1,CTNND2,SYNE1,CTNNA2,GPC5,HPSE2,DTNA,NRG3,LRP1B,NRXN1,DGKG,TRPM3,NKAIN3,ADCY2,NTRK2,PSD2,SORBS1,ATP1A2
1.235e-06	-13.60	NTRK2 (neurotrophic receptor tyrosine kinase 2)	protein interactions	4915	135	6	19454	50	PARD3,NTRK3,NTRK2,ERBB4,DTNA,ABLIM1
1.343e-06	-13.52	blood_vessel	COSMIC cancer mutations	blood_vessel	2211	20	16828	49	CTNND2,SYNE1,SLC1A2,PARD3,SOX5,NAV2,GPM6A,NTRK2,HPSE2,NRG3,ERBB4,LSAMP,NKAIN3,RYR3,FMN2,ADCY2,NEBL,LRP1B,GPC5,CDH20
1.499e-06	-13.41	cell junction organization	biological process	GO:0034330	532	10	18204	50	CDH20,SORBS1,PRKCA,CTNND2,NRXN1,ERBB4,TNC,PARD3,GPM6A,NRG3
1.623e-06	-13.33	CTNNA1 (catenin alpha 1)	protein interactions	1495	325	8	19454	50	PARD3,CTNNA2,MACF1,SORBS1,NTRK3,ABLIM1,NEBL,DTNA
1.693e-06	-13.29	NS-malignant_melanoma	COSMIC cancer mutations	NS-malignant_melanoma	3420	25	16828	49	PSD2,CTNND2,ATP1A2,TNC,GPC5,LRP1B,ADCY2,ERBB4,NRXN1,MACF1,NAV2,KALRN,MGAT4C,PITPNC1,SYNE1,PARD3,RPS6KA2,FMN2,DGKG,PRKCA,RFX4,NEBL,NRG3,TRPM3,GLIS3
1.742e-06	-13.26	pharynx	COSMIC cancer mutations	pharynx	2696	22	16828	49	GPC5,LRP1B,RFX4,DTNA,FMN2,DGKG,RPS6KA2,RYR3,PRKCA,NRG3,SLC4A4,NPAS3,SFXN5,PITPNC1,MACF1,NTRK2,SLC14A1,ATP1A2,SORBS1,SLC1A2,CTNND2,SYNE1
1.826e-06	-13.21	right_upper_lobe	COSMIC cancer mutations	right_upper_lobe	10376	45	16828	49	DTNA,RFX4,NEBL,FMN2,DGKG,PRKCA,NTM,NTRK3,RYR3,NKAIN3,NRG3,TRPM3,SFXN5,GFAP,GLIS3,ABLIM1,MGAT4C,PITPNC1,HPSE2,DCLK2,MACF1,GPM6A,NAV2,KALRN,RORA,PARD3,SLC1A2,SORBS1,SYNE1,CDH20,LRP1B,GPC5,ADCY2,NDRG2,LSAMP,ERBB4,NRXN1,SLC4A4,NPAS3,NTRK2,SOX5,ATP1A2,TNC,PSD2,CTNND2
1.826e-06	-13.21	lung-right_upper_lobe-carcinoma-adenocarcinoma	COSMIC cancer mutations	lung-right_upper_lobe-carcinoma-adenocarcinoma	10376	45	16828	49	CTNND2,PSD2,TNC,ATP1A2,SOX5,NTRK2,SLC4A4,NPAS3,NRXN1,ERBB4,LSAMP,NDRG2,ADCY2,GPC5,LRP1B,CDH20,SYNE1,SORBS1,SLC1A2,PARD3,RORA,KALRN,GPM6A,NAV2,MACF1,DCLK2,HPSE2,PITPNC1,MGAT4C,ABLIM1,GLIS3,GFAP,TRPM3,SFXN5,NRG3,NKAIN3,RYR3,NTRK3,PRKCA,NTM,DGKG,FMN2,NEBL,RFX4,DTNA
1.926e-06	-13.16	central nervous system development	biological process	GO:0007417	995	13	18204	50	NDRG2,RFX4,RORA,NRG3,ATP1A2,DCLK2,MSI2,NTRK2,SLC1A2,CTNNA2,NAV2,ERBB4,GFAP
2.070e-06	-13.09	LCK (LCK proto-oncogene, Src family tyrosine kinase)	protein interactions	3932	455	9	19454	50	DTNA,PRKCA,CTNND2,ERBB4,FMN2,KALRN,CAMK2G,MACF1,PARD3
2.123e-06	-13.06	plasma membrane bounded cell projection	cellular component	GO:0120025	2285	19	19108	50	MACF1,PSD2,CAMK2G,NTRK3,NTRK2,FMN2,ADCY2,PRKCA,DTNA,ATP1A2,CTNNA2,NDRG2,SYNE1,CTNND2,PARD3,ABLIM1,SLC1A2,GPM6A,GFAP
2.277e-06	-12.99	bone-humerus-other-chondroblastoma	COSMIC cancer mutations	bone-humerus-other-chondroblastoma	301	8	16828	49	GPC5,LRP1B,ADCY2,GPM6A,FMN2,SOX5,NKAIN3,SFXN5
2.359e-06	-12.96	upper_aerodigestive_tract-mouth-carcinoma	COSMIC cancer mutations	upper_aerodigestive_tract-mouth-carcinoma	6426	35	16828	49	SOX5,TNC,CTNND2,PSD2,NDRG2,ADCY2,GPC5,CDH20,LRP1B,SLC4A4,NPAS3,ERBB4,HPSE2,PITPNC1,MGAT4C,ABLIM1,KALRN,RORA,GPM6A,NAV2,MACF1,PARD3,SYNE1,SORBS1,SLC1A2,RFX4,NTRK3,RYR3,NTM,DGKG,FMN2,GFAP,SFXN5,TRPM3,NRG3
2.609e-06	-12.86	neuron development	biological process	GO:0048666	859	12	18204	50	PARD3,GPM6A,NTM,GFAP,DGKG,CTNNA2,CTNND2,NTRK2,DCLK2,NRXN1,KALRN,TNC
3.025e-06	-12.71	scalp	COSMIC cancer mutations	scalp	2110	19	16828	49	TNC,ATP1A2,SORBS1,SYNE1,MACF1,CAMK2G,SOX5,RORA,LSAMP,ERBB4,GFAP,SLC4A4,NRXN1,NEBL,GPC5,FMN2,RPS6KA2,NTRK3,NTM
3.130e-06	-12.67	humerus	COSMIC cancer mutations	humerus	546	10	16828	49	SOX5,KALRN,FMN2,GPM6A,NEBL,ADCY2,GPC5,LRP1B,SFXN5,NKAIN3
3.587e-06	-12.54	multicellular organismal process	biological process	GO:0032501	6177	33	18204	50	RFX4,PRKCA,ABLIM1,DCLK2,ATP1A2,NRG3,NRXN1,RORA,CTNNA2,CTNND2,CDH20,LSAMP,NTRK3,PARD3,DTNA,GPM6A,NEBL,SOX5,RYR3,NDRG2,KALRN,TNC,NAV2,SYNE1,SLC1A2,NTRK2,MSI2,NTM,GFAP,DGKG,SLC4A4,CAMK2G,ERBB4
3.650e-06	-12.52	MAPT (microtubule associated protein tau)	protein interactions	4137	948	12	19454	50	LSAMP,NDRG2,CTNND2,PRKCA,ABLIM1,NEBL,ATP1A2,SORBS1,SLC1A2,GPM6A,CTNNA2,NTM
5.140e-06	-12.18	neuron projection	cellular component	GO:0043005	1331	14	19108	50	CTNND2,SYNE1,DTNA,NDRG2,CTNNA2,ATP1A2,ADCY2,NTRK2,NTRK3,CAMK2G,PSD2,GPM6A,SLC1A2,PARD3
5.182e-06	-12.17	FRS2 (fibroblast growth factor receptor substrate 2)	protein interactions	10818	98	5	19454	50	NTRK2,NTRK3,PARD3,SORBS1,RPS6KA2
6.215e-06	-11.99	upper_aerodigestive_tract	COSMIC cancer mutations	upper_aerodigestive_tract	13181	49	16828	49	SLC14A1,PARD3,MSI2,SYNE1,PITPNC1,MGAT4C,KALRN,DCLK2,NKAIN3,SFXN5,GLIS3,NRG3,DTNA,PRKCA,NTM,RYR3,RPS6KA2,FMN2,DGKG,ATP1A2,PSD2,CAMK2G,NRXN1,SLC4A4,ERBB4,NDRG2,LRP1B,GPC5,ADCY2,SLC1A2,SORBS1,HPSE2,ABLIM1,RORA,MACF1,GPM6A,NAV2,TRPM3,GFAP,RFX4,NEBL,NTRK3,TNC,CTNND2,SOX5,NTRK2,LSAMP,NPAS3,CDH20
6.519e-06	-11.94	cell junction	cellular component	GO:0030054	2224	18	19108	50	CTNND2,SORBS1,ATP1A2,CTNNA2,DTNA,SYNE1,NTRK2,KALRN,RPS6KA2,PSD2,NRXN1,SLC1A2,ERBB4,GPM6A,NRG3,TNC,CDH20,PARD3
6.705e-06	-11.91	carcinoid-endocrine_tumour	COSMIC cancer mutations	carcinoid-endocrine_tumour	7752	38	16828	49	RFX4,NEBL,PRKCA,NTRK3,RYR3,RPS6KA2,FMN2,DGKG,NKAIN3,TRPM3,SFXN5,GLIS3,NRG3,HPSE2,ABLIM1,RORA,KALRN,DCLK2,MACF1,NAV2,GPM6A,PARD3,SYNE1,SLC1A2,CDH20,LRP1B,GPC5,ADCY2,LSAMP,SLC4A4,ERBB4,SOX5,CAMK2G,NTRK2,ATP1A2,TNC,PSD2,CTNND2
6.961e-06	-11.88	Protein_kinase_ATP_BS	interpro domains	IPR017441	377	8	18521	50	NTRK3,ERBB4,PRKCA,RPS6KA2,CAMK2G,KALRN,NTRK2,DCLK2
7.657e-06	-11.78	autonomic_ganglia-neuroblastoma	COSMIC cancer mutations	autonomic_ganglia-neuroblastoma	3970	26	16828	49	PITPNC1,KALRN,MACF1,NAV2,GPM6A,PARD3,SYNE1,SLC1A2,RFX4,NEBL,NTRK3,RYR3,DGKG,FMN2,GLIS3,CAMK2G,NTRK2,ATP1A2,TNC,PSD2,CTNND2,LRP1B,ADCY2,SLC4A4,NPAS3,ERBB4
7.694e-06	-11.78	neuroblastoma	COSMIC cancer mutations	neuroblastoma	3971	26	16828	49	NTRK2,CAMK2G,PSD2,CTNND2,ATP1A2,TNC,LRP1B,ADCY2,NPAS3,SLC4A4,ERBB4,KALRN,MACF1,GPM6A,NAV2,PITPNC1,SYNE1,SLC1A2,PARD3,NTRK3,RYR3,FMN2,DGKG,RFX4,NEBL,GLIS3
7.914e-06	-11.75	developmental process	biological process	GO:0032502	5716	31	18204	50	CAMK2G,ERBB4,GFAP,DGKG,NTM,SLC1A2,NTRK2,MSI2,NAV2,SYNE1,TNC,KALRN,NDRG2,SOX5,NEBL,NTRK3,GPM6A,PARD3,LSAMP,CDH20,CTNND2,CTNNA2,NRXN1,RORA,NRG3,DCLK2,FMN2,ATP1A2,ABLIM1,PRKCA,RFX4
8.070e-06	-11.73	skin-face-carcinoma-squamous_cell_carcinoma	COSMIC cancer mutations	skin-face-carcinoma-squamous_cell_carcinoma	2036	18	16828	49	LSAMP,GFAP,TRPM3,ERBB4,NRG3,NEBL,GPC5,LRP1B,FMN2,RPS6KA2,PARD3,MSI2,SYNE1,ABLIM1,RORA,NAV2,GPM6A,MACF1
9.076e-06	-11.61	autonomic_ganglia	COSMIC cancer mutations	autonomic_ganglia	4005	26	16828	49	SLC1A2,SYNE1,PARD3,MACF1,GPM6A,NAV2,KALRN,PITPNC1,GLIS3,DGKG,FMN2,NTRK3,RYR3,RFX4,NEBL,PSD2,CTNND2,ATP1A2,TNC,NTRK2,CAMK2G,ERBB4,SLC4A4,NPAS3,LRP1B,ADCY2
9.407e-06	-11.57	bone-tibia-other-chondroblastoma	COSMIC cancer mutations	bone-tibia-other-chondroblastoma	98	5	16828	49	GPM6A,CTNND2,NKAIN3,LRP1B,LSAMP
9.576e-06	-11.56	basal_(triple-negative)_carcinoma	COSMIC cancer mutations	basal_(triple-negative)_carcinoma	2981	22	16828	49	KALRN,MACF1,NAV2,PARD3,MSI2,SYNE1,NEBL,PRKCA,NTM,NTRK3,RPS6KA2,FMN2,TRPM3,NRG3,NTRK2,ATP1A2,NDRG2,LRP1B,ADCY2,SLC4A4,NPAS3,ERBB4
9.576e-06	-11.56	breast-carcinoma-basal_(triple-negative)_carcinoma	COSMIC cancer mutations	breast-carcinoma-basal_(triple-negative)_carcinoma	2981	22	16828	49	MACF1,NTRK2,NAV2,KALRN,SYNE1,MSI2,ATP1A2,PARD3,RPS6KA2,FMN2,PRKCA,NTM,NTRK3,LRP1B,ADCY2,NEBL,NDRG2,NRG3,ERBB4,TRPM3,SLC4A4,NPAS3
9.764e-06	-11.54	telencephalon development	biological process	GO:0021537	276	7	18204	50	ERBB4,DCLK2,ATP1A2,NRG3,NTRK2,SLC1A2,RFX4
1.167e-05	-11.36	oesophagus-carcinoma-squamous_cell_carcinoma	COSMIC cancer mutations	oesophagus-carcinoma-squamous_cell_carcinoma	6486	34	16828	49	NDRG2,ADCY2,GPC5,LRP1B,SLC4A4,NPAS3,NRXN1,ERBB4,SOX5,CTNND2,PSD2,TNC,ATP1A2,RYR3,PRKCA,FMN2,RPS6KA2,NEBL,GLIS3,SFXN5,TRPM3,NRG3,KALRN,GPM6A,NAV2,DCLK2,MACF1,HPSE2,PITPNC1,MGAT4C,ABLIM1,SYNE1,SORBS1,PARD3
1.174e-05	-11.35	superficial_spreading	COSMIC cancer mutations	superficial_spreading	1110	13	16828	49	SLC4A4,ERBB4,LRP1B,ADCY2,NTM,NTRK3,TNC,SYNE1,CTNND2,SORBS1,MGAT4C,KALRN,MACF1
1.215e-05	-11.32	oesophagus-middle_third-carcinoma-squamous_cell_carcinoma	COSMIC cancer mutations	oesophagus-middle_third-carcinoma-squamous_cell_carcinoma	3531	24	16828	49	SYNE1,PARD3,NAV2,GPM6A,MACF1,ABLIM1,HPSE2,NRG3,GFAP,TRPM3,FMN2,DGKG,RPS6KA2,NTRK3,RYR3,NEBL,CTNND2,TNC,ATP1A2,SOX5,SLC4A4,ADCY2,LRP1B,GPC5
1.227e-05	-11.31	middle_third	COSMIC cancer mutations	middle_third	3533	24	16828	49	TRPM3,GFAP,NRG3,NEBL,RYR3,NTRK3,RPS6KA2,DGKG,FMN2,PARD3,SYNE1,HPSE2,ABLIM1,MACF1,NAV2,GPM6A,SLC4A4,LRP1B,GPC5,ADCY2,ATP1A2,TNC,CTNND2,SOX5
1.229e-05	-11.31	TIAM1 (TIAM Rac1 associated GEF 1)	protein interactions	7074	201	6	19454	50	PARD3,ATP1A2,RYR3,DTNA,CAMK2G,PRKCA
1.331e-05	-11.23	adenoid_cystic_carcinoma	COSMIC cancer mutations	adenoid_cystic_carcinoma	1123	13	16828	49	RPS6KA2,NTRK3,RYR3,PRKCA,LRP1B,ERBB4,NAV2,NTRK2,CAMK2G,RORA,MGAT4C,CTNND2,SYNE1
1.548e-05	-11.08	salivary_gland	COSMIC cancer mutations	salivary_gland	1139	13	16828	49	RPS6KA2,PRKCA,RYR3,NTRK3,LRP1B,ERBB4,CAMK2G,NTRK2,NAV2,RORA,MGAT4C,SYNE1,CTNND2
1.611e-05	-11.04	face	COSMIC cancer mutations	face	2139	18	16828	49	MSI2,PARD3,SYNE1,ABLIM1,MACF1,GPM6A,NAV2,RORA,LSAMP,ERBB4,NRG3,TRPM3,GFAP,GPC5,LRP1B,NEBL,RPS6KA2,FMN2
1.786e-05	-10.93	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-follicular_lymphoma	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-follicular_lymphoma	981	12	16828	49	LSAMP,PARD3,NKAIN3,CTNND2,NRG3,HPSE2,LRP1B,GPC5,ADCY2,RORA,PRKCA,SOX5
1.850e-05	-10.90	FLOT1 (flotillin 1)	protein interactions	10211	453	8	19454	50	ABLIM1,DTNA,FMN2,MACF1,SORBS1,PARD3,SOX5,SLC14A1
2.030e-05	-10.80	adenoma	COSMIC cancer mutations	adenoma	2873	21	16828	49	GPM6A,MACF1,NTRK2,DCLK2,SOX5,KALRN,HPSE2,CTNND2,SYNE1,PARD3,TNC,RYR3,PRKCA,ADCY2,NEBL,GPC5,CDH20,LRP1B,ERBB4,NPAS3,TRPM3
2.139e-05	-10.75	NTRK	interpro domains	IPR020777	3	2	18521	50	NTRK2,NTRK3
2.139e-05	-10.75	NTRK_LRRCT	interpro domains	IPR031635	3	2	18521	50	NTRK2,NTRK3
2.224e-05	-10.71	LRRCT_2	pfam domains	PF16920	3	2	17795	49	NTRK3,NTRK2
2.258e-05	-10.70	brain development	biological process	GO:0007420	724	10	18204	50	CTNNA2,RFX4,NDRG2,SLC1A2,NTRK2,DCLK2,ATP1A2,NRG3,RORA,ERBB4
2.529e-05	-10.59	regulation of neuron projection development	biological process	GO:0010975	443	8	18204	50	NTRK2,CTNNA2,MACF1,SYNE1,CAMK2G,DGKG,GFAP,NTRK3
2.792e-05	-10.49	Ig_I-set	interpro domains	IPR013098	132	5	18521	50	NTRK3,LSAMP,NTM,NTRK2,KALRN
2.908e-05	-10.45	bone	COSMIC cancer mutations	bone	8157	38	16828	49	LRP1B,GPC5,ADCY2,NDRG2,ERBB4,NRXN1,SLC4A4,NPAS3,LSAMP,CAMK2G,NTRK2,SOX5,PSD2,CTNND2,ATP1A2,TNC,DGKG,FMN2,RYR3,NTRK3,DTNA,NEBL,NRG3,SFXN5,TRPM3,GLIS3,NKAIN3,DCLK2,MACF1,GPM6A,NAV2,RORA,KALRN,ABLIM1,HPSE2,SORBS1,SYNE1,PARD3
2.973e-05	-10.42	lymphoid_neoplasm	COSMIC cancer mutations	lymphoid_neoplasm	12233	47	16828	49	PITPNC1,MGAT4C,KALRN,DCLK2,PARD3,MSI2,SYNE1,DTNA,PRKCA,NTM,RYR3,RPS6KA2,FMN2,DGKG,NKAIN3,SFXN5,GLIS3,NRG3,CAMK2G,ATP1A2,PSD2,GPC5,LRP1B,ADCY2,NRXN1,SLC4A4,ERBB4,HPSE2,ABLIM1,RORA,MACF1,GPM6A,NAV2,SLC1A2,SORBS1,RFX4,NEBL,NTRK3,TRPM3,GFAP,SOX5,NTRK2,TNC,CTNND2,CDH20,LSAMP,NPAS3
2.978e-05	-10.42	salivary_gland-parotid-carcinoma-adenoid_cystic_carcinoma	COSMIC cancer mutations	salivary_gland-parotid-carcinoma-adenoid_cystic_carcinoma	561	9	16828	49	SYNE1,ERBB4,LRP1B,PRKCA,NTRK3,RYR3,CAMK2G,RPS6KA2,NTRK2
2.991e-05	-10.42	cell differentiation	biological process	GO:0030154	3645	23	18204	50	NDRG2,TNC,KALRN,NAV2,SYNE1,MSI2,NTRK2,NTM,ERBB4,CAMK2G,DGKG,GFAP,FMN2,DCLK2,RORA,NRXN1,CTNND2,CTNNA2,NEBL,GPM6A,PARD3,NTRK3,SOX5
3.032e-05	-10.40	cellular developmental process	biological process	GO:0048869	3648	23	18204	50	NDRG2,DCLK2,FMN2,TNC,KALRN,NRXN1,RORA,CTNND2,NAV2,SYNE1,CTNNA2,NTRK2,MSI2,NTM,NEBL,NTRK3,GPM6A,PARD3,CAMK2G,ERBB4,SOX5,GFAP,DGKG
3.042e-05	-10.40	PROTEIN_KINASE_ATP	prosite domains	PS00107	377	8	12186	41	RPS6KA2,ERBB4,NTRK2,DCLK2,CAMK2G,NTRK3,PRKCA,KALRN
3.055e-05	-10.40	I-set	pfam domains	PF07679	132	5	17795	49	NTRK2,NTRK3,KALRN,NTM,LSAMP
3.248e-05	-10.33	SLC6A15 (solute carrier family 6 member 15)	protein interactions	55117	143	5	19454	50	RPS6KA2,SFXN5,NTRK2,PARD3,NTRK3
3.322e-05	-10.31	SHC1 events in ERBB2 signaling	REACTOME pathways	R-HSA-1250196	22	3	10285	30	PRKCA,NRG3,ERBB4
3.354e-05	-10.30	NTKRECEPTOR	prints domains	PR01939	3	2	5227	18	NTRK3,NTRK2
3.484e-05	-10.26	OCLN (occludin)	protein interactions	100506658	495	8	19454	50	PARD3,MACF1,FMN2,NTRK2,RPS6KA2,DTNA,ABLIM1,PRKCA
3.600e-05	-10.23	Spectrin_repeat	interpro domains	IPR002017	24	3	18521	50	KALRN,SYNE1,MACF1
3.762e-05	-10.19	parotid	COSMIC cancer mutations	parotid	578	9	16828	49	SYNE1,ERBB4,PRKCA,NTRK3,RYR3,RPS6KA2,CAMK2G,NTRK2,LRP1B
3.813e-05	-10.17	Spectrin	pfam domains	PF00435	24	3	17795	49	MACF1,KALRN,SYNE1
3.961e-05	-10.14	Prot_kinase_dom	interpro domains	IPR000719	480	8	18521	50	NTRK3,ERBB4,RPS6KA2,PRKCA,CAMK2G,DCLK2,NTRK2,KALRN
3.991e-05	-10.13	head development	biological process	GO:0060322	774	10	18204	50	NDRG2,SLC1A2,NTRK2,CTNNA2,RFX4,RORA,ERBB4,DCLK2,ATP1A2,NRG3
4.550e-05	-10.00	Htt (huntingtin)	protein interactions	15194	77	4	19454	50	GPM6A,NTM,GFAP,LSAMP
4.687e-05	-9.97	lung-carcinoma-small_cell_carcinoma	COSMIC cancer mutations	lung-carcinoma-small_cell_carcinoma	9908	42	16828	49	NEBL,DTNA,RFX4,RYR3,NTRK3,NTM,PRKCA,DGKG,FMN2,RPS6KA2,NKAIN3,TRPM3,NRG3,HPSE2,PITPNC1,MGAT4C,ABLIM1,KALRN,RORA,NAV2,GPM6A,MACF1,DCLK2,SLC14A1,PARD3,MSI2,SYNE1,SORBS1,NDRG2,LRP1B,GPC5,CDH20,SLC4A4,NPAS3,NRXN1,ERBB4,SOX5,NTRK2,CAMK2G,TNC,ATP1A2,CTNND2
4.765e-05	-9.95	small_cell_carcinoma	COSMIC cancer mutations	small_cell_carcinoma	9913	42	16828	49	ERBB4,SLC4A4,NPAS3,NRXN1,CDH20,GPC5,LRP1B,NDRG2,TNC,ATP1A2,CTNND2,NTRK2,CAMK2G,SOX5,NKAIN3,NRG3,TRPM3,NEBL,RFX4,DTNA,DGKG,FMN2,RPS6KA2,NTRK3,RYR3,PRKCA,NTM,MSI2,SLC14A1,PARD3,SORBS1,SYNE1,MGAT4C,ABLIM1,HPSE2,PITPNC1,GPM6A,NAV2,MACF1,DCLK2,KALRN,RORA
4.784e-05	-9.95	Signalling by NGF	REACTOME pathways	R-HSA-166520	477	8	10285	30	NTRK2,KALRN,ERBB4,RPS6KA2,NRG3,PRKCA,ADCY2,CAMK2G
4.933e-05	-9.92	Nuclear signaling by ERBB4	REACTOME pathways	R-HSA-1251985	25	3	10285	30	NRG3,ERBB4,GFAP
5.002e-05	-9.90	LRRC7 (leucine rich repeat containing 7)	protein interactions	57554	28	3	19454	50	CAMK2G,ERBB4,CTNND2
5.429e-05	-9.82	skin-head_neck-malignant_melanoma-superficial_spreading	COSMIC cancer mutations	skin-head_neck-malignant_melanoma-superficial_spreading	923	11	16828	49	TNC,ERBB4,SORBS1,SYNE1,CTNND2,LRP1B,ADCY2,MGAT4C,MACF1,KALRN,NTRK3
5.570e-05	-9.80	cell development	biological process	GO:0048468	2236	17	18204	50	DGKG,GFAP,ERBB4,PARD3,GPM6A,NEBL,NTM,MSI2,NTRK2,CTNNA2,CTNND2,RORA,KALRN,NRXN1,TNC,FMN2,DCLK2
6.620e-05	-9.62	skin-arm-malignant_melanoma	COSMIC cancer mutations	skin-arm-malignant_melanoma	1308	13	16828	49	KALRN,MACF1,NAV2,SYNE1,SORBS1,ATP1A2,NTM,PRKCA,LRP1B,TRPM3,SLC4A4,NPAS3,ERBB4
6.710e-05	-9.61	bronchioloalveolar_adenocarcinoma	COSMIC cancer mutations	bronchioloalveolar_adenocarcinoma	778	10	16828	49	ADCY2,SOX5,NTRK3,PRKCA,CAMK2G,DCLK2,RPS6KA2,NTRK2,CTNND2,ERBB4
6.710e-05	-9.61	lung-carcinoma-bronchioloalveolar_adenocarcinoma	COSMIC cancer mutations	lung-carcinoma-bronchioloalveolar_adenocarcinoma	778	10	16828	49	CTNND2,ERBB4,ADCY2,SOX5,NTRK3,PRKCA,RPS6KA2,DCLK2,NTRK2,CAMK2G
7.140e-05	-9.55	Spectrin/alpha-actinin	interpro domains	IPR018159	30	3	18521	50	KALRN,SYNE1,MACF1
7.147e-05	-9.55	neurotrophin receptor activity	molecular function	GO:0005030	5	2	18094	49	NTRK3,NTRK2
7.242e-05	-9.53	Kinase-like_dom_sf	interpro domains	IPR011009	523	8	18521	50	DCLK2,NTRK2,KALRN,CAMK2G,ERBB4,PRKCA,RPS6KA2,NTRK3
7.268e-05	-9.53	regulation of plasma membrane bounded cell projection organization	biological process	GO:0120035	666	9	18204	50	NTRK2,CTNNA2,SYNE1,MACF1,CAMK2G,DGKG,GFAP,GPM6A,NTRK3
7.355e-05	-9.52	D-aspartate import across plasma membrane	biological process	GO:0070779	5	2	18204	50	GFAP,SLC1A2
7.355e-05	-9.52	D-aspartate transmembrane transport	biological process	GO:0070777	5	2	18204	50	GFAP,SLC1A2
7.377e-05	-9.51	testis-germ_cell_tumour-non_seminoma	COSMIC cancer mutations	testis-germ_cell_tumour-non_seminoma	487	8	16828	49	ERBB4,MACF1,CAMK2G,NTRK2,RPS6KA2,DCLK2,NTRK3,PRKCA
7.654e-05	-9.48	upper_aerodigestive_tract-larynx-carcinoma-squamous_cell_carcinoma	COSMIC cancer mutations	upper_aerodigestive_tract-larynx-carcinoma-squamous_cell_carcinoma	1946	16	16828	49	MGAT4C,HPSE2,MACF1,GPM6A,RORA,SOX5,SYNE1,LRP1B,NEBL,FMN2,NTRK3,RYR3,ERBB4,NRXN1,SLC4A4,NPAS3
7.670e-05	-9.48	synapse	cellular component	GO:0045202	1473	13	19108	50	PSD2,RPS6KA2,KALRN,NTRK2,SYNE1,DTNA,ATP1A2,CTNND2,NRG3,ERBB4,GPM6A,SLC1A2,NRXN1
7.695e-05	-9.47	skin-scalp-malignant_melanoma	COSMIC cancer mutations	skin-scalp-malignant_melanoma	634	9	16828	49	NEBL,NTM,CAMK2G,RPS6KA2,FMN2,TNC,SYNE1,ERBB4,SORBS1
7.750e-05	-9.47	larynx	COSMIC cancer mutations	larynx	1948	16	16828	49	NRXN1,SLC4A4,NPAS3,ERBB4,NTRK3,RYR3,FMN2,LRP1B,NEBL,SYNE1,RORA,SOX5,MACF1,GPM6A,HPSE2,MGAT4C
7.919e-05	-9.44	arm	COSMIC cancer mutations	arm	1331	13	16828	49	PRKCA,NTM,LRP1B,ERBB4,TRPM3,NPAS3,SLC4A4,MACF1,NAV2,KALRN,SORBS1,SYNE1,ATP1A2
7.923e-05	-9.44	non_seminoma	COSMIC cancer mutations	non_seminoma	492	8	16828	49	ERBB4,CAMK2G,RPS6KA2,NTRK2,DCLK2,MACF1,NTRK3,PRKCA
7.933e-05	-9.44	mast_cell_neoplasm	COSMIC cancer mutations	mast_cell_neoplasm	248	6	16828	49	GPC5,ADCY2,HPSE2,NRG3,ERBB4,NPAS3
7.933e-05	-9.44	haematopoietic_and_lymphoid_tissue-haematopoietic_neoplasm-mast_cell_neoplasm	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue-haematopoietic_neoplasm-mast_cell_neoplasm	248	6	16828	49	NPAS3,ERBB4,NRG3,HPSE2,GPC5,ADCY2
8.096e-05	-9.42	phosphotransferase activity, alcohol group as acceptor	molecular function	GO:0016773	686	9	18094	49	NTRK2,RPS6KA2,NTRK3,CAMK2G,DGKG,DCLK2,KALRN,PRKCA,ERBB4
8.117e-05	-9.42	skin-trunk-malignant_melanoma	COSMIC cancer mutations	skin-trunk-malignant_melanoma	2647	19	16828	49	HPSE2,MGAT4C,KALRN,SOX5,ATP1A2,SLC14A1,TNC,PARD3,SYNE1,CTNND2,LRP1B,CDH20,NEBL,RYR3,RPS6KA2,LSAMP,NRXN1,NRG3,ERBB4
8.255e-05	-9.40	NTM (neurotrimin)	protein interactions	50863	33	3	19454	50	LSAMP,NTM,GPM6A
8.559e-05	-9.37	plasma membrane region	cellular component	GO:0098590	1278	12	19108	50	SLC4A4,SLC1A2,GPM6A,ERBB4,NRXN1,PARD3,ATP1A2,SYNE1,SORBS1,MACF1,PSD2,SLC14A1
8.670e-05	-9.35	papillary_renal_cell_carcinoma	COSMIC cancer mutations	papillary_renal_cell_carcinoma	6364	32	16828	49	CTNND2,PSD2,ATP1A2,SOX5,CAMK2G,NTRK2,SLC4A4,NRXN1,ERBB4,ADCY2,GPC5,LRP1B,SYNE1,PARD3,RORA,KALRN,NAV2,MACF1,DCLK2,HPSE2,PITPNC1,ABLIM1,TRPM3,NRG3,NTRK3,RYR3,NTM,PRKCA,FMN2,DGKG,RPS6KA2,RFX4
8.670e-05	-9.35	kidney-carcinoma-papillary_renal_cell_carcinoma	COSMIC cancer mutations	kidney-carcinoma-papillary_renal_cell_carcinoma	6364	32	16828	49	TRPM3,NRG3,RFX4,PRKCA,NTM,RYR3,NTRK3,RPS6KA2,DGKG,FMN2,PARD3,SYNE1,PITPNC1,HPSE2,ABLIM1,RORA,KALRN,MACF1,DCLK2,NAV2,NRXN1,SLC4A4,ERBB4,GPC5,LRP1B,ADCY2,ATP1A2,PSD2,CTNND2,SOX5,NTRK2,CAMK2G
8.705e-05	-9.35	urinary_tract-bladder-carcinoma-transitional_cell_carcinoma	COSMIC cancer mutations	urinary_tract-bladder-carcinoma-transitional_cell_carcinoma	6040	31	16828	49	FMN2,DGKG,DTNA,RFX4,NEBL,TRPM3,SFXN5,GLIS3,NRG3,KALRN,MACF1,NAV2,GPM6A,HPSE2,ABLIM1,MGAT4C,SYNE1,SORBS1,PARD3,CDH20,LRP1B,GPC5,ADCY2,NRXN1,SLC4A4,ERBB4,NTRK2,CAMK2G,PSD2,ATP1A2,TNC
8.767e-05	-9.34	transitional_cell_carcinoma	COSMIC cancer mutations	transitional_cell_carcinoma	6042	31	16828	49	NEBL,RFX4,DTNA,DGKG,FMN2,NRG3,GLIS3,SFXN5,TRPM3,MGAT4C,ABLIM1,HPSE2,NAV2,GPM6A,MACF1,KALRN,PARD3,SORBS1,SYNE1,ADCY2,GPC5,LRP1B,CDH20,ERBB4,SLC4A4,NRXN1,NTRK2,CAMK2G,TNC,ATP1A2,PSD2
8.816e-05	-9.34	regulation of cell projection organization	biological process	GO:0031344	683	9	18204	50	MACF1,SYNE1,CTNNA2,NTRK2,NTRK3,GPM6A,GFAP,DGKG,CAMK2G
9.721e-05	-9.24	NGF signalling via TRKA from the plasma membrane	REACTOME pathways	R-HSA-187037	387	7	10285	30	NRG3,RPS6KA2,ERBB4,NTRK2,CAMK2G,ADCY2,PRKCA
1.011e-04	-9.20	PRNP (prion protein (Kanno blood group))	protein interactions	5621	1118	11	19454	50	GPM6A,SORBS1,CAMK2G,MACF1,TNC,ATP1A2,ABLIM1,TRPM3,SLC4A4,MSI2,LSAMP
1.101e-04	-9.11	ERBB4-ERBB4 signaling pathway	biological process	GO:0038138	6	2	18204	50	NRG3,ERBB4
1.101e-04	-9.11	D-amino acid transport	biological process	GO:0042940	6	2	18204	50	SLC1A2,GFAP
1.108e-04	-9.11	ovary-carcinoma-clear_cell_carcinoma	COSMIC cancer mutations	ovary-carcinoma-clear_cell_carcinoma	665	9	16828	49	ERBB4,NDRG2,LRP1B,NTRK3,PRKCA,RPS6KA2,DCLK2,NTRK2,CAMK2G
1.118e-04	-9.10	pancreas-carcinoma-adenocarcinoma	COSMIC cancer mutations	pancreas-carcinoma-adenocarcinoma	517	8	16828	49	LRP1B,GPC5,NEBL,HPSE2,MACF1,DCLK2,TNC,SYNE1
1.123e-04	-9.09	skin-mucosal-malignant_melanoma	COSMIC cancer mutations	skin-mucosal-malignant_melanoma	2009	16	16828	49	PSD2,SYNE1,CTNND2,SORBS1,ATP1A2,PARD3,TNC,RORA,NAV2,ABLIM1,MGAT4C,ERBB4,NRG3,FMN2,LRP1B,NEBL
1.123e-04	-9.09	mucosal	COSMIC cancer mutations	mucosal	2009	16	16828	49	RORA,NAV2,ABLIM1,MGAT4C,SYNE1,PSD2,CTNND2,SORBS1,ATP1A2,PARD3,TNC,FMN2,LRP1B,NEBL,NRG3,ERBB4
1.136e-04	-9.08	haematopoietic_neoplasm	COSMIC cancer mutations	haematopoietic_neoplasm	11082	44	16828	49	NKAIN3,GLIS3,SFXN5,NRG3,DTNA,RYR3,PRKCA,NTM,DGKG,FMN2,RPS6KA2,PARD3,SLC14A1,MSI2,SYNE1,KALRN,DCLK2,SLC4A4,NRXN1,ERBB4,ADCY2,GPC5,LRP1B,ATP1A2,PSD2,CAMK2G,GFAP,TRPM3,NEBL,RFX4,NTRK3,SLC1A2,HPSE2,ABLIM1,RORA,NAV2,MACF1,LSAMP,NPAS3,CDH20,TNC,CTNND2,SOX5,NTRK2
1.160e-04	-9.06	clear_cell_carcinoma	COSMIC cancer mutations	clear_cell_carcinoma	669	9	16828	49	ERBB4,NDRG2,LRP1B,NTRK3,PRKCA,DCLK2,CAMK2G,NTRK2,RPS6KA2
1.166e-04	-9.06	CDH1 (cadherin 1)	protein interactions	999	757	9	19454	50	NAV2,NDRG2,CTNND2,ABLIM1,NEBL,PARD3,MACF1,SORBS1,CTNNA2
1.167e-04	-9.06	Transferase(Phosphotransferase) domain 1	gene3d domains	1.10.510.10	490	8	14470	45	CAMK2G,RPS6KA2,DCLK2,NTRK2,KALRN,ERBB4,NTRK3,PRKCA
1.174e-04	-9.05	forebrain development	biological process	GO:0030900	408	7	18204	50	NTRK2,SLC1A2,RFX4,ERBB4,ATP1A2,DCLK2,NRG3
1.179e-04	-9.05	cell adhesion molecule binding	molecular function	GO:0050839	560	8	18094	49	CTNND2,GFAP,NRXN1,CTNNA2,CDH20,PRKCA,TNC,MACF1
1.219e-04	-9.01	tibia	COSMIC cancer mutations	tibia	836	10	16828	49	TRPM3,PSD2,CTNND2,LSAMP,NKAIN3,MACF1,GPM6A,NDRG2,ABLIM1,LRP1B
1.293e-04	-8.95	adherens junction	cellular component	GO:0005912	188	5	19108	50	SORBS1,CTNND2,PARD3,CDH20,CTNNA2
1.367e-04	-8.90	follicular_lymphoma	COSMIC cancer mutations	follicular_lymphoma	1209	12	16828	49	HPSE2,SOX5,RORA,PARD3,CTNND2,ADCY2,GPC5,LRP1B,PRKCA,NKAIN3,LSAMP,NRG3
1.394e-04	-8.88	Gastric acid secretion	KEGG pathways	hsa04971	75	4	7161	26	ATP1A2,ADCY2,CAMK2G,PRKCA
1.394e-04	-8.88	Gastric acid secretion	KEGG pathways	ko04971	75	4	7161	26	ATP1A2,ADCY2,PRKCA,CAMK2G
1.426e-04	-8.86	kinase activity	molecular function	GO:0016301	739	9	18094	49	ERBB4,PRKCA,KALRN,CAMK2G,NTRK2,RPS6KA2,NTRK3,DCLK2,DGKG
1.446e-04	-8.84	phosphorylation	biological process	GO:0016310	729	9	18204	50	KALRN,DGKG,CAMK2G,ERBB4,NTRK3,DCLK2,PRKCA,NTRK2,RPS6KA2
1.449e-04	-8.84	protein kinase activity	molecular function	GO:0004672	577	8	18094	49	CAMK2G,NTRK3,NTRK2,RPS6KA2,DCLK2,ERBB4,KALRN,PRKCA
1.476e-04	-8.82	DZIP1 (DAZ interacting zinc finger protein 1)	protein interactions	22873	40	3	19454	50	CAMK2G,NTRK2,PARD3
1.476e-04	-8.82	SHC2 (SHC adaptor protein 2)	protein interactions	25759	40	3	19454	50	ERBB4,NTRK2,NTRK3
1.566e-04	-8.76	actin binding	molecular function	GO:0003779	434	7	18094	49	SYNE1,NEBL,CTNNA2,SORBS1,MACF1,FMN2,ABLIM1
1.597e-04	-8.74	SPEC	smart domains	SM00150	29	3	9717	36	SYNE1,MACF1,KALRN
1.598e-04	-8.74	stomach-carcinoma-diffuse_adenocarcinoma	COSMIC cancer mutations	stomach-carcinoma-diffuse_adenocarcinoma	4383	25	16828	49	MGAT4C,ABLIM1,NAV2,GPM6A,MACF1,KALRN,PARD3,SYNE1,RFX4,DTNA,FMN2,DGKG,RYR3,NTRK3,NRG3,GLIS3,TRPM3,SOX5,TNC,ATP1A2,CTNND2,PSD2,ADCY2,LRP1B,ERBB4
1.598e-04	-8.74	diffuse_adenocarcinoma	COSMIC cancer mutations	diffuse_adenocarcinoma	4383	25	16828	49	TNC,ATP1A2,CTNND2,PSD2,SOX5,ERBB4,ADCY2,LRP1B,PARD3,SYNE1,MGAT4C,ABLIM1,KALRN,GPM6A,NAV2,MACF1,GLIS3,TRPM3,NRG3,RFX4,DTNA,NTRK3,RYR3,FMN2,DGKG
1.608e-04	-8.74	kidney-Wilms_tumour	COSMIC cancer mutations	kidney-Wilms_tumour	545	8	16828	49	ERBB4,PRKCA,NTRK3,CAMK2G,NTRK2,RPS6KA2,DCLK2,FMN2
1.628e-04	-8.72	Wilms_tumour	COSMIC cancer mutations	Wilms_tumour	546	8	16828	49	ERBB4,FMN2,CAMK2G,NTRK2,RPS6KA2,DCLK2,NTRK3,PRKCA
1.658e-04	-8.70	PROTEIN_KINASE_DOM	prosite domains	PS50011	480	8	12186	41	KALRN,PRKCA,NTRK3,CAMK2G,DCLK2,NTRK2,ERBB4,RPS6KA2
1.706e-04	-8.68	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-acute_lymphoblastic_leukaemia	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-acute_lymphoblastic_leukaemia	2081	16	16828	49	ATP1A2,SYNE1,KALRN,SOX5,CAMK2G,NTRK2,DCLK2,GFAP,SLC4A4,ERBB4,LRP1B,DTNA,ADCY2,PRKCA,NTRK3,RPS6KA2
1.716e-04	-8.67	-	gene3d domains	1.20.58.60	35	3	14470	45	SYNE1,MACF1,KALRN
1.762e-04	-8.64	pancreas-carcinoid-endocrine_tumour	COSMIC cancer mutations	pancreas-carcinoid-endocrine_tumour	7250	34	16828	49	SOX5,NTRK2,ATP1A2,TNC,PSD2,CTNND2,CDH20,GPC5,LRP1B,ADCY2,LSAMP,SLC4A4,ERBB4,HPSE2,ABLIM1,RORA,KALRN,MACF1,GPM6A,NAV2,PARD3,SYNE1,SLC1A2,RFX4,NEBL,PRKCA,RYR3,NTRK3,FMN2,DGKG,NKAIN3,SFXN5,GLIS3,NRG3
1.795e-04	-8.63	LHB (luteinizing hormone subunit beta)	protein interactions	3972	8	2	19454	50	NTM,GFAP
1.843e-04	-8.60	lung-left_upper_lobe-carcinoma-adenocarcinoma	COSMIC cancer mutations	lung-left_upper_lobe-carcinoma-adenocarcinoma	556	8	16828	49	ERBB4,SYNE1,SLC4A4,CTNND2,LRP1B,ADCY2,NTRK2,RYR3
1.870e-04	-8.58	membrane	cellular component	GO:0016020	9220	37	19108	50	CAMK2G,NTRK3,MACF1,PRKCA,RYR3,SLC14A1,FMN2,SYNE1,CTNNA2,GPC5,DTNA,HPSE2,CTNND2,CDH20,PARD3,NTM,TNC,GPM6A,ERBB4,SFXN5,SLC4A4,SLC1A2,LSAMP,GFAP,PSD2,MGAT4C,ADCY2,NTRK2,KALRN,ATP1A2,SORBS1,NRG3,DGKG,TRPM3,NKAIN3,NRXN1,LRP1B
1.889e-04	-8.57	left_upper_lobe	COSMIC cancer mutations	left_upper_lobe	558	8	16828	49	ERBB4,SLC4A4,CTNND2,SYNE1,NTRK2,RYR3,ADCY2,LRP1B
1.891e-04	-8.57	skin-extremity-malignant_melanoma	COSMIC cancer mutations	skin-extremity-malignant_melanoma	1875	15	16828	49	PITPNC1,HPSE2,NTRK2,PARD3,TNC,SYNE1,CDH20,LRP1B,NEBL,ADCY2,NTRK3,RYR3,DGKG,FMN2,ERBB4
1.902e-04	-8.57	extremity	COSMIC cancer mutations	extremity	1876	15	16828	49	ERBB4,RYR3,NTRK3,DGKG,FMN2,ADCY2,NEBL,CDH20,LRP1B,SYNE1,TNC,PARD3,NTRK2,HPSE2,PITPNC1
1.943e-04	-8.55	anatomical structure morphogenesis	biological process	GO:0009653	2225	16	18204	50	CTNND2,CTNNA2,NTRK2,CDH20,NEBL,PARD3,GPM6A,ERBB4,SOX5,ABLIM1,PRKCA,NRG3,TNC,NRXN1,KALRN,RORA
1.964e-04	-8.54	SH2D1A (SH2 domain containing 1A)	protein interactions	4068	44	3	19454	50	ERBB4,CAMK2G,LRP1B
1.996e-04	-8.52	beta-catenin binding	molecular function	GO:0008013	107	4	18094	49	RORA,CTNND2,CTNNA2,CDH20
2.037e-04	-8.50	cell adhesion	biological process	GO:0007155	942	10	18204	50	SORBS1,CDH20,PRKCA,LSAMP,CTNNA2,CTNND2,NRXN1,TNC,PARD3,NTM
2.048e-04	-8.49	ERBB4 signaling pathway	biological process	GO:0038130	8	2	18204	50	NRG3,ERBB4
2.226e-04	-8.41	g-Secretase Mediated ErbB4 Signalling Pathway	SMPDB pathways	SMP0089975	7	2	1369	5	PRKCA,ERBB4
2.254e-04	-8.40	Gastrin-CREB signalling pathway via PKC and MAPK	REACTOME pathways	R-HSA-881907	443	7	10285	30	RPS6KA2,KALRN,ERBB4,NRG3,CAMK2G,PRKCA,DGKG
2.265e-04	-8.39	ErbB signaling pathway	KEGG pathways	ko04012	85	4	7161	26	PRKCA,CAMK2G,ERBB4,NRG3
2.265e-04	-8.39	Insulin secretion	KEGG pathways	hsa04911	85	4	7161	26	PRKCA,CAMK2G,ATP1A2,ADCY2
2.265e-04	-8.39	ErbB signaling pathway	KEGG pathways	hsa04012	85	4	7161	26	NRG3,ERBB4,CAMK2G,PRKCA
2.302e-04	-8.38	chromophobe_renal_cell_carcinoma	COSMIC cancer mutations	chromophobe_renal_cell_carcinoma	430	7	16828	49	RPS6KA2,NTRK2,DCLK2,CAMK2G,PRKCA,NTRK3,ERBB4
2.302e-04	-8.38	kidney-carcinoma-chromophobe_renal_cell_carcinoma	COSMIC cancer mutations	kidney-carcinoma-chromophobe_renal_cell_carcinoma	430	7	16828	49	DCLK2,NTRK2,RPS6KA2,CAMK2G,PRKCA,NTRK3,ERBB4
2.304e-04	-8.38	NEGR1 (neuronal growth regulator 1)	protein interactions	257194	9	2	19454	50	LSAMP,NTM
2.304e-04	-8.38	LSAMP (limbic system associated membrane protein)	protein interactions	4045	9	2	19454	50	NTM,LSAMP
2.305e-04	-8.38	testis	COSMIC cancer mutations	testis	733	9	16828	49	ERBB4,SYNE1,RPS6KA2,NTRK2,CAMK2G,MACF1,DCLK2,NTRK3,PRKCA
2.323e-04	-8.37	GFAP (glial fibrillary acidic protein)	protein interactions	2670	217	5	19454	50	NKAIN3,RORA,ABLIM1,PRKCA,GFAP
2.353e-04	-8.35	haematopoietic_and_lymphoid_tissue-haematopoietic_neoplasm-acute_myeloid_leukaemia	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue-haematopoietic_neoplasm-acute_myeloid_leukaemia	10418	42	16828	49	LSAMP,SLC4A4,NPAS3,NRXN1,ERBB4,ADCY2,LRP1B,GPC5,CDH20,TNC,ATP1A2,CTNND2,PSD2,SOX5,NTRK2,CAMK2G,NKAIN3,GFAP,GLIS3,TRPM3,SFXN5,NRG3,NEBL,RFX4,NTRK3,RYR3,NTM,PRKCA,DGKG,FMN2,RPS6KA2,PARD3,SLC14A1,MSI2,SYNE1,SLC1A2,HPSE2,ABLIM1,RORA,KALRN,NAV2,MACF1
2.353e-04	-8.35	acute_myeloid_leukaemia	COSMIC cancer mutations	acute_myeloid_leukaemia	10418	42	16828	49	MSI2,PARD3,SLC14A1,SLC1A2,SYNE1,ABLIM1,HPSE2,MACF1,NAV2,RORA,KALRN,NKAIN3,NRG3,TRPM3,SFXN5,GFAP,GLIS3,RFX4,NEBL,RPS6KA2,DGKG,FMN2,NTM,PRKCA,RYR3,NTRK3,ATP1A2,TNC,PSD2,CTNND2,CAMK2G,NTRK2,SOX5,LSAMP,ERBB4,NRXN1,SLC4A4,NPAS3,CDH20,GPC5,LRP1B,ADCY2
2.443e-04	-8.32	central_nervous_system-cerebellum-glioma-astrocytoma_Grade_I	COSMIC cancer mutations	central_nervous_system-cerebellum-glioma-astrocytoma_Grade_I	105	4	16828	49	LRP1B,GPC5,PARD3,NRG3
2.501e-04	-8.29	postsynapse	cellular component	GO:0098794	646	8	19108	50	CTNND2,ATP1A2,ERBB4,SYNE1,GPM6A,NTRK2,KALRN,PSD2
2.555e-04	-8.27	Signaling by ERBB4	REACTOME pathways	R-HSA-1236394	43	3	10285	30	GFAP,NRG3,ERBB4
2.584e-04	-8.26	actin filament binding	molecular function	GO:0051015	211	5	18094	49	ABLIM1,SYNE1,NEBL,CTNNA2,MACF1
2.601e-04	-8.25	acral_lentiginous	COSMIC cancer mutations	acral_lentiginous	745	9	16828	49	LRP1B,CDH20,MACF1,KALRN,TNC,PARD3,NRG3,ERBB4,SYNE1
2.608e-04	-8.25	axon	cellular component	GO:0030424	650	8	19108	50	PARD3,NTRK3,NTRK2,DTNA,CTNNA2,SLC1A2,NDRG2,GPM6A
2.823e-04	-8.17	Salivary secretion	KEGG pathways	hsa04970	90	4	7161	26	RYR3,PRKCA,ATP1A2,ADCY2
2.823e-04	-8.17	Salivary secretion	KEGG pathways	ko04970	90	4	7161	26	PRKCA,RYR3,ADCY2,ATP1A2
2.889e-04	-8.15	synapse organization	biological process	GO:0050808	333	6	18204	50	CTNND2,GPM6A,NRG3,NRXN1,TNC,ERBB4
2.926e-04	-8.14	Non-integrin membrane-ECM interactions	REACTOME pathways	R-HSA-3000171	45	3	10285	30	PRKCA,NRXN1,TNC
2.977e-04	-8.12	ovary-carcinoma	COSMIC cancer mutations	ovary-carcinoma	933	10	16828	49	ATP1A2,SYNE1,ERBB4,PRKCA,NTRK3,MACF1,DCLK2,CAMK2G,RPS6KA2,NTRK2
2.978e-04	-8.12	VANGL1 (VANGL planar cell polarity protein 1)	protein interactions	81839	229	5	19454	50	NTRK2,PARD3,NTRK3,RPS6KA2,ERBB4
3.069e-04	-8.09	synapse assembly	biological process	GO:0007416	118	4	18204	50	NRXN1,ERBB4,GPM6A,NRG3
3.104e-04	-8.08	breast-carcinoma-lobular_carcinoma	COSMIC cancer mutations	breast-carcinoma-lobular_carcinoma	763	9	16828	49	DCLK2,RPS6KA2,CAMK2G,NTRK2,PRKCA,NTRK3,LRP1B,CDH20,ERBB4
3.104e-04	-8.08	lobular_carcinoma	COSMIC cancer mutations	lobular_carcinoma	763	9	16828	49	ERBB4,DCLK2,CAMK2G,NTRK2,RPS6KA2,NTRK3,PRKCA,CDH20,LRP1B
3.162e-04	-8.06	EPB41L4A (erythrocyte membrane protein band 4.1 like 4A)	protein interactions	64097	127	4	19454	50	PARD3,MACF1,DTNA,ABLIM1
3.188e-04	-8.05	neurotrophin binding	molecular function	GO:0043121	10	2	18094	49	NTRK2,NTRK3
3.212e-04	-8.04	acute_lymphoblastic_leukaemia	COSMIC cancer mutations	acute_lymphoblastic_leukaemia	2197	16	16828	49	GFAP,SLC4A4,ERBB4,ADCY2,LRP1B,DTNA,NTRK3,PRKCA,RPS6KA2,ATP1A2,SYNE1,SOX5,KALRN,DCLK2,NTRK2,CAMK2G
3.231e-04	-8.04	SH2B2 (SH2B adaptor protein 2)	protein interactions	10603	52	3	19454	50	SORBS1,ERBB4,NTRK2
3.267e-04	-8.03	YES1 (YES proto-oncogene 1, Src family tyrosine kinase)	protein interactions	7525	364	6	19454	50	GFAP,CAMK2G,ERBB4,RPS6KA2,SLC14A1,MSI2
3.281e-04	-8.02	neuronal action potential propagation	biological process	GO:0019227	10	2	18204	50	ATP1A2,NTRK2
3.281e-04	-8.02	action potential propagation	biological process	GO:0098870	10	2	18204	50	ATP1A2,NTRK2
3.289e-04	-8.02	ovary-carcinoma-mucinous_carcinoma	COSMIC cancer mutations	ovary-carcinoma-mucinous_carcinoma	456	7	16828	49	ERBB4,DCLK2,NTRK2,RPS6KA2,CAMK2G,PRKCA,NTRK3
3.377e-04	-7.99	mucinous_carcinoma	COSMIC cancer mutations	mucinous_carcinoma	458	7	16828	49	ERBB4,PRKCA,NTRK3,RPS6KA2,NTRK2,CAMK2G,DCLK2
3.468e-04	-7.97	stomach-carcinoma-mixed_intestinal_and_diffuse_adenocarcinoma-unclassifiable	COSMIC cancer mutations	stomach-carcinoma-mixed_intestinal_and_diffuse_adenocarcinoma-unclassifiable	951	10	16828	49	TNC,PARD3,SLC1A2,TRPM3,SYNE1,GPC5,LRP1B,FMN2,MACF1,NTRK3
3.468e-04	-7.97	mixed_intestinal_and_diffuse_adenocarcinoma-unclassifiable	COSMIC cancer mutations	mixed_intestinal_and_diffuse_adenocarcinoma-unclassifiable	951	10	16828	49	FMN2,MACF1,NTRK3,LRP1B,GPC5,SLC1A2,SYNE1,TRPM3,PARD3,TNC
3.474e-04	-7.96	Pancreatic secretion	KEGG pathways	hsa04972	95	4	7161	26	ADCY2,ATP1A2,PRKCA,SLC4A4
3.474e-04	-7.96	Pancreatic secretion	KEGG pathways	ko04972	95	4	7161	26	ADCY2,ATP1A2,PRKCA,SLC4A4
3.508e-04	-7.96	ADCY5 (adenylate cyclase 5)	protein interactions	111	11	2	19454	50	PRKCA,ADCY2
3.613e-04	-7.93	SYNM (synemin)	protein interactions	23336	54	3	19454	50	DTNA,ERBB4,GFAP
3.617e-04	-7.92	Circadian entrainment	KEGG pathways	hsa04713	96	4	7161	26	PRKCA,CAMK2G,RYR3,ADCY2
3.617e-04	-7.92	Circadian entrainment	KEGG pathways	ko04713	96	4	7161	26	RYR3,PRKCA,CAMK2G,ADCY2
3.636e-04	-7.92	interstitial matrix	cellular component	GO:0005614	11	2	19108	50	TNC,NAV2
3.648e-04	-7.92	PI3K events in ERBB4 signaling	REACTOME pathways	R-HSA-1250342	10	2	10285	30	ERBB4,NRG3
3.653e-04	-7.91	ovary-carcinoma-endometrioid_carcinoma	COSMIC cancer mutations	ovary-carcinoma-endometrioid_carcinoma	464	7	16828	49	ERBB4,DCLK2,NTRK2,RPS6KA2,CAMK2G,PRKCA,NTRK3
3.700e-04	-7.90	Transmission across Chemical Synapses	REACTOME pathways	R-HSA-112315	217	5	10285	30	SLC1A2,CAMK2G,ADCY2,PRKCA,RPS6KA2
3.766e-04	-7.88	soft_tissue	COSMIC cancer mutations	soft_tissue	5828	29	16828	49	LSAMP,ERBB4,NPAS3,ADCY2,LRP1B,CDH20,GPC5,TNC,CTNND2,NTRK2,CAMK2G,SOX5,NKAIN3,NRG3,GLIS3,TRPM3,NEBL,FMN2,RYR3,NTRK3,PARD3,SORBS1,SLC1A2,SYNE1,HPSE2,NAV2,GPM6A,MACF1,RORA
3.847e-04	-7.86	actin cytoskeleton	cellular component	GO:0015629	520	7	19108	50	MACF1,KALRN,FMN2,ABLIM1,CTNNA2,NEBL,SORBS1
3.868e-04	-7.86	Tyr_kinase_rcpt_2_CS	interpro domains	IPR002011	11	2	18521	50	NTRK3,NTRK2
4.170e-04	-7.78	Calcium signaling pathway	KEGG pathways	hsa04020	181	5	7161	26	ADCY2,ERBB4,RYR3,CAMK2G,PRKCA
4.170e-04	-7.78	Calcium signaling pathway	KEGG pathways	ko04020	181	5	7161	26	ERBB4,ADCY2,CAMK2G,PRKCA,RYR3
4.216e-04	-7.77	ATP binding	molecular function	GO:0005524	1467	12	18094	49	ADCY2,ERBB4,PRKCA,KALRN,DCLK2,DGKG,RPS6KA2,NTRK2,NTRK3,CAMK2G,ATP1A2,NAV2
4.244e-04	-7.76	Signaling by ERBB2	REACTOME pathways	R-HSA-1227986	51	3	10285	30	NRG3,ERBB4,PRKCA
4.352e-04	-7.74	Neuronal System	REACTOME pathways	R-HSA-112316	349	6	10285	30	CAMK2G,SLC1A2,NRXN1,ADCY2,PRKCA,RPS6KA2
4.698e-04	-7.66	amino acid transport	biological process	GO:0006865	132	4	18204	50	GFAP,SFXN5,SLC1A2,NTRK2
4.781e-04	-7.65	stomach-adenocarcinoma	COSMIC cancer mutations	stomach-adenocarcinoma	4101	23	16828	49	TNC,PARD3,ATP1A2,CTNND2,SYNE1,PSD2,SLC1A2,MGAT4C,ABLIM1,KALRN,RORA,NAV2,MACF1,SLC4A4,NRG3,ERBB4,NEBL,RFX4,GPC5,LRP1B,CDH20,PRKCA,FMN2
5.164e-04	-7.57	testis-germ_cell_tumour-seminoma	COSMIC cancer mutations	testis-germ_cell_tumour-seminoma	648	8	16828	49	SYNE1,ERBB4,NTRK3,PRKCA,DCLK2,CAMK2G,NTRK2,RPS6KA2
5.231e-04	-7.56	large_intestine-caecum-adenoma	COSMIC cancer mutations	large_intestine-caecum-adenoma	229	5	16828	49	KALRN,CTNND2,ERBB4,HPSE2,LRP1B
5.245e-04	-7.55	signaling	biological process	GO:0023052	4968	25	18204	50	RPS6KA2,PRKCA,DCLK2,ATP1A2,FMN2,NRG3,NRXN1,RORA,CTNND2,ADCY2,PITPNC1,NTRK3,DTNA,PARD3,MACF1,RYR3,SORBS1,NDRG2,KALRN,TNC,SLC1A2,NTRK2,DGKG,CAMK2G,ERBB4
5.403e-04	-7.52	Transmembrane transport of small molecules	REACTOME pathways	R-HSA-382551	677	8	10285	30	CAMK2G,SLC1A2,ADCY2,TRPM3,ATP1A2,SLC4A4,SLC14A1,RYR3
5.522e-04	-7.50	neuron projection development	biological process	GO:0031175	693	8	18204	50	GPM6A,PARD3,NRXN1,KALRN,GFAP,TNC,CTNNA2,CTNND2
5.545e-04	-7.50	breast-carcinoma-ductolobular_carcinoma	COSMIC cancer mutations	breast-carcinoma-ductolobular_carcinoma	1619	13	16828	49	CDH20,DTNA,NDRG2,FMN2,DGKG,NTRK3,ABLIM1,MACF1,KALRN,RORA,SORBS1,SYNE1,CTNND2
5.545e-04	-7.50	ductolobular_carcinoma	COSMIC cancer mutations	ductolobular_carcinoma	1619	13	16828	49	NDRG2,CDH20,DTNA,NTRK3,DGKG,FMN2,SYNE1,CTNND2,SORBS1,ABLIM1,RORA,KALRN,MACF1
5.566e-04	-7.49	ovary-carcinoma-serous_carcinoma	COSMIC cancer mutations	ovary-carcinoma-serous_carcinoma	10710	42	16828	49	HPSE2,MGAT4C,KALRN,RORA,NAV2,DCLK2,MACF1,PARD3,MSI2,SYNE1,SORBS1,SLC1A2,NEBL,DTNA,RYR3,NTRK3,NTM,PRKCA,FMN2,DGKG,RPS6KA2,GLIS3,GFAP,SFXN5,TRPM3,NRG3,SOX5,NTRK2,CAMK2G,TNC,ATP1A2,CTNND2,PSD2,ADCY2,GPC5,CDH20,LRP1B,LSAMP,SLC4A4,NPAS3,NRXN1,ERBB4
5.593e-04	-7.49	Ion homeostasis	REACTOME pathways	R-HSA-5578775	56	3	10285	30	CAMK2G,ATP1A2,RYR3
5.739e-04	-7.46	cell body	cellular component	GO:0044297	556	7	19108	50	PSD2,GPM6A,ATP1A2,SLC1A2,CTNND2,NRXN1,GFAP
5.776e-04	-7.46	CHAT (choline O-acetyltransferase)	protein interactions	1103	14	2	19454	50	CAMK2G,PRKCA
5.849e-04	-7.44	lung-carcinoid-endocrine_tumour	COSMIC cancer mutations	lung-carcinoid-endocrine_tumour	502	7	16828	49	ERBB4,RPS6KA2,CAMK2G,NTRK2,DCLK2,PRKCA,NTRK3
5.959e-04	-7.43	RECEPTOR_TYR_KIN_II	prosite domains	PS00239	11	2	12186	41	NTRK2,NTRK3
6.017e-04	-7.42	cell communication	biological process	GO:0007154	5010	25	18204	50	MACF1,RYR3,SORBS1,NDRG2,KALRN,TNC,NTRK2,SLC1A2,DGKG,CAMK2G,ERBB4,RPS6KA2,PRKCA,DCLK2,ATP1A2,FMN2,NRG3,NRXN1,RORA,CTNND2,ADCY2,PITPNC1,NTRK3,PARD3,DTNA
6.096e-04	-7.40	adenyl ribonucleotide binding	molecular function	GO:0032559	1528	12	18094	49	KALRN,PRKCA,ERBB4,ADCY2,NAV2,ATP1A2,CAMK2G,NTRK2,NTRK3,RPS6KA2,DGKG,DCLK2
6.144e-04	-7.39	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm	7307	33	16828	49	NKAIN3,GLIS3,SFXN5,NRG3,NEBL,RFX4,RYR3,NTRK3,PRKCA,DGKG,FMN2,PARD3,SYNE1,SLC1A2,HPSE2,MGAT4C,ABLIM1,RORA,KALRN,GPM6A,NAV2,MACF1,LSAMP,ERBB4,ADCY2,GPC5,LRP1B,CDH20,TNC,CTNND2,PSD2,SOX5,NTRK2
6.239e-04	-7.38	nasopharyngeal_carcinoma	COSMIC cancer mutations	nasopharyngeal_carcinoma	1425	12	16828	49	RFX4,PRKCA,RPS6KA2,FMN2,SFXN5,SLC4A4,PITPNC1,NTRK2,ATP1A2,SYNE1,CTNND2,SLC1A2
6.239e-04	-7.38	upper_aerodigestive_tract-pharynx-carcinoma-nasopharyngeal_carcinoma	COSMIC cancer mutations	upper_aerodigestive_tract-pharynx-carcinoma-nasopharyngeal_carcinoma	1425	12	16828	49	CTNND2,SYNE1,SLC1A2,ATP1A2,NTRK2,PITPNC1,SLC4A4,SFXN5,PRKCA,FMN2,RPS6KA2,RFX4
6.257e-04	-7.38	transferase activity, transferring phosphorus-containing groups	molecular function	GO:0016772	903	9	18094	49	ERBB4,PRKCA,KALRN,NTRK3,NTRK2,RPS6KA2,CAMK2G,DCLK2,DGKG
6.276e-04	-7.37	lung-carcinoid-endocrine_tumour-atypical	COSMIC cancer mutations	lung-carcinoid-endocrine_tumour-atypical	508	7	16828	49	ERBB4,CAMK2G,RPS6KA2,NTRK2,DCLK2,NTRK3,PRKCA
6.289e-04	-7.37	ERBB2 Activates PTK6 Signaling	REACTOME pathways	R-HSA-8847993	13	2	10285	30	ERBB4,NRG3
6.309e-04	-7.37	transmembrane receptor protein tyrosine kinase activity	molecular function	GO:0004714	62	3	18094	49	ERBB4,NTRK3,NTRK2
6.588e-04	-7.33	sodium ion export across plasma membrane	biological process	GO:0036376	14	2	18204	50	SLC4A4,ATP1A2
6.635e-04	-7.32	FLOT2 (flotillin 2)	protein interactions	2319	273	5	19454	50	RPS6KA2,SLC14A1,SOX5,PARD3,NTRK2
6.805e-04	-7.29	atypical	COSMIC cancer mutations	atypical	515	7	16828	49	ERBB4,NTRK3,PRKCA,NTRK2,CAMK2G,RPS6KA2,DCLK2
6.853e-04	-7.29	hairy_cell_leukaemia	COSMIC cancer mutations	hairy_cell_leukaemia	1440	12	16828	49	NRXN1,RFX4,LRP1B,CDH20,NEBL,RYR3,NTRK3,FMN2,SYNE1,CTNND2,MACF1,NAV2
6.853e-04	-7.29	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-hairy_cell_leukaemia	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-hairy_cell_leukaemia	1440	12	16828	49	CTNND2,SYNE1,NAV2,MACF1,NRXN1,NTRK3,RYR3,FMN2,NEBL,LRP1B,CDH20,RFX4
6.938e-04	-7.27	endometrium-carcinoma-serous_carcinoma	COSMIC cancer mutations	endometrium-carcinoma-serous_carcinoma	1442	12	16828	49	LSAMP,SLC4A4,NRXN1,TRPM3,GPC5,LRP1B,FMN2,RYR3,PARD3,SORBS1,CTNND2,SYNE1
7.080e-04	-7.25	astrocytoma_Grade_I	COSMIC cancer mutations	astrocytoma_Grade_I	139	4	16828	49	LRP1B,GPC5,PARD3,NRG3
7.324e-04	-7.22	SHC1 events in ERBB4 signaling	REACTOME pathways	R-HSA-1250347	14	2	10285	30	NRG3,ERBB4
7.385e-04	-7.21	DTNBP1 (dystrobrevin binding protein 1)	protein interactions	84062	159	4	19454	50	KALRN,MACF1,SYNE1,DTNA
7.640e-04	-7.18	central_nervous_system-brain-glioma-oligodendroglioma_Grade_III	COSMIC cancer mutations	central_nervous_system-brain-glioma-oligodendroglioma_Grade_III	249	5	16828	49	MGAT4C,GLIS3,SYNE1,NAV2,MACF1
7.849e-04	-7.15	germ_cell_tumour	COSMIC cancer mutations	germ_cell_tumour	867	9	16828	49	NTRK2,CAMK2G,MACF1,RPS6KA2,DCLK2,NTRK3,PRKCA,ERBB4,SYNE1
7.919e-04	-7.14	DSCAM (DS cell adhesion molecule)	protein interactions	1826	162	4	19454	50	SYNE1,GFAP,MACF1,KALRN
8.014e-04	-7.13	Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell	REACTOME pathways	R-HSA-112314	146	4	10285	30	PRKCA,ADCY2,CAMK2G,RPS6KA2
8.081e-04	-7.12	skin-subungual-malignant_melanoma-acral_lentiginous	COSMIC cancer mutations	skin-subungual-malignant_melanoma-acral_lentiginous	144	4	16828	49	MACF1,SYNE1,CDH20,LRP1B
8.168e-04	-7.11	Neurotrophin signaling pathway	KEGG pathways	hsa04722	119	4	7161	26	NTRK3,CAMK2G,NTRK2,RPS6KA2
8.168e-04	-7.11	Neurotrophin signaling pathway	KEGG pathways	ko04722	119	4	7161	26	NTRK3,CAMK2G,RPS6KA2,NTRK2
8.177e-04	-7.11	salivary_gland-carcinoma	COSMIC cancer mutations	salivary_gland-carcinoma	383	6	16828	49	NTRK3,PRKCA,RPS6KA2,ERBB4,NTRK2,CAMK2G
8.177e-04	-7.11	upper_aerodigestive_tract-mouth-carcinoma-adenoid_cystic_carcinoma	COSMIC cancer mutations	upper_aerodigestive_tract-mouth-carcinoma-adenoid_cystic_carcinoma	383	6	16828	49	NTRK3,PRKCA,RPS6KA2,ERBB4,CAMK2G,NTRK2
8.177e-04	-7.11	upper_aerodigestive_tract-carcinoma	COSMIC cancer mutations	upper_aerodigestive_tract-carcinoma	383	6	16828	49	NTRK3,PRKCA,CAMK2G,RPS6KA2,NTRK2,ERBB4
8.177e-04	-7.11	upper_aerodigestive_tract-lymph_node-carcinoma-adenoid_cystic_carcinoma	COSMIC cancer mutations	upper_aerodigestive_tract-lymph_node-carcinoma-adenoid_cystic_carcinoma	383	6	16828	49	ERBB4,NTRK2,RPS6KA2,CAMK2G,PRKCA,NTRK3
8.177e-04	-7.11	upper_aerodigestive_tract-head_neck-carcinoma-adenoid_cystic_carcinoma	COSMIC cancer mutations	upper_aerodigestive_tract-head_neck-carcinoma-adenoid_cystic_carcinoma	383	6	16828	49	ERBB4,CAMK2G,RPS6KA2,NTRK2,NTRK3,PRKCA
8.251e-04	-7.10	Axon guidance	REACTOME pathways	R-HSA-422475	549	7	10285	30	ERBB4,RPS6KA2,KALRN,NRG3,ABLIM1,PRKCA,CAMK2G
8.304e-04	-7.09	CH	pfam domains	PF00307	67	3	17795	49	SYNE1,NAV2,MACF1
8.309e-04	-7.09	PARD3 (par-3 family cell polarity regulator)	protein interactions	56288	287	5	19454	50	DTNA,SORBS1,NTRK2,PARD3,NTRK3
8.435e-04	-7.08	ERBB2 Regulates Cell Motility	REACTOME pathways	R-HSA-6785631	15	2	10285	30	ERBB4,NRG3
8.567e-04	-7.06	seminoma	COSMIC cancer mutations	seminoma	700	8	16828	49	CAMK2G,RPS6KA2,NTRK2,DCLK2,NTRK3,PRKCA,ERBB4,SYNE1
8.587e-04	-7.06	ErbB Signaling Pathway	WikiPathways	WP673	54	3	5310	19	ERBB4,PRKCA,NRG3
8.657e-04	-7.05	asymmetric cell division	biological process	GO:0008356	16	2	18204	50	SOX5,PARD3
8.727e-04	-7.04	subungual	COSMIC cancer mutations	subungual	147	4	16828	49	MACF1,SYNE1,LRP1B,CDH20
8.771e-04	-7.04	oesophagus-carcinoma	COSMIC cancer mutations	oesophagus-carcinoma	4269	23	16828	49	LRP1B,RFX4,CDH20,ADCY2,NTM,RYR3,NTRK3,RPS6KA2,FMN2,TRPM3,SLC4A4,NRG3,HPSE2,KALRN,SOX5,MACF1,NTRK2,GPM6A,PARD3,SYNE1,PSD2,CTNND2,SORBS1
8.793e-04	-7.04	YWHAG (tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein gamma)	protein interactions	7532	1211	10	19454	50	CAMK2G,MACF1,SORBS1,PARD3,ABLIM1,PITPNC1,PRKCA,FMN2,DCLK2,NAV2
9.010e-04	-7.01	upper_aerodigestive_tract-pharynx-carcinoma-squamous_cell_carcinoma	COSMIC cancer mutations	upper_aerodigestive_tract-pharynx-carcinoma-squamous_cell_carcinoma	1485	12	16828	49	SORBS1,SYNE1,SLC14A1,MACF1,NRG3,NPAS3,DGKG,FMN2,RYR3,GPC5,DTNA,LRP1B
9.072e-04	-7.01	prostate	COSMIC cancer mutations	prostate	13883	48	16828	49	HPSE2,ABLIM1,RORA,NAV2,GPM6A,MACF1,SORBS1,SLC1A2,NEBL,RFX4,NTRK3,GFAP,TRPM3,SOX5,NTRK2,TNC,CTNND2,CDH20,LSAMP,NPAS3,PITPNC1,MGAT4C,KALRN,DCLK2,SLC14A1,PARD3,MSI2,SYNE1,DTNA,RYR3,NTM,PRKCA,FMN2,DGKG,RPS6KA2,NKAIN3,GLIS3,SFXN5,NRG3,ATP1A2,PSD2,NDRG2,ADCY2,GPC5,LRP1B,SLC4A4,NRXN1,ERBB4
9.623e-04	-6.95	GRB2 events in ERBB2 signaling	REACTOME pathways	R-HSA-1963640	16	2	10285	30	ERBB4,NRG3
9.623e-04	-6.95	PI3K events in ERBB2 signaling	REACTOME pathways	R-HSA-1963642	16	2	10285	30	ERBB4,NRG3
9.689e-04	-6.94	presynaptic membrane	cellular component	GO:0042734	168	4	19108	50	ERBB4,GPM6A,SLC1A2,NRXN1
9.965e-04	-6.91	plasma membrane bounded cell projection organization	biological process	GO:0120036	1152	10	18204	50	TNC,NRXN1,GFAP,KALRN,PARD3,GPM6A,ABLIM1,CTNND2,RFX4,CTNNA2
1.008e-03	-6.90	CDC37 (cell division cycle 37, HSP90 cochaperone)	protein interactions	11140	623	7	19454	50	RPS6KA2,PRKCA,GFAP,CAMK2G,NTRK3,NTRK2,DCLK2
1.022e-03	-6.89	ADGRL2 (adhesion G protein-coupled receptor L2)	protein interactions	23266	77	3	19454	50	NTRK2,PARD3,RPS6KA2
1.025e-03	-6.88	adenyl nucleotide binding	molecular function	GO:0030554	1620	12	18094	49	ATP1A2,NAV2,DGKG,DCLK2,CAMK2G,RPS6KA2,NTRK3,NTRK2,PRKCA,KALRN,ERBB4,ADCY2
1.049e-03	-6.86	animal organ development	biological process	GO:0048513	2846	17	18204	50	SLC1A2,NTRK2,SYNE1,CTNNA2,SOX5,ERBB4,NTRK3,GPM6A,NEBL,ABLIM1,NDRG2,RFX4,RORA,TNC,DCLK2,ATP1A2,NRG3
1.055e-03	-6.85	SLC4A7 (solute carrier family 4 member 7)	protein interactions	9497	175	4	19454	50	NTRK3,SLC4A4,NTRK2,RPS6KA2
1.057e-03	-6.85	dendritic spine	cellular component	GO:0043197	172	4	19108	50	SYNE1,GPM6A,ATP1A2,NTRK2
1.077e-03	-6.83	RRAD (RRAD, Ras related glycolysis inhibitor and calcium channel regulator)	protein interactions	6236	19	2	19454	50	PRKCA,CAMK2G
1.080e-03	-6.83	cell surface receptor protein tyrosine kinase signaling pathway	biological process	GO:0007169	428	6	18204	50	NTRK3,NRG3,SORBS1,KALRN,NTRK2,ERBB4
1.088e-03	-6.82	dendrite	cellular component	GO:0030425	620	7	19108	50	PSD2,ADCY2,NTRK2,GPM6A,SYNE1,ATP1A2,CTNND2
1.104e-03	-6.81	neuron spine	cellular component	GO:0044309	174	4	19108	50	ATP1A2,GPM6A,SYNE1,NTRK2
1.108e-03	-6.80	dendritic tree	cellular component	GO:0097447	622	7	19108	50	CTNND2,NTRK2,ADCY2,ATP1A2,GPM6A,SYNE1,PSD2
1.115e-03	-6.80	astrocyte projection	cellular component	GO:0097449	19	2	19108	50	SLC1A2,GFAP
1.124e-03	-6.79	ERBB4 (erb-b2 receptor tyrosine kinase 4)	protein interactions	2066	178	4	19454	50	NTRK2,KALRN,ERBB4,NRG3
1.127e-03	-6.79	extrinsic component of membrane	cellular component	GO:0019898	175	4	19108	50	KALRN,CDH20,CTNNA2,DTNA
1.155e-03	-6.76	AFDN (afadin, adherens junction formation factor)	protein interactions	4301	309	5	19454	50	MACF1,SORBS1,DTNA,PARD3,NRXN1
1.172e-03	-6.75	C11orf52 (chromosome 11 open reading frame 52)	protein interactions	91894	310	5	19454	50	FMN2,PARD3,ABLIM1,DTNA,MACF1
1.181e-03	-6.74	metal ion transmembrane transporter activity	molecular function	GO:0046873	442	6	18094	49	TRPM3,GPM6A,SLC4A4,RYR3,ATP1A2,SLC1A2
1.194e-03	-6.73	PDZD2 (PDZ domain containing 2)	protein interactions	23037	20	2	19454	50	CTNND2,NRXN1
1.194e-03	-6.73	DOK5 (docking protein 5)	protein interactions	55816	20	2	19454	50	NTRK2,NTRK3
1.209e-03	-6.72	serous_carcinoma	COSMIC cancer mutations	serous_carcinoma	10987	42	16828	49	HPSE2,MGAT4C,KALRN,RORA,DCLK2,MACF1,NAV2,PARD3,MSI2,SYNE1,SLC1A2,SORBS1,DTNA,NEBL,NTM,PRKCA,NTRK3,RYR3,RPS6KA2,DGKG,FMN2,TRPM3,SFXN5,GLIS3,GFAP,NRG3,SOX5,CAMK2G,NTRK2,ATP1A2,TNC,PSD2,CTNND2,GPC5,LRP1B,CDH20,ADCY2,LSAMP,NRXN1,SLC4A4,NPAS3,ERBB4
1.222e-03	-6.71	KIF20A (kinesin family member 20A)	protein interactions	10112	1044	9	19454	50	MACF1,PARD3,GFAP,NEBL,ABLIM1,SYNE1,RORA,NAV2,MSI2
1.227e-03	-6.70	regulation of neurotransmitter uptake	biological process	GO:0051580	19	2	18204	50	ATP1A2,GFAP
1.250e-03	-6.68	central_nervous_system-brain-glioma-oligodendroglioma_Grade_II	COSMIC cancer mutations	central_nervous_system-brain-glioma-oligodendroglioma_Grade_II	73	3	16828	49	NAV2,MACF1,SYNE1
1.261e-03	-6.68	regulation of ERK1 and ERK2 cascade	biological process	GO:0070372	295	5	18204	50	NTRK3,PRKCA,ERBB4,NDRG2,NTRK2
1.283e-03	-6.66	dicarboxylic acid transport	biological process	GO:0006835	78	3	18204	50	SLC1A2,NTRK2,GFAP
1.300e-03	-6.65	bone-femur-chondrosarcoma	COSMIC cancer mutations	bone-femur-chondrosarcoma	419	6	16828	49	LRP1B,ADCY2,HPSE2,NAV2,PSD2,SLC4A4
1.301e-03	-6.64	oligodendroglioma_Grade_II	COSMIC cancer mutations	oligodendroglioma_Grade_II	74	3	16828	49	SYNE1,NAV2,MACF1
1.314e-03	-6.63	haematopoietic_and_lymphoid_tissue-lymph_node-lymphoid_neoplasm-diffuse_large_B_cell_lymphoma	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue-lymph_node-lymphoid_neoplasm-diffuse_large_B_cell_lymphoma	748	8	16828	49	NEBL,LRP1B,DTNA,NTRK2,SOX5,PARD3,CTNND2,SYNE1
1.314e-03	-6.63	Tyr_kinase_cat_dom	interpro domains	IPR020635	80	3	18521	50	NTRK3,NTRK2,ERBB4
1.318e-03	-6.63	SHC4 (SHC adaptor protein 4)	protein interactions	399694	21	2	19454	50	ERBB4,NTRK2
1.318e-03	-6.63	TENM1 (teneurin transmembrane protein 1)	protein interactions	10178	21	2	19454	50	MACF1,SORBS1
1.359e-03	-6.60	cell projection organization	biological process	GO:0030030	1200	10	18204	50	CTNNA2,RFX4,CTNND2,ABLIM1,GPM6A,PARD3,KALRN,GFAP,NRXN1,TNC
1.361e-03	-6.60	aspartate transmembrane transport	biological process	GO:0015810	20	2	18204	50	GFAP,SLC1A2
1.362e-03	-6.60	CH_dom	interpro domains	IPR001715	81	3	18521	50	SYNE1,MACF1,NAV2
1.373e-03	-6.59	transmembrane receptor protein kinase activity	molecular function	GO:0019199	81	3	18094	49	ERBB4,NTRK3,NTRK2
1.379e-03	-6.59	adrenal_cortical_carcinoma	COSMIC cancer mutations	adrenal_cortical_carcinoma	2256	15	16828	49	TRPM3,NRG3,LRP1B,RFX4,NTRK3,FMN2,DGKG,ATP1A2,TNC,SYNE1,CTNND2,SLC1A2,HPSE2,SOX5,NTRK2
1.407e-03	-6.57	FAM171A1 (family with sequence similarity 171 member A1)	protein interactions	221061	86	3	19454	50	NTRK2,PARD3,NTRK3
1.411e-03	-6.56	CH_dom_sf	interpro domains	IPR036872	82	3	18521	50	SYNE1,MACF1,NAV2
1.414e-03	-6.56	Ser/Thr_kinase_AS	interpro domains	IPR008271	308	5	18521	50	CAMK2G,KALRN,DCLK2,PRKCA,RPS6KA2
1.427e-03	-6.55	somatodendritic compartment	cellular component	GO:0036477	842	8	19108	50	PSD2,ADCY2,NTRK2,GPM6A,SYNE1,ATP1A2,CTNND2,NRXN1
1.455e-03	-6.53	PLCG2 (phospholipase C gamma 2)	protein interactions	5336	87	3	19454	50	ERBB4,PRKCA,NTRK3
1.481e-03	-6.52	stress fiber	cellular component	GO:0001725	86	3	19108	50	ABLIM1,NEBL,SORBS1
1.481e-03	-6.52	contractile actin filament bundle	cellular component	GO:0097517	86	3	19108	50	SORBS1,NEBL,ABLIM1
1.506e-03	-6.50	thyroid-carcinoma-medullary_carcinoma	COSMIC cancer mutations	thyroid-carcinoma-medullary_carcinoma	290	5	16828	49	SLC1A2,NRG3,GFAP,NTRK3,KALRN
1.506e-03	-6.50	medullary_carcinoma	COSMIC cancer mutations	medullary_carcinoma	290	5	16828	49	SLC1A2,NRG3,KALRN,GFAP,NTRK3
1.513e-03	-6.49	Syndecan interactions	REACTOME pathways	R-HSA-3000170	20	2	10285	30	TNC,PRKCA
1.530e-03	-6.48	urinary_tract-bladder-carcinoma	COSMIC cancer mutations	urinary_tract-bladder-carcinoma	14050	48	16828	49	TNC,CTNND2,NTRK2,SOX5,LSAMP,NPAS3,CDH20,SORBS1,SLC1A2,ABLIM1,HPSE2,GPM6A,NAV2,MACF1,RORA,GFAP,TRPM3,NEBL,RFX4,NTRK3,ATP1A2,PSD2,CAMK2G,ERBB4,SLC4A4,NRXN1,ADCY2,LRP1B,GPC5,NDRG2,MSI2,PARD3,SLC14A1,SYNE1,MGAT4C,PITPNC1,DCLK2,KALRN,NRG3,GLIS3,SFXN5,DTNA,FMN2,DGKG,RPS6KA2,RYR3,PRKCA,NTM
1.537e-03	-6.48	cellular component organization	biological process	GO:0016043	5636	26	18204	50	CDH20,PITPNC1,CTNNA2,CTNND2,TRPM3,GPM6A,PARD3,NEBL,PRKCA,ABLIM1,RFX4,NRXN1,DCLK2,FMN2,NRG3,SLC1A2,HPSE2,SYNE1,NAV2,GFAP,ERBB4,SORBS1,MACF1,RYR3,KALRN,TNC
1.548e-03	-6.47	SFN (stratifin)	protein interactions	2810	671	7	19454	50	NAV2,PARD3,FMN2,NTRK3,SORBS1,MACF1,ABLIM1
1.578e-03	-6.45	YWHAH (tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein eta)	protein interactions	7533	1083	9	19454	50	PARD3,SORBS1,MACF1,CAMK2G,NAV2,DCLK2,FMN2,PITPNC1,ABLIM1
1.582e-03	-6.45	TIMM10B (translocase of inner mitochondrial membrane 10B)	protein interactions	26515	23	2	19454	50	MSI2,HPSE2
1.621e-03	-6.42	phosphate-containing compound metabolic process	biological process	GO:0006796	1681	12	18204	50	DCLK2,NTRK3,ATP1A2,CAMK2G,ERBB4,KALRN,RORA,DGKG,RPS6KA2,NTRK2,PRKCA,ADCY2
1.632e-03	-6.42	cellular response to organic cyclic compound	biological process	GO:0071407	464	6	18204	50	TNC,RORA,ATP1A2,SLC1A2,ADCY2,RYR3
1.648e-03	-6.41	stomach-carcinoma	COSMIC cancer mutations	stomach-carcinoma	439	6	16828	49	NTRK3,PRKCA,NTRK2,RPS6KA2,CAMK2G,ERBB4
1.655e-03	-6.40	TRIO (trio Rho guanine nucleotide exchange factor)	protein interactions	7204	91	3	19454	50	NAV2,PARD3,NTRK3
1.662e-03	-6.40	Adrenergic signaling in cardiomyocytes	KEGG pathways	hsa04261	144	4	7161	26	CAMK2G,PRKCA,ADCY2,ATP1A2
1.662e-03	-6.40	Adrenergic signaling in cardiomyocytes	KEGG pathways	ko04261	144	4	7161	26	CAMK2G,PRKCA,ADCY2,ATP1A2
1.669e-03	-6.40	HS-GAG degradation	REACTOME pathways	R-HSA-2024096	21	2	10285	30	HPSE2,GPC5
1.698e-03	-6.38	adrenal_gland-adrenal_gland-adrenal_cortical_carcinoma-virilizing_syndrome_producing	COSMIC cancer mutations	adrenal_gland-adrenal_gland-adrenal_cortical_carcinoma-virilizing_syndrome_producing	298	5	16828	49	CTNND2,FMN2,TNC,ATP1A2,LRP1B
1.700e-03	-6.38	transport across blood-brain barrier	biological process	GO:0150104	86	3	18204	50	SLC4A4,SLC1A2,ATP1A2
1.700e-03	-6.38	vascular transport	biological process	GO:0010232	86	3	18204	50	ATP1A2,SLC1A2,SLC4A4
1.715e-03	-6.37	human chr17q24.2	chromosome location	human chr17q24.2	32	2	26134	50	PRKCA,PITPNC1
1.723e-03	-6.36	RASGRF1 (Ras protein specific guanine nucleotide releasing factor 1)	protein interactions	5923	24	2	19454	50	NTRK3,NTRK2
1.743e-03	-6.35	Actinin_actin-bd_CS	interpro domains	IPR001589	23	2	18521	50	MACF1,SYNE1
1.745e-03	-6.35	Long-term potentiation	KEGG pathways	hsa04720	67	3	7161	26	RPS6KA2,PRKCA,CAMK2G
1.745e-03	-6.35	Long-term potentiation	KEGG pathways	ko04720	67	3	7161	26	RPS6KA2,CAMK2G,PRKCA
1.745e-03	-6.35	Calcium Regulation in the Cardiac Cell	WikiPathways	WP536	151	4	5310	19	RYR3,CAMK2G,PRKCA,ADCY2
1.797e-03	-6.32	actomyosin	cellular component	GO:0042641	92	3	19108	50	SORBS1,ABLIM1,NEBL
1.817e-03	-6.31	GRIN1 (glutamate ionotropic receptor NMDA type subunit 1)	protein interactions	2902	94	3	19454	50	NTRK2,CAMK2G,PRKCA
1.821e-03	-6.31	CH	smart domains	SM00033	66	3	9717	36	SYNE1,MACF1,NAV2
1.826e-03	-6.31	oligodendroglioma_Grade_III	COSMIC cancer mutations	oligodendroglioma_Grade_III	303	5	16828	49	MGAT4C,SYNE1,GLIS3,MACF1,NAV2
1.829e-03	-6.30	bone-Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour	COSMIC cancer mutations	bone-Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour	6023	28	16828	49	PARD3,SYNE1,ABLIM1,NAV2,DCLK2,MACF1,KALRN,RORA,NKAIN3,NRG3,GLIS3,TRPM3,NEBL,DTNA,DGKG,RYR3,NTRK3,TNC,ATP1A2,CTNND2,CAMK2G,NTRK2,SOX5,ERBB4,NPAS3,SLC4A4,ADCY2,LRP1B
1.848e-03	-6.29	chondrosarcoma	COSMIC cancer mutations	chondrosarcoma	1181	10	16828	49	NDRG2,HPSE2,LRP1B,ADCY2,KALRN,NAV2,LSAMP,PSD2,SLC4A4,ERBB4
1.848e-03	-6.29	phosphorus metabolic process	biological process	GO:0006793	1707	12	18204	50	DGKG,CAMK2G,ERBB4,NTRK3,ADCY2,NTRK2,KALRN,RORA,DCLK2,ATP1A2,PRKCA,RPS6KA2
1.854e-03	-6.29	bladder	COSMIC cancer mutations	bladder	14112	48	16828	49	PSD2,ATP1A2,CAMK2G,ERBB4,SLC4A4,NRXN1,ADCY2,LRP1B,GPC5,NDRG2,SYNE1,MSI2,PARD3,SLC14A1,DCLK2,KALRN,MGAT4C,PITPNC1,NRG3,GLIS3,SFXN5,FMN2,DGKG,RPS6KA2,RYR3,NTM,PRKCA,DTNA,CTNND2,TNC,NTRK2,SOX5,NPAS3,LSAMP,CDH20,SORBS1,SLC1A2,NAV2,GPM6A,MACF1,RORA,ABLIM1,HPSE2,GFAP,TRPM3,NTRK3,NEBL,RFX4
1.854e-03	-6.29	urinary_tract	COSMIC cancer mutations	urinary_tract	14112	48	16828	49	TRPM3,GFAP,RFX4,NEBL,NTRK3,SLC1A2,SORBS1,ABLIM1,HPSE2,MACF1,GPM6A,NAV2,RORA,LSAMP,NPAS3,CDH20,TNC,CTNND2,NTRK2,SOX5,NRG3,SFXN5,GLIS3,DTNA,RPS6KA2,DGKG,FMN2,PRKCA,NTM,RYR3,MSI2,PARD3,SLC14A1,SYNE1,MGAT4C,PITPNC1,DCLK2,KALRN,ERBB4,NRXN1,SLC4A4,LRP1B,GPC5,ADCY2,NDRG2,ATP1A2,PSD2,CAMK2G
1.870e-03	-6.28	DGKD (diacylglycerol kinase delta)	protein interactions	8527	25	2	19454	50	PRKCA,DGKG
1.884e-03	-6.27	Calponin-like domain	gene3d domains	1.10.418.10	79	3	14470	45	SYNE1,MACF1,NAV2
1.913e-03	-6.26	human chr4q31.23-q31.3	chromosome location	human chr4q31.23-q31.3	1	1	26134	50	DCLK2
1.913e-03	-6.26	human chr9q21.12-q21.13	chromosome location	human chr9q21.12-q21.13	1	1	26134	50	TRPM3
1.913e-03	-6.26	human chr10p11.22-p11.21	chromosome location	human chr10p11.22-p11.21	1	1	26134	50	PARD3
1.913e-03	-6.26	human chr2q22.1-q22.2	chromosome location	human chr2q22.1-q22.2	1	1	26134	50	LRP1B
1.913e-03	-6.26	human chr12q21.31-q21.32	chromosome location	human chr12q21.31-q21.32	1	1	26134	50	MGAT4C
1.913e-03	-6.26	human chr3q21.1-q21.2	chromosome location	human chr3q21.1-q21.2	1	1	26134	50	KALRN
1.913e-03	-6.26	human chr3q27.2-q27.3	chromosome location	human chr3q27.2-q27.3	1	1	26134	50	DGKG
1.913e-03	-6.26	human chr15q13.3-q14	chromosome location	human chr15q13.3-q14	1	1	26134	50	RYR3
1.957e-03	-6.24	bone-femur-other-chondroblastoma	COSMIC cancer mutations	bone-femur-other-chondroblastoma	183	4	16828	49	RYR3,NRG3,LRP1B,GPC5
1.972e-03	-6.23	cellular component assembly	biological process	GO:0022607	2472	15	18204	50	ERBB4,TRPM3,NEBL,PARD3,GPM6A,SLC1A2,CDH20,NRXN1,NRG3,FMN2,ABLIM1,SORBS1,PRKCA,RFX4,RYR3
1.984e-03	-6.22	breast-carcinoma-ductal_carcinoma	COSMIC cancer mutations	breast-carcinoma-ductal_carcinoma	14824	49	16828	49	LRP1B,GPC5,ADCY2,NDRG2,ERBB4,NRXN1,SLC4A4,CAMK2G,PSD2,ATP1A2,RPS6KA2,DGKG,FMN2,NTM,PRKCA,RYR3,DTNA,NRG3,SFXN5,GLIS3,NKAIN3,DCLK2,KALRN,MGAT4C,PITPNC1,SYNE1,MSI2,SLC14A1,PARD3,CDH20,NPAS3,LSAMP,NTRK2,SOX5,CTNND2,TNC,NTRK3,RFX4,NEBL,TRPM3,GFAP,MACF1,GPM6A,NAV2,RORA,ABLIM1,HPSE2,SLC1A2,SORBS1
1.987e-03	-6.22	carbohydrate derivative binding	molecular function	GO:0097367	2251	14	18094	49	HPSE2,DCLK2,DGKG,NTRK2,RPS6KA2,NTRK3,CAMK2G,ATP1A2,NAV2,ADCY2,TNC,ERBB4,KALRN,PRKCA
1.998e-03	-6.22	SHC1 (SHC adaptor protein 1)	protein interactions	6464	350	5	19454	50	NTRK3,NTRK2,GFAP,PRKCA,ERBB4
2.023e-03	-6.20	NTF3 (neurotrophin 3)	protein interactions	4908	26	2	19454	50	NTRK2,NTRK3
2.027e-03	-6.20	Oxytocin signaling pathway	KEGG pathways	hsa04921	152	4	7161	26	ADCY2,RYR3,PRKCA,CAMK2G
2.027e-03	-6.20	Oxytocin signaling pathway	KEGG pathways	ko04921	152	4	7161	26	PRKCA,CAMK2G,RYR3,ADCY2
2.030e-03	-6.20	actin filament bundle	cellular component	GO:0032432	96	3	19108	50	SORBS1,NEBL,ABLIM1
2.042e-03	-6.19	femur	COSMIC cancer mutations	femur	1197	10	16828	49	LRP1B,GPC5,ADCY2,HPSE2,FMN2,NAV2,RYR3,NRG3,PSD2,SLC4A4
2.062e-03	-6.18	neuron projection morphogenesis	biological process	GO:0048812	486	6	18204	50	PARD3,GPM6A,KALRN,NRXN1,CTNNA2,CTNND2
2.062e-03	-6.18	Bile secretion	KEGG pathways	hsa04976	71	3	7161	26	ADCY2,ATP1A2,SLC4A4
2.062e-03	-6.18	Bile secretion	KEGG pathways	ko04976	71	3	7161	26	ADCY2,ATP1A2,SLC4A4
2.063e-03	-6.18	Myometrial Relaxation and Contraction Pathways	WikiPathways	WP289	158	4	5310	19	CAMK2G,RYR3,ADCY2,PRKCA
2.065e-03	-6.18	prostate-adenoma	COSMIC cancer mutations	prostate-adenoma	1634	12	16828	49	NPAS3,TRPM3,ERBB4,PRKCA,NEBL,GPC5,LRP1B,SYNE1,PARD3,SOX5,DCLK2,MACF1
2.123e-03	-6.16	cell-cell junction	cellular component	GO:0005911	513	6	19108	50	PARD3,CDH20,ATP1A2,CTNNA2,SORBS1,CTNND2
2.147e-03	-6.14	Adherens junction	KEGG pathways	ko04520	72	3	7161	26	PARD3,SORBS1,CTNNA2
2.147e-03	-6.14	Adherens junction	KEGG pathways	hsa04520	72	3	7161	26	SORBS1,CTNNA2,PARD3
2.149e-03	-6.14	central_nervous_system-brain-glioma-astrocytoma_Grade_III	COSMIC cancer mutations	central_nervous_system-brain-glioma-astrocytoma_Grade_III	1419	11	16828	49	PRKCA,RYR3,NAV2,HPSE2,LRP1B,GPC5,ADCY2,TRPM3,ERBB4,NRG3,PARD3
2.152e-03	-6.14	Tyr_kinase_AS	interpro domains	IPR008266	95	3	18521	50	NTRK3,NTRK2,ERBB4
2.154e-03	-6.14	positive regulation of ERK1 and ERK2 cascade	biological process	GO:0070374	199	4	18204	50	NTRK3,PRKCA,ERBB4,NTRK2
2.171e-03	-6.13	plasma membrane bounded cell projection morphogenesis	biological process	GO:0120039	491	6	18204	50	KALRN,NRXN1,CTNND2,PARD3,CTNNA2,GPM6A
2.177e-03	-6.13	large_intestine-colon-carcinoma	COSMIC cancer mutations	large_intestine-colon-carcinoma	2612	16	16828	49	NRXN1,TRPM3,NRG3,NTRK3,FMN2,GPC5,LRP1B,ADCY2,SYNE1,PSD2,TNC,PARD3,RORA,KALRN,MACF1,NAV2
2.178e-03	-6.13	CXADR (CXADR Ig-like cell adhesion molecule)	protein interactions	1525	357	5	19454	50	PARD3,NEBL,RPS6KA2,SORBS1,MACF1
2.181e-03	-6.13	KCNJ12 (potassium inwardly rectifying channel subfamily J member 12)	protein interactions	3768	27	2	19454	50	ABLIM1,DTNA
2.185e-03	-6.13	LYN (LYN proto-oncogene, Src family tyrosine kinase)	protein interactions	4067	713	7	19454	50	ABLIM1,DTNA,ERBB4,MSI2,FMN2,MACF1,PARD3
2.200e-03	-6.12	EZR (ezrin)	protein interactions	7430	526	6	19454	50	DTNA,NEBL,ABLIM1,PRKCA,SORBS1,MACF1
2.230e-03	-6.11	PRKCG (protein kinase C gamma)	protein interactions	5582	101	3	19454	50	GFAP,PRKCA,PARD3
2.238e-03	-6.10	modulation of chemical synaptic transmission	biological process	GO:0050804	494	6	18204	50	NRXN1,GFAP,NTRK2,SYNE1,ATP1A2,NRG3
2.261e-03	-6.09	regulation of trans-synaptic signaling	biological process	GO:0099177	495	6	18204	50	NTRK2,SYNE1,GFAP,NRXN1,NRG3,ATP1A2
2.281e-03	-6.08	extrinsic component of plasma membrane	cellular component	GO:0019897	100	3	19108	50	CDH20,CTNNA2,DTNA
2.284e-03	-6.08	cell projection morphogenesis	biological process	GO:0048858	496	6	18204	50	KALRN,NRXN1,PARD3,GPM6A,CTNNA2,CTNND2
2.285e-03	-6.08	skin-upper_back-malignant_melanoma	COSMIC cancer mutations	skin-upper_back-malignant_melanoma	319	5	16828	49	GPC5,SYNE1,KALRN,MACF1,ERBB4
2.302e-03	-6.07	Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour	COSMIC cancer mutations	Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour	7434	32	16828	49	ABLIM1,DCLK2,MACF1,NAV2,RORA,KALRN,PARD3,SORBS1,SYNE1,DTNA,NEBL,DGKG,FMN2,RYR3,NTRK3,NKAIN3,NRG3,TRPM3,GLIS3,NTRK2,CAMK2G,SOX5,ATP1A2,TNC,PSD2,CTNND2,LRP1B,ADCY2,ERBB4,NRXN1,SLC4A4,NPAS3
2.304e-03	-6.07	C4-dicarboxylate transport	biological process	GO:0015740	26	2	18204	50	GFAP,SLC1A2
2.322e-03	-6.07	adrenal_gland	COSMIC cancer mutations	adrenal_gland	2628	16	16828	49	NRG3,TRPM3,RFX4,LRP1B,ADCY2,DGKG,FMN2,NTRK3,ATP1A2,TNC,SLC1A2,SYNE1,CTNND2,HPSE2,NTRK2,SOX5
2.322e-03	-6.07	Thyroid hormone synthesis	KEGG pathways	hsa04918	74	3	7161	26	PRKCA,ATP1A2,ADCY2
2.322e-03	-6.07	Thyroid hormone synthesis	KEGG pathways	ko04918	74	3	7161	26	PRKCA,ATP1A2,ADCY2
2.348e-03	-6.05	virilizing_syndrome_producing	COSMIC cancer mutations	virilizing_syndrome_producing	321	5	16828	49	FMN2,CTNND2,LRP1B,ATP1A2,TNC
2.362e-03	-6.05	skin-head_neck-carcinoma-squamous_cell_carcinoma	COSMIC cancer mutations	skin-head_neck-carcinoma-squamous_cell_carcinoma	14191	48	16828	49	DCLK2,KALRN,MGAT4C,PITPNC1,SYNE1,PARD3,SLC14A1,DGKG,FMN2,RPS6KA2,RYR3,NTM,PRKCA,DTNA,NRG3,GLIS3,SFXN5,NKAIN3,CAMK2G,PSD2,ATP1A2,ADCY2,GPC5,LRP1B,NDRG2,ERBB4,SLC4A4,NRXN1,GPM6A,NAV2,MACF1,RORA,ABLIM1,HPSE2,SORBS1,SLC1A2,NTRK3,NEBL,RFX4,GFAP,TRPM3,NTRK2,SOX5,CTNND2,TNC,CDH20,NPAS3,LSAMP
2.412e-03	-6.03	haematopoietic_and_lymphoid_tissue-spleen-lymphoid_neoplasm-marginal_zone_lymphoma	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue-spleen-lymphoid_neoplasm-marginal_zone_lymphoma	323	5	16828	49	LRP1B,ADCY2,NTM,SYNE1,SORBS1
2.484e-03	-6.00	protein kinase C-activating G protein-coupled receptor signaling pathway	biological process	GO:0007205	27	2	18204	50	DGKG,PARD3
2.495e-03	-5.99	LRRNT	pfam domains	PF01462	27	2	17795	49	NTRK2,NTRK3
2.514e-03	-5.99	CH	prosite domains	PS50021	81	3	12186	41	SYNE1,NAV2,MACF1
2.559e-03	-5.97	USP6NL (USP6 N-terminal like)	protein interactions	9712	106	3	19454	50	PARD3,NTRK3,NTRK2
2.570e-03	-5.96	App (amyloid beta precursor protein)	protein interactions	100689222	1	1	19454	50	LRP1B
2.570e-03	-5.96	Sytl1 (synaptotagmin-like 1)	protein interactions	269589	1	1	19454	50	NRXN1
2.570e-03	-5.96	Isl1 (ISL1 transcription factor, LIM/homeodomain)	protein interactions	16392	1	1	19454	50	GLIS3
2.570e-03	-5.96	Itga7 (integrin subunit alpha 7)	protein interactions	81008	1	1	19454	50	TNC
2.570e-03	-5.96	Bdnf (brain derived neurotrophic factor)	protein interactions	12064	1	1	19454	50	NTRK2
2.570e-03	-5.96	TAS2R20 (taste 2 receptor member 20)	protein interactions	259295	1	1	19454	50	PRKCA
2.570e-03	-5.96	IML3 (Iml3p)	protein interactions	852404	1	1	19454	50	GFAP
2.570e-03	-5.96	Hipk3 (homeodomain interacting protein kinase 3)	protein interactions	15259	1	1	19454	50	GLIS3
2.570e-03	-5.96	Agtrap (angiotensin II, type I receptor-associated protein)	protein interactions	11610	1	1	19454	50	PITPNC1
2.570e-03	-5.96	fbxw7.L (F-box and WD repeat domain containing 7 L homeolog)	protein interactions	734230	1	1	19454	50	PRKCA
2.570e-03	-5.96	Dynlt1 (dynein light chain Tctex-type 1)	protein interactions	83462	1	1	19454	50	NTRK2
2.573e-03	-5.96	cell morphogenesis	biological process	GO:0000902	687	7	18204	50	GPM6A,PARD3,NRXN1,KALRN,CTNNA2,CTNND2,CDH20
2.577e-03	-5.96	upper_back	COSMIC cancer mutations	upper_back	328	5	16828	49	ERBB4,MACF1,KALRN,SYNE1,GPC5
2.584e-03	-5.96	purine ribonucleoside triphosphate binding	molecular function	GO:0035639	1804	12	18094	49	ERBB4,KALRN,PRKCA,ADCY2,NAV2,ATP1A2,RPS6KA2,NTRK2,NTRK3,CAMK2G,DCLK2,DGKG
2.585e-03	-5.96	Pkinase	pfam domains	PF00069	347	5	17795	49	PRKCA,KALRN,DCLK2,RPS6KA2,CAMK2G
2.603e-03	-5.95	MAPRE3 (microtubule associated protein RP/EB family member 3)	protein interactions	22924	224	4	19454	50	NAV2,MACF1,ABLIM1,GPM6A
2.628e-03	-5.94	EFR3A (EFR3 homolog A)	protein interactions	23167	107	3	19454	50	NTRK3,PARD3,RPS6KA2
2.672e-03	-5.92	ACTININ_1	prosite domains	PS00019	23	2	12186	41	SYNE1,MACF1
2.672e-03	-5.92	ACTININ_2	prosite domains	PS00020	23	2	12186	41	SYNE1,MACF1
2.681e-03	-5.92	marginal_zone_lymphoma	COSMIC cancer mutations	marginal_zone_lymphoma	331	5	16828	49	NTM,SYNE1,SORBS1,LRP1B,ADCY2
2.688e-03	-5.92	PIK3R2 (phosphoinositide-3-kinase regulatory subunit 2)	protein interactions	5296	226	4	19454	50	ERBB4,RPS6KA2,NTRK3,NTRK2
2.698e-03	-5.92	FKBP1A (FKBP prolyl isomerase 1A)	protein interactions	2280	108	3	19454	50	ERBB4,RYR3,MSI2
2.700e-03	-5.91	SORBS1_SH3_2	interpro domains	IPR035611	1	1	18521	50	SORBS1
2.700e-03	-5.91	Nebulette_SH3	interpro domains	IPR035631	1	1	18521	50	NEBL
2.700e-03	-5.91	RSK3_STKc	interpro domains	IPR042766	1	1	18521	50	RPS6KA2
2.700e-03	-5.91	SORBS1_SH3_1	interpro domains	IPR035610	1	1	18521	50	SORBS1
2.700e-03	-5.91	NTRK2	interpro domains	IPR020455	1	1	18521	50	NTRK2
2.700e-03	-5.91	C1_DGKgamma_rpt2	interpro domains	IPR047475	1	1	18521	50	DGKG
2.700e-03	-5.91	NTRK3	interpro domains	IPR020446	1	1	18521	50	NTRK3
2.700e-03	-5.91	cPKC_alpha	interpro domains	IPR034663	1	1	18521	50	PRKCA
2.700e-03	-5.91	SORBS1_SH3	interpro domains	IPR035606	1	1	18521	50	SORBS1
2.700e-03	-5.91	CH_SYNE1_rpt1	interpro domains	IPR047290	1	1	18521	50	SYNE1
2.700e-03	-5.91	CH_SYNE1_rpt2	interpro domains	IPR047291	1	1	18521	50	SYNE1
2.708e-03	-5.91	brain-derived neurotrophic factor receptor activity	molecular function	GO:0060175	1	1	18094	49	NTRK2
2.709e-03	-5.91	large_intestine-caecum-carcinoma-adenocarcinoma	COSMIC cancer mutations	large_intestine-caecum-carcinoma-adenocarcinoma	14236	48	16828	49	TNC,CTNND2,NTRK2,SOX5,LSAMP,NPAS3,CDH20,SORBS1,SLC1A2,ABLIM1,HPSE2,NAV2,GPM6A,MACF1,RORA,GFAP,TRPM3,NEBL,RFX4,NTRK3,ATP1A2,PSD2,CAMK2G,ERBB4,SLC4A4,NRXN1,ADCY2,GPC5,LRP1B,NDRG2,SLC14A1,PARD3,SYNE1,MGAT4C,PITPNC1,DCLK2,KALRN,NKAIN3,NRG3,GLIS3,SFXN5,DTNA,FMN2,DGKG,RPS6KA2,RYR3,NTM,PRKCA
2.747e-03	-5.90	homologous chromosome movement towards spindle pole in meiosis I anaphase	biological process	GO:0051758	1	1	18204	50	FMN2
2.747e-03	-5.90	regulation of nucleus organization	biological process	GO:1903353	1	1	18204	50	SYNE1
2.747e-03	-5.90	directional guidance of interneurons involved in migration from the subpallium to the cortex	biological process	GO:0021840	1	1	18204	50	NRG3
2.747e-03	-5.90	trans-synaptic signaling by neuropeptide, modulating synaptic transmission	biological process	GO:0099551	1	1	18204	50	NTRK2
2.747e-03	-5.90	positive regulation of angiotensin-activated signaling pathway	biological process	GO:0110063	1	1	18204	50	PRKCA
2.747e-03	-5.90	negative regulation of calcium:sodium antiporter activity	biological process	GO:1903280	1	1	18204	50	ATP1A2
2.747e-03	-5.90	olfactory cortex development	biological process	GO:0021989	1	1	18204	50	ATP1A2
2.747e-03	-5.90	trans-synaptic signaling by neuropeptide	biological process	GO:0099540	1	1	18204	50	NTRK2
2.747e-03	-5.90	chemorepulsion involved in interneuron migration from the subpallium to the cortex	biological process	GO:0021842	1	1	18204	50	NRG3
2.749e-03	-5.90	Muscle contraction	REACTOME pathways	R-HSA-397014	204	4	10285	30	ATP1A2,CAMK2G,RYR3,SORBS1
2.777e-03	-5.89	cellular component organization or biogenesis	biological process	GO:0071840	5850	26	18204	50	SLC1A2,HPSE2,SYNE1,NAV2,ERBB4,GFAP,SORBS1,MACF1,RYR3,TNC,KALRN,PITPNC1,CDH20,CTNND2,CTNNA2,TRPM3,NEBL,GPM6A,PARD3,ABLIM1,PRKCA,RFX4,NRXN1,NRG3,DCLK2,FMN2
2.809e-03	-5.87	caecum	COSMIC cancer mutations	caecum	14248	48	16828	49	LSAMP,NPAS3,CDH20,TNC,CTNND2,NTRK2,SOX5,TRPM3,GFAP,RFX4,NEBL,NTRK3,SLC1A2,SORBS1,ABLIM1,HPSE2,MACF1,NAV2,GPM6A,RORA,ERBB4,NRXN1,SLC4A4,GPC5,LRP1B,ADCY2,NDRG2,ATP1A2,PSD2,CAMK2G,NKAIN3,NRG3,SFXN5,GLIS3,DTNA,RPS6KA2,FMN2,DGKG,PRKCA,NTM,RYR3,SLC14A1,PARD3,SYNE1,MGAT4C,PITPNC1,DCLK2,KALRN
2.862e-03	-5.86	ACTB (actin beta)	protein interactions	60	958	8	19454	50	SFXN5,MACF1,SORBS1,FMN2,PRKCA,ABLIM1,NEBL,DTNA
2.863e-03	-5.86	neurotrophin signaling pathway	biological process	GO:0038179	29	2	18204	50	NTRK3,NTRK2
2.863e-03	-5.86	peripheral nervous system axon ensheathment	biological process	GO:0032292	29	2	18204	50	PARD3,NTRK2
2.863e-03	-5.86	myelination in peripheral nervous system	biological process	GO:0022011	29	2	18204	50	PARD3,NTRK2
2.870e-03	-5.85	SH2D1B (SH2 domain containing 1B)	protein interactions	117157	31	2	19454	50	ABLIM1,ERBB4
2.870e-03	-5.85	AVPR1B (arginine vasopressin receptor 1B)	protein interactions	553	31	2	19454	50	FMN2,PRKCA
2.870e-03	-5.85	SH2B1 (SH2B adaptor protein 1)	protein interactions	25970	31	2	19454	50	NTRK2,ERBB4
2.888e-03	-5.85	protein serine kinase activity	molecular function	GO:0106310	362	5	18094	49	DCLK2,PRKCA,KALRN,CAMK2G,RPS6KA2
2.909e-03	-5.84	lung-carcinoma-large_cell_carcinoma	COSMIC cancer mutations	lung-carcinoma-large_cell_carcinoma	849	8	16828	49	ERBB4,SYNE1,CAMK2G,DCLK2,RPS6KA2,NTRK2,PRKCA,NTRK3
2.909e-03	-5.84	large_cell_carcinoma	COSMIC cancer mutations	large_cell_carcinoma	849	8	16828	49	SYNE1,ERBB4,NTRK3,PRKCA,NTRK2,DCLK2,CAMK2G,RPS6KA2
2.933e-03	-5.83	central_nervous_system-brainstem-glioma	COSMIC cancer mutations	central_nervous_system-brainstem-glioma	338	5	16828	49	HPSE2,TNC,LRP1B,GPC5,ERBB4
2.934e-03	-5.83	inorganic molecular entity transmembrane transporter activity	molecular function	GO:0015318	714	7	18094	49	GPM6A,SLC14A1,TRPM3,SLC4A4,SLC1A2,ATP1A2,RYR3
2.966e-03	-5.82	CaM pathway	REACTOME pathways	R-HSA-111997	28	2	10285	30	ADCY2,PRKCA
2.966e-03	-5.82	Calmodulin induced events	REACTOME pathways	R-HSA-111933	28	2	10285	30	ADCY2,PRKCA
2.973e-03	-5.82	catenin complex	cellular component	GO:0016342	31	2	19108	50	CDH20,CTNNA2
2.991e-03	-5.81	EDA (ectodysplasin A)	protein interactions	1896	112	3	19454	50	RPS6KA2,GPM6A,ERBB4
2.993e-03	-5.81	YWHAB (tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein beta)	protein interactions	7529	965	8	19454	50	DCLK2,NAV2,PITPNC1,ABLIM1,PARD3,MACF1,CAMK2G,SORBS1
3.000e-03	-5.81	Ion channel transport	REACTOME pathways	R-HSA-983712	209	4	10285	30	RYR3,CAMK2G,ATP1A2,TRPM3
3.005e-03	-5.81	SH3_domain	interpro domains	IPR001452	222	4	18521	50	KALRN,MACF1,NEBL,SORBS1
3.057e-03	-5.79	GRIA4 (glutamate ionotropic receptor AMPA type subunit 4)	protein interactions	2893	32	2	19454	50	PRKCA,CAMK2G
3.060e-03	-5.79	Proximal tubule bicarbonate reclamation	KEGG pathways	ko04964	23	2	7161	26	ATP1A2,SLC4A4
3.060e-03	-5.79	Proximal tubule bicarbonate reclamation	KEGG pathways	hsa04964	23	2	7161	26	SLC4A4,ATP1A2
3.062e-03	-5.79	neuron projection regeneration	biological process	GO:0031102	30	2	18204	50	TNC,GFAP
3.062e-03	-5.79	neurotransmitter uptake	biological process	GO:0001504	30	2	18204	50	SLC1A2,ATP1A2
3.093e-03	-5.78	MARK3 (microtubule affinity regulating kinase 3)	protein interactions	4140	235	4	19454	50	DTNA,MACF1,NTRK2,PARD3
3.110e-03	-5.77	-	gene3d domains	6.10.250.880	1	1	14470	45	ERBB4
3.112e-03	-5.77	Aldosterone synthesis and secretion	KEGG pathways	hsa04925	82	3	7161	26	ADCY2,PRKCA,CAMK2G
3.112e-03	-5.77	Aldosterone synthesis and secretion	KEGG pathways	ko04925	82	3	7161	26	PRKCA,CAMK2G,ADCY2
3.155e-03	-5.76	TyrKc	smart domains	SM00219	80	3	9717	36	NTRK3,ERBB4,NTRK2
3.180e-03	-5.75	CREB phosphorylation through the activation of Ras	REACTOME pathways	R-HSA-442742	29	2	10285	30	RPS6KA2,CAMK2G
3.188e-03	-5.75	CAMK2A (calcium/calmodulin dependent protein kinase II alpha)	protein interactions	815	237	4	19454	50	GPM6A,CAMK2G,GFAP,SOX5
3.204e-03	-5.74	cervix-carcinoma-squamous_cell_carcinoma	COSMIC cancer mutations	cervix-carcinoma-squamous_cell_carcinoma	11789	43	16828	49	PSD2,ATP1A2,ADCY2,GPC5,LRP1B,SLC4A4,NRXN1,ERBB4,KALRN,DCLK2,PITPNC1,MGAT4C,SYNE1,PARD3,RYR3,PRKCA,NTM,DGKG,FMN2,RPS6KA2,DTNA,GLIS3,SFXN5,NRG3,SOX5,NTRK2,CTNND2,TNC,CDH20,NPAS3,LSAMP,RORA,NAV2,GPM6A,MACF1,HPSE2,ABLIM1,SORBS1,SLC1A2,NTRK3,NEBL,RFX4,TRPM3
3.212e-03	-5.74	Downstream signal transduction	REACTOME pathways	R-HSA-186763	352	5	10285	30	ERBB4,NRG3,ADCY2,PRKCA,CAMK2G
3.222e-03	-5.74	CDH2 (cadherin 2)	protein interactions	1000	115	3	19454	50	CTNND2,PARD3,NTRK3
3.237e-03	-5.73	cervix	COSMIC cancer mutations	cervix	11793	43	16828	49	PARD3,SORBS1,SLC1A2,SYNE1,MGAT4C,ABLIM1,HPSE2,PITPNC1,NAV2,GPM6A,MACF1,DCLK2,KALRN,RORA,NRG3,GLIS3,SFXN5,TRPM3,NEBL,DTNA,RFX4,DGKG,FMN2,RPS6KA2,RYR3,NTRK3,NTM,PRKCA,TNC,ATP1A2,CTNND2,PSD2,NTRK2,SOX5,LSAMP,ERBB4,NPAS3,SLC4A4,NRXN1,ADCY2,LRP1B,GPC5,CDH20
3.314e-03	-5.71	Axon guidance	KEGG pathways	hsa04360	174	4	7161	26	ABLIM1,PRKCA,CAMK2G,PARD3
3.314e-03	-5.71	Axon guidance	KEGG pathways	ko04360	174	4	7161	26	ABLIM1,PRKCA,CAMK2G,PARD3
3.372e-03	-5.69	DAP12 signaling	REACTOME pathways	R-HSA-2424491	356	5	10285	30	PRKCA,ADCY2,CAMK2G,ERBB4,NRG3
3.375e-03	-5.69	cell migration	biological process	GO:0016477	921	8	18204	50	CTNNA2,CDH20,NTRK2,FMN2,GPM6A,NRG3,ERBB4,GPC5
3.385e-03	-5.69	ERBIN (erbb2 interacting protein)	protein interactions	55914	241	4	19454	50	CTNND2,NTRK2,NTRK3,PARD3
3.401e-03	-5.68	Ca-dependent events	REACTOME pathways	R-HSA-111996	30	2	10285	30	ADCY2,PRKCA
3.401e-03	-5.68	Downregulation of ERBB2 signaling	REACTOME pathways	R-HSA-8863795	30	2	10285	30	NRG3,ERBB4
3.404e-03	-5.68	cellular response to endogenous stimulus	biological process	GO:0071495	1135	9	18204	50	SORBS1,SLC1A2,NTRK2,RYR3,SOX5,ERBB4,TNC,NTRK3,ATP1A2
3.444e-03	-5.67	NTKRECEPTOR3	prints domains	PR01942	1	1	5227	18	NTRK3
3.444e-03	-5.67	NTKRECEPTOR2	prints domains	PR01941	1	1	5227	18	NTRK2
3.501e-03	-5.65	purine ribonucleotide binding	molecular function	GO:0032555	1871	12	18094	49	KALRN,PRKCA,ERBB4,ADCY2,NAV2,ATP1A2,CAMK2G,NTRK2,NTRK3,RPS6KA2,DGKG,DCLK2
3.519e-03	-5.65	EGF-like_dom	interpro domains	IPR000742	232	4	18521	50	TNC,LRP1B,NRG3,NRXN1
3.549e-03	-5.64	PROTEIN_KINASE_ST	prosite domains	PS00108	308	5	12186	41	PRKCA,RPS6KA2,KALRN,DCLK2,CAMK2G
3.590e-03	-5.63	SCRIB (scribble planar cell polarity protein)	protein interactions	23513	245	4	19454	50	PARD3,NTRK3,PRKCA,RPS6KA2
3.619e-03	-5.62	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-NK-T_cell_lymphoma	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-NK-T_cell_lymphoma	217	4	16828	49	RFX4,DTNA,MGAT4C,NAV2
3.621e-03	-5.62	meninges	COSMIC cancer mutations	meninges	514	6	16828	49	RPS6KA2,NAV2,FMN2,NTRK3,RYR3,SYNE1
3.621e-03	-5.62	meningioma	COSMIC cancer mutations	meningioma	514	6	16828	49	RPS6KA2,NAV2,FMN2,RYR3,NTRK3,SYNE1
3.650e-03	-5.61	lower_third	COSMIC cancer mutations	lower_third	7961	33	16828	49	NRG3,TRPM3,RPS6KA2,FMN2,DGKG,PRKCA,RYR3,NTRK3,NEBL,SORBS1,SYNE1,PARD3,MACF1,DCLK2,NAV2,KALRN,RORA,MGAT4C,HPSE2,ERBB4,NRXN1,SLC4A4,NPAS3,GPC5,CDH20,LRP1B,ADCY2,PSD2,CTNND2,ATP1A2,TNC,NTRK2,SOX5
3.697e-03	-5.60	response to auditory stimulus	biological process	GO:0010996	33	2	18204	50	ATP1A2,NRXN1
3.705e-03	-5.60	DELLA	smart domains	SM01129	1	1	9717	36	MACF1
3.709e-03	-5.60	Signaling by EGFR	REACTOME pathways	R-HSA-177929	364	5	10285	30	NRG3,ERBB4,CAMK2G,ADCY2,PRKCA
3.771e-03	-5.58	ribonucleotide binding	molecular function	GO:0032553	1888	12	18094	49	ERBB4,PRKCA,KALRN,ADCY2,ATP1A2,NAV2,DCLK2,DGKG,NTRK2,RPS6KA2,NTRK3,CAMK2G
3.792e-03	-5.57	Pkinase_C	interpro domains	IPR017892	34	2	18521	50	PRKCA,RPS6KA2
3.803e-03	-5.57	anion binding	molecular function	GO:0043168	2412	14	18094	49	ADCY2,PITPNC1,KALRN,PRKCA,ERBB4,RPS6KA2,NTRK2,NTRK3,CAMK2G,PARD3,DGKG,DCLK2,NAV2,ATP1A2
3.833e-03	-5.56	PROTEIN_KINASE_TYR	prosite domains	PS00109	94	3	12186	41	ERBB4,NTRK2,NTRK3
3.833e-03	-5.56	synaptic membrane	cellular component	GO:0097060	400	5	19108	50	ERBB4,SYNE1,GPM6A,SLC1A2,NRXN1
3.857e-03	-5.56	SLC5A5 (solute carrier family 5 member 5)	protein interactions	6528	36	2	19454	50	SFXN5,CAMK2G
3.864e-03	-5.56	Glutamate Binding, Activation of AMPA Receptors and Synaptic Plasticity	REACTOME pathways	R-HSA-399721	32	2	10285	30	CAMK2G,PRKCA
3.864e-03	-5.56	Trafficking of AMPA receptors	REACTOME pathways	R-HSA-399719	32	2	10285	30	PRKCA,CAMK2G
3.908e-03	-5.54	monoatomic ion transmembrane transporter activity	molecular function	GO:0015075	752	7	18094	49	SFXN5,TRPM3,GPM6A,SLC4A4,SLC1A2,RYR3,ATP1A2
3.910e-03	-5.54	calcium channel activity	molecular function	GO:0005262	117	3	18094	49	GPM6A,TRPM3,RYR3
3.912e-03	-5.54	Ig_sub2	interpro domains	IPR003598	239	4	18521	50	LSAMP,NTM,NTRK2,KALRN
3.930e-03	-5.54	oesophagus-lower_third-carcinoma-adenocarcinoma	COSMIC cancer mutations	oesophagus-lower_third-carcinoma-adenocarcinoma	6302	28	16828	49	SYNE1,SORBS1,PARD3,RORA,KALRN,MACF1,MGAT4C,TRPM3,NRG3,PRKCA,RYR3,NTRK3,RPS6KA2,FMN2,DGKG,NEBL,PSD2,CTNND2,TNC,SOX5,NTRK2,NRXN1,NPAS3,ERBB4,CDH20,GPC5,LRP1B,ADCY2
3.939e-03	-5.54	Pkinase_C	pfam domains	PF00433	34	2	17795	49	RPS6KA2,PRKCA
3.969e-03	-5.53	NCK2 (NCK adaptor protein 2)	protein interactions	8440	252	4	19454	50	ERBB4,SORBS1,NTRK2,NTRK3
4.024e-03	-5.52	DAP12 interactions	REACTOME pathways	R-HSA-2172127	371	5	10285	30	ADCY2,PRKCA,CAMK2G,NRG3,ERBB4
4.032e-03	-5.51	haematopoietic_and_lymphoid_tissue	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue	14368	48	16828	49	GLIS3,SFXN5,NRG3,NKAIN3,RYR3,PRKCA,NTM,DGKG,FMN2,RPS6KA2,DTNA,SYNE1,PARD3,SLC14A1,MSI2,KALRN,DCLK2,PITPNC1,MGAT4C,SLC4A4,NRXN1,ERBB4,ADCY2,GPC5,LRP1B,PSD2,ATP1A2,CAMK2G,GFAP,TRPM3,NTRK3,NEBL,RFX4,SORBS1,SLC1A2,RORA,GPM6A,NAV2,MACF1,HPSE2,ABLIM1,NPAS3,LSAMP,CDH20,CTNND2,TNC,SOX5,NTRK2
4.071e-03	-5.50	PRRG4 (proline rich and Gla domain 4)	protein interactions	79056	37	2	19454	50	ERBB4,NEBL
4.071e-03	-5.50	MAGI2 (membrane associated guanylate kinase, WW and PDZ domain containing 2)	protein interactions	9863	37	2	19454	50	CTNND2,ERBB4
4.102e-03	-5.50	Ig_sub	interpro domains	IPR003599	394	5	18521	50	KALRN,NTRK2,NTM,LSAMP,NTRK3
4.112e-03	-5.49	FYN (FYN proto-oncogene, Src family tyrosine kinase)	protein interactions	2534	414	5	19454	50	KALRN,NTRK2,RPS6KA2,CTNND2,ERBB4
4.117e-03	-5.49	NK-T_cell_lymphoma	COSMIC cancer mutations	NK-T_cell_lymphoma	225	4	16828	49	DTNA,RFX4,MGAT4C,NAV2
4.128e-03	-5.49	EGF_3	prosite domains	PS50026	196	4	12186	41	NRG3,TNC,NRXN1,LRP1B
4.140e-03	-5.49	salivary_gland-submandibular-carcinoma-adenoid_cystic_carcinoma	COSMIC cancer mutations	salivary_gland-submandibular-carcinoma-adenoid_cystic_carcinoma	33	2	16828	49	LRP1B,NAV2
4.151e-03	-5.48	astrocytoma_Grade_III	COSMIC cancer mutations	astrocytoma_Grade_III	1544	11	16828	49	RYR3,PRKCA,NAV2,HPSE2,ADCY2,GPC5,LRP1B,TRPM3,ERBB4,NRG3,PARD3
4.215e-03	-5.47	glial cell projection	cellular component	GO:0097386	37	2	19108	50	GFAP,SLC1A2
4.251e-03	-5.46	TYRKINASE	prints domains	PR00109	98	3	5227	18	NTRK3,NTRK2,ERBB4
4.255e-03	-5.46	PDLIM7 (PDZ and LIM domain 7)	protein interactions	9260	257	4	19454	50	ABLIM1,PRKCA,GFAP,PARD3
4.261e-03	-5.46	Signaling by PDGF	REACTOME pathways	R-HSA-186797	376	5	10285	30	ERBB4,NRG3,ADCY2,PRKCA,CAMK2G
4.268e-03	-5.46	proteoglycan binding	molecular function	GO:0043394	36	2	18094	49	TNC,HPSE2
4.290e-03	-5.45	RORA (RAR related orphan receptor A)	protein interactions	6095	38	2	19454	50	RORA,GFAP
4.308e-03	-5.45	GnRH signaling pathway	KEGG pathways	hsa04912	92	3	7161	26	PRKCA,CAMK2G,ADCY2
4.308e-03	-5.45	GnRH signaling pathway	KEGG pathways	ko04912	92	3	7161	26	CAMK2G,PRKCA,ADCY2
4.335e-03	-5.44	kidney-other-neoplasm	COSMIC cancer mutations	kidney-other-neoplasm	10653	40	16828	49	FMN2,DGKG,PRKCA,NTRK3,RYR3,DTNA,RFX4,NEBL,NRG3,SFXN5,TRPM3,GFAP,NKAIN3,MACF1,GPM6A,NAV2,KALRN,RORA,ABLIM1,MGAT4C,HPSE2,SLC1A2,SORBS1,SYNE1,PARD3,LRP1B,CDH20,GPC5,ADCY2,ERBB4,NRXN1,NPAS3,LSAMP,NTRK2,CAMK2G,SOX5,PSD2,CTNND2,ATP1A2,TNC
4.344e-03	-5.44	glutamatergic synapse	cellular component	GO:0098978	412	5	19108	50	NRG3,SLC1A2,ERBB4,GPM6A,PSD2
4.354e-03	-5.44	DAG and IP3 signaling	REACTOME pathways	R-HSA-1489509	34	2	10285	30	ADCY2,PRKCA
4.370e-03	-5.43	regulation of nervous system process	biological process	GO:0031644	120	3	18204	50	NRXN1,SYNE1,PARD3
4.370e-03	-5.43	striated muscle contraction	biological process	GO:0006941	120	3	18204	50	DTNA,RYR3,ATP1A2
4.448e-03	-5.42	central_nervous_system-brainstem-glioma-oligoastrocytoma_Grade_III	COSMIC cancer mutations	central_nervous_system-brainstem-glioma-oligoastrocytoma_Grade_III	114	3	16828	49	SLC1A2,RYR3,SOX5
4.472e-03	-5.41	regulation of signaling	biological process	GO:0023051	3534	18	18204	50	SYNE1,PSD2,CTNND2,NTRK2,NTRK3,GFAP,DGKG,ERBB4,MACF1,SORBS1,PRKCA,NDRG2,ATP1A2,NRG3,KALRN,NRXN1,RORA,GPC5
4.494e-03	-5.41	DIRAS3 (DIRAS family GTPase 3)	protein interactions	9077	261	4	19454	50	FMN2,PARD3,DTNA,MACF1
4.569e-03	-5.39	regulation of system process	biological process	GO:0044057	571	6	18204	50	CAMK2G,NRXN1,PARD3,ATP1A2,PRKCA,SYNE1
4.571e-03	-5.39	regulation of cell communication	biological process	GO:0010646	3541	18	18204	50	GPC5,NRXN1,KALRN,RORA,NRG3,ATP1A2,NDRG2,SORBS1,PRKCA,MACF1,ERBB4,GFAP,DGKG,NTRK3,NTRK2,PSD2,CTNND2,SYNE1
4.603e-03	-5.38	organic anion transport	biological process	GO:0015711	398	5	18204	50	SLC1A2,NTRK2,SFXN5,GFAP,SLC4A4
4.605e-03	-5.38	regulation of synapse organization	biological process	GO:0050807	246	4	18204	50	GPM6A,CTNNA2,NTRK2,NRXN1
4.631e-03	-5.38	positive regulation of glucose import	biological process	GO:0046326	37	2	18204	50	SLC1A2,SORBS1
4.723e-03	-5.36	transporter activity	molecular function	GO:0005215	1211	9	18094	49	PITPNC1,TRPM3,SLC14A1,GPM6A,SFXN5,RYR3,ATP1A2,SLC1A2,SLC4A4
4.740e-03	-5.35	cytoskeletal protein binding	molecular function	GO:0008092	989	8	18094	49	ABLIM1,CTNNA2,FMN2,NEBL,SYNE1,DCLK2,MACF1,SORBS1
4.816e-03	-5.34	gallbladder	COSMIC cancer mutations	gallbladder	2821	16	16828	49	NKAIN3,TRPM3,SLC4A4,NRG3,ERBB4,LRP1B,RYR3,NTRK3,FMN2,TNC,PARD3,SYNE1,PSD2,CTNND2,PITPNC1,MACF1
4.816e-03	-5.34	biliary_tract-gallbladder-carcinoma-adenocarcinoma	COSMIC cancer mutations	biliary_tract-gallbladder-carcinoma-adenocarcinoma	2821	16	16828	49	PSD2,SYNE1,CTNND2,PARD3,TNC,MACF1,PITPNC1,TRPM3,SLC4A4,ERBB4,NRG3,NKAIN3,RYR3,NTRK3,FMN2,LRP1B
4.872e-03	-5.32	EGFR interacts with phospholipase C-gamma	REACTOME pathways	R-HSA-212718	36	2	10285	30	ADCY2,PRKCA
4.872e-03	-5.32	PLC-gamma1 signalling	REACTOME pathways	R-HSA-167021	36	2	10285	30	ADCY2,PRKCA
4.880e-03	-5.32	amino acid import across plasma membrane	biological process	GO:0089718	38	2	18204	50	SLC1A2,GFAP
4.912e-03	-5.32	submandibular	COSMIC cancer mutations	submandibular	36	2	16828	49	NAV2,LRP1B
4.934e-03	-5.31	VCL (vinculin)	protein interactions	7414	268	4	19454	50	MACF1,SORBS1,PRKCA,NEBL
4.940e-03	-5.31	inorganic cation transmembrane transporter activity	molecular function	GO:0022890	589	6	18094	49	ATP1A2,RYR3,SLC1A2,GPM6A,TRPM3,SLC4A4
4.966e-03	-5.31	cellular component biogenesis	biological process	GO:0044085	2716	15	18204	50	CDH20,SLC1A2,GPM6A,PARD3,NEBL,TRPM3,ERBB4,RYR3,RFX4,SORBS1,PRKCA,ABLIM1,FMN2,NRG3,NRXN1
4.989e-03	-5.30	SH3 Domains	gene3d domains	2.30.30.40	223	4	14470	45	NEBL,MACF1,KALRN,SORBS1
4.997e-03	-5.30	Inflammatory mediator regulation of TRP channels	KEGG pathways	hsa04750	97	3	7161	26	ADCY2,CAMK2G,PRKCA
4.997e-03	-5.30	Inflammatory mediator regulation of TRP channels	KEGG pathways	ko04750	97	3	7161	26	PRKCA,CAMK2G,ADCY2
5.014e-03	-5.30	regulation of synapse structure or activity	biological process	GO:0050803	252	4	18204	50	NRXN1,NTRK2,GPM6A,CTNNA2
5.020e-03	-5.29	localization	biological process	GO:0051179	4474	21	18204	50	SFXN5,LRP1B,SLC14A1,SLC1A2,PITPNC1,NTRK2,SYNE1,SLC4A4,TRPM3,GFAP,ERBB4,CAMK2G,PARD3,GPM6A,RYR3,MACF1,NRXN1,KALRN,FMN2,ATP1A2,DCLK2
5.065e-03	-5.29	WDR6 (WD repeat domain 6)	protein interactions	11180	270	4	19454	50	NTRK2,NTRK3,PARD3,RPS6KA2
5.094e-03	-5.28	SRC (SRC proto-oncogene, non-receptor tyrosine kinase)	protein interactions	6714	624	6	19454	50	SORBS1,SLC14A1,ERBB4,PRKCA,GFAP,MSI2
5.118e-03	-5.28	cell-cell junction assembly	biological process	GO:0007043	127	3	18204	50	CDH20,PRKCA,PARD3
5.127e-03	-5.27	EF-hand-dom_pair	interpro domains	IPR011992	258	4	18521	50	MACF1,RYR3,DTNA,DGKG
5.134e-03	-5.27	Grin2c (glutamate ionotropic receptor NMDA type subunit 2C)	protein interactions	24411	2	1	19454	50	PRKCA
5.134e-03	-5.27	Zmym2 (zinc finger, MYM-type 2)	protein interactions	76007	2	1	19454	50	GLIS3
5.134e-03	-5.27	EST1 (Est1p)	protein interactions	850934	2	1	19454	50	NAV2
5.134e-03	-5.27	Kdm4c (lysine (K)-specific demethylase 4C)	protein interactions	76804	2	1	19454	50	GLIS3
5.134e-03	-5.27	numb (numb)	protein interactions	34263	2	1	19454	50	PRKCA
5.134e-03	-5.27	URA1 (dihydroorotate dehydrogenase)	protein interactions	853664	2	1	19454	50	GFAP
5.134e-03	-5.27	cdh11.S (cadherin 11 S homeolog)	protein interactions	100337621	2	1	19454	50	ERBB4
5.134e-03	-5.27	cellular response to alkaloid	biological process	GO:0071312	39	2	18204	50	SLC1A2,RYR3
5.134e-03	-5.27	olfactory lobe development	biological process	GO:0021988	39	2	18204	50	ATP1A2,ERBB4
5.141e-03	-5.27	Post NMDA receptor activation events	REACTOME pathways	R-HSA-438064	37	2	10285	30	RPS6KA2,CAMK2G
5.198e-03	-5.26	RDX (radixin)	protein interactions	5962	272	4	19454	50	NTRK3,MACF1,ABLIM1,NEBL
5.198e-03	-5.26	purine nucleotide binding	molecular function	GO:0017076	1964	12	18094	49	NAV2,ATP1A2,RPS6KA2,NTRK2,NTRK3,CAMK2G,DGKG,DCLK2,PRKCA,KALRN,ERBB4,ADCY2
5.220e-03	-5.26	GRIA2 (glutamate ionotropic receptor AMPA type subunit 2)	protein interactions	2891	42	2	19454	50	PRKCA,GPM6A
5.230e-03	-5.25	Laminin	gene3d domains	2.10.25.10	226	4	14470	45	TNC,NRG3,NRXN1,LRP1B
5.231e-03	-5.25	glial cell development	biological process	GO:0021782	128	3	18204	50	GFAP,NTRK2,PARD3
5.283e-03	-5.24	positive regulation of cell population proliferation	biological process	GO:0008284	992	8	18204	50	SYNE1,NTRK3,GFAP,PRKCA,NTRK2,HPSE2,TNC,ERBB4
5.328e-03	-5.23	establishment of localization	biological process	GO:0051234	3887	19	18204	50	PARD3,GPM6A,SLC4A4,TRPM3,GFAP,ERBB4,CAMK2G,LRP1B,SLC14A1,SFXN5,SLC1A2,NTRK2,PITPNC1,ATP1A2,FMN2,NRXN1,KALRN,RYR3,MACF1
5.356e-03	-5.23	lung-middle_lobe-carcinoma-adenocarcinoma	COSMIC cancer mutations	lung-middle_lobe-carcinoma-adenocarcinoma	1368	10	16828	49	HPSE2,LRP1B,RYR3,NTRK3,MACF1,ATP1A2,SYNE1,TRPM3,CTNND2,ERBB4
5.373e-03	-5.23	positive regulation of multicellular organismal process	biological process	GO:0051240	1691	11	18204	50	PRKCA,NTRK2,SFXN5,MACF1,GFAP,NRXN1,SOX5,RORA,ERBB4,ATP1A2,PARD3
5.392e-03	-5.22	Par3/HAL_N	interpro domains	IPR021922	2	1	18521	50	PARD3
5.392e-03	-5.22	Glyco_hydro_79	interpro domains	IPR005199	2	1	18521	50	HPSE2
5.392e-03	-5.22	Kalirin_TRIO_SH3_2	interpro domains	IPR047053	2	1	18521	50	KALRN
5.392e-03	-5.22	MSI_RRM2	interpro domains	IPR034126	2	1	18521	50	MSI2
5.392e-03	-5.22	Distrobrevin	interpro domains	IPR017432	2	1	18521	50	DTNA
5.392e-03	-5.22	Kalirin_TRIO_SH3_1	interpro domains	IPR028570	2	1	18521	50	KALRN
5.392e-03	-5.22	Kalirin_TRIO_PH_1	interpro domains	IPR047054	2	1	18521	50	KALRN
5.392e-03	-5.22	Anc-1/SYNE1/2-like	interpro domains	IPR039906	2	1	18521	50	SYNE1
5.392e-03	-5.22	Formin_Cappuccino_subfam	interpro domains	IPR001265	2	1	18521	50	FMN2
5.392e-03	-5.22	Urea_transporter	interpro domains	IPR004937	2	1	18521	50	SLC14A1
5.392e-03	-5.22	LRP1-like_beta_prop	interpro domains	IPR032485	2	1	18521	50	LRP1B
5.395e-03	-5.22	cyclic purine nucleotide metabolic process	biological process	GO:0052652	40	2	18204	50	RORA,ADCY2
5.409e-03	-5.22	histone H3T6 kinase activity	molecular function	GO:0035403	2	1	18094	49	PRKCA
5.409e-03	-5.22	heparanase activity	molecular function	GO:0030305	2	1	18094	49	HPSE2
5.409e-03	-5.22	calcium,diacylglycerol-dependent serine/threonine kinase activity	molecular function	GO:0004698	2	1	18094	49	PRKCA
5.462e-03	-5.21	lung-carcinoma-adenocarcinoma	COSMIC cancer mutations	lung-carcinoma-adenocarcinoma	15133	49	16828	49	NRG3,GLIS3,SFXN5,NKAIN3,DGKG,FMN2,RPS6KA2,RYR3,PRKCA,NTM,DTNA,SYNE1,MSI2,SLC14A1,PARD3,DCLK2,KALRN,MGAT4C,PITPNC1,ERBB4,SLC4A4,NRXN1,ADCY2,LRP1B,GPC5,NDRG2,PSD2,ATP1A2,CAMK2G,GFAP,TRPM3,NTRK3,NEBL,RFX4,SORBS1,SLC1A2,NAV2,GPM6A,MACF1,RORA,ABLIM1,HPSE2,NPAS3,LSAMP,CDH20,CTNND2,TNC,NTRK2,SOX5
5.466e-03	-5.21	C2CD4B (C2 calcium dependent domain containing 4B)	protein interactions	388125	43	2	19454	50	MACF1,LRP1B
5.486e-03	-5.21	mesenchymal-epithelial cell signaling involved in prostate gland development	biological process	GO:0060739	2	1	18204	50	TNC
5.486e-03	-5.21	negative regulation of mini excitatory postsynaptic potential	biological process	GO:0061886	2	1	18204	50	SYNE1
5.486e-03	-5.21	positive regulation of dense core granule biogenesis	biological process	GO:2000707	2	1	18204	50	PRKCA
5.486e-03	-5.21	establishment of planar polarity involved in nephron morphogenesis	biological process	GO:0072046	2	1	18204	50	ERBB4
5.493e-03	-5.20	PK_Tyr_Ser-Thr	pfam domains	PF07714	130	3	17795	49	NTRK2,NTRK3,ERBB4
5.500e-03	-5.20	Glyco_hydro_79n	pfam domains	PF03662	2	1	17795	49	HPSE2
5.500e-03	-5.20	DUF5050	pfam domains	PF16472	2	1	17795	49	LRP1B
5.500e-03	-5.20	Par3_HAL_N_term	pfam domains	PF12053	2	1	17795	49	PARD3
5.500e-03	-5.20	SH3-RhoG_link	pfam domains	PF16609	2	1	17795	49	KALRN
5.500e-03	-5.20	UT	pfam domains	PF03253	2	1	17795	49	SLC14A1
5.547e-03	-5.19	Ser-Thr/Tyr_kinase_cat_dom	interpro domains	IPR001245	133	3	18521	50	NTRK2,ERBB4,NTRK3
5.595e-03	-5.19	Melanogenesis	KEGG pathways	ko04916	101	3	7161	26	ADCY2,PRKCA,CAMK2G
5.595e-03	-5.19	Melanogenesis	KEGG pathways	hsa04916	101	3	7161	26	ADCY2,PRKCA,CAMK2G
5.658e-03	-5.17	sarcoplasmic reticulum membrane	cellular component	GO:0033017	43	2	19108	50	CAMK2G,RYR3
5.662e-03	-5.17	cyclic nucleotide metabolic process	biological process	GO:0009187	41	2	18204	50	ADCY2,RORA
5.696e-03	-5.17	ARHGAP32 (Rho GTPase activating protein 32)	protein interactions	9743	141	3	19454	50	PARD3,NTRK3,NTRK2
5.696e-03	-5.17	LLGL1 (LLGL scribble cell polarity complex component 1)	protein interactions	3996	141	3	19454	50	NTRK2,NTRK3,PARD3
5.734e-03	-5.16	transport	biological process	GO:0006810	3615	18	18204	50	MACF1,RYR3,ATP1A2,FMN2,KALRN,NRXN1,NTRK2,PITPNC1,SLC1A2,SFXN5,SLC14A1,LRP1B,GPM6A,TRPM3,GFAP,SLC4A4,CAMK2G,ERBB4
5.744e-03	-5.16	Proteoglycans in cancer	KEGG pathways	ko05205	203	4	7161	26	HPSE2,ERBB4,CAMK2G,PRKCA
5.744e-03	-5.16	Proteoglycans in cancer	KEGG pathways	hsa05205	203	4	7161	26	CAMK2G,PRKCA,HPSE2,ERBB4
5.752e-03	-5.16	middle_lobe	COSMIC cancer mutations	middle_lobe	1382	10	16828	49	MACF1,NTRK3,RYR3,LRP1B,HPSE2,ERBB4,TRPM3,SYNE1,CTNND2,ATP1A2
5.755e-03	-5.16	clear_cell_renal_cell_carcinoma	COSMIC cancer mutations	clear_cell_renal_cell_carcinoma	13924	47	16828	49	TNC,CTNND2,NTRK2,SOX5,LSAMP,NPAS3,CDH20,SORBS1,SLC1A2,ABLIM1,HPSE2,NAV2,GPM6A,MACF1,RORA,GFAP,TRPM3,NEBL,NTRK3,ATP1A2,PSD2,CAMK2G,ERBB4,SLC4A4,NRXN1,ADCY2,LRP1B,GPC5,NDRG2,MSI2,SLC14A1,PARD3,SYNE1,MGAT4C,PITPNC1,DCLK2,KALRN,NKAIN3,NRG3,GLIS3,SFXN5,DTNA,DGKG,FMN2,RPS6KA2,RYR3,PRKCA
5.755e-03	-5.16	kidney-carcinoma-clear_cell_renal_cell_carcinoma	COSMIC cancer mutations	kidney-carcinoma-clear_cell_renal_cell_carcinoma	13924	47	16828	49	NTRK2,SOX5,TNC,CTNND2,CDH20,LSAMP,NPAS3,ABLIM1,HPSE2,NAV2,GPM6A,MACF1,RORA,SORBS1,SLC1A2,NEBL,NTRK3,GFAP,TRPM3,CAMK2G,ATP1A2,PSD2,ADCY2,LRP1B,GPC5,NDRG2,ERBB4,SLC4A4,NRXN1,MGAT4C,PITPNC1,DCLK2,KALRN,MSI2,PARD3,SLC14A1,SYNE1,DTNA,FMN2,DGKG,RPS6KA2,RYR3,PRKCA,NKAIN3,NRG3,GLIS3,SFXN5
5.766e-03	-5.16	axon development	biological process	GO:0061564	420	5	18204	50	TNC,NRXN1,KALRN,CTNNA2,PARD3
5.867e-03	-5.14	protein serine/threonine kinase activity	molecular function	GO:0004674	428	5	18094	49	RPS6KA2,CAMK2G,PRKCA,KALRN,DCLK2
5.935e-03	-5.13	Schwann cell development	biological process	GO:0014044	42	2	18204	50	PARD3,NTRK2
5.946e-03	-5.13	calcium ion transmembrane transporter activity	molecular function	GO:0015085	136	3	18094	49	TRPM3,GPM6A,RYR3
6.035e-03	-5.11	Ig-like_dom	interpro domains	IPR007110	432	5	18521	50	LSAMP,NTRK3,KALRN,NTRK2,NTM
6.037e-03	-5.11	Calml3 (calmodulin-like 3)	protein interactions	70405	144	3	19454	50	ABLIM1,CAMK2G,MACF1
6.090e-03	-5.10	monoatomic ion transmembrane transport	biological process	GO:0034220	804	7	18204	50	SLC4A4,TRPM3,GPM6A,ATP1A2,SFXN5,SLC1A2,RYR3
6.102e-03	-5.10	sarcolemma	cellular component	GO:0042383	142	3	19108	50	RYR3,ATP1A2,DTNA
6.210e-03	-5.08	Vinculin, Vh2 four-helix bundle	gene3d domains	1.20.120.810	2	1	14470	45	CTNNA2
6.210e-03	-5.08	-	gene3d domains	6.20.350.10	2	1	14470	45	RYR3
6.272e-03	-5.07	DSCR9 (Down syndrome critical region 9)	protein interactions	257203	146	3	19454	50	KALRN,SYNE1,MACF1
6.285e-03	-5.07	Activation of NMDA receptor upon glutamate binding and postsynaptic events	REACTOME pathways	R-HSA-442755	41	2	10285	30	RPS6KA2,CAMK2G
6.345e-03	-5.06	VEGFR2 mediated cell proliferation	REACTOME pathways	R-HSA-5218921	258	4	10285	30	PRKCA,CAMK2G,ERBB4,NRG3
6.348e-03	-5.06	VASP (vasodilator stimulated phosphoprotein)	protein interactions	7408	288	4	19454	50	FMN2,PARD3,SORBS1,NEBL
6.405e-03	-5.05	SH3	prosite domains	PS50002	222	4	12186	41	MACF1,NEBL,KALRN,SORBS1
6.420e-03	-5.05	trans-synaptic signaling	biological process	GO:0099537	431	5	18204	50	RPS6KA2,DTNA,NRXN1,NTRK2,SLC1A2
6.435e-03	-5.05	cytoskeleton organization	biological process	GO:0007010	1251	9	18204	50	ABLIM1,SORBS1,CTNNA2,MACF1,GFAP,NEBL,PARD3,FMN2,DCLK2
6.454e-03	-5.04	leg	COSMIC cancer mutations	leg	969	8	16828	49	FMN2,NTRK3,NTM,NEBL,LRP1B,NRG3,SLC4A4,SYNE1
6.493e-03	-5.04	spleen	COSMIC cancer mutations	spleen	408	5	16828	49	LRP1B,ADCY2,NTM,SYNE1,SORBS1
6.498e-03	-5.04	positive regulation of glucose transmembrane transport	biological process	GO:0010828	44	2	18204	50	SLC1A2,SORBS1
6.500e-03	-5.04	CNTN1 (contactin 1)	protein interactions	1272	47	2	19454	50	TNC,GPM6A
6.500e-03	-5.04	GRIA1 (glutamate ionotropic receptor AMPA type subunit 1)	protein interactions	2890	47	2	19454	50	PRKCA,CAMK2G
6.512e-03	-5.03	PKP4 (plakophilin 4)	protein interactions	8502	148	3	19454	50	RPS6KA2,PARD3,NTRK3
6.698e-03	-5.01	protein tyrosine kinase activity	molecular function	GO:0004713	142	3	18094	49	ERBB4,NTRK2,NTRK3
6.702e-03	-5.01	neurotransmitter transport	biological process	GO:0006836	140	3	18204	50	ATP1A2,NRXN1,SLC1A2
6.772e-03	-4.99	PAM (peptidylglycine alpha-amidating monooxygenase)	protein interactions	5066	48	2	19454	50	PRKCA,KALRN
6.788e-03	-4.99	acidic amino acid transport	biological process	GO:0015800	45	2	18204	50	NTRK2,SLC1A2
6.817e-03	-4.99	monoatomic cation transmembrane transporter activity	molecular function	GO:0008324	630	6	18094	49	SLC4A4,TRPM3,GPM6A,SLC1A2,RYR3,ATP1A2
6.853e-03	-4.98	cell-cell signaling	biological process	GO:0007267	822	7	18204	50	TNC,CAMK2G,NRXN1,DTNA,NTRK2,SLC1A2,RPS6KA2
6.870e-03	-4.98	uveal_tract	COSMIC cancer mutations	uveal_tract	587	6	16828	49	ADCY2,NTRK3,CTNND2,KALRN,TRPM3,MACF1
6.875e-03	-4.98	transmembrane transport	biological process	GO:0055085	1264	9	18204	50	RYR3,SLC14A1,SFXN5,SLC1A2,ATP1A2,GPM6A,SLC4A4,TRPM3,GFAP
6.876e-03	-4.98	FORMIN	prints domains	PR00828	2	1	5227	18	FMN2
6.881e-03	-4.98	TNIK (TRAF2 and NCK interacting kinase)	protein interactions	23043	151	3	19454	50	MACF1,SYNE1,NTRK3
6.881e-03	-4.98	NISCH (nischarin)	protein interactions	11188	151	3	19454	50	NTRK2,NTRK3,RPS6KA2
6.919e-03	-4.97	membrane raft	cellular component	GO:0045121	290	4	19108	50	SLC1A2,ATP1A2,SORBS1,ADCY2
6.932e-03	-4.97	embryonal	COSMIC cancer mutations	embryonal	2659	15	16828	49	GLIS3,NPAS3,TRPM3,ADCY2,LRP1B,RYR3,FMN2,TNC,CTNND2,SYNE1,SORBS1,RORA,NAV2,CAMK2G,MACF1
6.932e-03	-4.97	soft_tissue-striated_muscle-rhabdomyosarcoma-embryonal	COSMIC cancer mutations	soft_tissue-striated_muscle-rhabdomyosarcoma-embryonal	2659	15	16828	49	NPAS3,GLIS3,TRPM3,FMN2,RYR3,ADCY2,LRP1B,SORBS1,CTNND2,SYNE1,TNC,NAV2,CAMK2G,MACF1,RORA
6.994e-03	-4.96	intracellular signal transduction	biological process	GO:0035556	1505	10	18204	50	RYR3,RPS6KA2,ADCY2,PRKCA,DCLK2,ATP1A2,FMN2,NRG3,KALRN,DGKG
7.007e-03	-4.96	STMN1 (stathmin 1)	protein interactions	3925	152	3	19454	50	CAMK2G,PRKCA,DTNA
7.086e-03	-4.95	membrane microdomain	cellular component	GO:0098857	292	4	19108	50	SORBS1,ADCY2,SLC1A2,ATP1A2
7.095e-03	-4.95	enzyme-linked receptor protein signaling pathway	biological process	GO:0007167	626	6	18204	50	NTRK2,SORBS1,NRG3,NTRK3,ERBB4,KALRN
7.119e-03	-4.94	oligoastrocytoma_Grade_III	COSMIC cancer mutations	oligoastrocytoma_Grade_III	263	4	16828	49	SYNE1,RYR3,SOX5,SLC1A2
7.191e-03	-4.93	cell morphogenesis involved in neuron differentiation	biological process	GO:0048667	443	5	18204	50	NRXN1,KALRN,PARD3,CTNNA2,CTNND2
7.213e-03	-4.93	skin-acral-malignant_melanoma	COSMIC cancer mutations	skin-acral-malignant_melanoma	264	4	16828	49	CDH20,PARD3,FMN2,PSD2
7.330e-03	-4.92	C1GALT1 (core 1 synthase, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1)	protein interactions	56913	50	2	19454	50	SLC14A1,NTRK3
7.386e-03	-4.91	regulation of neuron migration	biological process	GO:2001222	47	2	18204	50	NRG3,CTNNA2
7.386e-03	-4.91	Schwann cell differentiation	biological process	GO:0014037	47	2	18204	50	NTRK2,PARD3
7.404e-03	-4.91	large_intestine-adenoma	COSMIC cancer mutations	large_intestine-adenoma	266	4	16828	49	SOX5,RYR3,LRP1B,CDH20
7.436e-03	-4.90	RET signaling	REACTOME pathways	R-HSA-8853659	270	4	10285	30	ERBB4,NRG3,PRKCA,CAMK2G
7.452e-03	-4.90	Cholinergic synapse	KEGG pathways	hsa04725	112	3	7161	26	CAMK2G,PRKCA,ADCY2
7.521e-03	-4.89	adult behavior	biological process	GO:0030534	146	3	18204	50	SLC1A2,NRXN1,ATP1A2
7.525e-03	-4.89	CEP19 (centrosomal protein 19)	protein interactions	84984	156	3	19454	50	FMN2,PARD3,ABLIM1
7.585e-03	-4.88	oesophagus-lower_third-carcinoma-squamous_cell_carcinoma	COSMIC cancer mutations	oesophagus-lower_third-carcinoma-squamous_cell_carcinoma	3507	18	16828	49	HPSE2,DCLK2,MACF1,NAV2,ATP1A2,PARD3,SYNE1,CTNND2,GPC5,LRP1B,ADCY2,DGKG,FMN2,RYR3,ERBB4,TRPM3,SLC4A4,NPAS3
7.592e-03	-4.88	haematopoietic_and_lymphoid_tissue-small_intestine-lymphoid_neoplasm-enteropathy_type_T_cell_lymphoma	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue-small_intestine-lymphoid_neoplasm-enteropathy_type_T_cell_lymphoma	45	2	16828	49	MGAT4C,MACF1
7.592e-03	-4.88	enteropathy_type_T_cell_lymphoma	COSMIC cancer mutations	enteropathy_type_T_cell_lymphoma	45	2	16828	49	MGAT4C,MACF1
7.599e-03	-4.88	acral	COSMIC cancer mutations	acral	268	4	16828	49	CDH20,PARD3,FMN2,PSD2
7.617e-03	-4.88	LINGO1 (leucine rich repeat and Ig domain containing 1)	protein interactions	84894	51	2	19454	50	NTRK3,NTM
7.617e-03	-4.88	FAM171B (family with sequence similarity 171 member B)	protein interactions	165215	51	2	19454	50	NTRK2,PARD3
7.691e-03	-4.87	Spop (speckle-type BTB/POZ protein)	protein interactions	20747	3	1	19454	50	GLIS3
7.691e-03	-4.87	NRG3 (neuregulin 3)	protein interactions	10718	3	1	19454	50	ERBB4
7.691e-03	-4.87	QRFPR (pyroglutamylated RFamide peptide receptor)	protein interactions	84109	3	1	19454	50	NTM
7.691e-03	-4.87	BCO1 (beta-carotene oxygenase 1)	protein interactions	53630	3	1	19454	50	ABLIM1
7.691e-03	-4.87	Lrrc7 (leucine rich repeat containing 7)	protein interactions	117284	3	1	19454	50	CAMK2G
7.691e-03	-4.87	Itgb1 (integrin subunit beta 1)	protein interactions	24511	3	1	19454	50	TNC
7.691e-03	-4.87	TULP1 (TUB like protein 1)	protein interactions	7287	3	1	19454	50	NRXN1
7.691e-03	-4.87	Grm5 (glutamate metabotropic receptor 5)	protein interactions	24418	3	1	19454	50	PRKCA
7.746e-03	-4.86	cytoskeleton	cellular component	GO:0005856	2412	13	19108	50	PARD3,ABLIM1,NEBL,DGKG,GFAP,MACF1,KALRN,FMN2,PRKCA,DTNA,CTNNA2,SYNE1,SORBS1
7.782e-03	-4.86	signal transduction	biological process	GO:0007165	4637	21	18204	50	RPS6KA2,RYR3,MACF1,PRKCA,SORBS1,NDRG2,FMN2,ATP1A2,DCLK2,NRG3,RORA,KALRN,CTNND2,ADCY2,NTRK2,PITPNC1,PARD3,DTNA,NTRK3,DGKG,ERBB4
7.809e-03	-4.85	Aldosterone-regulated sodium reabsorption	KEGG pathways	hsa04960	37	2	7161	26	ATP1A2,PRKCA
7.809e-03	-4.85	Aldosterone-regulated sodium reabsorption	KEGG pathways	ko04960	37	2	7161	26	ATP1A2,PRKCA
7.825e-03	-4.85	Glutamatergic synapse	KEGG pathways	ko04724	114	3	7161	26	PRKCA,SLC1A2,ADCY2
7.825e-03	-4.85	Glutamatergic synapse	KEGG pathways	hsa04724	114	3	7161	26	SLC1A2,ADCY2,PRKCA
7.830e-03	-4.85	alphav-beta3 integrin-PKCalpha complex	cellular component	GO:0035866	3	1	19108	50	PRKCA
7.881e-03	-4.84	Syndecan-4-mediated signaling events	Pathway Interaction DB	syndecan_4_pathway	31	2	2226	10	TNC,PRKCA
7.909e-03	-4.84	SNAP91 (synaptosome associated protein 91)	protein interactions	9892	52	2	19454	50	GPM6A,ERBB4
7.928e-03	-4.84	ABLIM1 (actin binding LIM protein 1)	protein interactions	3983	159	3	19454	50	GFAP,NTRK3,NTRK2
7.964e-03	-4.83	Cardiac conduction	REACTOME pathways	R-HSA-5576891	142	3	10285	30	ATP1A2,CAMK2G,RYR3
7.984e-03	-4.83	eye	COSMIC cancer mutations	eye	606	6	16828	49	MACF1,TRPM3,KALRN,NTRK3,CTNND2,ADCY2
8.007e-03	-4.83	modulation of excitatory postsynaptic potential	biological process	GO:0098815	49	2	18204	50	NRXN1,SYNE1
8.021e-03	-4.83	YWHAZ (tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein zeta)	protein interactions	7534	1138	8	19454	50	SORBS1,CAMK2G,MACF1,PARD3,ABLIM1,PRKCA,PITPNC1,NAV2
8.021e-03	-4.83	skin-neck-malignant_melanoma	COSMIC cancer mutations	skin-neck-malignant_melanoma	1223	9	16828	49	ADCY2,GPC5,LRP1B,TNC,ATP1A2,ERBB4,CTNND2,TRPM3,SYNE1
8.078e-03	-4.82	SoHo_dom	interpro domains	IPR003127	3	1	18521	50	SORBS1
8.078e-03	-4.82	SPRY3_RyR	interpro domains	IPR035762	3	1	18521	50	RYR3
8.078e-03	-4.82	Ryanodine_rcpt	interpro domains	IPR003032	3	1	18521	50	RYR3
8.078e-03	-4.82	Nav/unc-53	interpro domains	IPR039041	3	1	18521	50	NAV2
8.078e-03	-4.82	NR_DBD_ROR	interpro domains	IPR044101	3	1	18521	50	RORA
8.078e-03	-4.82	TM_ErbB1	interpro domains	IPR049328	3	1	18521	50	ERBB4
8.078e-03	-4.82	Neuregulin	interpro domains	IPR040180	3	1	18521	50	NRG3
8.078e-03	-4.82	Ryanrecept_TM4-6	interpro domains	IPR009460	3	1	18521	50	RYR3
8.078e-03	-4.82	Ryan_recept	interpro domains	IPR013333	3	1	18521	50	RYR3
8.078e-03	-4.82	AKAP6/CEP68	interpro domains	IPR026696	3	1	18521	50	SYNE1
8.078e-03	-4.82	SPRY1_RyR	interpro domains	IPR035761	3	1	18521	50	RYR3
8.078e-03	-4.82	RYDR_Jsol	interpro domains	IPR048581	3	1	18521	50	RYR3
8.078e-03	-4.82	Protein_kinase_C_a/b/g	interpro domains	IPR014375	3	1	18521	50	PRKCA
8.078e-03	-4.82	Myelin_PLP	interpro domains	IPR001614	3	1	18521	50	GPM6A
8.078e-03	-4.82	SPRY2_RyR	interpro domains	IPR035764	3	1	18521	50	RYR3
8.078e-03	-4.82	Myelin_PLP_CS	interpro domains	IPR018237	3	1	18521	50	GPM6A
8.078e-03	-4.82	Vinculin_CS	interpro domains	IPR000633	3	1	18521	50	CTNNA2
8.078e-03	-4.82	DAG_kinase_typeI_N	interpro domains	IPR029477	3	1	18521	50	DGKG
8.078e-03	-4.82	DGK_typeI_N_sf	interpro domains	IPR038199	3	1	18521	50	DGKG
8.078e-03	-4.82	ROR_rcpt	interpro domains	IPR003079	3	1	18521	50	RORA
8.097e-03	-4.82	regulation of nervous system development	biological process	GO:0051960	456	5	18204	50	MACF1,PARD3,GFAP,NRXN1,NTRK2
8.103e-03	-4.82	alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity	molecular function	GO:0008454	3	1	18094	49	MGAT4C
8.103e-03	-4.82	cysteine transmembrane transporter activity	molecular function	GO:0033229	3	1	18094	49	SLC1A2
8.103e-03	-4.82	epidermal growth factor receptor activity	molecular function	GO:0005006	3	1	18094	49	ERBB4
8.103e-03	-4.82	urea channel activity	molecular function	GO:0015265	3	1	18094	49	SLC14A1
8.103e-03	-4.82	neuregulin receptor activity	molecular function	GO:0038131	3	1	18094	49	ERBB4
8.196e-03	-4.80	PLC beta mediated events	REACTOME pathways	R-HSA-112043	47	2	10285	30	ADCY2,PRKCA
8.206e-03	-4.80	GOLGA6A (golgin A6 family member A)	protein interactions	342096	53	2	19454	50	GFAP,NEBL
8.218e-03	-4.80	meiotic chromosome movement towards spindle pole	biological process	GO:0016344	3	1	18204	50	FMN2
8.218e-03	-4.80	trans-synaptic signaling by BDNF, modulating synaptic transmission	biological process	GO:0099183	3	1	18204	50	NTRK2
8.218e-03	-4.80	formin-nucleated actin cable assembly	biological process	GO:0070649	3	1	18204	50	FMN2
8.218e-03	-4.80	regulation of calcium:sodium antiporter activity	biological process	GO:1903279	3	1	18204	50	ATP1A2
8.218e-03	-4.80	central nervous system morphogenesis	biological process	GO:0021551	3	1	18204	50	ERBB4
8.218e-03	-4.80	regulation of platelet-derived growth factor production	biological process	GO:0090361	3	1	18204	50	NDRG2
8.218e-03	-4.80	regulation of dense core granule biogenesis	biological process	GO:2000705	3	1	18204	50	PRKCA
8.218e-03	-4.80	formin-nucleated actin cable organization	biological process	GO:0110009	3	1	18204	50	FMN2
8.218e-03	-4.80	cysteine transport	biological process	GO:0042883	3	1	18204	50	SLC1A2
8.218e-03	-4.80	bud outgrowth involved in lung branching	biological process	GO:0060447	3	1	18204	50	TNC
8.218e-03	-4.80	Schwann cell proliferation	biological process	GO:0014010	3	1	18204	50	GFAP
8.218e-03	-4.80	cysteine transmembrane transport	biological process	GO:1903712	3	1	18204	50	SLC1A2
8.218e-03	-4.80	positive regulation of Schwann cell proliferation	biological process	GO:0010625	3	1	18204	50	GFAP
8.218e-03	-4.80	radial glia guided migration of Purkinje cell	biological process	GO:0021942	3	1	18204	50	CTNNA2
8.218e-03	-4.80	vagus nerve development	biological process	GO:0021564	3	1	18204	50	NAV2
8.218e-03	-4.80	neuroligin clustering involved in postsynaptic membrane assembly	biological process	GO:0097118	3	1	18204	50	NRXN1
8.218e-03	-4.80	mammary placode formation	biological process	GO:0060596	3	1	18204	50	NRG3
8.218e-03	-4.80	cardiac muscle thin filament assembly	biological process	GO:0071691	3	1	18204	50	NEBL
8.218e-03	-4.80	nuclear matrix anchoring at nuclear membrane	biological process	GO:0090292	3	1	18204	50	SYNE1
8.238e-03	-4.80	RyR	pfam domains	PF02026	3	1	17795	49	RYR3
8.238e-03	-4.80	Myelin_PLP	pfam domains	PF01275	3	1	17795	49	GPM6A
8.238e-03	-4.80	RYDR_Jsol	pfam domains	PF21119	3	1	17795	49	RYR3
8.238e-03	-4.80	RR_TM4-6	pfam domains	PF06459	3	1	17795	49	RYR3
8.238e-03	-4.80	DAG_kinase_N	pfam domains	PF14513	3	1	17795	49	DGKG
8.238e-03	-4.80	SR_plectin_7	pfam domains	PF21097	3	1	17795	49	MACF1
8.238e-03	-4.80	TM_ErbB1	pfam domains	PF21314	3	1	17795	49	ERBB4
8.238e-03	-4.80	Sorb	pfam domains	PF02208	3	1	17795	49	SORBS1
8.317e-03	-4.79	synaptic signaling	biological process	GO:0099536	459	5	18204	50	RPS6KA2,DTNA,NTRK2,SLC1A2,NRXN1
8.327e-03	-4.79	cellular response to nerve growth factor stimulus	biological process	GO:1990090	50	2	18204	50	NTRK3,NTRK2
8.343e-03	-4.79	CCDC57 (coiled-coil domain containing 57)	protein interactions	284001	162	3	19454	50	GFAP,ABLIM1,DCLK2
8.358e-03	-4.78	neck	COSMIC cancer mutations	neck	1231	9	16828	49	ERBB4,CTNND2,TRPM3,SYNE1,TNC,ATP1A2,ADCY2,GPC5,LRP1B
8.373e-03	-4.78	PRKCI (protein kinase C iota)	protein interactions	5584	312	4	19454	50	PRKCA,NTRK3,PARD3,NTRK2
8.537e-03	-4.76	G alpha (z) signalling events	REACTOME pathways	R-HSA-418597	48	2	10285	30	PRKCA,ADCY2
8.537e-03	-4.76	G-protein mediated events	REACTOME pathways	R-HSA-112040	48	2	10285	30	ADCY2,PRKCA
8.603e-03	-4.76	central_nervous_system-temporoparietal-glioma-astrocytoma_Grade_IV	COSMIC cancer mutations	central_nervous_system-temporoparietal-glioma-astrocytoma_Grade_IV	48	2	16828	49	RYR3,PARD3
8.613e-03	-4.75	thyroid-carcinoma	COSMIC cancer mutations	thyroid-carcinoma	4126	20	16828	49	GPC5,DTNA,LRP1B,ADCY2,RYR3,NTRK3,DGKG,LSAMP,TRPM3,NRXN1,GLIS3,ERBB4,SOX5,MACF1,NAV2,ATP1A2,PARD3,SYNE1,PSD2,CTNND2
8.617e-03	-4.75	regulation of membrane potential	biological process	GO:0042391	463	5	18204	50	SYNE1,ATP1A2,NRXN1,SLC4A4,NTRK2
8.627e-03	-4.75	LRBA (LPS responsive beige-like anchor protein)	protein interactions	987	164	3	19454	50	MACF1,NTRK3,NTRK2
8.658e-03	-4.75	S_TKc	smart domains	SM00220	348	5	9717	36	KALRN,DCLK2,PRKCA,RPS6KA2,CAMK2G
8.667e-03	-4.75	anchoring junction	cellular component	GO:0070161	902	7	19108	50	TNC,CDH20,PARD3,CTNNA2,ATP1A2,CTNND2,SORBS1
8.702e-03	-4.74	learning	biological process	GO:0007612	154	3	18204	50	ATP1A2,NRXN1,NTRK2
8.748e-03	-4.74	ZYX (zyxin)	protein interactions	7791	316	4	19454	50	SORBS1,MACF1,NEBL,ABLIM1
8.771e-03	-4.74	positive regulation of nervous system development	biological process	GO:0051962	296	4	18204	50	MACF1,NTRK2,GFAP,NRXN1
8.814e-03	-4.73	PLCB1 (phospholipase C beta 1)	protein interactions	23236	55	2	19454	50	PRKCA,PARD3
8.814e-03	-4.73	SYN1 (synapsin I)	protein interactions	6853	55	2	19454	50	GPM6A,CAMK2G
8.836e-03	-4.73	skin-back-malignant_melanoma	COSMIC cancer mutations	skin-back-malignant_melanoma	280	4	16828	49	ERBB4,SYNE1,LRP1B,ATP1A2
8.841e-03	-4.73	neuronal cell body	cellular component	GO:0043025	489	5	19108	50	PSD2,GPM6A,ATP1A2,NRXN1,CTNND2
8.857e-03	-4.73	regeneration	biological process	GO:0031099	155	3	18204	50	ERBB4,TNC,GFAP
8.869e-03	-4.73	mannosyl-glycoprotein N-acetylglucosaminyltransferases	BIOCYC pathways	META_PWY-7426	8	1	902	1	MGAT4C
8.873e-03	-4.72	carboxylic acid transport	biological process	GO:0046942	297	4	18204	50	GFAP,SFXN5,SLC1A2,NTRK2
8.917e-03	-4.72	SCLT1 (sodium channel and clathrin linker 1)	protein interactions	132320	166	3	19454	50	ATP1A2,NEBL,ABLIM1
8.972e-03	-4.71	sodium ion transmembrane transporter activity	molecular function	GO:0015081	158	3	18094	49	SLC4A4,SLC1A2,ATP1A2
8.972e-03	-4.71	integrin binding	molecular function	GO:0005178	158	3	18094	49	PRKCA,TNC,GFAP
8.976e-03	-4.71	organic acid transport	biological process	GO:0015849	298	4	18204	50	GFAP,NTRK2,SLC1A2,SFXN5
8.982e-03	-4.71	response to nerve growth factor	biological process	GO:1990089	52	2	18204	50	NTRK3,NTRK2
9.008e-03	-4.71	Oocyte meiosis	KEGG pathways	ko04114	120	3	7161	26	CAMK2G,RPS6KA2,ADCY2
9.008e-03	-4.71	Oocyte meiosis	KEGG pathways	hsa04114	120	3	7161	26	ADCY2,CAMK2G,RPS6KA2
9.053e-03	-4.70	CTNNB1 (catenin beta 1)	protein interactions	1499	926	7	19454	50	DTNA,CTNND2,PRKCA,NTRK3,CTNNA2,SORBS1,PARD3
9.125e-03	-4.70	L1CAM (L1 cell adhesion molecule)	protein interactions	3897	56	2	19454	50	RPS6KA2,GPM6A
9.156e-03	-4.69	ear	COSMIC cancer mutations	ear	624	6	16828	49	RPS6KA2,MGAT4C,LRP1B,NPAS3,SLC14A1,TNC
9.171e-03	-4.69	positive regulation of synaptic transmission	biological process	GO:0050806	157	3	18204	50	NTRK2,NRXN1,GFAP
9.212e-03	-4.69	GAB1 (GRB2 associated binding protein 1)	protein interactions	2549	168	3	19454	50	NTRK3,PARD3,NTRK2
9.231e-03	-4.69	ACTA1 (actin alpha 1, skeletal muscle)	protein interactions	58	321	4	19454	50	DTNA,MACF1,PRKCA,SORBS1
9.295e-03	-4.68	MAPRE1 (microtubule associated protein RP/EB family member 1)	protein interactions	22919	504	5	19454	50	NAV2,CAMK2G,MACF1,PRKCA,ABLIM1
9.301e-03	-4.68	-	gene3d domains	1.10.490.160	3	1	14470	45	RYR3
9.301e-03	-4.68	-	gene3d domains	6.10.250.2510	3	1	14470	45	CTNNA2
9.301e-03	-4.68	Diacylglycerol kinase alpha	gene3d domains	1.10.238.110	3	1	14470	45	DGKG
9.337e-03	-4.67	transmembrane transporter activity	molecular function	GO:0022857	1110	8	18094	49	SLC1A2,ATP1A2,RYR3,SLC4A4,SFXN5,GPM6A,SLC14A1,TRPM3
9.346e-03	-4.67	LRRNT	interpro domains	IPR000372	54	2	18521	50	NTRK2,NTRK3
9.361e-03	-4.67	PIAS2 (protein inhibitor of activated STAT 2)	protein interactions	9063	169	3	19454	50	SOX5,NAV2,GFAP
9.401e-03	-4.67	postsynaptic density	cellular component	GO:0014069	317	4	19108	50	ERBB4,KALRN,CTNND2,NTRK2
9.442e-03	-4.66	NXPH3 (neurexophilin 3)	protein interactions	11248	57	2	19454	50	CTNNA2,NRXN1
9.520e-03	-4.65	MAPK family signaling cascades	REACTOME pathways	R-HSA-5683057	290	4	10285	30	CAMK2G,ERBB4,KALRN,NRG3
9.616e-03	-4.64	lung-carcinoma-squamous_cell_carcinoma	COSMIC cancer mutations	lung-carcinoma-squamous_cell_carcinoma	14664	48	16828	49	NPAS3,LSAMP,CDH20,CTNND2,TNC,NTRK2,SOX5,TRPM3,GFAP,NTRK3,RFX4,NEBL,SLC1A2,SORBS1,MACF1,GPM6A,NAV2,RORA,ABLIM1,HPSE2,ERBB4,NRXN1,SLC4A4,GPC5,LRP1B,ADCY2,PSD2,ATP1A2,CAMK2G,NRG3,SFXN5,GLIS3,NKAIN3,RPS6KA2,DGKG,FMN2,NTM,PRKCA,RYR3,DTNA,SYNE1,MSI2,PARD3,SLC14A1,DCLK2,KALRN,MGAT4C,PITPNC1
9.665e-03	-4.64	PPFIBP1 (PPFIA binding protein 1)	protein interactions	8496	171	3	19454	50	RPS6KA2,NTRK2,PARD3
9.682e-03	-4.64	AGC-kinase_C	interpro domains	IPR000961	55	2	18521	50	RPS6KA2,PRKCA
9.703e-03	-4.64	C1_1	pfam domains	PF00130	54	2	17795	49	PRKCA,DGKG
9.714e-03	-4.63	cell motility	biological process	GO:0048870	1101	8	18204	50	CTNNA2,NTRK2,CDH20,NRG3,GPM6A,FMN2,ERBB4,GPC5
9.763e-03	-4.63	GRIN2B (glutamate ionotropic receptor NMDA type subunit 2B)	protein interactions	2904	58	2	19454	50	CAMK2G,PRKCA
9.763e-03	-4.63	SNAP25 (synaptosome associated protein 25)	protein interactions	6616	58	2	19454	50	GPM6A,PRKCA
9.763e-03	-4.63	CILK1 (ciliogenesis associated kinase 1)	protein interactions	22858	58	2	19454	50	CAMK2G,MSI2
9.770e-03	-4.63	regulation of response to stimulus	biological process	GO:0048583	4104	19	18204	50	MACF1,SORBS1,PRKCA,NDRG2,FMN2,KALRN,NRXN1,RORA,GPC5,TNC,SYNE1,CTNNA2,PSD2,CTNND2,NTRK2,NTRK3,DGKG,CAMK2G,ERBB4
9.774e-03	-4.63	nucleotide binding	molecular function	GO:0000166	2128	12	18094	49	NAV2,ATP1A2,CAMK2G,NTRK3,NTRK2,RPS6KA2,DCLK2,DGKG,ERBB4,KALRN,PRKCA,ADCY2
9.810e-03	-4.62	nucleoside phosphate binding	molecular function	GO:1901265	2129	12	18094	49	ATP1A2,NAV2,DGKG,DCLK2,RPS6KA2,NTRK3,NTRK2,CAMK2G,KALRN,PRKCA,ERBB4,ADCY2
9.833e-03	-4.62	APC (APC regulator of WNT signaling pathway)	protein interactions	324	327	4	19454	50	PARD3,NAV2,SYNE1,MACF1
9.833e-03	-4.62	ROR2 (receptor tyrosine kinase like orphan receptor 2)	protein interactions	4920	327	4	19454	50	RPS6KA2,DTNA,SORBS1,PARD3
9.942e-03	-4.61	EF-hand	gene3d domains	1.10.238.10	272	4	14470	45	DGKG,RYR3,DTNA,MACF1
9.975e-03	-4.61	LSR (lipolysis stimulated lipoprotein receptor)	protein interactions	51599	173	3	19454	50	NTRK2,PARD3,NTRK3
9.984e-03	-4.61	Developmental Biology	REACTOME pathways	R-HSA-1266738	1075	8	10285	30	NRG3,ABLIM1,ERBB4,KALRN,RPS6KA2,CTNNA2,PRKCA,CAMK2G
1.006e-02	-4.60	MYELIN_PLP_1	prosite domains	PS00575	3	1	12186	41	GPM6A
1.006e-02	-4.60	MYELIN_PLP_2	prosite domains	PS01004	3	1	12186	41	GPM6A
1.006e-02	-4.60	SOHO	prosite domains	PS50831	3	1	12186	41	SORBS1
1.006e-02	-4.60	VINCULIN_1	prosite domains	PS00663	3	1	12186	41	CTNNA2
1.009e-02	-4.60	HTATIP2 (HIV-1 Tat interactive protein 2)	protein interactions	10553	59	2	19454	50	PRKCA,PITPNC1
1.009e-02	-4.60	ADAM17 (ADAM metallopeptidase domain 17)	protein interactions	6868	59	2	19454	50	ERBB4,CAMK2G
1.013e-02	-4.59	CDCA3 (cell division cycle associated 3)	protein interactions	83461	174	3	19454	50	RPS6KA2,NTRK3,NTRK2
1.013e-02	-4.59	APPL1 (adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 1)	protein interactions	26060	174	3	19454	50	NTRK2,NTRK3,DTNA
1.024e-02	-4.58	IGKV@ (immunoglobulin kappa variable cluster)	protein interactions	3519	4	1	19454	50	LRP1B
1.024e-02	-4.58	Pick1 (protein interacting with PRKCA 1)	protein interactions	84591	4	1	19454	50	PRKCA
1.024e-02	-4.58	AVPR1A (arginine vasopressin receptor 1A)	protein interactions	552	4	1	19454	50	PRKCA
1.024e-02	-4.58	CALML4 (calmodulin like 4)	protein interactions	91860	4	1	19454	50	CAMK2G
1.024e-02	-4.58	CCDC126 (coiled-coil domain containing 126)	protein interactions	90693	4	1	19454	50	GPM6A
1.024e-02	-4.58	Nme2 (NME/NM23 nucleoside diphosphate kinase 2)	protein interactions	18103	4	1	19454	50	RORA
1.024e-02	-4.58	Ngfr (nerve growth factor receptor)	protein interactions	24596	4	1	19454	50	NTRK3
1.024e-02	-4.58	Dnaja1 (DnaJ heat shock protein family (Hsp40) member A1)	protein interactions	15502	4	1	19454	50	GLIS3
1.029e-02	-4.58	PPP1R9B (protein phosphatase 1 regulatory subunit 9B)	protein interactions	84687	175	3	19454	50	DCLK2,NAV2,RPS6KA2
1.030e-02	-4.58	RORNUCRECPTR	prints domains	PR01293	3	1	5227	18	RORA
1.030e-02	-4.58	RYANODINER	prints domains	PR00795	3	1	5227	18	RYR3
1.030e-02	-4.58	MYELINPLP	prints domains	PR00214	3	1	5227	18	GPM6A
1.040e-02	-4.57	export from cell	biological process	GO:0140352	485	5	18204	50	NTRK2,CAMK2G,NRXN1,SLC4A4,ATP1A2
1.042e-02	-4.56	F11R (F11 receptor)	protein interactions	50848	60	2	19454	50	PRKCA,PARD3
1.043e-02	-4.56	internode region of axon	cellular component	GO:0033269	4	1	19108	50	PARD3
1.043e-02	-4.56	tenascin complex	cellular component	GO:0090733	4	1	19108	50	TNC
1.049e-02	-4.56	import across plasma membrane	biological process	GO:0098739	165	3	18204	50	ATP1A2,GFAP,SLC1A2
1.071e-02	-4.54	Heparan sulfate/heparin (HS-GAG) metabolism	REACTOME pathways	R-HSA-1638091	54	2	10285	30	HPSE2,GPC5
1.072e-02	-4.54	visual behavior	biological process	GO:0007632	57	2	18204	50	ATP1A2,SLC1A2
1.076e-02	-4.53	AbLIM_anchor	interpro domains	IPR032402	4	1	18521	50	ABLIM1
1.076e-02	-4.53	TRPM_tetra	interpro domains	IPR032415	4	1	18521	50	TRPM3
1.076e-02	-4.53	RSK_N	interpro domains	IPR041906	4	1	18521	50	RPS6KA2
1.076e-02	-4.53	Tyr_kinase_EGF/ERB/XmrK_rcpt	interpro domains	IPR016245	4	1	18521	50	ERBB4
1.076e-02	-4.53	TRPM_tetra_sf	interpro domains	IPR037162	4	1	18521	50	TRPM3
1.076e-02	-4.53	KASH	interpro domains	IPR012315	4	1	18521	50	SYNE1
1.076e-02	-4.53	NDRG	interpro domains	IPR004142	4	1	18521	50	NDRG2
1.076e-02	-4.53	Alpha_catenin	interpro domains	IPR001033	4	1	18521	50	CTNNA2
1.076e-02	-4.53	Na/K-Atpase_Interacting	interpro domains	IPR008516	4	1	18521	50	NKAIN3
1.076e-02	-4.53	Desmoplakin_Spectrin-like	interpro domains	IPR041573	4	1	18521	50	MACF1
1.076e-02	-4.53	Glyco_transf_54	interpro domains	IPR006759	4	1	18521	50	MGAT4C
1.076e-02	-4.53	Nebulin_repeat	interpro domains	IPR000900	4	1	18521	50	NEBL
1.076e-02	-4.53	Ca/CaM-dep_prot_kinase-assoc	interpro domains	IPR013543	4	1	18521	50	CAMK2G
1.076e-02	-4.53	PCN-like_spectrin-like_rpt	interpro domains	IPR049538	4	1	18521	50	MACF1
1.077e-02	-4.53	KIDINS220 (kinase D interacting substrate 220)	protein interactions	57498	178	3	19454	50	NTRK3,PARD3,NTRK2
1.079e-02	-4.53	citrate transmembrane transporter activity	molecular function	GO:0015137	4	1	18094	49	SFXN5
1.079e-02	-4.53	ryanodine-sensitive calcium-release channel activity	molecular function	GO:0005219	4	1	18094	49	RYR3
1.079e-02	-4.53	tricarboxylic acid transmembrane transporter activity	molecular function	GO:0015142	4	1	18094	49	SFXN5
1.079e-02	-4.53	brain-derived neurotrophic factor binding	molecular function	GO:0048403	4	1	18094	49	NTRK2
1.094e-02	-4.52	regulation of amino acid uptake involved in synaptic transmission	biological process	GO:0051941	4	1	18204	50	ATP1A2
1.094e-02	-4.52	response to glycoside	biological process	GO:1903416	4	1	18204	50	ATP1A2
1.094e-02	-4.52	trans-synaptic signaling by BDNF	biological process	GO:0099191	4	1	18204	50	NTRK2
1.094e-02	-4.52	regulation of angiotensin-activated signaling pathway	biological process	GO:0110061	4	1	18204	50	PRKCA
1.094e-02	-4.52	regulation of glutamate uptake involved in transmission of nerve impulse	biological process	GO:0051946	4	1	18204	50	ATP1A2
1.094e-02	-4.52	positive regulation of mesenchymal stem cell differentiation	biological process	GO:2000741	4	1	18204	50	SOX5
1.094e-02	-4.52	regulation of mini excitatory postsynaptic potential	biological process	GO:0061884	4	1	18204	50	SYNE1
1.094e-02	-4.52	cardiac muscle tissue regeneration	biological process	GO:0061026	4	1	18204	50	ERBB4
1.094e-02	-4.52	nuclear matrix organization	biological process	GO:0043578	4	1	18204	50	SYNE1
1.094e-02	-4.52	desmosome assembly	biological process	GO:0002159	4	1	18204	50	PRKCA
1.094e-02	-4.52	brain-derived neurotrophic factor receptor signaling pathway	biological process	GO:0031547	4	1	18204	50	NTRK2
1.094e-02	-4.52	negative regulation of protein kinase C signaling	biological process	GO:0090038	4	1	18204	50	DGKG
1.094e-02	-4.52	regulation of systemic arterial blood pressure by baroreceptor feedback	biological process	GO:0003025	4	1	18204	50	NAV2
1.097e-02	-4.51	TRPM_tetra	pfam domains	PF16519	4	1	17795	49	TRPM3
1.097e-02	-4.51	AbLIM_anchor	pfam domains	PF16182	4	1	17795	49	ABLIM1
1.097e-02	-4.51	NKAIN	pfam domains	PF05640	4	1	17795	49	NKAIN3
1.097e-02	-4.51	Glyco_transf_54	pfam domains	PF04666	4	1	17795	49	MGAT4C
1.097e-02	-4.51	Spectrin_4	pfam domains	PF21020	4	1	17795	49	MACF1
1.097e-02	-4.51	Spectrin_3	pfam domains	PF21019	4	1	17795	49	MACF1
1.097e-02	-4.51	Nebulin	pfam domains	PF00880	4	1	17795	49	NEBL
1.097e-02	-4.51	CaMKII_AD	pfam domains	PF08332	4	1	17795	49	CAMK2G
1.097e-02	-4.51	Ndr	pfam domains	PF03096	4	1	17795	49	NDRG2
1.097e-02	-4.51	KASH	pfam domains	PF10541	4	1	17795	49	SYNE1
1.097e-02	-4.51	Spectrin_2	pfam domains	PF18373	4	1	17795	49	MACF1
1.098e-02	-4.51	primitive_neuroectodermal_tumour-medulloblastoma	COSMIC cancer mutations	primitive_neuroectodermal_tumour-medulloblastoma	15350	49	16828	49	TRPM3,GFAP,RFX4,NEBL,NTRK3,SLC1A2,SORBS1,HPSE2,ABLIM1,RORA,MACF1,GPM6A,NAV2,LSAMP,NPAS3,CDH20,TNC,CTNND2,SOX5,NTRK2,NKAIN3,SFXN5,GLIS3,NRG3,DTNA,NTM,PRKCA,RYR3,RPS6KA2,DGKG,FMN2,SLC14A1,PARD3,MSI2,SYNE1,PITPNC1,MGAT4C,KALRN,DCLK2,NRXN1,SLC4A4,ERBB4,NDRG2,LRP1B,GPC5,ADCY2,ATP1A2,PSD2,CAMK2G
1.107e-02	-4.50	Sorb	smart domains	SM00459	3	1	9717	36	SORBS1
1.107e-02	-4.50	PLP	smart domains	SM00002	3	1	9717	36	GPM6A
1.110e-02	-4.50	ARHGAP29 (Rho GTPase activating protein 29)	protein interactions	9411	62	2	19454	50	PARD3,CAMK2G
1.110e-02	-4.50	PTPN13 (protein tyrosine phosphatase non-receptor type 13)	protein interactions	5783	180	3	19454	50	NTRK3,PARD3,NTRK2
1.111e-02	-4.50	asymmetric synapse	cellular component	GO:0032279	333	4	19108	50	KALRN,CTNND2,NTRK2,ERBB4
1.118e-02	-4.49	parathyroid-carcinoma	COSMIC cancer mutations	parathyroid-carcinoma	300	4	16828	49	RYR3,SYNE1,MACF1,GPC5
1.134e-02	-4.48	IGc2	smart domains	SM00408	239	4	9717	36	NTM,LSAMP,NTRK2,KALRN
1.138e-02	-4.48	head_neck	COSMIC cancer mutations	head_neck	15361	49	16828	49	SOX5,NTRK2,CTNND2,TNC,CDH20,NPAS3,LSAMP,RORA,NAV2,GPM6A,MACF1,HPSE2,ABLIM1,SORBS1,SLC1A2,NTRK3,NEBL,RFX4,GFAP,TRPM3,CAMK2G,PSD2,ATP1A2,NDRG2,ADCY2,LRP1B,GPC5,SLC4A4,NRXN1,ERBB4,KALRN,DCLK2,PITPNC1,MGAT4C,SYNE1,PARD3,SLC14A1,MSI2,RYR3,PRKCA,NTM,DGKG,FMN2,RPS6KA2,DTNA,GLIS3,SFXN5,NRG3,NKAIN3
1.143e-02	-4.47	human chr14q13.1	chromosome location	human chr14q13.1	6	1	26134	50	NPAS3
1.143e-02	-4.47	human chr4q34.2	chromosome location	human chr4q34.2	6	1	26134	50	GPM6A
1.144e-02	-4.47	PRPH (peripherin)	protein interactions	5630	182	3	19454	50	GFAP,SORBS1,ABLIM1
1.144e-02	-4.47	PAG1 (phosphoprotein membrane anchor with glycosphingolipid microdomains 1)	protein interactions	55824	63	2	19454	50	NTRK3,GFAP
1.144e-02	-4.47	DCAF16 (DDB1 and CUL4 associated factor 16)	protein interactions	54876	63	2	19454	50	DGKG,PSD2
1.145e-02	-4.47	protein localization to synapse	biological process	GO:0035418	59	2	18204	50	NRXN1,ERBB4
1.148e-02	-4.47	adrenal_cortical_adenoma	COSMIC cancer mutations	adrenal_cortical_adenoma	161	3	16828	49	ADCY2,LRP1B,FMN2
1.162e-02	-4.46	Neurotransmitter uptake and Metabolism In Glial Cells	REACTOME pathways	R-HSA-112313	4	1	10285	30	SLC1A2
1.162e-02	-4.46	Astrocytic Glutamate-Glutamine Uptake And Metabolism	REACTOME pathways	R-HSA-210455	4	1	10285	30	SLC1A2
1.165e-02	-4.45	leading edge membrane	cellular component	GO:0031256	180	3	19108	50	PSD2,MACF1,SLC1A2
1.167e-02	-4.45	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-peripheral_T_cell_lymphoma_unspecified	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-peripheral_T_cell_lymphoma_unspecified	162	3	16828	49	MACF1,SYNE1,RYR3
1.171e-02	-4.45	organic substance transport	biological process	GO:0071702	1881	11	18204	50	FMN2,MACF1,SLC4A4,GFAP,CAMK2G,LRP1B,SLC14A1,SFXN5,SLC1A2,NTRK2,PITPNC1
1.179e-02	-4.44	SYNC (syncoilin, intermediate filament protein)	protein interactions	81493	64	2	19454	50	DTNA,GFAP
1.181e-02	-4.44	C1-like_sf	interpro domains	IPR046349	61	2	18521	50	PRKCA,DGKG
1.182e-02	-4.44	regulation of glucose import	biological process	GO:0046324	60	2	18204	50	SLC1A2,SORBS1
1.182e-02	-4.44	export across plasma membrane	biological process	GO:0140115	60	2	18204	50	SLC4A4,ATP1A2
1.182e-02	-4.44	transmission of nerve impulse	biological process	GO:0019226	60	2	18204	50	NTRK2,ATP1A2
1.191e-02	-4.43	SLC3A2 (solute carrier family 3 member 2)	protein interactions	6520	346	4	19454	50	PARD3,NTRK3,SLC1A2,RPS6KA2
1.195e-02	-4.43	ENTR1 (endosome associated trafficking regulator 1)	protein interactions	10807	185	3	19454	50	PARD3,RPS6KA2,GFAP
1.202e-02	-4.42	PTPN11 (protein tyrosine phosphatase non-receptor type 11)	protein interactions	5781	347	4	19454	50	NTRK2,NTRK3,ERBB4,PRKCA
1.204e-02	-4.42	protein phosphorylation	biological process	GO:0006468	503	5	18204	50	RPS6KA2,ERBB4,NTRK2,PRKCA,KALRN
1.205e-02	-4.42	TRIM67 (tripartite motif containing 67)	protein interactions	440730	4804	20	19454	50	SLC4A4,KALRN,GFAP,TNC,PARD3,CAMK2G,MACF1,CTNNA2,GPM6A,LSAMP,DCLK2,MSI2,PRKCA,CTNND2,PITPNC1,RPS6KA2,DTNA,SYNE1,ATP1A2,NTM
1.209e-02	-4.42	kidney	COSMIC cancer mutations	kidney	15380	49	16828	49	CAMK2G,ATP1A2,PSD2,NDRG2,GPC5,LRP1B,ADCY2,NRXN1,SLC4A4,ERBB4,PITPNC1,MGAT4C,KALRN,DCLK2,PARD3,SLC14A1,MSI2,SYNE1,DTNA,NTM,PRKCA,RYR3,RPS6KA2,DGKG,FMN2,NKAIN3,SFXN5,GLIS3,NRG3,SOX5,NTRK2,TNC,CTNND2,CDH20,LSAMP,NPAS3,HPSE2,ABLIM1,RORA,MACF1,NAV2,GPM6A,SLC1A2,SORBS1,RFX4,NEBL,NTRK3,TRPM3,GFAP
1.216e-02	-4.41	parathyroid	COSMIC cancer mutations	parathyroid	476	5	16828	49	GPC5,RYR3,SYNE1,GPM6A,MACF1
1.220e-02	-4.41	regulation of vascular endothelial growth factor production	biological process	GO:0010574	61	2	18204	50	NDRG2,RORA
1.229e-02	-4.40	Ion transport by P-type ATPases	REACTOME pathways	R-HSA-936837	58	2	10285	30	ATP1A2,CAMK2G
1.238e-02	-4.39	EPHA2 (EPH receptor A2)	protein interactions	1969	350	4	19454	50	RPS6KA2,NTRK2,NTRK3,PARD3
1.238e-02	-4.39	TRPM, tetramerisation domain	gene3d domains	1.20.5.1010	4	1	14470	45	TRPM3
1.238e-02	-4.39	-	gene3d domains	1.20.58.1060	4	1	14470	45	MACF1
1.240e-02	-4.39	Endocrine and other factor-regulated calcium reabsorption	KEGG pathways	hsa04961	47	2	7161	26	PRKCA,ATP1A2
1.240e-02	-4.39	Endocrine and other factor-regulated calcium reabsorption	KEGG pathways	ko04961	47	2	7161	26	ATP1A2,PRKCA
1.248e-02	-4.38	SNAP23 (synaptosome associated protein 23)	protein interactions	8773	188	3	19454	50	PRKCA,RPS6KA2,PARD3
1.249e-02	-4.38	central nervous system neuron differentiation	biological process	GO:0021953	176	3	18204	50	NTRK2,RORA,DCLK2
1.249e-02	-4.38	back	COSMIC cancer mutations	back	310	4	16828	49	LRP1B,ATP1A2,ERBB4,SYNE1
1.253e-02	-4.38	postsynaptic specialization	cellular component	GO:0099572	345	4	19108	50	ERBB4,CTNND2,NTRK2,KALRN
1.262e-02	-4.37	Ig-like_fold	interpro domains	IPR013783	721	6	18521	50	LSAMP,NTRK3,NTRK2,NTM,KALRN,TNC
1.266e-02	-4.37	peripheral_T_cell_lymphoma_unspecified	COSMIC cancer mutations	peripheral_T_cell_lymphoma_unspecified	167	3	16828	49	RYR3,SYNE1,MACF1
1.271e-02	-4.37	cadherin binding	molecular function	GO:0045296	335	4	18094	49	CDH20,CTNNA2,CTNND2,MACF1
1.279e-02	-4.36	SUI2 (translation initiation factor eIF2 subunit alpha)	protein interactions	853463	5	1	19454	50	PRKCA
1.279e-02	-4.36	RFX4 (regulatory factor X4)	protein interactions	5992	5	1	19454	50	RFX4
1.279e-02	-4.36	RVS161 (amphiphysin-like protein RVS161)	protein interactions	850367	5	1	19454	50	GFAP
1.279e-02	-4.36	SYT13 (synaptotagmin 13)	protein interactions	57586	5	1	19454	50	NRXN1
1.279e-02	-4.36	CAMK2N2 (calcium/calmodulin dependent protein kinase II inhibitor 2)	protein interactions	94032	5	1	19454	50	CAMK2G
1.279e-02	-4.36	TRPM6 (transient receptor potential cation channel subfamily M member 6)	protein interactions	140803	5	1	19454	50	TRPM3
1.279e-02	-4.36	GABRR2 (gamma-aminobutyric acid type A receptor subunit rho2)	protein interactions	2570	5	1	19454	50	PRKCA
1.279e-02	-4.36	SLC10A3 (solute carrier family 10 member 3)	protein interactions	8273	5	1	19454	50	SORBS1
1.279e-02	-4.36	Wwp2 (WW domain containing E3 ubiquitin protein ligase 2)	protein interactions	66894	5	1	19454	50	GLIS3
1.279e-02	-4.36	NRG2 (neuregulin 2)	protein interactions	9542	5	1	19454	50	ERBB4
1.279e-02	-4.36	CFHR3 (complement factor H related 3)	protein interactions	10878	5	1	19454	50	PRKCA
1.279e-02	-4.36	DLX3 (distal-less homeobox 3)	protein interactions	1747	5	1	19454	50	PRKCA
1.287e-02	-4.35	PARD6A (par-6 family cell polarity regulator alpha)	protein interactions	50855	67	2	19454	50	PRKCA,PARD3
1.287e-02	-4.35	SHC3 (SHC adaptor protein 3)	protein interactions	53358	67	2	19454	50	NTRK2,ERBB4
1.300e-02	-4.34	functioning	COSMIC cancer mutations	functioning	1803	11	16828	49	SYNE1,SLC1A2,SOX5,NTRK2,HPSE2,TRPM3,NRG3,NTRK3,DGKG,FMN2,RFX4
1.300e-02	-4.34	adrenal_gland-adrenal_gland-adrenal_cortical_carcinoma-functioning	COSMIC cancer mutations	adrenal_gland-adrenal_gland-adrenal_cortical_carcinoma-functioning	1803	11	16828	49	NTRK3,SOX5,FMN2,DGKG,NTRK2,HPSE2,RFX4,TRPM3,SYNE1,SLC1A2,NRG3
1.302e-02	-4.34	calcium- and calmodulin-dependent protein kinase complex	cellular component	GO:0005954	5	1	19108	50	CAMK2G
1.302e-02	-4.34	pancreas-carcinoma	COSMIC cancer mutations	pancreas-carcinoma	14770	48	16828	49	SYNE1,SLC14A1,PARD3,MSI2,KALRN,DCLK2,PITPNC1,MGAT4C,SFXN5,GLIS3,NRG3,NKAIN3,NTM,PRKCA,RYR3,RPS6KA2,DGKG,FMN2,PSD2,ATP1A2,CAMK2G,NRXN1,SLC4A4,ERBB4,NDRG2,LRP1B,GPC5,ADCY2,SLC1A2,SORBS1,RORA,MACF1,NAV2,GPM6A,HPSE2,ABLIM1,TRPM3,GFAP,NTRK3,RFX4,NEBL,CTNND2,TNC,SOX5,NTRK2,NPAS3,LSAMP,CDH20
1.304e-02	-4.34	SH3_9	pfam domains	PF14604	63	2	17795	49	NEBL,SORBS1
1.313e-02	-4.33	response to endogenous stimulus	biological process	GO:0009719	1402	9	18204	50	SOX5,ERBB4,TNC,NTRK3,ATP1A2,SORBS1,NTRK2,SLC1A2,RYR3
1.313e-02	-4.33	central_nervous_system-medulla-primitive_neuroectodermal_tumour-medulloblastoma-desmoplastic	COSMIC cancer mutations	central_nervous_system-medulla-primitive_neuroectodermal_tumour-medulloblastoma-desmoplastic	14773	48	16828	49	GFAP,TRPM3,NEBL,RFX4,NTRK3,SORBS1,SLC1A2,ABLIM1,HPSE2,GPM6A,NAV2,MACF1,RORA,LSAMP,NPAS3,CDH20,TNC,CTNND2,NTRK2,SOX5,NRG3,GLIS3,SFXN5,DTNA,FMN2,DGKG,RPS6KA2,RYR3,PRKCA,NTM,MSI2,PARD3,SLC14A1,SYNE1,MGAT4C,PITPNC1,DCLK2,KALRN,ERBB4,SLC4A4,NRXN1,ADCY2,LRP1B,GPC5,NDRG2,ATP1A2,PSD2,CAMK2G
1.313e-02	-4.33	central_nervous_system-medulla-primitive_neuroectodermal_tumour-medulloblastoma-classic	COSMIC cancer mutations	central_nervous_system-medulla-primitive_neuroectodermal_tumour-medulloblastoma-classic	14773	48	16828	49	NTRK3,NEBL,RFX4,GFAP,TRPM3,RORA,GPM6A,NAV2,MACF1,HPSE2,ABLIM1,SORBS1,SLC1A2,CDH20,NPAS3,LSAMP,SOX5,NTRK2,CTNND2,TNC,RYR3,PRKCA,NTM,DGKG,FMN2,RPS6KA2,DTNA,GLIS3,SFXN5,NRG3,KALRN,DCLK2,PITPNC1,MGAT4C,SYNE1,PARD3,SLC14A1,MSI2,NDRG2,ADCY2,LRP1B,GPC5,SLC4A4,NRXN1,ERBB4,CAMK2G,PSD2,ATP1A2
1.313e-02	-4.33	central_nervous_system-medulla-primitive_neuroectodermal_tumour-medulloblastoma-large_cell	COSMIC cancer mutations	central_nervous_system-medulla-primitive_neuroectodermal_tumour-medulloblastoma-large_cell	14773	48	16828	49	TNC,CTNND2,NTRK2,SOX5,LSAMP,NPAS3,CDH20,SORBS1,SLC1A2,ABLIM1,HPSE2,NAV2,GPM6A,MACF1,RORA,GFAP,TRPM3,NEBL,RFX4,NTRK3,ATP1A2,PSD2,CAMK2G,ERBB4,SLC4A4,NRXN1,ADCY2,LRP1B,GPC5,NDRG2,MSI2,SLC14A1,PARD3,SYNE1,MGAT4C,PITPNC1,DCLK2,KALRN,NRG3,GLIS3,SFXN5,DTNA,FMN2,DGKG,RPS6KA2,RYR3,NTM,PRKCA
1.313e-02	-4.33	central_nervous_system-medulla-primitive_neuroectodermal_tumour-medulloblastoma	COSMIC cancer mutations	central_nervous_system-medulla-primitive_neuroectodermal_tumour-medulloblastoma	14773	48	16828	49	DCLK2,KALRN,MGAT4C,PITPNC1,SYNE1,MSI2,SLC14A1,PARD3,DGKG,FMN2,RPS6KA2,RYR3,PRKCA,NTM,DTNA,NRG3,GLIS3,SFXN5,CAMK2G,PSD2,ATP1A2,ADCY2,LRP1B,GPC5,NDRG2,ERBB4,SLC4A4,NRXN1,GPM6A,NAV2,MACF1,RORA,ABLIM1,HPSE2,SORBS1,SLC1A2,NTRK3,NEBL,RFX4,GFAP,TRPM3,NTRK2,SOX5,CTNND2,TNC,CDH20,NPAS3,LSAMP
1.317e-02	-4.33	classic	COSMIC cancer mutations	classic	14774	48	16828	49	SFXN5,GLIS3,NRG3,NTM,PRKCA,RYR3,RPS6KA2,DGKG,FMN2,DTNA,SYNE1,SLC14A1,PARD3,MSI2,KALRN,DCLK2,PITPNC1,MGAT4C,NRXN1,SLC4A4,ERBB4,NDRG2,LRP1B,GPC5,ADCY2,PSD2,ATP1A2,CAMK2G,TRPM3,GFAP,NTRK3,RFX4,NEBL,SLC1A2,SORBS1,RORA,MACF1,GPM6A,NAV2,HPSE2,ABLIM1,NPAS3,LSAMP,CDH20,CTNND2,TNC,SOX5,NTRK2
1.324e-02	-4.32	SHROOM3 (shroom family member 3)	protein interactions	57619	68	2	19454	50	PARD3,RPS6KA2
1.324e-02	-4.32	PLCH1 (phospholipase C eta 1)	protein interactions	23007	68	2	19454	50	NTRK2,PARD3
1.324e-02	-4.32	circulatory system development	biological process	GO:0072359	933	7	18204	50	NTRK3,NEBL,RORA,ERBB4,SYNE1,PRKCA,NTRK2
1.328e-02	-4.32	env (Envelope surface glycoprotein gp160, precursor)	protein interactions	155971	1501	9	19454	50	CTNNA2,SLC1A2,MGAT4C,TNC,PRKCA,GFAP,NTRK3,ADCY2,NTRK2
1.332e-02	-4.32	medulla	COSMIC cancer mutations	medulla	14778	48	16828	49	RORA,MACF1,NAV2,GPM6A,HPSE2,ABLIM1,SLC1A2,SORBS1,NTRK3,RFX4,NEBL,TRPM3,GFAP,SOX5,NTRK2,CTNND2,TNC,CDH20,NPAS3,LSAMP,KALRN,DCLK2,PITPNC1,MGAT4C,SYNE1,PARD3,SLC14A1,MSI2,NTM,PRKCA,RYR3,RPS6KA2,FMN2,DGKG,DTNA,SFXN5,GLIS3,NRG3,CAMK2G,PSD2,ATP1A2,NDRG2,LRP1B,GPC5,ADCY2,NRXN1,SLC4A4,ERBB4
1.336e-02	-4.32	desmoplastic	COSMIC cancer mutations	desmoplastic	14779	48	16828	49	NTRK3,RFX4,NEBL,TRPM3,GFAP,MACF1,GPM6A,NAV2,RORA,ABLIM1,HPSE2,SLC1A2,SORBS1,CDH20,NPAS3,LSAMP,NTRK2,SOX5,CTNND2,TNC,RPS6KA2,FMN2,DGKG,NTM,PRKCA,RYR3,DTNA,NRG3,SFXN5,GLIS3,DCLK2,KALRN,MGAT4C,PITPNC1,SYNE1,MSI2,SLC14A1,PARD3,LRP1B,GPC5,ADCY2,NDRG2,ERBB4,NRXN1,SLC4A4,CAMK2G,PSD2,ATP1A2
1.337e-02	-4.31	dendrite morphogenesis	biological process	GO:0048813	64	2	18204	50	CTNND2,CTNNA2
1.337e-02	-4.31	actin filament bundle assembly	biological process	GO:0051017	64	2	18204	50	SORBS1,FMN2
1.339e-02	-4.31	prostate-carcinoma-adenocarcinoma	COSMIC cancer mutations	prostate-carcinoma-adenocarcinoma	12379	43	16828	49	SYNE1,SORBS1,SLC1A2,SLC14A1,PARD3,KALRN,RORA,GPM6A,NAV2,MACF1,HPSE2,PITPNC1,MGAT4C,ABLIM1,GLIS3,GFAP,SFXN5,TRPM3,NRG3,NKAIN3,NTRK3,RYR3,PRKCA,NTM,DGKG,FMN2,NEBL,RFX4,CTNND2,PSD2,TNC,ATP1A2,SOX5,NTRK2,NPAS3,NRXN1,ERBB4,LSAMP,NDRG2,ADCY2,GPC5,CDH20,LRP1B
1.339e-02	-4.31	KASH	prosite domains	PS51049	4	1	12186	41	SYNE1
1.339e-02	-4.31	NEBULIN	prosite domains	PS51216	4	1	12186	41	NEBL
1.342e-02	-4.31	salivary_gland-carcinoma-adenoid_cystic_carcinoma	COSMIC cancer mutations	salivary_gland-carcinoma-adenoid_cystic_carcinoma	488	5	16828	49	SYNE1,RORA,CTNND2,RYR3,MGAT4C
1.343e-02	-4.31	Na/HCO3_transpt	interpro domains	IPR003024	5	1	18521	50	SLC4A4
1.343e-02	-4.31	PI_transfer	interpro domains	IPR001666	5	1	18521	50	PITPNC1
1.343e-02	-4.31	Vinculin/catenin	interpro domains	IPR006077	5	1	18521	50	CTNNA2
1.343e-02	-4.31	EGF_Tenascin	interpro domains	IPR041161	5	1	18521	50	TNC
1.343e-02	-4.31	Mtc	interpro domains	IPR004686	5	1	18521	50	SFXN5
1.346e-02	-4.31	cell-cell junction organization	biological process	GO:0045216	181	3	18204	50	PRKCA,CDH20,PARD3
1.347e-02	-4.31	glutamate:sodium symporter activity	molecular function	GO:0015501	5	1	18094	49	SLC1A2
1.347e-02	-4.31	high-affinity L-glutamate transmembrane transporter activity	molecular function	GO:0005314	5	1	18094	49	SLC1A2
1.347e-02	-4.31	neuroligin family protein binding	molecular function	GO:0097109	5	1	18094	49	NRXN1
1.347e-02	-4.31	cytoskeleton-nuclear membrane anchor activity	molecular function	GO:0140444	5	1	18094	49	SYNE1
1.347e-02	-4.31	syndecan binding	molecular function	GO:0045545	5	1	18094	49	TNC
1.354e-02	-4.30	GRB2 (growth factor receptor bound protein 2)	protein interactions	2885	769	6	19454	50	MSI2,NTRK3,NTRK2,SLC1A2,GFAP,ERBB4
1.363e-02	-4.30	temporoparietal	COSMIC cancer mutations	temporoparietal	61	2	16828	49	RYR3,PARD3
1.363e-02	-4.30	central_nervous_system-cerebrum-glioma-astrocytoma_Grade_IV	COSMIC cancer mutations	central_nervous_system-cerebrum-glioma-astrocytoma_Grade_IV	61	2	16828	49	LRP1B,SYNE1
1.366e-02	-4.29	stem cell differentiation	biological process	GO:0048863	182	3	18204	50	GPM6A,ERBB4,MSI2
1.366e-02	-4.29	cellular response to prostaglandin D stimulus	biological process	GO:0071799	5	1	18204	50	TNC
1.366e-02	-4.29	glossopharyngeal nerve development	biological process	GO:0021563	5	1	18204	50	NAV2
1.366e-02	-4.29	synaptic signaling via neuropeptide	biological process	GO:0099538	5	1	18204	50	NTRK2
1.366e-02	-4.29	citrate transport	biological process	GO:0015746	5	1	18204	50	SFXN5
1.366e-02	-4.29	gephyrin clustering involved in postsynaptic density assembly	biological process	GO:0097116	5	1	18204	50	NRXN1
1.366e-02	-4.29	amygdala development	biological process	GO:0021764	5	1	18204	50	ATP1A2
1.366e-02	-4.29	tricarboxylic acid transport	biological process	GO:0006842	5	1	18204	50	SFXN5
1.366e-02	-4.29	polar body extrusion after meiotic divisions	biological process	GO:0040038	5	1	18204	50	FMN2
1.366e-02	-4.29	ERBB2-ERBB4 signaling pathway	biological process	GO:0038135	5	1	18204	50	ERBB4
1.366e-02	-4.29	response to prostaglandin D	biological process	GO:0071798	5	1	18204	50	TNC
1.367e-02	-4.29	neoplasm	COSMIC cancer mutations	neoplasm	14787	48	16828	49	CAMK2G,ATP1A2,PSD2,NDRG2,ADCY2,GPC5,LRP1B,SLC4A4,NRXN1,ERBB4,MGAT4C,KALRN,DCLK2,SLC14A1,PARD3,MSI2,SYNE1,DTNA,RYR3,PRKCA,NTM,DGKG,FMN2,RPS6KA2,NKAIN3,GLIS3,SFXN5,NRG3,SOX5,NTRK2,TNC,CTNND2,CDH20,LSAMP,NPAS3,HPSE2,ABLIM1,RORA,NAV2,GPM6A,MACF1,SORBS1,SLC1A2,NEBL,RFX4,NTRK3,GFAP,TRPM3
1.369e-02	-4.29	Vinculin	pfam domains	PF01044	5	1	17795	49	CTNNA2
1.369e-02	-4.29	IP_trans	pfam domains	PF02121	5	1	17795	49	PITPNC1
1.369e-02	-4.29	EGF_Tenascin	pfam domains	PF18720	5	1	17795	49	TNC
1.369e-02	-4.29	SFXNs	pfam domains	PF03820	5	1	17795	49	SFXN5
1.369e-02	-4.29	main axon	cellular component	GO:0044304	68	2	19108	50	PARD3,SLC1A2
1.371e-02	-4.29	ALPHACATENIN	prints domains	PR00805	4	1	5227	18	CTNNA2
1.372e-02	-4.29	PE/DAG-bd	interpro domains	IPR002219	66	2	18521	50	DGKG,PRKCA
1.377e-02	-4.29	positive regulation of synapse assembly	biological process	GO:0051965	65	2	18204	50	NRXN1,NTRK2
1.377e-02	-4.29	long-term synaptic potentiation	biological process	GO:0060291	65	2	18204	50	GFAP,NTRK2
1.386e-02	-4.28	regulation of carbohydrate metabolic process	biological process	GO:0006109	183	3	18204	50	SORBS1,RORA,SLC4A4
1.387e-02	-4.28	primary_central_nervous_system_lymphoma	COSMIC cancer mutations	primary_central_nervous_system_lymphoma	683	6	16828	49	LRP1B,MACF1,PARD3,NRG3,NRXN1,SYNE1
1.387e-02	-4.28	haematopoietic_and_lymphoid_tissue-central_nervous_system-lymphoid_neoplasm-primary_central_nervous_system_lymphoma	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue-central_nervous_system-lymphoid_neoplasm-primary_central_nervous_system_lymphoma	683	6	16828	49	SYNE1,NRXN1,NRG3,MACF1,PARD3,LRP1B
1.398e-02	-4.27	skin-carcinoma-squamous_cell_carcinoma	COSMIC cancer mutations	skin-carcinoma-squamous_cell_carcinoma	493	5	16828	49	LRP1B,SYNE1,NTRK3,ERBB4,NTRK2
1.399e-02	-4.27	NGFR (nerve growth factor receptor)	protein interactions	4804	70	2	19454	50	NTRK2,NTRK3
1.399e-02	-4.27	PCDH20 (protocadherin 20)	protein interactions	64881	70	2	19454	50	CTNNA2,MGAT4C
1.403e-02	-4.27	bone-extraskeletal-Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour	COSMIC cancer mutations	bone-extraskeletal-Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour	891	7	16828	49	ATP1A2,SYNE1,PSD2,NPAS3,ABLIM1,DGKG,NAV2
1.407e-02	-4.26	S_TK_X	smart domains	SM00133	49	2	9717	36	PRKCA,RPS6KA2
1.408e-02	-4.26	IG_LIKE	prosite domains	PS50835	430	5	12186	41	NTRK3,LSAMP,NTRK2,NTM,KALRN
1.414e-02	-4.26	PIK3R3 (phosphoinositide-3-kinase regulatory subunit 3)	protein interactions	8503	197	3	19454	50	NTRK2,ERBB4,NEBL
1.414e-02	-4.26	FBXO25 (F-box protein 25)	protein interactions	26260	197	3	19454	50	ATP1A2,GFAP,PRKCA
1.418e-02	-4.26	ERBB signaling pathway	biological process	GO:0038127	66	2	18204	50	ERBB4,NRG3
1.424e-02	-4.25	EGF	pfam domains	PF00008	66	2	17795	49	NRXN1,LRP1B
1.427e-02	-4.25	positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction	biological process	GO:0051897	185	3	18204	50	NTRK3,NTRK2,ERBB4
1.427e-02	-4.25	response to growth factor	biological process	GO:0070848	525	5	18204	50	NTRK3,SOX5,TNC,ERBB4,NTRK2
1.430e-02	-4.25	IG	smart domains	SM00409	394	5	9717	36	LSAMP,NTM,NTRK2,NTRK3,KALRN
1.437e-02	-4.24	AKR7L (aldo-keto reductase family 7 like (gene/pseudogene))	protein interactions	246181	71	2	19454	50	MACF1,PARD3
1.450e-02	-4.23	NGF-independant TRKA activation	REACTOME pathways	R-HSA-187024	5	1	10285	30	NTRK2
1.450e-02	-4.23	Disinhibition of SNARE formation	REACTOME pathways	R-HSA-114516	5	1	10285	30	PRKCA
1.455e-02	-4.23	Activation of PKC Through G Protein-Coupled Receptor	SMPDB pathways	SMP0000749	4	1	1369	5	PRKCA
1.465e-02	-4.22	AGC_KINASE_CTER	prosite domains	PS51285	55	2	12186	41	RPS6KA2,PRKCA
1.474e-02	-4.22	NEBU	smart domains	SM00227	4	1	9717	36	NEBL
1.474e-02	-4.22	KASH	smart domains	SM01249	4	1	9717	36	SYNE1
1.476e-02	-4.22	Ppp1cb (protein phosphatase 1 catalytic subunit beta)	protein interactions	19046	72	2	19454	50	ABLIM1,PARD3
1.476e-02	-4.22	VEGFA-VEGFR2 Pathway	REACTOME pathways	R-HSA-4420097	330	4	10285	30	CAMK2G,PRKCA,NRG3,ERBB4
1.491e-02	-4.21	DBN1 (drebrin 1)	protein interactions	1627	370	4	19454	50	ABLIM1,PRKCA,CAMK2G,SOX5
1.501e-02	-4.20	actin filament bundle organization	biological process	GO:0061572	68	2	18204	50	FMN2,SORBS1
1.501e-02	-4.20	extraskeletal	COSMIC cancer mutations	extraskeletal	903	7	16828	49	DGKG,NAV2,ABLIM1,SYNE1,PSD2,NPAS3,ATP1A2
1.503e-02	-4.20	Phospholipase D signaling pathway	KEGG pathways	ko04072	145	3	7161	26	DGKG,ADCY2,PRKCA
1.503e-02	-4.20	Phospholipase D signaling pathway	KEGG pathways	hsa04072	145	3	7161	26	PRKCA,DGKG,ADCY2
1.512e-02	-4.19	neuron to neuron synapse	cellular component	GO:0098984	365	4	19108	50	ERBB4,CTNND2,NTRK2,KALRN
1.520e-02	-4.19	skin-scalp-carcinoma-squamous_cell_carcinoma	COSMIC cancer mutations	skin-scalp-carcinoma-squamous_cell_carcinoma	1596	10	16828	49	SYNE1,NRXN1,GFAP,SLC4A4,ATP1A2,LSAMP,MACF1,RORA,SOX5,GPC5
1.527e-02	-4.18	Constitutive Signaling by Aberrant PI3K in Cancer	REACTOME pathways	R-HSA-2219530	65	2	10285	30	ERBB4,NRG3
1.532e-02	-4.18	SMOC2 (SPARC related modular calcium binding 2)	protein interactions	64094	6	1	19454	50	TNC
1.532e-02	-4.18	SOX1 (SRY-box transcription factor 1)	protein interactions	6656	6	1	19454	50	SOX5
1.532e-02	-4.18	SLC12A5 (solute carrier family 12 member 5)	protein interactions	57468	6	1	19454	50	GPM6A
1.532e-02	-4.18	LBX2 (ladybird homeobox 2)	protein interactions	85474	6	1	19454	50	GFAP
1.532e-02	-4.18	Zbtb2 (zinc finger and BTB domain containing 2)	protein interactions	381990	6	1	19454	50	SORBS1
1.532e-02	-4.18	CIBAR2 (CBY1 interacting BAR domain containing 2)	protein interactions	339145	6	1	19454	50	CAMK2G
1.532e-02	-4.18	DRP2 (dystrophin related protein 2)	protein interactions	1821	6	1	19454	50	DTNA
1.532e-02	-4.18	Csnk1d (casein kinase 1, delta)	protein interactions	64462	6	1	19454	50	PRKCA
1.532e-02	-4.18	Itch (itchy, E3 ubiquitin protein ligase)	protein interactions	16396	6	1	19454	50	GLIS3
1.532e-02	-4.18	NRG4 (neuregulin 4)	protein interactions	145957	6	1	19454	50	ERBB4
1.532e-02	-4.18	CYRIA (CYFIP related Rac1 interactor A)	protein interactions	81553	6	1	19454	50	GPM6A
1.532e-02	-4.18	SYTL3 (synaptotagmin like 3)	protein interactions	94120	6	1	19454	50	NRXN1
1.532e-02	-4.18	Tiam2 (T cell lymphoma invasion and metastasis 2)	protein interactions	24001	6	1	19454	50	DTNA
1.532e-02	-4.18	ARMS2 (age-related maculopathy susceptibility 2)	protein interactions	387715	6	1	19454	50	PRKCA
1.532e-02	-4.18	SOX11 (SRY-box transcription factor 11)	protein interactions	6664	6	1	19454	50	SOX5
1.532e-02	-4.18	ADCY1 (adenylate cyclase 1)	protein interactions	107	6	1	19454	50	ADCY2
1.535e-02	-4.18	Immunoglobulin	interpro domains	IPR013151	70	2	18521	50	NTM,NTRK3
1.539e-02	-4.17	skin-ankle-malignant_melanoma-acral_lentiginous	COSMIC cancer mutations	skin-ankle-malignant_melanoma-acral_lentiginous	330	4	16828	49	KALRN,ERBB4,NRG3,PARD3
1.541e-02	-4.17	GJA1 (gap junction protein alpha 1)	protein interactions	2697	572	5	19454	50	ERBB4,MACF1,PRKCA,DTNA,PARD3
1.546e-02	-4.17	-	gene3d domains	6.10.140.620	5	1	14470	45	CAMK2G
1.549e-02	-4.17	skin-ear-carcinoma-squamous_cell_carcinoma	COSMIC cancer mutations	skin-ear-carcinoma-squamous_cell_carcinoma	506	5	16828	49	SLC14A1,TNC,MGAT4C,NPAS3,RPS6KA2
1.550e-02	-4.17	LIM	pfam domains	PF00412	69	2	17795	49	NEBL,ABLIM1
1.552e-02	-4.17	CASK (calcium/calmodulin dependent serine protein kinase)	protein interactions	8573	204	3	19454	50	NRXN1,ABLIM1,DTNA
1.554e-02	-4.16	TEC (tec protein tyrosine kinase)	protein interactions	7006	74	2	19454	50	MSI2,ERBB4
1.555e-02	-4.16	heterocyclic compound binding	molecular function	GO:1901363	2263	12	18094	49	DCLK2,DGKG,NTRK3,RPS6KA2,NTRK2,CAMK2G,ATP1A2,NAV2,ADCY2,ERBB4,PRKCA,KALRN
1.560e-02	-4.16	PAR polarity complex	cellular component	GO:0120157	6	1	19108	50	PARD3
1.561e-02	-4.16	monoatomic ion transport	biological process	GO:0006811	964	7	18204	50	GPM6A,ATP1A2,TRPM3,SLC4A4,RYR3,SLC1A2,SFXN5
1.576e-02	-4.15	Znf_LIM	interpro domains	IPR001781	71	2	18521	50	NEBL,ABLIM1
1.578e-02	-4.15	ion binding	molecular function	GO:0043167	6007	24	18094	49	NRXN1,ERBB4,KALRN,MACF1,CAMK2G,NTRK2,RPS6KA2,DCLK2,DGKG,PARD3,NAV2,SLC1A2,RYR3,ATP1A2,ADCY2,LRP1B,PITPNC1,MGAT4C,PRKCA,GLIS3,ABLIM1,NTRK3,RORA,DTNA
1.584e-02	-4.15	Signaling by SCF-KIT	REACTOME pathways	R-HSA-1433557	337	4	10285	30	PRKCA,CAMK2G,NRG3,ERBB4
1.586e-02	-4.14	membrane protein complex	cellular component	GO:0098796	1261	8	19108	50	SORBS1,ATP1A2,SLC1A2,CTNNA2,SYNE1,PRKCA,RYR3,CDH20
1.592e-02	-4.14	cellular process	biological process	GO:0009987	14996	47	18204	50	NRG3,ATP1A2,RORA,RFX4,RPS6KA2,ABLIM1,PRKCA,GPM6A,SOX5,LSAMP,ADCY2,CDH20,TNC,GPC5,RYR3,MACF1,NDRG2,CAMK2G,SLC4A4,GFAP,NAV2,SYNE1,MSI2,HPSE2,SFXN5,SLC1A2,NTRK2,FMN2,DCLK2,NRXN1,NEBL,DTNA,PARD3,NTRK3,TRPM3,CTNND2,CTNNA2,SLC14A1,PITPNC1,KALRN,SORBS1,NTM,MGAT4C,ERBB4,DGKG,GLIS3,LRP1B
1.592e-02	-4.14	ig	pfam domains	PF00047	70	2	17795	49	NTM,NTRK3
1.594e-02	-4.14	UNC5B (unc-5 netrin receptor B)	protein interactions	219699	75	2	19454	50	NTRK3,PARD3
1.599e-02	-4.14	Signaling by VEGF	REACTOME pathways	R-HSA-194138	338	4	10285	30	NRG3,ERBB4,PRKCA,CAMK2G
1.600e-02	-4.13	other	COSMIC cancer mutations	other	14843	48	16828	49	NPAS3,LSAMP,CDH20,CTNND2,TNC,NTRK2,SOX5,TRPM3,GFAP,NTRK3,RFX4,NEBL,SLC1A2,SORBS1,MACF1,NAV2,GPM6A,RORA,ABLIM1,HPSE2,ERBB4,NRXN1,SLC4A4,GPC5,LRP1B,ADCY2,NDRG2,PSD2,ATP1A2,CAMK2G,NRG3,SFXN5,GLIS3,NKAIN3,RPS6KA2,DGKG,FMN2,PRKCA,NTM,RYR3,DTNA,SYNE1,MSI2,SLC14A1,PARD3,DCLK2,KALRN,MGAT4C
1.609e-02	-4.13	G3BP1 (G3BP stress granule assembly factor 1)	protein interactions	10146	799	6	19454	50	CTNNA2,SYNE1,SORBS1,MACF1,MSI2,SOX5
1.609e-02	-4.13	RyR/IP3R_RIH_dom_sf	interpro domains	IPR035910	6	1	18521	50	RYR3
1.609e-02	-4.13	PH_dom-spectrin-type	interpro domains	IPR001605	6	1	18521	50	PSD2
1.609e-02	-4.13	GAR_dom_sf	interpro domains	IPR036534	6	1	18521	50	MACF1
1.609e-02	-4.13	Glypican	interpro domains	IPR001863	6	1	18521	50	GPC5
1.609e-02	-4.13	Adcy_conserved_dom	interpro domains	IPR009398	6	1	18521	50	ADCY2
1.609e-02	-4.13	Ribosomal_S6_kinase_II	interpro domains	IPR016239	6	1	18521	50	RPS6KA2
1.609e-02	-4.13	P-type_ATPase_IIC	interpro domains	IPR005775	6	1	18521	50	ATP1A2
1.609e-02	-4.13	GLI-like	interpro domains	IPR043359	6	1	18521	50	GLIS3
1.609e-02	-4.13	EF-hand_dom_typ1	interpro domains	IPR015153	6	1	18521	50	DTNA
1.609e-02	-4.13	Ins145_P3_rcpt	interpro domains	IPR014821	6	1	18521	50	RYR3
1.609e-02	-4.13	Glypican_CS	interpro domains	IPR019803	6	1	18521	50	GPC5
1.609e-02	-4.13	EF-hand_dom_typ2	interpro domains	IPR015154	6	1	18521	50	DTNA
1.609e-02	-4.13	Ryanodine_IP3_receptor	interpro domains	IPR015925	6	1	18521	50	RYR3
1.609e-02	-4.13	RIH_assoc-dom	interpro domains	IPR013662	6	1	18521	50	RYR3
1.609e-02	-4.13	Desmoplakin_SH3	interpro domains	IPR041615	6	1	18521	50	MACF1
1.609e-02	-4.13	GAR_dom	interpro domains	IPR003108	6	1	18521	50	MACF1
1.609e-02	-4.13	Syndecan/Neurexin_dom	interpro domains	IPR027789	6	1	18521	50	NRXN1
1.609e-02	-4.13	GF_recep_IV	interpro domains	IPR032778	6	1	18521	50	ERBB4
1.609e-02	-4.13	RIH_dom	interpro domains	IPR000699	6	1	18521	50	RYR3
1.609e-02	-4.13	large_cell	COSMIC cancer mutations	large_cell	14845	48	16828	49	LRP1B,GPC5,ADCY2,NDRG2,ERBB4,NRXN1,SLC4A4,CAMK2G,PSD2,ATP1A2,RPS6KA2,FMN2,DGKG,PRKCA,NTM,RYR3,DTNA,NRG3,SFXN5,GLIS3,DCLK2,KALRN,MGAT4C,PITPNC1,SYNE1,MSI2,SLC14A1,PARD3,CDH20,NPAS3,LSAMP,NTRK2,SOX5,CTNND2,TNC,NTRK3,RFX4,NEBL,TRPM3,GFAP,MACF1,GPM6A,NAV2,RORA,ABLIM1,HPSE2,SLC1A2,SORBS1
1.614e-02	-4.13	sodium:bicarbonate symporter activity	molecular function	GO:0008510	6	1	18094	49	SLC4A4
1.614e-02	-4.13	steroid hormone binding	molecular function	GO:1990239	6	1	18094	49	ATP1A2
1.614e-02	-4.13	calcium-induced calcium release activity	molecular function	GO:0048763	6	1	18094	49	RYR3
1.615e-02	-4.13	organelle organization	biological process	GO:0006996	3091	15	18204	50	DCLK2,FMN2,NRXN1,MACF1,RFX4,SORBS1,PRKCA,ABLIM1,PARD3,NEBL,GFAP,ERBB4,SYNE1,NAV2,CTNNA2
1.617e-02	-4.12	Signaling by PTK6	REACTOME pathways	R-HSA-8848021	67	2	10285	30	NRG3,ERBB4
1.619e-02	-4.12	presynapse	cellular component	GO:0098793	569	5	19108	50	NTRK2,NRXN1,ERBB4,GPM6A,SLC1A2
1.621e-02	-4.12	ZF_DAG_PE_1	prosite domains	PS00479	58	2	12186	41	DGKG,PRKCA
1.628e-02	-4.12	cerebrum	COSMIC cancer mutations	cerebrum	67	2	16828	49	SYNE1,LRP1B
1.628e-02	-4.12	haematopoietic_and_lymphoid_tissue-soft_tissue-lymphoid_neoplasm-diffuse_large_B_cell_lymphoma	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue-soft_tissue-lymphoid_neoplasm-diffuse_large_B_cell_lymphoma	67	2	16828	49	SYNE1,LRP1B
1.635e-02	-4.11	RAPGEF6 (Rap guanine nucleotide exchange factor 6)	protein interactions	51735	76	2	19454	50	PARD3,NTRK3
1.637e-02	-4.11	asymmetric neuroblast division	biological process	GO:0055059	6	1	18204	50	SOX5
1.637e-02	-4.11	vascular associated smooth muscle cell proliferation	biological process	GO:1990874	6	1	18204	50	NDRG2
1.637e-02	-4.11	positive regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway	biological process	GO:0106071	6	1	18204	50	PRKCA
1.637e-02	-4.11	establishment of meiotic spindle localization	biological process	GO:0051295	6	1	18204	50	FMN2
1.637e-02	-4.11	postsynaptic density protein 95 clustering	biological process	GO:0097119	6	1	18204	50	NRXN1
1.637e-02	-4.11	L-aspartate import across plasma membrane	biological process	GO:0140009	6	1	18204	50	SLC1A2
1.637e-02	-4.11	vocal learning	biological process	GO:0042297	6	1	18204	50	NRXN1
1.637e-02	-4.11	imitative learning	biological process	GO:0098596	6	1	18204	50	NRXN1
1.637e-02	-4.11	mammary gland formation	biological process	GO:0060592	6	1	18204	50	NRG3
1.641e-02	-4.11	Ins145_P3_rec	pfam domains	PF08709	6	1	17795	49	RYR3
1.641e-02	-4.11	GAS2	pfam domains	PF02187	6	1	17795	49	MACF1
1.641e-02	-4.11	Plectin	pfam domains	PF00681	6	1	17795	49	MACF1
1.641e-02	-4.11	GF_recep_IV	pfam domains	PF14843	6	1	17795	49	ERBB4
1.641e-02	-4.11	EF-hand_2	pfam domains	PF09068	6	1	17795	49	DTNA
1.641e-02	-4.11	RIH_assoc	pfam domains	PF08454	6	1	17795	49	RYR3
1.641e-02	-4.11	Glypican	pfam domains	PF01153	6	1	17795	49	GPC5
1.641e-02	-4.11	Syndecan	pfam domains	PF01034	6	1	17795	49	NRXN1
1.641e-02	-4.11	EF-hand_3	pfam domains	PF09069	6	1	17795	49	DTNA
1.641e-02	-4.11	Adcy_cons_dom	pfam domains	PF06327	6	1	17795	49	ADCY2
1.641e-02	-4.11	RYDR_ITPR	pfam domains	PF01365	6	1	17795	49	RYR3
1.641e-02	-4.11	SH3_10	pfam domains	PF17902	6	1	17795	49	MACF1
1.675e-02	-4.09	ABI1 (abl interactor 1)	protein interactions	10006	210	3	19454	50	SORBS1,RPS6KA2,NTRK3
1.687e-02	-4.08	-	gene3d domains	3.30.60.20	64	2	14470	45	DGKG,PRKCA
1.691e-02	-4.08	sarcoplasmic reticulum	cellular component	GO:0016529	76	2	19108	50	RYR3,CAMK2G
1.693e-02	-4.08	LRRNT	smart domains	SM00013	54	2	9717	36	NTRK3,NTRK2
1.711e-02	-4.07	NAHCO3TRSPRT	prints domains	PR01232	5	1	5227	18	SLC4A4
1.711e-02	-4.07	PITRANSFER	prints domains	PR00391	5	1	5227	18	PITPNC1
1.711e-02	-4.07	positive regulation of cell projection organization	biological process	GO:0031346	361	4	18204	50	GPM6A,NTRK3,MACF1,NTRK2
1.716e-02	-4.07	MARCKS (myristoylated alanine rich protein kinase C substrate)	protein interactions	4082	588	5	19454	50	DTNA,RPS6KA2,ABLIM1,PRKCA,MACF1
1.717e-02	-4.06	ANKRD40 (ankyrin repeat domain 40)	protein interactions	91369	78	2	19454	50	MSI2,SOX5
1.717e-02	-4.06	ATOH1 (atonal bHLH transcription factor 1)	protein interactions	474	78	2	19454	50	GFAP,MACF1
1.722e-02	-4.06	regulation of signal transduction	biological process	GO:0009966	3114	15	18204	50	GPC5,KALRN,NRXN1,RORA,MACF1,NDRG2,SORBS1,PRKCA,NTRK3,ERBB4,DGKG,CTNND2,PSD2,SYNE1,NTRK2
1.738e-02	-4.05	RSK activation	REACTOME pathways	R-HSA-444257	6	1	10285	30	RPS6KA2
1.738e-02	-4.05	Activation of TRKA receptors	REACTOME pathways	R-HSA-187015	6	1	10285	30	NTRK2
1.739e-02	-4.05	NUMB (NUMB endocytic adaptor protein)	protein interactions	8650	213	3	19454	50	PARD3,NTRK3,PRKCA
1.759e-02	-4.04	KRTAP3-2 (keratin associated protein 3-2)	protein interactions	83897	79	2	19454	50	NTM,GFAP
1.761e-02	-4.04	DLG1 (discs large MAGUK scaffold protein 1)	protein interactions	1739	214	3	19454	50	PARD3,NTRK3,ERBB4
1.761e-02	-4.04	NCK1 (NCK adaptor protein 1)	protein interactions	4690	214	3	19454	50	ERBB4,NTRK3,NTRK2
1.765e-02	-4.04	animal organ morphogenesis	biological process	GO:0009887	988	7	18204	50	CTNNA2,ABLIM1,NTRK2,NRG3,SOX5,ERBB4,TNC
1.786e-02	-4.03	Smurf1 (SMAD specific E3 ubiquitin protein ligase 1)	protein interactions	75788	7	1	19454	50	GLIS3
1.786e-02	-4.03	Nde1 (nudE neurodevelopment protein 1)	protein interactions	67203	7	1	19454	50	SYNE1
1.786e-02	-4.03	ABCC12 (ATP binding cassette subfamily C member 12)	protein interactions	94160	7	1	19454	50	NPAS3
1.790e-02	-4.02	axonogenesis	biological process	GO:0007409	366	4	18204	50	PARD3,CTNNA2,NRXN1,KALRN
1.801e-02	-4.02	GJB1 (gap junction protein beta 1)	protein interactions	2705	80	2	19454	50	MSI2,PRKCA
1.804e-02	-4.01	ATP2B1 (ATPase plasma membrane Ca2+ transporting 1)	protein interactions	490	216	3	19454	50	PRKCA,NTRK2,PARD3
1.815e-02	-4.01	Corticotropin Activation of Cortisol Production	SMPDB pathways	SMP0000310	5	1	1369	5	ADCY2
1.815e-02	-4.01	Ion Channel and Phorbal Esters Signaling Pathway	SMPDB pathways	SMP0090032	5	1	1369	5	PRKCA
1.818e-02	-4.01	dendritic spine head	cellular component	GO:0044327	7	1	19108	50	SYNE1
1.835e-02	-4.00	PIK3R1 (phosphoinositide-3-kinase regulatory subunit 1)	protein interactions	5295	394	4	19454	50	NTRK3,NTRK2,RPS6KA2,ERBB4
1.843e-02	-3.99	FAM135A (family with sequence similarity 135 member A)	protein interactions	57579	81	2	19454	50	NTRK2,NTRK3
1.852e-02	-3.99	Gas2-like domain	gene3d domains	3.30.920.20	6	1	14470	45	MACF1
1.852e-02	-3.99	Plakin repeat	gene3d domains	3.90.1290.10	6	1	14470	45	MACF1
1.852e-02	-3.99	IP3 receptor type 1 binding core, RIH domain	gene3d domains	1.25.10.30	6	1	14470	45	RYR3
1.855e-02	-3.99	Insulin Signaling	WikiPathways	WP481	161	3	5310	19	SORBS1,PRKCA,RPS6KA2
1.865e-02	-3.98	cortisol_producing	COSMIC cancer mutations	cortisol_producing	72	2	16828	49	FMN2,LRP1B
1.865e-02	-3.98	adrenal_gland-adrenal_gland-adrenal_cortical_adenoma-cortisol_producing	COSMIC cancer mutations	adrenal_gland-adrenal_gland-adrenal_cortical_adenoma-cortisol_producing	72	2	16828	49	LRP1B,FMN2
1.871e-02	-3.98	TRIM29 (tripartite motif containing 29)	protein interactions	23650	219	3	19454	50	NKAIN3,SYNE1,PRKCA
1.871e-02	-3.98	positive regulation of biological process	biological process	GO:0048518	6326	25	18204	50	NPAS3,PARD3,GPM6A,NTRK3,SOX5,RPS6KA2,RFX4,PRKCA,FMN2,ATP1A2,RORA,NRXN1,SYNE1,SFXN5,HPSE2,NTRK2,SLC1A2,SLC4A4,GFAP,GLIS3,ERBB4,MACF1,SORBS1,TNC,GPC5
1.872e-02	-3.98	calcium ion transmembrane transport	biological process	GO:0070588	205	3	18204	50	TRPM3,RYR3,GPM6A
1.875e-02	-3.98	Plakin_repeat_sf	interpro domains	IPR035915	7	1	18521	50	MACF1
1.875e-02	-3.98	Na-dicarboxylate_symporter	interpro domains	IPR001991	7	1	18521	50	SLC1A2
1.875e-02	-3.98	Furin-like_Cys-rich_dom	interpro domains	IPR006211	7	1	18521	50	ERBB4
1.875e-02	-3.98	Na-dicarboxylate_symporter_CS	interpro domains	IPR018107	7	1	18521	50	SLC1A2
1.875e-02	-3.98	Rcpt_L-dom	interpro domains	IPR000494	7	1	18521	50	ERBB4
1.875e-02	-3.98	Ammonium/urea_transptr	interpro domains	IPR029020	7	1	18521	50	SLC14A1
1.875e-02	-3.98	Na:dicarbo_symporter_sf	interpro domains	IPR036458	7	1	18521	50	SLC1A2
1.875e-02	-3.98	Alpha-catenin/vinculin-like_sf	interpro domains	IPR036723	7	1	18521	50	CTNNA2
1.875e-02	-3.98	Plectin_repeat	interpro domains	IPR001101	7	1	18521	50	MACF1
1.875e-02	-3.98	Intermed_filament_DNA-bd	interpro domains	IPR006821	7	1	18521	50	GFAP
1.875e-02	-3.98	Plakophilin/d_Catenin	interpro domains	IPR028435	7	1	18521	50	CTNND2
1.875e-02	-3.98	Rcpt_L-dom_sf	interpro domains	IPR036941	7	1	18521	50	ERBB4
1.881e-02	-3.97	calcium-dependent protein serine/threonine phosphatase activity	molecular function	GO:0004723	7	1	18094	49	CAMK2G
1.881e-02	-3.97	P-type sodium transporter activity	molecular function	GO:0008554	7	1	18094	49	ATP1A2
1.881e-02	-3.97	P-type sodium:potassium-exchanging transporter activity	molecular function	GO:0005391	7	1	18094	49	ATP1A2
1.881e-02	-3.97	phosphatidic acid transfer activity	molecular function	GO:1990050	7	1	18094	49	PITPNC1
1.881e-02	-3.97	ribosomal protein S6 kinase activity	molecular function	GO:0004711	7	1	18094	49	RPS6KA2
1.895e-02	-3.97	ZF_DAG_PE_2	prosite domains	PS50081	63	2	12186	41	PRKCA,DGKG
1.897e-02	-3.96	human chr9p24.2	chromosome location	human chr9p24.2	10	1	26134	50	GLIS3
1.898e-02	-3.96	regulation of synaptic transmission, glutamatergic	biological process	GO:0051966	77	2	18204	50	ATP1A2,NRXN1
1.898e-02	-3.96	neural retina development	biological process	GO:0003407	77	2	18204	50	GPM6A,NTRK2
1.898e-02	-3.96	positive regulation of axonogenesis	biological process	GO:0050772	77	2	18204	50	MACF1,NTRK2
1.907e-02	-3.96	negative regulation of Arp2/3 complex-mediated actin nucleation	biological process	GO:0034316	7	1	18204	50	CTNNA2
1.907e-02	-3.96	parallel actin filament bundle assembly	biological process	GO:0030046	7	1	18204	50	FMN2
1.907e-02	-3.96	observational learning	biological process	GO:0098597	7	1	18204	50	NRXN1
1.907e-02	-3.96	cellular response to magnesium ion	biological process	GO:0071286	7	1	18204	50	RYR3
1.907e-02	-3.96	peripheral nervous system axon regeneration	biological process	GO:0014012	7	1	18204	50	TNC
1.907e-02	-3.96	chromosome movement towards spindle pole	biological process	GO:0051305	7	1	18204	50	FMN2
1.907e-02	-3.96	interneuron migration from the subpallium to the cortex	biological process	GO:0021830	7	1	18204	50	NRG3
1.912e-02	-3.96	Furin-like	pfam domains	PF00757	7	1	17795	49	ERBB4
1.912e-02	-3.96	Recep_L_domain	pfam domains	PF01030	7	1	17795	49	ERBB4
1.912e-02	-3.96	SDF	pfam domains	PF00375	7	1	17795	49	SLC1A2
1.912e-02	-3.96	Filament_head	pfam domains	PF04732	7	1	17795	49	GFAP
1.930e-02	-3.95	ARHGEF10 (Rho guanine nucleotide exchange factor 10)	protein interactions	9639	83	2	19454	50	NTRK3,NTRK2
1.930e-02	-3.95	SYT1 (synaptotagmin 1)	protein interactions	6857	83	2	19454	50	GPM6A,NRXN1
1.937e-02	-3.94	sarcomere	cellular component	GO:0030017	218	3	19108	50	NEBL,SYNE1,RYR3
1.939e-02	-3.94	PKP2 (plakophilin 2)	protein interactions	5318	222	3	19454	50	PARD3,NTRK3,NTRK2
1.939e-02	-3.94	PSEN1 (presenilin 1)	protein interactions	5663	222	3	19454	50	GFAP,CTNND2,DTNA
1.939e-02	-3.94	YWHAQ (tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein theta)	protein interactions	10971	1076	7	19454	50	PARD3,SORBS1,MACF1,NAV2,DCLK2,PRKCA,ABLIM1
1.944e-02	-3.94	regulation of glucose transmembrane transport	biological process	GO:0010827	78	2	18204	50	SLC1A2,SORBS1
1.944e-02	-3.94	positive regulation of carbohydrate metabolic process	biological process	GO:0045913	78	2	18204	50	SLC4A4,SORBS1
1.954e-02	-3.94	SH3-like_dom_sf	interpro domains	IPR036028	212	3	18521	50	NEBL,SORBS1,KALRN
1.974e-02	-3.93	PSEN2 (presenilin 2)	protein interactions	5664	84	2	19454	50	GFAP,CTNND2
1.976e-02	-3.92	regulation of localization	biological process	GO:0032879	2028	11	18204	50	GPC5,CAMK2G,ERBB4,GFAP,DCLK2,ATP1A2,SLC1A2,SORBS1,NKAIN3,SYNE1,RYR3
1.985e-02	-3.92	PLEKHA5 (pleckstrin homology domain containing A5)	protein interactions	54477	224	3	19454	50	RPS6KA2,NTRK3,PARD3
1.985e-02	-3.92	solute:sodium symporter activity	molecular function	GO:0015370	80	2	18094	49	SLC4A4,SLC1A2
1.989e-02	-3.92	plasma membrane protein complex	cellular component	GO:0098797	600	5	19108	50	SORBS1,PRKCA,CDH20,ATP1A2,CTNNA2
1.996e-02	-3.91	caveola	cellular component	GO:0005901	83	2	19108	50	SORBS1,ATP1A2
2.002e-02	-3.91	GLYPICAN	prosite domains	PS01207	6	1	12186	41	GPC5
2.002e-02	-3.91	GAR	prosite domains	PS51460	6	1	12186	41	MACF1
2.018e-02	-3.90	CREM (cAMP responsive element modulator)	protein interactions	1390	85	2	19454	50	CAMK2G,PRKCA
2.021e-02	-3.90	stomach-carcinoma-mixed_adenosquamous_carcinoma	COSMIC cancer mutations	stomach-carcinoma-mixed_adenosquamous_carcinoma	7	1	16828	49	NTRK3
2.025e-02	-3.90	CREB phosphorylation	REACTOME pathways	R-HSA-199920	7	1	10285	30	RPS6KA2
2.038e-02	-3.89	CD163 (CD163 molecule)	protein interactions	9332	8	1	19454	50	PRKCA
2.038e-02	-3.89	NKAIN3 (sodium/potassium transporting ATPase interacting 3)	protein interactions	286183	8	1	19454	50	GFAP
2.038e-02	-3.89	Prkca (protein kinase C, alpha)	protein interactions	24680	8	1	19454	50	PRKCA
2.038e-02	-3.89	Marcks (myristoylated alanine rich protein kinase C substrate)	protein interactions	17118	8	1	19454	50	PRKCA
2.038e-02	-3.89	UBALD2 (UBA like domain containing 2)	protein interactions	283991	8	1	19454	50	GFAP
2.038e-02	-3.89	INSM1 (INSM transcriptional repressor 1)	protein interactions	3642	8	1	19454	50	SORBS1
2.049e-02	-3.89	SPECTRINPH	prints domains	PR00683	6	1	5227	18	PSD2
2.051e-02	-3.89	EGF_1	prosite domains	PS00022	174	3	12186	41	TNC,NRG3,LRP1B
2.055e-02	-3.88	PRKCD (protein kinase C delta)	protein interactions	5580	227	3	19454	50	CAMK2G,MACF1,PRKCA
2.063e-02	-3.88	SYNJ1 (synaptojanin 1)	protein interactions	8867	86	2	19454	50	SORBS1,GPM6A
2.069e-02	-3.88	protein binding	molecular function	GO:0005515	13983	44	18094	49	NRG3,ABLIM1,RFX4,GPC5,LRP1B,CTNND2,ADCY2,PITPNC1,GLIS3,SOX5,SYNE1,PRKCA,NPAS3,TNC,FMN2,CAMK2G,GFAP,RYR3,ATP1A2,MSI2,KALRN,SORBS1,MACF1,NTRK3,SFXN5,HPSE2,RORA,DTNA,NDRG2,NEBL,NTM,RPS6KA2,NTRK2,GPM6A,PARD3,DCLK2,CTNNA2,CDH20,NAV2,SLC4A4,LSAMP,SLC1A2,NRXN1,ERBB4
2.073e-02	-3.88	NOTCH2 (notch receptor 2)	protein interactions	4853	409	4	19454	50	NTRK3,PARD3,NTRK2,RPS6KA2
2.075e-02	-3.88	zonula adherens	cellular component	GO:0005915	8	1	19108	50	SORBS1
2.101e-02	-3.86	EF_hand_dom	interpro domains	IPR002048	218	3	18521	50	MACF1,RYR3,DGKG
2.103e-02	-3.86	YKT6 (YKT6 v-SNARE homolog)	protein interactions	10652	229	3	19454	50	NTRK3,GPM6A,RPS6KA2
2.103e-02	-3.86	PCNT (pericentrin)	protein interactions	5116	229	3	19454	50	KALRN,MACF1,SYNE1
2.106e-02	-3.86	eye-uveal_tract-malignant_melanoma-spindle	COSMIC cancer mutations	eye-uveal_tract-malignant_melanoma-spindle	363	4	16828	49	CTNND2,KALRN,TRPM3,MACF1
2.115e-02	-3.86	Cys-rich_flank_reg_C	interpro domains	IPR000483	83	2	18521	50	NTRK3,NTRK2
2.126e-02	-3.85	skin-leg-malignant_melanoma	COSMIC cancer mutations	skin-leg-malignant_melanoma	549	5	16828	49	LRP1B,NEBL,NRG3,SYNE1,NTRK3
2.127e-02	-3.85	DST (dystonin)	protein interactions	667	230	3	19454	50	ATP1A2,NTRK2,PARD3
2.140e-02	-3.84	PH_9	interpro domains	IPR041681	8	1	18521	50	PSD2
2.140e-02	-3.84	RFX-like	interpro domains	IPR039779	8	1	18521	50	RFX4
2.140e-02	-3.84	Plakin	interpro domains	IPR043197	8	1	18521	50	MACF1
2.140e-02	-3.84	AC_N	interpro domains	IPR032628	8	1	18521	50	ADCY2
2.140e-02	-3.84	Villin_headpiece	interpro domains	IPR003128	8	1	18521	50	ABLIM1
2.140e-02	-3.84	TRPM_SLOG	interpro domains	IPR041491	8	1	18521	50	TRPM3
2.140e-02	-3.84	Adcy	interpro domains	IPR030672	8	1	18521	50	ADCY2
2.140e-02	-3.84	Villin_headpiece_dom_sf	interpro domains	IPR036886	8	1	18521	50	ABLIM1
2.140e-02	-3.84	positive regulation of cellular process	biological process	GO:0048522	5719	23	18204	50	SYNE1,NTRK2,SLC1A2,HPSE2,NPAS3,NTRK3,PARD3,GPM6A,ERBB4,GFAP,SOX5,GLIS3,SLC4A4,RFX4,MACF1,RPS6KA2,SORBS1,PRKCA,FMN2,GPC5,TNC,NRXN1,RORA
2.146e-02	-3.84	sodium ion binding	molecular function	GO:0031402	8	1	18094	49	ATP1A2
2.146e-02	-3.84	urea transmembrane transporter activity	molecular function	GO:0015204	8	1	18094	49	SLC14A1
2.146e-02	-3.84	P-type potassium transmembrane transporter activity	molecular function	GO:0008556	8	1	18094	49	ATP1A2
2.153e-02	-3.84	TIMP3 (TIMP metallopeptidase inhibitor 3)	protein interactions	7078	88	2	19454	50	LRP1B,NTRK3
2.157e-02	-3.84	Sodium:dicarboxylate symporter	gene3d domains	1.10.3860.10	7	1	14470	45	SLC1A2
2.157e-02	-3.84	Receptor L-domain	gene3d domains	3.80.20.20	7	1	14470	45	ERBB4
2.157e-02	-3.84	Ammonium transporter AmtB like domains	gene3d domains	1.10.3430.10	7	1	14470	45	SLC14A1
2.161e-02	-3.83	Cysteine Rich Protein	gene3d domains	2.10.110.10	73	2	14470	45	NEBL,ABLIM1
2.172e-02	-3.83	regulation of cell junction assembly	biological process	GO:1901888	217	3	18204	50	NTRK2,NRXN1,MACF1
2.175e-02	-3.83	CTNND1 (catenin delta 1)	protein interactions	1500	232	3	19454	50	NTRK3,PARD3,RPS6KA2
2.175e-02	-3.83	Dopamine Activation of Neurological Reward System	SMPDB pathways	SMP0000308	6	1	1369	5	ADCY2
2.175e-02	-3.83	Phospholipase C Signaling Pathway	SMPDB pathways	SMP0063783	6	1	1369	5	PRKCA
2.175e-02	-3.83	Intracellular Signalling Through PGD2 receptor and Prostaglandin D2	SMPDB pathways	SMP0000343	6	1	1369	5	ADCY2
2.177e-02	-3.83	cell proliferation in hindbrain	biological process	GO:0021534	8	1	18204	50	RORA
2.177e-02	-3.83	smooth muscle cell proliferation	biological process	GO:0048659	8	1	18204	50	NDRG2
2.177e-02	-3.83	regulation of chaperone-mediated autophagy	biological process	GO:1904714	8	1	18204	50	GFAP
2.177e-02	-3.83	cerebellar granule cell precursor proliferation	biological process	GO:0021930	8	1	18204	50	RORA
2.177e-02	-3.83	regulation of synapse structural plasticity	biological process	GO:0051823	8	1	18204	50	CTNNA2
2.177e-02	-3.83	meiotic cytokinesis	biological process	GO:0033206	8	1	18204	50	FMN2
2.177e-02	-3.83	mitotic nuclear membrane disassembly	biological process	GO:0007077	8	1	18204	50	PRKCA
2.177e-02	-3.83	regulation of L-glutamate import across plasma membrane	biological process	GO:0002036	8	1	18204	50	ATP1A2
2.177e-02	-3.83	cell proliferation in external granule layer	biological process	GO:0021924	8	1	18204	50	RORA
2.182e-02	-3.82	DCX	pfam domains	PF03607	8	1	17795	49	DCLK2
2.182e-02	-3.82	PH_9	pfam domains	PF15410	8	1	17795	49	PSD2
2.182e-02	-3.82	VHP	pfam domains	PF02209	8	1	17795	49	ABLIM1
2.182e-02	-3.82	LSDAT_euk	pfam domains	PF18139	8	1	17795	49	TRPM3
2.182e-02	-3.82	AC_N	pfam domains	PF16214	8	1	17795	49	ADCY2
2.186e-02	-3.82	skin-upper_arm-malignant_melanoma	COSMIC cancer mutations	skin-upper_arm-malignant_melanoma	553	5	16828	49	LRP1B,SYNE1,SLC4A4,ERBB4,FMN2
2.194e-02	-3.82	regulation of cell population proliferation	biological process	GO:0042127	1790	10	18204	50	GFAP,TNC,ERBB4,NTRK3,PRKCA,NDRG2,NTRK2,HPSE2,SYNE1,RPS6KA2
2.197e-02	-3.82	receptor complex	cellular component	GO:0043235	409	4	19108	50	NTRK3,ERBB4,NTRK2,LRP1B
2.199e-02	-3.82	PEA15 (proliferation and apoptosis adaptor protein 15)	protein interactions	8682	89	2	19454	50	CAMK2G,PRKCA
2.203e-02	-3.82	GAS2	smart domains	SM00243	6	1	9717	36	MACF1
2.210e-02	-3.81	response to stimulus	biological process	GO:0050896	7803	29	18204	50	PITPNC1,ADCY2,CTNND2,CTNNA2,SOX5,GPM6A,DTNA,PARD3,NTRK3,PRKCA,RPS6KA2,RORA,NRXN1,NRG3,FMN2,ATP1A2,DCLK2,NTRK2,SLC1A2,SYNE1,ERBB4,DGKG,GFAP,NDRG2,SORBS1,RYR3,MACF1,TNC,KALRN
2.215e-02	-3.81	Endothelins	Pathway Interaction DB	endothelinpathway	53	2	2226	10	PRKCA,ADCY2
2.224e-02	-3.81	glial cell differentiation	biological process	GO:0010001	219	3	18204	50	NTRK2,GFAP,PARD3
2.226e-02	-3.80	Glioma	KEGG pathways	ko05214	64	2	7161	26	PRKCA,CAMK2G
2.226e-02	-3.80	Glioma	KEGG pathways	hsa05214	64	2	7161	26	CAMK2G,PRKCA
2.233e-02	-3.80	regulation of sodium ion transport	biological process	GO:0002028	84	2	18204	50	NKAIN3,ATP1A2
2.233e-02	-3.80	stem cell development	biological process	GO:0048864	84	2	18204	50	ERBB4,MSI2
2.233e-02	-3.80	peripheral nervous system development	biological process	GO:0007422	84	2	18204	50	NTRK2,PARD3
2.246e-02	-3.80	CTDSPL (CTD small phosphatase like)	protein interactions	10217	90	2	19454	50	FMN2,DTNA
2.250e-02	-3.79	response to mechanical stimulus	biological process	GO:0009612	220	3	18204	50	ATP1A2,NRXN1,TNC
2.272e-02	-3.78	human chr6q25.2	chromosome location	human chr6q25.2	12	1	26134	50	SYNE1
2.290e-02	-3.78	MUC4 (mucin 4, cell surface associated)	protein interactions	4585	9	1	19454	50	ERBB4
2.290e-02	-3.78	LSB3 (Lsb3p)	protein interactions	850580	9	1	19454	50	GFAP
2.290e-02	-3.78	MMP19 (matrix metallopeptidase 19)	protein interactions	4327	9	1	19454	50	SYNE1
2.290e-02	-3.78	CAMK2N1 (calcium/calmodulin dependent protein kinase II inhibitor 1)	protein interactions	55450	9	1	19454	50	CAMK2G
2.290e-02	-3.78	Tyw3 (tRNA-yW synthesizing protein 3 homolog (S. cerevisiae))	protein interactions	209584	9	1	19454	50	CTNNA2
2.290e-02	-3.78	NRXN2 (neurexin 2)	protein interactions	9379	9	1	19454	50	MACF1
2.290e-02	-3.78	SCTR (secretin receptor)	protein interactions	6344	9	1	19454	50	PRKCA
2.292e-02	-3.78	PTPN21 (protein tyrosine phosphatase non-receptor type 21)	protein interactions	11099	91	2	19454	50	NRG3,ERBB4
2.292e-02	-3.78	THUMPD3 (THUMP domain containing 3)	protein interactions	25917	91	2	19454	50	RPS6KA2,CTNND2
2.292e-02	-3.78	DGUOK (deoxyguanosine kinase)	protein interactions	1716	91	2	19454	50	GPM6A,NTM
2.299e-02	-3.77	CLU (clusterin)	protein interactions	1191	237	3	19454	50	LRP1B,NTRK3,TNC
2.306e-02	-3.77	stomach-carcinoma-papillary_adenocarcinoma	COSMIC cancer mutations	stomach-carcinoma-papillary_adenocarcinoma	8	1	16828	49	NTRK3
2.306e-02	-3.77	papillary_adenocarcinoma	COSMIC cancer mutations	papillary_adenocarcinoma	8	1	16828	49	NTRK3
2.311e-02	-3.77	Release of Hh-Np from the secreting cell	REACTOME pathways	R-HSA-5362798	8	1	10285	30	GPC5
2.311e-02	-3.77	Downregulation of ERBB4 signaling	REACTOME pathways	R-HSA-1253288	8	1	10285	30	ERBB4
2.311e-02	-3.77	HuR (ELAVL1) binds and stabilizes mRNA	REACTOME pathways	R-HSA-450520	8	1	10285	30	PRKCA
2.318e-02	-3.76	skin-leg-malignant_melanoma-superficial_spreading	COSMIC cancer mutations	skin-leg-malignant_melanoma-superficial_spreading	210	3	16828	49	NTM,SLC4A4,LRP1B
2.331e-02	-3.76	Immunoglobulins	gene3d domains	2.60.40.10	721	6	14470	45	NTRK2,LSAMP,NTRK3,NTM,TNC,KALRN
2.331e-02	-3.76	flotillin complex	cellular component	GO:0016600	9	1	19108	50	SORBS1
2.331e-02	-3.76	astrocyte end-foot	cellular component	GO:0097450	9	1	19108	50	GFAP
2.332e-02	-3.76	NA_DICARBOXYL_SYMP_1	prosite domains	PS00713	7	1	12186	41	SLC1A2
2.332e-02	-3.76	NA_DICARBOXYL_SYMP_2	prosite domains	PS00714	7	1	12186	41	SLC1A2
2.333e-02	-3.76	small molecule binding	molecular function	GO:0036094	6197	24	18094	49	NAV2,RYR3,ATP1A2,SLC1A2,RPS6KA2,NTRK2,CAMK2G,PARD3,DCLK2,DGKG,ERBB4,KALRN,MACF1,NRXN1,RORA,DTNA,NTRK3,ABLIM1,GLIS3,PRKCA,LRP1B,ADCY2,MGAT4C,PITPNC1
2.334e-02	-3.76	central nervous system neuron development	biological process	GO:0021954	86	2	18204	50	DCLK2,NTRK2
2.334e-02	-3.76	protein localization to cell junction	biological process	GO:1902414	86	2	18204	50	NRXN1,ERBB4
2.361e-02	-3.75	regulation of biological quality	biological process	GO:0065008	2936	14	18204	50	ATP1A2,NRXN1,MACF1,PRKCA,GPM6A,CAMK2G,ERBB4,GFAP,DGKG,SLC4A4,SYNE1,NAV2,CTNNA2,NTRK2
2.371e-02	-3.74	LIM_DOMAIN_1	prosite domains	PS00478	71	2	12186	41	ABLIM1,NEBL
2.371e-02	-3.74	LIM_DOMAIN_2	prosite domains	PS50023	71	2	12186	41	ABLIM1,NEBL
2.380e-02	-3.74	bone-fibula-Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour	COSMIC cancer mutations	bone-fibula-Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour	377	4	16828	49	NRXN1,SYNE1,TRPM3,MACF1
2.387e-02	-3.74	EDTRNSPORT	prints domains	PR00173	7	1	5227	18	SLC1A2
2.398e-02	-3.73	C1	smart domains	SM00109	65	2	9717	36	PRKCA,DGKG
2.404e-02	-3.73	Band3_cytoplasmic_dom	interpro domains	IPR013769	9	1	18521	50	SLC4A4
2.404e-02	-3.73	DNA-bd_RFX	interpro domains	IPR003150	9	1	18521	50	RFX4
2.404e-02	-3.73	Doublecortin_dom	interpro domains	IPR003533	9	1	18521	50	DCLK2
2.412e-02	-3.72	calcium-dependent protein serine/threonine kinase activity	molecular function	GO:0009931	9	1	18094	49	PRKCA
2.427e-02	-3.72	DSG2 (desmoglein 2)	protein interactions	1829	242	3	19454	50	PARD3,NTRK3,RPS6KA2
2.435e-02	-3.72	WWC1 (WW and C2 domain containing 1)	protein interactions	23286	94	2	19454	50	ABLIM1,PRKCA
2.436e-02	-3.71	positive regulation of peptidyl-serine phosphorylation	biological process	GO:0033138	88	2	18204	50	NTRK3,NTRK2
2.446e-02	-3.71	release of sequestered calcium ion into cytosol by sarcoplasmic reticulum	biological process	GO:0014808	9	1	18204	50	RYR3
2.446e-02	-3.71	mesenchymal-epithelial cell signaling	biological process	GO:0060638	9	1	18204	50	TNC
2.446e-02	-3.71	negative regulation of actin nucleation	biological process	GO:0051126	9	1	18204	50	CTNNA2
2.446e-02	-3.71	hindbrain radial glia guided cell migration	biological process	GO:0021932	9	1	18204	50	CTNNA2
2.446e-02	-3.71	positive regulation of synapse maturation	biological process	GO:0090129	9	1	18204	50	NRXN1
2.446e-02	-3.71	negative regulation of striated muscle contraction	biological process	GO:0045988	9	1	18204	50	ATP1A2
2.452e-02	-3.71	Band_3_cyto	pfam domains	PF07565	9	1	17795	49	SLC4A4
2.452e-02	-3.71	RFX_DNA_binding	pfam domains	PF02257	9	1	17795	49	RFX4
2.458e-02	-3.71	Neurotrophic factor-mediated Trk receptor signaling	Pathway Interaction DB	trkrpathway	56	2	2226	10	NTRK3,NTRK2
2.461e-02	-3.70	myofibril	cellular component	GO:0030016	239	3	19108	50	RYR3,NEBL,SYNE1
2.462e-02	-3.70	Villin headpiece domain	gene3d domains	1.10.950.10	8	1	14470	45	ABLIM1
2.483e-02	-3.70	MPP7 (MAGUK p55 scaffold protein 7)	protein interactions	143098	95	2	19454	50	RPS6KA2,NTRK3
2.494e-02	-3.69	Amphetamine addiction	KEGG pathways	ko05031	68	2	7161	26	PRKCA,CAMK2G
2.494e-02	-3.69	Amphetamine addiction	KEGG pathways	hsa05031	68	2	7161	26	CAMK2G,PRKCA
2.501e-02	-3.69	regulation of cell migration	biological process	GO:0030334	1061	7	18204	50	ERBB4,TNC,NRG3,NTRK3,PRKCA,CTNNA2,MACF1
2.514e-02	-3.68	intermediate filament cytoskeleton	cellular component	GO:0045111	241	3	19108	50	GFAP,MACF1,DTNA
2.528e-02	-3.68	Opioid Signalling	REACTOME pathways	R-HSA-111885	85	2	10285	30	ADCY2,PRKCA
2.532e-02	-3.68	SOCS2 (suppressor of cytokine signaling 2)	protein interactions	8835	96	2	19454	50	NTRK2,ERBB4
2.534e-02	-3.68	Vasopressin Regulation of Water Homeostasis	SMPDB pathways	SMP0000322	7	1	1369	5	ADCY2
2.541e-02	-3.67	EREG (epiregulin)	protein interactions	2069	10	1	19454	50	ERBB4
2.541e-02	-3.67	DOA4 (ubiquitin-specific protease DOA4)	protein interactions	851641	10	1	19454	50	NAV2
2.541e-02	-3.67	CALB2 (calbindin 2)	protein interactions	794	10	1	19454	50	GPM6A
2.541e-02	-3.67	TNP1 (transition protein 1)	protein interactions	7141	10	1	19454	50	PRKCA
2.541e-02	-3.67	SLC8A2 (solute carrier family 8 member A2)	protein interactions	6543	10	1	19454	50	GPM6A
2.541e-02	-3.67	CHRDL1 (chordin like 1)	protein interactions	91851	10	1	19454	50	LRP1B
2.541e-02	-3.67	AXDND1 (axonemal dynein light chain domain containing 1)	protein interactions	126859	10	1	19454	50	SYNE1
2.541e-02	-3.67	GSG1 (germ cell associated 1)	protein interactions	83445	10	1	19454	50	PITPNC1
2.541e-02	-3.67	PPY (pancreatic polypeptide)	protein interactions	5539	10	1	19454	50	PRKCA
2.541e-02	-3.67	PTPRT (protein tyrosine phosphatase receptor type T)	protein interactions	11122	10	1	19454	50	ERBB4
2.541e-02	-3.67	Vbp1 (von Hippel-Lindau binding protein 1)	protein interactions	22327	10	1	19454	50	ABLIM1
2.541e-02	-3.67	ZNF563 (zinc finger protein 563)	protein interactions	147837	10	1	19454	50	LRP1B
2.541e-02	-3.67	Smurf2 (SMAD specific E3 ubiquitin protein ligase 2)	protein interactions	66313	10	1	19454	50	GLIS3
2.544e-02	-3.67	cell leading edge	cellular component	GO:0031252	428	4	19108	50	SLC1A2,MACF1,ABLIM1,PSD2
2.546e-02	-3.67	regulation of biological process	biological process	GO:0050789	12079	40	18204	50	ERBB4,CAMK2G,SLC4A4,DGKG,GLIS3,GFAP,PSD2,SYNE1,HPSE2,MSI2,SFXN5,NTRK2,SLC1A2,TNC,GPC5,KALRN,NKAIN3,RYR3,MACF1,NDRG2,SORBS1,PARD3,DTNA,GPM6A,NTRK3,SOX5,CTNND2,CTNNA2,PITPNC1,NPAS3,ADCY2,NRG3,FMN2,ATP1A2,DCLK2,RORA,NRXN1,RFX4,RPS6KA2,PRKCA
2.566e-02	-3.66	PLEC	smart domains	SM00250	7	1	9717	36	MACF1
2.568e-02	-3.66	spindle	COSMIC cancer mutations	spindle	386	4	16828	49	MACF1,CTNND2,TRPM3,KALRN
2.579e-02	-3.66	biological regulation	biological process	GO:0065007	12501	41	18204	50	KALRN,TNC,GPC5,RYR3,MACF1,NKAIN3,SORBS1,NDRG2,SLC4A4,DGKG,GFAP,GLIS3,ERBB4,CAMK2G,SYNE1,NAV2,PSD2,SFXN5,MSI2,HPSE2,SLC1A2,NTRK2,FMN2,ATP1A2,DCLK2,NRG3,RORA,NRXN1,RPS6KA2,RFX4,PRKCA,DTNA,GPM6A,PARD3,NTRK3,SOX5,CTNNA2,CTNND2,NPAS3,ADCY2,PITPNC1
2.581e-02	-3.66	STXBP3 (syntaxin binding protein 3)	protein interactions	6814	97	2	19454	50	RPS6KA2,PRKCA
2.581e-02	-3.66	BTG3 (BTG anti-proliferation factor 3)	protein interactions	10950	97	2	19454	50	SYNE1,DCLK2
2.581e-02	-3.66	LIN7C (lin-7 homolog C, crumbs cell polarity complex component)	protein interactions	55327	97	2	19454	50	NTRK3,ABLIM1
2.581e-02	-3.66	PLCB3 (phospholipase C beta 3)	protein interactions	5331	97	2	19454	50	CAMK2G,PARD3
2.585e-02	-3.66	ABL1 (ABL proto-oncogene 1, non-receptor tyrosine kinase)	protein interactions	25	248	3	19454	50	ERBB4,CTNND2,SORBS1
2.589e-02	-3.65	fibula	COSMIC cancer mutations	fibula	387	4	16828	49	MACF1,SYNE1,TRPM3,NRXN1
2.596e-02	-3.65	EGFR Transactivation by Gastrin	REACTOME pathways	R-HSA-2179392	9	1	10285	30	PRKCA
2.612e-02	-3.65	GAN (gigaxonin)	protein interactions	8139	249	3	19454	50	CTNNA2,SYNE1,GFAP
2.612e-02	-3.65	MYO1B (myosin IB)	protein interactions	4430	249	3	19454	50	CAMK2G,PARD3,NTRK3
2.617e-02	-3.64	sarcoplasm	cellular component	GO:0016528	96	2	19108	50	CAMK2G,RYR3
2.621e-02	-3.64	oesophagus-carcinoma-adenocarcinoma	COSMIC cancer mutations	oesophagus-carcinoma-adenocarcinoma	13112	44	16828	49	ATP1A2,TNC,PSD2,CTNND2,SOX5,CAMK2G,NTRK2,LSAMP,NRXN1,NPAS3,SLC4A4,ERBB4,NDRG2,GPC5,CDH20,LRP1B,ADCY2,PARD3,SYNE1,SLC1A2,SORBS1,HPSE2,MGAT4C,RORA,KALRN,DCLK2,MACF1,NAV2,GPM6A,NKAIN3,TRPM3,SFXN5,GLIS3,GFAP,NRG3,RFX4,NEBL,NTM,PRKCA,RYR3,NTRK3,RPS6KA2,DGKG,FMN2
2.631e-02	-3.64	MB21D2 (Mab-21 domain containing 2)	protein interactions	151963	98	2	19454	50	NTRK3,NTRK2
2.631e-02	-3.64	FRAS1 (Fraser extracellular matrix complex subunit 1)	protein interactions	80144	98	2	19454	50	MGAT4C,HPSE2
2.631e-02	-3.64	DNAAF2 (dynein axonemal assembly factor 2)	protein interactions	55172	98	2	19454	50	GPM6A,LSAMP
2.639e-02	-3.63	PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling	REACTOME pathways	R-HSA-6811558	87	2	10285	30	NRG3,ERBB4
2.645e-02	-3.63	protein tetramerization	biological process	GO:0051262	92	2	18204	50	RYR3,TRPM3
2.646e-02	-3.63	human chr2p16.3	chromosome location	human chr2p16.3	14	1	26134	50	NRXN1
2.646e-02	-3.63	human chr2p13.2	chromosome location	human chr2p13.2	14	1	26134	50	SFXN5
2.646e-02	-3.63	human chr9q33.1	chromosome location	human chr9q33.1	14	1	26134	50	TNC
2.654e-02	-3.63	upper_arm	COSMIC cancer mutations	upper_arm	582	5	16828	49	LRP1B,FMN2,ERBB4,SLC4A4,SYNE1
2.661e-02	-3.63	HP	prosite domains	PS51089	8	1	12186	41	ABLIM1
2.668e-02	-3.62	HCO3_transpt-like_TM_dom	interpro domains	IPR011531	10	1	18521	50	SLC4A4
2.668e-02	-3.62	Diacylglycerol_kin_accessory	interpro domains	IPR000756	10	1	18521	50	DGKG
2.668e-02	-3.62	HCO3_transpt_euk	interpro domains	IPR003020	10	1	18521	50	SLC4A4
2.668e-02	-3.62	DGK	interpro domains	IPR037607	10	1	18521	50	DGKG
2.668e-02	-3.62	MIR_motif	interpro domains	IPR016093	10	1	18521	50	RYR3
2.668e-02	-3.62	PTrfase/Anion_transptr	interpro domains	IPR016152	10	1	18521	50	SLC4A4
2.668e-02	-3.62	PAS_fold_3	interpro domains	IPR013655	10	1	18521	50	NPAS3
2.668e-02	-3.62	Doublecortin_dom_sf	interpro domains	IPR036572	10	1	18521	50	DCLK2
2.668e-02	-3.62	MIR_dom_sf	interpro domains	IPR036300	10	1	18521	50	RYR3
2.676e-02	-3.62	phosphatidylinositol transfer activity	molecular function	GO:0008526	10	1	18094	49	PITPNC1
2.676e-02	-3.62	calcium-dependent protein kinase activity	molecular function	GO:0010857	10	1	18094	49	PRKCA
2.676e-02	-3.62	inorganic cation transmembrane transport	biological process	GO:0098662	618	5	18204	50	RYR3,GPM6A,ATP1A2,TRPM3,SLC4A4
2.678e-02	-3.62	YWHAE (tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein epsilon)	protein interactions	7531	1150	7	19454	50	ABLIM1,DCLK2,NAV2,MACF1,CAMK2G,SORBS1,PARD3
2.678e-02	-3.62	HSP90AA1 (heat shock protein 90 alpha family class A member 1)	protein interactions	3320	1150	7	19454	50	DCLK2,NTRK3,NTRK2,PRKCA,ERBB4,CAMK2G,RPS6KA2
2.690e-02	-3.62	chemical synaptic transmission	biological process	GO:0007268	415	4	18204	50	NRXN1,SLC1A2,RPS6KA2,DTNA
2.690e-02	-3.62	anterograde trans-synaptic signaling	biological process	GO:0098916	415	4	18204	50	NRXN1,SLC1A2,DTNA,RPS6KA2
2.693e-02	-3.61	behavior	biological process	GO:0007610	619	5	18204	50	NAV2,ATP1A2,SLC1A2,NTRK2,NRXN1
2.699e-02	-3.61	intermediate filament cytoskeleton organization	biological process	GO:0045104	93	2	18204	50	MACF1,GFAP
2.714e-02	-3.61	mitochondrial fragmentation involved in apoptotic process	biological process	GO:0043653	10	1	18204	50	ERBB4
2.714e-02	-3.61	desmosome organization	biological process	GO:0002934	10	1	18204	50	PRKCA
2.714e-02	-3.61	learned vocalization behavior or vocal learning	biological process	GO:0098598	10	1	18204	50	NRXN1
2.714e-02	-3.61	urea transmembrane transport	biological process	GO:0071918	10	1	18204	50	SLC14A1
2.714e-02	-3.61	substrate-independent telencephalic tangential migration	biological process	GO:0021826	10	1	18204	50	NRG3
2.714e-02	-3.61	negative regulation of glial cell apoptotic process	biological process	GO:0034351	10	1	18204	50	PRKCA
2.714e-02	-3.61	postsynaptic membrane assembly	biological process	GO:0097104	10	1	18204	50	NRXN1
2.714e-02	-3.61	trans-synaptic signaling, modulating synaptic transmission	biological process	GO:0099550	10	1	18204	50	NTRK2
2.714e-02	-3.61	substrate-independent telencephalic tangential interneuron migration	biological process	GO:0021843	10	1	18204	50	NRG3
2.714e-02	-3.61	cAMP biosynthetic process	biological process	GO:0006171	10	1	18204	50	ADCY2
2.714e-02	-3.61	cellular response to cocaine	biological process	GO:0071314	10	1	18204	50	SLC1A2
2.714e-02	-3.61	release of sequestered calcium ion into cytosol by endoplasmic reticulum	biological process	GO:1903514	10	1	18204	50	RYR3
2.714e-02	-3.61	cellular response to brain-derived neurotrophic factor stimulus	biological process	GO:1990416	10	1	18204	50	NTRK2
2.714e-02	-3.61	positive regulation of lipopolysaccharide-mediated signaling pathway	biological process	GO:0031666	10	1	18204	50	PRKCA
2.714e-02	-3.61	retinal rod cell development	biological process	GO:0046548	10	1	18204	50	NTRK2
2.714e-02	-3.61	establishment of centrosome localization	biological process	GO:0051660	10	1	18204	50	PARD3
2.714e-02	-3.61	postsynaptic density assembly	biological process	GO:0097107	10	1	18204	50	NRXN1
2.714e-02	-3.61	regulation of mesenchymal stem cell differentiation	biological process	GO:2000739	10	1	18204	50	SOX5
2.719e-02	-3.60	EGF-type_Asp/Asn_hydroxyl_site	interpro domains	IPR000152	95	2	18521	50	LRP1B,NRXN1
2.719e-02	-3.60	response to organic cyclic compound	biological process	GO:0014070	843	6	18204	50	TNC,RORA,ATP1A2,SLC1A2,ADCY2,RYR3
2.720e-02	-3.60	DAGK_acc	pfam domains	PF00609	10	1	17795	49	DGKG
2.720e-02	-3.60	MIR	pfam domains	PF02815	10	1	17795	49	RYR3
2.720e-02	-3.60	PAS_3	pfam domains	PF08447	10	1	17795	49	NPAS3
2.720e-02	-3.60	HCO3_cotransp	pfam domains	PF00955	10	1	17795	49	SLC4A4
2.721e-02	-3.60	PRKAA1 (protein kinase AMP-activated catalytic subunit alpha 1)	protein interactions	5562	253	3	19454	50	RPS6KA2,NTRK3,SLC4A4
2.731e-02	-3.60	APBA1 (amyloid beta precursor protein binding family A member 1)	protein interactions	320	100	2	19454	50	ABLIM1,NRXN1
2.731e-02	-3.60	ATP4A (ATPase H+/K+ transporting subunit alpha)	protein interactions	495	100	2	19454	50	ATP1A2,GPM6A
2.731e-02	-3.60	NDFIP1 (Nedd4 family interacting protein 1)	protein interactions	80762	100	2	19454	50	NTRK3,NTRK2
2.734e-02	-3.60	contractile muscle fiber	cellular component	GO:0043292	249	3	19108	50	RYR3,SYNE1,NEBL
2.752e-02	-3.59	intermediate filament-based process	biological process	GO:0045103	94	2	18204	50	MACF1,GFAP
2.756e-02	-3.59	muscle contraction	biological process	GO:0006936	238	3	18204	50	ATP1A2,RYR3,DTNA
2.765e-02	-3.59	Doublecortin domain	gene3d domains	3.10.20.230	9	1	14470	45	DCLK2
2.781e-02	-3.58	MYLK (myosin light chain kinase)	protein interactions	4638	101	2	19454	50	CAMK2G,PRKCA
2.781e-02	-3.58	FAM171A2 (family with sequence similarity 171 member A2)	protein interactions	284069	101	2	19454	50	NTRK3,NTRK2
2.792e-02	-3.58	Batf3 (basic leucine zipper transcription factor, ATF-like 3)	protein interactions	381319	11	1	19454	50	MACF1
2.792e-02	-3.58	SYTL1 (synaptotagmin like 1)	protein interactions	84958	11	1	19454	50	NRXN1
2.792e-02	-3.58	Cobll1 (Cobl-like 1)	protein interactions	319876	11	1	19454	50	ABLIM1
2.792e-02	-3.58	SYN3 (synapsin III)	protein interactions	8224	11	1	19454	50	GPM6A
2.792e-02	-3.58	Wipi2 (WD repeat domain, phosphoinositide interacting 2)	protein interactions	74781	11	1	19454	50	MACF1
2.792e-02	-3.58	TMEM53 (transmembrane protein 53)	protein interactions	79639	11	1	19454	50	PRKCA
2.792e-02	-3.58	ITPKA (inositol-trisphosphate 3-kinase A)	protein interactions	3706	11	1	19454	50	PRKCA
2.792e-02	-3.58	AQP5 (aquaporin 5)	protein interactions	362	11	1	19454	50	ATP1A2
2.795e-02	-3.58	lipid binding	molecular function	GO:0008289	861	6	18094	49	PSD2,PARD3,DGKG,PITPNC1,RORA,ATP1A2
2.804e-02	-3.57	ovary-other-neoplasm	COSMIC cancer mutations	ovary-other-neoplasm	12717	43	16828	49	ATP1A2,PSD2,SLC4A4,ERBB4,NDRG2,ADCY2,GPC5,LRP1B,PARD3,MSI2,SYNE1,MGAT4C,KALRN,DCLK2,NKAIN3,GLIS3,SFXN5,NRG3,RYR3,NTM,PRKCA,DGKG,FMN2,RPS6KA2,TNC,CTNND2,SOX5,NTRK2,LSAMP,CDH20,SORBS1,SLC1A2,HPSE2,ABLIM1,RORA,GPM6A,NAV2,MACF1,GFAP,TRPM3,NEBL,RFX4,NTRK3
2.807e-02	-3.57	cardiac muscle cell differentiation	biological process	GO:0055007	95	2	18204	50	SYNE1,NEBL
2.811e-02	-3.57	PI3K/AKT Signaling in Cancer	REACTOME pathways	R-HSA-2219528	90	2	10285	30	ERBB4,NRG3
2.826e-02	-3.57	LIM	smart domains	SM00132	71	2	9717	36	NEBL,ABLIM1
2.831e-02	-3.56	ankle	COSMIC cancer mutations	ankle	398	4	16828	49	ERBB4,NRG3,KALRN,PARD3
2.832e-02	-3.56	human chr8q12.3	chromosome location	human chr8q12.3	15	1	26134	50	NKAIN3
2.832e-02	-3.56	human chr10p12.31	chromosome location	human chr10p12.31	15	1	26134	50	NEBL
2.832e-02	-3.56	human chr18q12.3	chromosome location	human chr18q12.3	15	1	26134	50	SLC14A1
2.832e-02	-3.56	GRAP2 (GRB2 related adaptor protein 2)	protein interactions	9402	102	2	19454	50	GFAP,ERBB4
2.832e-02	-3.56	KRTAP6-1 (keratin associated protein 6-1)	protein interactions	337966	102	2	19454	50	CAMK2G,GLIS3
2.842e-02	-3.56	perisynaptic extracellular matrix	cellular component	GO:0098966	11	1	19108	50	TNC
2.842e-02	-3.56	nuclear membrane microtubule tethering complex	cellular component	GO:0106094	11	1	19108	50	SYNE1
2.842e-02	-3.56	nuclear membrane protein complex	cellular component	GO:0106083	11	1	19108	50	SYNE1
2.842e-02	-3.56	meiotic nuclear membrane microtubule tethering complex	cellular component	GO:0034993	11	1	19108	50	SYNE1
2.842e-02	-3.56	microtubule organizing center attachment site	cellular component	GO:0034992	11	1	19108	50	SYNE1
2.860e-02	-3.55	PLCG1 (phospholipase C gamma 1)	protein interactions	5335	258	3	19454	50	NTRK3,NTRK2,ERBB4
2.862e-02	-3.55	regulation of muscle adaptation	biological process	GO:0043502	96	2	18204	50	PRKCA,CAMK2G
2.865e-02	-3.55	HER-positive_carcinoma	COSMIC cancer mutations	HER-positive_carcinoma	2025	11	16828	49	RORA,NTRK2,ABLIM1,TNC,MSI2,NTRK3,PRKCA,RPS6KA2,GPC5,ERBB4,NRG3
2.865e-02	-3.55	breast-carcinoma-HER-positive_carcinoma	COSMIC cancer mutations	breast-carcinoma-HER-positive_carcinoma	2025	11	16828	49	TNC,MSI2,ERBB4,NRG3,ABLIM1,GPC5,PRKCA,RORA,NTRK3,NTRK2,RPS6KA2
2.875e-02	-3.55	ruffle membrane	cellular component	GO:0032587	101	2	19108	50	PSD2,MACF1
2.876e-02	-3.55	metal ion transport	biological process	GO:0030001	630	5	18204	50	SLC4A4,TRPM3,ATP1A2,RYR3,GPM6A
2.880e-02	-3.55	Bicarbonate transporters	REACTOME pathways	R-HSA-425381	10	1	10285	30	SLC4A4
2.880e-02	-3.55	Adenylate cyclase activating pathway	REACTOME pathways	R-HSA-170660	10	1	10285	30	ADCY2
2.880e-02	-3.55	Acetylcholine regulates insulin secretion	REACTOME pathways	R-HSA-399997	10	1	10285	30	PRKCA
2.881e-02	-3.55	upper_aerodigestive_tract-head_neck-carcinoma-squamous_cell_carcinoma	COSMIC cancer mutations	upper_aerodigestive_tract-head_neck-carcinoma-squamous_cell_carcinoma	9263	34	16828	49	ADCY2,CDH20,GPC5,LRP1B,ERBB4,SLC4A4,LSAMP,CAMK2G,NTRK2,SOX5,CTNND2,TNC,ATP1A2,FMN2,DGKG,RPS6KA2,RYR3,NTRK3,PRKCA,NEBL,GLIS3,TRPM3,NKAIN3,NAV2,MACF1,DCLK2,KALRN,RORA,MGAT4C,HPSE2,PITPNC1,SORBS1,SYNE1,MSI2
2.884e-02	-3.55	ZDHHC5 (zinc finger DHHC-type palmitoyltransferase 5)	protein interactions	25921	103	2	19454	50	PARD3,NTRK2
2.884e-02	-3.55	PLEKHA1 (pleckstrin homology domain containing A1)	protein interactions	59338	103	2	19454	50	PARD3,NTRK3
2.885e-02	-3.55	adrenal_gland-adrenal_gland-adrenal_cortical_adenoma-aldosterone_producing	COSMIC cancer mutations	adrenal_gland-adrenal_gland-adrenal_cortical_adenoma-aldosterone_producing	91	2	16828	49	LRP1B,ADCY2
2.889e-02	-3.54	Signaling by GPCR	REACTOME pathways	R-HSA-372790	1299	8	10285	30	RPS6KA2,KALRN,ERBB4,NRG3,CAMK2G,ADCY2,PRKCA,DGKG
2.892e-02	-3.54	Intracellular Signalling Through Prostacyclin Receptor and Prostacyclin	SMPDB pathways	SMP0000354	8	1	1369	5	ADCY2
2.917e-02	-3.53	amino acid transmembrane transport	biological process	GO:0003333	97	2	18204	50	SLC1A2,GFAP
2.927e-02	-3.53	VHP	smart domains	SM00153	8	1	9717	36	ABLIM1
2.927e-02	-3.53	Post-translational modification: synthesis of GPI-anchored proteins	REACTOME pathways	R-HSA-163125	92	2	10285	30	LSAMP,NTM
2.929e-02	-3.53	EF-hand_7	pfam domains	PF13499	97	2	17795	49	DGKG,MACF1
2.935e-02	-3.53	tat (Tat)	protein interactions	155871	1718	9	19454	50	RYR3,ADCY2,PRKCA,GFAP,SLC14A1,TNC,CAMK2G,SORBS1,SLC1A2
2.936e-02	-3.53	HUNK (hormonally up-regulated Neu-associated kinase)	protein interactions	30811	104	2	19454	50	SORBS1,ABLIM1
2.936e-02	-3.53	CDH5 (cadherin 5)	protein interactions	1003	104	2	19454	50	PRKCA,CTNNA2
2.940e-02	-3.53	acetylcholine receptor binding	molecular function	GO:0033130	11	1	18094	49	NRXN1
2.940e-02	-3.53	sulfur amino acid transmembrane transporter activity	molecular function	GO:0000099	11	1	18094	49	SLC1A2
2.940e-02	-3.53	ATP-dependent diacylglycerol kinase activity	molecular function	GO:0004143	11	1	18094	49	DGKG
2.940e-02	-3.53	histone H3 kinase activity	molecular function	GO:0140996	11	1	18094	49	PRKCA
2.964e-02	-3.52	basolateral plasma membrane	cellular component	GO:0016323	257	3	19108	50	SLC4A4,ERBB4,SLC14A1
2.971e-02	-3.52	response to abiotic stimulus	biological process	GO:0009628	1100	7	18204	50	SLC1A2,SYNE1,RORA,NRXN1,TNC,FMN2,ATP1A2
2.980e-02	-3.51	monoatomic cation transmembrane transport	biological process	GO:0098655	636	5	18204	50	TRPM3,SLC4A4,GPM6A,RYR3,ATP1A2
2.981e-02	-3.51	glutamate secretion	biological process	GO:0014047	11	1	18204	50	NTRK2
2.981e-02	-3.51	regulation of Schwann cell proliferation	biological process	GO:0010624	11	1	18204	50	GFAP
2.981e-02	-3.51	L-ascorbic acid metabolic process	biological process	GO:0019852	11	1	18204	50	ATP1A2
2.981e-02	-3.51	ectodermal placode morphogenesis	biological process	GO:0071697	11	1	18204	50	NRG3
2.981e-02	-3.51	cellular response to caffeine	biological process	GO:0071313	11	1	18204	50	RYR3
2.981e-02	-3.51	ectodermal placode formation	biological process	GO:0060788	11	1	18204	50	NRG3
2.981e-02	-3.51	lactone metabolic process	biological process	GO:1901334	11	1	18204	50	ATP1A2
2.981e-02	-3.51	pyramidal neuron development	biological process	GO:0021860	11	1	18204	50	DCLK2
2.981e-02	-3.51	Bergmann glial cell differentiation	biological process	GO:0060020	11	1	18204	50	GFAP
2.981e-02	-3.51	negative regulation of mesenchymal cell apoptotic process	biological process	GO:2001054	11	1	18204	50	SYNE1
2.981e-02	-3.51	L-glutamate import across plasma membrane	biological process	GO:0098712	11	1	18204	50	SLC1A2
2.981e-02	-3.51	L-aspartate transmembrane transport	biological process	GO:0070778	11	1	18204	50	SLC1A2
2.981e-02	-3.51	negative regulation of excitatory postsynaptic potential	biological process	GO:0090394	11	1	18204	50	SYNE1
2.981e-02	-3.51	lipid phosphorylation	biological process	GO:0046834	11	1	18204	50	DGKG
2.981e-02	-3.51	negative regulation of neuron migration	biological process	GO:2001223	11	1	18204	50	NRG3
2.981e-02	-3.51	establishment or maintenance of transmembrane electrochemical gradient	biological process	GO:0010248	11	1	18204	50	ATP1A2
2.988e-02	-3.51	GLB1 (galactosidase beta 1)	protein interactions	2720	105	2	19454	50	SFXN5,RPS6KA2
2.989e-02	-3.51	DC	prosite domains	PS50309	9	1	12186	41	DCLK2
2.989e-02	-3.51	RFX_DBD	prosite domains	PS51526	9	1	12186	41	RFX4
2.999e-02	-3.51	positive regulation of neurogenesis	biological process	GO:0050769	246	3	18204	50	GFAP,NTRK2,MACF1
3.003e-02	-3.51	aldosterone_producing	COSMIC cancer mutations	aldosterone_producing	93	2	16828	49	ADCY2,LRP1B
3.019e-02	-3.50	EGF	smart domains	SM00181	184	3	9717	36	NRXN1,TNC,LRP1B
3.028e-02	-3.50	regulation of neurotransmitter transport	biological process	GO:0051588	99	2	18204	50	ATP1A2,GFAP
3.034e-02	-3.50	response to wounding	biological process	GO:0009611	431	4	18204	50	MACF1,TNC,SLC1A2,DGKG
3.040e-02	-3.49	NSD1 (nuclear receptor binding SET domain protein 1)	protein interactions	64324	106	2	19454	50	NTRK3,RORA
3.042e-02	-3.49	XK (X-linked Kx blood group antigen, Kell and VPS13A binding protein)	protein interactions	7504	12	1	19454	50	PRKCA
3.042e-02	-3.49	PTPN20 (protein tyrosine phosphatase non-receptor type 20)	protein interactions	26095	12	1	19454	50	ERBB4
3.042e-02	-3.49	NTF4 (neurotrophin 4)	protein interactions	4909	12	1	19454	50	NTRK2
3.042e-02	-3.49	INTS4P2 (integrator complex subunit 4 pseudogene 2)	protein interactions	644619	12	1	19454	50	GFAP
3.042e-02	-3.49	MYBPHL (myosin binding protein H like)	protein interactions	343263	12	1	19454	50	GFAP
3.042e-02	-3.49	Ctnnbl1 (catenin, beta like 1)	protein interactions	66642	12	1	19454	50	PRKCA
3.042e-02	-3.49	SMIM20 (small integral membrane protein 20)	protein interactions	389203	12	1	19454	50	ERBB4
3.042e-02	-3.49	CDHR2 (cadherin related family member 2)	protein interactions	54825	12	1	19454	50	RPS6KA2
3.042e-02	-3.49	CA4 (carbonic anhydrase 4)	protein interactions	762	12	1	19454	50	SLC4A4
3.042e-02	-3.49	PROK2 (prokineticin 2)	protein interactions	60675	12	1	19454	50	LRP1B
3.042e-02	-3.49	ART4 (ADP-ribosyltransferase 4 (inactive) (Dombrock blood group))	protein interactions	420	12	1	19454	50	GPM6A
3.042e-02	-3.49	Pard6b (par-6 family cell polarity regulator beta)	protein interactions	58220	12	1	19454	50	PARD3
3.046e-02	-3.49	Negative regulation of the PI3K/AKT network	REACTOME pathways	R-HSA-199418	94	2	10285	30	NRG3,ERBB4
3.059e-02	-3.49	NAKATPASE	prints domains	PR00121	9	1	5227	18	ATP1A2
3.068e-02	-3.48	Helical hairpin bin	gene3d domains	1.10.287.570	10	1	14470	45	SLC4A4
3.085e-02	-3.48	response to alkaloid	biological process	GO:0043279	100	2	18204	50	RYR3,SLC1A2
3.085e-02	-3.48	regulation of dendrite development	biological process	GO:0050773	100	2	18204	50	SYNE1,DGKG
3.093e-02	-3.48	regulation of muscle system process	biological process	GO:0090257	249	3	18204	50	PRKCA,CAMK2G,ATP1A2
3.093e-02	-3.48	APLP2 (amyloid beta precursor like protein 2)	protein interactions	334	107	2	19454	50	PRKCA,HPSE2
3.096e-02	-3.48	sodium:potassium-exchanging ATPase complex	cellular component	GO:0005890	12	1	19108	50	ATP1A2
3.096e-02	-3.48	synapse-associated extracellular matrix	cellular component	GO:0099535	12	1	19108	50	TNC
3.104e-02	-3.47	regulation of cellular component organization	biological process	GO:0051128	2455	12	18204	50	CTNNA2,SYNE1,MACF1,NTRK2,NRG3,GPM6A,NTRK3,TNC,CAMK2G,DGKG,GFAP,NRXN1
3.123e-02	-3.47	haemangiopericytic	COSMIC cancer mutations	haemangiopericytic	95	2	16828	49	RYR3,SYNE1
3.123e-02	-3.47	meninges-meningioma-haemangiopericytic	COSMIC cancer mutations	meninges-meningioma-haemangiopericytic	95	2	16828	49	SYNE1,RYR3
3.142e-02	-3.46	regulation of glucose metabolic process	biological process	GO:0010906	101	2	18204	50	RORA,SORBS1
3.147e-02	-3.46	CLASP1 (cytoplasmic linker associated protein 1)	protein interactions	23332	108	2	19454	50	DCLK2,MACF1
3.147e-02	-3.46	ALDH3B1 (aldehyde dehydrogenase 3 family member B1)	protein interactions	221	108	2	19454	50	GFAP,FMN2
3.149e-02	-3.46	PFN1 (profilin 1)	protein interactions	5216	466	4	19454	50	CAMK2G,MACF1,ABLIM1,FMN2
3.157e-02	-3.46	calcium ion transport	biological process	GO:0006816	251	3	18204	50	TRPM3,RYR3,GPM6A
3.158e-02	-3.46	stomach-carcinoma-tubular_adenocarcinoma	COSMIC cancer mutations	stomach-carcinoma-tubular_adenocarcinoma	11	1	16828	49	NTRK3
3.158e-02	-3.46	tubular_adenocarcinoma	COSMIC cancer mutations	tubular_adenocarcinoma	11	1	16828	49	NTRK3
3.167e-02	-3.45	large_intestine-colon	COSMIC cancer mutations	large_intestine-colon	1291	8	16828	49	SYNE1,ERBB4,TNC,KALRN,NAV2,FMN2,ADCY2,LRP1B
3.177e-02	-3.45	EV release from cardiac cells and their functional effects	WikiPathways	WP3297	9	1	5310	19	ERBB4
3.200e-02	-3.44	PRR20A (proline rich 20A)	protein interactions	122183	109	2	19454	50	SOX5,TRPM3
3.200e-02	-3.44	NOS1AP (nitric oxide synthase 1 adaptor protein)	protein interactions	9722	109	2	19454	50	NTRK2,NTRK3
3.200e-02	-3.44	SIPA1L3 (signal induced proliferation associated 1 like 3)	protein interactions	23094	109	2	19454	50	PARD3,GFAP
3.203e-02	-3.44	adenylate cyclase binding	molecular function	GO:0008179	12	1	18094	49	ADCY2
3.204e-02	-3.44	human chr9q21.33	chromosome location	human chr9q21.33	17	1	26134	50	NTRK2
3.222e-02	-3.44	Heparan sulfate degradation	KEGG pathways	M00078	9	1	7161	26	HPSE2
3.222e-02	-3.44	Heparan sulfate degradation	KEGG pathways	hsa_M00078	9	1	7161	26	HPSE2
3.233e-02	-3.43	SH3DOMAIN	prints domains	PR00452	83	2	5227	18	SORBS1,NEBL
3.248e-02	-3.43	auditory behavior	biological process	GO:0031223	12	1	18204	50	NRXN1
3.248e-02	-3.43	nuclear membrane disassembly	biological process	GO:0051081	12	1	18204	50	PRKCA
3.248e-02	-3.43	sulfur amino acid transport	biological process	GO:0000101	12	1	18204	50	SLC1A2
3.248e-02	-3.43	urea transport	biological process	GO:0015840	12	1	18204	50	SLC14A1
3.248e-02	-3.43	regulation of glial cell apoptotic process	biological process	GO:0034350	12	1	18204	50	PRKCA
3.249e-02	-3.43	Intracellular Signalling Through FSH Receptor and Follicle Stimulating Hormone	SMPDB pathways	SMP0000333	9	1	1369	5	ADCY2
3.249e-02	-3.43	Intracellular Signalling Through Histamine H2 Receptor and Histamine	SMPDB pathways	SMP0000335	9	1	1369	5	ADCY2
3.249e-02	-3.43	Excitatory Neural Signalling Through 5-HTR 7 and Serotonin	SMPDB pathways	SMP0000311	9	1	1369	5	ADCY2
3.249e-02	-3.43	Excitatory Neural Signalling Through 5-HTR 6 and Serotonin	SMPDB pathways	SMP0000312	9	1	1369	5	ADCY2
3.249e-02	-3.43	Excitatory Neural Signalling Through 5-HTR 4 and Serotonin	SMPDB pathways	SMP0000309	9	1	1369	5	ADCY2
3.249e-02	-3.43	Nitric Oxide Signaling Pathway	SMPDB pathways	SMP0063777	9	1	1369	5	PRKCA
3.262e-02	-3.42	regulation of cell motility	biological process	GO:2000145	1122	7	18204	50	NTRK3,NRG3,TNC,ERBB4,CTNNA2,MACF1,PRKCA
3.287e-02	-3.42	DCX	smart domains	SM00537	9	1	9717	36	DCLK2
3.291e-02	-3.41	NCAN (neurocan)	protein interactions	1463	13	1	19454	50	TNC
3.291e-02	-3.41	KCNQ2 (potassium voltage-gated channel subfamily Q member 2)	protein interactions	3785	13	1	19454	50	PRKCA
3.291e-02	-3.41	IL23R (interleukin 23 receptor)	protein interactions	149233	13	1	19454	50	PRKCA
3.291e-02	-3.41	NPR2 (natriuretic peptide receptor 2)	protein interactions	4882	13	1	19454	50	CAMK2G
3.291e-02	-3.41	TBCC (tubulin folding cofactor C)	protein interactions	6903	13	1	19454	50	NTM
3.291e-02	-3.41	MYO16 (myosin XVI)	protein interactions	23026	13	1	19454	50	NRXN1
3.291e-02	-3.41	RAB3C (RAB3C, member RAS oncogene family)	protein interactions	115827	13	1	19454	50	GPM6A
3.291e-02	-3.41	RNASE4 (ribonuclease A family member 4)	protein interactions	6038	13	1	19454	50	LRP1B
3.291e-02	-3.41	JAM2 (junctional adhesion molecule 2)	protein interactions	58494	13	1	19454	50	PARD3
3.315e-02	-3.41	MIR	prosite domains	PS50919	10	1	12186	41	RYR3
3.318e-02	-3.41	protein complex oligomerization	biological process	GO:0051259	256	3	18204	50	SLC1A2,TRPM3,RYR3
3.350e-02	-3.40	cytoplasmic side of lysosomal membrane	cellular component	GO:0098574	13	1	19108	50	GFAP
3.373e-02	-3.39	neural precursor cell proliferation	biological process	GO:0061351	105	2	18204	50	RORA,SOX5
3.373e-02	-3.39	cellular response to alcohol	biological process	GO:0097306	105	2	18204	50	TNC,ADCY2
3.373e-02	-3.39	gland morphogenesis	biological process	GO:0022612	105	2	18204	50	TNC,NRG3
3.373e-02	-3.39	response to interleukin-1	biological process	GO:0070555	105	2	18204	50	RORA,PRKCA
3.377e-02	-3.39	SHC1 events in EGFR signaling	REACTOME pathways	R-HSA-180336	245	3	10285	30	ERBB4,NRG3,CAMK2G
3.377e-02	-3.39	SOS-mediated signalling	REACTOME pathways	R-HSA-112412	245	3	10285	30	NRG3,ERBB4,CAMK2G
3.377e-02	-3.39	GRB2 events in EGFR signaling	REACTOME pathways	R-HSA-179812	245	3	10285	30	CAMK2G,ERBB4,NRG3
3.377e-02	-3.39	RAF/MAP kinase cascade	REACTOME pathways	R-HSA-5673001	245	3	10285	30	NRG3,ERBB4,CAMK2G
3.389e-02	-3.38	human chr18q21.33	chromosome location	human chr18q21.33	18	1	26134	50	CDH20
3.392e-02	-3.38	cAMP signaling pathway	KEGG pathways	ko04024	198	3	7161	26	CAMK2G,ADCY2,ATP1A2
3.392e-02	-3.38	cAMP signaling pathway	KEGG pathways	hsa04024	198	3	7161	26	CAMK2G,ATP1A2,ADCY2
3.394e-02	-3.38	HCO3TRNSPORT	prints domains	PR01231	10	1	5227	18	SLC4A4
3.402e-02	-3.38	steroid binding	molecular function	GO:0005496	107	2	18094	49	ATP1A2,RORA
3.418e-02	-3.38	GFI1B (growth factor independent 1B transcriptional repressor)	protein interactions	8328	113	2	19454	50	KALRN,DTNA
3.418e-02	-3.38	KIRREL1 (kirre like nephrin family adhesion molecule 1)	protein interactions	55243	113	2	19454	50	RPS6KA2,PARD3
3.432e-02	-3.37	cellular response to ketone	biological process	GO:1901655	106	2	18204	50	TNC,ADCY2
3.446e-02	-3.37	Defective EXT2 causes exostoses 2	REACTOME pathways	R-HSA-3656237	12	1	10285	30	GPC5
3.446e-02	-3.37	Defective EXT1 causes exostoses 1, TRPS2 and CHDS	REACTOME pathways	R-HSA-3656253	12	1	10285	30	GPC5
3.451e-02	-3.37	EGF_2	prosite domains	PS01186	213	3	12186	41	TNC,LRP1B,NRG3
3.455e-02	-3.37	distal axon	cellular component	GO:0150034	273	3	19108	50	GPM6A,NDRG2,NTRK2
3.457e-02	-3.36	TJP2 (tight junction protein 2)	protein interactions	9414	278	3	19454	50	NEBL,SORBS1,PARD3
3.465e-02	-3.36	potassium ion binding	molecular function	GO:0030955	13	1	18094	49	ATP1A2
3.465e-02	-3.36	monoatomic cation:bicarbonate symporter activity	molecular function	GO:0140410	13	1	18094	49	SLC4A4
3.475e-02	-3.36	Visual phototransduction	REACTOME pathways	R-HSA-2187338	101	2	10285	30	GPC5,PRKCA
3.500e-02	-3.35	Ion_trans_dom	interpro domains	IPR005821	109	2	18521	50	TRPM3,RYR3
3.505e-02	-3.35	cellular response to stimulus	biological process	GO:0051716	6307	24	18204	50	RORA,DCLK2,ATP1A2,FMN2,NRG3,PRKCA,RPS6KA2,NTRK3,DTNA,PARD3,ADCY2,PITPNC1,CTNND2,KALRN,TNC,SORBS1,NDRG2,MACF1,RYR3,GFAP,DGKG,ERBB4,SLC1A2,NTRK2
3.514e-02	-3.35	membrane disassembly	biological process	GO:0030397	13	1	18204	50	PRKCA
3.514e-02	-3.35	cellular response to vitamin D	biological process	GO:0071305	13	1	18204	50	TNC
3.514e-02	-3.35	cerebellar Purkinje cell differentiation	biological process	GO:0021702	13	1	18204	50	RORA
3.514e-02	-3.35	regulation of respiratory gaseous exchange by nervous system process	biological process	GO:0002087	13	1	18204	50	ATP1A2
3.514e-02	-3.35	T-helper 17 cell differentiation	biological process	GO:0072539	13	1	18204	50	RORA
3.514e-02	-3.35	nervous system process involved in regulation of systemic arterial blood pressure	biological process	GO:0001976	13	1	18204	50	NAV2
3.514e-02	-3.35	ectodermal placode development	biological process	GO:0071696	13	1	18204	50	NRG3
3.514e-02	-3.35	postsynaptic specialization assembly	biological process	GO:0098698	13	1	18204	50	NRXN1
3.514e-02	-3.35	prepulse inhibition	biological process	GO:0060134	13	1	18204	50	CTNNA2
3.514e-02	-3.35	negative regulation of cytosolic calcium ion concentration	biological process	GO:0051481	13	1	18204	50	ATP1A2
3.514e-02	-3.35	olfactory bulb interneuron differentiation	biological process	GO:0021889	13	1	18204	50	ERBB4
3.519e-02	-3.35	ARMS-mediated activation	REACTOME pathways	R-HSA-170984	249	3	10285	30	CAMK2G,NRG3,ERBB4
3.519e-02	-3.35	Signalling to p38 via RIT and RIN	REACTOME pathways	R-HSA-187706	249	3	10285	30	ERBB4,NRG3,CAMK2G
3.522e-02	-3.35	Ldl_recept_b	pfam domains	PF00058	13	1	17795	49	LRP1B
3.530e-02	-3.34	SMAD7 (SMAD family member 7)	protein interactions	4092	115	2	19454	50	PARD3,SOX5
3.530e-02	-3.34	DTNA (dystrobrevin alpha)	protein interactions	1837	115	2	19454	50	PARD3,NTRK2
3.533e-02	-3.34	EF_HAND_2	prosite domains	PS50222	215	3	12186	41	RYR3,DGKG,MACF1
3.540e-02	-3.34	SYT5 (synaptotagmin 5)	protein interactions	6861	14	1	19454	50	NRXN1
3.540e-02	-3.34	BOD1L2 (biorientation of chromosomes in cell division 1 like 2)	protein interactions	284257	14	1	19454	50	FMN2
3.540e-02	-3.34	TPSAB1 (tryptase alpha/beta 1)	protein interactions	7177	14	1	19454	50	CAMK2G
3.540e-02	-3.34	RSPO1 (R-spondin 1)	protein interactions	284654	14	1	19454	50	LRP1B
3.540e-02	-3.34	CFAP58 (cilia and flagella associated protein 58)	protein interactions	159686	14	1	19454	50	NAV2
3.540e-02	-3.34	CABS1 (calcium binding protein, spermatid associated 1)	protein interactions	85438	14	1	19454	50	GFAP
3.540e-02	-3.34	DACT2 (dishevelled binding antagonist of beta catenin 2)	protein interactions	168002	14	1	19454	50	CAMK2G
3.540e-02	-3.34	TAS2R7 (taste 2 receptor member 7)	protein interactions	50837	14	1	19454	50	PRKCA
3.540e-02	-3.34	ABTB1 (ankyrin repeat and BTB domain containing 1)	protein interactions	80325	14	1	19454	50	NTRK3
3.540e-02	-3.34	Nedd4 (neural precursor cell expressed, developmentally down-regulated 4)	protein interactions	17999	14	1	19454	50	GLIS3
3.540e-02	-3.34	SH3YL1 (SH3 and SYLF domain containing 1)	protein interactions	26751	14	1	19454	50	GFAP
3.540e-02	-3.34	SLC1A2 (solute carrier family 1 member 2)	protein interactions	6506	14	1	19454	50	SLC1A2
3.540e-02	-3.34	PLXNA4 (plexin A4)	protein interactions	91584	14	1	19454	50	GPM6A
3.540e-02	-3.34	Asap1 (ArfGAP with SH3 domain, ankyrin repeat and PH domain1)	protein interactions	13196	14	1	19454	50	MACF1
3.554e-02	-3.34	Frs2-mediated activation	REACTOME pathways	R-HSA-170968	250	3	10285	30	CAMK2G,NRG3,ERBB4
3.569e-02	-3.33	DYNLL1 (dynein light chain LC8-type 1)	protein interactions	8655	485	4	19454	50	NTRK3,PARD3,NTRK2,CAMK2G
3.574e-02	-3.33	human chr5p15.2	chromosome location	human chr5p15.2	19	1	26134	50	CTNND2
3.574e-02	-3.33	human chr11q25	chromosome location	human chr11q25	19	1	26134	50	NTM
3.574e-02	-3.33	human chr15q25.3	chromosome location	human chr15q25.3	19	1	26134	50	NTRK3
3.578e-02	-3.33	structural constituent of cytoskeleton	molecular function	GO:0005200	110	2	18094	49	GFAP,CTNNA2
3.589e-02	-3.33	plasma membrane raft	cellular component	GO:0044853	114	2	19108	50	SORBS1,ATP1A2
3.590e-02	-3.33	MAPK1/MAPK3 signaling	REACTOME pathways	R-HSA-5684996	251	3	10285	30	CAMK2G,NRG3,ERBB4
3.592e-02	-3.33	regulation of MAPK cascade	biological process	GO:0043408	669	5	18204	50	ERBB4,NDRG2,NTRK2,PRKCA,NTRK3
3.592e-02	-3.33	organic anion transmembrane transporter activity	molecular function	GO:0008514	268	3	18094	49	SLC4A4,SFXN5,SLC1A2
3.605e-02	-3.32	Intracellular Signalling Through LHCGR Receptor and Luteinizing Hormone/Choriogonadotropin	SMPDB pathways	SMP0000338	10	1	1369	5	ADCY2
3.612e-02	-3.32	postsynapse organization	biological process	GO:0099173	109	2	18204	50	CTNND2,NRXN1
3.617e-02	-3.32	small_intestine	COSMIC cancer mutations	small_intestine	250	3	16828	49	NTRK3,MACF1,MGAT4C
3.623e-02	-3.32	regulation of cellular process	biological process	GO:0050794	11468	38	18204	50	RYR3,MACF1,NDRG2,SORBS1,TNC,GPC5,KALRN,PSD2,SYNE1,MSI2,HPSE2,NTRK2,SLC1A2,ERBB4,CAMK2G,SLC4A4,DGKG,GFAP,GLIS3,RFX4,RPS6KA2,PRKCA,NRG3,ATP1A2,FMN2,DCLK2,RORA,NRXN1,CTNND2,CTNNA2,PITPNC1,NPAS3,ADCY2,DTNA,GPM6A,PARD3,NTRK3,SOX5
3.627e-02	-3.32	Prolonged ERK activation events	REACTOME pathways	R-HSA-169893	252	3	10285	30	CAMK2G,NRG3,ERBB4
3.627e-02	-3.32	Ion_trans	pfam domains	PF00520	109	2	17795	49	TRPM3,RYR3
3.645e-02	-3.31	MIR	smart domains	SM00472	10	1	9717	36	RYR3
3.645e-02	-3.31	DAGKa	smart domains	SM00045	10	1	9717	36	DGKG
3.647e-02	-3.31	Dppa3 (developmental pluripotency-associated 3)	protein interactions	73708	284	3	19454	50	CAMK2G,MSI2,ATP1A2
3.663e-02	-3.31	Signaling by Leptin	REACTOME pathways	R-HSA-2586552	253	3	10285	30	ERBB4,NRG3,CAMK2G
3.666e-02	-3.31	Stimuli-sensing channels	REACTOME pathways	R-HSA-2672351	104	2	10285	30	RYR3,TRPM3
3.668e-02	-3.31	CAV1 (caveolin 1)	protein interactions	857	719	5	19454	50	DTNA,RPS6KA2,MACF1,FMN2,PARD3
3.670e-02	-3.30	-	gene3d domains	3.10.450.50	12	1	14470	45	CAMK2G
3.670e-02	-3.30	Alpha-catenin/vinculin-like	gene3d domains	1.20.120.230	12	1	14470	45	CTNNA2
3.670e-02	-3.30	positive regulation of cell development	biological process	GO:0010720	458	4	18204	50	NTRK2,GFAP,PRKCA,MACF1
3.672e-02	-3.30	positive regulation of cell junction assembly	biological process	GO:1901890	110	2	18204	50	NRXN1,NTRK2
3.673e-02	-3.30	calcium ion binding	molecular function	GO:0005509	683	5	18094	49	LRP1B,MACF1,DGKG,NRXN1,RYR3
3.699e-02	-3.30	SIPA1L2 (signal induced proliferation associated 1 like 2)	protein interactions	57568	118	2	19454	50	GFAP,PARD3
3.699e-02	-3.30	DNM1 (dynamin 1)	protein interactions	1759	118	2	19454	50	GPM6A,PRKCA
3.715e-02	-3.29	regulation of multicellular organismal process	biological process	GO:0051239	3113	14	18204	50	RORA,NRXN1,ATP1A2,PRKCA,NDRG2,MACF1,GFAP,SOX5,ERBB4,CAMK2G,PARD3,SFXN5,NTRK2,SYNE1
3.715e-02	-3.29	Neurexin-like	interpro domains	IPR003585	14	1	18521	50	NRXN1
3.715e-02	-3.29	LDLR_classB_rpt	interpro domains	IPR000033	14	1	18521	50	LRP1B
3.719e-02	-3.29	stomach-carcinoma-adenocarcinoma	COSMIC cancer mutations	stomach-carcinoma-adenocarcinoma	15150	48	16828	49	CAMK2G,ATP1A2,PSD2,NDRG2,ADCY2,LRP1B,GPC5,SLC4A4,NRXN1,ERBB4,PITPNC1,MGAT4C,KALRN,DCLK2,SLC14A1,PARD3,MSI2,SYNE1,DTNA,RYR3,PRKCA,NTM,DGKG,FMN2,RPS6KA2,GLIS3,SFXN5,NRG3,SOX5,NTRK2,TNC,CTNND2,CDH20,LSAMP,NPAS3,HPSE2,ABLIM1,RORA,GPM6A,NAV2,MACF1,SORBS1,SLC1A2,NEBL,RFX4,NTRK3,GFAP,TRPM3
3.721e-02	-3.29	stomach-carcinoma-mucinous_adenocarcinoma	COSMIC cancer mutations	stomach-carcinoma-mucinous_adenocarcinoma	13	1	16828	49	NTRK3
3.721e-02	-3.29	mucinous_adenocarcinoma	COSMIC cancer mutations	mucinous_adenocarcinoma	13	1	16828	49	NTRK3
3.727e-02	-3.29	microtubule minus-end binding	molecular function	GO:0051011	14	1	18094	49	MACF1
3.727e-02	-3.29	L-glutamate transmembrane transporter activity	molecular function	GO:0005313	14	1	18094	49	SLC1A2
3.736e-02	-3.29	Interleukin receptor SHC signaling	REACTOME pathways	R-HSA-912526	255	3	10285	30	ERBB4,NRG3,CAMK2G
3.744e-02	-3.29	protein localization	biological process	GO:0008104	1954	10	18204	50	DCLK2,FMN2,PARD3,CAMK2G,ERBB4,NRXN1,GFAP,MACF1,SYNE1,LRP1B
3.745e-02	-3.28	HSPA1B (heat shock protein family A (Hsp70) member 1B)	protein interactions	3304	287	3	19454	50	NDRG2,NTRK3,NTRK2
3.756e-02	-3.28	ANKRD26 (ankyrin repeat domain containing 26)	protein interactions	22852	119	2	19454	50	NTRK2,PARD3
3.765e-02	-3.28	LRRCT	smart domains	SM00082	83	2	9717	36	NTRK2,NTRK3
3.771e-02	-3.28	protein localization to membrane	biological process	GO:0072657	462	4	18204	50	PARD3,MACF1,ERBB4,NRXN1
3.773e-02	-3.28	Signalling to RAS	REACTOME pathways	R-HSA-167044	256	3	10285	30	ERBB4,NRG3,CAMK2G
3.775e-02	-3.28	skin-malignant_melanoma	COSMIC cancer mutations	skin-malignant_melanoma	15741	49	16828	49	TNC,CTNND2,NTRK2,SOX5,LSAMP,NPAS3,CDH20,SORBS1,SLC1A2,ABLIM1,HPSE2,GPM6A,NAV2,MACF1,RORA,GFAP,TRPM3,NEBL,RFX4,NTRK3,ATP1A2,PSD2,CAMK2G,ERBB4,SLC4A4,NRXN1,ADCY2,LRP1B,GPC5,NDRG2,MSI2,SLC14A1,PARD3,SYNE1,MGAT4C,PITPNC1,DCLK2,KALRN,NKAIN3,NRG3,GLIS3,SFXN5,DTNA,DGKG,FMN2,RPS6KA2,RYR3,NTM,PRKCA
3.779e-02	-3.28	regulation of mesenchymal cell apoptotic process	biological process	GO:2001053	14	1	18204	50	SYNE1
3.779e-02	-3.28	negative regulation of sodium ion transmembrane transporter activity	biological process	GO:2000650	14	1	18204	50	ATP1A2
3.779e-02	-3.28	protein localization to postsynaptic specialization membrane	biological process	GO:0099633	14	1	18204	50	ERBB4
3.779e-02	-3.28	cellular response to purine-containing compound	biological process	GO:0071415	14	1	18204	50	RYR3
3.779e-02	-3.28	neurotransmitter receptor localization to postsynaptic specialization membrane	biological process	GO:0099645	14	1	18204	50	ERBB4
3.779e-02	-3.28	relaxation of cardiac muscle	biological process	GO:0055119	14	1	18204	50	ATP1A2
3.779e-02	-3.28	regulation of skeletal muscle adaptation	biological process	GO:0014733	14	1	18204	50	CAMK2G
3.779e-02	-3.28	response to forskolin	biological process	GO:1904321	14	1	18204	50	ADCY2
3.779e-02	-3.28	glutathione biosynthetic process	biological process	GO:0006750	14	1	18204	50	SLC1A2
3.779e-02	-3.28	mechanosensory behavior	biological process	GO:0007638	14	1	18204	50	NRXN1
3.779e-02	-3.28	cellular response to forskolin	biological process	GO:1904322	14	1	18204	50	ADCY2
3.788e-02	-3.27	PCSK1N (proprotein convertase subtilisin/kexin type 1 inhibitor)	protein interactions	27344	15	1	19454	50	MGAT4C
3.788e-02	-3.27	OGG1 (8-oxoguanine DNA glycosylase)	protein interactions	4968	15	1	19454	50	PRKCA
3.788e-02	-3.27	DEFB123 (defensin beta 123)	protein interactions	245936	15	1	19454	50	LRP1B
3.788e-02	-3.27	OLFM3 (olfactomedin 3)	protein interactions	118427	15	1	19454	50	LRP1B
3.788e-02	-3.27	TAFA5 (TAFA chemokine like family member 5)	protein interactions	25817	15	1	19454	50	NEBL
3.788e-02	-3.27	TIAM2 (TIAM Rac1 associated GEF 2)	protein interactions	26230	15	1	19454	50	PARD3
3.788e-02	-3.27	FN3K (fructosamine 3 kinase)	protein interactions	64122	15	1	19454	50	PRKCA
3.788e-02	-3.27	ENTPD5 (ectonucleoside triphosphate diphosphohydrolase 5 (inactive))	protein interactions	957	15	1	19454	50	PRKCA
3.788e-02	-3.27	ADRA1B (adrenoceptor alpha 1B)	protein interactions	147	15	1	19454	50	PRKCA
3.788e-02	-3.27	GRM7 (glutamate metabotropic receptor 7)	protein interactions	2917	15	1	19454	50	PRKCA
3.788e-02	-3.27	XIRP1 (xin actin binding repeat containing 1)	protein interactions	165904	15	1	19454	50	NEBL
3.794e-02	-3.27	regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction	biological process	GO:0051896	270	3	18204	50	NTRK3,NTRK2,ERBB4
3.797e-02	-3.27	active monoatomic ion transmembrane transporter activity	molecular function	GO:0022853	274	3	18094	49	SLC1A2,ATP1A2,SLC4A4
3.810e-02	-3.27	CEP128 (centrosomal protein 128)	protein interactions	145508	289	3	19454	50	NEBL,ABLIM1,SORBS1
3.814e-02	-3.27	IBTK (inhibitor of Bruton tyrosine kinase)	protein interactions	25998	120	2	19454	50	RPS6KA2,PRKCA
3.824e-02	-3.26	SH3	smart domains	SM00326	202	3	9717	36	SORBS1,KALRN,NEBL
3.836e-02	-3.26	cellular macromolecule localization	biological process	GO:0070727	1962	10	18204	50	MACF1,SYNE1,LRP1B,FMN2,PARD3,DCLK2,GFAP,NRXN1,ERBB4,CAMK2G
3.837e-02	-3.26	side of membrane	cellular component	GO:0098552	715	5	19108	50	NTM,DTNA,GPC5,LSAMP,GFAP
3.840e-02	-3.26	KIF14 (kinesin family member 14)	protein interactions	9928	1803	9	19454	50	MSI2,ABLIM1,NEBL,GFAP,PSD2,PARD3,SOX5,MACF1,SORBS1
3.855e-02	-3.26	axolemma	cellular component	GO:0030673	15	1	19108	50	SLC1A2
3.856e-02	-3.26	dendrite development	biological process	GO:0016358	113	2	18204	50	CTNND2,CTNNA2
3.861e-02	-3.25	Transport of inorganic cations/anions and amino acids/oligopeptides	REACTOME pathways	R-HSA-425393	107	2	10285	30	SLC4A4,SLC1A2
3.868e-02	-3.25	regulation of locomotion	biological process	GO:0040012	1164	7	18204	50	NRG3,NTRK3,ERBB4,TNC,MACF1,CTNNA2,PRKCA
3.876e-02	-3.25	GOPC (golgi associated PDZ and coiled-coil motif containing)	protein interactions	57120	291	3	19454	50	NTRK2,NTRK3,RPS6KA2
3.900e-02	-3.24	vascular process in circulatory system	biological process	GO:0003018	273	3	18204	50	ATP1A2,SLC4A4,SLC1A2
3.914e-02	-3.24	skin-leg-malignant_melanoma-nodular	COSMIC cancer mutations	skin-leg-malignant_melanoma-nodular	258	3	16828	49	FMN2,SYNE1,SLC4A4
3.936e-02	-3.23	Rap1 signaling pathway	KEGG pathways	hsa04015	210	3	7161	26	PRKCA,ADCY2,PARD3
3.936e-02	-3.23	Rap1 signaling pathway	KEGG pathways	ko04015	210	3	7161	26	PRKCA,PARD3,ADCY2
3.943e-02	-3.23	human chr13q31.3	chromosome location	human chr13q31.3	21	1	26134	50	GPC5
3.943e-02	-3.23	human chr10q23.1	chromosome location	human chr10q23.1	21	1	26134	50	NRG3
3.950e-02	-3.23	basal plasma membrane	cellular component	GO:0009925	288	3	19108	50	ERBB4,SLC4A4,SLC14A1
3.959e-02	-3.23	NAD+ Signalling and Aging	SMPDB pathways	SMP0084271	11	1	1369	5	RORA
3.971e-02	-3.23	gliogenesis	biological process	GO:0042063	275	3	18204	50	GFAP,NTRK2,PARD3
3.975e-02	-3.23	FH2_Formin	interpro domains	IPR015425	15	1	18521	50	FMN2
3.975e-02	-3.23	Sec7_C_sf	interpro domains	IPR023394	15	1	18521	50	PSD2
3.975e-02	-3.23	ATPase_P-typ_cation-transptr_C	interpro domains	IPR006068	15	1	18521	50	ATP1A2
3.975e-02	-3.23	Diacylglycerol_kinase_cat_dom	interpro domains	IPR001206	15	1	18521	50	DGKG
3.975e-02	-3.23	FH2_Formin_sf	interpro domains	IPR042201	15	1	18521	50	FMN2
3.975e-02	-3.23	NTF2-like_dom_sf	interpro domains	IPR032710	15	1	18521	50	CAMK2G
3.975e-02	-3.23	Sec7_dom_sf	interpro domains	IPR035999	15	1	18521	50	PSD2
3.988e-02	-3.22	low-density lipoprotein particle receptor activity	molecular function	GO:0005041	15	1	18094	49	LRP1B
3.988e-02	-3.22	tropomyosin binding	molecular function	GO:0005523	15	1	18094	49	NEBL
3.988e-02	-3.22	phosphatidylglycerol binding	molecular function	GO:1901611	15	1	18094	49	PITPNC1
3.988e-02	-3.22	3'-5' DNA helicase activity	molecular function	GO:0043138	15	1	18094	49	NAV2
3.988e-02	-3.22	filamin binding	molecular function	GO:0031005	15	1	18094	49	NEBL
3.988e-02	-3.22	BAD (BCL2 associated agonist of cell death)	protein interactions	572	123	2	19454	50	PRKCA,RPS6KA2
3.999e-02	-3.22	Interleukin-2 signaling	REACTOME pathways	R-HSA-451927	262	3	10285	30	NRG3,ERBB4,CAMK2G
4.002e-02	-3.22	solute:monoatomic cation symporter activity	molecular function	GO:0015294	117	2	18094	49	SLC4A4,SLC1A2
4.008e-02	-3.22	learning or memory	biological process	GO:0007611	276	3	18204	50	ATP1A2,NRXN1,NTRK2
4.009e-02	-3.22	GABAergic synapse	KEGG pathways	ko04727	88	2	7161	26	ADCY2,PRKCA
4.009e-02	-3.22	GABAergic synapse	KEGG pathways	hsa04727	88	2	7161	26	ADCY2,PRKCA
4.009e-02	-3.22	Gap junction	KEGG pathways	hsa04540	88	2	7161	26	PRKCA,ADCY2
4.009e-02	-3.22	Gap junction	KEGG pathways	ko04540	88	2	7161	26	ADCY2,PRKCA
4.010e-02	-3.22	DCC mediated attractive signaling	REACTOME pathways	R-HSA-418885	14	1	10285	30	ABLIM1
4.015e-02	-3.22	rhabdomyosarcoma	COSMIC cancer mutations	rhabdomyosarcoma	4150	18	16828	49	CDH20,LRP1B,ADCY2,FMN2,NTRK3,RYR3,TRPM3,NPAS3,GLIS3,MACF1,CAMK2G,NAV2,RORA,TNC,PARD3,SORBS1,SYNE1,CTNND2
4.035e-02	-3.21	IFFO2 (intermediate filament family orphan 2)	protein interactions	126917	16	1	19454	50	GFAP
4.035e-02	-3.21	RHO (rhodopsin)	protein interactions	6010	16	1	19454	50	PRKCA
4.035e-02	-3.21	TMEM134 (transmembrane protein 134)	protein interactions	80194	16	1	19454	50	ERBB4
4.035e-02	-3.21	SYT4 (synaptotagmin 4)	protein interactions	6860	16	1	19454	50	NRXN1
4.035e-02	-3.21	SLC6A9 (solute carrier family 6 member 9)	protein interactions	6536	16	1	19454	50	PRKCA
4.035e-02	-3.21	GABRR1 (gamma-aminobutyric acid type A receptor subunit rho1)	protein interactions	2569	16	1	19454	50	PRKCA
4.035e-02	-3.21	KLHL25 (kelch like family member 25)	protein interactions	64410	16	1	19454	50	RPS6KA2
4.035e-02	-3.21	WASH6P (WASP family homolog 6, pseudogene)	protein interactions	653440	16	1	19454	50	NTRK3
4.035e-02	-3.21	CAMK1G (calcium/calmodulin dependent protein kinase IG)	protein interactions	57172	16	1	19454	50	CAMK2G
4.035e-02	-3.21	AMMECR1L (AMMECR1 like)	protein interactions	83607	16	1	19454	50	MACF1
4.035e-02	-3.21	SAPCD1 (suppressor APC domain containing 1)	protein interactions	401251	16	1	19454	50	CTNNA2
4.035e-02	-3.21	DUS1L (dihydrouridine synthase 1 like)	protein interactions	64118	16	1	19454	50	CAMK2G
4.035e-02	-3.21	CNTNAP2 (contactin associated protein 2)	protein interactions	26047	16	1	19454	50	MACF1
4.035e-02	-3.21	SYT9 (synaptotagmin 9)	protein interactions	143425	16	1	19454	50	NRXN1
4.035e-02	-3.21	WWC3 (WWC family member 3)	protein interactions	55841	16	1	19454	50	PRKCA
4.035e-02	-3.21	SYTL2 (synaptotagmin like 2)	protein interactions	54843	16	1	19454	50	NRXN1
4.035e-02	-3.21	GABRB3 (gamma-aminobutyric acid type A receptor subunit beta3)	protein interactions	2562	16	1	19454	50	PRKCA
4.035e-02	-3.21	ADAM18 (ADAM metallopeptidase domain 18)	protein interactions	8749	16	1	19454	50	RPS6KA2
4.035e-02	-3.21	NRGN (neurogranin)	protein interactions	4900	16	1	19454	50	PRKCA
4.035e-02	-3.21	CDH12 (cadherin 12)	protein interactions	1010	16	1	19454	50	CTNNA2
4.038e-02	-3.21	Signalling to ERKs	REACTOME pathways	R-HSA-187687	263	3	10285	30	NRG3,ERBB4,CAMK2G
4.043e-02	-3.21	cerebellar Purkinje cell layer formation	biological process	GO:0021694	15	1	18204	50	RORA
4.043e-02	-3.21	sarcoplasmic reticulum calcium ion transport	biological process	GO:0070296	15	1	18204	50	RYR3
4.043e-02	-3.21	positive regulation of glycogen biosynthetic process	biological process	GO:0045725	15	1	18204	50	SORBS1
4.043e-02	-3.21	response to caffeine	biological process	GO:0031000	15	1	18204	50	RYR3
4.043e-02	-3.21	negative regulation of sodium ion transmembrane transport	biological process	GO:1902306	15	1	18204	50	ATP1A2
4.043e-02	-3.21	peripheral nervous system neuron differentiation	biological process	GO:0048934	15	1	18204	50	NTRK2
4.043e-02	-3.21	neuroblast division	biological process	GO:0055057	15	1	18204	50	SOX5
4.043e-02	-3.21	peripheral nervous system neuron development	biological process	GO:0048935	15	1	18204	50	NTRK2
4.043e-02	-3.21	pyramidal neuron differentiation	biological process	GO:0021859	15	1	18204	50	DCLK2
4.043e-02	-3.21	regulation of neuron projection arborization	biological process	GO:0150011	15	1	18204	50	MACF1
4.043e-02	-3.21	protein homotrimerization	biological process	GO:0070207	15	1	18204	50	SLC1A2
4.043e-02	-3.21	intracellular potassium ion homeostasis	biological process	GO:0030007	15	1	18204	50	ATP1A2
4.047e-02	-3.21	TNK2 (tyrosine kinase non receptor 2)	protein interactions	10188	124	2	19454	50	NTRK3,NTRK2
4.047e-02	-3.21	CEBPA (CCAAT enhancer binding protein alpha)	protein interactions	1050	124	2	19454	50	MACF1,GFAP
4.053e-02	-3.21	DAGK_cat	pfam domains	PF00781	15	1	17795	49	DGKG
4.053e-02	-3.21	Sec7	pfam domains	PF01369	15	1	17795	49	PSD2
4.053e-02	-3.21	FH2	pfam domains	PF02181	15	1	17795	49	FMN2
4.053e-02	-3.21	CRAL_TRIO_2	pfam domains	PF13716	15	1	17795	49	KALRN
4.053e-02	-3.21	Cation_ATPase_C	pfam domains	PF00689	15	1	17795	49	ATP1A2
4.055e-02	-3.21	positive regulation of MAPK cascade	biological process	GO:0043410	473	4	18204	50	NTRK3,PRKCA,NTRK2,ERBB4
4.069e-02	-3.20	LZTS2 (leucine zipper tumor suppressor 2)	protein interactions	84445	506	4	19454	50	SORBS1,GFAP,NEBL,PARD3
4.079e-02	-3.20	TJP1 (tight junction protein 1)	protein interactions	7082	297	3	19454	50	NEBL,DTNA,PARD3
4.080e-02	-3.20	actin filament organization	biological process	GO:0007015	278	3	18204	50	NEBL,FMN2,SORBS1
4.101e-02	-3.19	Ig-like_dom_sf	interpro domains	IPR036179	483	4	18521	50	LSAMP,NTRK3,NTM,NTRK2
4.106e-02	-3.19	TCHP (trichoplein keratin filament binding)	protein interactions	84260	125	2	19454	50	GFAP,PARD3
4.106e-02	-3.19	STXBP1 (syntaxin binding protein 1)	protein interactions	6812	125	2	19454	50	PRKCA,GPM6A
4.107e-02	-3.19	regulation of synapse assembly	biological process	GO:0051963	117	2	18204	50	NTRK2,NRXN1
4.115e-02	-3.19	FCERI mediated MAPK activation	REACTOME pathways	R-HSA-2871796	265	3	10285	30	ERBB4,NRG3,CAMK2G
4.126e-02	-3.19	Integration of energy metabolism	REACTOME pathways	R-HSA-163685	111	2	10285	30	ADCY2,PRKCA
4.127e-02	-3.19	human chr3q13.31	chromosome location	human chr3q13.31	22	1	26134	50	LSAMP
4.166e-02	-3.18	SYP (synaptophysin)	protein interactions	6855	126	2	19454	50	PITPNC1,GPM6A
4.215e-02	-3.17	MFAP5-mediated ovarian cancer cell motility and invasiveness	WikiPathways	WP3301	12	1	5310	19	RYR3
4.226e-02	-3.16	DES (desmin)	protein interactions	1674	127	2	19454	50	DTNA,GFAP
4.226e-02	-3.16	SCO2 (synthesis of cytochrome C oxidase 2)	protein interactions	9997	127	2	19454	50	DCLK2,NTRK3
4.235e-02	-3.16	Sec7_dom	interpro domains	IPR000904	16	1	18521	50	PSD2
4.239e-02	-3.16	perinuclear region of cytoplasm	cellular component	GO:0048471	735	5	19108	50	NDRG2,SYNE1,FMN2,NTRK2,PRKCA
4.248e-02	-3.16	lamin binding	molecular function	GO:0005521	16	1	18094	49	SYNE1
4.248e-02	-3.16	adenylate cyclase activity	molecular function	GO:0004016	16	1	18094	49	ADCY2
4.248e-02	-3.16	oxysterol binding	molecular function	GO:0008142	16	1	18094	49	RORA
4.248e-02	-3.16	diacylglycerol-dependent serine/threonine kinase activity	molecular function	GO:0004697	16	1	18094	49	PRKCA
4.261e-02	-3.16	Morphine addiction	KEGG pathways	hsa05032	91	2	7161	26	ADCY2,PRKCA
4.261e-02	-3.16	Morphine addiction	KEGG pathways	ko05032	91	2	7161	26	PRKCA,ADCY2
4.265e-02	-3.15	Wnt signaling pathway	biological process	GO:0016055	283	3	18204	50	NDRG2,CTNND2,MACF1
4.269e-02	-3.15	-	gene3d domains	2.60.200.40	14	1	14470	45	DGKG
4.269e-02	-3.15	-	gene3d domains	2.20.25.10	14	1	14470	45	TNC
4.282e-02	-3.15	SHD (Src homology 2 domain containing transforming protein D)	protein interactions	56961	17	1	19454	50	ERBB4
4.282e-02	-3.15	PAX4 (paired box 4)	protein interactions	5078	17	1	19454	50	NTM
4.282e-02	-3.15	MSANTD2 (Myb/SANT DNA binding domain containing 2)	protein interactions	79684	17	1	19454	50	SOX5
4.282e-02	-3.15	CLEC4M (C-type lectin domain family 4 member M)	protein interactions	10332	17	1	19454	50	GFAP
4.282e-02	-3.15	NEU3 (neuraminidase 3)	protein interactions	10825	17	1	19454	50	NTRK3
4.282e-02	-3.15	Shcbp1 (Shc SH2-domain binding protein 1)	protein interactions	20419	17	1	19454	50	GPC5
4.282e-02	-3.15	TNNT2 (troponin T2, cardiac type)	protein interactions	7139	17	1	19454	50	PRKCA
4.282e-02	-3.15	PDE7A (phosphodiesterase 7A)	protein interactions	5150	17	1	19454	50	PRKCA
4.282e-02	-3.15	DPP6 (dipeptidyl peptidase like 6)	protein interactions	1804	17	1	19454	50	GPM6A
4.282e-02	-3.15	CYP3A4 (cytochrome P450 family 3 subfamily A member 4)	protein interactions	1576	17	1	19454	50	PRKCA
4.282e-02	-3.15	LIPT1 (lipoyltransferase 1)	protein interactions	51601	17	1	19454	50	PRKCA
4.282e-02	-3.15	SEPSECS (Sep (O-phosphoserine) tRNA:Sec (selenocysteine) tRNA synthase)	protein interactions	51091	17	1	19454	50	ABLIM1
4.282e-02	-3.15	TAGAP (T cell activation RhoGTPase activating protein)	protein interactions	117289	17	1	19454	50	DTNA
4.282e-02	-3.15	KRTAP19-3 (keratin associated protein 19-3)	protein interactions	337970	17	1	19454	50	CAMK2G
4.282e-02	-3.15	FAM163B (family with sequence similarity 163 member B)	protein interactions	642968	17	1	19454	50	CAMK2G
4.286e-02	-3.15	ATF7IP (activating transcription factor 7 interacting protein)	protein interactions	55729	128	2	19454	50	SOX5,MACF1
4.286e-02	-3.15	PRKAR2B (protein kinase cAMP-dependent type II regulatory subunit beta)	protein interactions	5577	128	2	19454	50	PRKCA,GPM6A
4.286e-02	-3.15	SH3BP4 (SH3 domain binding protein 4)	protein interactions	23677	128	2	19454	50	NTRK3,PARD3
4.286e-02	-3.15	FARP1 (FERM, ARH/RhoGEF and pleckstrin domain protein 1)	protein interactions	10160	128	2	19454	50	PARD3,PSD2
4.289e-02	-3.15	LDLRB	prosite domains	PS51120	13	1	12186	41	LRP1B
4.290e-02	-3.15	Adenylate cyclase inhibitory pathway	REACTOME pathways	R-HSA-170670	15	1	10285	30	ADCY2
4.290e-02	-3.15	WNT5A-dependent internalization of FZD4	REACTOME pathways	R-HSA-5099900	15	1	10285	30	PRKCA
4.290e-02	-3.15	Depolymerisation of the Nuclear Lamina	REACTOME pathways	R-HSA-4419969	15	1	10285	30	PRKCA
4.290e-02	-3.15	Inhibition of adenylate cyclase pathway	REACTOME pathways	R-HSA-997269	15	1	10285	30	ADCY2
4.290e-02	-3.15	N-Glycan antennae elongation	REACTOME pathways	R-HSA-975577	15	1	10285	30	MGAT4C
4.297e-02	-3.15	RAC1 (Rac family small GTPase 1)	protein interactions	5879	1005	6	19454	50	FMN2,PARD3,KALRN,DTNA,PRKCA,MACF1
4.299e-02	-3.15	regulation of peptidyl-serine phosphorylation	biological process	GO:0033135	120	2	18204	50	NTRK2,NTRK3
4.307e-02	-3.14	nonribosomal peptide biosynthetic process	biological process	GO:0019184	16	1	18204	50	SLC1A2
4.307e-02	-3.14	regulation of postsynaptic neurotransmitter receptor internalization	biological process	GO:0099149	16	1	18204	50	SYNE1
4.307e-02	-3.14	regulation of amino acid transmembrane transport	biological process	GO:1903789	16	1	18204	50	ATP1A2
4.307e-02	-3.14	positive regulation of macrophage differentiation	biological process	GO:0045651	16	1	18204	50	PRKCA
4.307e-02	-3.14	regulation of respiratory system process	biological process	GO:0044065	16	1	18204	50	ATP1A2
4.307e-02	-3.14	neuron cell-cell adhesion	biological process	GO:0007158	16	1	18204	50	NRXN1
4.307e-02	-3.14	regulation of amino acid import across plasma membrane	biological process	GO:0010958	16	1	18204	50	ATP1A2
4.307e-02	-3.14	locomotory exploration behavior	biological process	GO:0035641	16	1	18204	50	ATP1A2
4.311e-02	-3.14	human chr2q34	chromosome location	human chr2q34	23	1	26134	50	ERBB4
4.311e-02	-3.14	human chr5p15.31	chromosome location	human chr5p15.31	23	1	26134	50	ADCY2
4.313e-02	-3.14	Lactose Degradation	SMPDB pathways	SMP0000457	12	1	1369	5	ATP1A2
4.313e-02	-3.14	Lactose Intolerance	SMPDB pathways	SMP0000458	12	1	1369	5	ATP1A2
4.321e-02	-3.14	CARM1 (coactivator associated arginine methyltransferase 1)	protein interactions	10498	304	3	19454	50	CAMK2G,DTNA,RORA
4.346e-02	-3.14	Progesterone-mediated oocyte maturation	KEGG pathways	hsa04914	92	2	7161	26	RPS6KA2,ADCY2
4.346e-02	-3.14	Progesterone-mediated oocyte maturation	KEGG pathways	ko04914	92	2	7161	26	RPS6KA2,ADCY2
4.346e-02	-3.14	SLC38A2 (solute carrier family 38 member 2)	protein interactions	54407	129	2	19454	50	RPS6KA2,PARD3
4.351e-02	-3.13	Interleukin-3, 5 and GM-CSF signaling	REACTOME pathways	R-HSA-512988	271	3	10285	30	NRG3,ERBB4,CAMK2G
4.358e-02	-3.13	protein complex involved in cell-matrix adhesion	cellular component	GO:0098637	17	1	19108	50	TNC
4.407e-02	-3.12	DVL1 (dishevelled segment polarity protein 1)	protein interactions	1855	130	2	19454	50	RPS6KA2,PARD3
4.426e-02	-3.12	neuron projection terminus	cellular component	GO:0044306	128	2	19108	50	SLC1A2,NTRK2
4.444e-02	-3.11	ASX_HYDROXYL	prosite domains	PS00010	100	2	12186	41	NRXN1,LRP1B
4.446e-02	-3.11	G Protein Signaling Pathways	WikiPathways	WP35	95	2	5310	19	ADCY2,PRKCA
4.481e-02	-3.11	thyroid	COSMIC cancer mutations	thyroid	9867	35	16828	49	SOX5,CTNND2,PSD2,TNC,ATP1A2,ADCY2,CDH20,LRP1B,GPC5,NDRG2,ERBB4,SLC4A4,NRXN1,LSAMP,NAV2,DCLK2,MACF1,RORA,KALRN,ABLIM1,SLC1A2,SYNE1,SLC14A1,PARD3,DGKG,FMN2,RPS6KA2,NTRK3,RYR3,PRKCA,DTNA,NRG3,GLIS3,GFAP,TRPM3
4.482e-02	-3.11	system process	biological process	GO:0003008	2015	10	18204	50	RYR3,CTNNA2,NAV2,SLC1A2,NTRK2,ABLIM1,ATP1A2,DTNA,SLC4A4,NRXN1
4.492e-02	-3.10	muscle cell differentiation	biological process	GO:0042692	289	3	18204	50	RORA,NEBL,SYNE1
4.493e-02	-3.10	ATP-NAD_kinase_N	interpro domains	IPR017438	17	1	18521	50	DGKG
4.493e-02	-3.10	NAD/diacylglycerol_kinase_sf	interpro domains	IPR016064	17	1	18521	50	DGKG
4.493e-02	-3.10	A/G_cyclase_CS	interpro domains	IPR018297	17	1	18521	50	ADCY2
4.499e-02	-3.10	ITCH (itchy E3 ubiquitin protein ligase)	protein interactions	83737	309	3	19454	50	ERBB4,GLIS3,RORA
4.507e-02	-3.10	ductal_carcinoma	COSMIC cancer mutations	ductal_carcinoma	15798	49	16828	49	LSAMP,NPAS3,CDH20,TNC,CTNND2,SOX5,NTRK2,GFAP,TRPM3,NEBL,RFX4,NTRK3,SORBS1,SLC1A2,HPSE2,ABLIM1,RORA,GPM6A,NAV2,MACF1,SLC4A4,NRXN1,ERBB4,NDRG2,ADCY2,LRP1B,GPC5,ATP1A2,PSD2,CAMK2G,NKAIN3,GLIS3,SFXN5,NRG3,DTNA,RYR3,NTM,PRKCA,DGKG,FMN2,RPS6KA2,PARD3,SLC14A1,MSI2,SYNE1,PITPNC1,MGAT4C,KALRN,DCLK2
4.529e-02	-3.09	OPCML (opioid binding protein/cell adhesion molecule like)	protein interactions	4978	18	1	19454	50	NTM
4.529e-02	-3.09	SELL (selectin L)	protein interactions	6402	18	1	19454	50	PRKCA
4.529e-02	-3.09	ORF45 (ORF45)	protein interactions	4961474	18	1	19454	50	RPS6KA2
4.529e-02	-3.09	NECTIN1 (nectin cell adhesion molecule 1)	protein interactions	5818	18	1	19454	50	PARD3
4.529e-02	-3.09	Cnot2 (CCR4-NOT transcription complex, subunit 2)	protein interactions	72068	18	1	19454	50	MACF1
4.529e-02	-3.09	ADAT2 (adenosine deaminase tRNA specific 2)	protein interactions	134637	18	1	19454	50	NAV2
4.529e-02	-3.09	TTC29 (tetratricopeptide repeat domain 29)	protein interactions	83894	18	1	19454	50	MACF1
4.529e-02	-3.09	ZNF224 (zinc finger protein 224)	protein interactions	7767	18	1	19454	50	LRP1B
4.529e-02	-3.09	ACAP1 (ArfGAP with coiled-coil, ankyrin repeat and PH domains 1)	protein interactions	9744	18	1	19454	50	NEBL
4.529e-02	-3.09	IRGC (immunity related GTPase cinema)	protein interactions	56269	18	1	19454	50	RPS6KA2
4.530e-02	-3.09	ADD3 (adducin 3)	protein interactions	120	132	2	19454	50	PRKCA,RPS6KA2
4.551e-02	-3.09	Z disc	cellular component	GO:0030018	130	2	19108	50	RYR3,NEBL
4.553e-02	-3.09	NCAM signaling for neurite out-growth	REACTOME pathways	R-HSA-375165	276	3	10285	30	CAMK2G,ERBB4,NRG3
4.558e-02	-3.09	Cell-type Dependent Selectivity of CCK2R Signaling	WikiPathways	WP3679	13	1	5310	19	RYR3
4.560e-02	-3.09	action potential	biological process	GO:0001508	124	2	18204	50	ATP1A2,NTRK2
4.560e-02	-3.09	cardiocyte differentiation	biological process	GO:0035051	124	2	18204	50	NEBL,SYNE1
4.567e-02	-3.09	Arf Nucleotide-binding Site Opener,domain 2	gene3d domains	1.10.1000.11	15	1	14470	45	PSD2
4.567e-02	-3.09	Formin, FH2 domain	gene3d domains	1.20.58.2220	15	1	14470	45	FMN2
4.567e-02	-3.09	inorganic ion transmembrane transport	biological process	GO:0098660	715	5	18204	50	ATP1A2,RYR3,GPM6A,TRPM3,SLC4A4
4.570e-02	-3.09	PKA activation	REACTOME pathways	R-HSA-163615	16	1	10285	30	ADCY2
4.570e-02	-3.09	Regulation of KIT signaling	REACTOME pathways	R-HSA-1433559	16	1	10285	30	PRKCA
4.570e-02	-3.09	branch elongation of an epithelium	biological process	GO:0060602	17	1	18204	50	TNC
4.570e-02	-3.09	cGMP metabolic process	biological process	GO:0046068	17	1	18204	50	RORA
4.570e-02	-3.09	membrane depolarization during cardiac muscle cell action potential	biological process	GO:0086012	17	1	18204	50	ATP1A2
4.570e-02	-3.09	preganglionic parasympathetic fiber development	biological process	GO:0021783	17	1	18204	50	NAV2
4.570e-02	-3.09	T-helper 17 type immune response	biological process	GO:0072538	17	1	18204	50	RORA
4.570e-02	-3.09	protein trimerization	biological process	GO:0070206	17	1	18204	50	SLC1A2
4.570e-02	-3.09	positive regulation of glycogen metabolic process	biological process	GO:0070875	17	1	18204	50	SORBS1
4.570e-02	-3.09	cellular response to ATP	biological process	GO:0071318	17	1	18204	50	RYR3
4.570e-02	-3.09	cell migration in hindbrain	biological process	GO:0021535	17	1	18204	50	CTNNA2
4.570e-02	-3.09	retinal rod cell differentiation	biological process	GO:0060221	17	1	18204	50	NTRK2
4.570e-02	-3.09	mammary gland epithelial cell differentiation	biological process	GO:0060644	17	1	18204	50	ERBB4
4.570e-02	-3.09	cell communication by electrical coupling involved in cardiac conduction	biological process	GO:0086064	17	1	18204	50	ATP1A2
4.579e-02	-3.08	signaling receptor binding	molecular function	GO:0005102	1493	8	18094	49	SORBS1,TNC,SYNE1,PRKCA,ERBB4,GFAP,NRXN1,NRG3
4.581e-02	-3.08	ZZ	pfam domains	PF00569	17	1	17795	49	DTNA
4.626e-02	-3.07	actomyosin structure organization	biological process	GO:0031032	125	2	18204	50	SORBS1,NEBL
4.626e-02	-3.07	mammary gland development	biological process	GO:0030879	125	2	18204	50	NRG3,ERBB4
4.627e-02	-3.07	basal part of cell	cellular component	GO:0045178	307	3	19108	50	SLC4A4,ERBB4,SLC14A1
4.631e-02	-3.07	cellular response to growth factor stimulus	biological process	GO:0071363	494	4	18204	50	SOX5,NTRK2,ERBB4,NTRK3
4.653e-02	-3.07	NUFIP1 (nuclear FMR1 interacting protein 1)	protein interactions	26747	134	2	19454	50	GPM6A,NTM
4.654e-02	-3.07	channel activity	molecular function	GO:0015267	502	4	18094	49	RYR3,GPM6A,TRPM3,SLC14A1
4.665e-02	-3.07	Succinate Signalling During Inflammation	SMPDB pathways	SMP0084634	13	1	1369	5	PRKCA
4.665e-02	-3.07	Trehalose Degradation	SMPDB pathways	SMP0000467	13	1	1369	5	ATP1A2
4.682e-02	-3.06	passive transmembrane transporter activity	molecular function	GO:0022803	503	4	18094	49	GPM6A,TRPM3,SLC14A1,RYR3
4.693e-02	-3.06	limbic system development	biological process	GO:0021761	126	2	18204	50	DCLK2,ATP1A2
4.715e-02	-3.05	DVL2 (dishevelled segment polarity protein 2)	protein interactions	1856	531	4	19454	50	SYNE1,MACF1,PRKCA,PARD3
4.716e-02	-3.05	Myo1c (myosin IC)	protein interactions	17913	135	2	19454	50	CAMK2G,ABLIM1
4.720e-02	-3.05	Signal Transduction	REACTOME pathways	R-HSA-162582	2547	12	10285	30	PARD3,CAMK2G,ERBB4,GPC5,DGKG,PRKCA,ADCY2,NRG3,RPS6KA2,KALRN,NTRK2,GFAP
4.722e-02	-3.05	central_nervous_system-brain-glioma-astrocytoma_Grade_IV	COSMIC cancer mutations	central_nervous_system-brain-glioma-astrocytoma_Grade_IV	15813	49	16828	49	CDH20,NPAS3,LSAMP,NTRK2,SOX5,CTNND2,TNC,NTRK3,NEBL,RFX4,GFAP,TRPM3,NAV2,GPM6A,MACF1,RORA,ABLIM1,HPSE2,SORBS1,SLC1A2,ADCY2,LRP1B,GPC5,NDRG2,ERBB4,SLC4A4,NRXN1,CAMK2G,PSD2,ATP1A2,DGKG,FMN2,RPS6KA2,RYR3,NTM,PRKCA,DTNA,NRG3,GLIS3,SFXN5,NKAIN3,DCLK2,KALRN,MGAT4C,PITPNC1,SYNE1,MSI2,PARD3,SLC14A1
4.743e-02	-3.05	striated_muscle	COSMIC cancer mutations	striated_muscle	4228	18	16828	49	TNC,PARD3,SORBS1,SYNE1,CTNND2,CAMK2G,MACF1,NAV2,RORA,TRPM3,GLIS3,NPAS3,CDH20,LRP1B,ADCY2,FMN2,NTRK3,RYR3
4.746e-02	-3.05	Growth_fac_rcpt_cys_sf	interpro domains	IPR009030	129	2	18521	50	ERBB4,LRP1B
4.752e-02	-3.05	ATPase_P-typ_cation-transptr_N	interpro domains	IPR004014	18	1	18521	50	ATP1A2
4.752e-02	-3.05	A/G_cyclase	interpro domains	IPR001054	18	1	18521	50	ADCY2
4.752e-02	-3.05	Furin_repeat	interpro domains	IPR006212	18	1	18521	50	ERBB4
4.752e-02	-3.05	Nucleotide_cyclase	interpro domains	IPR029787	18	1	18521	50	ADCY2
4.760e-02	-3.05	response to amino acid	biological process	GO:0043200	127	2	18204	50	NTRK2,SLC1A2
4.766e-02	-3.04	phosphatidylcholine transporter activity	molecular function	GO:0008525	18	1	18094	49	PITPNC1
4.766e-02	-3.04	lipoprotein particle receptor activity	molecular function	GO:0030228	18	1	18094	49	LRP1B
4.766e-02	-3.04	GABA receptor binding	molecular function	GO:0050811	18	1	18094	49	ERBB4
4.766e-02	-3.04	intracellularly gated calcium channel activity	molecular function	GO:0015278	18	1	18094	49	RYR3
4.766e-02	-3.04	acidic amino acid transmembrane transporter activity	molecular function	GO:0015172	18	1	18094	49	SLC1A2
4.766e-02	-3.04	heparan sulfate proteoglycan binding	molecular function	GO:0043395	18	1	18094	49	HPSE2
4.766e-02	-3.04	transmembrane receptor protein tyrosine kinase activator activity	molecular function	GO:0030297	18	1	18094	49	NRG3
4.772e-02	-3.04	haematopoietic_and_lymphoid_tissue-abdomen-lymphoid_neoplasm-diffuse_large_B_cell_lymphoma	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue-abdomen-lymphoid_neoplasm-diffuse_large_B_cell_lymphoma	120	2	16828	49	FMN2,CTNND2
4.774e-02	-3.04	HBEGF (heparin binding EGF like growth factor)	protein interactions	1839	19	1	19454	50	ERBB4
4.774e-02	-3.04	SYT7 (synaptotagmin 7)	protein interactions	9066	19	1	19454	50	NRXN1
4.774e-02	-3.04	EGFL6 (EGF like domain multiple 6)	protein interactions	25975	19	1	19454	50	LRP1B
4.774e-02	-3.04	TRPV6 (transient receptor potential cation channel subfamily V member 6)	protein interactions	55503	19	1	19454	50	PRKCA
4.774e-02	-3.04	Mtx1 (metaxin 1)	protein interactions	17827	19	1	19454	50	CAMK2G
4.774e-02	-3.04	CNTNAP4 (contactin associated protein family member 4)	protein interactions	85445	19	1	19454	50	MACF1
4.774e-02	-3.04	SPZ1 (spermatogenic leucine zipper 1)	protein interactions	84654	19	1	19454	50	DTNA
4.774e-02	-3.04	LTC4S (leukotriene C4 synthase)	protein interactions	4056	19	1	19454	50	CAMK2G
4.774e-02	-3.04	NLGN1 (neuroligin 1)	protein interactions	22871	19	1	19454	50	NRXN1
4.774e-02	-3.04	KCNF1 (potassium voltage-gated channel modifier subfamily F member 1)	protein interactions	3754	19	1	19454	50	GFAP
4.774e-02	-3.04	PHYHIPL (phytanoyl-CoA 2-hydroxylase interacting protein like)	protein interactions	84457	19	1	19454	50	GPM6A
4.774e-02	-3.04	ANKRD13C (ankyrin repeat domain 13C)	protein interactions	81573	19	1	19454	50	NTRK3
4.774e-02	-3.04	GCHFR (GTP cyclohydrolase I feedback regulator)	protein interactions	2644	19	1	19454	50	NEBL
4.774e-02	-3.04	C3orf62 (chromosome 3 open reading frame 62)	protein interactions	375341	19	1	19454	50	ATP1A2
4.774e-02	-3.04	PDP2 (pyruvate dehydrogenase phosphatase catalytic subunit 2)	protein interactions	57546	19	1	19454	50	GFAP
4.774e-02	-3.04	OSM (oncostatin M)	protein interactions	5008	19	1	19454	50	TRPM3
4.774e-02	-3.04	ZNF532 (zinc finger protein 532)	protein interactions	55205	19	1	19454	50	ERBB4
4.774e-02	-3.04	JSRP1 (junctional sarcoplasmic reticulum protein 1)	protein interactions	126306	19	1	19454	50	PRKCA
4.774e-02	-3.04	RIT2 (Ras like without CAAX 2)	protein interactions	6014	19	1	19454	50	DTNA
4.779e-02	-3.04	NUDT19 (nudix hydrolase 19)	protein interactions	390916	136	2	19454	50	GFAP,NTRK3
4.779e-02	-3.04	AHCYL2 (adenosylhomocysteinase like 2)	protein interactions	23382	136	2	19454	50	NTRK3,RPS6KA2
4.781e-02	-3.04	Phosphatidylinositol signaling system	KEGG pathways	hsa04070	97	2	7161	26	DGKG,PRKCA
4.781e-02	-3.04	Phosphatidylinositol signaling system	KEGG pathways	ko04070	97	2	7161	26	PRKCA,DGKG
4.782e-02	-3.04	regulation of multicellular organismal development	biological process	GO:2000026	1484	8	18204	50	PARD3,SOX5,GFAP,NRXN1,ERBB4,MACF1,PRKCA,NTRK2
4.804e-02	-3.04	muscle system process	biological process	GO:0003012	297	3	18204	50	RYR3,ATP1A2,DTNA
4.822e-02	-3.03	cell population proliferation	biological process	GO:0008283	726	5	18204	50	GFAP,SOX5,RORA,NDRG2,HPSE2
4.827e-02	-3.03	myelination	biological process	GO:0042552	128	2	18204	50	NTRK2,PARD3
4.832e-02	-3.03	regulation of protein kinase C signaling	biological process	GO:0090036	18	1	18204	50	DGKG
4.832e-02	-3.03	cardiac myofibril assembly	biological process	GO:0055003	18	1	18204	50	NEBL
4.832e-02	-3.03	positive regulation of circadian rhythm	biological process	GO:0042753	18	1	18204	50	RORA
4.832e-02	-3.03	negative regulation of anoikis	biological process	GO:2000811	18	1	18204	50	NTRK2
4.832e-02	-3.03	negative regulation of sodium ion transport	biological process	GO:0010766	18	1	18204	50	ATP1A2
4.832e-02	-3.03	positive regulation of myelination	biological process	GO:0031643	18	1	18204	50	PARD3
4.832e-02	-3.03	dendritic spine morphogenesis	biological process	GO:0060997	18	1	18204	50	CTNND2
4.842e-02	-3.03	TBL1X (transducin beta like 1 X-linked)	protein interactions	6907	137	2	19454	50	SOX5,DGKG
4.843e-02	-3.03	Ras signaling in the CD4+ TCR pathway	Pathway Interaction DB	tcrraspathway	11	1	2226	10	PRKCA
4.843e-02	-3.03	oligoastrocytoma_Grade_II	COSMIC cancer mutations	oligoastrocytoma_Grade_II	121	2	16828	49	CDH20,DTNA
4.844e-02	-3.03	Guanylate_cyc	pfam domains	PF00211	18	1	17795	49	ADCY2
4.844e-02	-3.03	Cation_ATPase_N	pfam domains	PF00690	18	1	17795	49	ATP1A2
4.848e-02	-3.03	CREB phosphorylation through the activation of CaMKII	REACTOME pathways	R-HSA-442729	17	1	10285	30	CAMK2G
4.848e-02	-3.03	PKA activation in glucagon signalling	REACTOME pathways	R-HSA-164378	17	1	10285	30	ADCY2
4.848e-02	-3.03	PKA-mediated phosphorylation of CREB	REACTOME pathways	R-HSA-111931	17	1	10285	30	ADCY2
4.848e-02	-3.03	TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)	REACTOME pathways	R-HSA-2173791	17	1	10285	30	PARD3
4.848e-02	-3.03	Unblocking of NMDA receptor, glutamate binding and activation	REACTOME pathways	R-HSA-438066	17	1	10285	30	CAMK2G
4.848e-02	-3.03	Trafficking of GluR2-containing AMPA receptors	REACTOME pathways	R-HSA-416993	17	1	10285	30	PRKCA
4.859e-02	-3.02	cation-transporting ATPase complex	cellular component	GO:0090533	19	1	19108	50	ATP1A2
4.859e-02	-3.02	parallel fiber to Purkinje cell synapse	cellular component	GO:0098688	19	1	19108	50	GPM6A
4.859e-02	-3.02	human chr18q12.1	chromosome location	human chr18q12.1	26	1	26134	50	DTNA
4.900e-02	-3.02	ERK Pathway in Huntington's Disease	WikiPathways	WP3853	14	1	5310	19	NTRK2
4.905e-02	-3.01	PRKAG1 (protein kinase AMP-activated non-catalytic subunit gamma 1)	protein interactions	5571	138	2	19454	50	NTRK3,SFXN5
4.905e-02	-3.01	STAM2 (signal transducing adaptor molecule 2)	protein interactions	10254	138	2	19454	50	NTRK3,NTRK2
4.932e-02	-3.01	FH2	prosite domains	PS51444	15	1	12186	41	FMN2
4.932e-02	-3.01	DAGK	prosite domains	PS50146	15	1	12186	41	DGKG
4.932e-02	-3.01	SEC7	prosite domains	PS50190	15	1	12186	41	PSD2
4.959e-02	-3.00	Choline metabolism in cancer	KEGG pathways	ko05231	99	2	7161	26	DGKG,PRKCA
4.959e-02	-3.00	Choline metabolism in cancer	KEGG pathways	hsa05231	99	2	7161	26	PRKCA,DGKG
4.962e-02	-3.00	ensheathment of neurons	biological process	GO:0007272	130	2	18204	50	NTRK2,PARD3
4.962e-02	-3.00	axon ensheathment	biological process	GO:0008366	130	2	18204	50	PARD3,NTRK2
4.968e-02	-3.00	SPCS2 (signal peptidase complex subunit 2)	protein interactions	9789	139	2	19454	50	MGAT4C,GPC5
4.968e-02	-3.00	MAGI1 (membrane associated guanylate kinase, WW and PDZ domain containing 1)	protein interactions	9223	139	2	19454	50	PARD3,RPS6KA2
4.987e-02	-3.00	bone-humerus-chondrosarcoma	COSMIC cancer mutations	bone-humerus-chondrosarcoma	123	2	16828	49	KALRN,LRP1B