Gene Ontology Enrichment Results

Homer de novo Motif Enrichment Results
Known Motif Enrichment Results

Text file version of complete results (i.e. open with Excel)

biological process: Functional groupings of proteins (Gene Ontology)

molecular function: Mechanistic actions of proteins (Gene Ontology)

cellular component: Protein localization (Gene Ontology)

chromosome location: Genes with similar chromosome localization (NCBI Gene)

KEGG pathways: Groups of proteins in the same pathways (KEGG)

protein interactions: "Proteins interacting with a common protein (BIND, EcoCyc, HPRD)" (NCBI Gene)

interpro domains: Proteins with similar domains and features (Interpro)

pfam domains: Proteins with similar domains and features (Pfam)

smart domains: Proteins with similar domains and features (SMART)

gene3d domains: Proteins with similar domains and features (Gene3D)

prosite domains: Proteins with similar domains and features (Prosite)

prints domains: Proteins with similar domains and features (PRINTS)

MSigDB lists: "Genes sets for pathways, factor/miRNA target predictions, expression patterns, etc." (MSigDB)

BIOCYC pathways: Groups of proteins in the same pathways (BIOCYC)

COSMIC cancer mutations: Genes mutated in similar cancers (COSMIC)

GWAS genes: Genes mutated in similar diseases (GWAS Catalog)

Lipid Maps pathways: Groups of proteins in the same lipid pathways (Lipid Maps/Biosystems)

Pathway Interaction DB: Groups of proteins in the same pathways (Pathway Interaction Database)

REACTOME pathways: Groups of proteins in the same pathways (REACTOME)

SMPDB pathways: Groups of proteins in the same pathways (SMPDB)

WikiPathways: Groups of proteins in the same pathways (Wikipathways)

Enriched Categories

P-value	ln(P)	Term	GO Tree	GO ID	# of Genes in Term	# of Target Genes in Term	# of Total Genes	# of Target Genes	Common Genes
2.230e-08	-17.62	acute_lymphoblastic_B_cell_leukaemia	COSMIC cancer mutations	acute_lymphoblastic_B_cell_leukaemia	3828	29	16828	48	HIF3A,NTRK2,NRCAM,PARD3,GPC5,SLC1A2,NAV3,NKAIN3,PAMR1,GLIS3,RORA,NRG3,LSAMP,SLC4A4,BMPR1B,NEBL,PTPRZ1,SPON1,CPE,SOX5,ATP13A4,ADCY2,GPM6A,CTNND2,CSGALNACT1,MGAT4C,FMN2,HPSE2,TNIK
2.230e-08	-17.62	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-acute_lymphoblastic_B_cell_leukaemia	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-acute_lymphoblastic_B_cell_leukaemia	3828	29	16828	48	HPSE2,CSGALNACT1,MGAT4C,FMN2,TNIK,SPON1,GPM6A,ATP13A4,SOX5,CPE,ADCY2,CTNND2,NRG3,LSAMP,PAMR1,RORA,GLIS3,SLC4A4,PTPRZ1,BMPR1B,NEBL,HIF3A,GPC5,NKAIN3,NAV3,SLC1A2,NTRK2,PARD3,NRCAM
3.024e-08	-17.31	diffuse_large_B_cell_lymphoma	COSMIC cancer mutations	diffuse_large_B_cell_lymphoma	4151	30	16828	48	NTRK2,EFEMP1,PARD3,TRPS1,GPC5,NAV3,NKAIN3,SLC1A2,DTNA,MAP3K5,AQP4,NEBL,RORA,NRG3,LSAMP,DPP10,CLU,CTNND2,SPON1,GPM6A,ATP13A4,ADCY2,CPE,SOX5,ATP1A2,MACF1,TNIK,CSGALNACT1,FMN2,HPSE2
7.610e-08	-16.39	myelodysplastic_syndrome	COSMIC cancer mutations	myelodysplastic_syndrome	1174	16	16828	48	NPAS3,BMPR1B,TNIK,DCLK2,HPSE2,NRG3,LSAMP,NTRK2,PARD3,SLC1A2,NKAIN3,RPS6KA2,SOX5,ADCY2,MAP3K5,ATP1A2
7.610e-08	-16.39	haematopoietic_and_lymphoid_tissue-haematopoietic_neoplasm-myelodysplastic_syndrome	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue-haematopoietic_neoplasm-myelodysplastic_syndrome	1174	16	16828	48	RPS6KA2,NKAIN3,SLC1A2,NTRK2,PARD3,ATP1A2,MAP3K5,SOX5,ADCY2,TNIK,NPAS3,BMPR1B,NRG3,HPSE2,DCLK2,LSAMP
8.128e-08	-16.33	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-chronic_lymphocytic_leukaemia-small_lymphocytic_lymphoma	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-chronic_lymphocytic_leukaemia-small_lymphocytic_lymphoma	3511	27	16828	48	MAP3K5,DTNA,MSI2,GPC5,NRCAM,TRPM3,PARD3,EFEMP1,NTRK2,LSAMP,NRG3,PAMR1,BMPR1B,PTPRZ1,SLC4A4,MACF1,ADCY2,CPE,SPON1,CTNND2,CLU,HPSE2,FMN2,MGAT4C,TNIK,PITPNC1,NPAS3
8.128e-08	-16.33	chronic_lymphocytic_leukaemia-small_lymphocytic_lymphoma	COSMIC cancer mutations	chronic_lymphocytic_leukaemia-small_lymphocytic_lymphoma	3511	27	16828	48	SLC4A4,PTPRZ1,BMPR1B,PAMR1,NRG3,LSAMP,NTRK2,EFEMP1,PARD3,TRPM3,NRCAM,GPC5,MSI2,DTNA,MAP3K5,NPAS3,PITPNC1,TNIK,MGAT4C,FMN2,HPSE2,CLU,CTNND2,SPON1,CPE,ADCY2,MACF1
8.476e-08	-16.28	prostate-carcinoma	COSMIC cancer mutations	prostate-carcinoma	9000	43	16828	48	CLU,CTNND2,DPP10,MACF1,GPM6A,CPE,SOX5,ATP13A4,ADCY2,SPON1,TNIK,PITPNC1,NPAS3,HPSE2,FMN2,RFX4,CSGALNACT1,RPS6KA2,NAV3,NKAIN3,SLC1A2,GPC5,TRPS1,ABLIM1,PARD3,TRPM3,NRCAM,NTRK2,EFEMP1,HIF3A,MAP3K5,MSI2,DTNA,PTPRZ1,NEBL,BMPR1B,SLC4A4,LSAMP,SORBS1,NRG3,DCLK2,RORA,GLIS3
8.519e-08	-16.28	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-Burkitt_lymphoma	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-Burkitt_lymphoma	2119	21	16828	48	RFX4,FMN2,CSGALNACT1,LSAMP,HPSE2,NRG3,BMPR1B,NPAS3,ATP13A4,MAP3K5,CPE,SOX5,ADCY2,GPM6A,SPON1,PARD3,NTRK2,SLC1A2,CTNND2,NKAIN3,GPC5
8.519e-08	-16.28	Burkitt_lymphoma	COSMIC cancer mutations	Burkitt_lymphoma	2119	21	16828	48	HPSE2,NRG3,LSAMP,CSGALNACT1,RFX4,FMN2,NPAS3,BMPR1B,SPON1,ADCY2,SOX5,ATP13A4,MAP3K5,CPE,GPM6A,GPC5,CTNND2,SLC1A2,NKAIN3,NTRK2,PARD3
1.359e-07	-15.81	mantle_cell_lymphoma	COSMIC cancer mutations	mantle_cell_lymphoma	2849	24	16828	48	NEBL,RFX4,FMN2,NRG3,HPSE2,LSAMP,NTRK2,EFEMP1,PARD3,TRPM3,GPC5,TRPS1,NAV3,NKAIN3,CTNND2,SLC1A2,SPON1,GPM6A,CPE,ADCY2,SOX5,ATP13A4,MAP3K5,HIF3A
1.498e-07	-15.71	cerebellum	COSMIC cancer mutations	cerebellum	769	13	16828	48	CTNND2,ABLIM1,GPC5,NRCAM,PARD3,DPP10,NTRK2,CPE,NEBL,PTPRZ1,NPAS3,NRG3,HPSE2
1.498e-07	-15.71	system development	biological process	GO:0048731	3533	26	18204	49	PTPRZ1,RFX4,TRPS1,LSAMP,TNIK,CTNND2,DCLK2,SOX5,ATP1A2,NRG3,CLU,NEBL,MSI2,HIF3A,CSGALNACT1,CTNNA2,EFEMP1,CPE,NAV3,PARD3,BMPR1B,RORA,SLC1A2,GPM6A,NTRK2,NRCAM
2.036e-07	-15.41	central_nervous_system-cerebellum-primitive_neuroectodermal_tumour-medulloblastoma-SHH_subtype	COSMIC cancer mutations	central_nervous_system-cerebellum-primitive_neuroectodermal_tumour-medulloblastoma-SHH_subtype	653	12	16828	48	NRCAM,PARD3,DPP10,NTRK2,CTNND2,ABLIM1,CPE,NEBL,PTPRZ1,NPAS3,HPSE2,NRG3
2.070e-07	-15.39	SHH_subtype	COSMIC cancer mutations	SHH_subtype	654	12	16828	48	HPSE2,NRG3,NPAS3,PTPRZ1,NEBL,CPE,NTRK2,DPP10,PARD3,NRCAM,ABLIM1,CTNND2
2.083e-07	-15.38	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-plasma_cell_myeloma	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-plasma_cell_myeloma	1263	16	16828	48	NEBL,TNIK,FMN2,PAMR1,NRG3,HPSE2,NTRK2,CTNND2,RPS6KA2,NAV3,TRPS1,ABLIM1,ATP13A4,ADCY2,GPM6A,MACF1
2.083e-07	-15.38	plasma_cell_myeloma	COSMIC cancer mutations	plasma_cell_myeloma	1263	16	16828	48	MACF1,ATP13A4,ADCY2,GPM6A,CTNND2,RPS6KA2,NAV3,TRPS1,ABLIM1,NTRK2,HPSE2,NRG3,FMN2,PAMR1,TNIK,NEBL
2.363e-07	-15.26	skin-face-carcinoma-squamous_cell_carcinoma	COSMIC cancer mutations	skin-face-carcinoma-squamous_cell_carcinoma	2036	20	16828	48	GPM6A,MSI2,AQP4,MACF1,PARD3,TRPM3,DPP10,RPS6KA2,NAV3,TRPS1,GPC5,ABLIM1,FMN2,RORA,CSGALNACT1,LSAMP,RBMS3,NRG3,PTPRZ1,NEBL
3.120e-07	-14.98	nervous system development	biological process	GO:0007399	2185	20	18204	49	NRCAM,CTNNA2,NTRK2,MSI2,GPM6A,SLC1A2,CLU,RORA,BMPR1B,NRG3,ATP1A2,PARD3,SOX5,NAV3,DCLK2,LSAMP,TNIK,CTNND2,RFX4,PTPRZ1
4.239e-07	-14.67	lymph_node	COSMIC cancer mutations	lymph_node	1703	18	16828	48	NTRK2,DPP10,PARD3,TRPM3,TRPS1,GPC5,NAV3,RPS6KA2,CTNND2,DTNA,GPM6A,ATP13A4,SOX5,MAP3K5,NEBL,TNIK,NRG3,LSAMP
5.280e-07	-14.45	PRNP (prion protein (Kanno blood group))	protein interactions	5621	1118	14	19454	50	AQP4,MSI2,PTPRZ1,CPE,ABLIM1,GPM6A,LSAMP,TRPM3,ATP1A2,SLC4A4,SORBS1,TRPS1,MACF1,CLU
5.302e-07	-14.45	face	COSMIC cancer mutations	face	2139	20	16828	48	PTPRZ1,NEBL,CSGALNACT1,FMN2,RORA,NRG3,LSAMP,RBMS3,DPP10,PARD3,TRPM3,ABLIM1,TRPS1,GPC5,RPS6KA2,NAV3,MSI2,GPM6A,MACF1,AQP4
5.510e-07	-14.41	cell periphery	cellular component	GO:0071944	6020	33	19108	50	PTPRZ1,CTNND2,CLU,DTNA,TRPM3,SLC1A2,EFEMP1,GPM6A,HPSE2,ADCY2,MACF1,TNIK,SLC4A4,GPC5,ATP1A2,AQP4,PARD3,MAP3K5,SORBS1,DPP10,LSAMP,BMPR1B,NKAIN3,NRCAM,CTNNA2,FMN2,CPE,SPON1,NRG3,NTRK2,MAPK10,HIF3A,ATP13A4
6.796e-07	-14.20	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-diffuse_large_B_cell_lymphoma	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-diffuse_large_B_cell_lymphoma	3608	26	16828	48	HPSE2,FMN2,CSGALNACT1,TNIK,MACF1,ATP1A2,GPM6A,SOX5,ADCY2,ATP13A4,CPE,SPON1,CLU,CTNND2,LSAMP,NRG3,RORA,NEBL,AQP4,MAP3K5,NAV3,NKAIN3,SLC1A2,GPC5,PARD3,EFEMP1
7.347e-07	-14.12	follicular_lymphoma	COSMIC cancer mutations	follicular_lymphoma	1209	15	16828	48	GPC5,CTNND2,NKAIN3,DPP10,EFEMP1,PARD3,AQP4,SPON1,SOX5,ADCY2,TNIK,NRG3,HPSE2,LSAMP,RORA
1.085e-06	-13.73	haematopoietic_and_lymphoid_tissue-haematopoietic_neoplasm	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue-haematopoietic_neoplasm	764	12	16828	48	NRG3,HPSE2,LSAMP,ATP1A2,ADCY2,SOX5,MAP3K5,GPC5,NKAIN3,SLC1A2,NTRK2,PARD3
1.375e-06	-13.50	oesophagus-carcinoma-squamous_cell_carcinoma	COSMIC cancer mutations	oesophagus-carcinoma-squamous_cell_carcinoma	6486	35	16828	48	AQP4,HIF3A,MAP3K5,NAV3,RPS6KA2,TRPS1,ABLIM1,GPC5,TRPM3,PARD3,SORBS1,DCLK2,NRG3,GLIS3,BMPR1B,NEBL,PTPRZ1,SLC4A4,MACF1,ATP1A2,CPE,ATP13A4,ADCY2,SOX5,GPM6A,SPON1,CTNND2,DPP10,HPSE2,FMN2,MGAT4C,CSGALNACT1,TNIK,PITPNC1,NPAS3
1.387e-06	-13.49	central_nervous_system-brain-primitive_neuroectodermal_tumour-medulloblastoma	COSMIC cancer mutations	central_nervous_system-brain-primitive_neuroectodermal_tumour-medulloblastoma	7205	37	16828	48	MAP3K5,ABLIM1,GPC5,TRPS1,NAV3,NKAIN3,RPS6KA2,SLC1A2,NTRK2,PARD3,TRPM3,NRG3,DCLK2,SORBS1,LSAMP,PAMR1,RORA,GLIS3,SLC4A4,PTPRZ1,NEBL,MACF1,SPON1,GPM6A,SOX5,ATP13A4,ADCY2,CPE,CTNND2,DPP10,HPSE2,CSGALNACT1,FMN2,RFX4,TNIK,NPAS3,PITPNC1
1.470e-06	-13.43	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-mantle_cell_lymphoma	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-mantle_cell_lymphoma	2737	22	16828	48	LSAMP,NRG3,NEBL,HIF3A,MAP3K5,NKAIN3,NAV3,SLC1A2,TRPS1,GPC5,PARD3,NTRK2,EFEMP1,HPSE2,RFX4,FMN2,GPM6A,SOX5,ADCY2,CPE,SPON1,CTNND2
1.499e-06	-13.41	central nervous system development	biological process	GO:0007417	995	13	18204	49	CLU,RORA,BMPR1B,CTNNA2,NRCAM,SLC1A2,MSI2,NTRK2,RFX4,PTPRZ1,NRG3,ATP1A2,DCLK2
1.525e-06	-13.39	multicellular organism development	biological process	GO:0007275	3957	26	18204	49	SOX5,DCLK2,ATP1A2,NRG3,PTPRZ1,LSAMP,TNIK,CTNND2,TRPS1,RFX4,HIF3A,MSI2,CTNNA2,CSGALNACT1,NEBL,CLU,NAV3,PARD3,EFEMP1,CPE,NTRK2,GPM6A,SLC1A2,NRCAM,BMPR1B,RORA
1.623e-06	-13.33	CTNNA1 (catenin alpha 1)	protein interactions	1495	325	8	19454	50	CTNNA2,PARD3,TNIK,NEBL,DTNA,ABLIM1,SORBS1,MACF1
2.063e-06	-13.09	anatomical structure morphogenesis	biological process	GO:0009653	2225	19	18204	49	SOX5,PARD3,NRG3,EFEMP1,PTPRZ1,CTNND2,TNIK,CPE,ABLIM1,NTRK2,HIF3A,GPM6A,NRCAM,CTNNA2,CSGALNACT1,BMPR1B,NEBL,RORA,CLU
2.170e-06	-13.04	neuronal action potential propagation	biological process	GO:0019227	10	3	18204	49	NRCAM,ATP1A2,NTRK2
2.170e-06	-13.04	action potential propagation	biological process	GO:0098870	10	3	18204	49	NTRK2,NRCAM,ATP1A2
2.712e-06	-12.82	carcinoid-endocrine_tumour	COSMIC cancer mutations	carcinoid-endocrine_tumour	7752	38	16828	48	SLC4A4,PTPRZ1,NEBL,BMPR1B,NRG3,DCLK2,LSAMP,PAMR1,GLIS3,RORA,GPC5,ABLIM1,TRPS1,RPS6KA2,NKAIN3,SLC1A2,NTRK2,EFEMP1,PARD3,TRPM3,NRCAM,MAP3K5,TNIK,HPSE2,CSGALNACT1,FMN2,RFX4,CLU,CTNND2,DPP10,ATP1A2,MACF1,SPON1,GPM6A,CPE,ADCY2,ATP13A4,SOX5
3.650e-06	-12.52	MAPT (microtubule associated protein tau)	protein interactions	4137	948	12	19454	50	SORBS1,GPM6A,ABLIM1,SLC1A2,MAPK10,LSAMP,CLU,NEBL,TNIK,ATP1A2,CTNNA2,CTNND2
4.119e-06	-12.40	OCLN (occludin)	protein interactions	100506658	495	9	19454	50	NTRK2,EFEMP1,MACF1,ABLIM1,FMN2,DTNA,RPS6KA2,PARD3,TNIK
4.189e-06	-12.38	lymphoid_neoplasm	COSMIC cancer mutations	lymphoid_neoplasm	12233	47	16828	48	NPAS3,TNIK,CSGALNACT1,HPSE2,SPON1,ATP13A4,ADCY2,GPM6A,ATP1A2,SLC4A4,BMPR1B,PAMR1,RORA,DCLK2,NRG3,EFEMP1,NTRK2,TRPM3,PARD3,TRPS1,GPC5,NAV3,DTNA,MSI2,HIF3A,PITPNC1,MGAT4C,FMN2,RFX4,DPP10,CTNND2,CLU,SOX5,CPE,MACF1,NEBL,PTPRZ1,GLIS3,SORBS1,LSAMP,NRCAM,ABLIM1,SLC1A2,NKAIN3,RPS6KA2,MAP3K5,AQP4
4.791e-06	-12.25	plasma membrane	cellular component	GO:0005886	5538	30	19108	50	CTNNA2,FMN2,NKAIN3,NRCAM,ATP13A4,MAPK10,HIF3A,CPE,NRG3,NTRK2,SLC4A4,GPC5,LSAMP,BMPR1B,SORBS1,DPP10,MAP3K5,ATP1A2,AQP4,PARD3,GPM6A,SLC1A2,TNIK,MACF1,ADCY2,HPSE2,PTPRZ1,TRPM3,DTNA,CTNND2
4.968e-06	-12.21	pharynx	COSMIC cancer mutations	pharynx	2696	21	16828	48	DTNA,ATP13A4,ATP1A2,MACF1,DPP10,EFEMP1,NTRK2,NRCAM,GPC5,SLC1A2,CTNND2,RPS6KA2,CLU,FMN2,RFX4,NRG3,SORBS1,SLC4A4,NPAS3,PITPNC1,PTPRZ1
7.103e-06	-11.85	neurogenesis	biological process	GO:0022008	1334	14	18204	49	CLU,RORA,BMPR1B,NRCAM,CTNNA2,GPM6A,NTRK2,TNIK,CTNND2,PTPRZ1,PARD3,DCLK2,SOX5,NAV3
8.691e-06	-11.65	trunk	COSMIC cancer mutations	trunk	3554	24	16828	48	HPSE2,MGAT4C,NPAS3,ATP1A2,MACF1,CPE,ATP13A4,SOX5,CTNND2,DPP10,NRG3,DCLK2,LSAMP,GLIS3,PTPRZ1,NEBL,HIF3A,MAP3K5,ABLIM1,TRPS1,RPS6KA2,NTRK2,PARD3,NRCAM
8.945e-06	-11.62	upper_aerodigestive_tract-mouth-carcinoma-squamous_cell_carcinoma	COSMIC cancer mutations	upper_aerodigestive_tract-mouth-carcinoma-squamous_cell_carcinoma	6953	35	16828	48	NRCAM,TRPM3,PARD3,ABLIM1,TRPS1,GPC5,SLC1A2,NAV3,RPS6KA2,DTNA,MAP3K5,HIF3A,SLC4A4,NEBL,PTPRZ1,PAMR1,RORA,DCLK2,NRG3,SORBS1,LSAMP,CTNND2,SPON1,ATP13A4,SOX5,ADCY2,GPM6A,ATP1A2,MACF1,PITPNC1,TNIK,CSGALNACT1,MGAT4C,RFX4,FMN2
1.209e-05	-11.32	nodular	COSMIC cancer mutations	nodular	1515	15	16828	48	NEBL,PTPRZ1,SLC4A4,NPAS3,GLIS3,FMN2,DCLK2,NTRK2,CTNND2,ABLIM1,CPE,ATP13A4,MACF1,HIF3A,ATP1A2
1.231e-05	-11.31	regulation of chondrocyte differentiation	biological process	GO:0032330	53	4	18204	49	SOX5,BMPR1B,EFEMP1,TRPS1
1.278e-05	-11.27	right_lower_lobe	COSMIC cancer mutations	right_lower_lobe	5692	31	16828	48	PAMR1,NRG3,SORBS1,LSAMP,SLC4A4,PTPRZ1,NEBL,DTNA,MAP3K5,NTRK2,PARD3,TRPM3,NRCAM,GPC5,TRPS1,NAV3,NKAIN3,MGAT4C,FMN2,HPSE2,NPAS3,SPON1,GPM6A,ADCY2,SOX5,ATP13A4,ATP1A2,MACF1,DPP10,CLU,CTNND2
1.278e-05	-11.27	lung-right_lower_lobe-carcinoma-adenocarcinoma	COSMIC cancer mutations	lung-right_lower_lobe-carcinoma-adenocarcinoma	5692	31	16828	48	NPAS3,FMN2,MGAT4C,HPSE2,DPP10,CLU,CTNND2,GPM6A,SOX5,ADCY2,ATP13A4,SPON1,MACF1,ATP1A2,PTPRZ1,NEBL,SLC4A4,PAMR1,LSAMP,SORBS1,NRG3,PARD3,NRCAM,TRPM3,NTRK2,NAV3,NKAIN3,TRPS1,GPC5,MAP3K5,DTNA
1.404e-05	-11.17	mouth	COSMIC cancer mutations	mouth	9004	40	16828	48	DTNA,MAP3K5,HIF3A,EFEMP1,NTRK2,TRPM3,NRCAM,PARD3,GPC5,ABLIM1,TRPS1,SLC1A2,NAV3,RPS6KA2,PAMR1,RORA,DCLK2,NRG3,LSAMP,SORBS1,SLC4A4,NEBL,PTPRZ1,SPON1,ATP13A4,SOX5,ADCY2,GPM6A,ATP1A2,MACF1,CTNND2,CLU,MGAT4C,CSGALNACT1,RFX4,FMN2,HPSE2,NPAS3,PITPNC1,TNIK
1.423e-05	-11.16	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-follicular_lymphoma	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-follicular_lymphoma	981	12	16828	48	EFEMP1,PARD3,GPC5,NKAIN3,CTNND2,SPON1,RORA,SOX5,ADCY2,NRG3,HPSE2,LSAMP
1.696e-05	-10.98	chondroblastoma	COSMIC cancer mutations	chondroblastoma	534	9	16828	48	GPC5,NKAIN3,CTNND2,NRG3,LSAMP,FMN2,GPM6A,ADCY2,SOX5
2.698e-05	-10.52	anatomical structure development	biological process	GO:0048856	5207	28	18204	49	BMPR1B,RORA,SLC1A2,GPM6A,NTRK2,NRCAM,EFEMP1,ABLIM1,CPE,NAV3,PARD3,CLU,NEBL,MSI2,HIF3A,CSGALNACT1,CTNNA2,PTPRZ1,TRPS1,RFX4,TNIK,LSAMP,CTNND2,DCLK2,SOX5,NRG3,ATP1A2,FMN2
3.986e-05	-10.13	scalp	COSMIC cancer mutations	scalp	2110	17	16828	48	PTPRZ1,NEBL,SLC4A4,SORBS1,LSAMP,RBMS3,RORA,FMN2,RPS6KA2,NAV3,GPC5,TRPS1,NRCAM,MACF1,ATP1A2,SOX5,ATP13A4
4.197e-05	-10.08	neuron projection morphogenesis	biological process	GO:0048812	486	8	18204	49	PTPRZ1,GPM6A,BMPR1B,PARD3,TNIK,NRCAM,CTNNA2,CTNND2
4.245e-05	-10.07	generation of neurons	biological process	GO:0048699	1158	12	18204	49	BMPR1B,RORA,NTRK2,GPM6A,CTNNA2,NRCAM,PTPRZ1,TNIK,CTNND2,SOX5,DCLK2,PARD3
4.399e-05	-10.03	regulation of cartilage development	biological process	GO:0061035	73	4	18204	49	TRPS1,SOX5,EFEMP1,BMPR1B
4.512e-05	-10.01	plasma membrane bounded cell projection morphogenesis	biological process	GO:0120039	491	8	18204	49	PARD3,CTNNA2,TNIK,NRCAM,CTNND2,PTPRZ1,GPM6A,BMPR1B
4.567e-05	-9.99	skin-trunk-malignant_melanoma-nodular	COSMIC cancer mutations	skin-trunk-malignant_melanoma-nodular	1291	13	16828	48	NTRK2,ABLIM1,CTNND2,CPE,ATP13A4,ATP1A2,MACF1,HIF3A,NPAS3,NEBL,PTPRZ1,GLIS3,DCLK2
4.847e-05	-9.93	cell projection morphogenesis	biological process	GO:0048858	496	8	18204	49	TNIK,CTNND2,BMPR1B,PTPRZ1,NRCAM,CTNNA2,PARD3,GPM6A
5.891e-05	-9.74	acute_myeloid_leukaemia_therapy_related	COSMIC cancer mutations	acute_myeloid_leukaemia_therapy_related	1523	14	16828	48	RORA,FMN2,LSAMP,HPSE2,NRG3,NEBL,ADCY2,SOX5,SPON1,PARD3,NTRK2,CTNND2,NKAIN3,GPC5
5.891e-05	-9.74	haematopoietic_and_lymphoid_tissue-haematopoietic_neoplasm-acute_myeloid_leukaemia_therapy_related	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue-haematopoietic_neoplasm-acute_myeloid_leukaemia_therapy_related	1523	14	16828	48	SPON1,ADCY2,SOX5,GPC5,CTNND2,NKAIN3,NTRK2,PARD3,HPSE2,NRG3,LSAMP,FMN2,RORA,NEBL
6.375e-05	-9.66	negative regulation of amyloid-beta formation	biological process	GO:1902430	29	3	18204	49	NTRK2,CLU,SPON1
6.877e-05	-9.58	lung-carcinoma-small_cell_carcinoma	COSMIC cancer mutations	lung-carcinoma-small_cell_carcinoma	9908	41	16828	48	TNIK,PITPNC1,NPAS3,HPSE2,FMN2,RFX4,CSGALNACT1,MGAT4C,CLU,CTNND2,DPP10,MACF1,ATP1A2,GPM6A,ATP13A4,SOX5,CPE,SPON1,PTPRZ1,NEBL,BMPR1B,SLC4A4,SORBS1,NRG3,DCLK2,RORA,PAMR1,RPS6KA2,NAV3,NKAIN3,GPC5,TRPS1,ABLIM1,PARD3,NRCAM,TRPM3,NTRK2,HIF3A,MAP3K5,MSI2,DTNA
6.988e-05	-9.57	small_cell_carcinoma	COSMIC cancer mutations	small_cell_carcinoma	9913	41	16828	48	HIF3A,MSI2,DTNA,MAP3K5,TRPS1,GPC5,ABLIM1,RPS6KA2,NKAIN3,NAV3,NTRK2,PARD3,NRCAM,TRPM3,NRG3,DCLK2,SORBS1,PAMR1,RORA,SLC4A4,PTPRZ1,BMPR1B,NEBL,ATP1A2,MACF1,SPON1,GPM6A,SOX5,ATP13A4,CPE,CLU,CTNND2,DPP10,HPSE2,MGAT4C,CSGALNACT1,FMN2,RFX4,TNIK,NPAS3,PITPNC1
7.360e-05	-9.52	lung-right_upper_lobe-carcinoma-adenocarcinoma	COSMIC cancer mutations	lung-right_upper_lobe-carcinoma-adenocarcinoma	10376	42	16828	48	GLIS3,RORA,PAMR1,SORBS1,LSAMP,DCLK2,NRG3,NEBL,BMPR1B,PTPRZ1,SLC4A4,MAP3K5,DTNA,HIF3A,NRCAM,TRPM3,PARD3,EFEMP1,NTRK2,SLC1A2,NAV3,NKAIN3,TRPS1,GPC5,ABLIM1,RFX4,FMN2,MGAT4C,CSGALNACT1,HPSE2,PITPNC1,NPAS3,TNIK,CPE,ATP13A4,SOX5,ADCY2,GPM6A,SPON1,MACF1,ATP1A2,CTNND2
7.360e-05	-9.52	right_upper_lobe	COSMIC cancer mutations	right_upper_lobe	10376	42	16828	48	FMN2,RFX4,CSGALNACT1,MGAT4C,HPSE2,PITPNC1,NPAS3,TNIK,CPE,SOX5,ADCY2,ATP13A4,GPM6A,SPON1,MACF1,ATP1A2,CTNND2,RORA,GLIS3,PAMR1,LSAMP,SORBS1,DCLK2,NRG3,BMPR1B,NEBL,PTPRZ1,SLC4A4,MAP3K5,DTNA,HIF3A,TRPM3,NRCAM,PARD3,EFEMP1,NTRK2,SLC1A2,NAV3,NKAIN3,TRPS1,GPC5,ABLIM1
7.813e-05	-9.46	negative regulation of amyloid precursor protein catabolic process	biological process	GO:1902992	31	3	18204	49	SPON1,CLU,NTRK2
7.817e-05	-9.46	cell morphogenesis	biological process	GO:0000902	687	9	18204	49	GPM6A,CTNNA2,NRCAM,PARD3,BMPR1B,PTPRZ1,TNIK,CTNND2,CLU
7.981e-05	-9.44	neuron development	biological process	GO:0048666	859	10	18204	49	BMPR1B,PTPRZ1,CTNND2,TNIK,NTRK2,DCLK2,GPM6A,CTNNA2,NRCAM,PARD3
8.349e-05	-9.39	multicellular organismal process	biological process	GO:0032501	6177	30	18204	49	BMPR1B,RORA,GPM6A,SLC1A2,NTRK2,NRCAM,EFEMP1,CPE,ABLIM1,NAV3,PARD3,CLU,DTNA,NEBL,MSI2,HIF3A,CSGALNACT1,CTNNA2,PTPRZ1,AQP4,TRPS1,RFX4,LSAMP,TNIK,CTNND2,SLC4A4,DCLK2,SOX5,NRG3,ATP1A2
9.307e-05	-9.28	telencephalon development	biological process	GO:0021537	276	6	18204	49	NRG3,ATP1A2,RFX4,DCLK2,SLC1A2,NTRK2
9.591e-05	-9.25	Bile secretion	KEGG pathways	hsa04976	71	4	7161	25	AQP4,ADCY2,ATP1A2,SLC4A4
9.591e-05	-9.25	Bile secretion	KEGG pathways	ko04976	71	4	7161	25	SLC4A4,ATP1A2,ADCY2,AQP4
9.955e-05	-9.21	oesophagus-middle_third-carcinoma-squamous_cell_carcinoma	COSMIC cancer mutations	oesophagus-middle_third-carcinoma-squamous_cell_carcinoma	3531	22	16828	48	CTNND2,RPS6KA2,NAV3,ABLIM1,GPC5,TRPM3,PARD3,DPP10,MACF1,ATP1A2,ADCY2,SOX5,GPM6A,SPON1,TNIK,NEBL,PTPRZ1,SLC4A4,NRG3,HPSE2,FMN2,PAMR1
1.004e-04	-9.21	middle_third	COSMIC cancer mutations	middle_third	3533	22	16828	48	ATP1A2,MACF1,SPON1,SOX5,ADCY2,GPM6A,GPC5,ABLIM1,CTNND2,RPS6KA2,NAV3,DPP10,TRPM3,PARD3,NRG3,HPSE2,PAMR1,FMN2,TNIK,SLC4A4,NEBL,PTPRZ1
1.034e-04	-9.18	negative regulation of amide metabolic process	biological process	GO:0034249	34	3	18204	49	NTRK2,SPON1,CLU
1.112e-04	-9.10	neuron differentiation	biological process	GO:0030182	1081	11	18204	49	CTNNA2,NRCAM,PARD3,NTRK2,DCLK2,GPM6A,CTNND2,TNIK,RORA,BMPR1B,PTPRZ1
1.166e-04	-9.06	brain development	biological process	GO:0007420	724	9	18204	49	NTRK2,DCLK2,SLC1A2,NRCAM,CTNNA2,ATP1A2,NRG3,RORA,RFX4
1.167e-04	-9.06	FRS2 (fibroblast growth factor receptor substrate 2)	protein interactions	10818	98	4	19454	50	SORBS1,PARD3,NTRK2,RPS6KA2
1.261e-04	-8.98	neuron projection	cellular component	GO:0043005	1331	12	19108	50	DTNA,CLU,BMPR1B,PARD3,ATP1A2,CTNND2,NRCAM,GPM6A,CTNNA2,SLC1A2,NTRK2,ADCY2
1.374e-04	-8.89	C11orf52 (chromosome 11 open reading frame 52)	protein interactions	91894	310	6	19454	50	ABLIM1,MACF1,PARD3,TNIK,DTNA,FMN2
1.402e-04	-8.87	humerus	COSMIC cancer mutations	humerus	546	8	16828	48	NKAIN3,GPC5,NEBL,HIF3A,GPM6A,FMN2,SOX5,ADCY2
1.449e-04	-8.84	protein kinase activity	molecular function	GO:0004672	577	8	18094	49	NTRK2,MAPK10,DCLK2,RPS6KA2,MAP3K5,EFEMP1,TNIK,BMPR1B
1.490e-04	-8.81	FLOT1 (flotillin 1)	protein interactions	10211	453	7	19454	50	SORBS1,SOX5,ABLIM1,MACF1,FMN2,PARD3,DTNA
1.504e-04	-8.80	plasma membrane bounded cell projection	cellular component	GO:0120025	2285	16	19108	50	MACF1,ADCY2,NTRK2,CTNNA2,FMN2,GPM6A,NRCAM,SLC1A2,BMPR1B,CLU,DTNA,AQP4,ATP1A2,CTNND2,PARD3,ABLIM1
1.520e-04	-8.79	kidney-carcinoma-papillary_renal_cell_carcinoma	COSMIC cancer mutations	kidney-carcinoma-papillary_renal_cell_carcinoma	6364	31	16828	48	MAP3K5,ABLIM1,GPC5,RPS6KA2,NAV3,NTRK2,TRPM3,NRCAM,PARD3,DCLK2,NRG3,PAMR1,RORA,SLC4A4,BMPR1B,PTPRZ1,ATP1A2,MACF1,SPON1,CPE,SOX5,ATP13A4,ADCY2,CTNND2,CLU,DPP10,HPSE2,RFX4,FMN2,TNIK,PITPNC1
1.520e-04	-8.79	papillary_renal_cell_carcinoma	COSMIC cancer mutations	papillary_renal_cell_carcinoma	6364	31	16828	48	TNIK,PITPNC1,HPSE2,FMN2,RFX4,CTNND2,CLU,DPP10,ATP1A2,MACF1,SPON1,SOX5,CPE,ATP13A4,ADCY2,SLC4A4,BMPR1B,PTPRZ1,DCLK2,NRG3,PAMR1,RORA,GPC5,ABLIM1,NAV3,RPS6KA2,NTRK2,NRCAM,TRPM3,PARD3,MAP3K5
1.612e-04	-8.73	bone	COSMIC cancer mutations	bone	8157	36	16828	48	RORA,GLIS3,PAMR1,LSAMP,SORBS1,DCLK2,NRG3,NEBL,PTPRZ1,SLC4A4,MAP3K5,DTNA,HIF3A,TRPM3,NRCAM,PARD3,NTRK2,NKAIN3,NAV3,TRPS1,GPC5,ABLIM1,FMN2,CSGALNACT1,HPSE2,NPAS3,TNIK,ATP13A4,SOX5,CPE,ADCY2,GPM6A,SPON1,MACF1,ATP1A2,CTNND2
1.687e-04	-8.69	developmental process	biological process	GO:0032502	5716	28	18204	49	EFEMP1,CPE,ABLIM1,NAV3,PARD3,BMPR1B,RORA,GPM6A,SLC1A2,NTRK2,NRCAM,PTPRZ1,TRPS1,RFX4,TNIK,LSAMP,CTNND2,DCLK2,SOX5,ATP1A2,NRG3,FMN2,CLU,NEBL,MSI2,HIF3A,CSGALNACT1,CTNNA2
1.729e-04	-8.66	bone-tibia-other-chondroblastoma	COSMIC cancer mutations	bone-tibia-other-chondroblastoma	98	4	16828	48	CTNND2,NKAIN3,LSAMP,GPM6A
1.730e-04	-8.66	Ser/Thr_kinase_AS	interpro domains	IPR008271	308	6	18521	50	MAPK10,MAP3K5,DCLK2,TNIK,BMPR1B,RPS6KA2
1.929e-04	-8.55	head development	biological process	GO:0060322	774	9	18204	49	RFX4,RORA,SLC1A2,DCLK2,NTRK2,ATP1A2,NRG3,NRCAM,CTNNA2
2.033e-04	-8.50	bone-humerus-other-chondroblastoma	COSMIC cancer mutations	bone-humerus-other-chondroblastoma	301	6	16828	48	FMN2,GPM6A,ADCY2,SOX5,GPC5,NKAIN3
2.075e-04	-8.48	oesophagus-carcinoma	COSMIC cancer mutations	oesophagus-carcinoma	4269	24	16828	48	TNIK,HPSE2,RFX4,FMN2,CSGALNACT1,CTNND2,DPP10,MACF1,ADCY2,SOX5,ATP13A4,GPM6A,PTPRZ1,SLC4A4,SORBS1,NRG3,NAV3,RPS6KA2,TRPS1,TRPM3,NRCAM,PARD3,NTRK2,HIF3A
2.215e-04	-8.42	upper_aerodigestive_tract-larynx-carcinoma-squamous_cell_carcinoma	COSMIC cancer mutations	upper_aerodigestive_tract-larynx-carcinoma-squamous_cell_carcinoma	1946	15	16828	48	TNIK,BMPR1B,NEBL,SLC4A4,NPAS3,RBMS3,HPSE2,FMN2,RORA,MGAT4C,CSGALNACT1,NAV3,MACF1,SOX5,GPM6A
2.241e-04	-8.40	larynx	COSMIC cancer mutations	larynx	1948	15	16828	48	MACF1,GPM6A,SOX5,NAV3,RBMS3,HPSE2,RORA,FMN2,MGAT4C,CSGALNACT1,TNIK,NEBL,BMPR1B,SLC4A4,NPAS3
2.276e-04	-8.39	haematopoietic_and_lymphoid_tissue-lymph_node-lymphoid_neoplasm-diffuse_large_B_cell_lymphoma	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue-lymph_node-lymphoid_neoplasm-diffuse_large_B_cell_lymphoma	748	9	16828	48	DTNA,SOX5,DPP10,NTRK2,NEBL,PARD3,TRPS1,CTNND2,NAV3
2.393e-04	-8.34	angiosarcoma	COSMIC cancer mutations	angiosarcoma	2192	16	16828	48	GPM6A,ADCY2,SOX5,SPON1,PARD3,NTRK2,NKAIN3,SLC1A2,CTNND2,GPC5,FMN2,LSAMP,NRG3,HPSE2,PTPRZ1,NEBL
2.393e-04	-8.34	soft_tissue-blood_vessel-angiosarcoma	COSMIC cancer mutations	soft_tissue-blood_vessel-angiosarcoma	2192	16	16828	48	FMN2,LSAMP,NRG3,HPSE2,PTPRZ1,NEBL,GPM6A,SOX5,ADCY2,SPON1,PARD3,NTRK2,NKAIN3,SLC1A2,CTNND2,GPC5
2.647e-04	-8.24	blood_vessel	COSMIC cancer mutations	blood_vessel	2211	16	16828	48	FMN2,LSAMP,NRG3,HPSE2,NEBL,PTPRZ1,ADCY2,SOX5,GPM6A,SPON1,PARD3,NTRK2,CTNND2,SLC1A2,NKAIN3,GPC5
2.647e-04	-8.24	cell projection	cellular component	GO:0042995	2398	16	19108	50	ADCY2,NTRK2,MACF1,SLC1A2,FMN2,CTNNA2,GPM6A,NRCAM,PARD3,AQP4,ATP1A2,CTNND2,BMPR1B,DTNA,CLU,ABLIM1
2.660e-04	-8.23	cytoskeletal protein binding	molecular function	GO:0008092	989	10	18094	49	CTNNA2,SORBS1,MACF1,CLU,DCLK2,NAV3,NRCAM,NEBL,FMN2,ABLIM1
2.863e-04	-8.16	Prot_kinase_dom	interpro domains	IPR000719	480	7	18521	50	DCLK2,MAP3K5,NTRK2,MAPK10,TNIK,BMPR1B,RPS6KA2
2.911e-04	-8.14	regulation of amyloid-beta formation	biological process	GO:1902003	48	3	18204	49	NTRK2,CLU,SPON1
2.945e-04	-8.13	CXADR (CXADR Ig-like cell adhesion molecule)	protein interactions	1525	357	6	19454	50	MACF1,SORBS1,RPS6KA2,NEBL,PARD3,TNIK
3.047e-04	-8.10	bronchioloalveolar_adenocarcinoma	COSMIC cancer mutations	bronchioloalveolar_adenocarcinoma	778	9	16828	48	ADCY2,SOX5,MAP3K5,DCLK2,BMPR1B,NTRK2,CTNND2,RPS6KA2,TNIK
3.047e-04	-8.10	lung-carcinoma-bronchioloalveolar_adenocarcinoma	COSMIC cancer mutations	lung-carcinoma-bronchioloalveolar_adenocarcinoma	778	9	16828	48	ADCY2,SOX5,MAP3K5,DCLK2,NTRK2,BMPR1B,TNIK,CTNND2,RPS6KA2
3.162e-04	-8.06	EPB41L4A (erythrocyte membrane protein band 4.1 like 4A)	protein interactions	64097	127	4	19454	50	MACF1,DTNA,PARD3,ABLIM1
3.251e-04	-8.03	synapse	cellular component	GO:0045202	1473	12	19108	50	RPS6KA2,NRCAM,GPM6A,SLC1A2,TNIK,NTRK2,NRG3,PTPRZ1,DTNA,CLU,CTNND2,ATP1A2
3.432e-04	-7.98	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm	7307	33	16828	48	CSGALNACT1,MGAT4C,FMN2,RFX4,HPSE2,TNIK,SPON1,GPM6A,ATP13A4,CPE,ADCY2,SOX5,MACF1,DPP10,CLU,CTNND2,PAMR1,RORA,GLIS3,NRG3,LSAMP,PTPRZ1,BMPR1B,NEBL,MAP3K5,NTRK2,EFEMP1,PARD3,GPC5,ABLIM1,NKAIN3,NAV3,SLC1A2
3.702e-04	-7.90	EZR (ezrin)	protein interactions	7430	526	7	19454	50	DTNA,TNIK,NEBL,MAPK10,MACF1,ABLIM1,SORBS1
3.708e-04	-7.90	protein phosphorylation	biological process	GO:0006468	503	7	18204	49	TNIK,EFEMP1,MAPK10,BMPR1B,MAP3K5,NTRK2,RPS6KA2
3.740e-04	-7.89	haematopoietic_and_lymphoid_tissue-lymph_node-lymphoid_neoplasm-mantle_cell_lymphoma	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue-lymph_node-lymphoid_neoplasm-mantle_cell_lymphoma	476	7	16828	48	NRG3,GPC5,LSAMP,CTNND2,GPM6A,ATP13A4,TRPM3
3.883e-04	-7.85	skin-scalp-carcinoma-squamous_cell_carcinoma	COSMIC cancer mutations	skin-scalp-carcinoma-squamous_cell_carcinoma	1596	13	16828	48	SOX5,ATP13A4,ATP1A2,MACF1,NRCAM,GPC5,TRPS1,NAV3,RORA,RBMS3,LSAMP,SLC4A4,PTPRZ1
3.885e-04	-7.85	central_nervous_system-brainstem-glioma-astrocytoma_Grade_IV	COSMIC cancer mutations	central_nervous_system-brainstem-glioma-astrocytoma_Grade_IV	2531	17	16828	48	LSAMP,HPSE2,NRG3,RORA,FMN2,TNIK,PTPRZ1,ADCY2,SOX5,CPE,ATP13A4,GPM6A,SPON1,CTNND2,NKAIN3,GPC5,PARD3
3.923e-04	-7.84	cell junction	cellular component	GO:0030054	2224	15	19108	50	RPS6KA2,CTNNA2,GPM6A,NRCAM,SLC1A2,TNIK,NRG3,NTRK2,PTPRZ1,CLU,SORBS1,DTNA,CTNND2,ATP1A2,PARD3
3.988e-04	-7.83	NTRK2 (neurotrophic receptor tyrosine kinase 2)	protein interactions	4915	135	4	19454	50	DTNA,NTRK2,PARD3,ABLIM1
4.290e-04	-7.75	testis-germ_cell_tumour-non_seminoma	COSMIC cancer mutations	testis-germ_cell_tumour-non_seminoma	487	7	16828	48	TNIK,RPS6KA2,NTRK2,BMPR1B,DCLK2,MACF1,MAP3K5
4.337e-04	-7.74	phosphorus metabolic process	biological process	GO:0006793	1707	13	18204	49	ATP1A2,RPS6KA2,DCLK2,TNIK,MAPK10,EFEMP1,PTPRZ1,MAP3K5,CSGALNACT1,NTRK2,RORA,BMPR1B,ADCY2
4.357e-04	-7.74	regulation of amyloid precursor protein catabolic process	biological process	GO:1902991	55	3	18204	49	NTRK2,SPON1,CLU
4.561e-04	-7.69	non_seminoma	COSMIC cancer mutations	non_seminoma	492	7	16828	48	MACF1,RPS6KA2,DCLK2,TNIK,MAP3K5,BMPR1B,NTRK2
4.667e-04	-7.67	phosphotransferase activity, alcohol group as acceptor	molecular function	GO:0016773	686	8	18094	49	NTRK2,MAPK10,DCLK2,MAP3K5,RPS6KA2,EFEMP1,BMPR1B,TNIK
4.796e-04	-7.64	neuron projection development	biological process	GO:0031175	693	8	18204	49	BMPR1B,GPM6A,PTPRZ1,CTNND2,NRCAM,TNIK,CTNNA2,PARD3
4.797e-04	-7.64	Kinase-like_dom_sf	interpro domains	IPR011009	523	7	18521	50	TNIK,BMPR1B,MAPK10,DCLK2,MAP3K5,NTRK2,RPS6KA2
4.928e-04	-7.62	NAKATPASE	prints domains	PR00121	9	2	5227	20	ATP13A4,ATP1A2
5.005e-04	-7.60	brainstem	COSMIC cancer mutations	brainstem	3102	19	16828	48	NPAS3,PTPRZ1,TNIK,FMN2,RORA,NRG3,HPSE2,LSAMP,PARD3,GPC5,NKAIN3,CTNND2,SLC1A2,SPON1,GPM6A,ATP13A4,ADCY2,CPE,SOX5
5.017e-04	-7.60	haematopoietic_and_lymphoid_tissue	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue	14368	48	16828	48	SLC4A4,BMPR1B,NRG3,DCLK2,PAMR1,RORA,GPC5,TRPS1,NAV3,NTRK2,EFEMP1,PARD3,TRPM3,HIF3A,MSI2,DTNA,TNIK,NPAS3,HPSE2,RBMS3,CSGALNACT1,ATP1A2,SPON1,GPM6A,ATP13A4,ADCY2,PTPRZ1,NEBL,SORBS1,LSAMP,GLIS3,ABLIM1,NKAIN3,RPS6KA2,SLC1A2,NRCAM,AQP4,MAP3K5,PITPNC1,MGAT4C,RFX4,FMN2,CLU,CTNND2,DPP10,MACF1,CPE,SOX5
5.099e-04	-7.58	nasopharyngeal_carcinoma	COSMIC cancer mutations	nasopharyngeal_carcinoma	1425	12	16828	48	FMN2,RFX4,SLC4A4,PITPNC1,ATP1A2,ATP13A4,CLU,RPS6KA2,CTNND2,SLC1A2,NTRK2,DPP10
5.099e-04	-7.58	upper_aerodigestive_tract-pharynx-carcinoma-nasopharyngeal_carcinoma	COSMIC cancer mutations	upper_aerodigestive_tract-pharynx-carcinoma-nasopharyngeal_carcinoma	1425	12	16828	48	SLC4A4,PITPNC1,FMN2,RFX4,NTRK2,DPP10,CLU,RPS6KA2,SLC1A2,CTNND2,ATP13A4,ATP1A2
5.100e-04	-7.58	Protein_kinase_ATP_BS	interpro domains	IPR017441	377	6	18521	50	RPS6KA2,BMPR1B,TNIK,NTRK2,MAP3K5,DCLK2
5.158e-04	-7.57	tibia	COSMIC cancer mutations	tibia	836	9	16828	48	CTNND2,NKAIN3,ABLIM1,TNIK,TRPM3,MACF1,LSAMP,CPE,GPM6A
5.507e-04	-7.50	cell development	biological process	GO:0048468	2236	15	18204	49	NRCAM,CTNNA2,GPM6A,MSI2,NTRK2,RORA,CLU,NEBL,BMPR1B,PARD3,FMN2,DCLK2,CTNND2,TNIK,PTPRZ1
5.630e-04	-7.48	transmission of nerve impulse	biological process	GO:0019226	60	3	18204	49	NTRK2,NRCAM,ATP1A2
5.776e-04	-7.46	PLXNA4 (plexin A4)	protein interactions	91584	14	2	19454	50	CLU,GPM6A
5.887e-04	-7.44	autonomic_ganglia-neuroblastoma	COSMIC cancer mutations	autonomic_ganglia-neuroblastoma	3970	22	16828	48	RFX4,FMN2,NPAS3,PITPNC1,TNIK,GPM6A,ADCY2,ATP1A2,MACF1,DPP10,CTNND2,GLIS3,SLC4A4,PTPRZ1,NEBL,HIF3A,AQP4,NTRK2,PARD3,TRPS1,NAV3,SLC1A2
5.909e-04	-7.43	neuroblastoma	COSMIC cancer mutations	neuroblastoma	3971	22	16828	48	GPM6A,ADCY2,ATP1A2,HIF3A,MACF1,AQP4,NTRK2,DPP10,PARD3,TRPS1,NAV3,SLC1A2,CTNND2,GLIS3,RFX4,FMN2,SLC4A4,NPAS3,PTPRZ1,NEBL,PITPNC1,TNIK
6.050e-04	-7.41	PROTEIN_KINASE_ST	prosite domains	PS00108	308	6	12186	42	DCLK2,RPS6KA2,MAPK10,BMPR1B,MAP3K5,TNIK
6.100e-04	-7.40	NS-malignant_melanoma	COSMIC cancer mutations	NS-malignant_melanoma	3420	20	16828	48	SPON1,ATP13A4,ADCY2,MAP3K5,ATP1A2,MACF1,EFEMP1,PARD3,TRPM3,GPC5,RPS6KA2,CTNND2,MGAT4C,GLIS3,FMN2,RFX4,NRG3,PTPRZ1,PITPNC1,NEBL
6.321e-04	-7.37	Transferase(Phosphotransferase) domain 1	gene3d domains	1.10.510.10	490	7	14470	44	DCLK2,BMPR1B,RPS6KA2,MAP3K5,MAPK10,NTRK2,TNIK
6.327e-04	-7.37	sodium ion export across plasma membrane	biological process	GO:0036376	14	2	18204	49	ATP1A2,SLC4A4
6.557e-04	-7.33	soft_tissue	COSMIC cancer mutations	soft_tissue	5828	28	16828	48	FMN2,HPSE2,NPAS3,SPON1,GPM6A,ADCY2,SOX5,MACF1,DPP10,CLU,CTNND2,PAMR1,GLIS3,RORA,NRG3,LSAMP,SORBS1,PTPRZ1,NEBL,MAP3K5,AQP4,NTRK2,PARD3,TRPM3,GPC5,TRPS1,NKAIN3,SLC1A2
6.654e-04	-7.32	TIAM2 (TIAM Rac1 associated GEF 2)	protein interactions	26230	15	2	19454	50	PARD3,TNIK
6.654e-04	-7.32	RNASE13 (ribonuclease A family member 13 (inactive))	protein interactions	440163	15	2	19454	50	CLU,CPE
6.693e-04	-7.31	autonomic_ganglia	COSMIC cancer mutations	autonomic_ganglia	4005	22	16828	48	DPP10,CTNND2,GPM6A,ADCY2,MACF1,ATP1A2,PITPNC1,NPAS3,TNIK,RFX4,FMN2,PARD3,NTRK2,NAV3,SLC1A2,TRPS1,HIF3A,AQP4,PTPRZ1,NEBL,SLC4A4,GLIS3
6.697e-04	-7.31	phosphorylation	biological process	GO:0016310	729	8	18204	49	TNIK,EFEMP1,BMPR1B,MAPK10,MAP3K5,DCLK2,RPS6KA2,NTRK2
6.818e-04	-7.29	mast_cell_neoplasm	COSMIC cancer mutations	mast_cell_neoplasm	248	5	16828	48	GPC5,NRG3,HPSE2,NPAS3,ADCY2
6.818e-04	-7.29	haematopoietic_and_lymphoid_tissue-haematopoietic_neoplasm-mast_cell_neoplasm	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue-haematopoietic_neoplasm-mast_cell_neoplasm	248	5	16828	48	ADCY2,NPAS3,GPC5,HPSE2,NRG3
7.001e-04	-7.26	Neurotrophin signaling pathway	KEGG pathways	hsa04722	119	4	7161	25	RPS6KA2,MAP3K5,NTRK2,MAPK10
7.001e-04	-7.26	Neurotrophin signaling pathway	KEGG pathways	ko04722	119	4	7161	25	MAPK10,NTRK2,MAP3K5,RPS6KA2
7.496e-04	-7.20	main axon	cellular component	GO:0044304	68	3	19108	50	NRCAM,SLC1A2,PARD3
7.564e-04	-7.19	forebrain development	biological process	GO:0030900	408	6	18204	49	NRG3,ATP1A2,NTRK2,DCLK2,SLC1A2,RFX4
7.592e-04	-7.18	CNTNAP2 (contactin associated protein 2)	protein interactions	26047	16	2	19454	50	MACF1,CPE
7.616e-04	-7.18	kinase activity	molecular function	GO:0016301	739	8	18094	49	DCLK2,NTRK2,MAPK10,EFEMP1,TNIK,BMPR1B,RPS6KA2,MAP3K5
7.661e-04	-7.17	stomach-carcinoma-intestinal_adenocarcinoma	COSMIC cancer mutations	stomach-carcinoma-intestinal_adenocarcinoma	7225	32	16828	48	LSAMP,DCLK2,NRG3,RORA,NEBL,PTPRZ1,SLC4A4,AQP4,MAP3K5,SLC1A2,RPS6KA2,NAV3,TRPS1,NRCAM,TRPM3,PARD3,NTRK2,HPSE2,RFX4,FMN2,CSGALNACT1,PITPNC1,NPAS3,MACF1,ATP1A2,SOX5,ADCY2,ATP13A4,SPON1,CTNND2,CLU,DPP10
7.661e-04	-7.17	intestinal_adenocarcinoma	COSMIC cancer mutations	intestinal_adenocarcinoma	7225	32	16828	48	CLU,CTNND2,DPP10,ATP1A2,MACF1,SPON1,ADCY2,ATP13A4,SOX5,NPAS3,PITPNC1,HPSE2,CSGALNACT1,RFX4,FMN2,TRPS1,NAV3,RPS6KA2,SLC1A2,NTRK2,PARD3,TRPM3,NRCAM,AQP4,MAP3K5,SLC4A4,PTPRZ1,NEBL,NRG3,DCLK2,LSAMP,RORA
8.042e-04	-7.13	upper_aerodigestive_tract	COSMIC cancer mutations	upper_aerodigestive_tract	13181	46	16828	48	CSGALNACT1,RBMS3,HPSE2,NPAS3,TNIK,GPM6A,ATP13A4,ADCY2,SPON1,ATP1A2,RORA,PAMR1,NRG3,DCLK2,BMPR1B,SLC4A4,MSI2,DTNA,HIF3A,PARD3,TRPM3,NTRK2,EFEMP1,NAV3,GPC5,TRPS1,RFX4,FMN2,MGAT4C,PITPNC1,SOX5,MACF1,DPP10,CLU,CTNND2,GLIS3,SORBS1,LSAMP,PTPRZ1,NEBL,MAP3K5,NRCAM,NKAIN3,RPS6KA2,SLC1A2,ABLIM1
8.074e-04	-7.12	ANK2 (ankyrin 2)	protein interactions	287	71	3	19454	50	GPM6A,TNIK,NRCAM
8.090e-04	-7.12	animal organ development	biological process	GO:0048513	2846	17	18204	49	CTNNA2,NRCAM,CSGALNACT1,NTRK2,GPM6A,SLC1A2,NEBL,RORA,BMPR1B,ATP1A2,NRG3,SOX5,DCLK2,CPE,ABLIM1,RFX4,EFEMP1
8.233e-04	-7.10	pancreas-carcinoid-endocrine_tumour	COSMIC cancer mutations	pancreas-carcinoid-endocrine_tumour	7250	32	16828	48	HPSE2,CSGALNACT1,RFX4,FMN2,CTNND2,CLU,DPP10,ATP1A2,MACF1,SPON1,SOX5,ATP13A4,CPE,ADCY2,GPM6A,SLC4A4,NEBL,BMPR1B,NRG3,LSAMP,PAMR1,GLIS3,RORA,GPC5,ABLIM1,SLC1A2,NKAIN3,EFEMP1,NTRK2,NRCAM,PARD3,MAP3K5
8.315e-04	-7.09	asymmetric cell division	biological process	GO:0008356	16	2	18204	49	SOX5,PARD3
8.364e-04	-7.09	kidney-Wilms_tumour	COSMIC cancer mutations	kidney-Wilms_tumour	545	7	16828	48	DCLK2,TNIK,RPS6KA2,NTRK2,FMN2,BMPR1B,MAP3K5
8.443e-04	-7.08	plasma membrane bounded cell projection organization	biological process	GO:0120036	1152	10	18204	49	PARD3,NRCAM,CTNNA2,GPM6A,ABLIM1,RFX4,TNIK,CTNND2,PTPRZ1,BMPR1B
8.454e-04	-7.08	Wilms_tumour	COSMIC cancer mutations	Wilms_tumour	546	7	16828	48	MAP3K5,FMN2,DCLK2,NTRK2,BMPR1B,TNIK,RPS6KA2
9.082e-04	-7.00	breast-carcinoma-basal_(triple-negative)_carcinoma	COSMIC cancer mutations	breast-carcinoma-basal_(triple-negative)_carcinoma	2981	18	16828	48	NTRK2,DPP10,PARD3,TRPM3,NRCAM,RPS6KA2,MSI2,MAP3K5,ADCY2,ATP1A2,HIF3A,MACF1,SLC4A4,NPAS3,NEBL,BMPR1B,FMN2,NRG3
9.082e-04	-7.00	basal_(triple-negative)_carcinoma	COSMIC cancer mutations	basal_(triple-negative)_carcinoma	2981	18	16828	48	NRG3,FMN2,BMPR1B,NEBL,SLC4A4,NPAS3,MACF1,HIF3A,ATP1A2,MAP3K5,ADCY2,MSI2,RPS6KA2,TRPM3,NRCAM,PARD3,DPP10,NTRK2
9.860e-04	-6.92	cell junction assembly	biological process	GO:0034329	285	5	18204	49	GPM6A,SORBS1,NRG3,PARD3,NRCAM
1.000e-03	-6.91	protein serine/threonine kinase activity	molecular function	GO:0004674	428	6	18094	49	DCLK2,MAPK10,TNIK,BMPR1B,RPS6KA2,MAP3K5
1.003e-03	-6.90	testis	COSMIC cancer mutations	testis	733	8	16828	48	BMPR1B,NTRK2,RPS6KA2,TNIK,TRPS1,MAP3K5,MACF1,DCLK2
1.022e-03	-6.89	ADGRL2 (adhesion G protein-coupled receptor L2)	protein interactions	23266	77	3	19454	50	PARD3,RPS6KA2,NTRK2
1.063e-03	-6.85	ATPase_P-typ_cation-transptr_N	interpro domains	IPR004014	18	2	18521	50	ATP1A2,ATP13A4
1.067e-03	-6.84	mucosal	COSMIC cancer mutations	mucosal	2009	14	16828	48	CTNND2,ABLIM1,PARD3,EFEMP1,ATP1A2,CPE,ATP13A4,BMPR1B,NEBL,SORBS1,NRG3,RORA,FMN2,MGAT4C
1.067e-03	-6.84	skin-mucosal-malignant_melanoma	COSMIC cancer mutations	skin-mucosal-malignant_melanoma	2009	14	16828	48	NEBL,BMPR1B,NRG3,SORBS1,MGAT4C,RORA,FMN2,ABLIM1,CTNND2,EFEMP1,PARD3,ATP1A2,ATP13A4,CPE
1.075e-03	-6.84	actin binding	molecular function	GO:0003779	434	6	18094	49	CTNNA2,MACF1,SORBS1,NEBL,FMN2,ABLIM1
1.080e-03	-6.83	prostate	COSMIC cancer mutations	prostate	13883	47	16828	48	PITPNC1,FMN2,RFX4,MGAT4C,DPP10,CLU,CTNND2,SOX5,CPE,MACF1,PTPRZ1,NEBL,GLIS3,LSAMP,SORBS1,NRCAM,RPS6KA2,NKAIN3,SLC1A2,ABLIM1,MAP3K5,AQP4,NPAS3,TNIK,CSGALNACT1,HPSE2,GPM6A,ATP13A4,ADCY2,SPON1,ATP1A2,BMPR1B,SLC4A4,RORA,PAMR1,NRG3,DCLK2,PARD3,TRPM3,NTRK2,EFEMP1,NAV3,TRPS1,GPC5,MSI2,DTNA,HIF3A
1.088e-03	-6.82	dendrite	cellular component	GO:0030425	620	7	19108	50	ATP1A2,CTNND2,NTRK2,ADCY2,CLU,BMPR1B,GPM6A
1.105e-03	-6.81	Cation_ATPase_N	pfam domains	PF00690	18	2	17795	49	ATP1A2,ATP13A4
1.108e-03	-6.80	dendritic tree	cellular component	GO:0097447	622	7	19108	50	GPM6A,NTRK2,CTNND2,ATP1A2,ADCY2,CLU,BMPR1B
1.115e-03	-6.80	astrocyte projection	cellular component	GO:0097449	19	2	19108	50	SLC1A2,AQP4
1.137e-03	-6.78	animal organ morphogenesis	biological process	GO:0009887	988	9	18204	49	NTRK2,SOX5,CTNNA2,NRG3,CSGALNACT1,EFEMP1,BMPR1B,CPE,ABLIM1
1.147e-03	-6.77	PROTEIN_KINASE_DOM	prosite domains	PS50011	480	7	12186	42	RPS6KA2,BMPR1B,MAP3K5,TNIK,MAPK10,NTRK2,DCLK2
1.154e-03	-6.76	cell projection organization	biological process	GO:0030030	1200	10	18204	49	CTNND2,TNIK,RFX4,ABLIM1,BMPR1B,PTPRZ1,CTNNA2,NRCAM,PARD3,GPM6A
1.158e-03	-6.76	cell morphogenesis involved in neuron differentiation	biological process	GO:0048667	443	6	18204	49	BMPR1B,PTPRZ1,NRCAM,CTNNA2,CTNND2,PARD3
1.179e-03	-6.74	cartilage condensation	biological process	GO:0001502	19	2	18204	49	SOX5,BMPR1B
1.186e-03	-6.74	PAS_fold	interpro domains	IPR013767	19	2	18521	50	NPAS3,HIF3A
1.233e-03	-6.70	PAS	pfam domains	PF00989	19	2	17795	49	NPAS3,HIF3A
1.246e-03	-6.69	urinary_tract-bladder-carcinoma-transitional_cell_carcinoma	COSMIC cancer mutations	urinary_tract-bladder-carcinoma-transitional_cell_carcinoma	6040	28	16828	48	HPSE2,RFX4,FMN2,MGAT4C,CLU,DPP10,MACF1,ATP1A2,ATP13A4,ADCY2,GPM6A,NEBL,PTPRZ1,SLC4A4,SORBS1,NRG3,GLIS3,NAV3,TRPS1,ABLIM1,GPC5,TRPM3,NRCAM,PARD3,NTRK2,HIF3A,MAP3K5,DTNA
1.254e-03	-6.68	transitional_cell_carcinoma	COSMIC cancer mutations	transitional_cell_carcinoma	6042	28	16828	48	FMN2,RFX4,MGAT4C,HPSE2,DPP10,CLU,ADCY2,ATP13A4,GPM6A,MACF1,ATP1A2,NEBL,PTPRZ1,SLC4A4,GLIS3,SORBS1,NRG3,NRCAM,TRPM3,PARD3,NTRK2,NAV3,GPC5,ABLIM1,TRPS1,MAP3K5,DTNA,HIF3A
1.274e-03	-6.67	central nervous system neuron differentiation	biological process	GO:0021953	176	4	18204	49	NTRK2,BMPR1B,DCLK2,RORA
1.307e-03	-6.64	positive regulation of chondrocyte differentiation	biological process	GO:0032332	20	2	18204	49	SOX5,BMPR1B
1.318e-03	-6.63	TENM1 (teneurin transmembrane protein 1)	protein interactions	10178	21	2	19454	50	SORBS1,MACF1
1.325e-03	-6.63	positive regulation of cellular process	biological process	GO:0048522	5719	26	18204	49	SLC4A4,SOX5,FMN2,GPC5,PTPRZ1,GLIS3,RFX4,MACF1,TNIK,NPAS3,DPP10,SORBS1,CLU,RPS6KA2,NAV3,PARD3,GPM6A,SLC1A2,NTRK2,HPSE2,MAP3K5,NRCAM,SPON1,BMPR1B,RORA,RBMS3
1.330e-03	-6.62	kidney-carcinoma-chromophobe_renal_cell_carcinoma	COSMIC cancer mutations	kidney-carcinoma-chromophobe_renal_cell_carcinoma	430	6	16828	48	BMPR1B,NTRK2,RPS6KA2,TNIK,MAP3K5,DCLK2
1.330e-03	-6.62	chromophobe_renal_cell_carcinoma	COSMIC cancer mutations	chromophobe_renal_cell_carcinoma	430	6	16828	48	MAP3K5,BMPR1B,NTRK2,RPS6KA2,DCLK2,TNIK
1.343e-03	-6.61	phosphate-containing compound metabolic process	biological process	GO:0006796	1681	12	18204	49	ATP1A2,RPS6KA2,DCLK2,TNIK,EFEMP1,MAPK10,PTPRZ1,MAP3K5,NTRK2,RORA,BMPR1B,ADCY2
1.349e-03	-6.61	regulation of amide metabolic process	biological process	GO:0034248	81	3	18204	49	CLU,SPON1,NTRK2
1.373e-03	-6.59	transmembrane receptor protein kinase activity	molecular function	GO:0019199	81	3	18094	49	BMPR1B,EFEMP1,NTRK2
1.429e-03	-6.55	axon	cellular component	GO:0030424	650	7	19108	50	NRCAM,GPM6A,CTNNA2,SLC1A2,DTNA,NTRK2,PARD3
1.443e-03	-6.54	cell aggregation	biological process	GO:0098743	21	2	18204	49	SOX5,BMPR1B
1.443e-03	-6.54	retinal ganglion cell axon guidance	biological process	GO:0031290	21	2	18204	49	BMPR1B,NRCAM
1.463e-03	-6.53	upper_aerodigestive_tract-mouth-carcinoma	COSMIC cancer mutations	upper_aerodigestive_tract-mouth-carcinoma	6426	29	16828	48	SLC4A4,PAMR1,RORA,NRG3,SORBS1,EFEMP1,PARD3,NRCAM,TRPM3,TRPS1,GPC5,ABLIM1,NAV3,SLC1A2,MAP3K5,HIF3A,NPAS3,PITPNC1,MGAT4C,RFX4,FMN2,HPSE2,CLU,CTNND2,SPON1,GPM6A,SOX5,ADCY2,MACF1
1.468e-03	-6.52	adherens junction	cellular component	GO:0005912	188	4	19108	50	PARD3,CTNND2,SORBS1,CTNNA2
1.481e-03	-6.52	contractile actin filament bundle	cellular component	GO:0097517	86	3	19108	50	SORBS1,NEBL,ABLIM1
1.481e-03	-6.52	stress fiber	cellular component	GO:0001725	86	3	19108	50	SORBS1,ABLIM1,NEBL
1.484e-03	-6.51	ROR2 (receptor tyrosine kinase like orphan receptor 2)	protein interactions	4920	327	5	19454	50	SORBS1,PARD3,TNIK,DTNA,RPS6KA2
1.517e-03	-6.49	plasma membrane region	cellular component	GO:0098590	1278	10	19108	50	GPM6A,NRCAM,SLC1A2,SLC4A4,TNIK,SORBS1,MACF1,AQP4,ATP1A2,PARD3
1.548e-03	-6.47	SFN (stratifin)	protein interactions	2810	671	7	19454	50	MACF1,MAP3K5,SORBS1,ABLIM1,PARD3,TNIK,FMN2
1.550e-03	-6.47	Cation_ATPase_N	smart domains	SM00831	16	2	9717	36	ATP1A2,ATP13A4
1.550e-03	-6.47	oligodendrocyte differentiation	biological process	GO:0048709	85	3	18204	49	CLU,PTPRZ1,NTRK2
1.571e-03	-6.46	ATP binding	molecular function	GO:0005524	1467	11	18094	49	BMPR1B,DCLK2,NAV3,MAP3K5,ATP13A4,RPS6KA2,ATP1A2,TNIK,NTRK2,MAPK10,ADCY2
1.577e-03	-6.45	ductolobular_carcinoma	COSMIC cancer mutations	ductolobular_carcinoma	1619	12	16828	48	PTPRZ1,RORA,FMN2,SORBS1,DPP10,NRCAM,ABLIM1,CTNND2,NAV3,DTNA,CPE,MACF1
1.577e-03	-6.45	breast-carcinoma-ductolobular_carcinoma	COSMIC cancer mutations	breast-carcinoma-ductolobular_carcinoma	1619	12	16828	48	NAV3,CTNND2,ABLIM1,PTPRZ1,NRCAM,DPP10,SORBS1,MACF1,RORA,FMN2,CPE,DTNA
1.582e-03	-6.45	TIMM10B (translocase of inner mitochondrial membrane 10B)	protein interactions	26515	23	2	19454	50	HPSE2,MSI2
1.584e-03	-6.45	S_TKc	smart domains	SM00220	348	6	9717	36	RPS6KA2,MAP3K5,DCLK2,BMPR1B,MAPK10,TNIK
1.603e-03	-6.44	transport across blood-brain barrier	biological process	GO:0150104	86	3	18204	49	ATP1A2,SLC4A4,SLC1A2
1.603e-03	-6.44	vascular transport	biological process	GO:0010232	86	3	18204	49	SLC1A2,SLC4A4,ATP1A2
1.701e-03	-6.38	adenoma	COSMIC cancer mutations	adenoma	2873	17	16828	48	NPAS3,PTPRZ1,NEBL,BMPR1B,HPSE2,DCLK2,NTRK2,PARD3,TRPM3,GPC5,NAV3,CTNND2,GPM6A,SOX5,ADCY2,HIF3A,MACF1
1.722e-03	-6.36	PROTEIN_KINASE_ATP	prosite domains	PS00107	377	6	12186	42	DCLK2,NTRK2,TNIK,MAP3K5,BMPR1B,RPS6KA2
1.782e-03	-6.33	HS-GAG degradation	REACTOME pathways	R-HSA-2024096	21	2	10285	31	GPC5,HPSE2
1.787e-03	-6.33	Insulin Signaling	WikiPathways	WP481	161	4	5310	18	MAPK10,RPS6KA2,MAP3K5,SORBS1
1.793e-03	-6.32	ovary-carcinoma-mucinous_carcinoma	COSMIC cancer mutations	ovary-carcinoma-mucinous_carcinoma	456	6	16828	48	NTRK2,BMPR1B,TNIK,RPS6KA2,MAP3K5,DCLK2
1.797e-03	-6.32	actomyosin	cellular component	GO:0042641	92	3	19108	50	SORBS1,ABLIM1,NEBL
1.824e-03	-6.31	adrenal_gland	COSMIC cancer mutations	adrenal_gland	2628	16	16828	48	NRG3,HPSE2,FMN2,RFX4,CSGALNACT1,PTPRZ1,ATP1A2,SOX5,MAP3K5,ADCY2,CTNND2,SLC1A2,NRCAM,TRPM3,EFEMP1,NTRK2
1.833e-03	-6.30	mucinous_carcinoma	COSMIC cancer mutations	mucinous_carcinoma	458	6	16828	48	RPS6KA2,DCLK2,TNIK,BMPR1B,MAP3K5,NTRK2
1.909e-03	-6.26	P-type ion transporter activity	molecular function	GO:0015662	24	2	18094	49	ATP1A2,ATP13A4
1.909e-03	-6.26	P-type transmembrane transporter activity	molecular function	GO:0140358	24	2	18094	49	ATP13A4,ATP1A2
1.913e-03	-6.26	Adherens junction	KEGG pathways	ko04520	72	3	7161	25	CTNNA2,PARD3,SORBS1
1.913e-03	-6.26	Adherens junction	KEGG pathways	hsa04520	72	3	7161	25	PARD3,SORBS1,CTNNA2
1.913e-03	-6.26	human chr4q31.23-q31.3	chromosome location	human chr4q31.23-q31.3	1	1	26134	50	DCLK2
1.913e-03	-6.26	human chr10p11.22-p11.21	chromosome location	human chr10p11.22-p11.21	1	1	26134	50	PARD3
1.913e-03	-6.26	human chr9q21.12-q21.13	chromosome location	human chr9q21.12-q21.13	1	1	26134	50	TRPM3
1.913e-03	-6.26	human chr12q21.31-q21.32	chromosome location	human chr12q21.31-q21.32	1	1	26134	50	MGAT4C
1.913e-03	-6.26	human chr3q26.2-q26.31	chromosome location	human chr3q26.2-q26.31	1	1	26134	50	TNIK
1.957e-03	-6.24	ovary-carcinoma-endometrioid_carcinoma	COSMIC cancer mutations	ovary-carcinoma-endometrioid_carcinoma	464	6	16828	48	NTRK2,BMPR1B,MAP3K5,DCLK2,TNIK,RPS6KA2
1.970e-03	-6.23	skin-trunk-malignant_melanoma	COSMIC cancer mutations	skin-trunk-malignant_melanoma	2647	16	16828	48	ATP1A2,ATP13A4,SOX5,MAP3K5,TRPS1,RPS6KA2,CTNND2,DPP10,PARD3,NRCAM,HPSE2,NRG3,LSAMP,MGAT4C,PTPRZ1,NEBL
2.023e-03	-6.20	NRCAM (neuronal cell adhesion molecule)	protein interactions	4897	26	2	19454	50	MACF1,NRCAM
2.030e-03	-6.20	actin filament bundle	cellular component	GO:0032432	96	3	19108	50	SORBS1,NEBL,ABLIM1
2.047e-03	-6.19	positive regulation of amyloid precursor protein catabolic process	biological process	GO:1902993	25	2	18204	49	SPON1,CLU
2.112e-03	-6.16	cell surface	cellular component	GO:0009986	896	8	19108	50	MAP3K5,ATP1A2,AQP4,CLU,SLC4A4,SLC1A2,GPC5,NRCAM
2.176e-03	-6.13	adenyl ribonucleotide binding	molecular function	GO:0032559	1528	11	18094	49	DCLK2,NAV3,BMPR1B,ADCY2,MAPK10,NTRK2,TNIK,ATP1A2,MAP3K5,RPS6KA2,ATP13A4
2.181e-03	-6.13	HPCAL4 (hippocalcin like 4)	protein interactions	51440	27	2	19454	50	GPM6A,AQP4
2.181e-03	-6.13	KCNJ12 (potassium inwardly rectifying channel subfamily J member 12)	protein interactions	3768	27	2	19454	50	DTNA,ABLIM1
2.185e-03	-6.13	LYN (LYN proto-oncogene, Src family tyrosine kinase)	protein interactions	4067	713	7	19454	50	ABLIM1,MACF1,FMN2,TNIK,MSI2,PARD3,DTNA
2.265e-03	-6.09	testis-germ_cell_tumour-seminoma	COSMIC cancer mutations	testis-germ_cell_tumour-seminoma	648	7	16828	48	RPS6KA2,TRPS1,TNIK,BMPR1B,NTRK2,DCLK2,MAP3K5
2.272e-03	-6.09	actin cytoskeleton	cellular component	GO:0015629	520	6	19108	50	ABLIM1,NEBL,CTNNA2,FMN2,MACF1,SORBS1
2.359e-03	-6.05	MAPK (JNK) signaling	KEGG pathways	hsa_M00688	21	2	7161	25	MAPK10,MAP3K5
2.359e-03	-6.05	MAPK (JNK) signaling	KEGG pathways	M00688	21	2	7161	25	MAPK10,MAP3K5
2.393e-03	-6.04	diffuse_adenocarcinoma	COSMIC cancer mutations	diffuse_adenocarcinoma	4383	22	16828	48	RFX4,FMN2,MGAT4C,MACF1,ATP1A2,GPM6A,SOX5,ADCY2,SPON1,CLU,CTNND2,DPP10,NRG3,GLIS3,PTPRZ1,HIF3A,MAP3K5,DTNA,ABLIM1,TRPS1,PARD3,TRPM3
2.393e-03	-6.04	stomach-carcinoma-diffuse_adenocarcinoma	COSMIC cancer mutations	stomach-carcinoma-diffuse_adenocarcinoma	4383	22	16828	48	DPP10,CLU,CTNND2,SPON1,GPM6A,ADCY2,SOX5,ATP1A2,MACF1,MGAT4C,RFX4,FMN2,PARD3,TRPM3,TRPS1,ABLIM1,DTNA,MAP3K5,HIF3A,PTPRZ1,GLIS3,NRG3
2.415e-03	-6.03	poly(U) RNA binding	molecular function	GO:0008266	27	2	18094	49	MSI2,RBMS3
2.424e-03	-6.02	HUNK (hormonally up-regulated Neu-associated kinase)	protein interactions	30811	104	3	19454	50	SORBS1,ABLIM1,CLU
2.455e-03	-6.01	NTRK3 (neurotrophic receptor tyrosine kinase 3)	protein interactions	4916	367	5	19454	50	NTRK2,PARD3,ABLIM1,TNIK,CLU
2.499e-03	-5.99	stomach-adenocarcinoma	COSMIC cancer mutations	stomach-adenocarcinoma	4101	21	16828	48	SLC4A4,NEBL,NRG3,CSGALNACT1,MGAT4C,PAMR1,RORA,FMN2,RFX4,GPC5,TRPS1,ABLIM1,NAV3,SLC1A2,CTNND2,PARD3,NRCAM,ATP1A2,MACF1,MAP3K5,ATP13A4
2.526e-03	-5.98	actin filament binding	molecular function	GO:0051015	211	4	18094	49	NEBL,ABLIM1,CTNNA2,MACF1
2.545e-03	-5.97	lung-carcinoma-large_cell_carcinoma	COSMIC cancer mutations	lung-carcinoma-large_cell_carcinoma	849	8	16828	48	NTRK2,DPP10,PTPRZ1,BMPR1B,TNIK,RPS6KA2,MAP3K5,DCLK2
2.545e-03	-5.97	large_cell_carcinoma	COSMIC cancer mutations	large_cell_carcinoma	849	8	16828	48	MAP3K5,DCLK2,DPP10,NTRK2,BMPR1B,PTPRZ1,TNIK,RPS6KA2
2.570e-03	-5.96	Dynlt1 (dynein light chain Tctex-type 1)	protein interactions	83462	1	1	19454	50	NTRK2
2.570e-03	-5.96	Agtrap (angiotensin II, type I receptor-associated protein)	protein interactions	11610	1	1	19454	50	PITPNC1
2.570e-03	-5.96	Lztr1 (leucine-zipper-like transcriptional regulator, 1)	protein interactions	66863	1	1	19454	50	BMPR1B
2.570e-03	-5.96	Bdnf (brain derived neurotrophic factor)	protein interactions	12064	1	1	19454	50	NTRK2
2.570e-03	-5.96	Hipk3 (homeodomain interacting protein kinase 3)	protein interactions	15259	1	1	19454	50	GLIS3
2.570e-03	-5.96	Isl1 (ISL1 transcription factor, LIM/homeodomain)	protein interactions	16392	1	1	19454	50	GLIS3
2.570e-03	-5.96	Dcaf7 (DDB1 and CUL4 associated factor 7)	protein interactions	71833	1	1	19454	50	BMPR1B
2.570e-03	-5.96	1700006A11Rik (RIKEN cDNA 1700006A11 gene)	protein interactions	71824	1	1	19454	50	BMPR1B
2.585e-03	-5.96	Pkinase	pfam domains	PF00069	347	5	17795	49	RPS6KA2,TNIK,MAP3K5,MAPK10,DCLK2
2.593e-03	-5.95	Calcium-transporting ATPase, transmembrane domain	gene3d domains	1.20.1110.10	25	2	14470	44	ATP1A2,ATP13A4
2.617e-03	-5.95	perinuclear endoplasmic reticulum lumen	cellular component	GO:0099020	1	1	19108	50	CLU
2.690e-03	-5.92	Cellular Senescence	REACTOME pathways	R-HSA-2559583	196	4	10285	31	RPS6KA2,MAP3K5,TNIK,MAPK10
2.692e-03	-5.92	trans-synaptic signaling by neuropeptide	biological process	GO:0099540	1	1	18204	49	NTRK2
2.692e-03	-5.92	regulation of neuronal signal transduction	biological process	GO:1902847	1	1	18204	49	CLU
2.692e-03	-5.92	homologous chromosome movement towards spindle pole in meiosis I anaphase	biological process	GO:0051758	1	1	18204	49	FMN2
2.692e-03	-5.92	negative regulation of calcium:sodium antiporter activity	biological process	GO:1903280	1	1	18204	49	ATP1A2
2.692e-03	-5.92	trans-synaptic signaling by neuropeptide, modulating synaptic transmission	biological process	GO:0099551	1	1	18204	49	NTRK2
2.692e-03	-5.92	chemorepulsion involved in interneuron migration from the subpallium to the cortex	biological process	GO:0021842	1	1	18204	49	NRG3
2.692e-03	-5.92	olfactory cortex development	biological process	GO:0021989	1	1	18204	49	ATP1A2
2.692e-03	-5.92	positive regulation of neurofibrillary tangle assembly	biological process	GO:1902998	1	1	18204	49	CLU
2.692e-03	-5.92	directional guidance of interneurons involved in migration from the subpallium to the cortex	biological process	GO:0021840	1	1	18204	49	NRG3
2.700e-03	-5.91	RSK3_STKc	interpro domains	IPR042766	1	1	18521	50	RPS6KA2
2.700e-03	-5.91	SORBS1_SH3_1	interpro domains	IPR035610	1	1	18521	50	SORBS1
2.700e-03	-5.91	NTRK2	interpro domains	IPR020455	1	1	18521	50	NTRK2
2.700e-03	-5.91	TRPS1	interpro domains	IPR028440	1	1	18521	50	TRPS1
2.700e-03	-5.91	Nebulette_SH3	interpro domains	IPR035631	1	1	18521	50	NEBL
2.700e-03	-5.91	M14_CPE_CPD	interpro domains	IPR034232	1	1	18521	50	CPE
2.700e-03	-5.91	Clusterin	interpro domains	IPR016016	1	1	18521	50	CLU
2.700e-03	-5.91	RBMS3_RRM2	interpro domains	IPR034406	1	1	18521	50	RBMS3
2.700e-03	-5.91	SORBS1_SH3_2	interpro domains	IPR035611	1	1	18521	50	SORBS1
2.700e-03	-5.91	SORBS1_SH3	interpro domains	IPR035606	1	1	18521	50	SORBS1
2.700e-03	-5.91	Clusterin_CS	interpro domains	IPR033986	1	1	18521	50	CLU
2.708e-03	-5.91	peptidoglycan glycosyltransferase activity	molecular function	GO:0008955	1	1	18094	49	CSGALNACT1
2.708e-03	-5.91	brain-derived neurotrophic factor receptor activity	molecular function	GO:0060175	1	1	18094	49	NTRK2
2.724e-03	-5.91	transferase activity, transferring phosphorus-containing groups	molecular function	GO:0016772	903	8	18094	49	NTRK2,MAPK10,DCLK2,RPS6KA2,MAP3K5,EFEMP1,TNIK,BMPR1B
2.747e-03	-5.90	positive regulation of biological process	biological process	GO:0048518	6326	27	18204	49	DPP10,NPAS3,CLU,SORBS1,FMN2,ATP1A2,SOX5,SLC4A4,TNIK,GLIS3,MACF1,RFX4,PTPRZ1,GPC5,MAP3K5,NRCAM,SPON1,NTRK2,HPSE2,GPM6A,SLC1A2,RBMS3,RORA,BMPR1B,PARD3,RPS6KA2,NAV3
2.751e-03	-5.90	myelination in peripheral nervous system	biological process	GO:0022011	29	2	18204	49	NTRK2,PARD3
2.751e-03	-5.90	peripheral nervous system axon ensheathment	biological process	GO:0032292	29	2	18204	49	PARD3,NTRK2
2.827e-03	-5.87	glial cell differentiation	biological process	GO:0010001	219	4	18204	49	PARD3,CLU,PTPRZ1,NTRK2
2.830e-03	-5.87	Proximal tubule bicarbonate reclamation	KEGG pathways	ko04964	23	2	7161	25	ATP1A2,SLC4A4
2.830e-03	-5.87	Proximal tubule bicarbonate reclamation	KEGG pathways	hsa04964	23	2	7161	25	SLC4A4,ATP1A2
2.853e-03	-5.86	cell communication	biological process	GO:0007154	5010	23	18204	49	BMPR1B,RORA,SLC1A2,NTRK2,NRCAM,MAP3K5,PITPNC1,EFEMP1,MAPK10,CPE,RPS6KA2,PARD3,ADCY2,SORBS1,CLU,DTNA,MACF1,TNIK,CTNND2,DCLK2,NRG3,ATP1A2,FMN2
2.863e-03	-5.86	DST (dystonin)	protein interactions	667	230	4	19454	50	TNIK,PARD3,NTRK2,ATP1A2
2.888e-03	-5.85	protein serine kinase activity	molecular function	GO:0106310	362	5	18094	49	MAP3K5,MAPK10,RPS6KA2,DCLK2,TNIK
2.897e-03	-5.84	germ_cell_tumour	COSMIC cancer mutations	germ_cell_tumour	867	8	16828	48	MAP3K5,DCLK2,MACF1,NTRK2,BMPR1B,TRPS1,TNIK,RPS6KA2
2.901e-03	-5.84	lung-carcinoid-endocrine_tumour	COSMIC cancer mutations	lung-carcinoid-endocrine_tumour	502	6	16828	48	TNIK,DCLK2,RPS6KA2,NTRK2,BMPR1B,MAP3K5
2.916e-03	-5.84	cell junction organization	biological process	GO:0034330	532	6	18204	49	CTNND2,NRCAM,PARD3,NRG3,SORBS1,GPM6A
2.942e-03	-5.83	neurotransmitter uptake	biological process	GO:0001504	30	2	18204	49	SLC1A2,ATP1A2
2.950e-03	-5.83	axonogenesis	biological process	GO:0007409	366	5	18204	49	PTPRZ1,BMPR1B,PARD3,NRCAM,CTNNA2
2.978e-03	-5.82	poly-pyrimidine tract binding	molecular function	GO:0008187	30	2	18094	49	RBMS3,MSI2
3.040e-03	-5.80	beta-catenin binding	molecular function	GO:0008013	107	3	18094	49	RORA,CTNND2,CTNNA2
3.055e-03	-5.79	CDH1 (cadherin 1)	protein interactions	999	757	7	19454	50	NEBL,PARD3,CTNND2,CTNNA2,MACF1,SORBS1,ABLIM1
3.076e-03	-5.78	lung-carcinoid-endocrine_tumour-atypical	COSMIC cancer mutations	lung-carcinoid-endocrine_tumour-atypical	508	6	16828	48	DCLK2,TNIK,RPS6KA2,NTRK2,BMPR1B,MAP3K5
3.093e-03	-5.78	MARK3 (microtubule affinity regulating kinase 3)	protein interactions	4140	235	4	19454	50	NTRK2,DTNA,MACF1,PARD3
3.195e-03	-5.75	ion binding	molecular function	GO:0043167	6007	26	18094	49	EFEMP1,DCLK2,NAV3,PARD3,SLC1A2,PITPNC1,TNIK,ATP1A2,MAP3K5,RPS6KA2,ATP13A4,ADCY2,PAMR1,GLIS3,TRPS1,NTRK2,BMPR1B,CSGALNACT1,MACF1,DTNA,MGAT4C,RORA,SPON1,CPE,MAPK10,ABLIM1
3.222e-03	-5.74	SMAD7 (SMAD family member 7)	protein interactions	4092	115	3	19454	50	PARD3,SOX5,BMPR1B
3.224e-03	-5.74	human chr11p13	chromosome location	human chr11p13	44	2	26134	50	PAMR1,SLC1A2
3.237e-03	-5.73	LCOR (ligand dependent nuclear receptor corepressor)	protein interactions	84458	238	4	19454	50	NAV3,CLU,NRCAM,MACF1
3.249e-03	-5.73	NTM (neurotrimin)	protein interactions	50863	33	2	19454	50	GPM6A,LSAMP
3.253e-03	-5.73	extracellular matrix	cellular component	GO:0031012	559	6	19108	50	GPC5,EFEMP1,SPON1,HPSE2,CLU,PTPRZ1
3.253e-03	-5.73	adrenal_cortical_carcinoma	COSMIC cancer mutations	adrenal_cortical_carcinoma	2256	14	16828	48	HPSE2,NRG3,RFX4,FMN2,PTPRZ1,ATP1A2,SOX5,MAP3K5,CTNND2,SLC1A2,TRPM3,NRCAM,NTRK2,EFEMP1
3.282e-03	-5.72	external encapsulating structure	cellular component	GO:0030312	560	6	19108	50	EFEMP1,GPC5,HPSE2,SPON1,PTPRZ1,CLU
3.282e-03	-5.72	E1-E2_ATPase	pfam domains	PF00122	31	2	17795	49	ATP1A2,ATP13A4
3.291e-03	-5.72	atypical	COSMIC cancer mutations	atypical	515	6	16828	48	TNIK,RPS6KA2,NTRK2,BMPR1B,DCLK2,MAP3K5
3.330e-03	-5.70	central_nervous_system-cerebellum-glioma-astrocytoma_Grade_I	COSMIC cancer mutations	central_nervous_system-cerebellum-glioma-astrocytoma_Grade_I	105	3	16828	48	NRG3,GPC5,PARD3
3.344e-03	-5.70	positive regulation of cartilage development	biological process	GO:0061036	32	2	18204	49	BMPR1B,SOX5
3.394e-03	-5.69	Transmembrane transport of small molecules	REACTOME pathways	R-HSA-382551	677	7	10285	31	AQP4,ADCY2,ATP1A2,SLC1A2,ATP13A4,SLC4A4,TRPM3
3.442e-03	-5.67	adenyl nucleotide binding	molecular function	GO:0030554	1620	11	18094	49	NAV3,DCLK2,ADCY2,MAPK10,NTRK2,BMPR1B,ATP1A2,TNIK,MAP3K5,RPS6KA2,ATP13A4
3.447e-03	-5.67	CLUSTERIN_1	prosite domains	PS00492	1	1	12186	42	CLU
3.447e-03	-5.67	CLUSTERIN_2	prosite domains	PS00493	1	1	12186	42	CLU
3.485e-03	-5.66	seminoma	COSMIC cancer mutations	seminoma	700	7	16828	48	DCLK2,MAP3K5,RPS6KA2,TRPS1,TNIK,BMPR1B,NTRK2
3.495e-03	-5.66	Cation_ATPase	pfam domains	PF13246	32	2	17795	49	ATP1A2,ATP13A4
3.705e-03	-5.60	DELLA	smart domains	SM01129	1	1	9717	36	MACF1
3.749e-03	-5.59	membrane	cellular component	GO:0016020	9220	34	19108	50	ATP13A4,NRG3,NTRK2,CPE,HIF3A,MAPK10,NRCAM,NKAIN3,FMN2,CTNNA2,MGAT4C,DPP10,SORBS1,BMPR1B,LSAMP,PARD3,AQP4,ATP1A2,MAP3K5,GPC5,SLC4A4,CSGALNACT1,MACF1,TNIK,HPSE2,ADCY2,GPM6A,SLC1A2,DTNA,CLU,NAV3,TRPM3,CTNND2,PTPRZ1
3.792e-03	-5.57	PAS	interpro domains	IPR000014	34	2	18521	50	HIF3A,NPAS3
3.792e-03	-5.57	PAS-like_dom_sf	interpro domains	IPR035965	34	2	18521	50	HIF3A,NPAS3
3.795e-03	-5.57	PAS	smart domains	SM00091	25	2	9717	36	HIF3A,NPAS3
3.822e-03	-5.57	regulation of cellular process	biological process	GO:0050794	11468	40	18204	49	CPE,PITPNC1,MAPK10,EFEMP1,PARD3,NAV3,RPS6KA2,RORA,RBMS3,BMPR1B,SPON1,NRCAM,MAP3K5,GPM6A,SLC1A2,HPSE2,NTRK2,RFX4,MACF1,TRPS1,GLIS3,CTNND2,TNIK,GPC5,PTPRZ1,ATP1A2,NRG3,FMN2,SLC4A4,DCLK2,SOX5,CLU,DTNA,ADCY2,SORBS1,DPP10,CTNNA2,MSI2,NPAS3,HIF3A
3.826e-03	-5.57	NTKRECEPTOR2	prints domains	PR01941	1	1	5227	20	NTRK2
3.826e-03	-5.57	AQUAPORIN4	prints domains	PR02016	1	1	5227	20	AQP4
3.846e-03	-5.56	Progesterone-mediated oocyte maturation	KEGG pathways	ko04914	92	3	7161	25	ADCY2,RPS6KA2,MAPK10
3.846e-03	-5.56	Progesterone-mediated oocyte maturation	KEGG pathways	hsa04914	92	3	7161	25	MAPK10,ADCY2,RPS6KA2
3.866e-03	-5.56	cell adhesion molecule binding	molecular function	GO:0050839	560	6	18094	49	NRCAM,CPE,CTNND2,MACF1,CTNNA2,PTPRZ1
3.872e-03	-5.55	MAPK targets/ Nuclear events mediated by MAP kinases	REACTOME pathways	R-HSA-450282	31	2	10285	31	RPS6KA2,MAPK10
3.937e-03	-5.54	synapse assembly	biological process	GO:0007416	118	3	18204	49	NRCAM,NRG3,GPM6A
3.947e-03	-5.53	TRAF2 (TNF receptor associated factor 2)	protein interactions	7186	592	6	19454	50	TNIK,NEBL,MAP3K5,EFEMP1,ABLIM1,SOX5
4.052e-03	-5.51	cervix-carcinoma-squamous_cell_carcinoma	COSMIC cancer mutations	cervix-carcinoma-squamous_cell_carcinoma	11789	42	16828	48	HIF3A,DTNA,MAP3K5,ABLIM1,GPC5,TRPS1,NAV3,RPS6KA2,SLC1A2,NTRK2,PARD3,NRCAM,TRPM3,NRG3,DCLK2,LSAMP,SORBS1,PAMR1,GLIS3,RORA,SLC4A4,PTPRZ1,NEBL,BMPR1B,ATP1A2,MACF1,SPON1,GPM6A,SOX5,ADCY2,CPE,ATP13A4,CTNND2,DPP10,HPSE2,CSGALNACT1,MGAT4C,RFX4,FMN2,TNIK,NPAS3,PITPNC1
4.093e-03	-5.50	cervix	COSMIC cancer mutations	cervix	11793	42	16828	48	GPM6A,CPE,ATP13A4,SOX5,ADCY2,SPON1,MACF1,ATP1A2,DPP10,CTNND2,RFX4,FMN2,MGAT4C,CSGALNACT1,HPSE2,PITPNC1,NPAS3,TNIK,MAP3K5,DTNA,HIF3A,PARD3,TRPM3,NRCAM,NTRK2,NAV3,RPS6KA2,SLC1A2,ABLIM1,TRPS1,GPC5,RORA,GLIS3,PAMR1,LSAMP,SORBS1,NRG3,DCLK2,PTPRZ1,BMPR1B,NEBL,SLC4A4
4.210e-03	-5.47	Pancreatic secretion	KEGG pathways	hsa04972	95	3	7161	25	ATP1A2,ADCY2,SLC4A4
4.210e-03	-5.47	Pancreatic secretion	KEGG pathways	ko04972	95	3	7161	25	ATP1A2,ADCY2,SLC4A4
4.215e-03	-5.47	glial cell projection	cellular component	GO:0097386	37	2	19108	50	SLC1A2,AQP4
4.244e-03	-5.46	P_typ_ATPase	interpro domains	IPR001757	36	2	18521	50	ATP1A2,ATP13A4
4.244e-03	-5.46	ATPase_P-typ_cyto_dom_N	interpro domains	IPR023299	36	2	18521	50	ATP13A4,ATP1A2
4.244e-03	-5.46	ATPase_P-typ_transduc_dom_A_sf	interpro domains	IPR008250	36	2	18521	50	ATP1A2,ATP13A4
4.244e-03	-5.46	ATPase_P-typ_P_site	interpro domains	IPR018303	36	2	18521	50	ATP1A2,ATP13A4
4.244e-03	-5.46	P_typ_ATPase_HD_dom	interpro domains	IPR044492	36	2	18521	50	ATP13A4,ATP1A2
4.281e-03	-5.45	regulation of synapse organization	biological process	GO:0050807	246	4	18204	49	CTNNA2,NRCAM,GPM6A,NTRK2
4.344e-03	-5.44	glutamatergic synapse	cellular component	GO:0098978	412	5	19108	50	GPM6A,NRCAM,TNIK,NRG3,SLC1A2
4.432e-03	-5.42	chondroitin biosynthesis	BIOCYC pathways	HUMAN_PWY-6566	2	1	902	2	CSGALNACT1
4.451e-03	-5.41	positive regulation of glucose import	biological process	GO:0046326	37	2	18204	49	SLC1A2,SORBS1
4.478e-03	-5.41	ATPase_P-typ_TM_dom_sf	interpro domains	IPR023298	37	2	18521	50	ATP1A2,ATP13A4
4.481e-03	-5.41	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-acute_lymphoblastic_leukaemia	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-acute_lymphoblastic_leukaemia	2081	13	16828	48	PTPRZ1,BMPR1B,SLC4A4,TNIK,DCLK2,NTRK2,RPS6KA2,TRPS1,ADCY2,SOX5,MAP3K5,DTNA,ATP1A2
4.494e-03	-5.41	DIRAS3 (DIRAS family GTPase 3)	protein interactions	9077	261	4	19454	50	FMN2,PARD3,MACF1,DTNA
4.506e-03	-5.40	cellular component assembly	biological process	GO:0022607	2472	14	18204	49	AQP4,ABLIM1,RFX4,TNIK,TRPM3,NRG3,PARD3,FMN2,SORBS1,CLU,NEBL,GPM6A,SLC1A2,NRCAM
4.523e-03	-5.40	action potential	biological process	GO:0001508	124	3	18204	49	NTRK2,ATP1A2,NRCAM
4.530e-03	-5.40	ovary-carcinoma	COSMIC cancer mutations	ovary-carcinoma	933	8	16828	48	NTRK2,BMPR1B,TNIK,RPS6KA2,MAP3K5,ATP1A2,DCLK2,MACF1
4.602e-03	-5.38	FGFR1 (fibroblast growth factor receptor 1)	protein interactions	2260	611	6	19454	50	DTNA,RPS6KA2,PARD3,TNIK,CLU,ABLIM1
4.662e-03	-5.37	regulation of synapse structure or activity	biological process	GO:0050803	252	4	18204	49	GPM6A,NTRK2,CTNNA2,NRCAM
4.744e-03	-5.35	DZIP1 (DAZ interacting zinc finger protein 1)	protein interactions	22873	40	2	19454	50	PARD3,NTRK2
4.745e-03	-5.35	PAS	prosite domains	PS50112	30	2	12186	42	HIF3A,NPAS3
4.783e-03	-5.34	lung-left_upper_lobe-carcinoma-adenocarcinoma	COSMIC cancer mutations	lung-left_upper_lobe-carcinoma-adenocarcinoma	556	6	16828	48	CTNND2,NAV3,TRPS1,NTRK2,SLC4A4,ADCY2
4.867e-03	-5.33	left_upper_lobe	COSMIC cancer mutations	left_upper_lobe	558	6	16828	48	TRPS1,NAV3,CTNND2,NTRK2,SLC4A4,ADCY2
4.942e-03	-5.31	myelination	biological process	GO:0042552	128	3	18204	49	NTRK2,CLU,PARD3
4.942e-03	-5.31	glial cell development	biological process	GO:0021782	128	3	18204	49	NTRK2,CLU,PARD3
4.980e-03	-5.30	RASSF7 (Ras association domain family member 7)	protein interactions	8045	41	2	19454	50	PARD3,CLU
5.080e-03	-5.28	stomach-carcinoma-mixed_intestinal_and_diffuse_adenocarcinoma-unclassifiable	COSMIC cancer mutations	stomach-carcinoma-mixed_intestinal_and_diffuse_adenocarcinoma-unclassifiable	951	8	16828	48	SLC1A2,GPC5,PARD3,TRPM3,DPP10,MACF1,FMN2,ATP13A4
5.080e-03	-5.28	mixed_intestinal_and_diffuse_adenocarcinoma-unclassifiable	COSMIC cancer mutations	mixed_intestinal_and_diffuse_adenocarcinoma-unclassifiable	951	8	16828	48	FMN2,ATP13A4,MACF1,PARD3,TRPM3,DPP10,SLC1A2,GPC5
5.099e-03	-5.28	collagen-containing extracellular matrix	cellular component	GO:0062023	428	5	19108	50	SPON1,EFEMP1,GPC5,CLU,PTPRZ1
5.134e-03	-5.27	Zmym2 (zinc finger, MYM-type 2)	protein interactions	76007	2	1	19454	50	GLIS3
5.134e-03	-5.27	Kdm4c (lysine (K)-specific demethylase 4C)	protein interactions	76804	2	1	19454	50	GLIS3
5.134e-03	-5.27	Irf7 (interferon regulatory factor 7)	protein interactions	54123	2	1	19454	50	BMPR1B
5.134e-03	-5.27	Mknk2 (MAP kinase-interacting serine/threonine kinase 2)	protein interactions	17347	2	1	19454	50	BMPR1B
5.134e-03	-5.27	Sh3kbp1 (SH3-domain kinase binding protein 1)	protein interactions	58194	2	1	19454	50	BMPR1B
5.134e-03	-5.27	Bcr (BCR activator of RhoGEF and GTPase)	protein interactions	110279	2	1	19454	50	BMPR1B
5.134e-03	-5.27	Fkbp1a (FK506 binding protein 1a)	protein interactions	14225	2	1	19454	50	BMPR1B
5.134e-03	-5.27	Klhl1 (kelch-like 1)	protein interactions	93688	2	1	19454	50	BMPR1B
5.134e-03	-5.27	Ppp3cc (protein phosphatase 3, catalytic subunit, gamma isoform)	protein interactions	19057	2	1	19454	50	BMPR1B
5.134e-03	-5.27	Bmpr2 (bone morphogenetic protein receptor type 2)	protein interactions	12168	2	1	19454	50	BMPR1B
5.134e-03	-5.27	Fbxo34 (F-box protein 34)	protein interactions	78938	2	1	19454	50	BMPR1B
5.134e-03	-5.27	Fkbp1b (FK506 binding protein 1b)	protein interactions	14226	2	1	19454	50	BMPR1B
5.148e-03	-5.27	small molecule binding	molecular function	GO:0036094	6197	26	18094	49	GLIS3,PAMR1,TRPS1,ADCY2,NTRK2,PITPNC1,TNIK,ATP1A2,MAP3K5,ATP13A4,RPS6KA2,NAV3,DCLK2,SLC1A2,PARD3,EFEMP1,SPON1,MAPK10,ABLIM1,CPE,MGAT4C,RORA,BMPR1B,CSGALNACT1,MACF1,DTNA
5.160e-03	-5.27	axon ensheathment	biological process	GO:0008366	130	3	18204	49	NTRK2,CLU,PARD3
5.160e-03	-5.27	ensheathment of neurons	biological process	GO:0007272	130	3	18204	49	CLU,PARD3,NTRK2
5.187e-03	-5.26	cyclic purine nucleotide metabolic process	biological process	GO:0052652	40	2	18204	49	RORA,ADCY2
5.198e-03	-5.26	RDX (radixin)	protein interactions	5962	272	4	19454	50	MAPK10,MACF1,NEBL,ABLIM1
5.260e-03	-5.25	biological regulation	biological process	GO:0065007	12501	42	18204	49	SORBS1,ADCY2,DTNA,CLU,HIF3A,NPAS3,MSI2,CTNNA2,DPP10,PTPRZ1,GPC5,AQP4,TNIK,CTNND2,GLIS3,RFX4,MACF1,TRPS1,SOX5,SLC4A4,DCLK2,FMN2,NRG3,ATP1A2,BMPR1B,RBMS3,RORA,NTRK2,HPSE2,SLC1A2,GPM6A,NRCAM,MAP3K5,SPON1,MAPK10,EFEMP1,PITPNC1,CPE,RPS6KA2,NKAIN3,NAV3,PARD3
5.265e-03	-5.25	FLOT2 (flotillin 2)	protein interactions	2319	273	4	19454	50	RPS6KA2,NTRK2,PARD3,SOX5
5.288e-03	-5.24	axon development	biological process	GO:0061564	420	5	18204	49	BMPR1B,PTPRZ1,NRCAM,CTNNA2,PARD3
5.331e-03	-5.23	Calcium-transporting ATPase, cytoplasmic transduction domain A	gene3d domains	2.70.150.10	36	2	14470	44	ATP13A4,ATP1A2
5.331e-03	-5.23	Calcium-transporting ATPase, cytoplasmic domain N	gene3d domains	3.40.1110.10	36	2	14470	44	ATP13A4,ATP1A2
5.376e-03	-5.23	chondroitin sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process	biological process	GO:0050653	2	1	18204	49	CSGALNACT1
5.376e-03	-5.23	UDP-glucuronate metabolic process	biological process	GO:0046398	2	1	18204	49	CSGALNACT1
5.376e-03	-5.23	regulation of neurofibrillary tangle assembly	biological process	GO:1902996	2	1	18204	49	CLU
5.376e-03	-5.23	neuron intrinsic apoptotic signaling pathway in response to oxidative stress	biological process	GO:0036480	2	1	18204	49	MAP3K5
5.392e-03	-5.22	Alpha_CARP_receptor-type	interpro domains	IPR041887	2	1	18521	50	PTPRZ1
5.392e-03	-5.22	Distrobrevin	interpro domains	IPR017432	2	1	18521	50	DTNA
5.392e-03	-5.22	Spondin_N_sf	interpro domains	IPR038678	2	1	18521	50	SPON1
5.392e-03	-5.22	Clusterin-like	interpro domains	IPR000753	2	1	18521	50	CLU
5.392e-03	-5.22	Clusterin_C	interpro domains	IPR016015	2	1	18521	50	CLU
5.392e-03	-5.22	MSI_RRM2	interpro domains	IPR034126	2	1	18521	50	MSI2
5.392e-03	-5.22	Spondin_N	interpro domains	IPR009465	2	1	18521	50	SPON1
5.392e-03	-5.22	Clusterin_N	interpro domains	IPR016014	2	1	18521	50	CLU
5.392e-03	-5.22	Formin_Cappuccino_subfam	interpro domains	IPR001265	2	1	18521	50	FMN2
5.392e-03	-5.22	Glyco_hydro_79	interpro domains	IPR005199	2	1	18521	50	HPSE2
5.392e-03	-5.22	Par3/HAL_N	interpro domains	IPR021922	2	1	18521	50	PARD3
5.409e-03	-5.22	heparanase activity	molecular function	GO:0030305	2	1	18094	49	HPSE2
5.432e-03	-5.22	Ig_I-set	interpro domains	IPR013098	132	3	18521	50	NRCAM,LSAMP,NTRK2
5.443e-03	-5.21	cyclic nucleotide metabolic process	biological process	GO:0009187	41	2	18204	49	ADCY2,RORA
5.467e-03	-5.21	central_nervous_system-brain-glioma-oligodendroglioma_Grade_III	COSMIC cancer mutations	central_nervous_system-brain-glioma-oligodendroglioma_Grade_III	249	4	16828	48	MGAT4C,GLIS3,PTPRZ1,MACF1
5.500e-03	-5.20	Par3_HAL_N_term	pfam domains	PF12053	2	1	17795	49	PARD3
5.500e-03	-5.20	Clusterin	pfam domains	PF01093	2	1	17795	49	CLU
5.500e-03	-5.20	Glyco_hydro_79n	pfam domains	PF03662	2	1	17795	49	HPSE2
5.500e-03	-5.20	Reeler	pfam domains	PF02014	2	1	17795	49	SPON1
5.500e-03	-5.20	Spond_N	pfam domains	PF06468	2	1	17795	49	SPON1
5.544e-03	-5.20	small_intestine	COSMIC cancer mutations	small_intestine	250	4	16828	48	TNIK,MACF1,MGAT4C,CSGALNACT1
5.609e-03	-5.18	regulation of biological process	biological process	GO:0050789	12079	41	18204	49	RORA,RBMS3,BMPR1B,SPON1,MAP3K5,NRCAM,SLC1A2,GPM6A,HPSE2,NTRK2,CPE,PITPNC1,EFEMP1,MAPK10,PARD3,NKAIN3,NAV3,RPS6KA2,CLU,DTNA,ADCY2,SORBS1,DPP10,CTNNA2,MSI2,NPAS3,HIF3A,RFX4,TRPS1,MACF1,GLIS3,CTNND2,TNIK,PTPRZ1,GPC5,ATP1A2,NRG3,FMN2,DCLK2,SLC4A4,SOX5
5.611e-03	-5.18	cytoskeleton organization	biological process	GO:0007010	1251	9	18204	49	DCLK2,PARD3,CTNNA2,FMN2,SORBS1,ABLIM1,MACF1,TNIK,NEBL
5.706e-03	-5.17	Schwann cell development	biological process	GO:0014044	42	2	18204	49	PARD3,NTRK2
5.731e-03	-5.16	I-set	pfam domains	PF07679	132	3	17795	49	LSAMP,NRCAM,NTRK2
5.885e-03	-5.14	haematopoietic_neoplasm	COSMIC cancer mutations	haematopoietic_neoplasm	11082	40	16828	48	GPC5,ABLIM1,RPS6KA2,NAV3,NKAIN3,SLC1A2,NTRK2,EFEMP1,PARD3,TRPM3,HIF3A,MSI2,DTNA,MAP3K5,SLC4A4,PTPRZ1,BMPR1B,NEBL,NRG3,DCLK2,LSAMP,PAMR1,GLIS3,RORA,CTNND2,DPP10,ATP1A2,MACF1,SPON1,CPE,SOX5,ADCY2,ATP13A4,TNIK,NPAS3,HPSE2,RBMS3,CSGALNACT1,FMN2,RFX4
5.908e-03	-5.13	signal transduction	biological process	GO:0007165	4637	21	18204	49	DCLK2,RPS6KA2,NRG3,ATP1A2,PARD3,FMN2,PITPNC1,EFEMP1,MAPK10,CPE,MACF1,TNIK,CTNND2,NTRK2,MAP3K5,ADCY2,SORBS1,BMPR1B,RORA,CLU,DTNA
5.922e-03	-5.13	SLC6A15 (solute carrier family 6 member 15)	protein interactions	55117	143	3	19454	50	PARD3,RPS6KA2,NTRK2
5.941e-03	-5.13	rhythmic process	biological process	GO:0048511	270	4	18204	49	BMPR1B,NTRK2,MAPK10,RORA
5.946e-03	-5.12	spleen	COSMIC cancer mutations	spleen	408	5	16828	48	ADCY2,MAP3K5,PTPRZ1,SORBS1,TNIK
6.001e-03	-5.12	YWHAH (tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein eta)	protein interactions	7533	1083	8	19454	50	ABLIM1,SORBS1,MACF1,FMN2,DCLK2,PARD3,MAP3K5,PITPNC1
6.010e-03	-5.11	Glycosaminoglycan metabolism	REACTOME pathways	R-HSA-1630316	124	3	10285	31	HPSE2,CSGALNACT1,GPC5
6.020e-03	-5.11	somatodendritic compartment	cellular component	GO:0036477	842	7	19108	50	BMPR1B,GPM6A,CLU,ADCY2,NTRK2,ATP1A2,CTNND2
6.044e-03	-5.11	protein serine/threonine/tyrosine kinase activity	molecular function	GO:0004712	43	2	18094	49	MAPK10,RPS6KA2
6.066e-03	-5.11	signaling	biological process	GO:0023052	4968	22	18204	49	MAPK10,EFEMP1,PITPNC1,TNIK,CTNND2,MACF1,CPE,RPS6KA2,DCLK2,FMN2,NRG3,ATP1A2,PARD3,SORBS1,BMPR1B,ADCY2,DTNA,CLU,RORA,NTRK2,SLC1A2,MAP3K5
6.073e-03	-5.10	Vinculin, Vh2 four-helix bundle	gene3d domains	1.20.120.810	2	1	14470	44	CTNNA2
6.073e-03	-5.10	F-spondin domain	gene3d domains	2.60.40.2130	2	1	14470	44	SPON1
6.102e-03	-5.10	sarcolemma	cellular component	GO:0042383	142	3	19108	50	DTNA,AQP4,ATP1A2
6.108e-03	-5.10	LCK (LCK proto-oncogene, Src family tyrosine kinase)	protein interactions	3932	455	5	19454	50	FMN2,CTNND2,MACF1,DTNA,PARD3
6.190e-03	-5.08	skin-leg-malignant_melanoma-nodular	COSMIC cancer mutations	skin-leg-malignant_melanoma-nodular	258	4	16828	48	PTPRZ1,FMN2,ATP13A4,SLC4A4
6.234e-03	-5.08	EXTL2 (exostosin like glycosyltransferase 2)	protein interactions	2135	46	2	19454	50	CLU,MGAT4C
6.247e-03	-5.08	positive regulation of glucose transmembrane transport	biological process	GO:0010828	44	2	18204	49	SORBS1,SLC1A2
6.272e-03	-5.07	PARD3 (par-3 family cell polarity regulator)	protein interactions	56288	287	4	19454	50	NTRK2,DTNA,SORBS1,PARD3
6.272e-03	-5.07	DSCR9 (Down syndrome critical region 9)	protein interactions	257203	146	3	19454	50	CLU,MACF1,EFEMP1
6.283e-03	-5.07	Oxidative Stress Induced Senescence	REACTOME pathways	R-HSA-2559580	126	3	10285	31	MAPK10,MAP3K5,TNIK
6.334e-03	-5.06	gliogenesis	biological process	GO:0042063	275	4	18204	49	PARD3,CLU,NTRK2,PTPRZ1
6.348e-03	-5.06	VASP (vasodilator stimulated phosphoprotein)	protein interactions	7408	288	4	19454	50	NEBL,SORBS1,PARD3,FMN2
6.387e-03	-5.05	active monoatomic ion transmembrane transporter activity	molecular function	GO:0022853	274	4	18094	49	ATP1A2,SLC4A4,ATP13A4,SLC1A2
6.467e-03	-5.04	ovary-carcinoma-serous_carcinoma	COSMIC cancer mutations	ovary-carcinoma-serous_carcinoma	10710	39	16828	48	CLU,CTNND2,DPP10,ATP1A2,MACF1,SOX5,CPE,ADCY2,ATP13A4,TNIK,NPAS3,HPSE2,CSGALNACT1,MGAT4C,FMN2,TRPS1,GPC5,NAV3,RPS6KA2,SLC1A2,NTRK2,EFEMP1,PARD3,TRPM3,NRCAM,MSI2,DTNA,MAP3K5,SLC4A4,PTPRZ1,NEBL,BMPR1B,NRG3,DCLK2,SORBS1,LSAMP,PAMR1,RORA,GLIS3
6.500e-03	-5.04	BDNF (brain derived neurotrophic factor)	protein interactions	627	47	2	19454	50	CPE,NTRK2
6.500e-03	-5.04	CNTN1 (contactin 1)	protein interactions	1272	47	2	19454	50	GPM6A,PTPRZ1
6.527e-03	-5.03	acidic amino acid transport	biological process	GO:0015800	45	2	18204	49	SLC1A2,NTRK2
6.550e-03	-5.03	postsynapse	cellular component	GO:0098794	646	6	19108	50	CTNND2,ATP1A2,NTRK2,TNIK,GPM6A,NRCAM
6.550e-03	-5.03	PAS domain	gene3d domains	3.30.450.20	40	2	14470	44	HIF3A,NPAS3
6.588e-03	-5.02	neuron migration	biological process	GO:0001764	142	3	18204	49	NTRK2,GPM6A,NRCAM
6.601e-03	-5.02	regulation of neuron projection development	biological process	GO:0010975	443	5	18204	49	NTRK2,MACF1,NRCAM,CTNNA2,TNIK
6.642e-03	-5.01	endometrium-carcinoma-serous_carcinoma	COSMIC cancer mutations	endometrium-carcinoma-serous_carcinoma	1442	10	16828	48	SORBS1,LSAMP,FMN2,CTNND2,TNIK,GPC5,TRPS1,PARD3,TRPM3,SLC4A4
6.702e-03	-5.01	kidney-carcinoma-clear_cell_renal_cell_carcinoma	COSMIC cancer mutations	kidney-carcinoma-clear_cell_renal_cell_carcinoma	13924	46	16828	48	DPP10,CLU,CTNND2,GPM6A,SOX5,ADCY2,ATP13A4,CPE,SPON1,MACF1,ATP1A2,PITPNC1,NPAS3,TNIK,FMN2,MGAT4C,CSGALNACT1,HPSE2,PARD3,TRPM3,NRCAM,NTRK2,EFEMP1,NKAIN3,NAV3,RPS6KA2,SLC1A2,GPC5,ABLIM1,TRPS1,MAP3K5,MSI2,DTNA,HIF3A,AQP4,PTPRZ1,BMPR1B,NEBL,SLC4A4,GLIS3,RORA,PAMR1,SORBS1,LSAMP,NRG3,DCLK2
6.702e-03	-5.01	clear_cell_renal_cell_carcinoma	COSMIC cancer mutations	clear_cell_renal_cell_carcinoma	13924	46	16828	48	NRCAM,ABLIM1,SLC1A2,RPS6KA2,NKAIN3,MAP3K5,AQP4,NEBL,PTPRZ1,GLIS3,SORBS1,LSAMP,DPP10,CTNND2,CLU,SOX5,CPE,MACF1,PITPNC1,MGAT4C,FMN2,EFEMP1,NTRK2,TRPM3,PARD3,TRPS1,GPC5,NAV3,DTNA,MSI2,HIF3A,SLC4A4,BMPR1B,PAMR1,RORA,DCLK2,NRG3,SPON1,ATP13A4,ADCY2,GPM6A,ATP1A2,NPAS3,TNIK,CSGALNACT1,HPSE2
6.705e-03	-5.00	metal ion transmembrane transporter activity	molecular function	GO:0046873	442	5	18094	49	TRPM3,SLC1A2,SLC4A4,GPM6A,ATP1A2
6.783e-03	-4.99	ATPASE_E1_E2	prosite domains	PS00154	36	2	12186	42	ATP13A4,ATP1A2
6.812e-03	-4.99	regulation of myelination	biological process	GO:0031641	46	2	18204	49	PARD3,PTPRZ1
6.817e-03	-4.99	monoatomic cation transmembrane transporter activity	molecular function	GO:0008324	630	6	18094	49	ATP1A2,SLC4A4,GPM6A,ATP13A4,SLC1A2,TRPM3
6.881e-03	-4.98	TNIK (TRAF2 and NCK interacting kinase)	protein interactions	23043	151	3	19454	50	CLU,TNIK,MACF1
6.882e-03	-4.98	SPONDIN	prosite domains	PS51020	2	1	12186	42	SPON1
6.919e-03	-4.97	membrane raft	cellular component	GO:0045121	290	4	19108	50	ATP1A2,ADCY2,SLC1A2,SORBS1
6.997e-03	-4.96	Wnt signaling pathway	biological process	GO:0016055	283	4	18204	49	CTNND2,TNIK,MACF1,CPE
7.086e-03	-4.95	membrane microdomain	cellular component	GO:0098857	292	4	19108	50	SORBS1,ADCY2,SLC1A2,ATP1A2
7.099e-03	-4.95	Amyotrophic lateral sclerosis (ALS)	WikiPathways	WP2447	38	2	5310	18	MAP3K5,SLC1A2
7.103e-03	-4.95	Schwann cell differentiation	biological process	GO:0014037	47	2	18204	49	NTRK2,PARD3
7.103e-03	-4.95	regulation of neuron migration	biological process	GO:2001222	47	2	18204	49	CTNNA2,NRG3
7.110e-03	-4.95	acute_lymphoblastic_leukaemia	COSMIC cancer mutations	acute_lymphoblastic_leukaemia	2197	13	16828	48	TNIK,TRPS1,RPS6KA2,NTRK2,SLC4A4,PTPRZ1,BMPR1B,ATP1A2,DCLK2,DTNA,ADCY2,SOX5,MAP3K5
7.272e-03	-4.92	astrocytoma_Grade_I	COSMIC cancer mutations	astrocytoma_Grade_I	139	3	16828	48	PARD3,NRG3,GPC5
7.295e-03	-4.92	haematopoietic_and_lymphoid_tissue-small_intestine-lymphoid_neoplasm-enteropathy_type_T_cell_lymphoma	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue-small_intestine-lymphoid_neoplasm-enteropathy_type_T_cell_lymphoma	45	2	16828	48	MGAT4C,MACF1
7.295e-03	-4.92	enteropathy_type_T_cell_lymphoma	COSMIC cancer mutations	enteropathy_type_T_cell_lymphoma	45	2	16828	48	MGAT4C,MACF1
7.330e-03	-4.92	MAGI3 (membrane associated guanylate kinase, WW and PDZ domain containing 3)	protein interactions	260425	50	2	19454	50	NRCAM,PARD3
7.352e-03	-4.91	Vasopressin regulates renal water homeostasis via Aquaporins	REACTOME pathways	R-HSA-432040	43	2	10285	31	AQP4,ADCY2
7.396e-03	-4.91	CLa	smart domains	SM00035	2	1	9717	36	CLU
7.396e-03	-4.91	CLb	smart domains	SM00030	2	1	9717	36	CLU
7.525e-03	-4.89	CEP19 (centrosomal protein 19)	protein interactions	84984	156	3	19454	50	PARD3,ABLIM1,FMN2
7.617e-03	-4.88	FAM171B (family with sequence similarity 171 member B)	protein interactions	165215	51	2	19454	50	NTRK2,PARD3
7.631e-03	-4.88	human chr8q23.3	chromosome location	human chr8q23.3	4	1	26134	50	TRPS1
7.639e-03	-4.87	FORMIN	prints domains	PR00828	2	1	5227	20	FMN2
7.674e-03	-4.87	CATATPASE	prints domains	PR00119	35	2	5227	20	ATP1A2,ATP13A4
7.691e-03	-4.87	Plekhb1 (pleckstrin homology domain containing, family B (evectins) member 1)	protein interactions	27276	3	1	19454	50	BMPR1B
7.691e-03	-4.87	IL34 (interleukin 34)	protein interactions	146433	3	1	19454	50	PTPRZ1
7.691e-03	-4.87	Rb1cc1 (RB1-inducible coiled-coil 1)	protein interactions	12421	3	1	19454	50	MAP3K5
7.691e-03	-4.87	Rap2a (RAS related protein 2a)	protein interactions	76108	3	1	19454	50	BMPR1B
7.691e-03	-4.87	Chn1 (chimerin 1)	protein interactions	108699	3	1	19454	50	BMPR1B
7.691e-03	-4.87	Fbxw5 (F-box and WD-40 domain protein 5)	protein interactions	30839	3	1	19454	50	BMPR1B
7.691e-03	-4.87	Atg16l1 (autophagy related 16 like 1)	protein interactions	77040	3	1	19454	50	BMPR1B
7.691e-03	-4.87	Usp45 (ubiquitin specific petidase 45)	protein interactions	77593	3	1	19454	50	BMPR1B
7.691e-03	-4.87	Stk35 (serine/threonine kinase 35)	protein interactions	67333	3	1	19454	50	BMPR1B
7.691e-03	-4.87	Lep (leptin)	protein interactions	16846	3	1	19454	50	CLU
7.691e-03	-4.87	Gstm1 (glutathione S-transferase, mu 1)	protein interactions	14862	3	1	19454	50	MAP3K5
7.691e-03	-4.87	BCO1 (beta-carotene oxygenase 1)	protein interactions	53630	3	1	19454	50	ABLIM1
7.691e-03	-4.87	Spop (speckle-type BTB/POZ protein)	protein interactions	20747	3	1	19454	50	GLIS3
7.691e-03	-4.87	Smad6 (SMAD family member 6)	protein interactions	17130	3	1	19454	50	BMPR1B
7.749e-03	-4.86	purine ribonucleoside triphosphate binding	molecular function	GO:0035639	1804	11	18094	49	MAP3K5,RPS6KA2,ATP13A4,BMPR1B,TNIK,ATP1A2,MAPK10,NTRK2,NAV3,DCLK2,ADCY2
7.847e-03	-4.85	protein localization to membrane	biological process	GO:0072657	462	5	18204	49	TNIK,DPP10,CPE,PARD3,MACF1
7.909e-03	-4.84	AMHR2 (anti-Mullerian hormone receptor type 2)	protein interactions	269	52	2	19454	50	RPS6KA2,BMPR1B
7.909e-03	-4.84	SH2B2 (SH2B adaptor protein 2)	protein interactions	10603	52	2	19454	50	SORBS1,NTRK2
8.030e-03	-4.82	Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour	COSMIC cancer mutations	Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour	7434	30	16828	48	FMN2,CSGALNACT1,NPAS3,TNIK,SOX5,ATP13A4,ADCY2,MACF1,ATP1A2,CTNND2,RORA,GLIS3,PAMR1,SORBS1,NRG3,DCLK2,PTPRZ1,NEBL,SLC4A4,MAP3K5,DTNA,HIF3A,PARD3,TRPM3,NRCAM,NTRK2,NKAIN3,NAV3,TRPS1,ABLIM1
8.045e-03	-4.82	stomach-carcinoma	COSMIC cancer mutations	stomach-carcinoma	439	5	16828	48	BMPR1B,MAP3K5,NTRK2,RPS6KA2,TNIK
8.054e-03	-4.82	cysteine transmembrane transport	biological process	GO:1903712	3	1	18204	49	SLC1A2
8.054e-03	-4.82	radial glia guided migration of Purkinje cell	biological process	GO:0021942	3	1	18204	49	CTNNA2
8.054e-03	-4.82	regulation of calcium:sodium antiporter activity	biological process	GO:1903279	3	1	18204	49	ATP1A2
8.054e-03	-4.82	protein targeting to lysosome involved in chaperone-mediated autophagy	biological process	GO:0061740	3	1	18204	49	CLU
8.054e-03	-4.82	meiotic chromosome movement towards spindle pole	biological process	GO:0016344	3	1	18204	49	FMN2
8.054e-03	-4.82	UDP-N-acetylgalactosamine metabolic process	biological process	GO:0019276	3	1	18204	49	CSGALNACT1
8.054e-03	-4.82	cysteine transport	biological process	GO:0042883	3	1	18204	49	SLC1A2
8.054e-03	-4.82	mammary placode formation	biological process	GO:0060596	3	1	18204	49	NRG3
8.054e-03	-4.82	formin-nucleated actin cable organization	biological process	GO:0110009	3	1	18204	49	FMN2
8.054e-03	-4.82	cardiac muscle thin filament assembly	biological process	GO:0071691	3	1	18204	49	NEBL
8.054e-03	-4.82	immune complex clearance	biological process	GO:0002434	3	1	18204	49	CLU
8.054e-03	-4.82	trans-synaptic signaling by BDNF, modulating synaptic transmission	biological process	GO:0099183	3	1	18204	49	NTRK2
8.054e-03	-4.82	formin-nucleated actin cable assembly	biological process	GO:0070649	3	1	18204	49	FMN2
8.065e-03	-4.82	FBF1 (Fas binding factor 1)	protein interactions	85302	160	3	19454	50	ABLIM1,MAP3K5,SORBS1
8.078e-03	-4.82	MAP3K_TRAF-bd	interpro domains	IPR025136	3	1	18521	50	MAP3K5
8.078e-03	-4.82	HIF_alpha-like	interpro domains	IPR021537	3	1	18521	50	HIF3A
8.078e-03	-4.82	Reeler_sf	interpro domains	IPR042307	3	1	18521	50	SPON1
8.078e-03	-4.82	Vinculin_CS	interpro domains	IPR000633	3	1	18521	50	CTNNA2
8.078e-03	-4.82	MAP3K_PH	interpro domains	IPR043969	3	1	18521	50	MAP3K5
8.078e-03	-4.82	Myelin_PLP	interpro domains	IPR001614	3	1	18521	50	GPM6A
8.078e-03	-4.82	ROR_rcpt	interpro domains	IPR003079	3	1	18521	50	RORA
8.078e-03	-4.82	NTRK	interpro domains	IPR020777	3	1	18521	50	NTRK2
8.078e-03	-4.82	Nav/unc-53	interpro domains	IPR039041	3	1	18521	50	NAV3
8.078e-03	-4.82	NTRK_LRRCT	interpro domains	IPR031635	3	1	18521	50	NTRK2
8.078e-03	-4.82	HisK-N-like	interpro domains	IPR046873	3	1	18521	50	MAP3K5
8.078e-03	-4.82	SoHo_dom	interpro domains	IPR003127	3	1	18521	50	SORBS1
8.078e-03	-4.82	Reeler_dom	interpro domains	IPR002861	3	1	18521	50	SPON1
8.078e-03	-4.82	NR_DBD_ROR	interpro domains	IPR044101	3	1	18521	50	RORA
8.078e-03	-4.82	MAPK_JNK	interpro domains	IPR008351	3	1	18521	50	MAPK10
8.078e-03	-4.82	DRHyd-ASK	interpro domains	IPR046872	3	1	18521	50	MAP3K5
8.078e-03	-4.82	Myelin_PLP_CS	interpro domains	IPR018237	3	1	18521	50	GPM6A
8.078e-03	-4.82	Neuregulin	interpro domains	IPR040180	3	1	18521	50	NRG3
8.100e-03	-4.82	AFDN (afadin, adherens junction formation factor)	protein interactions	4301	309	4	19454	50	PARD3,SORBS1,MACF1,DTNA
8.103e-03	-4.82	alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity	molecular function	GO:0008454	3	1	18094	49	MGAT4C
8.103e-03	-4.82	cysteine transmembrane transporter activity	molecular function	GO:0033229	3	1	18094	49	SLC1A2
8.103e-03	-4.82	glucuronylgalactosylproteoglycan 4-beta-N-acetylgalactosaminyltransferase activity	molecular function	GO:0047237	3	1	18094	49	CSGALNACT1
8.103e-03	-4.82	epidermal growth factor receptor activity	molecular function	GO:0005006	3	1	18094	49	EFEMP1
8.103e-03	-4.82	JUN kinase activity	molecular function	GO:0004705	3	1	18094	49	MAPK10
8.131e-03	-4.81	upper_aerodigestive_tract-pharynx-carcinoma-squamous_cell_carcinoma	COSMIC cancer mutations	upper_aerodigestive_tract-pharynx-carcinoma-squamous_cell_carcinoma	1485	10	16828	48	FMN2,DTNA,SORBS1,MACF1,NRG3,PTPRZ1,NRCAM,NPAS3,EFEMP1,GPC5
8.238e-03	-4.80	MAP3K_TRAF_bd	pfam domains	PF13281	3	1	17795	49	MAP3K5
8.238e-03	-4.80	HIF-1	pfam domains	PF11413	3	1	17795	49	HIF3A
8.238e-03	-4.80	LRRCT_2	pfam domains	PF16920	3	1	17795	49	NTRK2
8.238e-03	-4.80	DRHyd-ASK	pfam domains	PF20309	3	1	17795	49	MAP3K5
8.238e-03	-4.80	SR_plectin_7	pfam domains	PF21097	3	1	17795	49	MACF1
8.238e-03	-4.80	HisK-N-like	pfam domains	PF20302	3	1	17795	49	MAP3K5
8.238e-03	-4.80	Sorb	pfam domains	PF02208	3	1	17795	49	SORBS1
8.238e-03	-4.80	ASK_PH	pfam domains	PF19039	3	1	17795	49	MAP3K5
8.238e-03	-4.80	Myelin_PLP	pfam domains	PF01275	3	1	17795	49	GPM6A
8.525e-03	-4.76	retina development in camera-type eye	biological process	GO:0060041	156	3	18204	49	BMPR1B,NTRK2,GPM6A
8.607e-03	-4.76	regulation of plasma membrane bounded cell projection organization	biological process	GO:0120035	666	6	18204	49	NTRK2,GPM6A,NRCAM,CTNNA2,TNIK,MACF1
8.748e-03	-4.74	ZYX (zyxin)	protein interactions	7791	316	4	19454	50	MACF1,NEBL,SORBS1,ABLIM1
8.917e-03	-4.72	SCLT1 (sodium channel and clathrin linker 1)	protein interactions	132320	166	3	19454	50	ABLIM1,NEBL,ATP1A2
8.972e-03	-4.71	sodium ion transmembrane transporter activity	molecular function	GO:0015081	158	3	18094	49	SLC1A2,SLC4A4,ATP1A2
9.066e-03	-4.70	ATPase-coupled monoatomic cation transmembrane transporter activity	molecular function	GO:0019829	53	2	18094	49	ATP1A2,ATP13A4
9.095e-03	-4.70	-	gene3d domains	6.10.250.2510	3	1	14470	44	CTNNA2
9.095e-03	-4.70	Reeler domain	gene3d domains	2.60.40.4060	3	1	14470	44	SPON1
9.125e-03	-4.70	CSTL1 (cystatin like 1)	protein interactions	128817	56	2	19454	50	CLU,CPE
9.125e-03	-4.70	L1CAM (L1 cell adhesion molecule)	protein interactions	3897	56	2	19454	50	RPS6KA2,GPM6A
9.290e-03	-4.68	negative regulation of supramolecular fiber organization	biological process	GO:1902904	161	3	18204	49	NAV3,CTNNA2,CLU
9.322e-03	-4.68	Angiopoietin Like Protein 8 Regulatory Pathway	WikiPathways	WP3915	132	3	5310	18	MAP3K5,MAPK10,RPS6KA2
9.401e-03	-4.67	postsynaptic density	cellular component	GO:0014069	317	4	19108	50	NTRK2,CTNND2,TNIK,NRCAM
9.665e-03	-4.64	PPFIBP1 (PPFIA binding protein 1)	protein interactions	8496	171	3	19454	50	PARD3,RPS6KA2,NTRK2
9.679e-03	-4.64	regulation of cell projection organization	biological process	GO:0031344	683	6	18204	49	GPM6A,NTRK2,MACF1,CTNNA2,TNIK,NRCAM
9.733e-03	-4.63	gallbladder	COSMIC cancer mutations	gallbladder	2821	15	16828	48	TRPS1,CTNND2,NKAIN3,CLU,DPP10,NRCAM,TRPM3,PARD3,MACF1,TNIK,SLC4A4,PITPNC1,PTPRZ1,NRG3,FMN2
9.733e-03	-4.63	biliary_tract-gallbladder-carcinoma-adenocarcinoma	COSMIC cancer mutations	biliary_tract-gallbladder-carcinoma-adenocarcinoma	2821	15	16828	48	FMN2,NRG3,PTPRZ1,PITPNC1,SLC4A4,TNIK,MACF1,PARD3,TRPM3,NRCAM,DPP10,NKAIN3,CLU,CTNND2,TRPS1
9.767e-03	-4.63	negative regulation of neuron apoptotic process	biological process	GO:0043524	164	3	18204	49	PTPRZ1,NTRK2,CLU
9.838e-03	-4.62	HER-positive_carcinoma	COSMIC cancer mutations	HER-positive_carcinoma	2025	12	16828	48	NRG3,RBMS3,MSI2,PAMR1,RORA,MAP3K5,ABLIM1,GPC5,RPS6KA2,NTRK2,NRCAM,BMPR1B
9.838e-03	-4.62	breast-carcinoma-HER-positive_carcinoma	COSMIC cancer mutations	breast-carcinoma-HER-positive_carcinoma	2025	12	16828	48	PAMR1,RORA,NRG3,RBMS3,BMPR1B,MSI2,MAP3K5,NTRK2,NRCAM,GPC5,ABLIM1,RPS6KA2
9.950e-03	-4.61	CAV1 (caveolin 1)	protein interactions	857	719	6	19454	50	FMN2,RPS6KA2,DTNA,TNIK,PARD3,MACF1
1.002e-02	-4.60	Znf_NHR/GATA	interpro domains	IPR013088	56	2	18521	50	RORA,TRPS1
1.007e-02	-4.60	regulation of cell differentiation	biological process	GO:0045595	1622	10	18204	49	MACF1,TRPS1,RORA,PTPRZ1,EFEMP1,BMPR1B,MAP3K5,NRCAM,NTRK2,SOX5
1.009e-02	-4.60	VEGFA (vascular endothelial growth factor A)	protein interactions	7422	59	2	19454	50	CLU,PTPRZ1
1.010e-02	-4.59	purine ribonucleotide binding	molecular function	GO:0032555	1871	11	18094	49	BMPR1B,NAV3,DCLK2,TNIK,ATP1A2,ATP13A4,RPS6KA2,MAP3K5,ADCY2,NTRK2,MAPK10
1.014e-02	-4.59	anion binding	molecular function	GO:0043168	2412	13	18094	49	MAP3K5,ATP13A4,RPS6KA2,PITPNC1,ATP1A2,TNIK,NTRK2,MAPK10,ADCY2,BMPR1B,PARD3,DCLK2,NAV3
1.023e-02	-4.58	Chondroitin sulfate/dermatan sulfate metabolism	REACTOME pathways	R-HSA-1793185	51	2	10285	31	GPC5,CSGALNACT1
1.023e-02	-4.58	positive regulation of cell differentiation	biological process	GO:0045597	906	7	18204	49	MACF1,BMPR1B,PTPRZ1,NRCAM,MAP3K5,SOX5,NTRK2
1.024e-02	-4.58	Naa20 (N(alpha)-acetyltransferase 20, NatB catalytic subunit)	protein interactions	67877	4	1	19454	50	BMPR1B
1.024e-02	-4.58	Cdk14 (cyclin dependent kinase 14)	protein interactions	18647	4	1	19454	50	BMPR1B
1.024e-02	-4.58	Dnaja1 (DnaJ heat shock protein family (Hsp40) member A1)	protein interactions	15502	4	1	19454	50	GLIS3
1.024e-02	-4.58	Nkiras1 (NFKB inhibitor interacting Ras-like protein 1)	protein interactions	69721	4	1	19454	50	BMPR1B
1.024e-02	-4.58	CCDC126 (coiled-coil domain containing 126)	protein interactions	90693	4	1	19454	50	GPM6A
1.024e-02	-4.58	Arhgef6 (Rac/Cdc42 guanine nucleotide exchange factor 6)	protein interactions	73341	4	1	19454	50	BMPR1B
1.024e-02	-4.58	Nme2 (NME/NM23 nucleoside diphosphate kinase 2)	protein interactions	18103	4	1	19454	50	RORA
1.024e-02	-4.58	Ilkap (integrin-linked kinase-associated serine/threonine phosphatase 2C)	protein interactions	67444	4	1	19454	50	BMPR1B
1.024e-02	-4.58	Rhebl1 (Ras homolog enriched in brain like 1)	protein interactions	69159	4	1	19454	50	BMPR1B
1.024e-02	-4.58	Srgap1 (SLIT-ROBO Rho GTPase activating protein 1)	protein interactions	117600	4	1	19454	50	BMPR1B
1.024e-02	-4.58	Ctbp2 (C-terminal binding protein 2)	protein interactions	13017	4	1	19454	50	TRPS1
1.029e-02	-4.58	SLC4A7 (solute carrier family 4 member 7)	protein interactions	9497	175	3	19454	50	SLC4A4,NTRK2,RPS6KA2
1.030e-02	-4.58	VINCULIN_1	prosite domains	PS00663	3	1	12186	42	CTNNA2
1.030e-02	-4.58	MYELIN_PLP_2	prosite domains	PS01004	3	1	12186	42	GPM6A
1.030e-02	-4.58	SOHO	prosite domains	PS50831	3	1	12186	42	SORBS1
1.030e-02	-4.58	MYELIN_PLP_1	prosite domains	PS00575	3	1	12186	42	GPM6A
1.030e-02	-4.58	REELIN	prosite domains	PS51019	3	1	12186	42	SPON1
1.031e-02	-4.58	dendritic spine	cellular component	GO:0043197	172	3	19108	50	GPM6A,ATP1A2,NTRK2
1.031e-02	-4.57	visual behavior	biological process	GO:0007632	57	2	18204	49	ATP1A2,SLC1A2
1.037e-02	-4.57	cellular component biogenesis	biological process	GO:0044085	2716	14	18204	49	NEBL,CLU,SORBS1,NRCAM,GPM6A,SLC1A2,TNIK,ABLIM1,RFX4,AQP4,FMN2,PARD3,NRG3,TRPM3
1.041e-02	-4.57	parathyroid-carcinoma	COSMIC cancer mutations	parathyroid-carcinoma	300	4	16828	48	PAMR1,MACF1,GPC5,TRPS1
1.043e-02	-4.56	IRE1-TRAF2-ASK1 complex	cellular component	GO:1990604	4	1	19108	50	MAP3K5
1.043e-02	-4.56	internode region of axon	cellular component	GO:0033269	4	1	19108	50	PARD3
1.049e-02	-4.56	Cellular responses to stress	REACTOME pathways	R-HSA-2262752	451	5	10285	31	TNIK,MAP3K5,HIF3A,MAPK10,RPS6KA2
1.053e-02	-4.55	side of membrane	cellular component	GO:0098552	715	6	19108	50	GPC5,NRCAM,AQP4,MAP3K5,DTNA,LSAMP
1.062e-02	-4.55	Aquaporin-mediated transport	REACTOME pathways	R-HSA-445717	52	2	10285	31	ADCY2,AQP4
1.063e-02	-4.54	neuron spine	cellular component	GO:0044309	174	3	19108	50	GPM6A,NTRK2,ATP1A2
1.066e-02	-4.54	JNK cascade	biological process	GO:0007254	58	2	18204	49	MAPK10,MAP3K5
1.072e-02	-4.54	regulation of glutamate uptake involved in transmission of nerve impulse	biological process	GO:0051946	4	1	18204	49	ATP1A2
1.072e-02	-4.54	brain-derived neurotrophic factor receptor signaling pathway	biological process	GO:0031547	4	1	18204	49	NTRK2
1.072e-02	-4.54	ovarian cumulus expansion	biological process	GO:0001550	4	1	18204	49	BMPR1B
1.072e-02	-4.54	positive regulation of mesenchymal stem cell differentiation	biological process	GO:2000741	4	1	18204	49	SOX5
1.072e-02	-4.54	protein localization to secretory granule	biological process	GO:0033366	4	1	18204	49	CPE
1.072e-02	-4.54	positive regulation of inclusion body assembly	biological process	GO:0090261	4	1	18204	49	CLU
1.072e-02	-4.54	response to glycoside	biological process	GO:1903416	4	1	18204	49	ATP1A2
1.072e-02	-4.54	trans-synaptic signaling by BDNF	biological process	GO:0099191	4	1	18204	49	NTRK2
1.072e-02	-4.54	regulation of amino acid uptake involved in synaptic transmission	biological process	GO:0051941	4	1	18204	49	ATP1A2
1.073e-02	-4.53	cell-cell junction	cellular component	GO:0005911	513	5	19108	50	SORBS1,CTNNA2,PARD3,CTNND2,ATP1A2
1.076e-02	-4.53	Neurofascin/L1/NrCAM_C	interpro domains	IPR026966	4	1	18521	50	NRCAM
1.076e-02	-4.53	Na/K-Atpase_Interacting	interpro domains	IPR008516	4	1	18521	50	NKAIN3
1.076e-02	-4.53	AbLIM_anchor	interpro domains	IPR032402	4	1	18521	50	ABLIM1
1.076e-02	-4.53	Alpha_catenin	interpro domains	IPR001033	4	1	18521	50	CTNNA2
1.076e-02	-4.53	Nebulin_repeat	interpro domains	IPR000900	4	1	18521	50	NEBL
1.076e-02	-4.53	PCN-like_spectrin-like_rpt	interpro domains	IPR049538	4	1	18521	50	MACF1
1.076e-02	-4.53	P5B-type_ATPase	interpro domains	IPR047821	4	1	18521	50	ATP13A4
1.076e-02	-4.53	TRPM_tetra	interpro domains	IPR032415	4	1	18521	50	TRPM3
1.076e-02	-4.53	P5A-ATPase_N	interpro domains	IPR047819	4	1	18521	50	ATP13A4
1.076e-02	-4.53	RSK_N	interpro domains	IPR041906	4	1	18521	50	RPS6KA2
1.076e-02	-4.53	Glyco_transf_54	interpro domains	IPR006759	4	1	18521	50	MGAT4C
1.076e-02	-4.53	TRPM_tetra_sf	interpro domains	IPR037162	4	1	18521	50	TRPM3
1.076e-02	-4.53	Desmoplakin_Spectrin-like	interpro domains	IPR041573	4	1	18521	50	MACF1
1.076e-02	-4.53	MAPK8IP3 (mitogen-activated protein kinase 8 interacting protein 3)	protein interactions	23162	61	2	19454	50	MAP3K5,MAPK10
1.077e-02	-4.53	oligodendroglioma_Grade_III	COSMIC cancer mutations	oligodendroglioma_Grade_III	303	4	16828	48	MGAT4C,GLIS3,PTPRZ1,MACF1
1.078e-02	-4.53	ribonucleotide binding	molecular function	GO:0032553	1888	11	18094	49	ADCY2,NAV3,DCLK2,NTRK2,MAPK10,TNIK,ATP1A2,BMPR1B,ATP13A4,RPS6KA2,MAP3K5
1.079e-02	-4.53	brain-derived neurotrophic factor binding	molecular function	GO:0048403	4	1	18094	49	NTRK2
1.084e-02	-4.52	lung-carcinoma-squamous_cell_carcinoma	COSMIC cancer mutations	lung-carcinoma-squamous_cell_carcinoma	14664	47	16828	48	ATP1A2,SPON1,ATP13A4,ADCY2,GPM6A,TNIK,NPAS3,HPSE2,CSGALNACT1,TRPS1,GPC5,NAV3,EFEMP1,NTRK2,TRPM3,PARD3,HIF3A,DTNA,MSI2,SLC4A4,BMPR1B,DCLK2,NRG3,PAMR1,RORA,CTNND2,CLU,DPP10,MACF1,SOX5,CPE,PITPNC1,MGAT4C,FMN2,RFX4,ABLIM1,SLC1A2,NKAIN3,RPS6KA2,NRCAM,AQP4,MAP3K5,NEBL,PTPRZ1,SORBS1,LSAMP,GLIS3
1.092e-02	-4.52	Corticotropin Activation of Cortisol Production	SMPDB pathways	SMP0000310	5	1	1369	3	ADCY2
1.097e-02	-4.51	Nebulin	pfam domains	PF00880	4	1	17795	49	NEBL
1.097e-02	-4.51	Spectrin_4	pfam domains	PF21020	4	1	17795	49	MACF1
1.097e-02	-4.51	Spectrin_2	pfam domains	PF18373	4	1	17795	49	MACF1
1.097e-02	-4.51	Spectrin_3	pfam domains	PF21019	4	1	17795	49	MACF1
1.097e-02	-4.51	TRPM_tetra	pfam domains	PF16519	4	1	17795	49	TRPM3
1.097e-02	-4.51	AbLIM_anchor	pfam domains	PF16182	4	1	17795	49	ABLIM1
1.097e-02	-4.51	Bravo_FIGEY	pfam domains	PF13882	4	1	17795	49	NRCAM
1.097e-02	-4.51	NKAIN	pfam domains	PF05640	4	1	17795	49	NKAIN3
1.097e-02	-4.51	Glyco_transf_54	pfam domains	PF04666	4	1	17795	49	MGAT4C
1.097e-02	-4.51	P5-ATPase	pfam domains	PF12409	4	1	17795	49	ATP13A4
1.101e-02	-4.51	MAPK signaling pathway	KEGG pathways	ko04010	255	4	7161	25	MAP3K5,RPS6KA2,MAPK10,NTRK2
1.101e-02	-4.51	MAPK signaling pathway	KEGG pathways	hsa04010	255	4	7161	25	MAP3K5,RPS6KA2,MAPK10,NTRK2
1.101e-02	-4.51	endochondral bone morphogenesis	biological process	GO:0060350	59	2	18204	49	CSGALNACT1,BMPR1B
1.106e-02	-4.50	chondroitin biosynthesis	BIOCYC pathways	META_PWY-6566	5	1	902	2	CSGALNACT1
1.107e-02	-4.50	Sorb	smart domains	SM00459	3	1	9717	36	SORBS1
1.107e-02	-4.50	PLP	smart domains	SM00002	3	1	9717	36	GPM6A
1.111e-02	-4.50	asymmetric synapse	cellular component	GO:0032279	333	4	19108	50	TNIK,NRCAM,CTNND2,NTRK2
1.113e-02	-4.50	cell migration	biological process	GO:0016477	921	7	18204	49	GPC5,NTRK2,GPM6A,FMN2,NRCAM,CTNNA2,NRG3
1.113e-02	-4.50	functioning	COSMIC cancer mutations	functioning	1803	11	16828	48	SLC1A2,TRPM3,NRCAM,NTRK2,EFEMP1,SOX5,PTPRZ1,HPSE2,NRG3,RFX4,FMN2
1.113e-02	-4.50	adrenal_gland-adrenal_gland-adrenal_cortical_carcinoma-functioning	COSMIC cancer mutations	adrenal_gland-adrenal_gland-adrenal_cortical_carcinoma-functioning	1803	11	16828	48	NTRK2,EFEMP1,PTPRZ1,NRCAM,TRPM3,SLC1A2,FMN2,RFX4,SOX5,NRG3,HPSE2
1.114e-02	-4.50	ovary-carcinoma-clear_cell_carcinoma	COSMIC cancer mutations	ovary-carcinoma-clear_cell_carcinoma	665	6	16828	48	DCLK2,MAP3K5,RPS6KA2,TNIK,BMPR1B,NTRK2
1.117e-02	-4.49	parathyroid	COSMIC cancer mutations	parathyroid	476	5	16828	48	MACF1,GPC5,TRPS1,GPM6A,PAMR1
1.121e-02	-4.49	YWHAB (tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein beta)	protein interactions	7529	965	7	19454	50	PITPNC1,PARD3,MAP3K5,DCLK2,MACF1,ABLIM1,SORBS1
1.128e-02	-4.48	cartilage development	biological process	GO:0051216	173	3	18204	49	BMPR1B,SOX5,CSGALNACT1
1.128e-02	-4.48	regulation of cell size	biological process	GO:0008361	173	3	18204	49	MACF1,NRCAM,AQP4
1.137e-02	-4.48	export across plasma membrane	biological process	GO:0140115	60	2	18204	49	SLC4A4,ATP1A2
1.137e-02	-4.48	proteoglycan biosynthetic process	biological process	GO:0030166	60	2	18204	49	CSGALNACT1,BMPR1B
1.137e-02	-4.48	regulation of glucose import	biological process	GO:0046324	60	2	18204	49	SLC1A2,SORBS1
1.141e-02	-4.47	Heparan sulfate/heparin (HS-GAG) metabolism	REACTOME pathways	R-HSA-1638091	54	2	10285	31	HPSE2,GPC5
1.143e-02	-4.47	human chr14q13.1	chromosome location	human chr14q13.1	6	1	26134	50	NPAS3
1.143e-02	-4.47	human chr4q34.2	chromosome location	human chr4q34.2	6	1	26134	50	GPM6A
1.144e-02	-4.47	MYELINPLP	prints domains	PR00214	3	1	5227	20	GPM6A
1.144e-02	-4.47	JNKMAPKINASE	prints domains	PR01772	3	1	5227	20	MAPK10
1.144e-02	-4.47	NTKRECEPTOR	prints domains	PR01939	3	1	5227	20	NTRK2
1.144e-02	-4.47	RORNUCRECPTR	prints domains	PR01293	3	1	5227	20	RORA
1.145e-02	-4.47	clear_cell_carcinoma	COSMIC cancer mutations	clear_cell_carcinoma	669	6	16828	48	RPS6KA2,TNIK,DCLK2,BMPR1B,MAP3K5,NTRK2
1.145e-02	-4.47	YWHAG (tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein gamma)	protein interactions	7532	1211	8	19454	50	DCLK2,FMN2,PITPNC1,PARD3,MAP3K5,MACF1,ABLIM1,SORBS1
1.161e-02	-4.46	MAPK9 (mitogen-activated protein kinase 9)	protein interactions	5601	183	3	19454	50	MACF1,MAPK10,CLU
1.165e-02	-4.45	metal ion binding	molecular function	GO:0046872	4239	19	18094	49	SLC1A2,EFEMP1,CSGALNACT1,BMPR1B,DTNA,MACF1,ADCY2,SPON1,TRPS1,GLIS3,PAMR1,CPE,ABLIM1,ATP1A2,MGAT4C,RORA,RPS6KA2,ATP13A4,MAP3K5
1.169e-02	-4.45	cell differentiation	biological process	GO:0030154	3645	17	18204	49	NEBL,CLU,RORA,BMPR1B,CTNNA2,NRCAM,NTRK2,MSI2,GPM6A,TNIK,CTNND2,PTPRZ1,FMN2,PARD3,SOX5,NAV3,DCLK2
1.179e-02	-4.44	cellular developmental process	biological process	GO:0048869	3648	17	18204	49	SOX5,NAV3,DCLK2,FMN2,PARD3,PTPRZ1,TNIK,CTNND2,NTRK2,MSI2,GPM6A,CTNNA2,NRCAM,BMPR1B,NEBL,CLU,RORA
1.187e-02	-4.43	lower_third	COSMIC cancer mutations	lower_third	7961	31	16828	48	SORBS1,NRG3,DCLK2,RORA,PAMR1,PTPRZ1,NEBL,SLC4A4,AQP4,MAP3K5,NAV3,RPS6KA2,TRPS1,GPC5,PARD3,TRPM3,NTRK2,EFEMP1,HPSE2,FMN2,MGAT4C,NPAS3,MACF1,ATP1A2,ADCY2,ATP13A4,SOX5,CPE,SPON1,CTNND2,DPP10
1.200e-02	-4.42	Astrocytic Glutamate-Glutamine Uptake And Metabolism	REACTOME pathways	R-HSA-210455	4	1	10285	31	SLC1A2
1.200e-02	-4.42	Neurotransmitter uptake and Metabolism In Glial Cells	REACTOME pathways	R-HSA-112313	4	1	10285	31	SLC1A2
1.202e-02	-4.42	serous_carcinoma	COSMIC cancer mutations	serous_carcinoma	10987	39	16828	48	TNIK,NPAS3,HPSE2,CSGALNACT1,MGAT4C,FMN2,CTNND2,CLU,DPP10,ATP1A2,MACF1,CPE,ADCY2,SOX5,ATP13A4,SLC4A4,NEBL,BMPR1B,PTPRZ1,DCLK2,NRG3,LSAMP,SORBS1,PAMR1,GLIS3,RORA,GPC5,TRPS1,SLC1A2,NAV3,RPS6KA2,EFEMP1,NTRK2,TRPM3,NRCAM,PARD3,DTNA,MSI2,MAP3K5
1.205e-02	-4.42	primitive_neuroectodermal_tumour-medulloblastoma	COSMIC cancer mutations	primitive_neuroectodermal_tumour-medulloblastoma	15350	48	16828	48	AQP4,MAP3K5,ABLIM1,NKAIN3,RPS6KA2,SLC1A2,NRCAM,SORBS1,LSAMP,GLIS3,PTPRZ1,NEBL,MACF1,SOX5,CPE,CLU,CTNND2,DPP10,MGAT4C,FMN2,RFX4,PITPNC1,HIF3A,MSI2,DTNA,GPC5,TRPS1,NAV3,NTRK2,EFEMP1,PARD3,TRPM3,NRG3,DCLK2,PAMR1,RORA,SLC4A4,BMPR1B,ATP1A2,SPON1,GPM6A,ATP13A4,ADCY2,HPSE2,RBMS3,CSGALNACT1,TNIK,NPAS3
1.211e-02	-4.41	TRPM, tetramerisation domain	gene3d domains	1.20.5.1010	4	1	14470	44	TRPM3
1.211e-02	-4.41	-	gene3d domains	1.20.58.1060	4	1	14470	44	MACF1
1.211e-02	-4.41	positive regulation of protein localization to plasma membrane	biological process	GO:1903078	62	2	18204	49	DPP10,SORBS1
1.215e-02	-4.41	PPP3R1 (protein phosphatase 3 regulatory subunit B, alpha)	protein interactions	5534	65	2	19454	50	GPM6A,MAP3K5
1.221e-02	-4.41	synapse organization	biological process	GO:0050808	333	4	18204	49	NRG3,NRCAM,CTNND2,GPM6A
1.221e-02	-4.41	inorganic molecular entity transmembrane transporter activity	molecular function	GO:0015318	714	6	18094	49	SLC4A4,GPM6A,ATP1A2,AQP4,TRPM3,SLC1A2
1.225e-02	-4.40	transmembrane receptor protein tyrosine kinase activity	molecular function	GO:0004714	62	2	18094	49	NTRK2,EFEMP1
1.245e-02	-4.39	camera-type eye development	biological process	GO:0043010	335	4	18204	49	GPM6A,EFEMP1,NTRK2,BMPR1B
1.250e-02	-4.38	cell adhesion	biological process	GO:0007155	942	7	18204	49	PARD3,SPON1,NRCAM,CTNNA2,SORBS1,CTNND2,LSAMP
1.253e-02	-4.38	postsynaptic specialization	cellular component	GO:0099572	345	4	19108	50	TNIK,NRCAM,NTRK2,CTNND2
1.254e-02	-4.38	Erythroid Transcription Factor GATA-1, subunit A	gene3d domains	3.30.50.10	56	2	14470	44	RORA,TRPS1
1.276e-02	-4.36	Fluid shear stress and atherosclerosis	KEGG pathways	hsa05418	142	3	7161	25	MAPK10,MAP3K5,BMPR1B
1.276e-02	-4.36	Fluid shear stress and atherosclerosis	KEGG pathways	ko05418	142	3	7161	25	BMPR1B,MAP3K5,MAPK10
1.279e-02	-4.36	DPP10 (dipeptidyl peptidase like 10)	protein interactions	57628	5	1	19454	50	DPP10
1.279e-02	-4.36	RFX4 (regulatory factor X4)	protein interactions	5992	5	1	19454	50	RFX4
1.279e-02	-4.36	Rnf166 (ring finger protein 166)	protein interactions	68718	5	1	19454	50	MAP3K5
1.279e-02	-4.36	TRPM6 (transient receptor potential cation channel subfamily M member 6)	protein interactions	140803	5	1	19454	50	TRPM3
1.279e-02	-4.36	Rhobtb1 (Rho-related BTB domain containing 1)	protein interactions	69288	5	1	19454	50	BMPR1B
1.279e-02	-4.36	ADCYAP1R1 (ADCYAP receptor type I)	protein interactions	117	5	1	19454	50	CLU
1.279e-02	-4.36	Rab6b (RAB6B, member RAS oncogene family)	protein interactions	270192	5	1	19454	50	BMPR1B
1.279e-02	-4.36	EPPIN (epididymal peptidase inhibitor)	protein interactions	57119	5	1	19454	50	CLU
1.279e-02	-4.36	Wwp2 (WW domain containing E3 ubiquitin protein ligase 2)	protein interactions	66894	5	1	19454	50	GLIS3
1.279e-02	-4.36	TRH (thyrotropin releasing hormone)	protein interactions	7200	5	1	19454	50	CPE
1.279e-02	-4.36	Rab38 (RAB38, member RAS oncogene family)	protein interactions	72433	5	1	19454	50	BMPR1B
1.279e-02	-4.36	Rhoj (ras homolog family member J)	protein interactions	80837	5	1	19454	50	BMPR1B
1.279e-02	-4.36	Rras2 (related RAS viral (r-ras) oncogene 2)	protein interactions	66922	5	1	19454	50	BMPR1B
1.279e-02	-4.36	Cdk4 (cyclin dependent kinase 4)	protein interactions	12567	5	1	19454	50	BMPR1B
1.279e-02	-4.36	SLC10A3 (solute carrier family 10 member 3)	protein interactions	8273	5	1	19454	50	SORBS1
1.287e-02	-4.35	actin filament bundle assembly	biological process	GO:0051017	64	2	18204	49	SORBS1,FMN2
1.287e-02	-4.35	cellular senescence	biological process	GO:0090398	64	2	18204	49	MAPK10,MAP3K5
1.287e-02	-4.35	dendrite morphogenesis	biological process	GO:0048813	64	2	18204	49	CTNNA2,CTNND2
1.292e-02	-4.35	central_nervous_system-brain-primitive_neuroectodermal_tumour-medulloblastoma-large_cell	COSMIC cancer mutations	central_nervous_system-brain-primitive_neuroectodermal_tumour-medulloblastoma-large_cell	1117	8	16828	48	ADCY2,ATP13A4,SOX5,FMN2,NRG3,PARD3,GPC5,SLC1A2
1.296e-02	-4.35	regulation of Wnt signaling pathway	biological process	GO:0030111	339	4	18204	49	GPC5,CTNND2,RBMS3,MACF1
1.302e-02	-4.34	neurofibrillary tangle	cellular component	GO:0097418	5	1	19108	50	CLU
1.304e-02	-4.34	SH3_9	pfam domains	PF14604	63	2	17795	49	SORBS1,NEBL
1.309e-02	-4.34	Ion transport by P-type ATPases	REACTOME pathways	R-HSA-936837	58	2	10285	31	ATP1A2,ATP13A4
1.310e-02	-4.34	Intracellular Signalling Through PGD2 receptor and Prostaglandin D2	SMPDB pathways	SMP0000343	6	1	1369	3	ADCY2
1.310e-02	-4.34	Dopamine Activation of Neurological Reward System	SMPDB pathways	SMP0000308	6	1	1369	3	ADCY2
1.312e-02	-4.33	regulation of carbohydrate metabolic process	biological process	GO:0006109	183	3	18204	49	SORBS1,SLC4A4,RORA
1.312e-02	-4.33	regulation of protein localization to membrane	biological process	GO:1905475	183	3	18204	49	DPP10,GPC5,SORBS1
1.324e-02	-4.32	PLCH1 (phospholipase C eta 1)	protein interactions	23007	68	2	19454	50	NTRK2,PARD3
1.324e-02	-4.32	SHROOM3 (shroom family member 3)	protein interactions	57619	68	2	19454	50	PARD3,RPS6KA2
1.324e-02	-4.32	CIB1 (calcium and integrin binding 1)	protein interactions	10519	68	2	19454	50	GLIS3,MAP3K5
1.325e-02	-4.32	regulation of protein processing	biological process	GO:0070613	65	2	18204	49	RFX4,SPON1
1.328e-02	-4.32	env (Envelope surface glycoprotein gp160, precursor)	protein interactions	155971	1501	9	19454	50	MAP3K5,ADCY2,CTNNA2,SLC1A2,NTRK2,MAPK10,MGAT4C,EFEMP1,BMPR1B
1.331e-02	-4.32	adenoid_cystic_carcinoma	COSMIC cancer mutations	adenoid_cystic_carcinoma	1123	8	16828	48	MAP3K5,RORA,MGAT4C,CTNND2,RPS6KA2,TNIK,NRCAM,NTRK2
1.332e-02	-4.32	human chr4q21.3	chromosome location	human chr4q21.3	7	1	26134	50	MAPK10
1.336e-02	-4.32	haematopoietic_and_lymphoid_tissue-spleen-lymphoid_neoplasm-marginal_zone_lymphoma	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue-spleen-lymphoid_neoplasm-marginal_zone_lymphoma	323	4	16828	48	PTPRZ1,MAP3K5,ADCY2,SORBS1
1.339e-02	-4.31	polar body extrusion after meiotic divisions	biological process	GO:0040038	5	1	18204	49	FMN2
1.339e-02	-4.31	positive regulation of amyloid fibril formation	biological process	GO:1905908	5	1	18204	49	CLU
1.339e-02	-4.31	amygdala development	biological process	GO:0021764	5	1	18204	49	ATP1A2
1.339e-02	-4.31	negative regulation of chondrocyte proliferation	biological process	GO:1902731	5	1	18204	49	BMPR1B
1.339e-02	-4.31	D-aspartate transmembrane transport	biological process	GO:0070777	5	1	18204	49	SLC1A2
1.339e-02	-4.31	central nervous system myelin maintenance	biological process	GO:0032286	5	1	18204	49	CLU
1.339e-02	-4.31	D-aspartate import across plasma membrane	biological process	GO:0070779	5	1	18204	49	SLC1A2
1.339e-02	-4.31	synaptic signaling via neuropeptide	biological process	GO:0099538	5	1	18204	49	NTRK2
1.341e-02	-4.31	oesophagus-lower_third-carcinoma-adenocarcinoma	COSMIC cancer mutations	oesophagus-lower_third-carcinoma-adenocarcinoma	6302	26	16828	48	GPC5,TRPS1,RPS6KA2,NAV3,EFEMP1,NTRK2,TRPM3,PARD3,AQP4,NEBL,PTPRZ1,NRG3,SORBS1,PAMR1,RORA,CTNND2,DPP10,MACF1,SPON1,CPE,SOX5,ATP13A4,ADCY2,NPAS3,MGAT4C,FMN2
1.343e-02	-4.31	Vinculin/catenin	interpro domains	IPR006077	5	1	18521	50	CTNNA2
1.343e-02	-4.31	P-type_TPase_V	interpro domains	IPR006544	5	1	18521	50	ATP13A4
1.343e-02	-4.31	Na/HCO3_transpt	interpro domains	IPR003024	5	1	18521	50	SLC4A4
1.343e-02	-4.31	PI_transfer	interpro domains	IPR001666	5	1	18521	50	PITPNC1
1.344e-02	-4.31	Amyotrophic lateral sclerosis (ALS)	KEGG pathways	ko05014	51	2	7161	25	MAP3K5,SLC1A2
1.344e-02	-4.31	Amyotrophic lateral sclerosis (ALS)	KEGG pathways	hsa05014	51	2	7161	25	SLC1A2,MAP3K5
1.347e-02	-4.31	neurotrophin receptor activity	molecular function	GO:0005030	5	1	18094	49	NTRK2
1.347e-02	-4.31	high-affinity L-glutamate transmembrane transporter activity	molecular function	GO:0005314	5	1	18094	49	SLC1A2
1.347e-02	-4.31	transforming growth factor beta receptor activity, type I	molecular function	GO:0005025	5	1	18094	49	BMPR1B
1.347e-02	-4.31	glutamate:sodium symporter activity	molecular function	GO:0015501	5	1	18094	49	SLC1A2
1.358e-02	-4.30	small_intestine-carcinoid-endocrine_tumour	COSMIC cancer mutations	small_intestine-carcinoid-endocrine_tumour	175	3	16828	48	TNIK,MACF1,CSGALNACT1
1.359e-02	-4.30	skin-head_neck-carcinoma-squamous_cell_carcinoma	COSMIC cancer mutations	skin-head_neck-carcinoma-squamous_cell_carcinoma	14191	46	16828	48	SLC4A4,BMPR1B,NRG3,DCLK2,PAMR1,RORA,TRPS1,GPC5,NAV3,NTRK2,EFEMP1,PARD3,TRPM3,HIF3A,DTNA,TNIK,NPAS3,HPSE2,CSGALNACT1,ATP1A2,SPON1,GPM6A,ATP13A4,ADCY2,PTPRZ1,NEBL,SORBS1,LSAMP,GLIS3,ABLIM1,RPS6KA2,NKAIN3,SLC1A2,NRCAM,AQP4,MAP3K5,PITPNC1,MGAT4C,RFX4,FMN2,CLU,CTNND2,DPP10,MACF1,CPE,SOX5
1.361e-02	-4.30	cellular component organization	biological process	GO:0016043	5636	23	18204	49	DCLK2,TRPM3,NRG3,FMN2,PTPRZ1,AQP4,RFX4,MACF1,TNIK,CTNND2,CSGALNACT1,CTNNA2,SORBS1,CLU,NEBL,PARD3,PITPNC1,ABLIM1,GPM6A,SLC1A2,HPSE2,NRCAM,BMPR1B
1.364e-02	-4.29	ERBB signaling pathway	biological process	GO:0038127	66	2	18204	49	NRG3,EFEMP1
1.369e-02	-4.29	Vinculin	pfam domains	PF01044	5	1	17795	49	CTNNA2
1.369e-02	-4.29	IP_trans	pfam domains	PF02121	5	1	17795	49	PITPNC1
1.372e-02	-4.29	NEBULIN	prosite domains	PS51216	4	1	12186	42	NEBL
1.386e-02	-4.28	kidney-other-neoplasm	COSMIC cancer mutations	kidney-other-neoplasm	10653	38	16828	48	TNIK,NPAS3,HPSE2,MGAT4C,CSGALNACT1,FMN2,RFX4,CTNND2,CLU,ATP1A2,MACF1,SPON1,CPE,ATP13A4,SOX5,ADCY2,GPM6A,NEBL,PTPRZ1,NRG3,SORBS1,LSAMP,PAMR1,RORA,TRPS1,GPC5,ABLIM1,SLC1A2,NAV3,NKAIN3,EFEMP1,NTRK2,NRCAM,TRPM3,PARD3,AQP4,DTNA,MAP3K5
1.388e-02	-4.28	oesophagus-lower_third-carcinoma-squamous_cell_carcinoma	COSMIC cancer mutations	oesophagus-lower_third-carcinoma-squamous_cell_carcinoma	3507	17	16828	48	HPSE2,DCLK2,FMN2,PTPRZ1,NPAS3,SLC4A4,MACF1,ATP1A2,MAP3K5,ADCY2,SPON1,NAV3,CTNND2,GPC5,PARD3,TRPM3,DPP10
1.399e-02	-4.27	PCDH20 (protocadherin 20)	protein interactions	64881	70	2	19454	50	CTNNA2,MGAT4C
1.425e-02	-4.25	DNAJC5 (DnaJ heat shock protein family (Hsp40) member C5)	protein interactions	80331	365	4	19454	50	PARD3,DTNA,MACF1,CLU
1.425e-02	-4.25	skin-ear-carcinoma-squamous_cell_carcinoma	COSMIC cancer mutations	skin-ear-carcinoma-squamous_cell_carcinoma	506	5	16828	48	RPS6KA2,NPAS3,MGAT4C,DPP10,MAP3K5
1.426e-02	-4.25	purine nucleotide binding	molecular function	GO:0017076	1964	11	18094	49	BMPR1B,DCLK2,NAV3,ATP13A4,RPS6KA2,MAP3K5,TNIK,ATP1A2,MAPK10,NTRK2,ADCY2
1.437e-02	-4.24	AKR7L (aldo-keto reductase family 7 like (gene/pseudogene))	protein interactions	246181	71	2	19454	50	PARD3,MACF1
1.437e-02	-4.24	MAP2K4 (mitogen-activated protein kinase kinase 4)	protein interactions	6416	71	2	19454	50	MAPK10,MAP3K5
1.440e-02	-4.24	salivary_gland	COSMIC cancer mutations	salivary_gland	1139	8	16828	48	NTRK2,NRCAM,TNIK,RPS6KA2,CTNND2,MGAT4C,RORA,MAP3K5
1.444e-02	-4.24	actin filament bundle organization	biological process	GO:0061572	68	2	18204	49	SORBS1,FMN2
1.450e-02	-4.23	marginal_zone_lymphoma	COSMIC cancer mutations	marginal_zone_lymphoma	331	4	16828	48	PTPRZ1,ADCY2,MAP3K5,SORBS1
1.466e-02	-4.22	CH	pfam domains	PF00307	67	2	17795	49	NAV3,MACF1
1.474e-02	-4.22	NEBU	smart domains	SM00227	4	1	9717	36	NEBL
1.476e-02	-4.22	DPYSL3 (dihydropyrimidinase like 3)	protein interactions	1809	72	2	19454	50	GPM6A,TNIK
1.476e-02	-4.22	Ppp1cb (protein phosphatase 1 catalytic subunit beta)	protein interactions	19046	72	2	19454	50	PARD3,ABLIM1
1.479e-02	-4.21	cell body	cellular component	GO:0044297	556	5	19108	50	GPM6A,BMPR1B,CTNND2,ATP1A2,SLC1A2
1.485e-02	-4.21	regulation of protein maturation	biological process	GO:1903317	69	2	18204	49	SPON1,RFX4
1.486e-02	-4.21	thyroid-carcinoma	COSMIC cancer mutations	thyroid-carcinoma	4126	19	16828	48	GLIS3,LSAMP,PTPRZ1,TNIK,ADCY2,SOX5,CPE,ATP13A4,DTNA,HIF3A,AQP4,MACF1,ATP1A2,PARD3,TRPM3,NAV3,CTNND2,TRPS1,GPC5
1.492e-02	-4.21	TIAM1 (TIAM Rac1 associated GEF 1)	protein interactions	7074	201	3	19454	50	PARD3,ATP1A2,DTNA
1.495e-02	-4.20	carbohydrate derivative binding	molecular function	GO:0097367	2251	12	18094	49	NAV3,DCLK2,ADCY2,MAPK10,NTRK2,BMPR1B,ATP1A2,TNIK,MAP3K5,RPS6KA2,ATP13A4,HPSE2
1.498e-02	-4.20	NGF-independant TRKA activation	REACTOME pathways	R-HSA-187024	5	1	10285	31	NTRK2
1.500e-02	-4.20	cation binding	molecular function	GO:0043169	4341	19	18094	49	SLC1A2,MACF1,DTNA,EFEMP1,BMPR1B,CSGALNACT1,CPE,ABLIM1,SPON1,ADCY2,PAMR1,GLIS3,TRPS1,RORA,MAP3K5,ATP13A4,RPS6KA2,MGAT4C,ATP1A2
1.504e-02	-4.20	bone-Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour	COSMIC cancer mutations	bone-Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour	6023	25	16828	48	CTNND2,MACF1,ATP1A2,ADCY2,ATP13A4,SOX5,NPAS3,CSGALNACT1,NKAIN3,NAV3,ABLIM1,PARD3,TRPM3,NRCAM,NTRK2,MAP3K5,DTNA,PTPRZ1,NEBL,SLC4A4,NRG3,DCLK2,GLIS3,RORA,PAMR1
1.512e-02	-4.19	neuron to neuron synapse	cellular component	GO:0098984	365	4	19108	50	CTNND2,NTRK2,TNIK,NRCAM
1.522e-02	-4.19	ALPHACATENIN	prints domains	PR00805	4	1	5227	20	CTNNA2
1.526e-02	-4.18	large_intestine-caecum-carcinoma-adenocarcinoma	COSMIC cancer mutations	large_intestine-caecum-carcinoma-adenocarcinoma	14236	46	16828	48	HPSE2,CSGALNACT1,TNIK,NPAS3,ATP1A2,SPON1,ATP13A4,ADCY2,GPM6A,DCLK2,NRG3,PAMR1,RORA,SLC4A4,BMPR1B,HIF3A,DTNA,TRPS1,GPC5,NAV3,EFEMP1,NTRK2,TRPM3,PARD3,MGAT4C,FMN2,RFX4,PITPNC1,MACF1,SOX5,CPE,CTNND2,CLU,DPP10,LSAMP,SORBS1,GLIS3,NEBL,PTPRZ1,AQP4,MAP3K5,ABLIM1,SLC1A2,NKAIN3,RPS6KA2,NRCAM
1.526e-02	-4.18	transporter activity	molecular function	GO:0005215	1211	8	18094	49	AQP4,TRPM3,SLC1A2,ATP13A4,SLC4A4,GPM6A,PITPNC1,ATP1A2
1.527e-02	-4.18	Vasopressin Regulation of Water Homeostasis	SMPDB pathways	SMP0000322	7	1	1369	3	ADCY2
1.532e-02	-4.18	CYRIA (CYFIP related Rac1 interactor A)	protein interactions	81553	6	1	19454	50	GPM6A
1.532e-02	-4.18	GDF6 (growth differentiation factor 6)	protein interactions	392255	6	1	19454	50	BMPR1B
1.532e-02	-4.18	SOX1 (SRY-box transcription factor 1)	protein interactions	6656	6	1	19454	50	SOX5
1.532e-02	-4.18	DRP2 (dystrophin related protein 2)	protein interactions	1821	6	1	19454	50	DTNA
1.532e-02	-4.18	Rhod (ras homolog family member D)	protein interactions	11854	6	1	19454	50	BMPR1B
1.532e-02	-4.18	SOX11 (SRY-box transcription factor 11)	protein interactions	6664	6	1	19454	50	SOX5
1.532e-02	-4.18	Rara (retinoic acid receptor, alpha)	protein interactions	19401	6	1	19454	50	MAPK10
1.532e-02	-4.18	Itch (itchy, E3 ubiquitin protein ligase)	protein interactions	16396	6	1	19454	50	GLIS3
1.532e-02	-4.18	ADCY1 (adenylate cyclase 1)	protein interactions	107	6	1	19454	50	ADCY2
1.532e-02	-4.18	Fancl (Fanconi anemia, complementation group L)	protein interactions	67030	6	1	19454	50	BMPR1B
1.532e-02	-4.18	SLC12A5 (solute carrier family 12 member 5)	protein interactions	57468	6	1	19454	50	GPM6A
1.532e-02	-4.18	Zbtb2 (zinc finger and BTB domain containing 2)	protein interactions	381990	6	1	19454	50	SORBS1
1.532e-02	-4.18	Tiam2 (T cell lymphoma invasion and metastasis 2)	protein interactions	24001	6	1	19454	50	DTNA
1.532e-02	-4.18	Taok2 (TAO kinase 2)	protein interactions	381921	6	1	19454	50	CLU
1.532e-02	-4.18	Map2k3 (mitogen-activated protein kinase kinase 3)	protein interactions	26397	6	1	19454	50	BMPR1B
1.538e-02	-4.17	prostate-adenoma	COSMIC cancer mutations	prostate-adenoma	1634	10	16828	48	SOX5,MACF1,HIF3A,DCLK2,NEBL,TRPM3,PTPRZ1,PARD3,NPAS3,GPC5
1.544e-02	-4.17	monoatomic ion transmembrane transporter activity	molecular function	GO:0015075	752	6	18094	49	GPM6A,SLC4A4,ATP1A2,ATP13A4,TRPM3,SLC1A2
1.550e-02	-4.17	LIM	pfam domains	PF00412	69	2	17795	49	NEBL,ABLIM1
1.551e-02	-4.17	pancreas-carcinoma-adenocarcinoma	COSMIC cancer mutations	pancreas-carcinoma-adenocarcinoma	517	5	16828	48	NEBL,MACF1,HPSE2,DCLK2,GPC5
1.554e-02	-4.16	TNF receptor signaling pathway	Pathway Interaction DB	tnfpathway	44	2	2226	10	MAP3K5,TNIK
1.560e-02	-4.16	PAR polarity complex	cellular component	GO:0120157	6	1	19108	50	PARD3
1.568e-02	-4.16	localization within membrane	biological process	GO:0051668	549	5	18204	49	TNIK,CPE,PARD3,MACF1,DPP10
1.573e-02	-4.15	caecum	COSMIC cancer mutations	caecum	14248	46	16828	48	CLU,CTNND2,DPP10,MACF1,SOX5,CPE,PITPNC1,RFX4,FMN2,MGAT4C,RPS6KA2,NKAIN3,SLC1A2,ABLIM1,NRCAM,AQP4,MAP3K5,PTPRZ1,NEBL,LSAMP,SORBS1,GLIS3,ATP1A2,GPM6A,ATP13A4,ADCY2,SPON1,TNIK,NPAS3,HPSE2,CSGALNACT1,NAV3,GPC5,TRPS1,PARD3,TRPM3,NTRK2,EFEMP1,HIF3A,DTNA,BMPR1B,SLC4A4,NRG3,DCLK2,RORA,PAMR1
1.576e-02	-4.15	Znf_LIM	interpro domains	IPR001781	71	2	18521	50	NEBL,ABLIM1
1.578e-02	-4.15	MAP kinase activation in TLR cascade	REACTOME pathways	R-HSA-450294	64	2	10285	31	RPS6KA2,MAPK10
1.586e-02	-4.14	Hippo signaling pathway	KEGG pathways	ko04390	154	3	7161	25	CTNNA2,BMPR1B,PARD3
1.586e-02	-4.14	Hippo signaling pathway	KEGG pathways	hsa04390	154	3	7161	25	PARD3,CTNNA2,BMPR1B
1.597e-02	-4.14	protein localization to plasma membrane	biological process	GO:0072659	197	3	18204	49	DPP10,MACF1,TNIK
1.604e-02	-4.13	fused antrum stage	biological process	GO:0048165	6	1	18204	49	BMPR1B
1.604e-02	-4.13	intracellular water homeostasis	biological process	GO:0009992	6	1	18204	49	AQP4
1.604e-02	-4.13	ERBB4-ERBB4 signaling pathway	biological process	GO:0038138	6	1	18204	49	NRG3
1.604e-02	-4.13	establishment of meiotic spindle localization	biological process	GO:0051295	6	1	18204	49	FMN2
1.604e-02	-4.13	clustering of voltage-gated sodium channels	biological process	GO:0045162	6	1	18204	49	NRCAM
1.604e-02	-4.13	D-amino acid transport	biological process	GO:0042940	6	1	18204	49	SLC1A2
1.604e-02	-4.13	protein targeting to vacuole involved in autophagy	biological process	GO:0071211	6	1	18204	49	CLU
1.604e-02	-4.13	L-aspartate import across plasma membrane	biological process	GO:0140009	6	1	18204	49	SLC1A2
1.604e-02	-4.13	asymmetric neuroblast division	biological process	GO:0055059	6	1	18204	49	SOX5
1.604e-02	-4.13	mammary gland formation	biological process	GO:0060592	6	1	18204	49	NRG3
1.609e-02	-4.13	TSP1_spondin_dom	interpro domains	IPR044004	6	1	18521	50	SPON1
1.609e-02	-4.13	Glypican_CS	interpro domains	IPR019803	6	1	18521	50	GPC5
1.609e-02	-4.13	Desmoplakin_SH3	interpro domains	IPR041615	6	1	18521	50	MACF1
1.609e-02	-4.13	Adcy_conserved_dom	interpro domains	IPR009398	6	1	18521	50	ADCY2
1.609e-02	-4.13	Glypican	interpro domains	IPR001863	6	1	18521	50	GPC5
1.609e-02	-4.13	EF-hand_dom_typ2	interpro domains	IPR015154	6	1	18521	50	DTNA
1.609e-02	-4.13	GAR_dom_sf	interpro domains	IPR036534	6	1	18521	50	MACF1
1.609e-02	-4.13	Ribosomal_S6_kinase_II	interpro domains	IPR016239	6	1	18521	50	RPS6KA2
1.609e-02	-4.13	GAR_dom	interpro domains	IPR003108	6	1	18521	50	MACF1
1.609e-02	-4.13	P-type_ATPase_IIC	interpro domains	IPR005775	6	1	18521	50	ATP1A2
1.609e-02	-4.13	Peptidase_S9B_N	interpro domains	IPR002469	6	1	18521	50	DPP10
1.609e-02	-4.13	EF-hand_dom_typ1	interpro domains	IPR015153	6	1	18521	50	DTNA
1.609e-02	-4.13	GLI-like	interpro domains	IPR043359	6	1	18521	50	GLIS3
1.614e-02	-4.13	glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity	molecular function	GO:0047238	6	1	18094	49	CSGALNACT1
1.614e-02	-4.13	steroid hormone binding	molecular function	GO:1990239	6	1	18094	49	ATP1A2
1.614e-02	-4.13	sodium:bicarbonate symporter activity	molecular function	GO:0008510	6	1	18094	49	SLC4A4
1.615e-02	-4.13	prostate-carcinoma-adenocarcinoma	COSMIC cancer mutations	prostate-carcinoma-adenocarcinoma	12379	42	16828	48	NAV3,NKAIN3,SLC1A2,ABLIM1,TRPS1,GPC5,PARD3,NRCAM,TRPM3,NTRK2,EFEMP1,HIF3A,AQP4,MAP3K5,PTPRZ1,NEBL,BMPR1B,SORBS1,LSAMP,NRG3,RORA,GLIS3,PAMR1,CLU,CTNND2,DPP10,MACF1,ATP1A2,GPM6A,CPE,ATP13A4,SOX5,ADCY2,SPON1,TNIK,PITPNC1,NPAS3,HPSE2,RFX4,FMN2,MGAT4C,CSGALNACT1
1.624e-02	-4.12	Sudden Infant Death Syndrome (SIDS) Susceptibility Pathways	WikiPathways	WP706	162	3	5310	18	AQP4,NTRK2,RORA
1.629e-02	-4.12	MKRN2 (makorin ring finger protein 2)	protein interactions	23609	380	4	19454	50	BMPR1B,PARD3,NRCAM,MACF1
1.634e-02	-4.11	system process	biological process	GO:0003008	2015	11	18204	49	SLC4A4,ATP1A2,PTPRZ1,AQP4,EFEMP1,ABLIM1,SLC1A2,NTRK2,CTNNA2,NRCAM,DTNA
1.641e-02	-4.11	EF-hand_3	pfam domains	PF09069	6	1	17795	49	DTNA
1.641e-02	-4.11	Plectin	pfam domains	PF00681	6	1	17795	49	MACF1
1.641e-02	-4.11	DPPIV_N	pfam domains	PF00930	6	1	17795	49	DPP10
1.641e-02	-4.11	TSP1_spondin	pfam domains	PF19028	6	1	17795	49	SPON1
1.641e-02	-4.11	Glypican	pfam domains	PF01153	6	1	17795	49	GPC5
1.641e-02	-4.11	Adcy_cons_dom	pfam domains	PF06327	6	1	17795	49	ADCY2
1.641e-02	-4.11	SH3_10	pfam domains	PF17902	6	1	17795	49	MACF1
1.641e-02	-4.11	GAS2	pfam domains	PF02187	6	1	17795	49	MACF1
1.641e-02	-4.11	EF-hand_2	pfam domains	PF09068	6	1	17795	49	DTNA
1.652e-02	-4.10	peptide metabolic process	biological process	GO:0006518	73	2	18204	49	CPE,SLC1A2
1.654e-02	-4.10	MACF1 (microtubule actin crosslinking factor 1)	protein interactions	23499	209	3	19454	50	RPS6KA2,NRCAM,TNIK
1.670e-02	-4.09	KIF20A (kinesin family member 20A)	protein interactions	10112	1044	7	19454	50	NEBL,MSI2,PARD3,MACF1,ABLIM1,RORA,NAV3
1.676e-02	-4.09	Htt (huntingtin)	protein interactions	15194	77	2	19454	50	GPM6A,LSAMP
1.692e-02	-4.08	breast-carcinoma-ductal_carcinoma	COSMIC cancer mutations	breast-carcinoma-ductal_carcinoma	14824	47	16828	48	TNIK,NPAS3,HPSE2,RBMS3,ATP1A2,SPON1,ADCY2,ATP13A4,GPM6A,SLC4A4,BMPR1B,DCLK2,NRG3,PAMR1,RORA,GPC5,TRPS1,NAV3,EFEMP1,NTRK2,TRPM3,PARD3,HIF3A,DTNA,MSI2,PITPNC1,MGAT4C,RFX4,FMN2,CTNND2,CLU,DPP10,MACF1,CPE,SOX5,NEBL,PTPRZ1,SORBS1,LSAMP,GLIS3,ABLIM1,SLC1A2,NKAIN3,RPS6KA2,NRCAM,AQP4,MAP3K5
1.695e-02	-4.08	positive regulation of protein localization to cell periphery	biological process	GO:1904377	74	2	18204	49	DPP10,SORBS1
1.696e-02	-4.08	CDK6 (cyclin dependent kinase 6)	protein interactions	1021	211	3	19454	50	SORBS1,MAP3K5,SOX5
1.705e-02	-4.07	HAD_sf	interpro domains	IPR023214	74	2	18521	50	ATP1A2,ATP13A4
1.709e-02	-4.07	human chr4q22.3	chromosome location	human chr4q22.3	9	1	26134	50	BMPR1B
1.717e-02	-4.06	Nedd4 (NEDD4 E3 ubiquitin protein ligase)	protein interactions	25489	78	2	19454	50	NTRK2,BMPR1B
1.717e-02	-4.06	ATP2B3 (ATPase plasma membrane Ca2+ transporting 3)	protein interactions	492	78	2	19454	50	GPM6A,CSGALNACT1
1.717e-02	-4.06	ANKRD40 (ankyrin repeat domain 40)	protein interactions	91369	78	2	19454	50	MSI2,SOX5
1.744e-02	-4.05	Intracellular Signalling Through Prostacyclin Receptor and Prostacyclin	SMPDB pathways	SMP0000354	8	1	1369	3	ADCY2
1.767e-02	-4.04	mannosyl-glycoprotein N-acetylglucosaminyltransferases	BIOCYC pathways	META_PWY-7426	8	1	902	2	MGAT4C
1.771e-02	-4.03	intracellular signal transduction	biological process	GO:0035556	1505	9	18204	49	MAPK10,ADCY2,TNIK,RPS6KA2,DCLK2,MAP3K5,FMN2,NRG3,ATP1A2
1.782e-02	-4.03	regulation of axon extension	biological process	GO:0030516	76	2	18204	49	MACF1,NRCAM
1.786e-02	-4.03	CYP4F8 (cytochrome P450 family 4 subfamily F member 8)	protein interactions	11283	7	1	19454	50	CLU
1.786e-02	-4.03	SOAT2 (sterol O-acyltransferase 2)	protein interactions	8435	7	1	19454	50	CLU
1.786e-02	-4.03	Smad7 (SMAD family member 7)	protein interactions	17131	7	1	19454	50	BMPR1B
1.786e-02	-4.03	Fbxo3 (F-box protein 3)	protein interactions	57443	7	1	19454	50	BMPR1B
1.786e-02	-4.03	Smurf1 (SMAD specific E3 ubiquitin protein ligase 1)	protein interactions	75788	7	1	19454	50	GLIS3
1.786e-02	-4.03	SASH3 (SAM and SH3 domain containing 3)	protein interactions	54440	7	1	19454	50	BMPR1B
1.786e-02	-4.03	RGMB (repulsive guidance molecule BMP co-receptor b)	protein interactions	285704	7	1	19454	50	BMPR1B
1.786e-02	-4.03	C8B (complement C8 beta chain)	protein interactions	732	7	1	19454	50	CLU
1.786e-02	-4.03	Uhmk1 (U2AF homology motif (UHM) kinase 1)	protein interactions	16589	7	1	19454	50	BMPR1B
1.786e-02	-4.03	ABCC12 (ATP binding cassette subfamily C member 12)	protein interactions	94160	7	1	19454	50	NPAS3
1.786e-02	-4.03	SLC16A5 (solute carrier family 16 member 5)	protein interactions	9121	7	1	19454	50	PTPRZ1
1.786e-02	-4.03	C7 (complement C7)	protein interactions	730	7	1	19454	50	CLU
1.795e-02	-4.02	RSK activation	REACTOME pathways	R-HSA-444257	6	1	10285	31	RPS6KA2
1.795e-02	-4.02	Activation of TRKA receptors	REACTOME pathways	R-HSA-187015	6	1	10285	31	NTRK2
1.811e-02	-4.01	Dipeptidylpeptidase IV, N-terminal domain	gene3d domains	2.140.10.30	6	1	14470	44	DPP10
1.811e-02	-4.01	Plakin repeat	gene3d domains	3.90.1290.10	6	1	14470	44	MACF1
1.811e-02	-4.01	Gas2-like domain	gene3d domains	3.30.920.20	6	1	14470	44	MACF1
1.820e-02	-4.01	catalytic activity, acting on a protein	molecular function	GO:0140096	2312	12	18094	49	NTRK2,CPE,MAPK10,TNIK,MGAT4C,DPP10,MAP3K5,PTPRZ1,RPS6KA2,DCLK2,EFEMP1,BMPR1B
1.826e-02	-4.00	GFAP (glial fibrillary acidic protein)	protein interactions	2670	217	3	19454	50	RORA,ABLIM1,NKAIN3
1.827e-02	-4.00	neural retina development	biological process	GO:0003407	77	2	18204	49	NTRK2,GPM6A
1.827e-02	-4.00	positive regulation of axonogenesis	biological process	GO:0050772	77	2	18204	49	MACF1,NTRK2
1.858e-02	-3.99	skin-nipple-malignant_melanoma	COSMIC cancer mutations	skin-nipple-malignant_melanoma	197	3	16828	48	FMN2,BMPR1B,EFEMP1
1.858e-02	-3.99	nipple	COSMIC cancer mutations	nipple	197	3	16828	48	EFEMP1,BMPR1B,FMN2
1.860e-02	-3.98	acral_lentiginous	COSMIC cancer mutations	acral_lentiginous	745	6	16828	48	MACF1,NAV3,NRG3,ATP13A4,PARD3,CSGALNACT1
1.869e-02	-3.98	chaperone-mediated autophagy	biological process	GO:0061684	7	1	18204	49	CLU
1.869e-02	-3.98	interneuron migration from the subpallium to the cortex	biological process	GO:0021830	7	1	18204	49	NRG3
1.869e-02	-3.98	negative regulation of Arp2/3 complex-mediated actin nucleation	biological process	GO:0034316	7	1	18204	49	CTNNA2
1.869e-02	-3.98	regulation of oligodendrocyte progenitor proliferation	biological process	GO:0070445	7	1	18204	49	PTPRZ1
1.869e-02	-3.98	post-embryonic eye morphogenesis	biological process	GO:0048050	7	1	18204	49	EFEMP1
1.869e-02	-3.98	chromosome movement towards spindle pole	biological process	GO:0051305	7	1	18204	49	FMN2
1.869e-02	-3.98	parallel actin filament bundle assembly	biological process	GO:0030046	7	1	18204	49	FMN2
1.872e-02	-3.98	dicarboxylic acid transport	biological process	GO:0006835	78	2	18204	49	NTRK2,SLC1A2
1.872e-02	-3.98	positive regulation of carbohydrate metabolic process	biological process	GO:0045913	78	2	18204	49	SLC4A4,SORBS1
1.872e-02	-3.98	regulation of glucose transmembrane transport	biological process	GO:0010827	78	2	18204	49	SLC1A2,SORBS1
1.875e-02	-3.98	Plakin_repeat_sf	interpro domains	IPR035915	7	1	18521	50	MACF1
1.875e-02	-3.98	Alpha-catenin/vinculin-like_sf	interpro domains	IPR036723	7	1	18521	50	CTNNA2
1.875e-02	-3.98	GS_dom	interpro domains	IPR003605	7	1	18521	50	BMPR1B
1.875e-02	-3.98	Na:dicarbo_symporter_sf	interpro domains	IPR036458	7	1	18521	50	SLC1A2
1.875e-02	-3.98	Na-dicarboxylate_symporter	interpro domains	IPR001991	7	1	18521	50	SLC1A2
1.875e-02	-3.98	Plectin_repeat	interpro domains	IPR001101	7	1	18521	50	MACF1
1.875e-02	-3.98	Na-dicarboxylate_symporter_CS	interpro domains	IPR018107	7	1	18521	50	SLC1A2
1.875e-02	-3.98	Plakophilin/d_Catenin	interpro domains	IPR028435	7	1	18521	50	CTNND2
1.875e-02	-3.98	Hud_Sxl_RNA	interpro domains	IPR002343	7	1	18521	50	RBMS3
1.875e-02	-3.98	Aquaporin_transptr	interpro domains	IPR034294	7	1	18521	50	AQP4
1.881e-02	-3.97	LBD domain binding	molecular function	GO:0050693	7	1	18094	49	SPON1
1.881e-02	-3.97	ribosomal protein S6 kinase activity	molecular function	GO:0004711	7	1	18094	49	RPS6KA2
1.881e-02	-3.97	P-type sodium:potassium-exchanging transporter activity	molecular function	GO:0005391	7	1	18094	49	ATP1A2
1.881e-02	-3.97	P-type sodium transporter activity	molecular function	GO:0008554	7	1	18094	49	ATP1A2
1.881e-02	-3.97	phosphatidic acid transfer activity	molecular function	GO:1990050	7	1	18094	49	PITPNC1
1.882e-02	-3.97	HAD-like_sf	interpro domains	IPR036412	78	2	18521	50	ATP1A2,ATP13A4
1.886e-02	-3.97	GSC (goosecoid homeobox)	protein interactions	145258	82	2	19454	50	SOX5,TRPS1
1.893e-02	-3.97	femur	COSMIC cancer mutations	femur	1197	8	16828	48	PTPRZ1,SLC4A4,GPC5,ADCY2,FMN2,SPON1,HPSE2,NRG3
1.897e-02	-3.96	human chr9p24.2	chromosome location	human chr9p24.2	10	1	26134	50	GLIS3
1.899e-02	-3.96	PITRANSFER	prints domains	PR00391	5	1	5227	20	PITPNC1
1.899e-02	-3.96	NAHCO3TRSPRT	prints domains	PR01232	5	1	5227	20	SLC4A4
1.909e-02	-3.96	eye development	biological process	GO:0001654	381	4	18204	49	BMPR1B,NTRK2,EFEMP1,GPM6A
1.912e-02	-3.96	SDF	pfam domains	PF00375	7	1	17795	49	SLC1A2
1.912e-02	-3.96	TGF_beta_GS	pfam domains	PF08515	7	1	17795	49	BMPR1B
1.917e-02	-3.95	haematopoietic_and_lymphoid_tissue-haematopoietic_neoplasm-acute_myeloid_leukaemia	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue-haematopoietic_neoplasm-acute_myeloid_leukaemia	10418	37	16828	48	FMN2,RFX4,CSGALNACT1,RBMS3,HPSE2,NPAS3,TNIK,ADCY2,CPE,ATP13A4,SOX5,SPON1,MACF1,ATP1A2,DPP10,CTNND2,RORA,GLIS3,PAMR1,LSAMP,NRG3,NEBL,PTPRZ1,SLC4A4,MAP3K5,MSI2,HIF3A,TRPM3,PARD3,EFEMP1,NTRK2,SLC1A2,RPS6KA2,NAV3,NKAIN3,GPC5,ABLIM1
1.917e-02	-3.95	acute_myeloid_leukaemia	COSMIC cancer mutations	acute_myeloid_leukaemia	10418	37	16828	48	HIF3A,MSI2,MAP3K5,ABLIM1,GPC5,SLC1A2,NAV3,RPS6KA2,NKAIN3,EFEMP1,NTRK2,TRPM3,PARD3,NRG3,LSAMP,PAMR1,RORA,GLIS3,SLC4A4,NEBL,PTPRZ1,ATP1A2,MACF1,SPON1,CPE,ADCY2,ATP13A4,SOX5,CTNND2,DPP10,HPSE2,RBMS3,CSGALNACT1,FMN2,RFX4,TNIK,NPAS3
1.918e-02	-3.95	leg	COSMIC cancer mutations	leg	969	7	16828	48	PTPRZ1,NEBL,SLC4A4,FMN2,ATP13A4,HIF3A,NRG3
1.925e-02	-3.95	RHOB (ras homolog family member B)	protein interactions	388	832	6	19454	50	ABLIM1,MACF1,PARD3,TNIK,DTNA,FMN2
1.961e-02	-3.93	Intracellular Signalling Through Histamine H2 Receptor and Histamine	SMPDB pathways	SMP0000335	9	1	1369	3	ADCY2
1.961e-02	-3.93	Excitatory Neural Signalling Through 5-HTR 6 and Serotonin	SMPDB pathways	SMP0000312	9	1	1369	3	ADCY2
1.961e-02	-3.93	Intracellular Signalling Through FSH Receptor and Follicle Stimulating Hormone	SMPDB pathways	SMP0000333	9	1	1369	3	ADCY2
1.961e-02	-3.93	Excitatory Neural Signalling Through 5-HTR 4 and Serotonin	SMPDB pathways	SMP0000309	9	1	1369	3	ADCY2
1.961e-02	-3.93	Excitatory Neural Signalling Through 5-HTR 7 and Serotonin	SMPDB pathways	SMP0000311	9	1	1369	3	ADCY2
1.966e-02	-3.93	eye-uveal_tract-malignant_melanoma-spindle	COSMIC cancer mutations	eye-uveal_tract-malignant_melanoma-spindle	363	4	16828	48	CTNND2,MACF1,CPE,TRPM3
1.976e-02	-3.92	visual system development	biological process	GO:0150063	385	4	18204	49	GPM6A,BMPR1B,NTRK2,EFEMP1
1.985e-02	-3.92	MAPRE3 (microtubule associated protein RP/EB family member 3)	protein interactions	22924	224	3	19454	50	MACF1,ABLIM1,GPM6A
1.985e-02	-3.92	solute:sodium symporter activity	molecular function	GO:0015370	80	2	18094	49	SLC1A2,SLC4A4
1.989e-02	-3.92	plasma membrane protein complex	cellular component	GO:0098797	600	5	19108	50	SORBS1,DPP10,CTNNA2,BMPR1B,ATP1A2
1.996e-02	-3.91	caveola	cellular component	GO:0005901	83	2	19108	50	SORBS1,ATP1A2
2.018e-02	-3.90	CFAP298 (cilia and flagella associated protein 298)	protein interactions	56683	85	2	19454	50	FMN2,TRPS1
2.020e-02	-3.90	SOX2 (SRY-box transcription factor 2)	protein interactions	6657	1342	8	19454	50	MSI2,NAV3,CLU,SOX5,TRPS1,GLIS3,LSAMP,MACF1
2.021e-02	-3.90	CH_dom	interpro domains	IPR001715	81	2	18521	50	NAV3,MACF1
2.023e-02	-3.90	monoatomic ion transmembrane transport	biological process	GO:0034220	804	6	18204	49	ATP13A4,ATP1A2,TRPM3,SLC1A2,GPM6A,SLC4A4
2.038e-02	-3.89	Rasd2 (RASD family, member 2)	protein interactions	75141	8	1	19454	50	BMPR1B
2.038e-02	-3.89	BMP15 (bone morphogenetic protein 15)	protein interactions	9210	8	1	19454	50	BMPR1B
2.038e-02	-3.89	Melk (maternal embryonic leucine zipper kinase)	protein interactions	17279	8	1	19454	50	MAP3K5
2.038e-02	-3.89	Chmp2a (charged multivesicular body protein 2A)	protein interactions	68953	8	1	19454	50	CLU
2.038e-02	-3.89	CCK (cholecystokinin)	protein interactions	885	8	1	19454	50	CPE
2.038e-02	-3.89	INSM1 (INSM transcriptional repressor 1)	protein interactions	3642	8	1	19454	50	SORBS1
2.038e-02	-3.89	Rps27a (ribosomal protein S27A)	protein interactions	78294	8	1	19454	50	BMPR1B
2.051e-02	-3.89	GAR	prosite domains	PS51460	6	1	12186	42	MACF1
2.051e-02	-3.89	GLYPICAN	prosite domains	PS01207	6	1	12186	42	GPC5
2.060e-02	-3.88	Tight junction	KEGG pathways	ko04530	170	3	7161	25	PARD3,MAPK10,MAP3K5
2.060e-02	-3.88	Tight junction	KEGG pathways	hsa04530	170	3	7161	25	MAPK10,PARD3,MAP3K5
2.063e-02	-3.88	FAM171A1 (family with sequence similarity 171 member A1)	protein interactions	221061	86	2	19454	50	NTRK2,PARD3
2.063e-02	-3.88	SYNJ1 (synaptojanin 1)	protein interactions	8867	86	2	19454	50	GPM6A,SORBS1
2.067e-02	-3.88	lobular_carcinoma	COSMIC cancer mutations	lobular_carcinoma	763	6	16828	48	TNIK,RPS6KA2,NTRK2,BMPR1B,DCLK2,MAP3K5
2.067e-02	-3.88	breast-carcinoma-lobular_carcinoma	COSMIC cancer mutations	breast-carcinoma-lobular_carcinoma	763	6	16828	48	MAP3K5,DCLK2,NTRK2,BMPR1B,TNIK,RPS6KA2
2.068e-02	-3.88	CH_dom_sf	interpro domains	IPR036872	82	2	18521	50	MACF1,NAV3
2.072e-02	-3.88	Cysteine Rich Protein	gene3d domains	2.10.110.10	73	2	14470	44	NEBL,ABLIM1
2.075e-02	-3.88	zonula adherens	cellular component	GO:0005915	8	1	19108	50	SORBS1
2.075e-02	-3.88	spherical high-density lipoprotein particle	cellular component	GO:0034366	8	1	19108	50	CLU
2.075e-02	-3.88	HFE-transferrin receptor complex	cellular component	GO:1990712	8	1	19108	50	BMPR1B
2.077e-02	-3.87	Glycosaminoglycan biosynthesis, chondroitin sulfate backbone	KEGG pathways	hsa_M00058	6	1	7161	25	CSGALNACT1
2.077e-02	-3.87	Glycosaminoglycan biosynthesis, chondroitin sulfate backbone	KEGG pathways	M00058	6	1	7161	25	CSGALNACT1
2.078e-02	-3.87	sensory system development	biological process	GO:0048880	391	4	18204	49	EFEMP1,NTRK2,BMPR1B,GPM6A
2.078e-02	-3.87	non_small_cell_carcinoma	COSMIC cancer mutations	non_small_cell_carcinoma	5198	22	16828	48	NPAS3,PTPRZ1,BMPR1B,PITPNC1,TNIK,RORA,DCLK2,LSAMP,NTRK2,PARD3,TRPS1,ABLIM1,CLU,RPS6KA2,NAV3,CTNND2,MSI2,MAP3K5,SOX5,ATP13A4,ADCY2,HIF3A
2.078e-02	-3.87	lung-carcinoma-non_small_cell_carcinoma	COSMIC cancer mutations	lung-carcinoma-non_small_cell_carcinoma	5198	22	16828	48	DCLK2,LSAMP,RORA,BMPR1B,PTPRZ1,HIF3A,MSI2,MAP3K5,ABLIM1,TRPS1,NAV3,RPS6KA2,NTRK2,PARD3,TNIK,NPAS3,PITPNC1,SOX5,ATP13A4,ADCY2,CTNND2,CLU
2.091e-02	-3.87	NrCAM interactions	REACTOME pathways	R-HSA-447038	7	1	10285	31	NRCAM
2.091e-02	-3.87	CREB phosphorylation	REACTOME pathways	R-HSA-199920	7	1	10285	31	RPS6KA2
2.091e-02	-3.87	Neurofascin interactions	REACTOME pathways	R-HSA-447043	7	1	10285	31	NRCAM
2.103e-02	-3.86	VANGL1 (VANGL planar cell polarity protein 1)	protein interactions	81839	229	3	19454	50	PARD3,NTRK2,RPS6KA2
2.109e-02	-3.86	inorganic cation transmembrane transporter activity	molecular function	GO:0022890	589	5	18094	49	SLC4A4,GPM6A,ATP1A2,TRPM3,SLC1A2
2.110e-02	-3.86	Sodium:dicarboxylate symporter	gene3d domains	1.10.3860.10	7	1	14470	44	SLC1A2
2.121e-02	-3.85	acinar_carcinoma	COSMIC cancer mutations	acinar_carcinoma	1978	11	16828	48	SOX5,FMN2,CSGALNACT1,SPON1,ATP1A2,BMPR1B,TRPM3,PTPRZ1,DPP10,CTNND2,NAV3
2.121e-02	-3.85	pancreas-carcinoma-acinar_carcinoma	COSMIC cancer mutations	pancreas-carcinoma-acinar_carcinoma	1978	11	16828	48	DPP10,BMPR1B,TRPM3,PTPRZ1,CTNND2,NAV3,CSGALNACT1,SPON1,SOX5,FMN2,ATP1A2
2.125e-02	-3.85	HAD superfamily/HAD-like	gene3d domains	3.40.50.1000	74	2	14470	44	ATP13A4,ATP1A2
2.126e-02	-3.85	skin-neck-malignant_melanoma	COSMIC cancer mutations	skin-neck-malignant_melanoma	1223	8	16828	48	TRPM3,DPP10,CTNND2,GPC5,ATP13A4,ADCY2,MAP3K5,ATP1A2
2.130e-02	-3.85	salivary_gland-parotid-carcinoma-adenoid_cystic_carcinoma	COSMIC cancer mutations	salivary_gland-parotid-carcinoma-adenoid_cystic_carcinoma	561	5	16828	48	NTRK2,MAP3K5,NRCAM,TNIK,RPS6KA2
2.134e-02	-3.85	regulation of L-glutamate import across plasma membrane	biological process	GO:0002036	8	1	18204	49	ATP1A2
2.134e-02	-3.85	insulin processing	biological process	GO:0030070	8	1	18204	49	CPE
2.134e-02	-3.85	ERBB4 signaling pathway	biological process	GO:0038130	8	1	18204	49	NRG3
2.134e-02	-3.85	regulation of synapse structural plasticity	biological process	GO:0051823	8	1	18204	49	CTNNA2
2.134e-02	-3.85	meiotic cytokinesis	biological process	GO:0033206	8	1	18204	49	FMN2
2.134e-02	-3.85	cerebellar granule cell precursor proliferation	biological process	GO:0021930	8	1	18204	49	RORA
2.134e-02	-3.85	cell proliferation in hindbrain	biological process	GO:0021534	8	1	18204	49	RORA
2.134e-02	-3.85	cell proliferation in external granule layer	biological process	GO:0021924	8	1	18204	49	RORA
2.134e-02	-3.85	dermatan sulfate proteoglycan biosynthetic process	biological process	GO:0050651	8	1	18204	49	CSGALNACT1
2.134e-02	-3.85	heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process	biological process	GO:0015014	8	1	18204	49	CSGALNACT1
2.134e-02	-3.85	protein import	biological process	GO:0017038	8	1	18204	49	CLU
2.140e-02	-3.84	RFX-like	interpro domains	IPR039779	8	1	18521	50	RFX4
2.140e-02	-3.84	Adcy	interpro domains	IPR030672	8	1	18521	50	ADCY2
2.140e-02	-3.84	Plakin	interpro domains	IPR043197	8	1	18521	50	MACF1
2.140e-02	-3.84	Villin_headpiece_dom_sf	interpro domains	IPR036886	8	1	18521	50	ABLIM1
2.140e-02	-3.84	Chond_GalNAc	interpro domains	IPR008428	8	1	18521	50	CSGALNACT1
2.140e-02	-3.84	TRPM_SLOG	interpro domains	IPR041491	8	1	18521	50	TRPM3
2.140e-02	-3.84	AC_N	interpro domains	IPR032628	8	1	18521	50	ADCY2
2.140e-02	-3.84	Villin_headpiece	interpro domains	IPR003128	8	1	18521	50	ABLIM1
2.146e-02	-3.84	BMP receptor activity	molecular function	GO:0098821	8	1	18094	49	BMPR1B
2.146e-02	-3.84	sodium ion binding	molecular function	GO:0031402	8	1	18094	49	ATP1A2
2.146e-02	-3.84	P-type potassium transmembrane transporter activity	molecular function	GO:0008556	8	1	18094	49	ATP1A2
2.147e-02	-3.84	cellular component organization or biogenesis	biological process	GO:0071840	5850	23	18204	49	CSGALNACT1,CTNNA2,CLU,NEBL,SORBS1,NRG3,FMN2,DCLK2,TRPM3,RFX4,MACF1,TNIK,CTNND2,PTPRZ1,AQP4,NRCAM,SLC1A2,GPM6A,HPSE2,BMPR1B,PARD3,ABLIM1,PITPNC1
2.151e-02	-3.84	regulation of sodium ion transport	biological process	GO:0002028	84	2	18204	49	NKAIN3,ATP1A2
2.151e-02	-3.84	peripheral nervous system development	biological process	GO:0007422	84	2	18204	49	NTRK2,PARD3
2.151e-02	-3.84	proteoglycan metabolic process	biological process	GO:0006029	84	2	18204	49	CSGALNACT1,BMPR1B
2.153e-02	-3.84	RAP2A (RAP2A, member of RAS oncogene family)	protein interactions	5911	88	2	19454	50	TNIK,BMPR1B
2.157e-02	-3.84	FYN (FYN proto-oncogene, Src family tyrosine kinase)	protein interactions	2534	414	4	19454	50	NTRK2,RPS6KA2,PTPRZ1,CTNND2
2.175e-02	-3.83	PRKAA2 (protein kinase AMP-activated catalytic subunit alpha 2)	protein interactions	5563	232	3	19454	50	MAP3K5,PARD3,SLC4A4
2.177e-02	-3.83	Intracellular Signalling Through LHCGR Receptor and Luteinizing Hormone/Choriogonadotropin	SMPDB pathways	SMP0000338	10	1	1369	3	ADCY2
2.182e-02	-3.82	AC_N	pfam domains	PF16214	8	1	17795	49	ADCY2
2.182e-02	-3.82	VHP	pfam domains	PF02209	8	1	17795	49	ABLIM1
2.182e-02	-3.82	DCX	pfam domains	PF03607	8	1	17795	49	DCLK2
2.182e-02	-3.82	CHGN	pfam domains	PF05679	8	1	17795	49	CSGALNACT1
2.182e-02	-3.82	LSDAT_euk	pfam domains	PF18139	8	1	17795	49	TRPM3
2.185e-02	-3.82	MAPK cascade	biological process	GO:0000165	222	3	18204	49	TNIK,MAP3K5,MAPK10
2.190e-02	-3.82	Axon guidance	KEGG pathways	hsa04360	174	3	7161	25	PARD3,ABLIM1,BMPR1B
2.190e-02	-3.82	Axon guidance	KEGG pathways	ko04360	174	3	7161	25	ABLIM1,BMPR1B,PARD3
2.199e-02	-3.82	chondrocyte differentiation	biological process	GO:0002062	85	2	18204	49	BMPR1B,SOX5
2.202e-02	-3.82	neck	COSMIC cancer mutations	neck	1231	8	16828	48	ATP13A4,MAP3K5,ADCY2,ATP1A2,TRPM3,DPP10,CTNND2,GPC5
2.203e-02	-3.82	GAS2	smart domains	SM00243	6	1	9717	36	MACF1
2.203e-02	-3.82	SH3_domain	interpro domains	IPR001452	222	3	18521	50	SORBS1,MACF1,NEBL
2.246e-02	-3.80	CTDSPL (CTD small phosphatase like)	protein interactions	10217	90	2	19454	50	DTNA,FMN2
2.247e-02	-3.80	central nervous system neuron development	biological process	GO:0021954	86	2	18204	49	NTRK2,DCLK2
2.272e-02	-3.78	human chr11p15.2	chromosome location	human chr11p15.2	12	1	26134	50	SPON1
2.272e-02	-3.78	human chr3p24.1	chromosome location	human chr3p24.1	12	1	26134	50	RBMS3
2.275e-02	-3.78	ACTIVIN2R	prints domains	PR00653	6	1	5227	20	BMPR1B
2.290e-02	-3.78	NEGR1 (neuronal growth regulator 1)	protein interactions	257194	9	1	19454	50	LSAMP
2.290e-02	-3.78	Tyw3 (tRNA-yW synthesizing protein 3 homolog (S. cerevisiae))	protein interactions	209584	9	1	19454	50	CTNNA2
2.290e-02	-3.78	LSAMP (limbic system associated membrane protein)	protein interactions	4045	9	1	19454	50	LSAMP
2.290e-02	-3.78	BIN2 (bridging integrator 2)	protein interactions	51411	9	1	19454	50	EFEMP1
2.290e-02	-3.78	ZNF778 (zinc finger protein 778)	protein interactions	197320	9	1	19454	50	EFEMP1
2.290e-02	-3.78	VEPH1 (ventricular zone expressed PH domain containing 1)	protein interactions	79674	9	1	19454	50	BMPR1B
2.290e-02	-3.78	CUX2 (cut like homeobox 2)	protein interactions	23316	9	1	19454	50	NAV3
2.290e-02	-3.78	NRXN2 (neurexin 2)	protein interactions	9379	9	1	19454	50	MACF1
2.292e-02	-3.78	SOS1 (SOS Ras/Rac guanine nucleotide exchange factor 1)	protein interactions	6654	91	2	19454	50	TNIK,SORBS1
2.292e-02	-3.78	THUMPD3 (THUMP domain containing 3)	protein interactions	25917	91	2	19454	50	RPS6KA2,CTNND2
2.292e-02	-3.78	TRIO (trio Rho guanine nucleotide exchange factor)	protein interactions	7204	91	2	19454	50	PARD3,NAV3
2.316e-02	-3.77	Epithelial cell signaling in Helicobacter pylori infection	KEGG pathways	hsa05120	68	2	7161	25	PTPRZ1,MAPK10
2.316e-02	-3.77	Epithelial cell signaling in Helicobacter pylori infection	KEGG pathways	ko05120	68	2	7161	25	MAPK10,PTPRZ1
2.322e-02	-3.76	single-stranded RNA binding	molecular function	GO:0003727	87	2	18094	49	RBMS3,MSI2
2.331e-02	-3.76	flotillin complex	cellular component	GO:0016600	9	1	19108	50	SORBS1
2.331e-02	-3.76	astrocyte end-foot	cellular component	GO:0097450	9	1	19108	50	AQP4
2.341e-02	-3.75	upper_aerodigestive_tract-mouth-carcinoma-adenoid_cystic_carcinoma	COSMIC cancer mutations	upper_aerodigestive_tract-mouth-carcinoma-adenoid_cystic_carcinoma	383	4	16828	48	MAP3K5,NTRK2,RPS6KA2,TNIK
2.341e-02	-3.75	salivary_gland-carcinoma	COSMIC cancer mutations	salivary_gland-carcinoma	383	4	16828	48	TNIK,RPS6KA2,NTRK2,MAP3K5
2.341e-02	-3.75	upper_aerodigestive_tract-head_neck-carcinoma-adenoid_cystic_carcinoma	COSMIC cancer mutations	upper_aerodigestive_tract-head_neck-carcinoma-adenoid_cystic_carcinoma	383	4	16828	48	RPS6KA2,TNIK,MAP3K5,NTRK2
2.341e-02	-3.75	upper_aerodigestive_tract-carcinoma	COSMIC cancer mutations	upper_aerodigestive_tract-carcinoma	383	4	16828	48	TNIK,RPS6KA2,NTRK2,MAP3K5
2.341e-02	-3.75	upper_aerodigestive_tract-lymph_node-carcinoma-adenoid_cystic_carcinoma	COSMIC cancer mutations	upper_aerodigestive_tract-lymph_node-carcinoma-adenoid_cystic_carcinoma	383	4	16828	48	NTRK2,MAP3K5,TNIK,RPS6KA2
2.341e-02	-3.75	skeletal system morphogenesis	biological process	GO:0048705	228	3	18204	49	CSGALNACT1,SOX5,BMPR1B
2.366e-02	-3.74	TRAF6 (TNF receptor associated factor 6)	protein interactions	7189	426	4	19454	50	TNIK,MAP3K5,NTRK2,BMPR1B
2.378e-02	-3.74	magnesium ion binding	molecular function	GO:0000287	228	3	18094	49	RPS6KA2,MAP3K5,ADCY2
2.387e-02	-3.74	Release of Hh-Np from the secreting cell	REACTOME pathways	R-HSA-5362798	8	1	10285	31	GPC5
2.387e-02	-3.74	ARHGEF6 (Rac/Cdc42 guanine nucleotide exchange factor 6)	protein interactions	9459	93	2	19454	50	BMPR1B,ABLIM1
2.387e-02	-3.74	parotid	COSMIC cancer mutations	parotid	578	5	16828	48	NRCAM,MAP3K5,NTRK2,RPS6KA2,TNIK
2.388e-02	-3.73	GS	prosite domains	PS51256	7	1	12186	42	BMPR1B
2.388e-02	-3.73	NA_DICARBOXYL_SYMP_1	prosite domains	PS00713	7	1	12186	42	SLC1A2
2.388e-02	-3.73	NA_DICARBOXYL_SYMP_2	prosite domains	PS00714	7	1	12186	42	SLC1A2
2.391e-02	-3.73	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-NK-T_cell_lymphoma	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-NK-T_cell_lymphoma	217	3	16828	48	MGAT4C,DTNA,RFX4
2.393e-02	-3.73	NAD+ Signalling and Aging	SMPDB pathways	SMP0084271	11	1	1369	3	RORA
2.397e-02	-3.73	microglial cell proliferation	biological process	GO:0061518	9	1	18204	49	CLU
2.397e-02	-3.73	negative regulation of striated muscle contraction	biological process	GO:0045988	9	1	18204	49	ATP1A2
2.397e-02	-3.73	macrophage proliferation	biological process	GO:0061517	9	1	18204	49	CLU
2.397e-02	-3.73	polyamine transmembrane transport	biological process	GO:1902047	9	1	18204	49	ATP13A4
2.397e-02	-3.73	hindbrain radial glia guided cell migration	biological process	GO:0021932	9	1	18204	49	CTNNA2
2.397e-02	-3.73	negative regulation of actin nucleation	biological process	GO:0051126	9	1	18204	49	CTNNA2
2.400e-02	-3.73	spindle	COSMIC cancer mutations	spindle	386	4	16828	48	CPE,TRPM3,MACF1,CTNND2
2.401e-02	-3.73	ERBIN (erbb2 interacting protein)	protein interactions	55914	241	3	19454	50	CTNND2,NTRK2,PARD3
2.401e-02	-3.73	Calponin-like domain	gene3d domains	1.10.418.10	79	2	14470	44	MACF1,NAV3
2.404e-02	-3.73	DNA-bd_RFX	interpro domains	IPR003150	9	1	18521	50	RFX4
2.404e-02	-3.73	Doublecortin_dom	interpro domains	IPR003533	9	1	18521	50	DCLK2
2.404e-02	-3.73	Band3_cytoplasmic_dom	interpro domains	IPR013769	9	1	18521	50	SLC4A4
2.404e-02	-3.73	Peptidase_S9	interpro domains	IPR001375	9	1	18521	50	DPP10
2.404e-02	-3.73	Activin_recp	interpro domains	IPR000472	9	1	18521	50	BMPR1B
2.407e-02	-3.73	Villin headpiece domain	gene3d domains	1.10.950.10	8	1	14470	44	ABLIM1
2.435e-02	-3.72	WWC1 (WW and C2 domain containing 1)	protein interactions	23286	94	2	19454	50	ABLIM1,TNIK
2.435e-02	-3.72	TTR (transthyretin)	protein interactions	7276	94	2	19454	50	CLU,CTNND2
2.448e-02	-3.71	Ion channel transport	REACTOME pathways	R-HSA-983712	209	3	10285	31	ATP1A2,TRPM3,ATP13A4
2.449e-02	-3.71	connective tissue development	biological process	GO:0061448	232	3	18204	49	BMPR1B,SOX5,CSGALNACT1
2.452e-02	-3.71	Activin_recp	pfam domains	PF01064	9	1	17795	49	BMPR1B
2.452e-02	-3.71	Band_3_cyto	pfam domains	PF07565	9	1	17795	49	SLC4A4
2.452e-02	-3.71	RFX_DNA_binding	pfam domains	PF02257	9	1	17795	49	RFX4
2.452e-02	-3.71	Peptidase_S9	pfam domains	PF00326	9	1	17795	49	DPP10
2.464e-02	-3.70	nucleotide binding	molecular function	GO:0000166	2128	11	18094	49	ATP13A4,RPS6KA2,MAP3K5,ATP1A2,TNIK,NTRK2,MAPK10,ADCY2,BMPR1B,NAV3,DCLK2
2.468e-02	-3.70	CH	smart domains	SM00033	66	2	9717	36	MACF1,NAV3
2.470e-02	-3.70	EGF-like_dom	interpro domains	IPR000742	232	3	18521	50	EFEMP1,PAMR1,NRG3
2.472e-02	-3.70	nucleoside phosphate binding	molecular function	GO:1901265	2129	11	18094	49	MAPK10,NTRK2,ADCY2,MAP3K5,RPS6KA2,ATP13A4,TNIK,ATP1A2,DCLK2,NAV3,BMPR1B
2.480e-02	-3.70	LIM_DOMAIN_1	prosite domains	PS00478	71	2	12186	42	ABLIM1,NEBL
2.480e-02	-3.70	LIM_DOMAIN_2	prosite domains	PS50023	71	2	12186	42	ABLIM1,NEBL
2.531e-02	-3.68	uveal_tract	COSMIC cancer mutations	uveal_tract	587	5	16828	48	CTNND2,MACF1,CPE,ADCY2,TRPM3
2.537e-02	-3.67	HNRNPL (heterogeneous nuclear ribonucleoprotein L)	protein interactions	3191	1958	10	19454	50	ABLIM1,TRPS1,NRG3,MACF1,BMPR1B,PARD3,MSI2,RPS6KA2,DTNA,DCLK2
2.541e-02	-3.67	CALB2 (calbindin 2)	protein interactions	794	10	1	19454	50	GPM6A
2.541e-02	-3.67	SERPINB11 (serpin family B member 11)	protein interactions	89778	10	1	19454	50	CPE
2.541e-02	-3.67	Smurf2 (SMAD specific E3 ubiquitin protein ligase 2)	protein interactions	66313	10	1	19454	50	GLIS3
2.541e-02	-3.67	Vbp1 (von Hippel-Lindau binding protein 1)	protein interactions	22327	10	1	19454	50	ABLIM1
2.541e-02	-3.67	SLC8A2 (solute carrier family 8 member A2)	protein interactions	6543	10	1	19454	50	GPM6A
2.541e-02	-3.67	P2rx7 (purinergic receptor P2X 7)	protein interactions	29665	10	1	19454	50	PTPRZ1
2.541e-02	-3.67	GSG1 (germ cell associated 1)	protein interactions	83445	10	1	19454	50	PITPNC1
2.548e-02	-3.67	protein tetramerization	biological process	GO:0051262	92	2	18204	49	AQP4,TRPM3
2.566e-02	-3.66	GS	smart domains	SM00467	7	1	9717	36	BMPR1B
2.566e-02	-3.66	PLEC	smart domains	SM00250	7	1	9717	36	MACF1
2.568e-02	-3.66	ATP hydrolysis activity	molecular function	GO:0016887	415	4	18094	49	CLU,ATP13A4,NAV3,ATP1A2
2.581e-02	-3.66	BTG3 (BTG anti-proliferation factor 3)	protein interactions	10950	97	2	19454	50	DCLK2,CLU
2.587e-02	-3.65	perineuronal net	cellular component	GO:0072534	10	1	19108	50	PTPRZ1
2.595e-02	-3.65	pancreas-other-adenoma	COSMIC cancer mutations	pancreas-other-adenoma	224	3	16828	48	BMPR1B,NAV3,CTNND2
2.599e-02	-3.65	enzyme-linked receptor protein signaling pathway	biological process	GO:0007167	626	5	18204	49	EFEMP1,NTRK2,SORBS1,BMPR1B,NRG3
2.599e-02	-3.65	regulation of extent of cell growth	biological process	GO:0061387	93	2	18204	49	NRCAM,MACF1
2.609e-02	-3.65	Lactose Degradation	SMPDB pathways	SMP0000457	12	1	1369	3	ATP1A2
2.609e-02	-3.65	Lactose Intolerance	SMPDB pathways	SMP0000458	12	1	1369	3	ATP1A2
2.616e-02	-3.64	protein localization to cell periphery	biological process	GO:1990778	238	3	18204	49	TNIK,MACF1,DPP10
2.625e-02	-3.64	NK-T_cell_lymphoma	COSMIC cancer mutations	NK-T_cell_lymphoma	225	3	16828	48	DTNA,MGAT4C,RFX4
2.630e-02	-3.64	Toll Like Receptor 5 (TLR5) Cascade	REACTOME pathways	R-HSA-168176	84	2	10285	31	MAPK10,RPS6KA2
2.630e-02	-3.64	MyD88 cascade initiated on plasma membrane	REACTOME pathways	R-HSA-975871	84	2	10285	31	RPS6KA2,MAPK10
2.630e-02	-3.64	Toll Like Receptor 10 (TLR10) Cascade	REACTOME pathways	R-HSA-168142	84	2	10285	31	MAPK10,RPS6KA2
2.631e-02	-3.64	FRAS1 (Fraser extracellular matrix complex subunit 1)	protein interactions	80144	98	2	19454	50	HPSE2,MGAT4C
2.631e-02	-3.64	DMD (dystrophin)	protein interactions	1756	98	2	19454	50	MAP3K5,DTNA
2.631e-02	-3.64	DNAAF2 (dynein axonemal assembly factor 2)	protein interactions	55172	98	2	19454	50	GPM6A,LSAMP
2.645e-02	-3.63	dermatan sulfate biosynthesis	BIOCYC pathways	HUMAN_PWY-6571	12	1	902	2	CSGALNACT1
2.647e-02	-3.63	soft_tissue-striated_muscle-rhabdomyosarcoma	COSMIC cancer mutations	soft_tissue-striated_muscle-rhabdomyosarcoma	594	5	16828	48	TRPS1,MACF1,CTNND2,SPON1,MAP3K5
2.649e-02	-3.63	EDTRNSPORT	prints domains	PR00173	7	1	5227	20	SLC1A2
2.649e-02	-3.63	HUDSXLRNA	prints domains	PR00961	7	1	5227	20	RBMS3
2.660e-02	-3.63	cellular response to cocaine	biological process	GO:0071314	10	1	18204	49	SLC1A2
2.660e-02	-3.63	cellular response to brain-derived neurotrophic factor stimulus	biological process	GO:1990416	10	1	18204	49	NTRK2
2.660e-02	-3.63	substrate-independent telencephalic tangential migration	biological process	GO:0021826	10	1	18204	49	NRG3
2.660e-02	-3.63	trans-synaptic signaling, modulating synaptic transmission	biological process	GO:0099550	10	1	18204	49	NTRK2
2.660e-02	-3.63	cAMP biosynthetic process	biological process	GO:0006171	10	1	18204	49	ADCY2
2.660e-02	-3.63	regulation of mesenchymal stem cell differentiation	biological process	GO:2000739	10	1	18204	49	SOX5
2.660e-02	-3.63	establishment of centrosome localization	biological process	GO:0051660	10	1	18204	49	PARD3
2.660e-02	-3.63	retinal rod cell development	biological process	GO:0046548	10	1	18204	49	NTRK2
2.660e-02	-3.63	substrate-independent telencephalic tangential interneuron migration	biological process	GO:0021843	10	1	18204	49	NRG3
2.666e-02	-3.62	Ig_sub2	interpro domains	IPR003598	239	3	18521	50	NTRK2,LSAMP,NRCAM
2.668e-02	-3.62	HCO3_transpt_euk	interpro domains	IPR003020	10	1	18521	50	SLC4A4
2.668e-02	-3.62	HCO3_transpt-like_TM_dom	interpro domains	IPR011531	10	1	18521	50	SLC4A4
2.668e-02	-3.62	MIP_CS	interpro domains	IPR022357	10	1	18521	50	AQP4
2.668e-02	-3.62	Doublecortin_dom_sf	interpro domains	IPR036572	10	1	18521	50	DCLK2
2.668e-02	-3.62	PAS_fold_3	interpro domains	IPR013655	10	1	18521	50	NPAS3
2.668e-02	-3.62	PTrfase/Anion_transptr	interpro domains	IPR016152	10	1	18521	50	SLC4A4
2.676e-02	-3.62	phosphatidylinositol transfer activity	molecular function	GO:0008526	10	1	18094	49	PITPNC1
2.676e-02	-3.62	neurotrophin binding	molecular function	GO:0043121	10	1	18094	49	NTRK2
2.676e-02	-3.62	polyamine transmembrane transporter activity	molecular function	GO:0015203	10	1	18094	49	ATP13A4
2.680e-02	-3.62	ZFHX3 (zinc finger homeobox 3)	protein interactions	463	99	2	19454	50	TRPS1,SOX5
2.681e-02	-3.62	Terminal pathway of complement	REACTOME pathways	R-HSA-166665	9	1	10285	31	CLU
2.688e-02	-3.62	Diseases of glycosylation	REACTOME pathways	R-HSA-3781865	85	2	10285	31	SPON1,GPC5
2.693e-02	-3.61	NCK2 (NCK adaptor protein 2)	protein interactions	8440	252	3	19454	50	NTRK2,SORBS1,TNIK
2.697e-02	-3.61	Transmission across Chemical Synapses	REACTOME pathways	R-HSA-112315	217	3	10285	31	ADCY2,RPS6KA2,SLC1A2
2.702e-02	-3.61	cell motility	biological process	GO:0048870	1101	7	18204	49	NTRK2,GPM6A,FMN2,NRCAM,CTNNA2,NRG3,GPC5
2.704e-02	-3.61	Doublecortin domain	gene3d domains	3.10.20.230	9	1	14470	44	DCLK2
2.711e-02	-3.61	Thyroid hormone synthesis	KEGG pathways	hsa04918	74	2	7161	25	ATP1A2,ADCY2
2.711e-02	-3.61	Thyroid hormone synthesis	KEGG pathways	ko04918	74	2	7161	25	ADCY2,ATP1A2
2.720e-02	-3.60	HCO3_cotransp	pfam domains	PF00955	10	1	17795	49	SLC4A4
2.720e-02	-3.60	PAS_3	pfam domains	PF08447	10	1	17795	49	NPAS3
2.721e-02	-3.60	PRKAA1 (protein kinase AMP-activated catalytic subunit alpha 1)	protein interactions	5562	253	3	19454	50	SLC4A4,RPS6KA2,CPE
2.725e-02	-3.60	GATA_ZN_FINGER_1	prosite domains	PS00344	8	1	12186	42	TRPS1
2.725e-02	-3.60	HP	prosite domains	PS51089	8	1	12186	42	ABLIM1
2.731e-02	-3.60	ATP4A (ATPase H+/K+ transporting subunit alpha)	protein interactions	495	100	2	19454	50	GPM6A,ATP1A2
2.731e-02	-3.60	EDEM2 (ER degradation enhancing alpha-mannosidase like protein 2)	protein interactions	55741	100	2	19454	50	HPSE2,CLU
2.758e-02	-3.59	monoatomic cation transmembrane transport	biological process	GO:0098655	636	5	18204	49	ATP1A2,TRPM3,ATP13A4,SLC4A4,GPM6A
2.779e-02	-3.58	Gastric acid secretion	KEGG pathways	ko04971	75	2	7161	25	ATP1A2,ADCY2
2.779e-02	-3.58	Gastric acid secretion	KEGG pathways	hsa04971	75	2	7161	25	ATP1A2,ADCY2
2.780e-02	-3.58	cell surface receptor protein tyrosine kinase signaling pathway	biological process	GO:0007169	428	4	18204	49	NTRK2,EFEMP1,SORBS1,NRG3
2.783e-02	-3.58	NGF signalling via TRKA from the plasma membrane	REACTOME pathways	R-HSA-187037	387	4	10285	31	RPS6KA2,NRG3,NTRK2,ADCY2
2.787e-02	-3.58	ATPase-coupled transmembrane transporter activity	molecular function	GO:0042626	96	2	18094	49	ATP13A4,ATP1A2
2.788e-02	-3.58	regulation of neuron apoptotic process	biological process	GO:0043523	244	3	18204	49	PTPRZ1,NTRK2,CLU
2.792e-02	-3.58	Wipi2 (WD repeat domain, phosphoinositide interacting 2)	protein interactions	74781	11	1	19454	50	MACF1
2.792e-02	-3.58	AQP5 (aquaporin 5)	protein interactions	362	11	1	19454	50	ATP1A2
2.792e-02	-3.58	Cobll1 (Cobl-like 1)	protein interactions	319876	11	1	19454	50	ABLIM1
2.792e-02	-3.58	Batf3 (basic leucine zipper transcription factor, ATF-like 3)	protein interactions	381319	11	1	19454	50	MACF1
2.792e-02	-3.58	NTS (neurotensin)	protein interactions	4922	11	1	19454	50	CPE
2.792e-02	-3.58	SYN3 (synapsin III)	protein interactions	8224	11	1	19454	50	GPM6A
2.792e-02	-3.58	ADCY5 (adenylate cyclase 5)	protein interactions	111	11	1	19454	50	ADCY2
2.792e-02	-3.58	MSRB1 (methionine sulfoxide reductase B1)	protein interactions	51734	11	1	19454	50	CLU
2.810e-02	-3.57	positive regulation of JNK cascade	biological process	GO:0046330	97	2	18204	49	TNIK,MAP3K5
2.814e-02	-3.57	PROKAR_LIPOPROTEIN	prosite domains	PS51257	76	2	12186	42	CPE,GLIS3
2.822e-02	-3.57	extrinsic component of plasma membrane	cellular component	GO:0019897	100	2	19108	50	DTNA,CTNNA2
2.824e-02	-3.57	Trehalose Degradation	SMPDB pathways	SMP0000467	13	1	1369	3	ATP1A2
2.826e-02	-3.57	LIM	smart domains	SM00132	71	2	9717	36	NEBL,ABLIM1
2.832e-02	-3.56	human chr8q12.3	chromosome location	human chr8q12.3	15	1	26134	50	NKAIN3
2.832e-02	-3.56	human chr10p12.31	chromosome location	human chr10p12.31	15	1	26134	50	NEBL
2.832e-02	-3.56	human chr12q21.2	chromosome location	human chr12q21.2	15	1	26134	50	NAV3
2.832e-02	-3.56	KRTAP6-1 (keratin associated protein 6-1)	protein interactions	337966	102	2	19454	50	EFEMP1,GLIS3
2.832e-02	-3.56	TMPRSS13 (transmembrane serine protease 13)	protein interactions	84000	102	2	19454	50	SPON1,CPE
2.842e-02	-3.56	perisynaptic extracellular matrix	cellular component	GO:0098966	11	1	19108	50	PTPRZ1
2.842e-02	-3.56	trans-synaptic signaling	biological process	GO:0099537	431	4	18204	49	SLC1A2,RPS6KA2,NTRK2,DTNA
2.847e-02	-3.56	positive regulation of neurogenesis	biological process	GO:0050769	246	3	18204	49	MACF1,NTRK2,PTPRZ1
2.853e-02	-3.56	eye	COSMIC cancer mutations	eye	606	5	16828	48	MACF1,CTNND2,CPE,ADCY2,TRPM3
2.884e-02	-3.55	ZDHHC5 (zinc finger DHHC-type palmitoyltransferase 5)	protein interactions	25921	103	2	19454	50	NTRK2,PARD3
2.884e-02	-3.55	RAB6B (RAB6B, member RAS oncogene family)	protein interactions	51560	103	2	19454	50	BMPR1B,GPM6A
2.884e-02	-3.55	CSGALNACT2 (chondroitin sulfate N-acetylgalactosaminyltransferase 2)	protein interactions	55454	103	2	19454	50	MGAT4C,CSGALNACT1
2.891e-02	-3.54	transmembrane transporter activity	molecular function	GO:0022857	1110	7	18094	49	AQP4,TRPM3,ATP13A4,SLC1A2,GPM6A,SLC4A4,ATP1A2
2.917e-02	-3.53	bone morphogenesis	biological process	GO:0060349	99	2	18204	49	BMPR1B,CSGALNACT1
2.920e-02	-3.53	FGFR4 (fibroblast growth factor receptor 4)	protein interactions	2264	455	4	19454	50	SORBS1,MAP3K5,TNIK,ABLIM1
2.922e-02	-3.53	establishment or maintenance of transmembrane electrochemical gradient	biological process	GO:0010248	11	1	18204	49	ATP1A2
2.922e-02	-3.53	antral ovarian follicle growth	biological process	GO:0001547	11	1	18204	49	BMPR1B
2.922e-02	-3.53	heparin biosynthetic process	biological process	GO:0030210	11	1	18204	49	CSGALNACT1
2.922e-02	-3.53	ectodermal placode formation	biological process	GO:0060788	11	1	18204	49	NRG3
2.922e-02	-3.53	ectodermal placode morphogenesis	biological process	GO:0071697	11	1	18204	49	NRG3
2.922e-02	-3.53	polyamine transport	biological process	GO:0015846	11	1	18204	49	ATP13A4
2.922e-02	-3.53	lactone metabolic process	biological process	GO:1901334	11	1	18204	49	ATP1A2
2.922e-02	-3.53	L-glutamate import across plasma membrane	biological process	GO:0098712	11	1	18204	49	SLC1A2
2.922e-02	-3.53	endothelial cell apoptotic process	biological process	GO:0072577	11	1	18204	49	MAP3K5
2.922e-02	-3.53	pyramidal neuron development	biological process	GO:0021860	11	1	18204	49	DCLK2
2.922e-02	-3.53	glutamate secretion	biological process	GO:0014047	11	1	18204	49	NTRK2
2.922e-02	-3.53	negative regulation of neuron migration	biological process	GO:2001223	11	1	18204	49	NRG3
2.922e-02	-3.53	L-ascorbic acid metabolic process	biological process	GO:0019852	11	1	18204	49	ATP1A2
2.922e-02	-3.53	L-aspartate transmembrane transport	biological process	GO:0070778	11	1	18204	49	SLC1A2
2.927e-02	-3.53	VHP	smart domains	SM00153	8	1	9717	36	ABLIM1
2.927e-02	-3.53	blood vessel morphogenesis	biological process	GO:0048514	435	4	18204	49	RORA,NRCAM,HIF3A,NTRK2
2.931e-02	-3.53	Tyr_kinase_rcpt_2_CS	interpro domains	IPR002011	11	1	18521	50	NTRK2
2.934e-02	-3.53	nervous system process	biological process	GO:0050877	1376	8	18204	49	EFEMP1,PTPRZ1,AQP4,ABLIM1,NTRK2,NRCAM,CTNNA2,ATP1A2
2.940e-02	-3.53	JUN kinase kinase kinase activity	molecular function	GO:0004706	11	1	18094	49	MAP3K5
2.940e-02	-3.53	sulfur amino acid transmembrane transporter activity	molecular function	GO:0000099	11	1	18094	49	SLC1A2
2.972e-02	-3.52	EGF_3	prosite domains	PS50026	196	3	12186	42	PAMR1,EFEMP1,NRG3
2.975e-02	-3.51	Adenylate cyclase activating pathway	REACTOME pathways	R-HSA-170660	10	1	10285	31	ADCY2
2.975e-02	-3.51	Bicarbonate transporters	REACTOME pathways	R-HSA-425381	10	1	10285	31	SLC4A4
2.975e-02	-3.51	PI3K events in ERBB4 signaling	REACTOME pathways	R-HSA-1250342	10	1	10285	31	NRG3
2.975e-02	-3.51	Activation of the AP-1 family of transcription factors	REACTOME pathways	R-HSA-450341	10	1	10285	31	MAPK10
2.988e-02	-3.51	BEND3 (BEN domain containing 3)	protein interactions	57673	105	2	19454	50	TRPS1,TNIK
2.988e-02	-3.51	PAS_11	pfam domains	PF14598	11	1	17795	49	HIF3A
3.000e-02	-3.51	Helical hairpin bin	gene3d domains	1.10.287.570	10	1	14470	44	SLC4A4
3.010e-02	-3.50	SH3 Domains	gene3d domains	2.30.30.40	223	3	14470	44	MACF1,SORBS1,NEBL
3.022e-02	-3.50	GATAZNFINGER	prints domains	PR00619	8	1	5227	20	TRPS1
3.027e-02	-3.50	regulation of glucose metabolic process	biological process	GO:0010906	101	2	18204	49	RORA,SORBS1
3.033e-02	-3.50	skin-arm-malignant_melanoma	COSMIC cancer mutations	skin-arm-malignant_melanoma	1308	8	16828	48	TRPS1,TRPM3,DPP10,SLC4A4,NPAS3,MACF1,SORBS1,ATP1A2
3.040e-02	-3.49	USP6NL (USP6 N-terminal like)	protein interactions	9712	106	2	19454	50	NTRK2,PARD3
3.042e-02	-3.49	ART4 (ADP-ribosyltransferase 4 (inactive) (Dombrock blood group))	protein interactions	420	12	1	19454	50	GPM6A
3.042e-02	-3.49	BAMBI (BMP and activin membrane bound inhibitor)	protein interactions	25805	12	1	19454	50	BMPR1B
3.042e-02	-3.49	PROK2 (prokineticin 2)	protein interactions	60675	12	1	19454	50	CPE
3.042e-02	-3.49	KIF26A (kinesin family member 26A)	protein interactions	26153	12	1	19454	50	MAPK10
3.042e-02	-3.49	CA4 (carbonic anhydrase 4)	protein interactions	762	12	1	19454	50	SLC4A4
3.042e-02	-3.49	LMP-1 (latent membrane protein LMP-1)	protein interactions	3783750	12	1	19454	50	TNIK
3.042e-02	-3.49	MMP25 (matrix metallopeptidase 25)	protein interactions	64386	12	1	19454	50	CLU
3.042e-02	-3.49	TREM2 (triggering receptor expressed on myeloid cells 2)	protein interactions	54209	12	1	19454	50	CLU
3.042e-02	-3.49	CDHR2 (cadherin related family member 2)	protein interactions	54825	12	1	19454	50	RPS6KA2
3.042e-02	-3.49	NTF4 (neurotrophin 4)	protein interactions	4909	12	1	19454	50	NTRK2
3.042e-02	-3.49	Pard6b (par-6 family cell polarity regulator beta)	protein interactions	58220	12	1	19454	50	PARD3
3.042e-02	-3.49	NPY4R (neuropeptide Y receptor Y4)	protein interactions	5540	12	1	19454	50	MAP3K5
3.049e-02	-3.49	TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation	REACTOME pathways	R-HSA-975138	91	2	10285	31	RPS6KA2,MAPK10
3.054e-02	-3.49	oesophagus-carcinoma-adenocarcinoma	COSMIC cancer mutations	oesophagus-carcinoma-adenocarcinoma	13112	43	16828	48	TNIK,NPAS3,HPSE2,RFX4,FMN2,CSGALNACT1,MGAT4C,CTNND2,CLU,DPP10,MACF1,ATP1A2,ATP13A4,ADCY2,SOX5,CPE,GPM6A,SPON1,BMPR1B,NEBL,PTPRZ1,SLC4A4,LSAMP,SORBS1,DCLK2,NRG3,RORA,GLIS3,PAMR1,SLC1A2,NAV3,NKAIN3,RPS6KA2,TRPS1,GPC5,NRCAM,TRPM3,PARD3,EFEMP1,NTRK2,AQP4,HIF3A,MAP3K5
3.058e-02	-3.49	CTNNB1 (catenin beta 1)	protein interactions	1499	926	6	19454	50	PARD3,DTNA,PTPRZ1,CTNND2,CTNNA2,SORBS1
3.060e-02	-3.49	DC	prosite domains	PS50309	9	1	12186	42	DCLK2
3.060e-02	-3.49	RFX_DBD	prosite domains	PS51526	9	1	12186	42	RFX4
3.061e-02	-3.49	cAMP signaling pathway	KEGG pathways	ko04024	198	3	7161	25	ATP1A2,ADCY2,MAPK10
3.061e-02	-3.49	cAMP signaling pathway	KEGG pathways	hsa04024	198	3	7161	25	MAPK10,ATP1A2,ADCY2
3.093e-02	-3.48	EFR3A (EFR3 homolog A)	protein interactions	23167	107	2	19454	50	PARD3,RPS6KA2
3.096e-02	-3.48	sodium:potassium-exchanging ATPase complex	cellular component	GO:0005890	12	1	19108	50	ATP1A2
3.096e-02	-3.48	synapse-associated extracellular matrix	cellular component	GO:0099535	12	1	19108	50	PTPRZ1
3.100e-02	-3.47	Heparan sulfate degradation	KEGG pathways	M00078	9	1	7161	25	HPSE2
3.100e-02	-3.47	Heparan sulfate degradation	KEGG pathways	hsa_M00078	9	1	7161	25	HPSE2
3.114e-02	-3.47	Laminin	gene3d domains	2.10.25.10	226	3	14470	44	NRG3,PAMR1,EFEMP1
3.118e-02	-3.47	bone-femur-chondrosarcoma	COSMIC cancer mutations	bone-femur-chondrosarcoma	419	4	16828	48	HPSE2,ADCY2,SPON1,SLC4A4
3.147e-02	-3.46	CLASP1 (cytoplasmic linker associated protein 1)	protein interactions	23332	108	2	19454	50	DCLK2,MACF1
3.147e-02	-3.46	BIN1 (bridging integrator 1)	protein interactions	274	108	2	19454	50	CLU,GPM6A
3.151e-02	-3.46	VCL (vinculin)	protein interactions	7414	268	3	19454	50	MACF1,NEBL,SORBS1
3.151e-02	-3.46	protein complex oligomerization	biological process	GO:0051259	256	3	18204	49	TRPM3,AQP4,SLC1A2
3.165e-02	-3.45	CH	prosite domains	PS50021	81	2	12186	42	NAV3,MACF1
3.174e-02	-3.45	Toll Like Receptor 7/8 (TLR7/8) Cascade	REACTOME pathways	R-HSA-168181	93	2	10285	31	MAPK10,RPS6KA2
3.174e-02	-3.45	MyD88 dependent cascade initiated on endosome	REACTOME pathways	R-HSA-975155	93	2	10285	31	RPS6KA2,MAPK10
3.182e-02	-3.45	ear	COSMIC cancer mutations	ear	624	5	16828	48	MAP3K5,MGAT4C,NPAS3,DPP10,RPS6KA2
3.183e-02	-3.45	active transmembrane transporter activity	molecular function	GO:0022804	444	4	18094	49	ATP1A2,SLC4A4,ATP13A4,SLC1A2
3.184e-02	-3.45	neuronal ion channel clustering	biological process	GO:0045161	12	1	18204	49	NRCAM
3.184e-02	-3.45	mammalian oogenesis stage	biological process	GO:0022605	12	1	18204	49	BMPR1B
3.184e-02	-3.45	sulfur amino acid transport	biological process	GO:0000101	12	1	18204	49	SLC1A2
3.184e-02	-3.45	dermatan sulfate proteoglycan metabolic process	biological process	GO:0050655	12	1	18204	49	CSGALNACT1
3.184e-02	-3.45	positive regulation of extrinsic apoptotic signaling pathway via death domain receptors	biological process	GO:1902043	12	1	18204	49	BMPR1B
3.185e-02	-3.45	embryonal	COSMIC cancer mutations	embryonal	2659	13	16828	48	NPAS3,PTPRZ1,FMN2,GLIS3,RORA,SORBS1,TRPM3,CTNND2,SPON1,MAP3K5,ADCY2,AQP4,MACF1
3.185e-02	-3.45	soft_tissue-striated_muscle-rhabdomyosarcoma-embryonal	COSMIC cancer mutations	soft_tissue-striated_muscle-rhabdomyosarcoma-embryonal	2659	13	16828	48	SORBS1,FMN2,RORA,GLIS3,PTPRZ1,NPAS3,AQP4,MACF1,MAP3K5,ADCY2,SPON1,CTNND2,TRPM3
3.193e-02	-3.44	MAP_kinase_CS	interpro domains	IPR003527	12	1	18521	50	MAPK10
3.193e-02	-3.44	TGFB_receptor	interpro domains	IPR000333	12	1	18521	50	BMPR1B
3.200e-02	-3.44	PRR20A (proline rich 20A)	protein interactions	122183	109	2	19454	50	TRPM3,SOX5
3.203e-02	-3.44	protein binding involved in heterotypic cell-cell adhesion	molecular function	GO:0086080	12	1	18094	49	NRCAM
3.203e-02	-3.44	adenylate cyclase binding	molecular function	GO:0008179	12	1	18094	49	ADCY2
3.203e-02	-3.44	dipeptidyl-peptidase activity	molecular function	GO:0008239	12	1	18094	49	DPP10
3.204e-02	-3.44	human chr9q21.33	chromosome location	human chr9q21.33	17	1	26134	50	NTRK2
3.211e-02	-3.44	WDR6 (WD repeat domain 6)	protein interactions	11180	270	3	19454	50	NTRK2,RPS6KA2,PARD3
3.230e-02	-3.43	exopeptidase activity	molecular function	GO:0008238	104	2	18094	49	DPP10,CPE
3.246e-02	-3.43	urinary_tract-bladder-carcinoma	COSMIC cancer mutations	urinary_tract-bladder-carcinoma	14050	45	16828	48	HPSE2,CSGALNACT1,TNIK,NPAS3,ATP1A2,SPON1,GPM6A,ATP13A4,ADCY2,NRG3,DCLK2,PAMR1,RORA,SLC4A4,BMPR1B,HIF3A,MSI2,DTNA,TRPS1,GPC5,NAV3,NTRK2,EFEMP1,PARD3,TRPM3,MGAT4C,RFX4,FMN2,PITPNC1,MACF1,CPE,SOX5,CLU,CTNND2,DPP10,LSAMP,SORBS1,GLIS3,PTPRZ1,NEBL,MAP3K5,ABLIM1,RPS6KA2,SLC1A2,NRCAM
3.251e-02	-3.43	neural precursor cell proliferation	biological process	GO:0061351	105	2	18204	49	SOX5,RORA
3.251e-02	-3.43	positive regulation of protein localization to membrane	biological process	GO:1905477	105	2	18204	49	SORBS1,DPP10
3.256e-02	-3.42	SNCA (synuclein alpha)	protein interactions	6622	696	5	19454	50	TNIK,GPM6A,NTRK2,MACF1,CLU
3.256e-02	-3.42	CarboxypepD_reg	pfam domains	PF13620	12	1	17795	49	CPE
3.287e-02	-3.42	DCX	smart domains	SM00537	9	1	9717	36	DCLK2
3.291e-02	-3.41	JAM2 (junctional adhesion molecule 2)	protein interactions	58494	13	1	19454	50	PARD3
3.291e-02	-3.41	RAB3C (RAB3C, member RAS oncogene family)	protein interactions	115827	13	1	19454	50	GPM6A
3.291e-02	-3.41	SPINK5 (serine peptidase inhibitor Kazal type 5)	protein interactions	11005	13	1	19454	50	CSGALNACT1
3.291e-02	-3.41	PCAT1 (prostate cancer associated transcript 1)	protein interactions	100750225	13	1	19454	50	NAV3
3.291e-02	-3.41	DDIAS (DNA damage induced apoptosis suppressor)	protein interactions	220042	13	1	19454	50	EFEMP1
3.296e-02	-3.41	Carboxypeptidase-like, regulatory domain	gene3d domains	2.60.40.1120	11	1	14470	44	CPE
3.300e-02	-3.41	Toll Like Receptor TLR1:TLR2 Cascade	REACTOME pathways	R-HSA-168179	95	2	10285	31	MAPK10,RPS6KA2
3.300e-02	-3.41	MyD88:Mal cascade initiated on plasma membrane	REACTOME pathways	R-HSA-166058	95	2	10285	31	MAPK10,RPS6KA2
3.300e-02	-3.41	Toll Like Receptor TLR6:TLR2 Cascade	REACTOME pathways	R-HSA-168188	95	2	10285	31	RPS6KA2,MAPK10
3.300e-02	-3.41	Toll Like Receptor 2 (TLR2) Cascade	REACTOME pathways	R-HSA-181438	95	2	10285	31	RPS6KA2,MAPK10
3.300e-02	-3.41	dermatan sulfate biosynthesis	BIOCYC pathways	META_PWY-6571	15	1	902	2	CSGALNACT1
3.307e-02	-3.41	oogenesis	biological process	GO:0048477	106	2	18204	49	FMN2,BMPR1B
3.319e-02	-3.41	arm	COSMIC cancer mutations	arm	1331	8	16828	48	SORBS1,MACF1,ATP1A2,TRPM3,SLC4A4,NPAS3,DPP10,TRPS1
3.363e-02	-3.39	EDA (ectodysplasin A)	protein interactions	1896	112	2	19454	50	RPS6KA2,GPM6A
3.363e-02	-3.39	CEP170P1 (centrosomal protein 170 pseudogene 1)	protein interactions	645455	112	2	19454	50	MACF1,TRPS1
3.363e-02	-3.39	MPP1 (MAGUK p55 scaffold protein 1)	protein interactions	4354	112	2	19454	50	TRPS1,RPS6KA2
3.363e-02	-3.39	TBR1 (T-box brain transcription factor 1)	protein interactions	10716	112	2	19454	50	SOX5,TRPS1
3.363e-02	-3.39	TSC22D4 (TSC22 domain family member 4)	protein interactions	81628	112	2	19454	50	CLU,ABLIM1
3.374e-02	-3.39	skin-scalp-malignant_melanoma	COSMIC cancer mutations	skin-scalp-malignant_melanoma	634	5	16828	48	NEBL,PTPRZ1,FMN2,RPS6KA2,SORBS1
3.388e-02	-3.38	regulation of developmental process	biological process	GO:0050793	2540	12	18204	49	NTRK2,MAP3K5,NRCAM,BMPR1B,RORA,SOX5,PARD3,PTPRZ1,EFEMP1,MACF1,TRPS1,TNIK
3.389e-02	-3.38	human chr7q31.32	chromosome location	human chr7q31.32	18	1	26134	50	PTPRZ1
3.394e-02	-3.38	CDK4 (cyclin dependent kinase 4)	protein interactions	1019	276	3	19454	50	BMPR1B,MAP3K5,SORBS1
3.395e-02	-3.38	MIP	prosite domains	PS00221	10	1	12186	42	AQP4
3.396e-02	-3.38	regulation of nervous system development	biological process	GO:0051960	456	4	18204	49	PARD3,MACF1,PTPRZ1,NTRK2
3.402e-02	-3.38	steroid binding	molecular function	GO:0005496	107	2	18094	49	RORA,ATP1A2
3.418e-02	-3.38	GFI1B (growth factor independent 1B transcriptional repressor)	protein interactions	8328	113	2	19454	50	DTNA,EFEMP1
3.418e-02	-3.38	KIRREL1 (kirre like nephrin family adhesion molecule 1)	protein interactions	55243	113	2	19454	50	RPS6KA2,PARD3
3.428e-02	-3.37	Toll Like Receptor 9 (TLR9) Cascade	REACTOME pathways	R-HSA-168138	97	2	10285	31	RPS6KA2,MAPK10
3.439e-02	-3.37	regulation of canonical Wnt signaling pathway	biological process	GO:0060828	265	3	18204	49	CTNND2,RBMS3,GPC5
3.444e-02	-3.37	defense response to tumor cell	biological process	GO:0002357	13	1	18204	49	RBMS3
3.444e-02	-3.37	prepulse inhibition	biological process	GO:0060134	13	1	18204	49	CTNNA2
3.444e-02	-3.37	negative regulation of amyloid fibril formation	biological process	GO:1905907	13	1	18204	49	CLU
3.444e-02	-3.37	ectodermal placode development	biological process	GO:0071696	13	1	18204	49	NRG3
3.444e-02	-3.37	regulation of respiratory gaseous exchange by nervous system process	biological process	GO:0002087	13	1	18204	49	ATP1A2
3.444e-02	-3.37	negative regulation of cytosolic calcium ion concentration	biological process	GO:0051481	13	1	18204	49	ATP1A2
3.444e-02	-3.37	cerebellar Purkinje cell differentiation	biological process	GO:0021702	13	1	18204	49	RORA
3.444e-02	-3.37	T-helper 17 cell differentiation	biological process	GO:0072539	13	1	18204	49	RORA
3.457e-02	-3.36	TJP2 (tight junction protein 2)	protein interactions	9414	278	3	19454	50	NEBL,SORBS1,PARD3
3.462e-02	-3.36	positive regulation of multicellular organismal process	biological process	GO:0051240	1691	9	18204	49	NTRK2,SOX5,ATP1A2,PARD3,BMPR1B,PTPRZ1,CLU,RORA,MACF1
3.465e-02	-3.36	transforming growth factor beta receptor activity	molecular function	GO:0005024	13	1	18094	49	BMPR1B
3.465e-02	-3.36	potassium ion binding	molecular function	GO:0030955	13	1	18094	49	ATP1A2
3.465e-02	-3.36	monoatomic cation:bicarbonate symporter activity	molecular function	GO:0140410	13	1	18094	49	SLC4A4
3.466e-02	-3.36	synaptic signaling	biological process	GO:0099536	459	4	18204	49	NTRK2,RPS6KA2,SLC1A2,DTNA
3.474e-02	-3.36	TNFSF13B (TNF superfamily member 13b)	protein interactions	10673	114	2	19454	50	CLU,MAP3K5
3.481e-02	-3.36	regulation of protein localization to plasma membrane	biological process	GO:1903076	109	2	18204	49	DPP10,SORBS1
3.501e-02	-3.35	ErbB signaling pathway	KEGG pathways	hsa04012	85	2	7161	25	MAPK10,NRG3
3.501e-02	-3.35	ErbB signaling pathway	KEGG pathways	ko04012	85	2	7161	25	NRG3,MAPK10
3.501e-02	-3.35	Insulin secretion	KEGG pathways	hsa04911	85	2	7161	25	ATP1A2,ADCY2
3.518e-02	-3.35	chondroitin sulfate biosynthesis	BIOCYC pathways	HUMAN_PWY-6569	16	1	902	2	CSGALNACT1
3.527e-02	-3.34	ACTB (actin beta)	protein interactions	60	958	6	19454	50	DTNA,NEBL,FMN2,MACF1,SORBS1,ABLIM1
3.530e-02	-3.34	CDH2 (cadherin 2)	protein interactions	1000	115	2	19454	50	PARD3,CTNND2
3.530e-02	-3.34	DTNA (dystrobrevin alpha)	protein interactions	1837	115	2	19454	50	PARD3,NTRK2
3.540e-02	-3.34	Stag2 (STAG2 cohesin complex component)	protein interactions	20843	14	1	19454	50	CLU
3.540e-02	-3.34	Nedd4 (neural precursor cell expressed, developmentally down-regulated 4)	protein interactions	17999	14	1	19454	50	GLIS3
3.540e-02	-3.34	ZNF628 (zinc finger protein 628)	protein interactions	89887	14	1	19454	50	EFEMP1
3.540e-02	-3.34	C9 (complement C9)	protein interactions	735	14	1	19454	50	CLU
3.540e-02	-3.34	Aifm1 (apoptosis-inducing factor, mitochondrion-associated 1)	protein interactions	26926	14	1	19454	50	CLU
3.540e-02	-3.34	SLC1A2 (solute carrier family 1 member 2)	protein interactions	6506	14	1	19454	50	SLC1A2
3.540e-02	-3.34	Asap1 (ArfGAP with SH3 domain, ankyrin repeat and PH domain1)	protein interactions	13196	14	1	19454	50	MACF1
3.540e-02	-3.34	BOD1L2 (biorientation of chromosomes in cell division 1 like 2)	protein interactions	284257	14	1	19454	50	FMN2
3.540e-02	-3.34	RHEBL1 (RHEB like 1)	protein interactions	121268	14	1	19454	50	BMPR1B
3.559e-02	-3.34	Toll Like Receptor 3 (TLR3) Cascade	REACTOME pathways	R-HSA-168164	99	2	10285	31	RPS6KA2,MAPK10
3.559e-02	-3.34	TRIF-mediated TLR3/TLR4 signaling	REACTOME pathways	R-HSA-937061	99	2	10285	31	MAPK10,RPS6KA2
3.559e-02	-3.34	MyD88-independent TLR3/TLR4 cascade	REACTOME pathways	R-HSA-166166	99	2	10285	31	MAPK10,RPS6KA2
3.559e-02	-3.34	Defective EXT2 causes exostoses 2	REACTOME pathways	R-HSA-3656237	12	1	10285	31	GPC5
3.559e-02	-3.34	Regulation of gene expression by Hypoxia-inducible Factor	REACTOME pathways	R-HSA-1234158	12	1	10285	31	HIF3A
3.559e-02	-3.34	Defective EXT1 causes exostoses 1, TRPS2 and CHDS	REACTOME pathways	R-HSA-3656253	12	1	10285	31	GPC5
3.561e-02	-3.34	regulation of membrane potential	biological process	GO:0042391	463	4	18204	49	ATP1A2,NRCAM,SLC4A4,NTRK2
3.574e-02	-3.33	human chr5p15.2	chromosome location	human chr5p15.2	19	1	26134	50	CTNND2
3.585e-02	-3.33	cellular response to organic cyclic compound	biological process	GO:0071407	464	4	18204	49	RORA,ATP1A2,ADCY2,SLC1A2
3.586e-02	-3.33	RBBP8 (RB binding protein 8, endonuclease)	protein interactions	5932	116	2	19454	50	CTNNA2,CLU
3.589e-02	-3.33	plasma membrane raft	cellular component	GO:0044853	114	2	19108	50	ATP1A2,SORBS1
3.590e-02	-3.33	Alpha-catenin/vinculin-like	gene3d domains	1.20.120.230	12	1	14470	44	CTNNA2
3.603e-02	-3.32	chromaffin granule	cellular component	GO:0042583	14	1	19108	50	CLU
3.627e-02	-3.32	skin-extremity-malignant_melanoma	COSMIC cancer mutations	skin-extremity-malignant_melanoma	1875	10	16828	48	NTRK2,PARD3,PTPRZ1,PITPNC1,NEBL,NAV3,FMN2,ADCY2,ATP13A4,HPSE2
3.638e-02	-3.31	extremity	COSMIC cancer mutations	extremity	1876	10	16828	48	ADCY2,ATP13A4,FMN2,HPSE2,NTRK2,PITPNC1,NEBL,PARD3,PTPRZ1,NAV3
3.642e-02	-3.31	ZMYND19 (zinc finger MYND-type containing 19)	protein interactions	116225	117	2	19454	50	SPON1,CTNND2
3.647e-02	-3.31	HYOU1 (hypoxia up-regulated 1)	protein interactions	10525	284	3	19454	50	CLU,CPE,EFEMP1
3.647e-02	-3.31	LATS2 (large tumor suppressor kinase 2)	protein interactions	26524	284	3	19454	50	SORBS1,MAP3K5,PARD3
3.670e-02	-3.31	EGF_2	prosite domains	PS01186	213	3	12186	42	EFEMP1,NRG3,PAMR1
3.675e-02	-3.30	superficial_spreading	COSMIC cancer mutations	superficial_spreading	1110	7	16828	48	ATP13A4,ADCY2,MGAT4C,SORBS1,MACF1,SLC4A4,CTNND2
3.676e-02	-3.30	heterocyclic compound binding	molecular function	GO:1901363	2263	11	18094	49	BMPR1B,DCLK2,NAV3,MAP3K5,ATP13A4,RPS6KA2,ATP1A2,TNIK,MAPK10,NTRK2,ADCY2
3.678e-02	-3.30	bHLH_dom	interpro domains	IPR011598	112	2	18521	50	HIF3A,NPAS3
3.678e-02	-3.30	HLH_DNA-bd_sf	interpro domains	IPR036638	112	2	18521	50	HIF3A,NPAS3
3.691e-02	-3.30	L1CAM interactions	REACTOME pathways	R-HSA-373760	101	2	10285	31	NRCAM,RPS6KA2
3.699e-02	-3.30	CEACAM8 (CEA cell adhesion molecule 8)	protein interactions	1088	118	2	19454	50	CPE,CLU
3.704e-02	-3.30	cell surface receptor signaling pathway	biological process	GO:0007166	1992	10	18204	49	NTRK2,NRG3,BMPR1B,SORBS1,EFEMP1,MAPK10,TNIK,CTNND2,MACF1,CPE
3.704e-02	-3.30	response to forskolin	biological process	GO:1904321	14	1	18204	49	ADCY2
3.704e-02	-3.30	cerebrospinal fluid circulation	biological process	GO:0090660	14	1	18204	49	AQP4
3.704e-02	-3.30	glutathione biosynthetic process	biological process	GO:0006750	14	1	18204	49	SLC1A2
3.704e-02	-3.30	cellular response to forskolin	biological process	GO:1904322	14	1	18204	49	ADCY2
3.704e-02	-3.30	relaxation of cardiac muscle	biological process	GO:0055119	14	1	18204	49	ATP1A2
3.704e-02	-3.30	negative regulation of sodium ion transmembrane transporter activity	biological process	GO:2000650	14	1	18204	49	ATP1A2
3.706e-02	-3.30	vascular process in circulatory system	biological process	GO:0003018	273	3	18204	49	ATP1A2,SLC1A2,SLC4A4
3.715e-02	-3.29	Aquaporin-like	interpro domains	IPR023271	14	1	18521	50	AQP4
3.715e-02	-3.29	MIP	interpro domains	IPR000425	14	1	18521	50	AQP4
3.717e-02	-3.29	dendrite development	biological process	GO:0016358	113	2	18204	49	CTNND2,CTNNA2
3.727e-02	-3.29	L-glutamate transmembrane transporter activity	molecular function	GO:0005313	14	1	18094	49	SLC1A2
3.727e-02	-3.29	microtubule minus-end binding	molecular function	GO:0051011	14	1	18094	49	MACF1
3.728e-02	-3.29	RECEPTOR_TYR_KIN_II	prosite domains	PS00239	11	1	12186	42	NTRK2
3.728e-02	-3.29	GATA_ZN_FINGER_2	prosite domains	PS50114	11	1	12186	42	TRPS1
3.735e-02	-3.29	bladder	COSMIC cancer mutations	bladder	14112	45	16828	48	PITPNC1,MGAT4C,RFX4,FMN2,DPP10,CTNND2,CLU,CPE,SOX5,MACF1,NEBL,PTPRZ1,GLIS3,SORBS1,LSAMP,NRCAM,ABLIM1,SLC1A2,RPS6KA2,MAP3K5,NPAS3,TNIK,CSGALNACT1,HPSE2,SPON1,ADCY2,ATP13A4,GPM6A,ATP1A2,SLC4A4,BMPR1B,PAMR1,RORA,DCLK2,NRG3,EFEMP1,NTRK2,TRPM3,PARD3,GPC5,TRPS1,NAV3,DTNA,MSI2,HIF3A
3.735e-02	-3.29	urinary_tract	COSMIC cancer mutations	urinary_tract	14112	45	16828	48	GLIS3,LSAMP,SORBS1,PTPRZ1,NEBL,MAP3K5,NRCAM,RPS6KA2,SLC1A2,ABLIM1,FMN2,RFX4,MGAT4C,PITPNC1,CPE,SOX5,MACF1,DPP10,CLU,CTNND2,RORA,PAMR1,NRG3,DCLK2,BMPR1B,SLC4A4,MSI2,DTNA,HIF3A,PARD3,TRPM3,NTRK2,EFEMP1,NAV3,TRPS1,GPC5,CSGALNACT1,HPSE2,NPAS3,TNIK,GPM6A,ADCY2,ATP13A4,SPON1,ATP1A2
3.738e-02	-3.29	bone-humerus-Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour	COSMIC cancer mutations	bone-humerus-Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour	107	2	16828	48	NEBL,HIF3A
3.756e-02	-3.28	ANKRD26 (ankyrin repeat domain containing 26)	protein interactions	22852	119	2	19454	50	PARD3,NTRK2
3.759e-02	-3.28	human chr8p21.1	chromosome location	human chr8p21.1	20	1	26134	50	CLU
3.764e-02	-3.28	HCO3TRNSPORT	prints domains	PR01231	10	1	5227	20	SLC4A4
3.777e-02	-3.28	regulation of circadian rhythm	biological process	GO:0042752	114	2	18204	49	MAPK10,RORA
3.788e-02	-3.27	PCSK1N (proprotein convertase subtilisin/kexin type 1 inhibitor)	protein interactions	27344	15	1	19454	50	MGAT4C
3.788e-02	-3.27	GSTM1 (glutathione S-transferase mu 1)	protein interactions	2944	15	1	19454	50	MAP3K5
3.788e-02	-3.27	TAFA5 (TAFA chemokine like family member 5)	protein interactions	25817	15	1	19454	50	NEBL
3.788e-02	-3.27	XIRP1 (xin actin binding repeat containing 1)	protein interactions	165904	15	1	19454	50	NEBL
3.788e-02	-3.27	IGSF1 (immunoglobulin superfamily member 1)	protein interactions	3547	15	1	19454	50	BMPR1B
3.788e-02	-3.27	MIP	pfam domains	PF00230	14	1	17795	49	AQP4
3.788e-02	-3.27	GATA	pfam domains	PF00320	14	1	17795	49	TRPS1
3.808e-02	-3.27	learning or memory	biological process	GO:0007611	276	3	18204	49	ATP1A2,PTPRZ1,NTRK2
3.810e-02	-3.27	CEP128 (centrosomal protein 128)	protein interactions	145508	289	3	19454	50	NEBL,SORBS1,ABLIM1
3.819e-02	-3.27	circulatory system development	biological process	GO:0072359	933	6	18204	49	NRCAM,NEBL,RORA,CPE,HIF3A,NTRK2
3.850e-02	-3.26	Passive transport by Aquaporins	REACTOME pathways	R-HSA-432047	13	1	10285	31	AQP4
3.850e-02	-3.26	ERBB2 Activates PTK6 Signaling	REACTOME pathways	R-HSA-8847993	13	1	10285	31	NRG3
3.855e-02	-3.26	axolemma	cellular component	GO:0030673	15	1	19108	50	SLC1A2
3.870e-02	-3.25	neuronal cell body	cellular component	GO:0043025	489	4	19108	50	ATP1A2,CTNND2,BMPR1B,GPM6A
3.878e-02	-3.25	actin filament organization	biological process	GO:0007015	278	3	18204	49	SORBS1,NEBL,FMN2
3.884e-02	-3.25	lung-carcinoma-adenocarcinoma	COSMIC cancer mutations	lung-carcinoma-adenocarcinoma	15133	47	16828	48	PTPRZ1,NEBL,GLIS3,SORBS1,LSAMP,NRCAM,RPS6KA2,NKAIN3,SLC1A2,ABLIM1,MAP3K5,AQP4,PITPNC1,RFX4,FMN2,MGAT4C,DPP10,CLU,CTNND2,CPE,SOX5,MACF1,BMPR1B,SLC4A4,RORA,PAMR1,NRG3,DCLK2,PARD3,TRPM3,NTRK2,EFEMP1,NAV3,TRPS1,GPC5,MSI2,DTNA,HIF3A,NPAS3,TNIK,CSGALNACT1,HPSE2,GPM6A,ADCY2,ATP13A4,SPON1,ATP1A2
3.886e-02	-3.25	Salivary secretion	KEGG pathways	hsa04970	90	2	7161	25	ATP1A2,ADCY2
3.886e-02	-3.25	Salivary secretion	KEGG pathways	ko04970	90	2	7161	25	ATP1A2,ADCY2
3.887e-02	-3.25	striated_muscle	COSMIC cancer mutations	striated_muscle	4228	18	16828	48	NPAS3,PTPRZ1,PAMR1,RORA,FMN2,GLIS3,SORBS1,DPP10,PARD3,TRPM3,TRPS1,CLU,CTNND2,SPON1,ADCY2,MAP3K5,MACF1,AQP4
3.894e-02	-3.25	localization	biological process	GO:0051179	4474	18	18204	49	PARD3,ATP1A2,FMN2,SLC4A4,DCLK2,TRPM3,MACF1,CPE,TNIK,AQP4,ATP13A4,PITPNC1,DPP10,NRCAM,SLC1A2,GPM6A,NTRK2,CLU
3.934e-02	-3.24	SH3DOMAIN	prints domains	PR00452	83	2	5227	20	SORBS1,NEBL
3.943e-02	-3.23	human chr10q23.1	chromosome location	human chr10q23.1	21	1	26134	50	NRG3
3.943e-02	-3.23	human chr13q31.3	chromosome location	human chr13q31.3	21	1	26134	50	GPC5
3.943e-02	-3.23	human chr4q32.3	chromosome location	human chr4q32.3	21	1	26134	50	CPE
3.948e-02	-3.23	glycoprotein biosynthetic process	biological process	GO:0009101	280	3	18204	49	CSGALNACT1,MGAT4C,BMPR1B
3.953e-02	-3.23	chondroitin sulfate biosynthesis	BIOCYC pathways	META_PWY-6569	18	1	902	2	CSGALNACT1
3.964e-02	-3.23	protein homotrimerization	biological process	GO:0070207	15	1	18204	49	SLC1A2
3.964e-02	-3.23	peripheral nervous system neuron differentiation	biological process	GO:0048934	15	1	18204	49	NTRK2
3.964e-02	-3.23	intracellular potassium ion homeostasis	biological process	GO:0030007	15	1	18204	49	ATP1A2
3.964e-02	-3.23	cerebellar Purkinje cell layer formation	biological process	GO:0021694	15	1	18204	49	RORA
3.964e-02	-3.23	pyramidal neuron differentiation	biological process	GO:0021859	15	1	18204	49	DCLK2
3.964e-02	-3.23	p38MAPK cascade	biological process	GO:0038066	15	1	18204	49	MAP3K5
3.964e-02	-3.23	positive regulation of glycogen biosynthetic process	biological process	GO:0045725	15	1	18204	49	SORBS1
3.964e-02	-3.23	regulation of neuron projection arborization	biological process	GO:0150011	15	1	18204	49	MACF1
3.964e-02	-3.23	negative regulation of sodium ion transmembrane transport	biological process	GO:1902306	15	1	18204	49	ATP1A2
3.964e-02	-3.23	neuroblast division	biological process	GO:0055057	15	1	18204	49	SOX5
3.964e-02	-3.23	peripheral nervous system neuron development	biological process	GO:0048935	15	1	18204	49	NTRK2
3.972e-02	-3.23	microtubule binding	molecular function	GO:0008017	279	3	18094	49	MACF1,DCLK2,NAV3
3.975e-02	-3.23	Znf_GATA	interpro domains	IPR000679	15	1	18521	50	TRPS1
3.975e-02	-3.23	FH2_Formin	interpro domains	IPR015425	15	1	18521	50	FMN2
3.975e-02	-3.23	ATPase_P-typ_cation-transptr_C	interpro domains	IPR006068	15	1	18521	50	ATP1A2
3.975e-02	-3.23	FH2_Formin_sf	interpro domains	IPR042201	15	1	18521	50	FMN2
3.975e-02	-3.23	CNH_dom	interpro domains	IPR001180	15	1	18521	50	TNIK
3.988e-02	-3.22	filamin binding	molecular function	GO:0031005	15	1	18094	49	NEBL
3.988e-02	-3.22	tropomyosin binding	molecular function	GO:0005523	15	1	18094	49	NEBL
3.988e-02	-3.22	phosphatidylglycerol binding	molecular function	GO:1901611	15	1	18094	49	PITPNC1
3.988e-02	-3.22	neurexin family protein binding	molecular function	GO:0042043	15	1	18094	49	CPE
3.997e-02	-3.22	Bone Morphogenic Protein (BMP) Signalling and Regulation	WikiPathways	WP1425	12	1	5310	18	BMPR1B
4.002e-02	-3.22	solute:monoatomic cation symporter activity	molecular function	GO:0015294	117	2	18094	49	SLC4A4,SLC1A2
4.002e-02	-3.22	calcium channel activity	molecular function	GO:0005262	117	2	18094	49	TRPM3,GPM6A
4.035e-02	-3.21	ADAM18 (ADAM metallopeptidase domain 18)	protein interactions	8749	16	1	19454	50	RPS6KA2
4.035e-02	-3.21	KLHL25 (kelch like family member 25)	protein interactions	64410	16	1	19454	50	RPS6KA2
4.035e-02	-3.21	CDH12 (cadherin 12)	protein interactions	1010	16	1	19454	50	CTNNA2
4.035e-02	-3.21	SAPCD1 (suppressor APC domain containing 1)	protein interactions	401251	16	1	19454	50	CTNNA2
4.035e-02	-3.21	AMMECR1L (AMMECR1 like)	protein interactions	83607	16	1	19454	50	MACF1
4.035e-02	-3.21	GALNT13 (polypeptide N-acetylgalactosaminyltransferase 13)	protein interactions	114805	16	1	19454	50	TNIK
4.045e-02	-3.21	GnRH signaling pathway	KEGG pathways	hsa04912	92	2	7161	25	ADCY2,MAPK10
4.045e-02	-3.21	GnRH signaling pathway	KEGG pathways	ko04912	92	2	7161	25	ADCY2,MAPK10
4.053e-02	-3.21	Cation_ATPase_C	pfam domains	PF00689	15	1	17795	49	ATP1A2
4.053e-02	-3.21	CNH	pfam domains	PF00780	15	1	17795	49	TNIK
4.053e-02	-3.21	FH2	pfam domains	PF02181	15	1	17795	49	FMN2
4.060e-02	-3.20	MAPK	prosite domains	PS01351	12	1	12186	42	MAPK10
4.061e-02	-3.20	stomach-carcinoma-adenocarcinoma	COSMIC cancer mutations	stomach-carcinoma-adenocarcinoma	15150	47	16828	48	DPP10,CTNND2,CLU,CPE,SOX5,MACF1,PITPNC1,MGAT4C,RFX4,FMN2,NRCAM,ABLIM1,SLC1A2,RPS6KA2,MAP3K5,AQP4,NEBL,PTPRZ1,GLIS3,LSAMP,SORBS1,SPON1,ATP13A4,ADCY2,GPM6A,ATP1A2,NPAS3,TNIK,CSGALNACT1,HPSE2,RBMS3,EFEMP1,NTRK2,TRPM3,PARD3,TRPS1,GPC5,NAV3,DTNA,MSI2,HIF3A,SLC4A4,BMPR1B,PAMR1,RORA,DCLK2,NRG3
4.070e-02	-3.20	SH3	prosite domains	PS50002	222	3	12186	42	NEBL,SORBS1,MACF1
4.079e-02	-3.20	TJP1 (tight junction protein 1)	protein interactions	7082	297	3	19454	50	PARD3,NEBL,DTNA
4.099e-02	-3.19	Transport of inorganic cations/anions and amino acids/oligopeptides	REACTOME pathways	R-HSA-425393	107	2	10285	31	SLC4A4,SLC1A2
4.106e-02	-3.19	SOCS6 (suppressor of cytokine signaling 6)	protein interactions	9306	125	2	19454	50	EFEMP1,BMPR1B
4.107e-02	-3.19	postsynaptic density, intracellular component	cellular component	GO:0099092	16	1	19108	50	TNIK
4.112e-02	-3.19	regulation of transmembrane transport	biological process	GO:0034762	485	4	18204	49	SORBS1,SLC1A2,DPP10,ATP1A2
4.112e-02	-3.19	export from cell	biological process	GO:0140352	485	4	18204	49	ATP1A2,CPE,NTRK2,SLC4A4
4.127e-02	-3.19	human chr3q13.31	chromosome location	human chr3q13.31	22	1	26134	50	LSAMP
4.141e-02	-3.18	DCC mediated attractive signaling	REACTOME pathways	R-HSA-418885	14	1	10285	31	ABLIM1
4.141e-02	-3.18	SHC1 events in ERBB4 signaling	REACTOME pathways	R-HSA-1250347	14	1	10285	31	NRG3
4.144e-02	-3.18	striated muscle contraction	biological process	GO:0006941	120	2	18204	49	ATP1A2,DTNA
4.166e-02	-3.18	SYP (synaptophysin)	protein interactions	6855	126	2	19454	50	GPM6A,PITPNC1
4.176e-02	-3.18	Glycerol uptake facilitator protein	gene3d domains	1.20.1080.10	14	1	14470	44	AQP4
4.192e-02	-3.17	central_nervous_system-brainstem-glioma-oligoastrocytoma_Grade_III	COSMIC cancer mutations	central_nervous_system-brainstem-glioma-oligoastrocytoma_Grade_III	114	2	16828	48	SOX5,SLC1A2
4.223e-02	-3.16	regulation of respiratory system process	biological process	GO:0044065	16	1	18204	49	ATP1A2
4.223e-02	-3.16	insulin metabolic process	biological process	GO:1901142	16	1	18204	49	CPE
4.223e-02	-3.16	nonribosomal peptide biosynthetic process	biological process	GO:0019184	16	1	18204	49	SLC1A2
4.223e-02	-3.16	locomotory exploration behavior	biological process	GO:0035641	16	1	18204	49	ATP1A2
4.223e-02	-3.16	regulation of amino acid transmembrane transport	biological process	GO:1903789	16	1	18204	49	ATP1A2
4.223e-02	-3.16	cardiac left ventricle morphogenesis	biological process	GO:0003214	16	1	18204	49	CPE
4.223e-02	-3.16	regulation of amino acid import across plasma membrane	biological process	GO:0010958	16	1	18204	49	ATP1A2
4.230e-02	-3.16	EGF-like_Ca-bd_dom	interpro domains	IPR001881	121	2	18521	50	EFEMP1,PAMR1
4.235e-02	-3.16	CarboxyPept-like_regulatory	interpro domains	IPR008969	16	1	18521	50	CPE
4.248e-02	-3.16	MAP kinase activity	molecular function	GO:0004707	16	1	18094	49	MAPK10
4.248e-02	-3.16	water channel activity	molecular function	GO:0015250	16	1	18094	49	AQP4
4.248e-02	-3.16	MAP kinase kinase activity	molecular function	GO:0004708	16	1	18094	49	MAPK10
4.248e-02	-3.16	adenylate cyclase activity	molecular function	GO:0004016	16	1	18094	49	ADCY2
4.248e-02	-3.16	oxysterol binding	molecular function	GO:0008142	16	1	18094	49	RORA
4.248e-02	-3.16	misfolded protein binding	molecular function	GO:0051787	16	1	18094	49	CLU
4.251e-02	-3.16	TRAF1 (TNF receptor associated factor 1)	protein interactions	7185	302	3	19454	50	GLIS3,MAP3K5,NEBL
4.282e-02	-3.15	CNTN2 (contactin 2)	protein interactions	6900	17	1	19454	50	NRCAM
4.282e-02	-3.15	NFASC (neurofascin)	protein interactions	23114	17	1	19454	50	NRCAM
4.282e-02	-3.15	DPP6 (dipeptidyl peptidase like 6)	protein interactions	1804	17	1	19454	50	GPM6A
4.282e-02	-3.15	ZNF358 (zinc finger protein 358)	protein interactions	140467	17	1	19454	50	EFEMP1
4.282e-02	-3.15	TAGAP (T cell activation RhoGTPase activating protein)	protein interactions	117289	17	1	19454	50	DTNA
4.282e-02	-3.15	Shcbp1 (Shc SH2-domain binding protein 1)	protein interactions	20419	17	1	19454	50	GPC5
4.282e-02	-3.15	RASL12 (RAS like family 12)	protein interactions	51285	17	1	19454	50	BMPR1B
4.282e-02	-3.15	TNNT2 (troponin T2, cardiac type)	protein interactions	7139	17	1	19454	50	MAP3K5
4.282e-02	-3.15	Sqstm1 (sequestosome 1)	protein interactions	18412	17	1	19454	50	BMPR1B
4.282e-02	-3.15	SEPSECS (Sep (O-phosphoserine) tRNA:Sec (selenocysteine) tRNA synthase)	protein interactions	51091	17	1	19454	50	ABLIM1
4.282e-02	-3.15	MSANTD2 (Myb/SANT DNA binding domain containing 2)	protein interactions	79684	17	1	19454	50	SOX5
4.286e-02	-3.15	TEAD2 (TEA domain transcription factor 2)	protein interactions	8463	128	2	19454	50	TRPS1,MAP3K5
4.286e-02	-3.15	ATF7IP (activating transcription factor 7 interacting protein)	protein interactions	55729	128	2	19454	50	SOX5,MACF1
4.287e-02	-3.15	Endocrine resistance	KEGG pathways	ko01522	95	2	7161	25	ADCY2,MAPK10
4.287e-02	-3.15	Endocrine resistance	KEGG pathways	hsa01522	95	2	7161	25	ADCY2,MAPK10
4.311e-02	-3.14	human chr5p15.31	chromosome location	human chr5p15.31	23	1	26134	50	ADCY2
4.312e-02	-3.14	regulation of multicellular organismal development	biological process	GO:2000026	1484	8	18204	49	PTPRZ1,EFEMP1,BMPR1B,MACF1,TRPS1,SOX5,NTRK2,PARD3
4.346e-02	-3.14	SLC38A2 (solute carrier family 38 member 2)	protein interactions	54407	129	2	19454	50	RPS6KA2,PARD3
4.358e-02	-3.13	apical dendrite	cellular component	GO:0097440	17	1	19108	50	CLU
4.359e-02	-3.13	ZnF_GATA	smart domains	SM00401	12	1	9717	36	TRPS1
4.367e-02	-3.13	monoatomic ion transport	biological process	GO:0006811	964	6	18204	49	ATP13A4,GPM6A,SLC4A4,SLC1A2,TRPM3,ATP1A2
4.391e-02	-3.13	CARBOXYPEPT_ZN_2	prosite domains	PS00133	13	1	12186	42	CPE
4.391e-02	-3.13	CARBOXYPEPT_ZN_1	prosite domains	PS00132	13	1	12186	42	CPE
4.407e-02	-3.12	DVL1 (dishevelled segment polarity protein 1)	protein interactions	1855	130	2	19454	50	RPS6KA2,PARD3
4.407e-02	-3.12	RSPH1 (radial spoke head component 1)	protein interactions	89765	130	2	19454	50	CLU,NRCAM
4.426e-02	-3.12	neuron projection terminus	cellular component	GO:0044306	128	2	19108	50	SLC1A2,NTRK2
4.430e-02	-3.12	ERBB2 Regulates Cell Motility	REACTOME pathways	R-HSA-6785631	15	1	10285	31	NRG3
4.430e-02	-3.12	Inhibition of adenylate cyclase pathway	REACTOME pathways	R-HSA-997269	15	1	10285	31	ADCY2
4.430e-02	-3.12	N-Glycan antennae elongation	REACTOME pathways	R-HSA-975577	15	1	10285	31	MGAT4C
4.430e-02	-3.12	Adenylate cyclase inhibitory pathway	REACTOME pathways	R-HSA-170670	15	1	10285	31	ADCY2
4.448e-02	-3.11	cytoskeleton	cellular component	GO:0005856	2412	11	19108	50	PARD3,CLU,SORBS1,NAV3,DTNA,NEBL,ABLIM1,MACF1,TNIK,CTNNA2,FMN2
4.452e-02	-3.11	Inflammatory mediator regulation of TRP channels	KEGG pathways	ko04750	97	2	7161	25	ADCY2,MAPK10
4.452e-02	-3.11	Inflammatory mediator regulation of TRP channels	KEGG pathways	hsa04750	97	2	7161	25	MAPK10,ADCY2
4.459e-02	-3.11	regulation of anatomical structure size	biological process	GO:0090066	498	4	18204	49	AQP4,NRCAM,MACF1,ATP1A2
4.461e-02	-3.11	actomyosin structure organization	biological process	GO:0031032	125	2	18204	49	SORBS1,NEBL
4.467e-02	-3.11	Formin, FH2 domain	gene3d domains	1.20.58.2220	15	1	14470	44	FMN2
4.468e-02	-3.11	membrane protein complex	cellular component	GO:0098796	1261	7	19108	50	BMPR1B,CTNNA2,DPP10,SORBS1,MAP3K5,SLC1A2,ATP1A2
4.477e-02	-3.11	Helix-loop-helix DNA-binding domain	gene3d domains	4.10.280.10	111	2	14470	44	HIF3A,NPAS3
4.481e-02	-3.11	positive regulation of cardiac muscle cell apoptotic process	biological process	GO:0010666	17	1	18204	49	MAP3K5
4.481e-02	-3.11	positive regulation of striated muscle cell apoptotic process	biological process	GO:0010663	17	1	18204	49	MAP3K5
4.481e-02	-3.11	reverse cholesterol transport	biological process	GO:0043691	17	1	18204	49	CLU
4.481e-02	-3.11	protein trimerization	biological process	GO:0070206	17	1	18204	49	SLC1A2
4.481e-02	-3.11	cell migration in hindbrain	biological process	GO:0021535	17	1	18204	49	CTNNA2
4.481e-02	-3.11	cellular response to reactive nitrogen species	biological process	GO:1902170	17	1	18204	49	MAP3K5
4.481e-02	-3.11	retinal rod cell differentiation	biological process	GO:0060221	17	1	18204	49	NTRK2
4.481e-02	-3.11	regulation of inclusion body assembly	biological process	GO:0090083	17	1	18204	49	CLU
4.481e-02	-3.11	regulation of amyloid fibril formation	biological process	GO:1905906	17	1	18204	49	CLU
4.481e-02	-3.11	microvillus assembly	biological process	GO:0030033	17	1	18204	49	TNIK
4.481e-02	-3.11	T-helper 17 type immune response	biological process	GO:0072538	17	1	18204	49	RORA
4.481e-02	-3.11	membrane depolarization during cardiac muscle cell action potential	biological process	GO:0086012	17	1	18204	49	ATP1A2
4.481e-02	-3.11	cGMP metabolic process	biological process	GO:0046068	17	1	18204	49	RORA
4.481e-02	-3.11	heparin metabolic process	biological process	GO:0030202	17	1	18204	49	CSGALNACT1
4.481e-02	-3.11	positive regulation of glycogen metabolic process	biological process	GO:0070875	17	1	18204	49	SORBS1
4.481e-02	-3.11	cell communication by electrical coupling involved in cardiac conduction	biological process	GO:0086064	17	1	18204	49	ATP1A2
4.484e-02	-3.10	protein modification process	biological process	GO:0036211	2058	10	18204	49	NTRK2,RPS6KA2,MGAT4C,MAP3K5,PTPRZ1,MAPK10,BMPR1B,EFEMP1,CPE,TNIK
4.493e-02	-3.10	A/G_cyclase_CS	interpro domains	IPR018297	17	1	18521	50	ADCY2
4.493e-02	-3.10	PAC	interpro domains	IPR001610	17	1	18521	50	HIF3A
4.493e-02	-3.10	CA_dom_sf	interpro domains	IPR036398	17	1	18521	50	PTPRZ1
4.493e-02	-3.10	CA_dom	interpro domains	IPR001148	17	1	18521	50	PTPRZ1
4.507e-02	-3.10	transmembrane receptor protein phosphatase activity	molecular function	GO:0019198	17	1	18094	49	PTPRZ1
4.507e-02	-3.10	transmembrane receptor protein tyrosine phosphatase activity	molecular function	GO:0005001	17	1	18094	49	PTPRZ1
4.514e-02	-3.10	skeletal system development	biological process	GO:0001501	500	4	18204	49	SOX5,BMPR1B,CSGALNACT1,TRPS1
4.525e-02	-3.10	limbic system development	biological process	GO:0021761	126	2	18204	49	DCLK2,ATP1A2
4.529e-02	-3.09	IRGC (immunity related GTPase cinema)	protein interactions	56269	18	1	19454	50	RPS6KA2
4.529e-02	-3.09	ORF45 (ORF45)	protein interactions	4961474	18	1	19454	50	RPS6KA2
4.529e-02	-3.09	TTC29 (tetratricopeptide repeat domain 29)	protein interactions	83894	18	1	19454	50	MACF1
4.529e-02	-3.09	CYP2E1 (cytochrome P450 family 2 subfamily E member 1)	protein interactions	1571	18	1	19454	50	CLU
4.529e-02	-3.09	Cnot2 (CCR4-NOT transcription complex, subunit 2)	protein interactions	72068	18	1	19454	50	MACF1
4.529e-02	-3.09	NECTIN1 (nectin cell adhesion molecule 1)	protein interactions	5818	18	1	19454	50	PARD3
4.529e-02	-3.09	NKIRAS1 (NFKB inhibitor interacting Ras like 1)	protein interactions	28512	18	1	19454	50	BMPR1B
4.529e-02	-3.09	ACAP1 (ArfGAP with coiled-coil, ankyrin repeat and PH domains 1)	protein interactions	9744	18	1	19454	50	NEBL
4.529e-02	-3.09	Tgfbr1 (transforming growth factor, beta receptor I)	protein interactions	21812	18	1	19454	50	BMPR1B
4.529e-02	-3.09	KLHL1 (kelch like family member 1)	protein interactions	57626	18	1	19454	50	BMPR1B
4.531e-02	-3.09	positive regulation of nervous system development	biological process	GO:0051962	296	3	18204	49	MACF1,PTPRZ1,NTRK2
4.573e-02	-3.08	carbohydrate derivative metabolic process	biological process	GO:1901135	975	6	18204	49	ADCY2,BMPR1B,CSGALNACT1,ATP1A2,RORA,MGAT4C
4.581e-02	-3.08	Carb_anhydrase	pfam domains	PF00194	17	1	17795	49	PTPRZ1
4.581e-02	-3.08	ZZ	pfam domains	PF00569	17	1	17795	49	DTNA
4.586e-02	-3.08	central_nervous_system-brain-glioma-astrocytoma_Grade_III	COSMIC cancer mutations	central_nervous_system-brain-glioma-astrocytoma_Grade_III	1419	8	16828	48	PARD3,TRPM3,GPC5,PAMR1,MAP3K5,ADCY2,NRG3,HPSE2
4.590e-02	-3.08	response to amino acid	biological process	GO:0043200	127	2	18204	49	NTRK2,SLC1A2
4.598e-02	-3.08	haematopoietic_and_lymphoid_tissue-abdomen-lymphoid_neoplasm-diffuse_large_B_cell_lymphoma	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue-abdomen-lymphoid_neoplasm-diffuse_large_B_cell_lymphoma	120	2	16828	48	CTNND2,FMN2
4.620e-02	-3.07	skin-head_neck-malignant_melanoma-superficial_spreading	COSMIC cancer mutations	skin-head_neck-malignant_melanoma-superficial_spreading	923	6	16828	48	CTNND2,MACF1,SORBS1,MGAT4C,ATP13A4,ADCY2
4.642e-02	-3.07	extracellular region	cellular component	GO:0005576	4350	17	19108	50	NRCAM,GPM6A,EFEMP1,PAMR1,TNIK,NRG3,HPSE2,CPE,SPON1,NEBL,PTPRZ1,GPC5,SLC4A4,LSAMP,CLU,AQP4,ATP1A2
4.648e-02	-3.07	ERK Pathway in Huntington's Disease	WikiPathways	WP3853	14	1	5310	18	NTRK2
4.653e-02	-3.07	NUFIP1 (nuclear FMR1 interacting protein 1)	protein interactions	26747	134	2	19454	50	GPM6A,CPE
4.659e-02	-3.07	Integrin-mediated Cell Adhesion	WikiPathways	WP185	103	2	5310	18	SORBS1,MAPK10
4.669e-02	-3.06	Activated TLR4 signalling	REACTOME pathways	R-HSA-166054	115	2	10285	31	RPS6KA2,MAPK10
4.677e-02	-3.06	human chr7q31.1	chromosome location	human chr7q31.1	25	1	26134	50	NRCAM
4.716e-02	-3.05	Myo1c (myosin IC)	protein interactions	17913	135	2	19454	50	ABLIM1,TRPS1
4.716e-02	-3.05	BMP4 (bone morphogenetic protein 4)	protein interactions	652	135	2	19454	50	CLU,BMPR1B
4.718e-02	-3.05	PI3K events in ERBB2 signaling	REACTOME pathways	R-HSA-1963642	16	1	10285	31	NRG3
4.718e-02	-3.05	PKA activation	REACTOME pathways	R-HSA-163615	16	1	10285	31	ADCY2
4.718e-02	-3.05	GRB2 events in ERBB2 signaling	REACTOME pathways	R-HSA-1963640	16	1	10285	31	NRG3
4.738e-02	-3.05	negative regulation of anoikis	biological process	GO:2000811	18	1	18204	49	NTRK2
4.738e-02	-3.05	cardiac myofibril assembly	biological process	GO:0055003	18	1	18204	49	NEBL
4.738e-02	-3.05	positive regulation of myelination	biological process	GO:0031643	18	1	18204	49	PARD3
4.738e-02	-3.05	positive regulation of circadian rhythm	biological process	GO:0042753	18	1	18204	49	RORA
4.738e-02	-3.05	response to misfolded protein	biological process	GO:0051788	18	1	18204	49	CLU
4.738e-02	-3.05	dendritic spine morphogenesis	biological process	GO:0060997	18	1	18204	49	CTNND2
4.738e-02	-3.05	negative regulation of sodium ion transport	biological process	GO:0010766	18	1	18204	49	ATP1A2
4.738e-02	-3.05	myelin maintenance	biological process	GO:0043217	18	1	18204	49	CLU
4.752e-02	-3.05	A/G_cyclase	interpro domains	IPR001054	18	1	18521	50	ADCY2
4.752e-02	-3.05	Nucleotide_cyclase	interpro domains	IPR029787	18	1	18521	50	ADCY2
4.766e-02	-3.04	transmembrane receptor protein tyrosine kinase activator activity	molecular function	GO:0030297	18	1	18094	49	NRG3
4.766e-02	-3.04	heparan sulfate proteoglycan binding	molecular function	GO:0043395	18	1	18094	49	HPSE2
4.766e-02	-3.04	acidic amino acid transmembrane transporter activity	molecular function	GO:0015172	18	1	18094	49	SLC1A2
4.766e-02	-3.04	phosphatidylcholine transporter activity	molecular function	GO:0008525	18	1	18094	49	PITPNC1
4.774e-02	-3.04	SPZ1 (spermatogenic leucine zipper 1)	protein interactions	84654	19	1	19454	50	DTNA
4.774e-02	-3.04	FBXO27 (F-box protein 27)	protein interactions	126433	19	1	19454	50	CLU
4.774e-02	-3.04	Trp53 (transformation related protein 53)	protein interactions	22059	19	1	19454	50	MAPK10
4.774e-02	-3.04	APOBEC3G (apolipoprotein B mRNA editing enzyme catalytic subunit 3G)	protein interactions	60489	19	1	19454	50	MAP3K5
4.774e-02	-3.04	TNR (tenascin R)	protein interactions	7143	19	1	19454	50	PTPRZ1
4.774e-02	-3.04	RIT2 (Ras like without CAAX 2)	protein interactions	6014	19	1	19454	50	DTNA
4.774e-02	-3.04	ZNF791 (zinc finger protein 791)	protein interactions	163049	19	1	19454	50	EFEMP1
4.774e-02	-3.04	CNTNAP4 (contactin associated protein family member 4)	protein interactions	85445	19	1	19454	50	MACF1
4.774e-02	-3.04	PHYHIPL (phytanoyl-CoA 2-hydroxylase interacting protein like)	protein interactions	84457	19	1	19454	50	GPM6A
4.774e-02	-3.04	C3orf62 (chromosome 3 open reading frame 62)	protein interactions	375341	19	1	19454	50	ATP1A2
4.774e-02	-3.04	ZNF627 (zinc finger protein 627)	protein interactions	199692	19	1	19454	50	EFEMP1
4.774e-02	-3.04	GCHFR (GTP cyclohydrolase I feedback regulator)	protein interactions	2644	19	1	19454	50	NEBL
4.774e-02	-3.04	OSM (oncostatin M)	protein interactions	5008	19	1	19454	50	TRPM3
4.788e-02	-3.04	Retrograde endocannabinoid signaling	KEGG pathways	hsa04723	101	2	7161	25	ADCY2,MAPK10
4.788e-02	-3.04	Retrograde endocannabinoid signaling	KEGG pathways	ko04723	101	2	7161	25	MAPK10,ADCY2
4.802e-02	-3.04	ductal_carcinoma	COSMIC cancer mutations	ductal_carcinoma	15798	48	16828	48	DPP10,CTNND2,CLU,CPE,SOX5,MACF1,PITPNC1,MGAT4C,FMN2,RFX4,NRCAM,ABLIM1,SLC1A2,NKAIN3,RPS6KA2,MAP3K5,AQP4,NEBL,PTPRZ1,GLIS3,LSAMP,SORBS1,SPON1,ADCY2,ATP13A4,GPM6A,ATP1A2,NPAS3,TNIK,CSGALNACT1,HPSE2,RBMS3,EFEMP1,NTRK2,TRPM3,PARD3,TRPS1,GPC5,NAV3,DTNA,MSI2,HIF3A,SLC4A4,BMPR1B,PAMR1,RORA,DCLK2,NRG3
4.844e-02	-3.03	Guanylate_cyc	pfam domains	PF00211	18	1	17795	49	ADCY2
4.859e-02	-3.02	cation-transporting ATPase complex	cellular component	GO:0090533	19	1	19108	50	ATP1A2
4.859e-02	-3.02	parallel fiber to Purkinje cell synapse	cellular component	GO:0098688	19	1	19108	50	GPM6A
4.859e-02	-3.02	postsynaptic specialization, intracellular component	cellular component	GO:0099091	19	1	19108	50	TNIK
4.859e-02	-3.02	human chr2p16.1	chromosome location	human chr2p16.1	26	1	26134	50	EFEMP1
4.859e-02	-3.02	human chr6q23.3	chromosome location	human chr6q23.3	26	1	26134	50	MAP3K5
4.859e-02	-3.02	human chr18q12.1	chromosome location	human chr18q12.1	26	1	26134	50	DTNA
4.875e-02	-3.02	chondrosarcoma	COSMIC cancer mutations	chondrosarcoma	1181	7	16828	48	SPON1,ADCY2,CPE,HPSE2,LSAMP,SLC4A4,NAV3
4.905e-02	-3.01	NFIB (nuclear factor I B)	protein interactions	4781	138	2	19454	50	TRPS1,SOX5
4.918e-02	-3.01	amino acid transport	biological process	GO:0006865	132	2	18204	49	SLC1A2,NTRK2
4.934e-02	-3.01	organonitrogen compound metabolic process	biological process	GO:1901564	4594	18	18204	49	ATP1A2,MGAT4C,RPS6KA2,CPE,TNIK,PTPRZ1,MAPK10,EFEMP1,CSGALNACT1,DPP10,MAP3K5,SPON1,SLC1A2,NTRK2,CLU,RORA,ADCY2,BMPR1B
4.937e-02	-3.01	positive regulation of cellular component biogenesis	biological process	GO:0044089	515	4	18204	49	CLU,GPM6A,NAV3,NTRK2
4.940e-02	-3.01	ACTA1 (actin alpha 1, skeletal muscle)	protein interactions	58	321	3	19454	50	DTNA,MACF1,SORBS1
4.968e-02	-3.00	SPCS2 (signal peptidase complex subunit 2)	protein interactions	9789	139	2	19454	50	MGAT4C,GPC5
4.968e-02	-3.00	MAGI1 (membrane associated guanylate kinase, WW and PDZ domain containing 1)	protein interactions	9223	139	2	19454	50	RPS6KA2,PARD3
4.983e-02	-3.00	PK_Tyr_Ser-Thr	pfam domains	PF07714	130	2	17795	49	NTRK2,BMPR1B
4.995e-02	-3.00	response to potassium ion	biological process	GO:0035864	19	1	18204	49	ATP1A2
4.995e-02	-3.00	negative regulation of peptidyl-threonine phosphorylation	biological process	GO:0010801	19	1	18204	49	PARD3
4.995e-02	-3.00	microvillus organization	biological process	GO:0032528	19	1	18204	49	TNIK
4.995e-02	-3.00	regulation of amyloid-beta clearance	biological process	GO:1900221	19	1	18204	49	CLU
4.995e-02	-3.00	regulation of neurotransmitter uptake	biological process	GO:0051580	19	1	18204	49	ATP1A2
4.995e-02	-3.00	chondroitin sulfate biosynthetic process	biological process	GO:0030206	19	1	18204	49	CSGALNACT1
4.995e-02	-3.00	cerebellar Purkinje cell layer morphogenesis	biological process	GO:0021692	19	1	18204	49	RORA