Gene Ontology Enrichment Results

Homer de novo Motif Enrichment Results
Known Motif Enrichment Results

Text file version of complete results (i.e. open with Excel)

biological process: Functional groupings of proteins (Gene Ontology)

molecular function: Mechanistic actions of proteins (Gene Ontology)

cellular component: Protein localization (Gene Ontology)

chromosome location: Genes with similar chromosome localization (NCBI Gene)

KEGG pathways: Groups of proteins in the same pathways (KEGG)

protein interactions: "Proteins interacting with a common protein (BIND, EcoCyc, HPRD)" (NCBI Gene)

interpro domains: Proteins with similar domains and features (Interpro)

pfam domains: Proteins with similar domains and features (Pfam)

smart domains: Proteins with similar domains and features (SMART)

gene3d domains: Proteins with similar domains and features (Gene3D)

prosite domains: Proteins with similar domains and features (Prosite)

prints domains: Proteins with similar domains and features (PRINTS)

MSigDB lists: "Genes sets for pathways, factor/miRNA target predictions, expression patterns, etc." (MSigDB)

BIOCYC pathways: Groups of proteins in the same pathways (BIOCYC)

COSMIC cancer mutations: Genes mutated in similar cancers (COSMIC)

GWAS genes: Genes mutated in similar diseases (GWAS Catalog)

Lipid Maps pathways: Groups of proteins in the same lipid pathways (Lipid Maps/Biosystems)

Pathway Interaction DB: Groups of proteins in the same pathways (Pathway Interaction Database)

REACTOME pathways: Groups of proteins in the same pathways (REACTOME)

SMPDB pathways: Groups of proteins in the same pathways (SMPDB)

WikiPathways: Groups of proteins in the same pathways (Wikipathways)

Enriched Categories

P-value	ln(P)	Term	GO Tree	GO ID	# of Genes in Term	# of Target Genes in Term	# of Total Genes	# of Target Genes	Common Genes
7.941e-13	-27.86	nervous system development	biological process	GO:0007399	2185	27	18204	50	MSI2,KALRN,NRG3,GPM6A,CAMK2G,DGKG,TNC,RORA,TNIK,PARD3,CTNNA2,CTNND2,DCLK2,NTRK2,ATP1A2,LSAMP,SOX5,NRCAM,NAV2,NRXN1,CNTN1,FAT3,SLC1A2,NAV3,RFX4,PLCB1,NTM
1.403e-11	-24.99	haematopoietic_and_lymphoid_tissue-haematopoietic_neoplasm	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue-haematopoietic_neoplasm	764	17	16828	48	ATP1A2,NTRK2,NAV2,PARD3,KALRN,RYR3,PLCB1,NRG3,NKAIN3,ADCY2,LSAMP,GPC5,DPP6,LRP1B,HPSE2,SLC1A2,SOX5
3.946e-11	-23.96	upper_aerodigestive_tract-mouth-carcinoma-squamous_cell_carcinoma	COSMIC cancer mutations	upper_aerodigestive_tract-mouth-carcinoma-squamous_cell_carcinoma	6953	42	16828	48	NRG3,FAT3,TNC,RYR3,PLCB1,MACF1,GPC5,ADCY2,NAV3,DGKG,SYNE1,KALRN,RFX4,NTM,FMN2,DTNA,SOX5,DCLK2,NRXN1,CAMK2G,CNTN1,TNIK,LRP1B,DPP6,NEBL,LSAMP,RORA,NRCAM,TRPM3,MGAT4C,ATP1A2,GPM6A,PARD3,NAV2,SLC4A4,SLC1A2,ABLIM1,SORBS1,PITPNC1,NHSL1,CTNND2,SFXN5
1.037e-10	-22.99	acute_lymphoblastic_B_cell_leukaemia	COSMIC cancer mutations	acute_lymphoblastic_B_cell_leukaemia	3828	32	16828	48	NAV3,NKAIN3,ADCY2,GPC5,RYR3,PLCB1,TNC,NRG3,FAT3,FMN2,NTM,SYNE1,KALRN,NRXN1,SOX5,HPSE2,DPP6,LRP1B,TNIK,CNTN1,NRCAM,LSAMP,RORA,NEBL,NAV2,PARD3,GPM6A,NTRK2,MGAT4C,SLC1A2,SLC4A4,CTNND2
1.037e-10	-22.99	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-acute_lymphoblastic_B_cell_leukaemia	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-acute_lymphoblastic_B_cell_leukaemia	3828	32	16828	48	CTNND2,SLC4A4,SLC1A2,NAV2,GPM6A,PARD3,MGAT4C,NTRK2,NRCAM,LSAMP,RORA,NEBL,LRP1B,DPP6,CNTN1,TNIK,NRXN1,SOX5,HPSE2,NTM,FMN2,KALRN,SYNE1,NKAIN3,NAV3,GPC5,ADCY2,TNC,RYR3,PLCB1,NRG3,FAT3
7.413e-10	-21.02	mantle_cell_lymphoma	COSMIC cancer mutations	mantle_cell_lymphoma	2849	27	16828	48	LRP1B,DPP6,CNTN1,SOX5,HPSE2,SYNE1,KALRN,RFX4,FMN2,GPC5,ADCY2,NKAIN3,NAV3,NRG3,TNC,RYR3,PLCB1,CTNND2,SFXN5,SLC1A2,GPM6A,PARD3,NAV2,TRPM3,NTRK2,LSAMP,NEBL
8.126e-10	-20.93	neurogenesis	biological process	GO:0022008	1334	19	18204	50	TNC,RORA,TNIK,NAV2,NRXN1,KALRN,DGKG,GPM6A,NRCAM,NAV3,DCLK2,CTNND2,NTRK2,SOX5,NTM,PARD3,CTNNA2,FAT3,CNTN1
1.832e-09	-20.12	system development	biological process	GO:0048731	3533	29	18204	50	NTM,RFX4,SYNE1,NAV3,PLCB1,FAT3,CNTN1,SLC1A2,NEBL,NAV2,NRXN1,NRCAM,NTRK2,CTNND2,DCLK2,SOX5,LSAMP,ATP1A2,CTNNA2,PARD3,RORA,TNIK,TNC,DGKG,GPM6A,CAMK2G,MSI2,KALRN,NRG3
1.893e-09	-20.09	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-mantle_cell_lymphoma	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-mantle_cell_lymphoma	2737	26	16828	48	SLC1A2,SFXN5,CTNND2,LSAMP,NEBL,NAV2,GPM6A,PARD3,NTRK2,SOX5,HPSE2,DPP6,LRP1B,CNTN1,NAV3,NKAIN3,ADCY2,GPC5,PLCB1,RYR3,TNC,NRG3,FMN2,RFX4,KALRN,SYNE1
1.996e-09	-20.03	chondroblastoma	COSMIC cancer mutations	chondroblastoma	534	13	16828	48	GPC5,ADCY2,LSAMP,NKAIN3,NRG3,PLCB1,RYR3,GPM6A,FMN2,SOX5,CTNND2,LRP1B,SFXN5
2.339e-09	-19.87	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-Burkitt_lymphoma	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-Burkitt_lymphoma	2119	23	16828	48	CNTN1,LRP1B,DPP6,HPSE2,SOX5,DGKG,KALRN,RFX4,FMN2,NRG3,RYR3,PLCB1,GPC5,ADCY2,NKAIN3,NHSL1,CTNND2,SLC1A2,NTRK2,PARD3,GPM6A,NAV2,LSAMP
2.339e-09	-19.87	Burkitt_lymphoma	COSMIC cancer mutations	Burkitt_lymphoma	2119	23	16828	48	LSAMP,NTRK2,NAV2,PARD3,GPM6A,SLC1A2,NHSL1,CTNND2,RYR3,PLCB1,NRG3,NKAIN3,ADCY2,GPC5,DGKG,FMN2,RFX4,KALRN,HPSE2,SOX5,CNTN1,DPP6,LRP1B
5.400e-09	-19.04	generation of neurons	biological process	GO:0048699	1158	17	18204	50	SOX5,NTM,NTRK2,DCLK2,CTNND2,FAT3,CTNNA2,CNTN1,PARD3,TNIK,NRXN1,RORA,TNC,NRCAM,DGKG,GPM6A,KALRN
5.425e-09	-19.03	neuron development	biological process	GO:0048666	859	15	18204	50	NRXN1,TNIK,TNC,GPM6A,DGKG,NRCAM,KALRN,NTRK2,DCLK2,CTNND2,NTM,CNTN1,CTNNA2,FAT3,PARD3
6.314e-09	-18.88	haematopoietic_and_lymphoid_tissue-lymph_node-lymphoid_neoplasm-mantle_cell_lymphoma	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue-lymph_node-lymphoid_neoplasm-mantle_cell_lymphoma	476	12	16828	48	NRG3,RYR3,PLCB1,LSAMP,GPC5,TRPM3,GPM6A,SYNE1,NAV2,SFXN5,CTNND2,LRP1B
1.048e-08	-18.37	haematopoietic_and_lymphoid_tissue-haematopoietic_neoplasm-myelodysplastic_syndrome	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue-haematopoietic_neoplasm-myelodysplastic_syndrome	1174	17	16828	48	TNIK,LRP1B,SLC1A2,HPSE2,SOX5,DCLK2,CAMK2G,NTRK2,ATP1A2,KALRN,PARD3,NAV2,NRG3,RYR3,ADCY2,LSAMP,NKAIN3
1.048e-08	-18.37	myelodysplastic_syndrome	COSMIC cancer mutations	myelodysplastic_syndrome	1174	17	16828	48	SOX5,CAMK2G,DCLK2,SLC1A2,HPSE2,LRP1B,TNIK,LSAMP,ADCY2,NKAIN3,NRG3,RYR3,KALRN,PARD3,NAV2,ATP1A2,NTRK2
1.069e-08	-18.35	prostate-carcinoma	COSMIC cancer mutations	prostate-carcinoma	9000	44	16828	48	NTRK2,TRPM3,PARD3,SLC4A4,SLC1A2,SORBS1,CTNND2,SFXN5,RYR3,NRG3,NKAIN3,NTM,FMN2,DTNA,HPSE2,DCLK2,NRXN1,CNTN1,DPP6,NEBL,NRCAM,RORA,LSAMP,NAV2,GPM6A,ABLIM1,NHSL1,SLC14A1,PITPNC1,TNC,PLCB1,FAT3,NAV3,GPC5,MACF1,ADCY2,DGKG,MSI2,KALRN,SYNE1,RFX4,SOX5,TNIK,LRP1B
1.088e-08	-18.34	mouth	COSMIC cancer mutations	mouth	9004	44	16828	48	CTNND2,SFXN5,SLC4A4,SLC1A2,SORBS1,NTRK2,ATP1A2,TRPM3,PARD3,CNTN1,DPP6,HPSE2,DCLK2,NRXN1,NTM,DTNA,FMN2,RYR3,NRG3,NHSL1,PITPNC1,ABLIM1,MGAT4C,NAV2,GPM6A,NEBL,NRCAM,RORA,LSAMP,TNIK,LRP1B,CAMK2G,SOX5,DGKG,SYNE1,KALRN,RFX4,TNC,PLCB1,FAT3,NAV3,GPC5,MACF1,ADCY2
1.170e-08	-18.26	lymph_node	COSMIC cancer mutations	lymph_node	1703	20	16828	48	TRPM3,NTRK2,PARD3,SYNE1,GPM6A,NAV2,DTNA,NEBL,NRG3,RYR3,PLCB1,GPC5,LSAMP,NAV3,TNIK,CTNND2,LRP1B,SFXN5,SOX5,CAMK2G
1.199e-08	-18.24	haematopoietic_and_lymphoid_tissue-haematopoietic_neoplasm-acute_myeloid_leukaemia_therapy_related	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue-haematopoietic_neoplasm-acute_myeloid_leukaemia_therapy_related	1523	19	16828	48	LRP1B,CTNND2,HPSE2,SOX5,DGKG,NTRK2,PARD3,KALRN,FMN2,NAV2,NRG3,NEBL,PLCB1,RYR3,RORA,LSAMP,ADCY2,GPC5,NKAIN3
1.199e-08	-18.24	acute_myeloid_leukaemia_therapy_related	COSMIC cancer mutations	acute_myeloid_leukaemia_therapy_related	1523	19	16828	48	NEBL,NRG3,RYR3,PLCB1,GPC5,RORA,ADCY2,LSAMP,NKAIN3,NTRK2,DGKG,KALRN,PARD3,NAV2,FMN2,HPSE2,SOX5,LRP1B,CTNND2
1.551e-08	-17.98	neuron differentiation	biological process	GO:0030182	1081	16	18204	50	PARD3,CTNNA2,FAT3,CNTN1,NTM,NTRK2,DCLK2,CTNND2,KALRN,NRCAM,DGKG,GPM6A,TNC,TNIK,NRXN1,RORA
1.746e-08	-17.86	cerebellum	COSMIC cancer mutations	cerebellum	769	14	16828	48	NRXN1,ABLIM1,HPSE2,DPP6,LRP1B,CTNND2,GPC5,NRCAM,NRG3,NEBL,RYR3,PLCB1,PARD3,NTRK2
2.213e-08	-17.63	central_nervous_system-cerebellum-primitive_neuroectodermal_tumour-medulloblastoma-SHH_subtype	COSMIC cancer mutations	central_nervous_system-cerebellum-primitive_neuroectodermal_tumour-medulloblastoma-SHH_subtype	653	13	16828	48	HPSE2,ABLIM1,NRXN1,CTNND2,LRP1B,DPP6,RYR3,PLCB1,NEBL,NRG3,NRCAM,NTRK2,PARD3
2.254e-08	-17.61	SHH_subtype	COSMIC cancer mutations	SHH_subtype	654	13	16828	48	NRCAM,NRG3,NEBL,PLCB1,RYR3,PARD3,NTRK2,NRXN1,ABLIM1,HPSE2,DPP6,LRP1B,CTNND2
2.762e-08	-17.40	multicellular organism development	biological process	GO:0007275	3957	29	18204	50	DGKG,GPM6A,CAMK2G,NRG3,KALRN,MSI2,TNIK,RORA,TNC,CTNNA2,PARD3,SOX5,LSAMP,ATP1A2,NTRK2,CTNND2,DCLK2,NRCAM,NAV2,NRXN1,NEBL,SLC1A2,FAT3,CNTN1,NTM,PLCB1,RFX4,SYNE1,NAV3
2.935e-08	-17.34	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-diffuse_large_B_cell_lymphoma	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-diffuse_large_B_cell_lymphoma	3608	28	16828	48	SLC1A2,CTNND2,NEBL,RORA,LSAMP,ATP1A2,GPM6A,PARD3,NAV2,HPSE2,SOX5,CNTN1,TNIK,DPP6,LRP1B,NRG3,PLCB1,RYR3,TNC,ADCY2,MACF1,GPC5,NAV3,NKAIN3,DGKG,KALRN,SYNE1,FMN2
3.024e-08	-17.31	diffuse_large_B_cell_lymphoma	COSMIC cancer mutations	diffuse_large_B_cell_lymphoma	4151	30	16828	48	GPC5,MACF1,ADCY2,NKAIN3,NAV3,NRG3,TNC,PLCB1,RYR3,KALRN,SYNE1,DTNA,FMN2,DGKG,SOX5,HPSE2,LRP1B,DPP6,CNTN1,TNIK,LSAMP,RORA,NEBL,GPM6A,PARD3,NAV2,NTRK2,ATP1A2,SLC1A2,CTNND2
3.102e-08	-17.29	plasma_cell_myeloma	COSMIC cancer mutations	plasma_cell_myeloma	1263	17	16828	48	NTRK2,SYNE1,GPM6A,NTM,FMN2,NEBL,NRG3,TNC,RYR3,MACF1,ADCY2,NAV3,TNIK,CTNND2,LRP1B,HPSE2,ABLIM1
3.102e-08	-17.29	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-plasma_cell_myeloma	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-plasma_cell_myeloma	1263	17	16828	48	NEBL,NRG3,TNC,RYR3,MACF1,ADCY2,NAV3,NTRK2,GPM6A,SYNE1,NTM,FMN2,HPSE2,ABLIM1,TNIK,LRP1B,CTNND2
3.501e-08	-17.17	right_lower_lobe	COSMIC cancer mutations	right_lower_lobe	5692	35	16828	48	DGKG,KALRN,SYNE1,DTNA,FMN2,NTM,NRG3,FAT3,RYR3,PLCB1,TNC,ADCY2,GPC5,MACF1,NAV3,NKAIN3,CNTN1,DPP6,LRP1B,HPSE2,SOX5,TRPM3,ATP1A2,MGAT4C,NTRK2,GPM6A,PARD3,NAV2,NEBL,LSAMP,NRCAM,SLC14A1,CTNND2,SLC4A4,SORBS1
3.501e-08	-17.17	lung-right_lower_lobe-carcinoma-adenocarcinoma	COSMIC cancer mutations	lung-right_lower_lobe-carcinoma-adenocarcinoma	5692	35	16828	48	DGKG,SYNE1,KALRN,DTNA,FMN2,NTM,NRG3,FAT3,PLCB1,RYR3,TNC,ADCY2,MACF1,GPC5,NAV3,NKAIN3,CNTN1,DPP6,LRP1B,HPSE2,SOX5,TRPM3,ATP1A2,MGAT4C,NTRK2,PARD3,GPM6A,NAV2,NEBL,LSAMP,NRCAM,SLC14A1,CTNND2,SLC4A4,SORBS1
5.405e-08	-16.73	central_nervous_system-brain-primitive_neuroectodermal_tumour-medulloblastoma	COSMIC cancer mutations	central_nervous_system-brain-primitive_neuroectodermal_tumour-medulloblastoma	7205	39	16828	48	CNTN1,TNIK,LRP1B,DPP6,HPSE2,DCLK2,NRXN1,SOX5,DGKG,NTM,FMN2,KALRN,SYNE1,RFX4,RYR3,PLCB1,FAT3,NRG3,NKAIN3,NAV3,GPC5,MACF1,ADCY2,NHSL1,PITPNC1,CTNND2,SFXN5,SLC4A4,SLC1A2,ABLIM1,SORBS1,NTRK2,TRPM3,NAV2,PARD3,GPM6A,NEBL,RORA,LSAMP
7.535e-08	-16.40	PRNP (prion protein (Kanno blood group))	protein interactions	5621	1118	15	19454	50	SLC4A4,TRPM3,GPM6A,NHSL1,SORBS1,MSI2,TNC,PLCB1,MACF1,DPP6,CNTN1,ABLIM1,CAMK2G,ATP1A2,LSAMP
1.117e-07	-16.01	upper_aerodigestive_tract-larynx-carcinoma-squamous_cell_carcinoma	COSMIC cancer mutations	upper_aerodigestive_tract-larynx-carcinoma-squamous_cell_carcinoma	1946	20	16828	48	HPSE2,SLC4A4,NRXN1,RBMS3,SOX5,TNIK,CNTN1,DPP6,LRP1B,RYR3,PLCB1,FAT3,NEBL,NAV3,RORA,MACF1,MGAT4C,FMN2,GPM6A,SYNE1
1.136e-07	-15.99	larynx	COSMIC cancer mutations	larynx	1948	20	16828	48	RBMS3,NRXN1,SOX5,SLC4A4,HPSE2,LRP1B,DPP6,CNTN1,TNIK,NAV3,MACF1,RORA,PLCB1,RYR3,NEBL,FAT3,FMN2,SYNE1,GPM6A,MGAT4C
1.245e-07	-15.90	CTNNA1 (catenin alpha 1)	protein interactions	1495	325	9	19454	50	TNIK,MACF1,SORBS1,PARD3,NEBL,DTNA,ABLIM1,CTNNA2,NHSL1
2.374e-07	-15.25	pharynx	COSMIC cancer mutations	pharynx	2696	23	16828	48	LRP1B,DPP6,SYNE1,RFX4,DTNA,FMN2,DGKG,GPC5,MACF1,FAT3,NRG3,RYR3,CTNND2,SFXN5,PITPNC1,NHSL1,SLC14A1,SORBS1,SLC4A4,SLC1A2,NTRK2,ATP1A2,NRCAM
2.662e-07	-15.14	central_nervous_system-brain-primitive_neuroectodermal_tumour-medulloblastoma-large_cell	COSMIC cancer mutations	central_nervous_system-brain-primitive_neuroectodermal_tumour-medulloblastoma-large_cell	1117	15	16828	48	NRG3,RYR3,PLCB1,ADCY2,GPC5,DGKG,SYNE1,KALRN,PARD3,FMN2,NAV2,SLC1A2,SOX5,DPP6,LRP1B
2.687e-07	-15.13	cell periphery	cellular component	GO:0071944	6020	33	19108	49	NRXN1,TRPM3,CNTN1,HPSE2,NAV2,NRG3,SLC14A1,SLC4A4,TNC,DGKG,NRCAM,PARD3,MACF1,NKAIN3,FMN2,DTNA,ADCY2,DPP6,LSAMP,SORBS1,RYR3,ATP1A2,SLC1A2,CTNND2,CTNNA2,GPC5,NTRK2,LRP1B,MAPK10,TNIK,GPM6A,SYNE1,NTM
2.830e-07	-15.08	regulation of neuron projection development	biological process	GO:0010975	443	10	18204	50	CNTN1,CAMK2G,DGKG,CTNNA2,FAT3,NRCAM,SYNE1,NTRK2,MACF1,TNIK
3.366e-07	-14.90	bone-tibia-other-chondroblastoma	COSMIC cancer mutations	bone-tibia-other-chondroblastoma	98	6	16828	48	NKAIN3,LSAMP,PLCB1,CTNND2,GPM6A,LRP1B
3.720e-07	-14.80	central_nervous_system-brainstem-glioma-astrocytoma_Grade_IV	COSMIC cancer mutations	central_nervous_system-brainstem-glioma-astrocytoma_Grade_IV	2531	22	16828	48	TNIK,DPP6,LRP1B,HPSE2,SOX5,FMN2,KALRN,SYNE1,RYR3,PLCB1,NRG3,NKAIN3,ADCY2,GPC5,SLC14A1,SFXN5,CTNND2,NAV2,PARD3,GPM6A,RORA,LSAMP
3.885e-07	-14.76	chronic_lymphocytic_leukaemia-small_lymphocytic_lymphoma	COSMIC cancer mutations	chronic_lymphocytic_leukaemia-small_lymphocytic_lymphoma	3511	26	16828	48	CTNND2,PITPNC1,SLC4A4,NAV2,PARD3,NTRK2,MGAT4C,TRPM3,NRCAM,LSAMP,LRP1B,DPP6,TNIK,HPSE2,DTNA,FMN2,MSI2,SYNE1,KALRN,GPC5,MACF1,ADCY2,PLCB1,RYR3,NRG3,FAT3
3.885e-07	-14.76	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-chronic_lymphocytic_leukaemia-small_lymphocytic_lymphoma	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-chronic_lymphocytic_leukaemia-small_lymphocytic_lymphoma	3511	26	16828	48	DTNA,FMN2,MSI2,KALRN,SYNE1,MACF1,GPC5,ADCY2,PLCB1,RYR3,FAT3,NRG3,LRP1B,DPP6,TNIK,HPSE2,NAV2,PARD3,NTRK2,MGAT4C,TRPM3,NRCAM,LSAMP,CTNND2,PITPNC1,SLC4A4
4.244e-07	-14.67	scalp	COSMIC cancer mutations	scalp	2110	20	16828	48	FMN2,NTM,SYNE1,ATP1A2,NAV3,NRCAM,LSAMP,RORA,MACF1,GPC5,PLCB1,TNC,NEBL,CNTN1,NRXN1,CAMK2G,RBMS3,SOX5,SORBS1,SLC4A4
4.831e-07	-14.54	cell differentiation	biological process	GO:0030154	3645	26	18204	50	PARD3,CTNNA2,NHSL1,SOX5,CTNND2,NTRK2,DCLK2,MSI2,KALRN,DGKG,CAMK2G,GPM6A,TNC,TNIK,RORA,NEBL,FAT3,CNTN1,PLCB1,SYNE1,FMN2,NAV3,NTM,NRCAM,NAV2,NRXN1
4.913e-07	-14.53	cellular developmental process	biological process	GO:0048869	3648	26	18204	50	TNC,RORA,TNIK,MSI2,KALRN,DGKG,GPM6A,CAMK2G,NHSL1,CTNND2,NTRK2,DCLK2,SOX5,PARD3,CTNNA2,NAV2,NRXN1,NRCAM,SYNE1,NAV3,FMN2,PLCB1,NTM,FAT3,CNTN1,NEBL
6.436e-07	-14.26	plasma membrane	cellular component	GO:0005886	5538	31	19108	49	TRPM3,NRXN1,HPSE2,CNTN1,SLC14A1,NRG3,NRCAM,SLC4A4,DGKG,PARD3,NKAIN3,MACF1,LSAMP,SORBS1,FMN2,DTNA,DPP6,ADCY2,ATP1A2,RYR3,CTNND2,SLC1A2,CTNNA2,NTRK2,GPC5,LRP1B,SYNE1,NTM,MAPK10,TNIK,GPM6A
6.984e-07	-14.17	brainstem	COSMIC cancer mutations	brainstem	3102	24	16828	48	GPM6A,PARD3,NAV2,RORA,LSAMP,SFXN5,CTNND2,SLC14A1,SLC1A2,SYNE1,KALRN,FMN2,ADCY2,GPC5,NKAIN3,NRG3,RYR3,PLCB1,TNC,DPP6,LRP1B,TNIK,SOX5,HPSE2
7.886e-07	-14.05	soft_tissue-blood_vessel-angiosarcoma	COSMIC cancer mutations	soft_tissue-blood_vessel-angiosarcoma	2192	20	16828	48	DPP6,LRP1B,CTNND2,SLC1A2,HPSE2,SOX5,NTRK2,FMN2,NAV2,SYNE1,PARD3,GPM6A,PLCB1,RYR3,NRG3,NEBL,NKAIN3,LSAMP,ADCY2,GPC5
7.886e-07	-14.05	angiosarcoma	COSMIC cancer mutations	angiosarcoma	2192	20	16828	48	PARD3,GPM6A,SYNE1,FMN2,NAV2,NTRK2,ADCY2,LSAMP,GPC5,NKAIN3,NRG3,NEBL,RYR3,PLCB1,DPP6,CTNND2,LRP1B,SOX5,SLC1A2,HPSE2
8.927e-07	-13.93	anatomical structure development	biological process	GO:0048856	5207	31	18204	50	PLCB1,SYNE1,RFX4,FMN2,NAV3,NTM,NEBL,SLC1A2,FAT3,CNTN1,NRXN1,NAV2,NRCAM,ABLIM1,ATP1A2,SOX5,LSAMP,CTNND2,NTRK2,DCLK2,PARD3,CTNNA2,TNC,TNIK,RORA,NRG3,MSI2,KALRN,DGKG,CAMK2G,GPM6A
9.065e-07	-13.91	blood_vessel	COSMIC cancer mutations	blood_vessel	2211	20	16828	48	RYR3,PLCB1,NEBL,NRG3,NKAIN3,GPC5,LSAMP,ADCY2,NTRK2,NAV2,FMN2,GPM6A,SYNE1,PARD3,SLC1A2,HPSE2,SOX5,LRP1B,CTNND2,DPP6
1.066e-06	-13.75	upper_aerodigestive_tract-mouth-carcinoma	COSMIC cancer mutations	upper_aerodigestive_tract-mouth-carcinoma	6426	35	16828	48	RFX4,SYNE1,KALRN,FMN2,NTM,DGKG,ADCY2,GPC5,MACF1,NAV3,NRG3,FAT3,RYR3,PLCB1,TNC,DPP6,LRP1B,CNTN1,SOX5,HPSE2,GPM6A,PARD3,NAV2,TRPM3,MGAT4C,RORA,NRCAM,SFXN5,CTNND2,PITPNC1,NHSL1,SORBS1,SLC1A2,ABLIM1,SLC4A4
1.247e-06	-13.60	endometrium-carcinoma-serous_carcinoma	COSMIC cancer mutations	endometrium-carcinoma-serous_carcinoma	1442	16	16828	48	TRPM3,FMN2,SYNE1,PARD3,RYR3,FAT3,LSAMP,GPC5,TNIK,CNTN1,DPP6,CTNND2,LRP1B,SLC4A4,NRXN1,SORBS1
1.436e-06	-13.45	Ig_I-set	interpro domains	IPR013098	132	6	18521	50	NTRK2,NRCAM,CNTN1,KALRN,NTM,LSAMP
1.472e-06	-13.43	regulation of plasma membrane bounded cell projection organization	biological process	GO:0120035	666	11	18204	50	CAMK2G,GPM6A,DGKG,NRCAM,MACF1,TNIK,CNTN1,CTNNA2,FAT3,SYNE1,NTRK2
1.600e-06	-13.35	I-set	pfam domains	PF07679	132	6	17795	49	NRCAM,NTRK2,LSAMP,CNTN1,KALRN,NTM
1.880e-06	-13.18	regulation of cell projection organization	biological process	GO:0031344	683	11	18204	50	FAT3,CTNNA2,CNTN1,SYNE1,NTRK2,NRCAM,DGKG,CAMK2G,GPM6A,TNIK,MACF1
1.912e-06	-13.17	oesophagus-middle_third-carcinoma-squamous_cell_carcinoma	COSMIC cancer mutations	oesophagus-middle_third-carcinoma-squamous_cell_carcinoma	3531	25	16828	48	SOX5,HPSE2,LRP1B,TNIK,MACF1,GPC5,ADCY2,NAV3,NRG3,FAT3,TNC,RYR3,SYNE1,FMN2,DGKG,SLC4A4,ABLIM1,CTNND2,NHSL1,NEBL,PARD3,GPM6A,NAV2,TRPM3,ATP1A2
1.926e-06	-13.16	central nervous system development	biological process	GO:0007417	995	13	18204	50	RFX4,PLCB1,RORA,DCLK2,NTRK2,ATP1A2,NAV2,MSI2,NRG3,CTNNA2,CNTN1,NRCAM,SLC1A2
1.933e-06	-13.16	middle_third	COSMIC cancer mutations	middle_third	3533	25	16828	48	HPSE2,SOX5,TNIK,LRP1B,TNC,RYR3,NRG3,FAT3,NAV3,GPC5,MACF1,ADCY2,DGKG,FMN2,SYNE1,SLC4A4,ABLIM1,NHSL1,CTNND2,NEBL,ATP1A2,TRPM3,NAV2,GPM6A,PARD3
1.935e-06	-13.16	bone-humerus-other-chondroblastoma	COSMIC cancer mutations	bone-humerus-other-chondroblastoma	301	8	16828	48	LRP1B,GPM6A,SFXN5,FMN2,GPC5,SOX5,ADCY2,NKAIN3
2.083e-06	-13.08	developmental process	biological process	GO:0032502	5716	32	18204	50	PARD3,CTNNA2,NHSL1,NTRK2,DCLK2,CTNND2,LSAMP,SOX5,ATP1A2,MSI2,KALRN,NRG3,DGKG,CAMK2G,GPM6A,TNC,RORA,TNIK,FAT3,CNTN1,NEBL,SLC1A2,SYNE1,RFX4,NAV3,FMN2,PLCB1,NTM,NRCAM,ABLIM1,NRXN1,NAV2
2.165e-06	-13.04	neuron projection development	biological process	GO:0031175	693	11	18204	50	NRCAM,CTNNA2,FAT3,CNTN1,GPM6A,PARD3,KALRN,TNIK,NRXN1,CTNND2,TNC
2.308e-06	-12.98	action potential propagation	biological process	GO:0098870	10	3	18204	50	NRCAM,ATP1A2,NTRK2
2.308e-06	-12.98	neuronal action potential propagation	biological process	GO:0019227	10	3	18204	50	NRCAM,ATP1A2,NTRK2
2.565e-06	-12.87	humerus	COSMIC cancer mutations	humerus	546	10	16828	48	GPC5,SOX5,ADCY2,NKAIN3,NEBL,LRP1B,KALRN,GPM6A,SFXN5,FMN2
2.846e-06	-12.77	bone	COSMIC cancer mutations	bone	8157	39	16828	48	SORBS1,SLC4A4,ABLIM1,CTNND2,SFXN5,NRCAM,LSAMP,RORA,NEBL,NAV2,PARD3,GPM6A,NTRK2,ATP1A2,TRPM3,DCLK2,NRXN1,CAMK2G,SOX5,HPSE2,LRP1B,DPP6,CNTN1,TNIK,NKAIN3,NAV3,GPC5,MACF1,ADCY2,TNC,RYR3,PLCB1,NRG3,FAT3,FMN2,DTNA,KALRN,SYNE1,DGKG
3.016e-06	-12.71	lung-left_upper_lobe-carcinoma-adenocarcinoma	COSMIC cancer mutations	lung-left_upper_lobe-carcinoma-adenocarcinoma	556	10	16828	48	ADCY2,NAV3,SLC4A4,FAT3,RYR3,PLCB1,SYNE1,LRP1B,CTNND2,NTRK2
3.114e-06	-12.68	left_upper_lobe	COSMIC cancer mutations	left_upper_lobe	558	10	16828	48	NAV3,ADCY2,RYR3,PLCB1,FAT3,SLC4A4,SYNE1,CTNND2,LRP1B,NTRK2
3.175e-06	-12.66	cell development	biological process	GO:0048468	2236	19	18204	50	NTM,NTRK2,CTNND2,DCLK2,FMN2,NEBL,CNTN1,CTNNA2,FAT3,PARD3,NRXN1,TNIK,RORA,TNC,NRCAM,GPM6A,DGKG,KALRN,MSI2
3.302e-06	-12.62	brain development	biological process	GO:0007420	724	11	18204	50	NRCAM,SLC1A2,CTNNA2,CNTN1,NRG3,ATP1A2,RORA,DCLK2,NTRK2,PLCB1,RFX4
3.587e-06	-12.54	multicellular organismal process	biological process	GO:0032501	6177	33	18204	50	GPM6A,CAMK2G,DGKG,NRG3,KALRN,MSI2,TNIK,SLC4A4,RORA,TNC,CTNNA2,PARD3,LSAMP,ATP1A2,SOX5,CTNND2,DCLK2,NTRK2,ABLIM1,NRCAM,DTNA,NAV2,NRXN1,NEBL,SLC1A2,CNTN1,FAT3,RYR3,NTM,PLCB1,NAV3,SYNE1,RFX4
3.650e-06	-12.52	MAPT (microtubule associated protein tau)	protein interactions	4137	948	12	19454	50	ABLIM1,CTNNA2,CTNND2,NTM,SORBS1,ATP1A2,SLC1A2,LSAMP,NEBL,TNIK,GPM6A,MAPK10
3.952e-06	-12.44	neuron projection	cellular component	GO:0043005	1331	14	19108	49	GPM6A,PARD3,SYNE1,NRCAM,NTRK2,CNTN1,CTNNA2,CAMK2G,SLC1A2,CTNND2,ATP1A2,FAT3,ADCY2,DTNA
4.541e-06	-12.30	postsynapse	cellular component	GO:0098794	646	10	19108	49	CTNND2,KALRN,NRCAM,SYNE1,GPM6A,CNTN1,TNIK,NTRK2,ATP1A2,PLCB1
4.679e-06	-12.27	cell junction	cellular component	GO:0030054	2224	18	19108	49	CNTN1,CTNNA2,NRXN1,SLC1A2,KALRN,CTNND2,PLCB1,ATP1A2,DTNA,SORBS1,GPM6A,TNIK,PARD3,SYNE1,TNC,NRCAM,NRG3,NTRK2
5.753e-06	-12.07	skin-face-carcinoma-squamous_cell_carcinoma	COSMIC cancer mutations	skin-face-carcinoma-squamous_cell_carcinoma	2036	18	16828	48	SYNE1,PARD3,GPM6A,FMN2,MSI2,NAV2,TRPM3,RORA,LSAMP,MACF1,GPC5,NAV3,NRG3,NEBL,PLCB1,LRP1B,RBMS3,ABLIM1
6.057e-06	-12.01	neuron projection morphogenesis	biological process	GO:0048812	486	9	18204	50	CTNND2,TNIK,NRXN1,CTNNA2,GPM6A,CNTN1,NRCAM,PARD3,KALRN
6.254e-06	-11.98	head development	biological process	GO:0060322	774	11	18204	50	CTNNA2,CNTN1,NRCAM,SLC1A2,NRG3,RORA,NTRK2,DCLK2,ATP1A2,RFX4,PLCB1
6.387e-06	-11.96	intestinal_adenocarcinoma	COSMIC cancer mutations	intestinal_adenocarcinoma	7225	36	16828	48	HPSE2,SOX5,NRXN1,DCLK2,CNTN1,LRP1B,NRG3,FAT3,RYR3,PLCB1,TNC,ADCY2,MACF1,NAV3,DGKG,RFX4,SYNE1,KALRN,FMN2,NTM,SLC1A2,SLC4A4,PITPNC1,SLC14A1,NHSL1,SFXN5,CTNND2,NEBL,LSAMP,RORA,NRCAM,TRPM3,ATP1A2,NTRK2,PARD3,NAV2
6.387e-06	-11.96	stomach-carcinoma-intestinal_adenocarcinoma	COSMIC cancer mutations	stomach-carcinoma-intestinal_adenocarcinoma	7225	36	16828	48	SLC1A2,SLC4A4,SFXN5,CTNND2,PITPNC1,SLC14A1,NHSL1,LSAMP,RORA,NRCAM,NEBL,PARD3,NAV2,TRPM3,ATP1A2,NTRK2,SOX5,NRXN1,DCLK2,HPSE2,LRP1B,CNTN1,ADCY2,MACF1,NAV3,NRG3,FAT3,PLCB1,RYR3,TNC,RFX4,SYNE1,KALRN,FMN2,NTM,DGKG
6.578e-06	-11.93	plasma membrane bounded cell projection morphogenesis	biological process	GO:0120039	491	9	18204	50	NRCAM,CTNNA2,CNTN1,GPM6A,PARD3,KALRN,TNIK,NRXN1,CTNND2
7.138e-06	-11.85	cell projection morphogenesis	biological process	GO:0048858	496	9	18204	50	PARD3,KALRN,CTNNA2,GPM6A,CNTN1,NRCAM,CTNND2,TNIK,NRXN1
7.941e-06	-11.74	upper_aerodigestive_tract	COSMIC cancer mutations	upper_aerodigestive_tract	13181	48	16828	48	MGAT4C,NAV2,GPM6A,NEBL,NRCAM,RORA,LSAMP,NHSL1,SLC14A1,PITPNC1,ABLIM1,DGKG,MSI2,KALRN,SYNE1,RFX4,TNC,PLCB1,FAT3,NAV3,GPC5,MACF1,ADCY2,TNIK,LRP1B,RBMS3,CAMK2G,SOX5,NTRK2,ATP1A2,TRPM3,PARD3,CTNND2,SFXN5,SLC4A4,SLC1A2,SORBS1,NTM,DTNA,FMN2,RYR3,NRG3,NKAIN3,CNTN1,DPP6,HPSE2,DCLK2,NRXN1
8.691e-06	-11.65	trunk	COSMIC cancer mutations	trunk	3554	24	16828	48	RYR3,PLCB1,TNC,NRG3,FAT3,MACF1,DGKG,KALRN,SYNE1,HPSE2,NRXN1,DCLK2,SOX5,LRP1B,NEBL,NRCAM,LSAMP,ATP1A2,MGAT4C,NTRK2,PARD3,ABLIM1,SLC14A1,CTNND2
9.591e-06	-11.55	plasma membrane bounded cell projection organization	biological process	GO:0120036	1152	13	18204	50	KALRN,PARD3,ABLIM1,NRCAM,GPM6A,CNTN1,FAT3,CTNNA2,TNC,RFX4,NRXN1,TNIK,CTNND2
9.764e-06	-11.54	telencephalon development	biological process	GO:0021537	276	7	18204	50	NRG3,SLC1A2,PLCB1,RFX4,ATP1A2,NTRK2,DCLK2
1.140e-05	-11.38	carcinoid-endocrine_tumour	COSMIC cancer mutations	carcinoid-endocrine_tumour	7752	37	16828	48	SLC4A4,SLC1A2,ABLIM1,NHSL1,CTNND2,SFXN5,NEBL,RORA,LSAMP,NRCAM,TRPM3,NTRK2,ATP1A2,GPM6A,PARD3,NAV2,HPSE2,SOX5,DCLK2,CAMK2G,CNTN1,TNIK,LRP1B,DPP6,NRG3,TNC,RYR3,PLCB1,MACF1,GPC5,ADCY2,NKAIN3,DGKG,KALRN,SYNE1,RFX4,FMN2
1.156e-05	-11.37	face	COSMIC cancer mutations	face	2139	18	16828	48	TRPM3,SYNE1,GPM6A,PARD3,NAV2,MSI2,FMN2,NEBL,NRG3,PLCB1,MACF1,GPC5,RORA,LSAMP,NAV3,LRP1B,ABLIM1,RBMS3
1.209e-05	-11.32	nodular	COSMIC cancer mutations	nodular	1515	15	16828	48	CNTN1,CTNND2,LRP1B,ABLIM1,SLC4A4,DCLK2,ATP1A2,DGKG,NTRK2,SYNE1,KALRN,FMN2,NEBL,PLCB1,MACF1
1.272e-05	-11.27	synapse	cellular component	GO:0045202	1473	14	19108	49	NRXN1,SLC1A2,KALRN,CTNND2,NRCAM,GPM6A,TNIK,CNTN1,SYNE1,DTNA,NTRK2,PLCB1,NRG3,ATP1A2
1.338e-05	-11.22	kidney-carcinoma-papillary_renal_cell_carcinoma	COSMIC cancer mutations	kidney-carcinoma-papillary_renal_cell_carcinoma	6364	33	16828	48	TNIK,CNTN1,LRP1B,HPSE2,NRXN1,CAMK2G,DCLK2,SOX5,DGKG,FMN2,NTM,RFX4,KALRN,SYNE1,PLCB1,RYR3,NRG3,FAT3,NAV3,ADCY2,GPC5,MACF1,PITPNC1,CTNND2,ABLIM1,SLC4A4,ATP1A2,NTRK2,TRPM3,NAV2,PARD3,NRCAM,RORA
1.338e-05	-11.22	papillary_renal_cell_carcinoma	COSMIC cancer mutations	papillary_renal_cell_carcinoma	6364	33	16828	48	PITPNC1,CTNND2,SLC4A4,ABLIM1,TRPM3,NTRK2,ATP1A2,PARD3,NAV2,RORA,NRCAM,CNTN1,TNIK,LRP1B,HPSE2,SOX5,DCLK2,NRXN1,CAMK2G,DGKG,SYNE1,KALRN,RFX4,NTM,FMN2,NRG3,FAT3,RYR3,PLCB1,GPC5,MACF1,ADCY2,NAV3
1.353e-05	-11.21	C11orf52 (chromosome 11 open reading frame 52)	protein interactions	91894	310	7	19454	50	DTNA,ABLIM1,PARD3,TNIK,PLCB1,MACF1,FMN2
1.354e-05	-11.21	cell projection	cellular component	GO:0042995	2398	18	19108	49	NTRK2,GPM6A,PARD3,SYNE1,MACF1,NRCAM,ATP1A2,DTNA,FMN2,FAT3,ADCY2,CNTN1,ABLIM1,CTNNA2,NRXN1,SLC1A2,CAMK2G,CTNND2
1.370e-05	-11.20	plasma membrane region	cellular component	GO:0098590	1278	13	19108	49	CNTN1,SLC1A2,NRXN1,ATP1A2,SORBS1,MACF1,PARD3,SYNE1,GPM6A,TNIK,NRCAM,SLC4A4,SLC14A1
1.437e-05	-11.15	cell morphogenesis	biological process	GO:0000902	687	10	18204	50	CTNNA2,FAT3,CNTN1,GPM6A,NRCAM,PARD3,KALRN,CTNND2,TNIK,NRXN1
1.487e-05	-11.12	cell projection organization	biological process	GO:0030030	1200	13	18204	50	NRCAM,ABLIM1,GPM6A,KALRN,TNIK,NRXN1,TNC,FAT3,CTNNA2,CNTN1,PARD3,CTNND2,RFX4
1.562e-05	-11.07	lung-carcinoma-small_cell_carcinoma	COSMIC cancer mutations	lung-carcinoma-small_cell_carcinoma	9908	42	16828	48	NAV3,NKAIN3,GPC5,MACF1,RYR3,PLCB1,TNC,FAT3,NRG3,DTNA,FMN2,MSI2,NTM,RFX4,KALRN,SYNE1,DGKG,CAMK2G,NRXN1,DCLK2,SOX5,HPSE2,DPP6,LRP1B,TNIK,CNTN1,NRCAM,RORA,NEBL,NAV2,GPM6A,PARD3,ATP1A2,MGAT4C,NTRK2,TRPM3,SORBS1,ABLIM1,SLC4A4,CTNND2,SLC14A1,PITPNC1
1.569e-05	-11.06	right_upper_lobe	COSMIC cancer mutations	right_upper_lobe	10376	43	16828	48	DPP6,LRP1B,TNIK,CNTN1,NRXN1,DCLK2,SOX5,HPSE2,DTNA,FMN2,NTM,RFX4,SYNE1,KALRN,DGKG,NAV3,NKAIN3,ADCY2,MACF1,GPC5,RYR3,PLCB1,TNC,FAT3,NRG3,SFXN5,CTNND2,PITPNC1,SORBS1,SLC1A2,ABLIM1,SLC4A4,NAV2,GPM6A,PARD3,ATP1A2,MGAT4C,NTRK2,TRPM3,NRCAM,RORA,LSAMP,NEBL
1.569e-05	-11.06	lung-right_upper_lobe-carcinoma-adenocarcinoma	COSMIC cancer mutations	lung-right_upper_lobe-carcinoma-adenocarcinoma	10376	43	16828	48	NRCAM,LSAMP,RORA,NEBL,NAV2,GPM6A,MGAT4C,ABLIM1,PITPNC1,NAV3,MACF1,GPC5,ADCY2,TNC,PLCB1,FAT3,SYNE1,KALRN,RFX4,DGKG,SOX5,LRP1B,TNIK,PARD3,NTRK2,ATP1A2,TRPM3,SORBS1,SLC4A4,SLC1A2,CTNND2,SFXN5,NKAIN3,RYR3,NRG3,NTM,DTNA,FMN2,DCLK2,NRXN1,HPSE2,DPP6,CNTN1
1.589e-05	-11.05	small_cell_carcinoma	COSMIC cancer mutations	small_cell_carcinoma	9913	42	16828	48	DCLK2,NRXN1,CAMK2G,SOX5,HPSE2,LRP1B,DPP6,CNTN1,TNIK,NKAIN3,NAV3,MACF1,GPC5,TNC,RYR3,PLCB1,NRG3,FAT3,NTM,FMN2,MSI2,DTNA,KALRN,SYNE1,RFX4,DGKG,SORBS1,SLC4A4,ABLIM1,CTNND2,SLC14A1,PITPNC1,NRCAM,RORA,NEBL,NAV2,PARD3,GPM6A,NTRK2,MGAT4C,ATP1A2,TRPM3
1.776e-05	-10.94	tibia	COSMIC cancer mutations	tibia	836	11	16828	48	TRPM3,TNIK,LRP1B,CTNND2,GPM6A,ABLIM1,FAT3,PLCB1,MACF1,LSAMP,NKAIN3
1.850e-05	-10.90	FLOT1 (flotillin 1)	protein interactions	10211	453	8	19454	50	ABLIM1,DTNA,PARD3,SOX5,SORBS1,MACF1,SLC14A1,FMN2
1.892e-05	-10.88	oesophagus-carcinoma	COSMIC cancer mutations	oesophagus-carcinoma	4269	26	16828	48	CTNND2,NHSL1,SORBS1,SLC4A4,GPM6A,PARD3,TRPM3,NTRK2,NRCAM,DPP6,LRP1B,TNIK,CNTN1,SOX5,HPSE2,RFX4,KALRN,SYNE1,FMN2,NTM,ADCY2,MACF1,NAV3,NRG3,RYR3,PLCB1
2.057e-05	-10.79	autonomic_ganglia	COSMIC cancer mutations	autonomic_ganglia	4005	25	16828	48	ADCY2,MACF1,NAV3,NEBL,PLCB1,RYR3,TNC,RFX4,PARD3,KALRN,GPM6A,SYNE1,FMN2,NAV2,ATP1A2,NTRK2,DGKG,CAMK2G,SLC1A2,SLC4A4,LRP1B,CTNND2,PITPNC1,TNIK,NHSL1
2.126e-05	-10.76	oesophagus-carcinoma-squamous_cell_carcinoma	COSMIC cancer mutations	oesophagus-carcinoma-squamous_cell_carcinoma	6486	33	16828	48	NAV2,GPM6A,PARD3,ATP1A2,MGAT4C,TRPM3,NEBL,SFXN5,CTNND2,PITPNC1,SORBS1,ABLIM1,SLC4A4,FMN2,SYNE1,KALRN,NAV3,ADCY2,GPC5,MACF1,PLCB1,RYR3,TNC,FAT3,NRG3,DPP6,LRP1B,TNIK,CNTN1,NRXN1,DCLK2,SOX5,HPSE2
2.139e-05	-10.75	Nav/unc-53	interpro domains	IPR039041	3	2	18521	50	NAV3,NAV2
2.529e-05	-10.59	cell morphogenesis involved in neuron differentiation	biological process	GO:0048667	443	8	18204	50	KALRN,PARD3,NRCAM,CNTN1,FAT3,CTNNA2,NRXN1,CTNND2
2.562e-05	-10.57	membrane	cellular component	GO:0016020	9220	38	19108	49	NKAIN3,MACF1,PARD3,DGKG,TNC,SLC4A4,NRCAM,NRG3,NAV3,SLC14A1,CNTN1,HPSE2,NRXN1,CAMK2G,TRPM3,GPM6A,TNIK,MAPK10,NTM,SYNE1,LRP1B,GPC5,NTRK2,SFXN5,CTNNA2,SLC1A2,CTNND2,KALRN,RYR3,PLCB1,ATP1A2,DPP6,ADCY2,FMN2,DTNA,MGAT4C,SORBS1,LSAMP
2.673e-05	-10.53	breast-carcinoma-ductolobular_carcinoma	COSMIC cancer mutations	breast-carcinoma-ductolobular_carcinoma	1619	15	16828	48	NAV3,NRCAM,RORA,MACF1,PLCB1,DTNA,FMN2,SYNE1,KALRN,DGKG,SORBS1,ABLIM1,DPP6,CTNND2,CNTN1
2.673e-05	-10.53	ductolobular_carcinoma	COSMIC cancer mutations	ductolobular_carcinoma	1619	15	16828	48	SORBS1,ABLIM1,CTNND2,DPP6,CNTN1,NRCAM,NAV3,MACF1,RORA,PLCB1,FMN2,DTNA,SYNE1,KALRN,DGKG
2.933e-05	-10.44	plasma membrane bounded cell projection	cellular component	GO:0120025	2285	17	19108	49	CTNND2,CAMK2G,SLC1A2,CTNNA2,ABLIM1,CNTN1,FAT3,ADCY2,FMN2,DTNA,ATP1A2,NRCAM,MACF1,PARD3,SYNE1,GPM6A,NTRK2
3.423e-05	-10.28	CH	pfam domains	PF00307	67	4	17795	49	NAV2,SYNE1,MACF1,NAV3
3.600e-05	-10.23	Spectrin_repeat	interpro domains	IPR002017	24	3	18521	50	SYNE1,MACF1,KALRN
3.813e-05	-10.17	Spectrin	pfam domains	PF00435	24	3	17795	49	SYNE1,KALRN,MACF1
3.911e-05	-10.15	cell adhesion	biological process	GO:0007155	942	11	18204	50	CTNND2,LSAMP,NRXN1,NTM,SORBS1,TNC,FAT3,CTNNA2,CNTN1,NRCAM,PARD3
3.935e-05	-10.14	lymphoid_neoplasm	COSMIC cancer mutations	lymphoid_neoplasm	12233	46	16828	48	MGAT4C,NAV2,GPM6A,NEBL,NRCAM,RORA,LSAMP,NHSL1,PITPNC1,ABLIM1,DGKG,MSI2,KALRN,SYNE1,RFX4,TNC,PLCB1,FAT3,NAV3,GPC5,MACF1,ADCY2,TNIK,LRP1B,CAMK2G,SOX5,NTRK2,ATP1A2,TRPM3,PARD3,CTNND2,SFXN5,SLC4A4,SLC1A2,SORBS1,NTM,FMN2,DTNA,RYR3,NRG3,NKAIN3,CNTN1,DPP6,HPSE2,DCLK2,NRXN1
3.994e-05	-10.13	haematopoietic_and_lymphoid_tissue-lymph_node-lymphoid_neoplasm-diffuse_large_B_cell_lymphoma	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue-lymph_node-lymphoid_neoplasm-diffuse_large_B_cell_lymphoma	748	10	16828	48	NEBL,PLCB1,SOX5,NAV3,NTRK2,CTNND2,PARD3,LRP1B,SYNE1,DTNA
4.286e-05	-10.06	Ig_sub2	interpro domains	IPR003598	239	6	18521	50	NRCAM,NTRK2,CNTN1,KALRN,NTM,LSAMP
4.550e-05	-10.00	Htt (huntingtin)	protein interactions	15194	77	4	19454	50	LSAMP,GPM6A,CNTN1,NTM
4.839e-05	-9.94	superficial_spreading	COSMIC cancer mutations	superficial_spreading	1110	12	16828	48	TNC,PLCB1,MACF1,ADCY2,MGAT4C,NTM,KALRN,SYNE1,SLC4A4,SORBS1,CTNND2,LRP1B
5.229e-05	-9.86	anatomical structure morphogenesis	biological process	GO:0009653	2225	17	18204	50	NRCAM,ABLIM1,GPM6A,NRG3,KALRN,TNIK,NRXN1,RORA,TNC,NEBL,CTNNA2,FAT3,CNTN1,PARD3,SOX5,NTRK2,CTNND2
5.822e-05	-9.75	skin-trunk-malignant_melanoma	COSMIC cancer mutations	skin-trunk-malignant_melanoma	2647	19	16828	48	NEBL,NRG3,FAT3,TNC,PLCB1,RYR3,LSAMP,NRCAM,MGAT4C,ATP1A2,SYNE1,KALRN,PARD3,HPSE2,SOX5,NRXN1,SLC14A1,LRP1B,CTNND2
6.014e-05	-9.72	NS-malignant_melanoma	COSMIC cancer mutations	NS-malignant_melanoma	3420	22	16828	48	NEBL,PARD3,NAV2,TRPM3,MGAT4C,ATP1A2,CTNND2,PITPNC1,MACF1,GPC5,ADCY2,NRG3,TNC,PLCB1,KALRN,SYNE1,RFX4,FMN2,DGKG,NRXN1,LRP1B,DPP6
6.112e-05	-9.70	autonomic_ganglia-neuroblastoma	COSMIC cancer mutations	autonomic_ganglia-neuroblastoma	3970	24	16828	48	NAV2,FMN2,KALRN,PARD3,GPM6A,SYNE1,RFX4,DGKG,NTRK2,ATP1A2,NAV3,MACF1,ADCY2,TNC,PLCB1,RYR3,NEBL,LRP1B,CTNND2,TNIK,PITPNC1,CAMK2G,SLC4A4,SLC1A2
6.138e-05	-9.70	neuroblastoma	COSMIC cancer mutations	neuroblastoma	3971	24	16828	48	PARD3,GPM6A,NAV2,ATP1A2,NTRK2,NEBL,CTNND2,PITPNC1,SLC1A2,SLC4A4,RFX4,SYNE1,KALRN,FMN2,DGKG,ADCY2,MACF1,NAV3,RYR3,PLCB1,TNC,LRP1B,TNIK,CAMK2G
6.709e-05	-9.61	CH_dom	interpro domains	IPR001715	81	4	18521	50	SYNE1,MACF1,NAV3,NAV2
7.039e-05	-9.56	CH_dom_sf	interpro domains	IPR036872	82	4	18521	50	SYNE1,MACF1,NAV3,NAV2
7.140e-05	-9.55	Spectrin/alpha-actinin	interpro domains	IPR018159	30	3	18521	50	MACF1,SYNE1,KALRN
7.693e-05	-9.47	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-follicular_lymphoma	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-follicular_lymphoma	981	11	16828	48	HPSE2,SOX5,LRP1B,CTNND2,NRG3,NKAIN3,GPC5,ADCY2,LSAMP,RORA,PARD3
8.255e-05	-9.40	NTM (neurotrimin)	protein interactions	50863	33	3	19454	50	LSAMP,GPM6A,NTM
8.676e-05	-9.35	CH	smart domains	SM00033	66	4	9717	35	NAV3,SYNE1,NAV2,MACF1
9.194e-05	-9.29	cell junction organization	biological process	GO:0034330	532	8	18204	50	NRXN1,CTNND2,TNC,SORBS1,NRCAM,GPM6A,NRG3,PARD3
9.391e-05	-9.27	adrenal_cortical_carcinoma	COSMIC cancer mutations	adrenal_cortical_carcinoma	2256	17	16828	48	SLC1A2,HPSE2,SOX5,CNTN1,NHSL1,LRP1B,CTNND2,NRG3,TNC,NRCAM,TRPM3,ATP1A2,DGKG,NTRK2,RFX4,SYNE1,FMN2
9.463e-05	-9.27	Calponin-like domain	gene3d domains	1.10.418.10	79	4	14470	44	SYNE1,NAV2,MACF1,NAV3
9.610e-05	-9.25	pancreas-carcinoma-adenocarcinoma	COSMIC cancer mutations	pancreas-carcinoma-adenocarcinoma	517	8	16828	48	HPSE2,NEBL,TNC,GPC5,MACF1,DCLK2,LRP1B,SYNE1
9.811e-05	-9.23	skin-scalp-carcinoma-squamous_cell_carcinoma	COSMIC cancer mutations	skin-scalp-carcinoma-squamous_cell_carcinoma	1596	14	16828	48	SYNE1,ATP1A2,NRCAM,NAV3,MACF1,GPC5,RORA,LSAMP,PLCB1,CNTN1,RBMS3,NRXN1,SOX5,SLC4A4
1.006e-04	-9.20	Gastric acid secretion	KEGG pathways	hsa04971	75	4	7161	24	CAMK2G,ADCY2,ATP1A2,PLCB1
1.006e-04	-9.20	Gastric acid secretion	KEGG pathways	ko04971	75	4	7161	24	ATP1A2,ADCY2,CAMK2G,PLCB1
1.038e-04	-9.17	diffuse_adenocarcinoma	COSMIC cancer mutations	diffuse_adenocarcinoma	4383	25	16828	48	FAT3,NRG3,TNC,RYR3,MACF1,ADCY2,DGKG,SYNE1,KALRN,RFX4,FMN2,DTNA,SOX5,CNTN1,LRP1B,DPP6,TRPM3,MGAT4C,ATP1A2,GPM6A,PARD3,NAV2,ABLIM1,NHSL1,CTNND2
1.038e-04	-9.17	stomach-carcinoma-diffuse_adenocarcinoma	COSMIC cancer mutations	stomach-carcinoma-diffuse_adenocarcinoma	4383	25	16828	48	PARD3,GPM6A,NAV2,TRPM3,MGAT4C,ATP1A2,ABLIM1,CTNND2,NHSL1,MACF1,ADCY2,NRG3,FAT3,TNC,RYR3,KALRN,SYNE1,RFX4,FMN2,DTNA,DGKG,SOX5,LRP1B,DPP6,CNTN1
1.074e-04	-9.14	PTPRB (protein tyrosine phosphatase receptor type B)	protein interactions	5787	36	3	19454	50	CNTN1,NRCAM,TNC
1.104e-04	-9.11	follicular_lymphoma	COSMIC cancer mutations	follicular_lymphoma	1209	12	16828	48	CTNND2,LRP1B,TNIK,SOX5,HPSE2,PARD3,NKAIN3,GPC5,LSAMP,ADCY2,RORA,NRG3
1.166e-04	-9.06	CDH1 (cadherin 1)	protein interactions	999	757	9	19454	50	MACF1,CTNND2,SORBS1,PARD3,NEBL,ABLIM1,NHSL1,CTNNA2,NAV2
1.167e-04	-9.06	DNAAF2 (dynein axonemal assembly factor 2)	protein interactions	55172	98	4	19454	50	DPP6,GPM6A,LSAMP,CNTN1
1.174e-04	-9.05	forebrain development	biological process	GO:0030900	408	7	18204	50	ATP1A2,SLC1A2,DCLK2,NTRK2,NRG3,PLCB1,RFX4
1.245e-04	-8.99	cell junction assembly	biological process	GO:0034329	285	6	18204	50	GPM6A,NRCAM,NRXN1,PARD3,SORBS1,NRG3
1.370e-04	-8.90	actin binding	molecular function	GO:0003779	434	7	18094	48	SORBS1,ABLIM1,SYNE1,FMN2,MACF1,NEBL,CTNNA2
1.380e-04	-8.89	CH	prosite domains	PS50021	81	4	12186	40	NAV2,NAV3,MACF1,SYNE1
1.404e-04	-8.87	axon development	biological process	GO:0061564	420	7	18204	50	NRCAM,NRXN1,CTNNA2,CNTN1,TNC,PARD3,KALRN
1.461e-04	-8.83	skin-extremity-malignant_melanoma	COSMIC cancer mutations	skin-extremity-malignant_melanoma	1875	15	16828	48	PITPNC1,DPP6,LRP1B,HPSE2,DGKG,NTRK2,PARD3,SYNE1,FMN2,NEBL,RYR3,PLCB1,TNC,ADCY2,NAV3
1.467e-04	-8.83	SPEC	smart domains	SM00150	29	3	9717	35	KALRN,MACF1,SYNE1
1.470e-04	-8.83	extremity	COSMIC cancer mutations	extremity	1876	15	16828	48	PLCB1,RYR3,TNC,NEBL,NAV3,ADCY2,NTRK2,DGKG,FMN2,SYNE1,PARD3,HPSE2,PITPNC1,DPP6,LRP1B
1.476e-04	-8.82	DZIP1 (DAZ interacting zinc finger protein 1)	protein interactions	22873	40	3	19454	50	PARD3,CAMK2G,NTRK2
1.531e-04	-8.78	LCK (LCK proto-oncogene, Src family tyrosine kinase)	protein interactions	3932	455	7	19454	50	MACF1,KALRN,FMN2,CAMK2G,DTNA,PARD3,CTNND2
1.558e-04	-8.77	urinary_tract-bladder-carcinoma-transitional_cell_carcinoma	COSMIC cancer mutations	urinary_tract-bladder-carcinoma-transitional_cell_carcinoma	6040	30	16828	48	FMN2,DTNA,KALRN,SYNE1,RFX4,DGKG,NAV3,GPC5,MACF1,ADCY2,TNC,PLCB1,NRG3,LRP1B,NRXN1,CAMK2G,HPSE2,NAV2,PARD3,GPM6A,MGAT4C,NTRK2,ATP1A2,TRPM3,NRCAM,NEBL,SFXN5,SORBS1,SLC4A4,ABLIM1
1.560e-04	-8.77	haematopoietic_neoplasm	COSMIC cancer mutations	haematopoietic_neoplasm	11082	43	16828	48	TNIK,CNTN1,LRP1B,DPP6,HPSE2,DCLK2,RBMS3,CAMK2G,NRXN1,SOX5,DGKG,NTM,MSI2,FMN2,DTNA,KALRN,SYNE1,RFX4,TNC,PLCB1,RYR3,NRG3,FAT3,NKAIN3,NAV3,GPC5,MACF1,ADCY2,SLC14A1,NHSL1,CTNND2,SFXN5,SLC4A4,ABLIM1,SLC1A2,NTRK2,ATP1A2,TRPM3,NAV2,PARD3,NEBL,RORA,LSAMP
1.569e-04	-8.76	transitional_cell_carcinoma	COSMIC cancer mutations	transitional_cell_carcinoma	6042	30	16828	48	HPSE2,NRXN1,CAMK2G,LRP1B,PLCB1,TNC,NRG3,NAV3,ADCY2,MACF1,GPC5,DGKG,FMN2,DTNA,RFX4,KALRN,SYNE1,ABLIM1,SLC4A4,SORBS1,SFXN5,NEBL,NRCAM,ATP1A2,MGAT4C,NTRK2,TRPM3,NAV2,GPM6A,PARD3
1.604e-04	-8.74	-	gene3d domains	1.20.58.60	35	3	14470	44	MACF1,KALRN,SYNE1
1.626e-04	-8.72	regulation of dendrite development	biological process	GO:0050773	100	4	18204	50	TNIK,FAT3,DGKG,SYNE1
1.627e-04	-8.72	TIAM1 (TIAM Rac1 associated GEF 1)	protein interactions	7074	201	5	19454	50	CAMK2G,DTNA,ATP1A2,PARD3,RYR3
1.639e-04	-8.72	Insulin secretion	KEGG pathways	hsa04911	85	4	7161	24	CAMK2G,ATP1A2,ADCY2,PLCB1
1.829e-04	-8.61	Neurofascin interactions	REACTOME pathways	R-HSA-447043	7	2	10285	31	NRCAM,CNTN1
1.834e-04	-8.60	C2CD4B (C2 calcium dependent domain containing 4B)	protein interactions	388125	43	3	19454	50	LRP1B,FAT3,MACF1
1.855e-04	-8.59	IGc2	smart domains	SM00408	239	6	9717	35	KALRN,NTRK2,NRCAM,NTM,LSAMP,CNTN1
1.865e-04	-8.59	adrenal_gland	COSMIC cancer mutations	adrenal_gland	2628	18	16828	48	SYNE1,RFX4,FMN2,TRPM3,DGKG,NTRK2,ATP1A2,ADCY2,NRCAM,NRG3,TNC,CTNND2,LRP1B,NHSL1,CNTN1,SOX5,HPSE2,SLC1A2
1.907e-04	-8.56	upper_aerodigestive_tract-pharynx-carcinoma-squamous_cell_carcinoma	COSMIC cancer mutations	upper_aerodigestive_tract-pharynx-carcinoma-squamous_cell_carcinoma	1485	13	16828	48	SLC14A1,LRP1B,DPP6,SORBS1,DGKG,SYNE1,FMN2,DTNA,NRG3,RYR3,MACF1,GPC5,NRCAM
2.046e-04	-8.49	Salivary secretion	KEGG pathways	ko04970	90	4	7161	24	PLCB1,RYR3,ADCY2,ATP1A2
2.046e-04	-8.49	Salivary secretion	KEGG pathways	hsa04970	90	4	7161	24	PLCB1,ATP1A2,ADCY2,RYR3
2.053e-04	-8.49	skin-trunk-malignant_melanoma-nodular	COSMIC cancer mutations	skin-trunk-malignant_melanoma-nodular	1291	12	16828	48	DCLK2,ABLIM1,LRP1B,CTNND2,MACF1,NEBL,PLCB1,KALRN,SYNE1,DGKG,NTRK2,ATP1A2
2.209e-04	-8.42	acral_lentiginous	COSMIC cancer mutations	acral_lentiginous	745	9	16828	48	PARD3,LRP1B,KALRN,SYNE1,NAV3,MACF1,PLCB1,TNC,NRG3
2.225e-04	-8.41	cytoskeletal protein binding	molecular function	GO:0008092	989	10	18094	48	FMN2,MACF1,NRCAM,NAV3,NEBL,CTNNA2,SORBS1,ABLIM1,SYNE1,DCLK2
2.227e-04	-8.41	GnRH signaling pathway	KEGG pathways	ko04912	92	4	7161	24	PLCB1,CAMK2G,MAPK10,ADCY2
2.227e-04	-8.41	GnRH signaling pathway	KEGG pathways	hsa04912	92	4	7161	24	PLCB1,MAPK10,CAMK2G,ADCY2
2.255e-04	-8.40	central_nervous_system-cerebellum-glioma-astrocytoma_Grade_I	COSMIC cancer mutations	central_nervous_system-cerebellum-glioma-astrocytoma_Grade_I	105	4	16828	48	PARD3,LRP1B,GPC5,NRG3
2.257e-04	-8.40	axon	cellular component	GO:0030424	650	8	19108	49	GPM6A,CNTN1,CTNNA2,PARD3,SLC1A2,DTNA,NTRK2,NRCAM
2.284e-04	-8.38	skin-head_neck-malignant_melanoma-superficial_spreading	COSMIC cancer mutations	skin-head_neck-malignant_melanoma-superficial_spreading	923	10	16828	48	MGAT4C,KALRN,CTNND2,SYNE1,LRP1B,TNC,PLCB1,SORBS1,MACF1,ADCY2
2.304e-04	-8.38	NEGR1 (neuronal growth regulator 1)	protein interactions	257194	9	2	19454	50	LSAMP,NTM
2.304e-04	-8.38	LSAMP (limbic system associated membrane protein)	protein interactions	4045	9	2	19454	50	NTM,LSAMP
2.342e-04	-8.36	actin filament binding	molecular function	GO:0051015	211	5	18094	48	MACF1,ABLIM1,NEBL,SYNE1,CTNNA2
2.392e-04	-8.34	CNTN1 (contactin 1)	protein interactions	1272	47	3	19454	50	TNC,GPM6A,CNTN1
2.520e-04	-8.29	Pancreatic secretion	KEGG pathways	ko04972	95	4	7161	24	ATP1A2,ADCY2,SLC4A4,PLCB1
2.520e-04	-8.29	Pancreatic secretion	KEGG pathways	hsa04972	95	4	7161	24	ATP1A2,ADCY2,SLC4A4,PLCB1
2.544e-04	-8.28	adenoid_cystic_carcinoma	COSMIC cancer mutations	adenoid_cystic_carcinoma	1123	11	16828	48	CAMK2G,NRCAM,RORA,RYR3,NAV2,SYNE1,LRP1B,CTNND2,TNIK,NTRK2,MGAT4C
2.564e-04	-8.27	OCLN (occludin)	protein interactions	100506658	495	7	19454	50	PARD3,FMN2,MACF1,NTRK2,TNIK,DTNA,ABLIM1
2.586e-04	-8.26	cellular response to organic cyclic compound	biological process	GO:0071407	464	7	18204	50	PLCB1,TNC,RORA,ATP1A2,RYR3,SLC1A2,ADCY2
2.624e-04	-8.25	Circadian entrainment	KEGG pathways	hsa04713	96	4	7161	24	CAMK2G,RYR3,ADCY2,PLCB1
2.624e-04	-8.25	Circadian entrainment	KEGG pathways	ko04713	96	4	7161	24	PLCB1,RYR3,CAMK2G,ADCY2
2.731e-04	-8.21	Inflammatory mediator regulation of TRP channels	KEGG pathways	hsa04750	97	4	7161	24	CAMK2G,MAPK10,ADCY2,PLCB1
2.731e-04	-8.21	Inflammatory mediator regulation of TRP channels	KEGG pathways	ko04750	97	4	7161	24	CAMK2G,MAPK10,ADCY2,PLCB1
2.876e-04	-8.15	salivary_gland	COSMIC cancer mutations	salivary_gland	1139	11	16828	48	TNIK,CTNND2,LRP1B,CAMK2G,MGAT4C,NTRK2,NAV2,SYNE1,RYR3,NRCAM,RORA
2.879e-04	-8.15	pancreas-carcinoid-endocrine_tumour	COSMIC cancer mutations	pancreas-carcinoid-endocrine_tumour	7250	33	16828	48	GPM6A,PARD3,NAV2,ATP1A2,NTRK2,RORA,LSAMP,NRCAM,NEBL,SFXN5,CTNND2,NHSL1,SLC1A2,ABLIM1,SLC4A4,RFX4,KALRN,SYNE1,FMN2,DGKG,ADCY2,MACF1,GPC5,NKAIN3,NRG3,PLCB1,RYR3,TNC,DPP6,LRP1B,CNTN1,SOX5,HPSE2
2.889e-04	-8.15	synapse organization	biological process	GO:0050808	333	6	18204	50	GPM6A,NRCAM,NRG3,CTNND2,NRXN1,TNC
2.906e-04	-8.14	mixed_intestinal_and_diffuse_adenocarcinoma-unclassifiable	COSMIC cancer mutations	mixed_intestinal_and_diffuse_adenocarcinoma-unclassifiable	951	10	16828	48	SLC1A2,TNC,GPC5,MACF1,TRPM3,CNTN1,SYNE1,LRP1B,PARD3,FMN2
2.906e-04	-8.14	stomach-carcinoma-mixed_intestinal_and_diffuse_adenocarcinoma-unclassifiable	COSMIC cancer mutations	stomach-carcinoma-mixed_intestinal_and_diffuse_adenocarcinoma-unclassifiable	951	10	16828	48	SLC1A2,TNC,GPC5,MACF1,TRPM3,CNTN1,PARD3,SYNE1,LRP1B,FMN2
3.069e-04	-8.09	synapse assembly	biological process	GO:0007416	118	4	18204	50	NRXN1,NRCAM,GPM6A,NRG3
3.150e-04	-8.06	skin-mucosal-malignant_melanoma	COSMIC cancer mutations	skin-mucosal-malignant_melanoma	2009	15	16828	48	ABLIM1,SORBS1,LRP1B,CTNND2,TNC,PLCB1,NEBL,NRG3,RORA,MGAT4C,ATP1A2,NAV2,FMN2,PARD3,SYNE1
3.150e-04	-8.06	mucosal	COSMIC cancer mutations	mucosal	2009	15	16828	48	SORBS1,ABLIM1,CTNND2,LRP1B,RORA,PLCB1,TNC,NRG3,NEBL,FMN2,NAV2,PARD3,SYNE1,ATP1A2,MGAT4C
3.162e-04	-8.06	EPB41L4A (erythrocyte membrane protein band 4.1 like 4A)	protein interactions	64097	127	4	19454	50	DTNA,ABLIM1,MACF1,PARD3
3.285e-04	-8.02	acute_myeloid_leukaemia	COSMIC cancer mutations	acute_myeloid_leukaemia	10418	41	16828	48	SLC14A1,NHSL1,SFXN5,CTNND2,SLC1A2,ABLIM1,SLC4A4,ATP1A2,NTRK2,TRPM3,NAV2,PARD3,NEBL,LSAMP,RORA,CNTN1,TNIK,DPP6,LRP1B,HPSE2,CAMK2G,NRXN1,RBMS3,SOX5,DGKG,MSI2,FMN2,NTM,RFX4,SYNE1,KALRN,PLCB1,RYR3,TNC,FAT3,NRG3,NAV3,NKAIN3,ADCY2,GPC5,MACF1
3.285e-04	-8.02	haematopoietic_and_lymphoid_tissue-haematopoietic_neoplasm-acute_myeloid_leukaemia	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue-haematopoietic_neoplasm-acute_myeloid_leukaemia	10418	41	16828	48	PARD3,NAV2,TRPM3,NTRK2,ATP1A2,RORA,LSAMP,NEBL,CTNND2,SFXN5,NHSL1,SLC14A1,SLC4A4,SLC1A2,ABLIM1,KALRN,SYNE1,RFX4,NTM,FMN2,MSI2,DGKG,MACF1,GPC5,ADCY2,NKAIN3,NAV3,FAT3,NRG3,TNC,PLCB1,RYR3,LRP1B,DPP6,TNIK,CNTN1,SOX5,RBMS3,CAMK2G,NRXN1,HPSE2
3.290e-04	-8.02	stomach-adenocarcinoma	COSMIC cancer mutations	stomach-adenocarcinoma	4101	23	16828	48	NEBL,NRG3,TNC,PLCB1,GPC5,MACF1,RORA,NRCAM,NAV3,MGAT4C,ATP1A2,SYNE1,KALRN,PARD3,RFX4,NAV2,FMN2,SLC4A4,SLC1A2,ABLIM1,CNTN1,LRP1B,CTNND2
3.387e-04	-7.99	actin cytoskeleton	cellular component	GO:0015629	520	7	19108	49	SORBS1,FMN2,CTNNA2,MACF1,ABLIM1,KALRN,NEBL
3.423e-04	-7.98	animal organ development	biological process	GO:0048513	2846	18	18204	50	ATP1A2,SOX5,DCLK2,NTRK2,PLCB1,SYNE1,RFX4,SLC1A2,NEBL,CTNNA2,FAT3,CNTN1,RORA,TNC,NRCAM,ABLIM1,GPM6A,NRG3
3.432e-04	-7.98	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm	7307	33	16828	48	MGAT4C,NTRK2,GPM6A,PARD3,NAV2,NEBL,RORA,LSAMP,NHSL1,SFXN5,CTNND2,ABLIM1,SLC1A2,DGKG,RFX4,KALRN,SYNE1,FMN2,NRG3,RYR3,PLCB1,TNC,ADCY2,GPC5,MACF1,NAV3,NKAIN3,TNIK,CNTN1,DPP6,LRP1B,HPSE2,SOX5
3.491e-04	-7.96	interstitial matrix	cellular component	GO:0005614	11	2	19108	49	NAV2,TNC
3.669e-04	-7.91	YWHAH (tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein eta)	protein interactions	7533	1083	10	19454	50	PITPNC1,DCLK2,MACF1,FMN2,ABLIM1,NAV2,NHSL1,CAMK2G,SORBS1,PARD3
3.702e-04	-7.90	EZR (ezrin)	protein interactions	7430	526	7	19454	50	MAPK10,NEBL,SORBS1,MACF1,DTNA,ABLIM1,TNIK
3.713e-04	-7.90	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-NK-T_cell_lymphoma	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-NK-T_cell_lymphoma	217	5	16828	48	RFX4,NAV2,DTNA,MGAT4C,PLCB1
3.863e-04	-7.86	skin-scalp-malignant_melanoma	COSMIC cancer mutations	skin-scalp-malignant_melanoma	634	8	16828	48	SORBS1,CAMK2G,NEBL,TNC,PLCB1,SYNE1,NTM,FMN2
3.954e-04	-7.84	EGF-like_dom	interpro domains	IPR000742	232	5	18521	50	FAT3,TNC,NRXN1,LRP1B,NRG3
3.988e-04	-7.83	NTRK2 (neurotrophic receptor tyrosine kinase 2)	protein interactions	4915	135	4	19454	50	PARD3,ABLIM1,DTNA,NTRK2
4.260e-04	-7.76	EGF_3	prosite domains	PS50026	196	5	12186	40	NRXN1,NRG3,TNC,FAT3,LRP1B
4.301e-04	-7.75	LYN (LYN proto-oncogene, Src family tyrosine kinase)	protein interactions	4067	713	8	19454	50	TNIK,PLCB1,MACF1,FMN2,DTNA,ABLIM1,MSI2,PARD3
4.382e-04	-7.73	NK-T_cell_lymphoma	COSMIC cancer mutations	NK-T_cell_lymphoma	225	5	16828	48	PLCB1,MGAT4C,RFX4,DTNA,NAV2
4.599e-04	-7.68	gallbladder	COSMIC cancer mutations	gallbladder	2821	18	16828	48	TRPM3,FMN2,SYNE1,PARD3,RYR3,TNC,FAT3,NRG3,NKAIN3,NRCAM,MACF1,TNIK,NHSL1,PITPNC1,DPP6,CTNND2,LRP1B,SLC4A4
4.599e-04	-7.68	biliary_tract-gallbladder-carcinoma-adenocarcinoma	COSMIC cancer mutations	biliary_tract-gallbladder-carcinoma-adenocarcinoma	2821	18	16828	48	FMN2,PARD3,SYNE1,TRPM3,NKAIN3,NRCAM,MACF1,RYR3,TNC,NRG3,FAT3,DPP6,LRP1B,CTNND2,TNIK,NHSL1,PITPNC1,SLC4A4
4.776e-04	-7.65	axonogenesis	biological process	GO:0007409	366	6	18204	50	KALRN,PARD3,CNTN1,CTNNA2,NRXN1,NRCAM
5.017e-04	-7.60	haematopoietic_and_lymphoid_tissue	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue	14368	48	16828	48	NKAIN3,RYR3,NRG3,FMN2,DTNA,NTM,NRXN1,DCLK2,HPSE2,DPP6,CNTN1,PARD3,ATP1A2,NTRK2,TRPM3,SORBS1,SLC1A2,SLC4A4,SFXN5,CTNND2,NAV3,ADCY2,GPC5,MACF1,PLCB1,TNC,FAT3,MSI2,RFX4,KALRN,SYNE1,DGKG,CAMK2G,RBMS3,SOX5,LRP1B,TNIK,NRCAM,LSAMP,RORA,NEBL,NAV2,GPM6A,MGAT4C,ABLIM1,SLC14A1,NHSL1,PITPNC1
5.099e-04	-7.58	upper_aerodigestive_tract-pharynx-carcinoma-nasopharyngeal_carcinoma	COSMIC cancer mutations	upper_aerodigestive_tract-pharynx-carcinoma-nasopharyngeal_carcinoma	1425	12	16828	48	FAT3,FMN2,SYNE1,RFX4,NTRK2,ATP1A2,SLC4A4,SLC1A2,CTNND2,SFXN5,NHSL1,PITPNC1
5.099e-04	-7.58	nasopharyngeal_carcinoma	COSMIC cancer mutations	nasopharyngeal_carcinoma	1425	12	16828	48	FAT3,NTRK2,ATP1A2,SYNE1,RFX4,FMN2,SLC4A4,SLC1A2,PITPNC1,NHSL1,CTNND2,SFXN5
5.297e-04	-7.54	synaptic membrane	cellular component	GO:0097060	400	6	19108	49	NRCAM,SLC1A2,NRXN1,SYNE1,GPM6A,CNTN1
5.297e-04	-7.54	fn3	pfam domains	PF00041	136	4	17795	49	CNTN1,KALRN,NRCAM,TNC
5.583e-04	-7.49	regulation of synapse organization	biological process	GO:0050807	246	5	18204	50	CTNNA2,GPM6A,NTRK2,NRCAM,NRXN1
5.605e-04	-7.49	hairy_cell_leukaemia	COSMIC cancer mutations	hairy_cell_leukaemia	1440	12	16828	48	NRXN1,CTNND2,LRP1B,CNTN1,NAV3,MACF1,RYR3,NEBL,NAV2,FMN2,SYNE1,RFX4
5.605e-04	-7.49	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-hairy_cell_leukaemia	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-hairy_cell_leukaemia	1440	12	16828	48	SYNE1,RFX4,NAV2,FMN2,MACF1,NAV3,NEBL,RYR3,CTNND2,LRP1B,CNTN1,NRXN1
5.774e-04	-7.46	adenoma	COSMIC cancer mutations	adenoma	2873	18	16828	48	ADCY2,MACF1,GPC5,NAV3,NEBL,RYR3,TNC,GPM6A,SYNE1,KALRN,PARD3,TRPM3,NTRK2,SOX5,DCLK2,HPSE2,LRP1B,CTNND2
5.879e-04	-7.44	Laminin	gene3d domains	2.10.25.10	226	5	14470	44	NRXN1,FAT3,NRG3,LRP1B,TNC
5.976e-04	-7.42	transmission of nerve impulse	biological process	GO:0019226	60	3	18204	50	NRCAM,ATP1A2,NTRK2
6.009e-04	-7.42	regulation of cellular component organization	biological process	GO:0051128	2455	16	18204	50	CTNNA2,FAT3,CNTN1,SYNE1,NAV3,PLCB1,NTRK2,NRG3,DGKG,CAMK2G,GPM6A,NRCAM,TNC,MACF1,TNIK,NRXN1
6.017e-04	-7.42	cell communication	biological process	GO:0007154	5010	25	18204	50	RYR3,ADCY2,MAPK10,SLC1A2,CNTN1,PLCB1,FMN2,NRCAM,DTNA,NRXN1,PARD3,PITPNC1,SORBS1,ATP1A2,DCLK2,CTNND2,NTRK2,NRG3,KALRN,DGKG,CAMK2G,TNC,TNIK,RORA,MACF1
6.069e-04	-7.41	Ig_3	pfam domains	PF13927	141	4	17795	49	NRCAM,LSAMP,NTM,CNTN1
6.169e-04	-7.39	Ion homeostasis	REACTOME pathways	R-HSA-5578775	56	3	10285	31	CAMK2G,RYR3,ATP1A2
6.187e-04	-7.39	glutamatergic synapse	cellular component	GO:0098978	412	6	19108	49	SLC1A2,NRCAM,TNIK,GPM6A,NRG3,PLCB1
6.187e-04	-7.39	neuron migration	biological process	GO:0001764	142	4	18204	50	NRCAM,NTRK2,GPM6A,FAT3
6.227e-04	-7.38	regulation of synapse structure or activity	biological process	GO:0050803	252	5	18204	50	CTNNA2,GPM6A,NTRK2,NRCAM,NRXN1
6.409e-04	-7.35	EF-hand-dom_pair	interpro domains	IPR011992	258	5	18521	50	DGKG,PLCB1,RYR3,DTNA,MACF1
6.412e-04	-7.35	cell adhesion molecule binding	molecular function	GO:0050839	560	7	18094	48	CNTN1,NRXN1,TNC,CTNNA2,NRCAM,MACF1,CTNND2
6.429e-04	-7.35	Ig_sub	interpro domains	IPR003599	394	6	18521	50	CNTN1,NRCAM,NTRK2,LSAMP,NTM,KALRN
6.451e-04	-7.35	kidney-other-neoplasm	COSMIC cancer mutations	kidney-other-neoplasm	10653	41	16828	48	TNC,RYR3,PLCB1,FAT3,NRG3,NKAIN3,NAV3,GPC5,MACF1,ADCY2,DGKG,DTNA,FMN2,SYNE1,KALRN,RFX4,HPSE2,CAMK2G,NRXN1,SOX5,TNIK,CNTN1,LRP1B,DPP6,NEBL,NRCAM,LSAMP,RORA,NTRK2,MGAT4C,ATP1A2,TRPM3,NAV2,PARD3,GPM6A,SLC1A2,ABLIM1,SORBS1,NHSL1,CTNND2,SFXN5
6.513e-04	-7.34	Cell-type Dependent Selectivity of CCK2R Signaling	WikiPathways	WP3679	13	2	5310	16	PLCB1,RYR3
6.544e-04	-7.33	astrocytoma_Grade_I	COSMIC cancer mutations	astrocytoma_Grade_I	139	4	16828	48	NRG3,PARD3,GPC5,LRP1B
6.557e-04	-7.33	soft_tissue	COSMIC cancer mutations	soft_tissue	5828	28	16828	48	MACF1,GPC5,ADCY2,NKAIN3,FAT3,NRG3,TNC,RYR3,PLCB1,SYNE1,FMN2,SOX5,CAMK2G,HPSE2,LRP1B,DPP6,RORA,LSAMP,NEBL,GPM6A,PARD3,NAV2,TRPM3,NTRK2,SORBS1,SLC1A2,CTNND2,NHSL1
6.588e-04	-7.33	sodium ion export across plasma membrane	biological process	GO:0036376	14	2	18204	50	ATP1A2,SLC4A4
6.654e-04	-7.32	TIAM2 (TIAM Rac1 associated GEF 2)	protein interactions	26230	15	2	19454	50	PARD3,TNIK
6.868e-04	-7.28	Transmembrane transport of small molecules	REACTOME pathways	R-HSA-382551	677	8	10285	31	RYR3,ADCY2,SLC4A4,ATP1A2,CAMK2G,SLC1A2,TRPM3,SLC14A1
6.979e-04	-7.27	central_nervous_system-cerebrum-glioma-astrocytoma_Grade_IV	COSMIC cancer mutations	central_nervous_system-cerebrum-glioma-astrocytoma_Grade_IV	61	3	16828	48	CNTN1,SYNE1,LRP1B
6.998e-04	-7.26	YWHAB (tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein beta)	protein interactions	7529	965	9	19454	50	PARD3,SORBS1,NHSL1,CAMK2G,NAV2,ABLIM1,MACF1,DCLK2,PITPNC1
7.064e-04	-7.26	main axon	cellular component	GO:0044304	68	3	19108	49	SLC1A2,NRCAM,PARD3
7.385e-04	-7.21	DTNBP1 (dystrobrevin binding protein 1)	protein interactions	84062	159	4	19454	50	DTNA,SYNE1,MACF1,KALRN
7.470e-04	-7.20	skin-subungual-malignant_melanoma-acral_lentiginous	COSMIC cancer mutations	skin-subungual-malignant_melanoma-acral_lentiginous	144	4	16828	48	NAV3,SYNE1,LRP1B,MACF1
7.565e-04	-7.19	ovary-carcinoma-serous_carcinoma	COSMIC cancer mutations	ovary-carcinoma-serous_carcinoma	10710	41	16828	48	TNIK,CNTN1,DPP6,LRP1B,HPSE2,SOX5,NRXN1,CAMK2G,DCLK2,DGKG,KALRN,SYNE1,DTNA,FMN2,MSI2,NTM,FAT3,NRG3,PLCB1,RYR3,TNC,ADCY2,GPC5,MACF1,NAV3,NHSL1,SFXN5,CTNND2,SLC1A2,SLC4A4,SORBS1,TRPM3,ATP1A2,MGAT4C,NTRK2,PARD3,NAV2,NEBL,LSAMP,RORA,NRCAM
7.764e-04	-7.16	localization	biological process	GO:0051179	4474	23	18204	50	RYR3,PARD3,SFXN5,SLC1A2,PITPNC1,PLCB1,SYNE1,FMN2,ATP1A2,TRPM3,NTRK2,DCLK2,KALRN,NRCAM,SLC14A1,GPM6A,CAMK2G,DPP6,TNIK,LRP1B,NRXN1,SLC4A4,MACF1
7.948e-04	-7.14	EGF	pfam domains	PF00008	66	3	17795	49	NRXN1,LRP1B,FAT3
8.069e-04	-7.12	subungual	COSMIC cancer mutations	subungual	147	4	16828	48	MACF1,SYNE1,LRP1B,NAV3
8.074e-04	-7.12	ANK2 (ankyrin 2)	protein interactions	287	71	3	19454	50	NRCAM,TNIK,GPM6A
8.076e-04	-7.12	lamin binding	molecular function	GO:0005521	16	2	18094	48	SYNE1,PLCB1
8.309e-04	-7.09	PARD3 (par-3 family cell polarity regulator)	protein interactions	56288	287	5	19454	50	PARD3,SORBS1,PLCB1,NTRK2,DTNA
8.382e-04	-7.08	learning	biological process	GO:0007612	154	4	18204	50	PLCB1,NTRK2,NRXN1,ATP1A2
8.440e-04	-7.08	VASP (vasodilator stimulated phosphoprotein)	protein interactions	7408	288	5	19454	50	NHSL1,PARD3,NEBL,FMN2,SORBS1
8.590e-04	-7.06	CNTN2 (contactin 2)	protein interactions	6900	17	2	19454	50	NRCAM,CNTN1
8.657e-04	-7.05	asymmetric cell division	biological process	GO:0008356	16	2	18204	50	SOX5,PARD3
8.793e-04	-7.04	YWHAG (tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein gamma)	protein interactions	7532	1211	10	19454	50	PARD3,SORBS1,NAV2,CAMK2G,NHSL1,ABLIM1,FMN2,PITPNC1,MACF1,DCLK2
8.975e-04	-7.02	presynaptic membrane	cellular component	GO:0042734	168	4	19108	49	NRXN1,SLC1A2,GPM6A,CNTN1
9.082e-04	-7.00	basal_(triple-negative)_carcinoma	COSMIC cancer mutations	basal_(triple-negative)_carcinoma	2981	18	16828	48	LRP1B,CNTN1,SLC4A4,SYNE1,KALRN,PARD3,NTM,NAV2,MSI2,FMN2,TRPM3,NTRK2,ATP1A2,MACF1,ADCY2,NRCAM,NEBL,NRG3
9.082e-04	-7.00	breast-carcinoma-basal_(triple-negative)_carcinoma	COSMIC cancer mutations	breast-carcinoma-basal_(triple-negative)_carcinoma	2981	18	16828	48	SLC4A4,LRP1B,CNTN1,NRCAM,ADCY2,MACF1,NRG3,NEBL,FMN2,MSI2,NTM,NAV2,SYNE1,PARD3,KALRN,ATP1A2,NTRK2,TRPM3
9.179e-04	-6.99	cerebrum	COSMIC cancer mutations	cerebrum	67	3	16828	48	SYNE1,LRP1B,CNTN1
9.621e-04	-6.95	dendrite	cellular component	GO:0030425	620	7	19108	49	FAT3,ADCY2,NTRK2,ATP1A2,CTNND2,GPM6A,SYNE1
9.796e-04	-6.93	dendritic spine	cellular component	GO:0043197	172	4	19108	49	NTRK2,GPM6A,SYNE1,ATP1A2
9.803e-04	-6.93	dendritic tree	cellular component	GO:0097447	622	7	19108	49	ATP1A2,NTRK2,ADCY2,FAT3,SYNE1,GPM6A,CTNND2
9.906e-04	-6.92	salivary_gland-parotid-carcinoma-adenoid_cystic_carcinoma	COSMIC cancer mutations	salivary_gland-parotid-carcinoma-adenoid_cystic_carcinoma	561	7	16828	48	NRCAM,CAMK2G,RYR3,SYNE1,LRP1B,NTRK2,TNIK
1.016e-03	-6.89	spleen	COSMIC cancer mutations	spleen	408	6	16828	48	TNIK,LRP1B,SYNE1,NTM,ADCY2,SORBS1
1.022e-03	-6.89	neuron spine	cellular component	GO:0044309	174	4	19108	49	GPM6A,ATP1A2,SYNE1,NTRK2
1.037e-03	-6.87	Ig-like_dom	interpro domains	IPR007110	432	6	18521	50	NTRK2,NRCAM,CNTN1,KALRN,LSAMP,NTM
1.057e-03	-6.85	metal ion transmembrane transporter activity	molecular function	GO:0046873	442	6	18094	48	ATP1A2,SLC1A2,SLC4A4,TRPM3,RYR3,GPM6A
1.155e-03	-6.76	AFDN (afadin, adherens junction formation factor)	protein interactions	4301	309	5	19454	50	PARD3,SORBS1,NRXN1,MACF1,DTNA
1.165e-03	-6.76	bone-femur-chondrosarcoma	COSMIC cancer mutations	bone-femur-chondrosarcoma	419	6	16828	48	LRP1B,ADCY2,DPP6,NAV2,SLC4A4,HPSE2
1.178e-03	-6.74	central_nervous_system-brain-glioma-oligodendroglioma_Grade_II	COSMIC cancer mutations	central_nervous_system-brain-glioma-oligodendroglioma_Grade_II	73	3	16828	48	MACF1,SYNE1,NAV2
1.178e-03	-6.74	parotid	COSMIC cancer mutations	parotid	578	7	16828	48	LRP1B,SYNE1,NTRK2,TNIK,NRCAM,CAMK2G,RYR3
1.186e-03	-6.74	bone-Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour	COSMIC cancer mutations	bone-Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour	6023	28	16828	48	NAV2,PARD3,NTRK2,ATP1A2,TRPM3,NRCAM,RORA,NEBL,CTNND2,SLC4A4,ABLIM1,DTNA,KALRN,SYNE1,DGKG,NKAIN3,NAV3,MACF1,ADCY2,TNC,RYR3,NRG3,FAT3,LRP1B,CNTN1,DCLK2,CAMK2G,SOX5
1.194e-03	-6.73	PDZD2 (PDZ domain containing 2)	protein interactions	23037	20	2	19454	50	CTNND2,NRXN1
1.218e-03	-6.71	Adrenergic signaling in cardiomyocytes	KEGG pathways	hsa04261	144	4	7161	24	PLCB1,CAMK2G,ATP1A2,ADCY2
1.218e-03	-6.71	Adrenergic signaling in cardiomyocytes	KEGG pathways	ko04261	144	4	7161	24	PLCB1,CAMK2G,ADCY2,ATP1A2
1.222e-03	-6.71	KIF20A (kinesin family member 20A)	protein interactions	10112	1044	9	19454	50	NAV3,MACF1,PARD3,NEBL,MSI2,NAV2,SYNE1,RORA,ABLIM1
1.224e-03	-6.71	cervix-carcinoma-squamous_cell_carcinoma	COSMIC cancer mutations	cervix-carcinoma-squamous_cell_carcinoma	11789	43	16828	48	NEBL,NRCAM,RORA,LSAMP,ATP1A2,NTRK2,MGAT4C,TRPM3,NAV2,PARD3,GPM6A,SLC1A2,ABLIM1,SLC4A4,SORBS1,NHSL1,PITPNC1,SFXN5,CTNND2,PLCB1,RYR3,TNC,FAT3,NRG3,NAV3,ADCY2,GPC5,MACF1,DGKG,DTNA,FMN2,NTM,RFX4,KALRN,SYNE1,HPSE2,NRXN1,DCLK2,SOX5,CNTN1,TNIK,DPP6,LRP1B
1.225e-03	-6.70	oligodendroglioma_Grade_II	COSMIC cancer mutations	oligodendroglioma_Grade_II	74	3	16828	48	SYNE1,MACF1,NAV2
1.236e-03	-6.70	neural retina development	biological process	GO:0003407	77	3	18204	50	NTRK2,GPM6A,FAT3
1.238e-03	-6.69	cervix	COSMIC cancer mutations	cervix	11793	43	16828	48	PARD3,GPM6A,NAV2,TRPM3,MGAT4C,NTRK2,ATP1A2,RORA,LSAMP,NRCAM,NEBL,CTNND2,SFXN5,PITPNC1,NHSL1,SORBS1,SLC4A4,SLC1A2,ABLIM1,KALRN,SYNE1,RFX4,NTM,FMN2,DTNA,DGKG,GPC5,MACF1,ADCY2,NAV3,FAT3,NRG3,TNC,RYR3,PLCB1,LRP1B,DPP6,TNIK,CNTN1,SOX5,DCLK2,NRXN1,HPSE2
1.239e-03	-6.69	functioning	COSMIC cancer mutations	functioning	1803	13	16828	48	NHSL1,CNTN1,SLC1A2,HPSE2,SOX5,NTRK2,DGKG,TRPM3,FMN2,SYNE1,RFX4,NRG3,NRCAM
1.239e-03	-6.69	adrenal_gland-adrenal_gland-adrenal_cortical_carcinoma-functioning	COSMIC cancer mutations	adrenal_gland-adrenal_gland-adrenal_cortical_carcinoma-functioning	1803	13	16828	48	SLC1A2,HPSE2,SOX5,NHSL1,CNTN1,NRG3,NRCAM,DGKG,NTRK2,TRPM3,FMN2,SYNE1,RFX4
1.246e-03	-6.69	somatodendritic compartment	cellular component	GO:0036477	842	8	19108	49	FAT3,ADCY2,NTRK2,ATP1A2,NRXN1,CTNND2,GPM6A,SYNE1
1.277e-03	-6.66	postsynaptic density	cellular component	GO:0014069	317	5	19108	49	TNIK,NRCAM,CTNND2,KALRN,NTRK2
1.313e-03	-6.64	ATP binding	molecular function	GO:0005524	1467	11	18094	48	NAV2,ADCY2,DGKG,NAV3,NTRK2,TNIK,CAMK2G,MAPK10,DCLK2,ATP1A2,KALRN
1.318e-03	-6.63	TENM1 (teneurin transmembrane protein 1)	protein interactions	10178	21	2	19454	50	SORBS1,MACF1
1.349e-03	-6.61	EF-hand	gene3d domains	1.10.238.10	272	5	14470	44	RYR3,DGKG,MACF1,PLCB1,DTNA
1.361e-03	-6.60	adherens junction	cellular component	GO:0005912	188	4	19108	49	CTNNA2,PARD3,CTNND2,SORBS1
1.380e-03	-6.59	Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour	COSMIC cancer mutations	Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour	7434	32	16828	48	TNC,RYR3,NRG3,FAT3,NKAIN3,NAV3,MACF1,ADCY2,DGKG,FMN2,DTNA,KALRN,SYNE1,DCLK2,NRXN1,CAMK2G,SOX5,TNIK,CNTN1,LRP1B,NEBL,NRCAM,RORA,NTRK2,ATP1A2,TRPM3,NAV2,PARD3,SLC4A4,ABLIM1,SORBS1,CTNND2
1.397e-03	-6.57	stress fiber	cellular component	GO:0001725	86	3	19108	49	SORBS1,NEBL,ABLIM1
1.397e-03	-6.57	contractile actin filament bundle	cellular component	GO:0097517	86	3	19108	49	ABLIM1,NEBL,SORBS1
1.405e-03	-6.57	signaling	biological process	GO:0023052	4968	24	18204	50	SLC1A2,ADCY2,MAPK10,CNTN1,RYR3,PLCB1,FMN2,DTNA,NRXN1,PITPNC1,PARD3,ATP1A2,DCLK2,CTNND2,NTRK2,SORBS1,CAMK2G,DGKG,NRG3,KALRN,TNIK,MACF1,RORA,TNC
1.414e-03	-6.56	Ser/Thr_kinase_AS	interpro domains	IPR008271	308	5	18521	50	TNIK,DCLK2,KALRN,MAPK10,CAMK2G
1.425e-03	-6.55	behavior	biological process	GO:0007610	619	7	18204	50	PLCB1,NTRK2,ATP1A2,NRXN1,NAV2,CNTN1,SLC1A2
1.446e-03	-6.54	monoatomic ion transmembrane transport	biological process	GO:0034220	804	8	18204	50	SLC4A4,ATP1A2,TRPM3,PLCB1,GPM6A,SFXN5,SLC1A2,RYR3
1.473e-03	-6.52	leg	COSMIC cancer mutations	leg	969	9	16828	48	NEBL,SLC4A4,NRG3,PLCB1,CNTN1,SYNE1,LRP1B,NTM,FMN2
1.484e-03	-6.51	APC (APC regulator of WNT signaling pathway)	protein interactions	324	327	5	19454	50	SYNE1,NAV2,MACF1,NAV3,PARD3
1.489e-03	-6.51	Oxytocin signaling pathway	KEGG pathways	ko04921	152	4	7161	24	PLCB1,ADCY2,RYR3,CAMK2G
1.489e-03	-6.51	Oxytocin signaling pathway	KEGG pathways	hsa04921	152	4	7161	24	PLCB1,ADCY2,CAMK2G,RYR3
1.537e-03	-6.48	cellular component organization	biological process	GO:0016043	5636	26	18204	50	ABLIM1,NRCAM,GPM6A,NRG3,KALRN,NRXN1,NAV2,TNIK,MACF1,TNC,SLC1A2,HPSE2,NEBL,CNTN1,PITPNC1,FAT3,CTNNA2,RYR3,PARD3,TRPM3,CTNND2,DCLK2,FMN2,SORBS1,RFX4,SYNE1
1.546e-03	-6.47	adrenal_gland-adrenal_gland-adrenal_cortical_carcinoma-virilizing_syndrome_producing	COSMIC cancer mutations	adrenal_gland-adrenal_gland-adrenal_cortical_carcinoma-virilizing_syndrome_producing	298	5	16828	48	TNC,ATP1A2,LRP1B,CTNND2,FMN2
1.548e-03	-6.47	SFN (stratifin)	protein interactions	2810	671	7	19454	50	TNIK,ABLIM1,MACF1,NAV2,FMN2,SORBS1,PARD3
1.567e-03	-6.46	chondrosarcoma	COSMIC cancer mutations	chondrosarcoma	1181	10	16828	48	DPP6,LRP1B,KALRN,NAV2,CNTN1,ADCY2,LSAMP,NAV3,HPSE2,SLC4A4
1.582e-03	-6.45	TIMM10B (translocase of inner mitochondrial membrane 10B)	protein interactions	26515	23	2	19454	50	HPSE2,MSI2
1.587e-03	-6.45	asymmetric synapse	cellular component	GO:0032279	333	5	19108	49	NRCAM,NTRK2,CTNND2,KALRN,TNIK
1.589e-03	-6.44	regulation of sodium ion transport	biological process	GO:0002028	84	3	18204	50	CNTN1,NKAIN3,ATP1A2
1.603e-03	-6.44	serous_carcinoma	COSMIC cancer mutations	serous_carcinoma	10987	41	16828	48	TNIK,CNTN1,DPP6,LRP1B,HPSE2,CAMK2G,NRXN1,DCLK2,SOX5,DGKG,MSI2,DTNA,FMN2,NTM,SYNE1,KALRN,RYR3,PLCB1,TNC,FAT3,NRG3,NAV3,ADCY2,MACF1,GPC5,NHSL1,SFXN5,CTNND2,SLC1A2,SLC4A4,SORBS1,ATP1A2,MGAT4C,NTRK2,TRPM3,NAV2,PARD3,NEBL,NRCAM,LSAMP,RORA
1.614e-03	-6.43	regulation of membrane potential	biological process	GO:0042391	463	6	18204	50	NRCAM,SYNE1,SLC4A4,NTRK2,ATP1A2,NRXN1
1.628e-03	-6.42	Bile secretion	KEGG pathways	hsa04976	71	3	7161	24	SLC4A4,ATP1A2,ADCY2
1.628e-03	-6.42	Bile secretion	KEGG pathways	ko04976	71	3	7161	24	SLC4A4,ATP1A2,ADCY2
1.655e-03	-6.40	DGUOK (deoxyguanosine kinase)	protein interactions	1716	91	3	19454	50	GPM6A,NTM,CNTN1
1.655e-03	-6.40	TRIO (trio Rho guanine nucleotide exchange factor)	protein interactions	7204	91	3	19454	50	NAV3,PARD3,NAV2
1.695e-03	-6.38	Adherens junction	KEGG pathways	ko04520	72	3	7161	24	CTNNA2,PARD3,SORBS1
1.695e-03	-6.38	Adherens junction	KEGG pathways	hsa04520	72	3	7161	24	CTNNA2,PARD3,SORBS1
1.695e-03	-6.38	actomyosin	cellular component	GO:0042641	92	3	19108	49	ABLIM1,NEBL,SORBS1
1.700e-03	-6.38	transport across blood-brain barrier	biological process	GO:0150104	86	3	18204	50	ATP1A2,SLC1A2,SLC4A4
1.700e-03	-6.38	vascular transport	biological process	GO:0010232	86	3	18204	50	ATP1A2,SLC1A2,SLC4A4
1.734e-03	-6.36	femur	COSMIC cancer mutations	femur	1197	10	16828	48	SLC4A4,NRG3,HPSE2,RYR3,GPC5,ADCY2,LRP1B,DPP6,NAV2,FMN2
1.743e-03	-6.35	Actinin_actin-bd_CS	interpro domains	IPR001589	23	2	18521	50	MACF1,SYNE1
1.776e-03	-6.33	Prot_kinase_dom	interpro domains	IPR000719	480	6	18521	50	KALRN,TNIK,DCLK2,NTRK2,CAMK2G,MAPK10
1.782e-03	-6.33	HS-GAG degradation	REACTOME pathways	R-HSA-2024096	21	2	10285	31	HPSE2,GPC5
1.813e-03	-6.31	bone-femur-other-chondroblastoma	COSMIC cancer mutations	bone-femur-other-chondroblastoma	183	4	16828	48	NRG3,RYR3,LRP1B,GPC5
1.825e-03	-6.31	adenyl ribonucleotide binding	molecular function	GO:0032559	1528	11	18094	48	KALRN,ATP1A2,DCLK2,TNIK,MAPK10,CAMK2G,ADCY2,NAV2,DGKG,NAV3,NTRK2
1.835e-03	-6.30	Thyroid hormone synthesis	KEGG pathways	ko04918	74	3	7161	24	PLCB1,ATP1A2,ADCY2
1.835e-03	-6.30	Thyroid hormone synthesis	KEGG pathways	hsa04918	74	3	7161	24	PLCB1,ADCY2,ATP1A2
1.853e-03	-6.29	postsynaptic specialization	cellular component	GO:0099572	345	5	19108	49	NRCAM,CTNND2,KALRN,NTRK2,TNIK
1.870e-03	-6.28	ADAMTS13 (ADAM metallopeptidase with thrombospondin type 1 motif 13)	protein interactions	11093	25	2	19454	50	MACF1,FAT3
1.913e-03	-6.26	human chr3q27.2-q27.3	chromosome location	human chr3q27.2-q27.3	1	1	26134	50	DGKG
1.913e-03	-6.26	human chr3q21.1-q21.2	chromosome location	human chr3q21.1-q21.2	1	1	26134	50	KALRN
1.913e-03	-6.26	human chr4q31.23-q31.3	chromosome location	human chr4q31.23-q31.3	1	1	26134	50	DCLK2
1.913e-03	-6.26	human chr10p11.22-p11.21	chromosome location	human chr10p11.22-p11.21	1	1	26134	50	PARD3
1.913e-03	-6.26	human chr9q21.12-q21.13	chromosome location	human chr9q21.12-q21.13	1	1	26134	50	TRPM3
1.913e-03	-6.26	human chr3q26.2-q26.31	chromosome location	human chr3q26.2-q26.31	1	1	26134	50	TNIK
1.913e-03	-6.26	human chr15q13.3-q14	chromosome location	human chr15q13.3-q14	1	1	26134	50	RYR3
1.913e-03	-6.26	human chr2q22.1-q22.2	chromosome location	human chr2q22.1-q22.2	1	1	26134	50	LRP1B
1.913e-03	-6.26	human chr12q21.31-q21.32	chromosome location	human chr12q21.31-q21.32	1	1	26134	50	MGAT4C
1.915e-03	-6.26	actin filament bundle	cellular component	GO:0032432	96	3	19108	49	ABLIM1,SORBS1,NEBL
1.921e-03	-6.25	FN3	smart domains	SM00060	149	4	9717	35	KALRN,TNC,NRCAM,CNTN1
1.972e-03	-6.23	cellular component assembly	biological process	GO:0022607	2472	15	18204	50	NRG3,NRCAM,ABLIM1,GPM6A,TNIK,NRXN1,RYR3,PARD3,SLC1A2,NEBL,CNTN1,RFX4,FMN2,SORBS1,TRPM3
1.987e-03	-6.22	PLCB3 (phospholipase C beta 3)	protein interactions	5331	97	3	19454	50	PARD3,PLCB1,CAMK2G
2.023e-03	-6.20	NRCAM (neuronal cell adhesion molecule)	protein interactions	4897	26	2	19454	50	MACF1,NRCAM
2.026e-03	-6.20	calcium ion binding	molecular function	GO:0005509	683	7	18094	48	FAT3,LRP1B,MACF1,NRXN1,PLCB1,DGKG,RYR3
2.035e-03	-6.20	skin-neck-malignant_melanoma	COSMIC cancer mutations	skin-neck-malignant_melanoma	1223	10	16828	48	TNC,PLCB1,GPC5,ADCY2,ATP1A2,CNTN1,TRPM3,SYNE1,LRP1B,CTNND2
2.047e-03	-6.19	FRS2 (fibroblast growth factor receptor substrate 2)	protein interactions	10818	98	3	19454	50	NTRK2,PARD3,SORBS1
2.077e-03	-6.18	phosphotransferase activity, alcohol group as acceptor	molecular function	GO:0016773	686	7	18094	48	NTRK2,DGKG,CAMK2G,MAPK10,TNIK,DCLK2,KALRN
2.084e-03	-6.17	skin-upper_back-malignant_melanoma	COSMIC cancer mutations	skin-upper_back-malignant_melanoma	319	5	16828	48	MACF1,SYNE1,KALRN,GPC5,CNTN1
2.136e-03	-6.15	neck	COSMIC cancer mutations	neck	1231	10	16828	48	ADCY2,GPC5,PLCB1,TNC,SYNE1,LRP1B,CTNND2,CNTN1,ATP1A2,TRPM3
2.141e-03	-6.15	virilizing_syndrome_producing	COSMIC cancer mutations	virilizing_syndrome_producing	321	5	16828	48	ATP1A2,TNC,FMN2,CTNND2,LRP1B
2.152e-03	-6.14	EGF-type_Asp/Asn_hydroxyl_site	interpro domains	IPR000152	95	3	18521	50	FAT3,NRXN1,LRP1B
2.176e-03	-6.13	FN3_dom	interpro domains	IPR003961	203	4	18521	50	KALRN,CNTN1,TNC,NRCAM
2.176e-03	-6.13	FN3_sf	interpro domains	IPR036116	203	4	18521	50	NRCAM,TNC,CNTN1,KALRN
2.178e-03	-6.13	CXADR (CXADR Ig-like cell adhesion molecule)	protein interactions	1525	357	5	19454	50	NEBL,PARD3,SORBS1,MACF1,TNIK
2.181e-03	-6.13	SH3BP5 (SH3 domain binding protein 5)	protein interactions	9467	27	2	19454	50	SYNE1,MAPK10
2.181e-03	-6.13	KCNJ12 (potassium inwardly rectifying channel subfamily J member 12)	protein interactions	3768	27	2	19454	50	ABLIM1,DTNA
2.183e-03	-6.13	intracellular signal transduction	biological process	GO:0035556	1505	11	18204	50	TNIK,DGKG,NRG3,KALRN,ATP1A2,DCLK2,PLCB1,FMN2,MAPK10,ADCY2,RYR3
2.200e-03	-6.12	haematopoietic_and_lymphoid_tissue-spleen-lymphoid_neoplasm-marginal_zone_lymphoma	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue-spleen-lymphoid_neoplasm-marginal_zone_lymphoma	323	5	16828	48	ADCY2,LRP1B,SORBS1,SYNE1,NTM
2.238e-03	-6.10	modulation of chemical synaptic transmission	biological process	GO:0050804	494	6	18204	50	NRXN1,ATP1A2,NTRK2,PLCB1,NRG3,SYNE1
2.261e-03	-6.09	regulation of trans-synaptic signaling	biological process	GO:0099177	495	6	18204	50	ATP1A2,NRXN1,NTRK2,NRG3,PLCB1,SYNE1
2.319e-03	-6.07	poly(U) RNA binding	molecular function	GO:0008266	27	2	18094	48	MSI2,RBMS3
2.342e-03	-6.06	oesophagus-lower_third-carcinoma-squamous_cell_carcinoma	COSMIC cancer mutations	oesophagus-lower_third-carcinoma-squamous_cell_carcinoma	3507	19	16828	48	PLCB1,RYR3,MACF1,GPC5,ADCY2,NAV3,TRPM3,DGKG,ATP1A2,PARD3,SYNE1,NAV2,FMN2,SLC4A4,HPSE2,DCLK2,CNTN1,CTNND2,LRP1B
2.345e-03	-6.06	LRRC7 (leucine rich repeat containing 7)	protein interactions	57554	28	2	19454	50	CAMK2G,CTNND2
2.351e-03	-6.05	upper_back	COSMIC cancer mutations	upper_back	328	5	16828	48	MACF1,KALRN,GPC5,SYNE1,CNTN1
2.368e-03	-6.05	neuron to neuron synapse	cellular component	GO:0098984	365	5	19108	49	TNIK,NTRK2,CTNND2,KALRN,NRCAM
2.399e-03	-6.03	calcium ion transmembrane transport	biological process	GO:0070588	205	4	18204	50	PLCB1,RYR3,GPM6A,TRPM3
2.446e-03	-6.01	marginal_zone_lymphoma	COSMIC cancer mutations	marginal_zone_lymphoma	331	5	16828	48	LRP1B,SORBS1,SYNE1,ADCY2,NTM
2.458e-03	-6.01	EGF_1	prosite domains	PS00022	174	4	12186	40	LRP1B,NRG3,TNC,FAT3
2.463e-03	-6.01	Aldosterone synthesis and secretion	KEGG pathways	hsa04925	82	3	7161	24	CAMK2G,ADCY2,PLCB1
2.463e-03	-6.01	Aldosterone synthesis and secretion	KEGG pathways	ko04925	82	3	7161	24	ADCY2,CAMK2G,PLCB1
2.484e-03	-6.00	protein kinase C-activating G protein-coupled receptor signaling pathway	biological process	GO:0007205	27	2	18204	50	DGKG,PARD3
2.545e-03	-5.97	ACTININ_1	prosite domains	PS00019	23	2	12186	40	SYNE1,MACF1
2.545e-03	-5.97	ACTININ_2	prosite domains	PS00020	23	2	12186	40	SYNE1,MACF1
2.557e-03	-5.97	IG	smart domains	SM00409	394	6	9717	35	KALRN,LSAMP,NTRK2,NTM,NRCAM,CNTN1
2.570e-03	-5.96	Itga7 (integrin subunit alpha 7)	protein interactions	81008	1	1	19454	50	TNC
2.570e-03	-5.96	Cntnap2 (contactin associated protein-like 2)	protein interactions	66797	1	1	19454	50	CNTN1
2.570e-03	-5.96	Sytl1 (synaptotagmin-like 1)	protein interactions	269589	1	1	19454	50	NRXN1
2.570e-03	-5.96	Bdnf (brain derived neurotrophic factor)	protein interactions	12064	1	1	19454	50	NTRK2
2.570e-03	-5.96	App (amyloid beta precursor protein)	protein interactions	100689222	1	1	19454	50	LRP1B
2.570e-03	-5.96	Dynlt1 (dynein light chain Tctex-type 1)	protein interactions	83462	1	1	19454	50	NTRK2
2.570e-03	-5.96	Agtrap (angiotensin II, type I receptor-associated protein)	protein interactions	11610	1	1	19454	50	PITPNC1
2.585e-03	-5.96	IG_LIKE	prosite domains	PS50835	430	6	12186	40	CNTN1,KALRN,NTRK2,NTM,NRCAM,LSAMP
2.585e-03	-5.96	Pkinase	pfam domains	PF00069	347	5	17795	49	MAPK10,CAMK2G,TNIK,DCLK2,KALRN
2.602e-03	-5.95	inorganic molecular entity transmembrane transporter activity	molecular function	GO:0015318	714	7	18094	48	SLC1A2,ATP1A2,SLC14A1,TRPM3,RYR3,GPM6A,SLC4A4
2.603e-03	-5.95	MAPRE3 (microtubule associated protein RP/EB family member 3)	protein interactions	22924	224	4	19454	50	GPM6A,ABLIM1,NAV2,MACF1
2.609e-03	-5.95	Proximal tubule bicarbonate reclamation	KEGG pathways	hsa04964	23	2	7161	24	ATP1A2,SLC4A4
2.609e-03	-5.95	Proximal tubule bicarbonate reclamation	KEGG pathways	ko04964	23	2	7161	24	ATP1A2,SLC4A4
2.636e-03	-5.94	protein serine kinase activity	molecular function	GO:0106310	362	5	18094	48	DCLK2,KALRN,CAMK2G,MAPK10,TNIK
2.653e-03	-5.93	brain-derived neurotrophic factor receptor activity	molecular function	GO:0060175	1	1	18094	48	NTRK2
2.700e-03	-5.91	SORBS1_SH3_2	interpro domains	IPR035611	1	1	18521	50	SORBS1
2.700e-03	-5.91	Contactin-1_Ig1	interpro domains	IPR036992	1	1	18521	50	CNTN1
2.700e-03	-5.91	C1_DGKgamma_rpt2	interpro domains	IPR047475	1	1	18521	50	DGKG
2.700e-03	-5.91	CH_SYNE1_rpt1	interpro domains	IPR047290	1	1	18521	50	SYNE1
2.700e-03	-5.91	Contactin-1_Ig6	interpro domains	IPR047101	1	1	18521	50	CNTN1
2.700e-03	-5.91	SORBS1_SH3_1	interpro domains	IPR035610	1	1	18521	50	SORBS1
2.700e-03	-5.91	Nebulette_SH3	interpro domains	IPR035631	1	1	18521	50	NEBL
2.700e-03	-5.91	SORBS1_SH3	interpro domains	IPR035606	1	1	18521	50	SORBS1
2.700e-03	-5.91	CH_SYNE1_rpt2	interpro domains	IPR047291	1	1	18521	50	SYNE1
2.700e-03	-5.91	NTRK2	interpro domains	IPR020455	1	1	18521	50	NTRK2
2.700e-03	-5.91	PLC-beta1_EF	interpro domains	IPR028400	1	1	18521	50	PLCB1
2.700e-03	-5.91	RBMS3_RRM2	interpro domains	IPR034406	1	1	18521	50	RBMS3
2.700e-03	-5.91	Contactin-1_Ig3	interpro domains	IPR047100	1	1	18521	50	CNTN1
2.729e-03	-5.90	ErbB signaling pathway	KEGG pathways	ko04012	85	3	7161	24	CAMK2G,NRG3,MAPK10
2.729e-03	-5.90	ErbB signaling pathway	KEGG pathways	hsa04012	85	3	7161	24	CAMK2G,MAPK10,NRG3
2.730e-03	-5.90	Kinase-like_dom_sf	interpro domains	IPR011009	523	6	18521	50	NTRK2,TNIK,DCLK2,KALRN,MAPK10,CAMK2G
2.747e-03	-5.90	regulation of nucleus organization	biological process	GO:1903353	1	1	18204	50	SYNE1
2.747e-03	-5.90	trans-synaptic signaling by neuropeptide, modulating synaptic transmission	biological process	GO:0099551	1	1	18204	50	NTRK2
2.747e-03	-5.90	trans-synaptic signaling by neuropeptide	biological process	GO:0099540	1	1	18204	50	NTRK2
2.747e-03	-5.90	chemorepulsion involved in interneuron migration from the subpallium to the cortex	biological process	GO:0021842	1	1	18204	50	NRG3
2.747e-03	-5.90	regulation of CD24 production	biological process	GO:2000559	1	1	18204	50	PLCB1
2.747e-03	-5.90	response to glyceraldehyde	biological process	GO:1905630	1	1	18204	50	PLCB1
2.747e-03	-5.90	homologous chromosome movement towards spindle pole in meiosis I anaphase	biological process	GO:0051758	1	1	18204	50	FMN2
2.747e-03	-5.90	olfactory cortex development	biological process	GO:0021989	1	1	18204	50	ATP1A2
2.747e-03	-5.90	negative regulation of calcium:sodium antiporter activity	biological process	GO:1903280	1	1	18204	50	ATP1A2
2.747e-03	-5.90	cellular response to glyceraldehyde	biological process	GO:1905631	1	1	18204	50	PLCB1
2.747e-03	-5.90	directional guidance of interneurons involved in migration from the subpallium to the cortex	biological process	GO:0021840	1	1	18204	50	NRG3
2.747e-03	-5.90	positive regulation of CD24 production	biological process	GO:2000560	1	1	18204	50	PLCB1
2.777e-03	-5.89	cellular component organization or biogenesis	biological process	GO:0071840	5850	26	18204	50	DCLK2,CTNND2,TRPM3,RFX4,SYNE1,FMN2,SORBS1,FAT3,PITPNC1,CTNNA2,CNTN1,SLC1A2,HPSE2,NEBL,PARD3,RYR3,MACF1,TNIK,NRXN1,NAV2,TNC,GPM6A,NRCAM,ABLIM1,KALRN,NRG3
2.823e-03	-5.87	Calcium signaling pathway	KEGG pathways	ko04020	181	4	7161	24	PLCB1,ADCY2,CAMK2G,RYR3
2.823e-03	-5.87	Calcium signaling pathway	KEGG pathways	hsa04020	181	4	7161	24	PLCB1,ADCY2,RYR3,CAMK2G
2.857e-03	-5.86	nuclear outer membrane	cellular component	GO:0005640	31	2	19108	49	NAV3,SYNE1
2.859e-03	-5.86	poly-pyrimidine tract binding	molecular function	GO:0008187	30	2	18094	48	MSI2,RBMS3
2.862e-03	-5.86	ACTB (actin beta)	protein interactions	60	958	8	19454	50	FMN2,MACF1,SFXN5,SORBS1,NEBL,ABLIM1,DTNA,NHSL1
2.863e-03	-5.86	myelination in peripheral nervous system	biological process	GO:0022011	29	2	18204	50	PARD3,NTRK2
2.863e-03	-5.86	peripheral nervous system axon ensheathment	biological process	GO:0032292	29	2	18204	50	NTRK2,PARD3
2.863e-03	-5.86	DST (dystonin)	protein interactions	667	230	4	19454	50	TNIK,NTRK2,ATP1A2,PARD3
2.866e-03	-5.85	beta-catenin binding	molecular function	GO:0008013	107	3	18094	48	CTNND2,RORA,CTNNA2
2.899e-03	-5.84	adenyl nucleotide binding	molecular function	GO:0030554	1620	11	18094	48	MAPK10,CAMK2G,TNIK,NTRK2,DGKG,NAV3,ADCY2,NAV2,ATP1A2,KALRN,DCLK2
3.005e-03	-5.81	SH3_domain	interpro domains	IPR001452	222	4	18521	50	NEBL,KALRN,SORBS1,MACF1
3.060e-03	-5.79	Ig-like_fold	interpro domains	IPR013783	721	7	18521	50	CNTN1,NTRK2,NRCAM,LSAMP,NTM,KALRN,TNC
3.062e-03	-5.79	neurotransmitter uptake	biological process	GO:0001504	30	2	18204	50	SLC1A2,ATP1A2
3.088e-03	-5.78	anion binding	molecular function	GO:0043168	2412	14	18094	48	PARD3,MAPK10,NAV3,KALRN,DCLK2,PLCB1,CAMK2G,TNIK,NTRK2,DGKG,NAV2,ADCY2,PITPNC1,ATP1A2
3.093e-03	-5.78	MARK3 (microtubule affinity regulating kinase 3)	protein interactions	4140	235	4	19454	50	DTNA,MACF1,NTRK2,PARD3
3.108e-03	-5.77	Muscle contraction	REACTOME pathways	R-HSA-397014	204	4	10285	31	RYR3,ATP1A2,CAMK2G,SORBS1
3.152e-03	-5.76	kinase activity	molecular function	GO:0016301	739	7	18094	48	KALRN,DCLK2,TNIK,CAMK2G,MAPK10,DGKG,NTRK2
3.181e-03	-5.75	PROTEIN_KINASE_ST	prosite domains	PS00108	308	5	12186	40	CAMK2G,KALRN,TNIK,DCLK2,MAPK10
3.202e-03	-5.74	presynapse	cellular component	GO:0098793	569	6	19108	49	NTRK2,SLC1A2,NRXN1,GPM6A,TNIK,CNTN1
3.237e-03	-5.73	LCOR (ligand dependent nuclear receptor corepressor)	protein interactions	84458	238	4	19454	50	NAV3,NRCAM,MACF1,LRP1B
3.252e-03	-5.73	NTKRECEPTOR2	prints domains	PR01941	1	1	5227	17	NTRK2
3.301e-03	-5.71	axon guidance	biological process	GO:0007411	224	4	18204	50	CNTN1,NRCAM,NRXN1,KALRN
3.301e-03	-5.71	neuron projection guidance	biological process	GO:0097485	224	4	18204	50	KALRN,CNTN1,NRCAM,NRXN1
3.329e-03	-5.71	skin-arm-malignant_melanoma	COSMIC cancer mutations	skin-arm-malignant_melanoma	1308	10	16828	48	SLC4A4,SORBS1,MACF1,ATP1A2,TRPM3,NAV2,NTM,SYNE1,LRP1B,KALRN
3.375e-03	-5.69	cell migration	biological process	GO:0016477	921	8	18204	50	CTNNA2,FAT3,GPM6A,NRCAM,NRG3,NTRK2,GPC5,FMN2
3.391e-03	-5.69	Ion channel transport	REACTOME pathways	R-HSA-983712	209	4	10285	31	CAMK2G,RYR3,ATP1A2,TRPM3
3.401e-03	-5.68	Protein_kinase_ATP_BS	interpro domains	IPR017441	377	5	18521	50	NTRK2,TNIK,DCLK2,KALRN,CAMK2G
3.441e-03	-5.67	HAX1 (HCLS1 associated protein X-1)	protein interactions	10456	397	5	19454	50	DPP6,NTM,CNTN1,MAPK10,GPM6A
3.462e-03	-5.67	Transferase(Phosphotransferase) domain 1	gene3d domains	1.10.510.10	490	6	14470	44	DCLK2,KALRN,TNIK,CAMK2G,NTRK2,MAPK10
3.472e-03	-5.66	monoatomic ion transmembrane transporter activity	molecular function	GO:0015075	752	7	18094	48	TRPM3,RYR3,GPM6A,SFXN5,SLC4A4,SLC1A2,ATP1A2
3.504e-03	-5.65	FN3	prosite domains	PS50853	192	4	12186	40	TNC,NRCAM,CNTN1,KALRN
3.578e-03	-5.63	phosphorylation	biological process	GO:0016310	729	7	18204	50	KALRN,MAPK10,DGKG,CAMK2G,TNIK,NTRK2,DCLK2
3.590e-03	-5.63	Neuronal System	REACTOME pathways	R-HSA-112316	349	5	10285	31	NRXN1,ADCY2,PLCB1,CAMK2G,SLC1A2
3.602e-03	-5.63	DELLA	smart domains	SM01129	1	1	9717	35	MACF1
3.674e-03	-5.61	cell-cell adhesion	biological process	GO:0098609	546	6	18204	50	NRXN1,CTNND2,NRCAM,CTNNA2,FAT3,CNTN1
3.688e-03	-5.60	calcium channel activity	molecular function	GO:0005262	117	3	18094	48	GPM6A,TRPM3,RYR3
3.692e-03	-5.60	dendrite development	biological process	GO:0016358	113	3	18204	50	CTNNA2,FAT3,CTNND2
3.697e-03	-5.60	response to auditory stimulus	biological process	GO:0010996	33	2	18204	50	ATP1A2,NRXN1
3.775e-03	-5.58	arm	COSMIC cancer mutations	arm	1331	10	16828	48	MACF1,SORBS1,SLC4A4,KALRN,LRP1B,SYNE1,NAV2,NTM,TRPM3,ATP1A2
3.857e-03	-5.56	SLC5A5 (solute carrier family 5 member 5)	protein interactions	6528	36	2	19454	50	SFXN5,CAMK2G
3.879e-03	-5.55	Transmission across Chemical Synapses	REACTOME pathways	R-HSA-112315	217	4	10285	31	CAMK2G,SLC1A2,ADCY2,PLCB1
3.903e-03	-5.55	cAMP signaling pathway	KEGG pathways	hsa04024	198	4	7161	24	ADCY2,ATP1A2,CAMK2G,MAPK10
3.903e-03	-5.55	cAMP signaling pathway	KEGG pathways	ko04024	198	4	7161	24	MAPK10,CAMK2G,ADCY2,ATP1A2
3.969e-03	-5.53	NCK2 (NCK adaptor protein 2)	protein interactions	8440	252	4	19454	50	SORBS1,TNIK,NHSL1,NTRK2
3.976e-03	-5.53	salivary_gland-submandibular-carcinoma-adenoid_cystic_carcinoma	COSMIC cancer mutations	salivary_gland-submandibular-carcinoma-adenoid_cystic_carcinoma	33	2	16828	48	LRP1B,NAV2
4.031e-03	-5.51	protein kinase activity	molecular function	GO:0004672	577	6	18094	48	NTRK2,TNIK,CAMK2G,MAPK10,DCLK2,KALRN
4.068e-03	-5.50	large_intestine-caecum-adenoma	COSMIC cancer mutations	large_intestine-caecum-adenoma	229	4	16828	48	HPSE2,KALRN,LRP1B,CTNND2
4.094e-03	-5.50	transporter activity	molecular function	GO:0005215	1211	9	18094	48	SFXN5,ATP1A2,PITPNC1,SLC1A2,GPM6A,RYR3,TRPM3,SLC4A4,SLC14A1
4.099e-03	-5.50	proteoglycan binding	molecular function	GO:0043394	36	2	18094	48	HPSE2,TNC
4.119e-03	-5.49	EGF	smart domains	SM00181	184	4	9717	35	NRXN1,TNC,FAT3,LRP1B
4.145e-03	-5.49	cellular process	biological process	GO:0009987	14996	48	18204	50	DGKG,KALRN,MSI2,NRG3,SLC4A4,RORA,TNIK,TNC,MGAT4C,PITPNC1,LSAMP,SOX5,SORBS1,NHSL1,ABLIM1,NRCAM,GPC5,NRXN1,CNTN1,FAT3,SLC1A2,MAPK10,NTM,FMN2,NAV3,RFX4,PLCB1,GPM6A,CAMK2G,SLC14A1,MACF1,CTNNA2,SFXN5,PARD3,DCLK2,CTNND2,NTRK2,ATP1A2,DTNA,NAV2,LRP1B,DPP6,HPSE2,NEBL,ADCY2,RYR3,TRPM3,SYNE1
4.196e-03	-5.47	central_nervous_system-brainstem-glioma-oligoastrocytoma_Grade_III	COSMIC cancer mutations	central_nervous_system-brainstem-glioma-oligoastrocytoma_Grade_III	114	3	16828	48	SLC1A2,RYR3,SOX5
4.251e-03	-5.46	ASX_HYDROXYL	prosite domains	PS00010	100	3	12186	40	FAT3,NRXN1,LRP1B
4.364e-03	-5.43	regulation of metal ion transport	biological process	GO:0010959	393	5	18204	50	CAMK2G,CNTN1,NKAIN3,ATP1A2,DPP6
4.370e-03	-5.43	striated muscle contraction	biological process	GO:0006941	120	3	18204	50	RYR3,ATP1A2,DTNA
4.370e-03	-5.43	regulation of nervous system process	biological process	GO:0031644	120	3	18204	50	PARD3,SYNE1,NRXN1
4.408e-03	-5.42	Laminin_G_2	pfam domains	PF02210	36	2	17795	49	NRXN1,FAT3
4.445e-03	-5.42	Melanogenesis	KEGG pathways	ko04916	101	3	7161	24	PLCB1,CAMK2G,ADCY2
4.445e-03	-5.42	Retrograde endocannabinoid signaling	KEGG pathways	ko04723	101	3	7161	24	MAPK10,ADCY2,PLCB1
4.445e-03	-5.42	Melanogenesis	KEGG pathways	hsa04916	101	3	7161	24	PLCB1,CAMK2G,ADCY2
4.445e-03	-5.42	Retrograde endocannabinoid signaling	KEGG pathways	hsa04723	101	3	7161	24	ADCY2,MAPK10,PLCB1
4.449e-03	-5.42	PROTEIN_KINASE_DOM	prosite domains	PS50011	480	6	12186	40	CAMK2G,NTRK2,TNIK,DCLK2,KALRN,MAPK10
4.451e-03	-5.41	monoatomic ion transport	biological process	GO:0006811	964	8	18204	50	SLC4A4,TRPM3,ATP1A2,PLCB1,GPM6A,SLC1A2,SFXN5,RYR3
4.455e-03	-5.41	inorganic cation transmembrane transporter activity	molecular function	GO:0022890	589	6	18094	48	TRPM3,RYR3,GPM6A,SLC4A4,SLC1A2,ATP1A2
4.494e-03	-5.41	DIRAS3 (DIRAS family GTPase 3)	protein interactions	9077	261	4	19454	50	PARD3,FMN2,MACF1,DTNA
4.570e-03	-5.39	Glucagon signaling pathway	KEGG pathways	hsa04922	102	3	7161	24	PLCB1,CAMK2G,ADCY2
4.570e-03	-5.39	Glucagon signaling pathway	KEGG pathways	ko04922	102	3	7161	24	PLCB1,ADCY2,CAMK2G
4.601e-03	-5.38	SH3 Domains	gene3d domains	2.30.30.40	223	4	14470	44	NEBL,SORBS1,MACF1,KALRN
4.631e-03	-5.38	positive regulation of glucose import	biological process	GO:0046326	37	2	18204	50	SLC1A2,SORBS1
4.718e-03	-5.36	submandibular	COSMIC cancer mutations	submandibular	36	2	16828	48	NAV2,LRP1B
4.723e-03	-5.36	carbohydrate derivative binding	molecular function	GO:0097367	2251	13	18094	48	DCLK2,HPSE2,KALRN,NAV3,MAPK10,TNC,ATP1A2,NAV2,ADCY2,NTRK2,DGKG,TNIK,CAMK2G
4.735e-03	-5.35	large_intestine-colon-carcinoma	COSMIC cancer mutations	large_intestine-colon-carcinoma	2612	15	16828	48	SYNE1,KALRN,PARD3,NAV2,FMN2,TRPM3,MACF1,GPC5,ADCY2,RORA,NAV3,NRG3,TNC,LRP1B,NRXN1
4.788e-03	-5.34	action potential	biological process	GO:0001508	124	3	18204	50	NRCAM,ATP1A2,NTRK2
4.944e-03	-5.31	calcium ion transport	biological process	GO:0006816	251	4	18204	50	PLCB1,RYR3,GPM6A,TRPM3
4.945e-03	-5.31	NUFIP1 (nuclear FMR1 interacting protein 1)	protein interactions	26747	134	3	19454	50	NTM,CNTN1,GPM6A
4.966e-03	-5.31	cellular component biogenesis	biological process	GO:0044085	2716	15	18204	50	NEBL,SLC1A2,CNTN1,RYR3,PARD3,TRPM3,RFX4,SORBS1,FMN2,NRCAM,ABLIM1,GPM6A,NRG3,TNIK,NRXN1
5.068e-03	-5.28	EGF_2	prosite domains	PS01186	213	4	12186	40	NRG3,TNC,FAT3,LRP1B
5.127e-03	-5.27	RHOB (ras homolog family member B)	protein interactions	388	832	7	19454	50	TNIK,PLCB1,MACF1,FMN2,DTNA,ABLIM1,PARD3
5.134e-03	-5.27	EST1 (Est1p)	protein interactions	850934	2	1	19454	50	NAV2
5.134e-03	-5.27	C16orf46 (chromosome 16 open reading frame 46)	protein interactions	123775	2	1	19454	50	FAT3
5.134e-03	-5.27	cellular response to alkaloid	biological process	GO:0071312	39	2	18204	50	RYR3,SLC1A2
5.138e-03	-5.27	phosphate-containing compound metabolic process	biological process	GO:0006796	1681	11	18204	50	KALRN,DGKG,CAMK2G,ADCY2,MAPK10,PLCB1,RORA,DCLK2,NTRK2,ATP1A2,TNIK
5.198e-03	-5.26	RDX (radixin)	protein interactions	5962	272	4	19454	50	MACF1,ABLIM1,NEBL,MAPK10
5.231e-03	-5.25	glial cell development	biological process	GO:0021782	128	3	18204	50	PARD3,CNTN1,NTRK2
5.231e-03	-5.25	myelination	biological process	GO:0042552	128	3	18204	50	PARD3,NTRK2,CNTN1
5.265e-03	-5.25	FLOT2 (flotillin 2)	protein interactions	2319	273	4	19454	50	NTRK2,SLC14A1,PARD3,SOX5
5.283e-03	-5.24	Axon guidance	REACTOME pathways	R-HSA-422475	549	6	10285	31	ABLIM1,NRCAM,CNTN1,NRG3,KALRN,CAMK2G
5.299e-03	-5.24	heparanase activity	molecular function	GO:0030305	2	1	18094	48	HPSE2
5.329e-03	-5.23	TRIM67 (tripartite motif containing 67)	protein interactions	440730	4804	21	19454	50	CNTN1,NRCAM,PLCB1,MACF1,TNC,TNIK,LSAMP,ATP1A2,CAMK2G,SYNE1,DTNA,GPM6A,PITPNC1,DCLK2,KALRN,SLC4A4,MSI2,PARD3,NTM,CTNND2,CTNNA2
5.370e-03	-5.23	protein serine/threonine kinase activity	molecular function	GO:0004674	428	5	18094	48	TNIK,KALRN,CAMK2G,MAPK10,DCLK2
5.390e-03	-5.22	mast_cell_neoplasm	COSMIC cancer mutations	mast_cell_neoplasm	248	4	16828	48	HPSE2,NRG3,ADCY2,GPC5
5.390e-03	-5.22	haematopoietic_and_lymphoid_tissue-haematopoietic_neoplasm-mast_cell_neoplasm	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue-haematopoietic_neoplasm-mast_cell_neoplasm	248	4	16828	48	ADCY2,GPC5,NRG3,HPSE2
5.392e-03	-5.22	LRP1-like_beta_prop	interpro domains	IPR032485	2	1	18521	50	LRP1B
5.392e-03	-5.22	Formin_Cappuccino_subfam	interpro domains	IPR001265	2	1	18521	50	FMN2
5.392e-03	-5.22	Contactin-1_2_Ig1	interpro domains	IPR047102	2	1	18521	50	CNTN1
5.392e-03	-5.22	Kalirin_TRIO_PH_1	interpro domains	IPR047054	2	1	18521	50	KALRN
5.392e-03	-5.22	Glyco_hydro_79	interpro domains	IPR005199	2	1	18521	50	HPSE2
5.392e-03	-5.22	Kalirin_TRIO_SH3_2	interpro domains	IPR047053	2	1	18521	50	KALRN
5.392e-03	-5.22	Distrobrevin	interpro domains	IPR017432	2	1	18521	50	DTNA
5.392e-03	-5.22	MSI_RRM2	interpro domains	IPR034126	2	1	18521	50	MSI2
5.392e-03	-5.22	Par3/HAL_N	interpro domains	IPR021922	2	1	18521	50	PARD3
5.392e-03	-5.22	Anc-1/SYNE1/2-like	interpro domains	IPR039906	2	1	18521	50	SYNE1
5.392e-03	-5.22	Kalirin_TRIO_SH3_1	interpro domains	IPR028570	2	1	18521	50	KALRN
5.392e-03	-5.22	Urea_transporter	interpro domains	IPR004937	2	1	18521	50	SLC14A1
5.392e-03	-5.22	PLC-beta_CS	interpro domains	IPR009535	2	1	18521	50	PLCB1
5.395e-03	-5.22	cyclic purine nucleotide metabolic process	biological process	GO:0052652	40	2	18204	50	ADCY2,RORA
5.440e-03	-5.21	sarcoplasmic reticulum membrane	cellular component	GO:0033017	43	2	19108	49	RYR3,CAMK2G
5.461e-03	-5.21	axon ensheathment	biological process	GO:0008366	130	3	18204	50	NTRK2,CNTN1,PARD3
5.461e-03	-5.21	ensheathment of neurons	biological process	GO:0007272	130	3	18204	50	NTRK2,CNTN1,PARD3
5.467e-03	-5.21	central_nervous_system-brain-glioma-oligodendroglioma_Grade_III	COSMIC cancer mutations	central_nervous_system-brain-glioma-oligodendroglioma_Grade_III	249	4	16828	48	SYNE1,MACF1,NAV2,MGAT4C
5.476e-03	-5.21	Laminin_G	interpro domains	IPR001791	41	2	18521	50	NRXN1,FAT3
5.486e-03	-5.21	mesenchymal-epithelial cell signaling involved in prostate gland development	biological process	GO:0060739	2	1	18204	50	TNC
5.486e-03	-5.21	negative regulation of monocyte extravasation	biological process	GO:2000438	2	1	18204	50	PLCB1
5.486e-03	-5.21	phosphatidylinositol catabolic process	biological process	GO:0031161	2	1	18204	50	PLCB1
5.486e-03	-5.21	negative regulation of mini excitatory postsynaptic potential	biological process	GO:0061886	2	1	18204	50	SYNE1
5.486e-03	-5.21	activation of meiosis involved in egg activation	biological process	GO:0060466	2	1	18204	50	PLCB1
5.486e-03	-5.21	cellular response to fluoride	biological process	GO:1902618	2	1	18204	50	PLCB1
5.500e-03	-5.20	UT	pfam domains	PF03253	2	1	17795	49	SLC14A1
5.500e-03	-5.20	DUF5050	pfam domains	PF16472	2	1	17795	49	LRP1B
5.500e-03	-5.20	Par3_HAL_N_term	pfam domains	PF12053	2	1	17795	49	PARD3
5.500e-03	-5.20	SH3-RhoG_link	pfam domains	PF16609	2	1	17795	49	KALRN
5.500e-03	-5.20	Glyco_hydro_79n	pfam domains	PF03662	2	1	17795	49	HPSE2
5.500e-03	-5.20	DUF1154	pfam domains	PF06631	2	1	17795	49	PLCB1
5.612e-03	-5.18	calcium ion transmembrane transporter activity	molecular function	GO:0015085	136	3	18094	48	RYR3,GPM6A,TRPM3
5.614e-03	-5.18	soft_tissue-striated_muscle-rhabdomyosarcoma-embryonal	COSMIC cancer mutations	soft_tissue-striated_muscle-rhabdomyosarcoma-embryonal	2659	15	16828	48	SORBS1,CAMK2G,DPP6,CTNND2,LRP1B,FAT3,RYR3,TNC,ADCY2,RORA,MACF1,TRPM3,SYNE1,FMN2,NAV2
5.614e-03	-5.18	embryonal	COSMIC cancer mutations	embryonal	2659	15	16828	48	CAMK2G,SORBS1,DPP6,CTNND2,LRP1B,RYR3,TNC,FAT3,ADCY2,RORA,MACF1,TRPM3,FMN2,NAV2,SYNE1
5.662e-03	-5.17	cyclic nucleotide metabolic process	biological process	GO:0009187	41	2	18204	50	RORA,ADCY2
5.670e-03	-5.17	Immunoglobulins	gene3d domains	2.60.40.10	721	7	14470	44	LSAMP,CNTN1,NTM,TNC,NRCAM,KALRN,NTRK2
5.697e-03	-5.17	amino acid transport	biological process	GO:0006865	132	3	18204	50	NTRK2,SLC1A2,SFXN5
5.717e-03	-5.16	SH2D1A (SH2 domain containing 1A)	protein interactions	4068	44	2	19454	50	LRP1B,CAMK2G
5.766e-03	-5.16	phosphorus metabolic process	biological process	GO:0006793	1707	11	18204	50	MAPK10,ADCY2,NTRK2,DCLK2,ATP1A2,PLCB1,CAMK2G,DGKG,KALRN,RORA,TNIK
5.767e-03	-5.16	sarcolemma	cellular component	GO:0042383	142	3	19108	49	RYR3,ATP1A2,DTNA
5.817e-03	-5.15	regulation of sequestering of calcium ion	biological process	GO:0051282	133	3	18204	50	RYR3,PLCB1,ATP1A2
5.837e-03	-5.14	LAM_G_DOMAIN	prosite domains	PS50025	35	2	12186	40	NRXN1,FAT3
5.862e-03	-5.14	SH3	prosite domains	PS50002	222	4	12186	40	MACF1,NEBL,KALRN,SORBS1
5.922e-03	-5.13	SLC6A15 (solute carrier family 6 member 15)	protein interactions	55117	143	3	19454	50	SFXN5,NTRK2,PARD3
5.922e-03	-5.13	GPM6A (glycoprotein M6A)	protein interactions	2823	143	3	19454	50	DPP6,CNTN1,NTM
5.934e-03	-5.13	Cholinergic synapse	KEGG pathways	hsa04725	112	3	7161	24	PLCB1,ADCY2,CAMK2G
5.935e-03	-5.13	Schwann cell development	biological process	GO:0014044	42	2	18204	50	PARD3,NTRK2
5.939e-03	-5.13	central_nervous_system-brain-glioma-astrocytoma_Grade_III	COSMIC cancer mutations	central_nervous_system-brain-glioma-astrocytoma_Grade_III	1419	10	16828	48	GPC5,ADCY2,PLCB1,RYR3,NRG3,HPSE2,NAV2,LRP1B,PARD3,TRPM3
5.997e-03	-5.12	prostate	COSMIC cancer mutations	prostate	13883	46	16828	48	SLC1A2,SLC4A4,SORBS1,SFXN5,CTNND2,ATP1A2,NTRK2,TRPM3,PARD3,HPSE2,NRXN1,DCLK2,CNTN1,DPP6,RYR3,NRG3,NKAIN3,DTNA,FMN2,NTM,ABLIM1,NHSL1,SLC14A1,PITPNC1,NEBL,NRCAM,RORA,LSAMP,MGAT4C,NAV2,GPM6A,SOX5,TNIK,LRP1B,PLCB1,TNC,FAT3,NAV3,ADCY2,MACF1,GPC5,DGKG,MSI2,RFX4,KALRN,SYNE1
6.037e-03	-5.11	Calml3 (calmodulin-like 3)	protein interactions	70405	144	3	19454	50	CAMK2G,MACF1,ABLIM1
6.073e-03	-5.10	Vinculin, Vh2 four-helix bundle	gene3d domains	1.20.120.810	2	1	14470	44	CTNNA2
6.073e-03	-5.10	-	gene3d domains	6.20.350.10	2	1	14470	44	RYR3
6.159e-03	-5.09	monoatomic cation transmembrane transporter activity	molecular function	GO:0008324	630	6	18094	48	RYR3,TRPM3,GPM6A,SLC4A4,ATP1A2,SLC1A2
6.190e-03	-5.08	skin-leg-malignant_melanoma-nodular	COSMIC cancer mutations	skin-leg-malignant_melanoma-nodular	258	4	16828	48	CNTN1,SLC4A4,FMN2,SYNE1
6.190e-03	-5.08	lung-carcinoma-bronchioloalveolar_adenocarcinoma	COSMIC cancer mutations	lung-carcinoma-bronchioloalveolar_adenocarcinoma	778	7	16828	48	NTRK2,TNIK,CTNND2,SOX5,ADCY2,DCLK2,CAMK2G
6.190e-03	-5.08	bronchioloalveolar_adenocarcinoma	COSMIC cancer mutations	bronchioloalveolar_adenocarcinoma	778	7	16828	48	CTNND2,NTRK2,TNIK,ADCY2,SOX5,DCLK2,CAMK2G
6.233e-03	-5.08	Glutamatergic synapse	KEGG pathways	hsa04724	114	3	7161	24	ADCY2,PLCB1,SLC1A2
6.233e-03	-5.08	Glutamatergic synapse	KEGG pathways	ko04724	114	3	7161	24	ADCY2,PLCB1,SLC1A2
6.237e-03	-5.08	cell surface receptor protein tyrosine kinase signaling pathway	biological process	GO:0007169	428	5	18204	50	KALRN,SORBS1,NRG3,PLCB1,NTRK2
6.272e-03	-5.07	DSCR9 (Down syndrome critical region 9)	protein interactions	257203	146	3	19454	50	SYNE1,KALRN,MACF1
6.391e-03	-5.05	MOB4 (MOB family member 4, phocein)	protein interactions	25843	147	3	19454	50	ABLIM1,TNIK,CAMK2G
6.435e-03	-5.05	cytoskeleton organization	biological process	GO:0007010	1251	9	18204	50	NEBL,ABLIM1,CTNNA2,PARD3,TNIK,MACF1,DCLK2,SORBS1,FMN2
6.441e-03	-5.05	membrane raft	cellular component	GO:0045121	290	4	19108	49	SLC1A2,ADCY2,SORBS1,ATP1A2
6.462e-03	-5.04	cytoskeleton	cellular component	GO:0005856	2412	13	19108	49	NAV3,DGKG,SYNE1,PARD3,MACF1,TNIK,SORBS1,FMN2,DTNA,KALRN,NEBL,CTNNA2,ABLIM1
6.495e-03	-5.04	FORMIN	prints domains	PR00828	2	1	5227	17	FMN2
6.498e-03	-5.04	positive regulation of glucose transmembrane transport	biological process	GO:0010828	44	2	18204	50	SORBS1,SLC1A2
6.590e-03	-5.02	thyroid-carcinoma	COSMIC cancer mutations	thyroid-carcinoma	4126	20	16828	48	PLCB1,RYR3,FAT3,NAV3,MACF1,GPC5,ADCY2,LSAMP,DGKG,ATP1A2,TRPM3,NAV2,DTNA,SYNE1,PARD3,NRXN1,SOX5,TNIK,LRP1B,CTNND2
6.590e-03	-5.02	purine ribonucleoside triphosphate binding	molecular function	GO:0035639	1804	11	18094	48	DGKG,NTRK2,NAV2,ADCY2,CAMK2G,TNIK,ATP1A2,NAV3,MAPK10,DCLK2,KALRN
6.597e-03	-5.02	membrane microdomain	cellular component	GO:0098857	292	4	19108	49	SLC1A2,ADCY2,SORBS1,ATP1A2
6.618e-03	-5.02	oligoastrocytoma_Grade_III	COSMIC cancer mutations	oligoastrocytoma_Grade_III	263	4	16828	48	SYNE1,SOX5,SLC1A2,RYR3
6.676e-03	-5.01	inorganic cation transmembrane transport	biological process	GO:0098662	618	6	18204	50	ATP1A2,TRPM3,SLC4A4,PLCB1,GPM6A,RYR3
6.702e-03	-5.01	neurotransmitter transport	biological process	GO:0006836	140	3	18204	50	ATP1A2,SLC1A2,NRXN1
6.743e-03	-5.00	PFN1 (profilin 1)	protein interactions	5216	466	5	19454	50	FMN2,ABLIM1,NHSL1,MACF1,CAMK2G
6.757e-03	-5.00	NDEL1 (nudE neurodevelopment protein 1 like 1)	protein interactions	81565	150	3	19454	50	TNIK,SYNE1,KALRN
6.788e-03	-4.99	acidic amino acid transport	biological process	GO:0015800	45	2	18204	50	NTRK2,SLC1A2
6.853e-03	-4.98	cell-cell signaling	biological process	GO:0007267	822	7	18204	50	PLCB1,TNC,NTRK2,NRXN1,CAMK2G,DTNA,SLC1A2
6.875e-03	-4.98	transmembrane transport	biological process	GO:0055085	1264	9	18204	50	RYR3,SFXN5,SLC1A2,SLC14A1,GPM6A,PLCB1,ATP1A2,TRPM3,SLC4A4
6.881e-03	-4.98	TNIK (TRAF2 and NCK interacting kinase)	protein interactions	23043	151	3	19454	50	MACF1,SYNE1,TNIK
6.884e-03	-4.98	large_intestine-adenoma	COSMIC cancer mutations	large_intestine-adenoma	266	4	16828	48	RYR3,NAV3,SOX5,LRP1B
6.890e-03	-4.98	learning or memory	biological process	GO:0007611	276	4	18204	50	NRXN1,ATP1A2,NTRK2,PLCB1
7.021e-03	-4.96	Neurotrophin signaling pathway	KEGG pathways	ko04722	119	3	7161	24	CAMK2G,MAPK10,NTRK2
7.021e-03	-4.96	Neurotrophin signaling pathway	KEGG pathways	hsa04722	119	3	7161	24	NTRK2,MAPK10,CAMK2G
7.084e-03	-4.95	neuron recognition	biological process	GO:0008038	46	2	18204	50	NRCAM,NTM
7.213e-03	-4.93	system process	biological process	GO:0003008	2015	12	18204	50	RYR3,SLC1A2,CTNNA2,PLCB1,ATP1A2,NTRK2,ABLIM1,NRCAM,DTNA,NRXN1,NAV2,SLC4A4
7.295e-03	-4.92	haematopoietic_and_lymphoid_tissue-small_intestine-lymphoid_neoplasm-enteropathy_type_T_cell_lymphoma	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue-small_intestine-lymphoid_neoplasm-enteropathy_type_T_cell_lymphoma	45	2	16828	48	MACF1,MGAT4C
7.295e-03	-4.92	enteropathy_type_T_cell_lymphoma	COSMIC cancer mutations	enteropathy_type_T_cell_lymphoma	45	2	16828	48	MACF1,MGAT4C
7.312e-03	-4.92	metal ion transport	biological process	GO:0030001	630	6	18204	50	PLCB1,SLC4A4,TRPM3,ATP1A2,RYR3,GPM6A
7.330e-03	-4.92	MAGI3 (membrane associated guanylate kinase, WW and PDZ domain containing 3)	protein interactions	260425	50	2	19454	50	NRCAM,PARD3
7.386e-03	-4.91	regulation of neuron migration	biological process	GO:2001222	47	2	18204	50	CTNNA2,NRG3
7.386e-03	-4.91	Schwann cell differentiation	biological process	GO:0014037	47	2	18204	50	NTRK2,PARD3
7.455e-03	-4.90	PROTEIN_KINASE_ATP	prosite domains	PS00107	377	5	12186	40	DCLK2,NTRK2,TNIK,KALRN,CAMK2G
7.521e-03	-4.89	adult behavior	biological process	GO:0030534	146	3	18204	50	NRXN1,SLC1A2,ATP1A2
7.525e-03	-4.89	CEP19 (centrosomal protein 19)	protein interactions	84984	156	3	19454	50	FMN2,PARD3,ABLIM1
7.586e-03	-4.88	regulation of localization	biological process	GO:0032879	2028	12	18204	50	DPP6,GPC5,CAMK2G,PLCB1,SYNE1,SORBS1,ATP1A2,DCLK2,NKAIN3,RYR3,SLC1A2,CNTN1
7.617e-03	-4.88	FAM171B (family with sequence similarity 171 member B)	protein interactions	165215	51	2	19454	50	NTRK2,PARD3
7.617e-03	-4.88	Ndc80 (NDC80 kinetochore complex component)	protein interactions	67052	51	2	19454	50	NHSL1,MACF1
7.646e-03	-4.87	monoatomic cation transmembrane transport	biological process	GO:0098655	636	6	18204	50	SLC4A4,GPM6A,ATP1A2,TRPM3,PLCB1,RYR3
7.675e-03	-4.87	S_TKc	smart domains	SM00220	348	5	9717	35	MAPK10,CAMK2G,KALRN,DCLK2,TNIK
7.691e-03	-4.87	Itgb1 (integrin subunit beta 1)	protein interactions	24511	3	1	19454	50	TNC
7.691e-03	-4.87	Lrrc7 (leucine rich repeat containing 7)	protein interactions	117284	3	1	19454	50	CAMK2G
7.691e-03	-4.87	QRFPR (pyroglutamylated RFamide peptide receptor)	protein interactions	84109	3	1	19454	50	NTM
7.691e-03	-4.87	TULP1 (TUB like protein 1)	protein interactions	7287	3	1	19454	50	NRXN1
7.691e-03	-4.87	BCO1 (beta-carotene oxygenase 1)	protein interactions	53630	3	1	19454	50	ABLIM1
7.832e-03	-4.85	response to organic cyclic compound	biological process	GO:0014070	843	7	18204	50	RORA,ATP1A2,TNC,PLCB1,ADCY2,SLC1A2,RYR3
7.909e-03	-4.84	SH2B2 (SH2B adaptor protein 2)	protein interactions	10603	52	2	19454	50	SORBS1,NTRK2
7.938e-03	-4.84	JUN kinase activity	molecular function	GO:0004705	3	1	18094	48	MAPK10
7.938e-03	-4.84	cysteine transmembrane transporter activity	molecular function	GO:0033229	3	1	18094	48	SLC1A2
7.938e-03	-4.84	alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity	molecular function	GO:0008454	3	1	18094	48	MGAT4C
7.938e-03	-4.84	urea channel activity	molecular function	GO:0015265	3	1	18094	48	SLC14A1
8.007e-03	-4.83	modulation of excitatory postsynaptic potential	biological process	GO:0098815	49	2	18204	50	NRXN1,SYNE1
8.021e-03	-4.83	YWHAZ (tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein zeta)	protein interactions	7534	1138	8	19454	50	SORBS1,PARD3,ABLIM1,NAV2,CAMK2G,NHSL1,PITPNC1,MACF1
8.030e-03	-4.82	Non-integrin membrane-ECM interactions	REACTOME pathways	R-HSA-3000171	45	2	10285	31	NRXN1,TNC
8.078e-03	-4.82	DAG_kinase_typeI_N	interpro domains	IPR029477	3	1	18521	50	DGKG
8.078e-03	-4.82	ROR_rcpt	interpro domains	IPR003079	3	1	18521	50	RORA
8.078e-03	-4.82	SPRY2_RyR	interpro domains	IPR035764	3	1	18521	50	RYR3
8.078e-03	-4.82	Ryan_recept	interpro domains	IPR013333	3	1	18521	50	RYR3
8.078e-03	-4.82	Myelin_PLP	interpro domains	IPR001614	3	1	18521	50	GPM6A
8.078e-03	-4.82	NR_DBD_ROR	interpro domains	IPR044101	3	1	18521	50	RORA
8.078e-03	-4.82	NTRK_LRRCT	interpro domains	IPR031635	3	1	18521	50	NTRK2
8.078e-03	-4.82	RYDR_Jsol	interpro domains	IPR048581	3	1	18521	50	RYR3
8.078e-03	-4.82	SPRY3_RyR	interpro domains	IPR035762	3	1	18521	50	RYR3
8.078e-03	-4.82	Myelin_PLP_CS	interpro domains	IPR018237	3	1	18521	50	GPM6A
8.078e-03	-4.82	Vinculin_CS	interpro domains	IPR000633	3	1	18521	50	CTNNA2
8.078e-03	-4.82	SPRY1_RyR	interpro domains	IPR035761	3	1	18521	50	RYR3
8.078e-03	-4.82	Ryanrecept_TM4-6	interpro domains	IPR009460	3	1	18521	50	RYR3
8.078e-03	-4.82	SoHo_dom	interpro domains	IPR003127	3	1	18521	50	SORBS1
8.078e-03	-4.82	Ryanodine_rcpt	interpro domains	IPR003032	3	1	18521	50	RYR3
8.078e-03	-4.82	DGK_typeI_N_sf	interpro domains	IPR038199	3	1	18521	50	DGKG
8.078e-03	-4.82	PLC-beta_C	interpro domains	IPR014815	3	1	18521	50	PLCB1
8.078e-03	-4.82	NTRK	interpro domains	IPR020777	3	1	18521	50	NTRK2
8.078e-03	-4.82	Neuregulin	interpro domains	IPR040180	3	1	18521	50	NRG3
8.078e-03	-4.82	MAPK_JNK	interpro domains	IPR008351	3	1	18521	50	MAPK10
8.078e-03	-4.82	AKAP6/CEP68	interpro domains	IPR026696	3	1	18521	50	SYNE1
8.218e-03	-4.80	vagus nerve development	biological process	GO:0021564	3	1	18204	50	NAV2
8.218e-03	-4.80	meiotic chromosome movement towards spindle pole	biological process	GO:0016344	3	1	18204	50	FMN2
8.218e-03	-4.80	nuclear matrix anchoring at nuclear membrane	biological process	GO:0090292	3	1	18204	50	SYNE1
8.218e-03	-4.80	cysteine transport	biological process	GO:0042883	3	1	18204	50	SLC1A2
8.218e-03	-4.80	formin-nucleated actin cable assembly	biological process	GO:0070649	3	1	18204	50	FMN2
8.218e-03	-4.80	cysteine transmembrane transport	biological process	GO:1903712	3	1	18204	50	SLC1A2
8.218e-03	-4.80	response to ionomycin	biological process	GO:1904636	3	1	18204	50	PLCB1
8.218e-03	-4.80	formin-nucleated actin cable organization	biological process	GO:0110009	3	1	18204	50	FMN2
8.218e-03	-4.80	regulation of retrograde trans-synaptic signaling by endocanabinoid	biological process	GO:0099178	3	1	18204	50	PLCB1
8.218e-03	-4.80	regulation of calcium:sodium antiporter activity	biological process	GO:1903279	3	1	18204	50	ATP1A2
8.218e-03	-4.80	bud outgrowth involved in lung branching	biological process	GO:0060447	3	1	18204	50	TNC
8.218e-03	-4.80	cellular response to ionomycin	biological process	GO:1904637	3	1	18204	50	PLCB1
8.218e-03	-4.80	neuroligin clustering involved in postsynaptic membrane assembly	biological process	GO:0097118	3	1	18204	50	NRXN1
8.218e-03	-4.80	trans-synaptic signaling by BDNF, modulating synaptic transmission	biological process	GO:0099183	3	1	18204	50	NTRK2
8.218e-03	-4.80	cardiac muscle thin filament assembly	biological process	GO:0071691	3	1	18204	50	NEBL
8.218e-03	-4.80	radial glia guided migration of Purkinje cell	biological process	GO:0021942	3	1	18204	50	CTNNA2
8.218e-03	-4.80	mammary placode formation	biological process	GO:0060596	3	1	18204	50	NRG3
8.220e-03	-4.80	skin-back-malignant_melanoma	COSMIC cancer mutations	skin-back-malignant_melanoma	280	4	16828	48	ATP1A2,TNIK,LRP1B,SYNE1
8.238e-03	-4.80	LRRCT_2	pfam domains	PF16920	3	1	17795	49	NTRK2
8.238e-03	-4.80	RyR	pfam domains	PF02026	3	1	17795	49	RYR3
8.238e-03	-4.80	Sorb	pfam domains	PF02208	3	1	17795	49	SORBS1
8.238e-03	-4.80	RR_TM4-6	pfam domains	PF06459	3	1	17795	49	RYR3
8.238e-03	-4.80	Myelin_PLP	pfam domains	PF01275	3	1	17795	49	GPM6A
8.238e-03	-4.80	DAG_kinase_N	pfam domains	PF14513	3	1	17795	49	DGKG
8.238e-03	-4.80	PLC-beta_C	pfam domains	PF08703	3	1	17795	49	PLCB1
8.238e-03	-4.80	SR_plectin_7	pfam domains	PF21097	3	1	17795	49	MACF1
8.238e-03	-4.80	RYDR_Jsol	pfam domains	PF21119	3	1	17795	49	RYR3
8.244e-03	-4.80	transmembrane transporter activity	molecular function	GO:0022857	1110	8	18094	48	TRPM3,GPM6A,RYR3,SLC4A4,SLC14A1,SFXN5,ATP1A2,SLC1A2
8.266e-03	-4.80	central_nervous_system-temporoparietal-glioma-astrocytoma_Grade_IV	COSMIC cancer mutations	central_nervous_system-temporoparietal-glioma-astrocytoma_Grade_IV	48	2	16828	48	PARD3,RYR3
8.317e-03	-4.79	synaptic signaling	biological process	GO:0099536	459	5	18204	50	PLCB1,NRXN1,SLC1A2,NTRK2,DTNA
8.343e-03	-4.79	DSCAM (DS cell adhesion molecule)	protein interactions	1826	162	3	19454	50	SYNE1,KALRN,MACF1
8.398e-03	-4.78	cell-cell adhesion mediator activity	molecular function	GO:0098632	52	2	18094	48	CNTN1,NRCAM
8.476e-03	-4.77	sodium ion transmembrane transporter activity	molecular function	GO:0015081	158	3	18094	48	ATP1A2,SLC1A2,SLC4A4
8.480e-03	-4.77	nuclear membrane	cellular component	GO:0031965	314	4	19108	49	NRXN1,PLCB1,NAV3,SYNE1
8.541e-03	-4.76	protein localization to membrane	biological process	GO:0072657	462	5	18204	50	MACF1,TNIK,NRXN1,PARD3,DPP6
8.554e-03	-4.76	SNCA (synuclein alpha)	protein interactions	6622	696	6	19454	50	PLCB1,CAMK2G,MACF1,NTRK2,TNIK,GPM6A
8.620e-03	-4.75	purine ribonucleotide binding	molecular function	GO:0032555	1871	11	18094	48	TNIK,CAMK2G,MAPK10,NAV2,ADCY2,DGKG,NTRK2,NAV3,ATP1A2,KALRN,DCLK2
8.702e-03	-4.74	hindbrain development	biological process	GO:0030902	154	3	18204	50	CTNNA2,RORA,CNTN1
8.730e-03	-4.74	Cardiac conduction	REACTOME pathways	R-HSA-5576891	142	3	10285	31	CAMK2G,RYR3,ATP1A2
8.736e-03	-4.74	PLC beta mediated events	REACTOME pathways	R-HSA-112043	47	2	10285	31	ADCY2,PLCB1
8.748e-03	-4.74	ZYX (zyxin)	protein interactions	7791	316	4	19454	50	SORBS1,NEBL,ABLIM1,MACF1
8.814e-03	-4.73	SYN1 (synapsin I)	protein interactions	6853	55	2	19454	50	GPM6A,CAMK2G
8.814e-03	-4.73	PLCB1 (phospholipase C beta 1)	protein interactions	23236	55	2	19454	50	PARD3,PLCB1
8.846e-03	-4.73	regulation of monoatomic ion transport	biological process	GO:0043269	466	5	18204	50	DPP6,NKAIN3,CNTN1,CAMK2G,ATP1A2
8.869e-03	-4.73	mannosyl-glycoprotein N-acetylglucosaminyltransferases	BIOCYC pathways	META_PWY-7426	8	1	902	1	MGAT4C
8.917e-03	-4.72	SCLT1 (sodium channel and clathrin linker 1)	protein interactions	132320	166	3	19454	50	ATP1A2,NEBL,ABLIM1
8.954e-03	-4.72	Dopaminergic synapse	KEGG pathways	ko04728	130	3	7161	24	PLCB1,MAPK10,CAMK2G
8.954e-03	-4.72	Dopaminergic synapse	KEGG pathways	hsa04728	130	3	7161	24	MAPK10,CAMK2G,PLCB1
9.013e-03	-4.71	retina development in camera-type eye	biological process	GO:0060041	156	3	18204	50	NTRK2,GPM6A,FAT3
9.023e-03	-4.71	LamG	smart domains	SM00282	40	2	9717	35	FAT3,NRXN1
9.095e-03	-4.70	-	gene3d domains	6.10.250.2510	3	1	14470	44	CTNNA2
9.095e-03	-4.70	Diacylglycerol kinase alpha	gene3d domains	1.10.238.110	3	1	14470	44	DGKG
9.095e-03	-4.70	-	gene3d domains	1.10.490.160	3	1	14470	44	RYR3
9.098e-03	-4.70	G-protein mediated events	REACTOME pathways	R-HSA-112040	48	2	10285	31	PLCB1,ADCY2
9.125e-03	-4.70	L1CAM (L1 cell adhesion molecule)	protein interactions	3897	56	2	19454	50	GPM6A,CNTN1
9.207e-03	-4.69	ribonucleotide binding	molecular function	GO:0032553	1888	11	18094	48	DCLK2,KALRN,ATP1A2,NAV2,ADCY2,NAV3,DGKG,NTRK2,TNIK,CAMK2G,MAPK10
9.280e-03	-4.68	transferase activity, transferring phosphorus-containing groups	molecular function	GO:0016772	903	7	18094	48	MAPK10,CAMK2G,TNIK,NTRK2,DGKG,KALRN,DCLK2
9.295e-03	-4.68	MAPRE1 (microtubule associated protein RP/EB family member 1)	protein interactions	22919	504	5	19454	50	NAV3,MACF1,CAMK2G,NAV2,ABLIM1
9.417e-03	-4.67	Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell	REACTOME pathways	R-HSA-112314	146	3	10285	31	CAMK2G,PLCB1,ADCY2
9.442e-03	-4.66	NXPH3 (neurexophilin 3)	protein interactions	11248	57	2	19454	50	CTNNA2,NRXN1
9.541e-03	-4.65	Ig-like_dom_sf	interpro domains	IPR036179	483	5	18521	50	CNTN1,NTRK2,NRCAM,LSAMP,NTM
9.564e-03	-4.65	side of membrane	cellular component	GO:0098552	715	6	19108	49	LSAMP,DTNA,GPC5,NTM,CNTN1,NRCAM
9.616e-03	-4.64	Calcium Regulation in the Cardiac Cell	WikiPathways	WP536	151	3	5310	16	RYR3,ADCY2,CAMK2G
9.663e-03	-4.64	response to abiotic stimulus	biological process	GO:0009628	1100	8	18204	50	TNC,FMN2,SYNE1,NRXN1,ATP1A2,RORA,SLC1A2,MAPK10
9.686e-03	-4.64	Disopyramide Action Pathway	SMPDB pathways	SMP0000325	57	2	1369	4	PLCB1,ATP1A2
9.686e-03	-4.64	Quinidine Action Pathway	SMPDB pathways	SMP0000323	57	2	1369	4	PLCB1,ATP1A2
9.686e-03	-4.64	Timolol Action Pathway	SMPDB pathways	SMP0000659	57	2	1369	4	ATP1A2,PLCB1
9.686e-03	-4.64	Dobutamine Action Pathway	SMPDB pathways	SMP0000662	57	2	1369	4	PLCB1,ATP1A2
9.686e-03	-4.64	Mexiletine Action Pathway	SMPDB pathways	SMP0000329	57	2	1369	4	PLCB1,ATP1A2
9.686e-03	-4.64	Nimodipine Action Pathway	SMPDB pathways	SMP0000380	57	2	1369	4	ATP1A2,PLCB1
9.686e-03	-4.64	Amlodipine Action Pathway	SMPDB pathways	SMP0000376	57	2	1369	4	PLCB1,ATP1A2
9.686e-03	-4.64	Amiodarone Action Pathway	SMPDB pathways	SMP0000665	57	2	1369	4	PLCB1,ATP1A2
9.686e-03	-4.64	Isoprenaline Action Pathway	SMPDB pathways	SMP0000663	57	2	1369	4	PLCB1,ATP1A2
9.686e-03	-4.64	Betaxolol Action Pathway	SMPDB pathways	SMP0000299	57	2	1369	4	PLCB1,ATP1A2
9.686e-03	-4.64	Practolol Action Pathway	SMPDB pathways	SMP0000669	57	2	1369	4	PLCB1,ATP1A2
9.686e-03	-4.64	Nebivolol Action Pathway	SMPDB pathways	SMP0000366	57	2	1369	4	PLCB1,ATP1A2
9.686e-03	-4.64	Pindolol Action Pathway	SMPDB pathways	SMP0000306	57	2	1369	4	ATP1A2,PLCB1
9.686e-03	-4.64	Bopindolol Action Pathway	SMPDB pathways	SMP0000657	57	2	1369	4	PLCB1,ATP1A2
9.686e-03	-4.64	Epinephrine Action Pathway	SMPDB pathways	SMP0000661	57	2	1369	4	ATP1A2,PLCB1
9.686e-03	-4.64	Oxprenolol Action Pathway	SMPDB pathways	SMP0000304	57	2	1369	4	ATP1A2,PLCB1
9.686e-03	-4.64	Alprenolol Action Pathway	SMPDB pathways	SMP0000297	57	2	1369	4	PLCB1,ATP1A2
9.686e-03	-4.64	Metipranolol Action Pathway	SMPDB pathways	SMP0000667	57	2	1369	4	PLCB1,ATP1A2
9.686e-03	-4.64	Isradipine Action Pathway	SMPDB pathways	SMP0000378	57	2	1369	4	PLCB1,ATP1A2
9.686e-03	-4.64	Muscle/Heart Contraction	SMPDB pathways	SMP0000588	57	2	1369	4	PLCB1,ATP1A2
9.686e-03	-4.64	Tocainide Action Pathway	SMPDB pathways	SMP0000330	57	2	1369	4	PLCB1,ATP1A2
9.686e-03	-4.64	Bisoprolol Action Pathway	SMPDB pathways	SMP0000300	57	2	1369	4	ATP1A2,PLCB1
9.686e-03	-4.64	Ibutilide Action Pathway	SMPDB pathways	SMP0000332	57	2	1369	4	ATP1A2,PLCB1
9.686e-03	-4.64	Metoprolol Action Pathway	SMPDB pathways	SMP0000302	57	2	1369	4	ATP1A2,PLCB1
9.686e-03	-4.64	Carteolol Action Pathway	SMPDB pathways	SMP0000658	57	2	1369	4	PLCB1,ATP1A2
9.686e-03	-4.64	Felodipine Action Pathway	SMPDB pathways	SMP0000377	57	2	1369	4	ATP1A2,PLCB1
9.686e-03	-4.64	Nisoldipine Action Pathway	SMPDB pathways	SMP0000381	57	2	1369	4	PLCB1,ATP1A2
9.686e-03	-4.64	Penbutolol Action Pathway	SMPDB pathways	SMP0000305	57	2	1369	4	ATP1A2,PLCB1
9.686e-03	-4.64	Atenolol Action Pathway	SMPDB pathways	SMP0000298	57	2	1369	4	PLCB1,ATP1A2
9.686e-03	-4.64	Nadolol Action Pathway	SMPDB pathways	SMP0000303	57	2	1369	4	PLCB1,ATP1A2
9.686e-03	-4.64	Bevantolol Action Pathway	SMPDB pathways	SMP0000668	57	2	1369	4	ATP1A2,PLCB1
9.686e-03	-4.64	Bupranolol Action Pathway	SMPDB pathways	SMP0000670	57	2	1369	4	PLCB1,ATP1A2
9.686e-03	-4.64	Levobunolol Action Pathway	SMPDB pathways	SMP0000666	57	2	1369	4	ATP1A2,PLCB1
9.686e-03	-4.64	Procainamide (Antiarrhythmic) Action Pathway	SMPDB pathways	SMP0000324	57	2	1369	4	PLCB1,ATP1A2
9.686e-03	-4.64	Flecainide Action Pathway	SMPDB pathways	SMP0000331	57	2	1369	4	ATP1A2,PLCB1
9.686e-03	-4.64	Esmolol Action Pathway	SMPDB pathways	SMP0000301	57	2	1369	4	ATP1A2,PLCB1
9.686e-03	-4.64	Acebutolol Action Pathway	SMPDB pathways	SMP0000296	57	2	1369	4	ATP1A2,PLCB1
9.686e-03	-4.64	Sotalol Action Pathway	SMPDB pathways	SMP0000660	57	2	1369	4	ATP1A2,PLCB1
9.686e-03	-4.64	Nitrendipine Action Pathway	SMPDB pathways	SMP0000382	57	2	1369	4	ATP1A2,PLCB1
9.686e-03	-4.64	Verapamil Action Pathway	SMPDB pathways	SMP0000375	57	2	1369	4	PLCB1,ATP1A2
9.686e-03	-4.64	Fosphenytoin (Antiarrhythmic) Action Pathway	SMPDB pathways	SMP0000326	57	2	1369	4	ATP1A2,PLCB1
9.686e-03	-4.64	Arbutamine Action Pathway	SMPDB pathways	SMP0000664	57	2	1369	4	PLCB1,ATP1A2
9.686e-03	-4.64	Nifedipine Action Pathway	SMPDB pathways	SMP0000379	57	2	1369	4	PLCB1,ATP1A2
9.686e-03	-4.64	Propranolol Action Pathway	SMPDB pathways	SMP0000307	57	2	1369	4	PLCB1,ATP1A2
9.686e-03	-4.64	Diltiazem Action Pathway	SMPDB pathways	SMP0000359	57	2	1369	4	PLCB1,ATP1A2
9.714e-03	-4.63	cell motility	biological process	GO:0048870	1101	8	18204	50	NRG3,NRCAM,GPM6A,CTNNA2,FAT3,FMN2,GPC5,NTRK2
9.727e-03	-4.63	NTKRECEPTOR	prints domains	PR01939	3	1	5227	17	NTRK2
9.727e-03	-4.63	RYANODINER	prints domains	PR00795	3	1	5227	17	RYR3
9.727e-03	-4.63	JNKMAPKINASE	prints domains	PR01772	3	1	5227	17	MAPK10
9.727e-03	-4.63	MYELINPLP	prints domains	PR00214	3	1	5227	17	GPM6A
9.727e-03	-4.63	RORNUCRECPTR	prints domains	PR01293	3	1	5227	17	RORA
9.749e-03	-4.63	Gastrin-CREB signalling pathway via PKC and MAPK	REACTOME pathways	R-HSA-881907	443	5	10285	31	NRG3,PLCB1,DGKG,CAMK2G,KALRN
9.763e-03	-4.63	CILK1 (ciliogenesis associated kinase 1)	protein interactions	22858	58	2	19454	50	CAMK2G,MSI2
9.816e-03	-4.62	VINCULIN_1	prosite domains	PS00663	3	1	12186	40	CTNNA2
9.816e-03	-4.62	MYELIN_PLP_2	prosite domains	PS01004	3	1	12186	40	GPM6A
9.816e-03	-4.62	SOHO	prosite domains	PS50831	3	1	12186	40	SORBS1
9.816e-03	-4.62	MYELIN_PLP_1	prosite domains	PS00575	3	1	12186	40	GPM6A
9.833e-03	-4.62	ROR2 (receptor tyrosine kinase like orphan receptor 2)	protein interactions	4920	327	4	19454	50	SORBS1,PARD3,TNIK,DTNA
9.834e-03	-4.62	large_intestine-colon	COSMIC cancer mutations	large_intestine-colon	1291	9	16828	48	SYNE1,KALRN,LRP1B,DPP6,NAV2,FMN2,TNC,ADCY2,NAV3
9.871e-03	-4.62	cell-cell junction	cellular component	GO:0005911	513	5	19108	49	CTNNA2,ATP1A2,PARD3,CTNND2,SORBS1
1.002e-02	-4.60	Labetalol Action Pathway	SMPDB pathways	SMP0000368	58	2	1369	4	ATP1A2,PLCB1
1.002e-02	-4.60	Carvedilol Action Pathway	SMPDB pathways	SMP0000367	58	2	1369	4	PLCB1,ATP1A2
1.022e-02	-4.58	extrinsic component of membrane	cellular component	GO:0019898	175	3	19108	49	KALRN,DTNA,CTNNA2
1.022e-02	-4.58	tenascin complex	cellular component	GO:0090733	4	1	19108	49	TNC
1.022e-02	-4.58	internode region of axon	cellular component	GO:0033269	4	1	19108	49	PARD3
1.024e-02	-4.58	IGKV@ (immunoglobulin kappa variable cluster)	protein interactions	3519	4	1	19454	50	LRP1B
1.024e-02	-4.58	CALML4 (calmodulin like 4)	protein interactions	91860	4	1	19454	50	CAMK2G
1.024e-02	-4.58	Nme2 (NME/NM23 nucleoside diphosphate kinase 2)	protein interactions	18103	4	1	19454	50	RORA
1.024e-02	-4.58	CCDC126 (coiled-coil domain containing 126)	protein interactions	90693	4	1	19454	50	GPM6A
1.024e-02	-4.58	CLBA1 (clathrin binding box of aftiphilin containing 1)	protein interactions	122616	4	1	19454	50	FAT3
1.036e-02	-4.57	release of sequestered calcium ion into cytosol	biological process	GO:0051209	56	2	18204	50	PLCB1,RYR3
1.036e-02	-4.57	Lidocaine (Antiarrhythmic) Action Pathway	SMPDB pathways	SMP0000328	59	2	1369	4	PLCB1,ATP1A2
1.040e-02	-4.57	export from cell	biological process	GO:0140352	485	5	18204	50	CAMK2G,NTRK2,SLC4A4,NRXN1,ATP1A2
1.041e-02	-4.57	parathyroid-carcinoma	COSMIC cancer mutations	parathyroid-carcinoma	300	4	16828	48	MACF1,GPC5,SYNE1,RYR3
1.042e-02	-4.56	BTN2A1 (butyrophilin subfamily 2 member A1)	protein interactions	11120	60	2	19454	50	FMN2,PLCB1
1.050e-02	-4.56	response to light stimulus	biological process	GO:0009416	312	4	18204	50	SLC1A2,MAPK10,ATP1A2,SYNE1
1.054e-02	-4.55	Apelin signaling pathway	KEGG pathways	hsa04371	138	3	7161	24	ADCY2,RYR3,PLCB1
1.057e-02	-4.55	ryanodine-sensitive calcium-release channel activity	molecular function	GO:0005219	4	1	18094	48	RYR3
1.057e-02	-4.55	citrate transmembrane transporter activity	molecular function	GO:0015137	4	1	18094	48	SFXN5
1.057e-02	-4.55	brain-derived neurotrophic factor binding	molecular function	GO:0048403	4	1	18094	48	NTRK2
1.057e-02	-4.55	tricarboxylic acid transmembrane transporter activity	molecular function	GO:0015142	4	1	18094	48	SFXN5
1.058e-02	-4.55	astrocytoma_Grade_III	COSMIC cancer mutations	astrocytoma_Grade_III	1544	10	16828	48	ADCY2,GPC5,PLCB1,RYR3,NRG3,HPSE2,NAV2,LRP1B,PARD3,TRPM3
1.062e-02	-4.55	Endocrine and other factor-regulated calcium reabsorption	KEGG pathways	hsa04961	47	2	7161	24	PLCB1,ATP1A2
1.062e-02	-4.55	Endocrine and other factor-regulated calcium reabsorption	KEGG pathways	ko04961	47	2	7161	24	ATP1A2,PLCB1
1.072e-02	-4.54	negative regulation of sequestering of calcium ion	biological process	GO:0051283	57	2	18204	50	PLCB1,RYR3
1.072e-02	-4.54	visual behavior	biological process	GO:0007632	57	2	18204	50	ATP1A2,SLC1A2
1.076e-02	-4.53	PCN-like_spectrin-like_rpt	interpro domains	IPR049538	4	1	18521	50	MACF1
1.076e-02	-4.53	PLC-beta_PH	interpro domains	IPR037862	4	1	18521	50	PLCB1
1.076e-02	-4.53	PLC-beta_C_sf	interpro domains	IPR042531	4	1	18521	50	PLCB1
1.076e-02	-4.53	AbLIM_anchor	interpro domains	IPR032402	4	1	18521	50	ABLIM1
1.076e-02	-4.53	Nebulin_repeat	interpro domains	IPR000900	4	1	18521	50	NEBL
1.076e-02	-4.53	Neurofascin/L1/NrCAM_C	interpro domains	IPR026966	4	1	18521	50	NRCAM
1.076e-02	-4.53	NHS-like	interpro domains	IPR024845	4	1	18521	50	NHSL1
1.076e-02	-4.53	Ca/CaM-dep_prot_kinase-assoc	interpro domains	IPR013543	4	1	18521	50	CAMK2G
1.076e-02	-4.53	PLC-beta	interpro domains	IPR016280	4	1	18521	50	PLCB1
1.076e-02	-4.53	Desmoplakin_Spectrin-like	interpro domains	IPR041573	4	1	18521	50	MACF1
1.076e-02	-4.53	KASH	interpro domains	IPR012315	4	1	18521	50	SYNE1
1.076e-02	-4.53	TRPM_tetra_sf	interpro domains	IPR037162	4	1	18521	50	TRPM3
1.076e-02	-4.53	Glyco_transf_54	interpro domains	IPR006759	4	1	18521	50	MGAT4C
1.076e-02	-4.53	TRPM_tetra	interpro domains	IPR032415	4	1	18521	50	TRPM3
1.076e-02	-4.53	Alpha_catenin	interpro domains	IPR001033	4	1	18521	50	CTNNA2
1.076e-02	-4.53	Na/K-Atpase_Interacting	interpro domains	IPR008516	4	1	18521	50	NKAIN3
1.077e-02	-4.53	oligodendroglioma_Grade_III	COSMIC cancer mutations	oligodendroglioma_Grade_III	303	4	16828	48	NAV2,SYNE1,MACF1,MGAT4C
1.077e-02	-4.53	Sorb	smart domains	SM00459	3	1	9717	35	SORBS1
1.077e-02	-4.53	PLP	smart domains	SM00002	3	1	9717	35	GPM6A
1.077e-02	-4.53	ERBB4 (erb-b2 receptor tyrosine kinase 4)	protein interactions	2066	178	3	19454	50	NTRK2,KALRN,NRG3
1.077e-02	-4.53	CEP63 (centrosomal protein 63)	protein interactions	80254	178	3	19454	50	MACF1,SYNE1,TNIK
1.082e-02	-4.53	positive regulation of cellular component organization	biological process	GO:0051130	1122	8	18204	50	CNTN1,GPM6A,NRXN1,MACF1,NTRK2,PLCB1,NAV3,SYNE1
1.084e-02	-4.52	lung-carcinoma-squamous_cell_carcinoma	COSMIC cancer mutations	lung-carcinoma-squamous_cell_carcinoma	14664	47	16828	48	TRPM3,ATP1A2,NTRK2,PARD3,SLC1A2,SLC4A4,SORBS1,SFXN5,CTNND2,NRG3,RYR3,NKAIN3,DTNA,FMN2,NTM,HPSE2,NRXN1,DCLK2,CNTN1,DPP6,NEBL,LSAMP,RORA,NRCAM,MGAT4C,GPM6A,NAV2,ABLIM1,PITPNC1,NHSL1,SLC14A1,FAT3,PLCB1,TNC,ADCY2,GPC5,MACF1,NAV3,DGKG,RFX4,SYNE1,KALRN,MSI2,SOX5,CAMK2G,TNIK,LRP1B
1.085e-02	-4.52	adrenal_cortical_adenoma	COSMIC cancer mutations	adrenal_cortical_adenoma	161	3	16828	48	LRP1B,ADCY2,FMN2
1.088e-02	-4.52	Myometrial Relaxation and Contraction Pathways	WikiPathways	WP289	158	3	5310	16	CAMK2G,ADCY2,RYR3
1.094e-02	-4.52	germ_cell_tumour	COSMIC cancer mutations	germ_cell_tumour	867	7	16828	48	SYNE1,NTRK2,TNIK,CNTN1,MACF1,DCLK2,CAMK2G
1.094e-02	-4.52	positive regulation of mesenchymal stem cell differentiation	biological process	GO:2000741	4	1	18204	50	SOX5
1.094e-02	-4.52	response to fluoride	biological process	GO:1902617	4	1	18204	50	PLCB1
1.094e-02	-4.52	trans-synaptic signaling by BDNF	biological process	GO:0099191	4	1	18204	50	NTRK2
1.094e-02	-4.52	regulation of amino acid uptake involved in synaptic transmission	biological process	GO:0051941	4	1	18204	50	ATP1A2
1.094e-02	-4.52	brain-derived neurotrophic factor receptor signaling pathway	biological process	GO:0031547	4	1	18204	50	NTRK2
1.094e-02	-4.52	nuclear matrix organization	biological process	GO:0043578	4	1	18204	50	SYNE1
1.094e-02	-4.52	regulation of mini excitatory postsynaptic potential	biological process	GO:0061884	4	1	18204	50	SYNE1
1.094e-02	-4.52	response to glycoside	biological process	GO:1903416	4	1	18204	50	ATP1A2
1.094e-02	-4.52	regulation of glutamate uptake involved in transmission of nerve impulse	biological process	GO:0051946	4	1	18204	50	ATP1A2
1.094e-02	-4.52	regulation of systemic arterial blood pressure by baroreceptor feedback	biological process	GO:0003025	4	1	18204	50	NAV2
1.094e-02	-4.52	negative regulation of protein kinase C signaling	biological process	GO:0090038	4	1	18204	50	DGKG
1.097e-02	-4.51	TRPM_tetra	pfam domains	PF16519	4	1	17795	49	TRPM3
1.097e-02	-4.51	KASH	pfam domains	PF10541	4	1	17795	49	SYNE1
1.097e-02	-4.51	NKAIN	pfam domains	PF05640	4	1	17795	49	NKAIN3
1.097e-02	-4.51	Glyco_transf_54	pfam domains	PF04666	4	1	17795	49	MGAT4C
1.097e-02	-4.51	Bravo_FIGEY	pfam domains	PF13882	4	1	17795	49	NRCAM
1.097e-02	-4.51	CaMKII_AD	pfam domains	PF08332	4	1	17795	49	CAMK2G
1.097e-02	-4.51	PH_14	pfam domains	PF17787	4	1	17795	49	PLCB1
1.097e-02	-4.51	NHS	pfam domains	PF15273	4	1	17795	49	NHSL1
1.097e-02	-4.51	Nebulin	pfam domains	PF00880	4	1	17795	49	NEBL
1.097e-02	-4.51	AbLIM_anchor	pfam domains	PF16182	4	1	17795	49	ABLIM1
1.097e-02	-4.51	Spectrin_3	pfam domains	PF21019	4	1	17795	49	MACF1
1.097e-02	-4.51	Spectrin_4	pfam domains	PF21020	4	1	17795	49	MACF1
1.097e-02	-4.51	Spectrin_2	pfam domains	PF18373	4	1	17795	49	MACF1
1.103e-02	-4.51	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-peripheral_T_cell_lymphoma_unspecified	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-peripheral_T_cell_lymphoma_unspecified	162	3	16828	48	RYR3,MACF1,SYNE1
1.110e-02	-4.50	ARHGAP29 (Rho GTPase activating protein 29)	protein interactions	9411	62	2	19454	50	CAMK2G,PARD3
1.117e-02	-4.49	parathyroid	COSMIC cancer mutations	parathyroid	476	5	16828	48	RYR3,GPM6A,GPC5,SYNE1,MACF1
1.132e-02	-4.48	cognition	biological process	GO:0050890	319	4	18204	50	ATP1A2,NRXN1,NTRK2,PLCB1
1.141e-02	-4.47	Heparan sulfate/heparin (HS-GAG) metabolism	REACTOME pathways	R-HSA-1638091	54	2	10285	31	HPSE2,GPC5
1.143e-02	-4.47	human chr4q34.2	chromosome location	human chr4q34.2	6	1	26134	50	GPM6A
1.155e-02	-4.46	cellular response to endogenous stimulus	biological process	GO:0071495	1135	8	18204	50	SLC1A2,RYR3,NTRK2,SOX5,ATP1A2,SORBS1,PLCB1,TNC
1.161e-02	-4.46	Cell adhesion molecules (CAMs)	KEGG pathways	hsa04514	143	3	7161	24	CNTN1,NRCAM,NRXN1
1.161e-02	-4.46	Wnt signaling pathway	KEGG pathways	ko04310	143	3	7161	24	CAMK2G,MAPK10,PLCB1
1.161e-02	-4.46	Wnt signaling pathway	KEGG pathways	hsa04310	143	3	7161	24	CAMK2G,MAPK10,PLCB1
1.161e-02	-4.46	Cell adhesion molecules (CAMs)	KEGG pathways	ko04514	143	3	7161	24	CNTN1,NRCAM,NRXN1
1.163e-02	-4.45	back	COSMIC cancer mutations	back	310	4	16828	48	SYNE1,LRP1B,ATP1A2,TNIK
1.165e-02	-4.45	Activation of PKC Through G Protein-Coupled Receptor	SMPDB pathways	SMP0000749	4	1	1369	4	PLCB1
1.166e-02	-4.45	ion binding	molecular function	GO:0043167	6007	24	18094	48	MAPK10,PARD3,MACF1,FAT3,RYR3,DTNA,ABLIM1,DCLK2,CAMK2G,TNIK,RORA,DGKG,ATP1A2,SLC1A2,NAV3,KALRN,PLCB1,MGAT4C,NTRK2,ADCY2,NAV2,PITPNC1,NRXN1,LRP1B
1.182e-02	-4.44	export across plasma membrane	biological process	GO:0140115	60	2	18204	50	ATP1A2,SLC4A4
1.182e-02	-4.44	regulation of glucose import	biological process	GO:0046324	60	2	18204	50	SLC1A2,SORBS1
1.187e-02	-4.43	lower_third	COSMIC cancer mutations	lower_third	7961	31	16828	48	SORBS1,SLC4A4,CTNND2,RORA,NEBL,PARD3,NAV2,TRPM3,NTRK2,MGAT4C,ATP1A2,SOX5,DCLK2,NRXN1,HPSE2,LRP1B,DPP6,CNTN1,GPC5,MACF1,ADCY2,NAV3,FAT3,NRG3,TNC,PLCB1,RYR3,SYNE1,KALRN,FMN2,DGKG
1.198e-02	-4.42	peripheral_T_cell_lymphoma_unspecified	COSMIC cancer mutations	peripheral_T_cell_lymphoma_unspecified	167	3	16828	48	RYR3,MACF1,SYNE1
1.200e-02	-4.42	Neurotransmitter uptake and Metabolism In Glial Cells	REACTOME pathways	R-HSA-112313	4	1	10285	31	SLC1A2
1.200e-02	-4.42	Astrocytic Glutamate-Glutamine Uptake And Metabolism	REACTOME pathways	R-HSA-210455	4	1	10285	31	SLC1A2
1.204e-02	-4.42	central_nervous_system-brain-primitive_neuroectodermal_tumour-medulloblastoma-medullomyoblastoma	COSMIC cancer mutations	central_nervous_system-brain-primitive_neuroectodermal_tumour-medulloblastoma-medullomyoblastoma	485	5	16828	48	LSAMP,LRP1B,CNTN1,RYR3,SLC4A4
1.204e-02	-4.42	medullomyoblastoma	COSMIC cancer mutations	medullomyoblastoma	485	5	16828	48	CNTN1,RYR3,SLC4A4,LSAMP,LRP1B
1.205e-02	-4.42	primitive_neuroectodermal_tumour-medulloblastoma	COSMIC cancer mutations	primitive_neuroectodermal_tumour-medulloblastoma	15350	48	16828	48	CAMK2G,RBMS3,SOX5,LRP1B,TNIK,NAV3,ADCY2,MACF1,GPC5,PLCB1,TNC,FAT3,MSI2,RFX4,KALRN,SYNE1,DGKG,ABLIM1,NHSL1,SLC14A1,PITPNC1,NRCAM,LSAMP,RORA,NEBL,NAV2,GPM6A,MGAT4C,NRXN1,DCLK2,HPSE2,DPP6,CNTN1,NKAIN3,RYR3,NRG3,DTNA,FMN2,NTM,SORBS1,SLC1A2,SLC4A4,SFXN5,CTNND2,PARD3,ATP1A2,NTRK2,TRPM3
1.205e-02	-4.42	Phospholipase D signaling pathway	KEGG pathways	hsa04072	145	3	7161	24	PLCB1,DGKG,ADCY2
1.205e-02	-4.42	Phospholipase D signaling pathway	KEGG pathways	ko04072	145	3	7161	24	ADCY2,DGKG,PLCB1
1.211e-02	-4.41	-	gene3d domains	2.30.29.240	4	1	14470	44	PLCB1
1.211e-02	-4.41	Phospholipase C beta, distal C-terminal domain	gene3d domains	1.20.1230.10	4	1	14470	44	PLCB1
1.211e-02	-4.41	TRPM, tetramerisation domain	gene3d domains	1.20.5.1010	4	1	14470	44	TRPM3
1.211e-02	-4.41	-	gene3d domains	1.20.58.1060	4	1	14470	44	MACF1
1.212e-02	-4.41	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-acute_lymphoblastic_leukaemia	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-acute_lymphoblastic_leukaemia	2081	12	16828	48	TNIK,LRP1B,SLC4A4,SOX5,CAMK2G,DCLK2,ATP1A2,NTRK2,SYNE1,KALRN,DTNA,ADCY2
1.222e-02	-4.40	purine nucleotide binding	molecular function	GO:0017076	1964	11	18094	48	KALRN,ATP1A2,DCLK2,TNIK,CAMK2G,MAPK10,NAV2,ADCY2,DGKG,NTRK2,NAV3
1.224e-02	-4.40	testis-germ_cell_tumour-non_seminoma	COSMIC cancer mutations	testis-germ_cell_tumour-non_seminoma	487	5	16828	48	MACF1,CAMK2G,DCLK2,TNIK,NTRK2
1.234e-02	-4.40	establishment of localization	biological process	GO:0051234	3887	18	18204	50	SFXN5,SLC1A2,PITPNC1,RYR3,PARD3,ATP1A2,TRPM3,NTRK2,PLCB1,FMN2,SLC14A1,CAMK2G,GPM6A,KALRN,LRP1B,NRXN1,SLC4A4,MACF1
1.234e-02	-4.39	salivary_gland-carcinoma-adenoid_cystic_carcinoma	COSMIC cancer mutations	salivary_gland-carcinoma-adenoid_cystic_carcinoma	488	5	16828	48	RYR3,MGAT4C,RORA,CTNND2,SYNE1
1.249e-02	-4.38	central nervous system neuron differentiation	biological process	GO:0021953	176	3	18204	50	RORA,DCLK2,NTRK2
1.259e-02	-4.38	primary_central_nervous_system_lymphoma	COSMIC cancer mutations	primary_central_nervous_system_lymphoma	683	6	16828	48	NRG3,MACF1,NRXN1,PARD3,SYNE1,LRP1B
1.259e-02	-4.38	haematopoietic_and_lymphoid_tissue-central_nervous_system-lymphoid_neoplasm-primary_central_nervous_system_lymphoma	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue-central_nervous_system-lymphoid_neoplasm-primary_central_nervous_system_lymphoma	683	6	16828	48	MACF1,SYNE1,PARD3,LRP1B,NRXN1,NRG3
1.275e-02	-4.36	non_seminoma	COSMIC cancer mutations	non_seminoma	492	5	16828	48	MACF1,CAMK2G,DCLK2,TNIK,NTRK2
1.276e-02	-4.36	calcium- and calmodulin-dependent protein kinase complex	cellular component	GO:0005954	5	1	19108	49	CAMK2G
1.279e-02	-4.36	LINC02694 (long intergenic non-protein coding RNA 2694)	protein interactions	400359	5	1	19454	50	FAT3
1.279e-02	-4.36	RFX4 (regulatory factor X4)	protein interactions	5992	5	1	19454	50	RFX4
1.279e-02	-4.36	CAMK2N2 (calcium/calmodulin dependent protein kinase II inhibitor 2)	protein interactions	94032	5	1	19454	50	CAMK2G
1.279e-02	-4.36	SLC10A3 (solute carrier family 10 member 3)	protein interactions	8273	5	1	19454	50	SORBS1
1.279e-02	-4.36	SYT13 (synaptotagmin 13)	protein interactions	57586	5	1	19454	50	NRXN1
1.279e-02	-4.36	TMEM132E-DT (TMEM132E divergent transcript)	protein interactions	400591	5	1	19454	50	FAT3
1.279e-02	-4.36	TRPM6 (transient receptor potential cation channel subfamily M member 6)	protein interactions	140803	5	1	19454	50	TRPM3
1.287e-02	-4.35	PARD6A (par-6 family cell polarity regulator alpha)	protein interactions	50855	67	2	19454	50	PARD3,PLCB1
1.287e-02	-4.35	ARMC1 (armadillo repeat containing 1)	protein interactions	55156	67	2	19454	50	GPM6A,CNTN1
1.295e-02	-4.35	ALPHACATENIN	prints domains	PR00805	4	1	5227	17	CTNNA2
1.304e-02	-4.34	SH3_9	pfam domains	PF14604	63	2	17795	49	NEBL,SORBS1
1.307e-02	-4.34	KASH	prosite domains	PS51049	4	1	12186	40	SYNE1
1.307e-02	-4.34	NEBULIN	prosite domains	PS51216	4	1	12186	40	NEBL
1.309e-02	-4.34	Ion transport by P-type ATPases	REACTOME pathways	R-HSA-936837	58	2	10285	31	ATP1A2,CAMK2G
1.310e-02	-4.34	temporoparietal	COSMIC cancer mutations	temporoparietal	61	2	16828	48	PARD3,RYR3
1.314e-02	-4.33	inorganic ion transmembrane transport	biological process	GO:0098660	715	6	18204	50	RYR3,PLCB1,GPM6A,SLC4A4,TRPM3,ATP1A2
1.315e-02	-4.33	Signalling by NGF	REACTOME pathways	R-HSA-166520	477	5	10285	31	NTRK2,CAMK2G,KALRN,ADCY2,NRG3
1.320e-02	-4.33	high-affinity L-glutamate transmembrane transporter activity	molecular function	GO:0005314	5	1	18094	48	SLC1A2
1.320e-02	-4.33	cytoskeleton-nuclear membrane anchor activity	molecular function	GO:0140444	5	1	18094	48	SYNE1
1.320e-02	-4.33	neuroligin family protein binding	molecular function	GO:0097109	5	1	18094	48	NRXN1
1.320e-02	-4.33	glutamate:sodium symporter activity	molecular function	GO:0015501	5	1	18094	48	SLC1A2
1.320e-02	-4.33	neurotrophin receptor activity	molecular function	GO:0005030	5	1	18094	48	NTRK2
1.320e-02	-4.33	syndecan binding	molecular function	GO:0045545	5	1	18094	48	TNC
1.324e-02	-4.32	PLCH1 (phospholipase C eta 1)	protein interactions	23007	68	2	19454	50	PARD3,NTRK2
1.332e-02	-4.32	human chr7q36.2	chromosome location	human chr7q36.2	7	1	26134	50	DPP6
1.332e-02	-4.32	human chr4q21.3	chromosome location	human chr4q21.3	7	1	26134	50	MAPK10
1.337e-02	-4.31	transport	biological process	GO:0006810	3615	17	18204	50	PITPNC1,SFXN5,SLC1A2,RYR3,NTRK2,ATP1A2,TRPM3,FMN2,PLCB1,SLC14A1,CAMK2G,GPM6A,KALRN,SLC4A4,MACF1,LRP1B,NRXN1
1.337e-02	-4.31	actin filament bundle assembly	biological process	GO:0051017	64	2	18204	50	FMN2,SORBS1
1.337e-02	-4.31	dendrite morphogenesis	biological process	GO:0048813	64	2	18204	50	CTNNA2,CTNND2
1.341e-02	-4.31	oesophagus-lower_third-carcinoma-adenocarcinoma	COSMIC cancer mutations	oesophagus-lower_third-carcinoma-adenocarcinoma	6302	26	16828	48	NEBL,RORA,TRPM3,MGAT4C,NTRK2,PARD3,SORBS1,CTNND2,NRG3,FAT3,TNC,RYR3,PLCB1,GPC5,MACF1,ADCY2,NAV3,DGKG,SYNE1,KALRN,FMN2,SOX5,NRXN1,CNTN1,LRP1B,DPP6
1.343e-02	-4.31	Vinculin/catenin	interpro domains	IPR006077	5	1	18521	50	CTNNA2
1.343e-02	-4.31	Na/HCO3_transpt	interpro domains	IPR003024	5	1	18521	50	SLC4A4
1.343e-02	-4.31	Mtc	interpro domains	IPR004686	5	1	18521	50	SFXN5
1.343e-02	-4.31	EGF_Tenascin	interpro domains	IPR041161	5	1	18521	50	TNC
1.343e-02	-4.31	PI_transfer	interpro domains	IPR001666	5	1	18521	50	PITPNC1
1.359e-02	-4.30	skin-head_neck-carcinoma-squamous_cell_carcinoma	COSMIC cancer mutations	skin-head_neck-carcinoma-squamous_cell_carcinoma	14191	46	16828	48	RYR3,NRG3,NKAIN3,NTM,FMN2,DTNA,HPSE2,DCLK2,NRXN1,CNTN1,DPP6,NTRK2,ATP1A2,TRPM3,PARD3,SLC4A4,SLC1A2,SORBS1,CTNND2,SFXN5,TNC,PLCB1,FAT3,NAV3,MACF1,GPC5,ADCY2,DGKG,KALRN,SYNE1,RFX4,CAMK2G,SOX5,TNIK,LRP1B,NEBL,NRCAM,LSAMP,RORA,MGAT4C,NAV2,GPM6A,ABLIM1,NHSL1,SLC14A1,PITPNC1
1.362e-02	-4.30	cell body	cellular component	GO:0044297	556	5	19108	49	ATP1A2,GPM6A,CTNND2,NRXN1,SLC1A2
1.365e-02	-4.29	cell adhesion mediator activity	molecular function	GO:0098631	67	2	18094	48	CNTN1,NRCAM
1.366e-02	-4.29	response to prostaglandin D	biological process	GO:0071798	5	1	18204	50	TNC
1.366e-02	-4.29	citrate transport	biological process	GO:0015746	5	1	18204	50	SFXN5
1.366e-02	-4.29	polar body extrusion after meiotic divisions	biological process	GO:0040038	5	1	18204	50	FMN2
1.366e-02	-4.29	synaptic signaling via neuropeptide	biological process	GO:0099538	5	1	18204	50	NTRK2
1.366e-02	-4.29	cellular response to prostaglandin D stimulus	biological process	GO:0071799	5	1	18204	50	TNC
1.366e-02	-4.29	activation of meiosis	biological process	GO:0090427	5	1	18204	50	PLCB1
1.366e-02	-4.29	D-aspartate import across plasma membrane	biological process	GO:0070779	5	1	18204	50	SLC1A2
1.366e-02	-4.29	tricarboxylic acid transport	biological process	GO:0006842	5	1	18204	50	SFXN5
1.366e-02	-4.29	gephyrin clustering involved in postsynaptic density assembly	biological process	GO:0097116	5	1	18204	50	NRXN1
1.366e-02	-4.29	glossopharyngeal nerve development	biological process	GO:0021563	5	1	18204	50	NAV2
1.366e-02	-4.29	D-aspartate transmembrane transport	biological process	GO:0070777	5	1	18204	50	SLC1A2
1.366e-02	-4.29	amygdala development	biological process	GO:0021764	5	1	18204	50	ATP1A2
1.369e-02	-4.29	Vinculin	pfam domains	PF01044	5	1	17795	49	CTNNA2
1.369e-02	-4.29	IP_trans	pfam domains	PF02121	5	1	17795	49	PITPNC1
1.369e-02	-4.29	EGF_Tenascin	pfam domains	PF18720	5	1	17795	49	TNC
1.369e-02	-4.29	SFXNs	pfam domains	PF03820	5	1	17795	49	SFXN5
1.377e-02	-4.29	regulation of dendrite morphogenesis	biological process	GO:0048814	65	2	18204	50	TNIK,SYNE1
1.377e-02	-4.29	positive regulation of synapse assembly	biological process	GO:0051965	65	2	18204	50	NRXN1,NTRK2
1.386e-02	-4.28	regulation of carbohydrate metabolic process	biological process	GO:0006109	183	3	18204	50	SORBS1,RORA,SLC4A4
1.389e-02	-4.28	regulation of Wnt signaling pathway	biological process	GO:0030111	339	4	18204	50	MACF1,GPC5,CTNND2,RBMS3
1.399e-02	-4.27	PCDH20 (protocadherin 20)	protein interactions	64881	70	2	19454	50	CTNNA2,MGAT4C
1.407e-02	-4.26	RAB35 (RAB35, member RAS oncogene family)	protein interactions	11021	559	5	19454	50	DTNA,PLCB1,MACF1,FMN2,PARD3
1.408e-02	-4.26	seminoma	COSMIC cancer mutations	seminoma	700	6	16828	48	DCLK2,CAMK2G,SYNE1,NTRK2,TNIK,CNTN1
1.418e-02	-4.26	retina morphogenesis in camera-type eye	biological process	GO:0060042	66	2	18204	50	NTRK2,FAT3
1.433e-02	-4.25	NEBU	smart domains	SM00227	4	1	9717	35	NEBL
1.433e-02	-4.25	KASH	smart domains	SM01249	4	1	9717	35	SYNE1
1.435e-02	-4.24	skin-ankle-malignant_melanoma-acral_lentiginous	COSMIC cancer mutations	skin-ankle-malignant_melanoma-acral_lentiginous	330	4	16828	48	PLCB1,NRG3,KALRN,PARD3
1.437e-02	-4.24	AKR7L (aldo-keto reductase family 7 like (gene/pseudogene))	protein interactions	246181	71	2	19454	50	PARD3,MACF1
1.451e-02	-4.23	NTRK3 (neurotrophic receptor tyrosine kinase 3)	protein interactions	4916	367	4	19454	50	PARD3,ABLIM1,TNIK,NTRK2
1.455e-02	-4.23	Corticotropin Activation of Cortisol Production	SMPDB pathways	SMP0000310	5	1	1369	4	ADCY2
1.470e-02	-4.22	central_nervous_system-medulla-primitive_neuroectodermal_tumour-medulloblastoma-large_cell	COSMIC cancer mutations	central_nervous_system-medulla-primitive_neuroectodermal_tumour-medulloblastoma-large_cell	14773	47	16828	48	LSAMP,RORA,NRCAM,NEBL,GPM6A,NAV2,MGAT4C,ABLIM1,PITPNC1,NHSL1,SLC14A1,GPC5,MACF1,ADCY2,NAV3,FAT3,TNC,PLCB1,SYNE1,KALRN,RFX4,MSI2,DGKG,SOX5,RBMS3,CAMK2G,LRP1B,TNIK,PARD3,TRPM3,NTRK2,ATP1A2,SORBS1,SLC4A4,SLC1A2,CTNND2,SFXN5,NRG3,RYR3,NTM,DTNA,FMN2,DCLK2,NRXN1,HPSE2,DPP6,CNTN1
1.470e-02	-4.22	central_nervous_system-medulla-primitive_neuroectodermal_tumour-medulloblastoma-classic	COSMIC cancer mutations	central_nervous_system-medulla-primitive_neuroectodermal_tumour-medulloblastoma-classic	14773	47	16828	48	ABLIM1,NHSL1,SLC14A1,PITPNC1,NRCAM,LSAMP,RORA,NEBL,NAV2,GPM6A,MGAT4C,CAMK2G,RBMS3,SOX5,LRP1B,TNIK,NAV3,ADCY2,MACF1,GPC5,PLCB1,TNC,FAT3,MSI2,RFX4,KALRN,SYNE1,DGKG,SORBS1,SLC1A2,SLC4A4,SFXN5,CTNND2,PARD3,ATP1A2,NTRK2,TRPM3,NRXN1,DCLK2,HPSE2,DPP6,CNTN1,RYR3,NRG3,FMN2,DTNA,NTM
1.470e-02	-4.22	central_nervous_system-medulla-primitive_neuroectodermal_tumour-medulloblastoma-desmoplastic	COSMIC cancer mutations	central_nervous_system-medulla-primitive_neuroectodermal_tumour-medulloblastoma-desmoplastic	14773	47	16828	48	NEBL,NRCAM,RORA,LSAMP,MGAT4C,NAV2,GPM6A,ABLIM1,SLC14A1,NHSL1,PITPNC1,PLCB1,TNC,FAT3,NAV3,ADCY2,MACF1,GPC5,DGKG,MSI2,RFX4,KALRN,SYNE1,CAMK2G,RBMS3,SOX5,TNIK,LRP1B,ATP1A2,NTRK2,TRPM3,PARD3,SLC1A2,SLC4A4,SORBS1,SFXN5,CTNND2,RYR3,NRG3,DTNA,FMN2,NTM,HPSE2,NRXN1,DCLK2,CNTN1,DPP6
1.470e-02	-4.22	central_nervous_system-medulla-primitive_neuroectodermal_tumour-medulloblastoma	COSMIC cancer mutations	central_nervous_system-medulla-primitive_neuroectodermal_tumour-medulloblastoma	14773	47	16828	48	NRG3,RYR3,NTM,DTNA,FMN2,HPSE2,DCLK2,NRXN1,CNTN1,DPP6,TRPM3,NTRK2,ATP1A2,PARD3,SLC4A4,SLC1A2,SORBS1,CTNND2,SFXN5,FAT3,TNC,PLCB1,GPC5,MACF1,ADCY2,NAV3,DGKG,SYNE1,KALRN,RFX4,MSI2,SOX5,RBMS3,CAMK2G,TNIK,LRP1B,NEBL,RORA,LSAMP,NRCAM,MGAT4C,GPM6A,NAV2,ABLIM1,PITPNC1,NHSL1,SLC14A1
1.474e-02	-4.22	classic	COSMIC cancer mutations	classic	14774	47	16828	48	NAV2,GPM6A,MGAT4C,NRCAM,RORA,LSAMP,NEBL,NHSL1,SLC14A1,PITPNC1,ABLIM1,MSI2,SYNE1,KALRN,RFX4,DGKG,NAV3,GPC5,MACF1,ADCY2,TNC,PLCB1,FAT3,LRP1B,TNIK,RBMS3,CAMK2G,SOX5,PARD3,NTRK2,ATP1A2,TRPM3,CTNND2,SFXN5,SORBS1,SLC4A4,SLC1A2,NTM,DTNA,FMN2,RYR3,NRG3,DPP6,CNTN1,DCLK2,NRXN1,HPSE2
1.476e-02	-4.22	DPYSL3 (dihydropyrimidinase like 3)	protein interactions	1809	72	2	19454	50	TNIK,GPM6A
1.476e-02	-4.22	Ppp1cb (protein phosphatase 1 catalytic subunit beta)	protein interactions	19046	72	2	19454	50	PARD3,ABLIM1
1.490e-02	-4.21	medulla	COSMIC cancer mutations	medulla	14778	47	16828	48	GPC5,MACF1,ADCY2,NAV3,FAT3,TNC,PLCB1,KALRN,SYNE1,RFX4,MSI2,DGKG,SOX5,RBMS3,CAMK2G,LRP1B,TNIK,LSAMP,RORA,NRCAM,NEBL,GPM6A,NAV2,MGAT4C,ABLIM1,PITPNC1,NHSL1,SLC14A1,NRG3,RYR3,NTM,DTNA,FMN2,DCLK2,NRXN1,HPSE2,DPP6,CNTN1,PARD3,TRPM3,NTRK2,ATP1A2,SORBS1,SLC4A4,SLC1A2,CTNND2,SFXN5
1.495e-02	-4.20	desmoplastic	COSMIC cancer mutations	desmoplastic	14779	47	16828	48	SLC4A4,SLC1A2,SORBS1,CTNND2,SFXN5,NTRK2,ATP1A2,TRPM3,PARD3,HPSE2,DCLK2,NRXN1,CNTN1,DPP6,RYR3,NRG3,NTM,FMN2,DTNA,ABLIM1,SLC14A1,NHSL1,PITPNC1,NEBL,NRCAM,RORA,LSAMP,MGAT4C,NAV2,GPM6A,RBMS3,CAMK2G,SOX5,TNIK,LRP1B,TNC,PLCB1,FAT3,NAV3,MACF1,GPC5,ADCY2,DGKG,MSI2,KALRN,SYNE1,RFX4
1.498e-02	-4.20	NGF-independant TRKA activation	REACTOME pathways	R-HSA-187024	5	1	10285	31	NTRK2
1.501e-02	-4.20	actin filament bundle organization	biological process	GO:0061572	68	2	18204	50	SORBS1,FMN2
1.511e-02	-4.19	-	gene3d domains	6.10.140.620	5	1	14470	44	CAMK2G
1.526e-02	-4.18	cellular response to lipid	biological process	GO:0071396	534	5	18204	50	ATP1A2,ADCY2,RORA,TNC,PLCB1
1.526e-02	-4.18	large_intestine-caecum-carcinoma-adenocarcinoma	COSMIC cancer mutations	large_intestine-caecum-carcinoma-adenocarcinoma	14236	46	16828	48	SORBS1,SLC4A4,SLC1A2,CTNND2,SFXN5,PARD3,TRPM3,NTRK2,ATP1A2,DCLK2,NRXN1,HPSE2,DPP6,CNTN1,NKAIN3,NRG3,RYR3,NTM,FMN2,DTNA,ABLIM1,PITPNC1,NHSL1,SLC14A1,LSAMP,RORA,NRCAM,NEBL,GPM6A,NAV2,MGAT4C,SOX5,CAMK2G,LRP1B,TNIK,MACF1,GPC5,ADCY2,NAV3,FAT3,TNC,PLCB1,KALRN,SYNE1,RFX4,DGKG
1.529e-02	-4.18	PAR polarity complex	cellular component	GO:0120157	6	1	19108	49	PARD3
1.531e-02	-4.18	protein localization	biological process	GO:0008104	1954	11	18204	50	DCLK2,MACF1,NRXN1,TNIK,LRP1B,FMN2,SYNE1,DPP6,CAMK2G,NRCAM,PARD3
1.531e-02	-4.18	pallium development	biological process	GO:0021543	190	3	18204	50	PLCB1,NTRK2,DCLK2
1.532e-02	-4.18	Zbtb2 (zinc finger and BTB domain containing 2)	protein interactions	381990	6	1	19454	50	SORBS1
1.532e-02	-4.18	SLC12A5 (solute carrier family 12 member 5)	protein interactions	57468	6	1	19454	50	GPM6A
1.532e-02	-4.18	DRP2 (dystrophin related protein 2)	protein interactions	1821	6	1	19454	50	DTNA
1.532e-02	-4.18	SYTL3 (synaptotagmin like 3)	protein interactions	94120	6	1	19454	50	NRXN1
1.532e-02	-4.18	SOX11 (SRY-box transcription factor 11)	protein interactions	6664	6	1	19454	50	SOX5
1.532e-02	-4.18	Rara (retinoic acid receptor, alpha)	protein interactions	19401	6	1	19454	50	MAPK10
1.532e-02	-4.18	SOX1 (SRY-box transcription factor 1)	protein interactions	6656	6	1	19454	50	SOX5
1.532e-02	-4.18	CIBAR2 (CBY1 interacting BAR domain containing 2)	protein interactions	339145	6	1	19454	50	CAMK2G
1.532e-02	-4.18	Tiam2 (T cell lymphoma invasion and metastasis 2)	protein interactions	24001	6	1	19454	50	DTNA
1.532e-02	-4.18	ADCY1 (adenylate cyclase 1)	protein interactions	107	6	1	19454	50	ADCY2
1.532e-02	-4.18	SMOC2 (SPARC related modular calcium binding 2)	protein interactions	64094	6	1	19454	50	TNC
1.532e-02	-4.18	CYRIA (CYFIP related Rac1 interactor A)	protein interactions	81553	6	1	19454	50	GPM6A
1.532e-02	-4.18	SPATA4 (spermatogenesis associated 4)	protein interactions	132851	6	1	19454	50	FAT3
1.535e-02	-4.18	Immunoglobulin	interpro domains	IPR013151	70	2	18521	50	NTM,CNTN1
1.550e-02	-4.17	LIM	pfam domains	PF00412	69	2	17795	49	NEBL,ABLIM1
1.552e-02	-4.17	CASK (calcium/calmodulin dependent serine protein kinase)	protein interactions	8573	204	3	19454	50	NRXN1,ABLIM1,DTNA
1.554e-02	-4.16	central_nervous_system-brainstem-glioma	COSMIC cancer mutations	central_nervous_system-brainstem-glioma	338	4	16828	48	TNC,HPSE2,GPC5,LRP1B
1.566e-02	-4.16	haematopoietic_and_lymphoid_tissue-soft_tissue-lymphoid_neoplasm-diffuse_large_B_cell_lymphoma	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue-soft_tissue-lymphoid_neoplasm-diffuse_large_B_cell_lymphoma	67	2	16828	48	LRP1B,SYNE1
1.573e-02	-4.15	caecum	COSMIC cancer mutations	caecum	14248	46	16828	48	TRPM3,ATP1A2,NTRK2,PARD3,SLC1A2,SLC4A4,SORBS1,SFXN5,CTNND2,NRG3,RYR3,NKAIN3,FMN2,DTNA,NTM,HPSE2,NRXN1,DCLK2,CNTN1,DPP6,NEBL,RORA,LSAMP,NRCAM,MGAT4C,GPM6A,NAV2,ABLIM1,PITPNC1,NHSL1,SLC14A1,FAT3,PLCB1,TNC,ADCY2,GPC5,MACF1,NAV3,DGKG,RFX4,SYNE1,KALRN,SOX5,CAMK2G,TNIK,LRP1B
1.575e-02	-4.15	cellular macromolecule localization	biological process	GO:0070727	1962	11	18204	50	DCLK2,MACF1,TNIK,LRP1B,NRXN1,SYNE1,FMN2,DPP6,CAMK2G,NRCAM,PARD3
1.576e-02	-4.15	Znf_LIM	interpro domains	IPR001781	71	2	18521	50	ABLIM1,NEBL
1.581e-02	-4.15	steroid hormone binding	molecular function	GO:1990239	6	1	18094	48	ATP1A2
1.581e-02	-4.15	calcium-induced calcium release activity	molecular function	GO:0048763	6	1	18094	48	RYR3
1.581e-02	-4.15	sodium:bicarbonate symporter activity	molecular function	GO:0008510	6	1	18094	48	SLC4A4
1.589e-02	-4.14	ovary-carcinoma	COSMIC cancer mutations	ovary-carcinoma	933	7	16828	48	SYNE1,ATP1A2,TNIK,NTRK2,MACF1,CAMK2G,DCLK2
1.592e-02	-4.14	ig	pfam domains	PF00047	70	2	17795	49	NTM,CNTN1
1.609e-02	-4.13	G3BP1 (G3BP stress granule assembly factor 1)	protein interactions	10146	799	6	19454	50	MACF1,MSI2,SOX5,SORBS1,CTNNA2,SYNE1
1.609e-02	-4.13	Glypican_CS	interpro domains	IPR019803	6	1	18521	50	GPC5
1.609e-02	-4.13	Ryanodine_IP3_receptor	interpro domains	IPR015925	6	1	18521	50	RYR3
1.609e-02	-4.13	Adcy_conserved_dom	interpro domains	IPR009398	6	1	18521	50	ADCY2
1.609e-02	-4.13	EF-hand_dom_typ1	interpro domains	IPR015153	6	1	18521	50	DTNA
1.609e-02	-4.13	GAR_dom	interpro domains	IPR003108	6	1	18521	50	MACF1
1.609e-02	-4.13	Glypican	interpro domains	IPR001863	6	1	18521	50	GPC5
1.609e-02	-4.13	GAR_dom_sf	interpro domains	IPR036534	6	1	18521	50	MACF1
1.609e-02	-4.13	Peptidase_S9B_N	interpro domains	IPR002469	6	1	18521	50	DPP6
1.609e-02	-4.13	RIH_dom	interpro domains	IPR000699	6	1	18521	50	RYR3
1.609e-02	-4.13	Desmoplakin_SH3	interpro domains	IPR041615	6	1	18521	50	MACF1
1.609e-02	-4.13	Syndecan/Neurexin_dom	interpro domains	IPR027789	6	1	18521	50	NRXN1
1.609e-02	-4.13	P-type_ATPase_IIC	interpro domains	IPR005775	6	1	18521	50	ATP1A2
1.609e-02	-4.13	RyR/IP3R_RIH_dom_sf	interpro domains	IPR035910	6	1	18521	50	RYR3
1.609e-02	-4.13	RIH_assoc-dom	interpro domains	IPR013662	6	1	18521	50	RYR3
1.609e-02	-4.13	EF-hand_dom_typ2	interpro domains	IPR015154	6	1	18521	50	DTNA
1.609e-02	-4.13	Ins145_P3_rcpt	interpro domains	IPR014821	6	1	18521	50	RYR3
1.615e-02	-4.13	prostate-carcinoma-adenocarcinoma	COSMIC cancer mutations	prostate-carcinoma-adenocarcinoma	12379	42	16828	48	LRP1B,DPP6,TNIK,CNTN1,NRXN1,SOX5,HPSE2,NTM,FMN2,KALRN,SYNE1,RFX4,DGKG,NKAIN3,NAV3,GPC5,MACF1,ADCY2,TNC,PLCB1,RYR3,NRG3,FAT3,CTNND2,SFXN5,SLC14A1,NHSL1,PITPNC1,SORBS1,ABLIM1,SLC1A2,NAV2,GPM6A,PARD3,MGAT4C,NTRK2,ATP1A2,TRPM3,NRCAM,RORA,LSAMP,NEBL
1.616e-02	-4.13	PITRANSFER	prints domains	PR00391	5	1	5227	17	PITPNC1
1.616e-02	-4.13	NAHCO3TRSPRT	prints domains	PR01232	5	1	5227	17	SLC4A4
1.627e-02	-4.12	sarcoplasmic reticulum	cellular component	GO:0016529	76	2	19108	49	CAMK2G,RYR3
1.629e-02	-4.12	MKRN2 (makorin ring finger protein 2)	protein interactions	23609	380	4	19454	50	NRCAM,MACF1,PARD3,CNTN1
1.633e-02	-4.11	RYK (receptor like tyrosine kinase)	protein interactions	6259	208	3	19454	50	CNTN1,FAT3,CTNNA2
1.637e-02	-4.11	asymmetric neuroblast division	biological process	GO:0055059	6	1	18204	50	SOX5
1.637e-02	-4.11	mammary gland formation	biological process	GO:0060592	6	1	18204	50	NRG3
1.637e-02	-4.11	postsynaptic density protein 95 clustering	biological process	GO:0097119	6	1	18204	50	NRXN1
1.637e-02	-4.11	ERBB4-ERBB4 signaling pathway	biological process	GO:0038138	6	1	18204	50	NRG3
1.637e-02	-4.11	L-aspartate import across plasma membrane	biological process	GO:0140009	6	1	18204	50	SLC1A2
1.637e-02	-4.11	imitative learning	biological process	GO:0098596	6	1	18204	50	NRXN1
1.637e-02	-4.11	inositol trisphosphate metabolic process	biological process	GO:0032957	6	1	18204	50	PLCB1
1.637e-02	-4.11	D-amino acid transport	biological process	GO:0042940	6	1	18204	50	SLC1A2
1.637e-02	-4.11	establishment of meiotic spindle localization	biological process	GO:0051295	6	1	18204	50	FMN2
1.637e-02	-4.11	vocal learning	biological process	GO:0042297	6	1	18204	50	NRXN1
1.637e-02	-4.11	cellular response to ether	biological process	GO:0071362	6	1	18204	50	PLCB1
1.637e-02	-4.11	clustering of voltage-gated sodium channels	biological process	GO:0045162	6	1	18204	50	NRCAM
1.641e-02	-4.11	Plectin	pfam domains	PF00681	6	1	17795	49	MACF1
1.641e-02	-4.11	GAS2	pfam domains	PF02187	6	1	17795	49	MACF1
1.641e-02	-4.11	Syndecan	pfam domains	PF01034	6	1	17795	49	NRXN1
1.641e-02	-4.11	Ins145_P3_rec	pfam domains	PF08709	6	1	17795	49	RYR3
1.641e-02	-4.11	EF-hand_3	pfam domains	PF09069	6	1	17795	49	DTNA
1.641e-02	-4.11	Adcy_cons_dom	pfam domains	PF06327	6	1	17795	49	ADCY2
1.641e-02	-4.11	RYDR_ITPR	pfam domains	PF01365	6	1	17795	49	RYR3
1.641e-02	-4.11	EF-hand_2	pfam domains	PF09068	6	1	17795	49	DTNA
1.641e-02	-4.11	DPPIV_N	pfam domains	PF00930	6	1	17795	49	DPP6
1.641e-02	-4.11	SH3_10	pfam domains	PF17902	6	1	17795	49	MACF1
1.641e-02	-4.11	RIH_assoc	pfam domains	PF08454	6	1	17795	49	RYR3
1.641e-02	-4.11	Glypican	pfam domains	PF01153	6	1	17795	49	GPC5
1.650e-02	-4.10	cGMP-PKG signaling pathway	KEGG pathways	hsa04022	163	3	7161	24	ATP1A2,ADCY2,PLCB1
1.650e-02	-4.10	cGMP-PKG signaling pathway	KEGG pathways	ko04022	163	3	7161	24	ATP1A2,ADCY2,PLCB1
1.654e-02	-4.10	MACF1 (microtubule actin crosslinking factor 1)	protein interactions	23499	209	3	19454	50	NRXN1,TNIK,NRCAM
1.676e-02	-4.09	ADGRL2 (adhesion G protein-coupled receptor L2)	protein interactions	23266	77	2	19454	50	PARD3,NTRK2
1.685e-02	-4.08	locomotory behavior	biological process	GO:0007626	197	3	18204	50	CNTN1,ATP1A2,NAV2
1.685e-02	-4.08	protein localization to plasma membrane	biological process	GO:0072659	197	3	18204	50	DPP6,MACF1,TNIK
1.694e-02	-4.08	signal transduction	biological process	GO:0007165	4637	20	18204	50	DTNA,DGKG,NRG3,KALRN,TNIK,MACF1,RORA,MAPK10,ADCY2,CNTN1,PITPNC1,RYR3,PARD3,ATP1A2,NTRK2,DCLK2,CTNND2,PLCB1,SORBS1,FMN2
1.700e-02	-4.07	autonomic_ganglia-paraganglioma-benign	COSMIC cancer mutations	autonomic_ganglia-paraganglioma-benign	6	1	16828	48	NHSL1
1.700e-02	-4.07	localization within membrane	biological process	GO:0051668	549	5	18204	50	MACF1,TNIK,NRXN1,PARD3,DPP6
1.711e-02	-4.07	positive regulation of cell projection organization	biological process	GO:0031346	361	4	18204	50	NTRK2,GPM6A,MACF1,CNTN1
1.717e-02	-4.06	ANKRD40 (ankyrin repeat domain 40)	protein interactions	91369	78	2	19454	50	MSI2,SOX5
1.727e-02	-4.06	Human Thyroid Stimulating Hormone (TSH) signaling pathway	WikiPathways	WP2032	68	2	5310	16	PLCB1,ADCY2
1.728e-02	-4.06	calmodulin binding	molecular function	GO:0005516	206	3	18094	48	CAMK2G,PLCB1,RYR3
1.731e-02	-4.06	testis	COSMIC cancer mutations	testis	733	6	16828	48	NTRK2,TNIK,SYNE1,MACF1,DCLK2,CAMK2G
1.740e-02	-4.05	Phenytoin (Antiarrhythmic) Action Pathway	SMPDB pathways	SMP0000327	77	2	1369	4	ATP1A2,PLCB1
1.744e-02	-4.05	Dopamine Activation of Neurological Reward System	SMPDB pathways	SMP0000308	6	1	1369	4	ADCY2
1.744e-02	-4.05	Phospholipase C Signaling Pathway	SMPDB pathways	SMP0063783	6	1	1369	4	PLCB1
1.744e-02	-4.05	Intracellular Signalling Through PGD2 receptor and Prostaglandin D2	SMPDB pathways	SMP0000343	6	1	1369	4	ADCY2
1.747e-02	-4.05	small molecule binding	molecular function	GO:0036094	6197	24	18094	48	NAV3,KALRN,PLCB1,MGAT4C,NTRK2,ADCY2,NAV2,NRXN1,PITPNC1,LRP1B,MAPK10,PARD3,MACF1,FAT3,RYR3,DTNA,ABLIM1,DCLK2,CAMK2G,TNIK,RORA,DGKG,ATP1A2,SLC1A2
1.761e-02	-4.04	NCK1 (NCK adaptor protein 1)	protein interactions	4690	214	3	19454	50	TNIK,NTRK2,NHSL1
1.765e-02	-4.04	animal organ morphogenesis	biological process	GO:0009887	988	7	18204	50	TNC,SOX5,NTRK2,NRG3,ABLIM1,CTNNA2,FAT3
1.782e-02	-4.03	dendritic spine head	cellular component	GO:0044327	7	1	19108	49	SYNE1
1.786e-02	-4.03	Nde1 (nudE neurodevelopment protein 1)	protein interactions	67203	7	1	19454	50	SYNE1
1.786e-02	-4.03	SSX6P (SSX family member 6, pseudogene)	protein interactions	280657	7	1	19454	50	FAT3
1.791e-02	-4.02	monoatomic cation transport	biological process	GO:0006812	766	6	18204	50	SLC4A4,GPM6A,ATP1A2,TRPM3,PLCB1,RYR3
1.793e-02	-4.02	large_cell	COSMIC cancer mutations	large_cell	14845	47	16828	48	LSAMP,RORA,NRCAM,NEBL,GPM6A,NAV2,MGAT4C,ABLIM1,PITPNC1,NHSL1,SLC14A1,ADCY2,GPC5,MACF1,NAV3,FAT3,PLCB1,TNC,RFX4,KALRN,SYNE1,MSI2,DGKG,SOX5,CAMK2G,RBMS3,LRP1B,TNIK,PARD3,TRPM3,ATP1A2,NTRK2,SORBS1,SLC1A2,SLC4A4,SFXN5,CTNND2,NRG3,RYR3,FMN2,DTNA,NTM,NRXN1,DCLK2,HPSE2,DPP6,CNTN1
1.794e-02	-4.02	adrenal_gland-adrenal_gland-adrenal_cortical_adenoma-cortisol_producing	COSMIC cancer mutations	adrenal_gland-adrenal_gland-adrenal_cortical_adenoma-cortisol_producing	72	2	16828	48	FMN2,LRP1B
1.794e-02	-4.02	cortisol_producing	COSMIC cancer mutations	cortisol_producing	72	2	16828	48	LRP1B,FMN2
1.795e-02	-4.02	Activation of TRKA receptors	REACTOME pathways	R-HSA-187015	6	1	10285	31	NTRK2
1.811e-02	-4.01	IP3 receptor type 1 binding core, RIH domain	gene3d domains	1.25.10.30	6	1	14470	44	RYR3
1.811e-02	-4.01	Gas2-like domain	gene3d domains	3.30.920.20	6	1	14470	44	MACF1
1.811e-02	-4.01	Dipeptidylpeptidase IV, N-terminal domain	gene3d domains	2.140.10.30	6	1	14470	44	DPP6
1.811e-02	-4.01	Plakin repeat	gene3d domains	3.90.1290.10	6	1	14470	44	MACF1
1.814e-02	-4.01	acute_lymphoblastic_leukaemia	COSMIC cancer mutations	acute_lymphoblastic_leukaemia	2197	12	16828	48	ADCY2,DTNA,SYNE1,KALRN,NTRK2,ATP1A2,DCLK2,CAMK2G,SOX5,SLC4A4,LRP1B,TNIK
1.826e-02	-4.00	GFAP (glial fibrillary acidic protein)	protein interactions	2670	217	3	19454	50	RORA,ABLIM1,NKAIN3
1.836e-02	-4.00	sarcomere	cellular component	GO:0030017	218	3	19108	49	NEBL,RYR3,SYNE1
1.843e-02	-3.99	P-type sodium transporter activity	molecular function	GO:0008554	7	1	18094	48	ATP1A2
1.843e-02	-3.99	phosphatidic acid transfer activity	molecular function	GO:1990050	7	1	18094	48	PITPNC1
1.843e-02	-3.99	P-type sodium:potassium-exchanging transporter activity	molecular function	GO:0005391	7	1	18094	48	ATP1A2
1.843e-02	-3.99	calcium-dependent protein serine/threonine phosphatase activity	molecular function	GO:0004723	7	1	18094	48	CAMK2G
1.851e-02	-3.99	upper_aerodigestive_tract-head_neck-carcinoma-squamous_cell_carcinoma	COSMIC cancer mutations	upper_aerodigestive_tract-head_neck-carcinoma-squamous_cell_carcinoma	9263	34	16828	48	SLC4A4,SORBS1,PITPNC1,NHSL1,CTNND2,NEBL,LSAMP,RORA,TRPM3,ATP1A2,MGAT4C,NTRK2,NAV2,HPSE2,SOX5,CAMK2G,DCLK2,TNIK,CNTN1,LRP1B,FAT3,RYR3,PLCB1,TNC,ADCY2,MACF1,GPC5,NAV3,NKAIN3,DGKG,KALRN,SYNE1,FMN2,MSI2
1.852e-02	-3.99	regulation of axon extension	biological process	GO:0030516	76	2	18204	50	NRCAM,MACF1
1.875e-02	-3.98	Plectin_repeat	interpro domains	IPR001101	7	1	18521	50	MACF1
1.875e-02	-3.98	Plakophilin/d_Catenin	interpro domains	IPR028435	7	1	18521	50	CTNND2
1.875e-02	-3.98	Na-dicarboxylate_symporter_CS	interpro domains	IPR018107	7	1	18521	50	SLC1A2
1.875e-02	-3.98	Alpha-catenin/vinculin-like_sf	interpro domains	IPR036723	7	1	18521	50	CTNNA2
1.875e-02	-3.98	Na-dicarboxylate_symporter	interpro domains	IPR001991	7	1	18521	50	SLC1A2
1.875e-02	-3.98	Ammonium/urea_transptr	interpro domains	IPR029020	7	1	18521	50	SLC14A1
1.875e-02	-3.98	Na:dicarbo_symporter_sf	interpro domains	IPR036458	7	1	18521	50	SLC1A2
1.875e-02	-3.98	Hud_Sxl_RNA	interpro domains	IPR002343	7	1	18521	50	RBMS3
1.875e-02	-3.98	Plakin_repeat_sf	interpro domains	IPR035915	7	1	18521	50	MACF1
1.898e-02	-3.96	cellular response to interleukin-1	biological process	GO:0071347	77	2	18204	50	RORA,PLCB1
1.898e-02	-3.96	regulation of synaptic transmission, glutamatergic	biological process	GO:0051966	77	2	18204	50	NRXN1,ATP1A2
1.898e-02	-3.96	positive regulation of axonogenesis	biological process	GO:0050772	77	2	18204	50	NTRK2,MACF1
1.905e-02	-3.96	kidney-Wilms_tumour	COSMIC cancer mutations	kidney-Wilms_tumour	545	5	16828	48	DCLK2,FMN2,CAMK2G,NTRK2,TNIK
1.907e-02	-3.96	observational learning	biological process	GO:0098597	7	1	18204	50	NRXN1
1.907e-02	-3.96	interneuron migration from the subpallium to the cortex	biological process	GO:0021830	7	1	18204	50	NRG3
1.907e-02	-3.96	cellular response to magnesium ion	biological process	GO:0071286	7	1	18204	50	RYR3
1.907e-02	-3.96	chromosome movement towards spindle pole	biological process	GO:0051305	7	1	18204	50	FMN2
1.907e-02	-3.96	negative regulation of Arp2/3 complex-mediated actin nucleation	biological process	GO:0034316	7	1	18204	50	CTNNA2
1.907e-02	-3.96	peripheral nervous system axon regeneration	biological process	GO:0014012	7	1	18204	50	TNC
1.907e-02	-3.96	parallel actin filament bundle assembly	biological process	GO:0030046	7	1	18204	50	FMN2
1.907e-02	-3.96	regulation of monocyte extravasation	biological process	GO:2000437	7	1	18204	50	PLCB1
1.909e-02	-3.96	solute:sodium symporter activity	molecular function	GO:0015370	80	2	18094	48	SLC4A4,SLC1A2
1.912e-02	-3.96	SDF	pfam domains	PF00375	7	1	17795	49	SLC1A2
1.919e-02	-3.95	Wilms_tumour	COSMIC cancer mutations	Wilms_tumour	546	5	16828	48	DCLK2,FMN2,CAMK2G,NTRK2,TNIK
1.921e-02	-3.95	caveola	cellular component	GO:0005901	83	2	19108	49	ATP1A2,SORBS1
1.930e-02	-3.95	SYT1 (synaptotagmin 1)	protein interactions	6857	83	2	19454	50	GPM6A,NRXN1
1.939e-02	-3.94	YWHAQ (tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein theta)	protein interactions	10971	1076	7	19454	50	SORBS1,PARD3,ABLIM1,NHSL1,NAV2,DCLK2,MACF1
1.944e-02	-3.94	positive regulation of carbohydrate metabolic process	biological process	GO:0045913	78	2	18204	50	SORBS1,SLC4A4
1.944e-02	-3.94	regulation of glucose transmembrane transport	biological process	GO:0010827	78	2	18204	50	SORBS1,SLC1A2
1.944e-02	-3.94	dicarboxylic acid transport	biological process	GO:0006835	78	2	18204	50	SLC1A2,NTRK2
1.954e-02	-3.94	SH3-like_dom_sf	interpro domains	IPR036028	212	3	18521	50	NEBL,KALRN,SORBS1
1.954e-02	-3.94	GLYPICAN	prosite domains	PS01207	6	1	12186	40	GPC5
1.954e-02	-3.94	GAR	prosite domains	PS51460	6	1	12186	40	MACF1
1.960e-02	-3.93	skin-leg-malignant_melanoma	COSMIC cancer mutations	skin-leg-malignant_melanoma	549	5	16828	48	PLCB1,NRG3,NEBL,SYNE1,LRP1B
1.961e-02	-3.93	G alpha (q) signalling events	REACTOME pathways	R-HSA-416476	192	3	10285	31	KALRN,DGKG,PLCB1
1.962e-02	-3.93	Axon guidance	KEGG pathways	ko04360	174	3	7161	24	ABLIM1,PARD3,CAMK2G
1.962e-02	-3.93	Axon guidance	KEGG pathways	hsa04360	174	3	7161	24	PARD3,CAMK2G,ABLIM1
1.966e-02	-3.93	eye-uveal_tract-malignant_melanoma-spindle	COSMIC cancer mutations	eye-uveal_tract-malignant_melanoma-spindle	363	4	16828	48	KALRN,MACF1,CTNND2,TRPM3
1.980e-02	-3.92	regulation of system process	biological process	GO:0044057	571	5	18204	50	PARD3,SYNE1,NRXN1,ATP1A2,CAMK2G
1.991e-02	-3.92	FGFR1 (fibroblast growth factor receptor 1)	protein interactions	2260	611	5	19454	50	PARD3,TNIK,ABLIM1,DTNA,NHSL1
2.015e-02	-3.90	skin-upper_arm-malignant_melanoma	COSMIC cancer mutations	skin-upper_arm-malignant_melanoma	553	5	16828	48	LRP1B,SYNE1,FMN2,SLC4A4,PLCB1
2.032e-02	-3.90	Vasopressin Regulation of Water Homeostasis	SMPDB pathways	SMP0000322	7	1	1369	4	ADCY2
2.032e-02	-3.90	G-Protein Signaling Through Tubby Proteins	SMPDB pathways	SMP0089843	7	1	1369	4	PLCB1
2.034e-02	-3.90	zonula adherens	cellular component	GO:0005915	8	1	19108	49	SORBS1
2.038e-02	-3.89	LHB (luteinizing hormone subunit beta)	protein interactions	3972	8	1	19454	50	NTM
2.038e-02	-3.89	INSM1 (INSM transcriptional repressor 1)	protein interactions	3642	8	1	19454	50	SORBS1
2.038e-02	-3.89	CARD16 (caspase recruitment domain family member 16)	protein interactions	114769	8	1	19454	50	FAT3
2.055e-02	-3.88	PRKCD (protein kinase C delta)	protein interactions	5580	227	3	19454	50	MACF1,CAMK2G,PLCB1
2.063e-02	-3.88	SYNJ1 (synaptojanin 1)	protein interactions	8867	86	2	19454	50	SORBS1,GPM6A
2.063e-02	-3.88	FAM171A1 (family with sequence similarity 171 member A1)	protein interactions	221061	86	2	19454	50	NTRK2,PARD3
2.072e-02	-3.88	Cysteine Rich Protein	gene3d domains	2.10.110.10	73	2	14470	44	ABLIM1,NEBL
2.085e-02	-3.87	Long-term potentiation	KEGG pathways	hsa04720	67	2	7161	24	PLCB1,CAMK2G
2.085e-02	-3.87	Long-term potentiation	KEGG pathways	ko04720	67	2	7161	24	CAMK2G,PLCB1
2.091e-02	-3.87	NrCAM interactions	REACTOME pathways	R-HSA-447038	7	1	10285	31	NRCAM
2.092e-02	-3.87	phosphatidylinositol-4,5-bisphosphate binding	molecular function	GO:0005546	84	2	18094	48	PLCB1,PARD3
2.101e-02	-3.86	EF_hand_dom	interpro domains	IPR002048	218	3	18521	50	MACF1,DGKG,RYR3
2.103e-02	-3.86	PCNT (pericentrin)	protein interactions	5116	229	3	19454	50	MACF1,KALRN,SYNE1
2.103e-02	-3.86	P-type potassium transmembrane transporter activity	molecular function	GO:0008556	8	1	18094	48	ATP1A2
2.103e-02	-3.86	sodium ion binding	molecular function	GO:0031402	8	1	18094	48	ATP1A2
2.103e-02	-3.86	urea transmembrane transporter activity	molecular function	GO:0015204	8	1	18094	48	SLC14A1
2.110e-02	-3.86	Ammonium transporter AmtB like domains	gene3d domains	1.10.3430.10	7	1	14470	44	SLC14A1
2.110e-02	-3.86	Sodium:dicarboxylate symporter	gene3d domains	1.10.3860.10	7	1	14470	44	SLC1A2
2.122e-02	-3.85	regulation of response to stimulus	biological process	GO:0048583	4104	18	18204	50	CTNNA2,MAPK10,CTNND2,NTRK2,SYNE1,RBMS3,FMN2,SORBS1,PLCB1,DGKG,CAMK2G,KALRN,RORA,GPC5,MACF1,TNIK,NRXN1,TNC
2.127e-02	-3.85	ConA-like_dom_sf	interpro domains	IPR013320	219	3	18521	50	FAT3,RYR3,NRXN1
2.130e-02	-3.85	nucleotide binding	molecular function	GO:0000166	2128	11	18094	48	KALRN,DCLK2,MAPK10,NAV3,ATP1A2,CAMK2G,TNIK,DGKG,NTRK2,NAV2,ADCY2
2.137e-02	-3.85	nucleoside phosphate binding	molecular function	GO:1901265	2129	11	18094	48	DCLK2,ATP1A2,KALRN,NAV2,ADCY2,NAV3,NTRK2,DGKG,TNIK,CAMK2G,MAPK10
2.140e-02	-3.84	Adcy	interpro domains	IPR030672	8	1	18521	50	ADCY2
2.140e-02	-3.84	TRPM_SLOG	interpro domains	IPR041491	8	1	18521	50	TRPM3
2.140e-02	-3.84	RFX-like	interpro domains	IPR039779	8	1	18521	50	RFX4
2.140e-02	-3.84	Villin_headpiece_dom_sf	interpro domains	IPR036886	8	1	18521	50	ABLIM1
2.140e-02	-3.84	Plakin	interpro domains	IPR043197	8	1	18521	50	MACF1
2.140e-02	-3.84	Villin_headpiece	interpro domains	IPR003128	8	1	18521	50	ABLIM1
2.140e-02	-3.84	AC_N	interpro domains	IPR032628	8	1	18521	50	ADCY2
2.142e-02	-3.84	GAS2	smart domains	SM00243	6	1	9717	35	MACF1
2.157e-02	-3.84	FYN (FYN proto-oncogene, Src family tyrosine kinase)	protein interactions	2534	414	4	19454	50	NTRK2,KALRN,CNTN1,CTNND2
2.172e-02	-3.83	regulation of cell junction assembly	biological process	GO:1901888	217	3	18204	50	NRXN1,MACF1,NTRK2
2.177e-02	-3.83	central nervous system myelin formation	biological process	GO:0032289	8	1	18204	50	CNTN1
2.177e-02	-3.83	ERBB4 signaling pathway	biological process	GO:0038130	8	1	18204	50	NRG3
2.177e-02	-3.83	phospholipase C-activating G protein-coupled acetylcholine receptor signaling pathway	biological process	GO:0007207	8	1	18204	50	PLCB1
2.177e-02	-3.83	cell proliferation in external granule layer	biological process	GO:0021924	8	1	18204	50	RORA
2.177e-02	-3.83	cell proliferation in hindbrain	biological process	GO:0021534	8	1	18204	50	RORA
2.177e-02	-3.83	cellular response to vasopressin	biological process	GO:1904117	8	1	18204	50	PLCB1
2.177e-02	-3.83	regulation of synapse structural plasticity	biological process	GO:0051823	8	1	18204	50	CTNNA2
2.177e-02	-3.83	ion channel modulating, G protein-coupled receptor signaling pathway	biological process	GO:0099105	8	1	18204	50	PLCB1
2.177e-02	-3.83	regulation of L-glutamate import across plasma membrane	biological process	GO:0002036	8	1	18204	50	ATP1A2
2.177e-02	-3.83	response to vasopressin	biological process	GO:1904116	8	1	18204	50	PLCB1
2.177e-02	-3.83	cerebellar granule cell precursor proliferation	biological process	GO:0021930	8	1	18204	50	RORA
2.177e-02	-3.83	negative regulation of dendrite development	biological process	GO:2000171	8	1	18204	50	FAT3
2.177e-02	-3.83	meiotic cytokinesis	biological process	GO:0033206	8	1	18204	50	FMN2
2.182e-02	-3.82	LSDAT_euk	pfam domains	PF18139	8	1	17795	49	TRPM3
2.182e-02	-3.82	DCX	pfam domains	PF03607	8	1	17795	49	DCLK2
2.182e-02	-3.82	AC_N	pfam domains	PF16214	8	1	17795	49	ADCY2
2.182e-02	-3.82	VHP	pfam domains	PF02209	8	1	17795	49	ABLIM1
2.196e-02	-3.82	skin-leg-malignant_melanoma-superficial_spreading	COSMIC cancer mutations	skin-leg-malignant_melanoma-superficial_spreading	210	3	16828	48	NTM,LRP1B,SLC4A4
2.208e-02	-3.81	Chemokine signaling pathway	KEGG pathways	ko04062	182	3	7161	24	PLCB1,PARD3,ADCY2
2.208e-02	-3.81	Chemokine signaling pathway	KEGG pathways	hsa04062	182	3	7161	24	PARD3,ADCY2,PLCB1
2.224e-02	-3.81	glial cell differentiation	biological process	GO:0010001	219	3	18204	50	CNTN1,NTRK2,PARD3
2.224e-02	-3.81	bone-fibula-Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour	COSMIC cancer mutations	bone-fibula-Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour	377	4	16828	48	MACF1,SYNE1,NRXN1,TRPM3
2.233e-02	-3.80	peripheral nervous system development	biological process	GO:0007422	84	2	18204	50	PARD3,NTRK2
2.234e-02	-3.80	single-stranded RNA binding	molecular function	GO:0003727	87	2	18094	48	RBMS3,MSI2
2.246e-02	-3.80	FGFR1OP2 (FGFR1 oncogene partner 2)	protein interactions	26127	90	2	19454	50	CAMK2G,TNIK
2.246e-02	-3.80	CTDSPL (CTD small phosphatase like)	protein interactions	10217	90	2	19454	50	DTNA,FMN2
2.250e-02	-3.79	response to mechanical stimulus	biological process	GO:0009612	220	3	18204	50	NRXN1,ATP1A2,TNC
2.256e-02	-3.79	EDTRNSPORT	prints domains	PR00173	7	1	5227	17	SLC1A2
2.256e-02	-3.79	HUDSXLRNA	prints domains	PR00961	7	1	5227	17	RBMS3
2.260e-02	-3.79	synovial	COSMIC cancer mutations	synovial	8	1	16828	48	CNTN1
2.260e-02	-3.79	bone-knee-chondrosarcoma-synovial	COSMIC cancer mutations	bone-knee-chondrosarcoma-synovial	8	1	16828	48	CNTN1
2.264e-02	-3.79	LIM_DOMAIN_1	prosite domains	PS00478	71	2	12186	40	ABLIM1,NEBL
2.264e-02	-3.79	LIM_DOMAIN_2	prosite domains	PS50023	71	2	12186	40	ABLIM1,NEBL
2.272e-02	-3.78	human chr3p24.1	chromosome location	human chr3p24.1	12	1	26134	50	RBMS3
2.272e-02	-3.78	human chr6q25.2	chromosome location	human chr6q25.2	12	1	26134	50	SYNE1
2.276e-02	-3.78	NA_DICARBOXYL_SYMP_1	prosite domains	PS00713	7	1	12186	40	SLC1A2
2.276e-02	-3.78	NA_DICARBOXYL_SYMP_2	prosite domains	PS00714	7	1	12186	40	SLC1A2
2.283e-02	-3.78	oligodendrocyte differentiation	biological process	GO:0048709	85	2	18204	50	CNTN1,NTRK2
2.285e-02	-3.78	flotillin complex	cellular component	GO:0016600	9	1	19108	49	SORBS1
2.290e-02	-3.78	Tyw3 (tRNA-yW synthesizing protein 3 homolog (S. cerevisiae))	protein interactions	209584	9	1	19454	50	CTNNA2
2.290e-02	-3.78	CUX2 (cut like homeobox 2)	protein interactions	23316	9	1	19454	50	NAV3
2.290e-02	-3.78	DUX3 (double homeobox 3)	protein interactions	26582	9	1	19454	50	FAT3
2.290e-02	-3.78	MMP19 (matrix metallopeptidase 19)	protein interactions	4327	9	1	19454	50	SYNE1
2.290e-02	-3.78	RBPJL (recombination signal binding protein for immunoglobulin kappa J region like)	protein interactions	11317	9	1	19454	50	FAT3
2.290e-02	-3.78	CAMK2N1 (calcium/calmodulin dependent protein kinase II inhibitor 1)	protein interactions	55450	9	1	19454	50	CAMK2G
2.290e-02	-3.78	NRXN2 (neurexin 2)	protein interactions	9379	9	1	19454	50	MACF1
2.292e-02	-3.78	SOS1 (SOS Ras/Rac guanine nucleotide exchange factor 1)	protein interactions	6654	91	2	19454	50	SORBS1,TNIK
2.299e-02	-3.77	CAMK2A (calcium/calmodulin dependent protein kinase II alpha)	protein interactions	815	237	3	19454	50	CAMK2G,GPM6A,SOX5
2.299e-02	-3.77	CLU (clusterin)	protein interactions	1191	237	3	19454	50	LRP1B,TNIK,TNC
2.320e-02	-3.76	Acrivastine H1-Antihistamine Action	SMPDB pathways	SMP0059881	8	1	1369	4	PLCB1
2.320e-02	-3.76	Chlorcyclizine H1-Antihistamine Action	SMPDB pathways	SMP0058931	8	1	1369	4	PLCB1
2.320e-02	-3.76	Thenyldiamine H1-Antihistamine Action	SMPDB pathways	SMP0062624	8	1	1369	4	PLCB1
2.320e-02	-3.76	Phenyltoloxamine H1-Antihistamine Action	SMPDB pathways	SMP0058916	8	1	1369	4	PLCB1
2.320e-02	-3.76	Bromodiphenhydramine H1-Antihistamine Action	SMPDB pathways	SMP0058813	8	1	1369	4	PLCB1
2.320e-02	-3.76	Flunarizine H1-Antihistamine Action	SMPDB pathways	SMP0061047	8	1	1369	4	PLCB1
2.320e-02	-3.76	Orphenadrine H1-Antihistamine Action	SMPDB pathways	SMP0058808	8	1	1369	4	PLCB1
2.320e-02	-3.76	Terfenadine H1-Antihistamine Action	SMPDB pathways	SMP0060208	8	1	1369	4	PLCB1
2.320e-02	-3.76	Betahistine H1-Antihistamine Action	SMPDB pathways	SMP0060744	8	1	1369	4	PLCB1
2.320e-02	-3.76	Dimetindene H1-Antihistamine Action	SMPDB pathways	SMP0057582	8	1	1369	4	PLCB1
2.320e-02	-3.76	Brompheniramine H1-Antihistamine Action	SMPDB pathways	SMP0057579	8	1	1369	4	PLCB1
2.320e-02	-3.76	Tritoqualine H1-Antihistamine Action	SMPDB pathways	SMP0062895	8	1	1369	4	PLCB1
2.320e-02	-3.76	Clemastine H1-Antihistamine Action	SMPDB pathways	SMP0058891	8	1	1369	4	PLCB1
2.320e-02	-3.76	Olopatadine H1-Antihistamine Action	SMPDB pathways	SMP0060740	8	1	1369	4	PLCB1
2.320e-02	-3.76	Histapyrrodine H1-Antihistamine Action	SMPDB pathways	SMP0058732	8	1	1369	4	PLCB1
2.320e-02	-3.76	Oxomemazine H1-Antihistamine Action	SMPDB pathways	SMP0059738	8	1	1369	4	PLCB1
2.320e-02	-3.76	Intracellular Signalling Through Prostacyclin Receptor and Prostacyclin	SMPDB pathways	SMP0000354	8	1	1369	4	ADCY2
2.320e-02	-3.76	Chloropyramine H1-Antihistamine Action	SMPDB pathways	SMP0057585	8	1	1369	4	PLCB1
2.320e-02	-3.76	Mepyramine H1-Antihistamine Action	SMPDB pathways	SMP0057583	8	1	1369	4	PLCB1
2.320e-02	-3.76	Ebastine H1-Antihistamine Action	SMPDB pathways	SMP0060204	8	1	1369	4	PLCB1
2.320e-02	-3.76	Diphenhydramine H1-Antihistamine Action	SMPDB pathways	SMP0058785	8	1	1369	4	PLCB1
2.320e-02	-3.76	Quetiapine H1-Antihistamine Action	SMPDB pathways	SMP0062884	8	1	1369	4	PLCB1
2.320e-02	-3.76	Thonzylamine H1-Antihistamine Action	SMPDB pathways	SMP0058769	8	1	1369	4	PLCB1
2.320e-02	-3.76	Mizolastine H1-Antihistamine Action	SMPDB pathways	SMP0060230	8	1	1369	4	PLCB1
2.320e-02	-3.76	Temelastine H1-Antihistamine Action	SMPDB pathways	SMP0062880	8	1	1369	4	PLCB1
2.320e-02	-3.76	Triprolidine H1-Antihistamine Action	SMPDB pathways	SMP0057581	8	1	1369	4	PLCB1
2.320e-02	-3.76	Pimethixene H1-Antihistamine Action	SMPDB pathways	SMP0062886	8	1	1369	4	PLCB1
2.320e-02	-3.76	Epinastine H1-Antihistamine Action	SMPDB pathways	SMP0061191	8	1	1369	4	PLCB1
2.320e-02	-3.76	Histamine H1 Receptor Activation	SMPDB pathways	SMP0063452	8	1	1369	4	PLCB1
2.320e-02	-3.76	Chlorphenoxamine H1-Antihistamine Action	SMPDB pathways	SMP0058903	8	1	1369	4	PLCB1
2.320e-02	-3.76	Cetirizine H1-Antihistamine Action	SMPDB pathways	SMP0059058	8	1	1369	4	PLCB1
2.320e-02	-3.76	Doxepin H1-Antihistamine Action	SMPDB pathways	SMP0059872	8	1	1369	4	PLCB1
2.320e-02	-3.76	Tripelennamine H1-Antihistamine Action	SMPDB pathways	SMP0057587	8	1	1369	4	PLCB1
2.320e-02	-3.76	Lysophosphatidic Acid LPA3 Signalling	SMPDB pathways	SMP0063755	8	1	1369	4	PLCB1
2.320e-02	-3.76	Methdilazine H1-Antihistamine Action	SMPDB pathways	SMP0059730	8	1	1369	4	PLCB1
2.320e-02	-3.76	Azatadine H1-Antihistamine Action	SMPDB pathways	SMP0059865	8	1	1369	4	PLCB1
2.320e-02	-3.76	Emedastine H1-Antihistamine Action	SMPDB pathways	SMP0061040	8	1	1369	4	PLCB1
2.320e-02	-3.76	Carbinoxamine H1-Antihistamine Action	SMPDB pathways	SMP0058797	8	1	1369	4	PLCB1
2.320e-02	-3.76	Oxatomide H1-Antihistamine Action	SMPDB pathways	SMP0059044	8	1	1369	4	PLCB1
2.320e-02	-3.76	Phenbenzamine H1-Antihistamine Action	SMPDB pathways	SMP0059702	8	1	1369	4	PLCB1
2.320e-02	-3.76	Loratadine H1-Antihistamine Action	SMPDB pathways	SMP0060195	8	1	1369	4	PLCB1
2.320e-02	-3.76	Chlorphenamine H1-Antihistamine Action	SMPDB pathways	SMP0056661	8	1	1369	4	PLCB1
2.320e-02	-3.76	Deptropine H1-Antihistamine Action	SMPDB pathways	SMP0062883	8	1	1369	4	PLCB1
2.320e-02	-3.76	Mirtazapine H1-Antihistamine Action	SMPDB pathways	SMP0062885	8	1	1369	4	PLCB1
2.320e-02	-3.76	Fexofenadine H1-Antihistamine Action	SMPDB pathways	SMP0060218	8	1	1369	4	PLCB1
2.320e-02	-3.76	Rupatadine H1-Antihistamine Action	SMPDB pathways	SMP0060235	8	1	1369	4	PLCB1
2.320e-02	-3.76	Doxylamine H1-Antihistamine Action	SMPDB pathways	SMP0058803	8	1	1369	4	PLCB1
2.320e-02	-3.76	Hydroxyzine H1-Antihistamine Action	SMPDB pathways	SMP0058936	8	1	1369	4	PLCB1
2.320e-02	-3.76	Homochlorcyclizine H1-Antihistamine Action	SMPDB pathways	SMP0062795	8	1	1369	4	PLCB1
2.320e-02	-3.76	Bamipine H1-Antihistamine Action	SMPDB pathways	SMP0062882	8	1	1369	4	PLCB1
2.320e-02	-3.76	Astemizole H1-Antihistamine Action	SMPDB pathways	SMP0059897	8	1	1369	4	PLCB1
2.320e-02	-3.76	Cyproheptadine H1-Antihistamine Action	SMPDB pathways	SMP0059694	8	1	1369	4	PLCB1
2.320e-02	-3.76	Cinnarizine H1-Antihistamine Action	SMPDB pathways	SMP0059110	8	1	1369	4	PLCB1
2.320e-02	-3.76	Azelastine H1-Antihistamine Action	SMPDB pathways	SMP0060741	8	1	1369	4	PLCB1
2.320e-02	-3.76	Clocinizine H1-Antihistamine Action	SMPDB pathways	SMP0062788	8	1	1369	4	PLCB1
2.320e-02	-3.76	Tolpropamine H1-Antihistamine Action	SMPDB pathways	SMP0062621	8	1	1369	4	PLCB1
2.320e-02	-3.76	Methapyrilene H1-Antihistamine Action	SMPDB pathways	SMP0058741	8	1	1369	4	PLCB1
2.320e-02	-3.76	Levocetirizine H1-Antihistamine Action	SMPDB pathways	SMP0059114	8	1	1369	4	PLCB1
2.320e-02	-3.76	Buclizine H1-Antihistamine Action	SMPDB pathways	SMP0058964	8	1	1369	4	PLCB1
2.320e-02	-3.76	Mequitazine H1-Antihistamine Action	SMPDB pathways	SMP0059720	8	1	1369	4	PLCB1
2.320e-02	-3.76	Meclizine H1-Antihistamine Action	SMPDB pathways	SMP0058956	8	1	1369	4	PLCB1
2.320e-02	-3.76	Talastine H1-Antihistamine Action	SMPDB pathways	SMP0057586	8	1	1369	4	PLCB1
2.320e-02	-3.76	Thenalidine H1-Antihistamine Action	SMPDB pathways	SMP0062894	8	1	1369	4	PLCB1
2.320e-02	-3.76	Phenindamine H1-Antihistamine Action	SMPDB pathways	SMP0061190	8	1	1369	4	PLCB1
2.320e-02	-3.76	Latrepirdine H1-Antihistamine Action	SMPDB pathways	SMP0062623	8	1	1369	4	PLCB1
2.320e-02	-3.76	Isothipendyl H1-Antihistamine Action	SMPDB pathways	SMP0059716	8	1	1369	4	PLCB1
2.320e-02	-3.76	Propiomazine H1-Antihistamine Action	SMPDB pathways	SMP0062625	8	1	1369	4	PLCB1
2.320e-02	-3.76	Pheniramine H1-Antihistamine Action	SMPDB pathways	SMP0056662	8	1	1369	4	PLCB1
2.320e-02	-3.76	Pyrrobutamine H1-Antihistamine Action	SMPDB pathways	SMP0062887	8	1	1369	4	PLCB1
2.320e-02	-3.76	Cyclizine H1-Antihistamine Action	SMPDB pathways	SMP0058923	8	1	1369	4	PLCB1
2.320e-02	-3.76	Quifenadine H1-Antihistamine Action	SMPDB pathways	SMP0060743	8	1	1369	4	PLCB1
2.320e-02	-3.76	Mebhydrolin H1-Antihistamine Action	SMPDB pathways	SMP0061052	8	1	1369	4	PLCB1
2.320e-02	-3.76	Ketotifen H1-Antihistamine Action	SMPDB pathways	SMP0059868	8	1	1369	4	PLCB1
2.320e-02	-3.76	Hydroxyethylpromethazine H1-Antihistamine Action	SMPDB pathways	SMP0059710	8	1	1369	4	PLCB1
2.320e-02	-3.76	Embramine H1-Antihistamine Action	SMPDB pathways	SMP0062622	8	1	1369	4	PLCB1
2.320e-02	-3.76	Antazoline H1-Antihistamine Action	SMPDB pathways	SMP0057584	8	1	1369	4	PLCB1
2.320e-02	-3.76	Thiazinamium H1-Antihistamine Action	SMPDB pathways	SMP0060742	8	1	1369	4	PLCB1
2.320e-02	-3.76	Alimemazine H1-Antihistamine Action	SMPDB pathways	SMP0059689	8	1	1369	4	PLCB1
2.320e-02	-3.76	Levocabastine H1-Antihistamine Action	SMPDB pathways	SMP0060224	8	1	1369	4	PLCB1
2.320e-02	-3.76	Fenethazine H1-Antihistamine Action	SMPDB pathways	SMP0059707	8	1	1369	4	PLCB1
2.320e-02	-3.76	Dexchlorpheniramine H1-Antihistamine Action	SMPDB pathways	SMP0056811	8	1	1369	4	PLCB1
2.320e-02	-3.76	Bilastine H1-Antihistamine Action	SMPDB pathways	SMP0060170	8	1	1369	4	PLCB1
2.320e-02	-3.76	Diphenylpyraline H1-Antihistamine Action	SMPDB pathways	SMP0058908	8	1	1369	4	PLCB1
2.320e-02	-3.76	Bepotastine H1-Antihistamine Action	SMPDB pathways	SMP0060058	8	1	1369	4	PLCB1
2.320e-02	-3.76	Alcaftadine H1-Antihistamine Action	SMPDB pathways	SMP0062881	8	1	1369	4	PLCB1
2.320e-02	-3.76	Dexbrompheniramine H1-Antihistamine Action	SMPDB pathways	SMP0057580	8	1	1369	4	PLCB1
2.320e-02	-3.76	Promethazine H1-Antihistamine Action	SMPDB pathways	SMP0059211	8	1	1369	4	PLCB1
2.320e-02	-3.76	Desloratadine H1-Antihistamine Action	SMPDB pathways	SMP0060201	8	1	1369	4	PLCB1
2.334e-02	-3.76	central nervous system neuron development	biological process	GO:0021954	86	2	18204	50	DCLK2,NTRK2
2.334e-02	-3.76	myofibril	cellular component	GO:0030016	239	3	19108	49	SYNE1,RYR3,NEBL
2.346e-02	-3.75	cellular response to oxygen-containing compound	biological process	GO:1901701	1047	7	18204	50	SORBS1,PLCB1,TNC,RORA,RYR3,SLC1A2,ADCY2
2.352e-02	-3.75	organic anion transport	biological process	GO:0015711	398	4	18204	50	NTRK2,SLC4A4,SLC1A2,SFXN5
2.384e-02	-3.74	DISC1 (DISC1 scaffold protein)	protein interactions	27185	427	4	19454	50	SYNE1,TNIK,MACF1,KALRN
2.387e-02	-3.74	Free fatty acids regulate insulin secretion	REACTOME pathways	R-HSA-400451	8	1	10285	31	PLCB1
2.387e-02	-3.74	Release of Hh-Np from the secreting cell	REACTOME pathways	R-HSA-5362798	8	1	10285	31	GPC5
2.387e-02	-3.74	Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion	REACTOME pathways	R-HSA-434316	8	1	10285	31	PLCB1
2.400e-02	-3.73	spindle	COSMIC cancer mutations	spindle	386	4	16828	48	KALRN,CTNND2,MACF1,TRPM3
2.401e-02	-3.73	ERBIN (erbb2 interacting protein)	protein interactions	55914	241	3	19454	50	NTRK2,CTNND2,PARD3
2.404e-02	-3.73	Peptidase_S9	interpro domains	IPR001375	9	1	18521	50	DPP6
2.404e-02	-3.73	Doublecortin_dom	interpro domains	IPR003533	9	1	18521	50	DCLK2
2.404e-02	-3.73	DNA-bd_RFX	interpro domains	IPR003150	9	1	18521	50	RFX4
2.404e-02	-3.73	Band3_cytoplasmic_dom	interpro domains	IPR013769	9	1	18521	50	SLC4A4
2.407e-02	-3.73	Villin headpiece domain	gene3d domains	1.10.950.10	8	1	14470	44	ABLIM1
2.410e-02	-3.73	regulation of cell growth	biological process	GO:0001558	401	4	18204	50	NRG3,TNC,NRCAM,MACF1
2.420e-02	-3.72	fibula	COSMIC cancer mutations	fibula	387	4	16828	48	TRPM3,MACF1,SYNE1,NRXN1
2.426e-02	-3.72	clear_cell_renal_cell_carcinoma	COSMIC cancer mutations	clear_cell_renal_cell_carcinoma	13924	45	16828	48	NEBL,NRCAM,LSAMP,RORA,MGAT4C,NAV2,GPM6A,ABLIM1,NHSL1,SLC14A1,PITPNC1,PLCB1,TNC,FAT3,NAV3,ADCY2,GPC5,MACF1,DGKG,MSI2,KALRN,SYNE1,CAMK2G,SOX5,TNIK,LRP1B,ATP1A2,NTRK2,TRPM3,PARD3,SLC1A2,SLC4A4,SORBS1,SFXN5,CTNND2,RYR3,NRG3,NKAIN3,FMN2,DTNA,HPSE2,NRXN1,DCLK2,CNTN1,DPP6
2.426e-02	-3.72	kidney-carcinoma-clear_cell_renal_cell_carcinoma	COSMIC cancer mutations	kidney-carcinoma-clear_cell_renal_cell_carcinoma	13924	45	16828	48	NEBL,NRCAM,RORA,LSAMP,MGAT4C,NAV2,GPM6A,ABLIM1,NHSL1,SLC14A1,PITPNC1,PLCB1,TNC,FAT3,NAV3,ADCY2,MACF1,GPC5,DGKG,MSI2,KALRN,SYNE1,CAMK2G,SOX5,TNIK,LRP1B,ATP1A2,NTRK2,TRPM3,PARD3,SLC1A2,SLC4A4,SORBS1,SFXN5,CTNND2,RYR3,NRG3,NKAIN3,DTNA,FMN2,HPSE2,NRXN1,DCLK2,CNTN1,DPP6
2.435e-02	-3.72	WWC1 (WW and C2 domain containing 1)	protein interactions	23286	94	2	19454	50	TNIK,ABLIM1
2.435e-02	-3.72	GRIN1 (glutamate ionotropic receptor NMDA type subunit 1)	protein interactions	2902	94	2	19454	50	NTRK2,CAMK2G
2.439e-02	-3.71	regulation of growth	biological process	GO:0040008	603	5	18204	50	PLCB1,NRG3,TNC,NRCAM,MACF1
2.446e-02	-3.71	hindbrain radial glia guided cell migration	biological process	GO:0021932	9	1	18204	50	CTNNA2
2.446e-02	-3.71	release of sequestered calcium ion into cytosol by sarcoplasmic reticulum	biological process	GO:0014808	9	1	18204	50	RYR3
2.446e-02	-3.71	negative regulation of striated muscle contraction	biological process	GO:0045988	9	1	18204	50	ATP1A2
2.446e-02	-3.71	interleukin-12-mediated signaling pathway	biological process	GO:0035722	9	1	18204	50	PLCB1
2.446e-02	-3.71	negative regulation of actin nucleation	biological process	GO:0051126	9	1	18204	50	CTNNA2
2.446e-02	-3.71	positive regulation of synapse maturation	biological process	GO:0090129	9	1	18204	50	NRXN1
2.446e-02	-3.71	mesenchymal-epithelial cell signaling	biological process	GO:0060638	9	1	18204	50	TNC
2.446e-02	-3.71	negative regulation of cellular extravasation	biological process	GO:0002692	9	1	18204	50	PLCB1
2.450e-02	-3.71	upper_arm	COSMIC cancer mutations	upper_arm	582	5	16828	48	PLCB1,SLC4A4,FMN2,SYNE1,LRP1B
2.452e-02	-3.71	Band_3_cyto	pfam domains	PF07565	9	1	17795	49	SLC4A4
2.452e-02	-3.71	RFX_DNA_binding	pfam domains	PF02257	9	1	17795	49	RFX4
2.452e-02	-3.71	Peptidase_S9	pfam domains	PF00326	9	1	17795	49	DPP6
2.460e-02	-3.70	cellular localization	biological process	GO:0051641	2660	13	18204	50	PARD3,SLC1A2,SYNE1,FMN2,DCLK2,NRCAM,SLC14A1,CAMK2G,DPP6,TNIK,LRP1B,NRXN1,MACF1
2.471e-02	-3.70	macromolecule localization	biological process	GO:0033036	2376	12	18204	50	CAMK2G,NRCAM,DPP6,MACF1,TNIK,LRP1B,NRXN1,PARD3,PITPNC1,SYNE1,FMN2,DCLK2
2.483e-02	-3.70	HER-positive_carcinoma	COSMIC cancer mutations	HER-positive_carcinoma	2025	11	16828	48	NTRK2,MSI2,NRG3,TNC,GPC5,RORA,NRCAM,CNTN1,DPP6,ABLIM1,RBMS3
2.483e-02	-3.70	breast-carcinoma-HER-positive_carcinoma	COSMIC cancer mutations	breast-carcinoma-HER-positive_carcinoma	2025	11	16828	48	NTRK2,MSI2,NRG3,TNC,GPC5,RORA,NRCAM,CNTN1,DPP6,ABLIM1,RBMS3
2.483e-02	-3.70	STRIP1 (striatin interacting protein 1)	protein interactions	85369	95	2	19454	50	CAMK2G,TNIK
2.495e-02	-3.69	PLEC	smart domains	SM00250	7	1	9717	35	MACF1
2.499e-02	-3.69	peritoneum-appendix-other-pseudomyxoma_peritonei	COSMIC cancer mutations	peritoneum-appendix-other-pseudomyxoma_peritonei	585	5	16828	48	TNC,PLCB1,FAT3,MACF1,SYNE1
2.499e-02	-3.69	pseudomyxoma_peritonei	COSMIC cancer mutations	pseudomyxoma_peritonei	585	5	16828	48	FAT3,TNC,PLCB1,MACF1,SYNE1
2.515e-02	-3.68	appendix	COSMIC cancer mutations	appendix	586	5	16828	48	SYNE1,MACF1,TNC,PLCB1,FAT3
2.521e-02	-3.68	sarcoplasm	cellular component	GO:0016528	96	2	19108	49	CAMK2G,RYR3
2.531e-02	-3.68	uveal_tract	COSMIC cancer mutations	uveal_tract	587	5	16828	48	TRPM3,CTNND2,MACF1,KALRN,ADCY2
2.531e-02	-3.68	peritoneum	COSMIC cancer mutations	peritoneum	587	5	16828	48	FAT3,TNC,PLCB1,MACF1,SYNE1
2.541e-02	-3.67	CHRDL1 (chordin like 1)	protein interactions	91851	10	1	19454	50	LRP1B
2.541e-02	-3.67	AXDND1 (axonemal dynein light chain domain containing 1)	protein interactions	126859	10	1	19454	50	SYNE1
2.541e-02	-3.67	Vbp1 (von Hippel-Lindau binding protein 1)	protein interactions	22327	10	1	19454	50	ABLIM1
2.541e-02	-3.67	SLC8A2 (solute carrier family 8 member A2)	protein interactions	6543	10	1	19454	50	GPM6A
2.541e-02	-3.67	IL17RE (interleukin 17 receptor E)	protein interactions	132014	10	1	19454	50	FAT3
2.541e-02	-3.67	GSG1 (germ cell associated 1)	protein interactions	83445	10	1	19454	50	PITPNC1
2.541e-02	-3.67	ZNF563 (zinc finger protein 563)	protein interactions	147837	10	1	19454	50	LRP1B
2.541e-02	-3.67	NAT8L (N-acetyltransferase 8 like)	protein interactions	339983	10	1	19454	50	FAT3
2.541e-02	-3.67	CALB2 (calbindin 2)	protein interactions	794	10	1	19454	50	GPM6A
2.541e-02	-3.67	DOA4 (ubiquitin-specific protease DOA4)	protein interactions	851641	10	1	19454	50	NAV2
2.546e-02	-3.67	regulation of biological process	biological process	GO:0050789	12079	40	18204	50	HPSE2,SLC1A2,MAPK10,ADCY2,CNTN1,FAT3,RYR3,NKAIN3,PLCB1,FMN2,NAV3,SYNE1,RFX4,RBMS3,NRCAM,DTNA,NRXN1,GPC5,DPP6,SFXN5,PITPNC1,CTNNA2,PARD3,SOX5,ATP1A2,NTRK2,CTNND2,DCLK2,SORBS1,GPM6A,CAMK2G,DGKG,NRG3,KALRN,MSI2,TNIK,MACF1,RORA,SLC4A4,TNC
2.551e-02	-3.67	lipid binding	molecular function	GO:0008289	861	6	18094	48	PITPNC1,PARD3,ATP1A2,RORA,DGKG,PLCB1
2.579e-02	-3.66	biological regulation	biological process	GO:0065007	12501	41	18204	50	PLCB1,FMN2,NAV3,SYNE1,RFX4,RBMS3,NKAIN3,RYR3,SLC1A2,HPSE2,MAPK10,ADCY2,CNTN1,FAT3,DPP6,NAV2,NRXN1,GPC5,NRCAM,DTNA,SORBS1,ATP1A2,SOX5,DCLK2,CTNND2,NTRK2,PARD3,SFXN5,PITPNC1,CTNNA2,TNC,TNIK,MACF1,RORA,SLC4A4,NRG3,KALRN,MSI2,GPM6A,CAMK2G,DGKG
2.581e-02	-3.66	BTG3 (BTG anti-proliferation factor 3)	protein interactions	10950	97	2	19454	50	DCLK2,SYNE1
2.581e-02	-3.66	SYNE1 (spectrin repeat containing nuclear envelope protein 1)	protein interactions	23345	97	2	19454	50	SYNE1,TNIK
2.585e-02	-3.66	NCOR2 (nuclear receptor corepressor 2)	protein interactions	9612	248	3	19454	50	DGKG,SOX5,TNIK
2.595e-02	-3.65	contractile muscle fiber	cellular component	GO:0043292	249	3	19108	49	NEBL,SYNE1,RYR3
2.597e-02	-3.65	HP	prosite domains	PS51089	8	1	12186	40	ABLIM1
2.607e-02	-3.65	Excitatory Neural Signalling Through 5-HTR 6 and Serotonin	SMPDB pathways	SMP0000312	9	1	1369	4	ADCY2
2.607e-02	-3.65	Lysophosphatidic Acid LPA1 Signalling	SMPDB pathways	SMP0063746	9	1	1369	4	PLCB1
2.607e-02	-3.65	Excitatory Neural Signalling Through 5-HTR 7 and Serotonin	SMPDB pathways	SMP0000311	9	1	1369	4	ADCY2
2.607e-02	-3.65	Lysophosphatidic Acid LPA2 Signalling	SMPDB pathways	SMP0063753	9	1	1369	4	PLCB1
2.607e-02	-3.65	Excitatory Neural Signalling Through 5-HTR 4 and Serotonin	SMPDB pathways	SMP0000309	9	1	1369	4	ADCY2
2.607e-02	-3.65	Intracellular Signalling Through FSH Receptor and Follicle Stimulating Hormone	SMPDB pathways	SMP0000333	9	1	1369	4	ADCY2
2.607e-02	-3.65	Intracellular Signalling Through Histamine H2 Receptor and Histamine	SMPDB pathways	SMP0000335	9	1	1369	4	ADCY2
2.612e-02	-3.65	GAN (gigaxonin)	protein interactions	8139	249	3	19454	50	SYNE1,CTNNA2,PLCB1
2.622e-02	-3.64	neurotrophin binding	molecular function	GO:0043121	10	1	18094	48	NTRK2
2.622e-02	-3.64	phosphatidylinositol transfer activity	molecular function	GO:0008526	10	1	18094	48	PITPNC1
2.625e-02	-3.64	cell surface	cellular component	GO:0009986	896	6	19108	49	SLC1A2,NRXN1,GPC5,SLC4A4,NRCAM,ATP1A2
2.631e-02	-3.64	FRAS1 (Fraser extracellular matrix complex subunit 1)	protein interactions	80144	98	2	19454	50	MGAT4C,HPSE2
2.645e-02	-3.63	protein tetramerization	biological process	GO:0051262	92	2	18204	50	RYR3,TRPM3
2.646e-02	-3.63	human chr2p13.2	chromosome location	human chr2p13.2	14	1	26134	50	SFXN5
2.646e-02	-3.63	human chr2p16.3	chromosome location	human chr2p16.3	14	1	26134	50	NRXN1
2.646e-02	-3.63	human chr9q33.1	chromosome location	human chr9q33.1	14	1	26134	50	TNC
2.648e-02	-3.63	ankle	COSMIC cancer mutations	ankle	398	4	16828	48	PLCB1,NRG3,PARD3,KALRN
2.667e-02	-3.62	Endothelins	Pathway Interaction DB	endothelinpathway	53	2	2226	11	ADCY2,PLCB1
2.668e-02	-3.62	HCO3_transpt-like_TM_dom	interpro domains	IPR011531	10	1	18521	50	SLC4A4
2.668e-02	-3.62	Diacylglycerol_kin_accessory	interpro domains	IPR000756	10	1	18521	50	DGKG
2.668e-02	-3.62	MIR_motif	interpro domains	IPR016093	10	1	18521	50	RYR3
2.668e-02	-3.62	MIR_dom_sf	interpro domains	IPR036300	10	1	18521	50	RYR3
2.668e-02	-3.62	HCO3_transpt_euk	interpro domains	IPR003020	10	1	18521	50	SLC4A4
2.668e-02	-3.62	DGK	interpro domains	IPR037607	10	1	18521	50	DGKG
2.668e-02	-3.62	PTrfase/Anion_transptr	interpro domains	IPR016152	10	1	18521	50	SLC4A4
2.668e-02	-3.62	Doublecortin_dom_sf	interpro domains	IPR036572	10	1	18521	50	DCLK2
2.678e-02	-3.62	YWHAE (tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein epsilon)	protein interactions	7531	1150	7	19454	50	SORBS1,PARD3,ABLIM1,CAMK2G,NAV2,DCLK2,MACF1
2.682e-02	-3.62	LIM	smart domains	SM00132	71	2	9717	35	ABLIM1,NEBL
2.685e-02	-3.62	KRAS (KRAS proto-oncogene, GTPase)	protein interactions	3845	2876	13	19454	50	MACF1,PLCB1,TNIK,RFX4,FMN2,CAMK2G,NAV2,DTNA,ABLIM1,DCLK2,SLC4A4,NAV3,PARD3
2.688e-02	-3.62	Opioid Signalling	REACTOME pathways	R-HSA-111885	85	2	10285	31	PLCB1,ADCY2
2.699e-02	-3.61	regulation of extent of cell growth	biological process	GO:0061387	93	2	18204	50	MACF1,NRCAM
2.701e-02	-3.61	anchoring junction	cellular component	GO:0070161	902	6	19108	49	SORBS1,ATP1A2,CTNND2,TNC,PARD3,CTNNA2
2.704e-02	-3.61	Doublecortin domain	gene3d domains	3.10.20.230	9	1	14470	44	DCLK2
2.712e-02	-3.61	craniopharyngioma	COSMIC cancer mutations	craniopharyngioma	401	4	16828	48	RYR3,NRCAM,PARD3,SYNE1
2.712e-02	-3.61	craniopharyngeal_duct	COSMIC cancer mutations	craniopharyngeal_duct	401	4	16828	48	NRCAM,PARD3,SYNE1,RYR3
2.714e-02	-3.61	establishment of centrosome localization	biological process	GO:0051660	10	1	18204	50	PARD3
2.714e-02	-3.61	substrate-independent telencephalic tangential interneuron migration	biological process	GO:0021843	10	1	18204	50	NRG3
2.714e-02	-3.61	urea transmembrane transport	biological process	GO:0071918	10	1	18204	50	SLC14A1
2.714e-02	-3.61	release of sequestered calcium ion into cytosol by endoplasmic reticulum	biological process	GO:1903514	10	1	18204	50	RYR3
2.714e-02	-3.61	postsynaptic membrane assembly	biological process	GO:0097104	10	1	18204	50	NRXN1
2.714e-02	-3.61	regulation of mesenchymal stem cell differentiation	biological process	GO:2000739	10	1	18204	50	SOX5
2.714e-02	-3.61	trans-synaptic signaling, modulating synaptic transmission	biological process	GO:0099550	10	1	18204	50	NTRK2
2.714e-02	-3.61	cAMP biosynthetic process	biological process	GO:0006171	10	1	18204	50	ADCY2
2.714e-02	-3.61	retinal rod cell development	biological process	GO:0046548	10	1	18204	50	NTRK2
2.714e-02	-3.61	substrate-independent telencephalic tangential migration	biological process	GO:0021826	10	1	18204	50	NRG3
2.714e-02	-3.61	cellular response to cocaine	biological process	GO:0071314	10	1	18204	50	SLC1A2
2.714e-02	-3.61	learned vocalization behavior or vocal learning	biological process	GO:0098598	10	1	18204	50	NRXN1
2.714e-02	-3.61	postsynaptic density assembly	biological process	GO:0097107	10	1	18204	50	NRXN1
2.714e-02	-3.61	cellular response to brain-derived neurotrophic factor stimulus	biological process	GO:1990416	10	1	18204	50	NTRK2
2.719e-02	-3.61	extrinsic component of plasma membrane	cellular component	GO:0019897	100	2	19108	49	CTNNA2,DTNA
2.720e-02	-3.60	HCO3_cotransp	pfam domains	PF00955	10	1	17795	49	SLC4A4
2.720e-02	-3.60	DAGK_acc	pfam domains	PF00609	10	1	17795	49	DGKG
2.720e-02	-3.60	MIR	pfam domains	PF02815	10	1	17795	49	RYR3
2.731e-02	-3.60	APBA1 (amyloid beta precursor protein binding family A member 1)	protein interactions	320	100	2	19454	50	ABLIM1,NRXN1
2.731e-02	-3.60	ATP4A (ATPase H+/K+ transporting subunit alpha)	protein interactions	495	100	2	19454	50	GPM6A,ATP1A2
2.756e-02	-3.59	muscle contraction	biological process	GO:0006936	238	3	18204	50	DTNA,ATP1A2,RYR3
2.756e-02	-3.59	protein localization to cell periphery	biological process	GO:1990778	238	3	18204	50	DPP6,MACF1,TNIK
2.772e-02	-3.59	EGF_Ca-bd_CS	interpro domains	IPR018097	96	2	18521	50	LRP1B,FAT3
2.777e-02	-3.58	adrenal_gland-adrenal_gland-adrenal_cortical_adenoma-aldosterone_producing	COSMIC cancer mutations	adrenal_gland-adrenal_gland-adrenal_cortical_adenoma-aldosterone_producing	91	2	16828	48	LRP1B,ADCY2
2.783e-02	-3.58	NGF signalling via TRKA from the plasma membrane	REACTOME pathways	R-HSA-187037	387	4	10285	31	ADCY2,NRG3,NTRK2,CAMK2G
2.786e-02	-3.58	microtubule organizing center attachment site	cellular component	GO:0034992	11	1	19108	49	SYNE1
2.786e-02	-3.58	meiotic nuclear membrane microtubule tethering complex	cellular component	GO:0034993	11	1	19108	49	SYNE1
2.786e-02	-3.58	nuclear membrane protein complex	cellular component	GO:0106083	11	1	19108	49	SYNE1
2.786e-02	-3.58	perisynaptic extracellular matrix	cellular component	GO:0098966	11	1	19108	49	TNC
2.786e-02	-3.58	nuclear membrane microtubule tethering complex	cellular component	GO:0106094	11	1	19108	49	SYNE1
2.792e-02	-3.58	SYTL1 (synaptotagmin like 1)	protein interactions	84958	11	1	19454	50	NRXN1
2.792e-02	-3.58	Batf3 (basic leucine zipper transcription factor, ATF-like 3)	protein interactions	381319	11	1	19454	50	MACF1
2.792e-02	-3.58	AQP5 (aquaporin 5)	protein interactions	362	11	1	19454	50	ATP1A2
2.792e-02	-3.58	ADCY5 (adenylate cyclase 5)	protein interactions	111	11	1	19454	50	ADCY2
2.792e-02	-3.58	SCN3A (sodium voltage-gated channel alpha subunit 3)	protein interactions	6328	11	1	19454	50	CNTN1
2.792e-02	-3.58	Gtf2e2 (general transcription factor II E, polypeptide 2 (beta subunit))	protein interactions	68153	11	1	19454	50	NHSL1
2.792e-02	-3.58	SYN3 (synapsin III)	protein interactions	8224	11	1	19454	50	GPM6A
2.792e-02	-3.58	Cobll1 (Cobl-like 1)	protein interactions	319876	11	1	19454	50	ABLIM1
2.792e-02	-3.58	Wipi2 (WD repeat domain, phosphoinositide interacting 2)	protein interactions	74781	11	1	19454	50	MACF1
2.807e-02	-3.57	cardiac muscle cell differentiation	biological process	GO:0055007	95	2	18204	50	NEBL,SYNE1
2.807e-02	-3.57	calcium ion transmembrane import into cytosol	biological process	GO:0097553	95	2	18204	50	RYR3,PLCB1
2.809e-02	-3.57	enzyme-linked receptor protein signaling pathway	biological process	GO:0007167	626	5	18204	50	SORBS1,KALRN,PLCB1,NRG3,NTRK2
2.832e-02	-3.56	human chr12q21.2	chromosome location	human chr12q21.2	15	1	26134	50	NAV3
2.832e-02	-3.56	human chr10p12.31	chromosome location	human chr10p12.31	15	1	26134	50	NEBL
2.832e-02	-3.56	human chr18q12.3	chromosome location	human chr18q12.3	15	1	26134	50	SLC14A1
2.832e-02	-3.56	human chr8q12.3	chromosome location	human chr8q12.3	15	1	26134	50	NKAIN3
2.838e-02	-3.56	response to radiation	biological process	GO:0009314	422	4	18204	50	SLC1A2,MAPK10,ATP1A2,SYNE1
2.846e-02	-3.56	VHP	smart domains	SM00153	8	1	9717	35	ABLIM1
2.853e-02	-3.56	eye	COSMIC cancer mutations	eye	606	5	16828	48	ADCY2,KALRN,MACF1,CTNND2,TRPM3
2.880e-02	-3.55	acetylcholine receptor binding	molecular function	GO:0033130	11	1	18094	48	NRXN1
2.880e-02	-3.55	ATP-dependent diacylglycerol kinase activity	molecular function	GO:0004143	11	1	18094	48	DGKG
2.880e-02	-3.55	sulfur amino acid transmembrane transporter activity	molecular function	GO:0000099	11	1	18094	48	SLC1A2
2.884e-02	-3.55	CSGALNACT2 (chondroitin sulfate N-acetylgalactosaminyltransferase 2)	protein interactions	55454	103	2	19454	50	DPP6,MGAT4C
2.884e-02	-3.55	ZDHHC5 (zinc finger DHHC-type palmitoyltransferase 5)	protein interactions	25921	103	2	19454	50	NTRK2,PARD3
2.891e-02	-3.54	aldosterone_producing	COSMIC cancer mutations	aldosterone_producing	93	2	16828	48	LRP1B,ADCY2
2.892e-02	-3.54	NAKATPASE	prints domains	PR00121	9	1	5227	17	ATP1A2
2.893e-02	-3.54	Intracellular Signalling Through LHCGR Receptor and Luteinizing Hormone/Choriogonadotropin	SMPDB pathways	SMP0000338	10	1	1369	4	ADCY2
2.893e-02	-3.54	Lysophosphatidic Acid LPA5 Signalling	SMPDB pathways	SMP0063757	10	1	1369	4	PLCB1
2.893e-02	-3.54	Lysophosphatidic Acid LPA4 Signalling	SMPDB pathways	SMP0063756	10	1	1369	4	PLCB1
2.903e-02	-3.54	SH3DOMAIN	prints domains	PR00452	83	2	5227	17	SORBS1,NEBL
2.917e-02	-3.53	RFX_DBD	prosite domains	PS51526	9	1	12186	40	RFX4
2.917e-02	-3.53	DC	prosite domains	PS50309	9	1	12186	40	DCLK2
2.917e-02	-3.53	positive regulation of JNK cascade	biological process	GO:0046330	97	2	18204	50	PLCB1,TNIK
2.929e-02	-3.53	EF-hand_7	pfam domains	PF13499	97	2	17795	49	DGKG,MACF1
2.931e-02	-3.53	Tyr_kinase_rcpt_2_CS	interpro domains	IPR002011	11	1	18521	50	NTRK2
2.935e-02	-3.53	tat (Tat)	protein interactions	155871	1718	9	19454	50	RYR3,SORBS1,SLC1A2,ADCY2,CAMK2G,TNC,PLCB1,SLC14A1,NRCAM
2.936e-02	-3.53	HUNK (hormonally up-regulated Neu-associated kinase)	protein interactions	30811	104	2	19454	50	SORBS1,ABLIM1
2.975e-02	-3.51	Adenylate cyclase activating pathway	REACTOME pathways	R-HSA-170660	10	1	10285	31	ADCY2
2.975e-02	-3.51	Acetylcholine regulates insulin secretion	REACTOME pathways	R-HSA-399997	10	1	10285	31	PLCB1
2.975e-02	-3.51	Activation of the AP-1 family of transcription factors	REACTOME pathways	R-HSA-450341	10	1	10285	31	MAPK10
2.975e-02	-3.51	Bicarbonate transporters	REACTOME pathways	R-HSA-425381	10	1	10285	31	SLC4A4
2.975e-02	-3.51	PI3K events in ERBB4 signaling	REACTOME pathways	R-HSA-1250342	10	1	10285	31	NRG3
2.978e-02	-3.51	Heparan sulfate degradation	KEGG pathways	M00078	9	1	7161	24	HPSE2
2.978e-02	-3.51	Heparan sulfate degradation	KEGG pathways	hsa_M00078	9	1	7161	24	HPSE2
2.980e-02	-3.51	organic substance transport	biological process	GO:0071702	1881	10	18204	50	FMN2,LRP1B,SLC4A4,NTRK2,MACF1,SFXN5,SLC1A2,SLC14A1,PITPNC1,CAMK2G
2.981e-02	-3.51	lactone metabolic process	biological process	GO:1901334	11	1	18204	50	ATP1A2
2.981e-02	-3.51	negative regulation of neuron migration	biological process	GO:2001223	11	1	18204	50	NRG3
2.981e-02	-3.51	L-aspartate transmembrane transport	biological process	GO:0070778	11	1	18204	50	SLC1A2
2.981e-02	-3.51	cellular response to caffeine	biological process	GO:0071313	11	1	18204	50	RYR3
2.981e-02	-3.51	cellular response to interleukin-15	biological process	GO:0071350	11	1	18204	50	PLCB1
2.981e-02	-3.51	L-ascorbic acid metabolic process	biological process	GO:0019852	11	1	18204	50	ATP1A2
2.981e-02	-3.51	cellular response to interleukin-12	biological process	GO:0071349	11	1	18204	50	PLCB1
2.981e-02	-3.51	interleukin-15-mediated signaling pathway	biological process	GO:0035723	11	1	18204	50	PLCB1
2.981e-02	-3.51	pyramidal neuron development	biological process	GO:0021860	11	1	18204	50	DCLK2
2.981e-02	-3.51	lipid phosphorylation	biological process	GO:0046834	11	1	18204	50	DGKG
2.981e-02	-3.51	positive regulation of acrosome reaction	biological process	GO:2000344	11	1	18204	50	PLCB1
2.981e-02	-3.51	negative regulation of mesenchymal cell apoptotic process	biological process	GO:2001054	11	1	18204	50	SYNE1
2.981e-02	-3.51	negative regulation of excitatory postsynaptic potential	biological process	GO:0090394	11	1	18204	50	SYNE1
2.981e-02	-3.51	establishment or maintenance of transmembrane electrochemical gradient	biological process	GO:0010248	11	1	18204	50	ATP1A2
2.981e-02	-3.51	glutamate secretion	biological process	GO:0014047	11	1	18204	50	NTRK2
2.981e-02	-3.51	L-glutamate import across plasma membrane	biological process	GO:0098712	11	1	18204	50	SLC1A2
2.981e-02	-3.51	ectodermal placode formation	biological process	GO:0060788	11	1	18204	50	NRG3
2.981e-02	-3.51	ectodermal placode morphogenesis	biological process	GO:0071697	11	1	18204	50	NRG3
2.981e-02	-3.51	egg activation	biological process	GO:0007343	11	1	18204	50	PLCB1
3.000e-02	-3.51	Helical hairpin bin	gene3d domains	1.10.287.570	10	1	14470	44	SLC4A4
3.007e-02	-3.50	haemangiopericytic	COSMIC cancer mutations	haemangiopericytic	95	2	16828	48	RYR3,SYNE1
3.007e-02	-3.50	meninges-meningioma-haemangiopericytic	COSMIC cancer mutations	meninges-meningioma-haemangiopericytic	95	2	16828	48	SYNE1,RYR3
3.034e-02	-3.50	response to wounding	biological process	GO:0009611	431	4	18204	50	SLC1A2,DGKG,MACF1,TNC
3.034e-02	-3.50	trans-synaptic signaling	biological process	GO:0099537	431	4	18204	50	NTRK2,DTNA,NRXN1,SLC1A2
3.035e-02	-3.49	synapse-associated extracellular matrix	cellular component	GO:0099535	12	1	19108	49	TNC
3.035e-02	-3.49	sodium:potassium-exchanging ATPase complex	cellular component	GO:0005890	12	1	19108	49	ATP1A2
3.036e-02	-3.49	NRAS (NRAS proto-oncogene, GTPase)	protein interactions	4893	683	5	19454	50	FMN2,NAV2,PLCB1,MACF1,TNIK
3.040e-02	-3.49	USP6NL (USP6 N-terminal like)	protein interactions	9712	106	2	19454	50	PARD3,NTRK2
3.042e-02	-3.49	ART4 (ADP-ribosyltransferase 4 (inactive) (Dombrock blood group))	protein interactions	420	12	1	19454	50	GPM6A
3.042e-02	-3.49	C2CD4A (C2 calcium dependent domain containing 4A)	protein interactions	145741	12	1	19454	50	FAT3
3.042e-02	-3.49	TCF15 (transcription factor 15)	protein interactions	6939	12	1	19454	50	FAT3
3.042e-02	-3.49	CA4 (carbonic anhydrase 4)	protein interactions	762	12	1	19454	50	SLC4A4
3.042e-02	-3.49	LMP-1 (latent membrane protein LMP-1)	protein interactions	3783750	12	1	19454	50	TNIK
3.042e-02	-3.49	Pard6b (par-6 family cell polarity regulator beta)	protein interactions	58220	12	1	19454	50	PARD3
3.042e-02	-3.49	PROK2 (prokineticin 2)	protein interactions	60675	12	1	19454	50	LRP1B
3.042e-02	-3.49	KIF26A (kinesin family member 26A)	protein interactions	26153	12	1	19454	50	MAPK10
3.042e-02	-3.49	NTF4 (neurotrophin 4)	protein interactions	4909	12	1	19454	50	NTRK2
3.058e-02	-3.49	CTNNB1 (catenin beta 1)	protein interactions	1499	926	6	19454	50	PARD3,CTNND2,SORBS1,CTNNA2,NHSL1,DTNA
3.074e-02	-3.48	regulation of transport	biological process	GO:0051049	1621	9	18204	50	CAMK2G,CNTN1,SLC1A2,NKAIN3,ATP1A2,SORBS1,SYNE1,PLCB1,DPP6
3.085e-02	-3.48	response to alkaloid	biological process	GO:0043279	100	2	18204	50	SLC1A2,RYR3
3.093e-02	-3.48	APOL2 (apolipoprotein L2)	protein interactions	23780	107	2	19454	50	SFXN5,DPP6
3.107e-02	-3.47	MCAM (melanoma cell adhesion molecule)	protein interactions	4162	464	4	19454	50	TNIK,CTNNA2,PLCB1,CNTN1
3.111e-02	-3.47	Post-translational modification: synthesis of GPI-anchored proteins	REACTOME pathways	R-HSA-163125	92	2	10285	31	LSAMP,NTM
3.138e-02	-3.46	adenylate cyclase binding	molecular function	GO:0008179	12	1	18094	48	ADCY2
3.138e-02	-3.46	dipeptidyl-peptidase activity	molecular function	GO:0008239	12	1	18094	48	DPP6
3.138e-02	-3.46	protein binding involved in heterotypic cell-cell adhesion	molecular function	GO:0086080	12	1	18094	48	NRCAM
3.141e-02	-3.46	pituitary	COSMIC cancer mutations	pituitary	420	4	16828	48	RYR3,PARD3,SYNE1,NRCAM
3.142e-02	-3.46	regulation of glucose metabolic process	biological process	GO:0010906	101	2	18204	50	RORA,SORBS1
3.147e-02	-3.46	CLASP1 (cytoplasmic linker associated protein 1)	protein interactions	23332	108	2	19454	50	DCLK2,MACF1
3.147e-02	-3.46	FKBP1A (FKBP prolyl isomerase 1A)	protein interactions	2280	108	2	19454	50	MSI2,RYR3
3.151e-02	-3.46	VCL (vinculin)	protein interactions	7414	268	3	19454	50	NEBL,SORBS1,MACF1
3.179e-02	-3.45	NAD+ Signalling and Aging	SMPDB pathways	SMP0084271	11	1	1369	4	RORA
3.193e-02	-3.44	MAP_kinase_CS	interpro domains	IPR003527	12	1	18521	50	MAPK10
3.193e-02	-3.44	PLC_EF-hand-like	interpro domains	IPR015359	12	1	18521	50	PLCB1
3.197e-02	-3.44	DCX	smart domains	SM00537	9	1	9717	35	DCLK2
3.197e-02	-3.44	Rap1 signaling pathway	KEGG pathways	ko04015	210	3	7161	24	PLCB1,ADCY2,PARD3
3.197e-02	-3.44	Rap1 signaling pathway	KEGG pathways	hsa04015	210	3	7161	24	ADCY2,PARD3,PLCB1
3.199e-02	-3.44	heterocyclic compound binding	molecular function	GO:1901363	2263	11	18094	48	NAV3,MAPK10,DCLK2,KALRN,NAV2,ADCY2,NTRK2,DGKG,TNIK,CAMK2G,ATP1A2
3.200e-02	-3.44	PRR20A (proline rich 20A)	protein interactions	122183	109	2	19454	50	TRPM3,SOX5
3.204e-02	-3.44	human chr9q21.33	chromosome location	human chr9q21.33	17	1	26134	50	NTRK2
3.208e-02	-3.44	HCO3TRNSPORT	prints domains	PR01231	10	1	5227	17	SLC4A4
3.236e-02	-3.43	MIR	prosite domains	PS50919	10	1	12186	40	RYR3
3.246e-02	-3.43	urinary_tract-bladder-carcinoma	COSMIC cancer mutations	urinary_tract-bladder-carcinoma	14050	45	16828	48	SFXN5,CTNND2,SORBS1,SLC1A2,SLC4A4,PARD3,TRPM3,ATP1A2,NTRK2,DPP6,CNTN1,NRXN1,DCLK2,HPSE2,DTNA,FMN2,NTM,NRG3,RYR3,PITPNC1,SLC14A1,ABLIM1,GPM6A,NAV2,MGAT4C,LSAMP,RORA,NRCAM,NEBL,LRP1B,TNIK,SOX5,CAMK2G,RFX4,KALRN,SYNE1,MSI2,DGKG,ADCY2,MACF1,GPC5,NAV3,FAT3,PLCB1,TNC
3.248e-02	-3.43	auditory behavior	biological process	GO:0031223	12	1	18204	50	NRXN1
3.248e-02	-3.43	sulfur amino acid transport	biological process	GO:0000101	12	1	18204	50	SLC1A2
3.248e-02	-3.43	neuronal ion channel clustering	biological process	GO:0045161	12	1	18204	50	NRCAM
3.248e-02	-3.43	response to interleukin-15	biological process	GO:0070672	12	1	18204	50	PLCB1
3.248e-02	-3.43	urea transport	biological process	GO:0015840	12	1	18204	50	SLC14A1
3.248e-02	-3.43	response to interleukin-12	biological process	GO:0070671	12	1	18204	50	PLCB1
3.256e-02	-3.42	EF-hand_like	pfam domains	PF09279	12	1	17795	49	PLCB1
3.257e-02	-3.42	cerebellum development	biological process	GO:0021549	103	2	18204	50	RORA,CNTN1
3.270e-02	-3.42	nervous system process	biological process	GO:0050877	1376	8	18204	50	NTRK2,NRXN1,NAV2,ATP1A2,PLCB1,CTNNA2,ABLIM1,NRCAM
3.276e-02	-3.42	steroid binding	molecular function	GO:0005496	107	2	18094	48	ATP1A2,RORA
3.284e-02	-3.42	postsynaptic cytosol	cellular component	GO:0099524	13	1	19108	49	PLCB1
3.291e-02	-3.41	NPR2 (natriuretic peptide receptor 2)	protein interactions	4882	13	1	19454	50	CAMK2G
3.291e-02	-3.41	NCAN (neurocan)	protein interactions	1463	13	1	19454	50	TNC
3.291e-02	-3.41	TBCC (tubulin folding cofactor C)	protein interactions	6903	13	1	19454	50	NTM
3.291e-02	-3.41	PCAT1 (prostate cancer associated transcript 1)	protein interactions	100750225	13	1	19454	50	NAV3
3.291e-02	-3.41	MYO16 (myosin XVI)	protein interactions	23026	13	1	19454	50	NRXN1
3.291e-02	-3.41	JAM2 (junctional adhesion molecule 2)	protein interactions	58494	13	1	19454	50	PARD3
3.291e-02	-3.41	RNASE4 (ribonuclease A family member 4)	protein interactions	6038	13	1	19454	50	LRP1B
3.291e-02	-3.41	RAB3C (RAB3C, member RAS oncogene family)	protein interactions	115827	13	1	19454	50	GPM6A
3.316e-02	-3.41	EF_HAND_2	prosite domains	PS50222	215	3	12186	40	DGKG,MACF1,RYR3
3.318e-02	-3.41	protein complex oligomerization	biological process	GO:0051259	256	3	18204	50	RYR3,TRPM3,SLC1A2
3.332e-02	-3.40	phosphatidylinositol bisphosphate binding	molecular function	GO:1902936	108	2	18094	48	PARD3,PLCB1
3.363e-02	-3.39	ING5 (inhibitor of growth family member 5)	protein interactions	84289	112	2	19454	50	NAV3,NAV2
3.373e-02	-3.39	gland morphogenesis	biological process	GO:0022612	105	2	18204	50	TNC,NRG3
3.373e-02	-3.39	response to interleukin-1	biological process	GO:0070555	105	2	18204	50	PLCB1,RORA
3.373e-02	-3.39	neural precursor cell proliferation	biological process	GO:0061351	105	2	18204	50	RORA,SOX5
3.373e-02	-3.39	cellular response to alcohol	biological process	GO:0097306	105	2	18204	50	ADCY2,TNC
3.383e-02	-3.39	kidney-carcinoma-chromophobe_renal_cell_carcinoma	COSMIC cancer mutations	kidney-carcinoma-chromophobe_renal_cell_carcinoma	430	4	16828	48	NTRK2,TNIK,DCLK2,CAMK2G
3.383e-02	-3.39	chromophobe_renal_cell_carcinoma	COSMIC cancer mutations	chromophobe_renal_cell_carcinoma	430	4	16828	48	DCLK2,CAMK2G,NTRK2,TNIK
3.395e-02	-3.38	potassium ion binding	molecular function	GO:0030955	13	1	18094	48	ATP1A2
3.395e-02	-3.38	monoatomic cation:bicarbonate symporter activity	molecular function	GO:0140410	13	1	18094	48	SLC4A4
3.408e-02	-3.38	organic anion transmembrane transporter activity	molecular function	GO:0008514	268	3	18094	48	SFXN5,SLC1A2,SLC4A4
3.418e-02	-3.38	GFI1B (growth factor independent 1B transcriptional repressor)	protein interactions	8328	113	2	19454	50	KALRN,DTNA
3.432e-02	-3.37	cellular response to ketone	biological process	GO:1901655	106	2	18204	50	TNC,ADCY2
3.432e-02	-3.37	small_intestine	COSMIC cancer mutations	small_intestine	250	3	16828	48	MACF1,MGAT4C,TNIK
3.457e-02	-3.36	TJP2 (tight junction protein 2)	protein interactions	9414	278	3	19454	50	NEBL,PARD3,SORBS1
3.459e-02	-3.36	plasma membrane raft	cellular component	GO:0044853	114	2	19108	49	SORBS1,ATP1A2
3.459e-02	-3.36	Gap junction	KEGG pathways	ko04540	88	2	7161	24	PLCB1,ADCY2
3.459e-02	-3.36	Gap junction	KEGG pathways	hsa04540	88	2	7161	24	PLCB1,ADCY2
3.464e-02	-3.36	Lactose Degradation	SMPDB pathways	SMP0000457	12	1	1369	4	ATP1A2
3.464e-02	-3.36	Lactose Intolerance	SMPDB pathways	SMP0000458	12	1	1369	4	ATP1A2
3.497e-02	-3.35	postsynaptic membrane	cellular component	GO:0045211	280	3	19108	49	SYNE1,CNTN1,NRCAM
3.500e-02	-3.35	Ion_trans_dom	interpro domains	IPR005821	109	2	18521	50	RYR3,TRPM3
3.514e-02	-3.35	regulation of respiratory gaseous exchange by nervous system process	biological process	GO:0002087	13	1	18204	50	ATP1A2
3.514e-02	-3.35	nervous system process involved in regulation of systemic arterial blood pressure	biological process	GO:0001976	13	1	18204	50	NAV2
3.514e-02	-3.35	postsynaptic specialization assembly	biological process	GO:0098698	13	1	18204	50	NRXN1
3.514e-02	-3.35	ectodermal placode development	biological process	GO:0071696	13	1	18204	50	NRG3
3.514e-02	-3.35	T-helper 17 cell differentiation	biological process	GO:0072539	13	1	18204	50	RORA
3.514e-02	-3.35	cerebellar Purkinje cell differentiation	biological process	GO:0021702	13	1	18204	50	RORA
3.514e-02	-3.35	prepulse inhibition	biological process	GO:0060134	13	1	18204	50	CTNNA2
3.514e-02	-3.35	cellular response to vitamin D	biological process	GO:0071305	13	1	18204	50	TNC
3.514e-02	-3.35	negative regulation of cytosolic calcium ion concentration	biological process	GO:0051481	13	1	18204	50	ATP1A2
3.514e-02	-3.35	defense response to tumor cell	biological process	GO:0002357	13	1	18204	50	RBMS3
3.522e-02	-3.35	Ldl_recept_b	pfam domains	PF00058	13	1	17795	49	LRP1B
3.530e-02	-3.34	CDH2 (cadherin 2)	protein interactions	1000	115	2	19454	50	PARD3,CTNND2
3.530e-02	-3.34	SMAD7 (SMAD family member 7)	protein interactions	4092	115	2	19454	50	PARD3,SOX5
3.530e-02	-3.34	DTNA (dystrobrevin alpha)	protein interactions	1837	115	2	19454	50	PARD3,NTRK2
3.539e-02	-3.34	HRAS (HRas proto-oncogene, GTPase)	protein interactions	3265	712	5	19454	50	TNIK,NAV2,PLCB1,MAPK10,PARD3
3.540e-02	-3.34	CHAT (choline O-acetyltransferase)	protein interactions	1103	14	1	19454	50	CAMK2G
3.540e-02	-3.34	CFAP58 (cilia and flagella associated protein 58)	protein interactions	159686	14	1	19454	50	NAV2
3.540e-02	-3.34	BOD1L2 (biorientation of chromosomes in cell division 1 like 2)	protein interactions	284257	14	1	19454	50	FMN2
3.540e-02	-3.34	RSPO1 (R-spondin 1)	protein interactions	284654	14	1	19454	50	LRP1B
3.540e-02	-3.34	DACT2 (dishevelled binding antagonist of beta catenin 2)	protein interactions	168002	14	1	19454	50	CAMK2G
3.540e-02	-3.34	PLXNA4 (plexin A4)	protein interactions	91584	14	1	19454	50	GPM6A
3.540e-02	-3.34	SLC1A2 (solute carrier family 1 member 2)	protein interactions	6506	14	1	19454	50	SLC1A2
3.540e-02	-3.34	TPSAB1 (tryptase alpha/beta 1)	protein interactions	7177	14	1	19454	50	CAMK2G
3.540e-02	-3.34	FAM218A (family with sequence similarity 218 member A)	protein interactions	152756	14	1	19454	50	FAT3
3.540e-02	-3.34	SYT5 (synaptotagmin 5)	protein interactions	6861	14	1	19454	50	NRXN1
3.540e-02	-3.34	Asap1 (ArfGAP with SH3 domain, ankyrin repeat and PH domain1)	protein interactions	13196	14	1	19454	50	MACF1
3.540e-02	-3.34	RPS14P3 (ribosomal protein S14 pseudogene 3)	protein interactions	644068	14	1	19454	50	FAT3
3.546e-02	-3.34	MIR	smart domains	SM00472	10	1	9717	35	RYR3
3.546e-02	-3.34	DAGKa	smart domains	SM00045	10	1	9717	35	DGKG
3.553e-02	-3.34	RECEPTOR_TYR_KIN_II	prosite domains	PS00239	11	1	12186	40	NTRK2
3.558e-02	-3.34	SH3	smart domains	SM00326	202	3	9717	35	KALRN,NEBL,SORBS1
3.559e-02	-3.34	Defective EXT2 causes exostoses 2	REACTOME pathways	R-HSA-3656237	12	1	10285	31	GPC5
3.559e-02	-3.34	Defective EXT1 causes exostoses 1, TRPS2 and CHDS	REACTOME pathways	R-HSA-3656253	12	1	10285	31	GPC5
3.560e-02	-3.34	MFAP5-mediated ovarian cancer cell motility and invasiveness	WikiPathways	WP3301	12	1	5310	16	RYR3
3.574e-02	-3.33	human chr5p15.2	chromosome location	human chr5p15.2	19	1	26134	50	CTNND2
3.574e-02	-3.33	human chr11q25	chromosome location	human chr11q25	19	1	26134	50	NTM
3.574e-02	-3.33	human chr6q24.1	chromosome location	human chr6q24.1	19	1	26134	50	NHSL1
3.590e-02	-3.33	-	gene3d domains	3.10.450.50	12	1	14470	44	CAMK2G
3.590e-02	-3.33	Alpha-catenin/vinculin-like	gene3d domains	1.20.120.230	12	1	14470	44	CTNNA2
3.598e-02	-3.32	response to endogenous stimulus	biological process	GO:0009719	1402	8	18204	50	RYR3,SLC1A2,SORBS1,PLCB1,TNC,NTRK2,ATP1A2,SOX5
3.603e-02	-3.32	active monoatomic ion transmembrane transporter activity	molecular function	GO:0022853	274	3	18094	48	SLC1A2,ATP1A2,SLC4A4
3.612e-02	-3.32	postsynapse organization	biological process	GO:0099173	109	2	18204	50	CTNND2,NRXN1
3.620e-02	-3.32	regulation of canonical Wnt signaling pathway	biological process	GO:0060828	265	3	18204	50	RBMS3,CTNND2,GPC5
3.621e-02	-3.32	regulation of nervous system development	biological process	GO:0051960	456	4	18204	50	PARD3,NRXN1,NTRK2,MACF1
3.623e-02	-3.32	regulation of cellular process	biological process	GO:0050794	11468	38	18204	50	DTNA,NRCAM,DPP6,GPC5,NRXN1,RYR3,CNTN1,FAT3,HPSE2,SLC1A2,MAPK10,ADCY2,FMN2,NAV3,RFX4,SYNE1,RBMS3,PLCB1,MSI2,KALRN,NRG3,CAMK2G,GPM6A,DGKG,TNC,MACF1,RORA,SLC4A4,TNIK,PARD3,PITPNC1,CTNNA2,SORBS1,DCLK2,CTNND2,NTRK2,SOX5,ATP1A2
3.627e-02	-3.32	Ion_trans	pfam domains	PF00520	109	2	17795	49	TRPM3,RYR3
3.630e-02	-3.32	positive regulation of biological process	biological process	GO:0048518	6326	24	18204	50	NRCAM,NRXN1,GPC5,SLC1A2,HPSE2,CNTN1,PLCB1,SYNE1,RBMS3,RFX4,FMN2,NAV3,GPM6A,TNC,TNIK,SLC4A4,RORA,MACF1,PARD3,SFXN5,SORBS1,ATP1A2,SOX5,NTRK2
3.631e-02	-3.32	neuronal cell body	cellular component	GO:0043025	489	4	19108	49	GPM6A,ATP1A2,NRXN1,CTNND2
3.633e-02	-3.32	env (Envelope surface glycoprotein gp160, precursor)	protein interactions	155971	1501	8	19454	50	MAPK10,TNC,MGAT4C,PLCB1,NTRK2,SLC1A2,ADCY2,CTNNA2
3.647e-02	-3.31	Dppa3 (developmental pluripotency-associated 3)	protein interactions	73708	284	3	19454	50	CAMK2G,ATP1A2,MSI2
3.652e-02	-3.31	L-glutamate transmembrane transporter activity	molecular function	GO:0005313	14	1	18094	48	SLC1A2
3.652e-02	-3.31	microtubule minus-end binding	molecular function	GO:0051011	14	1	18094	48	MACF1
3.656e-02	-3.31	testis-germ_cell_tumour-seminoma	COSMIC cancer mutations	testis-germ_cell_tumour-seminoma	648	5	16828	48	TNIK,NTRK2,CAMK2G,DCLK2,SYNE1
3.668e-02	-3.31	CAV1 (caveolin 1)	protein interactions	857	719	5	19454	50	PARD3,FMN2,MACF1,DTNA,TNIK
3.670e-02	-3.31	phosphatidylinositol binding	molecular function	GO:0035091	276	3	18094	48	PLCB1,PARD3,PITPNC1
3.672e-02	-3.30	positive regulation of cell junction assembly	biological process	GO:1901890	110	2	18204	50	NRXN1,NTRK2
3.677e-02	-3.30	bone-tibia-Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour	COSMIC cancer mutations	bone-tibia-Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour	649	5	16828	48	MACF1,ABLIM1,FAT3,TRPM3,TNIK
3.691e-02	-3.30	L1CAM interactions	REACTOME pathways	R-HSA-373760	101	2	10285	31	NRCAM,CNTN1
3.699e-02	-3.30	B4GALT2 (beta-1,4-galactosyltransferase 2)	protein interactions	8704	118	2	19454	50	FAT3,CAMK2G
3.715e-02	-3.29	Neurexin-like	interpro domains	IPR003585	14	1	18521	50	NRXN1
3.715e-02	-3.29	LDLR_classB_rpt	interpro domains	IPR000033	14	1	18521	50	LRP1B
3.735e-02	-3.29	urinary_tract	COSMIC cancer mutations	urinary_tract	14112	45	16828	48	ABLIM1,PITPNC1,SLC14A1,RORA,LSAMP,NRCAM,NEBL,GPM6A,NAV2,MGAT4C,SOX5,CAMK2G,LRP1B,TNIK,ADCY2,MACF1,GPC5,NAV3,FAT3,PLCB1,TNC,RFX4,KALRN,SYNE1,MSI2,DGKG,SORBS1,SLC1A2,SLC4A4,SFXN5,CTNND2,PARD3,TRPM3,ATP1A2,NTRK2,NRXN1,DCLK2,HPSE2,DPP6,CNTN1,NRG3,RYR3,FMN2,DTNA,NTM
3.735e-02	-3.29	bladder	COSMIC cancer mutations	bladder	14112	45	16828	48	DTNA,FMN2,NTM,RYR3,NRG3,DPP6,CNTN1,NRXN1,DCLK2,HPSE2,PARD3,ATP1A2,NTRK2,TRPM3,SFXN5,CTNND2,SORBS1,SLC1A2,SLC4A4,MSI2,RFX4,KALRN,SYNE1,DGKG,NAV3,ADCY2,MACF1,GPC5,PLCB1,TNC,FAT3,LRP1B,TNIK,CAMK2G,SOX5,NAV2,GPM6A,MGAT4C,NRCAM,RORA,LSAMP,NEBL,SLC14A1,PITPNC1,ABLIM1
3.747e-02	-3.28	Integrin-mediated Cell Adhesion	WikiPathways	WP185	103	2	5310	16	MAPK10,SORBS1
3.748e-02	-3.28	Developmental Biology	REACTOME pathways	R-HSA-1266738	1075	7	10285	31	NRCAM,CAMK2G,ABLIM1,CNTN1,CTNNA2,NRG3,KALRN
3.749e-02	-3.28	Trehalose Degradation	SMPDB pathways	SMP0000467	13	1	1369	4	ATP1A2
3.749e-02	-3.28	Succinate Signalling During Inflammation	SMPDB pathways	SMP0084634	13	1	1369	4	PLCB1
3.752e-02	-3.28	Progesterone-mediated oocyte maturation	KEGG pathways	hsa04914	92	2	7161	24	ADCY2,MAPK10
3.752e-02	-3.28	Progesterone-mediated oocyte maturation	KEGG pathways	ko04914	92	2	7161	24	MAPK10,ADCY2
3.756e-02	-3.28	ANKRD26 (ankyrin repeat domain containing 26)	protein interactions	22852	119	2	19454	50	NTRK2,PARD3
3.759e-02	-3.28	human chr11q14.3	chromosome location	human chr11q14.3	20	1	26134	50	FAT3
3.771e-02	-3.28	microtubule binding	molecular function	GO:0008017	279	3	18094	48	DCLK2,NAV3,MACF1
3.779e-02	-3.28	regulation of skeletal muscle adaptation	biological process	GO:0014733	14	1	18204	50	CAMK2G
3.779e-02	-3.28	negative regulation of sodium ion transmembrane transporter activity	biological process	GO:2000650	14	1	18204	50	ATP1A2
3.779e-02	-3.28	glutathione biosynthetic process	biological process	GO:0006750	14	1	18204	50	SLC1A2
3.779e-02	-3.28	interneuron migration	biological process	GO:1904936	14	1	18204	50	FAT3
3.779e-02	-3.28	regulation of mesenchymal cell apoptotic process	biological process	GO:2001053	14	1	18204	50	SYNE1
3.779e-02	-3.28	mechanosensory behavior	biological process	GO:0007638	14	1	18204	50	NRXN1
3.779e-02	-3.28	relaxation of cardiac muscle	biological process	GO:0055119	14	1	18204	50	ATP1A2
3.779e-02	-3.28	cellular response to forskolin	biological process	GO:1904322	14	1	18204	50	ADCY2
3.779e-02	-3.28	cellular response to purine-containing compound	biological process	GO:0071415	14	1	18204	50	RYR3
3.779e-02	-3.28	response to forskolin	biological process	GO:1904321	14	1	18204	50	ADCY2
3.780e-02	-3.28	axolemma	cellular component	GO:0030673	15	1	19108	49	SLC1A2
3.788e-02	-3.27	XIRP1 (xin actin binding repeat containing 1)	protein interactions	165904	15	1	19454	50	NEBL
3.788e-02	-3.27	TAFA5 (TAFA chemokine like family member 5)	protein interactions	25817	15	1	19454	50	NEBL
3.788e-02	-3.27	DEFB123 (defensin beta 123)	protein interactions	245936	15	1	19454	50	LRP1B
3.788e-02	-3.27	OLFM3 (olfactomedin 3)	protein interactions	118427	15	1	19454	50	LRP1B
3.788e-02	-3.27	PCSK1N (proprotein convertase subtilisin/kexin type 1 inhibitor)	protein interactions	27344	15	1	19454	50	MGAT4C
3.794e-02	-3.27	rhythmic process	biological process	GO:0048511	270	3	18204	50	MAPK10,NTRK2,RORA
3.810e-02	-3.27	CEP128 (centrosomal protein 128)	protein interactions	145508	289	3	19454	50	SORBS1,NEBL,ABLIM1
3.818e-02	-3.27	lung-middle_lobe-carcinoma-adenocarcinoma	COSMIC cancer mutations	lung-middle_lobe-carcinoma-adenocarcinoma	1368	8	16828	48	MACF1,RYR3,HPSE2,SYNE1,CTNND2,LRP1B,ATP1A2,TRPM3
3.843e-02	-3.26	nuclear envelope	cellular component	GO:0005635	498	4	19108	49	NAV3,SYNE1,PLCB1,NRXN1
3.850e-02	-3.26	ERBB2 Activates PTK6 Signaling	REACTOME pathways	R-HSA-8847993	13	1	10285	31	NRG3
3.855e-02	-3.26	solute:monoatomic cation symporter activity	molecular function	GO:0015294	117	2	18094	48	SLC1A2,SLC4A4
3.856e-02	-3.26	metencephalon development	biological process	GO:0022037	113	2	18204	50	RORA,CNTN1
3.870e-02	-3.25	MAPK	prosite domains	PS01351	12	1	12186	40	MAPK10
3.884e-02	-3.25	lung-carcinoma-adenocarcinoma	COSMIC cancer mutations	lung-carcinoma-adenocarcinoma	15133	47	16828	48	DGKG,MSI2,KALRN,SYNE1,RFX4,TNC,PLCB1,FAT3,NAV3,MACF1,GPC5,ADCY2,TNIK,LRP1B,CAMK2G,SOX5,MGAT4C,NAV2,GPM6A,NEBL,NRCAM,RORA,LSAMP,SLC14A1,NHSL1,PITPNC1,ABLIM1,NTM,FMN2,DTNA,RYR3,NRG3,NKAIN3,CNTN1,DPP6,HPSE2,DCLK2,NRXN1,NTRK2,ATP1A2,TRPM3,PARD3,CTNND2,SFXN5,SLC4A4,SLC1A2,SORBS1
3.887e-02	-3.25	positive regulation of multicellular organismal process	biological process	GO:0051240	1691	9	18204	50	PARD3,SFXN5,PLCB1,MACF1,NTRK2,RORA,NRXN1,SOX5,ATP1A2
3.893e-02	-3.25	Stimuli-sensing channels	REACTOME pathways	R-HSA-2672351	104	2	10285	31	RYR3,TRPM3
3.900e-02	-3.24	vascular process in circulatory system	biological process	GO:0003018	273	3	18204	50	SLC4A4,SLC1A2,ATP1A2
3.908e-02	-3.24	filamin binding	molecular function	GO:0031005	15	1	18094	48	NEBL
3.908e-02	-3.24	tropomyosin binding	molecular function	GO:0005523	15	1	18094	48	NEBL
3.908e-02	-3.24	3'-5' DNA helicase activity	molecular function	GO:0043138	15	1	18094	48	NAV2
3.908e-02	-3.24	low-density lipoprotein particle receptor activity	molecular function	GO:0005041	15	1	18094	48	LRP1B
3.908e-02	-3.24	phosphatidylglycerol binding	molecular function	GO:1901611	15	1	18094	48	PITPNC1
3.912e-02	-3.24	regulation of developmental process	biological process	GO:0050793	2540	12	18204	50	NRXN1,TNIK,MACF1,RORA,NRCAM,DGKG,SOX5,NTRK2,PLCB1,SYNE1,FAT3,PARD3
3.918e-02	-3.24	regulation of circadian rhythm	biological process	GO:0042752	114	2	18204	50	RORA,MAPK10
3.925e-02	-3.24	prostate-adenoma	COSMIC cancer mutations	prostate-adenoma	1634	9	16828	48	SYNE1,LRP1B,PARD3,TRPM3,SOX5,GPC5,MACF1,DCLK2,NEBL
3.930e-02	-3.24	BRK1 (BRICK1 subunit of SCAR/WAVE actin nucleating complex)	protein interactions	55845	122	2	19454	50	NHSL1,DTNA
3.930e-02	-3.24	SLMAP (sarcolemma associated protein)	protein interactions	7871	122	2	19454	50	TNIK,CAMK2G
3.943e-02	-3.23	human chr10q23.1	chromosome location	human chr10q23.1	21	1	26134	50	NRG3
3.943e-02	-3.23	human chr13q31.3	chromosome location	human chr13q31.3	21	1	26134	50	GPC5
3.947e-02	-3.23	EGF_CA	prosite domains	PS01187	96	2	12186	40	FAT3,LRP1B
3.971e-02	-3.23	gliogenesis	biological process	GO:0042063	275	3	18204	50	PARD3,CNTN1,NTRK2
3.975e-02	-3.23	CNH_dom	interpro domains	IPR001180	15	1	18521	50	TNIK
3.975e-02	-3.23	ATPase_P-typ_cation-transptr_C	interpro domains	IPR006068	15	1	18521	50	ATP1A2
3.975e-02	-3.23	Diacylglycerol_kinase_cat_dom	interpro domains	IPR001206	15	1	18521	50	DGKG
3.975e-02	-3.23	PI-PLC_fam	interpro domains	IPR001192	15	1	18521	50	PLCB1
3.975e-02	-3.23	NTF2-like_dom_sf	interpro domains	IPR032710	15	1	18521	50	CAMK2G
3.975e-02	-3.23	PLipase_C_Pinositol-sp_Y	interpro domains	IPR001711	15	1	18521	50	PLCB1
3.975e-02	-3.23	FH2_Formin_sf	interpro domains	IPR042201	15	1	18521	50	FMN2
3.975e-02	-3.23	FH2_Formin	interpro domains	IPR015425	15	1	18521	50	FMN2
3.978e-02	-3.22	Endocrine resistance	KEGG pathways	ko01522	95	2	7161	24	MAPK10,ADCY2
3.978e-02	-3.22	Endocrine resistance	KEGG pathways	hsa01522	95	2	7161	24	ADCY2,MAPK10
3.988e-02	-3.22	GNAQ (G protein subunit alpha q)	protein interactions	2776	123	2	19454	50	GPM6A,PLCB1
4.017e-02	-3.21	ovary-carcinoma-clear_cell_carcinoma	COSMIC cancer mutations	ovary-carcinoma-clear_cell_carcinoma	665	5	16828	48	NTRK2,TNIK,LRP1B,DCLK2,CAMK2G
4.019e-02	-3.21	middle_lobe	COSMIC cancer mutations	middle_lobe	1382	8	16828	48	MACF1,HPSE2,RYR3,LRP1B,SYNE1,CTNND2,TRPM3,ATP1A2
4.027e-02	-3.21	postsynaptic density, intracellular component	cellular component	GO:0099092	16	1	19108	49	TNIK
4.033e-02	-3.21	Pathways in cancer	KEGG pathways	hsa05200	395	4	7161	24	CTNNA2,PLCB1,MAPK10,ADCY2
4.035e-02	-3.21	SYTL2 (synaptotagmin like 2)	protein interactions	54843	16	1	19454	50	NRXN1
4.035e-02	-3.21	CDH12 (cadherin 12)	protein interactions	1010	16	1	19454	50	CTNNA2
4.035e-02	-3.21	CAMK1G (calcium/calmodulin dependent protein kinase IG)	protein interactions	57172	16	1	19454	50	CAMK2G
4.035e-02	-3.21	SAPCD1 (suppressor APC domain containing 1)	protein interactions	401251	16	1	19454	50	CTNNA2
4.035e-02	-3.21	GALNT13 (polypeptide N-acetylgalactosaminyltransferase 13)	protein interactions	114805	16	1	19454	50	TNIK
4.035e-02	-3.21	CNTNAP2 (contactin associated protein 2)	protein interactions	26047	16	1	19454	50	MACF1
4.035e-02	-3.21	SYT9 (synaptotagmin 9)	protein interactions	143425	16	1	19454	50	NRXN1
4.035e-02	-3.21	SYT4 (synaptotagmin 4)	protein interactions	6860	16	1	19454	50	NRXN1
4.035e-02	-3.21	AMMECR1L (AMMECR1 like)	protein interactions	83607	16	1	19454	50	MACF1
4.035e-02	-3.21	DUS1L (dihydrouridine synthase 1 like)	protein interactions	64118	16	1	19454	50	CAMK2G
4.043e-02	-3.21	protein homotrimerization	biological process	GO:0070207	15	1	18204	50	SLC1A2
4.043e-02	-3.21	peripheral nervous system neuron differentiation	biological process	GO:0048934	15	1	18204	50	NTRK2
4.043e-02	-3.21	sarcoplasmic reticulum calcium ion transport	biological process	GO:0070296	15	1	18204	50	RYR3
4.043e-02	-3.21	neuroblast division	biological process	GO:0055057	15	1	18204	50	SOX5
4.043e-02	-3.21	cerebellar Purkinje cell layer formation	biological process	GO:0021694	15	1	18204	50	RORA
4.043e-02	-3.21	positive regulation of glycogen biosynthetic process	biological process	GO:0045725	15	1	18204	50	SORBS1
4.043e-02	-3.21	pyramidal neuron differentiation	biological process	GO:0021859	15	1	18204	50	DCLK2
4.043e-02	-3.21	regulation of neuron projection arborization	biological process	GO:0150011	15	1	18204	50	MACF1
4.043e-02	-3.21	negative regulation of sodium ion transmembrane transport	biological process	GO:1902306	15	1	18204	50	ATP1A2
4.043e-02	-3.21	peripheral nervous system neuron development	biological process	GO:0048935	15	1	18204	50	NTRK2
4.043e-02	-3.21	intracellular potassium ion homeostasis	biological process	GO:0030007	15	1	18204	50	ATP1A2
4.043e-02	-3.21	response to caffeine	biological process	GO:0031000	15	1	18204	50	RYR3
4.053e-02	-3.21	CRAL_TRIO_2	pfam domains	PF13716	15	1	17795	49	KALRN
4.053e-02	-3.21	FH2	pfam domains	PF02181	15	1	17795	49	FMN2
4.053e-02	-3.21	Cation_ATPase_C	pfam domains	PF00689	15	1	17795	49	ATP1A2
4.053e-02	-3.21	DAGK_cat	pfam domains	PF00781	15	1	17795	49	DGKG
4.053e-02	-3.21	CNH	pfam domains	PF00780	15	1	17795	49	TNIK
4.053e-02	-3.21	PI-PLC-Y	pfam domains	PF00387	15	1	17795	49	PLCB1
4.059e-02	-3.20	ovary-carcinoma-mucinous_carcinoma	COSMIC cancer mutations	ovary-carcinoma-mucinous_carcinoma	456	4	16828	48	TNIK,NTRK2,CAMK2G,DCLK2
4.065e-02	-3.20	membrane protein complex	cellular component	GO:0098796	1261	7	19108	49	DPP6,SORBS1,RYR3,ATP1A2,SLC1A2,SYNE1,CTNNA2
4.079e-02	-3.20	TJP1 (tight junction protein 1)	protein interactions	7082	297	3	19454	50	NEBL,PARD3,DTNA
4.080e-02	-3.20	actin filament organization	biological process	GO:0007015	278	3	18204	50	NEBL,FMN2,SORBS1
4.099e-02	-3.19	Transport of inorganic cations/anions and amino acids/oligopeptides	REACTOME pathways	R-HSA-425393	107	2	10285	31	SLC4A4,SLC1A2
4.105e-02	-3.19	clear_cell_carcinoma	COSMIC cancer mutations	clear_cell_carcinoma	669	5	16828	48	LRP1B,CAMK2G,DCLK2,TNIK,NTRK2
4.107e-02	-3.19	regulation of synapse assembly	biological process	GO:0051963	117	2	18204	50	NRXN1,NTRK2
4.114e-02	-3.19	mucinous_carcinoma	COSMIC cancer mutations	mucinous_carcinoma	458	4	16828	48	NTRK2,TNIK,DCLK2,CAMK2G
4.127e-02	-3.19	human chr3q13.31	chromosome location	human chr3q13.31	22	1	26134	50	LSAMP
4.128e-02	-3.19	positive regulation of cellular process	biological process	GO:0048522	5719	22	18204	50	TNC,MACF1,RORA,SLC4A4,TNIK,GPM6A,SORBS1,NTRK2,SOX5,PARD3,GPC5,NRXN1,NRCAM,NAV3,FMN2,RBMS3,SYNE1,RFX4,PLCB1,CNTN1,SLC1A2,HPSE2
4.131e-02	-3.19	Phosphatidylinositol signaling system	KEGG pathways	hsa04070	97	2	7161	24	PLCB1,DGKG
4.131e-02	-3.19	Phosphatidylinositol signaling system	KEGG pathways	ko04070	97	2	7161	24	PLCB1,DGKG
4.141e-02	-3.18	SHC1 events in ERBB4 signaling	REACTOME pathways	R-HSA-1250347	14	1	10285	31	NRG3
4.141e-02	-3.18	DCC mediated attractive signaling	REACTOME pathways	R-HSA-418885	14	1	10285	31	ABLIM1
4.142e-02	-3.18	ERK Pathway in Huntington's Disease	WikiPathways	WP3853	14	1	5310	16	NTRK2
4.163e-02	-3.18	adenylate cyclase activity	molecular function	GO:0004016	16	1	18094	48	ADCY2
4.163e-02	-3.18	MAP kinase activity	molecular function	GO:0004707	16	1	18094	48	MAPK10
4.163e-02	-3.18	MAP kinase kinase activity	molecular function	GO:0004708	16	1	18094	48	MAPK10
4.163e-02	-3.18	oxysterol binding	molecular function	GO:0008142	16	1	18094	48	RORA
4.166e-02	-3.18	SYP (synaptophysin)	protein interactions	6855	126	2	19454	50	PITPNC1,GPM6A
4.176e-02	-3.18	-	gene3d domains	2.60.200.40	14	1	14470	44	DGKG
4.176e-02	-3.18	-	gene3d domains	2.20.25.10	14	1	14470	44	TNC
4.186e-02	-3.17	LDLRB	prosite domains	PS51120	13	1	12186	40	LRP1B
4.193e-02	-3.17	cell surface receptor signaling pathway	biological process	GO:0007166	1992	10	18204	50	MAPK10,CNTN1,NRG3,KALRN,TNIK,MACF1,CTNND2,NTRK2,PLCB1,SORBS1
4.193e-02	-3.17	response to stimulus	biological process	GO:0050896	7803	28	18204	50	NRXN1,DTNA,PLCB1,FMN2,SYNE1,RBMS3,RYR3,SLC1A2,MAPK10,ADCY2,CNTN1,TNC,TNIK,MACF1,RORA,NRG3,KALRN,GPM6A,DGKG,SORBS1,SOX5,ATP1A2,NTRK2,CTNND2,DCLK2,PARD3,CTNNA2,PITPNC1
4.209e-02	-3.17	Estrogen signaling pathway	KEGG pathways	hsa04915	98	2	7161	24	ADCY2,PLCB1
4.209e-02	-3.17	Estrogen signaling pathway	KEGG pathways	ko04915	98	2	7161	24	ADCY2,PLCB1
4.216e-02	-3.17	ARRB1 (arrestin beta 1)	protein interactions	408	301	3	19454	50	LRP1B,DGKG,MAPK10
4.230e-02	-3.16	EGF-like_Ca-bd_dom	interpro domains	IPR001881	121	2	18521	50	FAT3,LRP1B
4.265e-02	-3.15	Wnt signaling pathway	biological process	GO:0016055	283	3	18204	50	CTNND2,MACF1,TNIK
4.267e-02	-3.15	neuron projection terminus	cellular component	GO:0044306	128	2	19108	49	NTRK2,SLC1A2
4.273e-02	-3.15	protein complex involved in cell-matrix adhesion	cellular component	GO:0098637	17	1	19108	49	TNC
4.282e-02	-3.15	ovary-carcinoma-endometrioid_carcinoma	COSMIC cancer mutations	ovary-carcinoma-endometrioid_carcinoma	464	4	16828	48	CAMK2G,DCLK2,TNIK,NTRK2
4.282e-02	-3.15	DPP6 (dipeptidyl peptidase like 6)	protein interactions	1804	17	1	19454	50	GPM6A
4.282e-02	-3.15	SCN1B (sodium voltage-gated channel beta subunit 1)	protein interactions	6324	17	1	19454	50	CNTN1
4.282e-02	-3.15	PAX4 (paired box 4)	protein interactions	5078	17	1	19454	50	NTM
4.282e-02	-3.15	KRTAP19-3 (keratin associated protein 19-3)	protein interactions	337970	17	1	19454	50	CAMK2G
4.282e-02	-3.15	TAGAP (T cell activation RhoGTPase activating protein)	protein interactions	117289	17	1	19454	50	DTNA
4.282e-02	-3.15	NFASC (neurofascin)	protein interactions	23114	17	1	19454	50	NRCAM
4.282e-02	-3.15	Shcbp1 (Shc SH2-domain binding protein 1)	protein interactions	20419	17	1	19454	50	GPC5
4.282e-02	-3.15	SEPSECS (Sep (O-phosphoserine) tRNA:Sec (selenocysteine) tRNA synthase)	protein interactions	51091	17	1	19454	50	ABLIM1
4.282e-02	-3.15	MSANTD2 (Myb/SANT DNA binding domain containing 2)	protein interactions	79684	17	1	19454	50	SOX5
4.282e-02	-3.15	FAM163B (family with sequence similarity 163 member B)	protein interactions	642968	17	1	19454	50	CAMK2G
4.286e-02	-3.15	ATF7IP (activating transcription factor 7 interacting protein)	protein interactions	55729	128	2	19454	50	SOX5,MACF1
4.287e-02	-3.15	AGE-RAGE signaling pathway in diabetic complications	KEGG pathways	hsa04933	99	2	7161	24	MAPK10,PLCB1
4.287e-02	-3.15	Choline metabolism in cancer	KEGG pathways	ko05231	99	2	7161	24	MAPK10,DGKG
4.287e-02	-3.15	AGE-RAGE signaling pathway in diabetic complications	KEGG pathways	ko04933	99	2	7161	24	MAPK10,PLCB1
4.287e-02	-3.15	Choline metabolism in cancer	KEGG pathways	hsa05231	99	2	7161	24	MAPK10,DGKG
4.307e-02	-3.14	nonribosomal peptide biosynthetic process	biological process	GO:0019184	16	1	18204	50	SLC1A2
4.307e-02	-3.14	locomotory exploration behavior	biological process	GO:0035641	16	1	18204	50	ATP1A2
4.307e-02	-3.14	regulation of postsynaptic neurotransmitter receptor internalization	biological process	GO:0099149	16	1	18204	50	SYNE1
4.307e-02	-3.14	neuron cell-cell adhesion	biological process	GO:0007158	16	1	18204	50	NRXN1
4.307e-02	-3.14	regulation of respiratory system process	biological process	GO:0044065	16	1	18204	50	ATP1A2
4.307e-02	-3.14	response to ether	biological process	GO:0045472	16	1	18204	50	PLCB1
4.307e-02	-3.14	regulation of amino acid transmembrane transport	biological process	GO:1903789	16	1	18204	50	ATP1A2
4.307e-02	-3.14	regulation of amino acid import across plasma membrane	biological process	GO:0010958	16	1	18204	50	ATP1A2
4.311e-02	-3.14	human chr5p15.31	chromosome location	human chr5p15.31	23	1	26134	50	ADCY2
4.321e-02	-3.14	CARM1 (coactivator associated arginine methyltransferase 1)	protein interactions	10498	304	3	19454	50	RORA,DTNA,CAMK2G
4.366e-02	-3.13	channel activity	molecular function	GO:0015267	502	4	18094	48	SLC14A1,GPM6A,RYR3,TRPM3
4.379e-02	-3.13	regulation of transmembrane transport	biological process	GO:0034762	485	4	18204	50	ATP1A2,SLC1A2,DPP6,SORBS1
4.381e-02	-3.13	Integration of energy metabolism	REACTOME pathways	R-HSA-163685	111	2	10285	31	PLCB1,ADCY2
4.388e-02	-3.13	Z disc	cellular component	GO:0030018	130	2	19108	49	NEBL,RYR3
4.392e-02	-3.13	passive transmembrane transporter activity	molecular function	GO:0022803	503	4	18094	48	SLC14A1,GPM6A,TRPM3,RYR3
4.430e-02	-3.12	N-Glycan antennae elongation	REACTOME pathways	R-HSA-975577	15	1	10285	31	MGAT4C
4.430e-02	-3.12	Inhibition of adenylate cyclase pathway	REACTOME pathways	R-HSA-997269	15	1	10285	31	ADCY2
4.430e-02	-3.12	ERBB2 Regulates Cell Motility	REACTOME pathways	R-HSA-6785631	15	1	10285	31	NRG3
4.430e-02	-3.12	Adenylate cyclase inhibitory pathway	REACTOME pathways	R-HSA-170670	15	1	10285	31	ADCY2
4.467e-02	-3.11	Formin, FH2 domain	gene3d domains	1.20.58.2220	15	1	14470	44	FMN2
4.472e-02	-3.11	FCERI mediated MAPK activation	REACTOME pathways	R-HSA-2871796	265	3	10285	31	MAPK10,CAMK2G,NRG3
4.492e-02	-3.10	muscle cell differentiation	biological process	GO:0042692	289	3	18204	50	RORA,NEBL,SYNE1
4.493e-02	-3.10	ATP-NAD_kinase_N	interpro domains	IPR017438	17	1	18521	50	DGKG
4.493e-02	-3.10	PLipase_C_PInositol-sp_X_dom	interpro domains	IPR000909	17	1	18521	50	PLCB1
4.493e-02	-3.10	NAD/diacylglycerol_kinase_sf	interpro domains	IPR016064	17	1	18521	50	DGKG
4.493e-02	-3.10	A/G_cyclase_CS	interpro domains	IPR018297	17	1	18521	50	ADCY2
4.525e-02	-3.10	Chagas disease (American trypanosomiasis)	KEGG pathways	hsa05142	102	2	7161	24	PLCB1,MAPK10
4.525e-02	-3.10	Chagas disease (American trypanosomiasis)	KEGG pathways	ko05142	102	2	7161	24	PLCB1,MAPK10
4.529e-02	-3.09	Cnot2 (CCR4-NOT transcription complex, subunit 2)	protein interactions	72068	18	1	19454	50	MACF1
4.529e-02	-3.09	DCDC1 (doublecortin domain containing 1)	protein interactions	341019	18	1	19454	50	FAT3
4.529e-02	-3.09	ZNF224 (zinc finger protein 224)	protein interactions	7767	18	1	19454	50	LRP1B
4.529e-02	-3.09	OPCML (opioid binding protein/cell adhesion molecule like)	protein interactions	4978	18	1	19454	50	NTM
4.529e-02	-3.09	TTC29 (tetratricopeptide repeat domain 29)	protein interactions	83894	18	1	19454	50	MACF1
4.529e-02	-3.09	ACAP1 (ArfGAP with coiled-coil, ankyrin repeat and PH domains 1)	protein interactions	9744	18	1	19454	50	NEBL
4.529e-02	-3.09	ADAT2 (adenosine deaminase tRNA specific 2)	protein interactions	134637	18	1	19454	50	NAV2
4.529e-02	-3.09	DCANP1 (dendritic cell associated nuclear protein 1)	protein interactions	140947	18	1	19454	50	FAT3
4.529e-02	-3.09	NECTIN1 (nectin cell adhesion molecule 1)	protein interactions	5818	18	1	19454	50	PARD3
4.530e-02	-3.09	STRN (striatin)	protein interactions	6801	132	2	19454	50	CAMK2G,TNIK
4.560e-02	-3.09	cardiocyte differentiation	biological process	GO:0035051	124	2	18204	50	NEBL,SYNE1
4.570e-02	-3.09	positive regulation of glycogen metabolic process	biological process	GO:0070875	17	1	18204	50	SORBS1
4.570e-02	-3.09	branch elongation of an epithelium	biological process	GO:0060602	17	1	18204	50	TNC
4.570e-02	-3.09	regulation of fertilization	biological process	GO:0080154	17	1	18204	50	PLCB1
4.570e-02	-3.09	preganglionic parasympathetic fiber development	biological process	GO:0021783	17	1	18204	50	NAV2
4.570e-02	-3.09	retinal rod cell differentiation	biological process	GO:0060221	17	1	18204	50	NTRK2
4.570e-02	-3.09	protein trimerization	biological process	GO:0070206	17	1	18204	50	SLC1A2
4.570e-02	-3.09	cell migration in hindbrain	biological process	GO:0021535	17	1	18204	50	CTNNA2
4.570e-02	-3.09	cellular response to ATP	biological process	GO:0071318	17	1	18204	50	RYR3
4.570e-02	-3.09	positive regulation of meiotic nuclear division	biological process	GO:0045836	17	1	18204	50	PLCB1
4.570e-02	-3.09	microvillus assembly	biological process	GO:0030033	17	1	18204	50	TNIK
4.570e-02	-3.09	cGMP metabolic process	biological process	GO:0046068	17	1	18204	50	RORA
4.570e-02	-3.09	T-helper 17 type immune response	biological process	GO:0072538	17	1	18204	50	RORA
4.570e-02	-3.09	cell communication by electrical coupling involved in cardiac conduction	biological process	GO:0086064	17	1	18204	50	ATP1A2
4.570e-02	-3.09	membrane depolarization during cardiac muscle cell action potential	biological process	GO:0086012	17	1	18204	50	ATP1A2
4.581e-02	-3.08	PI-PLC-X	pfam domains	PF00388	17	1	17795	49	PLCB1
4.581e-02	-3.08	ZZ	pfam domains	PF00569	17	1	17795	49	DTNA
4.598e-02	-3.08	haematopoietic_and_lymphoid_tissue-abdomen-lymphoid_neoplasm-diffuse_large_B_cell_lymphoma	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue-abdomen-lymphoid_neoplasm-diffuse_large_B_cell_lymphoma	120	2	16828	48	FMN2,CTNND2
4.626e-02	-3.07	actomyosin structure organization	biological process	GO:0031032	125	2	18204	50	SORBS1,NEBL
4.626e-02	-3.07	cerebral cortex development	biological process	GO:0021987	125	2	18204	50	PLCB1,NTRK2
4.626e-02	-3.07	cellular component assembly involved in morphogenesis	biological process	GO:0010927	125	2	18204	50	NEBL,CNTN1
4.626e-02	-3.07	cellular anatomical entity morphogenesis	biological process	GO:0032989	125	2	18204	50	NEBL,CNTN1
4.653e-02	-3.07	MYO10 (myosin X)	protein interactions	4651	134	2	19454	50	CAMK2G,DPP6
4.671e-02	-3.06	phosphatidylcholine transporter activity	molecular function	GO:0008525	18	1	18094	48	PITPNC1
4.671e-02	-3.06	acidic amino acid transmembrane transporter activity	molecular function	GO:0015172	18	1	18094	48	SLC1A2
4.671e-02	-3.06	lipoprotein particle receptor activity	molecular function	GO:0030228	18	1	18094	48	LRP1B
4.671e-02	-3.06	intracellularly gated calcium channel activity	molecular function	GO:0015278	18	1	18094	48	RYR3
4.671e-02	-3.06	heparan sulfate proteoglycan binding	molecular function	GO:0043395	18	1	18094	48	HPSE2
4.671e-02	-3.06	transmembrane receptor protein tyrosine kinase activator activity	molecular function	GO:0030297	18	1	18094	48	NRG3
4.677e-02	-3.06	human chr20p12.3	chromosome location	human chr20p12.3	25	1	26134	50	PLCB1
4.677e-02	-3.06	human chr7q31.1	chromosome location	human chr7q31.1	25	1	26134	50	NRCAM
4.693e-02	-3.06	limbic system development	biological process	GO:0021761	126	2	18204	50	ATP1A2,DCLK2
4.716e-02	-3.05	Myo1c (myosin IC)	protein interactions	17913	135	2	19454	50	ABLIM1,CAMK2G
4.718e-02	-3.05	PKA activation	REACTOME pathways	R-HSA-163615	16	1	10285	31	ADCY2
4.718e-02	-3.05	GRB2 events in ERBB2 signaling	REACTOME pathways	R-HSA-1963640	16	1	10285	31	NRG3
4.718e-02	-3.05	PI3K events in ERBB2 signaling	REACTOME pathways	R-HSA-1963642	16	1	10285	31	NRG3
4.750e-02	-3.05	anatomical structure formation involved in morphogenesis	biological process	GO:0048646	964	6	18204	50	NRG3,NEBL,NRCAM,CNTN1,FAT3,RORA
4.752e-02	-3.05	A/G_cyclase	interpro domains	IPR001054	18	1	18521	50	ADCY2
4.752e-02	-3.05	Nucleotide_cyclase	interpro domains	IPR029787	18	1	18521	50	ADCY2
4.752e-02	-3.05	ATPase_P-typ_cation-transptr_N	interpro domains	IPR004014	18	1	18521	50	ATP1A2
4.760e-02	-3.05	response to amino acid	biological process	GO:0043200	127	2	18204	50	NTRK2,SLC1A2
4.764e-02	-3.04	astrocyte projection	cellular component	GO:0097449	19	1	19108	49	SLC1A2
4.764e-02	-3.04	postsynaptic specialization, intracellular component	cellular component	GO:0099091	19	1	19108	49	TNIK
4.764e-02	-3.04	cation-transporting ATPase complex	cellular component	GO:0090533	19	1	19108	49	ATP1A2
4.764e-02	-3.04	cytosolic region	cellular component	GO:0099522	19	1	19108	49	PLCB1
4.764e-02	-3.04	parallel fiber to Purkinje cell synapse	cellular component	GO:0098688	19	1	19108	49	GPM6A
4.764e-02	-3.04	positive regulation of nervous system development	biological process	GO:0051962	296	3	18204	50	NRXN1,NTRK2,MACF1
4.774e-02	-3.04	CNTNAP4 (contactin associated protein family member 4)	protein interactions	85445	19	1	19454	50	MACF1
4.774e-02	-3.04	SYT7 (synaptotagmin 7)	protein interactions	9066	19	1	19454	50	NRXN1
4.774e-02	-3.04	TNR (tenascin R)	protein interactions	7143	19	1	19454	50	CNTN1
4.774e-02	-3.04	C3orf62 (chromosome 3 open reading frame 62)	protein interactions	375341	19	1	19454	50	ATP1A2
4.774e-02	-3.04	EGFL6 (EGF like domain multiple 6)	protein interactions	25975	19	1	19454	50	LRP1B
4.774e-02	-3.04	RIT2 (Ras like without CAAX 2)	protein interactions	6014	19	1	19454	50	DTNA
4.774e-02	-3.04	OSM (oncostatin M)	protein interactions	5008	19	1	19454	50	TRPM3
4.774e-02	-3.04	RRAD (RRAD, Ras related glycolysis inhibitor and calcium channel regulator)	protein interactions	6236	19	1	19454	50	CAMK2G
4.774e-02	-3.04	PLCB2 (phospholipase C beta 2)	protein interactions	5330	19	1	19454	50	PLCB1
4.774e-02	-3.04	PHYHIPL (phytanoyl-CoA 2-hydroxylase interacting protein like)	protein interactions	84457	19	1	19454	50	GPM6A
4.774e-02	-3.04	GCHFR (GTP cyclohydrolase I feedback regulator)	protein interactions	2644	19	1	19454	50	NEBL
4.774e-02	-3.04	Mtx1 (metaxin 1)	protein interactions	17827	19	1	19454	50	CAMK2G
4.774e-02	-3.04	LTC4S (leukotriene C4 synthase)	protein interactions	4056	19	1	19454	50	CAMK2G
4.774e-02	-3.04	NLGN1 (neuroligin 1)	protein interactions	22871	19	1	19454	50	NRXN1
4.774e-02	-3.04	SPZ1 (spermatogenic leucine zipper 1)	protein interactions	84654	19	1	19454	50	DTNA
4.774e-02	-3.04	Trp53 (transformation related protein 53)	protein interactions	22059	19	1	19454	50	MAPK10
4.775e-02	-3.04	PHPHLIPASEC	prints domains	PR00390	15	1	5227	17	PLCB1
4.802e-02	-3.04	ductal_carcinoma	COSMIC cancer mutations	ductal_carcinoma	15798	48	16828	48	KALRN,SYNE1,RFX4,MSI2,DGKG,GPC5,MACF1,ADCY2,NAV3,FAT3,TNC,PLCB1,LRP1B,TNIK,SOX5,RBMS3,CAMK2G,GPM6A,NAV2,MGAT4C,LSAMP,RORA,NRCAM,NEBL,PITPNC1,NHSL1,SLC14A1,ABLIM1,NTM,FMN2,DTNA,NKAIN3,NRG3,RYR3,DPP6,CNTN1,DCLK2,NRXN1,HPSE2,PARD3,TRPM3,NTRK2,ATP1A2,CTNND2,SFXN5,SORBS1,SLC4A4,SLC1A2
4.804e-02	-3.04	carboxylic acid transport	biological process	GO:0046942	297	3	18204	50	NTRK2,SLC1A2,SFXN5
4.804e-02	-3.04	muscle system process	biological process	GO:0003012	297	3	18204	50	RYR3,ATP1A2,DTNA
4.806e-02	-3.04	bone-humerus-chondrosarcoma	COSMIC cancer mutations	bone-humerus-chondrosarcoma	123	2	16828	48	LRP1B,KALRN
4.815e-02	-3.03	DAGK	prosite domains	PS50146	15	1	12186	40	DGKG
4.815e-02	-3.03	FH2	prosite domains	PS51444	15	1	12186	40	FMN2
4.815e-02	-3.03	PIPLC_Y_DOMAIN	prosite domains	PS50008	15	1	12186	40	PLCB1
4.815e-02	-3.03	CNH	prosite domains	PS50219	15	1	12186	40	TNIK
4.831e-02	-3.03	regulation of signaling	biological process	GO:0023051	3534	15	18204	50	TNIK,NRXN1,RORA,GPC5,MACF1,DGKG,NRG3,KALRN,ATP1A2,CTNND2,NTRK2,PLCB1,SYNE1,RBMS3,SORBS1
4.832e-02	-3.03	regulation of acrosome reaction	biological process	GO:0060046	18	1	18204	50	PLCB1
4.832e-02	-3.03	cardiac myofibril assembly	biological process	GO:0055003	18	1	18204	50	NEBL
4.832e-02	-3.03	regulation of endothelial cell development	biological process	GO:1901550	18	1	18204	50	PLCB1
4.832e-02	-3.03	positive regulation of circadian rhythm	biological process	GO:0042753	18	1	18204	50	RORA
4.832e-02	-3.03	regulation of protein kinase C signaling	biological process	GO:0090036	18	1	18204	50	DGKG
4.832e-02	-3.03	negative regulation of anoikis	biological process	GO:2000811	18	1	18204	50	NTRK2
4.832e-02	-3.03	regulation of establishment of endothelial barrier	biological process	GO:1903140	18	1	18204	50	PLCB1
4.832e-02	-3.03	dendritic spine morphogenesis	biological process	GO:0060997	18	1	18204	50	CTNND2
4.832e-02	-3.03	negative regulation of sodium ion transport	biological process	GO:0010766	18	1	18204	50	ATP1A2
4.832e-02	-3.03	positive regulation of myelination	biological process	GO:0031643	18	1	18204	50	PARD3
4.842e-02	-3.03	TBL1X (transducin beta like 1 X-linked)	protein interactions	6907	137	2	19454	50	SOX5,DGKG
4.843e-02	-3.03	organic acid transport	biological process	GO:0015849	298	3	18204	50	SLC1A2,SFXN5,NTRK2
4.844e-02	-3.03	Cation_ATPase_N	pfam domains	PF00690	18	1	17795	49	ATP1A2
4.844e-02	-3.03	Guanylate_cyc	pfam domains	PF00211	18	1	17795	49	ADCY2
4.859e-02	-3.02	human chr18q12.1	chromosome location	human chr18q12.1	26	1	26134	50	DTNA
4.892e-02	-3.02	protein phosphorylation	biological process	GO:0006468	503	4	18204	50	MAPK10,TNIK,NTRK2,KALRN
4.905e-02	-3.01	regulation of cell communication	biological process	GO:0010646	3541	15	18204	50	NRG3,KALRN,DGKG,NRXN1,TNIK,GPC5,MACF1,RORA,PLCB1,SORBS1,SYNE1,RBMS3,ATP1A2,CTNND2,NTRK2
4.921e-02	-3.01	cellular response to hormone stimulus	biological process	GO:0032870	504	4	18204	50	ATP1A2,SORBS1,TNC,PLCB1
4.924e-02	-3.01	alkali metal ion binding	molecular function	GO:0031420	19	1	18094	48	ATP1A2
4.924e-02	-3.01	ankyrin binding	molecular function	GO:0030506	19	1	18094	48	NRCAM
4.924e-02	-3.01	water transmembrane transporter activity	molecular function	GO:0005372	19	1	18094	48	SLC14A1
4.930e-02	-3.01	DAGKc	smart domains	SM00046	14	1	9717	35	DGKG
4.930e-02	-3.01	CNH	smart domains	SM00036	14	1	9717	35	TNIK
4.930e-02	-3.01	4.1m	smart domains	SM00294	14	1	9717	35	NRXN1
4.930e-02	-3.01	LY	smart domains	SM00135	14	1	9717	35	LRP1B
4.931e-02	-3.01	Th17 cell differentiation	KEGG pathways	ko04659	107	2	7161	24	RORA,MAPK10
4.931e-02	-3.01	Th17 cell differentiation	KEGG pathways	hsa04659	107	2	7161	24	MAPK10,RORA
4.940e-02	-3.01	ACTA1 (actin alpha 1, skeletal muscle)	protein interactions	58	321	3	19454	50	SORBS1,DTNA,MACF1
4.951e-02	-3.01	cellular response to organonitrogen compound	biological process	GO:0071417	505	4	18204	50	SLC1A2,SORBS1,RYR3,PLCB1
4.963e-02	-3.00	medullary_carcinoma	COSMIC cancer mutations	medullary_carcinoma	290	3	16828	48	SLC1A2,NRG3,KALRN
4.963e-02	-3.00	thyroid-carcinoma-medullary_carcinoma	COSMIC cancer mutations	thyroid-carcinoma-medullary_carcinoma	290	3	16828	48	NRG3,SLC1A2,KALRN
4.968e-02	-3.00	SPCS2 (signal peptidase complex subunit 2)	protein interactions	9789	139	2	19454	50	GPC5,MGAT4C
4.999e-02	-3.00	regulation of biological quality	biological process	GO:0065008	2936	13	18204	50	NRCAM,DGKG,GPM6A,CAMK2G,NAV2,NRXN1,SLC4A4,MACF1,CTNNA2,ATP1A2,NTRK2,PLCB1,SYNE1