Gene Ontology Enrichment Results

Homer de novo Motif Enrichment Results
Known Motif Enrichment Results

Text file version of complete results (i.e. open with Excel)

biological process: Functional groupings of proteins (Gene Ontology)

molecular function: Mechanistic actions of proteins (Gene Ontology)

cellular component: Protein localization (Gene Ontology)

chromosome location: Genes with similar chromosome localization (NCBI Gene)

KEGG pathways: Groups of proteins in the same pathways (KEGG)

protein interactions: "Proteins interacting with a common protein (BIND, EcoCyc, HPRD)" (NCBI Gene)

interpro domains: Proteins with similar domains and features (Interpro)

pfam domains: Proteins with similar domains and features (Pfam)

smart domains: Proteins with similar domains and features (SMART)

gene3d domains: Proteins with similar domains and features (Gene3D)

prosite domains: Proteins with similar domains and features (Prosite)

prints domains: Proteins with similar domains and features (PRINTS)

MSigDB lists: "Genes sets for pathways, factor/miRNA target predictions, expression patterns, etc." (MSigDB)

BIOCYC pathways: Groups of proteins in the same pathways (BIOCYC)

COSMIC cancer mutations: Genes mutated in similar cancers (COSMIC)

GWAS genes: Genes mutated in similar diseases (GWAS Catalog)

Lipid Maps pathways: Groups of proteins in the same lipid pathways (Lipid Maps/Biosystems)

Pathway Interaction DB: Groups of proteins in the same pathways (Pathway Interaction Database)

REACTOME pathways: Groups of proteins in the same pathways (REACTOME)

SMPDB pathways: Groups of proteins in the same pathways (SMPDB)

WikiPathways: Groups of proteins in the same pathways (Wikipathways)

Enriched Categories

P-value	ln(P)	Term	GO Tree	GO ID	# of Genes in Term	# of Target Genes in Term	# of Total Genes	# of Target Genes	Common Genes
6.230e-10	-21.20	central_nervous_system-brain-primitive_neuroectodermal_tumour-medulloblastoma	COSMIC cancer mutations	central_nervous_system-brain-primitive_neuroectodermal_tumour-medulloblastoma	7205	42	16828	49	ABLIM1,MACF1,PCDH9,ITPR2,LSAMP,RORA,GPM6A,GPC5,SFXN5,NKAIN3,COL5A3,NFIA,TRPS1,PTPRZ1,PITPNC1,ZNF98,FBXL7,SOX5,TNIK,ATP13A4,FGFR3,NCKAP5,RFX4,LRIG1,ACSS1,NTM,ZBTB20,SLC1A3,NRXN1,PARD3B,CADM1,NPAS3,ERBB4,SLC1A2,AHCYL2,QKI,CTNND2,MAML2,RYR3,SLC4A4,NHSL1,PREX2
1.266e-09	-20.49	upper_aerodigestive_tract-mouth-carcinoma-squamous_cell_carcinoma	COSMIC cancer mutations	upper_aerodigestive_tract-mouth-carcinoma-squamous_cell_carcinoma	6953	41	16828	49	TNIK,SOX5,HIF3A,FBXL7,PITPNC1,ZNF98,TRPS1,PTPRZ1,CDH20,SFXN5,GPC5,RORA,GPM6A,ABLIM1,MACF1,PCDH9,ITPR2,LSAMP,PREX2,SLC4A4,NHSL1,MAML2,RYR3,SLC1A2,QKI,CTNND2,ERBB4,CADM1,PARD3B,NRXN1,ATP1A2,DTNA,ZBTB20,NTM,LRIG1,ACSS1,RFX4,CST3,NCKAP5,ATP13A4,FGFR3
1.647e-09	-20.22	brainstem	COSMIC cancer mutations	brainstem	3102	28	16828	49	GPM6A,RORA,LSAMP,ITPR2,PCDH9,NKAIN3,SFXN5,GPC5,PTPRZ1,CDH20,TNIK,SOX5,FBXL7,NCKAP5,FGFR3,ATP13A4,SLC1A3,ZBTB20,CTNND2,QKI,AHCYL2,SLC1A2,NPAS3,ERBB4,CADM1,PREX2,MAML2,RYR3
3.796e-09	-19.39	central_nervous_system-brainstem-glioma-astrocytoma_Grade_IV	COSMIC cancer mutations	central_nervous_system-brainstem-glioma-astrocytoma_Grade_IV	2531	25	16828	49	GPM6A,RORA,PCDH9,LSAMP,ITPR2,NKAIN3,SFXN5,GPC5,PTPRZ1,CDH20,TNIK,SOX5,FBXL7,NCKAP5,ATP13A4,SLC1A3,ZBTB20,CTNND2,AHCYL2,QKI,ERBB4,CADM1,PREX2,RYR3,MAML2
3.883e-09	-19.37	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-Burkitt_lymphoma	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-Burkitt_lymphoma	2119	23	16828	49	LRIG1,GPC5,NKAIN3,SLC1A3,ATP13A4,NCKAP5,PCDH9,LSAMP,ITPR2,GPM6A,RFX4,MAML2,RYR3,FBXL7,NHSL1,SOX5,PREX2,CADM1,NPAS3,ERBB4,SLC1A2,AHCYL2,CTNND2
3.883e-09	-19.37	Burkitt_lymphoma	COSMIC cancer mutations	Burkitt_lymphoma	2119	23	16828	49	GPM6A,ITPR2,LSAMP,PCDH9,NKAIN3,GPC5,FBXL7,SOX5,RFX4,ATP13A4,NCKAP5,SLC1A3,LRIG1,NPAS3,ERBB4,AHCYL2,CTNND2,SLC1A2,CADM1,PREX2,MAML2,RYR3,NHSL1
1.790e-08	-17.84	lymph_node	COSMIC cancer mutations	lymph_node	1703	20	16828	49	GPM6A,PCDH9,LSAMP,ITPR2,ATP13A4,FGFR3,SLC1A3,DTNA,SFXN5,ACSS1,GPC5,CTNND2,TRPS1,ERBB4,CADM1,PARD3B,TNIK,SOX5,RYR3,MAML2
1.793e-08	-17.84	haematopoietic_and_lymphoid_tissue-haematopoietic_neoplasm-acute_myeloid_leukaemia_therapy_related	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue-haematopoietic_neoplasm-acute_myeloid_leukaemia_therapy_related	1523	19	16828	49	NKAIN3,SLC1A3,COL5A3,ACSS1,GPC5,RORA,NCKAP5,PCDH9,LSAMP,ITPR2,PREX2,RYR3,MAML2,FBXL7,SOX5,ERBB4,CTNND2,QKI,CADM1
1.793e-08	-17.84	acute_myeloid_leukaemia_therapy_related	COSMIC cancer mutations	acute_myeloid_leukaemia_therapy_related	1523	19	16828	49	ERBB4,CTNND2,QKI,CADM1,PREX2,FBXL7,RYR3,MAML2,SOX5,RORA,ITPR2,LSAMP,PCDH9,NCKAP5,NKAIN3,COL5A3,SLC1A3,GPC5,ACSS1
2.157e-08	-17.65	haematopoietic_and_lymphoid_tissue-haematopoietic_neoplasm	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue-haematopoietic_neoplasm	764	14	16828	49	LSAMP,NCKAP5,PCDH9,COL5A3,ATP1A2,NKAIN3,GPC5,SLC1A2,ERBB4,PREX2,SOX5,FBXL7,RYR3,MAML2
2.342e-08	-17.57	cerebellum	COSMIC cancer mutations	cerebellum	769	14	16828	49	GPC5,ITPR2,PCDH9,ABLIM1,RYR3,MAML2,NRXN1,PARD3B,CADM1,PTPRZ1,ERBB4,NPAS3,QKI,CTNND2
4.276e-08	-16.97	acute_lymphoblastic_B_cell_leukaemia	COSMIC cancer mutations	acute_lymphoblastic_B_cell_leukaemia	3828	29	16828	49	GPM6A,RORA,ITPR2,LSAMP,PCDH9,NKAIN3,COL5A3,GPC5,PTPRZ1,NFIA,ZNF98,TNIK,FBXL7,HIF3A,SOX5,ATP13A4,NCKAP5,ZBTB20,SLC1A3,NTM,ERBB4,CTNND2,SLC1A2,NRXN1,CADM1,PREX2,RYR3,MAML2,SLC4A4
4.276e-08	-16.97	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-acute_lymphoblastic_B_cell_leukaemia	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-acute_lymphoblastic_B_cell_leukaemia	3828	29	16828	49	RORA,GPM6A,PCDH9,ITPR2,LSAMP,NKAIN3,COL5A3,GPC5,NFIA,PTPRZ1,ZNF98,TNIK,FBXL7,HIF3A,SOX5,ATP13A4,NCKAP5,ZBTB20,SLC1A3,NTM,ERBB4,SLC1A2,CTNND2,NRXN1,CADM1,PREX2,MAML2,RYR3,SLC4A4
4.446e-08	-16.93	mantle_cell_lymphoma	COSMIC cancer mutations	mantle_cell_lymphoma	2849	25	16828	49	LSAMP,ITPR2,PCDH9,NCKAP5,ATP13A4,RFX4,GPM6A,SFXN5,GPC5,LRIG1,SLC1A3,NKAIN3,CADM1,PARD3B,CTNND2,ZNF98,SLC1A2,ERBB4,TRPS1,HIF3A,SOX5,FBXL7,RYR3,MAML2,PREX2
5.023e-08	-16.81	prostate-carcinoma	COSMIC cancer mutations	prostate-carcinoma	9000	44	16828	49	FBXL7,HIF3A,TNIK,CDH20,NFIA,PTPRZ1,PITPNC1,PCDH9,MACF1,ITPR2,LSAMP,GPM6A,RYR3,NHSL1,SLC4A4,CADM1,LRIG1,NTM,ZBTB20,SLC1A3,DTNA,SOX5,TRPS1,GPC5,SFXN5,NKAIN3,COL5A3,ABLIM1,RORA,MAML2,PREX2,PARD3B,NRXN1,ERBB4,NPAS3,SLC1A2,CTNND2,QKI,AHCYL2,ATP13A4,FGFR3,NCKAP5,MSI2,RFX4
5.110e-08	-16.79	mouth	COSMIC cancer mutations	mouth	9004	44	16828	49	CDH20,PITPNC1,ZNF98,PTPRZ1,HIF3A,FBXL7,TNIK,MACF1,PCDH9,LSAMP,ITPR2,GPM6A,CADM1,SLC4A4,NHSL1,RYR3,NTM,LRIG1,SLC1A3,DTNA,ATP1A2,ZBTB20,TRPS1,SOX5,ABLIM1,RORA,SFXN5,GPC5,COL5A3,PARD3B,NRXN1,SLC1A2,CTNND2,QKI,ERBB4,NPAS3,MAML2,PREX2,NCKAP5,ATP13A4,FGFR3,RFX4,CST3,ACSS1
5.958e-08	-16.64	diffuse_large_B_cell_lymphoma	COSMIC cancer mutations	diffuse_large_B_cell_lymphoma	4151	30	16828	49	DTNA,ATP1A2,SLC1A3,ACSS1,FGFR3,ATP13A4,NCKAP5,PREX2,RYR3,MAML2,ERBB4,AHCYL2,CTNND2,QKI,SLC1A2,CADM1,NKAIN3,GPC5,RORA,GPM6A,LSAMP,ITPR2,PCDH9,MACF1,TNIK,FBXL7,SOX5,TRPS1,ZNF98,CDH20
8.769e-08	-16.25	nervous system development	biological process	GO:0007399	2185	21	18204	50	GPM6A,PTPRZ1,ATP1A2,CTNNA2,SLC1A2,CTNND2,NRXN1,PCDH9,ERBB4,RORA,RFX4,PREX2,NTM,SLC1A3,MSI2,SOX5,TNIK,QKI,LSAMP,LRIG1,NFIA
9.120e-08	-16.21	haematopoietic_and_lymphoid_tissue-lymph_node-lymphoid_neoplasm-mantle_cell_lymphoma	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue-lymph_node-lymphoid_neoplasm-mantle_cell_lymphoma	476	11	16828	49	RYR3,MAML2,ERBB4,CTNND2,CADM1,GPC5,SFXN5,GPM6A,ATP13A4,PCDH9,LSAMP
1.027e-07	-16.09	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-mantle_cell_lymphoma	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-mantle_cell_lymphoma	2737	24	16828	49	PREX2,RYR3,MAML2,ERBB4,CTNND2,SLC1A2,PARD3B,CADM1,SLC1A3,LRIG1,RFX4,NCKAP5,FBXL7,SOX5,HIF3A,TRPS1,ZNF98,NKAIN3,GPC5,SFXN5,GPM6A,ITPR2,LSAMP,PCDH9
2.603e-07	-15.16	central_nervous_system-cerebellum-primitive_neuroectodermal_tumour-medulloblastoma-SHH_subtype	COSMIC cancer mutations	central_nervous_system-cerebellum-primitive_neuroectodermal_tumour-medulloblastoma-SHH_subtype	653	12	16828	49	NRXN1,PARD3B,CADM1,ERBB4,NPAS3,PTPRZ1,CTNND2,MAML2,RYR3,ABLIM1,PCDH9,ITPR2
2.608e-07	-15.16	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-diffuse_large_B_cell_lymphoma	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-diffuse_large_B_cell_lymphoma	3608	27	16828	49	ACSS1,ATP1A2,NCKAP5,ATP13A4,FGFR3,RYR3,MAML2,PREX2,CADM1,SLC1A2,QKI,AHCYL2,CTNND2,ERBB4,GPC5,NKAIN3,MACF1,PCDH9,ITPR2,LSAMP,GPM6A,RORA,SOX5,FBXL7,TNIK,CDH20,ZNF98
2.646e-07	-15.15	SHH_subtype	COSMIC cancer mutations	SHH_subtype	654	12	16828	49	ITPR2,ABLIM1,PCDH9,NRXN1,PARD3B,CADM1,ERBB4,PTPRZ1,NPAS3,CTNND2,RYR3,MAML2
2.732e-07	-15.11	blood_vessel	COSMIC cancer mutations	blood_vessel	2211	21	16828	49	PREX2,MAML2,RYR3,FBXL7,SOX5,PTPRZ1,ERBB4,SLC1A2,CTNND2,CDH20,CADM1,NKAIN3,SLC1A3,COL5A3,GPC5,GPM6A,FGFR3,NCKAP5,PCDH9,LSAMP,ITPR2
2.894e-07	-15.06	chondroblastoma	COSMIC cancer mutations	chondroblastoma	534	11	16828	49	RYR3,SOX5,CTNND2,AHCYL2,NKAIN3,GPC5,SFXN5,GPM6A,NCKAP5,PCDH9,LSAMP
3.797e-07	-14.78	pharynx	COSMIC cancer mutations	pharynx	2696	23	16828	49	DTNA,ATP1A2,RFX4,NCKAP5,FGFR3,ATP13A4,PREX2,SLC4A4,NHSL1,RYR3,CTNND2,QKI,SLC1A2,NPAS3,PARD3B,SFXN5,GPC5,MACF1,PCDH9,ZNF98,PITPNC1,PTPRZ1,NFIA
4.013e-07	-14.73	PRNP (prion protein (Kanno blood group))	protein interactions	5621	1118	14	19454	49	MSI2,SLC4A4,SLC1A3,AHCYL2,PTPRZ1,LSAMP,TRPS1,QKI,ATP1A2,ABLIM1,MACF1,NHSL1,GPM6A,MAML2
5.309e-07	-14.45	oesophagus-carcinoma	COSMIC cancer mutations	oesophagus-carcinoma	4269	29	16828	49	GPM6A,PTGDS,ITPR2,PCDH9,MACF1,COL5A3,PTPRZ1,NFIA,TRPS1,CDH20,TNIK,FBXL7,HIF3A,SOX5,RFX4,FGFR3,ATP13A4,NCKAP5,ZBTB20,ACSS1,LRIG1,NTM,CTNND2,PARD3B,CADM1,PREX2,RYR3,SLC4A4,NHSL1
6.811e-07	-14.20	haematopoietic_and_lymphoid_tissue-haematopoietic_neoplasm-myelodysplastic_syndrome	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue-haematopoietic_neoplasm-myelodysplastic_syndrome	1174	15	16828	49	COL5A3,ATP1A2,NKAIN3,LSAMP,NCKAP5,FGFR3,TNIK,PREX2,SOX5,FBXL7,RYR3,SLC1A2,NPAS3,ERBB4,NFIA
6.811e-07	-14.20	myelodysplastic_syndrome	COSMIC cancer mutations	myelodysplastic_syndrome	1174	15	16828	49	SLC1A2,NFIA,NPAS3,ERBB4,SOX5,RYR3,FBXL7,TNIK,PREX2,NCKAP5,LSAMP,FGFR3,ATP1A2,COL5A3,NKAIN3
8.806e-07	-13.94	upper_aerodigestive_tract-larynx-carcinoma-squamous_cell_carcinoma	COSMIC cancer mutations	upper_aerodigestive_tract-larynx-carcinoma-squamous_cell_carcinoma	1946	19	16828	49	GPM6A,RORA,ITPR2,PCDH9,MACF1,NCKAP5,FGFR3,COL5A3,ZBTB20,AHCYL2,ERBB4,NPAS3,NRXN1,PARD3B,TNIK,SOX5,SLC4A4,RYR3,MAML2
8.947e-07	-13.93	larynx	COSMIC cancer mutations	larynx	1948	19	16828	49	NPAS3,ERBB4,AHCYL2,PARD3B,NRXN1,TNIK,MAML2,RYR3,SLC4A4,SOX5,RORA,GPM6A,FGFR3,NCKAP5,MACF1,PCDH9,ITPR2,ZBTB20,COL5A3
1.129e-06	-13.69	system development	biological process	GO:0048731	3533	25	18204	50	LSAMP,QKI,NFIA,SLC1A3,SOX5,MSI2,CADM1,CTNND2,GPM6A,ATP1A2,LRIG1,TNIK,NTM,RFX4,PREX2,ERBB4,RORA,PCDH9,TRPS1,SLC1A2,NRXN1,HIF3A,PTPRZ1,CTNNA2,FGFR3
1.170e-06	-13.66	soft_tissue-blood_vessel-angiosarcoma	COSMIC cancer mutations	soft_tissue-blood_vessel-angiosarcoma	2192	20	16828	49	PREX2,MAML2,RYR3,FBXL7,SOX5,PTPRZ1,ERBB4,SLC1A2,CTNND2,CDH20,CADM1,NKAIN3,SLC1A3,COL5A3,GPC5,GPM6A,NCKAP5,PCDH9,ITPR2,LSAMP
1.170e-06	-13.66	angiosarcoma	COSMIC cancer mutations	angiosarcoma	2192	20	16828	49	GPC5,SLC1A3,COL5A3,NKAIN3,PCDH9,NCKAP5,ITPR2,LSAMP,GPM6A,SOX5,RYR3,MAML2,FBXL7,PREX2,CADM1,CDH20,SLC1A2,CTNND2,PTPRZ1,ERBB4
1.677e-06	-13.30	bone	COSMIC cancer mutations	bone	8157	40	16828	49	COL5A3,NKAIN3,SFXN5,GPC5,RORA,GPM6A,ITPR2,LSAMP,ABLIM1,PCDH9,MACF1,PTGDS,TNIK,HIF3A,SOX5,ZNF98,PTPRZ1,TRPS1,DTNA,SLC1A3,ATP1A2,ZBTB20,ACSS1,LRIG1,CST3,NCKAP5,FGFR3,ATP13A4,PREX2,SLC4A4,MAML2,RYR3,QKI,CTNND2,AHCYL2,NPAS3,ERBB4,CADM1,NRXN1,PARD3B
2.341e-06	-12.96	autonomic_ganglia	COSMIC cancer mutations	autonomic_ganglia	4005	27	16828	49	RFX4,NCKAP5,FGFR3,ATP1A2,ACSS1,SLC1A2,CTNND2,NPAS3,ERBB4,PARD3B,PREX2,SLC4A4,NHSL1,RYR3,MAML2,GPM6A,PCDH9,MACF1,COL5A3,PITPNC1,ZNF98,NFIA,TRPS1,PTPRZ1,TNIK,HIF3A,FBXL7
2.521e-06	-12.89	multicellular organism development	biological process	GO:0007275	3957	26	18204	50	NRXN1,SLC1A2,CTNNA2,FGFR3,HIF3A,PTPRZ1,RORA,ERBB4,TRPS1,PCDH9,NTM,PREX2,RFX4,LRIG1,TNIK,CTNND2,GPM6A,ATP1A2,CADM1,CDH20,MSI2,SOX5,SLC1A3,NFIA,LSAMP,QKI
3.516e-06	-12.56	tibia	COSMIC cancer mutations	tibia	836	12	16828	49	FGFR3,LSAMP,MACF1,NCKAP5,ABLIM1,GPM6A,ACSS1,NKAIN3,CTNND2,QKI,PREX2,TNIK
3.596e-06	-12.54	intestinal_adenocarcinoma	COSMIC cancer mutations	intestinal_adenocarcinoma	7225	37	16828	49	PCDH9,MACF1,ITPR2,LSAMP,RORA,SFXN5,COL5A3,CDH20,PITPNC1,ZNF98,NFIA,TRPS1,PTPRZ1,SOX5,FBXL7,NCKAP5,ATP13A4,FGFR3,RFX4,CST3,NTM,LRIG1,ACSS1,ATP1A2,ZBTB20,PARD3B,NRXN1,SLC1A2,CTNND2,QKI,ERBB4,NPAS3,SLC4A4,NHSL1,RYR3,MAML2,PREX2
3.596e-06	-12.54	stomach-carcinoma-intestinal_adenocarcinoma	COSMIC cancer mutations	stomach-carcinoma-intestinal_adenocarcinoma	7225	37	16828	49	PITPNC1,ZNF98,TRPS1,NFIA,PTPRZ1,CDH20,SOX5,FBXL7,RORA,MACF1,PCDH9,ITPR2,LSAMP,COL5A3,SFXN5,SLC1A2,QKI,CTNND2,ERBB4,NPAS3,PARD3B,NRXN1,PREX2,NHSL1,SLC4A4,RYR3,MAML2,RFX4,CST3,NCKAP5,ATP13A4,FGFR3,ATP1A2,ZBTB20,NTM,ACSS1,LRIG1
4.679e-06	-12.27	cell junction	cellular component	GO:0030054	2224	18	19108	49	PARD3B,QKI,CDH20,ATP1A2,PTPRZ1,CTNNA2,CTNND2,GPM6A,DTNA,CADM1,ERBB4,NFIA,NRXN1,TNIK,SLC1A3,PCDH9,FGFR3,SLC1A2
6.215e-06	-11.99	upper_aerodigestive_tract	COSMIC cancer mutations	upper_aerodigestive_tract	13181	49	16828	49	RYR3,SLC4A4,NHSL1,CADM1,ZBTB20,DTNA,SLC1A3,ATP1A2,LRIG1,NTM,TNIK,FBXL7,HIF3A,NFIA,PTPRZ1,PITPNC1,ZNF98,CDH20,GPM6A,PCDH9,MACF1,ITPR2,LSAMP,PREX2,MAML2,ERBB4,NPAS3,SLC1A2,QKI,AHCYL2,CTNND2,NRXN1,PARD3B,ACSS1,CST3,MSI2,RFX4,ATP13A4,FGFR3,NCKAP5,SOX5,TRPS1,NKAIN3,COL5A3,GPC5,SFXN5,RORA,PTGDS,ABLIM1
7.624e-06	-11.78	upper_aerodigestive_tract-pharynx-carcinoma-nasopharyngeal_carcinoma	COSMIC cancer mutations	upper_aerodigestive_tract-pharynx-carcinoma-nasopharyngeal_carcinoma	1425	15	16828	49	PREX2,NHSL1,SLC4A4,NFIA,PITPNC1,SLC1A2,CTNND2,ZNF98,QKI,ATP1A2,SFXN5,RFX4,ATP13A4,FGFR3,NCKAP5
7.624e-06	-11.78	nasopharyngeal_carcinoma	COSMIC cancer mutations	nasopharyngeal_carcinoma	1425	15	16828	49	NFIA,SLC1A2,PITPNC1,ZNF98,QKI,CTNND2,SLC4A4,NHSL1,PREX2,ATP13A4,FGFR3,NCKAP5,RFX4,SFXN5,ATP1A2
7.657e-06	-11.78	autonomic_ganglia-neuroblastoma	COSMIC cancer mutations	autonomic_ganglia-neuroblastoma	3970	26	16828	49	PARD3B,SLC1A2,CTNND2,NPAS3,ERBB4,SLC4A4,MAML2,RYR3,PREX2,NCKAP5,FGFR3,RFX4,ACSS1,ATP1A2,PITPNC1,ZNF98,NFIA,TRPS1,PTPRZ1,HIF3A,FBXL7,TNIK,MACF1,PCDH9,GPM6A,COL5A3
7.694e-06	-11.78	neuroblastoma	COSMIC cancer mutations	neuroblastoma	3971	26	16828	49	PARD3B,CTNND2,SLC1A2,ERBB4,NPAS3,SLC4A4,RYR3,MAML2,PREX2,NCKAP5,FGFR3,RFX4,ACSS1,ATP1A2,ZNF98,PITPNC1,PTPRZ1,NFIA,TRPS1,HIF3A,FBXL7,TNIK,PCDH9,MACF1,GPM6A,COL5A3
9.205e-06	-11.60	neurogenesis	biological process	GO:0022008	1334	14	18204	50	NRXN1,CTNND2,CTNNA2,PTPRZ1,GPM6A,RORA,ERBB4,SOX5,SLC1A3,NTM,PREX2,NFIA,QKI,TNIK
9.407e-06	-11.57	bone-tibia-other-chondroblastoma	COSMIC cancer mutations	bone-tibia-other-chondroblastoma	98	5	16828	49	CTNND2,GPM6A,NKAIN3,NCKAP5,LSAMP
1.006e-05	-11.51	plasma membrane	cellular component	GO:0005886	5538	29	19108	49	PREX2,ATP1A2,CDH20,LRIG1,CST3,TNIK,SLC1A3,MACF1,GPC5,ERBB4,CADM1,NKAIN3,SLC4A4,CTNNA2,PTPRZ1,ITPR2,ATP13A4,PARD3B,SLC1A2,FGFR3,NTM,HIF3A,PCDH9,NRXN1,GPM6A,DTNA,LSAMP,CTNND2,RYR3
1.014e-05	-11.50	generation of neurons	biological process	GO:0048699	1158	13	18204	50	RORA,ERBB4,CTNNA2,GPM6A,PTPRZ1,NRXN1,CTNND2,TNIK,NFIA,PREX2,SOX5,SLC1A3,NTM
1.294e-05	-11.26	anatomical structure morphogenesis	biological process	GO:0009653	2225	18	18204	50	QKI,NFIA,LRIG1,TNIK,SLC1A3,ABLIM1,SOX5,PREX2,ERBB4,RORA,CDH20,CTNND2,NRXN1,HIF3A,GPM6A,PTPRZ1,CTNNA2,FGFR3
1.332e-05	-11.23	scalp	COSMIC cancer mutations	scalp	2110	18	16828	49	SOX5,SLC4A4,PREX2,NRXN1,CADM1,PTPRZ1,ERBB4,NFIA,TRPS1,GPC5,NTM,COL5A3,ATP1A2,FGFR3,ATP13A4,LSAMP,MACF1,RORA
1.437e-05	-11.15	cell morphogenesis	biological process	GO:0000902	687	10	18204	50	SLC1A3,CTNND2,NRXN1,GPM6A,PTPRZ1,CTNNA2,PREX2,NFIA,CDH20,TNIK
1.661e-05	-11.01	PDZD2 (PDZ domain containing 2)	protein interactions	23037	20	3	19454	49	CTNND2,NRXN1,CST3
1.707e-05	-10.98	cell periphery	cellular component	GO:0071944	6020	30	19108	49	CTNNA2,PTPRZ1,ITPR2,PARD3B,ATP13A4,HIF3A,PCDH9,SLC1A2,FGFR3,NTM,NRXN1,CTNND2,LSAMP,DTNA,GPM6A,RYR3,PREX2,ATP1A2,CDH20,TNIK,MACF1,SLC1A3,LRIG1,CST3,CADM1,GPC5,ERBB4,COL5A3,SLC4A4,NKAIN3
2.407e-05	-10.63	humerus	COSMIC cancer mutations	humerus	546	9	16828	49	NKAIN3,GPC5,HIF3A,SOX5,SFXN5,GPM6A,AHCYL2,PARD3B,NCKAP5
2.465e-05	-10.61	bone-humerus-other-chondroblastoma	COSMIC cancer mutations	bone-humerus-other-chondroblastoma	301	7	16828	49	GPC5,SFXN5,SOX5,NKAIN3,NCKAP5,GPM6A,AHCYL2
2.586e-05	-10.56	carcinoid-endocrine_tumour	COSMIC cancer mutations	carcinoid-endocrine_tumour	7752	37	16828	49	GPM6A,RORA,PCDH9,ABLIM1,MACF1,LSAMP,ITPR2,COL5A3,NKAIN3,SFXN5,GPC5,ZNF98,TRPS1,PTPRZ1,CDH20,TNIK,SOX5,FBXL7,RFX4,NCKAP5,ATP13A4,FGFR3,SLC1A3,ATP1A2,ACSS1,LRIG1,SLC1A2,CTNND2,AHCYL2,QKI,ERBB4,CADM1,PREX2,NHSL1,SLC4A4,MAML2,RYR3
2.682e-05	-10.53	neuron differentiation	biological process	GO:0030182	1081	12	18204	50	CTNNA2,PREX2,GPM6A,PTPRZ1,NRXN1,SLC1A3,CTNND2,NTM,TNIK,NFIA,RORA,ERBB4
2.973e-05	-10.42	lymphoid_neoplasm	COSMIC cancer mutations	lymphoid_neoplasm	12233	47	16828	49	RORA,ABLIM1,COL5A3,NKAIN3,SFXN5,GPC5,TRPS1,SOX5,RFX4,MSI2,NCKAP5,ATP13A4,FGFR3,ACSS1,SLC1A2,CTNND2,AHCYL2,QKI,NPAS3,ERBB4,NRXN1,PARD3B,PREX2,MAML2,GPM6A,PCDH9,MACF1,LSAMP,ITPR2,PITPNC1,ZNF98,NFIA,PTPRZ1,CDH20,TNIK,HIF3A,FBXL7,SLC1A3,ATP1A2,DTNA,ZBTB20,NTM,LRIG1,CADM1,NHSL1,SLC4A4,RYR3
4.464e-05	-10.02	anatomical structure development	biological process	GO:0048856	5207	28	18204	50	PREX2,RFX4,ABLIM1,NTM,TNIK,LRIG1,FGFR3,CTNNA2,PTPRZ1,HIF3A,NRXN1,SLC1A2,TRPS1,PCDH9,RORA,ERBB4,MSI2,SOX5,SLC1A3,NFIA,QKI,LSAMP,GPM6A,ATP1A2,COL5A3,CTNND2,CADM1,CDH20
4.501e-05	-10.01	multicellular organismal process	biological process	GO:0032501	6177	31	18204	50	PCDH9,TRPS1,PTGDS,ERBB4,RORA,HIF3A,PTPRZ1,CTNNA2,FGFR3,SLC1A2,NRXN1,TNIK,SLC4A4,RYR3,LRIG1,RFX4,PREX2,NTM,ABLIM1,DTNA,CDH20,CADM1,ATP1A2,GPM6A,CTNND2,LSAMP,QKI,NFIA,SLC1A3,MSI2,SOX5
4.627e-05	-9.98	Ig_3	pfam domains	PF13927	141	5	17795	50	LRIG1,CADM1,LSAMP,FGFR3,NTM
4.917e-05	-9.92	Neurotransmitter uptake and Metabolism In Glial Cells	REACTOME pathways	R-HSA-112313	4	2	10285	30	SLC1A3,SLC1A2
4.917e-05	-9.92	Astrocytic Glutamate-Glutamine Uptake And Metabolism	REACTOME pathways	R-HSA-210455	4	2	10285	30	SLC1A2,SLC1A3
6.571e-05	-9.63	high-affinity L-glutamate transmembrane transporter activity	molecular function	GO:0005314	5	2	18094	47	SLC1A2,SLC1A3
6.571e-05	-9.63	glutamate:sodium symporter activity	molecular function	GO:0015501	5	2	18094	47	SLC1A2,SLC1A3
7.355e-05	-9.52	D-aspartate transmembrane transport	biological process	GO:0070777	5	2	18204	50	SLC1A3,SLC1A2
7.355e-05	-9.52	D-aspartate import across plasma membrane	biological process	GO:0070779	5	2	18204	50	SLC1A2,SLC1A3
7.513e-05	-9.50	neurotransmitter uptake	biological process	GO:0001504	30	3	18204	50	ATP1A2,SLC1A3,SLC1A2
7.769e-05	-9.46	NTM (neurotrimin)	protein interactions	50863	33	3	19454	49	NTM,LSAMP,GPM6A
8.981e-05	-9.32	developmental process	biological process	GO:0032502	5716	29	18204	50	TNIK,LRIG1,RFX4,PREX2,NTM,ABLIM1,PCDH9,TRPS1,ERBB4,RORA,HIF3A,PTPRZ1,CTNNA2,FGFR3,SLC1A2,NRXN1,LSAMP,QKI,NFIA,NHSL1,SLC1A3,SOX5,MSI2,CADM1,CDH20,GPM6A,ATP1A2,CTNND2,COL5A3
9.059e-05	-9.31	transport across blood-brain barrier	biological process	GO:0150104	86	4	18204	50	ATP1A2,SLC1A3,SLC4A4,SLC1A2
9.059e-05	-9.31	vascular transport	biological process	GO:0010232	86	4	18204	50	ATP1A2,SLC4A4,SLC1A3,SLC1A2
1.004e-04	-9.21	response to auditory stimulus	biological process	GO:0010996	33	3	18204	50	SLC1A3,NRXN1,ATP1A2
1.045e-04	-9.17	MAPT (microtubule associated protein tau)	protein interactions	4137	948	10	19454	49	GPM6A,ABLIM1,CTNND2,SLC1A2,ATP1A2,SLC1A3,TNIK,NTM,LSAMP,CTNNA2
1.064e-04	-9.15	RIH_assoc-dom	interpro domains	IPR013662	6	2	18521	50	ITPR2,RYR3
1.064e-04	-9.15	Ins145_P3_rcpt	interpro domains	IPR014821	6	2	18521	50	RYR3,ITPR2
1.064e-04	-9.15	Ryanodine_IP3_receptor	interpro domains	IPR015925	6	2	18521	50	RYR3,ITPR2
1.064e-04	-9.15	RIH_dom	interpro domains	IPR000699	6	2	18521	50	RYR3,ITPR2
1.064e-04	-9.15	RyR/IP3R_RIH_dom_sf	interpro domains	IPR035910	6	2	18521	50	ITPR2,RYR3
1.101e-04	-9.11	D-amino acid transport	biological process	GO:0042940	6	2	18204	50	SLC1A2,SLC1A3
1.101e-04	-9.11	L-aspartate import across plasma membrane	biological process	GO:0140009	6	2	18204	50	SLC1A3,SLC1A2
1.152e-04	-9.07	RYDR_ITPR	pfam domains	PF01365	6	2	17795	50	RYR3,ITPR2
1.152e-04	-9.07	Ins145_P3_rec	pfam domains	PF08709	6	2	17795	50	ITPR2,RYR3
1.152e-04	-9.07	RIH_assoc	pfam domains	PF08454	6	2	17795	50	RYR3,ITPR2
1.162e-04	-9.06	monoatomic ion transmembrane transporter activity	molecular function	GO:0015075	752	9	18094	47	RYR3,GPM6A,ITPR2,SLC1A2,SLC4A4,SFXN5,SLC1A3,ATP13A4,ATP1A2
1.186e-04	-9.04	Salivary secretion	KEGG pathways	ko04970	90	4	7161	21	CST3,ATP1A2,ITPR2,RYR3
1.186e-04	-9.04	Salivary secretion	KEGG pathways	hsa04970	90	4	7161	21	RYR3,ITPR2,ATP1A2,CST3
1.255e-04	-8.98	skin-scalp-carcinoma-squamous_cell_carcinoma	COSMIC cancer mutations	skin-scalp-carcinoma-squamous_cell_carcinoma	1596	14	16828	49	SLC4A4,SOX5,TRPS1,PTPRZ1,NRXN1,CADM1,ATP1A2,COL5A3,GPC5,RORA,ATP13A4,FGFR3,MACF1,LSAMP
1.284e-04	-8.96	IP3 receptor type 1 binding core, RIH domain	gene3d domains	1.25.10.30	6	2	14470	43	RYR3,ITPR2
1.338e-04	-8.92	metal ion transmembrane transporter activity	molecular function	GO:0046873	442	7	18094	47	SLC1A3,ATP1A2,SLC1A2,SLC4A4,ITPR2,GPM6A,RYR3
1.487e-04	-8.81	Na-dicarboxylate_symporter	interpro domains	IPR001991	7	2	18521	50	SLC1A3,SLC1A2
1.487e-04	-8.81	Na:dicarbo_symporter_sf	interpro domains	IPR036458	7	2	18521	50	SLC1A2,SLC1A3
1.487e-04	-8.81	Na-dicarboxylate_symporter_CS	interpro domains	IPR018107	7	2	18521	50	SLC1A2,SLC1A3
1.582e-04	-8.75	CASK (calcium/calmodulin dependent serine protein kinase)	protein interactions	8573	204	5	19454	49	ABLIM1,NRXN1,CADM1,DTNA,PARD3B
1.585e-04	-8.75	CTNNA1 (catenin alpha 1)	protein interactions	1495	325	6	19454	49	TNIK,DTNA,NHSL1,CTNNA2,MACF1,ABLIM1
1.610e-04	-8.73	SDF	pfam domains	PF00375	7	2	17795	50	SLC1A3,SLC1A2
1.662e-04	-8.70	cellular response to alkaloid	biological process	GO:0071312	39	3	18204	50	RYR3,SLC1A2,SLC1A3
1.695e-04	-8.68	beta-catenin binding	molecular function	GO:0008013	107	4	18094	47	CTNND2,RORA,CDH20,CTNNA2
1.762e-04	-8.64	pancreas-carcinoid-endocrine_tumour	COSMIC cancer mutations	pancreas-carcinoid-endocrine_tumour	7250	34	16828	49	COL5A3,NKAIN3,SFXN5,GPC5,GPM6A,RORA,ITPR2,LSAMP,ABLIM1,PCDH9,MACF1,SOX5,FBXL7,ZNF98,CDH20,ATP1A2,SLC1A3,ACSS1,LRIG1,RFX4,NCKAP5,FGFR3,ATP13A4,PREX2,NHSL1,SLC4A4,RYR3,MAML2,AHCYL2,CTNND2,QKI,SLC1A2,ERBB4,CADM1
1.794e-04	-8.63	Sodium:dicarboxylate symporter	gene3d domains	1.10.3860.10	7	2	14470	43	SLC1A3,SLC1A2
1.955e-04	-8.54	monoatomic cation transmembrane transporter activity	molecular function	GO:0008324	630	8	18094	47	RYR3,GPM6A,SLC1A3,ATP1A2,ATP13A4,ITPR2,SLC4A4,SLC1A2
2.037e-04	-8.50	cell adhesion	biological process	GO:0007155	942	10	18204	50	NRXN1,NTM,COL5A3,PARD3B,CTNND2,CTNNA2,LSAMP,CDH20,CADM1,PCDH9
2.071e-04	-8.48	right_upper_lobe	COSMIC cancer mutations	right_upper_lobe	10376	42	16828	49	RFX4,ATP13A4,FGFR3,NCKAP5,ZBTB20,SLC1A3,DTNA,ATP1A2,LRIG1,NTM,NPAS3,ERBB4,SLC1A2,CTNND2,AHCYL2,NRXN1,PARD3B,CADM1,PREX2,RYR3,SLC4A4,GPM6A,RORA,MACF1,ABLIM1,PCDH9,LSAMP,ITPR2,NKAIN3,COL5A3,GPC5,SFXN5,NFIA,TRPS1,PTPRZ1,PITPNC1,ZNF98,CDH20,TNIK,FBXL7,HIF3A,SOX5
2.071e-04	-8.48	lung-right_upper_lobe-carcinoma-adenocarcinoma	COSMIC cancer mutations	lung-right_upper_lobe-carcinoma-adenocarcinoma	10376	42	16828	49	PREX2,RYR3,SLC4A4,NPAS3,ERBB4,SLC1A2,CTNND2,AHCYL2,NRXN1,PARD3B,CADM1,ZBTB20,DTNA,SLC1A3,ATP1A2,LRIG1,NTM,RFX4,ATP13A4,FGFR3,NCKAP5,TNIK,FBXL7,SOX5,HIF3A,NFIA,TRPS1,PTPRZ1,PITPNC1,ZNF98,CDH20,NKAIN3,COL5A3,GPC5,SFXN5,GPM6A,RORA,MACF1,ABLIM1,PCDH9,ITPR2,LSAMP
2.212e-04	-8.42	LSAMP (limbic system associated membrane protein)	protein interactions	4045	9	2	19454	49	LSAMP,NTM
2.212e-04	-8.42	NEGR1 (neuronal growth regulator 1)	protein interactions	257194	9	2	19454	49	LSAMP,NTM
2.300e-04	-8.38	cervix-carcinoma-squamous_cell_carcinoma	COSMIC cancer mutations	cervix-carcinoma-squamous_cell_carcinoma	11789	45	16828	49	CDH20,NFIA,PTPRZ1,PITPNC1,ZNF98,FBXL7,HIF3A,TNIK,MACF1,PCDH9,LSAMP,ITPR2,GPM6A,CADM1,RYR3,NHSL1,SLC4A4,LRIG1,NTM,ZBTB20,SLC1A3,DTNA,ATP1A2,TRPS1,SOX5,ABLIM1,RORA,GPC5,SFXN5,COL5A3,PARD3B,NRXN1,ERBB4,NPAS3,SLC1A2,CTNND2,QKI,MAML2,PREX2,ATP13A4,FGFR3,NCKAP5,CST3,RFX4,ACSS1
2.328e-04	-8.37	cervix	COSMIC cancer mutations	cervix	11793	45	16828	49	CST3,RFX4,FGFR3,ATP13A4,NCKAP5,ACSS1,ERBB4,NPAS3,CTNND2,QKI,SLC1A2,PARD3B,NRXN1,PREX2,MAML2,RORA,ABLIM1,COL5A3,GPC5,SFXN5,TRPS1,SOX5,ZBTB20,SLC1A3,DTNA,ATP1A2,LRIG1,NTM,CADM1,RYR3,SLC4A4,NHSL1,GPM6A,ITPR2,LSAMP,MACF1,PCDH9,PTPRZ1,NFIA,ZNF98,PITPNC1,CDH20,TNIK,FBXL7,HIF3A
2.329e-04	-8.37	EDTRNSPORT	prints domains	PR00173	7	2	5227	18	SLC1A3,SLC1A2
2.383e-04	-8.34	right_lower_lobe	COSMIC cancer mutations	right_lower_lobe	5692	29	16828	49	CST3,NCKAP5,ATP13A4,ATP1A2,SLC1A3,DTNA,NTM,LRIG1,CTNND2,AHCYL2,NPAS3,ERBB4,PARD3B,SLC4A4,RYR3,MAML2,GPM6A,MACF1,ITPR2,LSAMP,COL5A3,NKAIN3,GPC5,ZNF98,TRPS1,PTPRZ1,CDH20,SOX5,FBXL7
2.383e-04	-8.34	lung-right_lower_lobe-carcinoma-adenocarcinoma	COSMIC cancer mutations	lung-right_lower_lobe-carcinoma-adenocarcinoma	5692	29	16828	49	CST3,NCKAP5,ATP13A4,DTNA,ATP1A2,SLC1A3,NTM,LRIG1,CTNND2,AHCYL2,NPAS3,ERBB4,PARD3B,SLC4A4,MAML2,RYR3,GPM6A,MACF1,LSAMP,ITPR2,COL5A3,NKAIN3,GPC5,ZNF98,TRPS1,PTPRZ1,CDH20,SOX5,FBXL7
2.409e-04	-8.33	NA_DICARBOXYL_SYMP_2	prosite domains	PS00714	7	2	12186	42	SLC1A3,SLC1A2
2.409e-04	-8.33	NA_DICARBOXYL_SYMP_1	prosite domains	PS00713	7	2	12186	42	SLC1A2,SLC1A3
2.464e-04	-8.31	Transport of inorganic cations/anions and amino acids/oligopeptides	REACTOME pathways	R-HSA-425393	107	4	10285	30	SLC4A4,SLC1A2,AHCYL2,SLC1A3
2.655e-04	-8.23	synapse	cellular component	GO:0045202	1473	12	19108	49	CTNND2,GPM6A,DTNA,SLC1A3,TNIK,SLC1A2,CADM1,ERBB4,NRXN1,ATP1A2,QKI,PTPRZ1
2.909e-04	-8.14	nodular	COSMIC cancer mutations	nodular	1515	13	16828	49	ATP1A2,ABLIM1,MACF1,ATP13A4,FGFR3,SLC4A4,HIF3A,PREX2,CDH20,CTNND2,NPAS3,ERBB4,PTPRZ1
3.003e-04	-8.11	monoatomic ion transmembrane transport	biological process	GO:0034220	804	9	18204	50	ITPR2,RYR3,SLC4A4,ATP13A4,ATP1A2,GPM6A,SFXN5,SLC1A2,SLC1A3
3.121e-04	-8.07	cell-cell junction	cellular component	GO:0005911	513	7	19108	49	CTNNA2,PCDH9,CADM1,ATP1A2,CTNND2,CDH20,PARD3B
3.155e-04	-8.06	plasma membrane region	cellular component	GO:0098590	1278	11	19108	49	GPM6A,ATP1A2,PARD3B,SLC4A4,SLC1A2,SLC1A3,MACF1,TNIK,ERBB4,NRXN1,CADM1
3.155e-04	-8.06	Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour	COSMIC cancer mutations	Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour	7434	34	16828	49	FGFR3,ATP13A4,NCKAP5,CST3,LRIG1,ACSS1,ZBTB20,DTNA,SLC1A3,ATP1A2,NRXN1,PARD3B,CADM1,ERBB4,NPAS3,QKI,CTNND2,RYR3,MAML2,SLC4A4,PREX2,PTGDS,ITPR2,MACF1,ABLIM1,RORA,NKAIN3,COL5A3,PTPRZ1,TRPS1,ZNF98,SOX5,HIF3A,TNIK
3.165e-04	-8.06	central nervous system development	biological process	GO:0007417	995	10	18204	50	RORA,QKI,ERBB4,PCDH9,MSI2,SLC1A2,CTNNA2,ATP1A2,RFX4,PTPRZ1
3.170e-04	-8.06	MIR_dom_sf	interpro domains	IPR036300	10	2	18521	50	RYR3,ITPR2
3.170e-04	-8.06	MIR_motif	interpro domains	IPR016093	10	2	18521	50	ITPR2,RYR3
3.234e-04	-8.04	upper_aerodigestive_tract-mouth-carcinoma	COSMIC cancer mutations	upper_aerodigestive_tract-mouth-carcinoma	6426	31	16828	49	HIF3A,SOX5,FBXL7,PITPNC1,TRPS1,CDH20,COL5A3,SFXN5,GPC5,GPM6A,RORA,MACF1,ABLIM1,PREX2,SLC4A4,NHSL1,RYR3,MAML2,SLC1A2,CTNND2,QKI,ERBB4,NPAS3,PARD3B,SLC1A3,ZBTB20,NTM,ACSS1,RFX4,NCKAP5,FGFR3
3.281e-04	-8.02	cellular response to cocaine	biological process	GO:0071314	10	2	18204	50	SLC1A2,SLC1A3
3.346e-04	-8.00	central_nervous_system-brainstem-glioma-oligoastrocytoma_Grade_III	COSMIC cancer mutations	central_nervous_system-brainstem-glioma-oligoastrocytoma_Grade_III	114	4	16828	49	PREX2,SLC1A2,RYR3,SOX5
3.424e-04	-7.98	neuron projection morphogenesis	biological process	GO:0048812	486	7	18204	50	PTPRZ1,GPM6A,CTNNA2,PREX2,CTNND2,NRXN1,TNIK
3.432e-04	-7.98	MIR	pfam domains	PF02815	10	2	17795	50	RYR3,ITPR2
3.642e-04	-7.92	plasma membrane bounded cell projection morphogenesis	biological process	GO:0120039	491	7	18204	50	PTPRZ1,GPM6A,CTNNA2,PREX2,CTNND2,NRXN1,TNIK
3.648e-04	-7.92	Bicarbonate transporters	REACTOME pathways	R-HSA-425381	10	2	10285	30	AHCYL2,SLC4A4
3.870e-04	-7.86	cell projection morphogenesis	biological process	GO:0048858	496	7	18204	50	PTPRZ1,GPM6A,CTNNA2,PREX2,CTNND2,NRXN1,TNIK
3.975e-04	-7.83	NAKATPASE	prints domains	PR00121	9	2	5227	18	ATP13A4,ATP1A2
4.003e-04	-7.82	L-glutamate import across plasma membrane	biological process	GO:0098712	11	2	18204	50	SLC1A3,SLC1A2
4.003e-04	-7.82	L-aspartate transmembrane transport	biological process	GO:0070778	11	2	18204	50	SLC1A2,SLC1A3
4.404e-04	-7.73	Ig_I-set	interpro domains	IPR013098	132	4	18521	50	NTM,LSAMP,LRIG1,FGFR3
4.439e-04	-7.72	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-follicular_lymphoma	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-follicular_lymphoma	981	10	16828	49	NCKAP5,PCDH9,LSAMP,ITPR2,RORA,CTNND2,ZNF98,GPC5,SOX5,NKAIN3
4.529e-04	-7.70	Ig_sub2	interpro domains	IPR003598	239	5	18521	50	LSAMP,LRIG1,NTM,FGFR3,CADM1
4.593e-04	-7.69	haematopoietic_neoplasm	COSMIC cancer mutations	haematopoietic_neoplasm	11082	43	16828	49	RFX4,MSI2,NCKAP5,FGFR3,ATP13A4,DTNA,ATP1A2,SLC1A3,NTM,ACSS1,LRIG1,AHCYL2,QKI,CTNND2,SLC1A2,ERBB4,NPAS3,CADM1,PARD3B,NRXN1,PREX2,SLC4A4,NHSL1,MAML2,RYR3,RORA,LSAMP,ITPR2,PCDH9,ABLIM1,MACF1,COL5A3,NKAIN3,SFXN5,GPC5,ZNF98,PTPRZ1,NFIA,CDH20,TNIK,HIF3A,SOX5,FBXL7
4.781e-04	-7.65	stomach-adenocarcinoma	COSMIC cancer mutations	stomach-adenocarcinoma	4101	23	16828	49	CDH20,TRPS1,ITPR2,ABLIM1,PCDH9,MACF1,RORA,GPC5,COL5A3,PARD3B,ERBB4,CTNND2,QKI,AHCYL2,SLC1A2,SLC4A4,PREX2,FGFR3,ATP13A4,RFX4,LRIG1,ACSS1,ATP1A2
4.795e-04	-7.64	auditory behavior	biological process	GO:0031223	12	2	18204	50	NRXN1,SLC1A3
4.874e-04	-7.63	neuron development	biological process	GO:0048666	859	9	18204	50	PREX2,CTNNA2,GPM6A,PTPRZ1,NRXN1,CTNND2,SLC1A3,NTM,TNIK
4.895e-04	-7.62	trunk	COSMIC cancer mutations	trunk	3554	21	16828	49	ATP1A2,SLC1A3,LSAMP,PCDH9,NCKAP5,ABLIM1,MACF1,FGFR3,ATP13A4,HIF3A,SOX5,MAML2,RYR3,PREX2,NRXN1,CDH20,CTNND2,NPAS3,PTPRZ1,ERBB4,TRPS1
5.115e-04	-7.58	I-set	pfam domains	PF07679	132	4	17795	50	NTM,FGFR3,LSAMP,LRIG1
5.128e-04	-7.58	MIR	prosite domains	PS50919	10	2	12186	42	ITPR2,RYR3
5.247e-04	-7.55	thyroid-carcinoma	COSMIC cancer mutations	thyroid-carcinoma	4126	23	16828	49	COL5A3,GPC5,MACF1,PCDH9,ITPR2,LSAMP,TNIK,SOX5,HIF3A,NFIA,TRPS1,PTPRZ1,DTNA,ATP1A2,ACSS1,LRIG1,ATP13A4,FGFR3,RYR3,CTNND2,ERBB4,CADM1,NRXN1
5.566e-04	-7.49	ovary-carcinoma-serous_carcinoma	COSMIC cancer mutations	ovary-carcinoma-serous_carcinoma	10710	42	16828	49	NCKAP5,ATP13A4,FGFR3,CST3,MSI2,NTM,ACSS1,LRIG1,ATP1A2,DTNA,SLC1A3,ZBTB20,CADM1,PARD3B,NRXN1,SLC1A2,CTNND2,AHCYL2,QKI,ERBB4,NPAS3,SLC4A4,NHSL1,MAML2,RYR3,PREX2,MACF1,PCDH9,ITPR2,LSAMP,PTGDS,RORA,SFXN5,GPC5,COL5A3,CDH20,ZNF98,TRPS1,PTPRZ1,SOX5,FBXL7,TNIK
5.593e-04	-7.49	Ion homeostasis	REACTOME pathways	R-HSA-5578775	56	3	10285	30	ATP1A2,RYR3,ITPR2
5.625e-04	-7.48	cell adhesion molecule binding	molecular function	GO:0050839	560	7	18094	47	CTNNA2,CADM1,MACF1,CDH20,NRXN1,CTNND2,PTPRZ1
5.787e-04	-7.45	follicular_lymphoma	COSMIC cancer mutations	follicular_lymphoma	1209	11	16828	49	TNIK,SOX5,CTNND2,ZNF98,NKAIN3,GPC5,RORA,NCKAP5,PCDH9,LSAMP,ITPR2
5.865e-04	-7.44	neurotransmitter transport	biological process	GO:0006836	140	4	18204	50	ATP1A2,NRXN1,SLC1A2,SLC1A3
5.891e-04	-7.44	L-glutamate transmembrane transporter activity	molecular function	GO:0005313	14	2	18094	47	SLC1A3,SLC1A2
6.143e-04	-7.40	biliary_tract-gallbladder-carcinoma-adenocarcinoma	COSMIC cancer mutations	biliary_tract-gallbladder-carcinoma-adenocarcinoma	2821	18	16828	49	ITPR2,PCDH9,MACF1,FGFR3,COL5A3,NKAIN3,LRIG1,CTNND2,ZNF98,PITPNC1,ERBB4,PTPRZ1,TRPS1,TNIK,PREX2,NHSL1,SLC4A4,RYR3
6.143e-04	-7.40	gallbladder	COSMIC cancer mutations	gallbladder	2821	18	16828	49	FGFR3,PCDH9,MACF1,ITPR2,NKAIN3,COL5A3,LRIG1,TRPS1,ERBB4,PTPRZ1,PITPNC1,ZNF98,CTNND2,TNIK,PREX2,RYR3,NHSL1,SLC4A4
6.144e-04	-7.39	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm	7307	33	16828	49	PCDH9,ABLIM1,MACF1,ITPR2,LSAMP,RORA,GPM6A,GPC5,SFXN5,NKAIN3,COL5A3,CDH20,PTPRZ1,FBXL7,SOX5,TNIK,ATP13A4,NCKAP5,RFX4,ACSS1,LRIG1,SLC1A3,PARD3B,CADM1,ERBB4,SLC1A2,AHCYL2,QKI,CTNND2,RYR3,MAML2,NHSL1,PREX2
6.228e-04	-7.38	MIR	smart domains	SM00472	10	2	9717	37	RYR3,ITPR2
6.366e-04	-7.36	Neurexin-like	interpro domains	IPR003585	14	2	18521	50	CADM1,NRXN1
6.588e-04	-7.33	mechanosensory behavior	biological process	GO:0007638	14	2	18204	50	NRXN1,SLC1A3
6.588e-04	-7.33	sodium ion export across plasma membrane	biological process	GO:0036376	14	2	18204	50	SLC4A4,ATP1A2
6.866e-04	-7.28	adult behavior	biological process	GO:0030534	146	4	18204	50	ATP1A2,PREX2,SLC1A2,NRXN1
7.003e-04	-7.26	active monoatomic ion transmembrane transporter activity	molecular function	GO:0022853	274	5	18094	47	ATP1A2,SLC1A3,ATP13A4,SLC4A4,SLC1A2
7.220e-04	-7.23	dendrite morphogenesis	biological process	GO:0048813	64	3	18204	50	CTNNA2,PREX2,CTNND2
7.454e-04	-7.20	sodium ion transmembrane transporter activity	molecular function	GO:0015081	158	4	18094	47	ATP1A2,SLC1A3,SLC1A2,SLC4A4
7.502e-04	-7.20	haematopoietic_and_lymphoid_tissue-haematopoietic_neoplasm-mast_cell_neoplasm	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue-haematopoietic_neoplasm-mast_cell_neoplasm	248	5	16828	49	NFIA,NPAS3,ERBB4,PCDH9,GPC5
7.502e-04	-7.20	mast_cell_neoplasm	COSMIC cancer mutations	mast_cell_neoplasm	248	5	16828	49	GPC5,PCDH9,NFIA,ERBB4,NPAS3
7.583e-04	-7.18	inorganic cation transmembrane transporter activity	molecular function	GO:0022890	589	7	18094	47	SLC1A3,ATP1A2,ITPR2,SLC1A2,SLC4A4,RYR3,GPM6A
8.065e-04	-7.12	acute_myeloid_leukaemia	COSMIC cancer mutations	acute_myeloid_leukaemia	10418	41	16828	49	SFXN5,GPC5,COL5A3,NKAIN3,LSAMP,ITPR2,MACF1,PCDH9,ABLIM1,RORA,SOX5,HIF3A,FBXL7,TNIK,CDH20,ZNF98,PTPRZ1,NFIA,NTM,ACSS1,LRIG1,SLC1A3,ATP1A2,NCKAP5,ATP13A4,RFX4,MSI2,SLC4A4,NHSL1,RYR3,MAML2,PREX2,CADM1,PARD3B,NRXN1,AHCYL2,QKI,CTNND2,SLC1A2,NPAS3,ERBB4
8.065e-04	-7.12	haematopoietic_and_lymphoid_tissue-haematopoietic_neoplasm-acute_myeloid_leukaemia	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue-haematopoietic_neoplasm-acute_myeloid_leukaemia	10418	41	16828	49	CDH20,ZNF98,PTPRZ1,NFIA,HIF3A,SOX5,FBXL7,TNIK,ITPR2,LSAMP,MACF1,PCDH9,ABLIM1,RORA,SFXN5,GPC5,COL5A3,NKAIN3,CADM1,PARD3B,NRXN1,CTNND2,QKI,AHCYL2,SLC1A2,ERBB4,NPAS3,SLC4A4,NHSL1,RYR3,MAML2,PREX2,NCKAP5,ATP13A4,RFX4,MSI2,NTM,ACSS1,LRIG1,ATP1A2,SLC1A3
8.086e-04	-7.12	human chr3q13.31	chromosome location	human chr3q13.31	22	2	26134	50	LSAMP,ZBTB20
8.975e-04	-7.02	presynaptic membrane	cellular component	GO:0042734	168	4	19108	49	ERBB4,NRXN1,GPM6A,SLC1A2
9.218e-04	-6.99	transporter activity	molecular function	GO:0005215	1211	10	18094	47	ATP13A4,SLC1A3,ATP1A2,SFXN5,ITPR2,SLC4A4,SLC1A2,PITPNC1,RYR3,GPM6A
9.531e-04	-6.96	bone-extraskeletal-Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour	COSMIC cancer mutations	bone-extraskeletal-Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour	891	9	16828	49	ABLIM1,NCKAP5,ITPR2,FGFR3,PTGDS,PTPRZ1,NPAS3,LRIG1,ATP1A2
9.636e-04	-6.94	Htt (huntingtin)	protein interactions	15194	77	3	19454	49	GPM6A,LSAMP,NTM
9.763e-04	-6.93	oligoastrocytoma_Grade_III	COSMIC cancer mutations	oligoastrocytoma_Grade_III	263	5	16828	49	SOX5,FGFR3,RYR3,SLC1A2,PREX2
9.840e-04	-6.92	acidic amino acid transmembrane transporter activity	molecular function	GO:0015172	18	2	18094	47	SLC1A3,SLC1A2
9.840e-04	-6.92	intracellularly gated calcium channel activity	molecular function	GO:0015278	18	2	18094	47	ITPR2,RYR3
9.998e-04	-6.91	skin-trunk-malignant_melanoma-nodular	COSMIC cancer mutations	skin-trunk-malignant_melanoma-nodular	1291	11	16828	49	HIF3A,PREX2,CDH20,NPAS3,PTPRZ1,ERBB4,CTNND2,ATP1A2,ATP13A4,ABLIM1,MACF1
1.028e-03	-6.88	soft_tissue	COSMIC cancer mutations	soft_tissue	5828	28	16828	49	NKAIN3,COL5A3,GPC5,GPM6A,RORA,ITPR2,LSAMP,PCDH9,MACF1,FBXL7,SOX5,PTPRZ1,TRPS1,NFIA,CDH20,SLC1A3,FGFR3,NCKAP5,PREX2,RYR3,MAML2,NHSL1,ERBB4,NPAS3,CTNND2,SLC1A2,PARD3B,CADM1
1.048e-03	-6.86	extraskeletal	COSMIC cancer mutations	extraskeletal	903	9	16828	49	LRIG1,ATP1A2,ABLIM1,NCKAP5,ITPR2,FGFR3,PTGDS,NPAS3,PTPRZ1
1.063e-03	-6.85	ATPase_P-typ_cation-transptr_N	interpro domains	IPR004014	18	2	18521	50	ATP13A4,ATP1A2
1.068e-03	-6.84	C11orf52 (chromosome 11 open reading frame 52)	protein interactions	91894	310	5	19454	49	ABLIM1,MACF1,AHCYL2,DTNA,TNIK
1.069e-03	-6.84	oesophagus-carcinoma-squamous_cell_carcinoma	COSMIC cancer mutations	oesophagus-carcinoma-squamous_cell_carcinoma	6486	30	16828	49	COL5A3,SFXN5,GPC5,GPM6A,ITPR2,PCDH9,ABLIM1,MACF1,TNIK,HIF3A,SOX5,FBXL7,PITPNC1,PTPRZ1,TRPS1,ATP1A2,ZBTB20,NCKAP5,FGFR3,ATP13A4,PREX2,SLC4A4,RYR3,MAML2,CTNND2,NPAS3,ERBB4,CADM1,PARD3B,NRXN1
1.112e-03	-6.80	monoatomic ion transport	biological process	GO:0006811	964	9	18204	50	SLC4A4,ATP13A4,RYR3,ITPR2,SLC1A2,SLC1A3,SFXN5,GPM6A,ATP1A2
1.150e-03	-6.77	Cation_ATPase_N	pfam domains	PF00690	18	2	17795	50	ATP13A4,ATP1A2
1.156e-03	-6.76	GSC (goosecoid homeobox)	protein interactions	145258	82	3	19454	49	NFIA,TRPS1,SOX5
1.173e-03	-6.75	solute:sodium symporter activity	molecular function	GO:0015370	80	3	18094	47	SLC1A3,SLC1A2,SLC4A4
1.186e-03	-6.74	PAS_fold	interpro domains	IPR013767	19	2	18521	50	NPAS3,HIF3A
1.209e-03	-6.72	serous_carcinoma	COSMIC cancer mutations	serous_carcinoma	10987	42	16828	49	CDH20,ZNF98,PTPRZ1,TRPS1,SOX5,FBXL7,TNIK,ITPR2,LSAMP,MACF1,PCDH9,PTGDS,RORA,SFXN5,GPC5,COL5A3,CADM1,NRXN1,PARD3B,CTNND2,AHCYL2,QKI,SLC1A2,ERBB4,NPAS3,NHSL1,SLC4A4,RYR3,MAML2,PREX2,NCKAP5,FGFR3,ATP13A4,MSI2,CST3,NTM,ACSS1,LRIG1,SLC1A3,ATP1A2,DTNA,ZBTB20
1.247e-03	-6.69	4.1m	smart domains	SM00294	14	2	9717	37	NRXN1,CADM1
1.252e-03	-6.68	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-peripheral_T_cell_lymphoma_unspecified	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-peripheral_T_cell_lymphoma_unspecified	162	4	16828	49	RYR3,MACF1,NCKAP5,ITPR2
1.283e-03	-6.66	PAS	pfam domains	PF00989	19	2	17795	50	HIF3A,NPAS3
1.284e-03	-6.66	arm	COSMIC cancer mutations	arm	1331	11	16828	49	PARD3B,TRPS1,NPAS3,ERBB4,SLC4A4,MACF1,FGFR3,NTM,ATP1A2,COL5A3,ZBTB20
1.289e-03	-6.65	cell morphogenesis involved in neuron differentiation	biological process	GO:0048667	443	6	18204	50	SLC1A3,CTNND2,NRXN1,PTPRZ1,CTNNA2,PREX2
1.295e-03	-6.65	stomach-carcinoma-diffuse_adenocarcinoma	COSMIC cancer mutations	stomach-carcinoma-diffuse_adenocarcinoma	4383	23	16828	49	ACSS1,SLC1A3,DTNA,ATP1A2,ABLIM1,MACF1,PCDH9,NCKAP5,FGFR3,RFX4,GPM6A,SOX5,HIF3A,NHSL1,RYR3,PREX2,CADM1,ZNF98,QKI,CTNND2,ERBB4,PTPRZ1,TRPS1
1.295e-03	-6.65	diffuse_adenocarcinoma	COSMIC cancer mutations	diffuse_adenocarcinoma	4383	23	16828	49	ABLIM1,MACF1,PCDH9,GPM6A,SOX5,HIF3A,ZNF98,TRPS1,PTPRZ1,ACSS1,SLC1A3,DTNA,ATP1A2,NCKAP5,FGFR3,RFX4,NHSL1,RYR3,PREX2,CADM1,CTNND2,QKI,ERBB4
1.361e-03	-6.60	adherens junction	cellular component	GO:0005912	188	4	19108	49	CTNNA2,CTNND2,CDH20,PARD3B
1.361e-03	-6.60	aspartate transmembrane transport	biological process	GO:0015810	20	2	18204	50	SLC1A2,SLC1A3
1.400e-03	-6.57	peripheral_T_cell_lymphoma_unspecified	COSMIC cancer mutations	peripheral_T_cell_lymphoma_unspecified	167	4	16828	49	RYR3,ITPR2,MACF1,NCKAP5
1.502e-03	-6.50	positive regulation of purine nucleotide catabolic process	biological process	GO:0033123	21	2	18204	50	ZBTB20,SLC4A4
1.502e-03	-6.50	positive regulation of nucleotide catabolic process	biological process	GO:0030813	21	2	18204	50	SLC4A4,ZBTB20
1.502e-03	-6.50	positive regulation of glycolytic process	biological process	GO:0045821	21	2	18204	50	ZBTB20,SLC4A4
1.517e-03	-6.49	skin-face-carcinoma-squamous_cell_carcinoma	COSMIC cancer mutations	skin-face-carcinoma-squamous_cell_carcinoma	2036	14	16828	49	PTPRZ1,ERBB4,TRPS1,PREX2,MSI2,RORA,GPM6A,LSAMP,ITPR2,MACF1,PCDH9,ABLIM1,FGFR3,GPC5
1.520e-03	-6.49	Rbm38 (RNA binding motif protein 38)	protein interactions	56190	23	2	19454	49	MSI2,QKI
1.614e-03	-6.43	amino acid:sodium symporter activity	molecular function	GO:0005283	23	2	18094	47	SLC1A3,SLC1A2
1.632e-03	-6.42	cellular response to organic cyclic compound	biological process	GO:0071407	464	6	18204	50	ATP1A2,SLC1A3,SLC1A2,ITPR2,RORA,RYR3
1.637e-03	-6.41	Cation_ATPase_N	smart domains	SM00831	16	2	9717	37	ATP13A4,ATP1A2
1.649e-03	-6.41	intracellular sodium ion homeostasis	biological process	GO:0006883	22	2	18204	50	ATP1A2,SLC1A3
1.664e-03	-6.40	monoatomic cation transmembrane transport	biological process	GO:0098655	636	7	18204	50	ATP1A2,GPM6A,SLC1A3,ITPR2,ATP13A4,SLC4A4,RYR3
1.688e-03	-6.38	forearm	COSMIC cancer mutations	forearm	81	3	16828	49	FGFR3,PREX2,ERBB4
1.740e-03	-6.35	middle_lobe	COSMIC cancer mutations	middle_lobe	1382	11	16828	49	RYR3,PARD3B,ERBB4,CTNND2,ATP1A2,ATP13A4,FGFR3,PCDH9,NCKAP5,MACF1,ITPR2
1.751e-03	-6.35	neuron projection	cellular component	GO:0043005	1331	10	19108	49	CADM1,AHCYL2,SLC1A3,CTNNA2,PCDH9,SLC1A2,CTNND2,DTNA,GPM6A,ATP1A2
1.757e-03	-6.34	P-type transmembrane transporter activity	molecular function	GO:0140358	24	2	18094	47	ATP13A4,ATP1A2
1.757e-03	-6.34	P-type ion transporter activity	molecular function	GO:0015662	24	2	18094	47	ATP13A4,ATP1A2
1.913e-03	-6.26	human chr15q13.3-q14	chromosome location	human chr15q13.3-q14	1	1	26134	50	RYR3
1.913e-03	-6.26	human chr3q26.2-q26.31	chromosome location	human chr3q26.2-q26.31	1	1	26134	50	TNIK
1.920e-03	-6.26	urinary_tract-bladder-carcinoma-transitional_cell_carcinoma	COSMIC cancer mutations	urinary_tract-bladder-carcinoma-transitional_cell_carcinoma	6040	28	16828	49	GPM6A,ITPR2,MACF1,PCDH9,ABLIM1,COL5A3,SFXN5,GPC5,PTPRZ1,NFIA,TRPS1,CDH20,HIF3A,RFX4,FGFR3,ATP13A4,DTNA,ATP1A2,SLC1A3,ZBTB20,LRIG1,ACSS1,ERBB4,CADM1,PARD3B,NRXN1,PREX2,SLC4A4
1.928e-03	-6.25	anchoring junction	cellular component	GO:0070161	902	8	19108	49	CADM1,CTNNA2,PCDH9,FGFR3,PARD3B,CDH20,CTNND2,ATP1A2
1.931e-03	-6.25	transitional_cell_carcinoma	COSMIC cancer mutations	transitional_cell_carcinoma	6042	28	16828	49	GPM6A,ABLIM1,MACF1,PCDH9,ITPR2,COL5A3,GPC5,SFXN5,NFIA,TRPS1,PTPRZ1,CDH20,HIF3A,RFX4,ATP13A4,FGFR3,ZBTB20,ATP1A2,SLC1A3,DTNA,ACSS1,LRIG1,ERBB4,PARD3B,NRXN1,CADM1,PREX2,SLC4A4
1.940e-03	-6.25	LYN (LYN proto-oncogene, Src family tyrosine kinase)	protein interactions	4067	713	7	19454	49	SLC1A3,MSI2,TNIK,ERBB4,MACF1,DTNA,ABLIM1
1.957e-03	-6.24	bone-femur-other-chondroblastoma	COSMIC cancer mutations	bone-femur-other-chondroblastoma	183	4	16828	49	NCKAP5,PCDH9,RYR3,GPC5
1.959e-03	-6.24	transmembrane transporter activity	molecular function	GO:0022857	1110	9	18094	47	ITPR2,SLC4A4,SLC1A2,SLC1A3,ATP1A2,ATP13A4,SFXN5,RYR3,GPM6A
1.978e-03	-6.23	IGc2	smart domains	SM00408	239	5	9717	37	FGFR3,LRIG1,LSAMP,CADM1,NTM
1.997e-03	-6.22	Proximal tubule bicarbonate reclamation	KEGG pathways	ko04964	23	2	7161	21	ATP1A2,SLC4A4
1.997e-03	-6.22	Proximal tubule bicarbonate reclamation	KEGG pathways	hsa04964	23	2	7161	21	ATP1A2,SLC4A4
2.018e-03	-6.21	back	COSMIC cancer mutations	back	310	5	16828	49	FGFR3,ATP1A2,PREX2,ERBB4,TNIK
2.021e-03	-6.20	skin-face-malignant_melanoma-lentigo_maligna	COSMIC cancer mutations	skin-face-malignant_melanoma-lentigo_maligna	23	2	16828	49	FGFR3,PREX2
2.048e-03	-6.19	NCK1 (NCK adaptor protein 1)	protein interactions	4690	214	4	19454	49	NCKAP5,NHSL1,ERBB4,TNIK
2.095e-03	-6.17	KCNJ12 (potassium inwardly rectifying channel subfamily J member 12)	protein interactions	3768	27	2	19454	49	ABLIM1,DTNA
2.095e-03	-6.17	MBNL2 (muscleblind like splicing regulator 2)	protein interactions	10150	27	2	19454	49	QKI,MSI2
2.130e-03	-6.15	L-glutamate transmembrane transport	biological process	GO:0015813	25	2	18204	50	SLC1A2,SLC1A3
2.146e-03	-6.14	synapse organization	biological process	GO:0050808	333	5	18204	50	GPM6A,ERBB4,CTNND2,NFIA,NRXN1
2.152e-03	-6.14	extrinsic component of plasma membrane	cellular component	GO:0019897	100	3	19108	49	DTNA,CTNNA2,CDH20
2.181e-03	-6.13	Glutamate Neurotransmitter Release Cycle	REACTOME pathways	R-HSA-210500	24	2	10285	30	SLC1A2,SLC1A3
2.196e-03	-6.12	adenoma	COSMIC cancer mutations	adenoma	2873	17	16828	49	COL5A3,ZBTB20,ACSS1,GPC5,GPM6A,NCKAP5,MACF1,PCDH9,FGFR3,HIF3A,SOX5,RYR3,CTNND2,PTPRZ1,NPAS3,ERBB4,CDH20
2.253e-03	-6.10	LRRC7 (leucine rich repeat containing 7)	protein interactions	57554	28	2	19454	49	CTNND2,ERBB4
2.287e-03	-6.08	NS-malignant_melanoma	COSMIC cancer mutations	NS-malignant_melanoma	3420	19	16828	49	GPC5,LRIG1,COL5A3,ATP1A2,ITPR2,PCDH9,MACF1,NCKAP5,FGFR3,ATP13A4,RFX4,PREX2,CADM1,NRXN1,ZNF98,CTNND2,PITPNC1,ERBB4,PTPRZ1
2.299e-03	-6.08	inorganic molecular entity transmembrane transporter activity	molecular function	GO:0015318	714	7	18094	47	GPM6A,RYR3,SLC1A3,ATP1A2,SLC1A2,SLC4A4,ITPR2
2.304e-03	-6.07	C4-dicarboxylate transport	biological process	GO:0015740	26	2	18204	50	SLC1A3,SLC1A2
2.414e-03	-6.03	hairy_cell_leukaemia	COSMIC cancer mutations	hairy_cell_leukaemia	1440	11	16828	49	CDH20,NRXN1,FGFR3,MACF1,NCKAP5,PTPRZ1,RFX4,CTNND2,RYR3,PREX2,COL5A3
2.414e-03	-6.03	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-hairy_cell_leukaemia	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-hairy_cell_leukaemia	1440	11	16828	49	RYR3,PREX2,CDH20,NRXN1,PTPRZ1,CTNND2,COL5A3,FGFR3,MACF1,NCKAP5,RFX4
2.417e-03	-6.03	MAPRE3 (microtubule associated protein RP/EB family member 3)	protein interactions	22924	224	4	19454	49	GPM6A,ABLIM1,MACF1,NCKAP5
2.435e-03	-6.02	face	COSMIC cancer mutations	face	2139	14	16828	49	ERBB4,PTPRZ1,TRPS1,PREX2,ITPR2,LSAMP,MACF1,ABLIM1,PCDH9,FGFR3,RORA,MSI2,GPM6A,GPC5
2.478e-03	-6.00	Calcium-transporting ATPase, transmembrane domain	gene3d domains	1.20.1110.10	25	2	14470	43	ATP13A4,ATP1A2
2.504e-03	-5.99	skin-trunk-malignant_melanoma	COSMIC cancer mutations	skin-trunk-malignant_melanoma	2647	16	16828	49	CTNND2,TRPS1,ERBB4,PTPRZ1,CDH20,NRXN1,PREX2,SOX5,RYR3,MAML2,NCKAP5,PCDH9,LSAMP,ATP13A4,SLC1A3,ATP1A2
2.519e-03	-5.98	Agtrap (angiotensin II, type I receptor-associated protein)	protein interactions	11610	1	1	19454	49	PITPNC1
2.519e-03	-5.98	Sh2b1 (SH2B adaptor protein 1)	protein interactions	20399	1	1	19454	49	FGFR3
2.519e-03	-5.98	fgf3.L (fibroblast growth factor 3 L homeolog)	protein interactions	373669	1	1	19454	49	FGFR3
2.519e-03	-5.98	Sytl1 (synaptotagmin-like 1)	protein interactions	269589	1	1	19454	49	NRXN1
2.530e-03	-5.98	Pancreatic secretion	KEGG pathways	ko04972	95	3	7161	21	ATP1A2,ITPR2,SLC4A4
2.530e-03	-5.98	Pancreatic secretion	KEGG pathways	hsa04972	95	3	7161	21	ATP1A2,ITPR2,SLC4A4
2.546e-03	-5.97	EN1 (engrailed homeobox 1)	protein interactions	2019	108	3	19454	49	NFIA,AHCYL2,TRPS1
2.546e-03	-5.97	FKBP1A (FKBP prolyl isomerase 1A)	protein interactions	2280	108	3	19454	49	RYR3,MSI2,ERBB4
2.564e-03	-5.97	ligand-gated calcium channel activity	molecular function	GO:0099604	29	2	18094	47	RYR3,ITPR2
2.564e-03	-5.97	amino acid:monoatomic cation symporter activity	molecular function	GO:0005416	29	2	18094	47	SLC1A2,SLC1A3
2.577e-03	-5.96	upper_back	COSMIC cancer mutations	upper_back	328	5	16828	49	MACF1,GPC5,PARD3B,FGFR3,ERBB4
2.579e-03	-5.96	bone-tibia-Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour	COSMIC cancer mutations	bone-tibia-Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour	649	7	16828	49	QKI,TNIK,PREX2,ABLIM1,MACF1,FGFR3,ACSS1
2.598e-03	-5.95	internal N(7)-methylguanine-containing RNA reader activity	molecular function	GO:0160089	1	1	18094	47	QKI
2.614e-03	-5.95	response to alkaloid	biological process	GO:0043279	100	3	18204	50	SLC1A3,SLC1A2,RYR3
2.670e-03	-5.93	positive regulation of oligodendrocyte differentiation	biological process	GO:0048714	28	2	18204	50	QKI,PTPRZ1
2.671e-03	-5.93	human chr20p11.21	chromosome location	human chr20p11.21	40	2	26134	50	CST3,ACSS1
2.700e-03	-5.91	STAR_dimer	interpro domains	IPR032377	1	1	18521	50	QKI
2.700e-03	-5.91	Rex2_DEP_1	interpro domains	IPR037367	1	1	18521	50	PREX2
2.700e-03	-5.91	Quaking_NLS	interpro domains	IPR032367	1	1	18521	50	QKI
2.700e-03	-5.91	MAML2_TAD	interpro domains	IPR048452	1	1	18521	50	MAML2
2.700e-03	-5.91	TRPS1	interpro domains	IPR028440	1	1	18521	50	TRPS1
2.701e-03	-5.91	neuron projection development	biological process	GO:0031175	693	7	18204	50	GPM6A,PTPRZ1,PREX2,CTNNA2,CTNND2,NRXN1,TNIK
2.709e-03	-5.91	large_intestine-caecum-carcinoma-adenocarcinoma	COSMIC cancer mutations	large_intestine-caecum-carcinoma-adenocarcinoma	14236	48	16828	49	TNIK,FBXL7,HIF3A,PTPRZ1,NFIA,ZNF98,PITPNC1,CDH20,GPM6A,ITPR2,LSAMP,PCDH9,MACF1,RYR3,SLC4A4,NHSL1,CADM1,ZBTB20,DTNA,SLC1A3,ATP1A2,LRIG1,NTM,SOX5,TRPS1,NKAIN3,COL5A3,GPC5,SFXN5,RORA,PTGDS,ABLIM1,PREX2,MAML2,ERBB4,NPAS3,CTNND2,AHCYL2,QKI,SLC1A2,PARD3B,NRXN1,ACSS1,CST3,RFX4,FGFR3,ATP13A4,NCKAP5
2.747e-03	-5.90	olfactory cortex development	biological process	GO:0021989	1	1	18204	50	ATP1A2
2.747e-03	-5.90	negative regulation of calcium:sodium antiporter activity	biological process	GO:1903280	1	1	18204	50	ATP1A2
2.747e-03	-5.90	negative regulation of collagen catabolic process	biological process	GO:0010711	1	1	18204	50	CST3
2.747e-03	-5.90	negative regulation of elastin catabolic process	biological process	GO:0060311	1	1	18204	50	CST3
2.758e-03	-5.89	SH2D1B (SH2 domain containing 1B)	protein interactions	117157	31	2	19454	49	ERBB4,ABLIM1
2.758e-03	-5.89	SH2B1 (SH2B adaptor protein 1)	protein interactions	25970	31	2	19454	49	FGFR3,ERBB4
2.783e-03	-5.88	Transmembrane transport of small molecules	REACTOME pathways	R-HSA-382551	677	7	10285	30	SLC1A3,ATP1A2,ATP13A4,RYR3,AHCYL2,SLC1A2,SLC4A4
2.809e-03	-5.87	caecum	COSMIC cancer mutations	caecum	14248	48	16828	49	CADM1,RYR3,NHSL1,SLC4A4,LRIG1,NTM,ZBTB20,SLC1A3,DTNA,ATP1A2,CDH20,PTPRZ1,NFIA,ZNF98,PITPNC1,FBXL7,HIF3A,TNIK,LSAMP,ITPR2,PCDH9,MACF1,GPM6A,NRXN1,PARD3B,ERBB4,NPAS3,CTNND2,QKI,AHCYL2,SLC1A2,MAML2,PREX2,FGFR3,ATP13A4,NCKAP5,CST3,RFX4,ACSS1,TRPS1,SOX5,PTGDS,ABLIM1,RORA,GPC5,SFXN5,NKAIN3,COL5A3
2.810e-03	-5.87	FGFR3_TM	pfam domains	PF21165	1	1	17795	50	FGFR3
2.810e-03	-5.87	STAR_dimer	pfam domains	PF16544	1	1	17795	50	QKI
2.810e-03	-5.87	MAML2_TAD	pfam domains	PF20804	1	1	17795	50	MAML2
2.810e-03	-5.87	Quaking_NLS	pfam domains	PF16551	1	1	17795	50	QKI
2.823e-03	-5.87	TBR1 (T-box brain transcription factor 1)	protein interactions	10716	112	3	19454	49	SOX5,TRPS1,NFIA
2.857e-03	-5.86	cell body	cellular component	GO:0044297	556	6	19108	49	SLC1A2,SLC1A3,NRXN1,ATP1A2,GPM6A,CTNND2
2.857e-03	-5.86	catenin complex	cellular component	GO:0016342	31	2	19108	49	CDH20,CTNNA2
2.917e-03	-5.84	t(4;14) translocations of FGFR3	REACTOME pathways	R-HSA-2033515	1	1	10285	30	FGFR3
2.927e-03	-5.83	intracellularly ligand-gated monoatomic ion channel activity	molecular function	GO:0005217	31	2	18094	47	RYR3,ITPR2
2.937e-03	-5.83	NXPH2 (neurexophilin 2)	protein interactions	11249	32	2	19454	49	NRXN1,PCDH9
2.968e-03	-5.82	ORF3b (ORF3b protein)	protein interactions	1489670	114	3	19454	49	ZBTB20,MACF1,PCDH9
2.972e-03	-5.82	-	gene3d domains	1.20.5.4010	1	1	14470	43	QKI
2.972e-03	-5.82	-	gene3d domains	6.10.250.880	1	1	14470	43	ERBB4
2.972e-03	-5.82	-	gene3d domains	6.10.250.1740	1	1	14470	43	FGFR3
3.002e-03	-5.81	neural precursor cell proliferation	biological process	GO:0061351	105	3	18204	50	NFIA,SOX5,RORA
3.009e-03	-5.81	GJA1 (gap junction protein alpha 1)	protein interactions	2697	572	6	19454	49	PCDH9,MACF1,ITPR2,ERBB4,TNIK,DTNA
3.028e-03	-5.80	plasma_cell_myeloma	COSMIC cancer mutations	plasma_cell_myeloma	1263	10	16828	49	GPM6A,TRPS1,CTNND2,ATP13A4,FGFR3,ABLIM1,MACF1,TNIK,RYR3,NTM
3.028e-03	-5.80	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-plasma_cell_myeloma	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-plasma_cell_myeloma	1263	10	16828	49	FGFR3,ATP13A4,ABLIM1,MACF1,GPM6A,TRPS1,CTNND2,RYR3,NTM,TNIK
3.062e-03	-5.79	L-glutamate import	biological process	GO:0051938	30	2	18204	50	SLC1A3,SLC1A2
3.131e-03	-5.77	chronic_lymphocytic_leukaemia-small_lymphocytic_lymphoma	COSMIC cancer mutations	chronic_lymphocytic_leukaemia-small_lymphocytic_lymphoma	3511	19	16828	49	SLC4A4,RYR3,FBXL7,PREX2,TNIK,PARD3B,PITPNC1,CTNND2,ERBB4,NPAS3,PTPRZ1,GPC5,SLC1A3,DTNA,MACF1,PCDH9,NCKAP5,LSAMP,MSI2
3.131e-03	-5.77	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-chronic_lymphocytic_leukaemia-small_lymphocytic_lymphoma	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-chronic_lymphocytic_leukaemia-small_lymphocytic_lymphoma	3511	19	16828	49	FBXL7,RYR3,SLC4A4,PREX2,TNIK,PARD3B,NPAS3,ERBB4,PTPRZ1,CTNND2,PITPNC1,GPC5,SLC1A3,DTNA,LSAMP,MACF1,PCDH9,NCKAP5,MSI2
3.219e-03	-5.74	skin-leg-malignant_melanoma-superficial_spreading	COSMIC cancer mutations	skin-leg-malignant_melanoma-superficial_spreading	210	4	16828	49	NTM,SLC4A4,ATP13A4,COL5A3
3.234e-03	-5.73	cell junction organization	biological process	GO:0034330	532	6	18204	50	GPM6A,CDH20,CTNND2,ERBB4,NRXN1,NFIA
3.404e-03	-5.68	cellular response to endogenous stimulus	biological process	GO:0071495	1135	9	18204	50	ITPR2,ERBB4,RYR3,NFIA,ATP1A2,FGFR3,SLC1A2,SLC1A3,SOX5
3.415e-03	-5.68	E1-E2_ATPase	pfam domains	PF00122	31	2	17795	50	ATP13A4,ATP1A2
3.430e-03	-5.68	lentigo_maligna	COSMIC cancer mutations	lentigo_maligna	30	2	16828	49	PREX2,FGFR3
3.430e-03	-5.68	skin-malignant_melanoma-acral_lentiginous	COSMIC cancer mutations	skin-malignant_melanoma-acral_lentiginous	30	2	16828	49	PREX2,FGFR3
3.445e-03	-5.67	brain development	biological process	GO:0007420	724	7	18204	50	CTNNA2,RFX4,ATP1A2,PCDH9,RORA,SLC1A2,ERBB4
3.473e-03	-5.66	calcium channel activity	molecular function	GO:0005262	117	3	18094	47	ITPR2,RYR3,GPM6A
3.473e-03	-5.66	solute:monoatomic cation symporter activity	molecular function	GO:0015294	117	3	18094	47	SLC1A3,SLC1A2,SLC4A4
3.479e-03	-5.66	positive regulation of ATP metabolic process	biological process	GO:1903580	32	2	18204	50	SLC4A4,ZBTB20
3.479e-03	-5.66	transepithelial transport	biological process	GO:0070633	32	2	18204	50	SLC1A2,SLC1A3
3.624e-03	-5.62	upper_leg	COSMIC cancer mutations	upper_leg	880	8	16828	49	NFIA,ERBB4,FGFR3,PCDH9,PREX2,ACSS1,LRIG1,HIF3A
3.637e-03	-5.62	Cation_ATPase	pfam domains	PF13246	32	2	17795	50	ATP1A2,ATP13A4
3.674e-03	-5.61	cell-cell adhesion	biological process	GO:0098609	546	6	18204	50	NRXN1,CTNND2,CDH20,CADM1,CTNNA2,PCDH9
3.692e-03	-5.60	dendrite development	biological process	GO:0016358	113	3	18204	50	CTNNA2,PREX2,CTNND2
3.721e-03	-5.59	organic acid:sodium symporter activity	molecular function	GO:0005343	35	2	18094	47	SLC1A2,SLC1A3
3.758e-03	-5.58	plasma membrane bounded cell projection organization	biological process	GO:0120036	1152	9	18204	50	TNIK,RFX4,PTPRZ1,GPM6A,CTNNA2,PREX2,CTNND2,NRXN1,ABLIM1
3.792e-03	-5.57	PAS-like_dom_sf	interpro domains	IPR035965	34	2	18521	50	NPAS3,HIF3A
3.792e-03	-5.57	PAS	interpro domains	IPR000014	34	2	18521	50	NPAS3,HIF3A
3.808e-03	-5.57	DELLA	smart domains	SM01129	1	1	9717	37	MACF1
3.879e-03	-5.55	fatty acid biosynthetic process	biological process	GO:0006633	115	3	18204	50	QKI,ACSS1,PTGDS
3.897e-03	-5.55	skin-arm-malignant_melanoma	COSMIC cancer mutations	skin-arm-malignant_melanoma	1308	10	16828	49	ZBTB20,COL5A3,ATP1A2,SLC4A4,NTM,ERBB4,NPAS3,TRPS1,PARD3B,MACF1
3.913e-03	-5.54	TRNAU1AP (tRNA selenocysteine 1 associated protein 1)	protein interactions	54952	37	2	19454	49	ZBTB20,QKI
3.913e-03	-5.54	HPCA (hippocalcin)	protein interactions	3208	37	2	19454	49	CST3,GPM6A
3.913e-03	-5.54	MAGI2 (membrane associated guanylate kinase, WW and PDZ domain containing 2)	protein interactions	9863	37	2	19454	49	CTNND2,ERBB4
3.932e-03	-5.54	Diseases of signal transduction	REACTOME pathways	R-HSA-5663202	369	5	10285	30	MAML2,FGFR3,MACF1,ERBB4,QKI
4.005e-03	-5.52	PAS	smart domains	SM00091	25	2	9717	37	HIF3A,NPAS3
4.010e-03	-5.52	TRIM67 (tripartite motif containing 67)	protein interactions	440730	4804	21	19454	49	ATP1A2,CTNND2,DTNA,QKI,PTPRZ1,ITPR2,LSAMP,MSI2,CST3,AHCYL2,SLC1A3,SLC4A4,LRIG1,PITPNC1,GPM6A,ACSS1,CADM1,MACF1,CTNNA2,NTM,TNIK
4.021e-03	-5.52	EPB41L4A (erythrocyte membrane protein band 4.1 like 4A)	protein interactions	64097	127	3	19454	49	ABLIM1,MACF1,DTNA
4.021e-03	-5.52	PAX9 (paired box 9)	protein interactions	5083	127	3	19454	49	QKI,NFIA,TRPS1
4.102e-03	-5.50	Ig_sub	interpro domains	IPR003599	394	5	18521	50	FGFR3,CADM1,LRIG1,LSAMP,NTM
4.111e-03	-5.49	ATF7IP (activating transcription factor 7 interacting protein)	protein interactions	55729	128	3	19454	49	MACF1,CADM1,SOX5
4.123e-03	-5.49	Pcbp1 (poly(rC) binding protein 1)	protein interactions	23983	38	2	19454	49	MSI2,QKI
4.158e-03	-5.48	FGFR1 (fibroblast growth factor receptor 1)	protein interactions	2260	611	6	19454	49	DTNA,AHCYL2,TNIK,FGFR3,ABLIM1,NHSL1
4.169e-03	-5.48	synapse assembly	biological process	GO:0007416	118	3	18204	50	GPM6A,ERBB4,NRXN1
4.193e-03	-5.47	transcription cis-regulatory region binding	molecular function	GO:0000976	1485	10	18094	47	RORA,SOX5,ERBB4,ZBTB20,ZNF98,RFX4,NPAS3,NFIA,TRPS1,HIF3A
4.201e-03	-5.47	Lima1 (LIM domain and actin binding 1)	protein interactions	65970	129	3	19454	49	ZBTB20,ABLIM1,ITPR2
4.234e-03	-5.46	transcription regulatory region nucleic acid binding	molecular function	GO:0001067	1487	10	18094	47	ZBTB20,ZNF98,RFX4,NFIA,NPAS3,TRPS1,HIF3A,RORA,SOX5,ERBB4
4.240e-03	-5.46	Glutamatergic synapse	KEGG pathways	hsa04724	114	3	7161	21	SLC1A2,SLC1A3,ITPR2
4.240e-03	-5.46	Glutamatergic synapse	KEGG pathways	ko04724	114	3	7161	21	SLC1A2,SLC1A3,ITPR2
4.244e-03	-5.46	ATPase_P-typ_P_site	interpro domains	IPR018303	36	2	18521	50	ATP1A2,ATP13A4
4.244e-03	-5.46	ATPase_P-typ_transduc_dom_A_sf	interpro domains	IPR008250	36	2	18521	50	ATP13A4,ATP1A2
4.244e-03	-5.46	P_typ_ATPase_HD_dom	interpro domains	IPR044492	36	2	18521	50	ATP13A4,ATP1A2
4.244e-03	-5.46	P_typ_ATPase	interpro domains	IPR001757	36	2	18521	50	ATP13A4,ATP1A2
4.244e-03	-5.46	ATPase_P-typ_cyto_dom_N	interpro domains	IPR023299	36	2	18521	50	ATP13A4,ATP1A2
4.257e-03	-5.46	response to endogenous stimulus	biological process	GO:0009719	1402	10	18204	50	PTGDS,ITPR2,NFIA,ERBB4,RYR3,FGFR3,ATP1A2,SOX5,SLC1A3,SLC1A2
4.289e-03	-5.45	superficial_spreading	COSMIC cancer mutations	superficial_spreading	1110	9	16828	49	NTM,SLC4A4,COL5A3,PREX2,MACF1,ATP13A4,FGFR3,CTNND2,ERBB4
4.335e-03	-5.44	kidney-other-neoplasm	COSMIC cancer mutations	kidney-other-neoplasm	10653	40	16828	49	SFXN5,GPC5,COL5A3,NKAIN3,PCDH9,ABLIM1,MACF1,ITPR2,LSAMP,RORA,GPM6A,SOX5,FBXL7,TNIK,CDH20,ZNF98,TRPS1,PTPRZ1,LRIG1,ACSS1,DTNA,ATP1A2,SLC1A3,ZBTB20,NCKAP5,ATP13A4,FGFR3,RFX4,NHSL1,RYR3,MAML2,PREX2,CADM1,NRXN1,SLC1A2,AHCYL2,QKI,CTNND2,ERBB4,NPAS3
4.370e-03	-5.43	striated muscle contraction	biological process	GO:0006941	120	3	18204	50	ATP1A2,DTNA,RYR3
4.391e-03	-5.43	central_nervous_system-parietal_lobe-glioma-astrocytoma_Grade_I	COSMIC cancer mutations	central_nervous_system-parietal_lobe-glioma-astrocytoma_Grade_I	34	2	16828	49	FGFR3,QKI
4.470e-03	-5.41	central_nervous_system-brain-primitive_neuroectodermal_tumour-medulloblastoma-large_cell	COSMIC cancer mutations	central_nervous_system-brain-primitive_neuroectodermal_tumour-medulloblastoma-large_cell	1117	9	16828	49	ERBB4,QKI,SLC1A2,ATP13A4,CDH20,NCKAP5,GPC5,RYR3,SOX5
4.478e-03	-5.41	ATPase_P-typ_TM_dom_sf	interpro domains	IPR023298	37	2	18521	50	ATP13A4,ATP1A2
4.574e-03	-5.39	RHOB (ras homolog family member B)	protein interactions	388	832	7	19454	49	SLC1A3,AHCYL2,TNIK,PARD3B,MACF1,DTNA,ABLIM1
4.631e-03	-5.38	positive regulation of purine nucleotide metabolic process	biological process	GO:1900544	37	2	18204	50	SLC4A4,ZBTB20
4.631e-03	-5.38	positive regulation of nucleotide metabolic process	biological process	GO:0045981	37	2	18204	50	ZBTB20,SLC4A4
4.632e-03	-5.37	prostate-carcinoma-adenocarcinoma	COSMIC cancer mutations	prostate-carcinoma-adenocarcinoma	12379	44	16828	49	SLC1A3,ATP1A2,ZBTB20,NTM,LRIG1,CADM1,NHSL1,RYR3,GPM6A,MACF1,PCDH9,ITPR2,LSAMP,PITPNC1,ZNF98,NFIA,PTPRZ1,CDH20,TNIK,HIF3A,FBXL7,RFX4,NCKAP5,ATP13A4,FGFR3,ACSS1,SLC1A2,QKI,CTNND2,AHCYL2,NPAS3,ERBB4,PARD3B,NRXN1,PREX2,MAML2,RORA,ABLIM1,COL5A3,NKAIN3,SFXN5,GPC5,TRPS1,SOX5
4.668e-03	-5.37	bone-fibula-Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour	COSMIC cancer mutations	bone-fibula-Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour	377	5	16828	49	COL5A3,MACF1,NCKAP5,FGFR3,NRXN1
4.691e-03	-5.36	monoatomic cation transport	biological process	GO:0006812	766	7	18204	50	SLC1A3,ATP1A2,GPM6A,RYR3,SLC4A4,ATP13A4,ITPR2
4.745e-03	-5.35	PAS	prosite domains	PS50112	30	2	12186	42	NPAS3,HIF3A
4.770e-03	-5.35	Myo1c (myosin IC)	protein interactions	17913	135	3	19454	49	ABLIM1,ITPR2,TRPS1
4.770e-03	-5.35	NTRK2 (neurotrophic receptor tyrosine kinase 2)	protein interactions	4915	135	3	19454	49	DTNA,ABLIM1,ERBB4
4.783e-03	-5.34	lung-carcinoma-small_cell_carcinoma	COSMIC cancer mutations	lung-carcinoma-small_cell_carcinoma	9908	38	16828	49	GPM6A,RORA,ITPR2,PCDH9,ABLIM1,MACF1,COL5A3,NKAIN3,GPC5,PITPNC1,PTPRZ1,TRPS1,NFIA,CDH20,TNIK,HIF3A,SOX5,FBXL7,RFX4,CST3,MSI2,FGFR3,ATP13A4,DTNA,ATP1A2,NTM,LRIG1,CTNND2,QKI,AHCYL2,ERBB4,NPAS3,NRXN1,PARD3B,PREX2,SLC4A4,MAML2,RYR3
4.840e-03	-5.33	small_cell_carcinoma	COSMIC cancer mutations	small_cell_carcinoma	9913	38	16828	49	ITPR2,ABLIM1,PCDH9,MACF1,RORA,GPM6A,GPC5,NKAIN3,COL5A3,CDH20,PTPRZ1,TRPS1,NFIA,PITPNC1,FBXL7,SOX5,HIF3A,TNIK,FGFR3,ATP13A4,MSI2,CST3,RFX4,LRIG1,NTM,ATP1A2,DTNA,NRXN1,PARD3B,ERBB4,NPAS3,AHCYL2,CTNND2,QKI,RYR3,MAML2,SLC4A4,PREX2
4.880e-03	-5.32	amino acid import across plasma membrane	biological process	GO:0089718	38	2	18204	50	SLC1A2,SLC1A3
4.912e-03	-5.32	central_nervous_system-thalamus-glioma-astrocytoma_Grade_I	COSMIC cancer mutations	central_nervous_system-thalamus-glioma-astrocytoma_Grade_I	36	2	16828	49	FGFR3,QKI
4.915e-03	-5.32	cell projection organization	biological process	GO:0030030	1200	9	18204	50	RFX4,GPM6A,PTPRZ1,PREX2,CTNNA2,CTNND2,ABLIM1,NRXN1,TNIK
4.963e-03	-5.31	head development	biological process	GO:0060322	774	7	18204	50	SLC1A2,CTNNA2,ATP1A2,RFX4,RORA,ERBB4,PCDH9
4.969e-03	-5.30	intracellular chemical homeostasis	biological process	GO:0055082	581	6	18204	50	RYR3,SLC1A3,ATP13A4,SLC4A4,ZBTB20,ATP1A2
5.031e-03	-5.29	cdh11.S (cadherin 11 S homeolog)	protein interactions	100337621	2	1	19454	49	ERBB4
5.070e-03	-5.28	NFIB (nuclear factor I B)	protein interactions	4781	138	3	19454	49	NFIA,SOX5,TRPS1
5.093e-03	-5.28	organic anion transmembrane transporter activity	molecular function	GO:0008514	268	4	18094	47	SLC4A4,SLC1A2,SFXN5,SLC1A3
5.097e-03	-5.28	Calcium-transporting ATPase, cytoplasmic transduction domain A	gene3d domains	2.70.150.10	36	2	14470	43	ATP13A4,ATP1A2
5.097e-03	-5.28	Calcium-transporting ATPase, cytoplasmic domain N	gene3d domains	3.40.1110.10	36	2	14470	43	ATP13A4,ATP1A2
5.109e-03	-5.28	forebrain development	biological process	GO:0030900	408	5	18204	50	ERBB4,SLC1A2,PCDH9,ATP1A2,RFX4
5.134e-03	-5.27	olfactory lobe development	biological process	GO:0021988	39	2	18204	50	ATP1A2,ERBB4
5.134e-03	-5.27	sodium ion homeostasis	biological process	GO:0055078	39	2	18204	50	ATP1A2,SLC1A3
5.135e-03	-5.27	prostate	COSMIC cancer mutations	prostate	13883	47	16828	49	TRPS1,SOX5,ABLIM1,RORA,SFXN5,GPC5,COL5A3,NKAIN3,NRXN1,PARD3B,SLC1A2,CTNND2,AHCYL2,QKI,NPAS3,ERBB4,MAML2,PREX2,NCKAP5,ATP13A4,FGFR3,RFX4,MSI2,ACSS1,CDH20,PITPNC1,ZNF98,NFIA,PTPRZ1,HIF3A,FBXL7,TNIK,MACF1,PCDH9,ITPR2,LSAMP,GPM6A,CADM1,SLC4A4,NHSL1,RYR3,NTM,LRIG1,DTNA,ATP1A2,SLC1A3,ZBTB20
5.154e-03	-5.27	spindle	COSMIC cancer mutations	spindle	386	5	16828	49	CTNND2,PREX2,MACF1,PCDH9,FGFR3
5.184e-03	-5.26	central_nervous_system-third_ventricle-glioma-astrocytoma_Grade_I	COSMIC cancer mutations	central_nervous_system-third_ventricle-glioma-astrocytoma_Grade_I	37	2	16828	49	FGFR3,QKI
5.210e-03	-5.26	fibula	COSMIC cancer mutations	fibula	387	5	16828	49	COL5A3,NRXN1,FGFR3,NCKAP5,MACF1
5.251e-03	-5.25	oligoastrocytoma_Grade_II	COSMIC cancer mutations	oligoastrocytoma_Grade_II	121	3	16828	49	CDH20,FGFR3,DTNA
5.290e-03	-5.24	calcium ion transmembrane transporter activity	molecular function	GO:0015085	136	3	18094	47	RYR3,ITPR2,GPM6A
5.302e-03	-5.24	lung-left_upper_lobe-carcinoma-adenocarcinoma	COSMIC cancer mutations	lung-left_upper_lobe-carcinoma-adenocarcinoma	556	6	16828	49	RYR3,FBXL7,SLC4A4,TRPS1,ERBB4,CTNND2
5.322e-03	-5.24	neutral L-amino acid transmembrane transporter activity	molecular function	GO:0015175	42	2	18094	47	SLC1A2,SLC1A3
5.356e-03	-5.23	lung-middle_lobe-carcinoma-adenocarcinoma	COSMIC cancer mutations	lung-middle_lobe-carcinoma-adenocarcinoma	1368	10	16828	49	PCDH9,MACF1,NCKAP5,ITPR2,ATP13A4,PARD3B,CTNND2,ERBB4,RYR3,ATP1A2
5.373e-03	-5.23	positive regulation of multicellular organismal process	biological process	GO:0051240	1691	11	18204	50	QKI,SOX5,ERBB4,RORA,CADM1,MACF1,SFXN5,NRXN1,ZBTB20,PTPRZ1,ATP1A2
5.382e-03	-5.22	SNTB2 (syntrophin beta 2)	protein interactions	6645	141	3	19454	49	DTNA,ERBB4,FGFR3
5.392e-03	-5.22	Distrobrevin	interpro domains	IPR017432	2	1	18521	50	DTNA
5.392e-03	-5.22	Nckap5l	interpro domains	IPR026163	2	1	18521	50	NCKAP5
5.392e-03	-5.22	Alpha_CARP_receptor-type	interpro domains	IPR041887	2	1	18521	50	PTPRZ1
5.392e-03	-5.22	NCKAP5_C	interpro domains	IPR032769	2	1	18521	50	NCKAP5
5.392e-03	-5.22	Ac_CoA_lig	interpro domains	IPR011904	2	1	18521	50	ACSS1
5.392e-03	-5.22	MSI_RRM2	interpro domains	IPR034126	2	1	18521	50	MSI2
5.392e-03	-5.22	Par3/HAL_N	interpro domains	IPR021922	2	1	18521	50	PARD3B
5.394e-03	-5.22	left_upper_lobe	COSMIC cancer mutations	left_upper_lobe	558	6	16828	49	RYR3,FBXL7,SLC4A4,TRPS1,ERBB4,CTNND2
5.440e-03	-5.21	sarcoplasmic reticulum membrane	cellular component	GO:0033017	43	2	19108	49	RYR3,ITPR2
5.461e-03	-5.21	central_nervous_system-brainstem-glioma-astrocytoma_Grade_I	COSMIC cancer mutations	central_nervous_system-brainstem-glioma-astrocytoma_Grade_I	38	2	16828	49	QKI,FGFR3
5.486e-03	-5.21	propionate biosynthetic process	biological process	GO:0019542	2	1	18204	50	ACSS1
5.486e-03	-5.21	myofibroblast contraction	biological process	GO:1990764	2	1	18204	50	QKI
5.486e-03	-5.21	negative regulation of 3'-UTR-mediated mRNA stabilization	biological process	GO:1905869	2	1	18204	50	QKI
5.486e-03	-5.21	establishment of planar polarity involved in nephron morphogenesis	biological process	GO:0072046	2	1	18204	50	ERBB4
5.486e-03	-5.21	fibroblast growth factor receptor apoptotic signaling pathway	biological process	GO:1902178	2	1	18204	50	FGFR3
5.486e-03	-5.21	regulation of elastin catabolic process	biological process	GO:0060310	2	1	18204	50	CST3
5.486e-03	-5.21	negative regulation of ERBB4 signaling pathway	biological process	GO:0120154	2	1	18204	50	CADM1
5.486e-03	-5.21	negative regulation of blood vessel remodeling	biological process	GO:0060313	2	1	18204	50	CST3
5.486e-03	-5.21	acetyl-CoA biosynthetic process from acetate	biological process	GO:0019427	2	1	18204	50	ACSS1
5.486e-03	-5.21	acetate biosynthetic process	biological process	GO:0019413	2	1	18204	50	ACSS1
5.601e-03	-5.18	sequence-specific double-stranded DNA binding	molecular function	GO:1990837	1547	10	18094	47	NPAS3,NFIA,RFX4,ZNF98,ZBTB20,HIF3A,TRPS1,ERBB4,RORA,SOX5
5.612e-03	-5.18	Par3_HAL_N_term	pfam domains	PF12053	2	1	17795	50	PARD3B
5.612e-03	-5.18	NCKAP5	pfam domains	PF15246	2	1	17795	50	NCKAP5
5.625e-03	-5.18	haematopoietic_and_lymphoid_tissue-lymph_node-lymphoid_neoplasm-diffuse_large_B_cell_lymphoma	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue-lymph_node-lymphoid_neoplasm-diffuse_large_B_cell_lymphoma	748	7	16828	49	TRPS1,CTNND2,ITPR2,SLC1A3,DTNA,ACSS1,SOX5
5.697e-03	-5.17	amino acid transport	biological process	GO:0006865	132	3	18204	50	SFXN5,SLC1A3,SLC1A2
5.706e-03	-5.17	Calml3 (calmodulin-like 3)	protein interactions	70405	144	3	19454	49	ABLIM1,ZBTB20,MACF1
5.718e-03	-5.16	active transmembrane transporter activity	molecular function	GO:0022804	444	5	18094	47	ATP1A2,ATP13A4,SLC1A3,SLC1A2,SLC4A4
5.767e-03	-5.16	sarcolemma	cellular component	GO:0042383	142	3	19108	49	RYR3,DTNA,ATP1A2
5.775e-03	-5.15	hand	COSMIC cancer mutations	hand	566	6	16828	49	HIF3A,SLC4A4,FGFR3,COL5A3,PREX2,ERBB4
5.817e-03	-5.15	regulation of sequestering of calcium ion	biological process	GO:0051282	133	3	18204	50	RYR3,ITPR2,ATP1A2
5.929e-03	-5.13	postsynapse	cellular component	GO:0098794	646	6	19108	49	TNIK,CTNND2,ATP1A2,GPM6A,CADM1,ERBB4
5.935e-03	-5.13	Vinculin, Vh2 four-helix bundle	gene3d domains	1.20.120.810	2	1	14470	43	CTNNA2
5.935e-03	-5.13	-	gene3d domains	6.20.350.10	2	1	14470	43	RYR3
5.944e-03	-5.13	breast-carcinoma-ductolobular_carcinoma	COSMIC cancer mutations	breast-carcinoma-ductolobular_carcinoma	1619	11	16828	49	FGFR3,MACF1,ABLIM1,RORA,DTNA,CDH20,PARD3B,PTPRZ1,CTNND2,QKI,PREX2
5.944e-03	-5.13	ductolobular_carcinoma	COSMIC cancer mutations	ductolobular_carcinoma	1619	11	16828	49	RORA,PTPRZ1,CTNND2,QKI,CDH20,PARD3B,FGFR3,ABLIM1,MACF1,PREX2,DTNA
6.035e-03	-5.11	Ig-like_dom	interpro domains	IPR007110	432	5	18521	50	FGFR3,CADM1,LRIG1,LSAMP,NTM
6.153e-03	-5.09	cell projection	cellular component	GO:0042995	2398	13	19108	49	ATP1A2,ABLIM1,AHCYL2,CTNNA2,CTNND2,GPM6A,DTNA,PCDH9,MACF1,SLC1A3,SLC1A2,CADM1,NRXN1
6.161e-03	-5.09	cell development	biological process	GO:0048468	2236	13	18204	50	NRXN1,CTNND2,CTNNA2,GPM6A,PTPRZ1,RORA,ERBB4,MSI2,SLC1A3,NTM,PREX2,QKI,TNIK
6.231e-03	-5.08	CATATPASE	prints domains	PR00119	35	2	5227	18	ATP1A2,ATP13A4
6.237e-03	-5.08	intracellular monoatomic cation homeostasis	biological process	GO:0030003	428	5	18204	50	SLC4A4,ATP13A4,SLC1A3,RYR3,ATP1A2
6.250e-03	-5.08	ZNRF2 (zinc and ring finger 2)	protein interactions	223082	47	2	19454	49	NCKAP5,ATP1A2
6.250e-03	-5.08	LRIG3 (leucine rich repeats and immunoglobulin like domains 3)	protein interactions	121227	47	2	19454	49	LRIG1,ERBB4
6.250e-03	-5.08	CNTN1 (contactin 1)	protein interactions	1272	47	2	19454	49	GPM6A,PTPRZ1
6.263e-03	-5.07	PAS domain	gene3d domains	3.30.450.20	40	2	14470	43	HIF3A,NPAS3
6.270e-03	-5.07	GSE1 (Gse1 coiled-coil protein)	protein interactions	23199	149	3	19454	49	SOX5,TNIK,NFIA
6.272e-03	-5.07	cell differentiation	biological process	GO:0030154	3645	18	18204	50	CADM1,ERBB4,RORA,PTPRZ1,GPM6A,FGFR3,CTNNA2,CTNND2,NRXN1,TNIK,QKI,NFIA,NHSL1,PREX2,NTM,SLC1A3,MSI2,SOX5
6.288e-03	-5.07	basal plasma membrane	cellular component	GO:0009925	288	4	19108	49	ERBB4,SLC4A4,CADM1,SLC1A3
6.328e-03	-5.06	cellular developmental process	biological process	GO:0048869	3648	18	18204	50	NFIA,QKI,TNIK,SOX5,MSI2,NTM,SLC1A3,PREX2,NHSL1,RORA,ERBB4,CADM1,NRXN1,CTNND2,FGFR3,CTNNA2,PTPRZ1,GPM6A
6.428e-03	-5.05	skin-hand-carcinoma-squamous_cell_carcinoma	COSMIC cancer mutations	skin-hand-carcinoma-squamous_cell_carcinoma	407	5	16828	49	ERBB4,COL5A3,FGFR3,HIF3A,SLC4A4
6.429e-03	-5.05	extremity	COSMIC cancer mutations	extremity	1876	12	16828	49	FBXL7,RYR3,PREX2,CDH20,PITPNC1,PTPRZ1,ERBB4,ACSS1,COL5A3,PCDH9,FGFR3,ATP13A4
6.454e-03	-5.04	leg	COSMIC cancer mutations	leg	969	8	16828	49	FGFR3,ATP13A4,PTPRZ1,HIF3A,SLC4A4,NTM,ZBTB20,COL5A3
6.466e-03	-5.04	carboxylic acid biosynthetic process	biological process	GO:0046394	271	4	18204	50	SLC1A3,QKI,PTGDS,ACSS1
6.576e-03	-5.02	SP7 (Sp7 transcription factor)	protein interactions	121340	297	4	19454	49	SOX5,TRPS1,NFIA,QKI
6.597e-03	-5.02	upper_arm	COSMIC cancer mutations	upper_arm	582	6	16828	49	ITPR2,FGFR3,PARD3B,ERBB4,SLC4A4,PREX2
6.634e-03	-5.02	vascular process in circulatory system	biological process	GO:0003018	273	4	18204	50	SLC1A2,SLC1A3,SLC4A4,ATP1A2
6.676e-03	-5.01	inorganic cation transmembrane transport	biological process	GO:0098662	618	6	18204	50	SLC4A4,RYR3,ITPR2,SLC1A3,ATP1A2,GPM6A
6.684e-03	-5.01	symporter activity	molecular function	GO:0015293	148	3	18094	47	SLC1A3,SLC4A4,SLC1A2
6.719e-03	-5.00	organic acid biosynthetic process	biological process	GO:0016053	274	4	18204	50	ACSS1,PTGDS,SLC1A3,QKI
6.728e-03	-5.00	behavior	biological process	GO:0007610	619	6	18204	50	PREX2,PTPRZ1,ATP1A2,NRXN1,SLC1A2,SLC1A3
6.745e-03	-5.00	SOX6 (SRY-box transcription factor 6)	protein interactions	55553	153	3	19454	49	NFIA,TRPS1,SOX5
6.760e-03	-5.00	peritoneum-appendix-other-pseudomyxoma_peritonei	COSMIC cancer mutations	peritoneum-appendix-other-pseudomyxoma_peritonei	585	6	16828	49	COL5A3,TRPS1,NCKAP5,MACF1,FBXL7,FGFR3
6.760e-03	-5.00	pseudomyxoma_peritonei	COSMIC cancer mutations	pseudomyxoma_peritonei	585	6	16828	49	NCKAP5,MACF1,FBXL7,FGFR3,COL5A3,TRPS1
6.783e-03	-4.99	ATPASE_E1_E2	prosite domains	PS00154	36	2	12186	42	ATP13A4,ATP1A2
6.788e-03	-4.99	acidic amino acid transport	biological process	GO:0015800	45	2	18204	50	SLC1A3,SLC1A2
6.798e-03	-4.99	intracellular monoatomic ion homeostasis	biological process	GO:0006873	437	5	18204	50	ATP1A2,SLC1A3,SLC4A4,ATP13A4,RYR3
6.815e-03	-4.99	appendix	COSMIC cancer mutations	appendix	586	6	16828	49	COL5A3,FBXL7,TRPS1,NCKAP5,MACF1,FGFR3
6.870e-03	-4.98	peritoneum	COSMIC cancer mutations	peritoneum	587	6	16828	49	TRPS1,FGFR3,NCKAP5,MACF1,COL5A3,FBXL7
6.875e-03	-4.98	transmembrane transport	biological process	GO:0055085	1264	9	18204	50	ATP1A2,GPM6A,SFXN5,SLC1A3,SLC1A2,ITPR2,RYR3,ATP13A4,SLC4A4
6.890e-03	-4.98	telencephalon development	biological process	GO:0021537	276	4	18204	50	ATP1A2,RFX4,ERBB4,SLC1A2
6.969e-03	-4.97	monoatomic anion transmembrane transport	biological process	GO:0098656	142	3	18204	50	SLC4A4,SLC1A3,SLC1A2
7.084e-03	-4.95	positive regulation of glial cell differentiation	biological process	GO:0045687	46	2	18204	50	PTPRZ1,QKI
7.084e-03	-4.95	regulation of oligodendrocyte differentiation	biological process	GO:0048713	46	2	18204	50	PTPRZ1,QKI
7.130e-03	-4.94	CARM1 (coactivator associated arginine methyltransferase 1)	protein interactions	10498	304	4	19454	49	NCKAP5,RORA,QKI,DTNA
7.312e-03	-4.92	metal ion transport	biological process	GO:0030001	630	6	18204	50	ITPR2,SLC4A4,RYR3,GPM6A,ATP1A2,SLC1A3
7.325e-03	-4.92	Ndc80 (NDC80 kinetochore complex component)	protein interactions	67052	51	2	19454	49	MACF1,NHSL1
7.349e-03	-4.91	DNA-binding transcription factor activity, RNA polymerase II-specific	molecular function	GO:0000981	1355	9	18094	47	ZNF98,ZBTB20,NPAS3,NFIA,RFX4,TRPS1,HIF3A,SOX5,RORA
7.493e-03	-4.89	cell surface	cellular component	GO:0009986	896	7	19108	49	NRXN1,GPC5,SLC1A2,FGFR3,SLC1A3,SLC4A4,ATP1A2
7.538e-03	-4.89	QRFPR (pyroglutamylated RFamide peptide receptor)	protein interactions	84109	3	1	19454	49	NTM
7.538e-03	-4.89	TULP1 (TUB like protein 1)	protein interactions	7287	3	1	19454	49	NRXN1
7.538e-03	-4.89	Hk2 (hexokinase 2)	protein interactions	25059	3	1	19454	49	PTGDS
7.538e-03	-4.89	BCO1 (beta-carotene oxygenase 1)	protein interactions	53630	3	1	19454	49	ABLIM1
7.538e-03	-4.89	IL34 (interleukin 34)	protein interactions	146433	3	1	19454	49	PTPRZ1
7.538e-03	-4.89	NRG3 (neuregulin 3)	protein interactions	10718	3	1	19454	49	ERBB4
7.592e-03	-4.88	third_ventricle	COSMIC cancer mutations	third_ventricle	45	2	16828	49	FGFR3,QKI
7.605e-03	-4.88	SNAP91 (synaptosome associated protein 91)	protein interactions	9892	52	2	19454	49	ERBB4,GPM6A
7.626e-03	-4.88	SOX5 (SRY-box transcription factor 5)	protein interactions	6660	160	3	19454	49	TRPS1,SOX5,NFIA
7.631e-03	-4.88	human chr8q23.3	chromosome location	human chr8q23.3	4	1	26134	50	TRPS1
7.700e-03	-4.87	cell junction assembly	biological process	GO:0034329	285	4	18204	50	ERBB4,NRXN1,GPM6A,CDH20
7.700e-03	-4.87	astrocytoma_Grade_I	COSMIC cancer mutations	astrocytoma_Grade_I	139	3	16828	49	QKI,FGFR3,GPC5
7.702e-03	-4.87	animal organ development	biological process	GO:0048513	2846	15	18204	50	SLC1A2,COL5A3,CTNNA2,FGFR3,GPM6A,ATP1A2,RORA,ERBB4,CADM1,PCDH9,ABLIM1,SOX5,RFX4,NFIA,LRIG1
7.761e-03	-4.86	C20 prostanoid biosynthesis	BIOCYC pathways	HUMAN_PWY66-374	7	1	902	1	PTGDS
7.761e-03	-4.86	C20 prostanoid biosynthesis	BIOCYC pathways	META_PWY66-374	7	1	902	1	PTGDS
7.773e-03	-4.86	epidermal growth factor receptor activity	molecular function	GO:0005006	3	1	18094	47	ERBB4
7.773e-03	-4.86	neuregulin receptor activity	molecular function	GO:0038131	3	1	18094	47	ERBB4
7.773e-03	-4.86	prostaglandin-D synthase activity	molecular function	GO:0004667	3	1	18094	47	PTGDS
7.773e-03	-4.86	adenosylhomocysteinase activity	molecular function	GO:0004013	3	1	18094	47	AHCYL2
7.773e-03	-4.86	hydrolase activity, acting on carbon-sulfur bonds	molecular function	GO:0046508	3	1	18094	47	AHCYL2
7.773e-03	-4.86	cysteine transmembrane transporter activity	molecular function	GO:0033229	3	1	18094	47	SLC1A2
7.773e-03	-4.86	inositol 1,4,5-trisphosphate-gated calcium channel activity	molecular function	GO:0005220	3	1	18094	47	ITPR2
7.800e-03	-4.85	abdomen	COSMIC cancer mutations	abdomen	603	6	16828	49	CTNND2,PREX2,ERBB4,ITPR2,LRIG1,FGFR3
7.832e-03	-4.85	response to organic cyclic compound	biological process	GO:0014070	843	7	18204	50	SLC1A2,SLC1A3,ATP1A2,RORA,RYR3,PTGDS,ITPR2
7.847e-03	-4.85	basal part of cell	cellular component	GO:0045178	307	4	19108	49	SLC1A3,ERBB4,CADM1,SLC4A4
7.891e-03	-4.84	FOXF2 (forkhead box F2)	protein interactions	2295	53	2	19454	49	AHCYL2,ZBTB20
7.952e-03	-4.83	neuromuscular process	biological process	GO:0050905	149	3	18204	50	SLC1A3,NRXN1,CTNNA2
7.964e-03	-4.83	Cardiac conduction	REACTOME pathways	R-HSA-5576891	142	3	10285	30	ITPR2,RYR3,ATP1A2
8.078e-03	-4.82	MAML1-3	interpro domains	IPR046369	3	1	18521	50	MAML2
8.078e-03	-4.82	Mastermind-like_N	interpro domains	IPR019082	3	1	18521	50	MAML2
8.078e-03	-4.82	RYDR_Jsol	interpro domains	IPR048581	3	1	18521	50	RYR3
8.078e-03	-4.82	S-Ado-L-homoCys_hydrolase_CS	interpro domains	IPR020082	3	1	18521	50	AHCYL2
8.078e-03	-4.82	InsP3_rcpt	interpro domains	IPR000493	3	1	18521	50	ITPR2
8.078e-03	-4.82	ROR_rcpt	interpro domains	IPR003079	3	1	18521	50	RORA
8.078e-03	-4.82	Ryanodine_rcpt	interpro domains	IPR003032	3	1	18521	50	RYR3
8.078e-03	-4.82	Adenosylhomocysteinase-like	interpro domains	IPR000043	3	1	18521	50	AHCYL2
8.078e-03	-4.82	SPRY1_RyR	interpro domains	IPR035761	3	1	18521	50	RYR3
8.078e-03	-4.82	Myelin_PLP_CS	interpro domains	IPR018237	3	1	18521	50	GPM6A
8.078e-03	-4.82	HIF_alpha-like	interpro domains	IPR021537	3	1	18521	50	HIF3A
8.078e-03	-4.82	NR_DBD_ROR	interpro domains	IPR044101	3	1	18521	50	RORA
8.078e-03	-4.82	Ado_hCys_hydrolase_NAD-bd	interpro domains	IPR015878	3	1	18521	50	AHCYL2
8.078e-03	-4.82	SPRY3_RyR	interpro domains	IPR035762	3	1	18521	50	RYR3
8.078e-03	-4.82	Vinculin_CS	interpro domains	IPR000633	3	1	18521	50	CTNNA2
8.078e-03	-4.82	MAML_N_sf	interpro domains	IPR046370	3	1	18521	50	MAML2
8.078e-03	-4.82	Ryanrecept_TM4-6	interpro domains	IPR009460	3	1	18521	50	RYR3
8.078e-03	-4.82	Adenosylhomocyst_ase-like_sf	interpro domains	IPR042172	3	1	18521	50	AHCYL2
8.078e-03	-4.82	TM_ErbB1	interpro domains	IPR049328	3	1	18521	50	ERBB4
8.078e-03	-4.82	Myelin_PLP	interpro domains	IPR001614	3	1	18521	50	GPM6A
8.078e-03	-4.82	Ryan_recept	interpro domains	IPR013333	3	1	18521	50	RYR3
8.078e-03	-4.82	SPRY2_RyR	interpro domains	IPR035764	3	1	18521	50	RYR3
8.124e-03	-4.81	neuronal cell body	cellular component	GO:0043025	489	5	19108	49	NRXN1,ATP1A2,GPM6A,SLC1A3,CTNND2
8.157e-03	-4.81	oesophagus-middle_third-carcinoma-squamous_cell_carcinoma	COSMIC cancer mutations	oesophagus-middle_third-carcinoma-squamous_cell_carcinoma	3531	18	16828	49	TNIK,PREX2,NHSL1,SLC4A4,SOX5,MAML2,RYR3,CTNND2,PTPRZ1,ATP1A2,COL5A3,ZBTB20,LRIG1,GPC5,GPM6A,MACF1,PCDH9,ABLIM1
8.181e-03	-4.81	SYNM (synemin)	protein interactions	23336	54	2	19454	49	ERBB4,DTNA
8.206e-03	-4.80	middle_third	COSMIC cancer mutations	middle_third	3533	18	16828	49	CTNND2,PTPRZ1,TNIK,PREX2,SOX5,SLC4A4,NHSL1,MAML2,RYR3,GPM6A,PCDH9,ABLIM1,MACF1,COL5A3,ATP1A2,ZBTB20,GPC5,LRIG1
8.218e-03	-4.80	regulation of calcium:sodium antiporter activity	biological process	GO:1903279	3	1	18204	50	ATP1A2
8.218e-03	-4.80	acetate metabolic process	biological process	GO:0006083	3	1	18204	50	ACSS1
8.218e-03	-4.80	central nervous system morphogenesis	biological process	GO:0021551	3	1	18204	50	ERBB4
8.218e-03	-4.80	radial glia guided migration of Purkinje cell	biological process	GO:0021942	3	1	18204	50	CTNNA2
8.218e-03	-4.80	cysteine transport	biological process	GO:0042883	3	1	18204	50	SLC1A2
8.218e-03	-4.80	cysteine transmembrane transport	biological process	GO:1903712	3	1	18204	50	SLC1A2
8.218e-03	-4.80	neuroligin clustering involved in postsynaptic membrane assembly	biological process	GO:0097118	3	1	18204	50	NRXN1
8.218e-03	-4.80	susceptibility to natural killer cell mediated cytotoxicity	biological process	GO:0042271	3	1	18204	50	CADM1
8.296e-03	-4.79	EGR2 (early growth response 2)	protein interactions	1959	165	3	19454	49	SOX5,TRPS1,NFIA
8.310e-03	-4.79	HNRNPL (heterogeneous nuclear ribonucleoprotein L)	protein interactions	3191	1958	11	19454	49	FGFR3,TRPS1,MACF1,NFIA,AHCYL2,PARD3B,MSI2,ABLIM1,ZBTB20,QKI,DTNA
8.327e-03	-4.79	cell surface receptor signaling pathway via JAK-STAT	biological process	GO:0007259	50	2	18204	50	FGFR3,ERBB4
8.365e-03	-4.78	ATPase-coupled monoatomic cation transmembrane transporter activity	molecular function	GO:0019829	53	2	18094	47	ATP13A4,ATP1A2
8.406e-03	-4.78	HIF-1	pfam domains	PF11413	3	1	17795	50	HIF3A
8.406e-03	-4.78	TM_ErbB1	pfam domains	PF21314	3	1	17795	50	ERBB4
8.406e-03	-4.78	AdoHcyase	pfam domains	PF05221	3	1	17795	50	AHCYL2
8.406e-03	-4.78	AdoHcyase_NAD	pfam domains	PF00670	3	1	17795	50	AHCYL2
8.406e-03	-4.78	MamL-1	pfam domains	PF09596	3	1	17795	50	MAML2
8.406e-03	-4.78	RR_TM4-6	pfam domains	PF06459	3	1	17795	50	RYR3
8.406e-03	-4.78	SR_plectin_7	pfam domains	PF21097	3	1	17795	50	MACF1
8.406e-03	-4.78	RYDR_Jsol	pfam domains	PF21119	3	1	17795	50	RYR3
8.406e-03	-4.78	RyR	pfam domains	PF02026	3	1	17795	50	RYR3
8.406e-03	-4.78	Myelin_PLP	pfam domains	PF01275	3	1	17795	50	GPM6A
8.444e-03	-4.77	RNA polymerase II transcription regulatory region sequence-specific DNA binding	molecular function	GO:0000977	1385	9	18094	47	RORA,SOX5,TRPS1,HIF3A,ZNF98,ZBTB20,NFIA,NPAS3,RFX4
8.494e-03	-4.77	double-stranded DNA binding	molecular function	GO:0003690	1643	10	18094	47	SOX5,RORA,ERBB4,TRPS1,HIF3A,ZBTB20,ZNF98,NPAS3,RFX4,NFIA
8.546e-03	-4.76	acute_lymphoblastic_leukaemia	COSMIC cancer mutations	acute_lymphoblastic_leukaemia	2197	13	16828	49	SLC4A4,SOX5,PREX2,TNIK,PARD3B,CADM1,TRPS1,NFIA,PTPRZ1,ERBB4,DTNA,ATP1A2,FGFR3
8.651e-03	-4.75	neuromuscular process controlling balance	biological process	GO:0050885	51	2	18204	50	NRXN1,SLC1A3
8.702e-03	-4.74	calcium-mediated signaling	biological process	GO:0019722	154	3	18204	50	RYR3,ITPR2,ATP1A2
8.711e-03	-4.74	lentigo	COSMIC cancer mutations	lentigo	3	1	16828	49	FGFR3
8.711e-03	-4.74	skin-face-lentigo	COSMIC cancer mutations	skin-face-lentigo	3	1	16828	49	FGFR3
8.711e-03	-4.74	skin-leg-lentigo	COSMIC cancer mutations	skin-leg-lentigo	3	1	16828	49	FGFR3
8.711e-03	-4.74	skin-forearm-lentigo	COSMIC cancer mutations	skin-forearm-lentigo	3	1	16828	49	FGFR3
8.711e-03	-4.74	skin-lentigo	COSMIC cancer mutations	skin-lentigo	3	1	16828	49	FGFR3
8.711e-03	-4.74	skin-trunk-other-seborrhoeic_keratosis	COSMIC cancer mutations	skin-trunk-other-seborrhoeic_keratosis	3	1	16828	49	FGFR3
8.711e-03	-4.74	skin-trunk-lentigo	COSMIC cancer mutations	skin-trunk-lentigo	3	1	16828	49	FGFR3
8.711e-03	-4.74	skin-hand-lentigo	COSMIC cancer mutations	skin-hand-lentigo	3	1	16828	49	FGFR3
8.711e-03	-4.74	skin-leg-other-seborrhoeic_keratosis	COSMIC cancer mutations	skin-leg-other-seborrhoeic_keratosis	3	1	16828	49	FGFR3
8.711e-03	-4.74	urinary_tract-bladder-papilloma	COSMIC cancer mutations	urinary_tract-bladder-papilloma	3	1	16828	49	FGFR3
8.736e-03	-4.74	Amyotrophic lateral sclerosis (ALS)	WikiPathways	WP2447	38	2	5310	20	CST3,SLC1A2
8.761e-03	-4.74	postsynaptic density	cellular component	GO:0014069	317	4	19108	49	CTNND2,TNIK,ERBB4,CADM1
8.771e-03	-4.74	positive regulation of nervous system development	biological process	GO:0051962	296	4	18204	50	QKI,MACF1,NRXN1,PTPRZ1
8.816e-03	-4.73	sequence-specific DNA binding	molecular function	GO:0043565	1652	10	18094	47	ERBB4,RORA,SOX5,ZNF98,ZBTB20,RFX4,NPAS3,NFIA,TRPS1,HIF3A
8.836e-03	-4.73	skin-back-malignant_melanoma	COSMIC cancer mutations	skin-back-malignant_melanoma	280	4	16828	49	ATP1A2,ERBB4,TNIK,PREX2
8.889e-03	-4.72	-	gene3d domains	6.10.250.2510	3	1	14470	43	CTNNA2
8.889e-03	-4.72	-	gene3d domains	6.10.250.970	3	1	14470	43	MAML2
8.889e-03	-4.72	-	gene3d domains	1.10.490.160	3	1	14470	43	RYR3
8.889e-03	-4.72	Adenosylhomocysteinase-like	gene3d domains	3.40.50.1480	3	1	14470	43	AHCYL2
8.972e-03	-4.71	chest	COSMIC cancer mutations	chest	147	3	16828	49	PREX2,ERBB4,FGFR3
8.982e-03	-4.71	regulation of purine nucleotide catabolic process	biological process	GO:0033121	52	2	18204	50	ZBTB20,SLC4A4
8.982e-03	-4.71	regulation of nucleotide catabolic process	biological process	GO:0030811	52	2	18204	50	ZBTB20,SLC4A4
8.982e-03	-4.71	regulation of glycolytic process	biological process	GO:0006110	52	2	18204	50	SLC4A4,ZBTB20
9.081e-03	-4.70	NXPH3 (neurexophilin 3)	protein interactions	11248	57	2	19454	49	CTNNA2,NRXN1
9.185e-03	-4.69	SLC-mediated transmembrane transport	REACTOME pathways	R-HSA-425407	287	4	10285	30	AHCYL2,SLC1A2,SLC1A3,SLC4A4
9.273e-03	-4.68	NR3C1 (nuclear receptor subfamily 3 group C member 1)	protein interactions	2908	950	7	19454	49	ZBTB20,CADM1,CTNND2,TRPS1,ATP13A4,NFIA,SLC1A3
9.318e-03	-4.68	neutral amino acid transport	biological process	GO:0015804	53	2	18204	50	SLC1A3,SLC1A2
9.318e-03	-4.68	regulation of chondrocyte differentiation	biological process	GO:0032330	53	2	18204	50	SOX5,TRPS1
9.428e-03	-4.66	upper_aerodigestive_tract-pharynx-carcinoma-squamous_cell_carcinoma	COSMIC cancer mutations	upper_aerodigestive_tract-pharynx-carcinoma-squamous_cell_carcinoma	1485	10	16828	49	PREX2,DTNA,RYR3,GPC5,PTPRZ1,NPAS3,FGFR3,PARD3B,MACF1,PCDH9
9.492e-03	-4.66	monoatomic anion transport	biological process	GO:0006820	159	3	18204	50	SLC1A2,SLC1A3,SLC4A4
9.541e-03	-4.65	Ig-like_dom_sf	interpro domains	IPR036179	483	5	18521	50	LRIG1,LSAMP,NTM,FGFR3,CADM1
9.597e-03	-4.65	Neurotransmitter Release Cycle	REACTOME pathways	R-HSA-112310	51	2	10285	30	SLC1A3,SLC1A2
9.616e-03	-4.64	lung-carcinoma-squamous_cell_carcinoma	COSMIC cancer mutations	lung-carcinoma-squamous_cell_carcinoma	14664	48	16828	49	RORA,PTGDS,ABLIM1,NKAIN3,COL5A3,GPC5,SFXN5,TRPS1,SOX5,MSI2,RFX4,FGFR3,ATP13A4,NCKAP5,ACSS1,NPAS3,ERBB4,AHCYL2,CTNND2,QKI,SLC1A2,PARD3B,NRXN1,PREX2,MAML2,GPM6A,LSAMP,ITPR2,PCDH9,MACF1,PTPRZ1,NFIA,ZNF98,PITPNC1,CDH20,TNIK,FBXL7,HIF3A,ZBTB20,DTNA,SLC1A3,ATP1A2,LRIG1,NTM,CADM1,RYR3,NHSL1,SLC4A4
9.659e-03	-4.64	cell surface receptor signaling pathway via STAT	biological process	GO:0097696	54	2	18204	50	ERBB4,FGFR3
9.736e-03	-4.63	LHX3 (LIM homeobox 3)	protein interactions	8022	175	3	19454	49	TRPS1,SOX5,NFIA
1.001e-02	-4.60	response to cocaine	biological process	GO:0042220	55	2	18204	50	SLC1A2,SLC1A3
1.002e-02	-4.60	SNTB1 (syntrophin beta 1)	protein interactions	6641	60	2	19454	49	DTNA,FGFR3
1.002e-02	-4.60	Znf_NHR/GATA	interpro domains	IPR013088	56	2	18521	50	RORA,TRPS1
1.004e-02	-4.60	Nme2 (NME/NM23 nucleoside diphosphate kinase 2)	protein interactions	18103	4	1	19454	49	RORA
1.004e-02	-4.60	Ctbp2 (C-terminal binding protein 2)	protein interactions	13017	4	1	19454	49	TRPS1
1.004e-02	-4.60	CCDC126 (coiled-coil domain containing 126)	protein interactions	90693	4	1	19454	49	GPM6A
1.004e-02	-4.60	GATA3 (GATA binding protein 3)	protein interactions	2625	177	3	19454	49	TRPS1,QKI,NFIA
1.016e-02	-4.59	EZR (ezrin)	protein interactions	7430	526	5	19454	49	DTNA,AHCYL2,TNIK,ABLIM1,MACF1
1.022e-02	-4.58	extrinsic component of membrane	cellular component	GO:0019898	175	3	19108	49	CTNNA2,DTNA,CDH20
1.022e-02	-4.58	collagen type V trimer	cellular component	GO:0005588	4	1	19108	49	COL5A3
1.030e-02	-4.58	RYANODINER	prints domains	PR00795	3	1	5227	18	RYR3
1.030e-02	-4.58	PGNDSYNTHASE	prints domains	PR01254	3	1	5227	18	PTGDS
1.030e-02	-4.58	MYELINPLP	prints domains	PR00214	3	1	5227	18	GPM6A
1.030e-02	-4.58	RORNUCRECPTR	prints domains	PR01293	3	1	5227	18	RORA
1.030e-02	-4.58	INSP3RECEPTR	prints domains	PR00779	3	1	5227	18	ITPR2
1.030e-02	-4.58	MYELIN_PLP_2	prosite domains	PS01004	3	1	12186	42	GPM6A
1.030e-02	-4.58	ADOHCYASE_2	prosite domains	PS00739	3	1	12186	42	AHCYL2
1.030e-02	-4.58	VINCULIN_1	prosite domains	PS00663	3	1	12186	42	CTNNA2
1.030e-02	-4.58	ADOHCYASE_1	prosite domains	PS00738	3	1	12186	42	AHCYL2
1.030e-02	-4.58	MYELIN_PLP_1	prosite domains	PS00575	3	1	12186	42	GPM6A
1.035e-02	-4.57	propionate-CoA ligase activity	molecular function	GO:0050218	4	1	18094	47	ACSS1
1.035e-02	-4.57	tricarboxylic acid transmembrane transporter activity	molecular function	GO:0015142	4	1	18094	47	SFXN5
1.035e-02	-4.57	ryanodine-sensitive calcium-release channel activity	molecular function	GO:0005219	4	1	18094	47	RYR3
1.035e-02	-4.57	citrate transmembrane transporter activity	molecular function	GO:0015137	4	1	18094	47	SFXN5
1.035e-02	-4.57	short-chain fatty acid-CoA ligase activity	molecular function	GO:0031955	4	1	18094	47	ACSS1
1.035e-02	-4.57	acetate-CoA ligase activity	molecular function	GO:0003987	4	1	18094	47	ACSS1
1.036e-02	-4.57	release of sequestered calcium ion into cytosol	biological process	GO:0051209	56	2	18204	50	ITPR2,RYR3
1.036e-02	-4.57	asymmetric synapse	cellular component	GO:0032279	333	4	19108	49	CADM1,ERBB4,TNIK,CTNND2
1.049e-02	-4.56	monocarboxylic acid biosynthetic process	biological process	GO:0072330	165	3	18204	50	QKI,ACSS1,PTGDS
1.049e-02	-4.56	import across plasma membrane	biological process	GO:0098739	165	3	18204	50	ATP1A2,SLC1A3,SLC1A2
1.049e-02	-4.56	homophilic cell adhesion via plasma membrane adhesion molecules	biological process	GO:0007156	165	3	18204	50	CDH20,CADM1,PCDH9
1.051e-02	-4.56	MYOD1 (myogenic differentiation 1)	protein interactions	4654	180	3	19454	49	TRPS1,NFIA,RORA
1.051e-02	-4.56	EPHA4 (EPH receptor A4)	protein interactions	2043	180	3	19454	49	FGFR3,CTNNA2,AHCYL2
1.072e-02	-4.54	visual behavior	biological process	GO:0007632	57	2	18204	50	ATP1A2,SLC1A2
1.072e-02	-4.54	negative regulation of sequestering of calcium ion	biological process	GO:0051283	57	2	18204	50	ITPR2,RYR3
1.076e-02	-4.53	CTF/NFI_DNA-bd_N	interpro domains	IPR019548	4	1	18521	50	NFIA
1.076e-02	-4.53	PCN-like_spectrin-like_rpt	interpro domains	IPR049538	4	1	18521	50	MACF1
1.076e-02	-4.53	FGF_rcpt_fam	interpro domains	IPR016248	4	1	18521	50	FGFR3
1.076e-02	-4.53	ACAS_N	interpro domains	IPR032387	4	1	18521	50	ACSS1
1.076e-02	-4.53	P5B-type_ATPase	interpro domains	IPR047821	4	1	18521	50	ATP13A4
1.076e-02	-4.53	CTF/NFI_DNA-bd-dom	interpro domains	IPR020604	4	1	18521	50	NFIA
1.076e-02	-4.53	Desmoplakin_Spectrin-like	interpro domains	IPR041573	4	1	18521	50	MACF1
1.076e-02	-4.53	P5A-ATPase_N	interpro domains	IPR047819	4	1	18521	50	ATP13A4
1.076e-02	-4.53	CTF/NFI	interpro domains	IPR000647	4	1	18521	50	NFIA
1.076e-02	-4.53	CTF/NFI_DNA-bd_CS	interpro domains	IPR019739	4	1	18521	50	NFIA
1.076e-02	-4.53	AbLIM_anchor	interpro domains	IPR032402	4	1	18521	50	ABLIM1
1.076e-02	-4.53	Na/K-Atpase_Interacting	interpro domains	IPR008516	4	1	18521	50	NKAIN3
1.076e-02	-4.53	NHS-like	interpro domains	IPR024845	4	1	18521	50	NHSL1
1.076e-02	-4.53	Tyr_kinase_EGF/ERB/XmrK_rcpt	interpro domains	IPR016245	4	1	18521	50	ERBB4
1.076e-02	-4.53	Alpha_catenin	interpro domains	IPR001033	4	1	18521	50	CTNNA2
1.082e-02	-4.53	DNA-binding transcription factor activity	molecular function	GO:0003700	1441	9	18094	47	HIF3A,TRPS1,RFX4,NPAS3,NFIA,ZBTB20,ZNF98,RORA,SOX5
1.094e-02	-4.52	negative regulation of male germ cell proliferation	biological process	GO:2000255	4	1	18204	50	PTGDS
1.094e-02	-4.52	short-chain fatty acid biosynthetic process	biological process	GO:0051790	4	1	18204	50	ACSS1
1.094e-02	-4.52	regulation of glutamate uptake involved in transmission of nerve impulse	biological process	GO:0051946	4	1	18204	50	ATP1A2
1.094e-02	-4.52	positive regulation of mesenchymal stem cell differentiation	biological process	GO:2000741	4	1	18204	50	SOX5
1.094e-02	-4.52	regulation of collagen catabolic process	biological process	GO:0010710	4	1	18204	50	CST3
1.094e-02	-4.52	regulation of amino acid uptake involved in synaptic transmission	biological process	GO:0051941	4	1	18204	50	ATP1A2
1.094e-02	-4.52	negative regulation of germ cell proliferation	biological process	GO:1905937	4	1	18204	50	PTGDS
1.094e-02	-4.52	cardiac muscle tissue regeneration	biological process	GO:0061026	4	1	18204	50	ERBB4
1.094e-02	-4.52	response to glycoside	biological process	GO:1903416	4	1	18204	50	ATP1A2
1.098e-02	-4.51	primitive_neuroectodermal_tumour-medulloblastoma	COSMIC cancer mutations	primitive_neuroectodermal_tumour-medulloblastoma	15350	49	16828	49	PARD3B,NRXN1,ERBB4,NPAS3,SLC1A2,QKI,AHCYL2,CTNND2,MAML2,PREX2,ATP13A4,FGFR3,NCKAP5,MSI2,CST3,RFX4,ACSS1,TRPS1,SOX5,PTGDS,ABLIM1,RORA,GPC5,SFXN5,NKAIN3,COL5A3,CADM1,RYR3,SLC4A4,NHSL1,LRIG1,NTM,ZBTB20,ATP1A2,DTNA,SLC1A3,CDH20,NFIA,PTPRZ1,PITPNC1,ZNF98,FBXL7,HIF3A,TNIK,PCDH9,MACF1,ITPR2,LSAMP,GPM6A
1.101e-02	-4.51	cadherin binding	molecular function	GO:0045296	335	4	18094	47	MACF1,CTNNA2,CTNND2,CDH20
1.103e-02	-4.51	skin-upper_leg-malignant_melanoma	COSMIC cancer mutations	skin-upper_leg-malignant_melanoma	850	7	16828	49	NFIA,ERBB4,PCDH9,PREX2,ACSS1,LRIG1,HIF3A
1.110e-02	-4.50	cellular homeostasis	biological process	GO:0019725	689	6	18204	50	RYR3,SLC1A3,ATP13A4,SLC4A4,ATP1A2,ZBTB20
1.111e-02	-4.50	plasma membrane bounded cell projection	cellular component	GO:0120025	2285	12	19108	49	AHCYL2,CTNNA2,ABLIM1,ATP1A2,CADM1,SLC1A3,MACF1,PCDH9,SLC1A2,CTNND2,GPM6A,DTNA
1.118e-02	-4.49	parathyroid-carcinoma	COSMIC cancer mutations	parathyroid-carcinoma	300	4	16828	49	MACF1,RYR3,GPC5,TRPS1
1.118e-02	-4.49	parietal_lobe	COSMIC cancer mutations	parietal_lobe	55	2	16828	49	QKI,FGFR3
1.119e-02	-4.49	P5-ATPase	pfam domains	PF12409	4	1	17795	50	ATP13A4
1.119e-02	-4.49	Spectrin_3	pfam domains	PF21019	4	1	17795	50	MACF1
1.119e-02	-4.49	NHS	pfam domains	PF15273	4	1	17795	50	NHSL1
1.119e-02	-4.49	CTF_NFI	pfam domains	PF00859	4	1	17795	50	NFIA
1.119e-02	-4.49	Spectrin_4	pfam domains	PF21020	4	1	17795	50	MACF1
1.119e-02	-4.49	Spectrin_2	pfam domains	PF18373	4	1	17795	50	MACF1
1.119e-02	-4.49	AbLIM_anchor	pfam domains	PF16182	4	1	17795	50	ABLIM1
1.119e-02	-4.49	NKAIN	pfam domains	PF05640	4	1	17795	50	NKAIN3
1.119e-02	-4.49	NfI_DNAbd_pre-N	pfam domains	PF10524	4	1	17795	50	NFIA
1.119e-02	-4.49	ACAS_N	pfam domains	PF16177	4	1	17795	50	ACSS1
1.131e-02	-4.48	transmembrane receptor protein tyrosine kinase activity	molecular function	GO:0004714	62	2	18094	47	FGFR3,ERBB4
1.134e-02	-4.48	VSX1 (visual system homeobox 1)	protein interactions	30813	64	2	19454	49	TRPS1,NFIA
1.134e-02	-4.48	SYNC (syncoilin, intermediate filament protein)	protein interactions	81493	64	2	19454	49	DTNA,MAML2
1.138e-02	-4.48	MamL-1	smart domains	SM01275	3	1	9717	37	MAML2
1.138e-02	-4.48	PLP	smart domains	SM00002	3	1	9717	37	GPM6A
1.138e-02	-4.48	AdoHcyase	smart domains	SM00996	3	1	9717	37	AHCYL2
1.138e-02	-4.48	AdoHcyase_NAD	smart domains	SM00997	3	1	9717	37	AHCYL2
1.143e-02	-4.47	human chr14q13.1	chromosome location	human chr14q13.1	6	1	26134	50	NPAS3
1.143e-02	-4.47	human chr4q34.2	chromosome location	human chr4q34.2	6	1	26134	50	GPM6A
1.145e-02	-4.47	protein localization to synapse	biological process	GO:0035418	59	2	18204	50	ERBB4,NRXN1
1.160e-02	-4.46	skin-benign_melanocytic_nevus-junctional	COSMIC cancer mutations	skin-benign_melanocytic_nevus-junctional	4	1	16828	49	FGFR3
1.160e-02	-4.46	urinary_tract-bladder-other-normal	COSMIC cancer mutations	urinary_tract-bladder-other-normal	4	1	16828	49	FGFR3
1.160e-02	-4.46	urinary_tract-bladder-papilloma-inverted	COSMIC cancer mutations	urinary_tract-bladder-papilloma-inverted	4	1	16828	49	FGFR3
1.160e-02	-4.46	skin-face-malignant_melanoma-superficial_spreading	COSMIC cancer mutations	skin-face-malignant_melanoma-superficial_spreading	4	1	16828	49	PREX2
1.160e-02	-4.46	skin-lower_leg-malignant_melanoma-nodular	COSMIC cancer mutations	skin-lower_leg-malignant_melanoma-nodular	4	1	16828	49	PREX2
1.160e-02	-4.46	inverted	COSMIC cancer mutations	inverted	4	1	16828	49	FGFR3
1.169e-02	-4.45	postsynaptic specialization	cellular component	GO:0099572	345	4	19108	49	ERBB4,CADM1,TNIK,CTNND2
1.181e-02	-4.44	HNF1B (HNF1 homeobox B)	protein interactions	6928	188	3	19454	49	NFIA,SOX5,TRPS1
1.182e-02	-4.44	export across plasma membrane	biological process	GO:0140115	60	2	18204	50	SLC4A4,ATP1A2
1.184e-02	-4.44	-	gene3d domains	1.20.58.1060	4	1	14470	43	MACF1
1.192e-02	-4.43	chemical homeostasis	biological process	GO:0048878	914	7	18204	50	SLC1A3,ATP1A2,ZBTB20,RYR3,ATP13A4,SLC4A4,RORA
1.192e-02	-4.43	cartilage development	biological process	GO:0051216	173	3	18204	50	FGFR3,SOX5,NFIA
1.200e-02	-4.42	Erythroid Transcription Factor GATA-1, subunit A	gene3d domains	3.30.50.10	56	2	14470	43	RORA,TRPS1
1.203e-02	-4.42	MAML1 (mastermind like transcriptional coactivator 1)	protein interactions	9794	66	2	19454	49	NFIA,MAML2
1.216e-02	-4.41	parathyroid	COSMIC cancer mutations	parathyroid	476	5	16828	49	GPM6A,TRPS1,GPC5,RYR3,MACF1
1.223e-02	-4.40	monoatomic cation homeostasis	biological process	GO:0055080	505	5	18204	50	ATP1A2,RYR3,SLC1A3,ATP13A4,SLC4A4
1.229e-02	-4.40	Ion transport by P-type ATPases	REACTOME pathways	R-HSA-936837	58	2	10285	30	ATP13A4,ATP1A2
1.244e-02	-4.39	carboxylic acid transmembrane transporter activity	molecular function	GO:0046943	186	3	18094	47	SLC1A2,SLC1A3,SFXN5
1.253e-02	-4.38	SYT13 (synaptotagmin 13)	protein interactions	57586	5	1	19454	49	NRXN1
1.253e-02	-4.38	ARSI (arylsulfatase family member I)	protein interactions	340075	5	1	19454	49	AHCYL2
1.253e-02	-4.38	NRG2 (neuregulin 2)	protein interactions	9542	5	1	19454	49	ERBB4
1.253e-02	-4.38	PTGER2 (prostaglandin E receptor 2)	protein interactions	5732	5	1	19454	49	PTGDS
1.253e-02	-4.38	RFX4 (regulatory factor X4)	protein interactions	5992	5	1	19454	49	RFX4
1.253e-02	-4.38	Hk3 (hexokinase 3)	protein interactions	25060	5	1	19454	49	PTGDS
1.259e-02	-4.38	regulation of carbohydrate catabolic process	biological process	GO:0043470	62	2	18204	50	SLC4A4,ZBTB20
1.262e-02	-4.37	organic acid transmembrane transporter activity	molecular function	GO:0005342	187	3	18094	47	SLC1A2,SFXN5,SLC1A3
1.262e-02	-4.37	bone-pelvis-chondrosarcoma	COSMIC cancer mutations	bone-pelvis-chondrosarcoma	311	4	16828	49	LSAMP,PARD3B,COL5A3,ERBB4
1.262e-02	-4.37	Ig-like_fold	interpro domains	IPR013783	721	6	18521	50	NTM,LRIG1,LSAMP,PTPRZ1,CADM1,FGFR3
1.275e-02	-4.36	L-amino acid transmembrane transporter activity	molecular function	GO:0015179	66	2	18094	47	SLC1A2,SLC1A3
1.292e-02	-4.35	neuroligin family protein binding	molecular function	GO:0097109	5	1	18094	47	NRXN1
1.292e-02	-4.35	fibroblast growth factor receptor activity	molecular function	GO:0005007	5	1	18094	47	FGFR3
1.302e-02	-4.34	pancreas-carcinoma	COSMIC cancer mutations	pancreas-carcinoma	14770	48	16828	49	TRPS1,SOX5,RORA,ABLIM1,PTGDS,COL5A3,NKAIN3,SFXN5,GPC5,CTNND2,QKI,AHCYL2,SLC1A2,NPAS3,ERBB4,PARD3B,NRXN1,PREX2,MAML2,RFX4,CST3,MSI2,NCKAP5,FGFR3,ATP13A4,ACSS1,ZNF98,PITPNC1,PTPRZ1,NFIA,CDH20,TNIK,HIF3A,FBXL7,GPM6A,ITPR2,LSAMP,PCDH9,MACF1,CADM1,SLC4A4,NHSL1,RYR3,ATP1A2,SLC1A3,ZBTB20,NTM,LRIG1
1.310e-02	-4.34	central_nervous_system-brain-primitive_neuroectodermal_tumour-medulloblastoma-medullomyoblastoma	COSMIC cancer mutations	central_nervous_system-brain-primitive_neuroectodermal_tumour-medulloblastoma-medullomyoblastoma	485	5	16828	49	ATP13A4,RYR3,LSAMP,PCDH9,SLC4A4
1.310e-02	-4.34	medullomyoblastoma	COSMIC cancer mutations	medullomyoblastoma	485	5	16828	49	RYR3,ATP13A4,SLC4A4,PCDH9,LSAMP
1.311e-02	-4.33	Signaling by BRAF and RAF fusions	REACTOME pathways	R-HSA-6802952	60	2	10285	30	MACF1,QKI
1.314e-02	-4.33	inorganic ion transmembrane transport	biological process	GO:0098660	715	6	18204	50	SLC1A3,ATP1A2,GPM6A,RYR3,SLC4A4,ITPR2
1.321e-02	-4.33	non_small_cell_carcinoma	COSMIC cancer mutations	non_small_cell_carcinoma	5198	23	16828	49	RORA,LSAMP,ITPR2,ABLIM1,COL5A3,PTPRZ1,TRPS1,PITPNC1,TNIK,FBXL7,HIF3A,SOX5,MSI2,FGFR3,ATP13A4,SLC1A3,LRIG1,NPAS3,ERBB4,QKI,CTNND2,PREX2,MAML2
1.321e-02	-4.33	lung-carcinoma-non_small_cell_carcinoma	COSMIC cancer mutations	lung-carcinoma-non_small_cell_carcinoma	5198	23	16828	49	CTNND2,QKI,NPAS3,ERBB4,PREX2,MAML2,MSI2,FGFR3,ATP13A4,SLC1A3,LRIG1,PITPNC1,PTPRZ1,TRPS1,TNIK,SOX5,HIF3A,FBXL7,RORA,ITPR2,LSAMP,ABLIM1,COL5A3
1.322e-02	-4.33	monoatomic ion homeostasis	biological process	GO:0050801	515	5	18204	50	ATP1A2,SLC4A4,SLC1A3,ATP13A4,RYR3
1.332e-02	-4.32	human chr13q21.32	chromosome location	human chr13q21.32	7	1	26134	50	PCDH9
1.332e-02	-4.32	human chr8q13.2	chromosome location	human chr8q13.2	7	1	26134	50	PREX2
1.343e-02	-4.31	Na/HCO3_transpt	interpro domains	IPR003024	5	1	18521	50	SLC4A4
1.343e-02	-4.31	Protocadherin	interpro domains	IPR013585	5	1	18521	50	PCDH9
1.343e-02	-4.31	PI_transfer	interpro domains	IPR001666	5	1	18521	50	PITPNC1
1.343e-02	-4.31	BBP-like	interpro domains	IPR045071	5	1	18521	50	QKI
1.343e-02	-4.31	Vinculin/catenin	interpro domains	IPR006077	5	1	18521	50	CTNNA2
1.343e-02	-4.31	Mtc	interpro domains	IPR004686	5	1	18521	50	SFXN5
1.343e-02	-4.31	P-type_TPase_V	interpro domains	IPR006544	5	1	18521	50	ATP13A4
1.357e-02	-4.30	NFIX (nuclear factor I X)	protein interactions	4784	198	3	19454	49	TRPS1,SOX5,NFIA
1.366e-02	-4.29	stem cell differentiation	biological process	GO:0048863	182	3	18204	50	ERBB4,MSI2,GPM6A
1.366e-02	-4.29	amygdala development	biological process	GO:0021764	5	1	18204	50	ATP1A2
1.366e-02	-4.29	propionate metabolic process	biological process	GO:0019541	5	1	18204	50	ACSS1
1.366e-02	-4.29	gephyrin clustering involved in postsynaptic density assembly	biological process	GO:0097116	5	1	18204	50	NRXN1
1.366e-02	-4.29	ERBB2-ERBB4 signaling pathway	biological process	GO:0038135	5	1	18204	50	ERBB4
1.366e-02	-4.29	otolith morphogenesis	biological process	GO:0032474	5	1	18204	50	LRIG1
1.366e-02	-4.29	tricarboxylic acid transport	biological process	GO:0006842	5	1	18204	50	SFXN5
1.366e-02	-4.29	citrate transport	biological process	GO:0015746	5	1	18204	50	SFXN5
1.367e-02	-4.29	neoplasm	COSMIC cancer mutations	neoplasm	14787	48	16828	49	RYR3,NHSL1,SLC4A4,CADM1,ZBTB20,DTNA,ATP1A2,SLC1A3,LRIG1,NTM,TNIK,FBXL7,HIF3A,PTPRZ1,NFIA,ZNF98,CDH20,GPM6A,LSAMP,ITPR2,MACF1,PCDH9,PREX2,MAML2,ERBB4,NPAS3,QKI,AHCYL2,CTNND2,SLC1A2,NRXN1,PARD3B,ACSS1,CST3,MSI2,RFX4,FGFR3,ATP13A4,NCKAP5,SOX5,TRPS1,NKAIN3,COL5A3,GPC5,SFXN5,RORA,PTGDS,ABLIM1
1.371e-02	-4.29	ALPHACATENIN	prints domains	PR00805	4	1	5227	18	CTNNA2
1.372e-02	-4.29	CTF_NFI_2	prosite domains	PS51080	4	1	12186	42	NFIA
1.372e-02	-4.29	CTF_NFI_1	prosite domains	PS00349	4	1	12186	42	NFIA
1.375e-02	-4.29	skin-upper_back-malignant_melanoma	COSMIC cancer mutations	skin-upper_back-malignant_melanoma	319	4	16828	49	ERBB4,MACF1,GPC5,PARD3B
1.383e-02	-4.28	ANK2 (ankyrin 2)	protein interactions	287	71	2	19454	49	TNIK,GPM6A
1.383e-02	-4.28	UNKL (unk like zinc finger)	protein interactions	64718	71	2	19454	49	AHCYL2,QKI
1.386e-02	-4.28	regulation of carbohydrate metabolic process	biological process	GO:0006109	183	3	18204	50	RORA,SLC4A4,ZBTB20
1.397e-02	-4.27	IP_trans	pfam domains	PF02121	5	1	17795	50	PITPNC1
1.397e-02	-4.27	SFXNs	pfam domains	PF03820	5	1	17795	50	SFXN5
1.397e-02	-4.27	Protocadherin	pfam domains	PF08374	5	1	17795	50	PCDH9
1.397e-02	-4.27	Vinculin	pfam domains	PF01044	5	1	17795	50	CTNNA2
1.412e-02	-4.26	neuron to neuron synapse	cellular component	GO:0098984	365	4	19108	49	CADM1,ERBB4,TNIK,CTNND2
1.413e-02	-4.26	TIAM1 (TIAM Rac1 associated GEF 1)	protein interactions	7074	201	3	19454	49	RYR3,DTNA,ATP1A2
1.413e-02	-4.26	lower_leg	COSMIC cancer mutations	lower_leg	174	3	16828	49	ERBB4,PREX2,FGFR3
1.418e-02	-4.26	hepatocellular_carcinoma	COSMIC cancer mutations	hepatocellular_carcinoma	14800	48	16828	49	RYR3,SLC4A4,NHSL1,CADM1,LRIG1,NTM,ZBTB20,ATP1A2,SLC1A3,DTNA,FBXL7,HIF3A,TNIK,CDH20,PTPRZ1,NFIA,ZNF98,PITPNC1,LSAMP,ITPR2,PCDH9,MACF1,GPM6A,MAML2,PREX2,NRXN1,PARD3B,ERBB4,NPAS3,AHCYL2,QKI,CTNND2,SLC1A2,ACSS1,FGFR3,ATP13A4,NCKAP5,CST3,RFX4,SOX5,TRPS1,GPC5,SFXN5,NKAIN3,COL5A3,PTGDS,ABLIM1,RORA
1.418e-02	-4.26	liver-carcinoma-hepatocellular_carcinoma	COSMIC cancer mutations	liver-carcinoma-hepatocellular_carcinoma	14800	48	16828	49	CST3,RFX4,ATP13A4,FGFR3,NCKAP5,ACSS1,ERBB4,NPAS3,SLC1A2,CTNND2,AHCYL2,QKI,NRXN1,PARD3B,PREX2,MAML2,RORA,PTGDS,ABLIM1,NKAIN3,COL5A3,GPC5,SFXN5,TRPS1,SOX5,ZBTB20,DTNA,SLC1A3,ATP1A2,LRIG1,NTM,CADM1,RYR3,SLC4A4,NHSL1,GPM6A,PCDH9,MACF1,LSAMP,ITPR2,NFIA,PTPRZ1,PITPNC1,ZNF98,CDH20,TNIK,FBXL7,HIF3A
1.418e-02	-4.26	positive regulation of tyrosine phosphorylation of STAT protein	biological process	GO:0042531	66	2	18204	50	FGFR3,ERBB4
1.418e-02	-4.26	L-alpha-amino acid transmembrane transport	biological process	GO:1902475	66	2	18204	50	SLC1A3,SLC1A2
1.420e-02	-4.25	DPYSL3 (dihydropyrimidinase like 3)	protein interactions	1809	72	2	19454	49	TNIK,GPM6A
1.432e-02	-4.25	FEV (FEV transcription factor, ETS family member)	protein interactions	54738	202	3	19454	49	NFIA,TRPS1,SOX5
1.448e-02	-4.24	skin-lower_leg-malignant_melanoma-superficial_spreading	COSMIC cancer mutations	skin-lower_leg-malignant_melanoma-superficial_spreading	5	1	16828	49	PREX2
1.448e-02	-4.24	skin-lower_back-other-nevus_sebaceous	COSMIC cancer mutations	skin-lower_back-other-nevus_sebaceous	5	1	16828	49	FGFR3
1.448e-02	-4.24	skin-face-other-nevus_sebaceous	COSMIC cancer mutations	skin-face-other-nevus_sebaceous	5	1	16828	49	FGFR3
1.448e-02	-4.24	skin-shoulder-other-nevus_sebaceous	COSMIC cancer mutations	skin-shoulder-other-nevus_sebaceous	5	1	16828	49	FGFR3
1.448e-02	-4.24	skin-hand-other-lichenoid_keratosis	COSMIC cancer mutations	skin-hand-other-lichenoid_keratosis	5	1	16828	49	FGFR3
1.448e-02	-4.24	skin-other-lichenoid_keratosis	COSMIC cancer mutations	skin-other-lichenoid_keratosis	5	1	16828	49	FGFR3
1.448e-02	-4.24	skin-breast-other-lichenoid_keratosis	COSMIC cancer mutations	skin-breast-other-lichenoid_keratosis	5	1	16828	49	FGFR3
1.448e-02	-4.24	skin-adnexal_tumour-syringocystadenoma_papilliferum	COSMIC cancer mutations	skin-adnexal_tumour-syringocystadenoma_papilliferum	5	1	16828	49	FGFR3
1.448e-02	-4.24	skin-neck-other-lichenoid_keratosis	COSMIC cancer mutations	skin-neck-other-lichenoid_keratosis	5	1	16828	49	FGFR3
1.448e-02	-4.24	skin-flank-other-lichenoid_keratosis	COSMIC cancer mutations	skin-flank-other-lichenoid_keratosis	5	1	16828	49	FGFR3
1.448e-02	-4.24	skin-scalp-other-nevus_sebaceous	COSMIC cancer mutations	skin-scalp-other-nevus_sebaceous	5	1	16828	49	FGFR3
1.448e-02	-4.24	skin-breast-other-nevus_sebaceous	COSMIC cancer mutations	skin-breast-other-nevus_sebaceous	5	1	16828	49	FGFR3
1.448e-02	-4.24	monoclonal_gammopathy_of_undetermined_significance	COSMIC cancer mutations	monoclonal_gammopathy_of_undetermined_significance	5	1	16828	49	FGFR3
1.448e-02	-4.24	skin-arm-other-seborrhoeic_keratosis	COSMIC cancer mutations	skin-arm-other-seborrhoeic_keratosis	5	1	16828	49	FGFR3
1.448e-02	-4.24	skin-hip-other-seborrhoeic_keratosis	COSMIC cancer mutations	skin-hip-other-seborrhoeic_keratosis	5	1	16828	49	FGFR3
1.448e-02	-4.24	skin-neck-other-nevus_sebaceous	COSMIC cancer mutations	skin-neck-other-nevus_sebaceous	5	1	16828	49	FGFR3
1.448e-02	-4.24	syringocystadenoma_papilliferum	COSMIC cancer mutations	syringocystadenoma_papilliferum	5	1	16828	49	FGFR3
1.448e-02	-4.24	skin-upper_arm-other-lichenoid_keratosis	COSMIC cancer mutations	skin-upper_arm-other-lichenoid_keratosis	5	1	16828	49	FGFR3
1.448e-02	-4.24	skin-lower_leg-other-lichenoid_keratosis	COSMIC cancer mutations	skin-lower_leg-other-lichenoid_keratosis	5	1	16828	49	FGFR3
1.448e-02	-4.24	skin-face-other-lichenoid_keratosis	COSMIC cancer mutations	skin-face-other-lichenoid_keratosis	5	1	16828	49	FGFR3
1.448e-02	-4.24	skin-lower_back-other-lichenoid_keratosis	COSMIC cancer mutations	skin-lower_back-other-lichenoid_keratosis	5	1	16828	49	FGFR3
1.448e-02	-4.24	skin-forearm-other-lichenoid_keratosis	COSMIC cancer mutations	skin-forearm-other-lichenoid_keratosis	5	1	16828	49	FGFR3
1.448e-02	-4.24	skin-forearm-other-seborrhoeic_keratosis	COSMIC cancer mutations	skin-forearm-other-seborrhoeic_keratosis	5	1	16828	49	FGFR3
1.448e-02	-4.24	skin-upper_back-other-lichenoid_keratosis	COSMIC cancer mutations	skin-upper_back-other-lichenoid_keratosis	5	1	16828	49	FGFR3
1.448e-02	-4.24	skin-ear-other-nevus_sebaceous	COSMIC cancer mutations	skin-ear-other-nevus_sebaceous	5	1	16828	49	FGFR3
1.448e-02	-4.24	skin-chest-other-lichenoid_keratosis	COSMIC cancer mutations	skin-chest-other-lichenoid_keratosis	5	1	16828	49	FGFR3
1.448e-02	-4.24	skin-shoulder-other-lichenoid_keratosis	COSMIC cancer mutations	skin-shoulder-other-lichenoid_keratosis	5	1	16828	49	FGFR3
1.448e-02	-4.24	lichenoid_keratosis	COSMIC cancer mutations	lichenoid_keratosis	5	1	16828	49	FGFR3
1.448e-02	-4.24	skin-upper_leg-other-lichenoid_keratosis	COSMIC cancer mutations	skin-upper_leg-other-lichenoid_keratosis	5	1	16828	49	FGFR3
1.448e-02	-4.24	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-monoclonal_gammopathy_of_undetermined_significance	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-monoclonal_gammopathy_of_undetermined_significance	5	1	16828	49	FGFR3
1.449e-02	-4.23	large_intestine-colon-carcinoma	COSMIC cancer mutations	large_intestine-colon-carcinoma	2612	14	16828	49	AHCYL2,PTPRZ1,TRPS1,NRXN1,PREX2,RORA,ITPR2,MACF1,PCDH9,COL5A3,SLC1A3,GPC5,ACSS1,LRIG1
1.470e-02	-4.22	NFIC (nuclear factor I C)	protein interactions	4782	204	3	19454	49	TRPS1,SOX5,NFIA
1.493e-02	-4.20	presynapse	cellular component	GO:0098793	569	5	19108	49	TNIK,GPM6A,SLC1A2,ERBB4,NRXN1
1.496e-02	-4.20	TEC (tec protein tyrosine kinase)	protein interactions	7006	74	2	19454	49	ERBB4,MSI2
1.502e-02	-4.20	SYTL3 (synaptotagmin like 3)	protein interactions	94120	6	1	19454	49	NRXN1
1.502e-02	-4.20	FGF23 (fibroblast growth factor 23)	protein interactions	8074	6	1	19454	49	FGFR3
1.502e-02	-4.20	SOX11 (SRY-box transcription factor 11)	protein interactions	6664	6	1	19454	49	SOX5
1.502e-02	-4.20	FGF6 (fibroblast growth factor 6)	protein interactions	2251	6	1	19454	49	FGFR3
1.502e-02	-4.20	SOX1 (SRY-box transcription factor 1)	protein interactions	6656	6	1	19454	49	SOX5
1.502e-02	-4.20	FGF18 (fibroblast growth factor 18)	protein interactions	8817	6	1	19454	49	FGFR3
1.502e-02	-4.20	SLC12A5 (solute carrier family 12 member 5)	protein interactions	57468	6	1	19454	49	GPM6A
1.502e-02	-4.20	Tiam2 (T cell lymphoma invasion and metastasis 2)	protein interactions	24001	6	1	19454	49	DTNA
1.502e-02	-4.20	PBP2 (Pbp2p)	protein interactions	852533	6	1	19454	49	QKI
1.502e-02	-4.20	DAZ4 (deleted in azoospermia 4)	protein interactions	57135	6	1	19454	49	QKI
1.502e-02	-4.20	DRP2 (dystrophin related protein 2)	protein interactions	1821	6	1	19454	49	DTNA
1.502e-02	-4.20	CYRIA (CYFIP related Rac1 interactor A)	protein interactions	81553	6	1	19454	49	GPM6A
1.502e-02	-4.20	NRG4 (neuregulin 4)	protein interactions	145957	6	1	19454	49	ERBB4
1.511e-02	-4.19	Calcium signaling pathway	KEGG pathways	hsa04020	181	3	7161	21	ITPR2,RYR3,ERBB4
1.511e-02	-4.19	Calcium signaling pathway	KEGG pathways	ko04020	181	3	7161	21	RYR3,ITPR2,ERBB4
1.527e-02	-4.18	Constitutive Signaling by Aberrant PI3K in Cancer	REACTOME pathways	R-HSA-2219530	65	2	10285	30	FGFR3,ERBB4
1.547e-02	-4.17	cell-cell contact zone	cellular component	GO:0044291	74	2	19108	49	ATP1A2,PCDH9
1.549e-02	-4.17	steroid hormone binding	molecular function	GO:1990239	6	1	18094	47	ATP1A2
1.549e-02	-4.17	calcium-induced calcium release activity	molecular function	GO:0048763	6	1	18094	47	RYR3
1.549e-02	-4.17	sodium:bicarbonate symporter activity	molecular function	GO:0008510	6	1	18094	47	SLC4A4
1.553e-02	-4.16	IG_LIKE	prosite domains	PS50835	430	5	12186	42	FGFR3,CADM1,NTM,LSAMP,LRIG1
1.573e-02	-4.15	MIR200A (microRNA 200a)	protein interactions	406983	76	2	19454	49	QKI,MSI2
1.583e-02	-4.15	MARCKS (myristoylated alanine rich protein kinase C substrate)	protein interactions	4082	588	5	19454	49	MACF1,ABLIM1,SLC1A3,AHCYL2,DTNA
1.597e-02	-4.14	Synaptic Vesicle Pathway	WikiPathways	WP2267	52	2	5310	20	SLC1A3,ATP1A2
1.600e-02	-4.14	IG	smart domains	SM00409	394	5	9717	37	FGFR3,LRIG1,LSAMP,CADM1,NTM
1.600e-02	-4.13	other	COSMIC cancer mutations	other	14843	48	16828	49	SLC1A3,ATP1A2,DTNA,ZBTB20,NTM,LRIG1,SLC4A4,NHSL1,RYR3,CADM1,GPM6A,PCDH9,MACF1,ITPR2,LSAMP,TNIK,HIF3A,FBXL7,ZNF98,NFIA,PTPRZ1,CDH20,ACSS1,RFX4,CST3,MSI2,NCKAP5,ATP13A4,FGFR3,PREX2,MAML2,SLC1A2,QKI,CTNND2,AHCYL2,ERBB4,NPAS3,PARD3B,NRXN1,COL5A3,NKAIN3,SFXN5,GPC5,RORA,ABLIM1,PTGDS,SOX5,TRPS1
1.609e-02	-4.13	EF-hand_dom_typ1	interpro domains	IPR015153	6	1	18521	50	DTNA
1.609e-02	-4.13	P-type_ATPase_IIC	interpro domains	IPR005775	6	1	18521	50	ATP1A2
1.609e-02	-4.13	EF-hand_dom_typ2	interpro domains	IPR015154	6	1	18521	50	DTNA
1.609e-02	-4.13	GAR_dom_sf	interpro domains	IPR036534	6	1	18521	50	MACF1
1.609e-02	-4.13	Glypican_CS	interpro domains	IPR019803	6	1	18521	50	GPC5
1.609e-02	-4.13	Syndecan/Neurexin_dom	interpro domains	IPR027789	6	1	18521	50	NRXN1
1.609e-02	-4.13	GF_recep_IV	interpro domains	IPR032778	6	1	18521	50	ERBB4
1.609e-02	-4.13	GAR_dom	interpro domains	IPR003108	6	1	18521	50	MACF1
1.609e-02	-4.13	Desmoplakin_SH3	interpro domains	IPR041615	6	1	18521	50	MACF1
1.609e-02	-4.13	Glypican	interpro domains	IPR001863	6	1	18521	50	GPC5
1.627e-02	-4.12	sarcoplasmic reticulum	cellular component	GO:0016529	76	2	19108	49	ITPR2,RYR3
1.637e-02	-4.11	ERBB4-ERBB4 signaling pathway	biological process	GO:0038138	6	1	18204	50	ERBB4
1.637e-02	-4.11	negative regulation of extracellular matrix disassembly	biological process	GO:0010716	6	1	18204	50	CST3
1.637e-02	-4.11	asymmetric neuroblast division	biological process	GO:0055059	6	1	18204	50	SOX5
1.637e-02	-4.11	vocal learning	biological process	GO:0042297	6	1	18204	50	NRXN1
1.637e-02	-4.11	imitative learning	biological process	GO:0098596	6	1	18204	50	NRXN1
1.637e-02	-4.11	gamma-aminobutyric acid biosynthetic process	biological process	GO:0009449	6	1	18204	50	SLC1A3
1.637e-02	-4.11	postsynaptic density protein 95 clustering	biological process	GO:0097119	6	1	18204	50	NRXN1
1.652e-02	-4.10	ANKRD40 (ankyrin repeat domain 40)	protein interactions	91369	78	2	19454	49	MSI2,SOX5
1.652e-02	-4.10	MIR34C (microRNA 34c)	protein interactions	407042	78	2	19454	49	QKI,MSI2
1.672e-02	-4.09	regulation of ATP metabolic process	biological process	GO:1903578	72	2	18204	50	SLC4A4,ZBTB20
1.674e-02	-4.09	SH3_10	pfam domains	PF17902	6	1	17795	50	MACF1
1.674e-02	-4.09	Syndecan	pfam domains	PF01034	6	1	17795	50	NRXN1
1.674e-02	-4.09	EF-hand_3	pfam domains	PF09069	6	1	17795	50	DTNA
1.674e-02	-4.09	Glypican	pfam domains	PF01153	6	1	17795	50	GPC5
1.674e-02	-4.09	Plectin	pfam domains	PF00681	6	1	17795	50	MACF1
1.674e-02	-4.09	EF-hand_2	pfam domains	PF09068	6	1	17795	50	DTNA
1.674e-02	-4.09	GF_recep_IV	pfam domains	PF14843	6	1	17795	50	ERBB4
1.674e-02	-4.09	GAS2	pfam domains	PF02187	6	1	17795	50	MACF1
1.693e-02	-4.08	FBXO45 (F-box protein 45)	protein interactions	200933	79	2	19454	49	CTNNA2,NCKAP5
1.693e-02	-4.08	PRDM1 (PR/SET domain 1)	protein interactions	639	79	2	19454	49	TRPS1,NFIA
1.705e-02	-4.07	HAD_sf	interpro domains	IPR023214	74	2	18521	50	ATP1A2,ATP13A4
1.709e-02	-4.07	skin-extremity-malignant_melanoma	COSMIC cancer mutations	skin-extremity-malignant_melanoma	1875	11	16828	49	ACSS1,RYR3,FBXL7,COL5A3,PREX2,PCDH9,ATP13A4,CDH20,PITPNC1,ERBB4,PTPRZ1
1.709e-02	-4.07	human chr2q21.2	chromosome location	human chr2q21.2	9	1	26134	50	NCKAP5
1.711e-02	-4.07	NAHCO3TRSPRT	prints domains	PR01232	5	1	5227	18	SLC4A4
1.711e-02	-4.07	PITRANSFER	prints domains	PR00391	5	1	5227	18	PITPNC1
1.716e-02	-4.07	regulation of cartilage development	biological process	GO:0061035	73	2	18204	50	TRPS1,SOX5
1.731e-02	-4.06	GFAP (glial fibrillary acidic protein)	protein interactions	2670	217	3	19454	49	NKAIN3,ABLIM1,RORA
1.735e-02	-4.05	skin-forearm-malignant_melanoma-superficial_spreading	COSMIC cancer mutations	skin-forearm-malignant_melanoma-superficial_spreading	6	1	16828	49	PREX2
1.735e-02	-4.05	skin-adnexal_tumour-trichoblastoma	COSMIC cancer mutations	skin-adnexal_tumour-trichoblastoma	6	1	16828	49	FGFR3
1.735e-02	-4.05	skin-upper_leg-other-seborrhoeic_keratosis	COSMIC cancer mutations	skin-upper_leg-other-seborrhoeic_keratosis	6	1	16828	49	FGFR3
1.735e-02	-4.05	skin-lower_back-other-seborrhoeic_keratosis	COSMIC cancer mutations	skin-lower_back-other-seborrhoeic_keratosis	6	1	16828	49	FGFR3
1.735e-02	-4.05	kidney-carcinoma-collecting_duct_carcinoma	COSMIC cancer mutations	kidney-carcinoma-collecting_duct_carcinoma	6	1	16828	49	FGFR3
1.735e-02	-4.05	skin-head_neck-malignant_melanoma	COSMIC cancer mutations	skin-head_neck-malignant_melanoma	6	1	16828	49	PREX2
1.735e-02	-4.05	skin-abdomen-other-seborrhoeic_keratosis	COSMIC cancer mutations	skin-abdomen-other-seborrhoeic_keratosis	6	1	16828	49	FGFR3
1.735e-02	-4.05	skin-flank-other-seborrhoeic_keratosis	COSMIC cancer mutations	skin-flank-other-seborrhoeic_keratosis	6	1	16828	49	FGFR3
1.735e-02	-4.05	autonomic_ganglia-paraganglioma-benign	COSMIC cancer mutations	autonomic_ganglia-paraganglioma-benign	6	1	16828	49	NHSL1
1.735e-02	-4.05	skin-trunk-epidermal_nevus	COSMIC cancer mutations	skin-trunk-epidermal_nevus	6	1	16828	49	FGFR3
1.735e-02	-4.05	skin-back-other-seborrhoeic_keratosis	COSMIC cancer mutations	skin-back-other-seborrhoeic_keratosis	6	1	16828	49	FGFR3
1.735e-02	-4.05	skin-epidermal_nevus	COSMIC cancer mutations	skin-epidermal_nevus	6	1	16828	49	FGFR3
1.735e-02	-4.05	skin-head_neck-epidermal_nevus	COSMIC cancer mutations	skin-head_neck-epidermal_nevus	6	1	16828	49	FGFR3
1.735e-02	-4.05	skin-face-other-seborrhoeic_keratosis	COSMIC cancer mutations	skin-face-other-seborrhoeic_keratosis	6	1	16828	49	FGFR3
1.735e-02	-4.05	collecting_duct_carcinoma	COSMIC cancer mutations	collecting_duct_carcinoma	6	1	16828	49	FGFR3
1.735e-02	-4.05	skin-lower_leg-epidermal_nevus	COSMIC cancer mutations	skin-lower_leg-epidermal_nevus	6	1	16828	49	FGFR3
1.735e-02	-4.05	skin-in_situ_epithelial_neoplasm-actinic_keratosis	COSMIC cancer mutations	skin-in_situ_epithelial_neoplasm-actinic_keratosis	6	1	16828	49	FGFR3
1.735e-02	-4.05	skin-in_situ_epithelial_neoplasm-Bowen_disease	COSMIC cancer mutations	skin-in_situ_epithelial_neoplasm-Bowen_disease	6	1	16828	49	FGFR3
1.735e-02	-4.05	skin-arm-epidermal_nevus	COSMIC cancer mutations	skin-arm-epidermal_nevus	6	1	16828	49	FGFR3
1.735e-02	-4.05	skin-benign_melanocytic_nevus-lentiginous_nevus	COSMIC cancer mutations	skin-benign_melanocytic_nevus-lentiginous_nevus	6	1	16828	49	FGFR3
1.735e-02	-4.05	lentiginous_nevus	COSMIC cancer mutations	lentiginous_nevus	6	1	16828	49	FGFR3
1.740e-02	-4.05	actin filament binding	molecular function	GO:0051015	211	3	18094	47	ABLIM1,CTNNA2,MACF1
1.750e-02	-4.05	Pum2 (pumilio RNA-binding family member 2)	protein interactions	80913	7	1	19454	49	QKI
1.750e-02	-4.05	FGF5 (fibroblast growth factor 5)	protein interactions	2250	7	1	19454	49	FGFR3
1.750e-02	-4.05	SLC16A5 (solute carrier family 16 member 5)	protein interactions	9121	7	1	19454	49	PTPRZ1
1.750e-02	-4.05	ABCC12 (ATP binding cassette subfamily C member 12)	protein interactions	94160	7	1	19454	49	NPAS3
1.750e-02	-4.05	Ahcyl1 (S-adenosylhomocysteine hydrolase-like 1)	protein interactions	229709	7	1	19454	49	AHCYL2
1.750e-02	-4.05	ZBTB45 (zinc finger and BTB domain containing 45)	protein interactions	84878	7	1	19454	49	ZBTB20
1.761e-02	-4.04	positive regulation of gliogenesis	biological process	GO:0014015	74	2	18204	50	QKI,PTPRZ1
1.768e-02	-4.04	ovary-carcinoma	COSMIC cancer mutations	ovary-carcinoma	933	7	16828	49	ATP1A2,PREX2,TNIK,ITPR2,MACF1,FGFR3,ERBB4
1.770e-02	-4.03	Plakin repeat	gene3d domains	3.90.1290.10	6	1	14470	43	MACF1
1.770e-02	-4.03	Gas2-like domain	gene3d domains	3.30.920.20	6	1	14470	43	MACF1
1.774e-02	-4.03	SOX17 (SRY-box transcription factor 17)	protein interactions	64321	81	2	19454	49	NFIA,TRPS1
1.802e-02	-4.02	Bile secretion	KEGG pathways	ko04976	71	2	7161	21	SLC4A4,ATP1A2
1.802e-02	-4.02	Bile secretion	KEGG pathways	hsa04976	71	2	7161	21	ATP1A2,SLC4A4
1.803e-02	-4.02	SOX2 (SRY-box transcription factor 2)	protein interactions	6657	1342	8	19454	49	SOX5,QKI,MACF1,TRPS1,ITPR2,LSAMP,MSI2,NFIA
1.804e-02	-4.01	phosphatidic acid transfer activity	molecular function	GO:1990050	7	1	18094	47	PITPNC1
1.804e-02	-4.01	P-type sodium transporter activity	molecular function	GO:0008554	7	1	18094	47	ATP1A2
1.804e-02	-4.01	P-type sodium:potassium-exchanging transporter activity	molecular function	GO:0005391	7	1	18094	47	ATP1A2
1.847e-02	-3.99	FBXO2 (F-box protein 2)	protein interactions	26232	403	4	19454	49	PCDH9,LRIG1,NTM,FGFR3
1.852e-02	-3.99	regulation of tyrosine phosphorylation of STAT protein	biological process	GO:0042509	76	2	18204	50	FGFR3,ERBB4
1.858e-02	-3.99	SYT1 (synaptotagmin 1)	protein interactions	6857	83	2	19454	49	NRXN1,GPM6A
1.858e-02	-3.99	PAX2 (paired box 2)	protein interactions	5076	83	2	19454	49	NFIA,TRPS1
1.858e-02	-3.99	DNM3 (dynamin 3)	protein interactions	26052	83	2	19454	49	FGFR3,GPM6A
1.872e-02	-3.98	calcium ion transmembrane transport	biological process	GO:0070588	205	3	18204	50	RYR3,ITPR2,GPM6A
1.875e-02	-3.98	Rcpt_L-dom	interpro domains	IPR000494	7	1	18521	50	ERBB4
1.875e-02	-3.98	Plectin_repeat	interpro domains	IPR001101	7	1	18521	50	MACF1
1.875e-02	-3.98	Rcpt_L-dom_sf	interpro domains	IPR036941	7	1	18521	50	ERBB4
1.875e-02	-3.98	Alpha-catenin/vinculin-like_sf	interpro domains	IPR036723	7	1	18521	50	CTNNA2
1.875e-02	-3.98	Furin-like_Cys-rich_dom	interpro domains	IPR006211	7	1	18521	50	ERBB4
1.875e-02	-3.98	Plakophilin/d_Catenin	interpro domains	IPR028435	7	1	18521	50	CTNND2
1.875e-02	-3.98	Plakin_repeat_sf	interpro domains	IPR035915	7	1	18521	50	MACF1
1.878e-02	-3.97	transmembrane receptor protein kinase activity	molecular function	GO:0019199	81	2	18094	47	ERBB4,FGFR3
1.882e-02	-3.97	HAD-like_sf	interpro domains	IPR036412	78	2	18521	50	ATP1A2,ATP13A4
1.889e-02	-3.97	haematopoietic_and_lymphoid_tissue	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue	14368	47	16828	49	TRPS1,SOX5,RORA,ABLIM1,COL5A3,NKAIN3,SFXN5,GPC5,QKI,CTNND2,AHCYL2,SLC1A2,ERBB4,NPAS3,NRXN1,PARD3B,PREX2,MAML2,RFX4,MSI2,NCKAP5,FGFR3,ATP13A4,ACSS1,ZNF98,PITPNC1,PTPRZ1,NFIA,CDH20,TNIK,HIF3A,FBXL7,GPM6A,LSAMP,ITPR2,MACF1,PCDH9,CADM1,SLC4A4,NHSL1,RYR3,ATP1A2,SLC1A3,DTNA,ZBTB20,NTM,LRIG1
1.891e-02	-3.97	system process	biological process	GO:0003008	2015	11	18204	50	SLC1A2,SLC1A3,ABLIM1,NRXN1,PTPRZ1,ATP1A2,CTNNA2,RYR3,SLC4A4,LRIG1,DTNA
1.896e-02	-3.97	Immunoglobulins	gene3d domains	2.60.40.10	721	6	14470	43	LSAMP,NTM,LRIG1,PTPRZ1,FGFR3,CADM1
1.897e-02	-3.96	human chr12p11.23	chromosome location	human chr12p11.23	10	1	26134	50	ITPR2
1.898e-02	-3.96	regulation of synaptic transmission, glutamatergic	biological process	GO:0051966	77	2	18204	50	ATP1A2,NRXN1
1.902e-02	-3.96	testis	COSMIC cancer mutations	testis	733	6	16828	49	TRPS1,TNIK,PREX2,ERBB4,MACF1,FGFR3
1.904e-02	-3.96	KLF3 (KLF transcription factor 3)	protein interactions	51274	225	3	19454	49	SOX5,TRPS1,NFIA
1.907e-02	-3.96	cellular response to magnesium ion	biological process	GO:0071286	7	1	18204	50	RYR3
1.907e-02	-3.96	regulation of 3'-UTR-mediated mRNA stabilization	biological process	GO:1905868	7	1	18204	50	QKI
1.907e-02	-3.96	regulation of oligodendrocyte progenitor proliferation	biological process	GO:0070445	7	1	18204	50	PTPRZ1
1.907e-02	-3.96	positive regulation of transcription of Notch receptor target	biological process	GO:0007221	7	1	18204	50	MAML2
1.907e-02	-3.96	glial cell fate specification	biological process	GO:0021780	7	1	18204	50	NFIA
1.907e-02	-3.96	negative regulation of Arp2/3 complex-mediated actin nucleation	biological process	GO:0034316	7	1	18204	50	CTNNA2
1.907e-02	-3.96	S-adenosylmethionine cycle	biological process	GO:0033353	7	1	18204	50	AHCYL2
1.907e-02	-3.96	observational learning	biological process	GO:0098597	7	1	18204	50	NRXN1
1.907e-02	-3.96	regulation of male germ cell proliferation	biological process	GO:2000254	7	1	18204	50	PTGDS
1.911e-02	-3.96	synaptic membrane	cellular component	GO:0097060	400	4	19108	49	GPM6A,SLC1A2,ERBB4,NRXN1
1.914e-02	-3.96	central_nervous_system-brain-glioma-oligodendroglioma_Grade_II	COSMIC cancer mutations	central_nervous_system-brain-glioma-oligodendroglioma_Grade_II	73	2	16828	49	FGFR3,MACF1
1.943e-02	-3.94	mixed_intestinal_and_diffuse_adenocarcinoma-unclassifiable	COSMIC cancer mutations	mixed_intestinal_and_diffuse_adenocarcinoma-unclassifiable	951	7	16828	49	SLC1A2,NCKAP5,MACF1,ITPR2,ATP13A4,PREX2,GPC5
1.943e-02	-3.94	stomach-carcinoma-mixed_intestinal_and_diffuse_adenocarcinoma-unclassifiable	COSMIC cancer mutations	stomach-carcinoma-mixed_intestinal_and_diffuse_adenocarcinoma-unclassifiable	951	7	16828	49	PREX2,GPC5,SLC1A2,ATP13A4,NCKAP5,MACF1,ITPR2
1.944e-02	-3.94	positive regulation of carbohydrate metabolic process	biological process	GO:0045913	78	2	18204	50	ZBTB20,SLC4A4
1.944e-02	-3.94	dicarboxylic acid transport	biological process	GO:0006835	78	2	18204	50	SLC1A3,SLC1A2
1.949e-02	-3.94	Thyroid hormone synthesis	KEGG pathways	hsa04918	74	2	7161	21	ITPR2,ATP1A2
1.949e-02	-3.94	Thyroid hormone synthesis	KEGG pathways	ko04918	74	2	7161	21	ATP1A2,ITPR2
1.951e-02	-3.94	Oncogenic MAPK signaling	REACTOME pathways	R-HSA-6802957	74	2	10285	30	MACF1,QKI
1.951e-02	-3.94	Recep_L_domain	pfam domains	PF01030	7	1	17795	50	ERBB4
1.951e-02	-3.94	Furin-like	pfam domains	PF00757	7	1	17795	50	ERBB4
1.964e-02	-3.93	oligodendroglioma_Grade_II	COSMIC cancer mutations	oligodendroglioma_Grade_II	74	2	16828	49	MACF1,FGFR3
1.974e-02	-3.93	Tyr_kinase_cat_dom	interpro domains	IPR020635	80	2	18521	50	FGFR3,ERBB4
1.986e-02	-3.92	EGLN1 (egl-9 family hypoxia inducible factor 1)	protein interactions	54583	86	2	19454	49	HIF3A,FGFR3
1.991e-02	-3.92	regulation of glial cell differentiation	biological process	GO:0045685	79	2	18204	50	QKI,PTPRZ1
1.998e-02	-3.91	PTGER1 (prostaglandin E receptor 1)	protein interactions	5731	8	1	19454	49	PTGDS
1.998e-02	-3.91	LHB (luteinizing hormone subunit beta)	protein interactions	3972	8	1	19454	49	NTM
1.998e-02	-3.91	DEPP1 (DEPP autophagy regulator 1)	protein interactions	11067	8	1	19454	49	QKI
1.999e-02	-3.91	Gastric acid secretion	KEGG pathways	hsa04971	75	2	7161	21	ITPR2,ATP1A2
1.999e-02	-3.91	Gastric acid secretion	KEGG pathways	ko04971	75	2	7161	21	ITPR2,ATP1A2
2.004e-02	-3.91	somatodendritic compartment	cellular component	GO:0036477	842	6	19108	49	GPM6A,ATP1A2,CTNND2,SLC1A3,NRXN1,CADM1
2.021e-02	-3.90	skin-benign_melanocytic_nevus-intradermal	COSMIC cancer mutations	skin-benign_melanocytic_nevus-intradermal	7	1	16828	49	FGFR3
2.021e-02	-3.90	skin-adnexal_tumour-trichilemmoma	COSMIC cancer mutations	skin-adnexal_tumour-trichilemmoma	7	1	16828	49	FGFR3
2.021e-02	-3.90	skin-shoulder-other-seborrhoeic_keratosis	COSMIC cancer mutations	skin-shoulder-other-seborrhoeic_keratosis	7	1	16828	49	FGFR3
2.021e-02	-3.90	nevus_sebaceous	COSMIC cancer mutations	nevus_sebaceous	7	1	16828	49	FGFR3
2.021e-02	-3.90	skin-face-malignant_melanoma-nodular	COSMIC cancer mutations	skin-face-malignant_melanoma-nodular	7	1	16828	49	PREX2
2.021e-02	-3.90	skin-other-nevus_sebaceous	COSMIC cancer mutations	skin-other-nevus_sebaceous	7	1	16828	49	FGFR3
2.021e-02	-3.90	skin-benign_melanocytic_nevus-compound	COSMIC cancer mutations	skin-benign_melanocytic_nevus-compound	7	1	16828	49	FGFR3
2.021e-02	-3.90	trichilemmoma	COSMIC cancer mutations	trichilemmoma	7	1	16828	49	FGFR3
2.021e-02	-3.90	skin-chest-other-seborrhoeic_keratosis	COSMIC cancer mutations	skin-chest-other-seborrhoeic_keratosis	7	1	16828	49	FGFR3
2.021e-02	-3.90	skin-face-adnexal_tumour-malignant_adnexal_tumour	COSMIC cancer mutations	skin-face-adnexal_tumour-malignant_adnexal_tumour	7	1	16828	49	FGFR3
2.021e-02	-3.90	urinary_tract-carcinoma-transitional_cell_carcinoma	COSMIC cancer mutations	urinary_tract-carcinoma-transitional_cell_carcinoma	7	1	16828	49	FGFR3
2.021e-02	-3.90	skin-upper_leg-malignant_melanoma-nodular	COSMIC cancer mutations	skin-upper_leg-malignant_melanoma-nodular	7	1	16828	49	PREX2
2.021e-02	-3.90	skin-neck-other-seborrhoeic_keratosis	COSMIC cancer mutations	skin-neck-other-seborrhoeic_keratosis	7	1	16828	49	FGFR3
2.025e-02	-3.90	FGFR3b ligand binding and activation	REACTOME pathways	R-HSA-190371	7	1	10285	30	FGFR3
2.025e-02	-3.90	Nectin/Necl trans heterodimerization	REACTOME pathways	R-HSA-420597	7	1	10285	30	CADM1
2.029e-02	-3.90	ZNF608 (zinc finger protein 608)	protein interactions	57507	87	2	19454	49	NFIA,SOX5
2.029e-02	-3.90	MIR141 (microRNA 141)	protein interactions	406933	87	2	19454	49	QKI,MSI2
2.029e-02	-3.90	Kctd5 (potassium channel tetramerisation domain containing 5)	protein interactions	69259	87	2	19454	49	SLC1A3,TRPS1
2.029e-02	-3.90	NHLH1 (nescient helix-loop-helix 1)	protein interactions	4807	87	2	19454	49	TRPS1,NFIA
2.035e-02	-3.89	HAD superfamily/HAD-like	gene3d domains	3.40.50.1000	74	2	14470	43	ATP1A2,ATP13A4
2.043e-02	-3.89	acral_lentiginous	COSMIC cancer mutations	acral_lentiginous	745	6	16828	49	MACF1,FGFR3,CDH20,ATP13A4,ERBB4,PREX2
2.044e-02	-3.89	Signaling by EGFR	REACTOME pathways	R-HSA-177929	364	4	10285	30	ITPR2,LRIG1,FGFR3,ERBB4
2.044e-02	-3.89	bone-Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour	COSMIC cancer mutations	bone-Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour	6023	25	16828	49	SOX5,PTPRZ1,COL5A3,NKAIN3,ABLIM1,MACF1,ITPR2,RORA,SLC4A4,MAML2,RYR3,PREX2,CADM1,CTNND2,NPAS3,ERBB4,LRIG1,SLC1A3,DTNA,ATP1A2,ZBTB20,NCKAP5,ATP13A4,FGFR3,CST3
2.051e-02	-3.89	GLYPICAN	prosite domains	PS01207	6	1	12186	42	GPC5
2.051e-02	-3.89	GAR	prosite domains	PS51460	6	1	12186	42	MACF1
2.060e-02	-3.88	P-type potassium transmembrane transporter activity	molecular function	GO:0008556	8	1	18094	47	ATP1A2
2.060e-02	-3.88	glutamate binding	molecular function	GO:0016595	8	1	18094	47	SLC1A3
2.060e-02	-3.88	sodium ion binding	molecular function	GO:0031402	8	1	18094	47	ATP1A2
2.062e-02	-3.88	Receptor L-domain	gene3d domains	3.80.20.20	7	1	14470	43	ERBB4
2.087e-02	-3.87	adult locomotory behavior	biological process	GO:0008344	81	2	18204	50	PREX2,ATP1A2
2.102e-02	-3.86	PDZ domain binding	molecular function	GO:0030165	86	2	18094	47	DTNA,CADM1
2.105e-02	-3.86	glutamatergic synapse	cellular component	GO:0098978	412	4	19108	49	TNIK,SLC1A2,GPM6A,ERBB4
2.106e-02	-3.86	eye-uveal_tract-malignant_melanoma-spindle	COSMIC cancer mutations	eye-uveal_tract-malignant_melanoma-spindle	363	4	16828	49	PREX2,CTNND2,MACF1,PCDH9
2.106e-02	-3.86	Muscle contraction	REACTOME pathways	R-HSA-397014	204	3	10285	30	ATP1A2,ITPR2,RYR3
2.109e-02	-3.86	HMG20A (high mobility group 20A)	protein interactions	10363	234	3	19454	49	NFIA,DTNA,SOX5
2.117e-02	-3.85	SOX10 (SRY-box transcription factor 10)	protein interactions	6663	89	2	19454	49	TRPS1,NFIA
2.117e-02	-3.85	PLEKHA2 (pleckstrin homology domain containing A2)	protein interactions	59339	89	2	19454	49	AHCYL2,DTNA
2.118e-02	-3.85	kidney-carcinoma-papillary_renal_cell_carcinoma	COSMIC cancer mutations	kidney-carcinoma-papillary_renal_cell_carcinoma	6364	26	16828	49	ATP13A4,FGFR3,ABLIM1,NCKAP5,MACF1,ITPR2,RORA,RFX4,LRIG1,GPC5,NTM,ZBTB20,ATP1A2,NRXN1,CADM1,NFIA,PTPRZ1,ERBB4,PITPNC1,CTNND2,MAML2,RYR3,SLC4A4,SOX5,TNIK,PREX2
2.118e-02	-3.85	papillary_renal_cell_carcinoma	COSMIC cancer mutations	papillary_renal_cell_carcinoma	6364	26	16828	49	LRIG1,NTM,ZBTB20,ATP1A2,ATP13A4,FGFR3,NCKAP5,RFX4,MAML2,RYR3,SLC4A4,PREX2,NRXN1,CADM1,ERBB4,CTNND2,GPC5,ABLIM1,MACF1,ITPR2,RORA,SOX5,TNIK,NFIA,PTPRZ1,PITPNC1
2.123e-02	-3.85	kidney-carcinoma-clear_cell_renal_cell_carcinoma	COSMIC cancer mutations	kidney-carcinoma-clear_cell_renal_cell_carcinoma	13924	46	16828	49	SLC1A3,DTNA,ATP1A2,ZBTB20,LRIG1,CADM1,SLC4A4,NHSL1,RYR3,GPM6A,MACF1,PCDH9,ITPR2,LSAMP,PITPNC1,ZNF98,NFIA,PTPRZ1,CDH20,TNIK,HIF3A,FBXL7,MSI2,NCKAP5,ATP13A4,FGFR3,ACSS1,SLC1A2,QKI,AHCYL2,CTNND2,NPAS3,ERBB4,NRXN1,PARD3B,PREX2,MAML2,RORA,ABLIM1,PTGDS,COL5A3,NKAIN3,SFXN5,GPC5,TRPS1,SOX5
2.123e-02	-3.85	clear_cell_renal_cell_carcinoma	COSMIC cancer mutations	clear_cell_renal_cell_carcinoma	13924	46	16828	49	COL5A3,NKAIN3,SFXN5,GPC5,RORA,ABLIM1,PTGDS,SOX5,TRPS1,ACSS1,MSI2,NCKAP5,ATP13A4,FGFR3,PREX2,MAML2,SLC1A2,AHCYL2,QKI,CTNND2,ERBB4,NPAS3,PARD3B,NRXN1,GPM6A,MACF1,PCDH9,LSAMP,ITPR2,TNIK,HIF3A,FBXL7,PITPNC1,ZNF98,NFIA,PTPRZ1,CDH20,DTNA,SLC1A3,ATP1A2,ZBTB20,LRIG1,SLC4A4,NHSL1,RYR3,CADM1
2.127e-02	-3.85	ConA-like_dom_sf	interpro domains	IPR013320	219	3	18521	50	RYR3,NRXN1,COL5A3
2.140e-02	-3.84	RFX-like	interpro domains	IPR039779	8	1	18521	50	RFX4
2.140e-02	-3.84	Villin_headpiece_dom_sf	interpro domains	IPR036886	8	1	18521	50	ABLIM1
2.140e-02	-3.84	Plakin	interpro domains	IPR043197	8	1	18521	50	MACF1
2.140e-02	-3.84	Villin_headpiece	interpro domains	IPR003128	8	1	18521	50	ABLIM1
2.162e-02	-3.83	CTDSPL (CTD small phosphatase like)	protein interactions	10217	90	2	19454	49	CADM1,DTNA
2.177e-02	-3.83	regulation of synapse structural plasticity	biological process	GO:0051823	8	1	18204	50	CTNNA2
2.177e-02	-3.83	gamma-aminobutyric acid metabolic process	biological process	GO:0009448	8	1	18204	50	SLC1A3
2.177e-02	-3.83	cell proliferation in hindbrain	biological process	GO:0021534	8	1	18204	50	RORA
2.177e-02	-3.83	regulation of germ cell proliferation	biological process	GO:1905936	8	1	18204	50	PTGDS
2.177e-02	-3.83	cell proliferation in external granule layer	biological process	GO:0021924	8	1	18204	50	RORA
2.177e-02	-3.83	regulation of L-glutamate import across plasma membrane	biological process	GO:0002036	8	1	18204	50	ATP1A2
2.177e-02	-3.83	cerebellar granule cell precursor proliferation	biological process	GO:0021930	8	1	18204	50	RORA
2.177e-02	-3.83	ERBB4 signaling pathway	biological process	GO:0038130	8	1	18204	50	ERBB4
2.180e-02	-3.83	CAMK2A (calcium/calmodulin dependent protein kinase II alpha)	protein interactions	815	237	3	19454	49	GPM6A,ITPR2,SOX5
2.185e-02	-3.82	endometrium-carcinoma-serous_carcinoma	COSMIC cancer mutations	endometrium-carcinoma-serous_carcinoma	1442	9	16828	49	TNIK,GPC5,RYR3,SLC4A4,TRPS1,CTNND2,NRXN1,LSAMP,NCKAP5
2.186e-02	-3.82	skin-upper_arm-malignant_melanoma	COSMIC cancer mutations	skin-upper_arm-malignant_melanoma	553	5	16828	49	PREX2,ERBB4,PARD3B,ITPR2,SLC4A4
2.207e-02	-3.81	FOXI1 (forkhead box I1)	protein interactions	2299	91	2	19454	49	NFIA,TRPS1
2.207e-02	-3.81	PTPN21 (protein tyrosine phosphatase non-receptor type 21)	protein interactions	11099	91	2	19454	49	ERBB4,AHCYL2
2.207e-02	-3.81	DGUOK (deoxyguanosine kinase)	protein interactions	1716	91	2	19454	49	NTM,GPM6A
2.219e-02	-3.81	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-T_cell_large_granular_lymphocytic_leukaemia	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-T_cell_large_granular_lymphocytic_leukaemia	79	2	16828	49	MAML2,CADM1
2.224e-02	-3.81	glial cell differentiation	biological process	GO:0010001	219	3	18204	50	NFIA,QKI,PTPRZ1
2.226e-02	-3.80	VHP	pfam domains	PF02209	8	1	17795	50	ABLIM1
2.233e-02	-3.80	regulation of sodium ion transport	biological process	GO:0002028	84	2	18204	50	ATP1A2,NKAIN3
2.233e-02	-3.80	stem cell development	biological process	GO:0048864	84	2	18204	50	ERBB4,MSI2
2.233e-02	-3.80	L-amino acid transport	biological process	GO:0015807	84	2	18204	50	SLC1A3,SLC1A2
2.244e-02	-3.80	Ion channel transport	REACTOME pathways	R-HSA-983712	209	3	10285	30	RYR3,ATP13A4,ATP1A2
2.245e-02	-3.80	Ywhag (tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide)	protein interactions	22628	9	1	19454	49	QKI
2.245e-02	-3.80	NRXN2 (neurexin 2)	protein interactions	9379	9	1	19454	49	MACF1
2.245e-02	-3.80	MUC4 (mucin 4, cell surface associated)	protein interactions	4585	9	1	19454	49	ERBB4
2.245e-02	-3.80	KLB (klotho beta)	protein interactions	152831	9	1	19454	49	FGFR3
2.245e-02	-3.80	Tyw3 (tRNA-yW synthesizing protein 3 homolog (S. cerevisiae))	protein interactions	209584	9	1	19454	49	CTNNA2
2.245e-02	-3.80	GUSBP1 (GUSB pseudogene 1)	protein interactions	728411	9	1	19454	49	FGFR3
2.250e-02	-3.79	response to mechanical stimulus	biological process	GO:0009612	220	3	18204	50	ATP1A2,NRXN1,SLC1A3
2.253e-02	-3.79	SOX9 (SRY-box transcription factor 9)	protein interactions	6662	92	2	19454	49	TRPS1,NFIA
2.253e-02	-3.79	FNTA (farnesyltransferase, CAAX box, subunit alpha)	protein interactions	2339	92	2	19454	49	FGFR3,TNIK
2.253e-02	-3.79	POTEI (POTE ankyrin domain family member I)	protein interactions	653269	92	2	19454	49	FGFR3,DTNA
2.262e-02	-3.79	thyroid	COSMIC cancer mutations	thyroid	9867	36	16828	49	NHSL1,SLC4A4,RYR3,MAML2,PREX2,CADM1,PARD3B,NRXN1,SLC1A2,CTNND2,ERBB4,ACSS1,LRIG1,DTNA,ATP1A2,NCKAP5,ATP13A4,FGFR3,CST3,SOX5,HIF3A,TNIK,CDH20,ZNF98,NFIA,TRPS1,PTPRZ1,GPC5,COL5A3,PCDH9,MACF1,ABLIM1,ITPR2,LSAMP,PTGDS,RORA
2.264e-02	-3.79	GAS2	smart domains	SM00243	6	1	9717	37	MACF1
2.272e-02	-3.78	human chr6q26	chromosome location	human chr6q26	12	1	26134	50	QKI
2.283e-02	-3.78	chondrocyte differentiation	biological process	GO:0002062	85	2	18204	50	FGFR3,SOX5
2.285e-02	-3.78	platelet dense tubular network membrane	cellular component	GO:0031095	9	1	19108	49	ITPR2
2.299e-02	-3.77	ODR4 (odr-4 GPCR localization factor homolog)	protein interactions	54953	93	2	19454	49	LRIG1,GPM6A
2.299e-02	-3.77	MIR19B2 (microRNA 19b-2)	protein interactions	406981	93	2	19454	49	MSI2,QKI
2.299e-02	-3.77	RBM23 (RNA binding motif protein 23)	protein interactions	55147	93	2	19454	49	AHCYL2,QKI
2.299e-02	-3.77	DMRTB1 (DMRT like family B with proline rich C-terminal 1)	protein interactions	63948	93	2	19454	49	MSI2,QKI
2.299e-02	-3.77	TEX11 (testis expressed 11)	protein interactions	56159	93	2	19454	49	QKI,SOX5
2.300e-02	-3.77	-	gene3d domains	2.80.10.50	79	2	14470	43	ITPR2,RYR3
2.306e-02	-3.77	central_nervous_system-chiasm-glioma-astrocytoma_Grade_I	COSMIC cancer mutations	central_nervous_system-chiasm-glioma-astrocytoma_Grade_I	8	1	16828	49	QKI
2.306e-02	-3.77	skin-chest-malignant_melanoma-nodular	COSMIC cancer mutations	skin-chest-malignant_melanoma-nodular	8	1	16828	49	PREX2
2.306e-02	-3.77	urinary_tract-ureter-carcinoma-transitional_cell_carcinoma	COSMIC cancer mutations	urinary_tract-ureter-carcinoma-transitional_cell_carcinoma	8	1	16828	49	FGFR3
2.306e-02	-3.77	junctional	COSMIC cancer mutations	junctional	8	1	16828	49	FGFR3
2.306e-02	-3.77	trichoblastoma	COSMIC cancer mutations	trichoblastoma	8	1	16828	49	FGFR3
2.306e-02	-3.77	cervical_intraepithelial_neoplasia_Grade_I	COSMIC cancer mutations	cervical_intraepithelial_neoplasia_Grade_I	8	1	16828	49	FGFR3
2.306e-02	-3.77	cervix-in_situ_neoplasm-cervical_intraepithelial_neoplasia_Grade_I	COSMIC cancer mutations	cervix-in_situ_neoplasm-cervical_intraepithelial_neoplasia_Grade_I	8	1	16828	49	FGFR3
2.306e-02	-3.77	actinic_keratosis	COSMIC cancer mutations	actinic_keratosis	8	1	16828	49	FGFR3
2.309e-02	-3.77	salivary_gland-parotid-carcinoma-adenoid_cystic_carcinoma	COSMIC cancer mutations	salivary_gland-parotid-carcinoma-adenoid_cystic_carcinoma	561	5	16828	49	ERBB4,TNIK,RYR3,MAML2,FGFR3
2.311e-02	-3.77	Downregulation of ERBB4 signaling	REACTOME pathways	R-HSA-1253288	8	1	10285	30	ERBB4
2.311e-02	-3.77	Release of Hh-Np from the secreting cell	REACTOME pathways	R-HSA-5362798	8	1	10285	30	GPC5
2.323e-02	-3.76	lipid binding	molecular function	GO:0008289	861	6	18094	47	ITPR2,PITPNC1,ATP1A2,RORA,PARD3B,PTGDS
2.325e-02	-3.76	T_cell_large_granular_lymphocytic_leukaemia	COSMIC cancer mutations	T_cell_large_granular_lymphocytic_leukaemia	81	2	16828	49	CADM1,MAML2
2.334e-02	-3.76	protein localization to cell junction	biological process	GO:1902414	86	2	18204	50	NRXN1,ERBB4
2.345e-02	-3.75	WWC1 (WW and C2 domain containing 1)	protein interactions	23286	94	2	19454	49	TNIK,ABLIM1
2.345e-02	-3.75	QSER1 (glutamine and serine rich 1)	protein interactions	79832	94	2	19454	49	SOX5,NFIA
2.345e-02	-3.75	FOXP4 (forkhead box P4)	protein interactions	116113	94	2	19454	49	SOX5,NFIA
2.352e-02	-3.75	organic anion transport	biological process	GO:0015711	398	4	18204	50	SLC4A4,SLC1A2,SLC1A3,SFXN5
2.353e-02	-3.75	Villin headpiece domain	gene3d domains	1.10.950.10	8	1	14470	43	ABLIM1
2.404e-02	-3.73	Band3_cytoplasmic_dom	interpro domains	IPR013769	9	1	18521	50	SLC4A4
2.404e-02	-3.73	DNA-bd_RFX	interpro domains	IPR003150	9	1	18521	50	RFX4
2.404e-02	-3.73	Prot_inh_cystat_CS	interpro domains	IPR018073	9	1	18521	50	CST3
2.405e-02	-3.73	atypical_teratoid-rhabdoid_tumour	COSMIC cancer mutations	atypical_teratoid-rhabdoid_tumour	213	3	16828	49	FGFR3,NCKAP5,PCDH9
2.405e-02	-3.73	central_nervous_system-brain-atypical_teratoid-rhabdoid_tumour	COSMIC cancer mutations	central_nervous_system-brain-atypical_teratoid-rhabdoid_tumour	213	3	16828	49	PCDH9,NCKAP5,FGFR3
2.433e-02	-3.72	Endochondral Ossification	WikiPathways	WP474	65	2	5310	20	FGFR3,SOX5
2.437e-02	-3.71	kidney-carcinoma-renal_cell_carcinoma	COSMIC cancer mutations	kidney-carcinoma-renal_cell_carcinoma	4535	20	16828	49	FGFR3,ITPR2,MACF1,PCDH9,MSI2,RORA,LRIG1,NRXN1,PTPRZ1,ERBB4,TRPS1,QKI,CTNND2,PITPNC1,FBXL7,MAML2,SOX5,HIF3A,TNIK,PREX2
2.437e-02	-3.71	renal_cell_carcinoma	COSMIC cancer mutations	renal_cell_carcinoma	4535	20	16828	49	PREX2,TNIK,SOX5,HIF3A,MAML2,FBXL7,PITPNC1,QKI,CTNND2,TRPS1,PTPRZ1,ERBB4,NRXN1,LRIG1,MSI2,RORA,PCDH9,MACF1,ITPR2,FGFR3
2.446e-02	-3.71	release of sequestered calcium ion into cytosol by sarcoplasmic reticulum	biological process	GO:0014808	9	1	18204	50	RYR3
2.446e-02	-3.71	activated T cell proliferation	biological process	GO:0050798	9	1	18204	50	CADM1
2.446e-02	-3.71	hindbrain radial glia guided cell migration	biological process	GO:0021932	9	1	18204	50	CTNNA2
2.446e-02	-3.71	positive regulation of synapse maturation	biological process	GO:0090129	9	1	18204	50	NRXN1
2.446e-02	-3.71	polyamine transmembrane transport	biological process	GO:1902047	9	1	18204	50	ATP13A4
2.446e-02	-3.71	cyclooxygenase pathway	biological process	GO:0019371	9	1	18204	50	PTGDS
2.446e-02	-3.71	negative regulation of actin nucleation	biological process	GO:0051126	9	1	18204	50	CTNNA2
2.446e-02	-3.71	negative regulation of striated muscle contraction	biological process	GO:0045988	9	1	18204	50	ATP1A2
2.452e-02	-3.71	NCOR2 (nuclear receptor corepressor 2)	protein interactions	9612	248	3	19454	49	SOX5,NFIA,TNIK
2.456e-02	-3.71	membrane	cellular component	GO:0016020	9220	31	19108	49	SLC1A2,NTM,FGFR3,PCDH9,HIF3A,NRXN1,GPM6A,DTNA,CTNND2,LSAMP,RYR3,CTNNA2,PTPRZ1,ITPR2,PTGDS,ATP13A4,PARD3B,LRIG1,CST3,MACF1,TNIK,SLC1A3,SFXN5,ERBB4,GPC5,CADM1,NKAIN3,SLC4A4,PREX2,ATP1A2,CDH20
2.459e-02	-3.71	human chr5p15.1	chromosome location	human chr5p15.1	13	1	26134	50	FBXL7
2.469e-02	-3.70	neck	COSMIC cancer mutations	neck	1231	8	16828	49	CTNND2,ERBB4,FGFR3,ATP13A4,COL5A3,ATP1A2,PREX2,GPC5
2.486e-02	-3.69	SOCS3 (suppressor of cytokine signaling 3)	protein interactions	9021	97	2	19454	49	ERBB4,FGFR3
2.487e-02	-3.69	transcription regulator activity	molecular function	GO:0140110	1937	10	18094	47	TRPS1,HIF3A,ZBTB20,ZNF98,NPAS3,NFIA,RFX4,SOX5,MAML2,RORA
2.491e-02	-3.69	GSG1 (germ cell associated 1)	protein interactions	83445	10	1	19454	49	PITPNC1
2.491e-02	-3.69	Vbp1 (von Hippel-Lindau binding protein 1)	protein interactions	22327	10	1	19454	49	ABLIM1
2.491e-02	-3.69	Hsp90aa1 (heat shock protein 90, alpha (cytosolic), class A member 1)	protein interactions	15519	10	1	19454	49	QKI
2.491e-02	-3.69	BANK1 (B cell scaffold protein with ankyrin repeats 1)	protein interactions	55024	10	1	19454	49	ITPR2
2.491e-02	-3.69	SLC8A2 (solute carrier family 8 member A2)	protein interactions	6543	10	1	19454	49	GPM6A
2.491e-02	-3.69	Mrpl13 (mitochondrial ribosomal protein L13)	protein interactions	68537	10	1	19454	49	QKI
2.491e-02	-3.69	P2rx7 (purinergic receptor P2X 7)	protein interactions	29665	10	1	19454	49	PTPRZ1
2.491e-02	-3.69	EREG (epiregulin)	protein interactions	2069	10	1	19454	49	ERBB4
2.491e-02	-3.69	CALB2 (calbindin 2)	protein interactions	794	10	1	19454	49	GPM6A
2.491e-02	-3.69	PTPRT (protein tyrosine phosphatase receptor type T)	protein interactions	11122	10	1	19454	49	ERBB4
2.495e-02	-3.69	axon	cellular component	GO:0030424	650	5	19108	49	CTNNA2,PCDH9,GPM6A,DTNA,SLC1A2
2.501e-02	-3.69	Band_3_cyto	pfam domains	PF07565	9	1	17795	50	SLC4A4
2.501e-02	-3.69	RFX_DNA_binding	pfam domains	PF02257	9	1	17795	50	RFX4
2.504e-02	-3.69	salivary_gland-carcinoma	COSMIC cancer mutations	salivary_gland-carcinoma	383	4	16828	49	ERBB4,TNIK,FGFR3,MAML2
2.504e-02	-3.69	upper_aerodigestive_tract-mouth-carcinoma-adenoid_cystic_carcinoma	COSMIC cancer mutations	upper_aerodigestive_tract-mouth-carcinoma-adenoid_cystic_carcinoma	383	4	16828	49	MAML2,FGFR3,ERBB4,TNIK
2.504e-02	-3.69	upper_aerodigestive_tract-head_neck-carcinoma-adenoid_cystic_carcinoma	COSMIC cancer mutations	upper_aerodigestive_tract-head_neck-carcinoma-adenoid_cystic_carcinoma	383	4	16828	49	ERBB4,TNIK,FGFR3,MAML2
2.504e-02	-3.69	upper_aerodigestive_tract-lymph_node-carcinoma-adenoid_cystic_carcinoma	COSMIC cancer mutations	upper_aerodigestive_tract-lymph_node-carcinoma-adenoid_cystic_carcinoma	383	4	16828	49	MAML2,FGFR3,TNIK,ERBB4
2.504e-02	-3.69	upper_aerodigestive_tract-carcinoma	COSMIC cancer mutations	upper_aerodigestive_tract-carcinoma	383	4	16828	49	FGFR3,MAML2,ERBB4,TNIK
2.521e-02	-3.68	sarcoplasm	cellular component	GO:0016528	96	2	19108	49	ITPR2,RYR3
2.534e-02	-3.68	MED27 (mediator complex subunit 27)	protein interactions	9442	98	2	19454	49	QKI,SOX5
2.534e-02	-3.68	DNAAF2 (dynein axonemal assembly factor 2)	protein interactions	55172	98	2	19454	49	LSAMP,GPM6A
2.534e-02	-3.68	VAV2 (vav guanine nucleotide exchange factor 2)	protein interactions	7410	98	2	19454	49	ERBB4,NCKAP5
2.536e-02	-3.67	perineuronal net	cellular component	GO:0072534	10	1	19108	49	PTPRZ1
2.539e-02	-3.67	regulation of purine nucleotide metabolic process	biological process	GO:1900542	90	2	18204	50	SLC4A4,ZBTB20
2.555e-02	-3.67	CRX (cone-rod homeobox)	protein interactions	1406	252	3	19454	49	TRPS1,SOX5,NFIA
2.555e-02	-3.67	NCK2 (NCK adaptor protein 2)	protein interactions	8440	252	3	19454	49	NHSL1,ERBB4,TNIK
2.566e-02	-3.66	adrenal_cortical_carcinoma	COSMIC cancer mutations	adrenal_cortical_carcinoma	2256	12	16828	49	NCKAP5,PCDH9,PTPRZ1,SLC1A2,RFX4,CTNND2,LRIG1,MAML2,NHSL1,SOX5,ZBTB20,ATP1A2
2.568e-02	-3.66	polyamine transmembrane transporter activity	molecular function	GO:0015203	10	1	18094	47	ATP13A4
2.568e-02	-3.66	phosphatidylinositol transfer activity	molecular function	GO:0008526	10	1	18094	47	PITPNC1
2.580e-02	-3.66	ATPase-coupled transmembrane transporter activity	molecular function	GO:0042626	96	2	18094	47	ATP1A2,ATP13A4
2.581e-02	-3.66	connective tissue development	biological process	GO:0061448	232	3	18204	50	NFIA,SOX5,FGFR3
2.582e-02	-3.66	ZFHX3 (zinc finger homeobox 3)	protein interactions	463	99	2	19454	49	TRPS1,SOX5
2.582e-02	-3.66	TNKS (tankyrase)	protein interactions	8658	99	2	19454	49	TNIK,PCDH9
2.586e-02	-3.66	parotid	COSMIC cancer mutations	parotid	578	5	16828	49	ERBB4,TNIK,FGFR3,RYR3,MAML2
2.589e-02	-3.65	shoulder	COSMIC cancer mutations	shoulder	387	4	16828	49	PREX2,ERBB4,MACF1,FGFR3
2.591e-02	-3.65	Bowen_disease	COSMIC cancer mutations	Bowen_disease	9	1	16828	49	FGFR3
2.591e-02	-3.65	skin-chest-malignant_melanoma-superficial_spreading	COSMIC cancer mutations	skin-chest-malignant_melanoma-superficial_spreading	9	1	16828	49	PREX2
2.591e-02	-3.65	skin-other-seborrhoeic_keratosis	COSMIC cancer mutations	skin-other-seborrhoeic_keratosis	9	1	16828	49	FGFR3
2.591e-02	-3.65	in_situ_epithelial_neoplasm	COSMIC cancer mutations	in_situ_epithelial_neoplasm	9	1	16828	49	FGFR3
2.591e-02	-3.65	compound	COSMIC cancer mutations	compound	9	1	16828	49	FGFR3
2.591e-02	-3.65	epidermal_nevus	COSMIC cancer mutations	epidermal_nevus	9	1	16828	49	FGFR3
2.591e-02	-3.65	ovary-low_malignant_potential_(borderline)_tumour-Brenner_tumour	COSMIC cancer mutations	ovary-low_malignant_potential_(borderline)_tumour-Brenner_tumour	9	1	16828	49	FGFR3
2.591e-02	-3.65	skin-benign_melanocytic_nevus-congenital	COSMIC cancer mutations	skin-benign_melanocytic_nevus-congenital	9	1	16828	49	FGFR3
2.591e-02	-3.65	skin-upper_leg-malignant_melanoma-superficial_spreading	COSMIC cancer mutations	skin-upper_leg-malignant_melanoma-superficial_spreading	9	1	16828	49	PREX2
2.592e-02	-3.65	regulation of nucleotide metabolic process	biological process	GO:0006140	91	2	18204	50	ZBTB20,SLC4A4
2.621e-02	-3.64	oesophagus-carcinoma-adenocarcinoma	COSMIC cancer mutations	oesophagus-carcinoma-adenocarcinoma	13112	44	16828	49	ATP1A2,SLC1A3,ZBTB20,NTM,LRIG1,CADM1,NHSL1,SLC4A4,RYR3,GPM6A,ITPR2,LSAMP,PCDH9,MACF1,ZNF98,PTPRZ1,CDH20,TNIK,HIF3A,FBXL7,RFX4,CST3,NCKAP5,FGFR3,ATP13A4,ACSS1,CTNND2,QKI,AHCYL2,SLC1A2,NPAS3,ERBB4,PARD3B,NRXN1,PREX2,MAML2,RORA,PTGDS,COL5A3,NKAIN3,SFXN5,GPC5,TRPS1,SOX5
2.630e-02	-3.64	SFN (stratifin)	protein interactions	2810	671	5	19454	49	ABLIM1,MACF1,NFIA,TNIK,PARD3B
2.630e-02	-3.64	APBA1 (amyloid beta precursor protein binding family A member 1)	protein interactions	320	100	2	19454	49	ABLIM1,NRXN1
2.630e-02	-3.64	ATP4A (ATPase H+/K+ transporting subunit alpha)	protein interactions	495	100	2	19454	49	GPM6A,ATP1A2
2.634e-02	-3.64	DYNLL2 (dynein light chain LC8-type 2)	protein interactions	140735	255	3	19454	49	NHSL1,TRPS1,NFIA
2.636e-02	-3.64	PLEC	smart domains	SM00250	7	1	9717	37	MACF1
2.637e-02	-3.64	intracellular signaling cassette	biological process	GO:0141124	837	6	18204	50	ITPR2,TNIK,RYR3,ATP1A2,FGFR3,PREX2
2.639e-02	-3.63	PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling	REACTOME pathways	R-HSA-6811558	87	2	10285	30	FGFR3,ERBB4
2.646e-02	-3.63	human chr2p13.2	chromosome location	human chr2p13.2	14	1	26134	50	SFXN5
2.646e-02	-3.63	human chr2p16.3	chromosome location	human chr2p16.3	14	1	26134	50	NRXN1
2.668e-02	-3.62	PAS_fold_3	interpro domains	IPR013655	10	1	18521	50	NPAS3
2.668e-02	-3.62	HCO3_transpt_euk	interpro domains	IPR003020	10	1	18521	50	SLC4A4
2.668e-02	-3.62	PTrfase/Anion_transptr	interpro domains	IPR016152	10	1	18521	50	SLC4A4
2.668e-02	-3.62	HCO3_transpt-like_TM_dom	interpro domains	IPR011531	10	1	18521	50	SLC4A4
2.679e-02	-3.62	CLEC4A (C-type lectin domain family 4 member A)	protein interactions	50856	101	2	19454	49	CTNNA2,FGFR3
2.679e-02	-3.62	ILKAP (ILK associated serine/threonine phosphatase)	protein interactions	80895	101	2	19454	49	FGFR3,ERBB4
2.690e-02	-3.62	chemical synaptic transmission	biological process	GO:0007268	415	4	18204	50	NRXN1,SLC1A2,SLC1A3,DTNA
2.690e-02	-3.62	anterograde trans-synaptic signaling	biological process	GO:0098916	415	4	18204	50	SLC1A2,SLC1A3,NRXN1,DTNA
2.697e-02	-3.61	FLOT1 (flotillin 1)	protein interactions	10211	453	4	19454	49	SOX5,MACF1,ABLIM1,DTNA
2.714e-02	-3.61	postsynaptic density assembly	biological process	GO:0097107	10	1	18204	50	NRXN1
2.714e-02	-3.61	release of sequestered calcium ion into cytosol by endoplasmic reticulum	biological process	GO:1903514	10	1	18204	50	RYR3
2.714e-02	-3.61	establishment of centrosome localization	biological process	GO:0051660	10	1	18204	50	PARD3B
2.714e-02	-3.61	regulation of mesenchymal stem cell differentiation	biological process	GO:2000739	10	1	18204	50	SOX5
2.714e-02	-3.61	otolith development	biological process	GO:0048840	10	1	18204	50	LRIG1
2.714e-02	-3.61	neuronal action potential propagation	biological process	GO:0019227	10	1	18204	50	ATP1A2
2.714e-02	-3.61	postsynaptic membrane assembly	biological process	GO:0097104	10	1	18204	50	NRXN1
2.714e-02	-3.61	learned vocalization behavior or vocal learning	biological process	GO:0098598	10	1	18204	50	NRXN1
2.714e-02	-3.61	mitochondrial fragmentation involved in apoptotic process	biological process	GO:0043653	10	1	18204	50	ERBB4
2.714e-02	-3.61	action potential propagation	biological process	GO:0098870	10	1	18204	50	ATP1A2
2.719e-02	-3.60	Tyr_kinase_AS	interpro domains	IPR008266	95	2	18521	50	ERBB4,FGFR3
2.724e-02	-3.60	GATAZNFINGER	prints domains	PR00619	8	1	5227	18	TRPS1
2.724e-02	-3.60	LIPOCALIN	prints domains	PR00179	8	1	5227	18	PTGDS
2.725e-02	-3.60	GATA_ZN_FINGER_1	prosite domains	PS00344	8	1	12186	42	TRPS1
2.725e-02	-3.60	HP	prosite domains	PS51089	8	1	12186	42	ABLIM1
2.728e-02	-3.60	MIR7-1 (microRNA 7-1)	protein interactions	407043	102	2	19454	49	MSI2,QKI
2.735e-02	-3.60	LCK (LCK proto-oncogene, Src family tyrosine kinase)	protein interactions	3932	455	4	19454	49	MACF1,CTNND2,ERBB4,DTNA
2.737e-02	-3.60	Cobll1 (Cobl-like 1)	protein interactions	319876	11	1	19454	49	ABLIM1
2.737e-02	-3.60	GAL3ST1 (galactose-3-O-sulfotransferase 1)	protein interactions	9514	11	1	19454	49	LRIG1
2.737e-02	-3.60	Batf3 (basic leucine zipper transcription factor, ATF-like 3)	protein interactions	381319	11	1	19454	49	MACF1
2.737e-02	-3.60	IL7 (interleukin 7)	protein interactions	3574	11	1	19454	49	QKI
2.737e-02	-3.60	Gtf2e2 (general transcription factor II E, polypeptide 2 (beta subunit))	protein interactions	68153	11	1	19454	49	NHSL1
2.737e-02	-3.60	DAZ1 (deleted in azoospermia 1)	protein interactions	1617	11	1	19454	49	QKI
2.737e-02	-3.60	SYTL1 (synaptotagmin like 1)	protein interactions	84958	11	1	19454	49	NRXN1
2.737e-02	-3.60	IRAG1 (inositol 1,4,5-triphosphate receptor associated 1)	protein interactions	10335	11	1	19454	49	ITPR2
2.737e-02	-3.60	Wipi2 (WD repeat domain, phosphoinositide interacting 2)	protein interactions	74781	11	1	19454	49	MACF1
2.737e-02	-3.60	SYN3 (synapsin III)	protein interactions	8224	11	1	19454	49	GPM6A
2.737e-02	-3.60	CCDC17 (coiled-coil domain containing 17)	protein interactions	149483	11	1	19454	49	FGFR3
2.737e-02	-3.60	AQP5 (aquaporin 5)	protein interactions	362	11	1	19454	49	ATP1A2
2.737e-02	-3.60	PTGDR (prostaglandin D2 receptor)	protein interactions	5729	11	1	19454	49	PTGDS
2.741e-02	-3.60	uveal_tract	COSMIC cancer mutations	uveal_tract	587	5	16828	49	FGFR3,MACF1,PCDH9,PREX2,CTNND2
2.752e-02	-3.59	Protein digestion and absorption	KEGG pathways	ko04974	89	2	7161	21	ATP1A2,COL5A3
2.752e-02	-3.59	Protein digestion and absorption	KEGG pathways	hsa04974	89	2	7161	21	ATP1A2,COL5A3
2.756e-02	-3.59	muscle contraction	biological process	GO:0006936	238	3	18204	50	DTNA,ATP1A2,RYR3
2.756e-02	-3.59	protein localization to cell periphery	biological process	GO:1990778	238	3	18204	50	TNIK,MACF1,ERBB4
2.775e-02	-3.58	PAS_3	pfam domains	PF08447	10	1	17795	50	NPAS3
2.775e-02	-3.58	HCO3_cotransp	pfam domains	PF00955	10	1	17795	50	SLC4A4
2.782e-02	-3.58	amino acid transmembrane transporter activity	molecular function	GO:0015171	100	2	18094	47	SLC1A2,SLC1A3
2.786e-02	-3.58	platelet dense tubular network	cellular component	GO:0031094	11	1	19108	49	ITPR2
2.786e-02	-3.58	perisynaptic extracellular matrix	cellular component	GO:0098966	11	1	19108	49	PTPRZ1
2.800e-02	-3.58	CTNNB1 (catenin beta 1)	protein interactions	1499	926	6	19454	49	PARD3B,CTNNA2,PTPRZ1,NHSL1,DTNA,CTNND2
2.807e-02	-3.57	calcium ion transmembrane import into cytosol	biological process	GO:0097553	95	2	18204	50	RYR3,ITPR2
2.811e-02	-3.57	PI3K/AKT Signaling in Cancer	REACTOME pathways	R-HSA-2219528	90	2	10285	30	ERBB4,FGFR3
2.814e-02	-3.57	basolateral plasma membrane	cellular component	GO:0016323	257	3	19108	49	CADM1,SLC4A4,ERBB4
2.821e-02	-3.57	sulfur amino acid transmembrane transporter activity	molecular function	GO:0000099	11	1	18094	47	SLC1A2
2.821e-02	-3.57	acetylcholine receptor binding	molecular function	GO:0033130	11	1	18094	47	NRXN1
2.832e-02	-3.56	human chr8q12.3	chromosome location	human chr8q12.3	15	1	26134	50	NKAIN3
2.842e-02	-3.56	Signaling by the B Cell Receptor (BCR)	REACTOME pathways	R-HSA-983705	229	3	10285	30	FGFR3,ERBB4,ITPR2
2.849e-02	-3.56	protein binding	molecular function	GO:0005515	13983	42	18094	47	DTNA,MSI2,SLC1A2,TNIK,SLC1A3,QKI,CDH20,RYR3,ABLIM1,GPC5,GPM6A,PTGDS,MAML2,AHCYL2,ERBB4,FGFR3,CADM1,CST3,ACSS1,RFX4,PITPNC1,SOX5,NTM,ATP1A2,RORA,CTNND2,LRIG1,FBXL7,HIF3A,COL5A3,PTPRZ1,NPAS3,NFIA,ITPR2,SLC4A4,LSAMP,PARD3B,SFXN5,TRPS1,MACF1,CTNNA2,NRXN1
2.865e-02	-3.55	urinary_tract-bladder-carcinoma	COSMIC cancer mutations	urinary_tract-bladder-carcinoma	14050	46	16828	49	MAML2,PREX2,PARD3B,NRXN1,ERBB4,NPAS3,SLC1A2,CTNND2,QKI,AHCYL2,ACSS1,ATP13A4,FGFR3,NCKAP5,MSI2,RFX4,SOX5,TRPS1,GPC5,SFXN5,COL5A3,PTGDS,ABLIM1,RORA,RYR3,SLC4A4,CADM1,LRIG1,NTM,ZBTB20,ATP1A2,DTNA,SLC1A3,FBXL7,HIF3A,TNIK,CDH20,NFIA,PTPRZ1,PITPNC1,ZNF98,MACF1,PCDH9,LSAMP,ITPR2,GPM6A
2.865e-02	-3.55	soft_tissue-striated_muscle-rhabdomyosarcoma	COSMIC cancer mutations	soft_tissue-striated_muscle-rhabdomyosarcoma	594	5	16828	49	MACF1,COL5A3,CTNND2,PREX2,TRPS1
2.875e-02	-3.55	lung-carcinoma-pleomorphic_carcinoma	COSMIC cancer mutations	lung-carcinoma-pleomorphic_carcinoma	10	1	16828	49	FGFR3
2.875e-02	-3.55	cervical_intraepithelial_neoplasia_Grade_III	COSMIC cancer mutations	cervical_intraepithelial_neoplasia_Grade_III	10	1	16828	49	FGFR3
2.875e-02	-3.55	skin-back-malignant_melanoma-nodular	COSMIC cancer mutations	skin-back-malignant_melanoma-nodular	10	1	16828	49	PREX2
2.875e-02	-3.55	chiasm	COSMIC cancer mutations	chiasm	10	1	16828	49	QKI
2.875e-02	-3.55	cervix-in_situ_neoplasm-cervical_intraepithelial_neoplasia_Grade_III	COSMIC cancer mutations	cervix-in_situ_neoplasm-cervical_intraepithelial_neoplasia_Grade_III	10	1	16828	49	FGFR3
2.875e-02	-3.55	renal_cell_carcinoma_unclassified	COSMIC cancer mutations	renal_cell_carcinoma_unclassified	10	1	16828	49	FGFR3
2.875e-02	-3.55	intradermal	COSMIC cancer mutations	intradermal	10	1	16828	49	FGFR3
2.875e-02	-3.55	kidney-carcinoma-renal_cell_carcinoma_unclassified	COSMIC cancer mutations	kidney-carcinoma-renal_cell_carcinoma_unclassified	10	1	16828	49	FGFR3
2.878e-02	-3.55	BEND3 (BEN domain containing 3)	protein interactions	57673	105	2	19454	49	TNIK,TRPS1
2.878e-02	-3.55	IRF2BP2 (interferon regulatory factor 2 binding protein 2)	protein interactions	359948	105	2	19454	49	NFIA,ERBB4
2.880e-02	-3.55	PI3K events in ERBB4 signaling	REACTOME pathways	R-HSA-1250342	10	1	10285	30	ERBB4
2.880e-02	-3.55	Signaling by FGFR3 fusions in cancer	REACTOME pathways	R-HSA-8853334	10	1	10285	30	FGFR3
2.896e-02	-3.54	Methionine degradation	KEGG pathways	M00035	10	1	7161	21	AHCYL2
2.896e-02	-3.54	Methionine degradation	KEGG pathways	hsa_M00035	10	1	7161	21	AHCYL2
2.917e-02	-3.53	nerve development	biological process	GO:0021675	97	2	18204	50	SLC1A3,LRIG1
2.917e-02	-3.53	amino acid transmembrane transport	biological process	GO:0003333	97	2	18204	50	SLC1A3,SLC1A2
2.927e-02	-3.53	Post-translational modification: synthesis of GPI-anchored proteins	REACTOME pathways	R-HSA-163125	92	2	10285	30	NTM,LSAMP
2.929e-02	-3.53	USP30 (ubiquitin specific peptidase 30)	protein interactions	84749	106	2	19454	49	FGFR3,QKI
2.931e-02	-3.53	Fib_collagen_C	interpro domains	IPR000885	11	1	18521	50	COL5A3
2.933e-02	-3.53	Helical hairpin bin	gene3d domains	1.10.287.570	10	1	14470	43	SLC4A4
2.972e-02	-3.52	kidney-carcinoma	COSMIC cancer mutations	kidney-carcinoma	3720	17	16828	49	RORA,MSI2,ITPR2,FGFR3,LRIG1,CTNND2,QKI,PITPNC1,PTPRZ1,ERBB4,TRPS1,TNIK,PREX2,SOX5,HIF3A,FBXL7,MAML2
2.981e-02	-3.51	lactone metabolic process	biological process	GO:1901334	11	1	18204	50	ATP1A2
2.981e-02	-3.51	establishment or maintenance of transmembrane electrochemical gradient	biological process	GO:0010248	11	1	18204	50	ATP1A2
2.981e-02	-3.51	intracellular mRNA localization	biological process	GO:0008298	11	1	18204	50	QKI
2.981e-02	-3.51	polyamine transport	biological process	GO:0015846	11	1	18204	50	ATP13A4
2.981e-02	-3.51	L-ascorbic acid metabolic process	biological process	GO:0019852	11	1	18204	50	ATP1A2
2.981e-02	-3.51	cellular response to caffeine	biological process	GO:0071313	11	1	18204	50	RYR3
2.982e-02	-3.51	CA4 (carbonic anhydrase 4)	protein interactions	762	12	1	19454	49	SLC4A4
2.982e-02	-3.51	IL15 (interleukin 15)	protein interactions	3600	12	1	19454	49	LRIG1
2.982e-02	-3.51	PTPN20 (protein tyrosine phosphatase non-receptor type 20)	protein interactions	26095	12	1	19454	49	ERBB4
2.982e-02	-3.51	SMIM20 (small integral membrane protein 20)	protein interactions	389203	12	1	19454	49	ERBB4
2.982e-02	-3.51	LMP-1 (latent membrane protein LMP-1)	protein interactions	3783750	12	1	19454	49	TNIK
2.982e-02	-3.51	ART4 (ADP-ribosyltransferase 4 (inactive) (Dombrock blood group))	protein interactions	420	12	1	19454	49	GPM6A
2.999e-02	-3.51	regulation of synapse organization	biological process	GO:0050807	246	3	18204	50	GPM6A,CTNNA2,NRXN1
2.999e-02	-3.51	positive regulation of neurogenesis	biological process	GO:0050769	246	3	18204	50	QKI,MACF1,PTPRZ1
3.007e-02	-3.50	VHP	smart domains	SM00153	8	1	9717	37	ABLIM1
3.012e-02	-3.50	ATXN1 (ataxin 1)	protein interactions	6310	469	4	19454	49	QKI,NFIA,CST3,PTGDS
3.031e-02	-3.50	PAX8 (paired box 8)	protein interactions	7849	108	2	19454	49	TRPS1,NFIA
3.031e-02	-3.50	CAMKV (CaM kinase like vesicle associated)	protein interactions	79012	108	2	19454	49	AHCYL2,GPM6A
3.034e-02	-3.50	response to wounding	biological process	GO:0009611	431	4	18204	50	NFIA,MACF1,SLC1A3,SLC1A2
3.034e-02	-3.50	trans-synaptic signaling	biological process	GO:0099537	431	4	18204	50	NRXN1,SLC1A2,SLC1A3,DTNA
3.034e-02	-3.50	g-Secretase Mediated ErbB4 Signalling Pathway	SMPDB pathways	SMP0089975	7	1	1369	6	ERBB4
3.034e-02	-3.50	Ethanol Degradation	SMPDB pathways	SMP0000449	7	1	1369	6	ACSS1
3.035e-02	-3.49	synapse-associated extracellular matrix	cellular component	GO:0099535	12	1	19108	49	PTPRZ1
3.035e-02	-3.49	fibrillar collagen trimer	cellular component	GO:0005583	12	1	19108	49	COL5A3
3.035e-02	-3.49	banded collagen fibril	cellular component	GO:0098643	12	1	19108	49	COL5A3
3.035e-02	-3.49	sodium:potassium-exchanging ATPase complex	cellular component	GO:0005890	12	1	19108	49	ATP1A2
3.046e-02	-3.49	Negative regulation of the PI3K/AKT network	REACTOME pathways	R-HSA-199418	94	2	10285	30	FGFR3,ERBB4
3.049e-02	-3.49	COLFI	pfam domains	PF01410	11	1	17795	50	COL5A3
3.049e-02	-3.49	PAS_11	pfam domains	PF14598	11	1	17795	50	HIF3A
3.049e-02	-3.49	LRRCT	pfam domains	PF01463	11	1	17795	50	LRIG1
3.060e-02	-3.49	CYSTATIN	prosite domains	PS00287	9	1	12186	42	CST3
3.060e-02	-3.49	RFX_DBD	prosite domains	PS51526	9	1	12186	42	RFX4
3.063e-02	-3.49	spleen	COSMIC cancer mutations	spleen	408	4	16828	49	TNIK,PTPRZ1,PARD3B,NTM
3.074e-02	-3.48	inositol 1,4,5 trisphosphate binding	molecular function	GO:0070679	12	1	18094	47	ITPR2
3.079e-02	-3.48	inorganic ion homeostasis	biological process	GO:0098771	433	4	18204	50	ATP13A4,SLC1A3,RYR3,ATP1A2
3.083e-02	-3.48	MIR34B (microRNA 34b)	protein interactions	407041	109	2	19454	49	MSI2,QKI
3.087e-02	-3.48	eye	COSMIC cancer mutations	eye	606	5	16828	49	PREX2,CTNND2,FGFR3,PCDH9,MACF1
3.106e-02	-3.47	RDX (radixin)	protein interactions	5962	272	3	19454	49	MACF1,FGFR3,ABLIM1
3.139e-02	-3.46	calcium ion binding	molecular function	GO:0005509	683	5	18094	47	PCDH9,ITPR2,MACF1,RYR3,NRXN1
3.149e-02	-3.46	RNA polymerase II cis-regulatory region sequence-specific DNA binding	molecular function	GO:0000978	1180	7	18094	47	RORA,SOX5,HIF3A,ZBTB20,ZNF98,NFIA,RFX4
3.151e-02	-3.46	steroid binding	molecular function	GO:0005496	107	2	18094	47	RORA,ATP1A2
3.157e-02	-3.46	calcium ion transport	biological process	GO:0006816	251	3	18204	50	ITPR2,GPM6A,RYR3
3.158e-02	-3.46	skin-scalp-carcinoma-basal_cell_carcinoma	COSMIC cancer mutations	skin-scalp-carcinoma-basal_cell_carcinoma	11	1	16828	49	FGFR3
3.158e-02	-3.46	skin-neck-carcinoma-basal_cell_carcinoma	COSMIC cancer mutations	skin-neck-carcinoma-basal_cell_carcinoma	11	1	16828	49	FGFR3
3.158e-02	-3.46	skin-back-malignant_melanoma-superficial_spreading	COSMIC cancer mutations	skin-back-malignant_melanoma-superficial_spreading	11	1	16828	49	PREX2
3.158e-02	-3.46	prostate-hyperplasia	COSMIC cancer mutations	prostate-hyperplasia	11	1	16828	49	FGFR3
3.158e-02	-3.46	kidney-other-oncocytoma	COSMIC cancer mutations	kidney-other-oncocytoma	11	1	16828	49	FGFR3
3.158e-02	-3.46	seborrhoeic_keratosis	COSMIC cancer mutations	seborrhoeic_keratosis	11	1	16828	49	FGFR3
3.158e-02	-3.46	congenital	COSMIC cancer mutations	congenital	11	1	16828	49	FGFR3
3.158e-02	-3.46	oncocytoma	COSMIC cancer mutations	oncocytoma	11	1	16828	49	FGFR3
3.158e-02	-3.46	pleomorphic_carcinoma	COSMIC cancer mutations	pleomorphic_carcinoma	11	1	16828	49	FGFR3
3.158e-02	-3.46	skin-hand-malignant_melanoma-acral_lentiginous	COSMIC cancer mutations	skin-hand-malignant_melanoma-acral_lentiginous	11	1	16828	49	PREX2
3.189e-02	-3.45	regulation of synapse structure or activity	biological process	GO:0050803	252	3	18204	50	GPM6A,CTNNA2,NRXN1
3.193e-02	-3.44	Lipocalin	interpro domains	IPR002345	12	1	18521	50	PTGDS
3.193e-02	-3.44	Lipocalin_CS	interpro domains	IPR022272	12	1	18521	50	PTGDS
3.193e-02	-3.44	MAD_homology1_Dwarfin-type	interpro domains	IPR003619	12	1	18521	50	NFIA
3.226e-02	-3.43	Rbm47 (RNA binding motif protein 47)	protein interactions	245945	13	1	19454	49	QKI
3.226e-02	-3.43	TBCC (tubulin folding cofactor C)	protein interactions	6903	13	1	19454	49	NTM
3.226e-02	-3.43	PCDHA2 (protocadherin alpha 2)	protein interactions	56146	13	1	19454	49	NFIA
3.226e-02	-3.43	RAB3C (RAB3C, member RAS oncogene family)	protein interactions	115827	13	1	19454	49	GPM6A
3.226e-02	-3.43	MYO16 (myosin XVI)	protein interactions	23026	13	1	19454	49	NRXN1
3.233e-02	-3.43	ACTB (actin beta)	protein interactions	60	958	6	19454	49	SFXN5,AHCYL2,DTNA,NHSL1,MACF1,ABLIM1
3.240e-02	-3.43	EF-hand-dom_pair	interpro domains	IPR011992	258	3	18521	50	RYR3,DTNA,MACF1
3.241e-02	-3.43	CEP170P1 (centrosomal protein 170 pseudogene 1)	protein interactions	645455	112	2	19454	49	MACF1,TRPS1
3.241e-02	-3.43	EDA (ectodysplasin A)	protein interactions	1896	112	2	19454	49	ERBB4,GPM6A
3.248e-02	-3.43	microglia differentiation	biological process	GO:0014004	12	1	18204	50	QKI
3.248e-02	-3.43	sulfur amino acid transport	biological process	GO:0000101	12	1	18204	50	SLC1A2
3.248e-02	-3.43	regulation of blood vessel remodeling	biological process	GO:0060312	12	1	18204	50	CST3
3.248e-02	-3.43	negative regulation of collagen metabolic process	biological process	GO:0010713	12	1	18204	50	CST3
3.302e-02	-3.41	endoplasmic reticulum	cellular component	GO:0005783	2051	10	19108	49	NRXN1,ITPR2,CST3,FGFR3,AHCYL2,RYR3,ATP13A4,COL5A3,ATP1A2,PTGDS
3.310e-02	-3.41	bladder	COSMIC cancer mutations	bladder	14112	46	16828	49	CDH20,ZNF98,PITPNC1,PTPRZ1,NFIA,HIF3A,FBXL7,TNIK,LSAMP,ITPR2,PCDH9,MACF1,GPM6A,CADM1,SLC4A4,RYR3,NTM,LRIG1,SLC1A3,ATP1A2,DTNA,ZBTB20,TRPS1,SOX5,ABLIM1,PTGDS,RORA,SFXN5,GPC5,COL5A3,NRXN1,PARD3B,AHCYL2,CTNND2,QKI,SLC1A2,NPAS3,ERBB4,MAML2,PREX2,NCKAP5,FGFR3,ATP13A4,RFX4,MSI2,ACSS1
3.310e-02	-3.41	urinary_tract	COSMIC cancer mutations	urinary_tract	14112	46	16828	49	NTM,LRIG1,SLC1A3,DTNA,ATP1A2,ZBTB20,SLC4A4,RYR3,CADM1,MACF1,PCDH9,LSAMP,ITPR2,GPM6A,HIF3A,FBXL7,TNIK,CDH20,PITPNC1,ZNF98,NFIA,PTPRZ1,ACSS1,NCKAP5,ATP13A4,FGFR3,RFX4,MSI2,MAML2,PREX2,PARD3B,NRXN1,SLC1A2,CTNND2,AHCYL2,QKI,NPAS3,ERBB4,SFXN5,GPC5,COL5A3,ABLIM1,PTGDS,RORA,SOX5,TRPS1
3.321e-02	-3.40	MH1	pfam domains	PF03165	12	1	17795	50	NFIA
3.326e-02	-3.40	monoatomic cation:bicarbonate symporter activity	molecular function	GO:0140410	13	1	18094	47	SLC4A4
3.326e-02	-3.40	potassium ion binding	molecular function	GO:0030955	13	1	18094	47	ATP1A2
3.334e-02	-3.40	YWHAB (tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein beta)	protein interactions	7529	965	6	19454	49	PARD3B,FGFR3,NHSL1,MACF1,PITPNC1,ABLIM1
3.342e-02	-3.40	EV release from cardiac cells and their functional effects	WikiPathways	WP3297	9	1	5310	20	ERBB4
3.351e-02	-3.40	cell fate commitment	biological process	GO:0045165	257	3	18204	50	ERBB4,SOX5,NFIA
3.389e-02	-3.38	human chr7q31.32	chromosome location	human chr7q31.32	18	1	26134	50	PTPRZ1
3.389e-02	-3.38	human chr18q21.33	chromosome location	human chr18q21.33	18	1	26134	50	CDH20
3.394e-02	-3.38	HCO3TRNSPORT	prints domains	PR01231	10	1	5227	18	SLC4A4
3.401e-02	-3.38	CAV1 (caveolin 1)	protein interactions	857	719	5	19454	49	MACF1,SLC1A3,AHCYL2,DTNA,TNIK
3.401e-02	-3.38	TBXT (T-box transcription factor T)	protein interactions	6862	115	2	19454	49	NFIA,TRPS1
3.418e-02	-3.38	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-acute_lymphoblastic_leukaemia	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-acute_lymphoblastic_leukaemia	2081	11	16828	49	ATP1A2,DTNA,PREX2,TNIK,SLC4A4,SOX5,TRPS1,NFIA,PTPRZ1,ERBB4,FGFR3
3.427e-02	-3.37	adrenal_gland	COSMIC cancer mutations	adrenal_gland	2628	13	16828	49	MAML2,SOX5,NHSL1,PTPRZ1,CTNND2,SLC1A2,ZBTB20,ATP1A2,LRIG1,RFX4,FGFR3,PCDH9,NCKAP5
3.440e-02	-3.37	skin-benign_melanocytic_nevus	COSMIC cancer mutations	skin-benign_melanocytic_nevus	12	1	16828	49	FGFR3
3.440e-02	-3.37	skin-abdomen-malignant_melanoma-nodular	COSMIC cancer mutations	skin-abdomen-malignant_melanoma-nodular	12	1	16828	49	PREX2
3.440e-02	-3.37	central_nervous_system-fourth_ventricle-glioma-astrocytoma_Grade_I	COSMIC cancer mutations	central_nervous_system-fourth_ventricle-glioma-astrocytoma_Grade_I	12	1	16828	49	QKI
3.440e-02	-3.37	skin-face-carcinoma-basal_cell_carcinoma	COSMIC cancer mutations	skin-face-carcinoma-basal_cell_carcinoma	12	1	16828	49	FGFR3
3.440e-02	-3.37	cervix-carcinoma-mixed_adenosquamous_carcinoma	COSMIC cancer mutations	cervix-carcinoma-mixed_adenosquamous_carcinoma	12	1	16828	49	FGFR3
3.446e-02	-3.37	Signaling by activated point mutants of FGFR3	REACTOME pathways	R-HSA-1839130	12	1	10285	30	FGFR3
3.446e-02	-3.37	Defective EXT1 causes exostoses 1, TRPS2 and CHDS	REACTOME pathways	R-HSA-3656253	12	1	10285	30	GPC5
3.446e-02	-3.37	Regulation of gene expression by Hypoxia-inducible Factor	REACTOME pathways	R-HSA-1234158	12	1	10285	30	HIF3A
3.446e-02	-3.37	Defective EXT2 causes exostoses 2	REACTOME pathways	R-HSA-3656237	12	1	10285	30	GPC5
3.446e-02	-3.37	Ethanol oxidation	REACTOME pathways	R-HSA-71384	12	1	10285	30	ACSS1
3.446e-02	-3.37	FGFR3 mutant receptor activation	REACTOME pathways	R-HSA-2033514	12	1	10285	30	FGFR3
3.448e-02	-3.37	cis-regulatory region sequence-specific DNA binding	molecular function	GO:0000987	1203	7	18094	47	SOX5,RORA,HIF3A,ZNF98,ZBTB20,NFIA,RFX4
3.462e-02	-3.36	Bile Acid Indirect Signalling Pathway	SMPDB pathways	SMP0086851	8	1	1369	6	FGFR3
3.470e-02	-3.36	SLC1A2 (solute carrier family 1 member 2)	protein interactions	6506	14	1	19454	49	SLC1A2
3.470e-02	-3.36	DACT2 (dishevelled binding antagonist of beta catenin 2)	protein interactions	168002	14	1	19454	49	ZBTB20
3.470e-02	-3.36	SYT5 (synaptotagmin 5)	protein interactions	6861	14	1	19454	49	NRXN1
3.470e-02	-3.36	FGF7 (fibroblast growth factor 7)	protein interactions	2252	14	1	19454	49	FGFR3
3.470e-02	-3.36	PLXNA4 (plexin A4)	protein interactions	91584	14	1	19454	49	GPM6A
3.470e-02	-3.36	Asap1 (ArfGAP with SH3 domain, ankyrin repeat and PH domain1)	protein interactions	13196	14	1	19454	49	MACF1
3.470e-02	-3.36	MB (myoglobin)	protein interactions	4151	14	1	19454	49	MAML2
3.470e-02	-3.36	CTSO (cathepsin O)	protein interactions	1519	14	1	19454	49	CST3
3.470e-02	-3.36	VSX2 (visual system homeobox 2)	protein interactions	338917	14	1	19454	49	AHCYL2
3.479e-02	-3.36	phosphatidylinositol binding	molecular function	GO:0035091	276	3	18094	47	ITPR2,PITPNC1,PARD3B
3.481e-02	-3.36	Disease	REACTOME pathways	R-HSA-1643685	858	6	10285	30	QKI,MACF1,FGFR3,ERBB4,GPC5,MAML2
3.484e-02	-3.36	cell-cell adhesion via plasma-membrane adhesion molecules	biological process	GO:0098742	261	3	18204	50	CADM1,CDH20,PCDH9
3.500e-02	-3.35	Cadherin_CS	interpro domains	IPR020894	109	2	18521	50	PCDH9,CDH20
3.500e-02	-3.35	Ion_trans_dom	interpro domains	IPR005821	109	2	18521	50	RYR3,ITPR2
3.510e-02	-3.35	Alpha-catenin/vinculin-like	gene3d domains	1.20.120.230	12	1	14470	43	CTNNA2
3.510e-02	-3.35	SYT6 (synaptotagmin 6)	protein interactions	148281	117	2	19454	49	AHCYL2,NRXN1
3.510e-02	-3.35	ELK3 (ETS transcription factor ELK3)	protein interactions	2004	117	2	19454	49	NFIA,TRPS1
3.514e-02	-3.35	cerebellar Purkinje cell differentiation	biological process	GO:0021702	13	1	18204	50	RORA
3.514e-02	-3.35	postsynaptic specialization assembly	biological process	GO:0098698	13	1	18204	50	NRXN1
3.514e-02	-3.35	regulation of respiratory gaseous exchange by nervous system process	biological process	GO:0002087	13	1	18204	50	ATP1A2
3.514e-02	-3.35	T-helper 17 cell differentiation	biological process	GO:0072539	13	1	18204	50	RORA
3.514e-02	-3.35	olfactory bulb interneuron differentiation	biological process	GO:0021889	13	1	18204	50	ERBB4
3.514e-02	-3.35	glial cell fate commitment	biological process	GO:0021781	13	1	18204	50	NFIA
3.514e-02	-3.35	negative regulation of cytosolic calcium ion concentration	biological process	GO:0051481	13	1	18204	50	ATP1A2
3.514e-02	-3.35	prepulse inhibition	biological process	GO:0060134	13	1	18204	50	CTNNA2
3.545e-02	-3.34	NEDD4 (NEDD4 E3 ubiquitin protein ligase)	protein interactions	4734	494	4	19454	49	TNIK,FGFR3,MAML2,ERBB4
3.553e-02	-3.34	lung-carcinoma-adenocarcinoma	COSMIC cancer mutations	lung-carcinoma-adenocarcinoma	15133	48	16828	49	RORA,PTGDS,ABLIM1,NKAIN3,COL5A3,GPC5,SFXN5,TRPS1,SOX5,MSI2,RFX4,ATP13A4,FGFR3,NCKAP5,ACSS1,ERBB4,NPAS3,SLC1A2,CTNND2,QKI,AHCYL2,NRXN1,PARD3B,PREX2,MAML2,GPM6A,PCDH9,MACF1,ITPR2,LSAMP,NFIA,PTPRZ1,PITPNC1,ZNF98,CDH20,TNIK,FBXL7,HIF3A,ZBTB20,DTNA,ATP1A2,SLC1A3,LRIG1,NTM,CADM1,RYR3,NHSL1,SLC4A4
3.565e-02	-3.33	PLCD3 (phospholipase C delta 3)	protein interactions	113026	118	2	19454	49	TNIK,AHCYL2
3.567e-02	-3.33	OCLN (occludin)	protein interactions	100506658	495	4	19454	49	ABLIM1,MACF1,DTNA,TNIK
3.574e-02	-3.33	human chr6q24.1	chromosome location	human chr6q24.1	19	1	26134	50	NHSL1
3.574e-02	-3.33	human chr11q25	chromosome location	human chr11q25	19	1	26134	50	NTM
3.574e-02	-3.33	human chr5p15.2	chromosome location	human chr5p15.2	19	1	26134	50	CTNND2
3.577e-02	-3.33	microtubule minus-end binding	molecular function	GO:0051011	14	1	18094	47	MACF1
3.581e-02	-3.33	central_nervous_system-brain-glioma-oligodendroglioma_Grade_III	COSMIC cancer mutations	central_nervous_system-brain-glioma-oligodendroglioma_Grade_III	249	3	16828	49	MACF1,FGFR3,PTPRZ1
3.612e-02	-3.32	long-chain fatty acid metabolic process	biological process	GO:0001676	109	2	18204	50	QKI,PTGDS
3.612e-02	-3.32	postsynapse organization	biological process	GO:0099173	109	2	18204	50	NRXN1,CTNND2
3.617e-02	-3.32	small_intestine	COSMIC cancer mutations	small_intestine	250	3	16828	49	TNIK,MACF1,FGFR3
3.621e-02	-3.32	regulation of nervous system development	biological process	GO:0051960	456	4	18204	50	MACF1,QKI,NRXN1,PTPRZ1
3.646e-02	-3.31	skin-scalp-malignant_melanoma	COSMIC cancer mutations	skin-scalp-malignant_melanoma	634	5	16828	49	ERBB4,PREX2,PTPRZ1,NFIA,NTM
3.676e-02	-3.30	HOXB9 (homeobox B9)	protein interactions	3219	120	2	19454	49	NFIA,AHCYL2
3.678e-02	-3.30	HLH_DNA-bd_sf	interpro domains	IPR036638	112	2	18521	50	NPAS3,HIF3A
3.678e-02	-3.30	bHLH_dom	interpro domains	IPR011598	112	2	18521	50	NPAS3,HIF3A
3.695e-02	-3.30	small molecule biosynthetic process	biological process	GO:0044283	459	4	18204	50	SLC1A3,QKI,ACSS1,PTGDS
3.695e-02	-3.30	synaptic signaling	biological process	GO:0099536	459	4	18204	50	DTNA,SLC1A2,SLC1A3,NRXN1
3.702e-02	-3.30	TyrKc	smart domains	SM00219	80	2	9717	37	ERBB4,FGFR3
3.714e-02	-3.29	FGF9 (fibroblast growth factor 9)	protein interactions	2254	15	1	19454	49	FGFR3
3.714e-02	-3.29	TIAM2 (TIAM Rac1 associated GEF 2)	protein interactions	26230	15	1	19454	49	TNIK
3.714e-02	-3.29	TESPA1 (thymocyte expressed, positive selection associated 1)	protein interactions	9840	15	1	19454	49	ITPR2
3.715e-02	-3.29	regulation of multicellular organismal process	biological process	GO:0051239	3113	14	18204	50	MACF1,SFXN5,NRXN1,ATP1A2,ZBTB20,PTPRZ1,CST3,ERBB4,RORA,CADM1,TRPS1,PTGDS,SOX5,QKI
3.721e-02	-3.29	skin-shoulder-malignant_melanoma-nodular	COSMIC cancer mutations	skin-shoulder-malignant_melanoma-nodular	13	1	16828	49	PREX2
3.721e-02	-3.29	Brenner_tumour	COSMIC cancer mutations	Brenner_tumour	13	1	16828	49	FGFR3
3.721e-02	-3.29	endometrium-ovary-endometriosis	COSMIC cancer mutations	endometrium-ovary-endometriosis	13	1	16828	49	FGFR3
3.721e-02	-3.29	central_nervous_system-hypothalamus-glioma-astrocytoma_Grade_I	COSMIC cancer mutations	central_nervous_system-hypothalamus-glioma-astrocytoma_Grade_I	13	1	16828	49	QKI
3.721e-02	-3.29	skin-scalp-malignant_melanoma-nodular	COSMIC cancer mutations	skin-scalp-malignant_melanoma-nodular	13	1	16828	49	PREX2
3.721e-02	-3.29	cervix-carcinoma-adenocarcinoma	COSMIC cancer mutations	cervix-carcinoma-adenocarcinoma	13	1	16828	49	FGFR3
3.721e-02	-3.29	skin-back-carcinoma-basal_cell_carcinoma	COSMIC cancer mutations	skin-back-carcinoma-basal_cell_carcinoma	13	1	16828	49	FGFR3
3.728e-02	-3.29	LIPOCALIN	prosite domains	PS00213	11	1	12186	42	PTGDS
3.728e-02	-3.29	NC1_FIB	prosite domains	PS51461	11	1	12186	42	COL5A3
3.728e-02	-3.29	GATA_ZN_FINGER_2	prosite domains	PS50114	11	1	12186	42	TRPS1
3.728e-02	-3.29	Phospholipase C-mediated cascade; FGFR3	REACTOME pathways	R-HSA-5654227	13	1	10285	30	FGFR3
3.728e-02	-3.29	CLEC7A (Dectin-1) induces NFAT activation	REACTOME pathways	R-HSA-5607763	13	1	10285	30	ITPR2
3.728e-02	-3.29	NOTCH2 intracellular domain regulates transcription	REACTOME pathways	R-HSA-2197563	13	1	10285	30	MAML2
3.728e-02	-3.29	ERBB2 Activates PTK6 Signaling	REACTOME pathways	R-HSA-8847993	13	1	10285	30	ERBB4
3.728e-02	-3.29	Notch-HLH transcription pathway	REACTOME pathways	R-HSA-350054	13	1	10285	30	MAML2
3.728e-02	-3.29	FGFR3c ligand binding and activation	REACTOME pathways	R-HSA-190372	13	1	10285	30	FGFR3
3.728e-02	-3.29	FGFR3 ligand binding and activation	REACTOME pathways	R-HSA-190239	13	1	10285	30	FGFR3
3.732e-02	-3.29	MED15 (mediator complex subunit 15)	protein interactions	51586	121	2	19454	49	QKI,NFIA
3.750e-02	-3.28	central_nervous_system-cerebellum-glioma-astrocytoma_Grade_I	COSMIC cancer mutations	central_nervous_system-cerebellum-glioma-astrocytoma_Grade_I	105	2	16828	49	GPC5,QKI
3.764e-02	-3.28	Ion_trans	pfam domains	PF00520	109	2	17795	50	RYR3,ITPR2
3.771e-02	-3.28	protein localization to membrane	biological process	GO:0072657	462	4	18204	50	TNIK,ERBB4,MACF1,NRXN1
3.779e-02	-3.28	neurotransmitter receptor localization to postsynaptic specialization membrane	biological process	GO:0099645	14	1	18204	50	ERBB4
3.779e-02	-3.28	protein localization to postsynaptic specialization membrane	biological process	GO:0099633	14	1	18204	50	ERBB4
3.779e-02	-3.28	acetyl-CoA biosynthetic process	biological process	GO:0006085	14	1	18204	50	ACSS1
3.779e-02	-3.28	relaxation of cardiac muscle	biological process	GO:0055119	14	1	18204	50	ATP1A2
3.779e-02	-3.28	glutathione biosynthetic process	biological process	GO:0006750	14	1	18204	50	SLC1A2
3.779e-02	-3.28	cellular response to purine-containing compound	biological process	GO:0071415	14	1	18204	50	RYR3
3.779e-02	-3.28	negative regulation of sodium ion transmembrane transporter activity	biological process	GO:2000650	14	1	18204	50	ATP1A2
3.779e-02	-3.28	cellular response to ethanol	biological process	GO:0071361	14	1	18204	50	ITPR2
3.780e-02	-3.28	axolemma	cellular component	GO:0030673	15	1	19108	49	SLC1A2
3.788e-02	-3.27	BRK1 (BRICK1 subunit of SCAR/WAVE actin nucleating complex)	protein interactions	55845	122	2	19454	49	NHSL1,DTNA
3.794e-02	-3.27	regulation of gliogenesis	biological process	GO:0014013	112	2	18204	50	PTPRZ1,QKI
3.798e-02	-3.27	Cadherin-like_dom	interpro domains	IPR002126	114	2	18521	50	CDH20,PCDH9
3.828e-02	-3.26	AMP binding	molecular function	GO:0016208	15	1	18094	47	ACSS1
3.828e-02	-3.26	phosphatidylglycerol binding	molecular function	GO:1901611	15	1	18094	47	PITPNC1
3.844e-02	-3.26	SPSB4 (splA/ryanodine receptor domain and SOCS box containing 4)	protein interactions	92369	123	2	19454	49	PCDH9,LRIG1
3.844e-02	-3.26	PAX7 (paired box 7)	protein interactions	5081	123	2	19454	49	NFIA,TRPS1
3.848e-02	-3.26	VEGFR2 mediated cell proliferation	REACTOME pathways	R-HSA-5218921	258	3	10285	30	ERBB4,FGFR3,ITPR2
3.864e-02	-3.25	GATA	pfam domains	PF00320	14	1	17795	50	TRPS1
3.881e-02	-3.25	bone-humerus-Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour	COSMIC cancer mutations	bone-humerus-Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour	107	2	16828	49	PARD3B,HIF3A
3.900e-02	-3.24	germ_cell_tumour	COSMIC cancer mutations	germ_cell_tumour	867	6	16828	49	TRPS1,TNIK,PREX2,ERBB4,MACF1,FGFR3
3.904e-02	-3.24	secondary active transmembrane transporter activity	molecular function	GO:0015291	289	3	18094	47	SLC1A2,SLC4A4,SLC1A3
3.914e-02	-3.24	skin-leg-malignant_melanoma-nodular	COSMIC cancer mutations	skin-leg-malignant_melanoma-nodular	258	3	16828	49	PTPRZ1,SLC4A4,ATP13A4
3.918e-02	-3.24	regulation of circadian rhythm	biological process	GO:0042752	114	2	18204	50	PTGDS,RORA
3.920e-02	-3.24	Cadherin-like_sf	interpro domains	IPR015919	116	2	18521	50	CDH20,PCDH9
3.943e-02	-3.23	human chr13q31.3	chromosome location	human chr13q31.3	21	1	26134	50	GPC5
3.947e-02	-3.23	testis-germ_cell_tumour-seminoma	COSMIC cancer mutations	testis-germ_cell_tumour-seminoma	648	5	16828	49	FGFR3,PREX2,TNIK,ERBB4,TRPS1
3.954e-02	-3.23	Cadherin	pfam domains	PF00028	112	2	17795	50	PCDH9,CDH20
3.956e-02	-3.23	SYTL2 (synaptotagmin like 2)	protein interactions	54843	16	1	19454	49	NRXN1
3.956e-02	-3.23	CDH12 (cadherin 12)	protein interactions	1010	16	1	19454	49	CTNNA2
3.956e-02	-3.23	Sumo3 (small ubiquitin-like modifier 3)	protein interactions	20610	16	1	19454	49	ITPR2
3.956e-02	-3.23	CTSK (cathepsin K)	protein interactions	1513	16	1	19454	49	FGFR3
3.956e-02	-3.23	SYT4 (synaptotagmin 4)	protein interactions	6860	16	1	19454	49	NRXN1
3.956e-02	-3.23	NBL1 (NBL1, DAN family BMP antagonist)	protein interactions	4681	16	1	19454	49	LRIG1
3.956e-02	-3.23	SAPCD1 (suppressor APC domain containing 1)	protein interactions	401251	16	1	19454	49	CTNNA2
3.956e-02	-3.23	SYT9 (synaptotagmin 9)	protein interactions	143425	16	1	19454	49	NRXN1
3.956e-02	-3.23	CNTNAP2 (contactin associated protein 2)	protein interactions	26047	16	1	19454	49	MACF1
3.956e-02	-3.23	TWIST2 (twist family bHLH transcription factor 2)	protein interactions	117581	16	1	19454	49	ZBTB20
3.956e-02	-3.23	TMEM134 (transmembrane protein 134)	protein interactions	80194	16	1	19454	49	ERBB4
3.956e-02	-3.23	AMMECR1L (AMMECR1 like)	protein interactions	83607	16	1	19454	49	MACF1
3.956e-02	-3.23	HLA-H (major histocompatibility complex, class I, H (pseudogene))	protein interactions	3136	16	1	19454	49	FGFR3
3.956e-02	-3.23	GALNT13 (polypeptide N-acetylgalactosaminyltransferase 13)	protein interactions	114805	16	1	19454	49	TNIK
3.967e-02	-3.23	skin-head_neck-carcinoma-squamous_cell_carcinoma	COSMIC cancer mutations	skin-head_neck-carcinoma-squamous_cell_carcinoma	14191	46	16828	49	DTNA,ATP1A2,SLC1A3,ZBTB20,NTM,LRIG1,SLC4A4,NHSL1,RYR3,CADM1,GPM6A,ITPR2,LSAMP,PCDH9,MACF1,TNIK,HIF3A,FBXL7,ZNF98,PITPNC1,PTPRZ1,NFIA,CDH20,ACSS1,RFX4,NCKAP5,FGFR3,ATP13A4,PREX2,MAML2,QKI,AHCYL2,CTNND2,SLC1A2,NPAS3,ERBB4,NRXN1,PARD3B,COL5A3,NKAIN3,SFXN5,GPC5,RORA,ABLIM1,SOX5,TRPS1
3.971e-02	-3.23	gliogenesis	biological process	GO:0042063	275	3	18204	50	PTPRZ1,QKI,NFIA
3.975e-02	-3.23	ATPase_P-typ_cation-transptr_C	interpro domains	IPR006068	15	1	18521	50	ATP1A2
3.975e-02	-3.23	CNH_dom	interpro domains	IPR001180	15	1	18521	50	TNIK
3.975e-02	-3.23	Znf_GATA	interpro domains	IPR000679	15	1	18521	50	TRPS1
4.002e-02	-3.22	soft_tissue-small_round_cell_tumour	COSMIC cancer mutations	soft_tissue-small_round_cell_tumour	14	1	16828	49	FGFR3
4.002e-02	-3.22	in_situ_neoplasm	COSMIC cancer mutations	in_situ_neoplasm	14	1	16828	49	FGFR3
4.002e-02	-3.22	small_round_cell_tumour	COSMIC cancer mutations	small_round_cell_tumour	14	1	16828	49	FGFR3
4.002e-02	-3.22	urinary_tract-renal_pelvis-carcinoma-transitional_cell_carcinoma	COSMIC cancer mutations	urinary_tract-renal_pelvis-carcinoma-transitional_cell_carcinoma	14	1	16828	49	FGFR3
4.002e-02	-3.22	endometriosis	COSMIC cancer mutations	endometriosis	14	1	16828	49	FGFR3
4.008e-02	-3.22	learning or memory	biological process	GO:0007611	276	3	18204	50	NRXN1,PTPRZ1,ATP1A2
4.010e-02	-3.22	DCC mediated attractive signaling	REACTOME pathways	R-HSA-418885	14	1	10285	30	ABLIM1
4.010e-02	-3.22	SHC1 events in ERBB4 signaling	REACTOME pathways	R-HSA-1250347	14	1	10285	30	ERBB4
4.016e-02	-3.21	SYP (synaptophysin)	protein interactions	6855	126	2	19454	49	PITPNC1,GPM6A
4.027e-02	-3.21	postsynaptic density, intracellular component	cellular component	GO:0099092	16	1	19108	49	TNIK
4.043e-02	-3.21	cerebellar Purkinje cell layer formation	biological process	GO:0021694	15	1	18204	50	RORA
4.043e-02	-3.21	regulation of circadian sleep/wake cycle, sleep	biological process	GO:0045187	15	1	18204	50	PTGDS
4.043e-02	-3.21	synapse maturation	biological process	GO:0060074	15	1	18204	50	NFIA
4.043e-02	-3.21	neuroblast division	biological process	GO:0055057	15	1	18204	50	SOX5
4.043e-02	-3.21	response to caffeine	biological process	GO:0031000	15	1	18204	50	RYR3
4.043e-02	-3.21	sarcoplasmic reticulum calcium ion transport	biological process	GO:0070296	15	1	18204	50	RYR3
4.043e-02	-3.21	intracellular potassium ion homeostasis	biological process	GO:0030007	15	1	18204	50	ATP1A2
4.043e-02	-3.21	chondrocyte proliferation	biological process	GO:0035988	15	1	18204	50	FGFR3
4.043e-02	-3.21	exit from mitosis	biological process	GO:0010458	15	1	18204	50	NFIA
4.043e-02	-3.21	regulation of neuron projection arborization	biological process	GO:0150011	15	1	18204	50	MACF1
4.043e-02	-3.21	protein homotrimerization	biological process	GO:0070207	15	1	18204	50	SLC1A2
4.043e-02	-3.21	negative regulation of sodium ion transmembrane transport	biological process	GO:1902306	15	1	18204	50	ATP1A2
4.078e-02	-3.20	oxysterol binding	molecular function	GO:0008142	16	1	18094	47	RORA
4.081e-02	-3.20	Circadian rythm related genes	WikiPathways	WP3594	207	3	5310	20	PTGDS,CST3,RORA
4.083e-02	-3.20	alveolar	COSMIC cancer mutations	alveolar	2414	12	16828	49	NHSL1,RYR3,PREX2,CDH20,PARD3B,NFIA,TRPS1,NPAS3,SLC1A3,MACF1,NCKAP5,FGFR3
4.083e-02	-3.20	soft_tissue-striated_muscle-rhabdomyosarcoma-alveolar	COSMIC cancer mutations	soft_tissue-striated_muscle-rhabdomyosarcoma-alveolar	2414	12	16828	49	SLC1A3,MACF1,NCKAP5,FGFR3,NHSL1,RYR3,PREX2,PARD3B,CDH20,NPAS3,TRPS1,NFIA
4.103e-02	-3.19	CDH1 (cadherin 1)	protein interactions	999	757	5	19454	49	NHSL1,CTNNA2,MACF1,ABLIM1,CTNND2
4.112e-02	-3.19	COLFI	smart domains	SM00038	11	1	9717	37	COL5A3
4.132e-02	-3.19	SYT2 (synaptotagmin 2)	protein interactions	127833	128	2	19454	49	NRXN1,AHCYL2
4.132e-02	-3.19	TEAD2 (TEA domain transcription factor 2)	protein interactions	8463	128	2	19454	49	TRPS1,ZBTB20
4.132e-02	-3.19	MYB (MYB proto-oncogene, transcription factor)	protein interactions	4602	128	2	19454	49	TRPS1,NFIA
4.134e-02	-3.19	CNH	pfam domains	PF00780	15	1	17795	50	TNIK
4.134e-02	-3.19	Cation_ATPase_C	pfam domains	PF00689	15	1	17795	50	ATP1A2
4.152e-02	-3.18	PROTEIN_KINASE_TYR	prosite domains	PS00109	94	2	12186	42	ERBB4,FGFR3
4.168e-02	-3.18	positive regulation of phosphorus metabolic process	biological process	GO:0010562	697	5	18204	50	ERBB4,SLC4A4,FGFR3,TNIK,ZBTB20
4.168e-02	-3.18	positive regulation of phosphate metabolic process	biological process	GO:0045937	697	5	18204	50	FGFR3,TNIK,ZBTB20,ERBB4,SLC4A4
4.190e-02	-3.17	CHD7 (chromodomain helicase DNA binding protein 7)	protein interactions	55636	129	2	19454	49	SOX5,ZBTB20
4.198e-02	-3.17	TAGAP (T cell activation RhoGTPase activating protein)	protein interactions	117289	17	1	19454	49	DTNA
4.198e-02	-3.17	Pef1 (penta-EF hand domain containing 1)	protein interactions	67898	17	1	19454	49	QKI
4.198e-02	-3.17	Shcbp1 (Shc SH2-domain binding protein 1)	protein interactions	20419	17	1	19454	49	GPC5
4.198e-02	-3.17	NOTCH4 (notch receptor 4)	protein interactions	4855	17	1	19454	49	MAML2
4.198e-02	-3.17	PAX4 (paired box 4)	protein interactions	5078	17	1	19454	49	NTM
4.198e-02	-3.17	SEPSECS (Sep (O-phosphoserine) tRNA:Sec (selenocysteine) tRNA synthase)	protein interactions	51091	17	1	19454	49	ABLIM1
4.198e-02	-3.17	MSANTD2 (Myb/SANT DNA binding domain containing 2)	protein interactions	79684	17	1	19454	49	SOX5
4.198e-02	-3.17	DPP6 (dipeptidyl peptidase like 6)	protein interactions	1804	17	1	19454	49	GPM6A
4.198e-02	-3.17	SHD (Src homology 2 domain containing transforming protein D)	protein interactions	56961	17	1	19454	49	ERBB4
4.223e-02	-3.16	large_intestine-adenoma	COSMIC cancer mutations	large_intestine-adenoma	266	3	16828	49	SOX5,RYR3,CDH20
4.265e-02	-3.15	Wnt signaling pathway	biological process	GO:0016055	283	3	18204	50	CTNND2,MACF1,TNIK
4.274e-02	-3.15	adenoid_cystic_carcinoma	COSMIC cancer mutations	adenoid_cystic_carcinoma	1123	7	16828	49	TNIK,RYR3,MAML2,RORA,ERBB4,CTNND2,FGFR3
4.277e-02	-3.15	AFDN (afadin, adherens junction formation factor)	protein interactions	4301	309	3	19454	49	DTNA,MACF1,NRXN1
4.282e-02	-3.15	hypothalamus	COSMIC cancer mutations	hypothalamus	15	1	16828	49	QKI
4.282e-02	-3.15	ureter	COSMIC cancer mutations	ureter	15	1	16828	49	FGFR3
4.290e-02	-3.15	ERBB2 Regulates Cell Motility	REACTOME pathways	R-HSA-6785631	15	1	10285	30	ERBB4
4.290e-02	-3.15	Synthesis of Prostaglandins (PG) and Thromboxanes (TX)	REACTOME pathways	R-HSA-2162123	15	1	10285	30	PTGDS
4.294e-02	-3.15	Helix-loop-helix DNA-binding domain	gene3d domains	4.10.280.10	111	2	14470	43	NPAS3,HIF3A
4.307e-02	-3.14	regulation of respiratory system process	biological process	GO:0044065	16	1	18204	50	ATP1A2
4.307e-02	-3.14	locomotory exploration behavior	biological process	GO:0035641	16	1	18204	50	ATP1A2
4.307e-02	-3.14	S-adenosylmethionine metabolic process	biological process	GO:0046500	16	1	18204	50	AHCYL2
4.307e-02	-3.14	neuron cell-cell adhesion	biological process	GO:0007158	16	1	18204	50	NRXN1
4.307e-02	-3.14	short-chain fatty acid metabolic process	biological process	GO:0046459	16	1	18204	50	ACSS1
4.307e-02	-3.14	asymmetric cell division	biological process	GO:0008356	16	1	18204	50	SOX5
4.307e-02	-3.14	regulation of amino acid import across plasma membrane	biological process	GO:0010958	16	1	18204	50	ATP1A2
4.307e-02	-3.14	regulation of amino acid transmembrane transport	biological process	GO:1903789	16	1	18204	50	ATP1A2
4.307e-02	-3.14	non-proteinogenic amino acid biosynthetic process	biological process	GO:0170043	16	1	18204	50	SLC1A3
4.307e-02	-3.14	nonribosomal peptide biosynthetic process	biological process	GO:0019184	16	1	18204	50	SLC1A2
4.308e-02	-3.14	TRPS1 (transcriptional repressor GATA binding 1)	protein interactions	7227	131	2	19454	49	NFIA,SOX5
4.308e-02	-3.14	NCOA2 (nuclear receptor coactivator 2)	protein interactions	10499	131	2	19454	49	RORA,NFIA
4.308e-02	-3.14	ZNF609 (zinc finger protein 609)	protein interactions	23060	131	2	19454	49	NFIA,SOX5
4.311e-02	-3.14	human chr2q34	chromosome location	human chr2q34	23	1	26134	50	ERBB4
4.327e-02	-3.14	transmembrane receptor protein tyrosine phosphatase activity	molecular function	GO:0005001	17	1	18094	47	PTPRZ1
4.327e-02	-3.14	transmembrane receptor protein phosphatase activity	molecular function	GO:0019198	17	1	18094	47	PTPRZ1
4.352e-02	-3.13	skin-chest-malignant_melanoma	COSMIC cancer mutations	skin-chest-malignant_melanoma	114	2	16828	49	PREX2,ERBB4
4.379e-02	-3.13	export from cell	biological process	GO:0140352	485	4	18204	50	SLC4A4,NRXN1,ATP1A2,PTGDS
4.381e-02	-3.13	TYRKINASE	prints domains	PR00109	98	2	5227	18	ERBB4,FGFR3
4.410e-02	-3.12	prostate-adenoma	COSMIC cancer mutations	prostate-adenoma	1634	9	16828	49	MACF1,NPAS3,PTPRZ1,ERBB4,GPC5,HIF3A,SOX5,ZBTB20,COL5A3
4.432e-02	-3.12	MFAP5-mediated ovarian cancer cell motility and invasiveness	WikiPathways	WP3301	12	1	5310	20	RYR3
4.440e-02	-3.11	Cnot2 (CCR4-NOT transcription complex, subunit 2)	protein interactions	72068	18	1	19454	49	MACF1
4.440e-02	-3.11	PTGFR (prostaglandin F receptor)	protein interactions	5737	18	1	19454	49	PTGDS
4.440e-02	-3.11	OPCML (opioid binding protein/cell adhesion molecule like)	protein interactions	4978	18	1	19454	49	NTM
4.440e-02	-3.11	TTC29 (tetratricopeptide repeat domain 29)	protein interactions	83894	18	1	19454	49	MACF1
4.440e-02	-3.11	NECTIN1 (nectin cell adhesion molecule 1)	protein interactions	5818	18	1	19454	49	FGFR3
4.477e-02	-3.11	DWA	smart domains	SM00523	12	1	9717	37	NFIA
4.477e-02	-3.11	ZnF_GATA	smart domains	SM00401	12	1	9717	37	TRPS1
4.487e-02	-3.10	NUFIP1 (nuclear FMR1 interacting protein 1)	protein interactions	26747	134	2	19454	49	NTM,GPM6A
4.493e-02	-3.10	CA_dom	interpro domains	IPR001148	17	1	18521	50	PTPRZ1
4.493e-02	-3.10	PAC	interpro domains	IPR001610	17	1	18521	50	HIF3A
4.493e-02	-3.10	Cystatin_dom	interpro domains	IPR000010	17	1	18521	50	CST3
4.493e-02	-3.10	CA_dom_sf	interpro domains	IPR036398	17	1	18521	50	PTPRZ1
4.493e-02	-3.10	AMP-bd_C	interpro domains	IPR025110	17	1	18521	50	ACSS1
4.506e-02	-3.10	Cadherins	gene3d domains	2.60.40.60	114	2	14470	43	PCDH9,CDH20
4.507e-02	-3.10	ductal_carcinoma	COSMIC cancer mutations	ductal_carcinoma	15798	49	16828	49	SFXN5,GPC5,COL5A3,NKAIN3,ABLIM1,PTGDS,RORA,SOX5,TRPS1,ACSS1,NCKAP5,ATP13A4,FGFR3,RFX4,CST3,MSI2,MAML2,PREX2,PARD3B,NRXN1,SLC1A2,QKI,AHCYL2,CTNND2,NPAS3,ERBB4,PCDH9,MACF1,ITPR2,LSAMP,GPM6A,HIF3A,FBXL7,TNIK,CDH20,PITPNC1,ZNF98,NFIA,PTPRZ1,NTM,LRIG1,ATP1A2,SLC1A3,DTNA,ZBTB20,SLC4A4,NHSL1,RYR3,CADM1
4.547e-02	-3.09	SOX15 (SRY-box transcription factor 15)	protein interactions	6665	135	2	19454	49	TRPS1,NFIA
4.547e-02	-3.09	FOXP1 (forkhead box P1)	protein interactions	27086	135	2	19454	49	NFIA,SOX5
4.557e-02	-3.09	salivary_gland	COSMIC cancer mutations	salivary_gland	1139	7	16828	49	TNIK,RYR3,MAML2,CTNND2,ERBB4,RORA,FGFR3
4.561e-02	-3.09	renal_pelvis	COSMIC cancer mutations	renal_pelvis	16	1	16828	49	FGFR3
4.561e-02	-3.09	normal	COSMIC cancer mutations	normal	16	1	16828	49	FGFR3
4.561e-02	-3.09	urinary_tract-carcinoma	COSMIC cancer mutations	urinary_tract-carcinoma	16	1	16828	49	FGFR3
4.561e-02	-3.09	flank	COSMIC cancer mutations	flank	16	1	16828	49	FGFR3
4.570e-02	-3.09	PI3K events in ERBB2 signaling	REACTOME pathways	R-HSA-1963642	16	1	10285	30	ERBB4
4.570e-02	-3.09	GRB2 events in ERBB2 signaling	REACTOME pathways	R-HSA-1963640	16	1	10285	30	ERBB4
4.570e-02	-3.09	mammary gland epithelial cell differentiation	biological process	GO:0060644	17	1	18204	50	ERBB4
4.570e-02	-3.09	ureter development	biological process	GO:0072189	17	1	18204	50	NFIA
4.570e-02	-3.09	protein trimerization	biological process	GO:0070206	17	1	18204	50	SLC1A2
4.570e-02	-3.09	T-helper 17 type immune response	biological process	GO:0072538	17	1	18204	50	RORA
4.570e-02	-3.09	cell communication by electrical coupling involved in cardiac conduction	biological process	GO:0086064	17	1	18204	50	ATP1A2
4.570e-02	-3.09	T cell mediated cytotoxicity	biological process	GO:0001913	17	1	18204	50	CADM1
4.570e-02	-3.09	cGMP metabolic process	biological process	GO:0046068	17	1	18204	50	RORA
4.570e-02	-3.09	membrane depolarization during cardiac muscle cell action potential	biological process	GO:0086012	17	1	18204	50	ATP1A2
4.570e-02	-3.09	cellular response to ATP	biological process	GO:0071318	17	1	18204	50	RYR3
4.570e-02	-3.09	viral genome replication	biological process	GO:0019079	17	1	18204	50	NFIA
4.570e-02	-3.09	cell migration in hindbrain	biological process	GO:0021535	17	1	18204	50	CTNNA2
4.570e-02	-3.09	microvillus assembly	biological process	GO:0030033	17	1	18204	50	TNIK
4.576e-02	-3.08	phosphatidylcholine transporter activity	molecular function	GO:0008525	18	1	18094	47	PITPNC1
4.576e-02	-3.08	GABA receptor binding	molecular function	GO:0050811	18	1	18094	47	ERBB4
4.613e-02	-3.08	PDZ	pfam domains	PF00595	122	2	17795	50	PARD3B,PREX2
4.629e-02	-3.07	Hypoxic and oxygen homeostasis regulation of HIF-1-alpha	Pathway Interaction DB	hif1apathway	15	1	2226	7	HIF3A
4.631e-02	-3.07	cellular response to growth factor stimulus	biological process	GO:0071363	494	4	18204	50	FGFR3,NFIA,SOX5,ERBB4
4.669e-02	-3.06	TBL1X (transducin beta like 1 X-linked)	protein interactions	6907	137	2	19454	49	SOX5,NFIA
4.671e-02	-3.06	EF-hand	gene3d domains	1.10.238.10	272	3	14470	43	MACF1,RYR3,DTNA
4.673e-02	-3.06	ZZ	pfam domains	PF00569	17	1	17795	50	DTNA
4.673e-02	-3.06	Carb_anhydrase	pfam domains	PF00194	17	1	17795	50	PTPRZ1
4.673e-02	-3.06	AMP-binding_C	pfam domains	PF13193	17	1	17795	50	ACSS1
4.673e-02	-3.06	Cystatin	pfam domains	PF00031	17	1	17795	50	CST3
4.681e-02	-3.06	INKA1 (inka box actin regulator 1)	protein interactions	389119	19	1	19454	49	ZBTB20
4.681e-02	-3.06	C3orf62 (chromosome 3 open reading frame 62)	protein interactions	375341	19	1	19454	49	ATP1A2
4.681e-02	-3.06	NLGN1 (neuroligin 1)	protein interactions	22871	19	1	19454	49	NRXN1
4.681e-02	-3.06	PHYHIPL (phytanoyl-CoA 2-hydroxylase interacting protein like)	protein interactions	84457	19	1	19454	49	GPM6A
4.681e-02	-3.06	HBEGF (heparin binding EGF like growth factor)	protein interactions	1839	19	1	19454	49	ERBB4
4.681e-02	-3.06	CNTNAP4 (contactin associated protein family member 4)	protein interactions	85445	19	1	19454	49	MACF1
4.681e-02	-3.06	TNR (tenascin R)	protein interactions	7143	19	1	19454	49	PTPRZ1
4.681e-02	-3.06	ZNF532 (zinc finger protein 532)	protein interactions	55205	19	1	19454	49	ERBB4
4.681e-02	-3.06	RIT2 (Ras like without CAAX 2)	protein interactions	6014	19	1	19454	49	DTNA
4.681e-02	-3.06	SPZ1 (spermatogenic leucine zipper 1)	protein interactions	84654	19	1	19454	49	DTNA
4.681e-02	-3.06	SYT7 (synaptotagmin 7)	protein interactions	9066	19	1	19454	49	NRXN1
4.722e-02	-3.05	central_nervous_system-brain-glioma-astrocytoma_Grade_IV	COSMIC cancer mutations	central_nervous_system-brain-glioma-astrocytoma_Grade_IV	15813	49	16828	49	TRPS1,SOX5,ABLIM1,PTGDS,RORA,SFXN5,GPC5,COL5A3,NKAIN3,NRXN1,PARD3B,SLC1A2,QKI,CTNND2,AHCYL2,ERBB4,NPAS3,MAML2,PREX2,NCKAP5,ATP13A4,FGFR3,RFX4,CST3,MSI2,ACSS1,CDH20,PITPNC1,ZNF98,NFIA,PTPRZ1,HIF3A,FBXL7,TNIK,PCDH9,MACF1,LSAMP,ITPR2,GPM6A,CADM1,SLC4A4,NHSL1,RYR3,NTM,LRIG1,DTNA,SLC1A3,ATP1A2,ZBTB20
4.734e-02	-3.05	NAD+ Signalling and Aging	SMPDB pathways	SMP0084271	11	1	1369	6	RORA
4.752e-02	-3.05	Furin_repeat	interpro domains	IPR006212	18	1	18521	50	ERBB4
4.752e-02	-3.05	Leu-rich_rpt_4	interpro domains	IPR025875	18	1	18521	50	LRIG1
4.752e-02	-3.05	Leu-rich_rpt_Cys-con_subtyp	interpro domains	IPR006553	18	1	18521	50	FBXL7
4.764e-02	-3.04	cation-transporting ATPase complex	cellular component	GO:0090533	19	1	19108	49	ATP1A2
4.764e-02	-3.04	astrocyte projection	cellular component	GO:0097449	19	1	19108	49	SLC1A2
4.764e-02	-3.04	parallel fiber to Purkinje cell synapse	cellular component	GO:0098688	19	1	19108	49	GPM6A
4.764e-02	-3.04	postsynaptic specialization, intracellular component	cellular component	GO:0099091	19	1	19108	49	TNIK
4.792e-02	-3.04	DUSP22 (dual specificity phosphatase 22)	protein interactions	56940	139	2	19454	49	QKI,CTNNA2
4.793e-02	-3.04	Cell-type Dependent Selectivity of CCK2R Signaling	WikiPathways	WP3679	13	1	5310	20	RYR3
4.802e-02	-3.04	ligand-gated monoatomic cation channel activity	molecular function	GO:0099094	135	2	18094	47	ITPR2,RYR3
4.804e-02	-3.04	carboxylic acid transport	biological process	GO:0046942	297	3	18204	50	SFXN5,SLC1A3,SLC1A2
4.804e-02	-3.04	muscle system process	biological process	GO:0003012	297	3	18204	50	RYR3,ATP1A2,DTNA
4.804e-02	-3.04	skeletal system development	biological process	GO:0001501	500	4	18204	50	NFIA,SOX5,TRPS1,FGFR3
4.822e-02	-3.03	cell population proliferation	biological process	GO:0008283	726	5	18204	50	CADM1,FGFR3,SOX5,NFIA,RORA
4.824e-02	-3.03	alkali metal ion binding	molecular function	GO:0031420	19	1	18094	47	ATP1A2
4.832e-02	-3.03	dendritic spine morphogenesis	biological process	GO:0060997	18	1	18204	50	CTNND2
4.832e-02	-3.03	negative regulation of sodium ion transport	biological process	GO:0010766	18	1	18204	50	ATP1A2
4.832e-02	-3.03	regulation of extracellular matrix disassembly	biological process	GO:0010715	18	1	18204	50	CST3
4.832e-02	-3.03	positive regulation of circadian rhythm	biological process	GO:0042753	18	1	18204	50	RORA
4.839e-02	-3.03	squamous_cell_carcinoma_BRAF_inhibitor_related	COSMIC cancer mutations	squamous_cell_carcinoma_BRAF_inhibitor_related	17	1	16828	49	FGFR3
4.839e-02	-3.03	verrucal_keratosis_BRAF_inhibitor_related	COSMIC cancer mutations	verrucal_keratosis_BRAF_inhibitor_related	17	1	16828	49	FGFR3
4.839e-02	-3.03	skin-non_chronically_sun_exposed_site-malignant_melanoma	COSMIC cancer mutations	skin-non_chronically_sun_exposed_site-malignant_melanoma	17	1	16828	49	FGFR3
4.839e-02	-3.03	optic_nerve	COSMIC cancer mutations	optic_nerve	17	1	16828	49	QKI
4.839e-02	-3.03	skin-other-verrucal_keratosis_BRAF_inhibitor_related	COSMIC cancer mutations	skin-other-verrucal_keratosis_BRAF_inhibitor_related	17	1	16828	49	FGFR3
4.839e-02	-3.03	central_nervous_system-optic_nerve-glioma-astrocytoma_Grade_I	COSMIC cancer mutations	central_nervous_system-optic_nerve-glioma-astrocytoma_Grade_I	17	1	16828	49	QKI
4.839e-02	-3.03	non_chronically_sun_exposed_site	COSMIC cancer mutations	non_chronically_sun_exposed_site	17	1	16828	49	FGFR3
4.839e-02	-3.03	breast-carcinoma-neuroendocrine_carcinoma	COSMIC cancer mutations	breast-carcinoma-neuroendocrine_carcinoma	17	1	16828	49	FGFR3
4.839e-02	-3.03	skin-carcinoma-squamous_cell_carcinoma_BRAF_inhibitor_related	COSMIC cancer mutations	skin-carcinoma-squamous_cell_carcinoma_BRAF_inhibitor_related	17	1	16828	49	FGFR3
4.843e-02	-3.03	organic acid transport	biological process	GO:0015849	298	3	18204	50	SLC1A2,SLC1A3,SFXN5
4.848e-02	-3.03	Elevation of cytosolic Ca2+ levels	REACTOME pathways	R-HSA-139853	17	1	10285	30	ITPR2
4.853e-02	-3.03	SATB2 (SATB homeobox 2)	protein interactions	23314	140	2	19454	49	NFIA,SOX5
4.853e-02	-3.03	WDR48 (WD repeat domain 48)	protein interactions	57599	140	2	19454	49	AHCYL2,FBXL7
4.859e-02	-3.02	human chr18q12.1	chromosome location	human chr18q12.1	26	1	26134	50	DTNA
4.880e-02	-3.02	KLF8 (KLF transcription factor 8)	protein interactions	11279	326	3	19454	49	TRPS1,SOX5,NFIA
4.894e-02	-3.02	response to organophosphorus	biological process	GO:0046683	129	2	18204	50	ITPR2,RYR3
4.916e-02	-3.01	UPK2 (uroplakin 2)	protein interactions	7379	141	2	19454	49	CTNNA2,PCDH9
4.921e-02	-3.01	FAM13C (family with sequence similarity 13 member C)	protein interactions	220965	20	1	19454	49	AHCYL2
4.921e-02	-3.01	ANXA13 (annexin A13)	protein interactions	312	20	1	19454	49	MSI2
4.921e-02	-3.01	MLC1 (modulator of VRAC current 1)	protein interactions	23209	20	1	19454	49	DTNA
4.921e-02	-3.01	CACFD1 (calcium channel flower domain containing 1)	protein interactions	11094	20	1	19454	49	PITPNC1
4.921e-02	-3.01	ADRA1D (adrenoceptor alpha 1D)	protein interactions	146	20	1	19454	49	DTNA
4.921e-02	-3.01	CCKBR (cholecystokinin B receptor)	protein interactions	887	20	1	19454	49	NTM
4.921e-02	-3.01	RNF183 (ring finger protein 183)	protein interactions	138065	20	1	19454	49	PTGDS
4.921e-02	-3.01	PON1 (paraoxonase 1)	protein interactions	5444	20	1	19454	49	SFXN5
4.921e-02	-3.01	Kif1c (kinesin family member 1C)	protein interactions	16562	20	1	19454	49	ABLIM1
4.921e-02	-3.01	Sass6 (SAS-6 centriolar assembly protein)	protein interactions	72776	20	1	19454	49	MACF1
4.921e-02	-3.01	NCAM2 (neural cell adhesion molecule 2)	protein interactions	4685	20	1	19454	49	CTNND2
4.921e-02	-3.01	OXT (oxytocin/neurophysin I prepropeptide)	protein interactions	5020	20	1	19454	49	FGFR3
4.921e-02	-3.01	ALX3 (ALX homeobox 3)	protein interactions	257	20	1	19454	49	MACF1
4.921e-02	-3.01	SNX20 (sorting nexin 20)	protein interactions	124460	20	1	19454	49	AHCYL2
4.936e-02	-3.01	-	gene3d domains	2.60.120.1000	17	1	14470	43	COL5A3
4.936e-02	-3.01	Alpha carbonic anhydrase	gene3d domains	3.10.200.10	17	1	14470	43	PTPRZ1
4.941e-02	-3.01	LRR_4	pfam domains	PF12799	18	1	17795	50	LRIG1
4.951e-02	-3.01	cellular response to organonitrogen compound	biological process	GO:0071417	505	4	18204	50	ITPR2,RYR3,SLC1A3,SLC1A2
4.962e-02	-3.00	thalamus	COSMIC cancer mutations	thalamus	284	3	16828	49	DTNA,QKI,FGFR3
4.991e-02	-3.00	NCOR1 (nuclear receptor corepressor 1)	protein interactions	9611	329	3	19454	49	SOX5,ERBB4,NFIA