Gene Ontology Enrichment Results

Homer de novo Motif Enrichment Results
Known Motif Enrichment Results

Text file version of complete results (i.e. open with Excel)

biological process: Functional groupings of proteins (Gene Ontology)

molecular function: Mechanistic actions of proteins (Gene Ontology)

cellular component: Protein localization (Gene Ontology)

chromosome location: Genes with similar chromosome localization (NCBI Gene)

KEGG pathways: Groups of proteins in the same pathways (KEGG)

protein interactions: "Proteins interacting with a common protein (BIND, EcoCyc, HPRD)" (NCBI Gene)

interpro domains: Proteins with similar domains and features (Interpro)

pfam domains: Proteins with similar domains and features (Pfam)

smart domains: Proteins with similar domains and features (SMART)

gene3d domains: Proteins with similar domains and features (Gene3D)

prosite domains: Proteins with similar domains and features (Prosite)

prints domains: Proteins with similar domains and features (PRINTS)

MSigDB lists: "Genes sets for pathways, factor/miRNA target predictions, expression patterns, etc." (MSigDB)

BIOCYC pathways: Groups of proteins in the same pathways (BIOCYC)

COSMIC cancer mutations: Genes mutated in similar cancers (COSMIC)

GWAS genes: Genes mutated in similar diseases (GWAS Catalog)

Lipid Maps pathways: Groups of proteins in the same lipid pathways (Lipid Maps/Biosystems)

Pathway Interaction DB: Groups of proteins in the same pathways (Pathway Interaction Database)

REACTOME pathways: Groups of proteins in the same pathways (REACTOME)

SMPDB pathways: Groups of proteins in the same pathways (SMPDB)

WikiPathways: Groups of proteins in the same pathways (Wikipathways)

Enriched Categories

P-value	ln(P)	Term	GO Tree	GO ID	# of Genes in Term	# of Target Genes in Term	# of Total Genes	# of Target Genes	Common Genes
9.808e-09	-18.44	PRNP (prion protein (Kanno blood group))	protein interactions	5621	1118	16	19454	50	MAML2,ATP1A2,SLC1A3,APOE,SPARCL1,LSAMP,AHCYL2,PTPRZ1,GPM6A,NHSL1,CLU,CPE,MSI2,TRPS1,QKI,SLC4A4
5.023e-08	-16.81	prostate-carcinoma	COSMIC cancer mutations	prostate-carcinoma	9000	44	16828	49	COL5A3,PON2,SPARCL1,SOX5,FBXL7,MSI2,DTNA,LSAMP,CLU,SLC4A4,AHCYL2,PITPNC1,NHSL1,CDH20,NTM,ATP13A4,FGFR3,HIF3A,TRPS1,HEPACAM,BMPR1B,NKAIN3,PTPRZ1,NPAS3,SLC1A2,QKI,HPSE2,TNIK,RYR3,RORA,NFIA,ZBTB20,GPC5,GPM6A,CPE,APOE,PARD3B,PREX2,SLC1A3,MAML2,ZNRF3,PCDH9,NRXN1,GLIS3
9.898e-08	-16.13	Astrocytic Glutamate-Glutamine Uptake And Metabolism	REACTOME pathways	R-HSA-210455	4	3	10285	31	SLC1A3,SLC1A2,GLUL
9.898e-08	-16.13	Neurotransmitter uptake and Metabolism In Glial Cells	REACTOME pathways	R-HSA-112313	4	3	10285	31	SLC1A2,GLUL,SLC1A3
1.813e-07	-15.52	haematopoietic_and_lymphoid_tissue-haematopoietic_neoplasm	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue-haematopoietic_neoplasm	764	13	16828	49	GPC5,FBXL7,RYR3,HPSE2,MAML2,SOX5,PCDH9,PREX2,SLC1A2,NKAIN3,ATP1A2,LSAMP,COL5A3
2.059e-07	-15.40	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-acute_lymphoblastic_B_cell_leukaemia	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-acute_lymphoblastic_B_cell_leukaemia	3828	28	16828	49	SLC1A3,PREX2,LSAMP,CPE,PAMR1,SLC4A4,HIF3A,NRXN1,GLIS3,MAML2,NTM,PCDH9,ATP13A4,NKAIN3,PTPRZ1,SLC1A2,BMPR1B,COL5A3,FBXL7,NFIA,GPC5,ZBTB20,GPM6A,HPSE2,RYR3,TNIK,SOX5,RORA
2.059e-07	-15.40	acute_lymphoblastic_B_cell_leukaemia	COSMIC cancer mutations	acute_lymphoblastic_B_cell_leukaemia	3828	28	16828	49	PREX2,SLC1A3,SLC4A4,CPE,PAMR1,LSAMP,GLIS3,NRXN1,HIF3A,PCDH9,ATP13A4,MAML2,NTM,SLC1A2,PTPRZ1,NKAIN3,COL5A3,BMPR1B,GPM6A,GPC5,ZBTB20,NFIA,FBXL7,RORA,RYR3,HPSE2,TNIK,SOX5
2.486e-07	-15.21	brainstem	COSMIC cancer mutations	brainstem	3102	25	16828	49	AHCYL2,LSAMP,CPE,SLC1A3,PREX2,CDH20,MAML2,PCDH9,FGFR3,ZNRF3,ATP13A4,PTPRZ1,SLC1A2,NPAS3,NKAIN3,RYR3,HPSE2,TNIK,SOX5,RORA,QKI,GPC5,ZBTB20,GPM6A,FBXL7
2.687e-07	-15.13	cell periphery	cellular component	GO:0071944	6020	33	19108	49	PREX2,CDH20,ZNRF3,NRXN1,DTNA,GPM6A,GPC5,CTNNA2,SLC4A4,NKAIN3,APOE,PCDH9,TNIK,CPE,HIF3A,SPARCL1,FGFR3,RYR3,LSAMP,PARD3B,NTM,PTPRZ1,SLC1A3,ATP1A2,CST3,GLUL,BMPR1B,PON2,COL5A3,SLC1A2,CLU,HPSE2,ATP13A4
3.120e-07	-14.98	nervous system development	biological process	GO:0007399	2185	20	18204	49	SOX5,SLC1A3,NRXN1,LSAMP,APOE,NFIA,CTNNA2,ATP1A2,NTM,TNIK,GPM6A,MSI2,PCDH9,PREX2,RORA,QKI,SLC1A2,PTPRZ1,BMPR1B,CLU
3.509e-07	-14.86	multicellular organism development	biological process	GO:0007275	3957	27	18204	49	SLC1A3,HIF3A,ATP1A2,CTNNA2,LSAMP,NRXN1,BMPR1B,PTPRZ1,QKI,PCDH9,PREX2,CPE,GPM6A,TRPS1,ZNRF3,CDH20,SOX5,APOE,NFIA,FGFR3,RORA,SLC1A2,MSI2,NTM,TNIK,CLU,GLUL
5.795e-07	-14.36	central_nervous_system-brainstem-glioma-astrocytoma_Grade_IV	COSMIC cancer mutations	central_nervous_system-brainstem-glioma-astrocytoma_Grade_IV	2531	22	16828	49	FBXL7,GPC5,ZBTB20,GPM6A,QKI,TNIK,RYR3,HPSE2,SOX5,MAML2,PCDH9,RORA,ATP13A4,ZNRF3,NKAIN3,PTPRZ1,PREX2,SLC1A3,CDH20,LSAMP,CPE,AHCYL2
6.811e-07	-14.20	myelodysplastic_syndrome	COSMIC cancer mutations	myelodysplastic_syndrome	1174	15	16828	49	SLC1A2,NPAS3,PREX2,NKAIN3,ATP1A2,COL5A3,BMPR1B,LSAMP,NFIA,FBXL7,FGFR3,TNIK,HPSE2,RYR3,SOX5
6.811e-07	-14.20	haematopoietic_and_lymphoid_tissue-haematopoietic_neoplasm-myelodysplastic_syndrome	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue-haematopoietic_neoplasm-myelodysplastic_syndrome	1174	15	16828	49	FBXL7,NFIA,SOX5,TNIK,HPSE2,RYR3,FGFR3,NKAIN3,PREX2,NPAS3,SLC1A2,LSAMP,BMPR1B,COL5A3,ATP1A2
6.920e-07	-14.18	system development	biological process	GO:0048731	3533	25	18204	49	PCDH9,CPE,PREX2,GPM6A,TRPS1,BMPR1B,PTPRZ1,QKI,NRXN1,HIF3A,ATP1A2,CTNNA2,LSAMP,SLC1A3,GLUL,CLU,MSI2,NTM,TNIK,RORA,SLC1A2,FGFR3,APOE,NFIA,SOX5
9.787e-07	-13.84	cell junction	cellular component	GO:0030054	2224	19	19108	49	ATP1A2,HEPACAM,TNIK,PCDH9,APOE,FGFR3,SPARCL1,CLU,SLC1A2,QKI,PARD3B,PTPRZ1,CDH20,NFIA,SLC1A3,NRXN1,CTNNA2,GPM6A,DTNA
1.275e-06	-13.57	neurogenesis	biological process	GO:0022008	1334	15	18204	49	SOX5,SLC1A3,NFIA,APOE,CTNNA2,NRXN1,PTPRZ1,QKI,RORA,BMPR1B,TNIK,GPM6A,NTM,PREX2,CLU
1.606e-06	-13.34	cell morphogenesis	biological process	GO:0000902	687	11	18204	49	NRXN1,CTNNA2,NFIA,SLC1A3,CDH20,CLU,PREX2,TNIK,GPM6A,BMPR1B,PTPRZ1
2.063e-06	-13.09	anatomical structure morphogenesis	biological process	GO:0009653	2225	19	18204	49	FGFR3,NRXN1,HIF3A,CTNNA2,APOE,NFIA,SLC1A3,CDH20,SOX5,GLUL,CLU,PREX2,CPE,TNIK,GPM6A,BMPR1B,RORA,PTPRZ1,QKI
2.650e-06	-12.84	plasma membrane	cellular component	GO:0005886	5538	30	19108	49	SLC1A3,PARD3B,NTM,PTPRZ1,GLUL,BMPR1B,PON2,SLC1A2,HPSE2,ATP13A4,ATP1A2,CST3,NRXN1,GPM6A,DTNA,GPC5,CTNNA2,PREX2,CDH20,ZNRF3,FGFR3,RYR3,LSAMP,SLC4A4,NKAIN3,APOE,PCDH9,TNIK,CPE,HIF3A
3.226e-06	-12.64	Burkitt_lymphoma	COSMIC cancer mutations	Burkitt_lymphoma	2119	19	16828	49	GPM6A,GPC5,FBXL7,PCDH9,ATP13A4,RYR3,HPSE2,SOX5,MAML2,SLC1A2,NHSL1,NPAS3,SLC1A3,PREX2,NKAIN3,AHCYL2,CPE,BMPR1B,LSAMP
3.226e-06	-12.64	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-Burkitt_lymphoma	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-Burkitt_lymphoma	2119	19	16828	49	AHCYL2,CPE,BMPR1B,LSAMP,SLC1A2,NHSL1,NPAS3,PREX2,SLC1A3,NKAIN3,PCDH9,ATP13A4,RYR3,HPSE2,SOX5,MAML2,GPM6A,GPC5,FBXL7
4.244e-06	-12.37	upper_aerodigestive_tract-larynx-carcinoma-squamous_cell_carcinoma	COSMIC cancer mutations	upper_aerodigestive_tract-larynx-carcinoma-squamous_cell_carcinoma	1946	18	16828	49	MAML2,SOX5,TNIK,HPSE2,RYR3,RORA,ZNRF3,FGFR3,PCDH9,NRXN1,ZBTB20,GPM6A,BMPR1B,COL5A3,PARD3B,AHCYL2,SLC4A4,NPAS3
4.307e-06	-12.36	larynx	COSMIC cancer mutations	larynx	1948	18	16828	49	PCDH9,FGFR3,ZNRF3,RORA,TNIK,RYR3,HPSE2,SOX5,MAML2,GPM6A,ZBTB20,NRXN1,COL5A3,BMPR1B,AHCYL2,SLC4A4,PARD3B,NPAS3
7.570e-06	-11.79	anatomical structure development	biological process	GO:0048856	5207	29	18204	49	FGFR3,NFIA,APOE,CDH20,SOX5,GLUL,CLU,SPARCL1,MSI2,TNIK,NTM,SLC1A2,RORA,NRXN1,CTNNA2,ATP1A2,HIF3A,LSAMP,SLC1A3,COL5A3,CPE,PREX2,PCDH9,TRPS1,GPM6A,ZNRF3,BMPR1B,PTPRZ1,QKI
7.967e-06	-11.74	generation of neurons	biological process	GO:0048699	1158	13	18204	49	NRXN1,NFIA,APOE,CTNNA2,SOX5,GPM6A,TNIK,NTM,PREX2,SLC1A3,PTPRZ1,RORA,BMPR1B
1.002e-05	-11.51	cerebellum	COSMIC cancer mutations	cerebellum	769	11	16828	49	MAML2,PARD3B,RYR3,HPSE2,PCDH9,CPE,QKI,PTPRZ1,NRXN1,GPC5,NPAS3
1.310e-05	-11.24	central_nervous_system-brain-primitive_neuroectodermal_tumour-medulloblastoma	COSMIC cancer mutations	central_nervous_system-brain-primitive_neuroectodermal_tumour-medulloblastoma	7205	36	16828	49	TRPS1,HEPACAM,GLIS3,NRXN1,ATP13A4,FGFR3,PCDH9,MAML2,NTM,PITPNC1,NHSL1,PREX2,SLC1A3,PAMR1,CPE,LSAMP,SLC4A4,AHCYL2,PARD3B,NFIA,FBXL7,GPM6A,ZBTB20,GPC5,QKI,RORA,SOX5,TNIK,HPSE2,RYR3,NKAIN3,NPAS3,PON2,SLC1A2,PTPRZ1,COL5A3
1.584e-05	-11.05	developmental process	biological process	GO:0032502	5716	30	18204	49	GLUL,CLU,SPARCL1,MSI2,TNIK,NTM,SLC1A2,RORA,FGFR3,NFIA,APOE,SOX5,CDH20,COL5A3,PREX2,CPE,PCDH9,GPM6A,ZNRF3,TRPS1,BMPR1B,QKI,PTPRZ1,NRXN1,ATP1A2,NHSL1,CTNNA2,HIF3A,LSAMP,SLC1A3
1.804e-05	-10.92	diffuse_large_B_cell_lymphoma	COSMIC cancer mutations	diffuse_large_B_cell_lymphoma	4151	26	16828	49	CPE,LSAMP,AHCYL2,ATP1A2,CLU,CDH20,PREX2,SLC1A3,ATP13A4,PCDH9,FGFR3,MAML2,TRPS1,NKAIN3,SLC1A2,SPARCL1,QKI,RORA,SOX5,RYR3,HPSE2,TNIK,FBXL7,GPM6A,DTNA,GPC5
2.153e-05	-10.75	neuron differentiation	biological process	GO:0030182	1081	12	18204	49	PREX2,SLC1A3,GPM6A,TNIK,NTM,BMPR1B,PTPRZ1,RORA,NRXN1,CTNNA2,NFIA,APOE
2.256e-05	-10.70	MAPT (microtubule associated protein tau)	protein interactions	4137	948	11	19454	50	ATP1A2,APOE,SLC1A3,CTNNA2,GPM6A,LSAMP,SLC1A2,HEPACAM,CLU,NTM,TNIK
2.531e-05	-10.58	multicellular organismal process	biological process	GO:0032501	6177	31	18204	49	SLC1A3,ATP1A2,CTNNA2,HIF3A,LSAMP,NRXN1,BMPR1B,PTPRZ1,QKI,PREX2,CPE,PCDH9,GPM6A,TRPS1,ZNRF3,CDH20,SOX5,PTGDS,SLC4A4,NFIA,APOE,RYR3,FGFR3,SLC1A2,RORA,DTNA,MSI2,TNIK,NTM,CLU,GLUL
6.236e-05	-9.68	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-diffuse_large_B_cell_lymphoma	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-diffuse_large_B_cell_lymphoma	3608	23	16828	49	PREX2,CDH20,LSAMP,CPE,CLU,ATP1A2,AHCYL2,MAML2,FGFR3,PCDH9,ATP13A4,NKAIN3,SLC1A2,FBXL7,GPC5,GPM6A,QKI,SPARCL1,TNIK,HPSE2,RYR3,SOX5,RORA
6.571e-05	-9.63	glutamate:sodium symporter activity	molecular function	GO:0015501	5	2	18094	47	SLC1A3,SLC1A2
6.571e-05	-9.63	high-affinity L-glutamate transmembrane transporter activity	molecular function	GO:0005314	5	2	18094	47	SLC1A2,SLC1A3
7.061e-05	-9.56	positive regulation of amyloid fibril formation	biological process	GO:1905908	5	2	18204	49	CLU,APOE
7.061e-05	-9.56	D-aspartate transmembrane transport	biological process	GO:0070777	5	2	18204	49	SLC1A2,SLC1A3
7.061e-05	-9.56	D-aspartate import across plasma membrane	biological process	GO:0070779	5	2	18204	49	SLC1A3,SLC1A2
7.070e-05	-9.56	neurotransmitter uptake	biological process	GO:0001504	30	3	18204	49	SLC1A3,ATP1A2,SLC1A2
7.567e-05	-9.49	acute_myeloid_leukaemia_therapy_related	COSMIC cancer mutations	acute_myeloid_leukaemia_therapy_related	1523	14	16828	49	QKI,RYR3,HPSE2,MAML2,SOX5,PCDH9,RORA,FBXL7,GPC5,LSAMP,COL5A3,NKAIN3,SLC1A3,PREX2
7.567e-05	-9.49	haematopoietic_and_lymphoid_tissue-haematopoietic_neoplasm-acute_myeloid_leukaemia_therapy_related	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue-haematopoietic_neoplasm-acute_myeloid_leukaemia_therapy_related	1523	14	16828	49	SLC1A3,PREX2,NKAIN3,LSAMP,COL5A3,GPC5,FBXL7,HPSE2,RYR3,MAML2,SOX5,PCDH9,RORA,QKI
7.700e-05	-9.47	cell body	cellular component	GO:0044297	556	8	19108	49	ATP1A2,APOE,GLUL,NRXN1,SLC1A3,BMPR1B,GPM6A,SLC1A2
7.981e-05	-9.44	neuron development	biological process	GO:0048666	859	10	18204	49	BMPR1B,PTPRZ1,PREX2,SLC1A3,TNIK,GPM6A,NTM,CTNNA2,APOE,NRXN1
8.255e-05	-9.40	NTM (neurotrimin)	protein interactions	50863	33	3	19454	50	GPM6A,NTM,LSAMP
8.364e-05	-9.39	transport across blood-brain barrier	biological process	GO:0150104	86	4	18204	49	SLC1A3,ATP1A2,SLC4A4,SLC1A2
8.364e-05	-9.39	vascular transport	biological process	GO:0010232	86	4	18204	49	SLC1A3,SLC1A2,SLC4A4,ATP1A2
9.447e-05	-9.27	response to auditory stimulus	biological process	GO:0010996	33	3	18204	49	ATP1A2,SLC1A3,NRXN1
9.646e-05	-9.25	central_nervous_system-cerebellum-primitive_neuroectodermal_tumour-medulloblastoma-SHH_subtype	COSMIC cancer mutations	central_nervous_system-cerebellum-primitive_neuroectodermal_tumour-medulloblastoma-SHH_subtype	653	9	16828	49	CPE,RYR3,HPSE2,PARD3B,MAML2,PCDH9,NRXN1,PTPRZ1,NPAS3
9.759e-05	-9.23	SHH_subtype	COSMIC cancer mutations	SHH_subtype	654	9	16828	49	CPE,PARD3B,MAML2,HPSE2,RYR3,PCDH9,NRXN1,PTPRZ1,NPAS3
9.782e-05	-9.23	blood_vessel	COSMIC cancer mutations	blood_vessel	2211	17	16828	49	LSAMP,COL5A3,NKAIN3,PREX2,SLC1A3,PTPRZ1,SLC1A2,CDH20,SOX5,MAML2,RYR3,HPSE2,PCDH9,FGFR3,FBXL7,GPC5,GPM6A
1.023e-04	-9.19	neuron projection	cellular component	GO:0043005	1331	12	19108	49	AHCYL2,GPM6A,DTNA,CTNNA2,SLC1A3,APOE,PCDH9,HEPACAM,ATP1A2,CLU,SLC1A2,BMPR1B
1.057e-04	-9.15	L-aspartate import across plasma membrane	biological process	GO:0140009	6	2	18204	49	SLC1A3,SLC1A2
1.057e-04	-9.15	D-amino acid transport	biological process	GO:0042940	6	2	18204	49	SLC1A2,SLC1A3
1.104e-04	-9.11	proteoglycan binding	molecular function	GO:0043394	36	3	18094	47	COL5A3,APOE,HPSE2
1.275e-04	-8.97	soft_tissue	COSMIC cancer mutations	soft_tissue	5828	30	16828	49	NHSL1,CDH20,PREX2,SLC1A3,PARD3B,CLU,PAMR1,APOE,LSAMP,GLIS3,TRPS1,ZNRF3,FGFR3,PCDH9,MAML2,NPAS3,SLC1A2,PON2,PTPRZ1,NKAIN3,COL5A3,GPM6A,GPC5,NFIA,FBXL7,RORA,SOX5,HPSE2,RYR3,SPARCL1
1.342e-04	-8.92	mouth	COSMIC cancer mutations	mouth	9004	39	16828	49	RORA,SOX5,RYR3,HPSE2,TNIK,QKI,GPM6A,DTNA,CST3,ZBTB20,GPC5,FBXL7,GLUL,COL5A3,NPAS3,SLC1A2,PTPRZ1,ATP13A4,ZNRF3,PCDH9,FGFR3,NTM,MAML2,NRXN1,HEPACAM,TRPS1,HIF3A,SLC4A4,PARD3B,CLU,ATP1A2,PAMR1,APOE,LSAMP,NHSL1,CDH20,SLC1A3,PREX2,PITPNC1
1.398e-04	-8.88	chondroblastoma	COSMIC cancer mutations	chondroblastoma	534	8	16828	49	LSAMP,PCDH9,AHCYL2,SOX5,RYR3,NKAIN3,GPM6A,GPC5
1.487e-04	-8.81	Na-dicarboxylate_symporter_CS	interpro domains	IPR018107	7	2	18521	50	SLC1A3,SLC1A2
1.487e-04	-8.81	Na-dicarboxylate_symporter	interpro domains	IPR001991	7	2	18521	50	SLC1A3,SLC1A2
1.487e-04	-8.81	Na:dicarbo_symporter_sf	interpro domains	IPR036458	7	2	18521	50	SLC1A2,SLC1A3
1.565e-04	-8.76	cellular response to alkaloid	biological process	GO:0071312	39	3	18204	49	SLC1A2,SLC1A3,RYR3
1.610e-04	-8.73	SDF	pfam domains	PF00375	7	2	17795	50	SLC1A3,SLC1A2
1.707e-04	-8.68	cell adhesion	biological process	GO:0007155	942	10	18204	49	HEPACAM,NRXN1,PARD3B,SPARCL1,CTNNA2,LSAMP,COL5A3,PCDH9,NTM,CDH20
1.879e-04	-8.58	Sodium:dicarboxylate symporter	gene3d domains	1.10.3860.10	7	2	14470	44	SLC1A3,SLC1A2
1.967e-04	-8.53	protein import	biological process	GO:0017038	8	2	18204	49	CLU,APOE
2.049e-04	-8.49	upper_aerodigestive_tract-mouth-carcinoma-squamous_cell_carcinoma	COSMIC cancer mutations	upper_aerodigestive_tract-mouth-carcinoma-squamous_cell_carcinoma	6953	33	16828	49	PAMR1,LSAMP,SLC4A4,PARD3B,ATP1A2,PITPNC1,NHSL1,CDH20,PREX2,ZNRF3,ATP13A4,FGFR3,PCDH9,MAML2,NTM,TRPS1,HEPACAM,HIF3A,NRXN1,GLUL,SLC1A2,PTPRZ1,QKI,RORA,SOX5,TNIK,RYR3,FBXL7,GPM6A,CST3,DTNA,ZBTB20,GPC5
2.216e-04	-8.41	mantle_cell_lymphoma	COSMIC cancer mutations	mantle_cell_lymphoma	2849	19	16828	49	GPM6A,GPC5,TRPS1,HIF3A,FBXL7,PCDH9,ZNRF3,ATP13A4,HPSE2,RYR3,MAML2,SOX5,SLC1A2,SLC1A3,PREX2,NKAIN3,PARD3B,CPE,LSAMP
2.304e-04	-8.38	LSAMP (limbic system associated membrane protein)	protein interactions	4045	9	2	19454	50	NTM,LSAMP
2.304e-04	-8.38	NEGR1 (neuronal growth regulator 1)	protein interactions	257194	9	2	19454	50	LSAMP,NTM
2.409e-04	-8.33	NA_DICARBOXYL_SYMP_1	prosite domains	PS00713	7	2	12186	42	SLC1A2,SLC1A3
2.409e-04	-8.33	NA_DICARBOXYL_SYMP_2	prosite domains	PS00714	7	2	12186	42	SLC1A2,SLC1A3
2.496e-04	-8.30	lymph_node	COSMIC cancer mutations	lymph_node	1703	14	16828	49	TNIK,RYR3,MAML2,SOX5,FGFR3,PCDH9,ATP13A4,GPC5,DTNA,GPM6A,TRPS1,PARD3B,LSAMP,SLC1A3
2.655e-04	-8.23	synapse	cellular component	GO:0045202	1473	12	19108	49	DTNA,GPM6A,SLC1A3,NRXN1,PTPRZ1,QKI,CLU,SLC1A2,SPARCL1,TNIK,APOE,ATP1A2
2.660e-04	-8.23	central nervous system development	biological process	GO:0007417	995	10	18204	49	CTNNA2,ATP1A2,CLU,BMPR1B,SLC1A2,QKI,PTPRZ1,RORA,MSI2,PCDH9
2.806e-04	-8.18	Transport of inorganic cations/anions and amino acids/oligopeptides	REACTOME pathways	R-HSA-425393	107	4	10285	31	SLC4A4,SLC1A2,AHCYL2,SLC1A3
2.888e-04	-8.15	EDTRNSPORT	prints domains	PR00173	7	2	5227	20	SLC1A2,SLC1A3
3.013e-04	-8.11	neuron projection morphogenesis	biological process	GO:0048812	486	7	18204	49	CTNNA2,BMPR1B,PTPRZ1,PREX2,GPM6A,NRXN1,TNIK
3.129e-04	-8.07	angiosarcoma	COSMIC cancer mutations	angiosarcoma	2192	16	16828	49	PCDH9,SOX5,MAML2,HPSE2,RYR3,FBXL7,GPM6A,GPC5,COL5A3,LSAMP,NKAIN3,CDH20,SLC1A2,SLC1A3,PREX2,PTPRZ1
3.129e-04	-8.07	soft_tissue-blood_vessel-angiosarcoma	COSMIC cancer mutations	soft_tissue-blood_vessel-angiosarcoma	2192	16	16828	49	PCDH9,RYR3,HPSE2,SOX5,MAML2,GPM6A,GPC5,FBXL7,COL5A3,LSAMP,CDH20,SLC1A2,PTPRZ1,PREX2,SLC1A3,NKAIN3
3.150e-04	-8.06	cellular response to cocaine	biological process	GO:0071314	10	2	18204	49	SLC1A3,SLC1A2
3.205e-04	-8.05	plasma membrane bounded cell projection morphogenesis	biological process	GO:0120039	491	7	18204	49	NRXN1,CTNNA2,PREX2,TNIK,GPM6A,BMPR1B,PTPRZ1
3.244e-04	-8.03	bone	COSMIC cancer mutations	bone	8157	36	16828	49	HPSE2,RYR3,TNIK,SOX5,RORA,QKI,SPARCL1,GPC5,ZBTB20,CST3,DTNA,GPM6A,GLUL,COL5A3,PTPRZ1,PON2,NPAS3,NKAIN3,MAML2,PCDH9,FGFR3,PTGDS,ATP13A4,NRXN1,GLIS3,HIF3A,TRPS1,ATP1A2,PARD3B,AHCYL2,SLC4A4,LSAMP,CPE,PAMR1,SLC1A3,PREX2
3.346e-04	-8.00	central_nervous_system-brainstem-glioma-oligoastrocytoma_Grade_III	COSMIC cancer mutations	central_nervous_system-brainstem-glioma-oligoastrocytoma_Grade_III	114	4	16828	49	SLC1A2,RYR3,SOX5,PREX2
3.407e-04	-7.98	cell projection morphogenesis	biological process	GO:0048858	496	7	18204	49	GPM6A,TNIK,PREX2,PTPRZ1,BMPR1B,NRXN1,CTNNA2
3.488e-04	-7.96	pharynx	COSMIC cancer mutations	pharynx	2696	18	16828	49	SLC4A4,CLU,ATP1A2,PARD3B,SLC1A2,NHSL1,NPAS3,PREX2,PTPRZ1,PITPNC1,FGFR3,PCDH9,ATP13A4,RYR3,QKI,DTNA,GPC5,NFIA
3.844e-04	-7.86	L-aspartate transmembrane transport	biological process	GO:0070778	11	2	18204	49	SLC1A2,SLC1A3
3.844e-04	-7.86	L-glutamate import across plasma membrane	biological process	GO:0098712	11	2	18204	49	SLC1A3,SLC1A2
3.898e-04	-7.85	Bicarbonate transporters	REACTOME pathways	R-HSA-425381	10	2	10285	31	AHCYL2,SLC4A4
3.906e-04	-7.85	regulation of chondrocyte differentiation	biological process	GO:0032330	53	3	18204	49	TRPS1,SOX5,BMPR1B
4.023e-04	-7.82	CSTL1 (cystatin like 1)	protein interactions	128817	56	3	19454	50	CPE,CLU,APOE
4.118e-04	-7.79	chronic_lymphocytic_leukaemia-small_lymphocytic_lymphoma	COSMIC cancer mutations	chronic_lymphocytic_leukaemia-small_lymphocytic_lymphoma	3511	21	16828	49	CPE,PAMR1,BMPR1B,LSAMP,SLC4A4,CLU,PARD3B,PITPNC1,NPAS3,SLC1A3,PTPRZ1,PREX2,PCDH9,ZNRF3,HPSE2,RYR3,TNIK,FBXL7,DTNA,GPC5,MSI2
4.118e-04	-7.79	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-chronic_lymphocytic_leukaemia-small_lymphocytic_lymphoma	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-chronic_lymphocytic_leukaemia-small_lymphocytic_lymphoma	3511	21	16828	49	DTNA,GPC5,MSI2,FBXL7,PCDH9,ZNRF3,RYR3,HPSE2,TNIK,NPAS3,PTPRZ1,SLC1A3,PREX2,PITPNC1,SLC4A4,CLU,PARD3B,PAMR1,CPE,BMPR1B,LSAMP
4.203e-04	-7.77	TREM2 (triggering receptor expressed on myeloid cells 2)	protein interactions	54209	12	2	19454	50	CLU,APOE
4.218e-04	-7.77	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-mantle_cell_lymphoma	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-mantle_cell_lymphoma	2737	18	16828	49	ZNRF3,PCDH9,MAML2,SOX5,RYR3,HPSE2,GPM6A,GPC5,TRPS1,HIF3A,FBXL7,PARD3B,CPE,LSAMP,SLC1A2,SLC1A3,PREX2,NKAIN3
4.258e-04	-7.76	haematopoietic_and_lymphoid_tissue-lymph_node-lymphoid_neoplasm-mantle_cell_lymphoma	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue-lymph_node-lymphoid_neoplasm-mantle_cell_lymphoma	476	7	16828	49	LSAMP,MAML2,RYR3,GPC5,GPM6A,ATP13A4,PCDH9
4.605e-04	-7.68	auditory behavior	biological process	GO:0031223	12	2	18204	49	SLC1A3,NRXN1
4.796e-04	-7.64	neuron projection development	biological process	GO:0031175	693	8	18204	49	PREX2,GPM6A,TNIK,NRXN1,BMPR1B,CTNNA2,APOE,PTPRZ1
4.928e-04	-7.62	NAKATPASE	prints domains	PR00121	9	2	5227	20	ATP13A4,ATP1A2
5.225e-04	-7.56	extracellular matrix	cellular component	GO:0031012	559	7	19108	49	PTPRZ1,APOE,HPSE2,CLU,GPC5,COL5A3,SPARCL1
5.281e-04	-7.55	external encapsulating structure	cellular component	GO:0030312	560	7	19108	49	COL5A3,SPARCL1,CLU,HPSE2,GPC5,PTPRZ1,APOE
5.428e-04	-7.52	neurotransmitter transport	biological process	GO:0006836	140	4	18204	49	NRXN1,SLC1A3,SLC1A2,ATP1A2
5.432e-04	-7.52	negative regulation of amyloid fibril formation	biological process	GO:1905907	13	2	18204	49	CLU,APOE
5.776e-04	-7.46	C9 (complement C9)	protein interactions	735	14	2	19454	50	APOE,CLU
5.776e-04	-7.46	PLXNA4 (plexin A4)	protein interactions	91584	14	2	19454	50	GPM6A,CLU
5.891e-04	-7.44	L-glutamate transmembrane transporter activity	molecular function	GO:0005313	14	2	18094	47	SLC1A2,SLC1A3
6.327e-04	-7.37	sodium ion export across plasma membrane	biological process	GO:0036376	14	2	18204	49	SLC4A4,ATP1A2
6.327e-04	-7.37	mechanosensory behavior	biological process	GO:0007638	14	2	18204	49	NRXN1,SLC1A3
6.356e-04	-7.36	adult behavior	biological process	GO:0030534	146	4	18204	49	SLC1A2,ATP1A2,NRXN1,PREX2
6.518e-04	-7.34	cell population proliferation	biological process	GO:0008283	726	8	18204	49	GLUL,FGFR3,CLU,NFIA,ZNRF3,SOX5,HPSE2,RORA
6.556e-04	-7.33	Ig_3	pfam domains	PF13927	141	4	17795	50	FGFR3,HEPACAM,NTM,LSAMP
6.654e-04	-7.32	RNASE13 (ribonuclease A family member 13 (inactive))	protein interactions	440163	15	2	19454	50	CPE,CLU
6.850e-04	-7.29	scalp	COSMIC cancer mutations	scalp	2110	15	16828	49	SLC4A4,ATP1A2,COL5A3,LSAMP,PREX2,PTPRZ1,FGFR3,RORA,ATP13A4,NTM,SOX5,GPC5,NRXN1,TRPS1,NFIA
7.003e-04	-7.26	active monoatomic ion transmembrane transporter activity	molecular function	GO:0022853	274	5	18094	47	SLC1A2,SLC4A4,ATP13A4,ATP1A2,SLC1A3
7.170e-04	-7.24	right_upper_lobe	COSMIC cancer mutations	right_upper_lobe	10376	41	16828	49	NKAIN3,SLC1A2,PON2,NPAS3,PTPRZ1,COL5A3,BMPR1B,GLUL,NFIA,FBXL7,DTNA,GPM6A,GPC5,ZBTB20,RORA,TNIK,RYR3,HPSE2,SOX5,PITPNC1,CDH20,PREX2,SLC1A3,APOE,PAMR1,CPE,LSAMP,AHCYL2,SLC4A4,ATP1A2,PARD3B,HEPACAM,TRPS1,HIF3A,GLIS3,NRXN1,FGFR3,PCDH9,ZNRF3,ATP13A4,NTM
7.170e-04	-7.24	lung-right_upper_lobe-carcinoma-adenocarcinoma	COSMIC cancer mutations	lung-right_upper_lobe-carcinoma-adenocarcinoma	10376	41	16828	49	LSAMP,CPE,PAMR1,APOE,PARD3B,ATP1A2,SLC4A4,AHCYL2,PITPNC1,PREX2,SLC1A3,CDH20,NTM,ATP13A4,ZNRF3,PCDH9,FGFR3,HIF3A,HEPACAM,TRPS1,NRXN1,GLIS3,BMPR1B,COL5A3,GLUL,NKAIN3,PTPRZ1,NPAS3,SLC1A2,PON2,SOX5,HPSE2,TNIK,RYR3,RORA,FBXL7,NFIA,ZBTB20,GPC5,GPM6A,DTNA
7.454e-04	-7.20	sodium ion transmembrane transporter activity	molecular function	GO:0015081	158	4	18094	47	ATP1A2,SLC1A2,SLC4A4,SLC1A3
7.502e-04	-7.20	mast_cell_neoplasm	COSMIC cancer mutations	mast_cell_neoplasm	248	5	16828	49	NFIA,HPSE2,GPC5,NPAS3,PCDH9
7.502e-04	-7.20	haematopoietic_and_lymphoid_tissue-haematopoietic_neoplasm-mast_cell_neoplasm	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue-haematopoietic_neoplasm-mast_cell_neoplasm	248	5	16828	49	GPC5,HPSE2,PCDH9,NPAS3,NFIA
7.549e-04	-7.19	collagen-containing extracellular matrix	cellular component	GO:0062023	428	6	19108	49	CLU,GPC5,COL5A3,SPARCL1,PTPRZ1,APOE
8.086e-04	-7.12	human chr3q13.31	chromosome location	human chr3q13.31	22	2	26134	50	LSAMP,ZBTB20
8.133e-04	-7.11	vascular process in circulatory system	biological process	GO:0003018	273	5	18204	49	SLC1A3,ATP1A2,SLC4A4,SLC1A2,APOE
8.315e-04	-7.09	locomotory exploration behavior	biological process	GO:0035641	16	2	18204	49	ATP1A2,APOE
8.727e-04	-7.04	intracellular chemical homeostasis	biological process	GO:0055082	581	7	18204	49	ATP13A4,RYR3,ZBTB20,APOE,SLC4A4,ATP1A2,SLC1A3
9.296e-04	-6.98	alveolar	COSMIC cancer mutations	alveolar	2414	16	16828	49	NHSL1,NPAS3,CDH20,PON2,PREX2,SLC1A3,PARD3B,CLU,PAMR1,APOE,NFIA,TRPS1,ZNRF3,FGFR3,RYR3,SPARCL1
9.296e-04	-6.98	soft_tissue-striated_muscle-rhabdomyosarcoma-alveolar	COSMIC cancer mutations	soft_tissue-striated_muscle-rhabdomyosarcoma-alveolar	2414	16	16828	49	TRPS1,NFIA,RYR3,FGFR3,ZNRF3,SPARCL1,SLC1A3,PREX2,PON2,CDH20,NHSL1,NPAS3,CLU,PARD3B,APOE,PAMR1
9.407e-04	-6.97	regulation of amyloid fibril formation	biological process	GO:1905906	17	2	18204	49	CLU,APOE
9.407e-04	-6.97	reverse cholesterol transport	biological process	GO:0043691	17	2	18204	49	CLU,APOE
9.443e-04	-6.97	autonomic_ganglia	COSMIC cancer mutations	autonomic_ganglia	4005	22	16828	49	SLC4A4,PARD3B,ATP1A2,PITPNC1,NHSL1,PREX2,ZNRF3,FGFR3,PCDH9,MAML2,TRPS1,HIF3A,GLIS3,COL5A3,NPAS3,SLC1A2,PTPRZ1,TNIK,RYR3,NFIA,FBXL7,GPM6A
9.444e-04	-6.96	metal ion transmembrane transporter activity	molecular function	GO:0046873	442	6	18094	47	ATP1A2,SLC1A2,SLC4A4,GPM6A,RYR3,SLC1A3
9.592e-04	-6.95	humerus	COSMIC cancer mutations	humerus	546	7	16828	49	GPC5,GPM6A,NKAIN3,HIF3A,PARD3B,SOX5,AHCYL2
9.696e-04	-6.94	intracellular monoatomic cation homeostasis	biological process	GO:0030003	428	6	18204	49	ATP13A4,RYR3,SLC4A4,ATP1A2,APOE,SLC1A3
9.763e-04	-6.93	oligoastrocytoma_Grade_III	COSMIC cancer mutations	oligoastrocytoma_Grade_III	263	5	16828	49	SOX5,PREX2,RYR3,SLC1A2,FGFR3
9.840e-04	-6.92	heparan sulfate proteoglycan binding	molecular function	GO:0043395	18	2	18094	47	APOE,HPSE2
9.840e-04	-6.92	acidic amino acid transmembrane transporter activity	molecular function	GO:0015172	18	2	18094	47	SLC1A2,SLC1A3
9.985e-04	-6.91	regulation of cartilage development	biological process	GO:0061035	73	3	18204	49	SOX5,TRPS1,BMPR1B
1.022e-03	-6.89	Htt (huntingtin)	protein interactions	15194	77	3	19454	50	GPM6A,LSAMP,NTM
1.063e-03	-6.85	ATPase_P-typ_cation-transptr_N	interpro domains	IPR004014	18	2	18521	50	ATP13A4,ATP1A2
1.075e-03	-6.84	nodular	COSMIC cancer mutations	nodular	1515	12	16828	49	CPE,ATP1A2,SLC4A4,PREX2,PTPRZ1,CDH20,NPAS3,SPARCL1,FGFR3,ATP13A4,HIF3A,GLIS3
1.079e-03	-6.83	intracellular monoatomic ion homeostasis	biological process	GO:0006873	437	6	18204	49	SLC1A3,ATP13A4,RYR3,APOE,ATP1A2,SLC4A4
1.124e-03	-6.79	monoatomic cation transmembrane transporter activity	molecular function	GO:0008324	630	7	18094	47	SLC1A3,ATP1A2,GPM6A,SLC1A2,ATP13A4,SLC4A4,RYR3
1.150e-03	-6.77	Cation_ATPase_N	pfam domains	PF00690	18	2	17795	50	ATP13A4,ATP1A2
1.158e-03	-6.76	cell morphogenesis involved in neuron differentiation	biological process	GO:0048667	443	6	18204	49	PTPRZ1,CTNNA2,BMPR1B,NRXN1,PREX2,SLC1A3
1.173e-03	-6.75	solute:sodium symporter activity	molecular function	GO:0015370	80	3	18094	47	SLC1A2,SLC4A4,SLC1A3
1.179e-03	-6.74	cartilage condensation	biological process	GO:0001502	19	2	18204	49	SOX5,BMPR1B
1.179e-03	-6.74	regulation of amyloid-beta clearance	biological process	GO:1900221	19	2	18204	49	CLU,APOE
1.186e-03	-6.74	PAS_fold	interpro domains	IPR013767	19	2	18521	50	NPAS3,HIF3A
1.190e-03	-6.73	endoplasmic reticulum lumen	cellular component	GO:0005788	312	5	19108	49	COL5A3,SPARCL1,CST3,CLU,APOE
1.194e-03	-6.73	PDZD2 (PDZ domain containing 2)	protein interactions	23037	20	2	19454	50	NRXN1,CST3
1.196e-03	-6.73	cartilage development	biological process	GO:0051216	173	4	18204	49	SOX5,FGFR3,NFIA,BMPR1B
1.226e-03	-6.70	GSC (goosecoid homeobox)	protein interactions	145258	82	3	19454	50	TRPS1,SOX5,NFIA
1.261e-03	-6.68	behavior	biological process	GO:0007610	619	7	18204	49	NRXN1,PREX2,SLC1A3,SLC1A2,PTPRZ1,APOE,ATP1A2
1.283e-03	-6.66	PAS	pfam domains	PF00989	19	2	17795	50	HIF3A,NPAS3
1.307e-03	-6.64	positive regulation of chondrocyte differentiation	biological process	GO:0032332	20	2	18204	49	BMPR1B,SOX5
1.307e-03	-6.64	aspartate transmembrane transport	biological process	GO:0015810	20	2	18204	49	SLC1A3,SLC1A2
1.318e-03	-6.63	HTR2A (5-hydroxytryptamine receptor 2A)	protein interactions	3356	21	2	19454	50	GLUL,PON2
1.383e-03	-6.58	trunk	COSMIC cancer mutations	trunk	3554	20	16828	49	ATP1A2,LSAMP,CPE,PTPRZ1,PREX2,SLC1A3,NPAS3,CDH20,MAML2,SOX5,HPSE2,RYR3,ATP13A4,PCDH9,FGFR3,SPARCL1,NRXN1,GLIS3,HIF3A,TRPS1
1.443e-03	-6.54	cell aggregation	biological process	GO:0098743	21	2	18204	49	BMPR1B,SOX5
1.443e-03	-6.54	positive regulation of glycolytic process	biological process	GO:0045821	21	2	18204	49	SLC4A4,ZBTB20
1.443e-03	-6.54	positive regulation of purine nucleotide catabolic process	biological process	GO:0033123	21	2	18204	49	SLC4A4,ZBTB20
1.443e-03	-6.54	positive regulation of nucleotide catabolic process	biological process	GO:0030813	21	2	18204	49	SLC4A4,ZBTB20
1.499e-03	-6.50	neuronal cell body	cellular component	GO:0043025	489	6	19108	49	NRXN1,BMPR1B,SLC1A3,GPM6A,ATP1A2,APOE
1.550e-03	-6.47	chondrocyte differentiation	biological process	GO:0002062	85	3	18204	49	FGFR3,SOX5,BMPR1B
1.552e-03	-6.47	endoplasmic reticulum	cellular component	GO:0005783	2051	13	19108	49	PTGDS,AHCYL2,NRXN1,CST3,APOE,ATP1A2,CLU,RYR3,ATP13A4,GLUL,COL5A3,FGFR3,SPARCL1
1.582e-03	-6.45	TIMM10B (translocase of inner mitochondrial membrane 10B)	protein interactions	26515	23	2	19454	50	MSI2,HPSE2
1.582e-03	-6.45	Rbm38 (RNA binding motif protein 38)	protein interactions	56190	23	2	19454	50	MSI2,QKI
1.584e-03	-6.45	intracellular sodium ion homeostasis	biological process	GO:0006883	22	2	18204	49	SLC1A3,ATP1A2
1.595e-03	-6.44	amyloid-beta binding	molecular function	GO:0001540	89	3	18094	47	CST3,CLU,APOE
1.614e-03	-6.43	amino acid:sodium symporter activity	molecular function	GO:0005283	23	2	18094	47	SLC1A3,SLC1A2
1.689e-03	-6.38	skin-scalp-carcinoma-squamous_cell_carcinoma	COSMIC cancer mutations	skin-scalp-carcinoma-squamous_cell_carcinoma	1596	12	16828	49	TRPS1,NRXN1,GPC5,ATP13A4,RORA,FGFR3,SOX5,PTPRZ1,COL5A3,LSAMP,SLC4A4,ATP1A2
1.723e-03	-6.36	LNP1 (leukemia NUP98 fusion partner 1)	protein interactions	348801	24	2	19454	50	AHCYL2,GLUL
1.726e-03	-6.36	Cation_ATPase_N	smart domains	SM00831	16	2	9717	38	ATP1A2,ATP13A4
1.757e-03	-6.34	P-type ion transporter activity	molecular function	GO:0015662	24	2	18094	47	ATP1A2,ATP13A4
1.757e-03	-6.34	low-density lipoprotein particle receptor binding	molecular function	GO:0050750	24	2	18094	47	CLU,APOE
1.757e-03	-6.34	P-type transmembrane transporter activity	molecular function	GO:0140358	24	2	18094	47	ATP1A2,ATP13A4
1.758e-03	-6.34	cell development	biological process	GO:0048468	2236	14	18204	49	APOE,CTNNA2,NRXN1,SLC1A3,CLU,QKI,PTPRZ1,RORA,BMPR1B,TNIK,GPM6A,NTM,PREX2,MSI2
1.774e-03	-6.33	bone-humerus-other-chondroblastoma	COSMIC cancer mutations	bone-humerus-other-chondroblastoma	301	5	16828	49	GPM6A,AHCYL2,SOX5,GPC5,NKAIN3
1.781e-03	-6.33	ovary-carcinoma-serous_carcinoma	COSMIC cancer mutations	ovary-carcinoma-serous_carcinoma	10710	41	16828	49	PREX2,SLC1A3,NHSL1,CDH20,LSAMP,CPE,PAMR1,PARD3B,CLU,ATP1A2,SLC4A4,AHCYL2,TRPS1,HEPACAM,NRXN1,GLIS3,NTM,MAML2,PTGDS,ZNRF3,ATP13A4,FGFR3,PCDH9,PTPRZ1,NPAS3,SLC1A2,BMPR1B,COL5A3,GLUL,FBXL7,ZBTB20,MSI2,GPC5,DTNA,CST3,QKI,SOX5,RYR3,HPSE2,TNIK,RORA
1.782e-03	-6.33	HS-GAG degradation	REACTOME pathways	R-HSA-2024096	21	2	10285	31	GPC5,HPSE2
1.808e-03	-6.32	lung-carcinoma-small_cell_carcinoma	COSMIC cancer mutations	lung-carcinoma-small_cell_carcinoma	9908	39	16828	49	MAML2,NTM,ZNRF3,ATP13A4,PCDH9,FGFR3,HIF3A,TRPS1,HEPACAM,NRXN1,CPE,PAMR1,PARD3B,CLU,ATP1A2,AHCYL2,SLC4A4,PITPNC1,PREX2,CDH20,SPARCL1,QKI,SOX5,TNIK,HPSE2,RYR3,RORA,FBXL7,NFIA,MSI2,GPC5,GPM6A,DTNA,CST3,BMPR1B,COL5A3,NKAIN3,PTPRZ1,NPAS3
1.831e-03	-6.30	small_cell_carcinoma	COSMIC cancer mutations	small_cell_carcinoma	9913	39	16828	49	NFIA,FBXL7,GPM6A,DTNA,CST3,MSI2,GPC5,SPARCL1,QKI,RORA,SOX5,HPSE2,TNIK,RYR3,NKAIN3,NPAS3,PTPRZ1,COL5A3,BMPR1B,TRPS1,HEPACAM,HIF3A,NRXN1,ZNRF3,ATP13A4,PCDH9,FGFR3,NTM,MAML2,PITPNC1,CDH20,PREX2,CPE,PAMR1,SLC4A4,AHCYL2,PARD3B,CLU,ATP1A2
1.848e-03	-6.29	cell surface	cellular component	GO:0009986	896	8	19108	49	FGFR3,SLC1A3,NRXN1,CLU,SLC1A2,GPC5,ATP1A2,SLC4A4
1.911e-03	-6.26	cell-cell junction	cellular component	GO:0005911	513	6	19108	49	CTNNA2,PARD3B,HEPACAM,ATP1A2,PCDH9,CDH20
1.913e-03	-6.26	human chr15q13.3-q14	chromosome location	human chr15q13.3-q14	1	1	26134	50	RYR3
1.913e-03	-6.26	human chr3q26.2-q26.31	chromosome location	human chr3q26.2-q26.31	1	1	26134	50	TNIK
1.960e-03	-6.23	synapse organization	biological process	GO:0050808	333	5	18204	49	GPM6A,NRXN1,SPARCL1,APOE,NFIA
1.987e-03	-6.22	BTG3 (BTG anti-proliferation factor 3)	protein interactions	10950	97	3	19454	50	GLUL,CLU,SPARCL1
2.013e-03	-6.21	high-density lipoprotein particle	cellular component	GO:0034364	26	2	19108	49	APOE,CLU
2.021e-03	-6.20	skin-face-malignant_melanoma-lentigo_maligna	COSMIC cancer mutations	skin-face-malignant_melanoma-lentigo_maligna	23	2	16828	49	FGFR3,PREX2
2.047e-03	-6.19	L-glutamate transmembrane transport	biological process	GO:0015813	25	2	18204	49	SLC1A2,SLC1A3
2.135e-03	-6.15	carcinoid-endocrine_tumour	COSMIC cancer mutations	carcinoid-endocrine_tumour	7752	33	16828	49	PCDH9,FGFR3,ATP13A4,MAML2,GLIS3,TRPS1,AHCYL2,SLC4A4,ATP1A2,CLU,APOE,CPE,PAMR1,LSAMP,CDH20,NHSL1,PREX2,SLC1A3,RORA,HPSE2,TNIK,RYR3,SOX5,QKI,GPM6A,GPC5,FBXL7,COL5A3,BMPR1B,PON2,SLC1A2,PTPRZ1,NKAIN3
2.152e-03	-6.14	extrinsic component of plasma membrane	cellular component	GO:0019897	100	3	19108	49	CTNNA2,CDH20,DTNA
2.161e-03	-6.14	cell projection	cellular component	GO:0042995	2398	14	19108	49	AHCYL2,CTNNA2,DTNA,GPM6A,NRXN1,SLC1A3,APOE,PCDH9,HEPACAM,ATP1A2,SLC1A2,CLU,GLUL,BMPR1B
2.181e-03	-6.13	MBNL2 (muscleblind like splicing regulator 2)	protein interactions	10150	27	2	19454	50	MSI2,QKI
2.214e-03	-6.11	C4-dicarboxylate transport	biological process	GO:0015740	26	2	18204	49	SLC1A3,SLC1A2
2.217e-03	-6.11	glutamine biosynthesis	BIOCYC pathways	HUMAN_GLNSYN-PWY	1	1	902	2	GLUL
2.217e-03	-6.11	L-glutamine biosynthesis I	BIOCYC pathways	META_GLNSYN-PWY	1	1	902	2	GLUL
2.217e-03	-6.11	glutamate dependent acid resistance	BIOCYC pathways	HUMAN_PWY0-1305	1	1	902	2	GLUL
2.220e-03	-6.11	autonomic_ganglia-neuroblastoma	COSMIC cancer mutations	autonomic_ganglia-neuroblastoma	3970	21	16828	49	PITPNC1,NPAS3,SLC1A2,PTPRZ1,PREX2,COL5A3,SLC4A4,PARD3B,ATP1A2,NFIA,TRPS1,HIF3A,FBXL7,GPM6A,GLIS3,ZNRF3,PCDH9,FGFR3,MAML2,RYR3,TNIK
2.222e-03	-6.11	upper_aerodigestive_tract-pharynx-carcinoma-nasopharyngeal_carcinoma	COSMIC cancer mutations	upper_aerodigestive_tract-pharynx-carcinoma-nasopharyngeal_carcinoma	1425	11	16828	49	PREX2,SLC1A2,NHSL1,PITPNC1,NFIA,CLU,ATP1A2,SLC4A4,FGFR3,ATP13A4,QKI
2.222e-03	-6.11	nasopharyngeal_carcinoma	COSMIC cancer mutations	nasopharyngeal_carcinoma	1425	11	16828	49	PITPNC1,PREX2,SLC1A2,NHSL1,CLU,ATP1A2,SLC4A4,NFIA,QKI,FGFR3,ATP13A4
2.227e-03	-6.11	neuroblastoma	COSMIC cancer mutations	neuroblastoma	3971	21	16828	49	ZNRF3,PCDH9,FGFR3,MAML2,TNIK,RYR3,NFIA,TRPS1,HIF3A,FBXL7,GLIS3,GPM6A,COL5A3,SLC4A4,PARD3B,ATP1A2,PITPNC1,NPAS3,SLC1A2,PTPRZ1,PREX2
2.247e-03	-6.10	PROKAR_LIPOPROTEIN	prosite domains	PS51257	76	3	12186	42	CPE,APOE,GLIS3
2.250e-03	-6.10	monoatomic cation homeostasis	biological process	GO:0055080	505	6	18204	49	ATP1A2,SLC4A4,APOE,ATP13A4,RYR3,SLC1A3
2.304e-03	-6.07	oesophagus-carcinoma	COSMIC cancer mutations	oesophagus-carcinoma	4269	22	16828	49	SLC4A4,PARD3B,COL5A3,NHSL1,CDH20,PTPRZ1,PREX2,ATP13A4,PTGDS,PCDH9,FGFR3,NTM,SOX5,RYR3,HPSE2,TNIK,GPM6A,ZBTB20,NFIA,TRPS1,FBXL7,HIF3A
2.324e-03	-6.06	cellular homeostasis	biological process	GO:0019725	689	7	18204	49	ZBTB20,RYR3,SLC1A3,ATP13A4,APOE,ATP1A2,SLC4A4
2.328e-03	-6.06	Glutamate Neurotransmitter Release Cycle	REACTOME pathways	R-HSA-210500	24	2	10285	31	SLC1A2,SLC1A3
2.396e-03	-6.03	Proximal tubule bicarbonate reclamation	KEGG pathways	ko04964	23	2	7161	23	ATP1A2,SLC4A4
2.396e-03	-6.03	Proximal tubule bicarbonate reclamation	KEGG pathways	hsa04964	23	2	7161	23	ATP1A2,SLC4A4
2.467e-03	-6.00	response to alkaloid	biological process	GO:0043279	100	3	18204	49	SLC1A2,SLC1A3,RYR3
2.482e-03	-6.00	monoatomic ion homeostasis	biological process	GO:0050801	515	6	18204	49	ATP1A2,SLC4A4,APOE,RYR3,ATP13A4,SLC1A3
2.564e-03	-5.97	lipoprotein particle receptor binding	molecular function	GO:0070325	29	2	18094	47	CLU,APOE
2.564e-03	-5.97	amino acid:monoatomic cation symporter activity	molecular function	GO:0005416	29	2	18094	47	SLC1A3,SLC1A2
2.564e-03	-5.97	perinuclear endoplasmic reticulum lumen	cellular component	GO:0099020	1	1	19108	49	CLU
2.566e-03	-5.97	glial cell proliferation	biological process	GO:0014009	28	2	18204	49	CLU,NFIA
2.566e-03	-5.97	positive regulation of oligodendrocyte differentiation	biological process	GO:0048714	28	2	18204	49	QKI,PTPRZ1
2.570e-03	-5.96	Hipk3 (homeodomain interacting protein kinase 3)	protein interactions	15259	1	1	19454	50	GLIS3
2.570e-03	-5.96	fgf3.L (fibroblast growth factor 3 L homeolog)	protein interactions	373669	1	1	19454	50	FGFR3
2.570e-03	-5.96	1700006A11Rik (RIKEN cDNA 1700006A11 gene)	protein interactions	71824	1	1	19454	50	BMPR1B
2.570e-03	-5.96	Sytl1 (synaptotagmin-like 1)	protein interactions	269589	1	1	19454	50	NRXN1
2.570e-03	-5.96	Dcaf7 (DDB1 and CUL4 associated factor 7)	protein interactions	71833	1	1	19454	50	BMPR1B
2.570e-03	-5.96	Agtrap (angiotensin II, type I receptor-associated protein)	protein interactions	11610	1	1	19454	50	PITPNC1
2.570e-03	-5.96	Lztr1 (leucine-zipper-like transcriptional regulator, 1)	protein interactions	66863	1	1	19454	50	BMPR1B
2.570e-03	-5.96	Isl1 (ISL1 transcription factor, LIM/homeodomain)	protein interactions	16392	1	1	19454	50	GLIS3
2.570e-03	-5.96	Sh2b1 (SH2B adaptor protein 1)	protein interactions	20399	1	1	19454	50	FGFR3
2.593e-03	-5.95	Calcium-transporting ATPase, transmembrane domain	gene3d domains	1.20.1110.10	25	2	14470	44	ATP13A4,ATP1A2
2.598e-03	-5.95	metal chelating activity	molecular function	GO:0046911	1	1	18094	47	APOE
2.598e-03	-5.95	internal N(7)-methylguanine-containing RNA reader activity	molecular function	GO:0160089	1	1	18094	47	QKI
2.645e-03	-5.94	tibia	COSMIC cancer mutations	tibia	836	8	16828	49	LSAMP,NKAIN3,CPE,QKI,PREX2,TNIK,GPM6A,FGFR3
2.692e-03	-5.92	regulation of transport across blood-brain barrier	biological process	GO:0150200	1	1	18204	49	APOE
2.692e-03	-5.92	positive regulation of transport across blood-brain barrier	biological process	GO:0150201	1	1	18204	49	APOE
2.692e-03	-5.92	regulation of cellular response to very-low-density lipoprotein particle stimulus	biological process	GO:1905890	1	1	18204	49	APOE
2.692e-03	-5.92	regulation of heparan sulfate proteoglycan binding	biological process	GO:1905858	1	1	18204	49	APOE
2.692e-03	-5.92	positive regulation of neurofibrillary tangle assembly	biological process	GO:1902998	1	1	18204	49	CLU
2.692e-03	-5.92	negative regulation of calcium:sodium antiporter activity	biological process	GO:1903280	1	1	18204	49	ATP1A2
2.692e-03	-5.92	olfactory cortex development	biological process	GO:0021989	1	1	18204	49	ATP1A2
2.692e-03	-5.92	negative regulation of collagen catabolic process	biological process	GO:0010711	1	1	18204	49	CST3
2.692e-03	-5.92	regulation of lipid transport across blood-brain barrier	biological process	GO:1903000	1	1	18204	49	APOE
2.692e-03	-5.92	regulation of neuronal signal transduction	biological process	GO:1902847	1	1	18204	49	CLU
2.692e-03	-5.92	positive regulation of lipid transport across blood-brain barrier	biological process	GO:1903002	1	1	18204	49	APOE
2.692e-03	-5.92	negative regulation of elastin catabolic process	biological process	GO:0060311	1	1	18204	49	CST3
2.692e-03	-5.92	intermediate-density lipoprotein particle clearance	biological process	GO:0071831	1	1	18204	49	APOE
2.692e-03	-5.92	positive regulation of heparan sulfate proteoglycan binding	biological process	GO:1905860	1	1	18204	49	APOE
2.692e-03	-5.92	oesophagus-carcinoma-squamous_cell_carcinoma	COSMIC cancer mutations	oesophagus-carcinoma-squamous_cell_carcinoma	6486	29	16828	49	HEPACAM,TRPS1,HIF3A,GLIS3,NRXN1,PCDH9,FGFR3,ATP13A4,MAML2,PITPNC1,PREX2,CPE,SLC4A4,ATP1A2,PARD3B,FBXL7,GPM6A,GPC5,ZBTB20,SPARCL1,HPSE2,RYR3,TNIK,SOX5,NPAS3,PTPRZ1,COL5A3,BMPR1B,GLUL
2.698e-03	-5.92	EN1 (engrailed homeobox 1)	protein interactions	2019	108	3	19454	50	TRPS1,AHCYL2,NFIA
2.699e-03	-5.92	beta-catenin binding	molecular function	GO:0008013	107	3	18094	47	CTNNA2,CDH20,RORA
2.700e-03	-5.91	Clusterin_CS	interpro domains	IPR033986	1	1	18521	50	CLU
2.700e-03	-5.91	Rex2_DEP_1	interpro domains	IPR037367	1	1	18521	50	PREX2
2.700e-03	-5.91	STAR_dimer	interpro domains	IPR032377	1	1	18521	50	QKI
2.700e-03	-5.91	SPARC-like_p1	interpro domains	IPR016359	1	1	18521	50	SPARCL1
2.700e-03	-5.91	M14_CPE_CPD	interpro domains	IPR034232	1	1	18521	50	CPE
2.700e-03	-5.91	Gln_synth_N_conserv_site	interpro domains	IPR027302	1	1	18521	50	GLUL
2.700e-03	-5.91	Quaking_NLS	interpro domains	IPR032367	1	1	18521	50	QKI
2.700e-03	-5.91	Gln_synth_gly_rich_site	interpro domains	IPR027303	1	1	18521	50	GLUL
2.700e-03	-5.91	MAML2_TAD	interpro domains	IPR048452	1	1	18521	50	MAML2
2.700e-03	-5.91	Clusterin	interpro domains	IPR016016	1	1	18521	50	CLU
2.700e-03	-5.91	TRPS1	interpro domains	IPR028440	1	1	18521	50	TRPS1
2.700e-03	-5.91	ZNRF3_Znf_RING	interpro domains	IPR045903	1	1	18521	50	ZNRF3
2.709e-03	-5.91	large_intestine-caecum-carcinoma-adenocarcinoma	COSMIC cancer mutations	large_intestine-caecum-carcinoma-adenocarcinoma	14236	48	16828	49	RORA,RYR3,TNIK,HPSE2,QKI,GPM6A,ZBTB20,GPC5,NFIA,GLUL,BMPR1B,NPAS3,SLC1A2,PTPRZ1,NKAIN3,PTGDS,ZNRF3,PCDH9,MAML2,GLIS3,NRXN1,PARD3B,CPE,APOE,SLC1A3,PREX2,SOX5,SPARCL1,DTNA,CST3,FBXL7,COL5A3,PON2,ATP13A4,FGFR3,NTM,HEPACAM,TRPS1,HIF3A,AHCYL2,SLC4A4,CLU,ATP1A2,PAMR1,LSAMP,NHSL1,CDH20,PITPNC1
2.751e-03	-5.90	negative regulation of amyloid-beta formation	biological process	GO:1902430	29	2	18204	49	APOE,CLU
2.751e-03	-5.90	postsynaptic membrane organization	biological process	GO:0001941	29	2	18204	49	APOE,NRXN1
2.809e-03	-5.87	caecum	COSMIC cancer mutations	caecum	14248	48	16828	49	QKI,RORA,TNIK,RYR3,HPSE2,NFIA,GPM6A,GPC5,ZBTB20,BMPR1B,GLUL,NKAIN3,SLC1A2,NPAS3,PTPRZ1,PCDH9,PTGDS,ZNRF3,MAML2,GLIS3,NRXN1,APOE,CPE,PARD3B,SLC1A3,PREX2,SPARCL1,SOX5,FBXL7,DTNA,CST3,COL5A3,PON2,FGFR3,ATP13A4,NTM,TRPS1,HEPACAM,HIF3A,PAMR1,LSAMP,SLC4A4,AHCYL2,CLU,ATP1A2,PITPNC1,CDH20,NHSL1
2.810e-03	-5.87	MAML2_TAD	pfam domains	PF20804	1	1	17795	50	MAML2
2.810e-03	-5.87	Gln-synt_N	pfam domains	PF03951	1	1	17795	50	GLUL
2.810e-03	-5.87	STAR_dimer	pfam domains	PF16544	1	1	17795	50	QKI
2.810e-03	-5.87	Quaking_NLS	pfam domains	PF16551	1	1	17795	50	QKI
2.810e-03	-5.87	FGFR3_TM	pfam domains	PF21165	1	1	17795	50	FGFR3
2.827e-03	-5.87	glial cell differentiation	biological process	GO:0010001	219	4	18204	49	NFIA,QKI,PTPRZ1,CLU
2.828e-03	-5.87	chemical homeostasis	biological process	GO:0048878	914	8	18204	49	SLC1A3,RORA,ZBTB20,ATP13A4,RYR3,APOE,ATP1A2,SLC4A4
2.834e-03	-5.87	neural precursor cell proliferation	biological process	GO:0061351	105	3	18204	49	SOX5,RORA,NFIA
2.834e-03	-5.87	Salivary secretion	KEGG pathways	hsa04970	90	3	7161	23	RYR3,ATP1A2,CST3
2.834e-03	-5.87	Salivary secretion	KEGG pathways	ko04970	90	3	7161	23	ATP1A2,RYR3,CST3
2.842e-03	-5.86	metal ion binding	molecular function	GO:0046872	4239	20	18094	47	PCDH9,CPE,ATP13A4,PAMR1,ZBTB20,SLC1A3,BMPR1B,PON2,TRPS1,RORA,RYR3,SLC1A2,APOE,SPARCL1,NRXN1,ATP1A2,ZNRF3,DTNA,GLIS3,GLUL
2.857e-03	-5.86	catenin complex	cellular component	GO:0016342	31	2	19108	49	CDH20,CTNNA2
2.906e-03	-5.84	bone-tibia-other-chondroblastoma	COSMIC cancer mutations	bone-tibia-other-chondroblastoma	98	3	16828	49	LSAMP,NKAIN3,GPM6A
2.916e-03	-5.84	cell junction organization	biological process	GO:0034330	532	6	18204	49	SPARCL1,APOE,NFIA,GPM6A,NRXN1,CDH20
2.942e-03	-5.83	L-glutamate import	biological process	GO:0051938	30	2	18204	49	SLC1A2,SLC1A3
2.991e-03	-5.81	TBR1 (T-box brain transcription factor 1)	protein interactions	10716	112	3	19454	50	NFIA,SOX5,TRPS1
3.014e-03	-5.80	t(4;14) translocations of FGFR3	REACTOME pathways	R-HSA-2033515	1	1	10285	31	FGFR3
3.041e-03	-5.80	-	gene3d domains	1.20.5.4010	1	1	14470	44	QKI
3.041e-03	-5.80	-	gene3d domains	6.10.250.1740	1	1	14470	44	FGFR3
3.057e-03	-5.79	NXPH2 (neurexophilin 2)	protein interactions	11249	32	2	19454	50	NRXN1,PCDH9
3.073e-03	-5.78	monoatomic ion transmembrane transporter activity	molecular function	GO:0015075	752	7	18094	47	ATP1A2,GPM6A,ATP13A4,SLC1A2,SLC4A4,RYR3,SLC1A3
3.104e-03	-5.78	upper_aerodigestive_tract	COSMIC cancer mutations	upper_aerodigestive_tract	13181	46	16828	49	ATP13A4,FGFR3,NTM,TRPS1,HEPACAM,HIF3A,PAMR1,LSAMP,AHCYL2,SLC4A4,ATP1A2,CLU,PITPNC1,NHSL1,CDH20,SOX5,FBXL7,CST3,DTNA,MSI2,COL5A3,ZNRF3,PTGDS,PCDH9,MAML2,GLIS3,NRXN1,APOE,PARD3B,SLC1A3,PREX2,QKI,RORA,RYR3,HPSE2,TNIK,NFIA,GPM6A,ZBTB20,GPC5,BMPR1B,GLUL,NKAIN3,NPAS3,SLC1A2,PTPRZ1
3.140e-03	-5.76	negative regulation of amyloid precursor protein catabolic process	biological process	GO:1902992	31	2	18204	49	CLU,APOE
3.177e-03	-5.75	lymphoid_neoplasm	COSMIC cancer mutations	lymphoid_neoplasm	12233	44	16828	49	PARD3B,CPE,PREX2,SLC1A3,MAML2,PCDH9,ZNRF3,NRXN1,GLIS3,BMPR1B,PTPRZ1,SLC1A2,NPAS3,NKAIN3,TNIK,RYR3,HPSE2,RORA,QKI,GPC5,ZBTB20,GPM6A,NFIA,CLU,ATP1A2,SLC4A4,AHCYL2,LSAMP,PAMR1,CDH20,NHSL1,PITPNC1,NTM,FGFR3,ATP13A4,HIF3A,TRPS1,COL5A3,PON2,SOX5,SPARCL1,MSI2,DTNA,FBXL7
3.204e-03	-5.74	cervix-carcinoma-squamous_cell_carcinoma	COSMIC cancer mutations	cervix-carcinoma-squamous_cell_carcinoma	11789	43	16828	49	PON2,COL5A3,DTNA,CST3,FBXL7,SOX5,SPARCL1,CDH20,NHSL1,PITPNC1,ATP1A2,SLC4A4,LSAMP,PAMR1,HIF3A,TRPS1,HEPACAM,NTM,FGFR3,ATP13A4,PTPRZ1,SLC1A2,NPAS3,GLUL,BMPR1B,GPC5,ZBTB20,GPM6A,NFIA,HPSE2,TNIK,RYR3,RORA,QKI,SLC1A3,PREX2,PARD3B,CPE,NRXN1,GLIS3,MAML2,PCDH9,ZNRF3
3.219e-03	-5.74	skin-leg-malignant_melanoma-superficial_spreading	COSMIC cancer mutations	skin-leg-malignant_melanoma-superficial_spreading	210	4	16828	49	COL5A3,SLC4A4,ATP13A4,NTM
3.224e-03	-5.74	human chr11p13	chromosome location	human chr11p13	44	2	26134	50	PAMR1,SLC1A2
3.237e-03	-5.73	cervix	COSMIC cancer mutations	cervix	11793	43	16828	49	CPE,PARD3B,SLC1A3,PREX2,MAML2,PCDH9,ZNRF3,NRXN1,GLIS3,BMPR1B,GLUL,PTPRZ1,SLC1A2,NPAS3,QKI,HPSE2,TNIK,RYR3,RORA,NFIA,GPC5,ZBTB20,GPM6A,LSAMP,PAMR1,ATP1A2,SLC4A4,PITPNC1,CDH20,NHSL1,NTM,FGFR3,ATP13A4,HIF3A,TRPS1,HEPACAM,COL5A3,PON2,SPARCL1,SOX5,FBXL7,CST3,DTNA
3.249e-03	-5.73	VLDLR (very low density lipoprotein receptor)	protein interactions	7436	33	2	19454	50	APOE,CLU
3.253e-03	-5.73	intestinal_adenocarcinoma	COSMIC cancer mutations	intestinal_adenocarcinoma	7225	31	16828	49	PTPRZ1,SLC1A2,NPAS3,COL5A3,GLUL,FBXL7,NFIA,ZBTB20,CST3,QKI,RYR3,HPSE2,SOX5,RORA,PITPNC1,PREX2,CDH20,NHSL1,LSAMP,CLU,ATP1A2,PARD3B,SLC4A4,TRPS1,NRXN1,NTM,MAML2,FGFR3,PCDH9,ATP13A4,ZNRF3
3.253e-03	-5.73	stomach-carcinoma-intestinal_adenocarcinoma	COSMIC cancer mutations	stomach-carcinoma-intestinal_adenocarcinoma	7225	31	16828	49	PTPRZ1,SLC1A2,NPAS3,GLUL,COL5A3,ZBTB20,CST3,FBXL7,NFIA,RYR3,HPSE2,SOX5,RORA,QKI,PREX2,CDH20,NHSL1,PITPNC1,ATP1A2,CLU,PARD3B,SLC4A4,LSAMP,NRXN1,TRPS1,MAML2,NTM,PCDH9,FGFR3,ZNRF3,ATP13A4
3.344e-03	-5.70	positive regulation of ATP metabolic process	biological process	GO:1903580	32	2	18204	49	ZBTB20,SLC4A4
3.344e-03	-5.70	transepithelial transport	biological process	GO:0070633	32	2	18204	49	SLC1A2,SLC1A3
3.344e-03	-5.70	positive regulation of cartilage development	biological process	GO:0061036	32	2	18204	49	SOX5,BMPR1B
3.394e-03	-5.69	Transmembrane transport of small molecules	REACTOME pathways	R-HSA-382551	677	7	10285	31	SLC1A3,ATP13A4,SLC1A2,SLC4A4,RYR3,ATP1A2,AHCYL2
3.415e-03	-5.68	E1-E2_ATPase	pfam domains	PF00122	31	2	17795	50	ATP13A4,ATP1A2
3.430e-03	-5.68	lentigo_maligna	COSMIC cancer mutations	lentigo_maligna	30	2	16828	49	FGFR3,PREX2
3.430e-03	-5.68	skin-malignant_melanoma-acral_lentiginous	COSMIC cancer mutations	skin-malignant_melanoma-acral_lentiginous	30	2	16828	49	PREX2,FGFR3
3.447e-03	-5.67	CLUSTERIN_2	prosite domains	PS00493	1	1	12186	42	CLU
3.447e-03	-5.67	GLNA_1	prosite domains	PS00180	1	1	12186	42	GLUL
3.447e-03	-5.67	GLNA_ATP	prosite domains	PS00181	1	1	12186	42	GLUL
3.447e-03	-5.67	CLUSTERIN_1	prosite domains	PS00492	1	1	12186	42	CLU
3.465e-03	-5.67	CEACAM8 (CEA cell adhesion molecule 8)	protein interactions	1088	118	3	19454	50	APOE,CPE,CLU
3.473e-03	-5.66	solute:monoatomic cation symporter activity	molecular function	GO:0015294	117	3	18094	47	SLC1A3,SLC1A2,SLC4A4
3.476e-03	-5.66	connective tissue development	biological process	GO:0061448	232	4	18204	49	FGFR3,SOX5,NFIA,BMPR1B
3.531e-03	-5.65	transporter activity	molecular function	GO:0005215	1211	9	18094	47	SLC1A3,PITPNC1,APOE,ATP13A4,SLC1A2,SLC4A4,GPM6A,ATP1A2,RYR3
3.548e-03	-5.64	HLA-DPA1 (major histocompatibility complex, class II, DP alpha 1)	protein interactions	3113	119	3	19454	50	APOE,PCDH9,CLU
3.548e-03	-5.64	skin-trunk-malignant_melanoma-nodular	COSMIC cancer mutations	skin-trunk-malignant_melanoma-nodular	1291	10	16828	49	ATP1A2,ATP13A4,SPARCL1,CPE,PTPRZ1,PREX2,NPAS3,GLIS3,CDH20,HIF3A
3.568e-03	-5.64	extracellular region	cellular component	GO:0005576	4350	20	19108	49	CPE,PAMR1,CST3,TNIK,APOE,ATP1A2,SLC4A4,LSAMP,CLU,HPSE2,COL5A3,FGFR3,SPARCL1,PON2,GLUL,PTPRZ1,PTGDS,NTM,GPM6A,GPC5
3.621e-03	-5.62	serous_carcinoma	COSMIC cancer mutations	serous_carcinoma	10987	41	16828	49	NHSL1,CDH20,PREX2,SLC1A3,AHCYL2,SLC4A4,PARD3B,CLU,ATP1A2,PAMR1,CPE,LSAMP,GLIS3,NRXN1,HEPACAM,TRPS1,ATP13A4,PTGDS,ZNRF3,PCDH9,FGFR3,MAML2,NTM,NPAS3,SLC1A2,PTPRZ1,GLUL,COL5A3,BMPR1B,DTNA,CST3,MSI2,ZBTB20,GPC5,FBXL7,RORA,SOX5,TNIK,HPSE2,RYR3,QKI
3.637e-03	-5.62	Cation_ATPase	pfam domains	PF13246	32	2	17795	50	ATP13A4,ATP1A2
3.721e-03	-5.59	organic acid:sodium symporter activity	molecular function	GO:0005343	35	2	18094	47	SLC1A2,SLC1A3
3.769e-03	-5.58	negative regulation of amide metabolic process	biological process	GO:0034249	34	2	18204	49	CLU,APOE
3.769e-03	-5.58	exploration behavior	biological process	GO:0035640	34	2	18204	49	ATP1A2,APOE
3.792e-03	-5.57	PAS	interpro domains	IPR000014	34	2	18521	50	HIF3A,NPAS3
3.792e-03	-5.57	PAS-like_dom_sf	interpro domains	IPR035965	34	2	18521	50	NPAS3,HIF3A
3.817e-03	-5.57	cation binding	molecular function	GO:0043169	4341	20	18094	47	ATP1A2,ZNRF3,APOE,SLC1A2,SPARCL1,NRXN1,RYR3,RORA,GLIS3,GLUL,DTNA,PAMR1,ZBTB20,ATP13A4,CPE,PCDH9,BMPR1B,TRPS1,PON2,SLC1A3
3.839e-03	-5.56	lipoprotein particle	cellular component	GO:1990777	36	2	19108	49	APOE,CLU
3.839e-03	-5.56	plasma lipoprotein particle	cellular component	GO:0034358	36	2	19108	49	CLU,APOE
3.857e-03	-5.56	ZNRF1 (zinc and ring finger 1)	protein interactions	84937	36	2	19454	50	GLUL,ATP1A2
3.912e-03	-5.54	Ig_sub2	interpro domains	IPR003598	239	4	18521	50	FGFR3,HEPACAM,NTM,LSAMP
3.936e-03	-5.54	rhabdomyosarcoma	COSMIC cancer mutations	rhabdomyosarcoma	4150	21	16828	49	ZNRF3,RORA,FGFR3,MAML2,RYR3,SPARCL1,GLIS3,NFIA,TRPS1,PARD3B,CLU,PAMR1,APOE,COL5A3,NPAS3,NHSL1,CDH20,PON2,PREX2,PTPRZ1,SLC1A3
3.979e-03	-5.53	glutamatergic synapse	cellular component	GO:0098978	412	5	19108	49	SPARCL1,TNIK,APOE,SLC1A2,GPM6A
4.006e-03	-5.52	inorganic cation transmembrane transporter activity	molecular function	GO:0022890	589	6	18094	47	ATP1A2,SLC1A2,SLC4A4,GPM6A,RYR3,SLC1A3
4.052e-03	-5.51	glial cell projection	cellular component	GO:0097386	37	2	19108	49	GLUL,SLC1A2
4.070e-03	-5.50	plasma membrane bounded cell projection	cellular component	GO:0120025	2285	13	19108	49	SLC1A2,CLU,GLUL,BMPR1B,APOE,PCDH9,ATP1A2,HEPACAM,CTNNA2,DTNA,GPM6A,SLC1A3,AHCYL2
4.071e-03	-5.50	TRNAU1AP (tRNA selenocysteine 1 associated protein 1)	protein interactions	54952	37	2	19454	50	ZBTB20,QKI
4.071e-03	-5.50	HPCA (hippocalcin)	protein interactions	3208	37	2	19454	50	CST3,GPM6A
4.127e-03	-5.49	striated muscle contraction	biological process	GO:0006941	120	3	18204	49	ATP1A2,RYR3,DTNA
4.221e-03	-5.47	PAS	smart domains	SM00091	25	2	9717	38	NPAS3,HIF3A
4.244e-03	-5.46	P_typ_ATPase_HD_dom	interpro domains	IPR044492	36	2	18521	50	ATP1A2,ATP13A4
4.244e-03	-5.46	P_typ_ATPase	interpro domains	IPR001757	36	2	18521	50	ATP13A4,ATP1A2
4.244e-03	-5.46	ATPase_P-typ_cyto_dom_N	interpro domains	IPR023299	36	2	18521	50	ATP13A4,ATP1A2
4.244e-03	-5.46	ATPase_P-typ_transduc_dom_A_sf	interpro domains	IPR008250	36	2	18521	50	ATP1A2,ATP13A4
4.244e-03	-5.46	ATPase_P-typ_P_site	interpro domains	IPR018303	36	2	18521	50	ATP13A4,ATP1A2
4.257e-03	-5.46	lung-right_lower_lobe-carcinoma-adenocarcinoma	COSMIC cancer mutations	lung-right_lower_lobe-carcinoma-adenocarcinoma	5692	26	16828	49	ATP13A4,ZNRF3,MAML2,NTM,TRPS1,PAMR1,LSAMP,AHCYL2,SLC4A4,PARD3B,ATP1A2,CLU,CDH20,SLC1A3,SOX5,HPSE2,RYR3,FBXL7,GPM6A,CST3,DTNA,GPC5,COL5A3,NKAIN3,NPAS3,PTPRZ1
4.257e-03	-5.46	right_lower_lobe	COSMIC cancer mutations	right_lower_lobe	5692	26	16828	49	MAML2,NTM,ZNRF3,ATP13A4,TRPS1,PARD3B,ATP1A2,CLU,AHCYL2,SLC4A4,LSAMP,PAMR1,SLC1A3,CDH20,SOX5,RYR3,HPSE2,GPC5,GPM6A,DTNA,CST3,FBXL7,COL5A3,PTPRZ1,NPAS3,NKAIN3
4.258e-03	-5.46	PAX9 (paired box 9)	protein interactions	5083	127	3	19454	50	TRPS1,QKI,NFIA
4.281e-03	-5.45	regulation of synapse organization	biological process	GO:0050807	246	4	18204	49	GPM6A,NRXN1,APOE,CTNNA2
4.290e-03	-5.45	Pcbp1 (poly(rC) binding protein 1)	protein interactions	23983	38	2	19454	50	QKI,MSI2
4.290e-03	-5.45	MMP3 (matrix metallopeptidase 3)	protein interactions	4314	38	2	19454	50	CLU,APOE
4.391e-03	-5.43	central_nervous_system-parietal_lobe-glioma-astrocytoma_Grade_I	COSMIC cancer mutations	central_nervous_system-parietal_lobe-glioma-astrocytoma_Grade_I	34	2	16828	49	FGFR3,QKI
4.432e-03	-5.42	L-glutamate and L-glutamine biosynthesis	BIOCYC pathways	META_PWY-5505	2	1	902	2	GLUL
4.451e-03	-5.41	positive regulation of nucleotide metabolic process	biological process	GO:0045981	37	2	18204	49	SLC4A4,ZBTB20
4.451e-03	-5.41	positive regulation of purine nucleotide metabolic process	biological process	GO:1900544	37	2	18204	49	ZBTB20,SLC4A4
4.478e-03	-5.41	ATPase_P-typ_TM_dom_sf	interpro domains	IPR023298	37	2	18521	50	ATP13A4,ATP1A2
4.493e-03	-5.41	protein-lipid complex	cellular component	GO:0032994	39	2	19108	49	APOE,CLU
4.602e-03	-5.38	FGFR1 (fibroblast growth factor receptor 1)	protein interactions	2260	611	6	19454	50	AHCYL2,CLU,FGFR3,NHSL1,DTNA,TNIK
4.662e-03	-5.37	regulation of synapse structure or activity	biological process	GO:0050803	252	4	18204	49	NRXN1,GPM6A,CTNNA2,APOE
4.691e-03	-5.36	amino acid import across plasma membrane	biological process	GO:0089718	38	2	18204	49	SLC1A2,SLC1A3
4.745e-03	-5.35	PAS	prosite domains	PS50112	30	2	12186	42	NPAS3,HIF3A
4.912e-03	-5.32	central_nervous_system-thalamus-glioma-astrocytoma_Grade_I	COSMIC cancer mutations	central_nervous_system-thalamus-glioma-astrocytoma_Grade_I	36	2	16828	49	FGFR3,QKI
4.918e-03	-5.31	cell differentiation	biological process	GO:0030154	3645	18	18204	49	SLC1A3,SOX5,FGFR3,NRXN1,NHSL1,CTNNA2,APOE,NFIA,MSI2,PREX2,NTM,GPM6A,TNIK,BMPR1B,RORA,PTPRZ1,QKI,CLU
4.936e-03	-5.31	sodium ion homeostasis	biological process	GO:0055078	39	2	18204	49	SLC1A3,ATP1A2
4.936e-03	-5.31	positive regulation of nitric oxide biosynthetic process	biological process	GO:0045429	39	2	18204	49	CLU,APOE
4.945e-03	-5.31	NUFIP1 (nuclear FMR1 interacting protein 1)	protein interactions	26747	134	3	19454	50	NTM,CPE,GPM6A
4.963e-03	-5.31	cellular developmental process	biological process	GO:0048869	3648	18	18204	49	NRXN1,FGFR3,CTNNA2,NHSL1,APOE,NFIA,SLC1A3,SOX5,CLU,MSI2,PREX2,NTM,TNIK,GPM6A,BMPR1B,RORA,PTPRZ1,QKI
4.977e-03	-5.30	striated_muscle	COSMIC cancer mutations	striated_muscle	4228	21	16828	49	SLC1A3,PTPRZ1,PREX2,CDH20,PON2,NPAS3,NHSL1,APOE,COL5A3,PAMR1,CLU,PARD3B,TRPS1,NFIA,GLIS3,SPARCL1,RYR3,MAML2,FGFR3,ZNRF3,RORA
5.029e-03	-5.29	anterograde trans-synaptic signaling	biological process	GO:0098916	415	5	18204	49	SLC1A2,APOE,DTNA,SLC1A3,NRXN1
5.029e-03	-5.29	chemical synaptic transmission	biological process	GO:0007268	415	5	18204	49	SLC1A3,DTNA,NRXN1,APOE,SLC1A2
5.122e-03	-5.27	discoidal high-density lipoprotein particle	cellular component	GO:0034365	2	1	19108	49	APOE
5.122e-03	-5.27	chylomicron remnant	cellular component	GO:0034360	2	1	19108	49	APOE
5.134e-03	-5.27	Irf7 (interferon regulatory factor 7)	protein interactions	54123	2	1	19454	50	BMPR1B
5.134e-03	-5.27	Bcr (BCR activator of RhoGEF and GTPase)	protein interactions	110279	2	1	19454	50	BMPR1B
5.134e-03	-5.27	Fbxo34 (F-box protein 34)	protein interactions	78938	2	1	19454	50	BMPR1B
5.134e-03	-5.27	Fkbp1b (FK506 binding protein 1b)	protein interactions	14226	2	1	19454	50	BMPR1B
5.134e-03	-5.27	Bmpr2 (bone morphogenetic protein receptor type 2)	protein interactions	12168	2	1	19454	50	BMPR1B
5.134e-03	-5.27	Sh3kbp1 (SH3-domain kinase binding protein 1)	protein interactions	58194	2	1	19454	50	BMPR1B
5.134e-03	-5.27	Ppp3cc (protein phosphatase 3, catalytic subunit, gamma isoform)	protein interactions	19057	2	1	19454	50	BMPR1B
5.134e-03	-5.27	Fkbp1a (FK506 binding protein 1a)	protein interactions	14225	2	1	19454	50	BMPR1B
5.134e-03	-5.27	Klhl1 (kelch-like 1)	protein interactions	93688	2	1	19454	50	BMPR1B
5.134e-03	-5.27	Zmym2 (zinc finger, MYM-type 2)	protein interactions	76007	2	1	19454	50	GLIS3
5.134e-03	-5.27	Kdm4c (lysine (K)-specific demethylase 4C)	protein interactions	76804	2	1	19454	50	GLIS3
5.134e-03	-5.27	Mknk2 (MAP kinase-interacting serine/threonine kinase 2)	protein interactions	17347	2	1	19454	50	BMPR1B
5.184e-03	-5.26	central_nervous_system-third_ventricle-glioma-astrocytoma_Grade_I	COSMIC cancer mutations	central_nervous_system-third_ventricle-glioma-astrocytoma_Grade_I	37	2	16828	49	QKI,FGFR3
5.187e-03	-5.26	positive regulation of nitric oxide metabolic process	biological process	GO:1904407	40	2	18204	49	CLU,APOE
5.188e-03	-5.26	ammonia ligase activity	molecular function	GO:0016211	2	1	18094	47	GLUL
5.188e-03	-5.26	glutamine synthetase activity	molecular function	GO:0004356	2	1	18094	47	GLUL
5.188e-03	-5.26	heparanase activity	molecular function	GO:0030305	2	1	18094	47	HPSE2
5.251e-03	-5.25	oligoastrocytoma_Grade_II	COSMIC cancer mutations	oligoastrocytoma_Grade_II	121	3	16828	49	DTNA,FGFR3,CDH20
5.322e-03	-5.24	neutral L-amino acid transmembrane transporter activity	molecular function	GO:0015175	42	2	18094	47	SLC1A3,SLC1A2
5.331e-03	-5.23	Calcium-transporting ATPase, cytoplasmic domain N	gene3d domains	3.40.1110.10	36	2	14470	44	ATP13A4,ATP1A2
5.331e-03	-5.23	Calcium-transporting ATPase, cytoplasmic transduction domain A	gene3d domains	2.70.150.10	36	2	14470	44	ATP1A2,ATP13A4
5.366e-03	-5.23	NFIB (nuclear factor I B)	protein interactions	4781	138	3	19454	50	NFIA,SOX5,TRPS1
5.376e-03	-5.23	glutamine biosynthetic process	biological process	GO:0006542	2	1	18204	49	GLUL
5.376e-03	-5.23	fibroblast growth factor receptor apoptotic signaling pathway	biological process	GO:1902178	2	1	18204	49	FGFR3
5.376e-03	-5.23	negative regulation of blood vessel remodeling	biological process	GO:0060313	2	1	18204	49	CST3
5.376e-03	-5.23	regulation of neurofibrillary tangle assembly	biological process	GO:1902996	2	1	18204	49	CLU
5.376e-03	-5.23	Wnt receptor catabolic process	biological process	GO:0038018	2	1	18204	49	ZNRF3
5.376e-03	-5.23	negative regulation of 3'-UTR-mediated mRNA stabilization	biological process	GO:1905869	2	1	18204	49	QKI
5.376e-03	-5.23	regulation of elastin catabolic process	biological process	GO:0060310	2	1	18204	49	CST3
5.376e-03	-5.23	lipid transport involved in lipid storage	biological process	GO:0010877	2	1	18204	49	APOE
5.376e-03	-5.23	myofibroblast contraction	biological process	GO:1990764	2	1	18204	49	QKI
5.377e-03	-5.23	somatodendritic compartment	cellular component	GO:0036477	842	7	19108	49	NRXN1,BMPR1B,SLC1A3,GPM6A,CLU,ATP1A2,APOE
5.386e-03	-5.22	membrane	cellular component	GO:0016020	9220	33	19108	49	PON2,BMPR1B,GLUL,ATP13A4,HPSE2,CLU,SLC1A2,HEPACAM,ATP1A2,CST3,SLC1A3,NTM,PARD3B,PTPRZ1,FGFR3,LSAMP,RYR3,NKAIN3,SLC4A4,HIF3A,CPE,TNIK,APOE,PCDH9,NRXN1,CTNNA2,GPM6A,DTNA,GPC5,PREX2,ZNRF3,PTGDS,CDH20
5.392e-03	-5.22	Clusterin-like	interpro domains	IPR000753	2	1	18521	50	CLU
5.392e-03	-5.22	Gln_synth_cat_dom	interpro domains	IPR008146	2	1	18521	50	GLUL
5.392e-03	-5.22	Glyco_hydro_79	interpro domains	IPR005199	2	1	18521	50	HPSE2
5.392e-03	-5.22	Gln_synt_N	interpro domains	IPR008147	2	1	18521	50	GLUL
5.392e-03	-5.22	Gln_synt_N_sf	interpro domains	IPR036651	2	1	18521	50	GLUL
5.392e-03	-5.22	Clusterin_C	interpro domains	IPR016015	2	1	18521	50	CLU
5.392e-03	-5.22	ZNRF-3_ecto	interpro domains	IPR040700	2	1	18521	50	ZNRF3
5.392e-03	-5.22	Par3/HAL_N	interpro domains	IPR021922	2	1	18521	50	PARD3B
5.392e-03	-5.22	MSI_RRM2	interpro domains	IPR034126	2	1	18521	50	MSI2
5.392e-03	-5.22	Paraoxonase2	interpro domains	IPR008364	2	1	18521	50	PON2
5.392e-03	-5.22	Osteonectin_CS	interpro domains	IPR001999	2	1	18521	50	SPARCL1
5.392e-03	-5.22	Distrobrevin	interpro domains	IPR017432	2	1	18521	50	DTNA
5.392e-03	-5.22	Alpha_CARP_receptor-type	interpro domains	IPR041887	2	1	18521	50	PTPRZ1
5.392e-03	-5.22	Clusterin_N	interpro domains	IPR016014	2	1	18521	50	CLU
5.432e-03	-5.22	Ig_I-set	interpro domains	IPR013098	132	3	18521	50	NTM,LSAMP,FGFR3
5.440e-03	-5.21	monoatomic ion transmembrane transport	biological process	GO:0034220	804	7	18204	49	SLC1A2,SLC1A3,GPM6A,ATP1A2,SLC4A4,RYR3,ATP13A4
5.461e-03	-5.21	central_nervous_system-brainstem-glioma-astrocytoma_Grade_I	COSMIC cancer mutations	central_nervous_system-brainstem-glioma-astrocytoma_Grade_I	38	2	16828	49	QKI,FGFR3
5.517e-03	-5.20	Glutamatergic synapse	KEGG pathways	hsa04724	114	3	7161	23	SLC1A2,GLUL,SLC1A3
5.517e-03	-5.20	Glutamatergic synapse	KEGG pathways	ko04724	114	3	7161	23	SLC1A2,GLUL,SLC1A3
5.572e-03	-5.19	tau protein binding	molecular function	GO:0048156	43	2	18094	47	APOE,CLU
5.612e-03	-5.18	Gln-synt_C	pfam domains	PF00120	2	1	17795	50	GLUL
5.612e-03	-5.18	Glyco_hydro_79n	pfam domains	PF03662	2	1	17795	50	HPSE2
5.612e-03	-5.18	Par3_HAL_N_term	pfam domains	PF12053	2	1	17795	50	PARD3B
5.612e-03	-5.18	ZNRF_3_ecto	pfam domains	PF18212	2	1	17795	50	ZNRF3
5.612e-03	-5.18	Clusterin	pfam domains	PF01093	2	1	17795	50	CLU
5.696e-03	-5.17	UPK2 (uroplakin 2)	protein interactions	7379	141	3	19454	50	PCDH9,PON2,CTNNA2
5.706e-03	-5.17	triglyceride homeostasis	biological process	GO:0070328	42	2	18204	49	RORA,APOE
5.718e-03	-5.16	active transmembrane transporter activity	molecular function	GO:0022804	444	5	18094	47	SLC1A2,SLC4A4,ATP13A4,ATP1A2,SLC1A3
5.767e-03	-5.16	sarcolemma	cellular component	GO:0042383	142	3	19108	49	ATP1A2,DTNA,RYR3
5.890e-03	-5.13	trans-synaptic signaling	biological process	GO:0099537	431	5	18204	49	APOE,SLC1A2,NRXN1,SLC1A3,DTNA
5.974e-03	-5.12	acylglycerol homeostasis	biological process	GO:0055090	43	2	18204	49	RORA,APOE
6.004e-03	-5.12	inorganic ion homeostasis	biological process	GO:0098771	433	5	18204	49	RYR3,SLC1A3,ATP13A4,APOE,ATP1A2
6.018e-03	-5.11	carboxylic acid biosynthetic process	biological process	GO:0046394	271	4	18204	49	SLC1A3,GLUL,PTGDS,QKI
6.064e-03	-5.11	I-set	pfam domains	PF07679	132	3	17795	50	NTM,LSAMP,FGFR3
6.073e-03	-5.10	Vinculin, Vh2 four-helix bundle	gene3d domains	1.20.120.810	2	1	14470	44	CTNNA2
6.073e-03	-5.10	-	gene3d domains	6.20.350.10	2	1	14470	44	RYR3
6.073e-03	-5.10	Glutamine synthetase, N-terminal domain	gene3d domains	3.10.20.70	2	1	14470	44	GLUL
6.107e-03	-5.10	axon	cellular component	GO:0030424	650	6	19108	49	CTNNA2,SLC1A2,GPM6A,DTNA,PCDH9,HEPACAM
6.121e-03	-5.10	blood vessel morphogenesis	biological process	GO:0048514	435	5	18204	49	GLUL,QKI,APOE,RORA,HIF3A
6.127e-03	-5.10	cell-cell signaling	biological process	GO:0007267	822	7	18204	49	APOE,SLC1A2,FGFR3,NRXN1,SLC1A3,CPE,DTNA
6.254e-03	-5.07	organic acid biosynthetic process	biological process	GO:0016053	274	4	18204	49	PTGDS,SLC1A3,GLUL,QKI
6.334e-03	-5.06	gliogenesis	biological process	GO:0042063	275	4	18204	49	CLU,NFIA,PTPRZ1,QKI
6.414e-03	-5.05	learning or memory	biological process	GO:0007611	276	4	18204	49	PTPRZ1,APOE,ATP1A2,NRXN1
6.454e-03	-5.04	leg	COSMIC cancer mutations	leg	969	8	16828	49	PTPRZ1,ZBTB20,HIF3A,SLC4A4,FGFR3,ATP13A4,NTM,COL5A3
6.500e-03	-5.04	CNTN1 (contactin 1)	protein interactions	1272	47	2	19454	50	GPM6A,PTPRZ1
6.527e-03	-5.03	acidic amino acid transport	biological process	GO:0015800	45	2	18204	49	SLC1A2,SLC1A3
6.550e-03	-5.03	PAS domain	gene3d domains	3.30.450.20	40	2	14470	44	NPAS3,HIF3A
6.588e-03	-5.02	monoatomic anion transmembrane transport	biological process	GO:0098656	142	3	18204	49	SLC1A3,SLC1A2,SLC4A4
6.588e-03	-5.02	positive regulation of small molecule metabolic process	biological process	GO:0062013	142	3	18204	49	ZBTB20,SLC4A4,APOE
6.634e-03	-5.02	GSE1 (Gse1 coiled-coil protein)	protein interactions	23199	149	3	19454	50	SOX5,TNIK,NFIA
6.645e-03	-5.01	GABA shunt	BIOCYC pathways	HUMAN_GLUDEG-I-PWY	3	1	902	2	GLUL
6.684e-03	-5.01	symporter activity	molecular function	GO:0015293	148	3	18094	47	SLC1A3,SLC1A2,SLC4A4
6.783e-03	-4.99	ATPASE_E1_E2	prosite domains	PS00154	36	2	12186	42	ATP1A2,ATP13A4
6.812e-03	-4.99	receptor clustering	biological process	GO:0043113	46	2	18204	49	APOE,NRXN1
6.812e-03	-4.99	regulation of oligodendrocyte differentiation	biological process	GO:0048713	46	2	18204	49	QKI,PTPRZ1
6.812e-03	-4.99	positive regulation of glial cell differentiation	biological process	GO:0045687	46	2	18204	49	PTPRZ1,QKI
6.882e-03	-4.98	GS_CATALYTIC	prosite domains	PS51987	2	1	12186	42	GLUL
6.882e-03	-4.98	OSTEONECTIN_2	prosite domains	PS00613	2	1	12186	42	SPARCL1
6.882e-03	-4.98	OSTEONECTIN_1	prosite domains	PS00612	2	1	12186	42	SPARCL1
6.882e-03	-4.98	GS_BETA_GRASP	prosite domains	PS51986	2	1	12186	42	GLUL
6.928e-03	-4.97	monoatomic cation transmembrane transport	biological process	GO:0098655	636	6	18204	49	ATP13A4,SLC1A3,RYR3,GPM6A,SLC4A4,ATP1A2
6.932e-03	-4.97	soft_tissue-striated_muscle-rhabdomyosarcoma-embryonal	COSMIC cancer mutations	soft_tissue-striated_muscle-rhabdomyosarcoma-embryonal	2659	15	16828	49	RORA,ZNRF3,FGFR3,MAML2,RYR3,SPARCL1,GLIS3,NFIA,PARD3B,COL5A3,APOE,NPAS3,PON2,PTPRZ1,PREX2
6.932e-03	-4.97	embryonal	COSMIC cancer mutations	embryonal	2659	15	16828	49	SPARCL1,FGFR3,ZNRF3,RORA,RYR3,MAML2,NFIA,GLIS3,APOE,COL5A3,PARD3B,PON2,NPAS3,PREX2,PTPRZ1
7.064e-03	-4.95	SP7 (Sp7 transcription factor)	protein interactions	121340	297	4	19454	50	NFIA,TRPS1,QKI,SOX5
7.135e-03	-4.94	SOX6 (SRY-box transcription factor 6)	protein interactions	55553	153	3	19454	50	TRPS1,SOX5,NFIA
7.399e-03	-4.91	regulation of amyloid-beta formation	biological process	GO:1902003	48	2	18204	49	CLU,APOE
7.404e-03	-4.91	large_intestine-adenoma	COSMIC cancer mutations	large_intestine-adenoma	266	4	16828	49	APOE,CDH20,RYR3,SOX5
7.519e-03	-4.89	neuromuscular process	biological process	GO:0050905	149	3	18204	49	CTNNA2,SLC1A3,NRXN1
7.592e-03	-4.88	third_ventricle	COSMIC cancer mutations	third_ventricle	45	2	16828	49	QKI,FGFR3
7.617e-03	-4.88	LINGO1 (leucine rich repeat and Ig domain containing 1)	protein interactions	84894	51	2	19454	50	NTM,PON2
7.631e-03	-4.88	human chr8q23.3	chromosome location	human chr8q23.3	4	1	26134	50	TRPS1
7.639e-03	-4.87	PARAOXONASE2	prints domains	PR01787	2	1	5227	20	PON2
7.640e-03	-4.87	synaptic signaling	biological process	GO:0099536	459	5	18204	49	APOE,SLC1A2,NRXN1,SLC1A3,DTNA
7.674e-03	-4.87	CATATPASE	prints domains	PR00119	35	2	5227	20	ATP13A4,ATP1A2
7.688e-03	-4.87	Retinoid metabolism and transport	REACTOME pathways	R-HSA-975634	44	2	10285	31	APOE,GPC5
7.691e-03	-4.87	Smad6 (SMAD family member 6)	protein interactions	17130	3	1	19454	50	BMPR1B
7.691e-03	-4.87	Chn1 (chimerin 1)	protein interactions	108699	3	1	19454	50	BMPR1B
7.691e-03	-4.87	Spop (speckle-type BTB/POZ protein)	protein interactions	20747	3	1	19454	50	GLIS3
7.691e-03	-4.87	Fbxw5 (F-box and WD-40 domain protein 5)	protein interactions	30839	3	1	19454	50	BMPR1B
7.691e-03	-4.87	Plekhb1 (pleckstrin homology domain containing, family B (evectins) member 1)	protein interactions	27276	3	1	19454	50	BMPR1B
7.691e-03	-4.87	TULP1 (TUB like protein 1)	protein interactions	7287	3	1	19454	50	NRXN1
7.691e-03	-4.87	Stk35 (serine/threonine kinase 35)	protein interactions	67333	3	1	19454	50	BMPR1B
7.691e-03	-4.87	QRFPR (pyroglutamylated RFamide peptide receptor)	protein interactions	84109	3	1	19454	50	NTM
7.691e-03	-4.87	Rap2a (RAS related protein 2a)	protein interactions	76108	3	1	19454	50	BMPR1B
7.691e-03	-4.87	Atg16l1 (autophagy related 16 like 1)	protein interactions	77040	3	1	19454	50	BMPR1B
7.691e-03	-4.87	IL34 (interleukin 34)	protein interactions	146433	3	1	19454	50	PTPRZ1
7.691e-03	-4.87	Usp45 (ubiquitin specific petidase 45)	protein interactions	77593	3	1	19454	50	BMPR1B
7.691e-03	-4.87	Lep (leptin)	protein interactions	16846	3	1	19454	50	CLU
7.691e-03	-4.87	Hk2 (hexokinase 2)	protein interactions	25059	3	1	19454	50	PTGDS
7.700e-03	-4.87	astrocytoma_Grade_I	COSMIC cancer mutations	astrocytoma_Grade_I	139	3	16828	49	QKI,FGFR3,GPC5
7.762e-03	-4.86	anchoring junction	cellular component	GO:0070161	902	7	19108	49	FGFR3,CTNNA2,HEPACAM,PARD3B,ATP1A2,PCDH9,CDH20
7.773e-03	-4.86	prostaglandin-D synthase activity	molecular function	GO:0004667	3	1	18094	47	PTGDS
7.773e-03	-4.86	hydrolase activity, acting on carbon-sulfur bonds	molecular function	GO:0046508	3	1	18094	47	AHCYL2
7.773e-03	-4.86	adenosylhomocysteinase activity	molecular function	GO:0004013	3	1	18094	47	AHCYL2
7.773e-03	-4.86	acid-ammonia (or amide) ligase activity	molecular function	GO:0016880	3	1	18094	47	GLUL
7.773e-03	-4.86	acyl-L-homoserine-lactone lactonohydrolase activity	molecular function	GO:0102007	3	1	18094	47	PON2
7.773e-03	-4.86	lactonohydrolase activity	molecular function	GO:0046573	3	1	18094	47	PON2
7.773e-03	-4.86	cysteine transmembrane transporter activity	molecular function	GO:0033229	3	1	18094	47	SLC1A2
7.806e-03	-4.85	CLb	smart domains	SM00030	2	1	9717	38	CLU
7.806e-03	-4.85	CLa	smart domains	SM00035	2	1	9717	38	CLU
7.806e-03	-4.85	Gln-synt_C	smart domains	SM01230	2	1	9717	38	GLUL
7.928e-03	-4.84	TYRO3 (TYRO3 protein tyrosine kinase)	protein interactions	7301	159	3	19454	50	SLC1A3,APOE,CLU
7.942e-03	-4.84	pancreas-carcinoid-endocrine_tumour	COSMIC cancer mutations	pancreas-carcinoid-endocrine_tumour	7250	30	16828	49	CDH20,NHSL1,SLC1A3,PREX2,APOE,CPE,PAMR1,LSAMP,AHCYL2,SLC4A4,CLU,ATP1A2,GLIS3,FGFR3,PCDH9,ATP13A4,MAML2,NKAIN3,PON2,SLC1A2,COL5A3,BMPR1B,FBXL7,GPM6A,GPC5,QKI,RORA,HPSE2,RYR3,SOX5
7.987e-03	-4.83	cellular response to organic cyclic compound	biological process	GO:0071407	464	5	18204	49	ATP1A2,SLC1A2,RORA,SLC1A3,RYR3
8.054e-03	-4.82	regulation of calcium:sodium antiporter activity	biological process	GO:1903279	3	1	18204	49	ATP1A2
8.054e-03	-4.82	cysteine transmembrane transport	biological process	GO:1903712	3	1	18204	49	SLC1A2
8.054e-03	-4.82	immune complex clearance	biological process	GO:0002434	3	1	18204	49	CLU
8.054e-03	-4.82	cysteine transport	biological process	GO:0042883	3	1	18204	49	SLC1A2
8.054e-03	-4.82	neuroligin clustering involved in postsynaptic membrane assembly	biological process	GO:0097118	3	1	18204	49	NRXN1
8.054e-03	-4.82	radial glia guided migration of Purkinje cell	biological process	GO:0021942	3	1	18204	49	CTNNA2
8.054e-03	-4.82	very-low-density lipoprotein particle clearance	biological process	GO:0034447	3	1	18204	49	APOE
8.054e-03	-4.82	protein targeting to lysosome involved in chaperone-mediated autophagy	biological process	GO:0061740	3	1	18204	49	CLU
8.054e-03	-4.82	positive regulation of low-density lipoprotein particle receptor catabolic process	biological process	GO:0032805	3	1	18204	49	APOE
8.065e-03	-4.82	SOX5 (SRY-box transcription factor 5)	protein interactions	6660	160	3	19454	50	NFIA,SOX5,TRPS1
8.078e-03	-4.82	S-Ado-L-homoCys_hydrolase_CS	interpro domains	IPR020082	3	1	18521	50	AHCYL2
8.078e-03	-4.82	Ado_hCys_hydrolase_NAD-bd	interpro domains	IPR015878	3	1	18521	50	AHCYL2
8.078e-03	-4.82	Arylesterase	interpro domains	IPR002640	3	1	18521	50	PON2
8.078e-03	-4.82	Adenosylhomocysteinase-like	interpro domains	IPR000043	3	1	18521	50	AHCYL2
8.078e-03	-4.82	MAML_N_sf	interpro domains	IPR046370	3	1	18521	50	MAML2
8.078e-03	-4.82	Myelin_PLP	interpro domains	IPR001614	3	1	18521	50	GPM6A
8.078e-03	-4.82	NR_DBD_ROR	interpro domains	IPR044101	3	1	18521	50	RORA
8.078e-03	-4.82	SPRY2_RyR	interpro domains	IPR035764	3	1	18521	50	RYR3
8.078e-03	-4.82	Mastermind-like_N	interpro domains	IPR019082	3	1	18521	50	MAML2
8.078e-03	-4.82	Ryanodine_rcpt	interpro domains	IPR003032	3	1	18521	50	RYR3
8.078e-03	-4.82	RYDR_Jsol	interpro domains	IPR048581	3	1	18521	50	RYR3
8.078e-03	-4.82	Ryanrecept_TM4-6	interpro domains	IPR009460	3	1	18521	50	RYR3
8.078e-03	-4.82	HIF_alpha-like	interpro domains	IPR021537	3	1	18521	50	HIF3A
8.078e-03	-4.82	MAML1-3	interpro domains	IPR046369	3	1	18521	50	MAML2
8.078e-03	-4.82	Ryan_recept	interpro domains	IPR013333	3	1	18521	50	RYR3
8.078e-03	-4.82	SPRY3_RyR	interpro domains	IPR035762	3	1	18521	50	RYR3
8.078e-03	-4.82	Adenosylhomocyst_ase-like_sf	interpro domains	IPR042172	3	1	18521	50	AHCYL2
8.078e-03	-4.82	SPRY1_RyR	interpro domains	IPR035761	3	1	18521	50	RYR3
8.078e-03	-4.82	Myelin_PLP_CS	interpro domains	IPR018237	3	1	18521	50	GPM6A
8.078e-03	-4.82	ROR_rcpt	interpro domains	IPR003079	3	1	18521	50	RORA
8.078e-03	-4.82	Vinculin_CS	interpro domains	IPR000633	3	1	18521	50	CTNNA2
8.157e-03	-4.81	oesophagus-middle_third-carcinoma-squamous_cell_carcinoma	COSMIC cancer mutations	oesophagus-middle_third-carcinoma-squamous_cell_carcinoma	3531	18	16828	49	ZBTB20,GPC5,GPM6A,SPARCL1,SOX5,MAML2,TNIK,RYR3,HPSE2,PCDH9,PTPRZ1,PREX2,NHSL1,PON2,PAMR1,COL5A3,ATP1A2,SLC4A4
8.206e-03	-4.80	FOXF2 (forkhead box F2)	protein interactions	2295	53	2	19454	50	ZBTB20,AHCYL2
8.206e-03	-4.80	middle_third	COSMIC cancer mutations	middle_third	3533	18	16828	49	SLC4A4,ATP1A2,COL5A3,PAMR1,PON2,NHSL1,PREX2,PTPRZ1,PCDH9,TNIK,RYR3,HPSE2,SOX5,MAML2,SPARCL1,GPM6A,GPC5,ZBTB20
8.320e-03	-4.79	neuromuscular process controlling balance	biological process	GO:0050885	51	2	18204	49	NRXN1,SLC1A3
8.365e-03	-4.78	ATPase-coupled monoatomic cation transmembrane transporter activity	molecular function	GO:0019829	53	2	18094	47	ATP13A4,ATP1A2
8.406e-03	-4.78	MamL-1	pfam domains	PF09596	3	1	17795	50	MAML2
8.406e-03	-4.78	Arylesterase	pfam domains	PF01731	3	1	17795	50	PON2
8.406e-03	-4.78	AdoHcyase_NAD	pfam domains	PF00670	3	1	17795	50	AHCYL2
8.406e-03	-4.78	AdoHcyase	pfam domains	PF05221	3	1	17795	50	AHCYL2
8.406e-03	-4.78	Myelin_PLP	pfam domains	PF01275	3	1	17795	50	GPM6A
8.406e-03	-4.78	HIF-1	pfam domains	PF11413	3	1	17795	50	HIF3A
8.406e-03	-4.78	RyR	pfam domains	PF02026	3	1	17795	50	RYR3
8.406e-03	-4.78	RR_TM4-6	pfam domains	PF06459	3	1	17795	50	RYR3
8.406e-03	-4.78	RYDR_Jsol	pfam domains	PF21119	3	1	17795	50	RYR3
8.447e-03	-4.77	ion binding	molecular function	GO:0043167	6007	24	18094	47	TNIK,ZBTB20,ATP13A4,BMPR1B,PON2,SLC1A3,FGFR3,ATP1A2,ZNRF3,GLIS3,CPE,PCDH9,PAMR1,PTGDS,PITPNC1,TRPS1,RORA,RYR3,SLC1A2,APOE,SPARCL1,NRXN1,DTNA,GLUL
8.525e-03	-4.76	retina development in camera-type eye	biological process	GO:0060041	156	3	18204	49	BMPR1B,NFIA,GPM6A
8.613e-03	-4.75	thyroid-carcinoma	COSMIC cancer mutations	thyroid-carcinoma	4126	20	16828	49	SPARCL1,TNIK,RYR3,SOX5,PCDH9,FGFR3,ZNRF3,ATP13A4,HIF3A,TRPS1,NFIA,GPC5,NRXN1,DTNA,GLIS3,LSAMP,COL5A3,CPE,ATP1A2,PTPRZ1
8.638e-03	-4.75	regulation of purine nucleotide catabolic process	biological process	GO:0033121	52	2	18204	49	ZBTB20,SLC4A4
8.638e-03	-4.75	regulation of glycolytic process	biological process	GO:0006110	52	2	18204	49	ZBTB20,SLC4A4
8.638e-03	-4.75	regulation of nucleotide catabolic process	biological process	GO:0030811	52	2	18204	49	SLC4A4,ZBTB20
8.711e-03	-4.74	skin-hand-lentigo	COSMIC cancer mutations	skin-hand-lentigo	3	1	16828	49	FGFR3
8.711e-03	-4.74	skin-lentigo	COSMIC cancer mutations	skin-lentigo	3	1	16828	49	FGFR3
8.711e-03	-4.74	lentigo	COSMIC cancer mutations	lentigo	3	1	16828	49	FGFR3
8.711e-03	-4.74	skin-trunk-other-seborrhoeic_keratosis	COSMIC cancer mutations	skin-trunk-other-seborrhoeic_keratosis	3	1	16828	49	FGFR3
8.711e-03	-4.74	urinary_tract-bladder-papilloma	COSMIC cancer mutations	urinary_tract-bladder-papilloma	3	1	16828	49	FGFR3
8.711e-03	-4.74	skin-trunk-lentigo	COSMIC cancer mutations	skin-trunk-lentigo	3	1	16828	49	FGFR3
8.711e-03	-4.74	skin-forearm-lentigo	COSMIC cancer mutations	skin-forearm-lentigo	3	1	16828	49	FGFR3
8.711e-03	-4.74	skin-face-lentigo	COSMIC cancer mutations	skin-face-lentigo	3	1	16828	49	FGFR3
8.711e-03	-4.74	skin-leg-lentigo	COSMIC cancer mutations	skin-leg-lentigo	3	1	16828	49	FGFR3
8.711e-03	-4.74	skin-leg-other-seborrhoeic_keratosis	COSMIC cancer mutations	skin-leg-other-seborrhoeic_keratosis	3	1	16828	49	FGFR3
8.736e-03	-4.74	Amyotrophic lateral sclerosis (ALS)	WikiPathways	WP2447	38	2	5310	20	CST3,SLC1A2
8.771e-03	-4.74	EGR2 (early growth response 2)	protein interactions	1959	165	3	19454	50	SOX5,TRPS1,NFIA
8.814e-03	-4.73	AMPH (amphiphysin)	protein interactions	273	55	2	19454	50	GLUL,GPM6A
8.962e-03	-4.71	neutral amino acid transport	biological process	GO:0015804	53	2	18204	49	SLC1A2,SLC1A3
8.979e-03	-4.71	monoatomic anion transport	biological process	GO:0006820	159	3	18204	49	SLC1A2,SLC4A4,SLC1A3
9.061e-03	-4.70	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm	7307	30	16828	49	PAMR1,CPE,LSAMP,AHCYL2,CLU,PARD3B,CDH20,NHSL1,SLC1A3,PREX2,PCDH9,ATP13A4,MAML2,GLIS3,COL5A3,BMPR1B,NKAIN3,SLC1A2,PON2,PTPRZ1,QKI,SPARCL1,RORA,TNIK,HPSE2,RYR3,SOX5,FBXL7,GPM6A,GPC5
9.095e-03	-4.70	-	gene3d domains	1.10.490.160	3	1	14470	44	RYR3
9.095e-03	-4.70	-	gene3d domains	6.10.250.970	3	1	14470	44	MAML2
9.095e-03	-4.70	-	gene3d domains	6.10.250.2510	3	1	14470	44	CTNNA2
9.095e-03	-4.70	Adenosylhomocysteinase-like	gene3d domains	3.40.50.1480	3	1	14470	44	AHCYL2
9.147e-03	-4.69	presynaptic membrane	cellular component	GO:0042734	168	3	19108	49	NRXN1,SLC1A2,GPM6A
9.290e-03	-4.68	negative regulation of supramolecular fiber organization	biological process	GO:1902904	161	3	18204	49	APOE,CTNNA2,CLU
9.302e-03	-4.68	lipid transfer activity	molecular function	GO:0120013	56	2	18094	47	PITPNC1,APOE
9.442e-03	-4.66	NXPH3 (neurexophilin 3)	protein interactions	11248	57	2	19454	50	NRXN1,CTNNA2
9.565e-03	-4.65	export from cell	biological process	GO:0140352	485	5	18204	49	CPE,NRXN1,PTGDS,SLC4A4,ATP1A2
9.616e-03	-4.64	lung-carcinoma-squamous_cell_carcinoma	COSMIC cancer mutations	lung-carcinoma-squamous_cell_carcinoma	14664	48	16828	49	SLC1A3,PREX2,PARD3B,APOE,CPE,NRXN1,GLIS3,MAML2,PCDH9,ZNRF3,PTGDS,PTPRZ1,SLC1A2,NPAS3,NKAIN3,GLUL,BMPR1B,GPC5,ZBTB20,GPM6A,NFIA,HPSE2,TNIK,RYR3,RORA,QKI,CDH20,NHSL1,PITPNC1,CLU,ATP1A2,SLC4A4,AHCYL2,LSAMP,PAMR1,HIF3A,HEPACAM,TRPS1,NTM,FGFR3,ATP13A4,PON2,COL5A3,MSI2,DTNA,FBXL7,SOX5,SPARCL1
9.625e-03	-4.64	intermembrane lipid transfer	biological process	GO:0120009	55	2	18204	49	APOE,PITPNC1
9.625e-03	-4.64	response to cocaine	biological process	GO:0042220	55	2	18204	49	SLC1A3,SLC1A2
9.625e-03	-4.64	regulation of amyloid precursor protein catabolic process	biological process	GO:1902991	55	2	18204	49	CLU,APOE
9.630e-03	-4.64	CTNNA1 (catenin alpha 1)	protein interactions	1495	325	4	19454	50	DTNA,TNIK,CTNNA2,NHSL1
9.634e-03	-4.64	biliary_tract	COSMIC cancer mutations	biliary_tract	15309	49	16828	49	CDH20,NHSL1,PITPNC1,CLU,ATP1A2,AHCYL2,SLC4A4,LSAMP,PAMR1,HIF3A,TRPS1,HEPACAM,NTM,FGFR3,ATP13A4,PON2,COL5A3,MSI2,DTNA,CST3,FBXL7,SOX5,SPARCL1,PREX2,SLC1A3,PARD3B,APOE,CPE,NRXN1,GLIS3,MAML2,PCDH9,ZNRF3,PTGDS,PTPRZ1,SLC1A2,NPAS3,NKAIN3,GLUL,BMPR1B,GPC5,ZBTB20,GPM6A,NFIA,RYR3,HPSE2,TNIK,RORA,QKI
9.709e-03	-4.63	HNRNPL (heterogeneous nuclear ribonucleoprotein L)	protein interactions	3191	1958	11	19454	50	BMPR1B,PARD3B,FGFR3,AHCYL2,NFIA,MSI2,ZBTB20,DTNA,QKI,TRPS1,PON2
9.763e-03	-4.63	HOXB6 (homeobox B6)	protein interactions	3216	58	2	19454	50	AHCYL2,GLUL
9.818e-03	-4.62	plasma_cell_myeloma	COSMIC cancer mutations	plasma_cell_myeloma	1263	9	16828	49	GPM6A,TRPS1,HPSE2,RYR3,TNIK,NTM,FGFR3,ATP13A4,PAMR1
9.818e-03	-4.62	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-plasma_cell_myeloma	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-plasma_cell_myeloma	1263	9	16828	49	GPM6A,TRPS1,HPSE2,TNIK,RYR3,NTM,FGFR3,ATP13A4,PAMR1
9.929e-03	-4.61	import across plasma membrane	biological process	GO:0098739	165	3	18204	49	SLC1A3,ATP1A2,SLC1A2
1.001e-02	-4.60	inorganic molecular entity transmembrane transporter activity	molecular function	GO:0015318	714	6	18094	47	SLC1A3,RYR3,SLC4A4,SLC1A2,GPM6A,ATP1A2
1.002e-02	-4.60	Znf_NHR/GATA	interpro domains	IPR013088	56	2	18521	50	TRPS1,RORA
1.009e-02	-4.60	VEGFA (vascular endothelial growth factor A)	protein interactions	7422	59	2	19454	50	PTPRZ1,CLU
1.022e-02	-4.58	extrinsic component of membrane	cellular component	GO:0019898	175	3	19108	49	CTNNA2,CDH20,DTNA
1.022e-02	-4.58	collagen type V trimer	cellular component	GO:0005588	4	1	19108	49	COL5A3
1.022e-02	-4.58	intermediate-density lipoprotein particle	cellular component	GO:0034363	4	1	19108	49	APOE
1.023e-02	-4.58	Neurotransmitter Release Cycle	REACTOME pathways	R-HSA-112310	51	2	10285	31	SLC1A2,SLC1A3
1.024e-02	-4.58	Nkiras1 (NFKB inhibitor interacting Ras-like protein 1)	protein interactions	69721	4	1	19454	50	BMPR1B
1.024e-02	-4.58	Ctbp2 (C-terminal binding protein 2)	protein interactions	13017	4	1	19454	50	TRPS1
1.024e-02	-4.58	Srgap1 (SLIT-ROBO Rho GTPase activating protein 1)	protein interactions	117600	4	1	19454	50	BMPR1B
1.024e-02	-4.58	Naa20 (N(alpha)-acetyltransferase 20, NatB catalytic subunit)	protein interactions	67877	4	1	19454	50	BMPR1B
1.024e-02	-4.58	Dnaja1 (DnaJ heat shock protein family (Hsp40) member A1)	protein interactions	15502	4	1	19454	50	GLIS3
1.024e-02	-4.58	Arhgef6 (Rac/Cdc42 guanine nucleotide exchange factor 6)	protein interactions	73341	4	1	19454	50	BMPR1B
1.024e-02	-4.58	CCDC126 (coiled-coil domain containing 126)	protein interactions	90693	4	1	19454	50	GPM6A
1.024e-02	-4.58	Cdk14 (cyclin dependent kinase 14)	protein interactions	18647	4	1	19454	50	BMPR1B
1.024e-02	-4.58	Nme2 (NME/NM23 nucleoside diphosphate kinase 2)	protein interactions	18103	4	1	19454	50	RORA
1.024e-02	-4.58	Ilkap (integrin-linked kinase-associated serine/threonine phosphatase 2C)	protein interactions	67444	4	1	19454	50	BMPR1B
1.024e-02	-4.58	Rhebl1 (Ras homolog enriched in brain like 1)	protein interactions	69159	4	1	19454	50	BMPR1B
1.025e-02	-4.58	cellular response to endogenous stimulus	biological process	GO:0071495	1135	8	18204	49	ATP1A2,NFIA,RYR3,FGFR3,BMPR1B,SLC1A2,SLC1A3,SOX5
1.029e-02	-4.58	LHX3 (LIM homeobox 3)	protein interactions	8022	175	3	19454	50	SOX5,TRPS1,NFIA
1.030e-02	-4.58	MYELIN_PLP_1	prosite domains	PS00575	3	1	12186	42	GPM6A
1.030e-02	-4.58	VINCULIN_1	prosite domains	PS00663	3	1	12186	42	CTNNA2
1.030e-02	-4.58	ADOHCYASE_1	prosite domains	PS00738	3	1	12186	42	AHCYL2
1.030e-02	-4.58	MYELIN_PLP_2	prosite domains	PS01004	3	1	12186	42	GPM6A
1.030e-02	-4.58	ADOHCYASE_2	prosite domains	PS00739	3	1	12186	42	AHCYL2
1.031e-02	-4.57	visual behavior	biological process	GO:0007632	57	2	18204	49	SLC1A2,ATP1A2
1.032e-02	-4.57	SLC-mediated transmembrane transport	REACTOME pathways	R-HSA-425407	287	4	10285	31	SLC1A3,AHCYL2,SLC4A4,SLC1A2
1.035e-02	-4.57	very-low-density lipoprotein particle receptor binding	molecular function	GO:0070326	4	1	18094	47	APOE
1.035e-02	-4.57	ryanodine-sensitive calcium-release channel activity	molecular function	GO:0005219	4	1	18094	47	RYR3
1.042e-02	-4.56	ITGA8 (integrin subunit alpha 8)	protein interactions	8516	60	2	19454	50	ZNRF3,CLU
1.042e-02	-4.56	SNTB1 (syntrophin beta 1)	protein interactions	6641	60	2	19454	50	DTNA,FGFR3
1.055e-02	-4.55	cognition	biological process	GO:0050890	319	4	18204	49	APOE,PTPRZ1,ATP1A2,NRXN1
1.061e-02	-4.55	GATA3 (GATA binding protein 3)	protein interactions	2625	177	3	19454	50	NFIA,TRPS1,QKI
1.072e-02	-4.54	negative regulation of male germ cell proliferation	biological process	GO:2000255	4	1	18204	49	PTGDS
1.072e-02	-4.54	regulation of glutamate uptake involved in transmission of nerve impulse	biological process	GO:0051946	4	1	18204	49	ATP1A2
1.072e-02	-4.54	regulation of amino acid uptake involved in synaptic transmission	biological process	GO:0051941	4	1	18204	49	ATP1A2
1.072e-02	-4.54	response to glycoside	biological process	GO:1903416	4	1	18204	49	ATP1A2
1.072e-02	-4.54	NMDA glutamate receptor clustering	biological process	GO:0097114	4	1	18204	49	APOE
1.072e-02	-4.54	regulation of collagen catabolic process	biological process	GO:0010710	4	1	18204	49	CST3
1.072e-02	-4.54	positive regulation of inclusion body assembly	biological process	GO:0090261	4	1	18204	49	CLU
1.072e-02	-4.54	protein localization to secretory granule	biological process	GO:0033366	4	1	18204	49	CPE
1.072e-02	-4.54	ovarian cumulus expansion	biological process	GO:0001550	4	1	18204	49	BMPR1B
1.072e-02	-4.54	positive regulation of phospholipid efflux	biological process	GO:1902995	4	1	18204	49	APOE
1.072e-02	-4.54	negative regulation of germ cell proliferation	biological process	GO:1905937	4	1	18204	49	PTGDS
1.072e-02	-4.54	positive regulation of mesenchymal stem cell differentiation	biological process	GO:2000741	4	1	18204	49	SOX5
1.072e-02	-4.54	regulation of phospholipid efflux	biological process	GO:1902994	4	1	18204	49	APOE
1.072e-02	-4.54	response to caloric restriction	biological process	GO:0061771	4	1	18204	49	APOE
1.076e-02	-4.53	FGF_rcpt_fam	interpro domains	IPR016248	4	1	18521	50	FGFR3
1.076e-02	-4.53	CTF/NFI	interpro domains	IPR000647	4	1	18521	50	NFIA
1.076e-02	-4.53	ApoA_E	interpro domains	IPR000074	4	1	18521	50	APOE
1.076e-02	-4.53	CTF/NFI_DNA-bd-dom	interpro domains	IPR020604	4	1	18521	50	NFIA
1.076e-02	-4.53	CTF/NFI_DNA-bd_CS	interpro domains	IPR019739	4	1	18521	50	NFIA
1.076e-02	-4.53	NHS-like	interpro domains	IPR024845	4	1	18521	50	NHSL1
1.076e-02	-4.53	CTF/NFI_DNA-bd_N	interpro domains	IPR019548	4	1	18521	50	NFIA
1.076e-02	-4.53	Na/K-Atpase_Interacting	interpro domains	IPR008516	4	1	18521	50	NKAIN3
1.076e-02	-4.53	P5A-ATPase_N	interpro domains	IPR047819	4	1	18521	50	ATP13A4
1.076e-02	-4.53	Alpha_catenin	interpro domains	IPR001033	4	1	18521	50	CTNNA2
1.076e-02	-4.53	P5B-type_ATPase	interpro domains	IPR047821	4	1	18521	50	ATP13A4
1.082e-02	-4.53	skeletal system development	biological process	GO:0001501	500	5	18204	49	FGFR3,TRPS1,SOX5,BMPR1B,NFIA
1.098e-02	-4.51	primitive_neuroectodermal_tumour-medulloblastoma	COSMIC cancer mutations	primitive_neuroectodermal_tumour-medulloblastoma	15350	49	16828	49	GLUL,BMPR1B,SLC1A2,NPAS3,PTPRZ1,NKAIN3,RORA,RYR3,TNIK,HPSE2,QKI,GPM6A,GPC5,ZBTB20,NFIA,PARD3B,APOE,CPE,PREX2,SLC1A3,PCDH9,PTGDS,ZNRF3,MAML2,GLIS3,NRXN1,COL5A3,PON2,SOX5,SPARCL1,DTNA,CST3,MSI2,FBXL7,AHCYL2,SLC4A4,ATP1A2,CLU,PAMR1,LSAMP,CDH20,NHSL1,PITPNC1,FGFR3,ATP13A4,NTM,HEPACAM,TRPS1,HIF3A
1.101e-02	-4.51	Metabolism of fat-soluble vitamins	REACTOME pathways	R-HSA-6806667	53	2	10285	31	APOE,GPC5
1.101e-02	-4.51	endochondral bone morphogenesis	biological process	GO:0060350	59	2	18204	49	BMPR1B,FGFR3
1.110e-02	-4.50	EPHA4 (EPH receptor A4)	protein interactions	2043	180	3	19454	50	AHCYL2,FGFR3,CTNNA2
1.110e-02	-4.50	MYOD1 (myogenic differentiation 1)	protein interactions	4654	180	3	19454	50	NFIA,RORA,TRPS1
1.115e-02	-4.50	plasma membrane bounded cell projection organization	biological process	GO:0120036	1152	8	18204	49	PTPRZ1,APOE,CTNNA2,BMPR1B,GPM6A,NRXN1,TNIK,PREX2
1.118e-02	-4.49	parathyroid-carcinoma	COSMIC cancer mutations	parathyroid-carcinoma	300	4	16828	49	RYR3,GPC5,TRPS1,PAMR1
1.118e-02	-4.49	parietal_lobe	COSMIC cancer mutations	parietal_lobe	55	2	16828	49	FGFR3,QKI
1.119e-02	-4.49	NfI_DNAbd_pre-N	pfam domains	PF10524	4	1	17795	50	NFIA
1.119e-02	-4.49	P5-ATPase	pfam domains	PF12409	4	1	17795	50	ATP13A4
1.119e-02	-4.49	CTF_NFI	pfam domains	PF00859	4	1	17795	50	NFIA
1.119e-02	-4.49	NKAIN	pfam domains	PF05640	4	1	17795	50	NKAIN3
1.119e-02	-4.49	Apolipoprotein	pfam domains	PF01442	4	1	17795	50	APOE
1.119e-02	-4.49	NHS	pfam domains	PF15273	4	1	17795	50	NHSL1
1.137e-02	-4.48	export across plasma membrane	biological process	GO:0140115	60	2	18204	49	ATP1A2,SLC4A4
1.141e-02	-4.47	Heparan sulfate/heparin (HS-GAG) metabolism	REACTOME pathways	R-HSA-1638091	54	2	10285	31	HPSE2,GPC5
1.143e-02	-4.47	human chr14q13.1	chromosome location	human chr14q13.1	6	1	26134	50	NPAS3
1.143e-02	-4.47	human chr4q34.2	chromosome location	human chr4q34.2	6	1	26134	50	GPM6A
1.144e-02	-4.47	PARAOXONASE	prints domains	PR01785	3	1	5227	20	PON2
1.144e-02	-4.47	RYANODINER	prints domains	PR00795	3	1	5227	20	RYR3
1.144e-02	-4.47	MYELINPLP	prints domains	PR00214	3	1	5227	20	GPM6A
1.144e-02	-4.47	PGNDSYNTHASE	prints domains	PR01254	3	1	5227	20	PTGDS
1.144e-02	-4.47	RORNUCRECPTR	prints domains	PR01293	3	1	5227	20	RORA
1.144e-02	-4.47	NLGN2 (neuroligin 2)	protein interactions	57555	63	2	19454	50	NRXN1,CLU
1.153e-02	-4.46	circulatory system process	biological process	GO:0003013	508	5	18204	49	SLC4A4,ATP1A2,APOE,SLC1A2,SLC1A3
1.153e-02	-4.46	response to endogenous stimulus	biological process	GO:0009719	1402	9	18204	49	ATP1A2,NFIA,RYR3,FGFR3,BMPR1B,SLC1A2,SLC1A3,SOX5,PTGDS
1.160e-02	-4.46	inverted	COSMIC cancer mutations	inverted	4	1	16828	49	FGFR3
1.160e-02	-4.46	skin-benign_melanocytic_nevus-junctional	COSMIC cancer mutations	skin-benign_melanocytic_nevus-junctional	4	1	16828	49	FGFR3
1.160e-02	-4.46	skin-face-malignant_melanoma-superficial_spreading	COSMIC cancer mutations	skin-face-malignant_melanoma-superficial_spreading	4	1	16828	49	PREX2
1.160e-02	-4.46	urinary_tract-bladder-other-normal	COSMIC cancer mutations	urinary_tract-bladder-other-normal	4	1	16828	49	FGFR3
1.160e-02	-4.46	urinary_tract-bladder-papilloma-inverted	COSMIC cancer mutations	urinary_tract-bladder-papilloma-inverted	4	1	16828	49	FGFR3
1.160e-02	-4.46	skin-lower_leg-malignant_melanoma-nodular	COSMIC cancer mutations	skin-lower_leg-malignant_melanoma-nodular	4	1	16828	49	PREX2
1.169e-02	-4.45	MamL-1	smart domains	SM01275	3	1	9717	38	MAML2
1.169e-02	-4.45	PLP	smart domains	SM00002	3	1	9717	38	GPM6A
1.169e-02	-4.45	AdoHcyase	smart domains	SM00996	3	1	9717	38	AHCYL2
1.169e-02	-4.45	AdoHcyase_NAD	smart domains	SM00997	3	1	9717	38	AHCYL2
1.179e-02	-4.44	EVA1C (eva-1 homolog C)	protein interactions	59271	64	2	19454	50	BMPR1B,PCDH9
1.179e-02	-4.44	VSX1 (visual system homeobox 1)	protein interactions	30813	64	2	19454	50	NFIA,TRPS1
1.179e-02	-4.44	SYNC (syncoilin, intermediate filament protein)	protein interactions	81493	64	2	19454	50	MAML2,DTNA
1.184e-02	-4.44	upper_aerodigestive_tract-mouth-carcinoma	COSMIC cancer mutations	upper_aerodigestive_tract-mouth-carcinoma	6426	27	16828	49	COL5A3,NPAS3,SLC1A2,RORA,SOX5,HPSE2,RYR3,QKI,GPM6A,ZBTB20,GPC5,FBXL7,SLC4A4,PARD3B,CLU,PAMR1,APOE,NHSL1,CDH20,SLC1A3,PREX2,PITPNC1,FGFR3,NTM,MAML2,TRPS1,HIF3A
1.190e-02	-4.43	biliary_tract-gallbladder-carcinoma-adenocarcinoma	COSMIC cancer mutations	biliary_tract-gallbladder-carcinoma-adenocarcinoma	2821	15	16828	49	SPARCL1,RYR3,TNIK,ZNRF3,FGFR3,PCDH9,TRPS1,COL5A3,CLU,SLC4A4,NKAIN3,PITPNC1,PTPRZ1,PREX2,NHSL1
1.190e-02	-4.43	gallbladder	COSMIC cancer mutations	gallbladder	2821	15	16828	49	SLC4A4,CLU,COL5A3,NHSL1,PTPRZ1,PREX2,PITPNC1,NKAIN3,FGFR3,PCDH9,ZNRF3,RYR3,TNIK,SPARCL1,TRPS1
1.196e-02	-4.43	regulation of small molecule metabolic process	biological process	GO:0062012	331	4	18204	49	RORA,APOE,SLC4A4,ZBTB20
1.205e-02	-4.42	TRIM67 (tripartite motif containing 67)	protein interactions	440730	4804	20	19454	50	TNIK,PITPNC1,DTNA,CST3,PON2,SLC4A4,QKI,MSI2,HEPACAM,NTM,CLU,PTPRZ1,GPM6A,AHCYL2,LSAMP,GLUL,ATP1A2,CTNNA2,SLC1A3,APOE
1.211e-02	-4.41	regulation of carbohydrate catabolic process	biological process	GO:0043470	62	2	18204	49	SLC4A4,ZBTB20
1.212e-02	-4.41	skin-face-carcinoma-squamous_cell_carcinoma	COSMIC cancer mutations	skin-face-carcinoma-squamous_cell_carcinoma	2036	12	16828	49	PCDH9,FGFR3,RORA,ZNRF3,HEPACAM,TRPS1,GPC5,MSI2,GPM6A,LSAMP,PREX2,PTPRZ1
1.216e-02	-4.41	parathyroid	COSMIC cancer mutations	parathyroid	476	5	16828	49	RYR3,GPC5,GPM6A,TRPS1,PAMR1
1.224e-02	-4.40	Ion homeostasis	REACTOME pathways	R-HSA-5578775	56	2	10285	31	RYR3,ATP1A2
1.230e-02	-4.40	KLF5 (KLF transcription factor 5)	protein interactions	688	187	3	19454	50	NFIA,CLU,TRPS1
1.237e-02	-4.39	lipid homeostasis	biological process	GO:0055088	179	3	18204	49	ZBTB20,RORA,APOE
1.239e-02	-4.39	adherens junction	cellular component	GO:0005912	188	3	19108	49	CDH20,CTNNA2,PARD3B
1.248e-02	-4.38	HNF1B (HNF1 homeobox B)	protein interactions	6928	188	3	19454	50	TRPS1,SOX5,NFIA
1.249e-02	-4.38	regulation of nitric oxide biosynthetic process	biological process	GO:0045428	63	2	18204	49	CLU,APOE
1.249e-02	-4.38	back	COSMIC cancer mutations	back	310	4	16828	49	TNIK,ATP1A2,PREX2,FGFR3
1.250e-02	-4.38	ORM1 (orosomucoid 1)	protein interactions	5004	66	2	19454	50	PTGDS,CLU
1.250e-02	-4.38	MICB (MHC class I polypeptide-related sequence B)	protein interactions	4277	66	2	19454	50	APOE,CLU
1.250e-02	-4.38	MAML1 (mastermind like transcriptional coactivator 1)	protein interactions	9794	66	2	19454	50	NFIA,MAML2
1.254e-02	-4.38	Erythroid Transcription Factor GATA-1, subunit A	gene3d domains	3.30.50.10	56	2	14470	44	RORA,TRPS1
1.275e-02	-4.36	L-amino acid transmembrane transporter activity	molecular function	GO:0015179	66	2	18094	47	SLC1A3,SLC1A2
1.276e-02	-4.36	neurofibrillary tangle	cellular component	GO:0097418	5	1	19108	49	CLU
1.279e-02	-4.36	Hk3 (hexokinase 3)	protein interactions	25060	5	1	19454	50	PTGDS
1.279e-02	-4.36	Cdk4 (cyclin dependent kinase 4)	protein interactions	12567	5	1	19454	50	BMPR1B
1.279e-02	-4.36	EPPIN (epididymal peptidase inhibitor)	protein interactions	57119	5	1	19454	50	CLU
1.279e-02	-4.36	ARSI (arylsulfatase family member I)	protein interactions	340075	5	1	19454	50	AHCYL2
1.279e-02	-4.36	Rhoj (ras homolog family member J)	protein interactions	80837	5	1	19454	50	BMPR1B
1.279e-02	-4.36	Wwp2 (WW domain containing E3 ubiquitin protein ligase 2)	protein interactions	66894	5	1	19454	50	GLIS3
1.279e-02	-4.36	SYT13 (synaptotagmin 13)	protein interactions	57586	5	1	19454	50	NRXN1
1.279e-02	-4.36	ADCYAP1R1 (ADCYAP receptor type I)	protein interactions	117	5	1	19454	50	CLU
1.279e-02	-4.36	Rras2 (related RAS viral (r-ras) oncogene 2)	protein interactions	66922	5	1	19454	50	BMPR1B
1.279e-02	-4.36	Rhobtb1 (Rho-related BTB domain containing 1)	protein interactions	69288	5	1	19454	50	BMPR1B
1.279e-02	-4.36	Rab38 (RAB38, member RAS oncogene family)	protein interactions	72433	5	1	19454	50	BMPR1B
1.279e-02	-4.36	Rab6b (RAB6B, member RAS oncogene family)	protein interactions	270192	5	1	19454	50	BMPR1B
1.279e-02	-4.36	PTGER2 (prostaglandin E receptor 2)	protein interactions	5732	5	1	19454	50	PTGDS
1.279e-02	-4.36	TRH (thyrotropin releasing hormone)	protein interactions	7200	5	1	19454	50	CPE
1.283e-02	-4.36	small molecule binding	molecular function	GO:0036094	6197	24	18094	47	GLIS3,ATP1A2,ZNRF3,BMPR1B,PON2,SLC1A3,FGFR3,TNIK,ZBTB20,ATP13A4,DTNA,GLUL,RORA,RYR3,SLC1A2,APOE,SPARCL1,NRXN1,PITPNC1,TRPS1,CPE,PCDH9,PAMR1,PTGDS
1.287e-02	-4.35	dendrite morphogenesis	biological process	GO:0048813	64	2	18204	49	PREX2,CTNNA2
1.292e-02	-4.35	neuroligin family protein binding	molecular function	GO:0097109	5	1	18094	47	NRXN1
1.292e-02	-4.35	fibroblast growth factor receptor activity	molecular function	GO:0005007	5	1	18094	47	FGFR3
1.292e-02	-4.35	transforming growth factor beta receptor activity, type I	molecular function	GO:0005025	5	1	18094	47	BMPR1B
1.302e-02	-4.34	pancreas-carcinoma	COSMIC cancer mutations	pancreas-carcinoma	14770	48	16828	49	PTGDS,ZNRF3,PCDH9,MAML2,GLIS3,NRXN1,CPE,APOE,PARD3B,SLC1A3,PREX2,QKI,RORA,HPSE2,RYR3,TNIK,NFIA,GPM6A,ZBTB20,GPC5,BMPR1B,GLUL,NKAIN3,NPAS3,SLC1A2,PTPRZ1,ATP13A4,FGFR3,NTM,HEPACAM,TRPS1,HIF3A,PAMR1,LSAMP,AHCYL2,SLC4A4,ATP1A2,CLU,PITPNC1,NHSL1,CDH20,SPARCL1,SOX5,FBXL7,CST3,MSI2,COL5A3,PON2
1.309e-02	-4.34	Ion transport by P-type ATPases	REACTOME pathways	R-HSA-936837	58	2	10285	31	ATP1A2,ATP13A4
1.310e-02	-4.34	central_nervous_system-brain-primitive_neuroectodermal_tumour-medulloblastoma-medullomyoblastoma	COSMIC cancer mutations	central_nervous_system-brain-primitive_neuroectodermal_tumour-medulloblastoma-medullomyoblastoma	485	5	16828	49	PCDH9,SLC4A4,ATP13A4,RYR3,LSAMP
1.310e-02	-4.34	medullomyoblastoma	COSMIC cancer mutations	medullomyoblastoma	485	5	16828	49	SLC4A4,PCDH9,ATP13A4,RYR3,LSAMP
1.312e-02	-4.33	regulation of carbohydrate metabolic process	biological process	GO:0006109	183	3	18204	49	SLC4A4,RORA,ZBTB20
1.317e-02	-4.33	upper_leg	COSMIC cancer mutations	upper_leg	880	7	16828	49	PCDH9,FGFR3,PAMR1,GLIS3,PREX2,NFIA,HIF3A
1.325e-02	-4.32	regulation of nitric oxide metabolic process	biological process	GO:0080164	65	2	18204	49	APOE,CLU
1.328e-02	-4.32	positive regulation of multicellular organismal process	biological process	GO:0051240	1691	10	18204	49	CLU,ATP1A2,APOE,ZBTB20,NRXN1,BMPR1B,RORA,QKI,PTPRZ1,SOX5
1.332e-02	-4.32	human chr13q21.32	chromosome location	human chr13q21.32	7	1	26134	50	PCDH9
1.332e-02	-4.32	human chr8q13.2	chromosome location	human chr8q13.2	7	1	26134	50	PREX2
1.339e-02	-4.31	amygdala development	biological process	GO:0021764	5	1	18204	49	ATP1A2
1.339e-02	-4.31	gephyrin clustering involved in postsynaptic density assembly	biological process	GO:0097116	5	1	18204	49	NRXN1
1.339e-02	-4.31	AMPA glutamate receptor clustering	biological process	GO:0097113	5	1	18204	49	APOE
1.339e-02	-4.31	central nervous system myelin maintenance	biological process	GO:0032286	5	1	18204	49	CLU
1.339e-02	-4.31	chylomicron remnant clearance	biological process	GO:0034382	5	1	18204	49	APOE
1.339e-02	-4.31	glutamate receptor clustering	biological process	GO:0097688	5	1	18204	49	APOE
1.339e-02	-4.31	negative regulation of chondrocyte proliferation	biological process	GO:1902731	5	1	18204	49	BMPR1B
1.339e-02	-4.31	positive regulation of dendritic spine maintenance	biological process	GO:1902952	5	1	18204	49	APOE
1.343e-02	-4.31	PI_transfer	interpro domains	IPR001666	5	1	18521	50	PITPNC1
1.343e-02	-4.31	Follistatin/Osteonectin_EGF	interpro domains	IPR015369	5	1	18521	50	SPARCL1
1.343e-02	-4.31	BBP-like	interpro domains	IPR045071	5	1	18521	50	QKI
1.343e-02	-4.31	Na/HCO3_transpt	interpro domains	IPR003024	5	1	18521	50	SLC4A4
1.343e-02	-4.31	Vinculin/catenin	interpro domains	IPR006077	5	1	18521	50	CTNNA2
1.343e-02	-4.31	Protocadherin	interpro domains	IPR013585	5	1	18521	50	PCDH9
1.343e-02	-4.31	P-type_TPase_V	interpro domains	IPR006544	5	1	18521	50	ATP13A4
1.349e-02	-4.31	collagen binding	molecular function	GO:0005518	68	2	18094	47	COL5A3,SPARCL1
1.352e-02	-4.30	Arachidonic acid metabolism	REACTOME pathways	R-HSA-2142753	59	2	10285	31	PON2,PTGDS
1.356e-02	-4.30	arm	COSMIC cancer mutations	arm	1331	9	16828	49	NPAS3,ZBTB20,TRPS1,SLC4A4,FGFR3,ATP1A2,NTM,PARD3B,COL5A3
1.364e-02	-4.29	L-alpha-amino acid transmembrane transport	biological process	GO:1902475	66	2	18204	49	SLC1A3,SLC1A2
1.365e-02	-4.29	blood vessel development	biological process	GO:0001568	530	5	18204	49	GLUL,HIF3A,QKI,RORA,APOE
1.367e-02	-4.29	neoplasm	COSMIC cancer mutations	neoplasm	14787	48	16828	49	HIF3A,TRPS1,HEPACAM,NTM,FGFR3,ATP13A4,CDH20,NHSL1,LSAMP,PAMR1,CLU,ATP1A2,SLC4A4,AHCYL2,FBXL7,MSI2,CST3,DTNA,SPARCL1,SOX5,PON2,COL5A3,NRXN1,GLIS3,MAML2,PCDH9,PTGDS,ZNRF3,SLC1A3,PREX2,APOE,CPE,PARD3B,NFIA,GPC5,ZBTB20,GPM6A,QKI,TNIK,RYR3,HPSE2,RORA,NKAIN3,PTPRZ1,SLC1A2,NPAS3,BMPR1B,GLUL
1.368e-02	-4.29	IGc2	smart domains	SM00408	239	4	9717	38	HEPACAM,LSAMP,NTM,FGFR3
1.372e-02	-4.29	CTF_NFI_1	prosite domains	PS00349	4	1	12186	42	NFIA
1.372e-02	-4.29	CTF_NFI_2	prosite domains	PS51080	4	1	12186	42	NFIA
1.397e-02	-4.27	FOLN	pfam domains	PF09289	5	1	17795	50	SPARCL1
1.397e-02	-4.27	Protocadherin	pfam domains	PF08374	5	1	17795	50	PCDH9
1.397e-02	-4.27	Vinculin	pfam domains	PF01044	5	1	17795	50	CTNNA2
1.397e-02	-4.27	IP_trans	pfam domains	PF02121	5	1	17795	50	PITPNC1
1.399e-02	-4.27	PCDH20 (protocadherin 20)	protein interactions	64881	70	2	19454	50	PON2,CTNNA2
1.400e-02	-4.27	adenoma	COSMIC cancer mutations	adenoma	2873	15	16828	49	GPC5,ZBTB20,GPM6A,HIF3A,RYR3,HPSE2,SOX5,PCDH9,FGFR3,PTPRZ1,CDH20,NPAS3,BMPR1B,APOE,COL5A3
1.403e-02	-4.27	cell projection organization	biological process	GO:0030030	1200	8	18204	49	CTNNA2,BMPR1B,PTPRZ1,APOE,PREX2,GPM6A,NRXN1,TNIK
1.404e-02	-4.27	cholesterol transport	biological process	GO:0030301	67	2	18204	49	APOE,CLU
1.405e-02	-4.27	monoatomic ion transport	biological process	GO:0006811	964	7	18204	49	ATP13A4,RYR3,SLC4A4,ATP1A2,GPM6A,SLC1A3,SLC1A2
1.418e-02	-4.26	liver-carcinoma-hepatocellular_carcinoma	COSMIC cancer mutations	liver-carcinoma-hepatocellular_carcinoma	14800	48	16828	49	ZNRF3,PTGDS,PCDH9,MAML2,GLIS3,NRXN1,CPE,APOE,PARD3B,PREX2,SLC1A3,QKI,RORA,HPSE2,TNIK,RYR3,NFIA,GPM6A,ZBTB20,GPC5,BMPR1B,GLUL,NKAIN3,NPAS3,SLC1A2,PTPRZ1,ATP13A4,FGFR3,NTM,TRPS1,HEPACAM,HIF3A,PAMR1,LSAMP,AHCYL2,SLC4A4,CLU,ATP1A2,PITPNC1,NHSL1,CDH20,SPARCL1,SOX5,FBXL7,DTNA,CST3,COL5A3,PON2
1.418e-02	-4.26	hepatocellular_carcinoma	COSMIC cancer mutations	hepatocellular_carcinoma	14800	48	16828	49	SLC1A3,PREX2,PARD3B,APOE,CPE,NRXN1,GLIS3,MAML2,PCDH9,PTGDS,ZNRF3,PTPRZ1,SLC1A2,NPAS3,NKAIN3,GLUL,BMPR1B,GPC5,ZBTB20,GPM6A,NFIA,RYR3,TNIK,HPSE2,RORA,QKI,CDH20,NHSL1,PITPNC1,CLU,ATP1A2,AHCYL2,SLC4A4,LSAMP,PAMR1,HIF3A,TRPS1,HEPACAM,NTM,FGFR3,ATP13A4,PON2,COL5A3,DTNA,CST3,FBXL7,SOX5,SPARCL1
1.433e-02	-4.25	NFIX (nuclear factor I X)	protein interactions	4784	198	3	19454	50	NFIA,SOX5,TRPS1
1.437e-02	-4.24	ANK2 (ankyrin 2)	protein interactions	287	71	2	19454	50	TNIK,GPM6A
1.437e-02	-4.24	UNKL (unk like zinc finger)	protein interactions	64718	71	2	19454	50	AHCYL2,QKI
1.448e-02	-4.24	skin-neck-other-nevus_sebaceous	COSMIC cancer mutations	skin-neck-other-nevus_sebaceous	5	1	16828	49	FGFR3
1.448e-02	-4.24	skin-hand-other-lichenoid_keratosis	COSMIC cancer mutations	skin-hand-other-lichenoid_keratosis	5	1	16828	49	FGFR3
1.448e-02	-4.24	skin-lower_back-other-nevus_sebaceous	COSMIC cancer mutations	skin-lower_back-other-nevus_sebaceous	5	1	16828	49	FGFR3
1.448e-02	-4.24	skin-adnexal_tumour-syringocystadenoma_papilliferum	COSMIC cancer mutations	skin-adnexal_tumour-syringocystadenoma_papilliferum	5	1	16828	49	FGFR3
1.448e-02	-4.24	syringocystadenoma_papilliferum	COSMIC cancer mutations	syringocystadenoma_papilliferum	5	1	16828	49	FGFR3
1.448e-02	-4.24	skin-upper_back-other-lichenoid_keratosis	COSMIC cancer mutations	skin-upper_back-other-lichenoid_keratosis	5	1	16828	49	FGFR3
1.448e-02	-4.24	skin-lower_leg-malignant_melanoma-superficial_spreading	COSMIC cancer mutations	skin-lower_leg-malignant_melanoma-superficial_spreading	5	1	16828	49	PREX2
1.448e-02	-4.24	monoclonal_gammopathy_of_undetermined_significance	COSMIC cancer mutations	monoclonal_gammopathy_of_undetermined_significance	5	1	16828	49	FGFR3
1.448e-02	-4.24	skin-upper_leg-other-lichenoid_keratosis	COSMIC cancer mutations	skin-upper_leg-other-lichenoid_keratosis	5	1	16828	49	FGFR3
1.448e-02	-4.24	skin-flank-other-lichenoid_keratosis	COSMIC cancer mutations	skin-flank-other-lichenoid_keratosis	5	1	16828	49	FGFR3
1.448e-02	-4.24	skin-upper_arm-other-lichenoid_keratosis	COSMIC cancer mutations	skin-upper_arm-other-lichenoid_keratosis	5	1	16828	49	FGFR3
1.448e-02	-4.24	skin-lower_leg-other-lichenoid_keratosis	COSMIC cancer mutations	skin-lower_leg-other-lichenoid_keratosis	5	1	16828	49	FGFR3
1.448e-02	-4.24	skin-face-other-lichenoid_keratosis	COSMIC cancer mutations	skin-face-other-lichenoid_keratosis	5	1	16828	49	FGFR3
1.448e-02	-4.24	skin-scalp-other-nevus_sebaceous	COSMIC cancer mutations	skin-scalp-other-nevus_sebaceous	5	1	16828	49	FGFR3
1.448e-02	-4.24	skin-breast-other-lichenoid_keratosis	COSMIC cancer mutations	skin-breast-other-lichenoid_keratosis	5	1	16828	49	FGFR3
1.448e-02	-4.24	skin-breast-other-nevus_sebaceous	COSMIC cancer mutations	skin-breast-other-nevus_sebaceous	5	1	16828	49	FGFR3
1.448e-02	-4.24	skin-hip-other-seborrhoeic_keratosis	COSMIC cancer mutations	skin-hip-other-seborrhoeic_keratosis	5	1	16828	49	FGFR3
1.448e-02	-4.24	skin-shoulder-other-nevus_sebaceous	COSMIC cancer mutations	skin-shoulder-other-nevus_sebaceous	5	1	16828	49	FGFR3
1.448e-02	-4.24	skin-lower_back-other-lichenoid_keratosis	COSMIC cancer mutations	skin-lower_back-other-lichenoid_keratosis	5	1	16828	49	FGFR3
1.448e-02	-4.24	skin-face-other-nevus_sebaceous	COSMIC cancer mutations	skin-face-other-nevus_sebaceous	5	1	16828	49	FGFR3
1.448e-02	-4.24	skin-forearm-other-seborrhoeic_keratosis	COSMIC cancer mutations	skin-forearm-other-seborrhoeic_keratosis	5	1	16828	49	FGFR3
1.448e-02	-4.24	skin-forearm-other-lichenoid_keratosis	COSMIC cancer mutations	skin-forearm-other-lichenoid_keratosis	5	1	16828	49	FGFR3
1.448e-02	-4.24	skin-other-lichenoid_keratosis	COSMIC cancer mutations	skin-other-lichenoid_keratosis	5	1	16828	49	FGFR3
1.448e-02	-4.24	skin-ear-other-nevus_sebaceous	COSMIC cancer mutations	skin-ear-other-nevus_sebaceous	5	1	16828	49	FGFR3
1.448e-02	-4.24	skin-neck-other-lichenoid_keratosis	COSMIC cancer mutations	skin-neck-other-lichenoid_keratosis	5	1	16828	49	FGFR3
1.448e-02	-4.24	skin-chest-other-lichenoid_keratosis	COSMIC cancer mutations	skin-chest-other-lichenoid_keratosis	5	1	16828	49	FGFR3
1.448e-02	-4.24	lichenoid_keratosis	COSMIC cancer mutations	lichenoid_keratosis	5	1	16828	49	FGFR3
1.448e-02	-4.24	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-monoclonal_gammopathy_of_undetermined_significance	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-monoclonal_gammopathy_of_undetermined_significance	5	1	16828	49	FGFR3
1.448e-02	-4.24	skin-shoulder-other-lichenoid_keratosis	COSMIC cancer mutations	skin-shoulder-other-lichenoid_keratosis	5	1	16828	49	FGFR3
1.448e-02	-4.24	skin-arm-other-seborrhoeic_keratosis	COSMIC cancer mutations	skin-arm-other-seborrhoeic_keratosis	5	1	16828	49	FGFR3
1.467e-02	-4.22	cell adhesion molecule binding	molecular function	GO:0050839	560	5	18094	47	CDH20,NRXN1,CTNNA2,PTPRZ1,CPE
1.476e-02	-4.22	DPYSL3 (dihydropyrimidinase like 3)	protein interactions	1809	72	2	19454	50	TNIK,GPM6A
1.476e-02	-4.22	PPP3CC (protein phosphatase 3 catalytic subunit gamma)	protein interactions	5533	72	2	19454	50	PARD3B,BMPR1B
1.480e-02	-4.21	EGF	pfam domains	PF00008	66	2	17795	50	PAMR1,NRXN1
1.488e-02	-4.21	human chr19q13.32	chromosome location	human chr19q13.32	97	2	26134	50	APOE,HIF3A
1.492e-02	-4.21	TIAM1 (TIAM Rac1 associated GEF 1)	protein interactions	7074	201	3	19454	50	DTNA,ATP1A2,RYR3
1.511e-02	-4.19	Apolipoprotein	gene3d domains	1.20.120.20	5	1	14470	44	APOE
1.512e-02	-4.19	FEV (FEV transcription factor, ETS family member)	protein interactions	54738	202	3	19454	50	TRPS1,SOX5,NFIA
1.520e-02	-4.19	ORF3a (ORF3a protein)	protein interactions	43740569	789	6	19454	50	BMPR1B,ZNRF3,CLU,PARD3B,PCDH9,SLC4A4
1.521e-02	-4.19	plasma membrane region	cellular component	GO:0098590	1278	8	19108	49	ATP1A2,SLC4A4,PARD3B,TNIK,SLC1A3,NRXN1,GPM6A,SLC1A2
1.522e-02	-4.19	ALPHACATENIN	prints domains	PR00805	4	1	5227	20	CTNNA2
1.529e-02	-4.18	multivesicular body, internal vesicle	cellular component	GO:0097487	6	1	19108	49	APOE
1.532e-02	-4.18	Map2k3 (mitogen-activated protein kinase kinase 3)	protein interactions	26397	6	1	19454	50	BMPR1B
1.532e-02	-4.18	RSPO3 (R-spondin 3)	protein interactions	84870	6	1	19454	50	ZNRF3
1.532e-02	-4.18	TAT (tyrosine aminotransferase)	protein interactions	6898	6	1	19454	50	GLUL
1.532e-02	-4.18	FGF6 (fibroblast growth factor 6)	protein interactions	2251	6	1	19454	50	FGFR3
1.532e-02	-4.18	Fancl (Fanconi anemia, complementation group L)	protein interactions	67030	6	1	19454	50	BMPR1B
1.532e-02	-4.18	SLC12A5 (solute carrier family 12 member 5)	protein interactions	57468	6	1	19454	50	GPM6A
1.532e-02	-4.18	FGF23 (fibroblast growth factor 23)	protein interactions	8074	6	1	19454	50	FGFR3
1.532e-02	-4.18	SOX11 (SRY-box transcription factor 11)	protein interactions	6664	6	1	19454	50	SOX5
1.532e-02	-4.18	CYRIA (CYFIP related Rac1 interactor A)	protein interactions	81553	6	1	19454	50	GPM6A
1.532e-02	-4.18	Tiam2 (T cell lymphoma invasion and metastasis 2)	protein interactions	24001	6	1	19454	50	DTNA
1.532e-02	-4.18	Itch (itchy, E3 ubiquitin protein ligase)	protein interactions	16396	6	1	19454	50	GLIS3
1.532e-02	-4.18	LCAT (lecithin-cholesterol acyltransferase)	protein interactions	3931	6	1	19454	50	APOE
1.532e-02	-4.18	GDF6 (growth differentiation factor 6)	protein interactions	392255	6	1	19454	50	BMPR1B
1.532e-02	-4.18	PBP2 (Pbp2p)	protein interactions	852533	6	1	19454	50	QKI
1.532e-02	-4.18	Taok2 (TAO kinase 2)	protein interactions	381921	6	1	19454	50	CLU
1.532e-02	-4.18	DRP2 (dystrophin related protein 2)	protein interactions	1821	6	1	19454	50	DTNA
1.532e-02	-4.18	SOX1 (SRY-box transcription factor 1)	protein interactions	6656	6	1	19454	50	SOX5
1.532e-02	-4.18	CYP39A1 (cytochrome P450 family 39 subfamily A member 1)	protein interactions	51302	6	1	19454	50	GLUL
1.532e-02	-4.18	FXYD7 (FXYD domain containing ion transport regulator 7)	protein interactions	53822	6	1	19454	50	APOE
1.532e-02	-4.18	Rhod (ras homolog family member D)	protein interactions	11854	6	1	19454	50	BMPR1B
1.532e-02	-4.18	DAZ4 (deleted in azoospermia 4)	protein interactions	57135	6	1	19454	50	QKI
1.532e-02	-4.18	SYTL3 (synaptotagmin like 3)	protein interactions	94120	6	1	19454	50	NRXN1
1.532e-02	-4.18	FGF18 (fibroblast growth factor 18)	protein interactions	8817	6	1	19454	50	FGFR3
1.535e-02	-4.18	cell-cell adhesion	biological process	GO:0098609	546	5	18204	49	CDH20,NRXN1,PCDH9,CTNNA2,SPARCL1
1.547e-02	-4.17	C20 prostanoid biosynthesis	BIOCYC pathways	META_PWY66-374	7	1	902	2	PTGDS
1.547e-02	-4.17	C20 prostanoid biosynthesis	BIOCYC pathways	HUMAN_PWY66-374	7	1	902	2	PTGDS
1.547e-02	-4.17	cell-cell contact zone	cellular component	GO:0044291	74	2	19108	49	ATP1A2,PCDH9
1.549e-02	-4.17	sodium:bicarbonate symporter activity	molecular function	GO:0008510	6	1	18094	47	SLC4A4
1.549e-02	-4.17	arylesterase activity	molecular function	GO:0004064	6	1	18094	47	PON2
1.549e-02	-4.17	phosphatidylcholine-sterol O-acyltransferase activator activity	molecular function	GO:0060228	6	1	18094	47	APOE
1.549e-02	-4.17	calcium-induced calcium release activity	molecular function	GO:0048763	6	1	18094	47	RYR3
1.549e-02	-4.17	steroid hormone binding	molecular function	GO:1990239	6	1	18094	47	ATP1A2
1.552e-02	-4.17	CASK (calcium/calmodulin dependent serine protein kinase)	protein interactions	8573	204	3	19454	50	NRXN1,DTNA,PARD3B
1.552e-02	-4.17	NFIC (nuclear factor I C)	protein interactions	4782	204	3	19454	50	TRPS1,SOX5,NFIA
1.554e-02	-4.16	CACNA2D1 (calcium voltage-gated channel auxiliary subunit alpha2delta 1)	protein interactions	781	74	2	19454	50	GPM6A,PON2
1.579e-02	-4.15	vasculature development	biological process	GO:0001944	550	5	18204	49	RORA,APOE,QKI,HIF3A,GLUL
1.597e-02	-4.14	locomotory behavior	biological process	GO:0007626	197	3	18204	49	PREX2,APOE,ATP1A2
1.597e-02	-4.14	Synaptic Vesicle Pathway	WikiPathways	WP2267	52	2	5310	20	SLC1A3,ATP1A2
1.600e-02	-4.13	other	COSMIC cancer mutations	other	14843	48	16828	49	NKAIN3,PTPRZ1,NPAS3,SLC1A2,BMPR1B,GLUL,NFIA,ZBTB20,GPC5,GPM6A,QKI,HPSE2,TNIK,RYR3,RORA,SLC1A3,PREX2,CPE,APOE,PARD3B,NRXN1,GLIS3,MAML2,PTGDS,ZNRF3,PCDH9,PON2,COL5A3,FBXL7,MSI2,DTNA,CST3,SPARCL1,SOX5,NHSL1,CDH20,LSAMP,PAMR1,CLU,ATP1A2,SLC4A4,AHCYL2,HIF3A,TRPS1,HEPACAM,NTM,ATP13A4,FGFR3
1.604e-02	-4.13	postsynaptic density protein 95 clustering	biological process	GO:0097119	6	1	18204	49	NRXN1
1.604e-02	-4.13	imitative learning	biological process	GO:0098596	6	1	18204	49	NRXN1
1.604e-02	-4.13	negative regulation of extracellular matrix disassembly	biological process	GO:0010716	6	1	18204	49	CST3
1.604e-02	-4.13	vocal learning	biological process	GO:0042297	6	1	18204	49	NRXN1
1.604e-02	-4.13	asymmetric neuroblast division	biological process	GO:0055059	6	1	18204	49	SOX5
1.604e-02	-4.13	regulation of low-density lipoprotein particle receptor catabolic process	biological process	GO:0032803	6	1	18204	49	APOE
1.604e-02	-4.13	gamma-aminobutyric acid biosynthetic process	biological process	GO:0009449	6	1	18204	49	SLC1A3
1.604e-02	-4.13	triglyceride-rich lipoprotein particle clearance	biological process	GO:0071830	6	1	18204	49	APOE
1.604e-02	-4.13	protein targeting to vacuole involved in autophagy	biological process	GO:0071211	6	1	18204	49	CLU
1.604e-02	-4.13	fused antrum stage	biological process	GO:0048165	6	1	18204	49	BMPR1B
1.609e-02	-4.13	RyR/IP3R_RIH_dom_sf	interpro domains	IPR035910	6	1	18521	50	RYR3
1.609e-02	-4.13	Ryanodine_IP3_receptor	interpro domains	IPR015925	6	1	18521	50	RYR3
1.609e-02	-4.13	EF-hand_dom_typ2	interpro domains	IPR015154	6	1	18521	50	DTNA
1.609e-02	-4.13	RIH_dom	interpro domains	IPR000699	6	1	18521	50	RYR3
1.609e-02	-4.13	Glypican	interpro domains	IPR001863	6	1	18521	50	GPC5
1.609e-02	-4.13	P-type_ATPase_IIC	interpro domains	IPR005775	6	1	18521	50	ATP1A2
1.609e-02	-4.13	EF-hand_dom_typ1	interpro domains	IPR015153	6	1	18521	50	DTNA
1.609e-02	-4.13	Glypican_CS	interpro domains	IPR019803	6	1	18521	50	GPC5
1.609e-02	-4.13	Syndecan/Neurexin_dom	interpro domains	IPR027789	6	1	18521	50	NRXN1
1.609e-02	-4.13	GLI-like	interpro domains	IPR043359	6	1	18521	50	GLIS3
1.609e-02	-4.13	Ins145_P3_rcpt	interpro domains	IPR014821	6	1	18521	50	RYR3
1.609e-02	-4.13	RIH_assoc-dom	interpro domains	IPR013662	6	1	18521	50	RYR3
1.609e-02	-4.13	regulation of ATP metabolic process	biological process	GO:1903578	72	2	18204	49	SLC4A4,ZBTB20
1.616e-02	-4.13	bone-femur-other-chondroblastoma	COSMIC cancer mutations	bone-femur-other-chondroblastoma	183	3	16828	49	GPC5,RYR3,PCDH9
1.618e-02	-4.12	skin-trunk-malignant_melanoma	COSMIC cancer mutations	skin-trunk-malignant_melanoma	2647	14	16828	49	TRPS1,NRXN1,ATP13A4,PCDH9,SOX5,MAML2,HPSE2,RYR3,CDH20,PREX2,PTPRZ1,SLC1A3,LSAMP,ATP1A2
1.632e-02	-4.12	monoatomic cation transport	biological process	GO:0006812	766	6	18204	49	GPM6A,SLC1A3,RYR3,ATP13A4,SLC4A4,ATP1A2
1.633e-02	-4.11	RYK (receptor like tyrosine kinase)	protein interactions	6259	208	3	19454	50	CTNNA2,CLU,PCDH9
1.635e-02	-4.11	MIR200A (microRNA 200a)	protein interactions	406983	76	2	19454	50	MSI2,QKI
1.652e-02	-4.10	peptide metabolic process	biological process	GO:0006518	73	2	18204	49	CPE,SLC1A2
1.673e-02	-4.09	axonogenesis	biological process	GO:0007409	366	4	18204	49	NRXN1,PTPRZ1,BMPR1B,CTNNA2
1.674e-02	-4.09	RIH_assoc	pfam domains	PF08454	6	1	17795	50	RYR3
1.674e-02	-4.09	RYDR_ITPR	pfam domains	PF01365	6	1	17795	50	RYR3
1.674e-02	-4.09	Glypican	pfam domains	PF01153	6	1	17795	50	GPC5
1.674e-02	-4.09	EF-hand_2	pfam domains	PF09068	6	1	17795	50	DTNA
1.674e-02	-4.09	Ins145_P3_rec	pfam domains	PF08709	6	1	17795	50	RYR3
1.674e-02	-4.09	Syndecan	pfam domains	PF01034	6	1	17795	50	NRXN1
1.674e-02	-4.09	EF-hand_3	pfam domains	PF09069	6	1	17795	50	DTNA
1.695e-02	-4.08	sterol transport	biological process	GO:0015918	74	2	18204	49	APOE,CLU
1.695e-02	-4.08	positive regulation of gliogenesis	biological process	GO:0014015	74	2	18204	49	PTPRZ1,QKI
1.705e-02	-4.07	HAD_sf	interpro domains	IPR023214	74	2	18521	50	ATP1A2,ATP13A4
1.706e-02	-4.07	intracellular calcium ion homeostasis	biological process	GO:0006874	202	3	18204	49	ATP13A4,RYR3,APOE
1.709e-02	-4.07	human chr4q22.3	chromosome location	human chr4q22.3	9	1	26134	50	BMPR1B
1.715e-02	-4.07	extremity	COSMIC cancer mutations	extremity	1876	11	16828	49	PREX2,PTPRZ1,CDH20,PITPNC1,COL5A3,FBXL7,RYR3,HPSE2,PCDH9,FGFR3,ATP13A4
1.717e-02	-4.06	LRP8 (LDL receptor related protein 8)	protein interactions	7804	78	2	19454	50	CLU,APOE
1.717e-02	-4.06	MIR34C (microRNA 34c)	protein interactions	407042	78	2	19454	50	QKI,MSI2
1.717e-02	-4.06	IFIT3 (interferon induced protein with tetratricopeptide repeats 3)	protein interactions	3437	78	2	19454	50	ATP1A2,APOE
1.717e-02	-4.06	ANKRD40 (ankyrin repeat domain 40)	protein interactions	91369	78	2	19454	50	MSI2,SOX5
1.735e-02	-4.05	lentiginous_nevus	COSMIC cancer mutations	lentiginous_nevus	6	1	16828	49	FGFR3
1.735e-02	-4.05	skin-upper_leg-other-seborrhoeic_keratosis	COSMIC cancer mutations	skin-upper_leg-other-seborrhoeic_keratosis	6	1	16828	49	FGFR3
1.735e-02	-4.05	autonomic_ganglia-paraganglioma-benign	COSMIC cancer mutations	autonomic_ganglia-paraganglioma-benign	6	1	16828	49	NHSL1
1.735e-02	-4.05	skin-arm-epidermal_nevus	COSMIC cancer mutations	skin-arm-epidermal_nevus	6	1	16828	49	FGFR3
1.735e-02	-4.05	skin-forearm-malignant_melanoma-superficial_spreading	COSMIC cancer mutations	skin-forearm-malignant_melanoma-superficial_spreading	6	1	16828	49	PREX2
1.735e-02	-4.05	skin-in_situ_epithelial_neoplasm-actinic_keratosis	COSMIC cancer mutations	skin-in_situ_epithelial_neoplasm-actinic_keratosis	6	1	16828	49	FGFR3
1.735e-02	-4.05	skin-epidermal_nevus	COSMIC cancer mutations	skin-epidermal_nevus	6	1	16828	49	FGFR3
1.735e-02	-4.05	skin-face-other-seborrhoeic_keratosis	COSMIC cancer mutations	skin-face-other-seborrhoeic_keratosis	6	1	16828	49	FGFR3
1.735e-02	-4.05	collecting_duct_carcinoma	COSMIC cancer mutations	collecting_duct_carcinoma	6	1	16828	49	FGFR3
1.735e-02	-4.05	skin-flank-other-seborrhoeic_keratosis	COSMIC cancer mutations	skin-flank-other-seborrhoeic_keratosis	6	1	16828	49	FGFR3
1.735e-02	-4.05	skin-in_situ_epithelial_neoplasm-Bowen_disease	COSMIC cancer mutations	skin-in_situ_epithelial_neoplasm-Bowen_disease	6	1	16828	49	FGFR3
1.735e-02	-4.05	skin-head_neck-malignant_melanoma	COSMIC cancer mutations	skin-head_neck-malignant_melanoma	6	1	16828	49	PREX2
1.735e-02	-4.05	skin-lower_leg-epidermal_nevus	COSMIC cancer mutations	skin-lower_leg-epidermal_nevus	6	1	16828	49	FGFR3
1.735e-02	-4.05	skin-adnexal_tumour-trichoblastoma	COSMIC cancer mutations	skin-adnexal_tumour-trichoblastoma	6	1	16828	49	FGFR3
1.735e-02	-4.05	skin-benign_melanocytic_nevus-lentiginous_nevus	COSMIC cancer mutations	skin-benign_melanocytic_nevus-lentiginous_nevus	6	1	16828	49	FGFR3
1.735e-02	-4.05	kidney-carcinoma-collecting_duct_carcinoma	COSMIC cancer mutations	kidney-carcinoma-collecting_duct_carcinoma	6	1	16828	49	FGFR3
1.735e-02	-4.05	skin-lower_back-other-seborrhoeic_keratosis	COSMIC cancer mutations	skin-lower_back-other-seborrhoeic_keratosis	6	1	16828	49	FGFR3
1.735e-02	-4.05	skin-trunk-epidermal_nevus	COSMIC cancer mutations	skin-trunk-epidermal_nevus	6	1	16828	49	FGFR3
1.735e-02	-4.05	skin-abdomen-other-seborrhoeic_keratosis	COSMIC cancer mutations	skin-abdomen-other-seborrhoeic_keratosis	6	1	16828	49	FGFR3
1.735e-02	-4.05	skin-back-other-seborrhoeic_keratosis	COSMIC cancer mutations	skin-back-other-seborrhoeic_keratosis	6	1	16828	49	FGFR3
1.735e-02	-4.05	skin-head_neck-epidermal_nevus	COSMIC cancer mutations	skin-head_neck-epidermal_nevus	6	1	16828	49	FGFR3
1.738e-02	-4.05	regulation of behavior	biological process	GO:0050795	75	2	18204	49	PTGDS,APOE
1.738e-02	-4.05	amino acid biosynthetic process	biological process	GO:0008652	75	2	18204	49	SLC1A3,GLUL
1.751e-02	-4.05	face	COSMIC cancer mutations	face	2139	12	16828	49	ZNRF3,RORA,PCDH9,FGFR3,TRPS1,HEPACAM,MSI2,GPC5,GPM6A,LSAMP,PTPRZ1,PREX2
1.759e-02	-4.04	NUCB2 (nucleobindin 2)	protein interactions	4925	79	2	19454	50	CLU,GLUL
1.759e-02	-4.04	PRDM1 (PR/SET domain 1)	protein interactions	639	79	2	19454	50	TRPS1,NFIA
1.786e-02	-4.03	Pum2 (pumilio RNA-binding family member 2)	protein interactions	80913	7	1	19454	50	QKI
1.786e-02	-4.03	ZBTB45 (zinc finger and BTB domain containing 45)	protein interactions	84878	7	1	19454	50	ZBTB20
1.786e-02	-4.03	Uhmk1 (U2AF homology motif (UHM) kinase 1)	protein interactions	16589	7	1	19454	50	BMPR1B
1.786e-02	-4.03	Smad7 (SMAD family member 7)	protein interactions	17131	7	1	19454	50	BMPR1B
1.786e-02	-4.03	Ahcyl1 (S-adenosylhomocysteine hydrolase-like 1)	protein interactions	229709	7	1	19454	50	AHCYL2
1.786e-02	-4.03	RGMB (repulsive guidance molecule BMP co-receptor b)	protein interactions	285704	7	1	19454	50	BMPR1B
1.786e-02	-4.03	SASH3 (SAM and SH3 domain containing 3)	protein interactions	54440	7	1	19454	50	BMPR1B
1.786e-02	-4.03	Smurf1 (SMAD specific E3 ubiquitin protein ligase 1)	protein interactions	75788	7	1	19454	50	GLIS3
1.786e-02	-4.03	SLC16A5 (solute carrier family 16 member 5)	protein interactions	9121	7	1	19454	50	PTPRZ1
1.786e-02	-4.03	ABCC12 (ATP binding cassette subfamily C member 12)	protein interactions	94160	7	1	19454	50	NPAS3
1.786e-02	-4.03	CYP4F8 (cytochrome P450 family 4 subfamily F member 8)	protein interactions	11283	7	1	19454	50	CLU
1.786e-02	-4.03	C8B (complement C8 beta chain)	protein interactions	732	7	1	19454	50	CLU
1.786e-02	-4.03	FGF5 (fibroblast growth factor 5)	protein interactions	2250	7	1	19454	50	FGFR3
1.786e-02	-4.03	SOAT2 (sterol O-acyltransferase 2)	protein interactions	8435	7	1	19454	50	CLU
1.786e-02	-4.03	C7 (complement C7)	protein interactions	730	7	1	19454	50	CLU
1.786e-02	-4.03	Fbxo3 (F-box protein 3)	protein interactions	57443	7	1	19454	50	BMPR1B
1.801e-02	-4.02	MAP2 (microtubule associated protein 2)	protein interactions	4133	80	2	19454	50	APOE,GPM6A
1.804e-02	-4.01	phosphatidic acid transfer activity	molecular function	GO:1990050	7	1	18094	47	PITPNC1
1.804e-02	-4.01	P-type sodium transporter activity	molecular function	GO:0008554	7	1	18094	47	ATP1A2
1.804e-02	-4.01	P-type sodium:potassium-exchanging transporter activity	molecular function	GO:0005391	7	1	18094	47	ATP1A2
1.811e-02	-4.01	Glutamine synthetase/guanido kinase, catalytic domain	gene3d domains	3.30.590.10	6	1	14470	44	GLUL
1.811e-02	-4.01	IP3 receptor type 1 binding core, RIH domain	gene3d domains	1.25.10.30	6	1	14470	44	RYR3
1.827e-02	-4.00	BMP signaling pathway	biological process	GO:0030509	77	2	18204	49	BMPR1B,NFIA
1.827e-02	-4.00	regulation of synaptic transmission, glutamatergic	biological process	GO:0051966	77	2	18204	49	ATP1A2,NRXN1
1.843e-02	-3.99	SOX17 (SRY-box transcription factor 17)	protein interactions	64321	81	2	19454	50	NFIA,TRPS1
1.869e-02	-3.98	regulation of 3'-UTR-mediated mRNA stabilization	biological process	GO:1905868	7	1	18204	49	QKI
1.869e-02	-3.98	high-density lipoprotein particle clearance	biological process	GO:0034384	7	1	18204	49	APOE
1.869e-02	-3.98	negative regulation of Arp2/3 complex-mediated actin nucleation	biological process	GO:0034316	7	1	18204	49	CTNNA2
1.869e-02	-3.98	glial cell fate specification	biological process	GO:0021780	7	1	18204	49	NFIA
1.869e-02	-3.98	negative regulation of non-canonical Wnt signaling pathway	biological process	GO:2000051	7	1	18204	49	ZNRF3
1.869e-02	-3.98	regulation of oligodendrocyte progenitor proliferation	biological process	GO:0070445	7	1	18204	49	PTPRZ1
1.869e-02	-3.98	regulation of male germ cell proliferation	biological process	GO:2000254	7	1	18204	49	PTGDS
1.869e-02	-3.98	positive regulation of transcription of Notch receptor target	biological process	GO:0007221	7	1	18204	49	MAML2
1.869e-02	-3.98	cellular response to magnesium ion	biological process	GO:0071286	7	1	18204	49	RYR3
1.869e-02	-3.98	observational learning	biological process	GO:0098597	7	1	18204	49	NRXN1
1.869e-02	-3.98	positive regulation of receptor catabolic process	biological process	GO:2000646	7	1	18204	49	APOE
1.869e-02	-3.98	chaperone-mediated autophagy	biological process	GO:0061684	7	1	18204	49	CLU
1.869e-02	-3.98	very-low-density lipoprotein particle remodeling	biological process	GO:0034372	7	1	18204	49	APOE
1.869e-02	-3.98	S-adenosylmethionine cycle	biological process	GO:0033353	7	1	18204	49	AHCYL2
1.872e-02	-3.98	positive regulation of carbohydrate metabolic process	biological process	GO:0045913	78	2	18204	49	ZBTB20,SLC4A4
1.872e-02	-3.98	dicarboxylic acid transport	biological process	GO:0006835	78	2	18204	49	SLC1A3,SLC1A2
1.875e-02	-3.98	SPARC/Testican_Ca-bd-dom	interpro domains	IPR019577	7	1	18521	50	SPARCL1
1.875e-02	-3.98	Alpha-catenin/vinculin-like_sf	interpro domains	IPR036723	7	1	18521	50	CTNNA2
1.875e-02	-3.98	GS_dom	interpro domains	IPR003605	7	1	18521	50	BMPR1B
1.878e-02	-3.97	transmembrane receptor protein kinase activity	molecular function	GO:0019199	81	2	18094	47	BMPR1B,FGFR3
1.882e-02	-3.97	HAD-like_sf	interpro domains	IPR036412	78	2	18521	50	ATP1A2,ATP13A4
1.897e-02	-3.96	human chr9p24.2	chromosome location	human chr9p24.2	10	1	26134	50	GLIS3
1.899e-02	-3.96	NAHCO3TRSPRT	prints domains	PR01232	5	1	5227	20	SLC4A4
1.899e-02	-3.96	PITRANSFER	prints domains	PR00391	5	1	5227	20	PITPNC1
1.917e-02	-3.95	regulation of glial cell differentiation	biological process	GO:0045685	79	2	18204	49	QKI,PTPRZ1
1.922e-02	-3.95	prostate	COSMIC cancer mutations	prostate	13883	46	16828	49	HEPACAM,TRPS1,HIF3A,FGFR3,ATP13A4,NTM,CDH20,NHSL1,PITPNC1,AHCYL2,SLC4A4,CLU,ATP1A2,PAMR1,LSAMP,DTNA,MSI2,FBXL7,SOX5,SPARCL1,PON2,COL5A3,GLIS3,NRXN1,PCDH9,ZNRF3,MAML2,SLC1A3,PREX2,PARD3B,APOE,CPE,GPM6A,GPC5,ZBTB20,NFIA,RORA,HPSE2,RYR3,TNIK,QKI,SLC1A2,NPAS3,PTPRZ1,NKAIN3,BMPR1B
1.930e-02	-3.95	PAX2 (paired box 2)	protein interactions	5076	83	2	19454	50	TRPS1,NFIA
1.930e-02	-3.95	TM2D3 (TM2 domain containing 3)	protein interactions	80213	83	2	19454	50	FGFR3,PON2
1.930e-02	-3.95	SYT1 (synaptotagmin 1)	protein interactions	6857	83	2	19454	50	GPM6A,NRXN1
1.930e-02	-3.95	DNM3 (dynamin 3)	protein interactions	26052	83	2	19454	50	FGFR3,GPM6A
1.951e-02	-3.94	SPARC_Ca_bdg	pfam domains	PF10591	7	1	17795	50	SPARCL1
1.951e-02	-3.94	TGF_beta_GS	pfam domains	PF08515	7	1	17795	50	BMPR1B
1.989e-02	-3.92	Neuronal System	REACTOME pathways	R-HSA-112316	349	4	10285	31	GLUL,SLC1A2,NRXN1,SLC1A3
2.008e-02	-3.91	KLF3 (KLF transcription factor 3)	protein interactions	51274	225	3	19454	50	NFIA,SOX5,TRPS1
2.009e-02	-3.91	adult locomotory behavior	biological process	GO:0008344	81	2	18204	49	ATP1A2,PREX2
2.009e-02	-3.91	regulation of amide metabolic process	biological process	GO:0034248	81	2	18204	49	CLU,APOE
2.018e-02	-3.90	CCND3 (cyclin D3)	protein interactions	896	85	2	19454	50	QKI,CLU
2.020e-02	-3.90	SOX2 (SRY-box transcription factor 2)	protein interactions	6657	1342	8	19454	50	TRPS1,LSAMP,QKI,MSI2,NFIA,GLIS3,CLU,SOX5
2.021e-02	-3.90	trichilemmoma	COSMIC cancer mutations	trichilemmoma	7	1	16828	49	FGFR3
2.021e-02	-3.90	urinary_tract-carcinoma-transitional_cell_carcinoma	COSMIC cancer mutations	urinary_tract-carcinoma-transitional_cell_carcinoma	7	1	16828	49	FGFR3
2.021e-02	-3.90	skin-other-nevus_sebaceous	COSMIC cancer mutations	skin-other-nevus_sebaceous	7	1	16828	49	FGFR3
2.021e-02	-3.90	skin-adnexal_tumour-trichilemmoma	COSMIC cancer mutations	skin-adnexal_tumour-trichilemmoma	7	1	16828	49	FGFR3
2.021e-02	-3.90	skin-shoulder-other-seborrhoeic_keratosis	COSMIC cancer mutations	skin-shoulder-other-seborrhoeic_keratosis	7	1	16828	49	FGFR3
2.021e-02	-3.90	skin-upper_leg-malignant_melanoma-nodular	COSMIC cancer mutations	skin-upper_leg-malignant_melanoma-nodular	7	1	16828	49	PREX2
2.021e-02	-3.90	skin-face-adnexal_tumour-malignant_adnexal_tumour	COSMIC cancer mutations	skin-face-adnexal_tumour-malignant_adnexal_tumour	7	1	16828	49	FGFR3
2.021e-02	-3.90	nevus_sebaceous	COSMIC cancer mutations	nevus_sebaceous	7	1	16828	49	FGFR3
2.021e-02	-3.90	skin-neck-other-seborrhoeic_keratosis	COSMIC cancer mutations	skin-neck-other-seborrhoeic_keratosis	7	1	16828	49	FGFR3
2.021e-02	-3.90	skin-face-malignant_melanoma-nodular	COSMIC cancer mutations	skin-face-malignant_melanoma-nodular	7	1	16828	49	PREX2
2.021e-02	-3.90	skin-benign_melanocytic_nevus-intradermal	COSMIC cancer mutations	skin-benign_melanocytic_nevus-intradermal	7	1	16828	49	FGFR3
2.021e-02	-3.90	skin-benign_melanocytic_nevus-compound	COSMIC cancer mutations	skin-benign_melanocytic_nevus-compound	7	1	16828	49	FGFR3
2.021e-02	-3.90	skin-chest-other-seborrhoeic_keratosis	COSMIC cancer mutations	skin-chest-other-seborrhoeic_keratosis	7	1	16828	49	FGFR3
2.034e-02	-3.90	HFE-transferrin receptor complex	cellular component	GO:1990712	8	1	19108	49	BMPR1B
2.034e-02	-3.90	spherical high-density lipoprotein particle	cellular component	GO:0034366	8	1	19108	49	CLU
2.038e-02	-3.89	CCK (cholecystokinin)	protein interactions	885	8	1	19454	50	CPE
2.038e-02	-3.89	Chmp2a (charged multivesicular body protein 2A)	protein interactions	68953	8	1	19454	50	CLU
2.038e-02	-3.89	PTGER1 (prostaglandin E receptor 1)	protein interactions	5731	8	1	19454	50	PTGDS
2.038e-02	-3.89	DEPP1 (DEPP autophagy regulator 1)	protein interactions	11067	8	1	19454	50	QKI
2.038e-02	-3.89	BMP15 (bone morphogenetic protein 15)	protein interactions	9210	8	1	19454	50	BMPR1B
2.038e-02	-3.89	LHB (luteinizing hormone subunit beta)	protein interactions	3972	8	1	19454	50	NTM
2.038e-02	-3.89	Rasd2 (RASD family, member 2)	protein interactions	75141	8	1	19454	50	BMPR1B
2.038e-02	-3.89	Rps27a (ribosomal protein S27A)	protein interactions	78294	8	1	19454	50	BMPR1B
2.051e-02	-3.89	GLYPICAN	prosite domains	PS01207	6	1	12186	42	GPC5
2.059e-02	-3.88	positive regulation of cellular catabolic process	biological process	GO:0031331	217	3	18204	49	SLC4A4,APOE,ZBTB20
2.060e-02	-3.88	BMP receptor activity	molecular function	GO:0098821	8	1	18094	47	BMPR1B
2.060e-02	-3.88	P-type potassium transmembrane transporter activity	molecular function	GO:0008556	8	1	18094	47	ATP1A2
2.060e-02	-3.88	sodium ion binding	molecular function	GO:0031402	8	1	18094	47	ATP1A2
2.060e-02	-3.88	glutamate binding	molecular function	GO:0016595	8	1	18094	47	SLC1A3
2.063e-02	-3.88	EGLN1 (egl-9 family hypoxia inducible factor 1)	protein interactions	54583	86	2	19454	50	FGFR3,HIF3A
2.084e-02	-3.87	dendrite	cellular component	GO:0030425	620	5	19108	49	GPM6A,APOE,CLU,BMPR1B,ATP1A2
2.091e-02	-3.87	FGFR3b ligand binding and activation	REACTOME pathways	R-HSA-190371	7	1	10285	31	FGFR3
2.108e-02	-3.86	NHLH1 (nescient helix-loop-helix 1)	protein interactions	4807	87	2	19454	50	TRPS1,NFIA
2.108e-02	-3.86	Kctd5 (potassium channel tetramerisation domain containing 5)	protein interactions	69259	87	2	19454	50	TRPS1,SLC1A3
2.108e-02	-3.86	MIR141 (microRNA 141)	protein interactions	406933	87	2	19454	50	MSI2,QKI
2.108e-02	-3.86	ZNF608 (zinc finger protein 608)	protein interactions	57507	87	2	19454	50	NFIA,SOX5
2.110e-02	-3.86	dendritic tree	cellular component	GO:0097447	622	5	19108	49	CLU,APOE,GPM6A,ATP1A2,BMPR1B
2.123e-02	-3.85	kidney-carcinoma-clear_cell_renal_cell_carcinoma	COSMIC cancer mutations	kidney-carcinoma-clear_cell_renal_cell_carcinoma	13924	46	16828	49	GLIS3,NRXN1,PCDH9,PTGDS,ZNRF3,MAML2,PREX2,SLC1A3,PARD3B,APOE,CPE,GPM6A,GPC5,ZBTB20,NFIA,RORA,TNIK,HPSE2,RYR3,QKI,SLC1A2,NPAS3,PTPRZ1,NKAIN3,GLUL,BMPR1B,TRPS1,HEPACAM,HIF3A,FGFR3,ATP13A4,CDH20,NHSL1,PITPNC1,SLC4A4,AHCYL2,ATP1A2,CLU,PAMR1,LSAMP,DTNA,MSI2,FBXL7,SOX5,SPARCL1,COL5A3
2.123e-02	-3.85	clear_cell_renal_cell_carcinoma	COSMIC cancer mutations	clear_cell_renal_cell_carcinoma	13924	46	16828	49	CPE,APOE,PARD3B,PREX2,SLC1A3,MAML2,PTGDS,ZNRF3,PCDH9,NRXN1,GLIS3,BMPR1B,GLUL,NKAIN3,PTPRZ1,NPAS3,SLC1A2,QKI,RYR3,HPSE2,TNIK,RORA,NFIA,ZBTB20,GPC5,GPM6A,LSAMP,PAMR1,CLU,ATP1A2,SLC4A4,AHCYL2,PITPNC1,NHSL1,CDH20,ATP13A4,FGFR3,HIF3A,HEPACAM,TRPS1,COL5A3,SPARCL1,SOX5,FBXL7,MSI2,DTNA
2.125e-02	-3.85	HAD superfamily/HAD-like	gene3d domains	3.40.50.1000	74	2	14470	44	ATP13A4,ATP1A2
2.125e-02	-3.85	acute_lymphoblastic_leukaemia	COSMIC cancer mutations	acute_lymphoblastic_leukaemia	2197	12	16828	49	FGFR3,SOX5,TNIK,DTNA,NFIA,TRPS1,SLC4A4,PARD3B,ATP1A2,BMPR1B,PTPRZ1,PREX2
2.126e-02	-3.85	femur	COSMIC cancer mutations	femur	1197	8	16828	49	PON2,GPC5,PTPRZ1,SLC4A4,PCDH9,GLUL,HPSE2,RYR3
2.127e-02	-3.85	ConA-like_dom_sf	interpro domains	IPR013320	219	3	18521	50	RYR3,NRXN1,COL5A3
2.134e-02	-3.85	insulin processing	biological process	GO:0030070	8	1	18204	49	CPE
2.134e-02	-3.85	cell proliferation in hindbrain	biological process	GO:0021534	8	1	18204	49	RORA
2.134e-02	-3.85	cell proliferation in external granule layer	biological process	GO:0021924	8	1	18204	49	RORA
2.134e-02	-3.85	regulation of Cdc42 protein signal transduction	biological process	GO:0032489	8	1	18204	49	APOE
2.134e-02	-3.85	triglyceride-rich lipoprotein particle remodeling	biological process	GO:0034370	8	1	18204	49	APOE
2.134e-02	-3.85	regulation of synapse structural plasticity	biological process	GO:0051823	8	1	18204	49	CTNNA2
2.134e-02	-3.85	gamma-aminobutyric acid metabolic process	biological process	GO:0009448	8	1	18204	49	SLC1A3
2.134e-02	-3.85	regulation of germ cell proliferation	biological process	GO:1905936	8	1	18204	49	PTGDS
2.134e-02	-3.85	regulation of L-glutamate import across plasma membrane	biological process	GO:0002036	8	1	18204	49	ATP1A2
2.134e-02	-3.85	positive regulation of amyloid-beta clearance	biological process	GO:1900223	8	1	18204	49	APOE
2.134e-02	-3.85	positive regulation of CoA-transferase activity	biological process	GO:1905920	8	1	18204	49	APOE
2.134e-02	-3.85	glutamate catabolic process	biological process	GO:0006538	8	1	18204	49	GLUL
2.134e-02	-3.85	cerebellar granule cell precursor proliferation	biological process	GO:0021930	8	1	18204	49	RORA
2.134e-02	-3.85	response to mechanical stimulus	biological process	GO:0009612	220	3	18204	49	ATP1A2,SLC1A3,NRXN1
2.140e-02	-3.84	Gln_synth/guanido_kin_cat_dom	interpro domains	IPR014746	8	1	18521	50	GLUL
2.144e-02	-3.84	Bile secretion	KEGG pathways	ko04976	71	2	7161	23	SLC4A4,ATP1A2
2.144e-02	-3.84	Bile secretion	KEGG pathways	hsa04976	71	2	7161	23	SLC4A4,ATP1A2
2.151e-02	-3.84	L-amino acid transport	biological process	GO:0015807	84	2	18204	49	SLC1A3,SLC1A2
2.151e-02	-3.84	regulation of sodium ion transport	biological process	GO:0002028	84	2	18204	49	NKAIN3,ATP1A2
2.153e-02	-3.84	RAP2A (RAP2A, member of RAS oncogene family)	protein interactions	5911	88	2	19454	50	BMPR1B,TNIK
2.153e-02	-3.84	Ig_sub	interpro domains	IPR003599	394	4	18521	50	FGFR3,HEPACAM,NTM,LSAMP
2.175e-02	-3.83	CTSB (cathepsin B)	protein interactions	1508	232	3	19454	50	CST3,APOE,MSI2
2.199e-02	-3.82	oligodendrocyte differentiation	biological process	GO:0048709	85	2	18204	49	PTPRZ1,CLU
2.199e-02	-3.82	PLEKHA2 (pleckstrin homology domain containing A2)	protein interactions	59339	89	2	19454	50	AHCYL2,DTNA
2.199e-02	-3.82	SOX10 (SRY-box transcription factor 10)	protein interactions	6663	89	2	19454	50	TRPS1,NFIA
2.201e-02	-3.82	organic anion transport	biological process	GO:0015711	398	4	18204	49	SLC1A3,SLC4A4,APOE,SLC1A2
2.221e-02	-3.81	DNA-binding transcription factor activity, RNA polymerase II-specific	molecular function	GO:0000981	1355	8	18094	47	HIF3A,GLIS3,NFIA,NPAS3,TRPS1,SOX5,ZBTB20,RORA
2.224e-02	-3.81	HMG20A (high mobility group 20A)	protein interactions	10363	234	3	19454	50	NFIA,DTNA,SOX5
2.243e-02	-3.80	follicular_lymphoma	COSMIC cancer mutations	follicular_lymphoma	1209	8	16828	49	LSAMP,SOX5,TNIK,HPSE2,RORA,PCDH9,NKAIN3,GPC5
2.262e-02	-3.79	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-follicular_lymphoma	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-follicular_lymphoma	981	7	16828	49	NKAIN3,GPC5,LSAMP,RORA,PCDH9,SOX5,HPSE2
2.272e-02	-3.78	human chr6q26	chromosome location	human chr6q26	12	1	26134	50	QKI
2.274e-02	-3.78	CTSL (cathepsin L)	protein interactions	1514	236	3	19454	50	CLU,PON2,CST3
2.275e-02	-3.78	ACTIVIN2R	prints domains	PR00653	6	1	5227	20	BMPR1B
2.290e-02	-3.78	KLB (klotho beta)	protein interactions	152831	9	1	19454	50	FGFR3
2.290e-02	-3.78	Ywhag (tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide)	protein interactions	22628	9	1	19454	50	QKI
2.290e-02	-3.78	Tyw3 (tRNA-yW synthesizing protein 3 homolog (S. cerevisiae))	protein interactions	209584	9	1	19454	50	CTNNA2
2.290e-02	-3.78	LINC02582 (long intergenic non-protein coding RNA 2582)	protein interactions	100505817	9	1	19454	50	APOE
2.290e-02	-3.78	VEPH1 (ventricular zone expressed PH domain containing 1)	protein interactions	79674	9	1	19454	50	BMPR1B
2.290e-02	-3.78	CACNA2D3 (calcium voltage-gated channel auxiliary subunit alpha2delta 3)	protein interactions	55799	9	1	19454	50	APOE
2.290e-02	-3.78	GUSBP1 (GUSB pseudogene 1)	protein interactions	728411	9	1	19454	50	FGFR3
2.292e-02	-3.78	FOXI1 (forkhead box I1)	protein interactions	2299	91	2	19454	50	TRPS1,NFIA
2.292e-02	-3.78	DGUOK (deoxyguanosine kinase)	protein interactions	1716	91	2	19454	50	NTM,GPM6A
2.306e-02	-3.77	cervix-in_situ_neoplasm-cervical_intraepithelial_neoplasia_Grade_I	COSMIC cancer mutations	cervix-in_situ_neoplasm-cervical_intraepithelial_neoplasia_Grade_I	8	1	16828	49	FGFR3
2.306e-02	-3.77	junctional	COSMIC cancer mutations	junctional	8	1	16828	49	FGFR3
2.306e-02	-3.77	actinic_keratosis	COSMIC cancer mutations	actinic_keratosis	8	1	16828	49	FGFR3
2.306e-02	-3.77	central_nervous_system-chiasm-glioma-astrocytoma_Grade_I	COSMIC cancer mutations	central_nervous_system-chiasm-glioma-astrocytoma_Grade_I	8	1	16828	49	QKI
2.306e-02	-3.77	urinary_tract-ureter-carcinoma-transitional_cell_carcinoma	COSMIC cancer mutations	urinary_tract-ureter-carcinoma-transitional_cell_carcinoma	8	1	16828	49	FGFR3
2.306e-02	-3.77	cervical_intraepithelial_neoplasia_Grade_I	COSMIC cancer mutations	cervical_intraepithelial_neoplasia_Grade_I	8	1	16828	49	FGFR3
2.306e-02	-3.77	skin-chest-malignant_melanoma-nodular	COSMIC cancer mutations	skin-chest-malignant_melanoma-nodular	8	1	16828	49	PREX2
2.306e-02	-3.77	trichoblastoma	COSMIC cancer mutations	trichoblastoma	8	1	16828	49	FGFR3
2.320e-02	-3.76	Bile Acid Indirect Signalling Pathway	SMPDB pathways	SMP0086851	8	1	1369	4	FGFR3
2.323e-02	-3.76	lipid binding	molecular function	GO:0008289	861	6	18094	47	RORA,PTGDS,APOE,ATP1A2,PITPNC1,PARD3B
2.324e-02	-3.76	LCOR (ligand dependent nuclear receptor corepressor)	protein interactions	84458	238	3	19454	50	SPARCL1,GLUL,CLU
2.325e-02	-3.76	forearm	COSMIC cancer mutations	forearm	81	2	16828	49	PREX2,FGFR3
2.339e-02	-3.76	FNTA (farnesyltransferase, CAAX box, subunit alpha)	protein interactions	2339	92	2	19454	50	TNIK,FGFR3
2.339e-02	-3.76	SOX9 (SRY-box transcription factor 9)	protein interactions	6662	92	2	19454	50	NFIA,TRPS1
2.339e-02	-3.76	RLN1 (relaxin 1)	protein interactions	6013	92	2	19454	50	CPE,PON2
2.339e-02	-3.76	POTEI (POTE ankyrin domain family member I)	protein interactions	653269	92	2	19454	50	FGFR3,DTNA
2.341e-02	-3.75	skeletal system morphogenesis	biological process	GO:0048705	228	3	18204	49	BMPR1B,FGFR3,SOX5
2.351e-02	-3.75	transmembrane transporter activity	molecular function	GO:0022857	1110	7	18094	47	SLC1A3,RYR3,ATP1A2,GPM6A,ATP13A4,SLC4A4,SLC1A2
2.375e-02	-3.74	ATP6V1A (ATPase H+ transporting V1 subunit A)	protein interactions	523	240	3	19454	50	PON2,ATP1A2,APOE
2.387e-02	-3.74	Release of Hh-Np from the secreting cell	REACTOME pathways	R-HSA-5362798	8	1	10285	31	GPC5
2.387e-02	-3.74	MIR19B2 (microRNA 19b-2)	protein interactions	406981	93	2	19454	50	QKI,MSI2
2.387e-02	-3.74	RBM23 (RNA binding motif protein 23)	protein interactions	55147	93	2	19454	50	QKI,AHCYL2
2.387e-02	-3.74	DMRTB1 (DMRT like family B with proline rich C-terminal 1)	protein interactions	63948	93	2	19454	50	QKI,MSI2
2.387e-02	-3.74	TEX11 (testis expressed 11)	protein interactions	56159	93	2	19454	50	QKI,SOX5
2.388e-02	-3.73	hand	COSMIC cancer mutations	hand	566	5	16828	49	COL5A3,HIF3A,FGFR3,SLC4A4,PREX2
2.388e-02	-3.73	GS	prosite domains	PS51256	7	1	12186	42	BMPR1B
2.395e-02	-3.73	positive regulation of lipid biosynthetic process	biological process	GO:0046889	89	2	18204	49	APOE,ZBTB20
2.397e-02	-3.73	polyamine transmembrane transport	biological process	GO:1902047	9	1	18204	49	ATP13A4
2.397e-02	-3.73	regulation of protein localization to nucleolus	biological process	GO:1904749	9	1	18204	49	GLUL
2.397e-02	-3.73	negative regulation of actin nucleation	biological process	GO:0051126	9	1	18204	49	CTNNA2
2.397e-02	-3.73	sterol catabolic process	biological process	GO:0016127	9	1	18204	49	APOE
2.397e-02	-3.73	hindbrain radial glia guided cell migration	biological process	GO:0021932	9	1	18204	49	CTNNA2
2.397e-02	-3.73	cyclooxygenase pathway	biological process	GO:0019371	9	1	18204	49	PTGDS
2.397e-02	-3.73	positive regulation of synapse maturation	biological process	GO:0090129	9	1	18204	49	NRXN1
2.397e-02	-3.73	cholesterol catabolic process	biological process	GO:0006707	9	1	18204	49	APOE
2.397e-02	-3.73	negative regulation of striated muscle contraction	biological process	GO:0045988	9	1	18204	49	ATP1A2
2.397e-02	-3.73	macrophage proliferation	biological process	GO:0061517	9	1	18204	49	CLU
2.397e-02	-3.73	release of sequestered calcium ion into cytosol by sarcoplasmic reticulum	biological process	GO:0014808	9	1	18204	49	RYR3
2.397e-02	-3.73	microglial cell proliferation	biological process	GO:0061518	9	1	18204	49	CLU
2.404e-02	-3.73	Fol_N	interpro domains	IPR003645	9	1	18521	50	SPARCL1
2.404e-02	-3.73	Activin_recp	interpro domains	IPR000472	9	1	18521	50	BMPR1B
2.404e-02	-3.73	Prot_inh_cystat_CS	interpro domains	IPR018073	9	1	18521	50	CST3
2.404e-02	-3.73	Band3_cytoplasmic_dom	interpro domains	IPR013769	9	1	18521	50	SLC4A4
2.411e-02	-3.73	intracellular signaling cassette	biological process	GO:0141124	837	6	18204	49	APOE,ATP1A2,FGFR3,RYR3,TNIK,PREX2
2.422e-02	-3.72	calcium ion homeostasis	biological process	GO:0055074	231	3	18204	49	APOE,RYR3,ATP13A4
2.433e-02	-3.72	Endochondral Ossification	WikiPathways	WP474	65	2	5310	20	SOX5,FGFR3
2.435e-02	-3.72	FOXP4 (forkhead box P4)	protein interactions	116113	94	2	19454	50	NFIA,SOX5
2.435e-02	-3.72	QSER1 (glutamine and serine rich 1)	protein interactions	79832	94	2	19454	50	NFIA,SOX5
2.446e-02	-3.71	regulation of purine nucleotide metabolic process	biological process	GO:1900542	90	2	18204	49	ZBTB20,SLC4A4
2.446e-02	-3.71	lipoprotein biosynthetic process	biological process	GO:0042158	90	2	18204	49	GLUL,APOE
2.448e-02	-3.71	Ion channel transport	REACTOME pathways	R-HSA-983712	209	3	10285	31	RYR3,ATP1A2,ATP13A4
2.453e-02	-3.71	Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour	COSMIC cancer mutations	Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour	7434	29	16828	49	SLC1A3,PREX2,PARD3B,ATP1A2,SLC4A4,PAMR1,NRXN1,GLIS3,HIF3A,TRPS1,MAML2,PTGDS,ATP13A4,FGFR3,PTPRZ1,NPAS3,PON2,NKAIN3,GLUL,COL5A3,ZBTB20,DTNA,CST3,SOX5,TNIK,RYR3,RORA,SPARCL1,QKI
2.459e-02	-3.71	human chr5p15.1	chromosome location	human chr5p15.1	13	1	26134	50	FBXL7
2.476e-02	-3.70	inorganic cation transmembrane transport	biological process	GO:0098662	618	5	18204	49	RYR3,SLC1A3,GPM6A,ATP1A2,SLC4A4
2.487e-02	-3.69	response to organic cyclic compound	biological process	GO:0014070	843	6	18204	49	ATP1A2,RYR3,RORA,SLC1A2,PTGDS,SLC1A3
2.496e-02	-3.69	RNA polymerase II transcription regulatory region sequence-specific DNA binding	molecular function	GO:0000977	1385	8	18094	47	TRPS1,SOX5,NPAS3,NFIA,HIF3A,GLIS3,RORA,ZBTB20
2.496e-02	-3.69	cellular response to BMP stimulus	biological process	GO:0071773	91	2	18204	49	NFIA,BMPR1B
2.496e-02	-3.69	regulation of nucleotide metabolic process	biological process	GO:0006140	91	2	18204	49	SLC4A4,ZBTB20
2.496e-02	-3.69	response to BMP	biological process	GO:0071772	91	2	18204	49	BMPR1B,NFIA
2.501e-02	-3.69	Band_3_cyto	pfam domains	PF07565	9	1	17795	50	SLC4A4
2.501e-02	-3.69	Activin_recp	pfam domains	PF01064	9	1	17795	50	BMPR1B
2.536e-02	-3.67	perineuronal net	cellular component	GO:0072534	10	1	19108	49	PTPRZ1
2.537e-02	-3.67	positive regulation of catabolic process	biological process	GO:0009896	622	5	18204	49	ZBTB20,QKI,APOE,CLU,SLC4A4
2.541e-02	-3.67	CALB2 (calbindin 2)	protein interactions	794	10	1	19454	50	GPM6A
2.541e-02	-3.67	P2rx7 (purinergic receptor P2X 7)	protein interactions	29665	10	1	19454	50	PTPRZ1
2.541e-02	-3.67	ALKAL2 (ALK and LTK ligand 2)	protein interactions	285016	10	1	19454	50	PON2
2.541e-02	-3.67	SLC8A2 (solute carrier family 8 member A2)	protein interactions	6543	10	1	19454	50	GPM6A
2.541e-02	-3.67	Hsp90aa1 (heat shock protein 90, alpha (cytosolic), class A member 1)	protein interactions	15519	10	1	19454	50	QKI
2.541e-02	-3.67	Mrpl13 (mitochondrial ribosomal protein L13)	protein interactions	68537	10	1	19454	50	QKI
2.541e-02	-3.67	Smurf2 (SMAD specific E3 ubiquitin protein ligase 2)	protein interactions	66313	10	1	19454	50	GLIS3
2.541e-02	-3.67	GSG1 (germ cell associated 1)	protein interactions	83445	10	1	19454	50	PITPNC1
2.541e-02	-3.67	SERPINB11 (serpin family B member 11)	protein interactions	89778	10	1	19454	50	CPE
2.568e-02	-3.66	spindle	COSMIC cancer mutations	spindle	386	4	16828	49	PCDH9,FGFR3,PREX2,CPE
2.568e-02	-3.66	phosphatidylinositol transfer activity	molecular function	GO:0008526	10	1	18094	47	PITPNC1
2.568e-02	-3.66	polyamine transmembrane transporter activity	molecular function	GO:0015203	10	1	18094	47	ATP13A4
2.580e-02	-3.66	ATPase-coupled transmembrane transporter activity	molecular function	GO:0042626	96	2	18094	47	ATP13A4,ATP1A2
2.585e-02	-3.66	NCOR2 (nuclear receptor corepressor 2)	protein interactions	9612	248	3	19454	50	SOX5,TNIK,NFIA
2.590e-02	-3.65	upper_aerodigestive_tract-pharynx-carcinoma-squamous_cell_carcinoma	COSMIC cancer mutations	upper_aerodigestive_tract-pharynx-carcinoma-squamous_cell_carcinoma	1485	9	16828	49	GPC5,PTPRZ1,PREX2,DTNA,NPAS3,RYR3,PARD3B,FGFR3,PCDH9
2.591e-02	-3.65	skin-other-seborrhoeic_keratosis	COSMIC cancer mutations	skin-other-seborrhoeic_keratosis	9	1	16828	49	FGFR3
2.591e-02	-3.65	epidermal_nevus	COSMIC cancer mutations	epidermal_nevus	9	1	16828	49	FGFR3
2.591e-02	-3.65	skin-chest-malignant_melanoma-superficial_spreading	COSMIC cancer mutations	skin-chest-malignant_melanoma-superficial_spreading	9	1	16828	49	PREX2
2.591e-02	-3.65	ovary-low_malignant_potential_(borderline)_tumour-Brenner_tumour	COSMIC cancer mutations	ovary-low_malignant_potential_(borderline)_tumour-Brenner_tumour	9	1	16828	49	FGFR3
2.591e-02	-3.65	compound	COSMIC cancer mutations	compound	9	1	16828	49	FGFR3
2.591e-02	-3.65	skin-upper_leg-malignant_melanoma-superficial_spreading	COSMIC cancer mutations	skin-upper_leg-malignant_melanoma-superficial_spreading	9	1	16828	49	PREX2
2.591e-02	-3.65	skin-benign_melanocytic_nevus-congenital	COSMIC cancer mutations	skin-benign_melanocytic_nevus-congenital	9	1	16828	49	FGFR3
2.591e-02	-3.65	Bowen_disease	COSMIC cancer mutations	Bowen_disease	9	1	16828	49	FGFR3
2.591e-02	-3.65	in_situ_epithelial_neoplasm	COSMIC cancer mutations	in_situ_epithelial_neoplasm	9	1	16828	49	FGFR3
2.616e-02	-3.64	muscle contraction	biological process	GO:0006936	238	3	18204	49	RYR3,DTNA,ATP1A2
2.618e-02	-3.64	axon development	biological process	GO:0061564	420	4	18204	49	NRXN1,PTPRZ1,CTNNA2,BMPR1B
2.631e-02	-3.64	MED27 (mediator complex subunit 27)	protein interactions	9442	98	2	19454	50	SOX5,QKI
2.631e-02	-3.64	DNAAF2 (dynein axonemal assembly factor 2)	protein interactions	55172	98	2	19454	50	LSAMP,GPM6A
2.646e-02	-3.63	human chr2p16.3	chromosome location	human chr2p16.3	14	1	26134	50	NRXN1
2.660e-02	-3.63	nitric oxide-cGMP-mediated signaling	biological process	GO:0038060	10	1	18204	49	APOE
2.660e-02	-3.63	release of sequestered calcium ion into cytosol by endoplasmic reticulum	biological process	GO:1903514	10	1	18204	49	RYR3
2.660e-02	-3.63	regulation of mesenchymal stem cell differentiation	biological process	GO:2000739	10	1	18204	49	SOX5
2.660e-02	-3.63	regulation of behavioral fear response	biological process	GO:2000822	10	1	18204	49	APOE
2.660e-02	-3.63	action potential propagation	biological process	GO:0098870	10	1	18204	49	ATP1A2
2.660e-02	-3.63	postsynaptic membrane assembly	biological process	GO:0097104	10	1	18204	49	NRXN1
2.660e-02	-3.63	regulation of CoA-transferase activity	biological process	GO:1905918	10	1	18204	49	APOE
2.660e-02	-3.63	high-density lipoprotein particle assembly	biological process	GO:0034380	10	1	18204	49	APOE
2.660e-02	-3.63	establishment of centrosome localization	biological process	GO:0051660	10	1	18204	49	PARD3B
2.660e-02	-3.63	negative regulation of sterol biosynthetic process	biological process	GO:0106119	10	1	18204	49	APOE
2.660e-02	-3.63	neuronal action potential propagation	biological process	GO:0019227	10	1	18204	49	ATP1A2
2.660e-02	-3.63	learned vocalization behavior or vocal learning	biological process	GO:0098598	10	1	18204	49	NRXN1
2.660e-02	-3.63	negative regulation of cholesterol biosynthetic process	biological process	GO:0045541	10	1	18204	49	APOE
2.660e-02	-3.63	postsynaptic density assembly	biological process	GO:0097107	10	1	18204	49	NRXN1
2.662e-02	-3.63	metal ion transport	biological process	GO:0030001	630	5	18204	49	ATP1A2,SLC4A4,SLC1A3,RYR3,GPM6A
2.666e-02	-3.62	TGFBR1 (transforming growth factor beta receptor 1)	protein interactions	7046	251	3	19454	50	PREX2,BMPR1B,CLU
2.668e-02	-3.62	MIR_motif	interpro domains	IPR016093	10	1	18521	50	RYR3
2.668e-02	-3.62	MIR_dom_sf	interpro domains	IPR036300	10	1	18521	50	RYR3
2.668e-02	-3.62	PAS_fold_3	interpro domains	IPR013655	10	1	18521	50	NPAS3
2.668e-02	-3.62	HCO3_transpt-like_TM_dom	interpro domains	IPR011531	10	1	18521	50	SLC4A4
2.668e-02	-3.62	HCO3_transpt_euk	interpro domains	IPR003020	10	1	18521	50	SLC4A4
2.668e-02	-3.62	PTrfase/Anion_transptr	interpro domains	IPR016152	10	1	18521	50	SLC4A4
2.680e-02	-3.62	TNKS (tankyrase)	protein interactions	8658	99	2	19454	50	TNIK,PCDH9
2.680e-02	-3.62	TPP1 (tripeptidyl peptidase 1)	protein interactions	1200	99	2	19454	50	APOE,PON2
2.680e-02	-3.62	ZFHX3 (zinc finger homeobox 3)	protein interactions	463	99	2	19454	50	SOX5,TRPS1
2.681e-02	-3.62	Terminal pathway of complement	REACTOME pathways	R-HSA-166665	9	1	10285	31	CLU
2.681e-02	-3.62	Synthesis of 5-eicosatetraenoic acids	REACTOME pathways	R-HSA-2142688	9	1	10285	31	PON2
2.693e-02	-3.61	CRX (cone-rod homeobox)	protein interactions	1406	252	3	19454	50	NFIA,TRPS1,SOX5
2.697e-02	-3.61	Transmission across Chemical Synapses	REACTOME pathways	R-HSA-112315	217	3	10285	31	SLC1A3,GLUL,SLC1A2
2.706e-02	-3.61	GS	smart domains	SM00467	7	1	9717	38	BMPR1B
2.725e-02	-3.60	GATA_ZN_FINGER_1	prosite domains	PS00344	8	1	12186	42	TRPS1
2.731e-02	-3.60	ATP4A (ATPase H+/K+ transporting subunit alpha)	protein interactions	495	100	2	19454	50	GPM6A,ATP1A2
2.731e-02	-3.60	EDEM2 (ER degradation enhancing alpha-mannosidase like protein 2)	protein interactions	55741	100	2	19454	50	CLU,HPSE2
2.775e-02	-3.58	MIR	pfam domains	PF02815	10	1	17795	50	RYR3
2.775e-02	-3.58	PAS_3	pfam domains	PF08447	10	1	17795	50	NPAS3
2.775e-02	-3.58	HCO3_cotransp	pfam domains	PF00955	10	1	17795	50	SLC4A4
2.776e-02	-3.58	DYNLL2 (dynein light chain LC8-type 2)	protein interactions	140735	255	3	19454	50	NHSL1,NFIA,TRPS1
2.781e-02	-3.58	CLEC4A (C-type lectin domain family 4 member A)	protein interactions	50856	101	2	19454	50	FGFR3,CTNNA2
2.782e-02	-3.58	amino acid transmembrane transporter activity	molecular function	GO:0015171	100	2	18094	47	SLC1A3,SLC1A2
2.786e-02	-3.58	perisynaptic extracellular matrix	cellular component	GO:0098966	11	1	19108	49	PTPRZ1
2.792e-02	-3.58	AQP5 (aquaporin 5)	protein interactions	362	11	1	19454	50	ATP1A2
2.792e-02	-3.58	SYN3 (synapsin III)	protein interactions	8224	11	1	19454	50	GPM6A
2.792e-02	-3.58	MSRB1 (methionine sulfoxide reductase B1)	protein interactions	51734	11	1	19454	50	CLU
2.792e-02	-3.58	Gtf2e2 (general transcription factor II E, polypeptide 2 (beta subunit))	protein interactions	68153	11	1	19454	50	NHSL1
2.792e-02	-3.58	CCDC17 (coiled-coil domain containing 17)	protein interactions	149483	11	1	19454	50	FGFR3
2.792e-02	-3.58	SYTL1 (synaptotagmin like 1)	protein interactions	84958	11	1	19454	50	NRXN1
2.792e-02	-3.58	NTS (neurotensin)	protein interactions	4922	11	1	19454	50	CPE
2.792e-02	-3.58	IL7 (interleukin 7)	protein interactions	3574	11	1	19454	50	QKI
2.792e-02	-3.58	PTGDR (prostaglandin D2 receptor)	protein interactions	5729	11	1	19454	50	PTGDS
2.792e-02	-3.58	DAZ1 (deleted in azoospermia 1)	protein interactions	1617	11	1	19454	50	QKI
2.810e-02	-3.57	amino acid transmembrane transport	biological process	GO:0003333	97	2	18204	49	SLC1A3,SLC1A2
2.817e-02	-3.57	amide binding	molecular function	GO:0033218	254	3	18094	47	CST3,APOE,CLU
2.821e-02	-3.57	sulfur amino acid transmembrane transporter activity	molecular function	GO:0000099	11	1	18094	47	SLC1A2
2.821e-02	-3.57	acetylcholine receptor binding	molecular function	GO:0033130	11	1	18094	47	NRXN1
2.832e-02	-3.56	human chr8q12.3	chromosome location	human chr8q12.3	15	1	26134	50	NKAIN3
2.832e-02	-3.56	MIR7-1 (microRNA 7-1)	protein interactions	407043	102	2	19454	50	MSI2,QKI
2.849e-02	-3.56	protein binding	molecular function	GO:0005515	13983	42	18094	47	PTPRZ1,DTNA,NPAS3,HPSE2,GLUL,CTNNA2,RYR3,RORA,CDH20,CLU,SPARCL1,NRXN1,NTM,SLC1A2,APOE,TRPS1,MAML2,PITPNC1,PARD3B,CST3,COL5A3,CPE,FBXL7,PTGDS,QKI,GPC5,SOX5,NFIA,HIF3A,GLIS3,ZNRF3,ATP1A2,SLC4A4,PON2,BMPR1B,SLC1A3,FGFR3,LSAMP,TNIK,AHCYL2,MSI2,GPM6A
2.855e-02	-3.56	Heparan sulfate degradation	KEGG pathways	hsa_M00078	9	1	7161	23	HPSE2
2.855e-02	-3.56	Heparan sulfate degradation	KEGG pathways	M00078	9	1	7161	23	HPSE2
2.875e-02	-3.55	renal_cell_carcinoma_unclassified	COSMIC cancer mutations	renal_cell_carcinoma_unclassified	10	1	16828	49	FGFR3
2.875e-02	-3.55	lung-carcinoma-pleomorphic_carcinoma	COSMIC cancer mutations	lung-carcinoma-pleomorphic_carcinoma	10	1	16828	49	FGFR3
2.875e-02	-3.55	skin-back-malignant_melanoma-nodular	COSMIC cancer mutations	skin-back-malignant_melanoma-nodular	10	1	16828	49	PREX2
2.875e-02	-3.55	cervix-in_situ_neoplasm-cervical_intraepithelial_neoplasia_Grade_III	COSMIC cancer mutations	cervix-in_situ_neoplasm-cervical_intraepithelial_neoplasia_Grade_III	10	1	16828	49	FGFR3
2.875e-02	-3.55	kidney-carcinoma-renal_cell_carcinoma_unclassified	COSMIC cancer mutations	kidney-carcinoma-renal_cell_carcinoma_unclassified	10	1	16828	49	FGFR3
2.875e-02	-3.55	cervical_intraepithelial_neoplasia_Grade_III	COSMIC cancer mutations	cervical_intraepithelial_neoplasia_Grade_III	10	1	16828	49	FGFR3
2.875e-02	-3.55	intradermal	COSMIC cancer mutations	intradermal	10	1	16828	49	FGFR3
2.875e-02	-3.55	chiasm	COSMIC cancer mutations	chiasm	10	1	16828	49	QKI
2.884e-02	-3.55	RAB6B (RAB6B, member RAS oncogene family)	protein interactions	51560	103	2	19454	50	BMPR1B,GPM6A
2.894e-02	-3.54	Ig-like_dom	interpro domains	IPR007110	432	4	18521	50	NTM,LSAMP,FGFR3,HEPACAM
2.917e-02	-3.53	bone morphogenesis	biological process	GO:0060349	99	2	18204	49	BMPR1B,FGFR3
2.917e-02	-3.53	phospholipid transport	biological process	GO:0015914	99	2	18204	49	APOE,PITPNC1
2.922e-02	-3.53	L-ascorbic acid metabolic process	biological process	GO:0019852	11	1	18204	49	ATP1A2
2.922e-02	-3.53	antral ovarian follicle growth	biological process	GO:0001547	11	1	18204	49	BMPR1B
2.922e-02	-3.53	establishment or maintenance of transmembrane electrochemical gradient	biological process	GO:0010248	11	1	18204	49	ATP1A2
2.922e-02	-3.53	regulation of fear response	biological process	GO:1903365	11	1	18204	49	APOE
2.922e-02	-3.53	intracellular mRNA localization	biological process	GO:0008298	11	1	18204	49	QKI
2.922e-02	-3.53	regulation of receptor catabolic process	biological process	GO:2000644	11	1	18204	49	APOE
2.922e-02	-3.53	negative regulation of cholesterol metabolic process	biological process	GO:0090206	11	1	18204	49	APOE
2.922e-02	-3.53	lactone metabolic process	biological process	GO:1901334	11	1	18204	49	ATP1A2
2.922e-02	-3.53	cellular response to caffeine	biological process	GO:0071313	11	1	18204	49	RYR3
2.922e-02	-3.53	polyamine transport	biological process	GO:0015846	11	1	18204	49	ATP13A4
2.931e-02	-3.53	Fib_collagen_C	interpro domains	IPR000885	11	1	18521	50	COL5A3
2.932e-02	-3.53	peptide binding	molecular function	GO:0042277	258	3	18094	47	APOE,CLU,CST3
2.936e-02	-3.53	HUNK (hormonally up-regulated Neu-associated kinase)	protein interactions	30811	104	2	19454	50	SPARCL1,CLU
2.975e-02	-3.51	Signaling by FGFR3 fusions in cancer	REACTOME pathways	R-HSA-8853334	10	1	10285	31	FGFR3
2.976e-02	-3.51	Phase I biotransformations, non P450	WikiPathways	WP136	8	1	5310	20	PON2
2.988e-02	-3.51	BEND3 (BEN domain containing 3)	protein interactions	57673	105	2	19454	50	TNIK,TRPS1
2.988e-02	-3.51	ABCA2 (ATP binding cassette subfamily A member 2)	protein interactions	20	105	2	19454	50	PON2,FGFR3
3.000e-02	-3.51	Helical hairpin bin	gene3d domains	1.10.287.570	10	1	14470	44	SLC4A4
3.022e-02	-3.50	GATAZNFINGER	prints domains	PR00619	8	1	5227	20	TRPS1
3.022e-02	-3.50	LIPOCALIN	prints domains	PR00179	8	1	5227	20	PTGDS
3.027e-02	-3.50	cholesterol homeostasis	biological process	GO:0042632	101	2	18204	49	RORA,APOE
3.035e-02	-3.49	banded collagen fibril	cellular component	GO:0098643	12	1	19108	49	COL5A3
3.035e-02	-3.49	fibrillar collagen trimer	cellular component	GO:0005583	12	1	19108	49	COL5A3
3.035e-02	-3.49	sodium:potassium-exchanging ATPase complex	cellular component	GO:0005890	12	1	19108	49	ATP1A2
3.035e-02	-3.49	synapse-associated extracellular matrix	cellular component	GO:0099535	12	1	19108	49	PTPRZ1
3.039e-02	-3.49	skin-hand-carcinoma-squamous_cell_carcinoma	COSMIC cancer mutations	skin-hand-carcinoma-squamous_cell_carcinoma	407	4	16828	49	SLC4A4,FGFR3,COL5A3,HIF3A
3.040e-02	-3.49	USP30 (ubiquitin specific peptidase 30)	protein interactions	84749	106	2	19454	50	QKI,FGFR3
3.042e-02	-3.49	ART4 (ADP-ribosyltransferase 4 (inactive) (Dombrock blood group))	protein interactions	420	12	1	19454	50	GPM6A
3.042e-02	-3.49	UGT1A9 (UDP glucuronosyltransferase family 1 member A9)	protein interactions	54600	12	1	19454	50	PON2
3.042e-02	-3.49	MMP25 (matrix metallopeptidase 25)	protein interactions	64386	12	1	19454	50	CLU
3.042e-02	-3.49	PROK2 (prokineticin 2)	protein interactions	60675	12	1	19454	50	CPE
3.042e-02	-3.49	LGR5 (leucine rich repeat containing G protein-coupled receptor 5)	protein interactions	8549	12	1	19454	50	ZNRF3
3.042e-02	-3.49	LMP-1 (latent membrane protein LMP-1)	protein interactions	3783750	12	1	19454	50	TNIK
3.042e-02	-3.49	BAMBI (BMP and activin membrane bound inhibitor)	protein interactions	25805	12	1	19454	50	BMPR1B
3.042e-02	-3.49	CA4 (carbonic anhydrase 4)	protein interactions	762	12	1	19454	50	SLC4A4
3.049e-02	-3.49	COLFI	pfam domains	PF01410	11	1	17795	50	COL5A3
3.049e-02	-3.49	PAS_11	pfam domains	PF14598	11	1	17795	50	HIF3A
3.058e-02	-3.49	CTNNB1 (catenin beta 1)	protein interactions	1499	926	6	19454	50	NHSL1,DTNA,PTPRZ1,PARD3B,CTNNA2,APOE
3.060e-02	-3.49	CYSTATIN	prosite domains	PS00287	9	1	12186	42	CST3
3.063e-02	-3.49	spleen	COSMIC cancer mutations	spleen	408	4	16828	49	NTM,PTPRZ1,PARD3B,TNIK
3.073e-02	-3.48	DNA-binding transcription factor activity	molecular function	GO:0003700	1441	8	18094	47	NPAS3,SOX5,TRPS1,HIF3A,GLIS3,NFIA,RORA,ZBTB20
3.079e-02	-3.48	DNA-binding transcription repressor activity, RNA polymerase II-specific	molecular function	GO:0001227	263	3	18094	47	GLIS3,ZBTB20,TRPS1
3.082e-02	-3.48	sterol homeostasis	biological process	GO:0055092	102	2	18204	49	RORA,APOE
3.092e-02	-3.48	POMK (protein O-mannose kinase)	protein interactions	84197	266	3	19454	50	BMPR1B,CLU,PON2
3.111e-02	-3.47	Post-translational modification: synthesis of GPI-anchored proteins	REACTOME pathways	R-HSA-163125	92	2	10285	31	LSAMP,NTM
3.139e-02	-3.46	calcium ion binding	molecular function	GO:0005509	683	5	18094	47	SPARCL1,NRXN1,PAMR1,RYR3,PCDH9
3.147e-02	-3.46	FKBP1A (FKBP prolyl isomerase 1A)	protein interactions	2280	108	2	19454	50	RYR3,MSI2
3.147e-02	-3.46	PAX8 (paired box 8)	protein interactions	7849	108	2	19454	50	TRPS1,NFIA
3.147e-02	-3.46	CAMKV (CaM kinase like vesicle associated)	protein interactions	79012	108	2	19454	50	GPM6A,AHCYL2
3.147e-02	-3.46	BIN1 (bridging integrator 1)	protein interactions	274	108	2	19454	50	CLU,GPM6A
3.151e-02	-3.46	steroid binding	molecular function	GO:0005496	107	2	18094	47	ATP1A2,RORA
3.155e-02	-3.46	regulation of multicellular organismal process	biological process	GO:0051239	3113	14	18204	49	SOX5,PTGDS,NRXN1,CST3,APOE,ATP1A2,TRPS1,PTPRZ1,QKI,RORA,BMPR1B,ZBTB20,GLUL,CLU
3.158e-02	-3.46	prostate-hyperplasia	COSMIC cancer mutations	prostate-hyperplasia	11	1	16828	49	FGFR3
3.158e-02	-3.46	skin-neck-carcinoma-basal_cell_carcinoma	COSMIC cancer mutations	skin-neck-carcinoma-basal_cell_carcinoma	11	1	16828	49	FGFR3
3.158e-02	-3.46	kidney-other-oncocytoma	COSMIC cancer mutations	kidney-other-oncocytoma	11	1	16828	49	FGFR3
3.158e-02	-3.46	skin-back-malignant_melanoma-superficial_spreading	COSMIC cancer mutations	skin-back-malignant_melanoma-superficial_spreading	11	1	16828	49	PREX2
3.158e-02	-3.46	pleomorphic_carcinoma	COSMIC cancer mutations	pleomorphic_carcinoma	11	1	16828	49	FGFR3
3.158e-02	-3.46	seborrhoeic_keratosis	COSMIC cancer mutations	seborrhoeic_keratosis	11	1	16828	49	FGFR3
3.158e-02	-3.46	oncocytoma	COSMIC cancer mutations	oncocytoma	11	1	16828	49	FGFR3
3.158e-02	-3.46	skin-scalp-carcinoma-basal_cell_carcinoma	COSMIC cancer mutations	skin-scalp-carcinoma-basal_cell_carcinoma	11	1	16828	49	FGFR3
3.158e-02	-3.46	congenital	COSMIC cancer mutations	congenital	11	1	16828	49	FGFR3
3.158e-02	-3.46	skin-hand-malignant_melanoma-acral_lentiginous	COSMIC cancer mutations	skin-hand-malignant_melanoma-acral_lentiginous	11	1	16828	49	PREX2
3.168e-02	-3.45	Methionine degradation	KEGG pathways	hsa_M00035	10	1	7161	23	AHCYL2
3.168e-02	-3.45	Methionine degradation	KEGG pathways	M00035	10	1	7161	23	AHCYL2
3.179e-02	-3.45	NAD+ Signalling and Aging	SMPDB pathways	SMP0084271	11	1	1369	4	RORA
3.184e-02	-3.45	negative regulation of collagen metabolic process	biological process	GO:0010713	12	1	18204	49	CST3
3.184e-02	-3.45	regulation of blood vessel remodeling	biological process	GO:0060312	12	1	18204	49	CST3
3.184e-02	-3.45	positive regulation of extrinsic apoptotic signaling pathway via death domain receptors	biological process	GO:1902043	12	1	18204	49	BMPR1B
3.184e-02	-3.45	microglia differentiation	biological process	GO:0014004	12	1	18204	49	QKI
3.184e-02	-3.45	mammalian oogenesis stage	biological process	GO:0022605	12	1	18204	49	BMPR1B
3.184e-02	-3.45	neurotransmitter-gated ion channel clustering	biological process	GO:0072578	12	1	18204	49	APOE
3.184e-02	-3.45	sulfur amino acid transport	biological process	GO:0000101	12	1	18204	49	SLC1A2
3.193e-02	-3.44	MAD_homology1_Dwarfin-type	interpro domains	IPR003619	12	1	18521	50	NFIA
3.193e-02	-3.44	Lipocalin_CS	interpro domains	IPR022272	12	1	18521	50	PTGDS
3.193e-02	-3.44	Lipocalin	interpro domains	IPR002345	12	1	18521	50	PTGDS
3.193e-02	-3.44	TGFB_receptor	interpro domains	IPR000333	12	1	18521	50	BMPR1B
3.194e-02	-3.44	regulation of steroid metabolic process	biological process	GO:0019218	104	2	18204	49	APOE,RORA
3.200e-02	-3.44	MIR34B (microRNA 34b)	protein interactions	407041	109	2	19454	50	QKI,MSI2
3.207e-02	-3.44	biliary_tract-bile_duct-carcinoma-adenocarcinoma	COSMIC cancer mutations	biliary_tract-bile_duct-carcinoma-adenocarcinoma	15095	48	16828	49	CST3,DTNA,MSI2,FBXL7,SOX5,SPARCL1,PON2,COL5A3,TRPS1,HEPACAM,HIF3A,ATP13A4,FGFR3,NTM,NHSL1,CDH20,PITPNC1,AHCYL2,SLC4A4,CLU,ATP1A2,PAMR1,LSAMP,GPM6A,ZBTB20,GPC5,NFIA,RORA,TNIK,HPSE2,RYR3,QKI,NPAS3,SLC1A2,PTPRZ1,GLUL,BMPR1B,GLIS3,NRXN1,PTGDS,ZNRF3,PCDH9,MAML2,PREX2,SLC1A3,PARD3B,CPE,APOE
3.207e-02	-3.44	bile_duct	COSMIC cancer mutations	bile_duct	15095	48	16828	49	SLC1A3,PREX2,PARD3B,CPE,APOE,NRXN1,GLIS3,MAML2,PTGDS,ZNRF3,PCDH9,PTPRZ1,NPAS3,SLC1A2,GLUL,BMPR1B,ZBTB20,GPC5,GPM6A,NFIA,HPSE2,TNIK,RYR3,RORA,QKI,NHSL1,CDH20,PITPNC1,ATP1A2,CLU,SLC4A4,AHCYL2,LSAMP,PAMR1,HIF3A,HEPACAM,TRPS1,NTM,ATP13A4,FGFR3,PON2,COL5A3,MSI2,DTNA,CST3,FBXL7,SOX5,SPARCL1
3.213e-02	-3.44	ATXN1 (ataxin 1)	protein interactions	6310	469	4	19454	50	NFIA,PTGDS,CST3,QKI
3.229e-02	-3.43	organic anion transmembrane transporter activity	molecular function	GO:0008514	268	3	18094	47	SLC4A4,SLC1A2,SLC1A3
3.240e-02	-3.43	EF-hand-dom_pair	interpro domains	IPR011992	258	3	18521	50	RYR3,DTNA,SPARCL1
3.254e-02	-3.43	LZTR1 (leucine zipper like post translational regulator 1)	protein interactions	8216	110	2	19454	50	BMPR1B,PARD3B
3.254e-02	-3.43	SCARB1 (scavenger receptor class B member 1)	protein interactions	949	110	2	19454	50	APOE,PON2
3.263e-02	-3.42	Protein digestion and absorption	KEGG pathways	hsa04974	89	2	7161	23	ATP1A2,COL5A3
3.263e-02	-3.42	Protein digestion and absorption	KEGG pathways	ko04974	89	2	7161	23	COL5A3,ATP1A2
3.284e-02	-3.42	chylomicron	cellular component	GO:0042627	13	1	19108	49	APOE
3.291e-02	-3.41	PCDHA2 (protocadherin alpha 2)	protein interactions	56146	13	1	19454	50	NFIA
3.291e-02	-3.41	ST3GAL5 (ST3 beta-galactoside alpha-2,3-sialyltransferase 5)	protein interactions	8869	13	1	19454	50	PON2
3.291e-02	-3.41	RAB3C (RAB3C, member RAS oncogene family)	protein interactions	115827	13	1	19454	50	GPM6A
3.291e-02	-3.41	MYO16 (myosin XVI)	protein interactions	23026	13	1	19454	50	NRXN1
3.291e-02	-3.41	Rbm47 (RNA binding motif protein 47)	protein interactions	245945	13	1	19454	50	QKI
3.291e-02	-3.41	TBCC (tubulin folding cofactor C)	protein interactions	6903	13	1	19454	50	NTM
3.291e-02	-3.41	ANKH (ANKH inorganic pyrophosphate transport regulator)	protein interactions	56172	13	1	19454	50	APOE
3.291e-02	-3.41	PLPPR4 (phospholipid phosphatase related 4)	protein interactions	9890	13	1	19454	50	ZNRF3
3.296e-02	-3.41	Carboxypeptidase-like, regulatory domain	gene3d domains	2.60.40.1120	11	1	14470	44	CPE
3.309e-02	-3.41	cell-cell adhesion via plasma-membrane adhesion molecules	biological process	GO:0098742	261	3	18204	49	PCDH9,CDH20,SPARCL1
3.321e-02	-3.40	CarboxypepD_reg	pfam domains	PF13620	12	1	17795	50	CPE
3.321e-02	-3.40	MH1	pfam domains	PF03165	12	1	17795	50	NFIA
3.322e-02	-3.40	sulfur compound binding	molecular function	GO:1901681	271	3	18094	47	APOE,HPSE2,COL5A3
3.326e-02	-3.40	monoatomic cation:bicarbonate symporter activity	molecular function	GO:0140410	13	1	18094	47	SLC4A4
3.326e-02	-3.40	potassium ion binding	molecular function	GO:0030955	13	1	18094	47	ATP1A2
3.326e-02	-3.40	transforming growth factor beta receptor activity	molecular function	GO:0005024	13	1	18094	47	BMPR1B
3.332e-02	-3.40	tube development	biological process	GO:0035295	903	6	18204	49	HIF3A,APOE,RORA,QKI,NFIA,GLUL
3.353e-02	-3.40	DNA-binding transcription repressor activity	molecular function	GO:0001217	272	3	18094	47	GLIS3,ZBTB20,TRPS1
3.387e-02	-3.39	skin-arm-malignant_melanoma	COSMIC cancer mutations	skin-arm-malignant_melanoma	1308	8	16828	49	TRPS1,ZBTB20,NPAS3,COL5A3,ATP1A2,PARD3B,NTM,SLC4A4
3.388e-02	-3.38	regulation of developmental process	biological process	GO:0050793	2540	12	18204	49	SOX5,APOE,FGFR3,NRXN1,CST3,PTPRZ1,QKI,RORA,BMPR1B,TRPS1,TNIK,GLUL
3.389e-02	-3.38	human chr7q31.32	chromosome location	human chr7q31.32	18	1	26134	50	PTPRZ1
3.389e-02	-3.38	human chr18q21.33	chromosome location	human chr18q21.33	18	1	26134	50	CDH20
3.395e-02	-3.38	MIR	prosite domains	PS50919	10	1	12186	42	RYR3
3.405e-02	-3.38	NR3C1 (nuclear receptor subfamily 3 group C member 1)	protein interactions	2908	950	6	19454	50	NFIA,SLC1A3,ZBTB20,PON2,TRPS1,ATP13A4
3.418e-02	-3.38	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-acute_lymphoblastic_leukaemia	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-acute_lymphoblastic_leukaemia	2081	11	16828	49	NFIA,TRPS1,DTNA,SOX5,TNIK,FGFR3,PTPRZ1,PREX2,BMPR1B,ATP1A2,SLC4A4
3.418e-02	-3.38	GFI1B (growth factor independent 1B transcriptional repressor)	protein interactions	8328	113	2	19454	50	ZNRF3,DTNA
3.438e-02	-3.37	stomach-carcinoma-diffuse_adenocarcinoma	COSMIC cancer mutations	stomach-carcinoma-diffuse_adenocarcinoma	4383	19	16828	49	ZNRF3,PCDH9,FGFR3,SOX5,RYR3,QKI,GLIS3,GPM6A,DTNA,TRPS1,HIF3A,GLUL,CLU,ATP1A2,NHSL1,PON2,PREX2,PTPRZ1,SLC1A3
3.438e-02	-3.37	diffuse_adenocarcinoma	COSMIC cancer mutations	diffuse_adenocarcinoma	4383	19	16828	49	TRPS1,HIF3A,DTNA,GLIS3,GPM6A,QKI,FGFR3,PCDH9,ZNRF3,RYR3,SOX5,PON2,NHSL1,SLC1A3,PREX2,PTPRZ1,GLUL,ATP1A2,CLU
3.439e-02	-3.37	regulation of canonical Wnt signaling pathway	biological process	GO:0060828	265	3	18204	49	GPC5,ZNRF3,APOE
3.440e-02	-3.37	cervix-carcinoma-mixed_adenosquamous_carcinoma	COSMIC cancer mutations	cervix-carcinoma-mixed_adenosquamous_carcinoma	12	1	16828	49	FGFR3
3.440e-02	-3.37	central_nervous_system-fourth_ventricle-glioma-astrocytoma_Grade_I	COSMIC cancer mutations	central_nervous_system-fourth_ventricle-glioma-astrocytoma_Grade_I	12	1	16828	49	QKI
3.440e-02	-3.37	skin-benign_melanocytic_nevus	COSMIC cancer mutations	skin-benign_melanocytic_nevus	12	1	16828	49	FGFR3
3.440e-02	-3.37	skin-abdomen-malignant_melanoma-nodular	COSMIC cancer mutations	skin-abdomen-malignant_melanoma-nodular	12	1	16828	49	PREX2
3.440e-02	-3.37	skin-face-carcinoma-basal_cell_carcinoma	COSMIC cancer mutations	skin-face-carcinoma-basal_cell_carcinoma	12	1	16828	49	FGFR3
3.444e-02	-3.37	phospholipid efflux	biological process	GO:0033700	13	1	18204	49	APOE
3.444e-02	-3.37	glial cell fate commitment	biological process	GO:0021781	13	1	18204	49	NFIA
3.444e-02	-3.37	regulation of dendritic spine maintenance	biological process	GO:1902950	13	1	18204	49	APOE
3.444e-02	-3.37	postsynaptic specialization assembly	biological process	GO:0098698	13	1	18204	49	NRXN1
3.444e-02	-3.37	T-helper 17 cell differentiation	biological process	GO:0072539	13	1	18204	49	RORA
3.444e-02	-3.37	negative regulation of cytosolic calcium ion concentration	biological process	GO:0051481	13	1	18204	49	ATP1A2
3.444e-02	-3.37	regulation of respiratory gaseous exchange by nervous system process	biological process	GO:0002087	13	1	18204	49	ATP1A2
3.444e-02	-3.37	prepulse inhibition	biological process	GO:0060134	13	1	18204	49	CTNNA2
3.444e-02	-3.37	cerebellar Purkinje cell differentiation	biological process	GO:0021702	13	1	18204	49	RORA
3.464e-02	-3.36	Lactose Degradation	SMPDB pathways	SMP0000457	12	1	1369	4	ATP1A2
3.464e-02	-3.36	Lactose Intolerance	SMPDB pathways	SMP0000458	12	1	1369	4	ATP1A2
3.466e-02	-3.36	small molecule biosynthetic process	biological process	GO:0044283	459	4	18204	49	PTGDS,SLC1A3,GLUL,QKI
3.466e-02	-3.36	FOLN	smart domains	SM00274	9	1	9717	38	SPARCL1
3.474e-02	-3.36	ORF3b (ORF3b protein)	protein interactions	1489670	114	2	19454	50	ZBTB20,PCDH9
3.481e-02	-3.36	long-chain fatty acid metabolic process	biological process	GO:0001676	109	2	18204	49	QKI,PTGDS
3.481e-02	-3.36	postsynapse organization	biological process	GO:0099173	109	2	18204	49	APOE,NRXN1
3.481e-02	-3.36	positive regulation of tumor necrosis factor production	biological process	GO:0032760	109	2	18204	49	ZBTB20,CLU
3.500e-02	-3.35	Cadherin_CS	interpro domains	IPR020894	109	2	18521	50	PCDH9,CDH20
3.530e-02	-3.34	SMAD7 (SMAD family member 7)	protein interactions	4092	115	2	19454	50	BMPR1B,SOX5
3.530e-02	-3.34	TBXT (T-box transcription factor T)	protein interactions	6862	115	2	19454	50	TRPS1,NFIA
3.532e-02	-3.34	chromaffin granule	cellular component	GO:0042583	14	1	19108	49	CLU
3.537e-02	-3.34	protein localization to membrane	biological process	GO:0072657	462	4	18204	49	CPE,NRXN1,TNIK,APOE
3.540e-02	-3.34	VSX2 (visual system homeobox 2)	protein interactions	338917	14	1	19454	50	AHCYL2
3.540e-02	-3.34	Nedd4 (neural precursor cell expressed, developmentally down-regulated 4)	protein interactions	17999	14	1	19454	50	GLIS3
3.540e-02	-3.34	IFNA8 (interferon alpha 8)	protein interactions	3445	14	1	19454	50	APOE
3.540e-02	-3.34	Stag2 (STAG2 cohesin complex component)	protein interactions	20843	14	1	19454	50	CLU
3.540e-02	-3.34	SYT5 (synaptotagmin 5)	protein interactions	6861	14	1	19454	50	NRXN1
3.540e-02	-3.34	SLC1A2 (solute carrier family 1 member 2)	protein interactions	6506	14	1	19454	50	SLC1A2
3.540e-02	-3.34	DACT2 (dishevelled binding antagonist of beta catenin 2)	protein interactions	168002	14	1	19454	50	ZBTB20
3.540e-02	-3.34	CTSO (cathepsin O)	protein interactions	1519	14	1	19454	50	CST3
3.540e-02	-3.34	RHEBL1 (RHEB like 1)	protein interactions	121268	14	1	19454	50	BMPR1B
3.540e-02	-3.34	RSPO1 (R-spondin 1)	protein interactions	284654	14	1	19454	50	ZNRF3
3.540e-02	-3.34	MB (myoglobin)	protein interactions	4151	14	1	19454	50	MAML2
3.540e-02	-3.34	FGF7 (fibroblast growth factor 7)	protein interactions	2252	14	1	19454	50	FGFR3
3.540e-02	-3.34	Aifm1 (apoptosis-inducing factor, mitochondrion-associated 1)	protein interactions	26926	14	1	19454	50	CLU
3.559e-02	-3.34	Regulation of gene expression by Hypoxia-inducible Factor	REACTOME pathways	R-HSA-1234158	12	1	10285	31	HIF3A
3.559e-02	-3.34	Defective EXT2 causes exostoses 2	REACTOME pathways	R-HSA-3656237	12	1	10285	31	GPC5
3.559e-02	-3.34	FGFR3 mutant receptor activation	REACTOME pathways	R-HSA-2033514	12	1	10285	31	FGFR3
3.559e-02	-3.34	Defective EXT1 causes exostoses 1, TRPS2 and CHDS	REACTOME pathways	R-HSA-3656253	12	1	10285	31	GPC5
3.559e-02	-3.34	Signaling by activated point mutants of FGFR3	REACTOME pathways	R-HSA-1839130	12	1	10285	31	FGFR3
3.570e-02	-3.33	blood microparticle	cellular component	GO:0072562	116	2	19108	49	CLU,APOE
3.574e-02	-3.33	human chr11q25	chromosome location	human chr11q25	19	1	26134	50	NTM
3.574e-02	-3.33	human chr6q24.1	chromosome location	human chr6q24.1	19	1	26134	50	NHSL1
3.581e-02	-3.33	central_nervous_system-brain-glioma-oligodendroglioma_Grade_III	COSMIC cancer mutations	central_nervous_system-brain-glioma-oligodendroglioma_Grade_III	249	3	16828	49	PTPRZ1,FGFR3,GLIS3
3.586e-02	-3.33	SKIL (SKI like proto-oncogene)	protein interactions	6498	116	2	19454	50	GLUL,SPARCL1
3.586e-02	-3.33	RBBP8 (RB binding protein 8, endonuclease)	protein interactions	5932	116	2	19454	50	CTNNA2,CLU
3.588e-02	-3.33	transcription cis-regulatory region binding	molecular function	GO:0000976	1485	8	18094	47	TRPS1,SOX5,NPAS3,NFIA,HIF3A,GLIS3,RORA,ZBTB20
3.590e-02	-3.33	Alpha-catenin/vinculin-like	gene3d domains	1.20.120.230	12	1	14470	44	CTNNA2
3.593e-02	-3.33	skin-upper_leg-malignant_melanoma	COSMIC cancer mutations	skin-upper_leg-malignant_melanoma	850	6	16828	49	PREX2,PCDH9,GLIS3,HIF3A,NFIA,PAMR1
3.613e-02	-3.32	transcription regulatory region nucleic acid binding	molecular function	GO:0001067	1487	8	18094	47	ZBTB20,RORA,HIF3A,GLIS3,NFIA,NPAS3,TRPS1,SOX5
3.617e-02	-3.32	small_intestine	COSMIC cancer mutations	small_intestine	250	3	16828	49	TNIK,ZNRF3,FGFR3
3.631e-02	-3.32	tube morphogenesis	biological process	GO:0035239	685	5	18204	49	QKI,RORA,APOE,HIF3A,GLUL
3.642e-02	-3.31	SYT6 (synaptotagmin 6)	protein interactions	148281	117	2	19454	50	NRXN1,AHCYL2
3.642e-02	-3.31	ELK3 (ETS transcription factor ELK3)	protein interactions	2004	117	2	19454	50	NFIA,TRPS1
3.647e-02	-3.31	HYOU1 (hypoxia up-regulated 1)	protein interactions	10525	284	3	19454	50	CLU,CPE,FGFR3
3.657e-02	-3.31	regulation of gliogenesis	biological process	GO:0014013	112	2	18204	49	PTPRZ1,QKI
3.678e-02	-3.30	Pancreatic secretion	KEGG pathways	hsa04972	95	2	7161	23	ATP1A2,SLC4A4
3.678e-02	-3.30	Pancreatic secretion	KEGG pathways	ko04972	95	2	7161	23	SLC4A4,ATP1A2
3.678e-02	-3.30	HLH_DNA-bd_sf	interpro domains	IPR036638	112	2	18521	50	HIF3A,NPAS3
3.678e-02	-3.30	bHLH_dom	interpro domains	IPR011598	112	2	18521	50	HIF3A,NPAS3
3.680e-02	-3.30	P4HA1 (prolyl 4-hydroxylase subunit alpha 1)	protein interactions	5033	285	3	19454	50	APOE,DTNA,PON2
3.691e-02	-3.30	Visual phototransduction	REACTOME pathways	R-HSA-2187338	101	2	10285	31	APOE,GPC5
3.699e-02	-3.30	PLCD3 (phospholipase C delta 3)	protein interactions	113026	118	2	19454	50	TNIK,AHCYL2
3.704e-02	-3.30	relaxation of cardiac muscle	biological process	GO:0055119	14	1	18204	49	ATP1A2
3.704e-02	-3.30	negative regulation of long-term synaptic potentiation	biological process	GO:1900272	14	1	18204	49	APOE
3.704e-02	-3.30	positive regulation of phospholipid transport	biological process	GO:2001140	14	1	18204	49	APOE
3.704e-02	-3.30	glutathione biosynthetic process	biological process	GO:0006750	14	1	18204	49	SLC1A2
3.704e-02	-3.30	negative regulation of sodium ion transmembrane transporter activity	biological process	GO:2000650	14	1	18204	49	ATP1A2
3.704e-02	-3.30	cellular response to purine-containing compound	biological process	GO:0071415	14	1	18204	49	RYR3
3.706e-02	-3.30	Composition of Lipid Particles	WikiPathways	WP3601	10	1	5310	20	APOE
3.710e-02	-3.29	calcium channel activity	molecular function	GO:0005262	117	2	18094	47	RYR3,GPM6A
3.715e-02	-3.29	Neurexin-like	interpro domains	IPR003585	14	1	18521	50	NRXN1
3.717e-02	-3.29	dendrite development	biological process	GO:0016358	113	2	18204	49	CTNNA2,PREX2
3.717e-02	-3.29	positive regulation of tumor necrosis factor superfamily cytokine production	biological process	GO:1903557	113	2	18204	49	CLU,ZBTB20
3.721e-02	-3.29	cervix-carcinoma-adenocarcinoma	COSMIC cancer mutations	cervix-carcinoma-adenocarcinoma	13	1	16828	49	FGFR3
3.721e-02	-3.29	Brenner_tumour	COSMIC cancer mutations	Brenner_tumour	13	1	16828	49	FGFR3
3.721e-02	-3.29	skin-shoulder-malignant_melanoma-nodular	COSMIC cancer mutations	skin-shoulder-malignant_melanoma-nodular	13	1	16828	49	PREX2
3.721e-02	-3.29	skin-scalp-malignant_melanoma-nodular	COSMIC cancer mutations	skin-scalp-malignant_melanoma-nodular	13	1	16828	49	PREX2
3.721e-02	-3.29	skin-back-carcinoma-basal_cell_carcinoma	COSMIC cancer mutations	skin-back-carcinoma-basal_cell_carcinoma	13	1	16828	49	FGFR3
3.721e-02	-3.29	endometrium-ovary-endometriosis	COSMIC cancer mutations	endometrium-ovary-endometriosis	13	1	16828	49	FGFR3
3.721e-02	-3.29	central_nervous_system-hypothalamus-glioma-astrocytoma_Grade_I	COSMIC cancer mutations	central_nervous_system-hypothalamus-glioma-astrocytoma_Grade_I	13	1	16828	49	QKI
3.728e-02	-3.29	LIPOCALIN	prosite domains	PS00213	11	1	12186	42	PTGDS
3.728e-02	-3.29	NC1_FIB	prosite domains	PS51461	11	1	12186	42	COL5A3
3.728e-02	-3.29	GATA_ZN_FINGER_2	prosite domains	PS50114	11	1	12186	42	TRPS1
3.749e-02	-3.28	Trehalose Degradation	SMPDB pathways	SMP0000467	13	1	1369	4	ATP1A2
3.750e-02	-3.28	central_nervous_system-cerebellum-glioma-astrocytoma_Grade_I	COSMIC cancer mutations	central_nervous_system-cerebellum-glioma-astrocytoma_Grade_I	105	2	16828	49	QKI,GPC5
3.759e-02	-3.28	human chr8p21.1	chromosome location	human chr8p21.1	20	1	26134	50	CLU
3.764e-02	-3.28	HCO3TRNSPORT	prints domains	PR01231	10	1	5227	20	SLC4A4
3.777e-02	-3.28	regulation of circadian rhythm	biological process	GO:0042752	114	2	18204	49	PTGDS,RORA
3.779e-02	-3.28	NEDD4 (NEDD4 E3 ubiquitin protein ligase)	protein interactions	4734	494	4	19454	50	TNIK,FGFR3,GLIS3,MAML2
3.780e-02	-3.28	low-density lipoprotein particle	cellular component	GO:0034362	15	1	19108	49	APOE
3.780e-02	-3.28	axolemma	cellular component	GO:0030673	15	1	19108	49	SLC1A2
3.788e-02	-3.27	FGF9 (fibroblast growth factor 9)	protein interactions	2254	15	1	19454	50	FGFR3
3.788e-02	-3.27	TIAM2 (TIAM Rac1 associated GEF 2)	protein interactions	26230	15	1	19454	50	TNIK
3.788e-02	-3.27	IGSF1 (immunoglobulin superfamily member 1)	protein interactions	3547	15	1	19454	50	BMPR1B
3.798e-02	-3.27	Cadherin-like_dom	interpro domains	IPR002126	114	2	18521	50	PCDH9,CDH20
3.814e-02	-3.27	HOXB9 (homeobox B9)	protein interactions	3219	120	2	19454	50	NFIA,AHCYL2
3.819e-02	-3.27	circulatory system development	biological process	GO:0072359	933	6	18204	49	CPE,GLUL,QKI,APOE,RORA,HIF3A
3.828e-02	-3.26	neurexin family protein binding	molecular function	GO:0042043	15	1	18094	47	CPE
3.828e-02	-3.26	phosphatidylglycerol binding	molecular function	GO:1901611	15	1	18094	47	PITPNC1
3.837e-02	-3.26	fatty acid biosynthetic process	biological process	GO:0006633	115	2	18204	49	PTGDS,QKI
3.844e-02	-3.26	MIR	smart domains	SM00472	10	1	9717	38	RYR3
3.850e-02	-3.26	NOTCH2 intracellular domain regulates transcription	REACTOME pathways	R-HSA-2197563	13	1	10285	31	MAML2
3.850e-02	-3.26	Notch-HLH transcription pathway	REACTOME pathways	R-HSA-350054	13	1	10285	31	MAML2
3.850e-02	-3.26	FGFR3c ligand binding and activation	REACTOME pathways	R-HSA-190372	13	1	10285	31	FGFR3
3.850e-02	-3.26	FGFR3 ligand binding and activation	REACTOME pathways	R-HSA-190239	13	1	10285	31	FGFR3
3.850e-02	-3.26	Phospholipase C-mediated cascade; FGFR3	REACTOME pathways	R-HSA-5654227	13	1	10285	31	FGFR3
3.864e-02	-3.25	GATA	pfam domains	PF00320	14	1	17795	50	TRPS1
3.872e-02	-3.25	MED15 (mediator complex subunit 15)	protein interactions	51586	121	2	19454	50	NFIA,QKI
3.881e-02	-3.25	bone-humerus-Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour	COSMIC cancer mutations	bone-humerus-Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour	107	2	16828	49	PARD3B,HIF3A
3.904e-02	-3.24	secondary active transmembrane transporter activity	molecular function	GO:0015291	289	3	18094	47	SLC1A2,SLC4A4,SLC1A3
3.914e-02	-3.24	skin-leg-malignant_melanoma-nodular	COSMIC cancer mutations	skin-leg-malignant_melanoma-nodular	258	3	16828	49	PTPRZ1,SLC4A4,ATP13A4
3.919e-02	-3.24	homeostatic process	biological process	GO:0042592	1456	8	18204	49	ZBTB20,ATP13A4,RYR3,APOE,ATP1A2,SLC4A4,SLC1A3,RORA
3.920e-02	-3.24	Cadherin-like_sf	interpro domains	IPR015919	116	2	18521	50	PCDH9,CDH20
3.930e-02	-3.24	BRK1 (BRICK1 subunit of SCAR/WAVE actin nucleating complex)	protein interactions	55845	122	2	19454	50	NHSL1,DTNA
3.930e-02	-3.24	MED31 (mediator complex subunit 31)	protein interactions	51003	122	2	19454	50	CPE,QKI
3.943e-02	-3.23	human chr13q31.3	chromosome location	human chr13q31.3	21	1	26134	50	GPC5
3.943e-02	-3.23	human chr4q32.3	chromosome location	human chr4q32.3	21	1	26134	50	CPE
3.947e-02	-3.23	testis-germ_cell_tumour-seminoma	COSMIC cancer mutations	testis-germ_cell_tumour-seminoma	648	5	16828	49	TRPS1,BMPR1B,FGFR3,TNIK,PREX2
3.954e-02	-3.23	Cadherin	pfam domains	PF00028	112	2	17795	50	CDH20,PCDH9
3.964e-02	-3.23	system process	biological process	GO:0003008	2015	10	18204	49	CTNNA2,ATP1A2,SLC4A4,APOE,RYR3,NRXN1,PTPRZ1,SLC1A2,DTNA,SLC1A3
3.964e-02	-3.23	regulation of phospholipid transport	biological process	GO:2001138	15	1	18204	49	APOE
3.964e-02	-3.23	neuroblast division	biological process	GO:0055057	15	1	18204	49	SOX5
3.964e-02	-3.23	exit from mitosis	biological process	GO:0010458	15	1	18204	49	NFIA
3.964e-02	-3.23	lipoprotein catabolic process	biological process	GO:0042159	15	1	18204	49	APOE
3.964e-02	-3.23	negative regulation of sodium ion transmembrane transport	biological process	GO:1902306	15	1	18204	49	ATP1A2
3.964e-02	-3.23	response to caffeine	biological process	GO:0031000	15	1	18204	49	RYR3
3.964e-02	-3.23	positive regulation of cholesterol metabolic process	biological process	GO:0090205	15	1	18204	49	APOE
3.964e-02	-3.23	intracellular potassium ion homeostasis	biological process	GO:0030007	15	1	18204	49	ATP1A2
3.964e-02	-3.23	cerebellar Purkinje cell layer formation	biological process	GO:0021694	15	1	18204	49	RORA
3.964e-02	-3.23	sarcoplasmic reticulum calcium ion transport	biological process	GO:0070296	15	1	18204	49	RYR3
3.964e-02	-3.23	regulation of circadian sleep/wake cycle, sleep	biological process	GO:0045187	15	1	18204	49	PTGDS
3.964e-02	-3.23	chondrocyte proliferation	biological process	GO:0035988	15	1	18204	49	FGFR3
3.964e-02	-3.23	protein homotrimerization	biological process	GO:0070207	15	1	18204	49	SLC1A2
3.964e-02	-3.23	synapse maturation	biological process	GO:0060074	15	1	18204	49	NFIA
3.975e-02	-3.23	CNH_dom	interpro domains	IPR001180	15	1	18521	50	TNIK
3.975e-02	-3.23	Znf_GATA	interpro domains	IPR000679	15	1	18521	50	TRPS1
3.975e-02	-3.23	ATPase_P-typ_cation-transptr_C	interpro domains	IPR006068	15	1	18521	50	ATP1A2
3.977e-02	-3.22	KCNE3 (potassium voltage-gated channel subfamily E regulatory subunit 3)	protein interactions	10008	294	3	19454	50	ZNRF3,TNIK,PCDH9
3.988e-02	-3.22	PAX7 (paired box 7)	protein interactions	5081	123	2	19454	50	TRPS1,NFIA
4.002e-02	-3.22	urinary_tract-renal_pelvis-carcinoma-transitional_cell_carcinoma	COSMIC cancer mutations	urinary_tract-renal_pelvis-carcinoma-transitional_cell_carcinoma	14	1	16828	49	FGFR3
4.002e-02	-3.22	in_situ_neoplasm	COSMIC cancer mutations	in_situ_neoplasm	14	1	16828	49	FGFR3
4.002e-02	-3.22	small_round_cell_tumour	COSMIC cancer mutations	small_round_cell_tumour	14	1	16828	49	FGFR3
4.002e-02	-3.22	soft_tissue-small_round_cell_tumour	COSMIC cancer mutations	soft_tissue-small_round_cell_tumour	14	1	16828	49	FGFR3
4.002e-02	-3.22	endometriosis	COSMIC cancer mutations	endometriosis	14	1	16828	49	FGFR3
4.020e-02	-3.21	synapse assembly	biological process	GO:0007416	118	2	18204	49	NRXN1,GPM6A
4.027e-02	-3.21	postsynaptic density, intracellular component	cellular component	GO:0099092	16	1	19108	49	TNIK
4.035e-02	-3.21	CNTNAP2 (contactin associated protein 2)	protein interactions	26047	16	1	19454	50	CPE
4.035e-02	-3.21	CYP2C8 (cytochrome P450 family 2 subfamily C member 8)	protein interactions	1558	16	1	19454	50	APOE
4.035e-02	-3.21	SYT9 (synaptotagmin 9)	protein interactions	143425	16	1	19454	50	NRXN1
4.035e-02	-3.21	HLA-H (major histocompatibility complex, class I, H (pseudogene))	protein interactions	3136	16	1	19454	50	FGFR3
4.035e-02	-3.21	FNDC8 (fibronectin type III domain containing 8)	protein interactions	54752	16	1	19454	50	SPARCL1
4.035e-02	-3.21	TWIST2 (twist family bHLH transcription factor 2)	protein interactions	117581	16	1	19454	50	ZBTB20
4.035e-02	-3.21	FZD4 (frizzled class receptor 4)	protein interactions	8322	16	1	19454	50	ZNRF3
4.035e-02	-3.21	SYT4 (synaptotagmin 4)	protein interactions	6860	16	1	19454	50	NRXN1
4.035e-02	-3.21	CDH12 (cadherin 12)	protein interactions	1010	16	1	19454	50	CTNNA2
4.035e-02	-3.21	SAPCD1 (suppressor APC domain containing 1)	protein interactions	401251	16	1	19454	50	CTNNA2
4.035e-02	-3.21	CTSK (cathepsin K)	protein interactions	1513	16	1	19454	50	FGFR3
4.035e-02	-3.21	SYTL2 (synaptotagmin like 2)	protein interactions	54843	16	1	19454	50	NRXN1
4.035e-02	-3.21	GALNT13 (polypeptide N-acetylgalactosaminyltransferase 13)	protein interactions	114805	16	1	19454	50	TNIK
4.054e-02	-3.21	Wnt signaling pathway	biological process	GO:0016055	283	3	18204	49	CPE,TNIK,ZNRF3
4.065e-02	-3.20	membrane protein complex	cellular component	GO:0098796	1261	7	19108	49	ATP1A2,CDH20,BMPR1B,SLC1A3,RYR3,SLC1A2,CTNNA2
4.066e-02	-3.20	kidney-carcinoma-papillary_renal_cell_carcinoma	COSMIC cancer mutations	kidney-carcinoma-papillary_renal_cell_carcinoma	6364	25	16828	49	PITPNC1,PREX2,CPE,PAMR1,ATP1A2,CLU,SLC4A4,NRXN1,NTM,MAML2,ZNRF3,ATP13A4,FGFR3,PTPRZ1,PON2,BMPR1B,GLUL,NFIA,ZBTB20,GPC5,SOX5,RYR3,HPSE2,TNIK,RORA
4.066e-02	-3.20	papillary_renal_cell_carcinoma	COSMIC cancer mutations	papillary_renal_cell_carcinoma	6364	25	16828	49	FGFR3,ZNRF3,ATP13A4,MAML2,NTM,NRXN1,PAMR1,CPE,SLC4A4,ATP1A2,CLU,PITPNC1,PREX2,RORA,HPSE2,TNIK,RYR3,SOX5,NFIA,GPC5,ZBTB20,BMPR1B,GLUL,PON2,PTPRZ1
4.078e-02	-3.20	oxysterol binding	molecular function	GO:0008142	16	1	18094	47	RORA
4.078e-02	-3.20	misfolded protein binding	molecular function	GO:0051787	16	1	18094	47	CLU
4.079e-02	-3.20	urinary_tract-bladder-carcinoma-transitional_cell_carcinoma	COSMIC cancer mutations	urinary_tract-bladder-carcinoma-transitional_cell_carcinoma	6040	24	16828	49	COL5A3,PTPRZ1,PON2,SPARCL1,HPSE2,NFIA,ZBTB20,GPC5,GPM6A,DTNA,PARD3B,CLU,ATP1A2,SLC4A4,PREX2,SLC1A3,CDH20,ATP13A4,FGFR3,PCDH9,HIF3A,TRPS1,NRXN1,GLIS3
4.081e-02	-3.20	Circadian rythm related genes	WikiPathways	WP3594	207	3	5310	20	PTGDS,RORA,CST3
4.095e-02	-3.20	transitional_cell_carcinoma	COSMIC cancer mutations	transitional_cell_carcinoma	6042	24	16828	49	PON2,PTPRZ1,COL5A3,NFIA,DTNA,GPM6A,GPC5,ZBTB20,SPARCL1,HPSE2,CDH20,PREX2,SLC1A3,SLC4A4,CLU,ATP1A2,PARD3B,TRPS1,HIF3A,GLIS3,NRXN1,FGFR3,PCDH9,ATP13A4
4.101e-02	-3.19	Ig-like_dom_sf	interpro domains	IPR036179	483	4	18521	50	LSAMP,NTM,HEPACAM,FGFR3
4.118e-02	-3.19	skin-extremity-malignant_melanoma	COSMIC cancer mutations	skin-extremity-malignant_melanoma	1875	10	16828	49	COL5A3,ATP13A4,PCDH9,HPSE2,RYR3,PITPNC1,FBXL7,CDH20,PREX2,PTPRZ1
4.126e-02	-3.19	cell junction assembly	biological process	GO:0034329	285	3	18204	49	NRXN1,GPM6A,CDH20
4.134e-02	-3.19	CNH	pfam domains	PF00780	15	1	17795	50	TNIK
4.134e-02	-3.19	Cation_ATPase_C	pfam domains	PF00689	15	1	17795	50	ATP1A2
4.166e-02	-3.18	SYP (synaptophysin)	protein interactions	6855	126	2	19454	50	GPM6A,PITPNC1
4.166e-02	-3.18	RNF115 (ring finger protein 115)	protein interactions	27246	126	2	19454	50	CST3,GLUL
4.171e-02	-3.18	central_nervous_system-brain-primitive_neuroectodermal_tumour-medulloblastoma-large_cell	COSMIC cancer mutations	central_nervous_system-brain-primitive_neuroectodermal_tumour-medulloblastoma-large_cell	1117	7	16828	49	GPC5,CDH20,SLC1A2,SOX5,RYR3,ATP13A4,QKI
4.196e-02	-3.17	ductolobular_carcinoma	COSMIC cancer mutations	ductolobular_carcinoma	1619	9	16828	49	PTPRZ1,PREX2,DTNA,CDH20,PARD3B,RORA,FGFR3,CPE,QKI
4.196e-02	-3.17	breast-carcinoma-ductolobular_carcinoma	COSMIC cancer mutations	breast-carcinoma-ductolobular_carcinoma	1619	9	16828	49	PARD3B,FGFR3,RORA,QKI,CPE,PREX2,PTPRZ1,CDH20,DTNA
4.221e-02	-3.17	COLFI	smart domains	SM00038	11	1	9717	38	COL5A3
4.223e-02	-3.16	asymmetric cell division	biological process	GO:0008356	16	1	18204	49	SOX5
4.223e-02	-3.16	insulin metabolic process	biological process	GO:1901142	16	1	18204	49	CPE
4.223e-02	-3.16	low-density lipoprotein particle remodeling	biological process	GO:0034374	16	1	18204	49	APOE
4.223e-02	-3.16	non-proteinogenic amino acid biosynthetic process	biological process	GO:0170043	16	1	18204	49	SLC1A3
4.223e-02	-3.16	neuron cell-cell adhesion	biological process	GO:0007158	16	1	18204	49	NRXN1
4.223e-02	-3.16	regulation of respiratory system process	biological process	GO:0044065	16	1	18204	49	ATP1A2
4.223e-02	-3.16	glutamine family amino acid biosynthetic process	biological process	GO:0009084	16	1	18204	49	GLUL
4.223e-02	-3.16	regulation of amino acid transmembrane transport	biological process	GO:1903789	16	1	18204	49	ATP1A2
4.223e-02	-3.16	cardiac left ventricle morphogenesis	biological process	GO:0003214	16	1	18204	49	CPE
4.223e-02	-3.16	positive regulation of membrane protein ectodomain proteolysis	biological process	GO:0051044	16	1	18204	49	APOE
4.223e-02	-3.16	S-adenosylmethionine metabolic process	biological process	GO:0046500	16	1	18204	49	AHCYL2
4.223e-02	-3.16	nonribosomal peptide biosynthetic process	biological process	GO:0019184	16	1	18204	49	SLC1A2
4.223e-02	-3.16	regulation of Wnt signaling pathway, planar cell polarity pathway	biological process	GO:2000095	16	1	18204	49	ZNRF3
4.223e-02	-3.16	regulation of amino acid import across plasma membrane	biological process	GO:0010958	16	1	18204	49	ATP1A2
4.235e-02	-3.16	CarboxyPept-like_regulatory	interpro domains	IPR008969	16	1	18521	50	CPE
4.242e-02	-3.16	inorganic ion transmembrane transport	biological process	GO:0098660	715	5	18204	49	GPM6A,SLC1A3,RYR3,SLC4A4,ATP1A2
4.270e-02	-3.15	lipoprotein metabolic process	biological process	GO:0042157	122	2	18204	49	GLUL,APOE
4.273e-02	-3.15	apical dendrite	cellular component	GO:0097440	17	1	19108	49	CLU
4.282e-02	-3.15	hypothalamus	COSMIC cancer mutations	hypothalamus	15	1	16828	49	QKI
4.282e-02	-3.15	ureter	COSMIC cancer mutations	ureter	15	1	16828	49	FGFR3
4.282e-02	-3.15	Pef1 (penta-EF hand domain containing 1)	protein interactions	67898	17	1	19454	50	QKI
4.282e-02	-3.15	MSANTD2 (Myb/SANT DNA binding domain containing 2)	protein interactions	79684	17	1	19454	50	SOX5
4.282e-02	-3.15	Shcbp1 (Shc SH2-domain binding protein 1)	protein interactions	20419	17	1	19454	50	GPC5
4.282e-02	-3.15	C16orf92 (chromosome 16 open reading frame 92)	protein interactions	146378	17	1	19454	50	APOE
4.282e-02	-3.15	DPP6 (dipeptidyl peptidase like 6)	protein interactions	1804	17	1	19454	50	GPM6A
4.282e-02	-3.15	PAX4 (paired box 4)	protein interactions	5078	17	1	19454	50	NTM
4.282e-02	-3.15	Sqstm1 (sequestosome 1)	protein interactions	18412	17	1	19454	50	BMPR1B
4.282e-02	-3.15	RASL12 (RAS like family 12)	protein interactions	51285	17	1	19454	50	BMPR1B
4.282e-02	-3.15	TAGAP (T cell activation RhoGTPase activating protein)	protein interactions	117289	17	1	19454	50	DTNA
4.282e-02	-3.15	NOTCH4 (notch receptor 4)	protein interactions	4855	17	1	19454	50	MAML2
4.286e-02	-3.15	SYT2 (synaptotagmin 2)	protein interactions	127833	128	2	19454	50	AHCYL2,NRXN1
4.286e-02	-3.15	TEAD2 (TEA domain transcription factor 2)	protein interactions	8463	128	2	19454	50	TRPS1,ZBTB20
4.286e-02	-3.15	MYB (MYB proto-oncogene, transcription factor)	protein interactions	4602	128	2	19454	50	TRPS1,NFIA
4.321e-02	-3.14	CARM1 (coactivator associated arginine methyltransferase 1)	protein interactions	10498	304	3	19454	50	QKI,RORA,DTNA
4.327e-02	-3.14	transmembrane receptor protein tyrosine phosphatase activity	molecular function	GO:0005001	17	1	18094	47	PTPRZ1
4.327e-02	-3.14	transmembrane receptor protein phosphatase activity	molecular function	GO:0019198	17	1	18094	47	PTPRZ1
4.346e-02	-3.14	POLA2 (DNA polymerase alpha 2, accessory subunit)	protein interactions	23649	129	2	19454	50	FGFR3,CPE
4.346e-02	-3.14	CHD7 (chromodomain helicase DNA binding protein 7)	protein interactions	55636	129	2	19454	50	SOX5,ZBTB20
4.350e-02	-3.13	modulation of chemical synaptic transmission	biological process	GO:0050804	494	4	18204	49	ATP1A2,APOE,SLC1A3,NRXN1
4.350e-02	-3.13	cellular response to growth factor stimulus	biological process	GO:0071363	494	4	18204	49	BMPR1B,NFIA,FGFR3,SOX5
4.362e-02	-3.13	bone-extraskeletal-Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour	COSMIC cancer mutations	bone-extraskeletal-Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour	891	6	16828	49	ATP1A2,FGFR3,PTGDS,SPARCL1,PTPRZ1,NPAS3
4.377e-02	-3.13	regulation of trans-synaptic signaling	biological process	GO:0099177	495	4	18204	49	NRXN1,SLC1A3,APOE,ATP1A2
4.391e-02	-3.13	CARBOXYPEPT_ZN_1	prosite domains	PS00132	13	1	12186	42	CPE
4.391e-02	-3.13	CARBOXYPEPT_ZN_2	prosite domains	PS00133	13	1	12186	42	CPE
4.397e-02	-3.12	positive regulation of lipid metabolic process	biological process	GO:0045834	124	2	18204	49	ZBTB20,APOE
4.407e-02	-3.12	RSPH1 (radial spoke head component 1)	protein interactions	89765	130	2	19454	50	GLUL,CLU
4.410e-02	-3.12	sequence-specific double-stranded DNA binding	molecular function	GO:1990837	1547	8	18094	47	TRPS1,SOX5,NPAS3,NFIA,GLIS3,HIF3A,RORA,ZBTB20
4.424e-02	-3.12	Ig-like_fold	interpro domains	IPR013783	721	5	18521	50	LSAMP,NTM,HEPACAM,PTPRZ1,FGFR3
4.430e-02	-3.12	Synthesis of Prostaglandins (PG) and Thromboxanes (TX)	REACTOME pathways	R-HSA-2162123	15	1	10285	31	PTGDS
4.432e-02	-3.12	MFAP5-mediated ovarian cancer cell motility and invasiveness	WikiPathways	WP3301	12	1	5310	20	RYR3
4.432e-02	-3.12	Bone Morphogenic Protein (BMP) Signalling and Regulation	WikiPathways	WP1425	12	1	5310	20	BMPR1B
4.437e-02	-3.12	brain development	biological process	GO:0007420	724	5	18204	49	CTNNA2,ATP1A2,SLC1A2,RORA,PCDH9
4.467e-02	-3.11	regulation of cellular process	biological process	GO:0050794	11468	37	18204	49	SLC1A2,RORA,TNIK,MAML2,DTNA,MSI2,CLU,SPARCL1,GLUL,GPC5,PTGDS,SOX5,PITPNC1,NFIA,APOE,SLC4A4,FGFR3,NPAS3,RYR3,PTPRZ1,QKI,GLIS3,HPSE2,BMPR1B,ZNRF3,GPM6A,TRPS1,CPE,PREX2,ZBTB20,SLC1A3,ATP1A2,CTNNA2,HIF3A,NRXN1,HEPACAM,CST3
4.468e-02	-3.11	ZNF609 (zinc finger protein 609)	protein interactions	23060	131	2	19454	50	NFIA,SOX5
4.468e-02	-3.11	TRPS1 (transcriptional repressor GATA binding 1)	protein interactions	7227	131	2	19454	50	SOX5,NFIA
4.468e-02	-3.11	NCOA2 (nuclear receptor coactivator 2)	protein interactions	10499	131	2	19454	50	RORA,NFIA
4.472e-02	-3.11	middle_lobe	COSMIC cancer mutations	middle_lobe	1382	8	16828	49	ATP13A4,FGFR3,PCDH9,PARD3B,HPSE2,ATP1A2,RYR3,CPE
4.477e-02	-3.11	Helix-loop-helix DNA-binding domain	gene3d domains	4.10.280.10	111	2	14470	44	NPAS3,HIF3A
4.481e-02	-3.11	cell migration in hindbrain	biological process	GO:0021535	17	1	18204	49	CTNNA2
4.481e-02	-3.11	protein trimerization	biological process	GO:0070206	17	1	18204	49	SLC1A2
4.481e-02	-3.11	cellular response to ATP	biological process	GO:0071318	17	1	18204	49	RYR3
4.481e-02	-3.11	high-density lipoprotein particle remodeling	biological process	GO:0034375	17	1	18204	49	APOE
4.481e-02	-3.11	membrane depolarization during cardiac muscle cell action potential	biological process	GO:0086012	17	1	18204	49	ATP1A2
4.481e-02	-3.11	viral genome replication	biological process	GO:0019079	17	1	18204	49	NFIA
4.481e-02	-3.11	T-helper 17 type immune response	biological process	GO:0072538	17	1	18204	49	RORA
4.481e-02	-3.11	cGMP metabolic process	biological process	GO:0046068	17	1	18204	49	RORA
4.481e-02	-3.11	positive regulation of vascular permeability	biological process	GO:0043117	17	1	18204	49	APOE
4.481e-02	-3.11	negative regulation of triglyceride metabolic process	biological process	GO:0090209	17	1	18204	49	APOE
4.481e-02	-3.11	cell communication by electrical coupling involved in cardiac conduction	biological process	GO:0086064	17	1	18204	49	ATP1A2
4.481e-02	-3.11	ureter development	biological process	GO:0072189	17	1	18204	49	NFIA
4.481e-02	-3.11	fatty acid homeostasis	biological process	GO:0055089	17	1	18204	49	APOE
4.481e-02	-3.11	regulation of inclusion body assembly	biological process	GO:0090083	17	1	18204	49	CLU
4.481e-02	-3.11	microvillus assembly	biological process	GO:0030033	17	1	18204	49	TNIK
4.493e-02	-3.10	PAC	interpro domains	IPR001610	17	1	18521	50	HIF3A
4.493e-02	-3.10	Cystatin_dom	interpro domains	IPR000010	17	1	18521	50	CST3
4.493e-02	-3.10	CA_dom_sf	interpro domains	IPR036398	17	1	18521	50	PTPRZ1
4.493e-02	-3.10	CA_dom	interpro domains	IPR001148	17	1	18521	50	PTPRZ1
4.507e-02	-3.10	ductal_carcinoma	COSMIC cancer mutations	ductal_carcinoma	15798	49	16828	49	NRXN1,GLIS3,MAML2,PTGDS,ZNRF3,PCDH9,PREX2,SLC1A3,PARD3B,CPE,APOE,ZBTB20,GPC5,GPM6A,NFIA,TNIK,RYR3,HPSE2,RORA,QKI,PTPRZ1,NPAS3,SLC1A2,NKAIN3,GLUL,BMPR1B,HIF3A,HEPACAM,TRPS1,NTM,ATP13A4,FGFR3,NHSL1,CDH20,PITPNC1,ATP1A2,CLU,SLC4A4,AHCYL2,LSAMP,PAMR1,MSI2,DTNA,CST3,FBXL7,SOX5,SPARCL1,PON2,COL5A3
4.529e-02	-3.09	Tgfbr1 (transforming growth factor, beta receptor I)	protein interactions	21812	18	1	19454	50	BMPR1B
4.529e-02	-3.09	OPCML (opioid binding protein/cell adhesion molecule like)	protein interactions	4978	18	1	19454	50	NTM
4.529e-02	-3.09	KLHL1 (kelch like family member 1)	protein interactions	57626	18	1	19454	50	BMPR1B
4.529e-02	-3.09	Lck (lymphocyte protein tyrosine kinase)	protein interactions	16818	18	1	19454	50	APOE
4.529e-02	-3.09	PTGFR (prostaglandin F receptor)	protein interactions	5737	18	1	19454	50	PTGDS
4.529e-02	-3.09	CYP2E1 (cytochrome P450 family 2 subfamily E member 1)	protein interactions	1571	18	1	19454	50	CLU
4.529e-02	-3.09	NKIRAS1 (NFKB inhibitor interacting Ras like 1)	protein interactions	28512	18	1	19454	50	BMPR1B
4.529e-02	-3.09	NECTIN1 (nectin cell adhesion molecule 1)	protein interactions	5818	18	1	19454	50	FGFR3
4.530e-02	-3.09	GPIHBP1 (glycosylphosphatidylinositol anchored high density lipoprotein binding protein 1)	protein interactions	338328	132	2	19454	50	CPE,FGFR3
4.531e-02	-3.09	positive regulation of nervous system development	biological process	GO:0051962	296	3	18204	49	NRXN1,QKI,PTPRZ1
4.535e-02	-3.09	C11orf52 (chromosome 11 open reading frame 52)	protein interactions	91894	310	3	19454	50	AHCYL2,TNIK,DTNA
4.561e-02	-3.09	normal	COSMIC cancer mutations	normal	16	1	16828	49	FGFR3
4.561e-02	-3.09	renal_pelvis	COSMIC cancer mutations	renal_pelvis	16	1	16828	49	FGFR3
4.561e-02	-3.09	urinary_tract-carcinoma	COSMIC cancer mutations	urinary_tract-carcinoma	16	1	16828	49	FGFR3
4.561e-02	-3.09	flank	COSMIC cancer mutations	flank	16	1	16828	49	FGFR3
4.569e-02	-3.09	muscle system process	biological process	GO:0003012	297	3	18204	49	ATP1A2,RYR3,DTNA
4.569e-02	-3.09	carboxylic acid transport	biological process	GO:0046942	297	3	18204	49	SLC1A3,SLC1A2,APOE
4.576e-02	-3.08	phosphatidylcholine transporter activity	molecular function	GO:0008525	18	1	18094	47	PITPNC1
4.576e-02	-3.08	intracellularly gated calcium channel activity	molecular function	GO:0015278	18	1	18094	47	RYR3
4.596e-02	-3.08	DWA	smart domains	SM00523	12	1	9717	38	NFIA
4.596e-02	-3.08	ZnF_GATA	smart domains	SM00401	12	1	9717	38	TRPS1
4.606e-02	-3.08	extraskeletal	COSMIC cancer mutations	extraskeletal	903	6	16828	49	SPARCL1,ATP1A2,PTGDS,FGFR3,PTPRZ1,NPAS3
4.607e-02	-3.08	organic acid transport	biological process	GO:0015849	298	3	18204	49	SLC1A3,APOE,SLC1A2
4.613e-02	-3.08	PDZ	pfam domains	PF00595	122	2	17795	50	PARD3B,PREX2
4.629e-02	-3.07	Hypoxic and oxygen homeostasis regulation of HIF-1-alpha	Pathway Interaction DB	hif1apathway	15	1	2226	7	HIF3A
4.655e-02	-3.07	myelination	biological process	GO:0042552	128	2	18204	49	CLU,QKI
4.673e-02	-3.06	ZZ	pfam domains	PF00569	17	1	17795	50	DTNA
4.673e-02	-3.06	Cystatin	pfam domains	PF00031	17	1	17795	50	CST3
4.673e-02	-3.06	Carb_anhydrase	pfam domains	PF00194	17	1	17795	50	PTPRZ1
4.674e-02	-3.06	GRB2 (growth factor receptor bound protein 2)	protein interactions	2885	769	5	19454	50	CLU,PON2,MSI2,SLC1A2,FGFR3
4.676e-02	-3.06	protein-folding chaperone binding	molecular function	GO:0051087	133	2	18094	47	CLU,ATP1A2
4.696e-02	-3.06	Cadherins	gene3d domains	2.60.40.60	114	2	14470	44	CDH20,PCDH9
4.716e-02	-3.05	BMP4 (bone morphogenetic protein 4)	protein interactions	652	135	2	19454	50	BMPR1B,CLU
4.716e-02	-3.05	FOXP1 (forkhead box P1)	protein interactions	27086	135	2	19454	50	NFIA,SOX5
4.716e-02	-3.05	SOX15 (SRY-box transcription factor 15)	protein interactions	6665	135	2	19454	50	TRPS1,NFIA
4.722e-02	-3.05	central_nervous_system-brain-glioma-astrocytoma_Grade_IV	COSMIC cancer mutations	central_nervous_system-brain-glioma-astrocytoma_Grade_IV	15813	49	16828	49	ATP13A4,FGFR3,NTM,HEPACAM,TRPS1,HIF3A,PAMR1,LSAMP,SLC4A4,AHCYL2,CLU,ATP1A2,PITPNC1,NHSL1,CDH20,SPARCL1,SOX5,FBXL7,CST3,DTNA,MSI2,COL5A3,PON2,PTGDS,ZNRF3,PCDH9,MAML2,GLIS3,NRXN1,CPE,APOE,PARD3B,SLC1A3,PREX2,QKI,RORA,HPSE2,RYR3,TNIK,NFIA,GPM6A,ZBTB20,GPC5,BMPR1B,GLUL,NKAIN3,NPAS3,SLC1A2,PTPRZ1
4.738e-02	-3.05	dicarboxylic acid catabolic process	biological process	GO:0043649	18	1	18204	49	GLUL
4.738e-02	-3.05	negative regulation of sodium ion transport	biological process	GO:0010766	18	1	18204	49	ATP1A2
4.738e-02	-3.05	regulation of extracellular matrix disassembly	biological process	GO:0010715	18	1	18204	49	CST3
4.738e-02	-3.05	myelin maintenance	biological process	GO:0043217	18	1	18204	49	CLU
4.738e-02	-3.05	response to misfolded protein	biological process	GO:0051788	18	1	18204	49	CLU
4.738e-02	-3.05	positive regulation of circadian rhythm	biological process	GO:0042753	18	1	18204	49	RORA
4.738e-02	-3.05	receptor catabolic process	biological process	GO:0032801	18	1	18204	49	ZNRF3
4.738e-02	-3.05	negative regulation of platelet activation	biological process	GO:0010544	18	1	18204	49	APOE
4.752e-02	-3.05	Leu-rich_rpt_Cys-con_subtyp	interpro domains	IPR006553	18	1	18521	50	FBXL7
4.764e-02	-3.04	cation-transporting ATPase complex	cellular component	GO:0090533	19	1	19108	49	ATP1A2
4.764e-02	-3.04	astrocyte projection	cellular component	GO:0097449	19	1	19108	49	SLC1A2
4.764e-02	-3.04	postsynaptic specialization, intracellular component	cellular component	GO:0099091	19	1	19108	49	TNIK
4.764e-02	-3.04	parallel fiber to Purkinje cell synapse	cellular component	GO:0098688	19	1	19108	49	GPM6A
4.774e-02	-3.04	SYT7 (synaptotagmin 7)	protein interactions	9066	19	1	19454	50	NRXN1
4.774e-02	-3.04	RIT2 (Ras like without CAAX 2)	protein interactions	6014	19	1	19454	50	DTNA
4.774e-02	-3.04	SPZ1 (spermatogenic leucine zipper 1)	protein interactions	84654	19	1	19454	50	DTNA
4.774e-02	-3.04	PHYHIPL (phytanoyl-CoA 2-hydroxylase interacting protein like)	protein interactions	84457	19	1	19454	50	GPM6A
4.774e-02	-3.04	NLGN1 (neuroligin 1)	protein interactions	22871	19	1	19454	50	NRXN1
4.774e-02	-3.04	TNR (tenascin R)	protein interactions	7143	19	1	19454	50	PTPRZ1
4.774e-02	-3.04	C3orf62 (chromosome 3 open reading frame 62)	protein interactions	375341	19	1	19454	50	ATP1A2
4.774e-02	-3.04	FBXO27 (F-box protein 27)	protein interactions	126433	19	1	19454	50	CLU
4.774e-02	-3.04	INKA1 (inka box actin regulator 1)	protein interactions	389119	19	1	19454	50	ZBTB20
4.786e-02	-3.04	axon ensheathment	biological process	GO:0008366	130	2	18204	49	CLU,QKI
4.786e-02	-3.04	ensheathment of neurons	biological process	GO:0007272	130	2	18204	49	QKI,CLU
4.793e-02	-3.04	Cell-type Dependent Selectivity of CCK2R Signaling	WikiPathways	WP3679	13	1	5310	20	RYR3
4.793e-02	-3.04	skin-back-malignant_melanoma	COSMIC cancer mutations	skin-back-malignant_melanoma	280	3	16828	49	PREX2,ATP1A2,TNIK
4.824e-02	-3.03	transmembrane receptor protein serine/threonine kinase activity	molecular function	GO:0004675	19	1	18094	47	BMPR1B
4.824e-02	-3.03	alkali metal ion binding	molecular function	GO:0031420	19	1	18094	47	ATP1A2
4.839e-02	-3.03	skin-carcinoma-squamous_cell_carcinoma_BRAF_inhibitor_related	COSMIC cancer mutations	skin-carcinoma-squamous_cell_carcinoma_BRAF_inhibitor_related	17	1	16828	49	FGFR3
4.839e-02	-3.03	verrucal_keratosis_BRAF_inhibitor_related	COSMIC cancer mutations	verrucal_keratosis_BRAF_inhibitor_related	17	1	16828	49	FGFR3
4.839e-02	-3.03	non_chronically_sun_exposed_site	COSMIC cancer mutations	non_chronically_sun_exposed_site	17	1	16828	49	FGFR3
4.839e-02	-3.03	skin-other-verrucal_keratosis_BRAF_inhibitor_related	COSMIC cancer mutations	skin-other-verrucal_keratosis_BRAF_inhibitor_related	17	1	16828	49	FGFR3
4.839e-02	-3.03	squamous_cell_carcinoma_BRAF_inhibitor_related	COSMIC cancer mutations	squamous_cell_carcinoma_BRAF_inhibitor_related	17	1	16828	49	FGFR3
4.839e-02	-3.03	optic_nerve	COSMIC cancer mutations	optic_nerve	17	1	16828	49	QKI
4.839e-02	-3.03	central_nervous_system-optic_nerve-glioma-astrocytoma_Grade_I	COSMIC cancer mutations	central_nervous_system-optic_nerve-glioma-astrocytoma_Grade_I	17	1	16828	49	QKI
4.839e-02	-3.03	skin-non_chronically_sun_exposed_site-malignant_melanoma	COSMIC cancer mutations	skin-non_chronically_sun_exposed_site-malignant_melanoma	17	1	16828	49	FGFR3
4.839e-02	-3.03	breast-carcinoma-neuroendocrine_carcinoma	COSMIC cancer mutations	breast-carcinoma-neuroendocrine_carcinoma	17	1	16828	49	FGFR3
4.842e-02	-3.03	TBL1X (transducin beta like 1 X-linked)	protein interactions	6907	137	2	19454	50	NFIA,SOX5
4.852e-02	-3.03	carboxylic acid transmembrane transport	biological process	GO:1905039	131	2	18204	49	SLC1A3,SLC1A2
4.859e-02	-3.02	human chr18q12.1	chromosome location	human chr18q12.1	26	1	26134	50	DTNA
4.866e-02	-3.02	calcium ion transmembrane transporter activity	molecular function	GO:0015085	136	2	18094	47	GPM6A,RYR3
4.918e-02	-3.01	amino acid transport	biological process	GO:0006865	132	2	18204	49	SLC1A3,SLC1A2
4.946e-02	-3.01	EF-hand	gene3d domains	1.10.238.10	272	3	14470	44	RYR3,DTNA,SPARCL1
4.962e-02	-3.00	thalamus	COSMIC cancer mutations	thalamus	284	3	16828	49	FGFR3,DTNA,QKI
4.968e-02	-3.00	DUSP22 (dual specificity phosphatase 22)	protein interactions	56940	139	2	19454	50	QKI,CTNNA2
4.968e-02	-3.00	NEFM (neurofilament medium chain)	protein interactions	4741	139	2	19454	50	APOE,TNIK
4.985e-02	-3.00	regulation of sequestering of calcium ion	biological process	GO:0051282	133	2	18204	49	ATP1A2,RYR3
4.995e-02	-3.00	excitatory synapse assembly	biological process	GO:1904861	19	1	18204	49	NRXN1
4.995e-02	-3.00	response to potassium ion	biological process	GO:0035864	19	1	18204	49	ATP1A2
4.995e-02	-3.00	vocalization behavior	biological process	GO:0071625	19	1	18204	49	NRXN1
4.995e-02	-3.00	cerebellar Purkinje cell layer morphogenesis	biological process	GO:0021692	19	1	18204	49	RORA
4.995e-02	-3.00	vascular associated smooth muscle cell differentiation	biological process	GO:0035886	19	1	18204	49	QKI
4.995e-02	-3.00	negative regulation of alcohol biosynthetic process	biological process	GO:1902931	19	1	18204	49	APOE
4.995e-02	-3.00	microvillus organization	biological process	GO:0032528	19	1	18204	49	TNIK
4.995e-02	-3.00	regulation of circadian sleep/wake cycle	biological process	GO:0042749	19	1	18204	49	PTGDS
4.995e-02	-3.00	regulation of neurotransmitter uptake	biological process	GO:0051580	19	1	18204	49	ATP1A2