Gene Ontology Enrichment Results

Homer de novo Motif Enrichment Results
Known Motif Enrichment Results

Text file version of complete results (i.e. open with Excel)

biological process: Functional groupings of proteins (Gene Ontology)

molecular function: Mechanistic actions of proteins (Gene Ontology)

cellular component: Protein localization (Gene Ontology)

chromosome location: Genes with similar chromosome localization (NCBI Gene)

KEGG pathways: Groups of proteins in the same pathways (KEGG)

protein interactions: "Proteins interacting with a common protein (BIND, EcoCyc, HPRD)" (NCBI Gene)

interpro domains: Proteins with similar domains and features (Interpro)

pfam domains: Proteins with similar domains and features (Pfam)

smart domains: Proteins with similar domains and features (SMART)

gene3d domains: Proteins with similar domains and features (Gene3D)

prosite domains: Proteins with similar domains and features (Prosite)

prints domains: Proteins with similar domains and features (PRINTS)

MSigDB lists: "Genes sets for pathways, factor/miRNA target predictions, expression patterns, etc." (MSigDB)

BIOCYC pathways: Groups of proteins in the same pathways (BIOCYC)

COSMIC cancer mutations: Genes mutated in similar cancers (COSMIC)

GWAS genes: Genes mutated in similar diseases (GWAS Catalog)

Lipid Maps pathways: Groups of proteins in the same lipid pathways (Lipid Maps/Biosystems)

Pathway Interaction DB: Groups of proteins in the same pathways (Pathway Interaction Database)

REACTOME pathways: Groups of proteins in the same pathways (REACTOME)

SMPDB pathways: Groups of proteins in the same pathways (SMPDB)

WikiPathways: Groups of proteins in the same pathways (Wikipathways)

Enriched Categories

P-value	ln(P)	Term	GO Tree	GO ID	# of Genes in Term	# of Target Genes in Term	# of Total Genes	# of Target Genes	Common Genes
5.813e-13	-28.17	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-acute_lymphoblastic_B_cell_leukaemia	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-acute_lymphoblastic_B_cell_leukaemia	3828	35	16828	49	CTNND2,ADCY2,PTPRZ1,NTM,GPM6A,LSAMP,TNIK,CPE,PCDH9,SLC1A2,NKAIN3,GLIS3,PRKG1,CSGALNACT1,FBXL7,COL5A3,ZBTB20,SLC1A3,NRXN1,NFIA,GPC5,ITPR2,ATP13A4,MGAT4C,HPSE2,GABRB1,SOX5,FMN2,BMPR1B,RORA,PREX2,LRP1B,NTRK2,CADM1,NRG3
5.813e-13	-28.17	acute_lymphoblastic_B_cell_leukaemia	COSMIC cancer mutations	acute_lymphoblastic_B_cell_leukaemia	3828	35	16828	49	FMN2,RORA,BMPR1B,NTRK2,CADM1,LRP1B,NRG3,PREX2,HPSE2,MGAT4C,ATP13A4,GABRB1,SOX5,ITPR2,GPC5,NFIA,COL5A3,NRXN1,ZBTB20,SLC1A3,PRKG1,FBXL7,CSGALNACT1,SLC1A2,NKAIN3,GLIS3,PCDH9,CPE,PTPRZ1,GPM6A,NTM,TNIK,LSAMP,CTNND2,ADCY2
1.305e-12	-27.37	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-Burkitt_lymphoma	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-Burkitt_lymphoma	2119	27	16828	49	NPAS3,CSGALNACT1,PRKG1,FBXL7,NHSL1,NKAIN3,SLC1A2,GPM6A,LSAMP,PCDH9,CPE,ADCY2,CTNND2,PREX2,NTRK2,CADM1,LRP1B,NRG3,BMPR1B,FMN2,GABRB1,SOX5,ATP13A4,HPSE2,ITPR2,GPC5,SLC1A3
1.305e-12	-27.37	Burkitt_lymphoma	COSMIC cancer mutations	Burkitt_lymphoma	2119	27	16828	49	LRP1B,NTRK2,CADM1,NRG3,PREX2,FMN2,BMPR1B,GABRB1,SOX5,HPSE2,ATP13A4,GPC5,ITPR2,SLC1A3,FBXL7,CSGALNACT1,NPAS3,PRKG1,NHSL1,NKAIN3,SLC1A2,CPE,PCDH9,GPM6A,LSAMP,ADCY2,CTNND2
2.559e-11	-24.39	myelodysplastic_syndrome	COSMIC cancer mutations	myelodysplastic_syndrome	1174	20	16828	49	BMPR1B,FBXL7,NPAS3,PRKG1,NRG3,LRP1B,NTRK2,PREX2,FGFR3,HPSE2,SLC1A2,SOX5,GABRB1,NKAIN3,NFIA,ATP1A2,LSAMP,TNIK,COL5A3,ADCY2
2.559e-11	-24.39	haematopoietic_and_lymphoid_tissue-haematopoietic_neoplasm-myelodysplastic_syndrome	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue-haematopoietic_neoplasm-myelodysplastic_syndrome	1174	20	16828	49	ATP1A2,TNIK,LSAMP,NFIA,ADCY2,COL5A3,NRG3,NTRK2,LRP1B,PREX2,BMPR1B,FBXL7,PRKG1,NPAS3,SOX5,GABRB1,NKAIN3,HPSE2,FGFR3,SLC1A2
3.886e-11	-23.97	brainstem	COSMIC cancer mutations	brainstem	3102	30	16828	49	FBXL7,PRKG1,NPAS3,NKAIN3,FGFR3,SLC1A2,PCDH9,CPE,GPM6A,PTPRZ1,LSAMP,TNIK,ADCY2,RANBP3L,CDH20,CTNND2,CADM1,LRP1B,NRG3,PREX2,RORA,FMN2,GABRB1,SOX5,HPSE2,ATP13A4,ITPR2,GPC5,ZBTB20,SLC1A3
8.944e-11	-23.14	central_nervous_system-brainstem-glioma-astrocytoma_Grade_IV	COSMIC cancer mutations	central_nervous_system-brainstem-glioma-astrocytoma_Grade_IV	2531	27	16828	49	NKAIN3,PRKG1,FBXL7,CTNND2,CDH20,RANBP3L,ADCY2,LSAMP,TNIK,PTPRZ1,GPM6A,CPE,PCDH9,ATP13A4,HPSE2,SOX5,GABRB1,RORA,FMN2,PREX2,NRG3,CADM1,LRP1B,SLC1A3,ZBTB20,GPC5,ITPR2
2.105e-10	-22.28	blood_vessel	COSMIC cancer mutations	blood_vessel	2211	25	16828	49	NKAIN3,FGFR3,SLC1A2,PRKG1,FBXL7,ADCY2,CDH20,CTNND2,PCDH9,LSAMP,GPM6A,PTPRZ1,SOX5,GABRB1,HPSE2,NRG3,CADM1,NTRK2,LRP1B,PREX2,FMN2,SLC1A3,COL5A3,GPC5,ITPR2
2.292e-10	-22.20	haematopoietic_and_lymphoid_tissue-haematopoietic_neoplasm	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue-haematopoietic_neoplasm	764	16	16828	49	GPC5,ATP1A2,LSAMP,PCDH9,COL5A3,ADCY2,FBXL7,PREX2,NTRK2,LRP1B,NRG3,SLC1A2,HPSE2,NKAIN3,GABRB1,SOX5
2.522e-10	-22.10	cerebellum	COSMIC cancer mutations	cerebellum	769	16	16828	49	NPAS3,PRKG1,NRG3,CADM1,NTRK2,LRP1B,HPSE2,GABRB1,GPC5,ITPR2,CPE,PCDH9,PTPRZ1,CTNND2,NRXN1,ABLIM1
2.685e-10	-22.04	central_nervous_system-cerebellum-primitive_neuroectodermal_tumour-medulloblastoma-SHH_subtype	COSMIC cancer mutations	central_nervous_system-cerebellum-primitive_neuroectodermal_tumour-medulloblastoma-SHH_subtype	653	15	16828	49	ITPR2,PTPRZ1,CPE,PCDH9,CTNND2,NRXN1,ABLIM1,NPAS3,PRKG1,NRG3,CADM1,LRP1B,NTRK2,HPSE2,GABRB1
2.743e-10	-22.02	SHH_subtype	COSMIC cancer mutations	SHH_subtype	654	15	16828	49	PTPRZ1,CPE,PCDH9,ITPR2,NRXN1,ABLIM1,CTNND2,NRG3,NTRK2,LRP1B,CADM1,PRKG1,NPAS3,GABRB1,HPSE2
3.507e-10	-21.77	acute_myeloid_leukaemia_therapy_related	COSMIC cancer mutations	acute_myeloid_leukaemia_therapy_related	1523	21	16828	49	ITPR2,GPC5,LSAMP,PCDH9,CTNND2,COL5A3,SLC1A3,ADCY2,PRKG1,FBXL7,RORA,FMN2,PREX2,NTRK2,CADM1,LRP1B,NRG3,HPSE2,NKAIN3,GABRB1,SOX5
3.507e-10	-21.77	haematopoietic_and_lymphoid_tissue-haematopoietic_neoplasm-acute_myeloid_leukaemia_therapy_related	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue-haematopoietic_neoplasm-acute_myeloid_leukaemia_therapy_related	1523	21	16828	49	SLC1A3,ADCY2,CTNND2,COL5A3,LSAMP,PCDH9,GPC5,ITPR2,NKAIN3,GABRB1,SOX5,HPSE2,PREX2,CADM1,LRP1B,NTRK2,NRG3,PRKG1,FBXL7,FMN2,RORA
1.192e-09	-20.55	angiosarcoma	COSMIC cancer mutations	angiosarcoma	2192	24	16828	49	COL5A3,SLC1A3,ITPR2,GPC5,HPSE2,GABRB1,SOX5,FMN2,NTRK2,LRP1B,CADM1,NRG3,PREX2,CTNND2,ADCY2,CDH20,PCDH9,GPM6A,PTPRZ1,LSAMP,SLC1A2,NKAIN3,PRKG1,FBXL7
1.192e-09	-20.55	soft_tissue-blood_vessel-angiosarcoma	COSMIC cancer mutations	soft_tissue-blood_vessel-angiosarcoma	2192	24	16828	49	CDH20,ADCY2,CTNND2,LSAMP,GPM6A,PTPRZ1,PCDH9,NKAIN3,SLC1A2,FBXL7,PRKG1,SLC1A3,COL5A3,GPC5,ITPR2,SOX5,GABRB1,HPSE2,PREX2,NRG3,CADM1,NTRK2,LRP1B,FMN2
2.096e-09	-19.98	diffuse_large_B_cell_lymphoma	COSMIC cancer mutations	diffuse_large_B_cell_lymphoma	4151	32	16828	49	RORA,FMN2,PREX2,NRG3,NTRK2,LRP1B,DTNA,CADM1,ATP13A4,HPSE2,SOX5,GABRB1,GPC5,ITPR2,SPARCL1,SLC1A3,PRKG1,CSGALNACT1,FBXL7,SLC1A2,FGFR3,NKAIN3,LSAMP,ATP1A2,TNIK,GPM6A,CPE,PCDH9,CTNND2,CDH20,RANBP3L,ADCY2
2.639e-09	-19.75	chondroblastoma	COSMIC cancer mutations	chondroblastoma	534	13	16828	49	PRKG1,FMN2,LRP1B,NRG3,NKAIN3,GABRB1,SOX5,GPC5,GPM6A,LSAMP,PCDH9,CTNND2,ADCY2
9.721e-09	-18.45	nervous system development	biological process	GO:0007399	2185	22	18204	49	MSI2,SOX5,SLC1A2,RORA,GABRB1,GPM6A,SLC1A3,LSAMP,NRXN1,NTM,ATP1A2,CTNND2,BMPR1B,PTPRZ1,PRKG1,NFIA,PREX2,TNIK,PCDH9,NRG3,APOE,NTRK2
1.050e-08	-18.37	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-diffuse_large_B_cell_lymphoma	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-diffuse_large_B_cell_lymphoma	3608	29	16828	49	ITPR2,GPC5,SPARCL1,FMN2,RORA,NRG3,CADM1,LRP1B,PREX2,HPSE2,ATP13A4,SOX5,GABRB1,CPE,PCDH9,LSAMP,ATP1A2,TNIK,GPM6A,CTNND2,RANBP3L,ADCY2,CDH20,CSGALNACT1,FBXL7,PRKG1,FGFR3,SLC1A2,NKAIN3
2.943e-08	-17.34	generation of neurons	biological process	GO:0048699	1158	16	18204	49	NRXN1,TNIK,NTM,CTNND2,BMPR1B,APOE,NTRK2,SOX5,PRKG1,NFIA,PTPRZ1,SLC1A3,GABRB1,RORA,GPM6A,PREX2
2.998e-08	-17.32	system development	biological process	GO:0048731	3533	27	18204	49	CPE,NRG3,PCDH9,TNIK,APOE,NTRK2,PTPRZ1,NFIA,PRKG1,PREX2,LSAMP,NTM,ATP1A2,NRXN1,BMPR1B,CTNND2,RANBP3L,MSI2,SOX5,SLC1A2,CSGALNACT1,GPM6A,GABRB1,RORA,SLC1A3,FGFR3,CADM1
5.023e-08	-16.81	prostate-carcinoma	COSMIC cancer mutations	prostate-carcinoma	9000	44	16828	49	FGFR3,GLIS3,NKAIN3,NHSL1,NPAS3,PRKG1,FBXL7,CTNND2,ABLIM1,APOE,TNIK,LSAMP,NTM,HPSE2,MSI2,GABRB1,FMN2,NTRK2,LRP1B,DTNA,CADM1,PREX2,ZBTB20,GPC5,SLC1A2,CSGALNACT1,ADCY2,CDH20,CPE,PCDH9,GPM6A,PTPRZ1,ATP13A4,SOX5,BMPR1B,RORA,NRG3,COL5A3,SPARCL1,NRXN1,SLC1A3,ITPR2,PITPNC1,NFIA
5.657e-08	-16.69	cell periphery	cellular component	GO:0071944	6020	34	19108	49	NKAIN3,ATP13A4,LSAMP,APOE,FMN2,PRKG1,SLC1A3,FGFR3,NRXN1,COL5A3,CDH20,CTNND2,SLC1A2,ATP1A2,HPSE2,GPC5,PREX2,TNIK,NTRK2,PCDH9,CADM1,NRG3,ITPR2,ADCY2,CPE,DTNA,GPM6A,BMPR1B,SPARCL1,NTM,CST3,GABRB1,PTPRZ1,LRP1B
7.462e-08	-16.41	multicellular organism development	biological process	GO:0007275	3957	28	18204	49	CTNND2,BMPR1B,LSAMP,NRXN1,NTM,ATP1A2,RANBP3L,SLC1A2,MSI2,SOX5,CADM1,RORA,GABRB1,GPM6A,CSGALNACT1,FGFR3,SLC1A3,CPE,TNIK,NRG3,PCDH9,NTRK2,APOE,PTPRZ1,PRKG1,NFIA,CDH20,PREX2
8.526e-08	-16.28	neuron differentiation	biological process	GO:0030182	1081	15	18204	49	PREX2,GPM6A,GABRB1,RORA,SLC1A3,PTPRZ1,NFIA,PRKG1,NTRK2,APOE,BMPR1B,CTNND2,NTM,TNIK,NRXN1
9.120e-08	-16.21	haematopoietic_and_lymphoid_tissue-lymph_node-lymphoid_neoplasm-mantle_cell_lymphoma	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue-lymph_node-lymphoid_neoplasm-mantle_cell_lymphoma	476	11	16828	49	PRKG1,CADM1,LRP1B,NRG3,ATP13A4,GABRB1,GPC5,GPM6A,LSAMP,PCDH9,CTNND2
1.024e-07	-16.09	anatomical structure development	biological process	GO:0048856	5207	32	18204	49	PREX2,NFIA,PRKG1,PTPRZ1,CDH20,NTRK2,COL5A3,SPARCL1,APOE,PCDH9,NRG3,TNIK,CPE,CADM1,SLC1A3,FGFR3,GPM6A,CSGALNACT1,FMN2,RORA,GABRB1,SLC1A2,SOX5,MSI2,ABLIM1,RANBP3L,BMPR1B,CTNND2,NTM,ATP1A2,NRXN1,LSAMP
1.086e-07	-16.04	lymph_node	COSMIC cancer mutations	lymph_node	1703	19	16828	49	SOX5,GABRB1,FGFR3,ATP13A4,NRG3,DTNA,NTRK2,CADM1,LRP1B,PRKG1,RANBP3L,SLC1A3,CTNND2,PCDH9,TNIK,LSAMP,GPM6A,GPC5,ITPR2
1.437e-07	-15.76	plasma membrane	cellular component	GO:0005886	5538	32	19108	49	CADM1,PCDH9,NTRK2,TNIK,CPE,DTNA,ADCY2,ITPR2,NRG3,GPM6A,BMPR1B,NTM,CST3,PTPRZ1,LRP1B,GABRB1,NKAIN3,LSAMP,ATP13A4,FMN2,APOE,PRKG1,NRXN1,FGFR3,SLC1A3,CDH20,SLC1A2,CTNND2,PREX2,HPSE2,GPC5,ATP1A2
1.551e-07	-15.68	central_nervous_system-brain-primitive_neuroectodermal_tumour-medulloblastoma	COSMIC cancer mutations	central_nervous_system-brain-primitive_neuroectodermal_tumour-medulloblastoma	7205	39	16828	49	CSGALNACT1,PRKG1,FBXL7,NPAS3,NHSL1,FGFR3,SLC1A2,NKAIN3,GLIS3,PCDH9,CPE,PTPRZ1,GPM6A,NTM,LSAMP,TNIK,CTNND2,ADCY2,ABLIM1,RANBP3L,RORA,FMN2,NTRK2,LRP1B,CADM1,NRG3,PREX2,HPSE2,ATP13A4,GABRB1,SOX5,ITPR2,GPC5,NFIA,PITPNC1,COL5A3,NRXN1,ZBTB20,SLC1A3
1.584e-07	-15.66	follicular_lymphoma	COSMIC cancer mutations	follicular_lymphoma	1209	16	16828	49	SOX5,GABRB1,NKAIN3,HPSE2,NRG3,LRP1B,RORA,PRKG1,RANBP3L,ADCY2,CTNND2,PCDH9,TNIK,LSAMP,GPC5,ITPR2
1.824e-07	-15.52	bone-humerus-other-chondroblastoma	COSMIC cancer mutations	bone-humerus-other-chondroblastoma	301	9	16828	49	FMN2,PRKG1,GPC5,GPM6A,LRP1B,NKAIN3,SOX5,ADCY2,GABRB1
2.088e-07	-15.38	neurogenesis	biological process	GO:0022008	1334	16	18204	49	TNIK,NRXN1,NTM,CTNND2,BMPR1B,APOE,NTRK2,SOX5,PTPRZ1,PRKG1,NFIA,RORA,GABRB1,GPM6A,SLC1A3,PREX2
2.457e-07	-15.22	developmental process	biological process	GO:0032502	5716	33	18204	49	RANBP3L,NRXN1,ATP1A2,NTM,LSAMP,CTNND2,BMPR1B,FGFR3,SLC1A3,RORA,GABRB1,FMN2,GPM6A,CSGALNACT1,NHSL1,CADM1,SOX5,ABLIM1,MSI2,SLC1A2,COL5A3,APOE,SPARCL1,NTRK2,TNIK,PCDH9,NRG3,CPE,PREX2,CDH20,PRKG1,NFIA,PTPRZ1
2.841e-07	-15.07	neuron development	biological process	GO:0048666	859	13	18204	49	PRKG1,PTPRZ1,SLC1A3,GABRB1,GPM6A,PREX2,NRXN1,TNIK,NTM,CTNND2,BMPR1B,APOE,NTRK2
4.196e-07	-14.68	anatomical structure morphogenesis	biological process	GO:0009653	2225	20	18204	49	NRXN1,TNIK,NRG3,CPE,CTNND2,BMPR1B,APOE,NTRK2,SOX5,CDH20,ABLIM1,PRKG1,NFIA,PTPRZ1,FGFR3,SLC1A3,RORA,GPM6A,CSGALNACT1,PREX2
4.729e-07	-14.56	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-follicular_lymphoma	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-follicular_lymphoma	981	14	16828	49	ITPR2,GPC5,PCDH9,LSAMP,CTNND2,ADCY2,RORA,PRKG1,NRG3,LRP1B,HPSE2,SOX5,GABRB1,NKAIN3
9.787e-07	-13.84	cell junction	cellular component	GO:0030054	2224	19	19108	49	NFIA,GPM6A,APOE,NRG3,DTNA,TNIK,PCDH9,NTRK2,CADM1,ATP1A2,GABRB1,PTPRZ1,CTNND2,SLC1A2,CDH20,SLC1A3,FGFR3,SPARCL1,NRXN1
1.041e-06	-13.78	mantle_cell_lymphoma	COSMIC cancer mutations	mantle_cell_lymphoma	2849	23	16828	49	SLC1A2,NKAIN3,FBXL7,PRKG1,CTNND2,ADCY2,CPE,PCDH9,GPM6A,LSAMP,HPSE2,ATP13A4,GABRB1,SOX5,FMN2,CADM1,NTRK2,LRP1B,NRG3,PREX2,SLC1A3,ITPR2,GPC5
1.606e-06	-13.34	cell morphogenesis	biological process	GO:0000902	687	11	18204	49	CDH20,NRXN1,TNIK,PTPRZ1,PRKG1,CTNND2,NFIA,BMPR1B,GPM6A,SLC1A3,PREX2
2.220e-06	-13.02	oesophagus-carcinoma	COSMIC cancer mutations	oesophagus-carcinoma	4269	28	16828	49	GABRB1,SOX5,ATP13A4,HPSE2,PREX2,CADM1,LRP1B,NTRK2,NRG3,FMN2,ZBTB20,COL5A3,NFIA,ITPR2,FGFR3,FBXL7,CSGALNACT1,PRKG1,NHSL1,CDH20,ADCY2,RANBP3L,CTNND2,GPM6A,NTM,PTPRZ1,TNIK,PCDH9
2.259e-06	-13.00	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-mantle_cell_lymphoma	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-mantle_cell_lymphoma	2737	22	16828	49	ITPR2,GPC5,LSAMP,GPM6A,CPE,PCDH9,CTNND2,SLC1A3,ADCY2,FMN2,PRKG1,FBXL7,PREX2,NRG3,LRP1B,NTRK2,CADM1,SLC1A2,HPSE2,NKAIN3,SOX5,GABRB1
2.410e-06	-12.94	synapse	cellular component	GO:0045202	1473	15	19108	49	NRXN1,SLC1A3,SPARCL1,SLC1A2,PTPRZ1,CTNND2,GABRB1,ATP1A2,CADM1,NTRK2,TNIK,DTNA,NRG3,APOE,GPM6A
2.806e-06	-12.78	chronic_lymphocytic_leukaemia-small_lymphocytic_lymphoma	COSMIC cancer mutations	chronic_lymphocytic_leukaemia-small_lymphocytic_lymphoma	3511	25	16828	49	NPAS3,FBXL7,PRKG1,CTNND2,ADCY2,RANBP3L,PTPRZ1,TNIK,LSAMP,PCDH9,CPE,MSI2,MGAT4C,HPSE2,GABRB1,FMN2,BMPR1B,PREX2,NTRK2,LRP1B,DTNA,NRG3,SLC1A3,PITPNC1,GPC5
2.806e-06	-12.78	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-chronic_lymphocytic_leukaemia-small_lymphocytic_lymphoma	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-chronic_lymphocytic_leukaemia-small_lymphocytic_lymphoma	3511	25	16828	49	ADCY2,RANBP3L,CTNND2,PTPRZ1,LSAMP,TNIK,CPE,PCDH9,NPAS3,FBXL7,PRKG1,SLC1A3,PITPNC1,GPC5,GABRB1,MGAT4C,MSI2,HPSE2,PREX2,NTRK2,LRP1B,DTNA,NRG3,FMN2,BMPR1B
3.516e-06	-12.56	tibia	COSMIC cancer mutations	tibia	836	12	16828	49	PRKG1,CPE,LRP1B,LSAMP,TNIK,PREX2,GPM6A,FGFR3,CTNND2,RANBP3L,ABLIM1,NKAIN3
4.244e-06	-12.37	upper_aerodigestive_tract-larynx-carcinoma-squamous_cell_carcinoma	COSMIC cancer mutations	upper_aerodigestive_tract-larynx-carcinoma-squamous_cell_carcinoma	1946	18	16828	49	LRP1B,RBMS3,CSGALNACT1,NPAS3,BMPR1B,FMN2,RORA,SOX5,FGFR3,HPSE2,MGAT4C,PCDH9,GPM6A,TNIK,ITPR2,NRXN1,ZBTB20,COL5A3
4.307e-06	-12.36	larynx	COSMIC cancer mutations	larynx	1948	18	16828	49	SOX5,FGFR3,HPSE2,MGAT4C,LRP1B,RBMS3,NPAS3,CSGALNACT1,BMPR1B,RORA,FMN2,NRXN1,ZBTB20,COL5A3,PCDH9,GPM6A,TNIK,ITPR2
7.031e-06	-11.87	mast_cell_neoplasm	COSMIC cancer mutations	mast_cell_neoplasm	248	7	16828	49	ADCY2,HPSE2,PCDH9,NRG3,NFIA,GPC5,NPAS3
7.031e-06	-11.87	haematopoietic_and_lymphoid_tissue-haematopoietic_neoplasm-mast_cell_neoplasm	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue-haematopoietic_neoplasm-mast_cell_neoplasm	248	7	16828	49	NPAS3,GPC5,NFIA,NRG3,PCDH9,HPSE2,ADCY2
7.142e-06	-11.85	somatodendritic compartment	cellular component	GO:0036477	842	11	19108	49	APOE,GPM6A,GABRB1,CTNND2,BMPR1B,ATP1A2,CADM1,SLC1A3,NTRK2,NRXN1,ADCY2
8.905e-06	-11.63	mouth	COSMIC cancer mutations	mouth	9004	41	16828	49	SOX5,GABRB1,ATP13A4,MGAT4C,HPSE2,PREX2,NRG3,LRP1B,DTNA,NTRK2,CADM1,FMN2,RORA,SLC1A3,ZBTB20,NRXN1,COL5A3,PITPNC1,ITPR2,GPC5,CST3,SLC1A2,FGFR3,NHSL1,NPAS3,FBXL7,PRKG1,CSGALNACT1,CDH20,RANBP3L,ABLIM1,ADCY2,CTNND2,ATP1A2,LSAMP,TNIK,PTPRZ1,NTM,GPM6A,PCDH9,APOE
9.407e-06	-11.57	bone-tibia-other-chondroblastoma	COSMIC cancer mutations	bone-tibia-other-chondroblastoma	98	5	16828	49	LRP1B,LSAMP,NKAIN3,GPM6A,CTNND2
1.071e-05	-11.44	right_upper_lobe	COSMIC cancer mutations	right_upper_lobe	10376	44	16828	49	PREX2,NTRK2,LRP1B,CADM1,DTNA,NRG3,FMN2,BMPR1B,RORA,GABRB1,SOX5,MGAT4C,ATP13A4,HPSE2,NFIA,PITPNC1,ITPR2,GPC5,ZBTB20,SLC1A3,NRXN1,COL5A3,CSGALNACT1,NPAS3,FBXL7,PRKG1,NKAIN3,GLIS3,SLC1A2,FGFR3,PTPRZ1,GPM6A,NTM,LSAMP,ATP1A2,TNIK,CPE,PCDH9,APOE,CDH20,ABLIM1,ADCY2,RANBP3L,CTNND2
1.071e-05	-11.44	lung-right_upper_lobe-carcinoma-adenocarcinoma	COSMIC cancer mutations	lung-right_upper_lobe-carcinoma-adenocarcinoma	10376	44	16828	49	SLC1A2,CSGALNACT1,CDH20,RANBP3L,ADCY2,ATP1A2,GPM6A,PTPRZ1,PCDH9,CPE,ATP13A4,SOX5,BMPR1B,RORA,NRG3,COL5A3,SLC1A3,NRXN1,PITPNC1,NFIA,ITPR2,FGFR3,GLIS3,NKAIN3,FBXL7,NPAS3,PRKG1,CTNND2,ABLIM1,APOE,LSAMP,TNIK,NTM,MGAT4C,HPSE2,GABRB1,FMN2,PREX2,CADM1,NTRK2,DTNA,LRP1B,ZBTB20,GPC5
1.144e-05	-11.38	soft_tissue	COSMIC cancer mutations	soft_tissue	5828	32	16828	49	APOE,PCDH9,PTPRZ1,GPM6A,LSAMP,CTNND2,ADCY2,CDH20,FBXL7,PRKG1,NPAS3,NHSL1,FGFR3,SLC1A2,NKAIN3,GLIS3,GPC5,ITPR2,NFIA,SPARCL1,COL5A3,SLC1A3,FMN2,RORA,LRP1B,CADM1,NTRK2,NRG3,PREX2,HPSE2,GABRB1,SOX5
1.498e-05	-11.11	Salivary secretion	KEGG pathways	hsa04970	90	5	7161	26	ADCY2,ITPR2,CST3,ATP1A2,PRKG1
1.498e-05	-11.11	Salivary secretion	KEGG pathways	ko04970	90	5	7161	26	CST3,PRKG1,ATP1A2,ADCY2,ITPR2
1.598e-05	-11.04	nodular	COSMIC cancer mutations	nodular	1515	15	16828	49	CPE,ATP1A2,PTPRZ1,ABLIM1,CDH20,CTNND2,SPARCL1,LRP1B,NTRK2,PREX2,FMN2,NPAS3,GLIS3,FGFR3,ATP13A4
1.766e-05	-10.94	PDZD2 (PDZ domain containing 2)	protein interactions	23037	20	3	19454	50	CTNND2,NRXN1,CST3
1.910e-05	-10.87	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm	7307	36	16828	49	GABRB1,SOX5,HPSE2,MGAT4C,ATP13A4,CADM1,NTRK2,LRP1B,NRG3,PREX2,FMN2,BMPR1B,RORA,SLC1A3,SPARCL1,COL5A3,ITPR2,GPC5,NKAIN3,GLIS3,SLC1A2,CSGALNACT1,PRKG1,FBXL7,NHSL1,ADCY2,ABLIM1,RANBP3L,CDH20,CTNND2,PCDH9,CPE,PTPRZ1,GPM6A,LSAMP,TNIK
2.112e-05	-10.77	neuron projection	cellular component	GO:0043005	1331	13	19108	49	CTNND2,GABRB1,SLC1A2,ATP1A2,SLC1A3,GPM6A,APOE,BMPR1B,PCDH9,NTRK2,CADM1,DTNA,ADCY2
2.407e-05	-10.63	humerus	COSMIC cancer mutations	humerus	546	9	16828	49	GPM6A,LRP1B,PRKG1,GPC5,FMN2,NKAIN3,GABRB1,ADCY2,SOX5
2.421e-05	-10.63	dendrite	cellular component	GO:0030425	620	9	19108	49	NTRK2,CADM1,ADCY2,GABRB1,GPM6A,CTNND2,APOE,ATP1A2,BMPR1B
2.483e-05	-10.60	dendritic tree	cellular component	GO:0097447	622	9	19108	49	ADCY2,NTRK2,CADM1,ATP1A2,BMPR1B,GABRB1,GPM6A,CTNND2,APOE
2.586e-05	-10.56	carcinoid-endocrine_tumour	COSMIC cancer mutations	carcinoid-endocrine_tumour	7752	37	16828	49	NHSL1,PRKG1,FBXL7,CSGALNACT1,GLIS3,NKAIN3,FGFR3,SLC1A2,PCDH9,CPE,LSAMP,TNIK,ATP1A2,PTPRZ1,GPM6A,APOE,RANBP3L,ADCY2,ABLIM1,CDH20,CTNND2,NRG3,NTRK2,CADM1,LRP1B,PREX2,RORA,BMPR1B,FMN2,SOX5,GABRB1,HPSE2,ATP13A4,GPC5,ITPR2,SLC1A3,COL5A3
2.857e-05	-10.46	synapse organization	biological process	GO:0050808	333	7	18204	49	NRXN1,NRG3,CTNND2,NFIA,APOE,SPARCL1,GPM6A
2.858e-05	-10.46	mucosal	COSMIC cancer mutations	mucosal	2009	17	16828	49	PREX2,LRP1B,NRG3,BMPR1B,RORA,FMN2,GABRB1,MGAT4C,ATP13A4,FGFR3,ATP1A2,CPE,PCDH9,ABLIM1,SPARCL1,CTNND2,COL5A3
2.858e-05	-10.46	skin-mucosal-malignant_melanoma	COSMIC cancer mutations	skin-mucosal-malignant_melanoma	2009	17	16828	49	GABRB1,FGFR3,ATP13A4,MGAT4C,NRG3,LRP1B,PREX2,FMN2,RORA,BMPR1B,ABLIM1,CTNND2,COL5A3,SPARCL1,CPE,PCDH9,ATP1A2
3.402e-05	-10.29	skin-face-carcinoma-squamous_cell_carcinoma	COSMIC cancer mutations	skin-face-carcinoma-squamous_cell_carcinoma	2036	17	16828	49	RORA,FMN2,CSGALNACT1,NRG3,RBMS3,LRP1B,PREX2,FGFR3,MSI2,GABRB1,ITPR2,GPC5,PCDH9,LSAMP,PTPRZ1,GPM6A,ABLIM1
4.105e-05	-10.10	oesophagus-carcinoma-squamous_cell_carcinoma	COSMIC cancer mutations	oesophagus-carcinoma-squamous_cell_carcinoma	6486	33	16828	49	ITPR2,GPC5,PITPNC1,COL5A3,SPARCL1,NRXN1,ZBTB20,BMPR1B,FMN2,NRG3,CADM1,LRP1B,PREX2,HPSE2,ATP13A4,MGAT4C,SOX5,PCDH9,CPE,TNIK,ATP1A2,GPM6A,PTPRZ1,CTNND2,RANBP3L,ADCY2,ABLIM1,FBXL7,CSGALNACT1,NPAS3,PRKG1,FGFR3,GLIS3
4.197e-05	-10.08	neuron projection morphogenesis	biological process	GO:0048812	486	8	18204	49	NRXN1,TNIK,PTPRZ1,CTNND2,PRKG1,BMPR1B,GPM6A,PREX2
4.512e-05	-10.01	plasma membrane bounded cell projection morphogenesis	biological process	GO:0120039	491	8	18204	49	GPM6A,PREX2,TNIK,NRXN1,PTPRZ1,CTNND2,PRKG1,BMPR1B
4.606e-05	-9.99	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-plasma_cell_myeloma	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-plasma_cell_myeloma	1263	13	16828	49	ATP13A4,FGFR3,HPSE2,LRP1B,NTRK2,NRG3,FMN2,ABLIM1,ADCY2,CTNND2,GPM6A,NTM,TNIK
4.606e-05	-9.99	plasma_cell_myeloma	COSMIC cancer mutations	plasma_cell_myeloma	1263	13	16828	49	ATP13A4,HPSE2,FGFR3,FMN2,NRG3,LRP1B,NTRK2,CTNND2,ADCY2,ABLIM1,TNIK,NTM,GPM6A
4.847e-05	-9.93	cell projection morphogenesis	biological process	GO:0048858	496	8	18204	49	BMPR1B,CTNND2,PRKG1,PTPRZ1,TNIK,NRXN1,PREX2,GPM6A
4.917e-05	-9.92	Astrocytic Glutamate-Glutamine Uptake And Metabolism	REACTOME pathways	R-HSA-210455	4	2	10285	30	SLC1A3,SLC1A2
4.917e-05	-9.92	Neurotransmitter uptake and Metabolism In Glial Cells	REACTOME pathways	R-HSA-112313	4	2	10285	30	SLC1A3,SLC1A2
5.094e-05	-9.88	astrocytoma_Grade_I	COSMIC cancer mutations	astrocytoma_Grade_I	139	5	16828	49	PRKG1,GPC5,FGFR3,LRP1B,NRG3
5.275e-05	-9.85	central nervous system development	biological process	GO:0007417	995	11	18204	49	NTRK2,RORA,GABRB1,PTPRZ1,PRKG1,BMPR1B,SLC1A2,MSI2,ATP1A2,NRG3,PCDH9
5.396e-05	-9.83	scalp	COSMIC cancer mutations	scalp	2110	17	16828	49	RORA,FMN2,PRKG1,RBMS3,CADM1,PREX2,FGFR3,ATP13A4,SOX5,GPC5,NFIA,ATP1A2,LSAMP,NTM,PTPRZ1,COL5A3,NRXN1
5.476e-05	-9.81	pancreas-carcinoid-endocrine_tumour	COSMIC cancer mutations	pancreas-carcinoid-endocrine_tumour	7250	35	16828	49	ITPR2,GPC5,COL5A3,SLC1A3,BMPR1B,RORA,FMN2,NTRK2,CADM1,LRP1B,NRG3,PREX2,HPSE2,ATP13A4,GABRB1,SOX5,APOE,CPE,PCDH9,GPM6A,ATP1A2,LSAMP,CTNND2,ABLIM1,ADCY2,RANBP3L,CDH20,CSGALNACT1,FBXL7,PRKG1,NHSL1,FGFR3,SLC1A2,NKAIN3,GLIS3
5.783e-05	-9.76	skin-trunk-malignant_melanoma-nodular	COSMIC cancer mutations	skin-trunk-malignant_melanoma-nodular	1291	13	16828	49	GLIS3,ATP13A4,LRP1B,NTRK2,PREX2,NPAS3,ABLIM1,CDH20,CTNND2,SPARCL1,CPE,ATP1A2,PTPRZ1
6.426e-05	-9.65	face	COSMIC cancer mutations	face	2139	17	16828	49	FGFR3,MSI2,GABRB1,CSGALNACT1,RORA,FMN2,LRP1B,RBMS3,NRG3,PREX2,ABLIM1,ITPR2,GPC5,PCDH9,PTPRZ1,GPM6A,LSAMP
6.504e-05	-9.64	upper_aerodigestive_tract-mouth-carcinoma-squamous_cell_carcinoma	COSMIC cancer mutations	upper_aerodigestive_tract-mouth-carcinoma-squamous_cell_carcinoma	6953	34	16828	49	CST3,FGFR3,SLC1A2,NHSL1,PRKG1,CSGALNACT1,FBXL7,RANBP3L,ADCY2,ABLIM1,CDH20,CTNND2,PCDH9,LSAMP,ATP1A2,TNIK,NTM,PTPRZ1,GPM6A,SOX5,MGAT4C,ATP13A4,NRG3,DTNA,CADM1,LRP1B,PREX2,FMN2,RORA,NRXN1,ZBTB20,ITPR2,GPC5,PITPNC1
6.856e-05	-9.59	high-affinity L-glutamate transmembrane transporter activity	molecular function	GO:0005314	5	2	18094	48	SLC1A2,SLC1A3
6.856e-05	-9.59	glutamate:sodium symporter activity	molecular function	GO:0015501	5	2	18094	48	SLC1A3,SLC1A2
7.004e-05	-9.57	cell differentiation	biological process	GO:0030154	3645	22	18204	49	MSI2,SOX5,GPM6A,RORA,FMN2,GABRB1,SLC1A3,FGFR3,CADM1,NHSL1,NTM,NRXN1,BMPR1B,CTNND2,RANBP3L,PTPRZ1,NFIA,PRKG1,PREX2,TNIK,APOE,NTRK2
7.061e-05	-9.56	D-aspartate transmembrane transport	biological process	GO:0070777	5	2	18204	49	SLC1A3,SLC1A2
7.061e-05	-9.56	D-aspartate import across plasma membrane	biological process	GO:0070779	5	2	18204	49	SLC1A2,SLC1A3
7.070e-05	-9.56	neurotransmitter uptake	biological process	GO:0001504	30	3	18204	49	SLC1A2,SLC1A3,ATP1A2
7.095e-05	-9.55	cellular developmental process	biological process	GO:0048869	3648	22	18204	49	APOE,NTRK2,TNIK,PREX2,PRKG1,NFIA,PTPRZ1,RANBP3L,NRXN1,NTM,CTNND2,BMPR1B,FGFR3,SLC1A3,FMN2,RORA,GABRB1,GPM6A,NHSL1,CADM1,SOX5,MSI2
7.700e-05	-9.47	cell body	cellular component	GO:0044297	556	8	19108	49	ATP1A2,BMPR1B,CTNND2,NRXN1,GPM6A,SLC1A3,SLC1A2,APOE
7.923e-05	-9.44	cell junction organization	biological process	GO:0034330	532	8	18204	49	CTNND2,NFIA,NRXN1,NRG3,CDH20,APOE,GPM6A,SPARCL1
8.255e-05	-9.40	NTM (neurotrimin)	protein interactions	50863	33	3	19454	50	GPM6A,NTM,LSAMP
8.349e-05	-9.39	multicellular organismal process	biological process	GO:0032501	6177	30	18204	49	CTNND2,BMPR1B,LSAMP,NRXN1,NTM,ATP1A2,RANBP3L,SLC1A2,ABLIM1,MSI2,SOX5,CADM1,RORA,GABRB1,CSGALNACT1,GPM6A,FGFR3,SLC1A3,CPE,TNIK,PCDH9,NRG3,NTRK2,APOE,DTNA,PTPRZ1,PRKG1,NFIA,CDH20,PREX2
8.356e-05	-9.39	neuron projection development	biological process	GO:0031175	693	9	18204	49	PREX2,GPM6A,APOE,PTPRZ1,BMPR1B,CTNND2,PRKG1,NRXN1,TNIK
9.447e-05	-9.27	response to auditory stimulus	biological process	GO:0010996	33	3	18204	49	ATP1A2,SLC1A3,NRXN1
9.946e-05	-9.22	cartilage development	biological process	GO:0051216	173	5	18204	49	CSGALNACT1,FGFR3,SOX5,BMPR1B,NFIA
1.011e-04	-9.20	PRNP (prion protein (Kanno blood group))	protein interactions	5621	1118	11	19454	50	APOE,NHSL1,ABLIM1,ATP1A2,PTPRZ1,MSI2,CPE,GPM6A,SLC1A3,SPARCL1,LSAMP
1.023e-04	-9.19	bone	COSMIC cancer mutations	bone	8157	37	16828	49	FMN2,RORA,PREX2,NTRK2,LRP1B,CADM1,DTNA,NRG3,ATP13A4,HPSE2,GABRB1,SOX5,ITPR2,GPC5,SPARCL1,COL5A3,ZBTB20,SLC1A3,NRXN1,CSGALNACT1,PRKG1,NPAS3,FGFR3,NKAIN3,GLIS3,CST3,GPM6A,PTPRZ1,TNIK,ATP1A2,LSAMP,PCDH9,CPE,CTNND2,ABLIM1,ADCY2,RANBP3L
1.046e-04	-9.17	pharynx	COSMIC cancer mutations	pharynx	2696	19	16828	49	FGFR3,SLC1A2,ATP13A4,GABRB1,NPAS3,NHSL1,FMN2,NTRK2,DTNA,LRP1B,NRG3,PREX2,CTNND2,GPC5,NFIA,PITPNC1,PCDH9,PTPRZ1,ATP1A2
1.057e-04	-9.15	D-amino acid transport	biological process	GO:0042940	6	2	18204	49	SLC1A3,SLC1A2
1.057e-04	-9.15	L-aspartate import across plasma membrane	biological process	GO:0140009	6	2	18204	49	SLC1A3,SLC1A2
1.176e-04	-9.05	proteoglycan binding	molecular function	GO:0043394	36	3	18094	48	HPSE2,COL5A3,APOE
1.249e-04	-8.99	MAPT (microtubule associated protein tau)	protein interactions	4137	948	10	19454	50	SLC1A3,LSAMP,CTNND2,GPM6A,ABLIM1,NTM,SLC1A2,TNIK,APOE,ATP1A2
1.445e-04	-8.84	trans-synaptic signaling	biological process	GO:0099537	431	7	18204	49	NRXN1,SLC1A2,SLC1A3,DTNA,GABRB1,APOE,NTRK2
1.487e-04	-8.81	Na-dicarboxylate_symporter	interpro domains	IPR001991	7	2	18521	50	SLC1A3,SLC1A2
1.487e-04	-8.81	Na-dicarboxylate_symporter_CS	interpro domains	IPR018107	7	2	18521	50	SLC1A3,SLC1A2
1.487e-04	-8.81	Na:dicarbo_symporter_sf	interpro domains	IPR036458	7	2	18521	50	SLC1A3,SLC1A2
1.546e-04	-8.77	SDF	pfam domains	PF00375	7	2	17795	49	SLC1A3,SLC1A2
1.578e-04	-8.75	cell development	biological process	GO:0048468	2236	16	18204	49	PTPRZ1,PRKG1,MSI2,PREX2,GPM6A,GABRB1,FMN2,RORA,SLC1A3,BMPR1B,CTNND2,NTM,TNIK,NRXN1,NTRK2,APOE
1.603e-04	-8.74	trunk	COSMIC cancer mutations	trunk	3554	22	16828	49	GLIS3,FGFR3,NPAS3,CDH20,ABLIM1,CTNND2,PTPRZ1,ATP1A2,LSAMP,PCDH9,CPE,SOX5,ATP13A4,MGAT4C,HPSE2,PREX2,NTRK2,LRP1B,NRG3,SLC1A3,NRXN1,SPARCL1
1.712e-04	-8.67	cell morphogenesis involved in neuron differentiation	biological process	GO:0048667	443	7	18204	49	SLC1A3,PREX2,NRXN1,PRKG1,CTNND2,BMPR1B,PTPRZ1
1.794e-04	-8.63	Sodium:dicarboxylate symporter	gene3d domains	1.10.3860.10	7	2	14470	43	SLC1A2,SLC1A3
1.869e-04	-8.58	lymphoid_neoplasm	COSMIC cancer mutations	lymphoid_neoplasm	12233	46	16828	49	RORA,BMPR1B,NRG3,ATP13A4,SOX5,ITPR2,PITPNC1,NFIA,COL5A3,SPARCL1,NRXN1,SLC1A3,CSGALNACT1,SLC1A2,PCDH9,CPE,ATP1A2,PTPRZ1,GPM6A,RANBP3L,ADCY2,CDH20,FMN2,DTNA,LRP1B,CADM1,NTRK2,PREX2,HPSE2,MSI2,MGAT4C,GABRB1,GPC5,ZBTB20,NHSL1,FBXL7,NPAS3,PRKG1,FGFR3,GLIS3,NKAIN3,LSAMP,TNIK,NTM,CTNND2,ABLIM1
2.035e-04	-8.50	cell projection	cellular component	GO:0042995	2398	16	19108	49	ATP1A2,SLC1A2,GABRB1,CTNND2,SLC1A3,NRXN1,BMPR1B,APOE,FMN2,GPM6A,DTNA,ADCY2,CADM1,PCDH9,NTRK2,ABLIM1
2.128e-04	-8.46	synaptic signaling	biological process	GO:0099536	459	7	18204	49	DTNA,SLC1A3,GABRB1,APOE,NTRK2,NRXN1,SLC1A2
2.247e-04	-8.40	behavior	biological process	GO:0007610	619	8	18204	49	APOE,SLC1A3,PREX2,NTRK2,ATP1A2,NRXN1,PTPRZ1,SLC1A2
2.273e-04	-8.39	cellular response to organic cyclic compound	biological process	GO:0071407	464	7	18204	49	SLC1A2,ITPR2,ATP1A2,ADCY2,SLC1A3,RORA,GABRB1
2.300e-04	-8.38	cervix-carcinoma-squamous_cell_carcinoma	COSMIC cancer mutations	cervix-carcinoma-squamous_cell_carcinoma	11789	45	16828	49	ATP1A2,PTPRZ1,GPM6A,CPE,PCDH9,CDH20,RANBP3L,ADCY2,CSGALNACT1,SLC1A2,PITPNC1,NFIA,ITPR2,SLC1A3,NRXN1,COL5A3,SPARCL1,NRG3,BMPR1B,RORA,SOX5,ATP13A4,TNIK,LSAMP,NTM,ABLIM1,CTNND2,NHSL1,PRKG1,FBXL7,NPAS3,GLIS3,CST3,FGFR3,GPC5,ZBTB20,PREX2,DTNA,CADM1,LRP1B,NTRK2,FMN2,GABRB1,MGAT4C,HPSE2
2.304e-04	-8.38	NEGR1 (neuronal growth regulator 1)	protein interactions	257194	9	2	19454	50	LSAMP,NTM
2.304e-04	-8.38	LSAMP (limbic system associated membrane protein)	protein interactions	4045	9	2	19454	50	NTM,LSAMP
2.328e-04	-8.37	cervix	COSMIC cancer mutations	cervix	11793	45	16828	49	NFIA,PITPNC1,ITPR2,SPARCL1,COL5A3,SLC1A3,NRXN1,RORA,BMPR1B,NRG3,ATP13A4,SOX5,PTPRZ1,GPM6A,ATP1A2,PCDH9,CPE,CDH20,ADCY2,RANBP3L,CSGALNACT1,SLC1A2,GPC5,ZBTB20,FMN2,PREX2,NTRK2,DTNA,LRP1B,CADM1,MGAT4C,HPSE2,GABRB1,NTM,LSAMP,TNIK,CTNND2,ABLIM1,NPAS3,FBXL7,PRKG1,NHSL1,FGFR3,GLIS3,CST3
2.333e-04	-8.36	neuronal cell body	cellular component	GO:0043025	489	7	19108	49	NRXN1,SLC1A3,APOE,CTNND2,GPM6A,BMPR1B,ATP1A2
2.402e-04	-8.33	acidic amino acid transport	biological process	GO:0015800	45	3	18204	49	SLC1A2,NTRK2,SLC1A3
2.443e-04	-8.32	central_nervous_system-cerebellum-glioma-astrocytoma_Grade_I	COSMIC cancer mutations	central_nervous_system-cerebellum-glioma-astrocytoma_Grade_I	105	4	16828	49	LRP1B,NRG3,GPC5,PRKG1
2.561e-04	-8.27	animal organ development	biological process	GO:0048513	2846	18	18204	49	FGFR3,RORA,CSGALNACT1,GPM6A,CADM1,SOX5,ABLIM1,PRKG1,SLC1A2,NFIA,RANBP3L,COL5A3,NTRK2,PCDH9,ATP1A2,NRG3,CPE,BMPR1B
2.645e-04	-8.24	NA_DICARBOXYL_SYMP_1	prosite domains	PS00713	7	2	12186	44	SLC1A2,SLC1A3
2.645e-04	-8.24	NA_DICARBOXYL_SYMP_2	prosite domains	PS00714	7	2	12186	44	SLC1A2,SLC1A3
2.680e-04	-8.22	haematopoietic_and_lymphoid_tissue-lymph_node-lymphoid_neoplasm-diffuse_large_B_cell_lymphoma	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue-lymph_node-lymphoid_neoplasm-diffuse_large_B_cell_lymphoma	748	9	16828	49	NTRK2,DTNA,LRP1B,PRKG1,ITPR2,SOX5,RANBP3L,SLC1A3,CTNND2
2.790e-04	-8.18	superficial_spreading	COSMIC cancer mutations	superficial_spreading	1110	11	16828	49	PRKG1,LRP1B,PREX2,FGFR3,ATP13A4,MGAT4C,GABRB1,NTM,COL5A3,CTNND2,ADCY2
2.888e-04	-8.15	EDTRNSPORT	prints domains	PR00173	7	2	5227	20	SLC1A2,SLC1A3
2.946e-04	-8.13	central_nervous_system-brain-primitive_neuroectodermal_tumour-medulloblastoma-large_cell	COSMIC cancer mutations	central_nervous_system-brain-primitive_neuroectodermal_tumour-medulloblastoma-large_cell	1117	11	16828	49	GPC5,PRKG1,FMN2,LRP1B,NRG3,ATP13A4,SLC1A2,GABRB1,ADCY2,SOX5,CDH20
3.017e-04	-8.11	cell-cell signaling	biological process	GO:0007267	822	9	18204	49	NRXN1,CPE,SLC1A2,FGFR3,DTNA,SLC1A3,GABRB1,APOE,NTRK2
3.150e-04	-8.06	cellular response to cocaine	biological process	GO:0071314	10	2	18204	49	SLC1A2,SLC1A3
3.150e-04	-8.06	neuronal action potential propagation	biological process	GO:0019227	10	2	18204	49	NTRK2,ATP1A2
3.150e-04	-8.06	action potential propagation	biological process	GO:0098870	10	2	18204	49	ATP1A2,NTRK2
3.508e-04	-7.96	IRAG1 (inositol 1,4,5-triphosphate receptor associated 1)	protein interactions	10335	11	2	19454	50	ITPR2,PRKG1
3.521e-04	-7.95	skin-leg-malignant_melanoma-superficial_spreading	COSMIC cancer mutations	skin-leg-malignant_melanoma-superficial_spreading	210	5	16828	49	PRKG1,ATP13A4,COL5A3,LRP1B,NTM
3.844e-04	-7.86	L-aspartate transmembrane transport	biological process	GO:0070778	11	2	18204	49	SLC1A2,SLC1A3
3.844e-04	-7.86	L-glutamate import across plasma membrane	biological process	GO:0098712	11	2	18204	49	SLC1A2,SLC1A3
3.889e-04	-7.85	connective tissue development	biological process	GO:0061448	232	5	18204	49	CSGALNACT1,FGFR3,SOX5,BMPR1B,NFIA
4.018e-04	-7.82	ear	COSMIC cancer mutations	ear	624	8	16828	49	FGFR3,SPARCL1,MGAT4C,GABRB1,ZBTB20,NPAS3,PRKG1,LRP1B
4.026e-04	-7.82	leg	COSMIC cancer mutations	leg	969	10	16828	49	ZBTB20,FGFR3,ATP13A4,COL5A3,LRP1B,NRG3,NTM,PTPRZ1,PRKG1,FMN2
4.129e-04	-7.79	plasma membrane bounded cell projection	cellular component	GO:0120025	2285	15	19108	49	BMPR1B,FMN2,APOE,GPM6A,DTNA,ADCY2,CADM1,NTRK2,ABLIM1,PCDH9,ATP1A2,SLC1A2,CTNND2,GABRB1,SLC1A3
4.203e-04	-7.77	PROK2 (prokineticin 2)	protein interactions	60675	12	2	19454	50	CPE,LRP1B
4.404e-04	-7.73	Ig_I-set	interpro domains	IPR013098	132	4	18521	50	LSAMP,FGFR3,NTRK2,NTM
4.529e-04	-7.70	Ig_sub2	interpro domains	IPR003598	239	5	18521	50	CADM1,LSAMP,NTRK2,NTM,FGFR3
4.593e-04	-7.69	haematopoietic_neoplasm	COSMIC cancer mutations	haematopoietic_neoplasm	11082	43	16828	49	SLC1A2,FGFR3,GLIS3,NKAIN3,NHSL1,PRKG1,FBXL7,NPAS3,CSGALNACT1,RBMS3,CTNND2,CDH20,RANBP3L,ADCY2,ABLIM1,ATP1A2,TNIK,LSAMP,PTPRZ1,NTM,PCDH9,CPE,ATP13A4,MSI2,HPSE2,SOX5,GABRB1,FMN2,RORA,BMPR1B,PREX2,NRG3,LRP1B,CADM1,DTNA,NTRK2,COL5A3,SPARCL1,SLC1A3,NRXN1,NFIA,GPC5,ITPR2
4.605e-04	-7.68	auditory behavior	biological process	GO:0031223	12	2	18204	49	NRXN1,SLC1A3
4.733e-04	-7.66	I-set	pfam domains	PF07679	132	4	17795	49	FGFR3,NTRK2,LSAMP,NTM
4.832e-04	-7.64	skin-scalp-carcinoma-squamous_cell_carcinoma	COSMIC cancer mutations	skin-scalp-carcinoma-squamous_cell_carcinoma	1596	13	16828	49	COL5A3,NRXN1,GPC5,PTPRZ1,ATP1A2,LSAMP,ATP13A4,FGFR3,SOX5,PRKG1,RORA,CADM1,RBMS3
4.928e-04	-7.62	NAKATPASE	prints domains	PR00121	9	2	5227	20	ATP13A4,ATP1A2
5.359e-04	-7.53	endochondral bone morphogenesis	biological process	GO:0060350	59	3	18204	49	BMPR1B,CSGALNACT1,FGFR3
5.428e-04	-7.52	neurotransmitter transport	biological process	GO:0006836	140	4	18204	49	SLC1A3,ATP1A2,NRXN1,SLC1A2
5.954e-04	-7.43	receptor complex	cellular component	GO:0043235	409	6	19108	49	FGFR3,GABRB1,NTRK2,LRP1B,BMPR1B,ITPR2
6.069e-04	-7.41	Ig_3	pfam domains	PF13927	141	4	17795	49	CADM1,LSAMP,NTM,FGFR3
6.131e-04	-7.40	skin-ear-carcinoma-squamous_cell_carcinoma	COSMIC cancer mutations	skin-ear-carcinoma-squamous_cell_carcinoma	506	7	16828	49	PRKG1,NPAS3,ZBTB20,GABRB1,MGAT4C,SPARCL1,FGFR3
6.145e-04	-7.39	L-glutamate transmembrane transporter activity	molecular function	GO:0005313	14	2	18094	48	SLC1A2,SLC1A3
6.187e-04	-7.39	glutamatergic synapse	cellular component	GO:0098978	412	6	19108	49	NRG3,TNIK,SPARCL1,GPM6A,APOE,SLC1A2
6.327e-04	-7.37	mechanosensory behavior	biological process	GO:0007638	14	2	18204	49	SLC1A3,NRXN1
6.356e-04	-7.36	adult behavior	biological process	GO:0030534	146	4	18204	49	ATP1A2,NRXN1,PREX2,SLC1A2
6.366e-04	-7.36	Neurexin-like	interpro domains	IPR003585	14	2	18521	50	CADM1,NRXN1
6.542e-04	-7.33	upper_aerodigestive_tract	COSMIC cancer mutations	upper_aerodigestive_tract	13181	47	16828	49	COL5A3,NRXN1,SLC1A3,ITPR2,PITPNC1,NFIA,ATP13A4,SOX5,BMPR1B,RORA,NRG3,RANBP3L,ADCY2,CDH20,PCDH9,ATP1A2,PTPRZ1,GPM6A,SLC1A2,CSGALNACT1,ZBTB20,GPC5,HPSE2,MSI2,MGAT4C,GABRB1,FMN2,CADM1,NTRK2,LRP1B,DTNA,PREX2,CTNND2,ABLIM1,APOE,LSAMP,TNIK,NTM,FGFR3,CST3,GLIS3,NKAIN3,NHSL1,PRKG1,FBXL7,NPAS3,RBMS3
6.750e-04	-7.30	extremity	COSMIC cancer mutations	extremity	1876	14	16828	49	ATP13A4,HPSE2,FGFR3,PREX2,LRP1B,NTRK2,FMN2,FBXL7,CDH20,ADCY2,COL5A3,PTPRZ1,PCDH9,PITPNC1
6.949e-04	-7.27	Glutamatergic synapse	KEGG pathways	hsa04724	114	4	7161	26	ITPR2,ADCY2,SLC1A3,SLC1A2
6.949e-04	-7.27	Glutamatergic synapse	KEGG pathways	ko04724	114	4	7161	26	SLC1A3,SLC1A2,ITPR2,ADCY2
7.411e-04	-7.21	urinary_tract-bladder-carcinoma-transitional_cell_carcinoma	COSMIC cancer mutations	urinary_tract-bladder-carcinoma-transitional_cell_carcinoma	6040	29	16828	49	COL5A3,SPARCL1,NRXN1,SLC1A3,ZBTB20,ITPR2,GPC5,NFIA,HPSE2,ATP13A4,MGAT4C,GABRB1,FMN2,NRG3,DTNA,NTRK2,CADM1,LRP1B,PREX2,ABLIM1,ADCY2,CDH20,PCDH9,ATP1A2,GPM6A,PTPRZ1,FGFR3,GLIS3,PRKG1
7.457e-04	-7.20	transitional_cell_carcinoma	COSMIC cancer mutations	transitional_cell_carcinoma	6042	29	16828	49	CDH20,ADCY2,ABLIM1,ATP1A2,GPM6A,PTPRZ1,PCDH9,FGFR3,GLIS3,PRKG1,COL5A3,SPARCL1,SLC1A3,ZBTB20,NRXN1,NFIA,ITPR2,GPC5,ATP13A4,MGAT4C,HPSE2,GABRB1,FMN2,PREX2,NRG3,CADM1,LRP1B,DTNA,NTRK2
7.526e-04	-7.19	cellular response to endogenous stimulus	biological process	GO:0071495	1135	10	18204	49	NFIA,SLC1A2,BMPR1B,ITPR2,SOX5,ATP1A2,NTRK2,FGFR3,SLC1A3,GABRB1
7.564e-04	-7.19	forebrain development	biological process	GO:0030900	408	6	18204	49	SLC1A2,PRKG1,PCDH9,NRG3,ATP1A2,NTRK2
7.686e-04	-7.17	adenoma	COSMIC cancer mutations	adenoma	2873	18	16828	49	CDH20,ZBTB20,ADCY2,COL5A3,CTNND2,GPM6A,PTPRZ1,PCDH9,APOE,GPC5,SOX5,HPSE2,FGFR3,LRP1B,NTRK2,BMPR1B,NPAS3,PRKG1
8.086e-04	-7.12	human chr3q13.31	chromosome location	human chr3q13.31	22	2	26134	50	ZBTB20,LSAMP
8.111e-04	-7.12	cell adhesion	biological process	GO:0007155	942	9	18204	49	SPARCL1,COL5A3,CADM1,LSAMP,CDH20,PCDH9,NTM,NRXN1,CTNND2
8.133e-04	-7.11	vascular process in circulatory system	biological process	GO:0003018	273	5	18204	49	APOE,ATP1A2,SLC1A3,PRKG1,SLC1A2
8.145e-04	-7.11	retina development in camera-type eye	biological process	GO:0060041	156	4	18204	49	GPM6A,NTRK2,BMPR1B,NFIA
8.264e-04	-7.10	chemical synaptic transmission	biological process	GO:0007268	415	6	18204	49	SLC1A2,NRXN1,GABRB1,APOE,DTNA,SLC1A3
8.264e-04	-7.10	anterograde trans-synaptic signaling	biological process	GO:0098916	415	6	18204	49	APOE,GABRB1,DTNA,SLC1A3,NRXN1,SLC1A2
8.315e-04	-7.09	locomotory exploration behavior	biological process	GO:0035641	16	2	18204	49	ATP1A2,APOE
8.358e-04	-7.09	NS-malignant_melanoma	COSMIC cancer mutations	NS-malignant_melanoma	3420	20	16828	49	GABRB1,GLIS3,FGFR3,ATP13A4,MGAT4C,NRG3,CADM1,LRP1B,PREX2,FMN2,NRXN1,ADCY2,CTNND2,COL5A3,PCDH9,ATP1A2,PTPRZ1,ITPR2,GPC5,PITPNC1
8.443e-04	-7.08	plasma membrane bounded cell projection organization	biological process	GO:0120036	1152	10	18204	49	ABLIM1,TNIK,NRXN1,PTPRZ1,PRKG1,CTNND2,BMPR1B,APOE,GPM6A,PREX2
8.541e-04	-7.07	learning or memory	biological process	GO:0007611	276	5	18204	49	PTPRZ1,NTRK2,NRXN1,ATP1A2,APOE
8.975e-04	-7.02	presynaptic membrane	cellular component	GO:0042734	168	4	19108	49	SLC1A2,GABRB1,GPM6A,NRXN1
1.022e-03	-6.89	Htt (huntingtin)	protein interactions	15194	77	3	19454	50	GPM6A,NTM,LSAMP
1.026e-03	-6.88	acidic amino acid transmembrane transporter activity	molecular function	GO:0015172	18	2	18094	48	SLC1A2,SLC1A3
1.026e-03	-6.88	heparan sulfate proteoglycan binding	molecular function	GO:0043395	18	2	18094	48	HPSE2,APOE
1.056e-03	-6.85	positive regulation of circadian rhythm	biological process	GO:0042753	18	2	18204	49	RORA,PRKG1
1.056e-03	-6.85	negative regulation of platelet activation	biological process	GO:0010544	18	2	18204	49	PRKG1,APOE
1.063e-03	-6.85	ATPase_P-typ_cation-transptr_N	interpro domains	IPR004014	18	2	18521	50	ATP13A4,ATP1A2
1.105e-03	-6.81	Cation_ATPase_N	pfam domains	PF00690	18	2	17795	49	ATP13A4,ATP1A2
1.154e-03	-6.76	cell projection organization	biological process	GO:0030030	1200	10	18204	49	PREX2,APOE,GPM6A,PTPRZ1,CTNND2,PRKG1,BMPR1B,ABLIM1,NRXN1,TNIK
1.179e-03	-6.74	cartilage condensation	biological process	GO:0001502	19	2	18204	49	BMPR1B,SOX5
1.179e-03	-6.74	negative regulation of alcohol biosynthetic process	biological process	GO:1902931	19	2	18204	49	APOE,PRKG1
1.210e-03	-6.72	dicarboxylic acid transport	biological process	GO:0006835	78	3	18204	49	SLC1A3,SLC1A2,NTRK2
1.221e-03	-6.71	postsynapse	cellular component	GO:0098794	646	7	19108	49	CADM1,TNIK,NTRK2,GPM6A,GABRB1,CTNND2,ATP1A2
1.247e-03	-6.69	4.1m	smart domains	SM00294	14	2	9717	37	NRXN1,CADM1
1.274e-03	-6.67	central nervous system neuron differentiation	biological process	GO:0021953	176	4	18204	49	NTRK2,BMPR1B,GABRB1,RORA
1.293e-03	-6.65	transmembrane receptor protein kinase activity	molecular function	GO:0019199	81	3	18094	48	BMPR1B,NTRK2,FGFR3
1.303e-03	-6.64	intestinal_adenocarcinoma	COSMIC cancer mutations	intestinal_adenocarcinoma	7225	32	16828	49	NFIA,PITPNC1,ITPR2,COL5A3,ZBTB20,NRXN1,RORA,FMN2,PREX2,NTRK2,LRP1B,NRG3,ATP13A4,HPSE2,SOX5,NTM,PTPRZ1,ATP1A2,LSAMP,PCDH9,CTNND2,CDH20,ADCY2,RANBP3L,PRKG1,CSGALNACT1,FBXL7,NPAS3,NHSL1,SLC1A2,FGFR3,CST3
1.303e-03	-6.64	stomach-carcinoma-intestinal_adenocarcinoma	COSMIC cancer mutations	stomach-carcinoma-intestinal_adenocarcinoma	7225	32	16828	49	NRXN1,ZBTB20,COL5A3,ITPR2,NFIA,PITPNC1,SOX5,HPSE2,ATP13A4,NTRK2,LRP1B,NRG3,PREX2,RORA,FMN2,ADCY2,RANBP3L,CDH20,CTNND2,PCDH9,NTM,PTPRZ1,ATP1A2,LSAMP,CST3,FGFR3,SLC1A2,FBXL7,NPAS3,PRKG1,CSGALNACT1,NHSL1
1.307e-03	-6.64	aspartate transmembrane transport	biological process	GO:0015810	20	2	18204	49	SLC1A3,SLC1A2
1.307e-03	-6.64	positive regulation of chondrocyte differentiation	biological process	GO:0032332	20	2	18204	49	BMPR1B,SOX5
1.439e-03	-6.54	thyroid-carcinoma	COSMIC cancer mutations	thyroid-carcinoma	4126	22	16828	49	CADM1,DTNA,LRP1B,PRKG1,SOX5,GLIS3,FGFR3,ATP13A4,PCDH9,CPE,LSAMP,ATP1A2,TNIK,PTPRZ1,GPC5,ITPR2,NFIA,NRXN1,ADCY2,CTNND2,COL5A3,SPARCL1
1.443e-03	-6.54	cell aggregation	biological process	GO:0098743	21	2	18204	49	BMPR1B,SOX5
1.459e-03	-6.53	uveal_tract	COSMIC cancer mutations	uveal_tract	587	7	16828	49	CPE,PCDH9,PREX2,ADCY2,RANBP3L,FGFR3,CTNND2
1.550e-03	-6.47	chondrocyte differentiation	biological process	GO:0002062	85	3	18204	49	BMPR1B,FGFR3,SOX5
1.582e-03	-6.45	TIMM10B (translocase of inner mitochondrial membrane 10B)	protein interactions	26515	23	2	19454	50	HPSE2,MSI2
1.584e-03	-6.45	negative regulation of muscle contraction	biological process	GO:0045932	22	2	18204	49	PRKG1,ATP1A2
1.584e-03	-6.45	intracellular sodium ion homeostasis	biological process	GO:0006883	22	2	18204	49	SLC1A3,ATP1A2
1.594e-03	-6.44	DEP_dom	interpro domains	IPR000591	22	2	18521	50	FMN2,PREX2
1.603e-03	-6.44	transport across blood-brain barrier	biological process	GO:0150104	86	3	18204	49	SLC1A3,ATP1A2,SLC1A2
1.603e-03	-6.44	vascular transport	biological process	GO:0010232	86	3	18204	49	SLC1A3,ATP1A2,SLC1A2
1.604e-03	-6.44	CTDSPL (CTD small phosphatase like)	protein interactions	10217	90	3	19454	50	DTNA,FMN2,CADM1
1.624e-03	-6.42	cognition	biological process	GO:0050890	319	5	18204	49	PTPRZ1,NTRK2,APOE,ATP1A2,NRXN1
1.631e-03	-6.42	intracellular signaling cassette	biological process	GO:0141124	837	8	18204	49	PREX2,ADCY2,FGFR3,APOE,PRKG1,ITPR2,ATP1A2,TNIK
1.637e-03	-6.41	Cation_ATPase_N	smart domains	SM00831	16	2	9717	37	ATP13A4,ATP1A2
1.669e-03	-6.40	HS-GAG degradation	REACTOME pathways	R-HSA-2024096	21	2	10285	30	HPSE2,GPC5
1.683e-03	-6.39	amino acid:sodium symporter activity	molecular function	GO:0005283	23	2	18094	48	SLC1A2,SLC1A3
1.687e-03	-6.38	bronchioloalveolar_adenocarcinoma	COSMIC cancer mutations	bronchioloalveolar_adenocarcinoma	778	8	16828	49	TNIK,NTRK2,PRKG1,BMPR1B,ADCY2,SOX5,CTNND2,FGFR3
1.687e-03	-6.38	lung-carcinoma-bronchioloalveolar_adenocarcinoma	COSMIC cancer mutations	lung-carcinoma-bronchioloalveolar_adenocarcinoma	778	8	16828	49	ADCY2,SOX5,CTNND2,FGFR3,TNIK,NTRK2,PRKG1,BMPR1B
1.702e-03	-6.38	abdomen	COSMIC cancer mutations	abdomen	603	7	16828	49	RANBP3L,CTNND2,FGFR3,PREX2,LRP1B,ITPR2,FMN2
1.715e-03	-6.37	human chr5p13.2	chromosome location	human chr5p13.2	32	2	26134	50	RANBP3L,SLC1A3
1.732e-03	-6.36	relaxation of muscle	biological process	GO:0090075	23	2	18204	49	ATP1A2,PRKG1
1.750e-03	-6.35	eye	COSMIC cancer mutations	eye	606	7	16828	49	FGFR3,CTNND2,ADCY2,RANBP3L,PCDH9,CPE,PREX2
1.758e-03	-6.34	lung-right_lower_lobe-carcinoma-adenocarcinoma	COSMIC cancer mutations	lung-right_lower_lobe-carcinoma-adenocarcinoma	5692	27	16828	49	CTNND2,ADCY2,CDH20,LSAMP,ATP1A2,PTPRZ1,NTM,GPM6A,CST3,NKAIN3,PRKG1,NPAS3,FBXL7,COL5A3,SLC1A3,GPC5,ITPR2,HPSE2,MGAT4C,ATP13A4,SOX5,GABRB1,FMN2,NRG3,DTNA,LRP1B,NTRK2
1.758e-03	-6.34	right_lower_lobe	COSMIC cancer mutations	right_lower_lobe	5692	27	16828	49	GABRB1,SOX5,HPSE2,MGAT4C,ATP13A4,DTNA,NTRK2,LRP1B,NRG3,FMN2,SLC1A3,COL5A3,GPC5,ITPR2,CST3,NKAIN3,FBXL7,PRKG1,NPAS3,ADCY2,CDH20,CTNND2,GPM6A,PTPRZ1,NTM,ATP1A2,LSAMP
1.781e-03	-6.33	ovary-carcinoma-serous_carcinoma	COSMIC cancer mutations	ovary-carcinoma-serous_carcinoma	10710	41	16828	49	COL5A3,ZBTB20,SLC1A3,NRXN1,ITPR2,GPC5,MGAT4C,MSI2,ATP13A4,HPSE2,GABRB1,SOX5,BMPR1B,FMN2,RORA,PREX2,CADM1,NTRK2,LRP1B,DTNA,NRG3,CTNND2,CDH20,ADCY2,RANBP3L,NTM,PTPRZ1,TNIK,ATP1A2,LSAMP,CPE,PCDH9,SLC1A2,FGFR3,GLIS3,CST3,FBXL7,CSGALNACT1,NPAS3,PRKG1,NHSL1
1.808e-03	-6.32	lung-carcinoma-small_cell_carcinoma	COSMIC cancer mutations	lung-carcinoma-small_cell_carcinoma	9908	39	16828	49	CST3,NKAIN3,FGFR3,CSGALNACT1,FBXL7,PRKG1,NPAS3,ABLIM1,RANBP3L,CDH20,CTNND2,CPE,PCDH9,NTM,PTPRZ1,GPM6A,ATP1A2,TNIK,GABRB1,SOX5,HPSE2,MGAT4C,ATP13A4,MSI2,NTRK2,LRP1B,DTNA,NRG3,PREX2,BMPR1B,FMN2,RORA,NRXN1,SPARCL1,COL5A3,ITPR2,GPC5,NFIA,PITPNC1
1.831e-03	-6.30	small_cell_carcinoma	COSMIC cancer mutations	small_cell_carcinoma	9913	39	16828	49	CPE,PCDH9,TNIK,ATP1A2,GPM6A,NTM,PTPRZ1,RANBP3L,ABLIM1,CDH20,CTNND2,PRKG1,CSGALNACT1,FBXL7,NPAS3,CST3,NKAIN3,FGFR3,ITPR2,GPC5,PITPNC1,NFIA,NRXN1,COL5A3,SPARCL1,NRG3,NTRK2,DTNA,LRP1B,PREX2,BMPR1B,FMN2,RORA,SOX5,GABRB1,HPSE2,ATP13A4,MGAT4C,MSI2
1.832e-03	-6.30	P-type ion transporter activity	molecular function	GO:0015662	24	2	18094	48	ATP1A2,ATP13A4
1.832e-03	-6.30	P-type transmembrane transporter activity	molecular function	GO:0140358	24	2	18094	48	ATP13A4,ATP1A2
1.853e-03	-6.29	postsynaptic specialization	cellular component	GO:0099572	345	5	19108	49	TNIK,GABRB1,NTRK2,CTNND2,CADM1
1.854e-03	-6.29	CASK (calcium/calmodulin dependent serine protein kinase)	protein interactions	8573	204	4	19454	50	CADM1,NRXN1,DTNA,ABLIM1
1.856e-03	-6.29	bone development	biological process	GO:0060348	195	4	18204	49	FGFR3,RANBP3L,CSGALNACT1,BMPR1B
1.913e-03	-6.26	human chr12q21.31-q21.32	chromosome location	human chr12q21.31-q21.32	1	1	26134	50	MGAT4C
1.913e-03	-6.26	human chr2q22.1-q22.2	chromosome location	human chr2q22.1-q22.2	1	1	26134	50	LRP1B
1.913e-03	-6.26	human chr3q26.2-q26.31	chromosome location	human chr3q26.2-q26.31	1	1	26134	50	TNIK
1.913e-03	-6.26	human chr10q11.23-q21.1	chromosome location	human chr10q11.23-q21.1	1	1	26134	50	PRKG1
1.957e-03	-6.24	bone-femur-other-chondroblastoma	COSMIC cancer mutations	bone-femur-other-chondroblastoma	183	4	16828	49	GPC5,LRP1B,NRG3,PCDH9
1.978e-03	-6.23	IGc2	smart domains	SM00408	239	5	9717	37	NTRK2,FGFR3,CADM1,LSAMP,NTM
2.015e-03	-6.21	modulation of chemical synaptic transmission	biological process	GO:0050804	494	6	18204	49	NTRK2,APOE,SLC1A3,ATP1A2,NRG3,NRXN1
2.018e-03	-6.21	back	COSMIC cancer mutations	back	310	5	16828	49	LRP1B,PREX2,ATP1A2,TNIK,FGFR3
2.021e-03	-6.20	skin-face-malignant_melanoma-lentigo_maligna	COSMIC cancer mutations	skin-face-malignant_melanoma-lentigo_maligna	23	2	16828	49	FGFR3,PREX2
2.035e-03	-6.20	regulation of trans-synaptic signaling	biological process	GO:0099177	495	6	18204	49	NTRK2,NRXN1,NRG3,SLC1A3,ATP1A2,APOE
2.047e-03	-6.19	L-glutamate transmembrane transport	biological process	GO:0015813	25	2	18204	49	SLC1A2,SLC1A3
2.141e-03	-6.15	skeletal system development	biological process	GO:0001501	500	6	18204	49	CSGALNACT1,FGFR3,RANBP3L,BMPR1B,NFIA,SOX5
2.174e-03	-6.13	skin-extremity-malignant_melanoma	COSMIC cancer mutations	skin-extremity-malignant_melanoma	1875	13	16828	49	PITPNC1,PCDH9,PTPRZ1,COL5A3,ADCY2,CDH20,FBXL7,FMN2,LRP1B,NTRK2,PREX2,HPSE2,ATP13A4
2.181e-03	-6.13	KCNJ12 (potassium inwardly rectifying channel subfamily J member 12)	protein interactions	3768	27	2	19454	50	ABLIM1,DTNA
2.181e-03	-6.13	Glutamate Neurotransmitter Release Cycle	REACTOME pathways	R-HSA-210500	24	2	10285	30	SLC1A3,SLC1A2
2.182e-03	-6.13	ion binding	molecular function	GO:0043167	6007	26	18094	48	GLIS3,LRP1B,ETNPPL,CPE,SLC1A2,BMPR1B,ABLIM1,PRKG1,ITPR2,FGFR3,PITPNC1,NRXN1,ZBTB20,DTNA,ATP13A4,TNIK,RORA,ATP1A2,SLC1A3,MGAT4C,PCDH9,SPARCL1,ADCY2,NTRK2,CSGALNACT1,APOE
2.214e-03	-6.11	C4-dicarboxylate transport	biological process	GO:0015740	26	2	18204	49	SLC1A3,SLC1A2
2.222e-03	-6.11	upper_aerodigestive_tract-pharynx-carcinoma-nasopharyngeal_carcinoma	COSMIC cancer mutations	upper_aerodigestive_tract-pharynx-carcinoma-nasopharyngeal_carcinoma	1425	11	16828	49	CTNND2,ATP1A2,NFIA,PITPNC1,FGFR3,ATP13A4,SLC1A2,NTRK2,PREX2,FMN2,NHSL1
2.222e-03	-6.11	nasopharyngeal_carcinoma	COSMIC cancer mutations	nasopharyngeal_carcinoma	1425	11	16828	49	CTNND2,NFIA,PITPNC1,ATP1A2,FGFR3,SLC1A2,ATP13A4,FMN2,NHSL1,NTRK2,PREX2
2.226e-03	-6.11	membrane	cellular component	GO:0016020	9220	34	19108	49	BMPR1B,GPM6A,NRG3,CPE,DTNA,ITPR2,ADCY2,CADM1,TNIK,NTRK2,PCDH9,CSGALNACT1,GABRB1,LRP1B,PTPRZ1,CST3,NTM,PRKG1,APOE,FMN2,ATP13A4,LSAMP,MGAT4C,NKAIN3,HPSE2,GPC5,PREX2,ATP1A2,SLC1A2,CTNND2,CDH20,FGFR3,SLC1A3,NRXN1
2.319e-03	-6.07	poly(U) RNA binding	molecular function	GO:0008266	27	2	18094	48	MSI2,RBMS3
2.322e-03	-6.07	adrenal_gland	COSMIC cancer mutations	adrenal_gland	2628	16	16828	49	PTPRZ1,ATP1A2,PCDH9,CTNND2,ZBTB20,ADCY2,CSGALNACT1,FMN2,NHSL1,NTRK2,LRP1B,NRG3,SLC1A2,HPSE2,FGFR3,SOX5
2.322e-03	-6.07	Thyroid hormone synthesis	KEGG pathways	ko04918	74	3	7161	26	ADCY2,ITPR2,ATP1A2
2.322e-03	-6.07	Thyroid hormone synthesis	KEGG pathways	hsa04918	74	3	7161	26	ATP1A2,ITPR2,ADCY2
2.398e-03	-6.03	bone morphogenesis	biological process	GO:0060349	99	3	18204	49	FGFR3,CSGALNACT1,BMPR1B
2.412e-03	-6.03	acute_myeloid_leukaemia	COSMIC cancer mutations	acute_myeloid_leukaemia	10418	40	16828	49	CDH20,RANBP3L,ADCY2,ABLIM1,CTNND2,LSAMP,ATP1A2,TNIK,NTM,PTPRZ1,CPE,PCDH9,GLIS3,NKAIN3,SLC1A2,RBMS3,NHSL1,PRKG1,FBXL7,NPAS3,CSGALNACT1,SLC1A3,NRXN1,COL5A3,SPARCL1,NFIA,GPC5,ITPR2,SOX5,GABRB1,MSI2,ATP13A4,HPSE2,PREX2,NRG3,CADM1,NTRK2,LRP1B,FMN2,RORA
2.412e-03	-6.03	haematopoietic_and_lymphoid_tissue-haematopoietic_neoplasm-acute_myeloid_leukaemia	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue-haematopoietic_neoplasm-acute_myeloid_leukaemia	10418	40	16828	49	COL5A3,SPARCL1,NRXN1,SLC1A3,ITPR2,GPC5,NFIA,HPSE2,ATP13A4,MSI2,SOX5,GABRB1,RORA,FMN2,NRG3,NTRK2,CADM1,LRP1B,PREX2,CTNND2,RANBP3L,ABLIM1,ADCY2,CDH20,PCDH9,CPE,LSAMP,TNIK,ATP1A2,NTM,PTPRZ1,SLC1A2,GLIS3,NKAIN3,NHSL1,FBXL7,NPAS3,PRKG1,CSGALNACT1,RBMS3
2.413e-03	-6.03	Gastric acid secretion	KEGG pathways	ko04971	75	3	7161	26	ITPR2,ADCY2,ATP1A2
2.413e-03	-6.03	Gastric acid secretion	KEGG pathways	hsa04971	75	3	7161	26	ATP1A2,ADCY2,ITPR2
2.478e-03	-6.00	Calcium-transporting ATPase, transmembrane domain	gene3d domains	1.20.1110.10	25	2	14470	43	ATP13A4,ATP1A2
2.490e-03	-6.00	autonomic_ganglia	COSMIC cancer mutations	autonomic_ganglia	4005	21	16828	49	PITPNC1,NFIA,PCDH9,TNIK,ATP1A2,PTPRZ1,GPM6A,CTNND2,COL5A3,ADCY2,FMN2,NHSL1,NPAS3,PRKG1,FBXL7,NTRK2,LRP1B,PREX2,FGFR3,SLC1A2,GLIS3
2.535e-03	-5.98	signaling	biological process	GO:0023052	4968	23	18204	49	FGFR3,SLC1A3,FMN2,GABRB1,RORA,PITPNC1,ADCY2,PREX2,PRKG1,SLC1A2,NFIA,DTNA,APOE,SPARCL1,NTRK2,TNIK,NRXN1,ATP1A2,NRG3,CPE,CTNND2,BMPR1B,ITPR2
2.569e-03	-5.96	PROKAR_LIPOPROTEIN	prosite domains	PS51257	76	3	12186	44	APOE,GLIS3,CPE
2.570e-03	-5.96	Dcaf7 (DDB1 and CUL4 associated factor 7)	protein interactions	71833	1	1	19454	50	BMPR1B
2.570e-03	-5.96	Hipk3 (homeodomain interacting protein kinase 3)	protein interactions	15259	1	1	19454	50	GLIS3
2.570e-03	-5.96	Agtrap (angiotensin II, type I receptor-associated protein)	protein interactions	11610	1	1	19454	50	PITPNC1
2.570e-03	-5.96	App (amyloid beta precursor protein)	protein interactions	100689222	1	1	19454	50	LRP1B
2.570e-03	-5.96	Isl1 (ISL1 transcription factor, LIM/homeodomain)	protein interactions	16392	1	1	19454	50	GLIS3
2.570e-03	-5.96	1700006A11Rik (RIKEN cDNA 1700006A11 gene)	protein interactions	71824	1	1	19454	50	BMPR1B
2.570e-03	-5.96	Sytl1 (synaptotagmin-like 1)	protein interactions	269589	1	1	19454	50	NRXN1
2.570e-03	-5.96	Lztr1 (leucine-zipper-like transcriptional regulator, 1)	protein interactions	66863	1	1	19454	50	BMPR1B
2.570e-03	-5.96	Bdnf (brain derived neurotrophic factor)	protein interactions	12064	1	1	19454	50	NTRK2
2.570e-03	-5.96	fgf3.L (fibroblast growth factor 3 L homeolog)	protein interactions	373669	1	1	19454	50	FGFR3
2.570e-03	-5.96	Dynlt1 (dynein light chain Tctex-type 1)	protein interactions	83462	1	1	19454	50	NTRK2
2.570e-03	-5.96	Sh2b1 (SH2B adaptor protein 1)	protein interactions	20399	1	1	19454	50	FGFR3
2.616e-03	-5.95	cGMP-PKG signaling pathway	KEGG pathways	ko04022	163	4	7161	26	ADCY2,ITPR2,PRKG1,ATP1A2
2.616e-03	-5.95	cGMP-PKG signaling pathway	KEGG pathways	hsa04022	163	4	7161	26	ATP1A2,PRKG1,ITPR2,ADCY2
2.653e-03	-5.93	ethanolamine-phosphate phospho-lyase activity	molecular function	GO:0050459	1	1	18094	48	ETNPPL
2.653e-03	-5.93	peptidoglycan glycosyltransferase activity	molecular function	GO:0008955	1	1	18094	48	CSGALNACT1
2.653e-03	-5.93	brain-derived neurotrophic factor receptor activity	molecular function	GO:0060175	1	1	18094	48	NTRK2
2.653e-03	-5.93	metal chelating activity	molecular function	GO:0046911	1	1	18094	48	APOE
2.673e-03	-5.92	amino acid:monoatomic cation symporter activity	molecular function	GO:0005416	29	2	18094	48	SLC1A2,SLC1A3
2.692e-03	-5.92	directional guidance of interneurons involved in migration from the subpallium to the cortex	biological process	GO:0021840	1	1	18204	49	NRG3
2.692e-03	-5.92	positive regulation of lipid transport across blood-brain barrier	biological process	GO:1903002	1	1	18204	49	APOE
2.692e-03	-5.92	chemorepulsion involved in interneuron migration from the subpallium to the cortex	biological process	GO:0021842	1	1	18204	49	NRG3
2.692e-03	-5.92	regulation of lipid transport across blood-brain barrier	biological process	GO:1903000	1	1	18204	49	APOE
2.692e-03	-5.92	regulation of transport across blood-brain barrier	biological process	GO:0150200	1	1	18204	49	APOE
2.692e-03	-5.92	negative regulation of collagen catabolic process	biological process	GO:0010711	1	1	18204	49	CST3
2.692e-03	-5.92	negative regulation of calcium:sodium antiporter activity	biological process	GO:1903280	1	1	18204	49	ATP1A2
2.692e-03	-5.92	positive regulation of transport across blood-brain barrier	biological process	GO:0150201	1	1	18204	49	APOE
2.692e-03	-5.92	olfactory cortex development	biological process	GO:0021989	1	1	18204	49	ATP1A2
2.692e-03	-5.92	regulation of heparan sulfate proteoglycan binding	biological process	GO:1905858	1	1	18204	49	APOE
2.692e-03	-5.92	positive regulation of heparan sulfate proteoglycan binding	biological process	GO:1905860	1	1	18204	49	APOE
2.692e-03	-5.92	homologous chromosome movement towards spindle pole in meiosis I anaphase	biological process	GO:0051758	1	1	18204	49	FMN2
2.692e-03	-5.92	regulation of cellular response to very-low-density lipoprotein particle stimulus	biological process	GO:1905890	1	1	18204	49	APOE
2.692e-03	-5.92	negative regulation of elastin catabolic process	biological process	GO:0060311	1	1	18204	49	CST3
2.692e-03	-5.92	trans-synaptic signaling by neuropeptide	biological process	GO:0099540	1	1	18204	49	NTRK2
2.692e-03	-5.92	trans-synaptic signaling by neuropeptide, modulating synaptic transmission	biological process	GO:0099551	1	1	18204	49	NTRK2
2.692e-03	-5.92	intermediate-density lipoprotein particle clearance	biological process	GO:0071831	1	1	18204	49	APOE
2.700e-03	-5.91	M14_CPE_CPD	interpro domains	IPR034232	1	1	18521	50	CPE
2.700e-03	-5.91	RBMS3_RRM2	interpro domains	IPR034406	1	1	18521	50	RBMS3
2.700e-03	-5.91	NTRK2	interpro domains	IPR020455	1	1	18521	50	NTRK2
2.700e-03	-5.91	PKcGMP_CC	interpro domains	IPR031831	1	1	18521	50	PRKG1
2.700e-03	-5.91	SPARC-like_p1	interpro domains	IPR016359	1	1	18521	50	SPARCL1
2.700e-03	-5.91	Rex2_DEP_1	interpro domains	IPR037367	1	1	18521	50	PREX2
2.751e-03	-5.90	cGMP-mediated signaling	biological process	GO:0019934	29	2	18204	49	PRKG1,APOE
2.751e-03	-5.90	negative regulation of amyloid-beta formation	biological process	GO:1902430	29	2	18204	49	APOE,NTRK2
2.751e-03	-5.90	postsynaptic membrane organization	biological process	GO:0001941	29	2	18204	49	NRXN1,APOE
2.754e-03	-5.89	FGFR3_TM	pfam domains	PF21165	1	1	17795	49	FGFR3
2.754e-03	-5.89	PKcGMP_CC	pfam domains	PF16808	1	1	17795	49	PRKG1
2.758e-03	-5.89	regulation of steroid metabolic process	biological process	GO:0019218	104	3	18204	49	APOE,RORA,PRKG1
2.834e-03	-5.87	neural precursor cell proliferation	biological process	GO:0061351	105	3	18204	49	NFIA,SOX5,RORA
2.853e-03	-5.86	cell communication	biological process	GO:0007154	5010	23	18204	49	NFIA,SLC1A2,PRKG1,PREX2,ADCY2,PITPNC1,RORA,GABRB1,FMN2,SLC1A3,FGFR3,ITPR2,BMPR1B,CTNND2,CPE,NRG3,ATP1A2,TNIK,NRXN1,NTRK2,SPARCL1,APOE,DTNA
2.859e-03	-5.86	poly-pyrimidine tract binding	molecular function	GO:0008187	30	2	18094	48	MSI2,RBMS3
2.866e-03	-5.85	beta-catenin binding	molecular function	GO:0008013	107	3	18094	48	CTNND2,CDH20,RORA
2.870e-03	-5.85	SH2B1 (SH2B adaptor protein 1)	protein interactions	25970	31	2	19454	50	FGFR3,NTRK2
2.917e-03	-5.84	t(4;14) translocations of FGFR3	REACTOME pathways	R-HSA-2033515	1	1	10285	30	FGFR3
2.934e-03	-5.83	extracellular matrix	cellular component	GO:0031012	559	6	19108	49	PTPRZ1,APOE,HPSE2,GPC5,SPARCL1,COL5A3
2.942e-03	-5.83	L-glutamate import	biological process	GO:0051938	30	2	18204	49	SLC1A2,SLC1A3
2.954e-03	-5.82	ovary-carcinoma-clear_cell_carcinoma	COSMIC cancer mutations	ovary-carcinoma-clear_cell_carcinoma	665	7	16828	49	PRKG1,BMPR1B,TNIK,NTRK2,LRP1B,SPARCL1,FGFR3
2.960e-03	-5.82	external encapsulating structure	cellular component	GO:0030312	560	6	19108	49	APOE,PTPRZ1,SPARCL1,COL5A3,HPSE2,GPC5
2.972e-03	-5.82	-	gene3d domains	6.10.250.1740	1	1	14470	43	FGFR3
3.042e-03	-5.80	presynaptic active zone membrane	cellular component	GO:0048787	32	2	19108	49	GABRB1,GPM6A
3.055e-03	-5.79	clear_cell_carcinoma	COSMIC cancer mutations	clear_cell_carcinoma	669	7	16828	49	BMPR1B,PRKG1,TNIK,LRP1B,NTRK2,SPARCL1,FGFR3
3.057e-03	-5.79	NXPH2 (neurexophilin 2)	protein interactions	11249	32	2	19454	50	PCDH9,NRXN1
3.065e-03	-5.79	brain development	biological process	GO:0007420	724	7	18204	49	ATP1A2,PCDH9,NRG3,SLC1A2,PRKG1,RORA,NTRK2
3.072e-03	-5.79	upper_aerodigestive_tract-pharynx-carcinoma-squamous_cell_carcinoma	COSMIC cancer mutations	upper_aerodigestive_tract-pharynx-carcinoma-squamous_cell_carcinoma	1485	11	16828	49	PCDH9,NRG3,DTNA,LRP1B,PREX2,PTPRZ1,FMN2,NPAS3,GPC5,GABRB1,FGFR3
3.095e-03	-5.78	Neuronal System	REACTOME pathways	R-HSA-112316	349	5	10285	30	ADCY2,NRXN1,GABRB1,SLC1A2,SLC1A3
3.132e-03	-5.77	acute_lymphoblastic_leukaemia	COSMIC cancer mutations	acute_lymphoblastic_leukaemia	2197	14	16828	49	TNIK,ATP1A2,PTPRZ1,NFIA,ADCY2,PREX2,CADM1,LRP1B,NTRK2,DTNA,BMPR1B,PRKG1,SOX5,FGFR3
3.140e-03	-5.76	negative regulation of amyloid precursor protein catabolic process	biological process	GO:1902992	31	2	18204	49	NTRK2,APOE
3.140e-03	-5.76	endochondral ossification	biological process	GO:0001958	31	2	18204	49	FGFR3,CSGALNACT1
3.140e-03	-5.76	replacement ossification	biological process	GO:0036075	31	2	18204	49	CSGALNACT1,FGFR3
3.149e-03	-5.76	postsynapse organization	biological process	GO:0099173	109	3	18204	49	APOE,NRXN1,CTNND2
3.202e-03	-5.74	presynapse	cellular component	GO:0098793	569	6	19108	49	SLC1A2,GPM6A,GABRB1,TNIK,NTRK2,NRXN1
3.266e-03	-5.72	skeletal system morphogenesis	biological process	GO:0048705	228	4	18204	49	BMPR1B,SOX5,FGFR3,CSGALNACT1
3.282e-03	-5.72	E1-E2_ATPase	pfam domains	PF00122	31	2	17795	49	ATP13A4,ATP1A2
3.289e-03	-5.72	stomach-carcinoma-diffuse_adenocarcinoma	COSMIC cancer mutations	stomach-carcinoma-diffuse_adenocarcinoma	4383	22	16828	49	SLC1A3,GABRB1,SOX5,MGAT4C,PREX2,DTNA,LRP1B,CADM1,NRG3,FMN2,ADCY2,ABLIM1,RANBP3L,CTNND2,PTPRZ1,GPM6A,ATP1A2,PCDH9,GLIS3,FGFR3,PRKG1,NHSL1
3.289e-03	-5.72	diffuse_adenocarcinoma	COSMIC cancer mutations	diffuse_adenocarcinoma	4383	22	16828	49	ATP1A2,PTPRZ1,GPM6A,PCDH9,SLC1A3,RANBP3L,ABLIM1,ADCY2,CTNND2,PREX2,NRG3,CADM1,DTNA,LRP1B,NHSL1,FMN2,PRKG1,GLIS3,SOX5,GABRB1,MGAT4C,FGFR3
3.315e-03	-5.71	cell-cell adhesion	biological process	GO:0098609	546	6	18204	49	SPARCL1,CDH20,PCDH9,NRXN1,CADM1,CTNND2
3.344e-03	-5.70	transepithelial transport	biological process	GO:0070633	32	2	18204	49	SLC1A2,SLC1A3
3.344e-03	-5.70	positive regulation of cartilage development	biological process	GO:0061036	32	2	18204	49	BMPR1B,SOX5
3.349e-03	-5.70	oesophagus-middle_third-carcinoma-squamous_cell_carcinoma	COSMIC cancer mutations	oesophagus-middle_third-carcinoma-squamous_cell_carcinoma	3531	19	16828	49	NRG3,LRP1B,PREX2,FMN2,NHSL1,SOX5,HPSE2,PCDH9,ATP1A2,TNIK,PTPRZ1,GPM6A,GPC5,ADCY2,ABLIM1,ZBTB20,COL5A3,CTNND2,SPARCL1
3.371e-03	-5.69	middle_third	COSMIC cancer mutations	middle_third	3533	19	16828	49	PREX2,NRG3,LRP1B,FMN2,NHSL1,SOX5,HPSE2,ATP1A2,TNIK,PTPRZ1,GPM6A,PCDH9,GPC5,ZBTB20,ABLIM1,ADCY2,CTNND2,COL5A3,SPARCL1
3.387e-03	-5.69	atypical_teratoid-rhabdoid_tumour	COSMIC cancer mutations	atypical_teratoid-rhabdoid_tumour	213	4	16828	49	PCDH9,GABRB1,FMN2,FGFR3
3.387e-03	-5.69	central_nervous_system-brain-atypical_teratoid-rhabdoid_tumour	COSMIC cancer mutations	central_nervous_system-brain-atypical_teratoid-rhabdoid_tumour	213	4	16828	49	GABRB1,PCDH9,FGFR3,FMN2
3.401e-03	-5.68	Protein_kinase_ATP_BS	interpro domains	IPR017441	377	5	18521	50	NTRK2,FGFR3,TNIK,PRKG1,BMPR1B
3.430e-03	-5.68	lentigo_maligna	COSMIC cancer mutations	lentigo_maligna	30	2	16828	49	PREX2,FGFR3
3.430e-03	-5.68	skin-malignant_melanoma-acral_lentiginous	COSMIC cancer mutations	skin-malignant_melanoma-acral_lentiginous	30	2	16828	49	FGFR3,PREX2
3.434e-03	-5.67	Transmission across Chemical Synapses	REACTOME pathways	R-HSA-112315	217	4	10285	30	SLC1A2,SLC1A3,GABRB1,ADCY2
3.472e-03	-5.66	monoatomic ion transmembrane transporter activity	molecular function	GO:0015075	752	7	18094	48	SLC1A2,GPM6A,ATP13A4,ATP1A2,ITPR2,SLC1A3,GABRB1
3.482e-03	-5.66	cell adhesion molecule binding	molecular function	GO:0050839	560	6	18094	48	CTNND2,CADM1,CDH20,PTPRZ1,NRXN1,CPE
3.486e-03	-5.66	dendrite development	biological process	GO:0016358	113	3	18204	49	PREX2,PRKG1,CTNND2
3.495e-03	-5.66	Cation_ATPase	pfam domains	PF13246	32	2	17795	49	ATP13A4,ATP1A2
3.565e-03	-5.64	small molecule binding	molecular function	GO:0036094	6197	26	18094	48	ETNPPL,SLC1A2,CPE,ABLIM1,BMPR1B,GLIS3,LRP1B,FGFR3,ZBTB20,PITPNC1,NRXN1,DTNA,ATP13A4,PRKG1,ITPR2,PCDH9,RORA,TNIK,SLC1A3,ATP1A2,MGAT4C,ADCY2,APOE,CSGALNACT1,NTRK2,SPARCL1
3.621e-03	-5.62	serous_carcinoma	COSMIC cancer mutations	serous_carcinoma	10987	41	16828	49	COL5A3,NRXN1,ZBTB20,SLC1A3,ITPR2,GPC5,HPSE2,MSI2,MGAT4C,ATP13A4,GABRB1,SOX5,RORA,FMN2,BMPR1B,LRP1B,DTNA,NTRK2,CADM1,NRG3,PREX2,CTNND2,ADCY2,RANBP3L,CDH20,CPE,PCDH9,NTM,PTPRZ1,TNIK,LSAMP,ATP1A2,FGFR3,SLC1A2,CST3,GLIS3,PRKG1,NPAS3,FBXL7,CSGALNACT1,NHSL1
3.649e-03	-5.61	TPRA1 (transmembrane protein adipocyte associated 1)	protein interactions	131601	35	2	19454	50	BMPR1B,ITPR2
3.653e-03	-5.61	response to endogenous stimulus	biological process	GO:0009719	1402	10	18204	49	BMPR1B,NFIA,SLC1A2,ITPR2,ATP1A2,SOX5,NTRK2,SLC1A3,FGFR3,GABRB1
3.769e-03	-5.58	exploration behavior	biological process	GO:0035640	34	2	18204	49	APOE,ATP1A2
3.769e-03	-5.58	negative regulation of amide metabolic process	biological process	GO:0034249	34	2	18204	49	APOE,NTRK2
3.801e-03	-5.57	Gap junction	KEGG pathways	ko04540	88	3	7161	26	ITPR2,ADCY2,PRKG1
3.801e-03	-5.57	Gap junction	KEGG pathways	hsa04540	88	3	7161	26	PRKG1,ITPR2,ADCY2
3.815e-03	-5.57	metal ion binding	molecular function	GO:0046872	4239	20	18094	48	SLC1A2,CPE,PCDH9,ABLIM1,BMPR1B,RORA,SLC1A3,ATP1A2,MGAT4C,LRP1B,GLIS3,ADCY2,ZBTB20,NRXN1,APOE,CSGALNACT1,ATP13A4,DTNA,ITPR2,SPARCL1
3.826e-03	-5.57	NTKRECEPTOR2	prints domains	PR01941	1	1	5227	20	NTRK2
3.878e-03	-5.55	organic acid:sodium symporter activity	molecular function	GO:0005343	35	2	18094	48	SLC1A3,SLC1A2
3.937e-03	-5.54	synapse assembly	biological process	GO:0007416	118	3	18204	49	GPM6A,NRG3,NRXN1
4.071e-03	-5.50	PADI3 (peptidyl arginine deiminase 3)	protein interactions	51702	37	2	19454	50	SPARCL1,CSGALNACT1
4.071e-03	-5.50	HPCA (hippocalcin)	protein interactions	3208	37	2	19454	50	CST3,GPM6A
4.094e-03	-5.50	transporter activity	molecular function	GO:0005215	1211	9	18094	48	PITPNC1,SLC1A2,GPM6A,ATP13A4,APOE,ATP1A2,ITPR2,SLC1A3,GABRB1
4.102e-03	-5.50	Ig_sub	interpro domains	IPR003599	394	5	18521	50	CADM1,LSAMP,NTRK2,NTM,FGFR3
4.244e-03	-5.46	P_typ_ATPase	interpro domains	IPR001757	36	2	18521	50	ATP1A2,ATP13A4
4.244e-03	-5.46	ATPase_P-typ_cyto_dom_N	interpro domains	IPR023299	36	2	18521	50	ATP1A2,ATP13A4
4.244e-03	-5.46	ATPase_P-typ_transduc_dom_A_sf	interpro domains	IPR008250	36	2	18521	50	ATP1A2,ATP13A4
4.244e-03	-5.46	P_typ_ATPase_HD_dom	interpro domains	IPR044492	36	2	18521	50	ATP13A4,ATP1A2
4.244e-03	-5.46	ATPase_P-typ_P_site	interpro domains	IPR018303	36	2	18521	50	ATP13A4,ATP1A2
4.281e-03	-5.45	regulation of synapse organization	biological process	GO:0050807	246	4	18204	49	NTRK2,NRXN1,APOE,GPM6A
4.335e-03	-5.44	kidney-other-neoplasm	COSMIC cancer mutations	kidney-other-neoplasm	10653	40	16828	49	CTNND2,CDH20,ABLIM1,ADCY2,RANBP3L,PTPRZ1,GPM6A,ATP1A2,LSAMP,TNIK,PCDH9,CPE,SLC1A2,FGFR3,NKAIN3,CSGALNACT1,NPAS3,PRKG1,FBXL7,NHSL1,SPARCL1,COL5A3,ZBTB20,SLC1A3,NRXN1,ITPR2,GPC5,ATP13A4,MGAT4C,HPSE2,GABRB1,SOX5,FMN2,RORA,PREX2,DTNA,NTRK2,LRP1B,CADM1,NRG3
4.354e-03	-5.44	DAG and IP3 signaling	REACTOME pathways	R-HSA-1489509	34	2	10285	30	ITPR2,ADCY2
4.427e-03	-5.42	head development	biological process	GO:0060322	774	7	18204	49	NTRK2,SLC1A2,PRKG1,RORA,ATP1A2,NRG3,PCDH9
4.432e-03	-5.42	chondroitin biosynthesis	BIOCYC pathways	HUMAN_PWY-6566	2	1	902	2	CSGALNACT1
4.448e-03	-5.42	central_nervous_system-brainstem-glioma-oligoastrocytoma_Grade_III	COSMIC cancer mutations	central_nervous_system-brainstem-glioma-oligoastrocytoma_Grade_III	114	3	16828	49	PREX2,SOX5,SLC1A2
4.448e-03	-5.42	Lima1 (LIM domain and actin binding 1)	protein interactions	65970	129	3	19454	50	ZBTB20,ITPR2,ABLIM1
4.478e-03	-5.41	ATPase_P-typ_TM_dom_sf	interpro domains	IPR023298	37	2	18521	50	ATP1A2,ATP13A4
4.543e-03	-5.39	animal organ morphogenesis	biological process	GO:0009887	988	8	18204	49	NTRK2,BMPR1B,CSGALNACT1,ABLIM1,CPE,NRG3,FGFR3,SOX5
4.616e-03	-5.38	kidney-carcinoma-papillary_renal_cell_carcinoma	COSMIC cancer mutations	kidney-carcinoma-papillary_renal_cell_carcinoma	6364	28	16828	49	FGFR3,PRKG1,CTNND2,ADCY2,ABLIM1,CPE,PTPRZ1,NTM,ATP1A2,TNIK,HPSE2,ATP13A4,GABRB1,SOX5,FMN2,RORA,BMPR1B,CADM1,NTRK2,LRP1B,NRG3,PREX2,NRXN1,ZBTB20,GPC5,ITPR2,NFIA,PITPNC1
4.616e-03	-5.38	papillary_renal_cell_carcinoma	COSMIC cancer mutations	papillary_renal_cell_carcinoma	6364	28	16828	49	ZBTB20,NRXN1,PITPNC1,NFIA,GPC5,ITPR2,ATP13A4,HPSE2,SOX5,GABRB1,FMN2,RORA,BMPR1B,PREX2,NRG3,LRP1B,NTRK2,CADM1,CTNND2,ADCY2,ABLIM1,TNIK,ATP1A2,PTPRZ1,NTM,CPE,FGFR3,PRKG1
4.630e-03	-5.38	adenoid_cystic_carcinoma	COSMIC cancer mutations	adenoid_cystic_carcinoma	1123	9	16828	49	PRKG1,RORA,LRP1B,NTRK2,TNIK,FGFR3,MGAT4C,CTNND2,GABRB1
4.632e-03	-5.37	prostate-carcinoma-adenocarcinoma	COSMIC cancer mutations	prostate-carcinoma-adenocarcinoma	12379	44	16828	49	SPARCL1,COL5A3,SLC1A3,NRXN1,NFIA,PITPNC1,ITPR2,ATP13A4,SOX5,BMPR1B,RORA,NRG3,CDH20,ADCY2,RANBP3L,GPM6A,PTPRZ1,ATP1A2,PCDH9,CPE,SLC1A2,CSGALNACT1,ZBTB20,GPC5,MGAT4C,HPSE2,GABRB1,FMN2,PREX2,NTRK2,CADM1,LRP1B,CTNND2,ABLIM1,NTM,LSAMP,TNIK,FGFR3,NKAIN3,GLIS3,PRKG1,NPAS3,FBXL7,NHSL1
4.662e-03	-5.37	regulation of synapse structure or activity	biological process	GO:0050803	252	4	18204	49	NRXN1,GPM6A,APOE,NTRK2
4.674e-03	-5.37	collagen-containing extracellular matrix	cellular component	GO:0062023	428	5	19108	49	GPC5,COL5A3,SPARCL1,PTPRZ1,APOE
4.691e-03	-5.36	amino acid import across plasma membrane	biological process	GO:0089718	38	2	18204	49	SLC1A2,SLC1A3
4.714e-03	-5.36	Pancreatic secretion	KEGG pathways	ko04972	95	3	7161	26	ATP1A2,ADCY2,ITPR2
4.714e-03	-5.36	Pancreatic secretion	KEGG pathways	hsa04972	95	3	7161	26	ADCY2,ITPR2,ATP1A2
4.815e-03	-5.34	kidney-Wilms_tumour	COSMIC cancer mutations	kidney-Wilms_tumour	545	6	16828	49	PRKG1,BMPR1B,FMN2,TNIK,NTRK2,FGFR3
4.816e-03	-5.34	NGF signalling via TRKA from the plasma membrane	REACTOME pathways	R-HSA-187037	387	5	10285	30	NRG3,ITPR2,ADCY2,FGFR3,NTRK2
4.816e-03	-5.34	biliary_tract-gallbladder-carcinoma-adenocarcinoma	COSMIC cancer mutations	biliary_tract-gallbladder-carcinoma-adenocarcinoma	2821	16	16828	49	NHSL1,FMN2,PRKG1,PREX2,NRG3,LRP1B,FGFR3,NKAIN3,PITPNC1,ITPR2,TNIK,PTPRZ1,PCDH9,COL5A3,CTNND2,SPARCL1
4.816e-03	-5.34	gallbladder	COSMIC cancer mutations	gallbladder	2821	16	16828	49	CTNND2,COL5A3,SPARCL1,ITPR2,PITPNC1,PCDH9,TNIK,PTPRZ1,FGFR3,NKAIN3,NHSL1,FMN2,PRKG1,NRG3,LRP1B,PREX2
4.835e-03	-5.33	skin-head_neck-malignant_melanoma-superficial_spreading	COSMIC cancer mutations	skin-head_neck-malignant_melanoma-superficial_spreading	923	8	16828	49	GABRB1,ADCY2,ATP13A4,MGAT4C,COL5A3,CTNND2,LRP1B,PREX2
4.858e-03	-5.33	Wilms_tumour	COSMIC cancer mutations	Wilms_tumour	546	6	16828	49	PRKG1,FMN2,BMPR1B,TNIK,NTRK2,FGFR3
4.872e-03	-5.32	EGFR interacts with phospholipase C-gamma	REACTOME pathways	R-HSA-212718	36	2	10285	30	ITPR2,ADCY2
4.872e-03	-5.32	PLC-gamma1 signalling	REACTOME pathways	R-HSA-167021	36	2	10285	30	ITPR2,ADCY2
4.936e-03	-5.31	sodium ion homeostasis	biological process	GO:0055078	39	2	18204	49	SLC1A3,ATP1A2
4.936e-03	-5.31	cellular response to alkaloid	biological process	GO:0071312	39	2	18204	49	SLC1A2,SLC1A3
4.945e-03	-5.31	NUFIP1 (nuclear FMR1 interacting protein 1)	protein interactions	26747	134	3	19454	50	GPM6A,NTM,CPE
5.049e-03	-5.29	NTRK2 (neurotrophic receptor tyrosine kinase 2)	protein interactions	4915	135	3	19454	50	DTNA,ABLIM1,NTRK2
5.078e-03	-5.28	salivary_gland	COSMIC cancer mutations	salivary_gland	1139	9	16828	49	GABRB1,MGAT4C,CTNND2,FGFR3,TNIK,NTRK2,LRP1B,PRKG1,RORA
5.090e-03	-5.28	cation binding	molecular function	GO:0043169	4341	20	18094	48	APOE,CSGALNACT1,ATP13A4,DTNA,ZBTB20,NRXN1,ADCY2,SPARCL1,ITPR2,ABLIM1,BMPR1B,PCDH9,SLC1A2,CPE,MGAT4C,GLIS3,LRP1B,SLC1A3,ATP1A2,RORA
5.097e-03	-5.28	Calcium-transporting ATPase, cytoplasmic domain N	gene3d domains	3.40.1110.10	36	2	14470	43	ATP1A2,ATP13A4
5.097e-03	-5.28	Calcium-transporting ATPase, cytoplasmic transduction domain A	gene3d domains	2.70.150.10	36	2	14470	43	ATP1A2,ATP13A4
5.122e-03	-5.27	chylomicron remnant	cellular component	GO:0034360	2	1	19108	49	APOE
5.122e-03	-5.27	discoidal high-density lipoprotein particle	cellular component	GO:0034365	2	1	19108	49	APOE
5.134e-03	-5.27	Klhl1 (kelch-like 1)	protein interactions	93688	2	1	19454	50	BMPR1B
5.134e-03	-5.27	Irf7 (interferon regulatory factor 7)	protein interactions	54123	2	1	19454	50	BMPR1B
5.134e-03	-5.27	Zmym2 (zinc finger, MYM-type 2)	protein interactions	76007	2	1	19454	50	GLIS3
5.134e-03	-5.27	Bmpr2 (bone morphogenetic protein receptor type 2)	protein interactions	12168	2	1	19454	50	BMPR1B
5.134e-03	-5.27	Kdm4c (lysine (K)-specific demethylase 4C)	protein interactions	76804	2	1	19454	50	GLIS3
5.134e-03	-5.27	Fkbp1a (FK506 binding protein 1a)	protein interactions	14225	2	1	19454	50	BMPR1B
5.134e-03	-5.27	Ppp3cc (protein phosphatase 3, catalytic subunit, gamma isoform)	protein interactions	19057	2	1	19454	50	BMPR1B
5.134e-03	-5.27	Fkbp1b (FK506 binding protein 1b)	protein interactions	14226	2	1	19454	50	BMPR1B
5.134e-03	-5.27	Mknk2 (MAP kinase-interacting serine/threonine kinase 2)	protein interactions	17347	2	1	19454	50	BMPR1B
5.134e-03	-5.27	Fbxo34 (F-box protein 34)	protein interactions	78938	2	1	19454	50	BMPR1B
5.134e-03	-5.27	Bcr (BCR activator of RhoGEF and GTPase)	protein interactions	110279	2	1	19454	50	BMPR1B
5.134e-03	-5.27	Sh3kbp1 (SH3-domain kinase binding protein 1)	protein interactions	58194	2	1	19454	50	BMPR1B
5.134e-03	-5.27	TRIM39-RPP21 (TRIM39-RPP21 readthrough)	protein interactions	202658	2	1	19454	50	PRKG1
5.135e-03	-5.27	prostate	COSMIC cancer mutations	prostate	13883	47	16828	49	SOX5,ATP13A4,NRG3,BMPR1B,RORA,SLC1A3,NRXN1,SPARCL1,COL5A3,NFIA,PITPNC1,ITPR2,SLC1A2,CSGALNACT1,CDH20,ADCY2,RANBP3L,PTPRZ1,GPM6A,ATP1A2,PCDH9,CPE,GABRB1,MGAT4C,MSI2,HPSE2,PREX2,NTRK2,LRP1B,DTNA,CADM1,FMN2,ZBTB20,GPC5,NKAIN3,GLIS3,FGFR3,NPAS3,FBXL7,PRKG1,NHSL1,ABLIM1,CTNND2,NTM,TNIK,LSAMP,APOE
5.154e-03	-5.27	spindle	COSMIC cancer mutations	spindle	386	5	16828	49	PREX2,CPE,PCDH9,CTNND2,FGFR3
5.157e-03	-5.27	ovary-carcinoma	COSMIC cancer mutations	ovary-carcinoma	933	8	16828	49	NTRK2,ATP1A2,TNIK,PREX2,BMPR1B,ITPR2,PRKG1,FGFR3
5.187e-03	-5.26	cyclic purine nucleotide metabolic process	biological process	GO:0052652	40	2	18204	49	ADCY2,RORA
5.251e-03	-5.25	oligoastrocytoma_Grade_II	COSMIC cancer mutations	oligoastrocytoma_Grade_II	121	3	16828	49	DTNA,CDH20,FGFR3
5.276e-03	-5.24	cell-cell adhesion via plasma-membrane adhesion molecules	biological process	GO:0098742	261	4	18204	49	CDH20,SPARCL1,PCDH9,CADM1
5.299e-03	-5.24	heparanase activity	molecular function	GO:0030305	2	1	18094	48	HPSE2
5.299e-03	-5.24	G protein-coupled neurotransmitter receptor activity involved in regulation of presynaptic membrane potential	molecular function	GO:0150047	2	1	18094	48	GABRB1
5.299e-03	-5.24	cGMP-dependent protein kinase activity	molecular function	GO:0004692	2	1	18094	48	PRKG1
5.302e-03	-5.24	lung-left_upper_lobe-carcinoma-adenocarcinoma	COSMIC cancer mutations	lung-left_upper_lobe-carcinoma-adenocarcinoma	556	6	16828	49	NTRK2,LRP1B,PRKG1,FBXL7,ADCY2,CTNND2
5.376e-03	-5.23	negative regulation of blood vessel remodeling	biological process	GO:0060313	2	1	18204	49	CST3
5.376e-03	-5.23	chondroitin sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process	biological process	GO:0050653	2	1	18204	49	CSGALNACT1
5.376e-03	-5.23	mesenchymal cell differentiation involved in bone development	biological process	GO:1901706	2	1	18204	49	RANBP3L
5.376e-03	-5.23	fibroblast growth factor receptor apoptotic signaling pathway	biological process	GO:1902178	2	1	18204	49	FGFR3
5.376e-03	-5.23	negative regulation of inositol phosphate biosynthetic process	biological process	GO:0010920	2	1	18204	49	PRKG1
5.376e-03	-5.23	negative regulation of ERBB4 signaling pathway	biological process	GO:0120154	2	1	18204	49	CADM1
5.376e-03	-5.23	UDP-glucuronate metabolic process	biological process	GO:0046398	2	1	18204	49	CSGALNACT1
5.376e-03	-5.23	regulation of elastin catabolic process	biological process	GO:0060310	2	1	18204	49	CST3
5.376e-03	-5.23	lipid transport involved in lipid storage	biological process	GO:0010877	2	1	18204	49	APOE
5.383e-03	-5.22	amino acid transport	biological process	GO:0006865	132	3	18204	49	SLC1A3,NTRK2,SLC1A2
5.392e-03	-5.22	Formin_Cappuccino_subfam	interpro domains	IPR001265	2	1	18521	50	FMN2
5.392e-03	-5.22	LRP1-like_beta_prop	interpro domains	IPR032485	2	1	18521	50	LRP1B
5.392e-03	-5.22	Distrobrevin	interpro domains	IPR017432	2	1	18521	50	DTNA
5.392e-03	-5.22	cGMP_dep_kinase	interpro domains	IPR002374	2	1	18521	50	PRKG1
5.392e-03	-5.22	Glyco_hydro_79	interpro domains	IPR005199	2	1	18521	50	HPSE2
5.392e-03	-5.22	Osteonectin_CS	interpro domains	IPR001999	2	1	18521	50	SPARCL1
5.392e-03	-5.22	Alpha_CARP_receptor-type	interpro domains	IPR041887	2	1	18521	50	PTPRZ1
5.392e-03	-5.22	STKc_cGK	interpro domains	IPR035014	2	1	18521	50	PRKG1
5.392e-03	-5.22	MSI_RRM2	interpro domains	IPR034126	2	1	18521	50	MSI2
5.394e-03	-5.22	left_upper_lobe	COSMIC cancer mutations	left_upper_lobe	558	6	16828	49	PRKG1,FBXL7,LRP1B,NTRK2,CTNND2,ADCY2
5.422e-03	-5.22	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-acute_lymphoblastic_leukaemia	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-acute_lymphoblastic_leukaemia	2081	13	16828	49	FGFR3,SOX5,PRKG1,BMPR1B,DTNA,LRP1B,NTRK2,PREX2,ADCY2,NFIA,PTPRZ1,ATP1A2,TNIK
5.440e-03	-5.21	monoatomic ion transmembrane transport	biological process	GO:0034220	804	7	18204	49	ATP1A2,SLC1A2,ITPR2,SLC1A3,GPM6A,ATP13A4,GABRB1
5.443e-03	-5.21	cyclic nucleotide metabolic process	biological process	GO:0009187	41	2	18204	49	RORA,ADCY2
5.476e-03	-5.21	Glycosaminoglycan metabolism	REACTOME pathways	R-HSA-1630316	124	3	10285	30	HPSE2,GPC5,CSGALNACT1
5.482e-03	-5.21	autonomic_ganglia-neuroblastoma	COSMIC cancer mutations	autonomic_ganglia-neuroblastoma	3970	20	16828	49	FMN2,NPAS3,FBXL7,PRKG1,PREX2,LRP1B,NTRK2,SLC1A2,FGFR3,GLIS3,PITPNC1,NFIA,ATP1A2,TNIK,GPM6A,PTPRZ1,PCDH9,COL5A3,CTNND2,ADCY2
5.493e-03	-5.20	PK_Tyr_Ser-Thr	pfam domains	PF07714	130	3	17795	49	NTRK2,FGFR3,BMPR1B
5.498e-03	-5.20	neuroblastoma	COSMIC cancer mutations	neuroblastoma	3971	20	16828	49	SLC1A2,FGFR3,GLIS3,FMN2,FBXL7,PRKG1,NPAS3,PREX2,NTRK2,LRP1B,COL5A3,CTNND2,ADCY2,PITPNC1,NFIA,ATP1A2,TNIK,PTPRZ1,GPM6A,PCDH9
5.500e-03	-5.20	Glyco_hydro_79n	pfam domains	PF03662	2	1	17795	49	HPSE2
5.500e-03	-5.20	DUF5050	pfam domains	PF16472	2	1	17795	49	LRP1B
5.505e-03	-5.20	acral_lentiginous	COSMIC cancer mutations	acral_lentiginous	745	7	16828	49	ATP13A4,FGFR3,CSGALNACT1,CDH20,PREX2,NRG3,LRP1B
5.545e-03	-5.19	neutral L-amino acid transmembrane transporter activity	molecular function	GO:0015175	42	2	18094	48	SLC1A3,SLC1A2
5.547e-03	-5.19	Ser-Thr/Tyr_kinase_cat_dom	interpro domains	IPR001245	133	3	18521	50	BMPR1B,FGFR3,NTRK2
5.565e-03	-5.19	regulation of canonical Wnt signaling pathway	biological process	GO:0060828	265	4	18204	49	APOE,GPC5,RBMS3,CTNND2
5.595e-03	-5.19	Retrograde endocannabinoid signaling	KEGG pathways	hsa04723	101	3	7161	26	GABRB1,ITPR2,ADCY2
5.595e-03	-5.19	Retrograde endocannabinoid signaling	KEGG pathways	ko04723	101	3	7161	26	ADCY2,ITPR2,GABRB1
5.706e-03	-5.17	regulation of amino acid transport	biological process	GO:0051955	42	2	18204	49	PRKG1,ATP1A2
5.706e-03	-5.17	triglyceride homeostasis	biological process	GO:0070328	42	2	18204	49	RORA,APOE
5.767e-03	-5.16	sarcolemma	cellular component	GO:0042383	142	3	19108	49	ATP1A2,PRKG1,DTNA
5.885e-03	-5.14	central_nervous_system-brain-glioma-oligodendroglioma_Grade_III	COSMIC cancer mutations	central_nervous_system-brain-glioma-oligodendroglioma_Grade_III	249	4	16828	49	MGAT4C,FGFR3,PTPRZ1,GLIS3
5.935e-03	-5.13	active monoatomic ion transmembrane transporter activity	molecular function	GO:0022853	274	4	18094	48	ATP13A4,SLC1A2,SLC1A3,ATP1A2
5.941e-03	-5.13	rhythmic process	biological process	GO:0048511	270	4	18204	49	NTRK2,BMPR1B,GABRB1,RORA
5.968e-03	-5.12	small_intestine	COSMIC cancer mutations	small_intestine	250	4	16828	49	MGAT4C,FGFR3,CSGALNACT1,TNIK
5.974e-03	-5.12	acylglycerol homeostasis	biological process	GO:0055090	43	2	18204	49	RORA,APOE
6.032e-03	-5.11	intracellular signal transduction	biological process	GO:0035556	1505	10	18204	49	FGFR3,FMN2,APOE,PREX2,ADCY2,NRG3,ATP1A2,TNIK,PRKG1,ITPR2
6.035e-03	-5.11	Ig-like_dom	interpro domains	IPR007110	432	5	18521	50	CADM1,LSAMP,NTRK2,NTM,FGFR3
6.141e-03	-5.09	metal ion transmembrane transporter activity	molecular function	GO:0046873	442	5	18094	48	GPM6A,ITPR2,ATP1A2,SLC1A3,SLC1A2
6.159e-03	-5.09	monoatomic cation transmembrane transporter activity	molecular function	GO:0008324	630	6	18094	48	ATP13A4,GPM6A,SLC1A2,ITPR2,ATP1A2,SLC1A3
6.257e-03	-5.07	lobular_carcinoma	COSMIC cancer mutations	lobular_carcinoma	763	7	16828	49	NTRK2,LRP1B,TNIK,BMPR1B,PRKG1,CDH20,FGFR3
6.257e-03	-5.07	breast-carcinoma-lobular_carcinoma	COSMIC cancer mutations	breast-carcinoma-lobular_carcinoma	763	7	16828	49	FGFR3,CDH20,PRKG1,BMPR1B,TNIK,LRP1B,NTRK2
6.338e-03	-5.06	Amyotrophic lateral sclerosis (ALS)	WikiPathways	WP2447	38	2	5310	17	SLC1A2,CST3
6.414e-03	-5.05	telencephalon development	biological process	GO:0021537	276	4	18204	49	SLC1A2,NTRK2,NRG3,ATP1A2
6.493e-03	-5.04	spleen	COSMIC cancer mutations	spleen	408	5	16828	49	TNIK,NTM,PTPRZ1,ADCY2,LRP1B
6.500e-03	-5.04	BDNF (brain derived neurotrophic factor)	protein interactions	627	47	2	19454	50	CPE,NTRK2
6.500e-03	-5.04	CNTN1 (contactin 1)	protein interactions	1272	47	2	19454	50	PTPRZ1,GPM6A
6.527e-03	-5.03	negative regulation of blood coagulation	biological process	GO:0030195	45	2	18204	49	PRKG1,APOE
6.588e-03	-5.02	monoatomic anion transmembrane transport	biological process	GO:0098656	142	3	18204	49	SLC1A2,SLC1A3,GABRB1
6.588e-03	-5.02	neuron migration	biological process	GO:0001764	142	3	18204	49	GPM6A,PRKG1,NTRK2
6.634e-03	-5.02	GSE1 (Gse1 coiled-coil protein)	protein interactions	23199	149	3	19454	50	SOX5,NFIA,TNIK
6.646e-03	-5.01	skin-trunk-malignant_melanoma	COSMIC cancer mutations	skin-trunk-malignant_melanoma	2647	15	16828	49	ATP13A4,MGAT4C,HPSE2,SOX5,PREX2,NRG3,LRP1B,CTNND2,SLC1A3,CDH20,NRXN1,ATP1A2,LSAMP,PTPRZ1,PCDH9
6.772e-03	-4.99	HTRA1 (HtrA serine peptidase 1)	protein interactions	5654	48	2	19454	50	MGAT4C,APOE
6.772e-03	-4.99	PATE1 (prostate and testis expressed 1)	protein interactions	160065	48	2	19454	50	CPE,LRP1B
6.812e-03	-4.99	receptor clustering	biological process	GO:0043113	46	2	18204	49	NRXN1,APOE
6.812e-03	-4.99	negative regulation of hemostasis	biological process	GO:1900047	46	2	18204	49	APOE,PRKG1
7.009e-03	-4.96	response to organic cyclic compound	biological process	GO:0014070	843	7	18204	49	ITPR2,SLC1A2,ATP1A2,ADCY2,GABRB1,RORA,SLC1A3
7.119e-03	-4.94	oligoastrocytoma_Grade_III	COSMIC cancer mutations	oligoastrocytoma_Grade_III	263	4	16828	49	PREX2,SOX5,SLC1A2,FGFR3
7.170e-03	-4.94	cell junction assembly	biological process	GO:0034329	285	4	18204	49	GPM6A,CDH20,NRG3,NRXN1
7.209e-03	-4.93	OSTEONECTIN_1	prosite domains	PS00612	2	1	12186	44	SPARCL1
7.209e-03	-4.93	OSTEONECTIN_2	prosite domains	PS00613	2	1	12186	44	SPARCL1
7.211e-03	-4.93	Retinoid metabolism and transport	REACTOME pathways	R-HSA-975634	44	2	10285	30	APOE,GPC5
7.399e-03	-4.91	regulation of amyloid-beta formation	biological process	GO:1902003	48	2	18204	49	APOE,NTRK2
7.404e-03	-4.91	large_intestine-adenoma	COSMIC cancer mutations	large_intestine-adenoma	266	4	16828	49	CDH20,SOX5,LRP1B,APOE
7.426e-03	-4.90	ATPASE_E1_E2	prosite domains	PS00154	36	2	12186	44	ATP13A4,ATP1A2
7.485e-03	-4.89	calcium channel regulator activity	molecular function	GO:0005246	49	2	18094	48	PRKG1,NRXN1
7.639e-03	-4.87	CGMPKINASE	prints domains	PR00104	2	1	5227	20	PRKG1
7.639e-03	-4.87	FORMIN	prints domains	PR00828	2	1	5227	20	FMN2
7.674e-03	-4.87	CATATPASE	prints domains	PR00119	35	2	5227	20	ATP13A4,ATP1A2
7.691e-03	-4.87	BCO1 (beta-carotene oxygenase 1)	protein interactions	53630	3	1	19454	50	ABLIM1
7.691e-03	-4.87	Spop (speckle-type BTB/POZ protein)	protein interactions	20747	3	1	19454	50	GLIS3
7.691e-03	-4.87	Plekhb1 (pleckstrin homology domain containing, family B (evectins) member 1)	protein interactions	27276	3	1	19454	50	BMPR1B
7.691e-03	-4.87	QRFPR (pyroglutamylated RFamide peptide receptor)	protein interactions	84109	3	1	19454	50	NTM
7.691e-03	-4.87	Atg16l1 (autophagy related 16 like 1)	protein interactions	77040	3	1	19454	50	BMPR1B
7.691e-03	-4.87	Usp45 (ubiquitin specific petidase 45)	protein interactions	77593	3	1	19454	50	BMPR1B
7.691e-03	-4.87	Fbxw5 (F-box and WD-40 domain protein 5)	protein interactions	30839	3	1	19454	50	BMPR1B
7.691e-03	-4.87	Stk35 (serine/threonine kinase 35)	protein interactions	67333	3	1	19454	50	BMPR1B
7.691e-03	-4.87	IL34 (interleukin 34)	protein interactions	146433	3	1	19454	50	PTPRZ1
7.691e-03	-4.87	Chn1 (chimerin 1)	protein interactions	108699	3	1	19454	50	BMPR1B
7.691e-03	-4.87	TULP1 (TUB like protein 1)	protein interactions	7287	3	1	19454	50	NRXN1
7.691e-03	-4.87	Smad6 (SMAD family member 6)	protein interactions	17130	3	1	19454	50	BMPR1B
7.691e-03	-4.87	Rap2a (RAS related protein 2a)	protein interactions	76108	3	1	19454	50	BMPR1B
7.700e-03	-4.87	negative regulation of coagulation	biological process	GO:0050819	49	2	18204	49	PRKG1,APOE
7.923e-03	-4.84	haematopoietic_and_lymphoid_tissue-abdomen-lymphoid_neoplasm-follicular_lymphoma	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue-abdomen-lymphoid_neoplasm-follicular_lymphoma	46	2	16828	49	ITPR2,RANBP3L
7.938e-03	-4.84	glucuronylgalactosylproteoglycan 4-beta-N-acetylgalactosaminyltransferase activity	molecular function	GO:0047237	3	1	18094	48	CSGALNACT1
7.938e-03	-4.84	cysteine transmembrane transporter activity	molecular function	GO:0033229	3	1	18094	48	SLC1A2
7.938e-03	-4.84	inositol 1,4,5-trisphosphate-gated calcium channel activity	molecular function	GO:0005220	3	1	18094	48	ITPR2
7.938e-03	-4.84	alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity	molecular function	GO:0008454	3	1	18094	48	MGAT4C
7.941e-03	-4.84	regulation of tube diameter	biological process	GO:0035296	152	3	18204	49	PRKG1,ATP1A2,APOE
7.941e-03	-4.84	blood vessel diameter maintenance	biological process	GO:0097746	152	3	18204	49	PRKG1,APOE,ATP1A2
8.007e-03	-4.83	vasodilation	biological process	GO:0042311	50	2	18204	49	PRKG1,APOE
8.054e-03	-4.82	susceptibility to natural killer cell mediated cytotoxicity	biological process	GO:0042271	3	1	18204	49	CADM1
8.054e-03	-4.82	neuroligin clustering involved in postsynaptic membrane assembly	biological process	GO:0097118	3	1	18204	49	NRXN1
8.054e-03	-4.82	cysteine transport	biological process	GO:0042883	3	1	18204	49	SLC1A2
8.054e-03	-4.82	positive regulation of low-density lipoprotein particle receptor catabolic process	biological process	GO:0032805	3	1	18204	49	APOE
8.054e-03	-4.82	meiotic chromosome movement towards spindle pole	biological process	GO:0016344	3	1	18204	49	FMN2
8.054e-03	-4.82	cysteine transmembrane transport	biological process	GO:1903712	3	1	18204	49	SLC1A2
8.054e-03	-4.82	formin-nucleated actin cable assembly	biological process	GO:0070649	3	1	18204	49	FMN2
8.054e-03	-4.82	UDP-N-acetylgalactosamine metabolic process	biological process	GO:0019276	3	1	18204	49	CSGALNACT1
8.054e-03	-4.82	very-low-density lipoprotein particle clearance	biological process	GO:0034447	3	1	18204	49	APOE
8.054e-03	-4.82	trans-synaptic signaling by BDNF, modulating synaptic transmission	biological process	GO:0099183	3	1	18204	49	NTRK2
8.054e-03	-4.82	regulation of calcium:sodium antiporter activity	biological process	GO:1903279	3	1	18204	49	ATP1A2
8.054e-03	-4.82	mammary placode formation	biological process	GO:0060596	3	1	18204	49	NRG3
8.054e-03	-4.82	formin-nucleated actin cable organization	biological process	GO:0110009	3	1	18204	49	FMN2
8.061e-03	-4.82	kidney-carcinoma-chromophobe_renal_cell_carcinoma	COSMIC cancer mutations	kidney-carcinoma-chromophobe_renal_cell_carcinoma	430	5	16828	49	NTRK2,TNIK,PRKG1,FGFR3,BMPR1B
8.061e-03	-4.82	chromophobe_renal_cell_carcinoma	COSMIC cancer mutations	chromophobe_renal_cell_carcinoma	430	5	16828	49	NTRK2,TNIK,BMPR1B,FGFR3,PRKG1
8.078e-03	-4.82	NTRK_LRRCT	interpro domains	IPR031635	3	1	18521	50	NTRK2
8.078e-03	-4.82	Neuregulin	interpro domains	IPR040180	3	1	18521	50	NRG3
8.078e-03	-4.82	InsP3_rcpt	interpro domains	IPR000493	3	1	18521	50	ITPR2
8.078e-03	-4.82	Myelin_PLP	interpro domains	IPR001614	3	1	18521	50	GPM6A
8.078e-03	-4.82	Myelin_PLP_CS	interpro domains	IPR018237	3	1	18521	50	GPM6A
8.078e-03	-4.82	GABAAb_rcpt	interpro domains	IPR002289	3	1	18521	50	GABRB1
8.078e-03	-4.82	NR_DBD_ROR	interpro domains	IPR044101	3	1	18521	50	RORA
8.078e-03	-4.82	NTRK	interpro domains	IPR020777	3	1	18521	50	NTRK2
8.078e-03	-4.82	ROR_rcpt	interpro domains	IPR003079	3	1	18521	50	RORA
8.085e-03	-4.82	regulation of tube size	biological process	GO:0035150	153	3	18204	49	PRKG1,ATP1A2,APOE
8.190e-03	-4.80	C11orf52 (chromosome 11 open reading frame 52)	protein interactions	91894	310	4	19454	50	FMN2,ABLIM1,DTNA,TNIK
8.196e-03	-4.80	PLC beta mediated events	REACTOME pathways	R-HSA-112043	47	2	10285	30	ITPR2,ADCY2
8.230e-03	-4.80	learning	biological process	GO:0007612	154	3	18204	49	NTRK2,NRXN1,ATP1A2
8.238e-03	-4.80	LRRCT_2	pfam domains	PF16920	3	1	17795	49	NTRK2
8.238e-03	-4.80	Myelin_PLP	pfam domains	PF01275	3	1	17795	49	GPM6A
8.267e-03	-4.80	carboxylic acid transport	biological process	GO:0046942	297	4	18204	49	APOE,SLC1A3,NTRK2,SLC1A2
8.295e-03	-4.79	endoplasmic reticulum lumen	cellular component	GO:0005788	312	4	19108	49	CST3,COL5A3,SPARCL1,APOE
8.320e-03	-4.79	neuromuscular process controlling balance	biological process	GO:0050885	51	2	18204	49	NRXN1,SLC1A3
8.358e-03	-4.78	neck	COSMIC cancer mutations	neck	1231	9	16828	49	ATP13A4,COL5A3,CTNND2,FGFR3,ADCY2,GPC5,PREX2,ATP1A2,LRP1B
8.363e-03	-4.78	organic acid transport	biological process	GO:0015849	298	4	18204	49	NTRK2,SLC1A2,APOE,SLC1A3
8.476e-03	-4.77	sodium ion transmembrane transporter activity	molecular function	GO:0015081	158	3	18094	48	SLC1A2,SLC1A3,ATP1A2
8.537e-03	-4.76	G-protein mediated events	REACTOME pathways	R-HSA-112040	48	2	10285	30	ADCY2,ITPR2
8.638e-03	-4.75	OCLN (occludin)	protein interactions	100506658	495	5	19454	50	TNIK,FMN2,NTRK2,ABLIM1,DTNA
8.675e-03	-4.75	positive regulation of synaptic transmission	biological process	GO:0050806	157	3	18204	49	NTRK2,NRXN1,SLC1A3
8.711e-03	-4.74	urinary_tract-bladder-papilloma	COSMIC cancer mutations	urinary_tract-bladder-papilloma	3	1	16828	49	FGFR3
8.711e-03	-4.74	skin-lentigo	COSMIC cancer mutations	skin-lentigo	3	1	16828	49	FGFR3
8.711e-03	-4.74	skin-leg-other-seborrhoeic_keratosis	COSMIC cancer mutations	skin-leg-other-seborrhoeic_keratosis	3	1	16828	49	FGFR3
8.711e-03	-4.74	lentigo	COSMIC cancer mutations	lentigo	3	1	16828	49	FGFR3
8.711e-03	-4.74	skin-face-lentigo	COSMIC cancer mutations	skin-face-lentigo	3	1	16828	49	FGFR3
8.711e-03	-4.74	skin-trunk-lentigo	COSMIC cancer mutations	skin-trunk-lentigo	3	1	16828	49	FGFR3
8.711e-03	-4.74	skin-trunk-other-seborrhoeic_keratosis	COSMIC cancer mutations	skin-trunk-other-seborrhoeic_keratosis	3	1	16828	49	FGFR3
8.711e-03	-4.74	skin-leg-lentigo	COSMIC cancer mutations	skin-leg-lentigo	3	1	16828	49	FGFR3
8.711e-03	-4.74	skin-hand-lentigo	COSMIC cancer mutations	skin-hand-lentigo	3	1	16828	49	FGFR3
8.711e-03	-4.74	skin-forearm-lentigo	COSMIC cancer mutations	skin-forearm-lentigo	3	1	16828	49	FGFR3
8.712e-03	-4.74	ATPase-coupled monoatomic cation transmembrane transporter activity	molecular function	GO:0019829	53	2	18094	48	ATP1A2,ATP13A4
8.761e-03	-4.74	postsynaptic density	cellular component	GO:0014069	317	4	19108	49	CADM1,NTRK2,CTNND2,TNIK
8.772e-03	-4.74	stomach-carcinoma	COSMIC cancer mutations	stomach-carcinoma	439	5	16828	49	TNIK,NTRK2,PRKG1,FGFR3,BMPR1B
8.836e-03	-4.73	skin-back-malignant_melanoma	COSMIC cancer mutations	skin-back-malignant_melanoma	280	4	16828	49	ATP1A2,TNIK,PREX2,LRP1B
8.962e-03	-4.71	neutral amino acid transport	biological process	GO:0015804	53	2	18204	49	SLC1A2,SLC1A3
8.962e-03	-4.71	regulation of platelet activation	biological process	GO:0010543	53	2	18204	49	APOE,PRKG1
8.962e-03	-4.71	regulation of chondrocyte differentiation	biological process	GO:0032330	53	2	18204	49	SOX5,BMPR1B
8.979e-03	-4.71	monoatomic anion transport	biological process	GO:0006820	159	3	18204	49	GABRB1,SLC1A3,SLC1A2
9.125e-03	-4.70	CSTL1 (cystatin like 1)	protein interactions	128817	56	2	19454	50	APOE,CPE
9.125e-03	-4.70	SEPTIN3 (septin 3)	protein interactions	55964	56	2	19454	50	PRKG1,GPM6A
9.215e-03	-4.69	Vascular smooth muscle contraction	KEGG pathways	ko04270	121	3	7161	26	PRKG1,ADCY2,ITPR2
9.215e-03	-4.69	Vascular smooth muscle contraction	KEGG pathways	hsa04270	121	3	7161	26	PRKG1,ITPR2,ADCY2
9.290e-03	-4.68	regulation of alcohol biosynthetic process	biological process	GO:1902930	54	2	18204	49	PRKG1,APOE
9.303e-03	-4.68	Prot_kinase_dom	interpro domains	IPR000719	480	5	18521	50	NTRK2,PRKG1,TNIK,FGFR3,BMPR1B
9.541e-03	-4.65	Ig-like_dom_sf	interpro domains	IPR036179	483	5	18521	50	CADM1,LSAMP,NTRK2,NTM,FGFR3
9.571e-03	-4.65	LYN (LYN proto-oncogene, Src family tyrosine kinase)	protein interactions	4067	713	6	19454	50	TNIK,SLC1A3,MSI2,DTNA,ABLIM1,FMN2
9.597e-03	-4.65	Chondroitin sulfate/dermatan sulfate metabolism	REACTOME pathways	R-HSA-1793185	51	2	10285	30	GPC5,CSGALNACT1
9.597e-03	-4.65	Neurotransmitter Release Cycle	REACTOME pathways	R-HSA-112310	51	2	10285	30	SLC1A2,SLC1A3
9.625e-03	-4.64	response to cocaine	biological process	GO:0042220	55	2	18204	49	SLC1A3,SLC1A2
9.625e-03	-4.64	regulation of amyloid precursor protein catabolic process	biological process	GO:1902991	55	2	18204	49	NTRK2,APOE
9.625e-03	-4.64	intermembrane lipid transfer	biological process	GO:0120009	55	2	18204	49	APOE,PITPNC1
9.630e-03	-4.64	CTNNA1 (catenin alpha 1)	protein interactions	1495	325	4	19454	50	DTNA,ABLIM1,NHSL1,TNIK
9.634e-03	-4.64	biliary_tract	COSMIC cancer mutations	biliary_tract	15309	49	16828	49	PRKG1,NPAS3,FBXL7,NHSL1,RBMS3,FGFR3,CST3,NKAIN3,GLIS3,APOE,NTM,TNIK,LSAMP,CTNND2,ABLIM1,FMN2,DTNA,NTRK2,CADM1,LRP1B,PREX2,HPSE2,MSI2,MGAT4C,GABRB1,GPC5,ZBTB20,CSGALNACT1,SLC1A2,CPE,PCDH9,PTPRZ1,GPM6A,ATP1A2,ADCY2,RANBP3L,CDH20,BMPR1B,RORA,NRG3,ATP13A4,SOX5,ITPR2,NFIA,PITPNC1,SPARCL1,COL5A3,NRXN1,SLC1A3
9.637e-03	-4.64	Platelet activation	KEGG pathways	hsa04611	123	3	7161	26	PRKG1,ITPR2,ADCY2
9.687e-03	-4.64	lipid transfer activity	molecular function	GO:0120013	56	2	18094	48	PITPNC1,APOE
9.751e-03	-4.63	dendritic spine	cellular component	GO:0043197	172	3	19108	49	GPM6A,NTRK2,ATP1A2
9.871e-03	-4.62	cell-cell junction	cellular component	GO:0005911	513	5	19108	49	PCDH9,CTNND2,CADM1,ATP1A2,CDH20
9.929e-03	-4.61	import across plasma membrane	biological process	GO:0098739	165	3	18204	49	SLC1A2,ATP1A2,SLC1A3
9.929e-03	-4.61	homophilic cell adhesion via plasma membrane adhesion molecules	biological process	GO:0007156	165	3	18204	49	CADM1,PCDH9,CDH20
9.962e-03	-4.61	thyroid-carcinoma-medullary_carcinoma	COSMIC cancer mutations	thyroid-carcinoma-medullary_carcinoma	290	4	16828	49	NRG3,PRKG1,FGFR3,SLC1A2
9.962e-03	-4.61	medullary_carcinoma	COSMIC cancer mutations	medullary_carcinoma	290	4	16828	49	NRG3,PRKG1,FGFR3,SLC1A2
1.006e-02	-4.60	neuron spine	cellular component	GO:0044309	174	3	19108	49	ATP1A2,NTRK2,GPM6A
1.022e-02	-4.58	intermediate-density lipoprotein particle	cellular component	GO:0034363	4	1	19108	49	APOE
1.022e-02	-4.58	collagen type V trimer	cellular component	GO:0005588	4	1	19108	49	COL5A3
1.023e-02	-4.58	ovary-carcinoma-mucinous_carcinoma	COSMIC cancer mutations	ovary-carcinoma-mucinous_carcinoma	456	5	16828	49	BMPR1B,FGFR3,PRKG1,TNIK,NTRK2
1.024e-02	-4.58	Ilkap (integrin-linked kinase-associated serine/threonine phosphatase 2C)	protein interactions	67444	4	1	19454	50	BMPR1B
1.024e-02	-4.58	Dnaja1 (DnaJ heat shock protein family (Hsp40) member A1)	protein interactions	15502	4	1	19454	50	GLIS3
1.024e-02	-4.58	IGKV@ (immunoglobulin kappa variable cluster)	protein interactions	3519	4	1	19454	50	LRP1B
1.024e-02	-4.58	Cdk14 (cyclin dependent kinase 14)	protein interactions	18647	4	1	19454	50	BMPR1B
1.024e-02	-4.58	Rhebl1 (Ras homolog enriched in brain like 1)	protein interactions	69159	4	1	19454	50	BMPR1B
1.024e-02	-4.58	Srgap1 (SLIT-ROBO Rho GTPase activating protein 1)	protein interactions	117600	4	1	19454	50	BMPR1B
1.024e-02	-4.58	CCDC126 (coiled-coil domain containing 126)	protein interactions	90693	4	1	19454	50	GPM6A
1.024e-02	-4.58	Nkiras1 (NFKB inhibitor interacting Ras-like protein 1)	protein interactions	69721	4	1	19454	50	BMPR1B
1.024e-02	-4.58	Nme2 (NME/NM23 nucleoside diphosphate kinase 2)	protein interactions	18103	4	1	19454	50	RORA
1.024e-02	-4.58	Naa20 (N(alpha)-acetyltransferase 20, NatB catalytic subunit)	protein interactions	67877	4	1	19454	50	BMPR1B
1.024e-02	-4.58	Arhgef6 (Rac/Cdc42 guanine nucleotide exchange factor 6)	protein interactions	73341	4	1	19454	50	BMPR1B
1.030e-02	-4.58	cellular response to growth factor stimulus	biological process	GO:0071363	494	5	18204	49	FGFR3,SOX5,BMPR1B,NFIA,NTRK2
1.031e-02	-4.57	visual behavior	biological process	GO:0007632	57	2	18204	49	ATP1A2,SLC1A2
1.034e-02	-4.57	Metabolism of fat-soluble vitamins	REACTOME pathways	R-HSA-6806667	53	2	10285	30	APOE,GPC5
1.034e-02	-4.57	NR3C1 (nuclear receptor subfamily 3 group C member 1)	protein interactions	2908	950	7	19454	50	SLC1A3,CADM1,ATP13A4,CTNND2,NFIA,ZBTB20,ADCY2
1.036e-02	-4.57	asymmetric synapse	cellular component	GO:0032279	333	4	19108	49	CADM1,CTNND2,NTRK2,TNIK
1.042e-02	-4.56	mucinous_carcinoma	COSMIC cancer mutations	mucinous_carcinoma	458	5	16828	49	BMPR1B,FGFR3,PRKG1,NTRK2,TNIK
1.042e-02	-4.56	SNTB1 (syntrophin beta 1)	protein interactions	6641	60	2	19454	50	DTNA,FGFR3
1.057e-02	-4.55	carbon-oxygen lyase activity, acting on phosphates	molecular function	GO:0016838	4	1	18094	48	ETNPPL
1.057e-02	-4.55	brain-derived neurotrophic factor binding	molecular function	GO:0048403	4	1	18094	48	NTRK2
1.057e-02	-4.55	very-low-density lipoprotein particle receptor binding	molecular function	GO:0070326	4	1	18094	48	APOE
1.061e-02	-4.55	adrenal_cortical_carcinoma	COSMIC cancer mutations	adrenal_cortical_carcinoma	2256	13	16828	49	NHSL1,FMN2,NTRK2,LRP1B,NRG3,SLC1A2,HPSE2,SOX5,PTPRZ1,ATP1A2,PCDH9,CTNND2,ZBTB20
1.071e-02	-4.54	Heparan sulfate/heparin (HS-GAG) metabolism	REACTOME pathways	R-HSA-1638091	54	2	10285	30	GPC5,HPSE2
1.072e-02	-4.54	regulation of collagen catabolic process	biological process	GO:0010710	4	1	18204	49	CST3
1.072e-02	-4.54	positive regulation of mesenchymal stem cell differentiation	biological process	GO:2000741	4	1	18204	49	SOX5
1.072e-02	-4.54	regulation of amino acid uptake involved in synaptic transmission	biological process	GO:0051941	4	1	18204	49	ATP1A2
1.072e-02	-4.54	brain-derived neurotrophic factor receptor signaling pathway	biological process	GO:0031547	4	1	18204	49	NTRK2
1.072e-02	-4.54	trans-synaptic signaling by BDNF	biological process	GO:0099191	4	1	18204	49	NTRK2
1.072e-02	-4.54	positive regulation of phospholipid efflux	biological process	GO:1902995	4	1	18204	49	APOE
1.072e-02	-4.54	ovarian cumulus expansion	biological process	GO:0001550	4	1	18204	49	BMPR1B
1.072e-02	-4.54	response to caloric restriction	biological process	GO:0061771	4	1	18204	49	APOE
1.072e-02	-4.54	response to glycoside	biological process	GO:1903416	4	1	18204	49	ATP1A2
1.072e-02	-4.54	protein localization to secretory granule	biological process	GO:0033366	4	1	18204	49	CPE
1.072e-02	-4.54	regulation of glutamate uptake involved in transmission of nerve impulse	biological process	GO:0051946	4	1	18204	49	ATP1A2
1.072e-02	-4.54	regulation of phospholipid efflux	biological process	GO:1902994	4	1	18204	49	APOE
1.072e-02	-4.54	NMDA glutamate receptor clustering	biological process	GO:0097114	4	1	18204	49	APOE
1.076e-02	-4.53	CTF/NFI_DNA-bd_N	interpro domains	IPR019548	4	1	18521	50	NFIA
1.076e-02	-4.53	Na/K-Atpase_Interacting	interpro domains	IPR008516	4	1	18521	50	NKAIN3
1.076e-02	-4.53	P5B-type_ATPase	interpro domains	IPR047821	4	1	18521	50	ATP13A4
1.076e-02	-4.53	Glyco_transf_54	interpro domains	IPR006759	4	1	18521	50	MGAT4C
1.076e-02	-4.53	FGF_rcpt_fam	interpro domains	IPR016248	4	1	18521	50	FGFR3
1.076e-02	-4.53	CTF/NFI	interpro domains	IPR000647	4	1	18521	50	NFIA
1.076e-02	-4.53	ApoA_E	interpro domains	IPR000074	4	1	18521	50	APOE
1.076e-02	-4.53	CTF/NFI_DNA-bd-dom	interpro domains	IPR020604	4	1	18521	50	NFIA
1.076e-02	-4.53	NHS-like	interpro domains	IPR024845	4	1	18521	50	NHSL1
1.076e-02	-4.53	CTF/NFI_DNA-bd_CS	interpro domains	IPR019739	4	1	18521	50	NFIA
1.076e-02	-4.53	AbLIM_anchor	interpro domains	IPR032402	4	1	18521	50	ABLIM1
1.076e-02	-4.53	P5A-ATPase_N	interpro domains	IPR047819	4	1	18521	50	ATP13A4
1.076e-02	-4.53	PRKG1 (protein kinase cGMP-dependent 1)	protein interactions	5592	61	2	19454	50	TNIK,PRKG1
1.079e-02	-4.53	MYELIN_PLP_2	prosite domains	PS01004	3	1	12186	44	GPM6A
1.079e-02	-4.53	MYELIN_PLP_1	prosite domains	PS00575	3	1	12186	44	GPM6A
1.090e-02	-4.52	testis-germ_cell_tumour-seminoma	COSMIC cancer mutations	testis-germ_cell_tumour-seminoma	648	6	16828	49	PREX2,TNIK,NTRK2,PRKG1,FGFR3,BMPR1B
1.093e-02	-4.52	adrenal_gland-adrenal_gland-adrenal_cortical_carcinoma-virilizing_syndrome_producing	COSMIC cancer mutations	adrenal_gland-adrenal_gland-adrenal_cortical_carcinoma-virilizing_syndrome_producing	298	4	16828	49	FMN2,CTNND2,LRP1B,ATP1A2
1.096e-02	-4.51	lung-carcinoma-large_cell_carcinoma	COSMIC cancer mutations	lung-carcinoma-large_cell_carcinoma	849	7	16828	49	PRKG1,BMPR1B,PTPRZ1,TNIK,NTRK2,FGFR3,GABRB1
1.096e-02	-4.51	large_cell_carcinoma	COSMIC cancer mutations	large_cell_carcinoma	849	7	16828	49	BMPR1B,FGFR3,PRKG1,GABRB1,NTRK2,TNIK,PTPRZ1
1.097e-02	-4.51	NfI_DNAbd_pre-N	pfam domains	PF10524	4	1	17795	49	NFIA
1.097e-02	-4.51	NHS	pfam domains	PF15273	4	1	17795	49	NHSL1
1.097e-02	-4.51	Glyco_transf_54	pfam domains	PF04666	4	1	17795	49	MGAT4C
1.097e-02	-4.51	AbLIM_anchor	pfam domains	PF16182	4	1	17795	49	ABLIM1
1.097e-02	-4.51	Apolipoprotein	pfam domains	PF01442	4	1	17795	49	APOE
1.097e-02	-4.51	P5-ATPase	pfam domains	PF12409	4	1	17795	49	ATP13A4
1.097e-02	-4.51	NKAIN	pfam domains	PF05640	4	1	17795	49	NKAIN3
1.097e-02	-4.51	CTF_NFI	pfam domains	PF00859	4	1	17795	49	NFIA
1.098e-02	-4.51	ovary-carcinoma-endometrioid_carcinoma	COSMIC cancer mutations	ovary-carcinoma-endometrioid_carcinoma	464	5	16828	49	BMPR1B,FGFR3,PRKG1,TNIK,NTRK2
1.098e-02	-4.51	primitive_neuroectodermal_tumour-medulloblastoma	COSMIC cancer mutations	primitive_neuroectodermal_tumour-medulloblastoma	15350	49	16828	49	NKAIN3,GLIS3,CST3,FGFR3,RBMS3,FBXL7,NPAS3,PRKG1,NHSL1,ABLIM1,CTNND2,NTM,TNIK,LSAMP,APOE,GABRB1,MGAT4C,MSI2,HPSE2,PREX2,LRP1B,DTNA,CADM1,NTRK2,FMN2,ZBTB20,GPC5,SLC1A2,CSGALNACT1,CDH20,ADCY2,RANBP3L,PTPRZ1,GPM6A,ATP1A2,PCDH9,CPE,SOX5,ATP13A4,NRG3,RORA,BMPR1B,SLC1A3,NRXN1,SPARCL1,COL5A3,NFIA,PITPNC1,ITPR2
1.106e-02	-4.50	chondroitin biosynthesis	BIOCYC pathways	META_PWY-6566	5	1	902	2	CSGALNACT1
1.107e-02	-4.50	inorganic molecular entity transmembrane transporter activity	molecular function	GO:0015318	714	6	18094	48	SLC1A2,GPM6A,ATP1A2,ITPR2,SLC1A3,GABRB1
1.113e-02	-4.50	PROTEIN_KINASE_ATP	prosite domains	PS00107	377	5	12186	44	NTRK2,BMPR1B,FGFR3,PRKG1,TNIK
1.113e-02	-4.50	cell migration	biological process	GO:0016477	921	7	18204	49	PRKG1,NRG3,CDH20,GPC5,NTRK2,FMN2,GPM6A
1.137e-02	-4.48	proteoglycan biosynthetic process	biological process	GO:0030166	60	2	18204	49	CSGALNACT1,BMPR1B
1.137e-02	-4.48	regulation of smooth muscle contraction	biological process	GO:0006940	60	2	18204	49	PRKG1,ATP1A2
1.137e-02	-4.48	transmission of nerve impulse	biological process	GO:0019226	60	2	18204	49	ATP1A2,NTRK2
1.138e-02	-4.48	PLP	smart domains	SM00002	3	1	9717	37	GPM6A
1.143e-02	-4.47	human chr4q34.2	chromosome location	human chr4q34.2	6	1	26134	50	GPM6A
1.143e-02	-4.47	human chr14q13.1	chromosome location	human chr14q13.1	6	1	26134	50	NPAS3
1.144e-02	-4.47	MYELINPLP	prints domains	PR00214	3	1	5227	20	GPM6A
1.144e-02	-4.47	RORNUCRECPTR	prints domains	PR01293	3	1	5227	20	RORA
1.144e-02	-4.47	NTKRECEPTOR	prints domains	PR01939	3	1	5227	20	NTRK2
1.144e-02	-4.47	GABAARBETA	prints domains	PR01160	3	1	5227	20	GABRB1
1.144e-02	-4.47	INSP3RECEPTR	prints domains	PR00779	3	1	5227	20	ITPR2
1.145e-02	-4.47	Signalling by NGF	REACTOME pathways	R-HSA-166520	477	5	10285	30	NTRK2,ITPR2,NRG3,FGFR3,ADCY2
1.148e-02	-4.47	adrenal_cortical_adenoma	COSMIC cancer mutations	adrenal_cortical_adenoma	161	3	16828	49	LRP1B,ADCY2,FMN2
1.148e-02	-4.47	regulation of lipid metabolic process	biological process	GO:0019216	327	4	18204	49	RORA,APOE,ZBTB20,PRKG1
1.149e-02	-4.47	GABA receptor activation	REACTOME pathways	R-HSA-977443	56	2	10285	30	ADCY2,GABRB1
1.149e-02	-4.47	Ion homeostasis	REACTOME pathways	R-HSA-5578775	56	2	10285	30	ITPR2,ATP1A2
1.153e-02	-4.46	circulatory system process	biological process	GO:0003013	508	5	18204	49	ATP1A2,SLC1A3,APOE,SLC1A2,PRKG1
1.156e-02	-4.46	oligodendroglioma_Grade_III	COSMIC cancer mutations	oligodendroglioma_Grade_III	303	4	16828	49	GLIS3,PTPRZ1,MGAT4C,FGFR3
1.160e-02	-4.46	urinary_tract-bladder-other-normal	COSMIC cancer mutations	urinary_tract-bladder-other-normal	4	1	16828	49	FGFR3
1.160e-02	-4.46	urinary_tract-bladder-papilloma-inverted	COSMIC cancer mutations	urinary_tract-bladder-papilloma-inverted	4	1	16828	49	FGFR3
1.160e-02	-4.46	skin-face-malignant_melanoma-superficial_spreading	COSMIC cancer mutations	skin-face-malignant_melanoma-superficial_spreading	4	1	16828	49	PREX2
1.160e-02	-4.46	inverted	COSMIC cancer mutations	inverted	4	1	16828	49	FGFR3
1.160e-02	-4.46	skin-benign_melanocytic_nevus-junctional	COSMIC cancer mutations	skin-benign_melanocytic_nevus-junctional	4	1	16828	49	FGFR3
1.160e-02	-4.46	skin-lower_leg-malignant_melanoma-nodular	COSMIC cancer mutations	skin-lower_leg-malignant_melanoma-nodular	4	1	16828	49	PREX2
1.165e-02	-4.45	Synaptic Vesicle Pathway	WikiPathways	WP2267	52	2	5310	17	ATP1A2,SLC1A3
1.178e-02	-4.44	transmembrane receptor protein tyrosine kinase activity	molecular function	GO:0004714	62	2	18094	48	NTRK2,FGFR3
1.179e-02	-4.44	LIPG (lipase G, endothelial type)	protein interactions	9388	64	2	19454	50	ETNPPL,FGFR3
1.179e-02	-4.44	EVA1C (eva-1 homolog C)	protein interactions	59271	64	2	19454	50	PCDH9,BMPR1B
1.184e-02	-4.44	upper_aerodigestive_tract-mouth-carcinoma	COSMIC cancer mutations	upper_aerodigestive_tract-mouth-carcinoma	6426	27	16828	49	FGFR3,SLC1A2,FBXL7,PRKG1,NPAS3,NHSL1,CTNND2,ABLIM1,ADCY2,CDH20,APOE,NTM,GPM6A,HPSE2,MGAT4C,GABRB1,SOX5,FMN2,RORA,LRP1B,NRG3,PREX2,COL5A3,ZBTB20,SLC1A3,GPC5,PITPNC1
1.196e-02	-4.43	regulation of small molecule metabolic process	biological process	GO:0062012	331	4	18204	49	APOE,RORA,PRKG1,ZBTB20
1.213e-02	-4.41	Transmembrane transport of small molecules	REACTOME pathways	R-HSA-382551	677	6	10285	30	ATP1A2,ADCY2,SLC1A3,SLC1A2,GABRB1,ATP13A4
1.229e-02	-4.40	Ion transport by P-type ATPases	REACTOME pathways	R-HSA-936837	58	2	10285	30	ATP1A2,ATP13A4
1.237e-02	-4.39	lipid homeostasis	biological process	GO:0055088	179	3	18204	49	APOE,RORA,ZBTB20
1.245e-02	-4.39	camera-type eye development	biological process	GO:0043010	335	4	18204	49	GPM6A,NFIA,BMPR1B,NTRK2
1.262e-02	-4.37	Ig-like_fold	interpro domains	IPR013783	721	6	18521	50	CADM1,LSAMP,NTM,NTRK2,PTPRZ1,FGFR3
1.279e-02	-4.36	PPP1R17 (protein phosphatase 1 regulatory subunit 17)	protein interactions	10842	5	1	19454	50	PRKG1
1.279e-02	-4.36	Wwp2 (WW domain containing E3 ubiquitin protein ligase 2)	protein interactions	66894	5	1	19454	50	GLIS3
1.279e-02	-4.36	TRH (thyrotropin releasing hormone)	protein interactions	7200	5	1	19454	50	CPE
1.279e-02	-4.36	Cdk4 (cyclin dependent kinase 4)	protein interactions	12567	5	1	19454	50	BMPR1B
1.279e-02	-4.36	Rab38 (RAB38, member RAS oncogene family)	protein interactions	72433	5	1	19454	50	BMPR1B
1.279e-02	-4.36	Rhobtb1 (Rho-related BTB domain containing 1)	protein interactions	69288	5	1	19454	50	BMPR1B
1.279e-02	-4.36	SYT13 (synaptotagmin 13)	protein interactions	57586	5	1	19454	50	NRXN1
1.279e-02	-4.36	Rhoj (ras homolog family member J)	protein interactions	80837	5	1	19454	50	BMPR1B
1.279e-02	-4.36	Rras2 (related RAS viral (r-ras) oncogene 2)	protein interactions	66922	5	1	19454	50	BMPR1B
1.279e-02	-4.36	Rab6b (RAB6B, member RAS oncogene family)	protein interactions	270192	5	1	19454	50	BMPR1B
1.281e-02	-4.36	cell population proliferation	biological process	GO:0008283	726	6	18204	49	NFIA,SOX5,HPSE2,CADM1,FGFR3,RORA
1.287e-02	-4.35	dendrite morphogenesis	biological process	GO:0048813	64	2	18204	49	CTNND2,PREX2
1.296e-02	-4.35	regulation of Wnt signaling pathway	biological process	GO:0030111	339	4	18204	49	RBMS3,APOE,GPC5,CTNND2
1.312e-02	-4.33	regulation of carbohydrate metabolic process	biological process	GO:0006109	183	3	18204	49	ZBTB20,PRKG1,RORA
1.313e-02	-4.33	Kinase-like_dom_sf	interpro domains	IPR011009	523	5	18521	50	NTRK2,FGFR3,PRKG1,TNIK,BMPR1B
1.313e-02	-4.33	central_nervous_system-medulla-primitive_neuroectodermal_tumour-medulloblastoma-large_cell	COSMIC cancer mutations	central_nervous_system-medulla-primitive_neuroectodermal_tumour-medulloblastoma-large_cell	14773	48	16828	49	ATP13A4,SOX5,BMPR1B,RORA,NRG3,SPARCL1,COL5A3,SLC1A3,NRXN1,NFIA,PITPNC1,ITPR2,SLC1A2,CSGALNACT1,CDH20,ADCY2,RANBP3L,PTPRZ1,GPM6A,ATP1A2,CPE,PCDH9,MSI2,MGAT4C,HPSE2,GABRB1,FMN2,PREX2,CADM1,DTNA,LRP1B,NTRK2,ZBTB20,GPC5,FGFR3,GLIS3,CST3,NPAS3,PRKG1,FBXL7,NHSL1,RBMS3,CTNND2,ABLIM1,APOE,NTM,TNIK,LSAMP
1.313e-02	-4.33	central_nervous_system-medulla-primitive_neuroectodermal_tumour-medulloblastoma-desmoplastic	COSMIC cancer mutations	central_nervous_system-medulla-primitive_neuroectodermal_tumour-medulloblastoma-desmoplastic	14773	48	16828	49	SPARCL1,COL5A3,NRXN1,SLC1A3,ITPR2,NFIA,PITPNC1,ATP13A4,SOX5,RORA,BMPR1B,NRG3,ADCY2,RANBP3L,CDH20,PCDH9,CPE,GPM6A,PTPRZ1,ATP1A2,SLC1A2,CSGALNACT1,ZBTB20,GPC5,HPSE2,MGAT4C,MSI2,GABRB1,FMN2,LRP1B,NTRK2,DTNA,CADM1,PREX2,CTNND2,ABLIM1,APOE,NTM,TNIK,LSAMP,FGFR3,CST3,GLIS3,PRKG1,NPAS3,FBXL7,NHSL1,RBMS3
1.313e-02	-4.33	central_nervous_system-medulla-primitive_neuroectodermal_tumour-medulloblastoma-classic	COSMIC cancer mutations	central_nervous_system-medulla-primitive_neuroectodermal_tumour-medulloblastoma-classic	14773	48	16828	49	CST3,GLIS3,FGFR3,RBMS3,PRKG1,FBXL7,NPAS3,NHSL1,ABLIM1,CTNND2,NTM,TNIK,LSAMP,APOE,GABRB1,HPSE2,MGAT4C,MSI2,LRP1B,DTNA,CADM1,NTRK2,PREX2,FMN2,ZBTB20,GPC5,SLC1A2,CSGALNACT1,ADCY2,RANBP3L,CDH20,PCDH9,CPE,PTPRZ1,GPM6A,ATP1A2,SOX5,ATP13A4,NRG3,RORA,BMPR1B,NRXN1,SLC1A3,SPARCL1,COL5A3,ITPR2,NFIA,PITPNC1
1.313e-02	-4.33	central_nervous_system-medulla-primitive_neuroectodermal_tumour-medulloblastoma	COSMIC cancer mutations	central_nervous_system-medulla-primitive_neuroectodermal_tumour-medulloblastoma	14773	48	16828	49	SOX5,ATP13A4,NRG3,RORA,BMPR1B,SLC1A3,NRXN1,COL5A3,SPARCL1,PITPNC1,NFIA,ITPR2,SLC1A2,CSGALNACT1,CDH20,RANBP3L,ADCY2,ATP1A2,GPM6A,PTPRZ1,CPE,PCDH9,GABRB1,MSI2,MGAT4C,HPSE2,PREX2,LRP1B,CADM1,NTRK2,DTNA,FMN2,ZBTB20,GPC5,GLIS3,CST3,FGFR3,RBMS3,NHSL1,PRKG1,NPAS3,FBXL7,ABLIM1,CTNND2,LSAMP,TNIK,NTM,APOE
1.314e-02	-4.33	response to growth factor	biological process	GO:0070848	525	5	18204	49	FGFR3,SOX5,NFIA,BMPR1B,NTRK2
1.317e-02	-4.33	classic	COSMIC cancer mutations	classic	14774	48	16828	49	ABLIM1,CTNND2,NTM,TNIK,LSAMP,APOE,CST3,GLIS3,FGFR3,RBMS3,NPAS3,PRKG1,FBXL7,NHSL1,ZBTB20,GPC5,GABRB1,HPSE2,MGAT4C,MSI2,DTNA,NTRK2,CADM1,LRP1B,PREX2,FMN2,ADCY2,RANBP3L,CDH20,CPE,PCDH9,PTPRZ1,GPM6A,ATP1A2,SLC1A2,CSGALNACT1,NRXN1,SLC1A3,SPARCL1,COL5A3,ITPR2,NFIA,PITPNC1,SOX5,ATP13A4,NRG3,BMPR1B,RORA
1.320e-02	-4.33	neurotrophin receptor activity	molecular function	GO:0005030	5	1	18094	48	NTRK2
1.320e-02	-4.33	neuroligin family protein binding	molecular function	GO:0097109	5	1	18094	48	NRXN1
1.320e-02	-4.33	transforming growth factor beta receptor activity, type I	molecular function	GO:0005025	5	1	18094	48	BMPR1B
1.320e-02	-4.33	fibroblast growth factor receptor activity	molecular function	GO:0005007	5	1	18094	48	FGFR3
1.321e-02	-4.33	non_small_cell_carcinoma	COSMIC cancer mutations	non_small_cell_carcinoma	5198	23	16828	49	SLC1A3,COL5A3,SPARCL1,PITPNC1,ITPR2,SOX5,ATP13A4,MSI2,PREX2,NTRK2,LRP1B,RORA,BMPR1B,ABLIM1,ADCY2,CTNND2,TNIK,LSAMP,PTPRZ1,FGFR3,NPAS3,FBXL7,PRKG1
1.321e-02	-4.33	lung-carcinoma-non_small_cell_carcinoma	COSMIC cancer mutations	lung-carcinoma-non_small_cell_carcinoma	5198	23	16828	49	PRKG1,NPAS3,FBXL7,FGFR3,PTPRZ1,TNIK,LSAMP,ABLIM1,ADCY2,CTNND2,LRP1B,NTRK2,PREX2,RORA,BMPR1B,SOX5,MSI2,ATP13A4,ITPR2,PITPNC1,SLC1A3,SPARCL1,COL5A3
1.325e-02	-4.32	positive regulation of synapse assembly	biological process	GO:0051965	65	2	18204	49	NRXN1,NTRK2
1.327e-02	-4.32	L-amino acid transmembrane transporter activity	molecular function	GO:0015179	66	2	18094	48	SLC1A2,SLC1A3
1.328e-02	-4.32	positive regulation of multicellular organismal process	biological process	GO:0051240	1691	10	18204	49	BMPR1B,ZBTB20,PTPRZ1,ATP1A2,SOX5,NRXN1,NTRK2,CADM1,RORA,APOE
1.332e-02	-4.32	testis-germ_cell_tumour-non_seminoma	COSMIC cancer mutations	testis-germ_cell_tumour-non_seminoma	487	5	16828	49	NTRK2,TNIK,FGFR3,PRKG1,BMPR1B
1.332e-02	-4.32	human chr8q13.2	chromosome location	human chr8q13.2	7	1	26134	50	PREX2
1.332e-02	-4.32	human chr13q21.32	chromosome location	human chr13q21.32	7	1	26134	50	PCDH9
1.332e-02	-4.32	medulla	COSMIC cancer mutations	medulla	14778	48	16828	49	GPC5,ZBTB20,PREX2,CADM1,LRP1B,DTNA,NTRK2,FMN2,GABRB1,MSI2,MGAT4C,HPSE2,TNIK,LSAMP,NTM,APOE,ABLIM1,CTNND2,RBMS3,NHSL1,PRKG1,NPAS3,FBXL7,GLIS3,CST3,FGFR3,PITPNC1,NFIA,ITPR2,SLC1A3,NRXN1,COL5A3,SPARCL1,NRG3,RORA,BMPR1B,SOX5,ATP13A4,ATP1A2,GPM6A,PTPRZ1,CPE,PCDH9,CDH20,RANBP3L,ADCY2,CSGALNACT1,SLC1A2
1.336e-02	-4.32	desmoplastic	COSMIC cancer mutations	desmoplastic	14779	48	16828	49	BMPR1B,RORA,NRG3,ATP13A4,SOX5,NFIA,PITPNC1,ITPR2,SPARCL1,COL5A3,SLC1A3,NRXN1,CSGALNACT1,SLC1A2,GPM6A,PTPRZ1,ATP1A2,PCDH9,CPE,CDH20,ADCY2,RANBP3L,FMN2,PREX2,DTNA,NTRK2,LRP1B,CADM1,MGAT4C,MSI2,HPSE2,GABRB1,GPC5,ZBTB20,NPAS3,PRKG1,FBXL7,NHSL1,RBMS3,FGFR3,GLIS3,CST3,APOE,NTM,TNIK,LSAMP,CTNND2,ABLIM1
1.339e-02	-4.31	large_intestine-caecum-carcinoma-adenocarcinoma	COSMIC cancer mutations	large_intestine-caecum-carcinoma-adenocarcinoma	14236	47	16828	49	FGFR3,CST3,GLIS3,NKAIN3,NHSL1,FBXL7,NPAS3,PRKG1,CTNND2,ABLIM1,APOE,LSAMP,TNIK,NTM,HPSE2,MGAT4C,GABRB1,FMN2,DTNA,LRP1B,CADM1,NTRK2,PREX2,ZBTB20,GPC5,SLC1A2,CSGALNACT1,RANBP3L,ADCY2,CDH20,PCDH9,CPE,ATP1A2,PTPRZ1,GPM6A,ATP13A4,SOX5,BMPR1B,RORA,NRG3,COL5A3,SPARCL1,NRXN1,SLC1A3,ITPR2,PITPNC1,NFIA
1.339e-02	-4.31	positive regulation of dendritic spine maintenance	biological process	GO:1902952	5	1	18204	49	APOE
1.339e-02	-4.31	positive regulation of amyloid fibril formation	biological process	GO:1905908	5	1	18204	49	APOE
1.339e-02	-4.31	synaptic signaling via neuropeptide	biological process	GO:0099538	5	1	18204	49	NTRK2
1.339e-02	-4.31	negative regulation of chondrocyte proliferation	biological process	GO:1902731	5	1	18204	49	BMPR1B
1.339e-02	-4.31	glutamate receptor clustering	biological process	GO:0097688	5	1	18204	49	APOE
1.339e-02	-4.31	chylomicron remnant clearance	biological process	GO:0034382	5	1	18204	49	APOE
1.339e-02	-4.31	negative regulation of glutamate secretion	biological process	GO:0014050	5	1	18204	49	PRKG1
1.339e-02	-4.31	gephyrin clustering involved in postsynaptic density assembly	biological process	GO:0097116	5	1	18204	49	NRXN1
1.339e-02	-4.31	AMPA glutamate receptor clustering	biological process	GO:0097113	5	1	18204	49	APOE
1.339e-02	-4.31	amygdala development	biological process	GO:0021764	5	1	18204	49	ATP1A2
1.339e-02	-4.31	polar body extrusion after meiotic divisions	biological process	GO:0040038	5	1	18204	49	FMN2
1.342e-02	-4.31	salivary_gland-carcinoma-adenoid_cystic_carcinoma	COSMIC cancer mutations	salivary_gland-carcinoma-adenoid_cystic_carcinoma	488	5	16828	49	GABRB1,PRKG1,RORA,MGAT4C,CTNND2
1.343e-02	-4.31	PI_transfer	interpro domains	IPR001666	5	1	18521	50	PITPNC1
1.343e-02	-4.31	Follistatin/Osteonectin_EGF	interpro domains	IPR015369	5	1	18521	50	SPARCL1
1.343e-02	-4.31	Protocadherin	interpro domains	IPR013585	5	1	18521	50	PCDH9
1.343e-02	-4.31	Aminotrans_3	interpro domains	IPR005814	5	1	18521	50	ETNPPL
1.343e-02	-4.31	P-type_TPase_V	interpro domains	IPR006544	5	1	18521	50	ATP13A4
1.343e-02	-4.31	Aminotrans_3_PPA_site	interpro domains	IPR049704	5	1	18521	50	ETNPPL
1.353e-02	-4.30	Ca2+ pathway	REACTOME pathways	R-HSA-4086398	61	2	10285	30	ITPR2,PRKG1
1.364e-02	-4.29	L-alpha-amino acid transmembrane transport	biological process	GO:1902475	66	2	18204	49	SLC1A2,SLC1A3
1.369e-02	-4.29	Protocadherin	pfam domains	PF08374	5	1	17795	49	PCDH9
1.369e-02	-4.29	FOLN	pfam domains	PF09289	5	1	17795	49	SPARCL1
1.369e-02	-4.29	Aminotran_3	pfam domains	PF00202	5	1	17795	49	ETNPPL
1.369e-02	-4.29	IP_trans	pfam domains	PF02121	5	1	17795	49	PITPNC1
1.382e-02	-4.28	caecum	COSMIC cancer mutations	caecum	14248	47	16828	49	PRKG1,NPAS3,FBXL7,NHSL1,FGFR3,NKAIN3,GLIS3,CST3,APOE,NTM,TNIK,LSAMP,CTNND2,ABLIM1,FMN2,PREX2,DTNA,CADM1,NTRK2,LRP1B,MGAT4C,HPSE2,GABRB1,GPC5,ZBTB20,CSGALNACT1,SLC1A2,PTPRZ1,GPM6A,ATP1A2,CPE,PCDH9,CDH20,ADCY2,RANBP3L,RORA,BMPR1B,NRG3,ATP13A4,SOX5,NFIA,PITPNC1,ITPR2,SPARCL1,COL5A3,SLC1A3,NRXN1
1.384e-02	-4.28	Sudden Infant Death Syndrome (SIDS) Susceptibility Pathways	WikiPathways	WP706	162	3	5310	17	SLC1A3,NTRK2,RORA
1.387e-02	-4.28	non_seminoma	COSMIC cancer mutations	non_seminoma	492	5	16828	49	BMPR1B,PRKG1,FGFR3,NTRK2,TNIK
1.403e-02	-4.27	bone-extraskeletal-Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour	COSMIC cancer mutations	bone-extraskeletal-Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour	891	7	16828	49	ABLIM1,PTPRZ1,ATP1A2,FGFR3,ITPR2,NPAS3,SPARCL1
1.404e-02	-4.27	virilizing_syndrome_producing	COSMIC cancer mutations	virilizing_syndrome_producing	321	4	16828	49	FMN2,CTNND2,LRP1B,ATP1A2
1.404e-02	-4.27	collagen binding	molecular function	GO:0005518	68	2	18094	48	COL5A3,SPARCL1
1.405e-02	-4.27	monoatomic ion transport	biological process	GO:0006811	964	7	18204	49	ITPR2,SLC1A2,GPM6A,ATP13A4,GABRB1,ATP1A2,SLC1A3
1.412e-02	-4.26	neuron to neuron synapse	cellular component	GO:0098984	365	4	19108	49	CADM1,CTNND2,NTRK2,TNIK
1.413e-02	-4.26	phosphorus metabolic process	biological process	GO:0006793	1707	10	18204	49	FGFR3,RORA,CSGALNACT1,ADCY2,NTRK2,TNIK,ATP1A2,PRKG1,BMPR1B,PTPRZ1
1.424e-02	-4.25	EGF	pfam domains	PF00008	66	2	17795	49	NRXN1,LRP1B
1.430e-02	-4.25	regulation of lipid biosynthetic process	biological process	GO:0046890	189	3	18204	49	APOE,PRKG1,ZBTB20
1.433e-02	-4.25	haematopoietic_and_lymphoid_tissue-spleen-lymphoid_neoplasm-marginal_zone_lymphoma	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue-spleen-lymphoid_neoplasm-marginal_zone_lymphoma	323	4	16828	49	PTPRZ1,NTM,LRP1B,ADCY2
1.437e-02	-4.24	CTF_NFI_2	prosite domains	PS51080	4	1	12186	44	NFIA
1.437e-02	-4.24	CTF_NFI_1	prosite domains	PS00349	4	1	12186	44	NFIA
1.437e-02	-4.24	CRYBG1 (crystallin beta-gamma domain containing 1)	protein interactions	202	71	2	19454	50	CSGALNACT1,SPARCL1
1.437e-02	-4.24	ANK2 (ankyrin 2)	protein interactions	287	71	2	19454	50	GPM6A,TNIK
1.448e-02	-4.24	skin-neck-other-nevus_sebaceous	COSMIC cancer mutations	skin-neck-other-nevus_sebaceous	5	1	16828	49	FGFR3
1.448e-02	-4.24	skin-upper_back-other-lichenoid_keratosis	COSMIC cancer mutations	skin-upper_back-other-lichenoid_keratosis	5	1	16828	49	FGFR3
1.448e-02	-4.24	skin-lower_leg-malignant_melanoma-superficial_spreading	COSMIC cancer mutations	skin-lower_leg-malignant_melanoma-superficial_spreading	5	1	16828	49	PREX2
1.448e-02	-4.24	skin-upper_leg-other-lichenoid_keratosis	COSMIC cancer mutations	skin-upper_leg-other-lichenoid_keratosis	5	1	16828	49	FGFR3
1.448e-02	-4.24	skin-breast-other-lichenoid_keratosis	COSMIC cancer mutations	skin-breast-other-lichenoid_keratosis	5	1	16828	49	FGFR3
1.448e-02	-4.24	skin-hip-other-seborrhoeic_keratosis	COSMIC cancer mutations	skin-hip-other-seborrhoeic_keratosis	5	1	16828	49	FGFR3
1.448e-02	-4.24	skin-chest-other-lichenoid_keratosis	COSMIC cancer mutations	skin-chest-other-lichenoid_keratosis	5	1	16828	49	FGFR3
1.448e-02	-4.24	skin-forearm-other-lichenoid_keratosis	COSMIC cancer mutations	skin-forearm-other-lichenoid_keratosis	5	1	16828	49	FGFR3
1.448e-02	-4.24	skin-lower_leg-other-lichenoid_keratosis	COSMIC cancer mutations	skin-lower_leg-other-lichenoid_keratosis	5	1	16828	49	FGFR3
1.448e-02	-4.24	skin-hand-other-lichenoid_keratosis	COSMIC cancer mutations	skin-hand-other-lichenoid_keratosis	5	1	16828	49	FGFR3
1.448e-02	-4.24	skin-lower_back-other-lichenoid_keratosis	COSMIC cancer mutations	skin-lower_back-other-lichenoid_keratosis	5	1	16828	49	FGFR3
1.448e-02	-4.24	skin-breast-other-nevus_sebaceous	COSMIC cancer mutations	skin-breast-other-nevus_sebaceous	5	1	16828	49	FGFR3
1.448e-02	-4.24	skin-forearm-other-seborrhoeic_keratosis	COSMIC cancer mutations	skin-forearm-other-seborrhoeic_keratosis	5	1	16828	49	FGFR3
1.448e-02	-4.24	skin-ear-other-nevus_sebaceous	COSMIC cancer mutations	skin-ear-other-nevus_sebaceous	5	1	16828	49	FGFR3
1.448e-02	-4.24	skin-shoulder-other-nevus_sebaceous	COSMIC cancer mutations	skin-shoulder-other-nevus_sebaceous	5	1	16828	49	FGFR3
1.448e-02	-4.24	monoclonal_gammopathy_of_undetermined_significance	COSMIC cancer mutations	monoclonal_gammopathy_of_undetermined_significance	5	1	16828	49	FGFR3
1.448e-02	-4.24	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-monoclonal_gammopathy_of_undetermined_significance	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-monoclonal_gammopathy_of_undetermined_significance	5	1	16828	49	FGFR3
1.448e-02	-4.24	skin-adnexal_tumour-syringocystadenoma_papilliferum	COSMIC cancer mutations	skin-adnexal_tumour-syringocystadenoma_papilliferum	5	1	16828	49	FGFR3
1.448e-02	-4.24	skin-flank-other-lichenoid_keratosis	COSMIC cancer mutations	skin-flank-other-lichenoid_keratosis	5	1	16828	49	FGFR3
1.448e-02	-4.24	skin-face-other-nevus_sebaceous	COSMIC cancer mutations	skin-face-other-nevus_sebaceous	5	1	16828	49	FGFR3
1.448e-02	-4.24	skin-face-other-lichenoid_keratosis	COSMIC cancer mutations	skin-face-other-lichenoid_keratosis	5	1	16828	49	FGFR3
1.448e-02	-4.24	syringocystadenoma_papilliferum	COSMIC cancer mutations	syringocystadenoma_papilliferum	5	1	16828	49	FGFR3
1.448e-02	-4.24	skin-upper_arm-other-lichenoid_keratosis	COSMIC cancer mutations	skin-upper_arm-other-lichenoid_keratosis	5	1	16828	49	FGFR3
1.448e-02	-4.24	skin-scalp-other-nevus_sebaceous	COSMIC cancer mutations	skin-scalp-other-nevus_sebaceous	5	1	16828	49	FGFR3
1.448e-02	-4.24	skin-other-lichenoid_keratosis	COSMIC cancer mutations	skin-other-lichenoid_keratosis	5	1	16828	49	FGFR3
1.448e-02	-4.24	skin-arm-other-seborrhoeic_keratosis	COSMIC cancer mutations	skin-arm-other-seborrhoeic_keratosis	5	1	16828	49	FGFR3
1.448e-02	-4.24	skin-lower_back-other-nevus_sebaceous	COSMIC cancer mutations	skin-lower_back-other-nevus_sebaceous	5	1	16828	49	FGFR3
1.448e-02	-4.24	skin-shoulder-other-lichenoid_keratosis	COSMIC cancer mutations	skin-shoulder-other-lichenoid_keratosis	5	1	16828	49	FGFR3
1.448e-02	-4.24	lichenoid_keratosis	COSMIC cancer mutations	lichenoid_keratosis	5	1	16828	49	FGFR3
1.448e-02	-4.24	skin-neck-other-lichenoid_keratosis	COSMIC cancer mutations	skin-neck-other-lichenoid_keratosis	5	1	16828	49	FGFR3
1.449e-02	-4.23	large_intestine-colon-carcinoma	COSMIC cancer mutations	large_intestine-colon-carcinoma	2612	14	16828	49	SLC1A3,NRXN1,ADCY2,COL5A3,PTPRZ1,PCDH9,CPE,ITPR2,GPC5,PREX2,NRG3,LRP1B,FMN2,RORA
1.450e-02	-4.23	NGF-independant TRKA activation	REACTOME pathways	R-HSA-187024	5	1	10285	30	NTRK2
1.456e-02	-4.23	Transferase(Phosphotransferase) domain 1	gene3d domains	1.10.510.10	490	5	14470	43	BMPR1B,TNIK,PRKG1,NTRK2,FGFR3
1.476e-02	-4.22	DPYSL3 (dihydropyrimidinase like 3)	protein interactions	1809	72	2	19454	50	TNIK,GPM6A
1.477e-02	-4.22	Apolipoprotein	gene3d domains	1.20.120.20	5	1	14470	43	APOE
1.485e-02	-4.21	regulation of blood coagulation	biological process	GO:0030193	69	2	18204	49	APOE,PRKG1
1.493e-02	-4.20	meninges-meningioma	COSMIC cancer mutations	meninges-meningioma	327	4	16828	49	FGFR3,ITPR2,FMN2,NFIA
1.501e-02	-4.20	extraskeletal	COSMIC cancer mutations	extraskeletal	903	7	16828	49	ABLIM1,ATP1A2,PTPRZ1,ITPR2,NPAS3,FGFR3,SPARCL1
1.501e-02	-4.20	lung-carcinoid-endocrine_tumour	COSMIC cancer mutations	lung-carcinoid-endocrine_tumour	502	5	16828	49	FGFR3,PRKG1,BMPR1B,TNIK,NTRK2
1.521e-02	-4.19	plasma membrane region	cellular component	GO:0098590	1278	8	19108	49	NRXN1,TNIK,SLC1A3,CADM1,GABRB1,GPM6A,SLC1A2,ATP1A2
1.526e-02	-4.18	ovulation cycle	biological process	GO:0042698	70	2	18204	49	BMPR1B,GABRB1
1.526e-02	-4.18	negative regulation of smooth muscle cell proliferation	biological process	GO:0048662	70	2	18204	49	APOE,PRKG1
1.527e-02	-4.18	Constitutive Signaling by Aberrant PI3K in Cancer	REACTOME pathways	R-HSA-2219530	65	2	10285	30	NRG3,FGFR3
1.529e-02	-4.18	multivesicular body, internal vesicle	cellular component	GO:0097487	6	1	19108	49	APOE
1.532e-02	-4.18	SOX11 (SRY-box transcription factor 11)	protein interactions	6664	6	1	19454	50	SOX5
1.532e-02	-4.18	GDF6 (growth differentiation factor 6)	protein interactions	392255	6	1	19454	50	BMPR1B
1.532e-02	-4.18	SLC12A5 (solute carrier family 12 member 5)	protein interactions	57468	6	1	19454	50	GPM6A
1.532e-02	-4.18	Fancl (Fanconi anemia, complementation group L)	protein interactions	67030	6	1	19454	50	BMPR1B
1.532e-02	-4.18	SYTL3 (synaptotagmin like 3)	protein interactions	94120	6	1	19454	50	NRXN1
1.532e-02	-4.18	SOX1 (SRY-box transcription factor 1)	protein interactions	6656	6	1	19454	50	SOX5
1.532e-02	-4.18	CYRIA (CYFIP related Rac1 interactor A)	protein interactions	81553	6	1	19454	50	GPM6A
1.532e-02	-4.18	LCAT (lecithin-cholesterol acyltransferase)	protein interactions	3931	6	1	19454	50	APOE
1.532e-02	-4.18	FXYD7 (FXYD domain containing ion transport regulator 7)	protein interactions	53822	6	1	19454	50	APOE
1.532e-02	-4.18	DRP2 (dystrophin related protein 2)	protein interactions	1821	6	1	19454	50	DTNA
1.532e-02	-4.18	FGF23 (fibroblast growth factor 23)	protein interactions	8074	6	1	19454	50	FGFR3
1.532e-02	-4.18	Map2k3 (mitogen-activated protein kinase kinase 3)	protein interactions	26397	6	1	19454	50	BMPR1B
1.532e-02	-4.18	Rhod (ras homolog family member D)	protein interactions	11854	6	1	19454	50	BMPR1B
1.532e-02	-4.18	Tiam2 (T cell lymphoma invasion and metastasis 2)	protein interactions	24001	6	1	19454	50	DTNA
1.532e-02	-4.18	ADCY1 (adenylate cyclase 1)	protein interactions	107	6	1	19454	50	ADCY2
1.532e-02	-4.18	Itch (itchy, E3 ubiquitin protein ligase)	protein interactions	16396	6	1	19454	50	GLIS3
1.532e-02	-4.18	FGF6 (fibroblast growth factor 6)	protein interactions	2251	6	1	19454	50	FGFR3
1.532e-02	-4.18	FGF18 (fibroblast growth factor 18)	protein interactions	8817	6	1	19454	50	FGFR3
1.547e-02	-4.17	cell-cell contact zone	cellular component	GO:0044291	74	2	19108	49	ATP1A2,PCDH9
1.549e-02	-4.17	seminoma	COSMIC cancer mutations	seminoma	700	6	16828	49	TNIK,PREX2,NTRK2,BMPR1B,PRKG1,FGFR3
1.555e-02	-4.16	marginal_zone_lymphoma	COSMIC cancer mutations	marginal_zone_lymphoma	331	4	16828	49	LRP1B,ADCY2,NTM,PTPRZ1
1.557e-02	-4.16	response to stimulus	biological process	GO:0050896	7803	29	18204	49	PREX2,NFIA,PRKG1,ZBTB20,DTNA,SPARCL1,APOE,NTRK2,NRG3,TNIK,CST3,CPE,ITPR2,SLC1A3,FGFR3,PITPNC1,GPM6A,RORA,FMN2,GABRB1,CADM1,ADCY2,SOX5,RBMS3,SLC1A2,ATP1A2,NRXN1,BMPR1B,CTNND2
1.567e-02	-4.16	regulation of hemostasis	biological process	GO:1900046	71	2	18204	49	APOE,PRKG1
1.573e-02	-4.15	lung-carcinoid-endocrine_tumour-atypical	COSMIC cancer mutations	lung-carcinoid-endocrine_tumour-atypical	508	5	16828	49	TNIK,NTRK2,FGFR3,PRKG1,BMPR1B
1.581e-02	-4.15	glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity	molecular function	GO:0047238	6	1	18094	48	CSGALNACT1
1.581e-02	-4.15	phosphatidylcholine-sterol O-acyltransferase activator activity	molecular function	GO:0060228	6	1	18094	48	APOE
1.581e-02	-4.15	steroid hormone binding	molecular function	GO:1990239	6	1	18094	48	ATP1A2
1.597e-02	-4.14	locomotory behavior	biological process	GO:0007626	197	3	18204	49	APOE,ATP1A2,PREX2
1.600e-02	-4.14	IG	smart domains	SM00409	394	5	9717	37	CADM1,NTRK2,FGFR3,NTM,LSAMP
1.604e-02	-4.13	vocal learning	biological process	GO:0042297	6	1	18204	49	NRXN1
1.604e-02	-4.13	cellular response to histamine	biological process	GO:0071420	6	1	18204	49	GABRB1
1.604e-02	-4.13	establishment of meiotic spindle localization	biological process	GO:0051295	6	1	18204	49	FMN2
1.604e-02	-4.13	mammary gland formation	biological process	GO:0060592	6	1	18204	49	NRG3
1.604e-02	-4.13	fused antrum stage	biological process	GO:0048165	6	1	18204	49	BMPR1B
1.604e-02	-4.13	imitative learning	biological process	GO:0098596	6	1	18204	49	NRXN1
1.604e-02	-4.13	ERBB4-ERBB4 signaling pathway	biological process	GO:0038138	6	1	18204	49	NRG3
1.604e-02	-4.13	triglyceride-rich lipoprotein particle clearance	biological process	GO:0071830	6	1	18204	49	APOE
1.604e-02	-4.13	relaxation of vascular associated smooth muscle	biological process	GO:0060087	6	1	18204	49	PRKG1
1.604e-02	-4.13	asymmetric neuroblast division	biological process	GO:0055059	6	1	18204	49	SOX5
1.604e-02	-4.13	regulation of low-density lipoprotein particle receptor catabolic process	biological process	GO:0032803	6	1	18204	49	APOE
1.604e-02	-4.13	negative regulation of extracellular matrix disassembly	biological process	GO:0010716	6	1	18204	49	CST3
1.604e-02	-4.13	postsynaptic density protein 95 clustering	biological process	GO:0097119	6	1	18204	49	NRXN1
1.604e-02	-4.13	gamma-aminobutyric acid biosynthetic process	biological process	GO:0009449	6	1	18204	49	SLC1A3
1.609e-02	-4.13	Glypican_CS	interpro domains	IPR019803	6	1	18521	50	GPC5
1.609e-02	-4.13	EF-hand_dom_typ2	interpro domains	IPR015154	6	1	18521	50	DTNA
1.609e-02	-4.13	Ins145_P3_rcpt	interpro domains	IPR014821	6	1	18521	50	ITPR2
1.609e-02	-4.13	GLI-like	interpro domains	IPR043359	6	1	18521	50	GLIS3
1.609e-02	-4.13	RIH_dom	interpro domains	IPR000699	6	1	18521	50	ITPR2
1.609e-02	-4.13	RyR/IP3R_RIH_dom_sf	interpro domains	IPR035910	6	1	18521	50	ITPR2
1.609e-02	-4.13	P-type_ATPase_IIC	interpro domains	IPR005775	6	1	18521	50	ATP1A2
1.609e-02	-4.13	RIH_assoc-dom	interpro domains	IPR013662	6	1	18521	50	ITPR2
1.609e-02	-4.13	EF-hand_dom_typ1	interpro domains	IPR015153	6	1	18521	50	DTNA
1.609e-02	-4.13	Glypican	interpro domains	IPR001863	6	1	18521	50	GPC5
1.609e-02	-4.13	Ryanodine_IP3_receptor	interpro domains	IPR015925	6	1	18521	50	ITPR2
1.609e-02	-4.13	Adcy_conserved_dom	interpro domains	IPR009398	6	1	18521	50	ADCY2
1.609e-02	-4.13	Syndecan/Neurexin_dom	interpro domains	IPR027789	6	1	18521	50	NRXN1
1.609e-02	-4.13	large_cell	COSMIC cancer mutations	large_cell	14845	48	16828	49	GABRB1,HPSE2,MSI2,MGAT4C,CADM1,DTNA,NTRK2,LRP1B,PREX2,FMN2,ZBTB20,GPC5,CST3,GLIS3,FGFR3,RBMS3,FBXL7,NPAS3,PRKG1,NHSL1,ABLIM1,CTNND2,NTM,TNIK,LSAMP,APOE,SOX5,ATP13A4,NRG3,RORA,BMPR1B,NRXN1,SLC1A3,SPARCL1,COL5A3,ITPR2,NFIA,PITPNC1,SLC1A2,CSGALNACT1,ADCY2,RANBP3L,CDH20,CPE,PCDH9,GPM6A,PTPRZ1,ATP1A2
1.616e-02	-4.13	Regulation of lipolysis in adipocytes	KEGG pathways	hsa04923	54	2	7161	26	ADCY2,PRKG1
1.628e-02	-4.12	haematopoietic_and_lymphoid_tissue-soft_tissue-lymphoid_neoplasm-diffuse_large_B_cell_lymphoma	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue-soft_tissue-lymphoid_neoplasm-diffuse_large_B_cell_lymphoma	67	2	16828	49	PCDH9,LRP1B
1.640e-02	-4.11	positive regulation of ERK1 and ERK2 cascade	biological process	GO:0070374	199	3	18204	49	NTRK2,APOE,FGFR3
1.641e-02	-4.11	Adcy_cons_dom	pfam domains	PF06327	6	1	17795	49	ADCY2
1.641e-02	-4.11	RYDR_ITPR	pfam domains	PF01365	6	1	17795	49	ITPR2
1.641e-02	-4.11	Ins145_P3_rec	pfam domains	PF08709	6	1	17795	49	ITPR2
1.641e-02	-4.11	RIH_assoc	pfam domains	PF08454	6	1	17795	49	ITPR2
1.641e-02	-4.11	EF-hand_2	pfam domains	PF09068	6	1	17795	49	DTNA
1.641e-02	-4.11	Syndecan	pfam domains	PF01034	6	1	17795	49	NRXN1
1.641e-02	-4.11	Glypican	pfam domains	PF01153	6	1	17795	49	GPC5
1.641e-02	-4.11	EF-hand_3	pfam domains	PF09069	6	1	17795	49	DTNA
1.652e-02	-4.10	regulation of cartilage development	biological process	GO:0061035	73	2	18204	49	BMPR1B,SOX5
1.652e-02	-4.10	peptide metabolic process	biological process	GO:0006518	73	2	18204	49	SLC1A2,CPE
1.652e-02	-4.10	negative regulation of wound healing	biological process	GO:0061045	73	2	18204	49	APOE,PRKG1
1.660e-02	-4.10	atypical	COSMIC cancer mutations	atypical	515	5	16828	49	TNIK,NTRK2,BMPR1B,FGFR3,PRKG1
1.668e-02	-4.09	ductolobular_carcinoma	COSMIC cancer mutations	ductolobular_carcinoma	1619	10	16828	49	RORA,FMN2,CPE,DTNA,PTPRZ1,PREX2,FGFR3,CTNND2,ABLIM1,CDH20
1.668e-02	-4.09	breast-carcinoma-ductolobular_carcinoma	COSMIC cancer mutations	breast-carcinoma-ductolobular_carcinoma	1619	10	16828	49	FGFR3,CTNND2,ABLIM1,CDH20,FMN2,RORA,CPE,DTNA,PTPRZ1,PREX2
1.673e-02	-4.09	axonogenesis	biological process	GO:0007409	366	4	18204	49	PTPRZ1,BMPR1B,PRKG1,NRXN1
1.680e-02	-4.09	embryonal	COSMIC cancer mutations	embryonal	2659	14	16828	49	GLIS3,FGFR3,LRP1B,PREX2,NPAS3,FMN2,RORA,ADCY2,SPARCL1,COL5A3,CTNND2,PTPRZ1,APOE,NFIA
1.680e-02	-4.09	soft_tissue-striated_muscle-rhabdomyosarcoma-embryonal	COSMIC cancer mutations	soft_tissue-striated_muscle-rhabdomyosarcoma-embryonal	2659	14	16828	49	GLIS3,FGFR3,PREX2,LRP1B,NPAS3,RORA,FMN2,ADCY2,SPARCL1,CTNND2,COL5A3,PTPRZ1,NFIA,APOE
1.695e-02	-4.08	regulation of coagulation	biological process	GO:0050818	74	2	18204	49	PRKG1,APOE
1.701e-02	-4.07	middle_lobe	COSMIC cancer mutations	middle_lobe	1382	9	16828	49	ATP1A2,LRP1B,CPE,PCDH9,ITPR2,ATP13A4,CTNND2,HPSE2,FGFR3
1.705e-02	-4.07	HAD_sf	interpro domains	IPR023214	74	2	18521	50	ATP1A2,ATP13A4
1.709e-02	-4.07	human chr4q22.3	chromosome location	human chr4q22.3	9	1	26134	50	BMPR1B
1.717e-02	-4.06	ATP2B3 (ATPase plasma membrane Ca2+ transporting 3)	protein interactions	492	78	2	19454	50	CSGALNACT1,GPM6A
1.717e-02	-4.06	IFIT3 (interferon induced protein with tetratricopeptide repeats 3)	protein interactions	3437	78	2	19454	50	ATP1A2,APOE
1.717e-02	-4.06	Nedd4 (NEDD4 E3 ubiquitin protein ligase)	protein interactions	25489	78	2	19454	50	NTRK2,BMPR1B
1.717e-02	-4.06	ANKRD40 (ankyrin repeat domain 40)	protein interactions	91369	78	2	19454	50	SOX5,MSI2
1.735e-02	-4.05	collecting_duct_carcinoma	COSMIC cancer mutations	collecting_duct_carcinoma	6	1	16828	49	FGFR3
1.735e-02	-4.05	skin-in_situ_epithelial_neoplasm-actinic_keratosis	COSMIC cancer mutations	skin-in_situ_epithelial_neoplasm-actinic_keratosis	6	1	16828	49	FGFR3
1.735e-02	-4.05	skin-abdomen-other-seborrhoeic_keratosis	COSMIC cancer mutations	skin-abdomen-other-seborrhoeic_keratosis	6	1	16828	49	FGFR3
1.735e-02	-4.05	skin-head_neck-epidermal_nevus	COSMIC cancer mutations	skin-head_neck-epidermal_nevus	6	1	16828	49	FGFR3
1.735e-02	-4.05	skin-head_neck-malignant_melanoma	COSMIC cancer mutations	skin-head_neck-malignant_melanoma	6	1	16828	49	PREX2
1.735e-02	-4.05	autonomic_ganglia-paraganglioma-benign	COSMIC cancer mutations	autonomic_ganglia-paraganglioma-benign	6	1	16828	49	NHSL1
1.735e-02	-4.05	skin-upper_leg-other-seborrhoeic_keratosis	COSMIC cancer mutations	skin-upper_leg-other-seborrhoeic_keratosis	6	1	16828	49	FGFR3
1.735e-02	-4.05	skin-in_situ_epithelial_neoplasm-Bowen_disease	COSMIC cancer mutations	skin-in_situ_epithelial_neoplasm-Bowen_disease	6	1	16828	49	FGFR3
1.735e-02	-4.05	skin-back-other-seborrhoeic_keratosis	COSMIC cancer mutations	skin-back-other-seborrhoeic_keratosis	6	1	16828	49	FGFR3
1.735e-02	-4.05	skin-face-other-seborrhoeic_keratosis	COSMIC cancer mutations	skin-face-other-seborrhoeic_keratosis	6	1	16828	49	FGFR3
1.735e-02	-4.05	lentiginous_nevus	COSMIC cancer mutations	lentiginous_nevus	6	1	16828	49	FGFR3
1.735e-02	-4.05	skin-flank-other-seborrhoeic_keratosis	COSMIC cancer mutations	skin-flank-other-seborrhoeic_keratosis	6	1	16828	49	FGFR3
1.735e-02	-4.05	skin-lower_back-other-seborrhoeic_keratosis	COSMIC cancer mutations	skin-lower_back-other-seborrhoeic_keratosis	6	1	16828	49	FGFR3
1.735e-02	-4.05	skin-trunk-epidermal_nevus	COSMIC cancer mutations	skin-trunk-epidermal_nevus	6	1	16828	49	FGFR3
1.735e-02	-4.05	skin-forearm-malignant_melanoma-superficial_spreading	COSMIC cancer mutations	skin-forearm-malignant_melanoma-superficial_spreading	6	1	16828	49	PREX2
1.735e-02	-4.05	skin-benign_melanocytic_nevus-lentiginous_nevus	COSMIC cancer mutations	skin-benign_melanocytic_nevus-lentiginous_nevus	6	1	16828	49	FGFR3
1.735e-02	-4.05	kidney-carcinoma-collecting_duct_carcinoma	COSMIC cancer mutations	kidney-carcinoma-collecting_duct_carcinoma	6	1	16828	49	FGFR3
1.735e-02	-4.05	skin-epidermal_nevus	COSMIC cancer mutations	skin-epidermal_nevus	6	1	16828	49	FGFR3
1.735e-02	-4.05	skin-adnexal_tumour-trichoblastoma	COSMIC cancer mutations	skin-adnexal_tumour-trichoblastoma	6	1	16828	49	FGFR3
1.735e-02	-4.05	skin-arm-epidermal_nevus	COSMIC cancer mutations	skin-arm-epidermal_nevus	6	1	16828	49	FGFR3
1.735e-02	-4.05	skin-lower_leg-epidermal_nevus	COSMIC cancer mutations	skin-lower_leg-epidermal_nevus	6	1	16828	49	FGFR3
1.738e-02	-4.05	Activation of TRKA receptors	REACTOME pathways	R-HSA-187015	6	1	10285	30	NTRK2
1.751e-02	-4.05	presynaptic active zone	cellular component	GO:0048786	79	2	19108	49	GPM6A,GABRB1
1.761e-02	-4.04	NCK1 (NCK adaptor protein 1)	protein interactions	4690	214	3	19454	50	NTRK2,NHSL1,TNIK
1.767e-02	-4.04	mannosyl-glycoprotein N-acetylglucosaminyltransferases	BIOCYC pathways	META_PWY-7426	8	1	902	2	MGAT4C
1.769e-02	-4.03	bone-tibia-chondrosarcoma	COSMIC cancer mutations	bone-tibia-chondrosarcoma	70	2	16828	49	CPE,RANBP3L
1.770e-02	-4.03	Single helix bin	gene3d domains	1.20.5.490	6	1	14470	43	PRKG1
1.770e-02	-4.03	IP3 receptor type 1 binding core, RIH domain	gene3d domains	1.25.10.30	6	1	14470	43	ITPR2
1.783e-02	-4.03	Endochondral Ossification	WikiPathways	WP474	65	2	5310	17	SOX5,FGFR3
1.785e-02	-4.03	nitrogen compound transport	biological process	GO:0071705	1507	9	18204	49	APOE,ATP13A4,FMN2,RANBP3L,SLC1A3,LRP1B,NTRK2,CPE,SLC1A2
1.786e-02	-4.03	Fbxo3 (F-box protein 3)	protein interactions	57443	7	1	19454	50	BMPR1B
1.786e-02	-4.03	Smurf1 (SMAD specific E3 ubiquitin protein ligase 1)	protein interactions	75788	7	1	19454	50	GLIS3
1.786e-02	-4.03	RGMB (repulsive guidance molecule BMP co-receptor b)	protein interactions	285704	7	1	19454	50	BMPR1B
1.786e-02	-4.03	SLC16A5 (solute carrier family 16 member 5)	protein interactions	9121	7	1	19454	50	PTPRZ1
1.786e-02	-4.03	Uhmk1 (U2AF homology motif (UHM) kinase 1)	protein interactions	16589	7	1	19454	50	BMPR1B
1.786e-02	-4.03	ABCC12 (ATP binding cassette subfamily C member 12)	protein interactions	94160	7	1	19454	50	NPAS3
1.786e-02	-4.03	FGF5 (fibroblast growth factor 5)	protein interactions	2250	7	1	19454	50	FGFR3
1.786e-02	-4.03	Smad7 (SMAD family member 7)	protein interactions	17131	7	1	19454	50	BMPR1B
1.786e-02	-4.03	SASH3 (SAM and SH3 domain containing 3)	protein interactions	54440	7	1	19454	50	BMPR1B
1.786e-02	-4.03	ZBTB45 (zinc finger and BTB domain containing 45)	protein interactions	84878	7	1	19454	50	ZBTB20
1.793e-02	-4.02	AA_TRANSFER_CLASS_3	prosite domains	PS00600	5	1	12186	44	ETNPPL
1.795e-02	-4.02	protein kinase activity	molecular function	GO:0004672	577	5	18094	48	NTRK2,BMPR1B,PRKG1,TNIK,FGFR3
1.801e-02	-4.02	MAP2 (microtubule associated protein 2)	protein interactions	4133	80	2	19454	50	GPM6A,APOE
1.815e-02	-4.01	Corticotropin Activation of Cortisol Production	SMPDB pathways	SMP0000310	5	1	1369	5	ADCY2
1.821e-02	-4.01	SMAD binding	molecular function	GO:0046332	78	2	18094	48	BMPR1B,RANBP3L
1.826e-02	-4.00	GFAP (glial fibrillary acidic protein)	protein interactions	2670	217	3	19454	50	ABLIM1,RORA,NKAIN3
1.827e-02	-4.00	neural retina development	biological process	GO:0003407	77	2	18204	49	NTRK2,GPM6A
1.827e-02	-4.00	regulation of organic acid transport	biological process	GO:0032890	77	2	18204	49	PRKG1,ATP1A2
1.827e-02	-4.00	regulation of synaptic transmission, glutamatergic	biological process	GO:0051966	77	2	18204	49	NRXN1,ATP1A2
1.827e-02	-4.00	BMP signaling pathway	biological process	GO:0030509	77	2	18204	49	NFIA,BMPR1B
1.829e-02	-4.00	cellular process	biological process	GO:0009987	14996	46	18204	49	PRKG1,ZBTB20,COL5A3,DTNA,APOE,HPSE2,CST3,TNIK,CPE,ITPR2,FGFR3,GLIS3,FMN2,NHSL1,ADCY2,MGAT4C,MSI2,FBXL7,RANBP3L,NTM,NRXN1,LSAMP,PREX2,LRP1B,CDH20,NFIA,PTPRZ1,SPARCL1,NTRK2,NRG3,PCDH9,GPC5,SLC1A3,PITPNC1,GPM6A,CSGALNACT1,GABRB1,RORA,ATP13A4,CADM1,SOX5,ABLIM1,SLC1A2,ATP1A2,BMPR1B,CTNND2
1.830e-02	-4.00	Downstream signal transduction	REACTOME pathways	R-HSA-186763	352	4	10285	30	NRG3,ITPR2,ADCY2,FGFR3
1.843e-02	-3.99	P-type sodium:potassium-exchanging transporter activity	molecular function	GO:0005391	7	1	18094	48	ATP1A2
1.843e-02	-3.99	mitogen-activated protein kinase p38 binding	molecular function	GO:0048273	7	1	18094	48	PRKG1
1.843e-02	-3.99	phosphatidic acid transfer activity	molecular function	GO:1990050	7	1	18094	48	PITPNC1
1.843e-02	-3.99	P-type sodium transporter activity	molecular function	GO:0008554	7	1	18094	48	ATP1A2
1.865e-02	-3.98	adrenal_gland-adrenal_gland-adrenal_cortical_adenoma-cortisol_producing	COSMIC cancer mutations	adrenal_gland-adrenal_gland-adrenal_cortical_adenoma-cortisol_producing	72	2	16828	49	FMN2,LRP1B
1.865e-02	-3.98	cortisol_producing	COSMIC cancer mutations	cortisol_producing	72	2	16828	49	LRP1B,FMN2
1.869e-02	-3.98	glial cell fate specification	biological process	GO:0021780	7	1	18204	49	NFIA
1.869e-02	-3.98	regulation of oligodendrocyte progenitor proliferation	biological process	GO:0070445	7	1	18204	49	PTPRZ1
1.869e-02	-3.98	regulation of testosterone biosynthetic process	biological process	GO:2000224	7	1	18204	49	PRKG1
1.869e-02	-3.98	parallel actin filament bundle assembly	biological process	GO:0030046	7	1	18204	49	FMN2
1.869e-02	-3.98	high-density lipoprotein particle clearance	biological process	GO:0034384	7	1	18204	49	APOE
1.869e-02	-3.98	relaxation of smooth muscle	biological process	GO:0044557	7	1	18204	49	PRKG1
1.869e-02	-3.98	interneuron migration from the subpallium to the cortex	biological process	GO:0021830	7	1	18204	49	NRG3
1.869e-02	-3.98	positive regulation of receptor catabolic process	biological process	GO:2000646	7	1	18204	49	APOE
1.869e-02	-3.98	chromosome movement towards spindle pole	biological process	GO:0051305	7	1	18204	49	FMN2
1.869e-02	-3.98	very-low-density lipoprotein particle remodeling	biological process	GO:0034372	7	1	18204	49	APOE
1.869e-02	-3.98	observational learning	biological process	GO:0098597	7	1	18204	49	NRXN1
1.873e-02	-3.98	IG_LIKE	prosite domains	PS50835	430	5	12186	44	FGFR3,NTM,CADM1,LSAMP,NTRK2
1.875e-02	-3.98	Hud_Sxl_RNA	interpro domains	IPR002343	7	1	18521	50	RBMS3
1.875e-02	-3.98	GS_dom	interpro domains	IPR003605	7	1	18521	50	BMPR1B
1.875e-02	-3.98	SPARC/Testican_Ca-bd-dom	interpro domains	IPR019577	7	1	18521	50	SPARCL1
1.875e-02	-3.98	Plakophilin/d_Catenin	interpro domains	IPR028435	7	1	18521	50	CTNND2
1.882e-02	-3.97	HAD-like_sf	interpro domains	IPR036412	78	2	18521	50	ATP13A4,ATP1A2
1.886e-02	-3.97	GSC (goosecoid homeobox)	protein interactions	145258	82	2	19454	50	NFIA,SOX5
1.886e-02	-3.97	TNNT1 (troponin T1, slow skeletal type)	protein interactions	7138	82	2	19454	50	BMPR1B,PRKG1
1.889e-02	-3.97	haematopoietic_and_lymphoid_tissue	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue	14368	47	16828	49	GABRB1,HPSE2,MGAT4C,MSI2,NTRK2,LRP1B,DTNA,CADM1,PREX2,FMN2,ZBTB20,GPC5,GLIS3,NKAIN3,FGFR3,RBMS3,NHSL1,NPAS3,PRKG1,FBXL7,ABLIM1,CTNND2,LSAMP,TNIK,NTM,SOX5,ATP13A4,NRG3,BMPR1B,RORA,NRXN1,SLC1A3,COL5A3,SPARCL1,ITPR2,PITPNC1,NFIA,SLC1A2,CSGALNACT1,RANBP3L,ADCY2,CDH20,CPE,PCDH9,ATP1A2,PTPRZ1,GPM6A
1.896e-02	-3.97	Immunoglobulins	gene3d domains	2.60.40.10	721	6	14470	43	NTM,NTRK2,CADM1,PTPRZ1,LSAMP,FGFR3
1.897e-02	-3.96	human chr12p11.23	chromosome location	human chr12p11.23	10	1	26134	50	ITPR2
1.897e-02	-3.96	human chr9p24.2	chromosome location	human chr9p24.2	10	1	26134	50	GLIS3
1.899e-02	-3.96	PITRANSFER	prints domains	PR00391	5	1	5227	20	PITPNC1
1.900e-02	-3.96	DAP12 signaling	REACTOME pathways	R-HSA-2424491	356	4	10285	30	ADCY2,FGFR3,NRG3,ITPR2
1.902e-02	-3.96	testis	COSMIC cancer mutations	testis	733	6	16828	49	BMPR1B,PRKG1,NTRK2,TNIK,PREX2,FGFR3
1.909e-02	-3.96	eye development	biological process	GO:0001654	381	4	18204	49	GPM6A,NTRK2,BMPR1B,NFIA
1.909e-02	-3.96	solute:sodium symporter activity	molecular function	GO:0015370	80	2	18094	48	SLC1A3,SLC1A2
1.911e-02	-3.96	synaptic membrane	cellular component	GO:0097060	400	4	19108	49	NRXN1,GABRB1,GPM6A,SLC1A2
1.912e-02	-3.96	SPARC_Ca_bdg	pfam domains	PF10591	7	1	17795	49	SPARCL1
1.912e-02	-3.96	TGF_beta_GS	pfam domains	PF08515	7	1	17795	49	BMPR1B
1.930e-02	-3.95	DNM3 (dynamin 3)	protein interactions	26052	83	2	19454	50	GPM6A,FGFR3
1.930e-02	-3.95	SYT1 (synaptotagmin 1)	protein interactions	6857	83	2	19454	50	NRXN1,GPM6A
1.939e-02	-3.94	PSEN1 (presenilin 1)	protein interactions	5663	222	3	19454	50	DTNA,APOE,CTNND2
1.943e-02	-3.94	stomach-carcinoma-mixed_intestinal_and_diffuse_adenocarcinoma-unclassifiable	COSMIC cancer mutations	stomach-carcinoma-mixed_intestinal_and_diffuse_adenocarcinoma-unclassifiable	951	7	16828	49	LRP1B,PREX2,GPC5,ITPR2,FMN2,SLC1A2,ATP13A4
1.943e-02	-3.94	mixed_intestinal_and_diffuse_adenocarcinoma-unclassifiable	COSMIC cancer mutations	mixed_intestinal_and_diffuse_adenocarcinoma-unclassifiable	951	7	16828	49	ITPR2,GPC5,FMN2,LRP1B,PREX2,SLC1A2,ATP13A4
1.944e-02	-3.94	inorganic cation transmembrane transporter activity	molecular function	GO:0022890	589	5	18094	48	GPM6A,ITPR2,ATP1A2,SLC1A3,SLC1A2
1.955e-02	-3.93	intracellular chemical homeostasis	biological process	GO:0055082	581	5	18204	49	ZBTB20,ATP1A2,SLC1A3,ATP13A4,APOE
1.962e-02	-3.93	skin-nipple-malignant_melanoma	COSMIC cancer mutations	skin-nipple-malignant_melanoma	197	3	16828	49	LRP1B,FMN2,BMPR1B
1.962e-02	-3.93	nipple	COSMIC cancer mutations	nipple	197	3	16828	49	LRP1B,BMPR1B,FMN2
1.972e-02	-3.93	Long-term depression	KEGG pathways	ko04730	60	2	7161	26	PRKG1,ITPR2
1.972e-02	-3.93	Long-term depression	KEGG pathways	hsa04730	60	2	7161	26	ITPR2,PRKG1
1.974e-02	-3.93	Tyr_kinase_cat_dom	interpro domains	IPR020635	80	2	18521	50	NTRK2,FGFR3
1.976e-02	-3.92	visual system development	biological process	GO:0150063	385	4	18204	49	NFIA,BMPR1B,NTRK2,GPM6A
1.976e-02	-3.92	FBXO2 (F-box protein 2)	protein interactions	26232	403	4	19454	50	LRP1B,NTM,PCDH9,FGFR3
1.989e-02	-3.92	central_nervous_system-brain-glioma-astrocytoma_Grade_III	COSMIC cancer mutations	central_nervous_system-brain-glioma-astrocytoma_Grade_III	1419	9	16828	49	ADCY2,GABRB1,HPSE2,FGFR3,CADM1,LRP1B,NRG3,PRKG1,GPC5
1.991e-02	-3.92	FGFR1 (fibroblast growth factor receptor 1)	protein interactions	2260	611	5	19454	50	ABLIM1,DTNA,NHSL1,TNIK,FGFR3
2.009e-02	-3.91	regulation of amide metabolic process	biological process	GO:0034248	81	2	18204	49	NTRK2,APOE
2.009e-02	-3.91	adult locomotory behavior	biological process	GO:0008344	81	2	18204	49	PREX2,ATP1A2
2.021e-02	-3.90	skin-face-adnexal_tumour-malignant_adnexal_tumour	COSMIC cancer mutations	skin-face-adnexal_tumour-malignant_adnexal_tumour	7	1	16828	49	FGFR3
2.021e-02	-3.90	skin-upper_leg-malignant_melanoma-nodular	COSMIC cancer mutations	skin-upper_leg-malignant_melanoma-nodular	7	1	16828	49	PREX2
2.021e-02	-3.90	skin-chest-other-seborrhoeic_keratosis	COSMIC cancer mutations	skin-chest-other-seborrhoeic_keratosis	7	1	16828	49	FGFR3
2.021e-02	-3.90	skin-adnexal_tumour-trichilemmoma	COSMIC cancer mutations	skin-adnexal_tumour-trichilemmoma	7	1	16828	49	FGFR3
2.021e-02	-3.90	skin-face-malignant_melanoma-nodular	COSMIC cancer mutations	skin-face-malignant_melanoma-nodular	7	1	16828	49	PREX2
2.021e-02	-3.90	skin-shoulder-other-seborrhoeic_keratosis	COSMIC cancer mutations	skin-shoulder-other-seborrhoeic_keratosis	7	1	16828	49	FGFR3
2.021e-02	-3.90	trichilemmoma	COSMIC cancer mutations	trichilemmoma	7	1	16828	49	FGFR3
2.021e-02	-3.90	skin-benign_melanocytic_nevus-intradermal	COSMIC cancer mutations	skin-benign_melanocytic_nevus-intradermal	7	1	16828	49	FGFR3
2.021e-02	-3.90	nevus_sebaceous	COSMIC cancer mutations	nevus_sebaceous	7	1	16828	49	FGFR3
2.021e-02	-3.90	skin-neck-other-seborrhoeic_keratosis	COSMIC cancer mutations	skin-neck-other-seborrhoeic_keratosis	7	1	16828	49	FGFR3
2.021e-02	-3.90	urinary_tract-carcinoma-transitional_cell_carcinoma	COSMIC cancer mutations	urinary_tract-carcinoma-transitional_cell_carcinoma	7	1	16828	49	FGFR3
2.021e-02	-3.90	skin-other-nevus_sebaceous	COSMIC cancer mutations	skin-other-nevus_sebaceous	7	1	16828	49	FGFR3
2.021e-02	-3.90	skin-benign_melanocytic_nevus-compound	COSMIC cancer mutations	skin-benign_melanocytic_nevus-compound	7	1	16828	49	FGFR3
2.025e-02	-3.90	FGFR3b ligand binding and activation	REACTOME pathways	R-HSA-190371	7	1	10285	30	FGFR3
2.025e-02	-3.90	Nectin/Necl trans heterodimerization	REACTOME pathways	R-HSA-420597	7	1	10285	30	CADM1
2.034e-02	-3.90	HFE-transferrin receptor complex	cellular component	GO:1990712	8	1	19108	49	BMPR1B
2.035e-02	-3.89	HAD superfamily/HAD-like	gene3d domains	3.40.50.1000	74	2	14470	43	ATP13A4,ATP1A2
2.038e-02	-3.89	LHB (luteinizing hormone subunit beta)	protein interactions	3972	8	1	19454	50	NTM
2.038e-02	-3.89	BMP15 (bone morphogenetic protein 15)	protein interactions	9210	8	1	19454	50	BMPR1B
2.038e-02	-3.89	Rasd2 (RASD family, member 2)	protein interactions	75141	8	1	19454	50	BMPR1B
2.038e-02	-3.89	CCK (cholecystokinin)	protein interactions	885	8	1	19454	50	CPE
2.038e-02	-3.89	Rps27a (ribosomal protein S27A)	protein interactions	78294	8	1	19454	50	BMPR1B
2.044e-02	-3.89	Signaling by EGFR	REACTOME pathways	R-HSA-177929	364	4	10285	30	ADCY2,FGFR3,NRG3,ITPR2
2.044e-02	-3.89	bone-Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour	COSMIC cancer mutations	bone-Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour	6023	25	16828	49	CSGALNACT1,NPAS3,FGFR3,NKAIN3,GLIS3,CST3,PTPRZ1,ATP1A2,CTNND2,ABLIM1,ADCY2,RORA,PREX2,DTNA,NTRK2,CADM1,LRP1B,NRG3,ATP13A4,SOX5,ITPR2,SPARCL1,COL5A3,ZBTB20,SLC1A3
2.056e-02	-3.88	regulation of steroid biosynthetic process	biological process	GO:0050810	82	2	18204	49	APOE,PRKG1
2.075e-02	-3.88	response to oxygen-containing compound	biological process	GO:1901700	1546	9	18204	49	ATP1A2,ITPR2,ZBTB20,SLC1A2,APOE,GABRB1,RORA,SLC1A3,ADCY2
2.078e-02	-3.87	sensory system development	biological process	GO:0048880	391	4	18204	49	GPM6A,NFIA,BMPR1B,NTRK2
2.090e-02	-3.87	LDLR (low density lipoprotein receptor)	protein interactions	3949	410	4	19454	50	MGAT4C,APOE,LRP1B,PREX2
2.103e-02	-3.86	regulation of amine transport	biological process	GO:0051952	83	2	18204	49	ATP1A2,PRKG1
2.103e-02	-3.86	sodium ion binding	molecular function	GO:0031402	8	1	18094	48	ATP1A2
2.103e-02	-3.86	P-type potassium transmembrane transporter activity	molecular function	GO:0008556	8	1	18094	48	ATP1A2
2.103e-02	-3.86	cyclic nucleotide-dependent protein kinase activity	molecular function	GO:0004690	8	1	18094	48	PRKG1
2.103e-02	-3.86	glutamate binding	molecular function	GO:0016595	8	1	18094	48	SLC1A3
2.103e-02	-3.86	BMP receptor activity	molecular function	GO:0098821	8	1	18094	48	BMPR1B
2.106e-02	-3.86	eye-uveal_tract-malignant_melanoma-spindle	COSMIC cancer mutations	eye-uveal_tract-malignant_melanoma-spindle	363	4	16828	49	CTNND2,CPE,PCDH9,PREX2
2.108e-02	-3.86	ZNF608 (zinc finger protein 608)	protein interactions	57507	87	2	19454	50	SOX5,NFIA
2.109e-02	-3.86	glial cell differentiation	biological process	GO:0010001	219	3	18204	49	NFIA,PTPRZ1,NTRK2
2.111e-02	-3.86	anion binding	molecular function	GO:0043168	2412	12	18094	48	ITPR2,PRKG1,PITPNC1,ADCY2,FGFR3,ATP13A4,NTRK2,SLC1A3,ATP1A2,TNIK,ETNPPL,BMPR1B
2.123e-02	-3.85	kidney-carcinoma-clear_cell_renal_cell_carcinoma	COSMIC cancer mutations	kidney-carcinoma-clear_cell_renal_cell_carcinoma	13924	46	16828	49	RANBP3L,ADCY2,CDH20,CPE,PCDH9,ATP1A2,GPM6A,PTPRZ1,SLC1A2,CSGALNACT1,NRXN1,SLC1A3,COL5A3,SPARCL1,ITPR2,PITPNC1,NFIA,SOX5,ATP13A4,NRG3,RORA,BMPR1B,ABLIM1,CTNND2,LSAMP,TNIK,APOE,GLIS3,NKAIN3,FGFR3,NHSL1,NPAS3,PRKG1,FBXL7,ZBTB20,GPC5,GABRB1,HPSE2,MSI2,MGAT4C,DTNA,LRP1B,CADM1,NTRK2,PREX2,FMN2
2.123e-02	-3.85	clear_cell_renal_cell_carcinoma	COSMIC cancer mutations	clear_cell_renal_cell_carcinoma	13924	46	16828	49	GPC5,ZBTB20,PREX2,LRP1B,NTRK2,DTNA,CADM1,FMN2,GABRB1,MSI2,MGAT4C,HPSE2,LSAMP,TNIK,APOE,ABLIM1,CTNND2,NPAS3,FBXL7,PRKG1,NHSL1,NKAIN3,GLIS3,FGFR3,NFIA,PITPNC1,ITPR2,SLC1A3,NRXN1,SPARCL1,COL5A3,NRG3,BMPR1B,RORA,SOX5,ATP13A4,PTPRZ1,GPM6A,ATP1A2,CPE,PCDH9,CDH20,ADCY2,RANBP3L,CSGALNACT1,SLC1A2
2.126e-02	-3.85	femur	COSMIC cancer mutations	femur	1197	8	16828	49	PTPRZ1,LRP1B,PCDH9,NRG3,GPC5,FMN2,ADCY2,HPSE2
2.127e-02	-3.85	DST (dystonin)	protein interactions	667	230	3	19454	50	NTRK2,ATP1A2,TNIK
2.134e-02	-3.85	heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process	biological process	GO:0015014	8	1	18204	49	CSGALNACT1
2.134e-02	-3.85	cerebellar granule cell precursor proliferation	biological process	GO:0021930	8	1	18204	49	RORA
2.134e-02	-3.85	positive regulation of CoA-transferase activity	biological process	GO:1905920	8	1	18204	49	APOE
2.134e-02	-3.85	cell proliferation in external granule layer	biological process	GO:0021924	8	1	18204	49	RORA
2.134e-02	-3.85	protein import	biological process	GO:0017038	8	1	18204	49	APOE
2.134e-02	-3.85	ERBB4 signaling pathway	biological process	GO:0038130	8	1	18204	49	NRG3
2.134e-02	-3.85	gamma-aminobutyric acid metabolic process	biological process	GO:0009448	8	1	18204	49	SLC1A3
2.134e-02	-3.85	meiotic cytokinesis	biological process	GO:0033206	8	1	18204	49	FMN2
2.134e-02	-3.85	cell proliferation in hindbrain	biological process	GO:0021534	8	1	18204	49	RORA
2.134e-02	-3.85	positive regulation of amyloid-beta clearance	biological process	GO:1900223	8	1	18204	49	APOE
2.134e-02	-3.85	regulation of Cdc42 protein signal transduction	biological process	GO:0032489	8	1	18204	49	APOE
2.134e-02	-3.85	regulation of L-glutamate import across plasma membrane	biological process	GO:0002036	8	1	18204	49	ATP1A2
2.134e-02	-3.85	triglyceride-rich lipoprotein particle remodeling	biological process	GO:0034370	8	1	18204	49	APOE
2.134e-02	-3.85	insulin processing	biological process	GO:0030070	8	1	18204	49	CPE
2.134e-02	-3.85	dermatan sulfate proteoglycan biosynthetic process	biological process	GO:0050651	8	1	18204	49	CSGALNACT1
2.134e-02	-3.85	response to mechanical stimulus	biological process	GO:0009612	220	3	18204	49	SLC1A3,ATP1A2,NRXN1
2.140e-02	-3.84	Villin_headpiece	interpro domains	IPR003128	8	1	18521	50	ABLIM1
2.140e-02	-3.84	AC_N	interpro domains	IPR032628	8	1	18521	50	ADCY2
2.140e-02	-3.84	Adcy	interpro domains	IPR030672	8	1	18521	50	ADCY2
2.140e-02	-3.84	Chond_GalNAc	interpro domains	IPR008428	8	1	18521	50	CSGALNACT1
2.140e-02	-3.84	Villin_headpiece_dom_sf	interpro domains	IPR036886	8	1	18521	50	ABLIM1
2.147e-02	-3.84	GLYPICAN	prosite domains	PS01207	6	1	12186	44	GPC5
2.151e-02	-3.84	proteoglycan metabolic process	biological process	GO:0006029	84	2	18204	49	CSGALNACT1,BMPR1B
2.151e-02	-3.84	regulation of sodium ion transport	biological process	GO:0002028	84	2	18204	49	ATP1A2,NKAIN3
2.151e-02	-3.84	L-amino acid transport	biological process	GO:0015807	84	2	18204	49	SLC1A2,SLC1A3
2.153e-02	-3.84	RAP2A (RAP2A, member of RAS oncogene family)	protein interactions	5911	88	2	19454	50	TNIK,BMPR1B
2.160e-02	-3.84	Glycosaminoglycan biosynthesis, chondroitin sulfate backbone	KEGG pathways	M00058	6	1	7161	26	CSGALNACT1
2.160e-02	-3.84	Glycosaminoglycan biosynthesis, chondroitin sulfate backbone	KEGG pathways	hsa_M00058	6	1	7161	26	CSGALNACT1
2.168e-02	-3.83	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-hairy_cell_leukaemia	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-hairy_cell_leukaemia	1440	9	16828	49	LRP1B,PTPRZ1,PREX2,FMN2,NRXN1,CDH20,FGFR3,CTNND2,COL5A3
2.168e-02	-3.83	hairy_cell_leukaemia	COSMIC cancer mutations	hairy_cell_leukaemia	1440	9	16828	49	COL5A3,CTNND2,FGFR3,CDH20,NRXN1,FMN2,PREX2,PTPRZ1,LRP1B
2.175e-02	-3.83	CTSB (cathepsin B)	protein interactions	1508	232	3	19454	50	CST3,APOE,MSI2
2.175e-02	-3.83	Dopamine Activation of Neurological Reward System	SMPDB pathways	SMP0000308	6	1	1369	5	ADCY2
2.175e-02	-3.83	Intracellular Signalling Through PGD2 receptor and Prostaglandin D2	SMPDB pathways	SMP0000343	6	1	1369	5	ADCY2
2.176e-02	-3.83	DAP12 interactions	REACTOME pathways	R-HSA-2172127	371	4	10285	30	FGFR3,ADCY2,ITPR2,NRG3
2.182e-02	-3.82	VHP	pfam domains	PF02209	8	1	17795	49	ABLIM1
2.182e-02	-3.82	CHGN	pfam domains	PF05679	8	1	17795	49	CSGALNACT1
2.182e-02	-3.82	AC_N	pfam domains	PF16214	8	1	17795	49	ADCY2
2.186e-02	-3.82	PDZ domain binding	molecular function	GO:0030165	86	2	18094	48	DTNA,CADM1
2.199e-02	-3.82	oligodendrocyte differentiation	biological process	GO:0048709	85	2	18204	49	PTPRZ1,NTRK2
2.201e-02	-3.82	organic anion transport	biological process	GO:0015711	398	4	18204	49	NTRK2,SLC1A2,APOE,SLC1A3
2.224e-02	-3.81	HMG20A (high mobility group 20A)	protein interactions	10363	234	3	19454	50	NFIA,DTNA,SOX5
2.233e-02	-3.80	endomembrane system	cellular component	GO:0012505	4764	19	19108	49	CPE,ITPR2,ATP13A4,MGAT4C,TNIK,NTRK2,PRKG1,APOE,FMN2,RANBP3L,CST3,COL5A3,FGFR3,SPARCL1,NRXN1,ATP1A2,CSGALNACT1,GPC5,GABRB1
2.234e-02	-3.80	single-stranded RNA binding	molecular function	GO:0003727	87	2	18094	48	MSI2,RBMS3
2.244e-02	-3.80	Ion channel transport	REACTOME pathways	R-HSA-983712	209	3	10285	30	GABRB1,ATP1A2,ATP13A4
2.247e-02	-3.80	central nervous system neuron development	biological process	GO:0021954	86	2	18204	49	NTRK2,GABRB1
2.272e-02	-3.78	human chr3p24.1	chromosome location	human chr3p24.1	12	1	26134	50	RBMS3
2.273e-02	-3.78	Signaling by PDGF	REACTOME pathways	R-HSA-186797	376	4	10285	30	ITPR2,NRG3,ADCY2,FGFR3
2.275e-02	-3.78	ACTIVIN2R	prints domains	PR00653	6	1	5227	20	BMPR1B
2.285e-02	-3.78	platelet dense tubular network membrane	cellular component	GO:0031095	9	1	19108	49	ITPR2
2.290e-02	-3.78	CACNA2D3 (calcium voltage-gated channel auxiliary subunit alpha2delta 3)	protein interactions	55799	9	1	19454	50	APOE
2.290e-02	-3.78	LINC02582 (long intergenic non-protein coding RNA 2582)	protein interactions	100505817	9	1	19454	50	APOE
2.290e-02	-3.78	KLB (klotho beta)	protein interactions	152831	9	1	19454	50	FGFR3
2.290e-02	-3.78	GUSBP1 (GUSB pseudogene 1)	protein interactions	728411	9	1	19454	50	FGFR3
2.290e-02	-3.78	VEPH1 (ventricular zone expressed PH domain containing 1)	protein interactions	79674	9	1	19454	50	BMPR1B
2.292e-02	-3.78	DGUOK (deoxyguanosine kinase)	protein interactions	1716	91	2	19454	50	NTM,GPM6A
2.293e-02	-3.78	cytoplasmic vesicle	cellular component	GO:0031410	2521	12	19108	49	CST3,SLC1A3,FGFR3,ATP1A2,ITPR2,CPE,ATP13A4,TNIK,NTRK2,PRKG1,APOE,FMN2
2.299e-02	-3.77	CAMK2A (calcium/calmodulin dependent protein kinase II alpha)	protein interactions	815	237	3	19454	50	ITPR2,GPM6A,SOX5
2.306e-02	-3.77	junctional	COSMIC cancer mutations	junctional	8	1	16828	49	FGFR3
2.306e-02	-3.77	skin-chest-malignant_melanoma-nodular	COSMIC cancer mutations	skin-chest-malignant_melanoma-nodular	8	1	16828	49	PREX2
2.306e-02	-3.77	urinary_tract-ureter-carcinoma-transitional_cell_carcinoma	COSMIC cancer mutations	urinary_tract-ureter-carcinoma-transitional_cell_carcinoma	8	1	16828	49	FGFR3
2.306e-02	-3.77	cervix-in_situ_neoplasm-cervical_intraepithelial_neoplasia_Grade_I	COSMIC cancer mutations	cervix-in_situ_neoplasm-cervical_intraepithelial_neoplasia_Grade_I	8	1	16828	49	FGFR3
2.306e-02	-3.77	cervical_intraepithelial_neoplasia_Grade_I	COSMIC cancer mutations	cervical_intraepithelial_neoplasia_Grade_I	8	1	16828	49	FGFR3
2.306e-02	-3.77	actinic_keratosis	COSMIC cancer mutations	actinic_keratosis	8	1	16828	49	FGFR3
2.306e-02	-3.77	trichoblastoma	COSMIC cancer mutations	trichoblastoma	8	1	16828	49	FGFR3
2.311e-02	-3.77	Release of Hh-Np from the secreting cell	REACTOME pathways	R-HSA-5362798	8	1	10285	30	GPC5
2.325e-02	-3.76	forearm	COSMIC cancer mutations	forearm	81	2	16828	49	FGFR3,PREX2
2.331e-02	-3.76	amyloid-beta binding	molecular function	GO:0001540	89	2	18094	48	CST3,APOE
2.332e-02	-3.76	intracellular vesicle	cellular component	GO:0097708	2527	12	19108	49	ATP1A2,SLC1A3,FGFR3,CST3,FMN2,APOE,PRKG1,NTRK2,TNIK,ATP13A4,CPE,ITPR2
2.339e-02	-3.76	RLN1 (relaxin 1)	protein interactions	6013	92	2	19454	50	CPE,LRP1B
2.339e-02	-3.76	FNTA (farnesyltransferase, CAAX box, subunit alpha)	protein interactions	2339	92	2	19454	50	FGFR3,TNIK
2.339e-02	-3.76	POTEI (POTE ankyrin domain family member I)	protein interactions	653269	92	2	19454	50	FGFR3,DTNA
2.353e-02	-3.75	Villin headpiece domain	gene3d domains	1.10.950.10	8	1	14470	43	ABLIM1
2.385e-02	-3.74	skin-neck-malignant_melanoma	COSMIC cancer mutations	skin-neck-malignant_melanoma	1223	8	16828	49	GPC5,PREX2,ATP1A2,LRP1B,ATP13A4,COL5A3,CTNND2,ADCY2
2.387e-02	-3.74	ARHGEF6 (Rac/Cdc42 guanine nucleotide exchange factor 6)	protein interactions	9459	93	2	19454	50	BMPR1B,ABLIM1
2.395e-02	-3.73	positive regulation of lipid biosynthetic process	biological process	GO:0046889	89	2	18204	49	ZBTB20,APOE
2.397e-02	-3.73	polyamine transmembrane transport	biological process	GO:1902047	9	1	18204	49	ATP13A4
2.397e-02	-3.73	cholesterol catabolic process	biological process	GO:0006707	9	1	18204	49	APOE
2.397e-02	-3.73	negative regulation of striated muscle contraction	biological process	GO:0045988	9	1	18204	49	ATP1A2
2.397e-02	-3.73	sterol catabolic process	biological process	GO:0016127	9	1	18204	49	APOE
2.397e-02	-3.73	positive regulation of synapse maturation	biological process	GO:0090129	9	1	18204	49	NRXN1
2.397e-02	-3.73	activated T cell proliferation	biological process	GO:0050798	9	1	18204	49	CADM1
2.404e-02	-3.73	Activin_recp	interpro domains	IPR000472	9	1	18521	50	BMPR1B
2.404e-02	-3.73	Prot_inh_cystat_CS	interpro domains	IPR018073	9	1	18521	50	CST3
2.404e-02	-3.73	Fol_N	interpro domains	IPR003645	9	1	18521	50	SPARCL1
2.420e-02	-3.72	ACTG1 (actin gamma 1)	protein interactions	71	429	4	19454	50	APOE,FMN2,ABLIM1,TNIK
2.435e-02	-3.72	QSER1 (glutamine and serine rich 1)	protein interactions	79832	94	2	19454	50	SOX5,NFIA
2.435e-02	-3.72	FOXP4 (forkhead box P4)	protein interactions	116113	94	2	19454	50	NFIA,SOX5
2.435e-02	-3.72	WWC1 (WW and C2 domain containing 1)	protein interactions	23286	94	2	19454	50	TNIK,ABLIM1
2.435e-02	-3.72	GRIN1 (glutamate ionotropic receptor NMDA type subunit 1)	protein interactions	2902	94	2	19454	50	NTRK2,FGFR3
2.452e-02	-3.71	Activin_recp	pfam domains	PF01064	9	1	17795	49	BMPR1B
2.453e-02	-3.71	Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour	COSMIC cancer mutations	Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour	7434	29	16828	49	CTNND2,ABLIM1,ADCY2,PTPRZ1,ATP1A2,TNIK,FGFR3,NKAIN3,GLIS3,CST3,CSGALNACT1,PRKG1,NPAS3,SPARCL1,COL5A3,ZBTB20,SLC1A3,NRXN1,ITPR2,ATP13A4,SOX5,RORA,FMN2,PREX2,CADM1,LRP1B,NTRK2,DTNA,NRG3
2.459e-02	-3.71	human chr5p15.1	chromosome location	human chr5p15.1	13	1	26134	50	FBXL7
2.470e-02	-3.70	EGF-like_dom	interpro domains	IPR000742	232	3	18521	50	LRP1B,NRXN1,NRG3
2.495e-02	-3.69	axon	cellular component	GO:0030424	650	5	19108	49	DTNA,SLC1A2,NTRK2,PCDH9,GPM6A
2.496e-02	-3.69	response to BMP	biological process	GO:0071772	91	2	18204	49	BMPR1B,NFIA
2.496e-02	-3.69	cellular response to BMP stimulus	biological process	GO:0071773	91	2	18204	49	NFIA,BMPR1B
2.501e-02	-3.69	GS	prosite domains	PS51256	7	1	12186	44	BMPR1B
2.528e-02	-3.68	Opioid Signalling	REACTOME pathways	R-HSA-111885	85	2	10285	30	ITPR2,ADCY2
2.534e-02	-3.68	Vasopressin Regulation of Water Homeostasis	SMPDB pathways	SMP0000322	7	1	1369	5	ADCY2
2.536e-02	-3.67	perineuronal net	cellular component	GO:0072534	10	1	19108	49	PTPRZ1
2.541e-02	-3.67	SERPINB11 (serpin family B member 11)	protein interactions	89778	10	1	19454	50	CPE
2.541e-02	-3.67	Vbp1 (von Hippel-Lindau binding protein 1)	protein interactions	22327	10	1	19454	50	ABLIM1
2.541e-02	-3.67	P2rx7 (purinergic receptor P2X 7)	protein interactions	29665	10	1	19454	50	PTPRZ1
2.541e-02	-3.67	GSG1 (germ cell associated 1)	protein interactions	83445	10	1	19454	50	PITPNC1
2.541e-02	-3.67	BANK1 (B cell scaffold protein with ankyrin repeats 1)	protein interactions	55024	10	1	19454	50	ITPR2
2.541e-02	-3.67	SLC8A2 (solute carrier family 8 member A2)	protein interactions	6543	10	1	19454	50	GPM6A
2.541e-02	-3.67	Smurf2 (SMAD specific E3 ubiquitin protein ligase 2)	protein interactions	66313	10	1	19454	50	GLIS3
2.541e-02	-3.67	ZNF563 (zinc finger protein 563)	protein interactions	147837	10	1	19454	50	LRP1B
2.541e-02	-3.67	CALB2 (calbindin 2)	protein interactions	794	10	1	19454	50	GPM6A
2.541e-02	-3.67	CHRDL1 (chordin like 1)	protein interactions	91851	10	1	19454	50	LRP1B
2.585e-02	-3.66	NCOR2 (nuclear receptor corepressor 2)	protein interactions	9612	248	3	19454	50	TNIK,SOX5,NFIA
2.591e-02	-3.65	Bowen_disease	COSMIC cancer mutations	Bowen_disease	9	1	16828	49	FGFR3
2.591e-02	-3.65	ovary-low_malignant_potential_(borderline)_tumour-Brenner_tumour	COSMIC cancer mutations	ovary-low_malignant_potential_(borderline)_tumour-Brenner_tumour	9	1	16828	49	FGFR3
2.591e-02	-3.65	skin-chest-malignant_melanoma-superficial_spreading	COSMIC cancer mutations	skin-chest-malignant_melanoma-superficial_spreading	9	1	16828	49	PREX2
2.591e-02	-3.65	epidermal_nevus	COSMIC cancer mutations	epidermal_nevus	9	1	16828	49	FGFR3
2.591e-02	-3.65	skin-upper_leg-malignant_melanoma-superficial_spreading	COSMIC cancer mutations	skin-upper_leg-malignant_melanoma-superficial_spreading	9	1	16828	49	PREX2
2.591e-02	-3.65	compound	COSMIC cancer mutations	compound	9	1	16828	49	FGFR3
2.591e-02	-3.65	in_situ_epithelial_neoplasm	COSMIC cancer mutations	in_situ_epithelial_neoplasm	9	1	16828	49	FGFR3
2.591e-02	-3.65	skin-other-seborrhoeic_keratosis	COSMIC cancer mutations	skin-other-seborrhoeic_keratosis	9	1	16828	49	FGFR3
2.591e-02	-3.65	skin-benign_melanocytic_nevus-congenital	COSMIC cancer mutations	skin-benign_melanocytic_nevus-congenital	9	1	16828	49	FGFR3
2.599e-02	-3.65	enzyme-linked receptor protein signaling pathway	biological process	GO:0007167	626	5	18204	49	FGFR3,NRG3,NTRK2,BMPR1B,NFIA
2.612e-02	-3.65	transmembrane transporter activity	molecular function	GO:0022857	1110	7	18094	48	ATP13A4,GPM6A,SLC1A2,GABRB1,SLC1A3,ITPR2,ATP1A2
2.618e-02	-3.64	axon development	biological process	GO:0061564	420	4	18204	49	PRKG1,BMPR1B,PTPRZ1,NRXN1
2.618e-02	-3.64	organic substance transport	biological process	GO:0071702	1881	10	18204	49	SLC1A2,CPE,NTRK2,LRP1B,PITPNC1,ATP13A4,FMN2,APOE,SLC1A3,RANBP3L
2.622e-02	-3.64	neurotrophin binding	molecular function	GO:0043121	10	1	18094	48	NTRK2
2.622e-02	-3.64	phosphatidylinositol transfer activity	molecular function	GO:0008526	10	1	18094	48	PITPNC1
2.622e-02	-3.64	polyamine transmembrane transporter activity	molecular function	GO:0015203	10	1	18094	48	ATP13A4
2.625e-02	-3.64	cell surface	cellular component	GO:0009986	896	6	19108	49	SLC1A2,FGFR3,SLC1A3,NRXN1,GPC5,ATP1A2
2.631e-02	-3.64	DNAAF2 (dynein axonemal assembly factor 2)	protein interactions	55172	98	2	19454	50	GPM6A,LSAMP
2.631e-02	-3.64	FRS2 (fibroblast growth factor receptor substrate 2)	protein interactions	10818	98	2	19454	50	NTRK2,FGFR3
2.631e-02	-3.64	FRAS1 (Fraser extracellular matrix complex subunit 1)	protein interactions	80144	98	2	19454	50	MGAT4C,HPSE2
2.636e-02	-3.64	GS	smart domains	SM00467	7	1	9717	37	BMPR1B
2.639e-02	-3.63	PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling	REACTOME pathways	R-HSA-6811558	87	2	10285	30	NRG3,FGFR3
2.645e-02	-3.63	dermatan sulfate biosynthesis	BIOCYC pathways	HUMAN_PWY-6571	12	1	902	2	CSGALNACT1
2.646e-02	-3.63	human chr2p16.3	chromosome location	human chr2p16.3	14	1	26134	50	NRXN1
2.649e-02	-3.63	HUDSXLRNA	prints domains	PR00961	7	1	5227	20	RBMS3
2.654e-02	-3.63	upper_arm	COSMIC cancer mutations	upper_arm	582	5	16828	49	PREX2,LRP1B,FMN2,FGFR3,ITPR2
2.660e-02	-3.63	response to histamine	biological process	GO:0034776	10	1	18204	49	GABRB1
2.660e-02	-3.63	regulation of behavioral fear response	biological process	GO:2000822	10	1	18204	49	APOE
2.660e-02	-3.63	regulation of mesenchymal stem cell differentiation	biological process	GO:2000739	10	1	18204	49	SOX5
2.660e-02	-3.63	postsynaptic membrane assembly	biological process	GO:0097104	10	1	18204	49	NRXN1
2.660e-02	-3.63	cellular response to brain-derived neurotrophic factor stimulus	biological process	GO:1990416	10	1	18204	49	NTRK2
2.660e-02	-3.63	substrate-independent telencephalic tangential migration	biological process	GO:0021826	10	1	18204	49	NRG3
2.660e-02	-3.63	learned vocalization behavior or vocal learning	biological process	GO:0098598	10	1	18204	49	NRXN1
2.660e-02	-3.63	nitric oxide-cGMP-mediated signaling	biological process	GO:0038060	10	1	18204	49	APOE
2.660e-02	-3.63	postsynaptic density assembly	biological process	GO:0097107	10	1	18204	49	NRXN1
2.660e-02	-3.63	cAMP biosynthetic process	biological process	GO:0006171	10	1	18204	49	ADCY2
2.660e-02	-3.63	high-density lipoprotein particle assembly	biological process	GO:0034380	10	1	18204	49	APOE
2.660e-02	-3.63	negative regulation of sterol biosynthetic process	biological process	GO:0106119	10	1	18204	49	APOE
2.660e-02	-3.63	regulation of CoA-transferase activity	biological process	GO:1905918	10	1	18204	49	APOE
2.660e-02	-3.63	trans-synaptic signaling, modulating synaptic transmission	biological process	GO:0099550	10	1	18204	49	NTRK2
2.660e-02	-3.63	negative regulation of cholesterol biosynthetic process	biological process	GO:0045541	10	1	18204	49	APOE
2.660e-02	-3.63	retinal rod cell development	biological process	GO:0046548	10	1	18204	49	NTRK2
2.660e-02	-3.63	substrate-independent telencephalic tangential interneuron migration	biological process	GO:0021843	10	1	18204	49	NRG3
2.668e-02	-3.62	MIR_dom_sf	interpro domains	IPR036300	10	1	18521	50	ITPR2
2.668e-02	-3.62	PAS_fold_3	interpro domains	IPR013655	10	1	18521	50	NPAS3
2.668e-02	-3.62	MIR_motif	interpro domains	IPR016093	10	1	18521	50	ITPR2
2.680e-02	-3.62	TNKS (tankyrase)	protein interactions	8658	99	2	19454	50	TNIK,PCDH9
2.683e-02	-3.62	ATPase-coupled transmembrane transporter activity	molecular function	GO:0042626	96	2	18094	48	ATP1A2,ATP13A4
2.691e-02	-3.62	response to abiotic stimulus	biological process	GO:0009628	1100	7	18204	49	SLC1A2,ITPR2,NRXN1,ATP1A2,SLC1A3,RORA,FMN2
2.693e-02	-3.61	NCK2 (NCK adaptor protein 2)	protein interactions	8440	252	3	19454	50	TNIK,NHSL1,NTRK2
2.698e-02	-3.61	developmental growth	biological process	GO:0048589	424	4	18204	49	PRKG1,SLC1A2,BMPR1B,FGFR3
2.698e-02	-3.61	growth	biological process	GO:0040007	424	4	18204	49	FGFR3,SLC1A2,BMPR1B,PRKG1
2.701e-02	-3.61	anchoring junction	cellular component	GO:0070161	902	6	19108	49	CADM1,PCDH9,FGFR3,CDH20,CTNND2,ATP1A2
2.702e-02	-3.61	Bile secretion	KEGG pathways	hsa04976	71	2	7161	26	ADCY2,ATP1A2
2.702e-02	-3.61	Bile secretion	KEGG pathways	ko04976	71	2	7161	26	ADCY2,ATP1A2
2.702e-02	-3.61	cell motility	biological process	GO:0048870	1101	7	18204	49	PRKG1,CDH20,GPC5,NRG3,NTRK2,GPM6A,FMN2
2.719e-02	-3.61	extrinsic component of plasma membrane	cellular component	GO:0019897	100	2	19108	49	DTNA,CDH20
2.719e-02	-3.60	Tyr_kinase_AS	interpro domains	IPR008266	95	2	18521	50	FGFR3,NTRK2
2.719e-02	-3.60	EGF-type_Asp/Asn_hydroxyl_site	interpro domains	IPR000152	95	2	18521	50	LRP1B,NRXN1
2.720e-02	-3.60	PAS_3	pfam domains	PF08447	10	1	17795	49	NPAS3
2.720e-02	-3.60	MIR	pfam domains	PF02815	10	1	17795	49	ITPR2
2.731e-02	-3.60	ATP4A (ATPase H+/K+ transporting subunit alpha)	protein interactions	495	100	2	19454	50	ATP1A2,GPM6A
2.731e-02	-3.60	APBA1 (amyloid beta precursor protein binding family A member 1)	protein interactions	320	100	2	19454	50	NRXN1,ABLIM1
2.737e-02	-3.60	pancreas-other-adenoma	COSMIC cancer mutations	pancreas-other-adenoma	224	3	16828	49	PCDH9,CTNND2,BMPR1B
2.756e-02	-3.59	negative regulation of response to wounding	biological process	GO:1903035	96	2	18204	49	PRKG1,APOE
2.758e-02	-3.59	monoatomic cation transmembrane transport	biological process	GO:0098655	636	5	18204	49	ATP1A2,SLC1A3,ATP13A4,GPM6A,ITPR2
2.759e-02	-3.59	viral process	biological process	GO:0016032	243	3	18204	49	MGAT4C,APOE,NFIA
2.767e-02	-3.59	signal transduction	biological process	GO:0007165	4637	19	18204	49	NFIA,PRKG1,FGFR3,PITPNC1,FMN2,RORA,PREX2,ADCY2,ATP1A2,NRG3,TNIK,CPE,BMPR1B,CTNND2,ITPR2,DTNA,SPARCL1,APOE,NTRK2
2.780e-02	-3.58	intracellular monoatomic cation homeostasis	biological process	GO:0030003	428	4	18204	49	SLC1A3,ATP1A2,APOE,ATP13A4
2.786e-02	-3.58	platelet dense tubular network	cellular component	GO:0031094	11	1	19108	49	ITPR2
2.786e-02	-3.58	perisynaptic extracellular matrix	cellular component	GO:0098966	11	1	19108	49	PTPRZ1
2.786e-02	-3.58	positive regulation of biological process	biological process	GO:0048518	6326	24	18204	49	PTPRZ1,ZBTB20,PRKG1,NFIA,APOE,NTRK2,HPSE2,GPC5,TNIK,FMN2,RORA,GPM6A,GLIS3,FGFR3,SLC1A3,CADM1,RBMS3,SOX5,SLC1A2,RANBP3L,NPAS3,NRXN1,ATP1A2,BMPR1B
2.792e-02	-3.58	SYTL1 (synaptotagmin like 1)	protein interactions	84958	11	1	19454	50	NRXN1
2.792e-02	-3.58	NEUROD4 (neuronal differentiation 4)	protein interactions	58158	11	1	19454	50	GABRB1
2.792e-02	-3.58	Cobll1 (Cobl-like 1)	protein interactions	319876	11	1	19454	50	ABLIM1
2.792e-02	-3.58	NTS (neurotensin)	protein interactions	4922	11	1	19454	50	CPE
2.792e-02	-3.58	Gtf2e2 (general transcription factor II E, polypeptide 2 (beta subunit))	protein interactions	68153	11	1	19454	50	NHSL1
2.792e-02	-3.58	ADCY5 (adenylate cyclase 5)	protein interactions	111	11	1	19454	50	ADCY2
2.792e-02	-3.58	CCDC17 (coiled-coil domain containing 17)	protein interactions	149483	11	1	19454	50	FGFR3
2.792e-02	-3.58	SYN3 (synapsin III)	protein interactions	8224	11	1	19454	50	GPM6A
2.792e-02	-3.58	AQP5 (aquaporin 5)	protein interactions	362	11	1	19454	50	ATP1A2
2.810e-02	-3.57	amino acid transmembrane transport	biological process	GO:0003333	97	2	18204	49	SLC1A3,SLC1A2
2.811e-02	-3.57	PI3K/AKT Signaling in Cancer	REACTOME pathways	R-HSA-2219528	90	2	10285	30	NRG3,FGFR3
2.832e-02	-3.56	human chr8q12.3	chromosome location	human chr8q12.3	15	1	26134	50	NKAIN3
2.832e-02	-3.56	CTSV (cathepsin V)	protein interactions	1515	102	2	19454	50	CST3,CSGALNACT1
2.842e-02	-3.56	Signaling by the B Cell Receptor (BCR)	REACTOME pathways	R-HSA-983705	229	3	10285	30	FGFR3,NRG3,ITPR2
2.851e-02	-3.56	PROTEIN_KINASE_DOM	prosite domains	PS50011	480	5	12186	44	NTRK2,BMPR1B,FGFR3,PRKG1,TNIK
2.853e-02	-3.56	HP	prosite domains	PS51089	8	1	12186	44	ABLIM1
2.869e-02	-3.55	Platelet homeostasis	REACTOME pathways	R-HSA-418346	91	2	10285	30	PRKG1,ITPR2
2.875e-02	-3.55	lung-carcinoma-pleomorphic_carcinoma	COSMIC cancer mutations	lung-carcinoma-pleomorphic_carcinoma	10	1	16828	49	FGFR3
2.875e-02	-3.55	intradermal	COSMIC cancer mutations	intradermal	10	1	16828	49	FGFR3
2.875e-02	-3.55	skin-back-malignant_melanoma-nodular	COSMIC cancer mutations	skin-back-malignant_melanoma-nodular	10	1	16828	49	PREX2
2.875e-02	-3.55	renal_cell_carcinoma_unclassified	COSMIC cancer mutations	renal_cell_carcinoma_unclassified	10	1	16828	49	FGFR3
2.875e-02	-3.55	cervix-in_situ_neoplasm-cervical_intraepithelial_neoplasia_Grade_III	COSMIC cancer mutations	cervix-in_situ_neoplasm-cervical_intraepithelial_neoplasia_Grade_III	10	1	16828	49	FGFR3
2.875e-02	-3.55	kidney-carcinoma-renal_cell_carcinoma_unclassified	COSMIC cancer mutations	kidney-carcinoma-renal_cell_carcinoma_unclassified	10	1	16828	49	FGFR3
2.875e-02	-3.55	cervical_intraepithelial_neoplasia_Grade_III	COSMIC cancer mutations	cervical_intraepithelial_neoplasia_Grade_III	10	1	16828	49	FGFR3
2.879e-02	-3.55	FLOT1 (flotillin 1)	protein interactions	10211	453	4	19454	50	FMN2,DTNA,SOX5,ABLIM1
2.880e-02	-3.55	Adenylate cyclase activating pathway	REACTOME pathways	R-HSA-170660	10	1	10285	30	ADCY2
2.880e-02	-3.55	Signaling by FGFR3 fusions in cancer	REACTOME pathways	R-HSA-8853334	10	1	10285	30	FGFR3
2.880e-02	-3.55	PI3K events in ERBB4 signaling	REACTOME pathways	R-HSA-1250342	10	1	10285	30	NRG3
2.880e-02	-3.55	sulfur amino acid transmembrane transporter activity	molecular function	GO:0000099	11	1	18094	48	SLC1A2
2.880e-02	-3.55	acetylcholine receptor binding	molecular function	GO:0033130	11	1	18094	48	NRXN1
2.884e-02	-3.55	CSGALNACT2 (chondroitin sulfate N-acetylgalactosaminyltransferase 2)	protein interactions	55454	103	2	19454	50	CSGALNACT1,MGAT4C
2.884e-02	-3.55	RAB6B (RAB6B, member RAS oncogene family)	protein interactions	51560	103	2	19454	50	GPM6A,BMPR1B
2.885e-02	-3.55	inorganic ion homeostasis	biological process	GO:0098771	433	4	18204	49	ATP1A2,SLC1A3,ATP13A4,APOE
2.885e-02	-3.55	adrenal_gland-adrenal_gland-adrenal_cortical_adenoma-aldosterone_producing	COSMIC cancer mutations	adrenal_gland-adrenal_gland-adrenal_cortical_adenoma-aldosterone_producing	91	2	16828	49	LRP1B,ADCY2
2.892e-02	-3.54	Bile Acid Indirect Signalling Pathway	SMPDB pathways	SMP0086851	8	1	1369	5	FGFR3
2.892e-02	-3.54	Intracellular Signalling Through Prostacyclin Receptor and Prostacyclin	SMPDB pathways	SMP0000354	8	1	1369	5	ADCY2
2.893e-02	-3.54	amino acid transmembrane transporter activity	molecular function	GO:0015171	100	2	18094	48	SLC1A2,SLC1A3
2.897e-02	-3.54	large_intestine-caecum-adenoma	COSMIC cancer mutations	large_intestine-caecum-adenoma	229	3	16828	49	LRP1B,HPSE2,CTNND2
2.917e-02	-3.53	phospholipid transport	biological process	GO:0015914	99	2	18204	49	PITPNC1,APOE
2.922e-02	-3.53	ectodermal placode formation	biological process	GO:0060788	11	1	18204	49	NRG3
2.922e-02	-3.53	negative regulation of platelet aggregation	biological process	GO:0090331	11	1	18204	49	PRKG1
2.922e-02	-3.53	polyamine transport	biological process	GO:0015846	11	1	18204	49	ATP13A4
2.922e-02	-3.53	physiological cardiac muscle hypertrophy	biological process	GO:0003301	11	1	18204	49	PRKG1
2.922e-02	-3.53	ectodermal placode morphogenesis	biological process	GO:0071697	11	1	18204	49	NRG3
2.922e-02	-3.53	negative regulation of neuron migration	biological process	GO:2001223	11	1	18204	49	NRG3
2.922e-02	-3.53	establishment or maintenance of transmembrane electrochemical gradient	biological process	GO:0010248	11	1	18204	49	ATP1A2
2.922e-02	-3.53	heparin biosynthetic process	biological process	GO:0030210	11	1	18204	49	CSGALNACT1
2.922e-02	-3.53	antral ovarian follicle growth	biological process	GO:0001547	11	1	18204	49	BMPR1B
2.922e-02	-3.53	cell growth involved in cardiac muscle cell development	biological process	GO:0061049	11	1	18204	49	PRKG1
2.922e-02	-3.53	regulation of fear response	biological process	GO:1903365	11	1	18204	49	APOE
2.922e-02	-3.53	glutamate secretion	biological process	GO:0014047	11	1	18204	49	NTRK2
2.922e-02	-3.53	lactone metabolic process	biological process	GO:1901334	11	1	18204	49	ATP1A2
2.922e-02	-3.53	physiological muscle hypertrophy	biological process	GO:0003298	11	1	18204	49	PRKG1
2.922e-02	-3.53	regulation of receptor catabolic process	biological process	GO:2000644	11	1	18204	49	APOE
2.922e-02	-3.53	negative regulation of cholesterol metabolic process	biological process	GO:0090206	11	1	18204	49	APOE
2.922e-02	-3.53	L-ascorbic acid metabolic process	biological process	GO:0019852	11	1	18204	49	ATP1A2
2.927e-02	-3.53	Post-translational modification: synthesis of GPI-anchored proteins	REACTOME pathways	R-HSA-163125	92	2	10285	30	NTM,LSAMP
2.931e-02	-3.53	Tyr_kinase_rcpt_2_CS	interpro domains	IPR002011	11	1	18521	50	NTRK2
2.931e-02	-3.53	Fib_collagen_C	interpro domains	IPR000885	11	1	18521	50	COL5A3
2.931e-02	-3.53	RanBP1-like	interpro domains	IPR045255	11	1	18521	50	RANBP3L
2.931e-02	-3.53	Ran_bind_dom	interpro domains	IPR000156	11	1	18521	50	RANBP3L
2.935e-02	-3.53	Laminin	gene3d domains	2.10.25.10	226	3	14470	43	NRG3,LRP1B,NRXN1
2.936e-02	-3.53	HUNK (hormonally up-regulated Neu-associated kinase)	protein interactions	30811	104	2	19454	50	SPARCL1,ABLIM1
2.970e-02	-3.52	intracellular monoatomic ion homeostasis	biological process	GO:0006873	437	4	18204	49	ATP1A2,SLC1A3,ATP13A4,APOE
2.972e-02	-3.52	response to alkaloid	biological process	GO:0043279	100	2	18204	49	SLC1A3,SLC1A2
2.979e-02	-3.51	active transmembrane transporter activity	molecular function	GO:0022804	444	4	18094	48	ATP13A4,SLC1A3,SLC1A2,ATP1A2
2.988e-02	-3.51	COLFI	pfam domains	PF01410	11	1	17795	49	COL5A3
2.988e-02	-3.51	Ran_BP1	pfam domains	PF00638	11	1	17795	49	RANBP3L
3.003e-02	-3.51	aldosterone_producing	COSMIC cancer mutations	aldosterone_producing	93	2	16828	49	LRP1B,ADCY2
3.007e-02	-3.50	VHP	smart domains	SM00153	8	1	9717	37	ABLIM1
3.027e-02	-3.50	cholesterol homeostasis	biological process	GO:0042632	101	2	18204	49	APOE,RORA
3.035e-02	-3.49	banded collagen fibril	cellular component	GO:0098643	12	1	19108	49	COL5A3
3.035e-02	-3.49	sodium:potassium-exchanging ATPase complex	cellular component	GO:0005890	12	1	19108	49	ATP1A2
3.035e-02	-3.49	synapse-associated extracellular matrix	cellular component	GO:0099535	12	1	19108	49	PTPRZ1
3.035e-02	-3.49	fibrillar collagen trimer	cellular component	GO:0005583	12	1	19108	49	COL5A3
3.042e-02	-3.49	TREM2 (triggering receptor expressed on myeloid cells 2)	protein interactions	54209	12	1	19454	50	APOE
3.042e-02	-3.49	LMP-1 (latent membrane protein LMP-1)	protein interactions	3783750	12	1	19454	50	TNIK
3.042e-02	-3.49	BAMBI (BMP and activin membrane bound inhibitor)	protein interactions	25805	12	1	19454	50	BMPR1B
3.042e-02	-3.49	NTF4 (neurotrophin 4)	protein interactions	4909	12	1	19454	50	NTRK2
3.042e-02	-3.49	OAS2 (2'-5'-oligoadenylate synthetase 2)	protein interactions	4939	12	1	19454	50	PRKG1
3.042e-02	-3.49	ART4 (ADP-ribosyltransferase 4 (inactive) (Dombrock blood group))	protein interactions	420	12	1	19454	50	GPM6A
3.046e-02	-3.49	Negative regulation of the PI3K/AKT network	REACTOME pathways	R-HSA-199418	94	2	10285	30	NRG3,FGFR3
3.082e-02	-3.48	sterol homeostasis	biological process	GO:0055092	102	2	18204	49	RORA,APOE
3.091e-02	-3.48	carbohydrate derivative binding	molecular function	GO:0097367	2251	11	18094	48	BMPR1B,TNIK,HPSE2,ATP1A2,COL5A3,FGFR3,ADCY2,NTRK2,ATP13A4,APOE,PRKG1
3.138e-02	-3.46	cerebellum development	biological process	GO:0021549	103	2	18204	49	RORA,PRKG1
3.138e-02	-3.46	adenylate cyclase binding	molecular function	GO:0008179	12	1	18094	48	ADCY2
3.138e-02	-3.46	G protein-coupled neurotransmitter receptor activity	molecular function	GO:0099528	12	1	18094	48	GABRB1
3.138e-02	-3.46	inositol 1,4,5 trisphosphate binding	molecular function	GO:0070679	12	1	18094	48	ITPR2
3.147e-02	-3.46	DSG4 (desmoglein 4)	protein interactions	147409	108	2	19454	50	CSGALNACT1,SPARCL1
3.158e-02	-3.46	pleomorphic_carcinoma	COSMIC cancer mutations	pleomorphic_carcinoma	11	1	16828	49	FGFR3
3.158e-02	-3.46	skin-scalp-carcinoma-basal_cell_carcinoma	COSMIC cancer mutations	skin-scalp-carcinoma-basal_cell_carcinoma	11	1	16828	49	FGFR3
3.158e-02	-3.46	skin-neck-carcinoma-basal_cell_carcinoma	COSMIC cancer mutations	skin-neck-carcinoma-basal_cell_carcinoma	11	1	16828	49	FGFR3
3.158e-02	-3.46	congenital	COSMIC cancer mutations	congenital	11	1	16828	49	FGFR3
3.158e-02	-3.46	prostate-hyperplasia	COSMIC cancer mutations	prostate-hyperplasia	11	1	16828	49	FGFR3
3.158e-02	-3.46	skin-hand-malignant_melanoma-acral_lentiginous	COSMIC cancer mutations	skin-hand-malignant_melanoma-acral_lentiginous	11	1	16828	49	PREX2
3.158e-02	-3.46	kidney-other-oncocytoma	COSMIC cancer mutations	kidney-other-oncocytoma	11	1	16828	49	FGFR3
3.158e-02	-3.46	seborrhoeic_keratosis	COSMIC cancer mutations	seborrhoeic_keratosis	11	1	16828	49	FGFR3
3.158e-02	-3.46	skin-back-malignant_melanoma-superficial_spreading	COSMIC cancer mutations	skin-back-malignant_melanoma-superficial_spreading	11	1	16828	49	PREX2
3.158e-02	-3.46	oncocytoma	COSMIC cancer mutations	oncocytoma	11	1	16828	49	FGFR3
3.158e-02	-3.46	Composition of Lipid Particles	WikiPathways	WP3601	10	1	5310	17	APOE
3.184e-02	-3.45	mammalian oogenesis stage	biological process	GO:0022605	12	1	18204	49	BMPR1B
3.184e-02	-3.45	neurotransmitter-gated ion channel clustering	biological process	GO:0072578	12	1	18204	49	APOE
3.184e-02	-3.45	negative regulation of smooth muscle contraction	biological process	GO:0045986	12	1	18204	49	PRKG1
3.184e-02	-3.45	regulation of blood vessel remodeling	biological process	GO:0060312	12	1	18204	49	CST3
3.184e-02	-3.45	dermatan sulfate proteoglycan metabolic process	biological process	GO:0050655	12	1	18204	49	CSGALNACT1
3.184e-02	-3.45	negative regulation of collagen metabolic process	biological process	GO:0010713	12	1	18204	49	CST3
3.184e-02	-3.45	positive regulation of extrinsic apoptotic signaling pathway via death domain receptors	biological process	GO:1902043	12	1	18204	49	BMPR1B
3.184e-02	-3.45	sulfur amino acid transport	biological process	GO:0000101	12	1	18204	49	SLC1A2
3.193e-02	-3.44	MAD_homology1_Dwarfin-type	interpro domains	IPR003619	12	1	18521	50	NFIA
3.193e-02	-3.44	TGFB_receptor	interpro domains	IPR000333	12	1	18521	50	BMPR1B
3.200e-02	-3.44	CLSTN1 (calsyntenin 1)	protein interactions	22883	109	2	19454	50	MGAT4C,SLC1A3
3.204e-02	-3.44	human chr9q21.33	chromosome location	human chr9q21.33	17	1	26134	50	NTRK2
3.204e-02	-3.44	CYSTATIN	prosite domains	PS00287	9	1	12186	44	CST3
3.207e-02	-3.44	bile_duct	COSMIC cancer mutations	bile_duct	15095	48	16828	49	RBMS3,NHSL1,FBXL7,NPAS3,PRKG1,GLIS3,CST3,FGFR3,TNIK,LSAMP,NTM,APOE,ABLIM1,CTNND2,PREX2,LRP1B,CADM1,DTNA,NTRK2,FMN2,GABRB1,MGAT4C,MSI2,HPSE2,GPC5,ZBTB20,CSGALNACT1,SLC1A2,ATP1A2,GPM6A,PTPRZ1,CPE,PCDH9,CDH20,RANBP3L,ADCY2,NRG3,BMPR1B,RORA,SOX5,ATP13A4,PITPNC1,NFIA,ITPR2,SLC1A3,NRXN1,COL5A3,SPARCL1
3.207e-02	-3.44	biliary_tract-bile_duct-carcinoma-adenocarcinoma	COSMIC cancer mutations	biliary_tract-bile_duct-carcinoma-adenocarcinoma	15095	48	16828	49	NRXN1,SLC1A3,COL5A3,SPARCL1,ITPR2,PITPNC1,NFIA,SOX5,ATP13A4,NRG3,RORA,BMPR1B,RANBP3L,ADCY2,CDH20,PCDH9,CPE,ATP1A2,PTPRZ1,GPM6A,SLC1A2,CSGALNACT1,ZBTB20,GPC5,GABRB1,HPSE2,MGAT4C,MSI2,NTRK2,CADM1,DTNA,LRP1B,PREX2,FMN2,ABLIM1,CTNND2,LSAMP,TNIK,NTM,APOE,CST3,GLIS3,FGFR3,RBMS3,NHSL1,PRKG1,NPAS3,FBXL7
3.222e-02	-3.44	Carboxypeptidase-like, regulatory domain	gene3d domains	2.60.40.1120	11	1	14470	43	CPE
3.222e-02	-3.44	Heparan sulfate degradation	KEGG pathways	M00078	9	1	7161	26	HPSE2
3.222e-02	-3.44	cGMP signaling	KEGG pathways	M00694	9	1	7161	26	PRKG1
3.222e-02	-3.44	Heparan sulfate degradation	KEGG pathways	hsa_M00078	9	1	7161	26	HPSE2
3.222e-02	-3.44	cGMP signaling	KEGG pathways	hsa_M00694	9	1	7161	26	PRKG1
3.230e-02	-3.43	astrocytoma_Grade_III	COSMIC cancer mutations	astrocytoma_Grade_III	1544	9	16828	49	PRKG1,GPC5,NRG3,CADM1,LRP1B,HPSE2,FGFR3,GABRB1,ADCY2
3.249e-02	-3.43	Intracellular Signalling Through FSH Receptor and Follicle Stimulating Hormone	SMPDB pathways	SMP0000333	9	1	1369	5	ADCY2
3.249e-02	-3.43	Excitatory Neural Signalling Through 5-HTR 6 and Serotonin	SMPDB pathways	SMP0000312	9	1	1369	5	ADCY2
3.249e-02	-3.43	Excitatory Neural Signalling Through 5-HTR 4 and Serotonin	SMPDB pathways	SMP0000309	9	1	1369	5	ADCY2
3.249e-02	-3.43	Excitatory Neural Signalling Through 5-HTR 7 and Serotonin	SMPDB pathways	SMP0000311	9	1	1369	5	ADCY2
3.249e-02	-3.43	Intracellular Signalling Through Histamine H2 Receptor and Histamine	SMPDB pathways	SMP0000335	9	1	1369	5	ADCY2
3.251e-02	-3.43	cellular response to alcohol	biological process	GO:0097306	105	2	18204	49	ITPR2,ADCY2
3.253e-02	-3.43	positive regulation of cellular process	biological process	GO:0048522	5719	22	18204	49	GLIS3,FGFR3,SLC1A3,RORA,FMN2,GPM6A,CADM1,SOX5,RBMS3,SLC1A2,RANBP3L,NRXN1,NPAS3,BMPR1B,ZBTB20,NFIA,PTPRZ1,APOE,HPSE2,NTRK2,TNIK,GPC5
3.256e-02	-3.42	MH1	pfam domains	PF03165	12	1	17795	49	NFIA
3.256e-02	-3.42	CarboxypepD_reg	pfam domains	PF13620	12	1	17795	49	CPE
3.264e-02	-3.42	functioning	COSMIC cancer mutations	functioning	1803	10	16828	49	NTRK2,NRG3,PCDH9,PTPRZ1,NHSL1,FMN2,SOX5,ZBTB20,HPSE2,SLC1A2
3.264e-02	-3.42	adrenal_gland-adrenal_gland-adrenal_cortical_carcinoma-functioning	COSMIC cancer mutations	adrenal_gland-adrenal_gland-adrenal_cortical_carcinoma-functioning	1803	10	16828	49	NTRK2,PCDH9,NRG3,PTPRZ1,FMN2,NHSL1,SOX5,ZBTB20,HPSE2,SLC1A2
3.276e-02	-3.42	steroid binding	molecular function	GO:0005496	107	2	18094	48	RORA,ATP1A2
3.281e-02	-3.42	distal axon	cellular component	GO:0150034	273	3	19108	49	GPM6A,NTRK2,PCDH9
3.284e-02	-3.42	chylomicron	cellular component	GO:0042627	13	1	19108	49	APOE
3.291e-02	-3.41	PCDHA2 (protocadherin alpha 2)	protein interactions	56146	13	1	19454	50	NFIA
3.291e-02	-3.41	RNASE4 (ribonuclease A family member 4)	protein interactions	6038	13	1	19454	50	LRP1B
3.291e-02	-3.41	SPINK5 (serine peptidase inhibitor Kazal type 5)	protein interactions	11005	13	1	19454	50	CSGALNACT1
3.291e-02	-3.41	ANKH (ANKH inorganic pyrophosphate transport regulator)	protein interactions	56172	13	1	19454	50	APOE
3.291e-02	-3.41	TBCC (tubulin folding cofactor C)	protein interactions	6903	13	1	19454	50	NTM
3.291e-02	-3.41	RAB3C (RAB3C, member RAS oncogene family)	protein interactions	115827	13	1	19454	50	GPM6A
3.291e-02	-3.41	MYO16 (myosin XVI)	protein interactions	23026	13	1	19454	50	NRXN1
3.300e-02	-3.41	dermatan sulfate biosynthesis	BIOCYC pathways	META_PWY-6571	15	1	902	2	CSGALNACT1
3.302e-02	-3.41	endoplasmic reticulum	cellular component	GO:0005783	2051	10	19108	49	ITPR2,COL5A3,CST3,ATP13A4,FGFR3,SPARCL1,NRXN1,ATP1A2,APOE,FMN2
3.307e-02	-3.41	oogenesis	biological process	GO:0048477	106	2	18204	49	FMN2,BMPR1B
3.307e-02	-3.41	organ growth	biological process	GO:0035265	106	2	18204	49	FGFR3,PRKG1
3.349e-02	-3.40	phosphate-containing compound metabolic process	biological process	GO:0006796	1681	9	18204	49	NTRK2,ADCY2,RORA,FGFR3,PTPRZ1,BMPR1B,PRKG1,ATP1A2,TNIK
3.350e-02	-3.40	EGF_3	prosite domains	PS50026	196	3	12186	44	LRP1B,NRXN1,NRG3
3.363e-02	-3.39	TBR1 (T-box brain transcription factor 1)	protein interactions	10716	112	2	19454	50	NFIA,SOX5
3.374e-02	-3.39	regulation of phosphate metabolic process	biological process	GO:0019220	1154	7	18204	49	NTRK2,CADM1,FGFR3,APOE,PRKG1,ZBTB20,TNIK
3.377e-02	-3.39	FOLN	smart domains	SM00274	9	1	9717	37	SPARCL1
3.388e-02	-3.38	regulation of phosphorus metabolic process	biological process	GO:0051174	1155	7	18204	49	FGFR3,APOE,CADM1,NTRK2,TNIK,PRKG1,ZBTB20
3.389e-02	-3.38	human chr7q31.32	chromosome location	human chr7q31.32	18	1	26134	50	PTPRZ1
3.389e-02	-3.38	human chr18q21.33	chromosome location	human chr18q21.33	18	1	26134	50	CDH20
3.389e-02	-3.38	human chr4p12	chromosome location	human chr4p12	18	1	26134	50	GABRB1
3.395e-02	-3.38	transforming growth factor beta receptor activity	molecular function	GO:0005024	13	1	18094	48	BMPR1B
3.395e-02	-3.38	GABA-gated chloride ion channel activity	molecular function	GO:0022851	13	1	18094	48	GABRB1
3.395e-02	-3.38	potassium ion binding	molecular function	GO:0030955	13	1	18094	48	ATP1A2
3.400e-02	-3.38	calcium ion binding	molecular function	GO:0005509	683	5	18094	48	PCDH9,SPARCL1,LRP1B,NRXN1,ITPR2
3.440e-02	-3.37	skin-benign_melanocytic_nevus	COSMIC cancer mutations	skin-benign_melanocytic_nevus	12	1	16828	49	FGFR3
3.440e-02	-3.37	cervix-carcinoma-mixed_adenosquamous_carcinoma	COSMIC cancer mutations	cervix-carcinoma-mixed_adenosquamous_carcinoma	12	1	16828	49	FGFR3
3.440e-02	-3.37	skin-face-carcinoma-basal_cell_carcinoma	COSMIC cancer mutations	skin-face-carcinoma-basal_cell_carcinoma	12	1	16828	49	FGFR3
3.440e-02	-3.37	skin-abdomen-malignant_melanoma-nodular	COSMIC cancer mutations	skin-abdomen-malignant_melanoma-nodular	12	1	16828	49	PREX2
3.444e-02	-3.37	phospholipid efflux	biological process	GO:0033700	13	1	18204	49	APOE
3.444e-02	-3.37	cerebellar Purkinje cell differentiation	biological process	GO:0021702	13	1	18204	49	RORA
3.444e-02	-3.37	defense response to tumor cell	biological process	GO:0002357	13	1	18204	49	RBMS3
3.444e-02	-3.37	regulation of dendritic spine maintenance	biological process	GO:1902950	13	1	18204	49	APOE
3.444e-02	-3.37	glial cell fate commitment	biological process	GO:0021781	13	1	18204	49	NFIA
3.444e-02	-3.37	T-helper 17 cell differentiation	biological process	GO:0072539	13	1	18204	49	RORA
3.444e-02	-3.37	negative regulation of amyloid fibril formation	biological process	GO:1905907	13	1	18204	49	APOE
3.444e-02	-3.37	postsynaptic specialization assembly	biological process	GO:0098698	13	1	18204	49	NRXN1
3.444e-02	-3.37	ectodermal placode development	biological process	GO:0071696	13	1	18204	49	NRG3
3.444e-02	-3.37	negative regulation of cytosolic calcium ion concentration	biological process	GO:0051481	13	1	18204	49	ATP1A2
3.444e-02	-3.37	regulation of respiratory gaseous exchange by nervous system process	biological process	GO:0002087	13	1	18204	49	ATP1A2
3.444e-02	-3.37	negative regulation of homotypic cell-cell adhesion	biological process	GO:0034111	13	1	18204	49	PRKG1
3.446e-02	-3.37	FGFR3 mutant receptor activation	REACTOME pathways	R-HSA-2033514	12	1	10285	30	FGFR3
3.446e-02	-3.37	Signaling by activated point mutants of FGFR3	REACTOME pathways	R-HSA-1839130	12	1	10285	30	FGFR3
3.446e-02	-3.37	Defective EXT2 causes exostoses 2	REACTOME pathways	R-HSA-3656237	12	1	10285	30	GPC5
3.446e-02	-3.37	Defective EXT1 causes exostoses 1, TRPS2 and CHDS	REACTOME pathways	R-HSA-3656253	12	1	10285	30	GPC5
3.455e-02	-3.37	phosphotransferase activity, alcohol group as acceptor	molecular function	GO:0016773	686	5	18094	48	PRKG1,FGFR3,TNIK,BMPR1B,NTRK2
3.474e-02	-3.36	ORF3b (ORF3b protein)	protein interactions	1489670	114	2	19454	50	PCDH9,ZBTB20
3.475e-02	-3.36	Visual phototransduction	REACTOME pathways	R-HSA-2187338	101	2	10285	30	GPC5,APOE
3.500e-02	-3.35	Cadherin_CS	interpro domains	IPR020894	109	2	18521	50	CDH20,PCDH9
3.505e-02	-3.35	sulfur compound binding	molecular function	GO:1901681	271	3	18094	48	COL5A3,APOE,HPSE2
3.506e-02	-3.35	chemical homeostasis	biological process	GO:0048878	914	6	18204	49	RORA,APOE,ATP13A4,SLC1A3,ATP1A2,ZBTB20
3.518e-02	-3.35	chondroitin sulfate biosynthesis	BIOCYC pathways	HUMAN_PWY-6569	16	1	902	2	CSGALNACT1
3.522e-02	-3.35	Ldl_recept_b	pfam domains	PF00058	13	1	17795	49	LRP1B
3.525e-02	-3.35	Aldosterone synthesis and secretion	KEGG pathways	ko04925	82	2	7161	26	ADCY2,ITPR2
3.525e-02	-3.35	Aldosterone synthesis and secretion	KEGG pathways	hsa04925	82	2	7161	26	ADCY2,ITPR2
3.530e-02	-3.34	SMAD7 (SMAD family member 7)	protein interactions	4092	115	2	19454	50	SOX5,BMPR1B
3.537e-02	-3.34	protein localization to membrane	biological process	GO:0072657	462	4	18204	49	TNIK,NRXN1,APOE,CPE
3.539e-02	-3.34	chloride transmembrane transport	biological process	GO:1902476	110	2	18204	49	SLC1A3,GABRB1
3.539e-02	-3.34	positive regulation of cell junction assembly	biological process	GO:1901890	110	2	18204	49	NRXN1,NTRK2
3.540e-02	-3.34	PLXNA4 (plexin A4)	protein interactions	91584	14	1	19454	50	GPM6A
3.540e-02	-3.34	RSPO1 (R-spondin 1)	protein interactions	284654	14	1	19454	50	LRP1B
3.540e-02	-3.34	FGF7 (fibroblast growth factor 7)	protein interactions	2252	14	1	19454	50	FGFR3
3.540e-02	-3.34	Nedd4 (neural precursor cell expressed, developmentally down-regulated 4)	protein interactions	17999	14	1	19454	50	GLIS3
3.540e-02	-3.34	SLC1A2 (solute carrier family 1 member 2)	protein interactions	6506	14	1	19454	50	SLC1A2
3.540e-02	-3.34	RHEBL1 (RHEB like 1)	protein interactions	121268	14	1	19454	50	BMPR1B
3.540e-02	-3.34	SYT5 (synaptotagmin 5)	protein interactions	6861	14	1	19454	50	NRXN1
3.540e-02	-3.34	CTSO (cathepsin O)	protein interactions	1519	14	1	19454	50	CST3
3.540e-02	-3.34	DACT2 (dishevelled binding antagonist of beta catenin 2)	protein interactions	168002	14	1	19454	50	ZBTB20
3.540e-02	-3.34	IFNA8 (interferon alpha 8)	protein interactions	3445	14	1	19454	50	APOE
3.540e-02	-3.34	BOD1L2 (biorientation of chromosomes in cell division 1 like 2)	protein interactions	284257	14	1	19454	50	FMN2
3.540e-02	-3.34	C9 (complement C9)	protein interactions	735	14	1	19454	50	APOE
3.540e-02	-3.34	GAGE1 (G antigen 1)	protein interactions	2543	14	1	19454	50	PRKG1
3.554e-02	-3.34	MIR	prosite domains	PS50919	10	1	12186	44	ITPR2
3.561e-02	-3.34	regulation of membrane potential	biological process	GO:0042391	463	4	18204	49	NTRK2,GABRB1,ATP1A2,NRXN1
3.574e-02	-3.33	human chr6q24.1	chromosome location	human chr6q24.1	19	1	26134	50	NHSL1
3.574e-02	-3.33	human chr11q25	chromosome location	human chr11q25	19	1	26134	50	NTM
3.574e-02	-3.33	human chr5p15.2	chromosome location	human chr5p15.2	19	1	26134	50	CTNND2
3.603e-02	-3.32	stomach-adenocarcinoma	COSMIC cancer mutations	stomach-adenocarcinoma	4101	18	16828	49	FGFR3,SLC1A2,MGAT4C,ATP13A4,CSGALNACT1,FMN2,RORA,LRP1B,NRG3,PREX2,COL5A3,CTNND2,ABLIM1,CDH20,ITPR2,GPC5,PCDH9,ATP1A2
3.605e-02	-3.32	Intracellular Signalling Through LHCGR Receptor and Luteinizing Hormone/Choriogonadotropin	SMPDB pathways	SMP0000338	10	1	1369	5	ADCY2
3.646e-02	-3.31	skin-scalp-malignant_melanoma	COSMIC cancer mutations	skin-scalp-malignant_melanoma	634	5	16828	49	PREX2,PTPRZ1,NTM,NFIA,FMN2
3.670e-02	-3.30	import into cell	biological process	GO:0098657	687	5	18204	49	LRP1B,SLC1A2,APOE,ATP1A2,SLC1A3
3.699e-02	-3.30	VSIG8 (V-set and immunoglobulin domain containing 8)	protein interactions	391123	118	2	19454	50	CSGALNACT1,SPARCL1
3.699e-02	-3.30	CEACAM8 (CEA cell adhesion molecule 8)	protein interactions	1088	118	2	19454	50	CPE,APOE
3.702e-02	-3.30	TyrKc	smart domains	SM00219	80	2	9717	37	NTRK2,FGFR3
3.704e-02	-3.30	response to forskolin	biological process	GO:1904321	14	1	18204	49	ADCY2
3.704e-02	-3.30	negative regulation of sodium ion transmembrane transporter activity	biological process	GO:2000650	14	1	18204	49	ATP1A2
3.704e-02	-3.30	cellular response to ethanol	biological process	GO:0071361	14	1	18204	49	ITPR2
3.704e-02	-3.30	glutathione biosynthetic process	biological process	GO:0006750	14	1	18204	49	SLC1A2
3.704e-02	-3.30	negative regulation of long-term synaptic potentiation	biological process	GO:1900272	14	1	18204	49	APOE
3.704e-02	-3.30	cellular response to forskolin	biological process	GO:1904322	14	1	18204	49	ADCY2
3.704e-02	-3.30	relaxation of cardiac muscle	biological process	GO:0055119	14	1	18204	49	ATP1A2
3.704e-02	-3.30	positive regulation of phospholipid transport	biological process	GO:2001140	14	1	18204	49	APOE
3.704e-02	-3.30	sodium ion export across plasma membrane	biological process	GO:0036376	14	1	18204	49	ATP1A2
3.709e-02	-3.29	cellular homeostasis	biological process	GO:0019725	689	5	18204	49	ZBTB20,SLC1A3,ATP1A2,ATP13A4,APOE
3.715e-02	-3.29	LDLR_classB_rpt	interpro domains	IPR000033	14	1	18521	50	LRP1B
3.717e-02	-3.29	metencephalon development	biological process	GO:0022037	113	2	18204	49	PRKG1,RORA
3.721e-02	-3.29	Brenner_tumour	COSMIC cancer mutations	Brenner_tumour	13	1	16828	49	FGFR3
3.721e-02	-3.29	cervix-carcinoma-adenocarcinoma	COSMIC cancer mutations	cervix-carcinoma-adenocarcinoma	13	1	16828	49	FGFR3
3.721e-02	-3.29	endometrium-ovary-endometriosis	COSMIC cancer mutations	endometrium-ovary-endometriosis	13	1	16828	49	FGFR3
3.721e-02	-3.29	skin-scalp-malignant_melanoma-nodular	COSMIC cancer mutations	skin-scalp-malignant_melanoma-nodular	13	1	16828	49	PREX2
3.721e-02	-3.29	skin-back-carcinoma-basal_cell_carcinoma	COSMIC cancer mutations	skin-back-carcinoma-basal_cell_carcinoma	13	1	16828	49	FGFR3
3.721e-02	-3.29	skin-shoulder-malignant_melanoma-nodular	COSMIC cancer mutations	skin-shoulder-malignant_melanoma-nodular	13	1	16828	49	PREX2
3.728e-02	-3.29	FGFR3c ligand binding and activation	REACTOME pathways	R-HSA-190372	13	1	10285	30	FGFR3
3.728e-02	-3.29	CLEC7A (Dectin-1) induces NFAT activation	REACTOME pathways	R-HSA-5607763	13	1	10285	30	ITPR2
3.728e-02	-3.29	Phospholipase C-mediated cascade; FGFR3	REACTOME pathways	R-HSA-5654227	13	1	10285	30	FGFR3
3.728e-02	-3.29	FGFR3 ligand binding and activation	REACTOME pathways	R-HSA-190239	13	1	10285	30	FGFR3
3.728e-02	-3.29	GABA A receptor activation	REACTOME pathways	R-HSA-977441	13	1	10285	30	GABRB1
3.728e-02	-3.29	ERBB2 Activates PTK6 Signaling	REACTOME pathways	R-HSA-8847993	13	1	10285	30	NRG3
3.740e-02	-3.29	extracellular matrix organization	biological process	GO:0030198	274	3	18204	49	CSGALNACT1,COL5A3,HPSE2
3.745e-02	-3.28	DHFR2 (dihydrofolate reductase 2)	protein interactions	200895	287	3	19454	50	ITPR2,CPE,SLC1A3
3.745e-02	-3.28	MIR	smart domains	SM00472	10	1	9717	37	ITPR2
3.756e-02	-3.28	HLA-DPA1 (major histocompatibility complex, class II, DP alpha 1)	protein interactions	3113	119	2	19454	50	APOE,PCDH9
3.764e-02	-3.28	Insulin secretion	KEGG pathways	hsa04911	85	2	7161	26	ATP1A2,ADCY2
3.768e-02	-3.28	ATP binding	molecular function	GO:0005524	1467	8	18094	48	ATP13A4,NTRK2,BMPR1B,FGFR3,ADCY2,TNIK,PRKG1,ATP1A2
3.774e-02	-3.28	extracellular structure organization	biological process	GO:0043062	275	3	18204	49	COL5A3,CSGALNACT1,HPSE2
3.774e-02	-3.28	gliogenesis	biological process	GO:0042063	275	3	18204	49	PTPRZ1,NTRK2,NFIA
3.777e-02	-3.28	negative regulation of protein catabolic process	biological process	GO:0042177	114	2	18204	49	FMN2,CST3
3.777e-02	-3.28	negative regulation of small molecule metabolic process	biological process	GO:0062014	114	2	18204	49	PRKG1,APOE
3.777e-02	-3.28	regulation of circadian rhythm	biological process	GO:0042752	114	2	18204	49	RORA,PRKG1
3.777e-02	-3.28	VASP (vasodilator stimulated phosphoprotein)	protein interactions	7408	288	3	19454	50	FMN2,NHSL1,PRKG1
3.779e-02	-3.28	Bone Morphogenic Protein (BMP) Signalling and Regulation	WikiPathways	WP1425	12	1	5310	17	BMPR1B
3.780e-02	-3.28	axolemma	cellular component	GO:0030673	15	1	19108	49	SLC1A2
3.780e-02	-3.28	low-density lipoprotein particle	cellular component	GO:0034362	15	1	19108	49	APOE
3.788e-02	-3.27	NPR1 (natriuretic peptide receptor 1)	protein interactions	4881	15	1	19454	50	PRKG1
3.788e-02	-3.27	PCSK1N (proprotein convertase subtilisin/kexin type 1 inhibitor)	protein interactions	27344	15	1	19454	50	MGAT4C
3.788e-02	-3.27	DEFB123 (defensin beta 123)	protein interactions	245936	15	1	19454	50	LRP1B
3.788e-02	-3.27	TESPA1 (thymocyte expressed, positive selection associated 1)	protein interactions	9840	15	1	19454	50	ITPR2
3.788e-02	-3.27	TIAM2 (TIAM Rac1 associated GEF 2)	protein interactions	26230	15	1	19454	50	TNIK
3.788e-02	-3.27	RNASE13 (ribonuclease A family member 13 (inactive))	protein interactions	440163	15	1	19454	50	CPE
3.788e-02	-3.27	OLFM3 (olfactomedin 3)	protein interactions	118427	15	1	19454	50	LRP1B
3.788e-02	-3.27	IGSF1 (immunoglobulin superfamily member 1)	protein interactions	3547	15	1	19454	50	BMPR1B
3.788e-02	-3.27	FGF9 (fibroblast growth factor 9)	protein interactions	2254	15	1	19454	50	FGFR3
3.798e-02	-3.27	Cadherin-like_dom	interpro domains	IPR002126	114	2	18521	50	CDH20,PCDH9
3.806e-02	-3.27	positive regulation of MAPK cascade	biological process	GO:0043410	473	4	18204	49	FGFR3,TNIK,APOE,NTRK2
3.808e-02	-3.27	external encapsulating structure organization	biological process	GO:0045229	276	3	18204	49	COL5A3,CSGALNACT1,HPSE2
3.811e-02	-3.27	Cadherin	pfam domains	PF00028	112	2	17795	49	CDH20,PCDH9
3.819e-02	-3.27	membrane raft	cellular component	GO:0045121	290	3	19108	49	SLC1A2,ATP1A2,ADCY2
3.848e-02	-3.26	VEGFR2 mediated cell proliferation	REACTOME pathways	R-HSA-5218921	258	3	10285	30	FGFR3,NRG3,ITPR2
3.855e-02	-3.26	solute:monoatomic cation symporter activity	molecular function	GO:0015294	117	2	18094	48	SLC1A2,SLC1A3
3.855e-02	-3.26	calcium channel activity	molecular function	GO:0005262	117	2	18094	48	GPM6A,ITPR2
3.861e-02	-3.25	Transport of inorganic cations/anions and amino acids/oligopeptides	REACTOME pathways	R-HSA-425393	107	2	10285	30	SLC1A3,SLC1A2
3.878e-02	-3.25	regulation of GTPase activity	biological process	GO:0043087	278	3	18204	49	PREX2,NTRK2,PRKG1
3.885e-02	-3.25	membrane microdomain	cellular component	GO:0098857	292	3	19108	49	ADCY2,ATP1A2,SLC1A2
3.900e-02	-3.24	germ_cell_tumour	COSMIC cancer mutations	germ_cell_tumour	867	6	16828	49	NTRK2,PREX2,TNIK,FGFR3,PRKG1,BMPR1B
3.902e-02	-3.24	RANBD1	prosite domains	PS50196	11	1	12186	44	RANBP3L
3.902e-02	-3.24	RECEPTOR_TYR_KIN_II	prosite domains	PS00239	11	1	12186	44	NTRK2
3.902e-02	-3.24	NC1_FIB	prosite domains	PS51461	11	1	12186	44	COL5A3
3.908e-02	-3.24	phosphatidylglycerol binding	molecular function	GO:1901611	15	1	18094	48	PITPNC1
3.908e-02	-3.24	neurexin family protein binding	molecular function	GO:0042043	15	1	18094	48	CPE
3.908e-02	-3.24	low-density lipoprotein particle receptor activity	molecular function	GO:0005041	15	1	18094	48	LRP1B
3.914e-02	-3.24	skin-leg-malignant_melanoma-nodular	COSMIC cancer mutations	skin-leg-malignant_melanoma-nodular	258	3	16828	49	PTPRZ1,ATP13A4,FMN2
3.920e-02	-3.24	Cadherin-like_sf	interpro domains	IPR015919	116	2	18521	50	CDH20,PCDH9
3.930e-02	-3.24	BRK1 (BRICK1 subunit of SCAR/WAVE actin nucleating complex)	protein interactions	55845	122	2	19454	50	NHSL1,DTNA
3.943e-02	-3.23	human chr13q31.3	chromosome location	human chr13q31.3	21	1	26134	50	GPC5
3.943e-02	-3.23	human chr4q32.3	chromosome location	human chr4q32.3	21	1	26134	50	CPE
3.943e-02	-3.23	human chr10q23.1	chromosome location	human chr10q23.1	21	1	26134	50	NRG3
3.948e-02	-3.23	glycoprotein biosynthetic process	biological process	GO:0009101	280	3	18204	49	MGAT4C,CSGALNACT1,BMPR1B
3.953e-02	-3.23	chondroitin sulfate biosynthesis	BIOCYC pathways	META_PWY-6569	18	1	902	2	CSGALNACT1
3.959e-02	-3.23	regulation of synapse assembly	biological process	GO:0051963	117	2	18204	49	NRXN1,NTRK2
3.959e-02	-3.23	NAD+ Signalling and Aging	SMPDB pathways	SMP0084271	11	1	1369	5	RORA
3.963e-02	-3.23	lung-carcinoma-squamous_cell_carcinoma	COSMIC cancer mutations	lung-carcinoma-squamous_cell_carcinoma	14664	47	16828	49	FGFR3,GLIS3,NKAIN3,NHSL1,NPAS3,PRKG1,FBXL7,CTNND2,ABLIM1,APOE,TNIK,LSAMP,NTM,MGAT4C,MSI2,HPSE2,GABRB1,FMN2,PREX2,NTRK2,DTNA,LRP1B,CADM1,ZBTB20,GPC5,SLC1A2,CSGALNACT1,CDH20,RANBP3L,ADCY2,ATP1A2,GPM6A,PTPRZ1,PCDH9,CPE,ATP13A4,SOX5,BMPR1B,RORA,NRG3,COL5A3,SPARCL1,SLC1A3,NRXN1,PITPNC1,NFIA,ITPR2
3.964e-02	-3.23	system process	biological process	GO:0003008	2015	10	18204	49	SLC1A2,PRKG1,PTPRZ1,ATP1A2,NRXN1,ABLIM1,NTRK2,SLC1A3,DTNA,APOE
3.964e-02	-3.23	negative regulation of sodium ion transmembrane transport	biological process	GO:1902306	15	1	18204	49	ATP1A2
3.964e-02	-3.23	positive regulation of cholesterol metabolic process	biological process	GO:0090205	15	1	18204	49	APOE
3.964e-02	-3.23	synapse maturation	biological process	GO:0060074	15	1	18204	49	NFIA
3.964e-02	-3.23	regulation of phospholipid transport	biological process	GO:2001138	15	1	18204	49	APOE
3.964e-02	-3.23	peripheral nervous system neuron differentiation	biological process	GO:0048934	15	1	18204	49	NTRK2
3.964e-02	-3.23	neuroblast division	biological process	GO:0055057	15	1	18204	49	SOX5
3.964e-02	-3.23	regulation of inositol phosphate biosynthetic process	biological process	GO:0010919	15	1	18204	49	PRKG1
3.964e-02	-3.23	protein homotrimerization	biological process	GO:0070207	15	1	18204	49	SLC1A2
3.964e-02	-3.23	lipoprotein catabolic process	biological process	GO:0042159	15	1	18204	49	APOE
3.964e-02	-3.23	peripheral nervous system neuron development	biological process	GO:0048935	15	1	18204	49	NTRK2
3.964e-02	-3.23	exit from mitosis	biological process	GO:0010458	15	1	18204	49	NFIA
3.964e-02	-3.23	cerebellar Purkinje cell layer formation	biological process	GO:0021694	15	1	18204	49	RORA
3.964e-02	-3.23	intracellular potassium ion homeostasis	biological process	GO:0030007	15	1	18204	49	ATP1A2
3.964e-02	-3.23	chondrocyte proliferation	biological process	GO:0035988	15	1	18204	49	FGFR3
3.964e-02	-3.23	collateral sprouting	biological process	GO:0048668	15	1	18204	49	PRKG1
3.964e-02	-3.23	negative regulation of amino acid transport	biological process	GO:0051956	15	1	18204	49	PRKG1
3.970e-02	-3.23	bone-tibia-Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour	COSMIC cancer mutations	bone-tibia-Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour	649	5	16828	49	PRKG1,FGFR3,PREX2,TNIK,ABLIM1
3.975e-02	-3.23	FH2_Formin	interpro domains	IPR015425	15	1	18521	50	FMN2
3.975e-02	-3.23	CNH_dom	interpro domains	IPR001180	15	1	18521	50	TNIK
3.975e-02	-3.23	FH2_Formin_sf	interpro domains	IPR042201	15	1	18521	50	FMN2
3.975e-02	-3.23	ATPase_P-typ_cation-transptr_C	interpro domains	IPR006068	15	1	18521	50	ATP1A2
4.002e-02	-3.22	endometriosis	COSMIC cancer mutations	endometriosis	14	1	16828	49	FGFR3
4.002e-02	-3.22	small_round_cell_tumour	COSMIC cancer mutations	small_round_cell_tumour	14	1	16828	49	FGFR3
4.002e-02	-3.22	in_situ_neoplasm	COSMIC cancer mutations	in_situ_neoplasm	14	1	16828	49	FGFR3
4.002e-02	-3.22	urinary_tract-renal_pelvis-carcinoma-transitional_cell_carcinoma	COSMIC cancer mutations	urinary_tract-renal_pelvis-carcinoma-transitional_cell_carcinoma	14	1	16828	49	FGFR3
4.002e-02	-3.22	soft_tissue-small_round_cell_tumour	COSMIC cancer mutations	soft_tissue-small_round_cell_tumour	14	1	16828	49	FGFR3
4.009e-02	-3.22	GABAergic synapse	KEGG pathways	hsa04727	88	2	7161	26	GABRB1,ADCY2
4.009e-02	-3.22	GABAergic synapse	KEGG pathways	ko04727	88	2	7161	26	GABRB1,ADCY2
4.010e-02	-3.22	SHC1 events in ERBB4 signaling	REACTOME pathways	R-HSA-1250347	14	1	10285	30	NRG3
4.010e-02	-3.22	DCC mediated attractive signaling	REACTOME pathways	R-HSA-418885	14	1	10285	30	ABLIM1
4.010e-02	-3.22	Synthesis of PE	REACTOME pathways	R-HSA-1483213	14	1	10285	30	ETNPPL
4.022e-02	-3.21	ErbB receptor signaling network	Pathway Interaction DB	erbb_network_pathway	13	1	2226	7	NRG3
4.027e-02	-3.21	postsynaptic density, intracellular component	cellular component	GO:0099092	16	1	19108	49	TNIK
4.035e-02	-3.21	SYTL2 (synaptotagmin like 2)	protein interactions	54843	16	1	19454	50	NRXN1
4.035e-02	-3.21	SYT4 (synaptotagmin 4)	protein interactions	6860	16	1	19454	50	NRXN1
4.035e-02	-3.21	Sumo3 (small ubiquitin-like modifier 3)	protein interactions	20610	16	1	19454	50	ITPR2
4.035e-02	-3.21	CTSK (cathepsin K)	protein interactions	1513	16	1	19454	50	FGFR3
4.035e-02	-3.21	CNTNAP2 (contactin associated protein 2)	protein interactions	26047	16	1	19454	50	CPE
4.035e-02	-3.21	FNDC8 (fibronectin type III domain containing 8)	protein interactions	54752	16	1	19454	50	SPARCL1
4.035e-02	-3.21	HLA-H (major histocompatibility complex, class I, H (pseudogene))	protein interactions	3136	16	1	19454	50	FGFR3
4.035e-02	-3.21	GALNT13 (polypeptide N-acetylgalactosaminyltransferase 13)	protein interactions	114805	16	1	19454	50	TNIK
4.035e-02	-3.21	SYT9 (synaptotagmin 9)	protein interactions	143425	16	1	19454	50	NRXN1
4.035e-02	-3.21	CYP2C8 (cytochrome P450 family 2 subfamily C member 8)	protein interactions	1558	16	1	19454	50	APOE
4.035e-02	-3.21	TWIST2 (twist family bHLH transcription factor 2)	protein interactions	117581	16	1	19454	50	ZBTB20
4.035e-02	-3.21	GABRR1 (gamma-aminobutyric acid type A receptor subunit rho1)	protein interactions	2569	16	1	19454	50	PRKG1
4.053e-02	-3.21	CNH	pfam domains	PF00780	15	1	17795	49	TNIK
4.053e-02	-3.21	FH2	pfam domains	PF02181	15	1	17795	49	FMN2
4.053e-02	-3.21	Cation_ATPase_C	pfam domains	PF00689	15	1	17795	49	ATP1A2
4.054e-02	-3.21	Wnt signaling pathway	biological process	GO:0016055	283	3	18204	49	CPE,TNIK,CTNND2
4.092e-02	-3.20	regulation of signaling	biological process	GO:0023051	3534	15	18204	49	PREX2,CADM1,FGFR3,SLC1A3,RORA,RBMS3,NTRK2,APOE,CTNND2,BMPR1B,TNIK,NRXN1,NRG3,ATP1A2,GPC5
4.093e-02	-3.20	Protein digestion and absorption	KEGG pathways	ko04974	89	2	7161	26	ATP1A2,COL5A3
4.093e-02	-3.20	Protein digestion and absorption	KEGG pathways	hsa04974	89	2	7161	26	ATP1A2,COL5A3
4.106e-02	-3.19	SCGB1D1 (secretoglobin family 1D member 1)	protein interactions	10648	125	2	19454	50	CPE,LRP1B
4.112e-02	-3.19	RanBD	smart domains	SM00160	11	1	9717	37	RANBP3L
4.112e-02	-3.19	COLFI	smart domains	SM00038	11	1	9717	37	COL5A3
4.112e-02	-3.19	export from cell	biological process	GO:0140352	485	4	18204	49	ATP1A2,NRXN1,CPE,NTRK2
4.120e-02	-3.19	Neural Crest Differentiation	WikiPathways	WP2064	102	2	5310	17	SOX5,FGFR3
4.126e-02	-3.19	Integration of energy metabolism	REACTOME pathways	R-HSA-163685	111	2	10285	30	ADCY2,ITPR2
4.144e-02	-3.18	striated muscle contraction	biological process	GO:0006941	120	2	18204	49	ATP1A2,DTNA
4.145e-02	-3.18	skin-acral-malignant_melanoma	COSMIC cancer mutations	skin-acral-malignant_melanoma	264	3	16828	49	COL5A3,FMN2,CDH20
4.146e-02	-3.18	upper_leg	COSMIC cancer mutations	upper_leg	880	6	16828	49	PCDH9,PREX2,GLIS3,FGFR3,FMN2,NFIA
4.156e-02	-3.18	regulation of cell communication	biological process	GO:0010646	3541	15	18204	49	SLC1A3,FGFR3,RORA,CADM1,PREX2,RBMS3,APOE,NTRK2,ATP1A2,NRG3,TNIK,NRXN1,GPC5,BMPR1B,CTNND2
4.163e-02	-3.18	adenylate cyclase activity	molecular function	GO:0004016	16	1	18094	48	ADCY2
4.163e-02	-3.18	oxysterol binding	molecular function	GO:0008142	16	1	18094	48	RORA
4.163e-02	-3.18	ligand-gated monoatomic ion channel activity involved in regulation of presynaptic membrane potential	molecular function	GO:0099507	16	1	18094	48	GABRB1
4.163e-02	-3.18	cGMP binding	molecular function	GO:0030553	16	1	18094	48	PRKG1
4.166e-02	-3.18	SYP (synaptophysin)	protein interactions	6855	126	2	19454	50	GPM6A,PITPNC1
4.198e-02	-3.17	ossification	biological process	GO:0001503	287	3	18204	49	CSGALNACT1,FGFR3,BMPR1B
4.207e-02	-3.17	chloride transport	biological process	GO:0006821	121	2	18204	49	GABRB1,SLC1A3
4.223e-02	-3.16	insulin metabolic process	biological process	GO:1901142	16	1	18204	49	CPE
4.223e-02	-3.16	neuron cell-cell adhesion	biological process	GO:0007158	16	1	18204	49	NRXN1
4.223e-02	-3.16	low-density lipoprotein particle remodeling	biological process	GO:0034374	16	1	18204	49	APOE
4.223e-02	-3.16	non-proteinogenic amino acid biosynthetic process	biological process	GO:0170043	16	1	18204	49	SLC1A3
4.223e-02	-3.16	regulation of amino acid transmembrane transport	biological process	GO:1903789	16	1	18204	49	ATP1A2
4.223e-02	-3.16	regulation of amino acid import across plasma membrane	biological process	GO:0010958	16	1	18204	49	ATP1A2
4.223e-02	-3.16	regulation of respiratory system process	biological process	GO:0044065	16	1	18204	49	ATP1A2
4.223e-02	-3.16	nonribosomal peptide biosynthetic process	biological process	GO:0019184	16	1	18204	49	SLC1A2
4.223e-02	-3.16	asymmetric cell division	biological process	GO:0008356	16	1	18204	49	SOX5
4.223e-02	-3.16	positive regulation of membrane protein ectodomain proteolysis	biological process	GO:0051044	16	1	18204	49	APOE
4.223e-02	-3.16	cardiac left ventricle morphogenesis	biological process	GO:0003214	16	1	18204	49	CPE
4.226e-02	-3.16	EPB41L4A (erythrocyte membrane protein band 4.1 like 4A)	protein interactions	64097	127	2	19454	50	ABLIM1,DTNA
4.235e-02	-3.16	cNMP-bd_CS	interpro domains	IPR018488	16	1	18521	50	PRKG1
4.235e-02	-3.16	CarboxyPept-like_regulatory	interpro domains	IPR008969	16	1	18521	50	CPE
4.242e-02	-3.16	inorganic ion transmembrane transport	biological process	GO:0098660	715	5	18204	49	ATP1A2,SLC1A3,GABRB1,GPM6A,ITPR2
4.250e-02	-3.16	CNMP_BINDING_2	prosite domains	PS00889	12	1	12186	44	PRKG1
4.250e-02	-3.16	lung-middle_lobe-carcinoma-adenocarcinoma	COSMIC cancer mutations	lung-middle_lobe-carcinoma-adenocarcinoma	1368	8	16828	49	ATP1A2,PCDH9,CPE,LRP1B,ITPR2,CTNND2,ATP13A4,HPSE2
4.261e-02	-3.16	Morphine addiction	KEGG pathways	hsa05032	91	2	7161	26	ADCY2,GABRB1
4.261e-02	-3.16	Morphine addiction	KEGG pathways	ko05032	91	2	7161	26	GABRB1,ADCY2
4.267e-02	-3.15	neuron projection terminus	cellular component	GO:0044306	128	2	19108	49	NTRK2,SLC1A2
4.282e-02	-3.15	ureter	COSMIC cancer mutations	ureter	15	1	16828	49	FGFR3
4.282e-02	-3.15	PAX4 (paired box 4)	protein interactions	5078	17	1	19454	50	NTM
4.282e-02	-3.15	TAGAP (T cell activation RhoGTPase activating protein)	protein interactions	117289	17	1	19454	50	DTNA
4.282e-02	-3.15	C16orf92 (chromosome 16 open reading frame 92)	protein interactions	146378	17	1	19454	50	APOE
4.282e-02	-3.15	RASL12 (RAS like family 12)	protein interactions	51285	17	1	19454	50	BMPR1B
4.282e-02	-3.15	SEPSECS (Sep (O-phosphoserine) tRNA:Sec (selenocysteine) tRNA synthase)	protein interactions	51091	17	1	19454	50	ABLIM1
4.282e-02	-3.15	DPP6 (dipeptidyl peptidase like 6)	protein interactions	1804	17	1	19454	50	GPM6A
4.282e-02	-3.15	Shcbp1 (Shc SH2-domain binding protein 1)	protein interactions	20419	17	1	19454	50	GPC5
4.282e-02	-3.15	Sqstm1 (sequestosome 1)	protein interactions	18412	17	1	19454	50	BMPR1B
4.282e-02	-3.15	MSANTD2 (Myb/SANT DNA binding domain containing 2)	protein interactions	79684	17	1	19454	50	SOX5
4.286e-02	-3.15	ARFGEF2 (ADP ribosylation factor guanine nucleotide exchange factor 2)	protein interactions	10564	128	2	19454	50	GABRB1,CSGALNACT1
4.286e-02	-3.15	ATF7IP (activating transcription factor 7 interacting protein)	protein interactions	55729	128	2	19454	50	SOX5,CADM1
4.290e-02	-3.15	N-Glycan antennae elongation	REACTOME pathways	R-HSA-975577	15	1	10285	30	MGAT4C
4.290e-02	-3.15	Inhibition of adenylate cyclase pathway	REACTOME pathways	R-HSA-997269	15	1	10285	30	ADCY2
4.290e-02	-3.15	Adenylate cyclase inhibitory pathway	REACTOME pathways	R-HSA-170670	15	1	10285	30	ADCY2
4.290e-02	-3.15	ERBB2 Regulates Cell Motility	REACTOME pathways	R-HSA-6785631	15	1	10285	30	NRG3
4.302e-02	-3.15	acral	COSMIC cancer mutations	acral	268	3	16828	49	FMN2,COL5A3,CDH20
4.311e-02	-3.14	human chr5p15.31	chromosome location	human chr5p15.31	23	1	26134	50	ADCY2
4.313e-02	-3.14	Lactose Intolerance	SMPDB pathways	SMP0000458	12	1	1369	5	ATP1A2
4.313e-02	-3.14	Lactose Degradation	SMPDB pathways	SMP0000457	12	1	1369	5	ATP1A2
4.346e-02	-3.14	GnRH signaling pathway	KEGG pathways	ko04912	92	2	7161	26	ITPR2,ADCY2
4.346e-02	-3.14	GnRH signaling pathway	KEGG pathways	hsa04912	92	2	7161	26	ADCY2,ITPR2
4.346e-02	-3.14	POLA2 (DNA polymerase alpha 2, accessory subunit)	protein interactions	23649	129	2	19454	50	FGFR3,CPE
4.346e-02	-3.14	CHD7 (chromodomain helicase DNA binding protein 7)	protein interactions	55636	129	2	19454	50	ZBTB20,SOX5
4.368e-02	-3.13	Formin, FH2 domain	gene3d domains	1.20.58.2220	15	1	14470	43	FMN2
4.381e-02	-3.13	response to hypoxia	biological process	GO:0001666	292	3	18204	49	ITPR2,RORA,FMN2
4.395e-02	-3.12	ERK Pathway in Huntington's Disease	WikiPathways	WP3853	14	1	5310	17	NTRK2
4.397e-02	-3.12	action potential	biological process	GO:0001508	124	2	18204	49	NTRK2,ATP1A2
4.397e-02	-3.12	positive regulation of lipid metabolic process	biological process	GO:0045834	124	2	18204	49	ZBTB20,APOE
4.417e-02	-3.12	transmembrane receptor protein phosphatase activity	molecular function	GO:0019198	17	1	18094	48	PTPRZ1
4.417e-02	-3.12	transmembrane receptor protein tyrosine phosphatase activity	molecular function	GO:0005001	17	1	18094	48	PTPRZ1
4.468e-02	-3.11	TRPS1 (transcriptional repressor GATA binding 1)	protein interactions	7227	131	2	19454	50	SOX5,NFIA
4.468e-02	-3.11	ZNF609 (zinc finger protein 609)	protein interactions	23060	131	2	19454	50	SOX5,NFIA
4.468e-02	-3.11	NCOA2 (nuclear receptor coactivator 2)	protein interactions	10499	131	2	19454	50	NFIA,RORA
4.477e-02	-3.11	DWA	smart domains	SM00523	12	1	9717	37	NFIA
4.481e-02	-3.11	regulation of hydrolase activity	biological process	GO:0051336	726	5	18204	49	PRKG1,PREX2,NTRK2,CST3,FGFR3
4.481e-02	-3.11	protein trimerization	biological process	GO:0070206	17	1	18204	49	SLC1A2
4.481e-02	-3.11	ureter development	biological process	GO:0072189	17	1	18204	49	NFIA
4.481e-02	-3.11	membrane depolarization during cardiac muscle cell action potential	biological process	GO:0086012	17	1	18204	49	ATP1A2
4.481e-02	-3.11	cGMP metabolic process	biological process	GO:0046068	17	1	18204	49	RORA
4.481e-02	-3.11	cell communication by electrical coupling involved in cardiac conduction	biological process	GO:0086064	17	1	18204	49	ATP1A2
4.481e-02	-3.11	T cell mediated cytotoxicity	biological process	GO:0001913	17	1	18204	49	CADM1
4.481e-02	-3.11	viral genome replication	biological process	GO:0019079	17	1	18204	49	NFIA
4.481e-02	-3.11	reverse cholesterol transport	biological process	GO:0043691	17	1	18204	49	APOE
4.481e-02	-3.11	fatty acid homeostasis	biological process	GO:0055089	17	1	18204	49	APOE
4.481e-02	-3.11	negative regulation of triglyceride metabolic process	biological process	GO:0090209	17	1	18204	49	APOE
4.481e-02	-3.11	microvillus assembly	biological process	GO:0030033	17	1	18204	49	TNIK
4.481e-02	-3.11	heparin metabolic process	biological process	GO:0030202	17	1	18204	49	CSGALNACT1
4.481e-02	-3.11	positive regulation of vascular permeability	biological process	GO:0043117	17	1	18204	49	APOE
4.481e-02	-3.11	retinal rod cell differentiation	biological process	GO:0060221	17	1	18204	49	NTRK2
4.481e-02	-3.11	high-density lipoprotein particle remodeling	biological process	GO:0034375	17	1	18204	49	APOE
4.481e-02	-3.11	regulation of amyloid fibril formation	biological process	GO:1905906	17	1	18204	49	APOE
4.481e-02	-3.11	T-helper 17 type immune response	biological process	GO:0072538	17	1	18204	49	RORA
4.493e-02	-3.10	regulation of ERK1 and ERK2 cascade	biological process	GO:0070372	295	3	18204	49	NTRK2,APOE,FGFR3
4.493e-02	-3.10	CA_dom	interpro domains	IPR001148	17	1	18521	50	PTPRZ1
4.493e-02	-3.10	CA_dom_sf	interpro domains	IPR036398	17	1	18521	50	PTPRZ1
4.493e-02	-3.10	Cystatin_dom	interpro domains	IPR000010	17	1	18521	50	CST3
4.493e-02	-3.10	A/G_cyclase_CS	interpro domains	IPR018297	17	1	18521	50	ADCY2
4.506e-02	-3.10	Cadherins	gene3d domains	2.60.40.60	114	2	14470	43	PCDH9,CDH20
4.507e-02	-3.10	ductal_carcinoma	COSMIC cancer mutations	ductal_carcinoma	15798	49	16828	49	BMPR1B,RORA,NRG3,ATP13A4,SOX5,ITPR2,NFIA,PITPNC1,SPARCL1,COL5A3,NRXN1,SLC1A3,CSGALNACT1,SLC1A2,CPE,PCDH9,PTPRZ1,GPM6A,ATP1A2,ADCY2,RANBP3L,CDH20,FMN2,CADM1,NTRK2,DTNA,LRP1B,PREX2,HPSE2,MGAT4C,MSI2,GABRB1,GPC5,ZBTB20,PRKG1,NPAS3,FBXL7,NHSL1,RBMS3,FGFR3,CST3,NKAIN3,GLIS3,APOE,NTM,LSAMP,TNIK,CTNND2,ABLIM1
4.517e-02	-3.10	PROTEIN_KINASE_TYR	prosite domains	PS00109	94	2	12186	44	NTRK2,FGFR3
4.525e-02	-3.10	kinase activity	molecular function	GO:0016301	739	5	18094	48	FGFR3,TNIK,PRKG1,BMPR1B,NTRK2
4.529e-02	-3.09	NKIRAS1 (NFKB inhibitor interacting Ras like 1)	protein interactions	28512	18	1	19454	50	BMPR1B
4.529e-02	-3.09	Tgfbr1 (transforming growth factor, beta receptor I)	protein interactions	21812	18	1	19454	50	BMPR1B
4.529e-02	-3.09	ZNF224 (zinc finger protein 224)	protein interactions	7767	18	1	19454	50	LRP1B
4.529e-02	-3.09	NECTIN1 (nectin cell adhesion molecule 1)	protein interactions	5818	18	1	19454	50	FGFR3
4.529e-02	-3.09	OPCML (opioid binding protein/cell adhesion molecule like)	protein interactions	4978	18	1	19454	50	NTM
4.529e-02	-3.09	KLHL1 (kelch like family member 1)	protein interactions	57626	18	1	19454	50	BMPR1B
4.529e-02	-3.09	SELL (selectin L)	protein interactions	6402	18	1	19454	50	PRKG1
4.529e-02	-3.09	Lck (lymphocyte protein tyrosine kinase)	protein interactions	16818	18	1	19454	50	APOE
4.530e-02	-3.09	GPIHBP1 (glycosylphosphatidylinositol anchored high density lipoprotein binding protein 1)	protein interactions	338328	132	2	19454	50	CPE,FGFR3
4.531e-02	-3.09	positive regulation of nervous system development	biological process	GO:0051962	296	3	18204	49	NTRK2,PTPRZ1,NRXN1
4.547e-02	-3.09	phosphorylation	biological process	GO:0016310	729	5	18204	49	TNIK,FGFR3,NTRK2,PRKG1,BMPR1B
4.561e-02	-3.09	flank	COSMIC cancer mutations	flank	16	1	16828	49	FGFR3
4.561e-02	-3.09	renal_pelvis	COSMIC cancer mutations	renal_pelvis	16	1	16828	49	FGFR3
4.561e-02	-3.09	normal	COSMIC cancer mutations	normal	16	1	16828	49	FGFR3
4.561e-02	-3.09	urinary_tract-carcinoma	COSMIC cancer mutations	urinary_tract-carcinoma	16	1	16828	49	FGFR3
4.569e-02	-3.09	muscle system process	biological process	GO:0003012	297	3	18204	49	PRKG1,DTNA,ATP1A2
4.570e-02	-3.09	Rap1 signalling	REACTOME pathways	R-HSA-392517	16	1	10285	30	PRKG1
4.570e-02	-3.09	PI3K events in ERBB2 signaling	REACTOME pathways	R-HSA-1963642	16	1	10285	30	NRG3
4.570e-02	-3.09	PKA activation	REACTOME pathways	R-HSA-163615	16	1	10285	30	ADCY2
4.570e-02	-3.09	GRB2 events in ERBB2 signaling	REACTOME pathways	R-HSA-1963640	16	1	10285	30	NRG3
4.573e-02	-3.08	carbohydrate derivative metabolic process	biological process	GO:1901135	975	6	18204	49	ADCY2,RORA,CSGALNACT1,BMPR1B,ATP1A2,MGAT4C
4.581e-02	-3.08	ZZ	pfam domains	PF00569	17	1	17795	49	DTNA
4.581e-02	-3.08	Cystatin	pfam domains	PF00031	17	1	17795	49	CST3
4.581e-02	-3.08	Carb_anhydrase	pfam domains	PF00194	17	1	17795	49	PTPRZ1
4.590e-02	-3.08	response to amino acid	biological process	GO:0043200	127	2	18204	49	NTRK2,SLC1A2
4.596e-02	-3.08	LDLRB	prosite domains	PS51120	13	1	12186	44	LRP1B
4.596e-02	-3.08	CARBOXYPEPT_ZN_2	prosite domains	PS00133	13	1	12186	44	CPE
4.596e-02	-3.08	CARBOXYPEPT_ZN_1	prosite domains	PS00132	13	1	12186	44	CPE
4.597e-02	-3.08	protein phosphorylation	biological process	GO:0006468	503	4	18204	49	PRKG1,BMPR1B,NTRK2,TNIK
4.621e-02	-3.07	adenyl ribonucleotide binding	molecular function	GO:0032559	1528	8	18094	48	TNIK,PRKG1,ATP1A2,ATP13A4,NTRK2,BMPR1B,FGFR3,ADCY2
4.629e-02	-3.07	LPA4-mediated signaling events	Pathway Interaction DB	lpa4_pathway	15	1	2226	7	ADCY2
4.652e-02	-3.07	monoatomic cation homeostasis	biological process	GO:0055080	505	4	18204	49	APOE,ATP13A4,SLC1A3,ATP1A2
4.652e-02	-3.07	cellular response to organonitrogen compound	biological process	GO:0071417	505	4	18204	49	GABRB1,SLC1A3,ITPR2,SLC1A2
4.665e-02	-3.07	Trehalose Degradation	SMPDB pathways	SMP0000467	13	1	1369	5	ATP1A2
4.671e-02	-3.06	GABA receptor binding	molecular function	GO:0050811	18	1	18094	48	GABRB1
4.671e-02	-3.06	intracellularly gated calcium channel activity	molecular function	GO:0015278	18	1	18094	48	ITPR2
4.671e-02	-3.06	phosphatidylcholine transporter activity	molecular function	GO:0008525	18	1	18094	48	PITPNC1
4.671e-02	-3.06	lipoprotein particle receptor activity	molecular function	GO:0030228	18	1	18094	48	LRP1B
4.671e-02	-3.06	transmembrane receptor protein tyrosine kinase activator activity	molecular function	GO:0030297	18	1	18094	48	NRG3
4.693e-02	-3.06	Circadian entrainment	KEGG pathways	hsa04713	96	2	7161	26	PRKG1,ADCY2
4.693e-02	-3.06	Circadian entrainment	KEGG pathways	ko04713	96	2	7161	26	PRKG1,ADCY2
4.716e-02	-3.05	FOXP1 (forkhead box P1)	protein interactions	27086	135	2	19454	50	NFIA,SOX5
4.716e-02	-3.05	Myo1c (myosin IC)	protein interactions	17913	135	2	19454	50	ABLIM1,ITPR2
4.722e-02	-3.05	central_nervous_system-brain-glioma-astrocytoma_Grade_IV	COSMIC cancer mutations	central_nervous_system-brain-glioma-astrocytoma_Grade_IV	15813	49	16828	49	PITPNC1,NFIA,ITPR2,COL5A3,SPARCL1,SLC1A3,NRXN1,RORA,BMPR1B,NRG3,ATP13A4,SOX5,ATP1A2,GPM6A,PTPRZ1,CPE,PCDH9,CDH20,RANBP3L,ADCY2,CSGALNACT1,SLC1A2,GPC5,ZBTB20,FMN2,PREX2,NTRK2,DTNA,LRP1B,CADM1,MGAT4C,MSI2,HPSE2,GABRB1,APOE,TNIK,LSAMP,NTM,CTNND2,ABLIM1,NHSL1,FBXL7,PRKG1,NPAS3,RBMS3,FGFR3,GLIS3,NKAIN3,CST3
4.738e-02	-3.05	negative regulation of sodium ion transport	biological process	GO:0010766	18	1	18204	49	ATP1A2
4.738e-02	-3.05	regulation of extracellular matrix disassembly	biological process	GO:0010715	18	1	18204	49	CST3
4.738e-02	-3.05	negative regulation of anoikis	biological process	GO:2000811	18	1	18204	49	NTRK2
4.738e-02	-3.05	dendritic spine morphogenesis	biological process	GO:0060997	18	1	18204	49	CTNND2
4.752e-02	-3.05	A/G_cyclase	interpro domains	IPR001054	18	1	18521	50	ADCY2
4.752e-02	-3.05	Nucleotide_cyclase	interpro domains	IPR029787	18	1	18521	50	ADCY2
4.752e-02	-3.05	Leu-rich_rpt_Cys-con_subtyp	interpro domains	IPR006553	18	1	18521	50	FBXL7
4.764e-02	-3.04	GABA-A receptor complex	cellular component	GO:1902711	19	1	19108	49	GABRB1
4.764e-02	-3.04	postsynaptic specialization, intracellular component	cellular component	GO:0099091	19	1	19108	49	TNIK
4.764e-02	-3.04	astrocyte projection	cellular component	GO:0097449	19	1	19108	49	SLC1A2
4.764e-02	-3.04	cation-transporting ATPase complex	cellular component	GO:0090533	19	1	19108	49	ATP1A2
4.764e-02	-3.04	parallel fiber to Purkinje cell synapse	cellular component	GO:0098688	19	1	19108	49	GPM6A
4.772e-02	-3.04	haematopoietic_and_lymphoid_tissue-abdomen-lymphoid_neoplasm-diffuse_large_B_cell_lymphoma	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue-abdomen-lymphoid_neoplasm-diffuse_large_B_cell_lymphoma	120	2	16828	49	FMN2,CTNND2
4.774e-02	-3.04	C3orf62 (chromosome 3 open reading frame 62)	protein interactions	375341	19	1	19454	50	ATP1A2
4.774e-02	-3.04	PHYHIPL (phytanoyl-CoA 2-hydroxylase interacting protein like)	protein interactions	84457	19	1	19454	50	GPM6A
4.774e-02	-3.04	NLGN1 (neuroligin 1)	protein interactions	22871	19	1	19454	50	NRXN1
4.774e-02	-3.04	INKA1 (inka box actin regulator 1)	protein interactions	389119	19	1	19454	50	ZBTB20
4.774e-02	-3.04	EGFL6 (EGF like domain multiple 6)	protein interactions	25975	19	1	19454	50	LRP1B
4.774e-02	-3.04	RIT2 (Ras like without CAAX 2)	protein interactions	6014	19	1	19454	50	DTNA
4.774e-02	-3.04	SPZ1 (spermatogenic leucine zipper 1)	protein interactions	84654	19	1	19454	50	DTNA
4.774e-02	-3.04	SYT7 (synaptotagmin 7)	protein interactions	9066	19	1	19454	50	NRXN1
4.774e-02	-3.04	TNR (tenascin R)	protein interactions	7143	19	1	19454	50	PTPRZ1
4.781e-02	-3.04	Inflammatory mediator regulation of TRP channels	KEGG pathways	ko04750	97	2	7161	26	ITPR2,ADCY2
4.781e-02	-3.04	Inflammatory mediator regulation of TRP channels	KEGG pathways	hsa04750	97	2	7161	26	ADCY2,ITPR2
4.839e-02	-3.03	squamous_cell_carcinoma_BRAF_inhibitor_related	COSMIC cancer mutations	squamous_cell_carcinoma_BRAF_inhibitor_related	17	1	16828	49	FGFR3
4.839e-02	-3.03	non_chronically_sun_exposed_site	COSMIC cancer mutations	non_chronically_sun_exposed_site	17	1	16828	49	FGFR3
4.839e-02	-3.03	skin-other-verrucal_keratosis_BRAF_inhibitor_related	COSMIC cancer mutations	skin-other-verrucal_keratosis_BRAF_inhibitor_related	17	1	16828	49	FGFR3
4.839e-02	-3.03	breast-carcinoma-neuroendocrine_carcinoma	COSMIC cancer mutations	breast-carcinoma-neuroendocrine_carcinoma	17	1	16828	49	FGFR3
4.839e-02	-3.03	verrucal_keratosis_BRAF_inhibitor_related	COSMIC cancer mutations	verrucal_keratosis_BRAF_inhibitor_related	17	1	16828	49	FGFR3
4.839e-02	-3.03	skin-non_chronically_sun_exposed_site-malignant_melanoma	COSMIC cancer mutations	skin-non_chronically_sun_exposed_site-malignant_melanoma	17	1	16828	49	FGFR3
4.839e-02	-3.03	skin-carcinoma-squamous_cell_carcinoma_BRAF_inhibitor_related	COSMIC cancer mutations	skin-carcinoma-squamous_cell_carcinoma_BRAF_inhibitor_related	17	1	16828	49	FGFR3
4.842e-02	-3.03	TBL1X (transducin beta like 1 X-linked)	protein interactions	6907	137	2	19454	50	NFIA,SOX5
4.844e-02	-3.03	Guanylate_cyc	pfam domains	PF00211	18	1	17795	49	ADCY2
4.848e-02	-3.03	PKA-mediated phosphorylation of CREB	REACTOME pathways	R-HSA-111931	17	1	10285	30	ADCY2
4.848e-02	-3.03	Elevation of cytosolic Ca2+ levels	REACTOME pathways	R-HSA-139853	17	1	10285	30	ITPR2
4.848e-02	-3.03	PKA activation in glucagon signalling	REACTOME pathways	R-HSA-164378	17	1	10285	30	ADCY2
4.852e-02	-3.03	carboxylic acid transmembrane transport	biological process	GO:1905039	131	2	18204	49	SLC1A3,SLC1A2
4.859e-02	-3.02	human chr18q12.1	chromosome location	human chr18q12.1	26	1	26134	50	DTNA
4.870e-02	-3.02	Estrogen signaling pathway	KEGG pathways	ko04915	98	2	7161	26	ITPR2,ADCY2
4.870e-02	-3.02	Estrogen signaling pathway	KEGG pathways	hsa04915	98	2	7161	26	ITPR2,ADCY2
4.879e-02	-3.02	transport	biological process	GO:0006810	3615	15	18204	49	SLC1A2,GABRB1,FMN2,ATP13A4,PITPNC1,GPM6A,SLC1A3,LRP1B,CPE,NRXN1,ATP1A2,ITPR2,APOE,RANBP3L,NTRK2
4.905e-02	-3.01	NFIB (nuclear factor I B)	protein interactions	4781	138	2	19454	50	NFIA,SOX5
4.916e-02	-3.01	response to decreased oxygen levels	biological process	GO:0036293	306	3	18204	49	FMN2,RORA,ITPR2
4.918e-02	-3.01	inorganic anion transmembrane transport	biological process	GO:0098661	132	2	18204	49	SLC1A3,GABRB1
4.924e-02	-3.01	alkali metal ion binding	molecular function	GO:0031420	19	1	18094	48	ATP1A2
4.924e-02	-3.01	transmembrane receptor protein serine/threonine kinase activity	molecular function	GO:0004675	19	1	18094	48	BMPR1B
4.924e-02	-3.01	GABA-A receptor activity	molecular function	GO:0004890	19	1	18094	48	GABRB1
4.936e-02	-3.01	Alpha carbonic anhydrase	gene3d domains	3.10.200.10	17	1	14470	43	PTPRZ1
4.936e-02	-3.01	-	gene3d domains	2.60.120.1000	17	1	14470	43	COL5A3
4.937e-02	-3.01	monoatomic ion homeostasis	biological process	GO:0050801	515	4	18204	49	APOE,ATP13A4,SLC1A3,ATP1A2
4.968e-02	-3.00	SPCS2 (signal peptidase complex subunit 2)	protein interactions	9789	139	2	19454	50	GPC5,MGAT4C
4.968e-02	-3.00	NEFM (neurofilament medium chain)	protein interactions	4741	139	2	19454	50	TNIK,APOE
4.985e-02	-3.00	regulation of sequestering of calcium ion	biological process	GO:0051282	133	2	18204	49	ITPR2,ATP1A2
4.995e-02	-3.00	vocalization behavior	biological process	GO:0071625	19	1	18204	49	NRXN1
4.995e-02	-3.00	excitatory synapse assembly	biological process	GO:1904861	19	1	18204	49	NRXN1
4.995e-02	-3.00	microvillus organization	biological process	GO:0032528	19	1	18204	49	TNIK
4.995e-02	-3.00	chondroitin sulfate biosynthetic process	biological process	GO:0030206	19	1	18204	49	CSGALNACT1
4.995e-02	-3.00	regulation of amyloid-beta clearance	biological process	GO:1900221	19	1	18204	49	APOE
4.995e-02	-3.00	cerebellar Purkinje cell layer morphogenesis	biological process	GO:0021692	19	1	18204	49	RORA
4.995e-02	-3.00	response to potassium ion	biological process	GO:0035864	19	1	18204	49	ATP1A2
4.995e-02	-3.00	regulation of neurotransmitter uptake	biological process	GO:0051580	19	1	18204	49	ATP1A2
4.995e-02	-3.00	regulation of glutamate secretion	biological process	GO:0014048	19	1	18204	49	PRKG1