Gene Ontology Enrichment Results

Homer de novo Motif Enrichment Results
Known Motif Enrichment Results

Text file version of complete results (i.e. open with Excel)

biological process: Functional groupings of proteins (Gene Ontology)

molecular function: Mechanistic actions of proteins (Gene Ontology)

cellular component: Protein localization (Gene Ontology)

chromosome location: Genes with similar chromosome localization (NCBI Gene)

KEGG pathways: Groups of proteins in the same pathways (KEGG)

protein interactions: "Proteins interacting with a common protein (BIND, EcoCyc, HPRD)" (NCBI Gene)

interpro domains: Proteins with similar domains and features (Interpro)

pfam domains: Proteins with similar domains and features (Pfam)

smart domains: Proteins with similar domains and features (SMART)

gene3d domains: Proteins with similar domains and features (Gene3D)

prosite domains: Proteins with similar domains and features (Prosite)

prints domains: Proteins with similar domains and features (PRINTS)

MSigDB lists: "Genes sets for pathways, factor/miRNA target predictions, expression patterns, etc." (MSigDB)

BIOCYC pathways: Groups of proteins in the same pathways (BIOCYC)

COSMIC cancer mutations: Genes mutated in similar cancers (COSMIC)

GWAS genes: Genes mutated in similar diseases (GWAS Catalog)

Lipid Maps pathways: Groups of proteins in the same lipid pathways (Lipid Maps/Biosystems)

Pathway Interaction DB: Groups of proteins in the same pathways (Pathway Interaction Database)

REACTOME pathways: Groups of proteins in the same pathways (REACTOME)

SMPDB pathways: Groups of proteins in the same pathways (SMPDB)

WikiPathways: Groups of proteins in the same pathways (Wikipathways)

Enriched Categories

P-value	ln(P)	Term	GO Tree	GO ID	# of Genes in Term	# of Target Genes in Term	# of Total Genes	# of Target Genes	Common Genes
1.522e-09	-20.30	nervous system development	biological process	GO:0007399	2185	23	18204	49	PCDH9,NRXN1,NTM,CLU,TNIK,BMPR1B,SLC1A2,CTNND2,ATP1A2,PTPRZ1,NRG3,NFIB,GLUD1,PREX2,SLC1A3,GPM6A,MSI2,NTRK2,NFIA,QKI,SOX5,LSAMP,RORA
1.647e-09	-20.22	brainstem	COSMIC cancer mutations	brainstem	3102	28	16828	49	SLC1A3,SLC1A2,NFIB,CDH20,FBXL7,RORA,LSAMP,ADCY2,ATP13A4,SFXN5,CTNND2,PREX2,LIFR,PCDH9,FMN2,TNIK,ZBTB20,ITPR2,NPAS3,QKI,NRG3,PRKCA,GPM6A,FGFR3,NKAIN3,PTPRZ1,SOX5,CPE
2.096e-09	-19.98	diffuse_large_B_cell_lymphoma	COSMIC cancer mutations	diffuse_large_B_cell_lymphoma	4151	32	16828	49	CPE,SOX5,NKAIN3,FGFR3,ATP1A2,AQP4,GPM6A,PRKCA,NRG3,MACF1,QKI,DTNA,ITPR2,FMN2,PCDH9,LIFR,TNIK,CTNND2,PREX2,ATP13A4,CSGALNACT1,ADCY2,LSAMP,EFEMP1,RORA,CLU,FBXL7,CDH20,NFIB,SLC1A2,NTRK2,SLC1A3
3.796e-09	-19.39	central_nervous_system-brainstem-glioma-astrocytoma_Grade_IV	COSMIC cancer mutations	central_nervous_system-brainstem-glioma-astrocytoma_Grade_IV	2531	25	16828	49	PREX2,CTNND2,SFXN5,PCDH9,FMN2,TNIK,LIFR,ZBTB20,ATP13A4,FBXL7,CDH20,ADCY2,RORA,LSAMP,SLC1A3,NFIB,SOX5,PTPRZ1,CPE,NKAIN3,PRKCA,NRG3,GPM6A,ITPR2,QKI
5.541e-09	-19.01	system development	biological process	GO:0048731	3533	28	18204	49	PCDH9,NRXN1,CPE,BMPR1B,CSGALNACT1,FGFR3,SLC1A2,ATP1A2,CTNND2,NTM,CLU,TNIK,GLUD1,SLC1A3,GPM6A,PREX2,MSI2,PTPRZ1,EFEMP1,NRG3,NFIB,LSAMP,RORA,NTRK2,NFIA,PRKCA,QKI,SOX5
6.200e-09	-18.90	prostate-carcinoma	COSMIC cancer mutations	prostate-carcinoma	9000	45	16828	49	SOX5,PTPRZ1,CPE,NKAIN3,NHSL1,NRG3,PRKCA,PON2,GLIS3,MACF1,FGFR3,GPM6A,NPAS3,ITPR2,NFIA,QKI,DTNA,PREX2,CTNND2,SFXN5,MSI2,ZBTB20,PARD3B,FMN2,LIFR,TNIK,PCDH9,CSGALNACT1,GLUD1,ATP13A4,BMPR1B,PITPNC1,CLU,FBXL7,CDH20,NTM,ADCY2,LSAMP,EFEMP1,RORA,NRXN1,SLC1A3,NTRK2,NFIB,SLC1A2
8.189e-09	-18.62	acute_lymphoblastic_B_cell_leukaemia	COSMIC cancer mutations	acute_lymphoblastic_B_cell_leukaemia	3828	30	16828	49	ZBTB20,LIFR,FMN2,PCDH9,TNIK,CTNND2,PREX2,BMPR1B,ATP13A4,CSGALNACT1,ADCY2,LSAMP,RORA,FBXL7,NTM,NFIB,SLC1A2,MGAT4C,NRXN1,NTRK2,SLC1A3,CPE,SOX5,PTPRZ1,NKAIN3,GPM6A,NRG3,GLIS3,ITPR2,NFIA
8.189e-09	-18.62	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-acute_lymphoblastic_B_cell_leukaemia	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-acute_lymphoblastic_B_cell_leukaemia	3828	30	16828	49	NKAIN3,CPE,PTPRZ1,SOX5,ITPR2,NFIA,GPM6A,GLIS3,NRG3,ATP13A4,BMPR1B,CSGALNACT1,ZBTB20,TNIK,FMN2,LIFR,PCDH9,CTNND2,PREX2,SLC1A2,NFIB,NTRK2,NRXN1,SLC1A3,MGAT4C,LSAMP,RORA,ADCY2,NTM,FBXL7
1.050e-08	-18.37	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-diffuse_large_B_cell_lymphoma	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-diffuse_large_B_cell_lymphoma	3608	29	16828	49	ITPR2,QKI,MACF1,PRKCA,NRG3,ATP1A2,GPM6A,AQP4,FGFR3,NKAIN3,SOX5,CPE,SLC1A2,NFIB,CDH20,CLU,FBXL7,LSAMP,EFEMP1,RORA,ADCY2,CSGALNACT1,ATP13A4,CTNND2,PREX2,PCDH9,FMN2,LIFR,TNIK
1.362e-08	-18.11	anatomical structure morphogenesis	biological process	GO:0009653	2225	22	18204	49	BMPR1B,FGFR3,CTNND2,CSGALNACT1,CLU,TNIK,NRXN1,CPE,CDH20,RORA,NTRK2,QKI,SOX5,NFIA,PRKCA,SLC1A3,GPM6A,PREX2,NRG3,PTPRZ1,EFEMP1,NFIB
1.464e-08	-18.04	multicellular organism development	biological process	GO:0007275	3957	29	18204	49	NRG3,PTPRZ1,EFEMP1,NFIB,GLUD1,PREX2,SLC1A3,MSI2,GPM6A,NTRK2,QKI,SOX5,PRKCA,NFIA,RORA,LSAMP,CDH20,NRXN1,PCDH9,CPE,CLU,NTM,TNIK,BMPR1B,CTNND2,ATP1A2,SLC1A2,FGFR3,CSGALNACT1
1.500e-08	-18.01	myelodysplastic_syndrome	COSMIC cancer mutations	myelodysplastic_syndrome	1174	17	16828	49	TNIK,SOX5,PREX2,BMPR1B,NKAIN3,ATP1A2,LSAMP,FGFR3,ADCY2,FBXL7,PRKCA,NRG3,SLC1A2,NFIB,NFIA,NTRK2,NPAS3
1.500e-08	-18.01	haematopoietic_and_lymphoid_tissue-haematopoietic_neoplasm-myelodysplastic_syndrome	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue-haematopoietic_neoplasm-myelodysplastic_syndrome	1174	17	16828	49	FGFR3,ADCY2,ATP1A2,LSAMP,PRKCA,FBXL7,NRG3,NFIB,SLC1A2,NPAS3,NFIA,NTRK2,TNIK,SOX5,PREX2,BMPR1B,NKAIN3
2.351e-08	-17.57	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-Burkitt_lymphoma	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-Burkitt_lymphoma	2119	22	16828	49	FBXL7,NRG3,LSAMP,GPM6A,ADCY2,SLC1A3,NTRK2,ITPR2,NPAS3,SLC1A2,NFIB,PREX2,CTNND2,SOX5,FMN2,PCDH9,CPE,NKAIN3,CSGALNACT1,NHSL1,BMPR1B,ATP13A4
2.351e-08	-17.57	Burkitt_lymphoma	COSMIC cancer mutations	Burkitt_lymphoma	2119	22	16828	49	PREX2,CTNND2,SOX5,PCDH9,FMN2,CPE,NKAIN3,CSGALNACT1,NHSL1,ATP13A4,BMPR1B,NRG3,FBXL7,LSAMP,GPM6A,ADCY2,SLC1A3,NTRK2,ITPR2,NPAS3,SLC1A2,NFIB
1.551e-07	-15.68	central_nervous_system-brain-primitive_neuroectodermal_tumour-medulloblastoma	COSMIC cancer mutations	central_nervous_system-brain-primitive_neuroectodermal_tumour-medulloblastoma	7205	39	16828	49	GPM6A,FGFR3,PON2,MACF1,GLIS3,PRKCA,NRG3,QKI,NFIA,ITPR2,NPAS3,CPE,PTPRZ1,SOX5,NHSL1,NKAIN3,LSAMP,RORA,ADCY2,NTM,FBXL7,SLC1A2,NFIB,NTRK2,NRXN1,SLC1A3,PARD3B,ZBTB20,TNIK,PCDH9,LIFR,FMN2,SFXN5,PREX2,CTNND2,PITPNC1,ATP13A4,GLUD1,CSGALNACT1
1.940e-07	-15.46	cell morphogenesis	biological process	GO:0000902	687	12	18204	49	NFIA,TNIK,CLU,CTNND2,BMPR1B,CDH20,NFIB,PTPRZ1,PREX2,SLC1A3,GPM6A,NRXN1
2.088e-07	-15.38	neurogenesis	biological process	GO:0022008	1334	16	18204	49	CLU,NTRK2,NTM,SOX5,QKI,NFIA,TNIK,BMPR1B,CTNND2,RORA,PTPRZ1,NFIB,NRXN1,SLC1A3,PREX2,GPM6A
3.797e-07	-14.78	pharynx	COSMIC cancer mutations	pharynx	2696	23	16828	49	CTNND2,PREX2,PTPRZ1,SFXN5,FMN2,PCDH9,PARD3B,ATP13A4,NHSL1,PITPNC1,PRKCA,NRG3,CLU,MACF1,FGFR3,EFEMP1,ATP1A2,NPAS3,NFIA,NTRK2,QKI,SLC1A2,DTNA
5.280e-07	-14.45	PRNP (prion protein (Kanno blood group))	protein interactions	5621	1118	14	19454	50	AQP4,MACF1,QKI,PTPRZ1,MSI2,NFIB,NHSL1,CPE,CLU,LSAMP,GPM6A,GLUD1,ATP1A2,SLC1A3
1.041e-06	-13.78	mantle_cell_lymphoma	COSMIC cancer mutations	mantle_cell_lymphoma	2849	23	16828	49	SLC1A3,NTRK2,NFIB,SLC1A2,FBXL7,ADCY2,LSAMP,EFEMP1,ATP13A4,CTNND2,PREX2,SFXN5,PARD3B,PCDH9,FMN2,LIFR,ITPR2,NRG3,PRKCA,GPM6A,NKAIN3,SOX5,CPE
1.167e-06	-13.66	cell periphery	cellular component	GO:0071944	6020	32	19108	49	AQP4,CLU,PTPRZ1,MACF1,SLC1A2,EFEMP1,PON2,ATP1A2,ATP13A4,PRKCA,FMN2,NTM,NTRK2,PARD3B,CDH20,TNIK,NRG3,PCDH9,CTNND2,NRXN1,ITPR2,GPM6A,LIFR,ADCY2,CPE,BMPR1B,NKAIN3,SLC1A3,FGFR3,PREX2,DTNA,LSAMP
1.354e-06	-13.51	generation of neurons	biological process	GO:0048699	1158	14	18204	49	BMPR1B,CTNND2,RORA,NTRK2,NTM,SOX5,NFIA,TNIK,NRXN1,GPM6A,SLC1A3,PREX2,PTPRZ1,NFIB
1.377e-06	-13.50	haematopoietic_and_lymphoid_tissue-haematopoietic_neoplasm	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue-haematopoietic_neoplasm	764	12	16828	49	NKAIN3,NTRK2,SLC1A2,NFIB,SOX5,FBXL7,NRG3,PREX2,PCDH9,ATP1A2,LSAMP,ADCY2
1.499e-06	-13.41	central nervous system development	biological process	GO:0007417	995	13	18204	49	PTPRZ1,NRG3,NFIB,PCDH9,GLUD1,MSI2,NTRK2,CLU,QKI,BMPR1B,RORA,SLC1A2,ATP1A2
1.959e-06	-13.14	anatomical structure development	biological process	GO:0048856	5207	30	18204	49	CPE,PCDH9,NRXN1,CDH20,CSGALNACT1,ATP1A2,CTNND2,SLC1A2,FGFR3,BMPR1B,TNIK,NTM,CLU,PREX2,SLC1A3,MSI2,GPM6A,GLUD1,NFIB,EFEMP1,PTPRZ1,NRG3,RORA,LSAMP,PRKCA,NFIA,QKI,SOX5,FMN2,NTRK2
2.259e-06	-13.00	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-mantle_cell_lymphoma	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-mantle_cell_lymphoma	2737	22	16828	49	GPM6A,NRG3,PRKCA,ITPR2,CPE,SOX5,NKAIN3,ADCY2,EFEMP1,LSAMP,FBXL7,NFIB,SLC1A2,SLC1A3,NTRK2,FMN2,PCDH9,LIFR,PARD3B,CTNND2,PREX2,SFXN5
2.567e-06	-12.87	chondroblastoma	COSMIC cancer mutations	chondroblastoma	534	10	16828	49	NKAIN3,GPM6A,PCDH9,FMN2,LSAMP,ADCY2,SFXN5,NRG3,SOX5,CTNND2
2.650e-06	-12.84	plasma membrane	cellular component	GO:0005886	5538	30	19108	49	PTPRZ1,MACF1,SLC1A2,PON2,ATP1A2,AQP4,NTRK2,PARD3B,CDH20,ATP13A4,PRKCA,FMN2,NTM,PCDH9,NRXN1,CTNND2,ITPR2,GPM6A,LIFR,TNIK,NRG3,PREX2,FGFR3,DTNA,LSAMP,CPE,ADCY2,BMPR1B,NKAIN3,SLC1A3
2.806e-06	-12.78	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-chronic_lymphocytic_leukaemia-small_lymphocytic_lymphoma	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-chronic_lymphocytic_leukaemia-small_lymphocytic_lymphoma	3511	25	16828	49	MGAT4C,SLC1A3,NTRK2,CLU,FBXL7,ADCY2,LSAMP,EFEMP1,BMPR1B,PITPNC1,PREX2,CTNND2,PARD3B,MSI2,TNIK,LIFR,PCDH9,FMN2,NPAS3,DTNA,PRKCA,NRG3,MACF1,PTPRZ1,CPE
2.806e-06	-12.78	chronic_lymphocytic_leukaemia-small_lymphocytic_lymphoma	COSMIC cancer mutations	chronic_lymphocytic_leukaemia-small_lymphocytic_lymphoma	3511	25	16828	49	NPAS3,DTNA,MACF1,PRKCA,NRG3,PTPRZ1,CPE,NTRK2,SLC1A3,MGAT4C,FBXL7,CLU,EFEMP1,LSAMP,ADCY2,PITPNC1,BMPR1B,PREX2,CTNND2,LIFR,TNIK,PCDH9,FMN2,MSI2,PARD3B
3.102e-06	-12.68	lymphoid_neoplasm	COSMIC cancer mutations	lymphoid_neoplasm	12233	48	16828	49	CSGALNACT1,SFXN5,PREX2,CTNND2,PCDH9,FMN2,ZBTB20,NTM,FBXL7,CLU,ADCY2,NKAIN3,NHSL1,PTPRZ1,CPE,DTNA,PON2,NRG3,GPM6A,AQP4,ATP1A2,FGFR3,GLUD1,PITPNC1,ATP13A4,BMPR1B,TNIK,LIFR,MSI2,PARD3B,NTRK2,NRXN1,SLC1A3,MGAT4C,SLC1A2,NFIB,CDH20,EFEMP1,RORA,LSAMP,SOX5,ITPR2,NFIA,NPAS3,QKI,GLIS3,MACF1,PRKCA
3.116e-06	-12.68	lymph_node	COSMIC cancer mutations	lymph_node	1703	17	16828	49	PRKCA,NRG3,LSAMP,GPM6A,FGFR3,SLC1A3,NTRK2,ITPR2,DTNA,SFXN5,CTNND2,SOX5,PARD3B,LIFR,PCDH9,TNIK,ATP13A4
3.759e-06	-12.49	neuron differentiation	biological process	GO:0030182	1081	13	18204	49	NTM,NTRK2,NFIA,TNIK,BMPR1B,RORA,CTNND2,PTPRZ1,NFIB,NRXN1,GPM6A,SLC1A3,PREX2
4.299e-06	-12.36	developmental process	biological process	GO:0032502	5716	31	18204	49	FMN2,NTRK2,SOX5,QKI,PRKCA,NFIA,RORA,LSAMP,NRG3,PTPRZ1,EFEMP1,NFIB,GLUD1,SLC1A3,MSI2,PREX2,GPM6A,CLU,NTM,NHSL1,TNIK,BMPR1B,CTNND2,ATP1A2,SLC1A2,FGFR3,CSGALNACT1,CDH20,NRXN1,PCDH9,CPE
4.679e-06	-12.27	cell junction	cellular component	GO:0030054	2224	18	19108	49	SLC1A3,NFIA,FGFR3,NTRK2,PARD3B,CDH20,DTNA,TNIK,NRG3,GPM6A,ATP1A2,CLU,QKI,PCDH9,PTPRZ1,NRXN1,CTNND2,SLC1A2
4.959e-06	-12.21	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm	7307	37	16828	49	GPM6A,NRG3,PRKCA,GLIS3,MACF1,PON2,QKI,ITPR2,CPE,SOX5,PTPRZ1,NHSL1,NKAIN3,ADCY2,EFEMP1,RORA,LSAMP,FBXL7,CLU,CDH20,NFIB,SLC1A2,MGAT4C,NTRK2,SLC1A3,TNIK,PCDH9,FMN2,LIFR,PARD3B,PREX2,CTNND2,SFXN5,ATP13A4,BMPR1B,GLUD1,CSGALNACT1
6.731e-06	-11.91	cartilage development	biological process	GO:0051216	173	6	18204	49	FGFR3,CSGALNACT1,BMPR1B,NFIB,SOX5,NFIA
7.624e-06	-11.78	upper_aerodigestive_tract-pharynx-carcinoma-nasopharyngeal_carcinoma	COSMIC cancer mutations	upper_aerodigestive_tract-pharynx-carcinoma-nasopharyngeal_carcinoma	1425	15	16828	49	NFIA,NTRK2,SLC1A2,QKI,PRKCA,CLU,ATP1A2,FGFR3,NHSL1,PITPNC1,ATP13A4,SFXN5,PREX2,CTNND2,FMN2
7.624e-06	-11.78	nasopharyngeal_carcinoma	COSMIC cancer mutations	nasopharyngeal_carcinoma	1425	15	16828	49	QKI,SLC1A2,NFIA,NTRK2,FGFR3,ATP1A2,PRKCA,CLU,ATP13A4,NHSL1,PITPNC1,FMN2,PREX2,CTNND2,SFXN5
1.002e-05	-11.51	cerebellum	COSMIC cancer mutations	cerebellum	769	11	16828	49	QKI,ITPR2,NTRK2,NRXN1,NPAS3,PCDH9,PARD3B,CPE,PTPRZ1,NRG3,CTNND2
1.359e-05	-11.21	neuron development	biological process	GO:0048666	859	11	18204	49	NTM,NTRK2,TNIK,BMPR1B,CTNND2,PTPRZ1,NFIB,NRXN1,SLC1A3,GPM6A,PREX2
1.509e-05	-11.10	central_nervous_system-cerebellum-primitive_neuroectodermal_tumour-medulloblastoma-SHH_subtype	COSMIC cancer mutations	central_nervous_system-cerebellum-primitive_neuroectodermal_tumour-medulloblastoma-SHH_subtype	653	10	16828	49	NTRK2,NRXN1,ITPR2,NPAS3,PARD3B,PCDH9,CPE,PTPRZ1,CTNND2,NRG3
1.529e-05	-11.09	SHH_subtype	COSMIC cancer mutations	SHH_subtype	654	10	16828	49	NPAS3,NTRK2,NRXN1,ITPR2,CTNND2,NRG3,PTPRZ1,CPE,PARD3B,PCDH9
1.702e-05	-10.98	acute_myeloid_leukaemia_therapy_related	COSMIC cancer mutations	acute_myeloid_leukaemia_therapy_related	1523	15	16828	49	ITPR2,NTRK2,SLC1A3,QKI,FBXL7,NRG3,ADCY2,RORA,LSAMP,NKAIN3,SOX5,CTNND2,PREX2,PCDH9,FMN2
1.702e-05	-10.98	haematopoietic_and_lymphoid_tissue-haematopoietic_neoplasm-acute_myeloid_leukaemia_therapy_related	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue-haematopoietic_neoplasm-acute_myeloid_leukaemia_therapy_related	1523	15	16828	49	CTNND2,PREX2,SOX5,PCDH9,FMN2,NKAIN3,NRG3,FBXL7,LSAMP,RORA,ADCY2,NTRK2,SLC1A3,ITPR2,QKI
1.881e-05	-10.88	upper_aerodigestive_tract-larynx-carcinoma-squamous_cell_carcinoma	COSMIC cancer mutations	upper_aerodigestive_tract-larynx-carcinoma-squamous_cell_carcinoma	1946	17	16828	49	ITPR2,NRXN1,MGAT4C,NPAS3,RBMS3,MACF1,RORA,GPM6A,FGFR3,CSGALNACT1,BMPR1B,SOX5,TNIK,PCDH9,FMN2,PARD3B,ZBTB20
1.907e-05	-10.87	larynx	COSMIC cancer mutations	larynx	1948	17	16828	49	SOX5,ZBTB20,PARD3B,PCDH9,FMN2,TNIK,CSGALNACT1,BMPR1B,MACF1,GPM6A,RORA,FGFR3,NRXN1,ITPR2,MGAT4C,NPAS3,RBMS3
2.188e-05	-10.73	tibia	COSMIC cancer mutations	tibia	836	11	16828	49	CTNND2,PREX2,TNIK,CPE,NKAIN3,MACF1,GPM6A,LSAMP,FGFR3,QKI,NFIB
2.531e-05	-10.58	multicellular organismal process	biological process	GO:0032501	6177	31	18204	49	CLU,NTM,TNIK,BMPR1B,SLC1A2,ATP1A2,CTNND2,FGFR3,CSGALNACT1,AQP4,CDH20,NRXN1,PCDH9,CPE,NTRK2,QKI,SOX5,PRKCA,NFIA,RORA,LSAMP,NRG3,EFEMP1,PTPRZ1,NFIB,GLUD1,DTNA,SLC1A3,PREX2,MSI2,GPM6A
2.544e-05	-10.58	blood_vessel	COSMIC cancer mutations	blood_vessel	2211	18	16828	49	NKAIN3,PCDH9,FMN2,SOX5,CTNND2,PREX2,PTPRZ1,SLC1A2,ITPR2,NTRK2,SLC1A3,FGFR3,ADCY2,GPM6A,LSAMP,NRG3,FBXL7,CDH20
2.571e-05	-10.57	glial cell differentiation	biological process	GO:0010001	219	6	18204	49	CLU,NTRK2,PTPRZ1,QKI,NFIB,NFIA
2.915e-05	-10.44	follicular_lymphoma	COSMIC cancer mutations	follicular_lymphoma	1209	13	16828	49	NKAIN3,SOX5,CTNND2,PCDH9,TNIK,ITPR2,PRKCA,NRG3,AQP4,EFEMP1,RORA,LSAMP,ADCY2
3.125e-05	-10.37	Glutamatergic synapse	KEGG pathways	ko04724	114	5	7161	24	ITPR2,ADCY2,SLC1A3,SLC1A2,PRKCA
3.125e-05	-10.37	Glutamatergic synapse	KEGG pathways	hsa04724	114	5	7161	24	PRKCA,SLC1A3,SLC1A2,ADCY2,ITPR2
3.552e-05	-10.25	connective tissue development	biological process	GO:0061448	232	6	18204	49	BMPR1B,FGFR3,SOX5,NFIB,NFIA,CSGALNACT1
4.197e-05	-10.08	neuron projection morphogenesis	biological process	GO:0048812	486	8	18204	49	TNIK,NFIB,PTPRZ1,PREX2,GPM6A,CTNND2,BMPR1B,NRXN1
4.271e-05	-10.06	CTF/NFI_DNA-bd_CS	interpro domains	IPR019739	4	2	18521	50	NFIA,NFIB
4.271e-05	-10.06	CTF/NFI_DNA-bd-dom	interpro domains	IPR020604	4	2	18521	50	NFIB,NFIA
4.271e-05	-10.06	CTF/NFI	interpro domains	IPR000647	4	2	18521	50	NFIB,NFIA
4.271e-05	-10.06	CTF/NFI_DNA-bd_N	interpro domains	IPR019548	4	2	18521	50	NFIA,NFIB
4.441e-05	-10.02	CTF_NFI	pfam domains	PF00859	4	2	17795	49	NFIB,NFIA
4.441e-05	-10.02	NfI_DNAbd_pre-N	pfam domains	PF10524	4	2	17795	49	NFIB,NFIA
4.512e-05	-10.01	plasma membrane bounded cell projection morphogenesis	biological process	GO:0120039	491	8	18204	49	NRXN1,BMPR1B,PREX2,GPM6A,CTNND2,PTPRZ1,NFIB,TNIK
4.847e-05	-9.93	cell projection morphogenesis	biological process	GO:0048858	496	8	18204	49	BMPR1B,NRXN1,GPM6A,CTNND2,PREX2,PTPRZ1,TNIK,NFIB
5.256e-05	-9.85	Astrocytic Glutamate-Glutamine Uptake And Metabolism	REACTOME pathways	R-HSA-210455	4	2	10285	31	SLC1A3,SLC1A2
5.256e-05	-9.85	Neurotransmitter uptake and Metabolism In Glial Cells	REACTOME pathways	R-HSA-112313	4	2	10285	31	SLC1A3,SLC1A2
5.477e-05	-9.81	cell projection	cellular component	GO:0042995	2398	17	19108	49	CLU,PCDH9,NRXN1,CTNND2,MACF1,SLC1A2,GPM6A,NFIB,ATP1A2,AQP4,NTRK2,DTNA,ADCY2,BMPR1B,PRKCA,FMN2,SLC1A3
5.726e-05	-9.77	glial cell proliferation	biological process	GO:0014009	28	3	18204	49	CLU,NFIA,NFIB
6.097e-05	-9.71	retina development in camera-type eye	biological process	GO:0060041	156	5	18204	49	NTRK2,BMPR1B,NFIA,NFIB,GPM6A
6.103e-05	-9.70	synapse	cellular component	GO:0045202	1473	13	19108	49	TNIK,NRG3,GPM6A,ATP1A2,CLU,QKI,PTPRZ1,CTNND2,NRXN1,SLC1A2,SLC1A3,NTRK2,DTNA
6.242e-05	-9.68	transmembrane receptor protein kinase activity	molecular function	GO:0019199	81	4	18094	48	BMPR1B,FGFR3,EFEMP1,NTRK2
6.287e-05	-9.67	haematopoietic_and_lymphoid_tissue-lymph_node-lymphoid_neoplasm-mantle_cell_lymphoma	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue-lymph_node-lymphoid_neoplasm-mantle_cell_lymphoma	476	8	16828	49	ATP13A4,LSAMP,PCDH9,GPM6A,CTNND2,PRKCA,NRG3,SFXN5
6.856e-05	-9.59	high-affinity L-glutamate transmembrane transporter activity	molecular function	GO:0005314	5	2	18094	48	SLC1A2,SLC1A3
6.856e-05	-9.59	glutamate:sodium symporter activity	molecular function	GO:0015501	5	2	18094	48	SLC1A2,SLC1A3
6.928e-05	-9.58	CTF_NFI_2	prosite domains	PS51080	4	2	12186	42	NFIB,NFIA
6.928e-05	-9.58	CTF_NFI_1	prosite domains	PS00349	4	2	12186	42	NFIB,NFIA
7.061e-05	-9.56	D-aspartate import across plasma membrane	biological process	GO:0070779	5	2	18204	49	SLC1A3,SLC1A2
7.061e-05	-9.56	D-aspartate transmembrane transport	biological process	GO:0070777	5	2	18204	49	SLC1A2,SLC1A3
7.070e-05	-9.56	neurotransmitter uptake	biological process	GO:0001504	30	3	18204	49	SLC1A2,SLC1A3,ATP1A2
7.933e-05	-9.44	haematopoietic_and_lymphoid_tissue-haematopoietic_neoplasm-mast_cell_neoplasm	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue-haematopoietic_neoplasm-mast_cell_neoplasm	248	6	16828	49	PCDH9,ADCY2,NFIB,NFIA,NRG3,NPAS3
7.933e-05	-9.44	mast_cell_neoplasm	COSMIC cancer mutations	mast_cell_neoplasm	248	6	16828	49	NFIA,NRG3,NPAS3,PCDH9,ADCY2,NFIB
7.991e-05	-9.43	chondrocyte differentiation	biological process	GO:0002062	85	4	18204	49	FGFR3,NFIB,SOX5,BMPR1B
8.255e-05	-9.40	NTM (neurotrimin)	protein interactions	50863	33	3	19454	50	GPM6A,NTM,LSAMP
8.772e-05	-9.34	angiosarcoma	COSMIC cancer mutations	angiosarcoma	2192	17	16828	49	PCDH9,FMN2,CTNND2,PREX2,SOX5,PTPRZ1,NKAIN3,ADCY2,LSAMP,GPM6A,FBXL7,NRG3,CDH20,SLC1A2,SLC1A3,NTRK2,ITPR2
8.772e-05	-9.34	soft_tissue-blood_vessel-angiosarcoma	COSMIC cancer mutations	soft_tissue-blood_vessel-angiosarcoma	2192	17	16828	49	SLC1A3,NTRK2,ITPR2,SLC1A2,CDH20,NRG3,FBXL7,LSAMP,GPM6A,ADCY2,NKAIN3,PTPRZ1,CTNND2,PREX2,SOX5,FMN2,PCDH9
8.991e-05	-9.32	carcinoid-endocrine_tumour	COSMIC cancer mutations	carcinoid-endocrine_tumour	7752	36	16828	49	SOX5,PTPRZ1,CPE,NKAIN3,NHSL1,PRKCA,NRG3,GLIS3,MACF1,PON2,FGFR3,GPM6A,ATP1A2,ITPR2,QKI,PREX2,CTNND2,SFXN5,FMN2,LIFR,TNIK,PCDH9,CSGALNACT1,ATP13A4,BMPR1B,FBXL7,CLU,CDH20,ADCY2,EFEMP1,RORA,LSAMP,SLC1A3,NTRK2,NFIB,SLC1A2
9.123e-05	-9.30	gliogenesis	biological process	GO:0042063	275	6	18204	49	CLU,PTPRZ1,NTRK2,NFIB,QKI,NFIA
9.404e-05	-9.27	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-follicular_lymphoma	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-follicular_lymphoma	981	11	16828	49	ITPR2,NKAIN3,ADCY2,EFEMP1,RORA,PCDH9,LSAMP,NRG3,PRKCA,SOX5,CTNND2
9.447e-05	-9.27	response to auditory stimulus	biological process	GO:0010996	33	3	18204	49	ATP1A2,SLC1A3,NRXN1
9.548e-05	-9.26	Thyroid hormone synthesis	KEGG pathways	hsa04918	74	4	7161	24	ADCY2,ITPR2,ATP1A2,PRKCA
9.548e-05	-9.26	Thyroid hormone synthesis	KEGG pathways	ko04918	74	4	7161	24	ATP1A2,ADCY2,ITPR2,PRKCA
1.006e-04	-9.20	Gastric acid secretion	KEGG pathways	ko04971	75	4	7161	24	ATP1A2,ADCY2,ITPR2,PRKCA
1.006e-04	-9.20	Gastric acid secretion	KEGG pathways	hsa04971	75	4	7161	24	ATP1A2,ADCY2,ITPR2,PRKCA
1.023e-04	-9.19	neuron projection	cellular component	GO:0043005	1331	12	19108	49	SLC1A2,CTNND2,PCDH9,CLU,ATP1A2,NFIB,GPM6A,DTNA,NTRK2,BMPR1B,ADCY2,SLC1A3
1.057e-04	-9.15	D-amino acid transport	biological process	GO:0042940	6	2	18204	49	SLC1A2,SLC1A3
1.057e-04	-9.15	L-aspartate import across plasma membrane	biological process	GO:0140009	6	2	18204	49	SLC1A2,SLC1A3
1.149e-04	-9.07	plasma membrane bounded cell projection	cellular component	GO:0120025	2285	16	19108	49	AQP4,ATP1A2,GPM6A,NFIB,SLC1A2,CTNND2,MACF1,PCDH9,CLU,SLC1A3,FMN2,PRKCA,BMPR1B,ADCY2,DTNA,NTRK2
1.249e-04	-8.99	MAPT (microtubule associated protein tau)	protein interactions	4137	948	10	19454	50	CLU,PRKCA,TNIK,CTNND2,SLC1A2,GPM6A,ATP1A2,SLC1A3,NTM,LSAMP
1.317e-04	-8.94	skin-face-carcinoma-squamous_cell_carcinoma	COSMIC cancer mutations	skin-face-carcinoma-squamous_cell_carcinoma	2036	16	16828	49	CSGALNACT1,PTPRZ1,PREX2,MSI2,FMN2,PCDH9,ITPR2,RBMS3,NFIB,MACF1,NRG3,LSAMP,GPM6A,RORA,AQP4,FGFR3
1.393e-04	-8.88	DAG and IP3 signaling	REACTOME pathways	R-HSA-1489509	34	3	10285	31	ITPR2,ADCY2,PRKCA
1.478e-04	-8.82	glial cell fate specification	biological process	GO:0021780	7	2	18204	49	NFIB,NFIA
1.487e-04	-8.81	Na:dicarbo_symporter_sf	interpro domains	IPR036458	7	2	18521	50	SLC1A2,SLC1A3
1.487e-04	-8.81	Na-dicarboxylate_symporter_CS	interpro domains	IPR018107	7	2	18521	50	SLC1A3,SLC1A2
1.487e-04	-8.81	Na-dicarboxylate_symporter	interpro domains	IPR001991	7	2	18521	50	SLC1A3,SLC1A2
1.546e-04	-8.77	SDF	pfam domains	PF00375	7	2	17795	49	SLC1A3,SLC1A2
1.578e-04	-8.75	cell development	biological process	GO:0048468	2236	16	18204	49	NRXN1,PREX2,MSI2,GPM6A,SLC1A3,PTPRZ1,NFIB,BMPR1B,CTNND2,RORA,CLU,NTRK2,NTM,FMN2,QKI,TNIK
1.625e-04	-8.72	intestinal_adenocarcinoma	COSMIC cancer mutations	intestinal_adenocarcinoma	7225	34	16828	49	SFXN5,PREX2,CTNND2,PARD3B,ZBTB20,FMN2,LIFR,PCDH9,CSGALNACT1,PITPNC1,ATP13A4,NTM,CDH20,CLU,FBXL7,LSAMP,RORA,ADCY2,NTRK2,NRXN1,SLC1A2,PTPRZ1,SOX5,NHSL1,MACF1,NRG3,PRKCA,ATP1A2,AQP4,FGFR3,ITPR2,NFIA,NPAS3,QKI
1.625e-04	-8.72	stomach-carcinoma-intestinal_adenocarcinoma	COSMIC cancer mutations	stomach-carcinoma-intestinal_adenocarcinoma	7225	34	16828	49	NTRK2,NRXN1,SLC1A2,CLU,FBXL7,CDH20,NTM,ADCY2,LSAMP,RORA,CSGALNACT1,ATP13A4,PITPNC1,CTNND2,PREX2,SFXN5,PARD3B,ZBTB20,PCDH9,FMN2,LIFR,NPAS3,NFIA,ITPR2,QKI,PRKCA,NRG3,MACF1,FGFR3,ATP1A2,AQP4,NHSL1,SOX5,PTPRZ1
1.630e-04	-8.72	Sodium:dicarboxylate symporter	gene3d domains	1.10.3860.10	7	2	14470	41	SLC1A2,SLC1A3
1.655e-04	-8.71	PLC-gamma1 signalling	REACTOME pathways	R-HSA-167021	36	3	10285	31	ADCY2,ITPR2,PRKCA
1.655e-04	-8.71	EGFR interacts with phospholipase C-gamma	REACTOME pathways	R-HSA-212718	36	3	10285	31	PRKCA,ITPR2,ADCY2
1.712e-04	-8.67	cell morphogenesis involved in neuron differentiation	biological process	GO:0048667	443	7	18204	49	NRXN1,BMPR1B,CTNND2,SLC1A3,PREX2,PTPRZ1,NFIB
1.762e-04	-8.64	pancreas-carcinoid-endocrine_tumour	COSMIC cancer mutations	pancreas-carcinoid-endocrine_tumour	7250	34	16828	49	ATP13A4,BMPR1B,CSGALNACT1,LIFR,FMN2,PCDH9,SFXN5,PREX2,CTNND2,SLC1A2,NFIB,SLC1A3,NTRK2,LSAMP,RORA,EFEMP1,ADCY2,CDH20,CLU,FBXL7,NHSL1,NKAIN3,CPE,SOX5,QKI,ITPR2,ATP1A2,GPM6A,FGFR3,PON2,MACF1,GLIS3,NRG3,PRKCA
1.814e-04	-8.62	neural precursor cell proliferation	biological process	GO:0061351	105	4	18204	49	RORA,NFIA,SOX5,NFIB
1.874e-04	-8.58	bone-tibia-other-chondroblastoma	COSMIC cancer mutations	bone-tibia-other-chondroblastoma	98	4	16828	49	GPM6A,LSAMP,CTNND2,NKAIN3
2.046e-04	-8.49	Salivary secretion	KEGG pathways	ko04970	90	4	7161	24	ATP1A2,ADCY2,ITPR2,PRKCA
2.046e-04	-8.49	Salivary secretion	KEGG pathways	hsa04970	90	4	7161	24	ATP1A2,ADCY2,ITPR2,PRKCA
2.071e-04	-8.48	right_upper_lobe	COSMIC cancer mutations	right_upper_lobe	10376	42	16828	49	FBXL7,CDH20,NTM,ADCY2,LSAMP,EFEMP1,RORA,MGAT4C,SLC1A3,NTRK2,NRXN1,NFIB,SLC1A2,PREX2,CTNND2,SFXN5,PARD3B,ZBTB20,PCDH9,TNIK,FMN2,LIFR,CSGALNACT1,BMPR1B,ATP13A4,PITPNC1,PRKCA,NRG3,PON2,MACF1,GLIS3,FGFR3,ATP1A2,GPM6A,NPAS3,ITPR2,NFIA,DTNA,SOX5,PTPRZ1,CPE,NKAIN3
2.071e-04	-8.48	lung-right_upper_lobe-carcinoma-adenocarcinoma	COSMIC cancer mutations	lung-right_upper_lobe-carcinoma-adenocarcinoma	10376	42	16828	49	PREX2,CTNND2,SFXN5,PCDH9,TNIK,LIFR,FMN2,PARD3B,ZBTB20,CSGALNACT1,BMPR1B,ATP13A4,PITPNC1,FBXL7,CDH20,NTM,ADCY2,RORA,EFEMP1,LSAMP,MGAT4C,NTRK2,NRXN1,SLC1A3,NFIB,SLC1A2,SOX5,PTPRZ1,CPE,NKAIN3,NRG3,PRKCA,MACF1,GLIS3,PON2,FGFR3,GPM6A,ATP1A2,NPAS3,NFIA,ITPR2,DTNA
2.282e-04	-8.39	bone-humerus-other-chondroblastoma	COSMIC cancer mutations	bone-humerus-other-chondroblastoma	301	6	16828	49	NKAIN3,SFXN5,SOX5,FMN2,GPM6A,ADCY2
2.304e-04	-8.38	NEGR1 (neuronal growth regulator 1)	protein interactions	257194	9	2	19454	50	LSAMP,NTM
2.304e-04	-8.38	LSAMP (limbic system associated membrane protein)	protein interactions	4045	9	2	19454	50	LSAMP,NTM
2.355e-04	-8.35	face	COSMIC cancer mutations	face	2139	16	16828	49	PREX2,PTPRZ1,MSI2,FMN2,PCDH9,CSGALNACT1,NRG3,MACF1,FGFR3,LSAMP,AQP4,GPM6A,RORA,ITPR2,NFIB,RBMS3
2.402e-04	-8.33	acidic amino acid transport	biological process	GO:0015800	45	3	18204	49	SLC1A3,SLC1A2,NTRK2
2.409e-04	-8.33	NA_DICARBOXYL_SYMP_1	prosite domains	PS00713	7	2	12186	42	SLC1A2,SLC1A3
2.409e-04	-8.33	NA_DICARBOXYL_SYMP_2	prosite domains	PS00714	7	2	12186	42	SLC1A2,SLC1A3
2.520e-04	-8.29	Pancreatic secretion	KEGG pathways	ko04972	95	4	7161	24	ATP1A2,ADCY2,ITPR2,PRKCA
2.520e-04	-8.29	Pancreatic secretion	KEGG pathways	hsa04972	95	4	7161	24	PRKCA,ADCY2,ITPR2,ATP1A2
2.521e-04	-8.29	somatodendritic compartment	cellular component	GO:0036477	842	9	19108	49	ADCY2,BMPR1B,SLC1A3,NTRK2,CLU,NRXN1,CTNND2,GPM6A,ATP1A2
2.564e-04	-8.27	OCLN (occludin)	protein interactions	100506658	495	7	19454	50	EFEMP1,FMN2,DTNA,TNIK,PRKCA,NTRK2,MACF1
2.666e-04	-8.23	camera-type eye development	biological process	GO:0043010	335	6	18204	49	BMPR1B,GPM6A,EFEMP1,NTRK2,NFIB,NFIA
2.909e-04	-8.14	nodular	COSMIC cancer mutations	nodular	1515	13	16828	49	FMN2,CPE,PTPRZ1,PREX2,CTNND2,ATP13A4,ATP1A2,FGFR3,CDH20,GLIS3,MACF1,NTRK2,NPAS3
2.955e-04	-8.13	prostate-carcinoma-adenocarcinoma	COSMIC cancer mutations	prostate-carcinoma-adenocarcinoma	12379	46	16828	49	GLIS3,MACF1,PRKCA,QKI,NFIA,ITPR2,NPAS3,SOX5,LSAMP,RORA,EFEMP1,CDH20,SLC1A2,NFIB,NTRK2,SLC1A3,NRXN1,MGAT4C,PARD3B,LIFR,TNIK,PITPNC1,BMPR1B,ATP13A4,GLUD1,ATP1A2,AQP4,GPM6A,FGFR3,PON2,NRG3,CPE,PTPRZ1,NHSL1,NKAIN3,ADCY2,NTM,CLU,FBXL7,ZBTB20,PCDH9,FMN2,SFXN5,PREX2,CTNND2,CSGALNACT1
3.095e-04	-8.08	oesophagus-carcinoma	COSMIC cancer mutations	oesophagus-carcinoma	4269	24	16828	49	ADCY2,FBXL7,NTM,CDH20,NTRK2,PCDH9,TNIK,LIFR,FMN2,PARD3B,ZBTB20,CTNND2,PREX2,ATP13A4,CSGALNACT1,FGFR3,GPM6A,NRG3,MACF1,NFIA,ITPR2,SOX5,PTPRZ1,NHSL1
3.150e-04	-8.06	cellular response to cocaine	biological process	GO:0071314	10	2	18204	49	SLC1A3,SLC1A2
3.150e-04	-8.06	neuronal action potential propagation	biological process	GO:0019227	10	2	18204	49	NTRK2,ATP1A2
3.150e-04	-8.06	action potential propagation	biological process	GO:0098870	10	2	18204	49	NTRK2,ATP1A2
3.190e-04	-8.05	EDTRNSPORT	prints domains	PR00173	7	2	5227	21	SLC1A3,SLC1A2
3.508e-04	-7.96	ADCY5 (adenylate cyclase 5)	protein interactions	111	11	2	19454	50	PRKCA,ADCY2
3.675e-04	-7.91	PLC beta mediated events	REACTOME pathways	R-HSA-112043	47	3	10285	31	PRKCA,ITPR2,ADCY2
3.844e-04	-7.86	L-glutamate import across plasma membrane	biological process	GO:0098712	11	2	18204	49	SLC1A3,SLC1A2
3.844e-04	-7.86	L-aspartate transmembrane transport	biological process	GO:0070778	11	2	18204	49	SLC1A3,SLC1A2
3.906e-04	-7.85	regulation of chondrocyte differentiation	biological process	GO:0032330	53	3	18204	49	SOX5,EFEMP1,BMPR1B
3.912e-04	-7.85	G-protein mediated events	REACTOME pathways	R-HSA-112040	48	3	10285	31	ADCY2,ITPR2,PRKCA
3.918e-04	-7.84	oesophagus-carcinoma-squamous_cell_carcinoma	COSMIC cancer mutations	oesophagus-carcinoma-squamous_cell_carcinoma	6486	31	16828	49	PITPNC1,BMPR1B,ATP13A4,GLUD1,CSGALNACT1,PARD3B,ZBTB20,TNIK,LIFR,PCDH9,FMN2,SFXN5,PREX2,CTNND2,NRXN1,MGAT4C,ADCY2,FBXL7,CPE,PTPRZ1,SOX5,ITPR2,NPAS3,ATP1A2,GPM6A,AQP4,FGFR3,GLIS3,MACF1,NRG3,PRKCA
3.958e-04	-7.83	positive regulation of multicellular organismal process	biological process	GO:0051240	1691	13	18204	49	RORA,SFXN5,ATP1A2,BMPR1B,PRKCA,SOX5,QKI,NTRK2,CLU,ZBTB20,NRXN1,MACF1,PTPRZ1
4.282e-04	-7.76	haematopoietic_and_lymphoid_tissue	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue	14368	49	16828	49	RBMS3,ADCY2,CLU,FBXL7,NTM,CSGALNACT1,ZBTB20,FMN2,PCDH9,PREX2,CTNND2,SFXN5,DTNA,FGFR3,ATP1A2,AQP4,GPM6A,NRG3,PON2,NHSL1,NKAIN3,CPE,PTPRZ1,NFIB,SLC1A2,MGAT4C,SLC1A3,NTRK2,NRXN1,LSAMP,EFEMP1,RORA,CDH20,BMPR1B,ATP13A4,PITPNC1,GLUD1,PARD3B,MSI2,TNIK,LIFR,QKI,NPAS3,NFIA,ITPR2,PRKCA,MACF1,GLIS3,SOX5
4.347e-04	-7.74	amino acid transport	biological process	GO:0006865	132	4	18204	49	NTRK2,SLC1A2,SLC1A3,SFXN5
4.352e-04	-7.74	mouth	COSMIC cancer mutations	mouth	9004	38	16828	49	MGAT4C,NRXN1,SLC1A3,NTRK2,SLC1A2,CLU,FBXL7,CDH20,NTM,ADCY2,LSAMP,EFEMP1,RORA,CSGALNACT1,ATP13A4,PITPNC1,PREX2,CTNND2,SFXN5,PARD3B,ZBTB20,TNIK,FMN2,LIFR,PCDH9,NPAS3,ITPR2,QKI,DTNA,PRKCA,NRG3,MACF1,FGFR3,ATP1A2,GPM6A,NHSL1,SOX5,PTPRZ1
4.404e-04	-7.73	Ig_I-set	interpro domains	IPR013098	132	4	18521	50	FGFR3,NTRK2,NTM,LSAMP
4.605e-04	-7.68	auditory behavior	biological process	GO:0031223	12	2	18204	49	SLC1A3,NRXN1
4.633e-04	-7.68	MAD_homology1_Dwarfin-type	interpro domains	IPR003619	12	2	18521	50	NFIB,NFIA
4.733e-04	-7.66	I-set	pfam domains	PF07679	132	4	17795	49	LSAMP,NTM,FGFR3,NTRK2
4.796e-04	-7.64	neuron projection development	biological process	GO:0031175	693	8	18204	49	PREX2,GPM6A,CTNND2,BMPR1B,NRXN1,TNIK,NFIB,PTPRZ1
4.817e-04	-7.64	MH1	pfam domains	PF03165	12	2	17795	49	NFIB,NFIA
5.060e-04	-7.59	cell body	cellular component	GO:0044297	556	7	19108	49	GPM6A,SLC1A3,ATP1A2,NRXN1,BMPR1B,CTNND2,SLC1A2
5.187e-04	-7.56	cell junction organization	biological process	GO:0034330	532	7	18204	49	NRXN1,GPM6A,CTNND2,NRG3,CDH20,PRKCA,NFIA
5.284e-04	-7.55	eye development	biological process	GO:0001654	381	6	18204	49	GPM6A,BMPR1B,NFIB,NFIA,EFEMP1,NTRK2
5.359e-04	-7.53	endochondral bone morphogenesis	biological process	GO:0060350	59	3	18204	49	BMPR1B,CSGALNACT1,FGFR3
5.428e-04	-7.52	neurotransmitter transport	biological process	GO:0006836	140	4	18204	49	NRXN1,ATP1A2,SLC1A2,SLC1A3
5.432e-04	-7.52	glial cell fate commitment	biological process	GO:0021781	13	2	18204	49	NFIA,NFIB
5.442e-04	-7.52	NAKATPASE	prints domains	PR00121	9	2	5227	21	ATP13A4,ATP1A2
5.545e-04	-7.50	breast-carcinoma-ductolobular_carcinoma	COSMIC cancer mutations	breast-carcinoma-ductolobular_carcinoma	1619	13	16828	49	DTNA,QKI,RORA,FGFR3,CDH20,MACF1,FMN2,LIFR,PARD3B,CPE,PTPRZ1,CTNND2,PREX2
5.545e-04	-7.50	ductolobular_carcinoma	COSMIC cancer mutations	ductolobular_carcinoma	1619	13	16828	49	MACF1,CDH20,FGFR3,RORA,QKI,DTNA,CTNND2,PREX2,PTPRZ1,CPE,FMN2,LIFR,PARD3B
5.583e-04	-7.49	visual system development	biological process	GO:0150063	385	6	18204	49	BMPR1B,GPM6A,NTRK2,EFEMP1,NFIB,NFIA
5.776e-04	-7.46	PLXNA4 (plexin A4)	protein interactions	91584	14	2	19454	50	CLU,GPM6A
5.789e-04	-7.45	GSE1 (Gse1 coiled-coil protein)	protein interactions	23199	149	4	19454	50	NFIB,TNIK,NFIA,SOX5
5.915e-04	-7.43	upper_aerodigestive_tract-mouth-carcinoma-squamous_cell_carcinoma	COSMIC cancer mutations	upper_aerodigestive_tract-mouth-carcinoma-squamous_cell_carcinoma	6953	32	16828	49	PITPNC1,ATP13A4,CSGALNACT1,TNIK,PCDH9,FMN2,ZBTB20,PARD3B,SFXN5,PREX2,CTNND2,SLC1A2,NRXN1,MGAT4C,RORA,LSAMP,ADCY2,CDH20,NTM,FBXL7,NHSL1,PTPRZ1,SOX5,DTNA,QKI,ITPR2,GPM6A,ATP1A2,FGFR3,MACF1,PRKCA,NRG3
5.937e-04	-7.43	transmembrane receptor protein tyrosine kinase activity	molecular function	GO:0004714	62	3	18094	48	NTRK2,EFEMP1,FGFR3
6.055e-04	-7.41	sensory system development	biological process	GO:0048880	391	6	18204	49	NFIA,NFIB,NTRK2,EFEMP1,GPM6A,BMPR1B
6.145e-04	-7.39	L-glutamate transmembrane transporter activity	molecular function	GO:0005313	14	2	18094	48	SLC1A3,SLC1A2
6.327e-04	-7.37	mechanosensory behavior	biological process	GO:0007638	14	2	18204	49	NRXN1,SLC1A3
6.356e-04	-7.36	adult behavior	biological process	GO:0030534	146	4	18204	49	PREX2,SLC1A2,ATP1A2,NRXN1
6.401e-04	-7.35	brain development	biological process	GO:0007420	724	8	18204	49	NFIB,NRG3,NTRK2,ATP1A2,SLC1A2,RORA,GLUD1,PCDH9
6.412e-04	-7.35	cell adhesion molecule binding	molecular function	GO:0050839	560	7	18094	48	CPE,PRKCA,MACF1,CTNND2,CDH20,PTPRZ1,NRXN1
6.654e-04	-7.32	RNASE13 (ribonuclease A family member 13 (inactive))	protein interactions	440163	15	2	19454	50	CPE,CLU
6.865e-04	-7.28	cell differentiation	biological process	GO:0030154	3645	20	18204	49	PTPRZ1,NFIB,NRXN1,MSI2,PREX2,GPM6A,SLC1A3,FMN2,NTRK2,NTM,CLU,NFIA,TNIK,QKI,SOX5,NHSL1,BMPR1B,RORA,CTNND2,FGFR3
6.941e-04	-7.27	cellular developmental process	biological process	GO:0048869	3648	20	18204	49	BMPR1B,RORA,FGFR3,CTNND2,NTRK2,FMN2,NTM,CLU,NFIA,TNIK,NHSL1,QKI,SOX5,NRXN1,SLC1A3,GPM6A,MSI2,PREX2,PTPRZ1,NFIB
7.288e-04	-7.22	exit from mitosis	biological process	GO:0010458	15	2	18204	49	NFIB,NFIA
7.564e-04	-7.19	forebrain development	biological process	GO:0030900	408	6	18204	49	PCDH9,ATP1A2,SLC1A2,NRG3,NTRK2,NFIB
7.592e-04	-7.18	CNTNAP2 (contactin associated protein 2)	protein interactions	26047	16	2	19454	50	MACF1,CPE
7.640e-04	-7.18	central_nervous_system-brain-glioma-oligodendroglioma_Grade_III	COSMIC cancer mutations	central_nervous_system-brain-glioma-oligodendroglioma_Grade_III	249	5	16828	49	MGAT4C,GLIS3,MACF1,PTPRZ1,FGFR3
7.779e-04	-7.16	small_intestine	COSMIC cancer mutations	small_intestine	250	5	16828	49	TNIK,FGFR3,MACF1,MGAT4C,CSGALNACT1
7.927e-04	-7.14	HYOU1 (hypoxia up-regulated 1)	protein interactions	10525	284	5	19454	50	CLU,EFEMP1,PRKCA,FGFR3,CPE
8.086e-04	-7.12	human chr3q13.31	chromosome location	human chr3q13.31	22	2	26134	50	ZBTB20,LSAMP
8.340e-04	-7.09	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-plasma_cell_myeloma	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-plasma_cell_myeloma	1263	11	16828	49	ATP13A4,NTRK2,FGFR3,ADCY2,GPM6A,TNIK,FMN2,NRG3,CTNND2,NTM,MACF1
8.340e-04	-7.09	plasma_cell_myeloma	COSMIC cancer mutations	plasma_cell_myeloma	1263	11	16828	49	NTRK2,MACF1,NTM,NRG3,GPM6A,ADCY2,FGFR3,ATP13A4,CTNND2,FMN2,TNIK
8.516e-04	-7.07	spindle	COSMIC cancer mutations	spindle	386	6	16828	49	PCDH9,CPE,FGFR3,MACF1,CTNND2,PREX2
8.541e-04	-7.07	telencephalon development	biological process	GO:0021537	276	5	18204	49	NRG3,NTRK2,SLC1A2,NFIB,ATP1A2
9.036e-04	-7.01	NGF signalling via TRKA from the plasma membrane	REACTOME pathways	R-HSA-187037	387	6	10285	31	PRKCA,NTRK2,NRG3,ADCY2,FGFR3,ITPR2
9.072e-04	-7.01	prostate	COSMIC cancer mutations	prostate	13883	48	16828	49	SOX5,PRKCA,GLIS3,MACF1,NPAS3,ITPR2,NFIA,QKI,PARD3B,MSI2,LIFR,TNIK,GLUD1,ATP13A4,BMPR1B,PITPNC1,CDH20,LSAMP,EFEMP1,RORA,MGAT4C,SLC1A3,NTRK2,NRXN1,NFIB,SLC1A2,PTPRZ1,CPE,NKAIN3,NHSL1,NRG3,PON2,FGFR3,ATP1A2,AQP4,GPM6A,DTNA,CTNND2,PREX2,SFXN5,ZBTB20,FMN2,PCDH9,CSGALNACT1,CLU,FBXL7,NTM,ADCY2
9.589e-04	-6.95	DWA	smart domains	SM00523	12	2	9717	38	NFIB,NFIA
9.592e-04	-6.95	humerus	COSMIC cancer mutations	humerus	546	7	16828	49	NKAIN3,FMN2,GPM6A,PARD3B,ADCY2,SFXN5,SOX5
9.621e-04	-6.95	dendrite	cellular component	GO:0030425	620	7	19108	49	CTNND2,CLU,NTRK2,ATP1A2,GPM6A,BMPR1B,ADCY2
9.685e-04	-6.94	SP7 (Sp7 transcription factor)	protein interactions	121340	297	5	19454	50	SOX5,NFIA,NFIB,GLUD1,QKI
9.803e-04	-6.93	dendritic tree	cellular component	GO:0097447	622	7	19108	49	GPM6A,ATP1A2,NTRK2,CLU,CTNND2,ADCY2,BMPR1B
9.825e-04	-6.93	signaling	biological process	GO:0023052	4968	24	18204	49	RORA,NFIA,LIFR,PRKCA,FMN2,NTRK2,SLC1A3,PREX2,DTNA,ADCY2,EFEMP1,ITPR2,NRG3,FGFR3,CTNND2,SLC1A2,PITPNC1,ATP1A2,BMPR1B,TNIK,CLU,CPE,NRXN1,MACF1
9.860e-04	-6.92	cell junction assembly	biological process	GO:0034329	285	5	18204	49	NRG3,NRXN1,PRKCA,CDH20,GPM6A
9.890e-04	-6.92	head development	biological process	GO:0060322	774	8	18204	49	PCDH9,GLUD1,RORA,SLC1A2,ATP1A2,NTRK2,NRG3,NFIB
9.985e-04	-6.91	regulation of cartilage development	biological process	GO:0061035	73	3	18204	49	EFEMP1,BMPR1B,SOX5
9.998e-04	-6.91	skin-trunk-malignant_melanoma-nodular	COSMIC cancer mutations	skin-trunk-malignant_melanoma-nodular	1291	11	16828	49	ATP13A4,NPAS3,NTRK2,CPE,ATP1A2,PREX2,CTNND2,MACF1,CDH20,GLIS3,PTPRZ1
1.022e-03	-6.89	Htt (huntingtin)	protein interactions	15194	77	3	19454	50	NTM,GPM6A,LSAMP
1.026e-03	-6.88	acidic amino acid transmembrane transporter activity	molecular function	GO:0015172	18	2	18094	48	SLC1A3,SLC1A2
1.028e-03	-6.88	soft_tissue	COSMIC cancer mutations	soft_tissue	5828	28	16828	49	SLC1A3,NTRK2,SLC1A2,FBXL7,CLU,CDH20,ADCY2,RORA,LSAMP,PREX2,CTNND2,PCDH9,FMN2,PARD3B,NPAS3,ITPR2,NFIA,NRG3,MACF1,GLIS3,PON2,FGFR3,AQP4,GPM6A,NKAIN3,NHSL1,SOX5,PTPRZ1
1.063e-03	-6.85	ATPase_P-typ_cation-transptr_N	interpro domains	IPR004014	18	2	18521	50	ATP1A2,ATP13A4
1.071e-03	-6.84	astrocyte projection	cellular component	GO:0097449	19	2	19108	49	AQP4,SLC1A2
1.105e-03	-6.81	Cation_ATPase_N	pfam domains	PF00690	18	2	17795	49	ATP13A4,ATP1A2
1.118e-03	-6.80	cell communication	biological process	GO:0007154	5010	24	18204	49	ATP1A2,PITPNC1,SLC1A2,CTNND2,FGFR3,BMPR1B,TNIK,CLU,CPE,NRXN1,MACF1,RORA,PRKCA,LIFR,NFIA,NTRK2,FMN2,PREX2,SLC1A3,DTNA,ADCY2,EFEMP1,NRG3,ITPR2
1.137e-03	-6.78	animal organ morphogenesis	biological process	GO:0009887	988	9	18204	49	NFIB,SOX5,EFEMP1,NTRK2,NRG3,CSGALNACT1,CPE,FGFR3,BMPR1B
1.167e-03	-6.75	positive regulation of nervous system development	biological process	GO:0051962	296	5	18204	49	PTPRZ1,NTRK2,NRXN1,MACF1,QKI
1.179e-03	-6.74	cartilage condensation	biological process	GO:0001502	19	2	18204	49	BMPR1B,SOX5
1.194e-03	-6.73	PON1 (paraoxonase 1)	protein interactions	5444	20	2	19454	50	SFXN5,CLU
1.194e-03	-6.73	PDZD2 (PDZ domain containing 2)	protein interactions	23037	20	2	19454	50	NRXN1,CTNND2
1.210e-03	-6.72	dicarboxylic acid transport	biological process	GO:0006835	78	3	18204	49	NTRK2,SLC1A2,SLC1A3
1.261e-03	-6.68	behavior	biological process	GO:0007610	619	7	18204	49	NTRK2,PTPRZ1,NRXN1,SLC1A2,ATP1A2,PREX2,SLC1A3
1.274e-03	-6.67	central nervous system neuron differentiation	biological process	GO:0021953	176	4	18204	49	RORA,NFIB,BMPR1B,NTRK2
1.307e-03	-6.64	positive regulation of chondrocyte differentiation	biological process	GO:0032332	20	2	18204	49	SOX5,BMPR1B
1.307e-03	-6.64	aspartate transmembrane transport	biological process	GO:0015810	20	2	18204	49	SLC1A2,SLC1A3
1.318e-03	-6.63	ovary-carcinoma	COSMIC cancer mutations	ovary-carcinoma	933	9	16828	49	MACF1,PREX2,PRKCA,ATP1A2,TNIK,FGFR3,NTRK2,ITPR2,BMPR1B
1.332e-03	-6.62	mucosal	COSMIC cancer mutations	mucosal	2009	14	16828	49	BMPR1B,ATP13A4,CPE,FMN2,LIFR,PCDH9,PREX2,CTNND2,MGAT4C,FGFR3,EFEMP1,RORA,ATP1A2,NRG3
1.332e-03	-6.62	skin-mucosal-malignant_melanoma	COSMIC cancer mutations	skin-mucosal-malignant_melanoma	2009	14	16828	49	ATP13A4,BMPR1B,LIFR,FMN2,PCDH9,CPE,PREX2,CTNND2,MGAT4C,ATP1A2,EFEMP1,RORA,FGFR3,NRG3
1.346e-03	-6.61	enzyme-linked receptor protein signaling pathway	biological process	GO:0007167	626	7	18204	49	NFIA,LIFR,EFEMP1,NTRK2,NRG3,FGFR3,BMPR1B
1.383e-03	-6.58	trunk	COSMIC cancer mutations	trunk	3554	20	16828	49	MGAT4C,NPAS3,NTRK2,NRXN1,SLC1A3,NRG3,GLIS3,CDH20,MACF1,FGFR3,ATP1A2,LSAMP,ATP13A4,SOX5,CTNND2,PREX2,PTPRZ1,CPE,PCDH9,LIFR
1.443e-03	-6.54	cell aggregation	biological process	GO:0098743	21	2	18204	49	BMPR1B,SOX5
1.455e-03	-6.53	ZNF608 (zinc finger protein 608)	protein interactions	57507	87	3	19454	50	NFIA,NFIB,SOX5
1.459e-03	-6.53	uveal_tract	COSMIC cancer mutations	uveal_tract	587	7	16828	49	PREX2,CTNND2,MACF1,FGFR3,ADCY2,CPE,PCDH9
1.467e-03	-6.52	cellular response to organic cyclic compound	biological process	GO:0071407	464	6	18204	49	ITPR2,RORA,SLC1A2,SLC1A3,ATP1A2,ADCY2
1.499e-03	-6.50	neuronal cell body	cellular component	GO:0043025	489	6	19108	49	GPM6A,ATP1A2,CTNND2,NRXN1,SLC1A3,BMPR1B
1.550e-03	-6.47	oligodendrocyte differentiation	biological process	GO:0048709	85	3	18204	49	CLU,NTRK2,PTPRZ1
1.563e-03	-6.46	haematopoietic_neoplasm	COSMIC cancer mutations	haematopoietic_neoplasm	11082	42	16828	49	NHSL1,NKAIN3,CPE,PTPRZ1,SOX5,DTNA,QKI,ITPR2,NFIA,NPAS3,ATP1A2,FGFR3,PON2,GLIS3,MACF1,PRKCA,NRG3,BMPR1B,ATP13A4,CSGALNACT1,PARD3B,MSI2,FMN2,LIFR,TNIK,PCDH9,SFXN5,PREX2,CTNND2,RBMS3,SLC1A2,NFIB,NRXN1,NTRK2,SLC1A3,LSAMP,EFEMP1,RORA,ADCY2,CDH20,NTM,FBXL7
1.582e-03	-6.45	Rbm38 (RNA binding motif protein 38)	protein interactions	56190	23	2	19454	50	MSI2,QKI
1.584e-03	-6.45	intracellular sodium ion homeostasis	biological process	GO:0006883	22	2	18204	49	SLC1A3,ATP1A2
1.594e-03	-6.44	DEP_dom	interpro domains	IPR000591	22	2	18521	50	FMN2,PREX2
1.603e-03	-6.44	transport across blood-brain barrier	biological process	GO:0150104	86	3	18204	49	SLC1A3,ATP1A2,SLC1A2
1.603e-03	-6.44	vascular transport	biological process	GO:0010232	86	3	18204	49	SLC1A3,ATP1A2,SLC1A2
1.628e-03	-6.42	Bile secretion	KEGG pathways	hsa04976	71	3	7161	24	ATP1A2,AQP4,ADCY2
1.628e-03	-6.42	Bile secretion	KEGG pathways	ko04976	71	3	7161	24	AQP4,ADCY2,ATP1A2
1.683e-03	-6.39	amino acid:sodium symporter activity	molecular function	GO:0005283	23	2	18094	48	SLC1A2,SLC1A3
1.687e-03	-6.38	lung-carcinoma-bronchioloalveolar_adenocarcinoma	COSMIC cancer mutations	lung-carcinoma-bronchioloalveolar_adenocarcinoma	778	8	16828	49	BMPR1B,NTRK2,FGFR3,ADCY2,TNIK,SOX5,PRKCA,CTNND2
1.687e-03	-6.38	bronchioloalveolar_adenocarcinoma	COSMIC cancer mutations	bronchioloalveolar_adenocarcinoma	778	8	16828	49	FGFR3,ADCY2,TNIK,CTNND2,PRKCA,SOX5,BMPR1B,NTRK2
1.715e-03	-6.37	human chr17q24.2	chromosome location	human chr17q24.2	32	2	26134	50	PRKCA,PITPNC1
1.726e-03	-6.36	Cation_ATPase_N	smart domains	SM00831	16	2	9717	38	ATP1A2,ATP13A4
1.750e-03	-6.35	eye	COSMIC cancer mutations	eye	606	7	16828	49	MACF1,PREX2,CTNND2,PCDH9,ADCY2,FGFR3,CPE
1.757e-03	-6.34	TIAM1 (TIAM Rac1 associated GEF 1)	protein interactions	7074	201	4	19454	50	PRKCA,ATP1A2,GLUD1,DTNA
1.781e-03	-6.33	ovary-carcinoma-serous_carcinoma	COSMIC cancer mutations	ovary-carcinoma-serous_carcinoma	10710	41	16828	49	CLU,FBXL7,CDH20,NTM,ADCY2,LSAMP,RORA,EFEMP1,MGAT4C,NTRK2,NRXN1,SLC1A3,SLC1A2,PREX2,CTNND2,SFXN5,ZBTB20,PARD3B,MSI2,TNIK,PCDH9,FMN2,LIFR,GLUD1,CSGALNACT1,ATP13A4,BMPR1B,PRKCA,NRG3,GLIS3,MACF1,FGFR3,ATP1A2,NPAS3,ITPR2,QKI,DTNA,SOX5,PTPRZ1,CPE,NHSL1
1.817e-03	-6.31	FOXP4 (forkhead box P4)	protein interactions	116113	94	3	19454	50	NFIA,NFIB,SOX5
1.817e-03	-6.31	GRIN1 (glutamate ionotropic receptor NMDA type subunit 1)	protein interactions	2902	94	3	19454	50	FGFR3,NTRK2,PRKCA
1.826e-03	-6.31	oligodendroglioma_Grade_III	COSMIC cancer mutations	oligodendroglioma_Grade_III	303	5	16828	49	GLIS3,MACF1,PTPRZ1,MGAT4C,FGFR3
1.832e-03	-6.30	P-type ion transporter activity	molecular function	GO:0015662	24	2	18094	48	ATP1A2,ATP13A4
1.832e-03	-6.30	P-type transmembrane transporter activity	molecular function	GO:0140358	24	2	18094	48	ATP1A2,ATP13A4
1.848e-03	-6.29	cell surface	cellular component	GO:0009986	896	8	19108	49	SLC1A3,AQP4,ATP1A2,LIFR,SLC1A2,NRXN1,CLU,FGFR3
1.912e-03	-6.26	SOX2 (SRY-box transcription factor 2)	protein interactions	6657	1342	10	19454	50	NFIA,ITPR2,LSAMP,GLIS3,CLU,SOX5,NFIB,MACF1,QKI,MSI2
1.913e-03	-6.26	human chr9p23-p22.3	chromosome location	human chr9p23-p22.3	1	1	26134	50	NFIB
1.913e-03	-6.26	human chr12q21.31-q21.32	chromosome location	human chr12q21.31-q21.32	1	1	26134	50	MGAT4C
1.913e-03	-6.26	human chr3q26.2-q26.31	chromosome location	human chr3q26.2-q26.31	1	1	26134	50	TNIK
1.956e-03	-6.24	SHC1 events in ERBB2 signaling	REACTOME pathways	R-HSA-1250196	22	2	10285	31	PRKCA,NRG3
1.960e-03	-6.23	synapse organization	biological process	GO:0050808	333	5	18204	49	NRXN1,NRG3,NFIA,GPM6A,CTNND2
2.021e-03	-6.20	skin-face-malignant_melanoma-lentigo_maligna	COSMIC cancer mutations	skin-face-malignant_melanoma-lentigo_maligna	23	2	16828	49	PREX2,FGFR3
2.023e-03	-6.20	ETV7 (ETS variant transcription factor 7)	protein interactions	51513	26	2	19454	50	NFIB,NFIA
2.023e-03	-6.20	NRCAM (neuronal cell adhesion molecule)	protein interactions	4897	26	2	19454	50	GLUD1,MACF1
2.035e-03	-6.20	cation binding	molecular function	GO:0043169	4341	21	18094	48	NRXN1,DTNA,ADCY2,ATP13A4,ATP1A2,RORA,EFEMP1,PON2,PCDH9,GLIS3,CPE,ITPR2,MACF1,MGAT4C,PRKCA,SLC1A2,BMPR1B,SLC1A3,CSGALNACT1,ZBTB20,GLUD1
2.047e-03	-6.19	L-glutamate transmembrane transport	biological process	GO:0015813	25	2	18204	49	SLC1A3,SLC1A2
2.072e-03	-6.18	Opioid Signalling	REACTOME pathways	R-HSA-111885	85	3	10285	31	ADCY2,ITPR2,PRKCA
2.138e-03	-6.15	RNA Polymerase III Transcription Termination	REACTOME pathways	R-HSA-73980	23	2	10285	31	NFIB,NFIA
2.139e-03	-6.15	scalp	COSMIC cancer mutations	scalp	2110	14	16828	49	ATP13A4,SOX5,PREX2,PTPRZ1,FMN2,NFIA,NRXN1,RBMS3,MACF1,NTM,FGFR3,RORA,ATP1A2,LSAMP
2.141e-03	-6.15	skeletal system development	biological process	GO:0001501	500	6	18204	49	BMPR1B,FGFR3,CSGALNACT1,SOX5,NFIB,NFIA
2.181e-03	-6.13	MBNL2 (muscleblind like splicing regulator 2)	protein interactions	10150	27	2	19454	50	MSI2,QKI
2.181e-03	-6.13	HPCAL4 (hippocalcin like 4)	protein interactions	51440	27	2	19454	50	AQP4,GPM6A
2.182e-03	-6.13	ion binding	molecular function	GO:0043167	6007	26	18094	48	NTRK2,SLC1A3,FGFR3,BMPR1B,SLC1A2,MACF1,MGAT4C,PRKCA,ETNPPL,CPE,GLIS3,RORA,ADCY2,DTNA,NRXN1,GLUD1,ZBTB20,TNIK,CSGALNACT1,ITPR2,PCDH9,PON2,EFEMP1,ATP1A2,ATP13A4,PITPNC1
2.214e-03	-6.11	C4-dicarboxylate transport	biological process	GO:0015740	26	2	18204	49	SLC1A2,SLC1A3
2.214e-03	-6.11	regulation of macrophage differentiation	biological process	GO:0045649	26	2	18204	49	PRKCA,QKI
2.226e-03	-6.11	membrane	cellular component	GO:0016020	9220	34	19108	49	PCDH9,CTNND2,ITPR2,NRXN1,GPM6A,LIFR,TNIK,NRG3,PREX2,FGFR3,DTNA,LSAMP,CPE,ADCY2,BMPR1B,NKAIN3,CSGALNACT1,SLC1A3,CLU,PTPRZ1,MACF1,SLC1A2,PON2,ATP1A2,AQP4,SFXN5,NTRK2,PARD3B,MGAT4C,CDH20,ATP13A4,PRKCA,FMN2,NTM
2.255e-03	-6.09	Calcium-transporting ATPase, transmembrane domain	gene3d domains	1.20.1110.10	25	2	14470	41	ATP1A2,ATP13A4
2.287e-03	-6.08	NS-malignant_melanoma	COSMIC cancer mutations	NS-malignant_melanoma	3420	19	16828	49	NRXN1,ITPR2,MGAT4C,GLIS3,MACF1,PRKCA,NRG3,ATP1A2,EFEMP1,ADCY2,FGFR3,PITPNC1,ATP13A4,PTPRZ1,CTNND2,PREX2,PCDH9,LIFR,FMN2
2.319e-03	-6.07	poly(U) RNA binding	molecular function	GO:0008266	27	2	18094	48	RBMS3,MSI2
2.328e-03	-6.06	Glutamate Neurotransmitter Release Cycle	REACTOME pathways	R-HSA-210500	24	2	10285	31	SLC1A2,SLC1A3
2.352e-03	-6.05	animal organ development	biological process	GO:0048513	2846	16	18204	49	GLUD1,PCDH9,GPM6A,CPE,NRG3,EFEMP1,NFIB,BMPR1B,ATP1A2,SLC1A2,FGFR3,RORA,CSGALNACT1,NTRK2,SOX5,NFIA
2.398e-03	-6.03	bone morphogenesis	biological process	GO:0060349	99	3	18204	49	BMPR1B,CSGALNACT1,FGFR3
2.463e-03	-6.01	Aldosterone synthesis and secretion	KEGG pathways	ko04925	82	3	7161	24	PRKCA,ADCY2,ITPR2
2.463e-03	-6.01	Aldosterone synthesis and secretion	KEGG pathways	hsa04925	82	3	7161	24	ITPR2,ADCY2,PRKCA
2.490e-03	-6.00	autonomic_ganglia	COSMIC cancer mutations	autonomic_ganglia	4005	21	16828	49	NTRK2,NFIA,NPAS3,SLC1A2,MACF1,GLIS3,FBXL7,ATP1A2,GPM6A,AQP4,FGFR3,ADCY2,PITPNC1,NHSL1,PTPRZ1,CTNND2,PREX2,PARD3B,PCDH9,TNIK,FMN2
2.564e-03	-5.97	perinuclear endoplasmic reticulum lumen	cellular component	GO:0099020	1	1	19108	49	CLU
2.566e-03	-5.97	positive regulation of oligodendrocyte differentiation	biological process	GO:0048714	28	2	18204	49	PTPRZ1,QKI
2.570e-03	-5.96	Dcaf7 (DDB1 and CUL4 associated factor 7)	protein interactions	71833	1	1	19454	50	BMPR1B
2.570e-03	-5.96	Sh2b1 (SH2B adaptor protein 1)	protein interactions	20399	1	1	19454	50	FGFR3
2.570e-03	-5.96	Lztr1 (leucine-zipper-like transcriptional regulator, 1)	protein interactions	66863	1	1	19454	50	BMPR1B
2.570e-03	-5.96	TAS2R20 (taste 2 receptor member 20)	protein interactions	259295	1	1	19454	50	PRKCA
2.570e-03	-5.96	fgf3.L (fibroblast growth factor 3 L homeolog)	protein interactions	373669	1	1	19454	50	FGFR3
2.570e-03	-5.96	1700006A11Rik (RIKEN cDNA 1700006A11 gene)	protein interactions	71824	1	1	19454	50	BMPR1B
2.570e-03	-5.96	Bdnf (brain derived neurotrophic factor)	protein interactions	12064	1	1	19454	50	NTRK2
2.570e-03	-5.96	Sytl1 (synaptotagmin-like 1)	protein interactions	269589	1	1	19454	50	NRXN1
2.570e-03	-5.96	Dynlt1 (dynein light chain Tctex-type 1)	protein interactions	83462	1	1	19454	50	NTRK2
2.570e-03	-5.96	Isl1 (ISL1 transcription factor, LIM/homeodomain)	protein interactions	16392	1	1	19454	50	GLIS3
2.570e-03	-5.96	fbxw7.L (F-box and WD repeat domain containing 7 L homeolog)	protein interactions	734230	1	1	19454	50	PRKCA
2.570e-03	-5.96	Hipk3 (homeodomain interacting protein kinase 3)	protein interactions	15259	1	1	19454	50	GLIS3
2.570e-03	-5.96	Agtrap (angiotensin II, type I receptor-associated protein)	protein interactions	11610	1	1	19454	50	PITPNC1
2.609e-03	-5.95	Proximal tubule bicarbonate reclamation	KEGG pathways	hsa04964	23	2	7161	24	GLUD1,ATP1A2
2.609e-03	-5.95	Proximal tubule bicarbonate reclamation	KEGG pathways	ko04964	23	2	7161	24	GLUD1,ATP1A2
2.638e-03	-5.94	Signalling by NGF	REACTOME pathways	R-HSA-166520	477	6	10285	31	PRKCA,NTRK2,NRG3,ADCY2,FGFR3,ITPR2
2.645e-03	-5.93	KLF3 (KLF transcription factor 3)	protein interactions	51274	225	4	19454	50	NFIA,NFIB,GLUD1,SOX5
2.653e-03	-5.93	peptidoglycan glycosyltransferase activity	molecular function	GO:0008955	1	1	18094	48	CSGALNACT1
2.653e-03	-5.93	ethanolamine-phosphate phospho-lyase activity	molecular function	GO:0050459	1	1	18094	48	ETNPPL
2.653e-03	-5.93	internal N(7)-methylguanine-containing RNA reader activity	molecular function	GO:0160089	1	1	18094	48	QKI
2.653e-03	-5.93	brain-derived neurotrophic factor receptor activity	molecular function	GO:0060175	1	1	18094	48	NTRK2
2.673e-03	-5.92	amino acid:monoatomic cation symporter activity	molecular function	GO:0005416	29	2	18094	48	SLC1A2,SLC1A3
2.692e-03	-5.92	trans-synaptic signaling by neuropeptide	biological process	GO:0099540	1	1	18204	49	NTRK2
2.692e-03	-5.92	negative regulation of epithelial cell proliferation involved in lung morphogenesis	biological process	GO:2000795	1	1	18204	49	NFIB
2.692e-03	-5.92	negative regulation of calcium:sodium antiporter activity	biological process	GO:1903280	1	1	18204	49	ATP1A2
2.692e-03	-5.92	homologous chromosome movement towards spindle pole in meiosis I anaphase	biological process	GO:0051758	1	1	18204	49	FMN2
2.692e-03	-5.92	trans-synaptic signaling by neuropeptide, modulating synaptic transmission	biological process	GO:0099551	1	1	18204	49	NTRK2
2.692e-03	-5.92	positive regulation of angiotensin-activated signaling pathway	biological process	GO:0110063	1	1	18204	49	PRKCA
2.692e-03	-5.92	chemorepulsion involved in interneuron migration from the subpallium to the cortex	biological process	GO:0021842	1	1	18204	49	NRG3
2.692e-03	-5.92	positive regulation of neurofibrillary tangle assembly	biological process	GO:1902998	1	1	18204	49	CLU
2.692e-03	-5.92	regulation of neuronal signal transduction	biological process	GO:1902847	1	1	18204	49	CLU
2.692e-03	-5.92	directional guidance of interneurons involved in migration from the subpallium to the cortex	biological process	GO:0021840	1	1	18204	49	NRG3
2.692e-03	-5.92	lung ciliated cell differentiation	biological process	GO:0061141	1	1	18204	49	NFIB
2.692e-03	-5.92	olfactory cortex development	biological process	GO:0021989	1	1	18204	49	ATP1A2
2.700e-03	-5.91	Rex2_DEP_1	interpro domains	IPR037367	1	1	18521	50	PREX2
2.700e-03	-5.91	cPKC_alpha	interpro domains	IPR034663	1	1	18521	50	PRKCA
2.700e-03	-5.91	Clusterin_CS	interpro domains	IPR033986	1	1	18521	50	CLU
2.700e-03	-5.91	NTRK2	interpro domains	IPR020455	1	1	18521	50	NTRK2
2.700e-03	-5.91	LIFR_N	interpro domains	IPR040901	1	1	18521	50	LIFR
2.700e-03	-5.91	Quaking_NLS	interpro domains	IPR032367	1	1	18521	50	QKI
2.700e-03	-5.91	RBMS3_RRM2	interpro domains	IPR034406	1	1	18521	50	RBMS3
2.700e-03	-5.91	STAR_dimer	interpro domains	IPR032377	1	1	18521	50	QKI
2.700e-03	-5.91	M14_CPE_CPD	interpro domains	IPR034232	1	1	18521	50	CPE
2.700e-03	-5.91	Clusterin	interpro domains	IPR016016	1	1	18521	50	CLU
2.718e-03	-5.91	NR3C1 (nuclear receptor subfamily 3 group C member 1)	protein interactions	2908	950	8	19454	50	CTNND2,PON2,ADCY2,NFIB,ATP13A4,ZBTB20,NFIA,SLC1A3
2.729e-03	-5.90	Insulin secretion	KEGG pathways	hsa04911	85	3	7161	24	ATP1A2,ADCY2,PRKCA
2.751e-03	-5.90	negative regulation of amyloid-beta formation	biological process	GO:1902430	29	2	18204	49	NTRK2,CLU
2.754e-03	-5.89	Quaking_NLS	pfam domains	PF16551	1	1	17795	49	QKI
2.754e-03	-5.89	STAR_dimer	pfam domains	PF16544	1	1	17795	49	QKI
2.754e-03	-5.89	FGFR3_TM	pfam domains	PF21165	1	1	17795	49	FGFR3
2.754e-03	-5.89	LIFR_N	pfam domains	PF18207	1	1	17795	49	LIFR
2.774e-03	-5.89	testis-germ_cell_tumour-non_seminoma	COSMIC cancer mutations	testis-germ_cell_tumour-non_seminoma	487	6	16828	49	TNIK,FGFR3,BMPR1B,MACF1,NTRK2,PRKCA
2.833e-03	-5.87	-	gene3d domains	6.10.250.1740	1	1	14470	41	FGFR3
2.833e-03	-5.87	-	gene3d domains	1.20.5.4010	1	1	14470	41	QKI
2.853e-03	-5.86	MKRN2 (makorin ring finger protein 2)	protein interactions	23609	380	5	19454	50	MACF1,FGFR3,BMPR1B,PRKCA,NFIB
2.859e-03	-5.86	poly-pyrimidine tract binding	molecular function	GO:0008187	30	2	18094	48	RBMS3,MSI2
2.866e-03	-5.85	beta-catenin binding	molecular function	GO:0008013	107	3	18094	48	CDH20,RORA,CTNND2
2.870e-03	-5.85	SH2B1 (SH2B adaptor protein 1)	protein interactions	25970	31	2	19454	50	NTRK2,FGFR3
2.870e-03	-5.85	AVPR1B (arginine vasopressin receptor 1B)	protein interactions	553	31	2	19454	50	PRKCA,FMN2
2.919e-03	-5.84	non_seminoma	COSMIC cancer mutations	non_seminoma	492	6	16828	49	MACF1,NTRK2,PRKCA,TNIK,BMPR1B,FGFR3
2.942e-03	-5.83	L-glutamate import	biological process	GO:0051938	30	2	18204	49	SLC1A3,SLC1A2
2.952e-03	-5.83	cellular response to endogenous stimulus	biological process	GO:0071495	1135	9	18204	49	NTRK2,ITPR2,NFIA,SOX5,BMPR1B,ATP1A2,SLC1A3,SLC1A2,FGFR3
2.991e-03	-5.81	TBR1 (T-box brain transcription factor 1)	protein interactions	10716	112	3	19454	50	SOX5,NFIA,NFIB
3.012e-03	-5.81	Gap junction	KEGG pathways	hsa04540	88	3	7161	24	PRKCA,ADCY2,ITPR2
3.012e-03	-5.81	Gap junction	KEGG pathways	ko04540	88	3	7161	24	ITPR2,ADCY2,PRKCA
3.014e-03	-5.80	t(4;14) translocations of FGFR3	REACTOME pathways	R-HSA-2033515	1	1	10285	31	FGFR3
3.046e-03	-5.79	HMG20A (high mobility group 20A)	protein interactions	10363	234	4	19454	50	DTNA,NFIB,NFIA,SOX5
3.057e-03	-5.79	NXPH2 (neurexophilin 2)	protein interactions	11249	32	2	19454	50	NRXN1,PCDH9
3.072e-03	-5.79	upper_aerodigestive_tract-pharynx-carcinoma-squamous_cell_carcinoma	COSMIC cancer mutations	upper_aerodigestive_tract-pharynx-carcinoma-squamous_cell_carcinoma	1485	11	16828	49	PTPRZ1,PREX2,FMN2,PCDH9,PARD3B,NPAS3,DTNA,MACF1,NRG3,EFEMP1,FGFR3
3.140e-03	-5.76	replacement ossification	biological process	GO:0036075	31	2	18204	49	CSGALNACT1,FGFR3
3.140e-03	-5.76	negative regulation of amyloid precursor protein catabolic process	biological process	GO:1902992	31	2	18204	49	NTRK2,CLU
3.140e-03	-5.76	endochondral ossification	biological process	GO:0001958	31	2	18204	49	CSGALNACT1,FGFR3
3.144e-03	-5.76	ORF3b (ORF3b protein)	protein interactions	1489670	114	3	19454	50	MACF1,PCDH9,ZBTB20
3.158e-03	-5.76	response to stimulus	biological process	GO:0050896	7803	31	18204	49	TNIK,CLU,FGFR3,PITPNC1,ATP1A2,CTNND2,SLC1A2,BMPR1B,AQP4,MACF1,CPE,ZBTB20,NRXN1,SOX5,NFIA,LIFR,PRKCA,FMN2,NTRK2,RORA,PON2,ADCY2,NFIB,NRG3,ITPR2,RBMS3,EFEMP1,SLC1A3,PREX2,GPM6A,DTNA
3.165e-03	-5.76	Calmodulin induced events	REACTOME pathways	R-HSA-111933	28	2	10285	31	ADCY2,PRKCA
3.165e-03	-5.76	CaM pathway	REACTOME pathways	R-HSA-111997	28	2	10285	31	PRKCA,ADCY2
3.266e-03	-5.72	skeletal system morphogenesis	biological process	GO:0048705	228	4	18204	49	SOX5,FGFR3,CSGALNACT1,BMPR1B
3.282e-03	-5.72	E1-E2_ATPase	pfam domains	PF00122	31	2	17795	49	ATP1A2,ATP13A4
3.336e-03	-5.70	GJA1 (gap junction protein alpha 1)	protein interactions	2697	572	6	19454	50	PRKCA,TNIK,MACF1,ITPR2,PCDH9,DTNA
3.344e-03	-5.70	transepithelial transport	biological process	GO:0070633	32	2	18204	49	SLC1A3,SLC1A2
3.344e-03	-5.70	positive regulation of cartilage development	biological process	GO:0061036	32	2	18204	49	BMPR1B,SOX5
3.353e-03	-5.70	HNRNPL (heterogeneous nuclear ribonucleoprotein L)	protein interactions	3191	1958	12	19454	50	DTNA,BMPR1B,PARD3B,NRG3,FGFR3,PON2,NFIA,ZBTB20,QKI,MSI2,MACF1,NFIB
3.401e-03	-5.68	Protein_kinase_ATP_BS	interpro domains	IPR017441	377	5	18521	50	NTRK2,FGFR3,TNIK,PRKCA,BMPR1B
3.403e-03	-5.68	cell adhesion	biological process	GO:0007155	942	8	18204	49	PCDH9,NRXN1,LSAMP,CTNND2,NTM,CDH20,PRKCA,PARD3B
3.416e-03	-5.68	GnRH signaling pathway	KEGG pathways	ko04912	92	3	7161	24	PRKCA,ITPR2,ADCY2
3.416e-03	-5.68	GnRH signaling pathway	KEGG pathways	hsa04912	92	3	7161	24	ADCY2,ITPR2,PRKCA
3.430e-03	-5.68	lentigo_maligna	COSMIC cancer mutations	lentigo_maligna	30	2	16828	49	PREX2,FGFR3
3.430e-03	-5.68	skin-malignant_melanoma-acral_lentiginous	COSMIC cancer mutations	skin-malignant_melanoma-acral_lentiginous	30	2	16828	49	FGFR3,PREX2
3.447e-03	-5.67	CLUSTERIN_1	prosite domains	PS00492	1	1	12186	42	CLU
3.447e-03	-5.67	CLUSTERIN_2	prosite domains	PS00493	1	1	12186	42	CLU
3.472e-03	-5.66	monoatomic ion transmembrane transporter activity	molecular function	GO:0015075	752	7	18094	48	ITPR2,GPM6A,SLC1A2,ATP13A4,SLC1A3,SFXN5,ATP1A2
3.495e-03	-5.66	Cation_ATPase	pfam domains	PF13246	32	2	17795	49	ATP1A2,ATP13A4
3.565e-03	-5.64	small molecule binding	molecular function	GO:0036094	6197	26	18094	48	RORA,ADCY2,NRXN1,DTNA,ETNPPL,MACF1,PRKCA,MGAT4C,GLIS3,CPE,NTRK2,SLC1A3,SLC1A2,BMPR1B,FGFR3,EFEMP1,ATP1A2,PITPNC1,ATP13A4,ITPR2,PCDH9,PON2,CSGALNACT1,TNIK,GLUD1,ZBTB20
3.590e-03	-5.63	Neuronal System	REACTOME pathways	R-HSA-112316	349	5	10285	31	ADCY2,NRXN1,SLC1A2,PRKCA,SLC1A3
3.621e-03	-5.62	serous_carcinoma	COSMIC cancer mutations	serous_carcinoma	10987	41	16828	49	GLUD1,CSGALNACT1,ATP13A4,BMPR1B,SFXN5,PREX2,CTNND2,ZBTB20,PARD3B,MSI2,PCDH9,TNIK,LIFR,FMN2,SLC1A3,NTRK2,NRXN1,MGAT4C,SLC1A2,CDH20,NTM,CLU,FBXL7,LSAMP,EFEMP1,RORA,ADCY2,NHSL1,PTPRZ1,SOX5,CPE,ITPR2,NPAS3,DTNA,QKI,MACF1,GLIS3,NRG3,PRKCA,ATP1A2,FGFR3
3.629e-03	-5.62	Ca-dependent events	REACTOME pathways	R-HSA-111996	30	2	10285	31	PRKCA,ADCY2
3.649e-03	-5.61	TPRA1 (transmembrane protein adipocyte associated 1)	protein interactions	131601	35	2	19454	50	BMPR1B,ITPR2
3.724e-03	-5.59	Downstream signal transduction	REACTOME pathways	R-HSA-186763	352	5	10285	31	PRKCA,ADCY2,NRG3,FGFR3,ITPR2
3.749e-03	-5.59	NCOR2 (nuclear receptor corepressor 2)	protein interactions	9612	248	4	19454	50	NFIB,NFIA,TNIK,SOX5
3.769e-03	-5.58	negative regulation of amide metabolic process	biological process	GO:0034249	34	2	18204	49	CLU,NTRK2
3.815e-03	-5.57	metal ion binding	molecular function	GO:0046872	4239	20	18094	48	SLC1A3,CSGALNACT1,SLC1A2,BMPR1B,ZBTB20,RORA,EFEMP1,ATP1A2,ADCY2,ATP13A4,NRXN1,DTNA,PRKCA,ITPR2,MGAT4C,MACF1,GLIS3,CPE,PCDH9,PON2
3.858e-03	-5.56	receptor complex	cellular component	GO:0043235	409	5	19108	49	LIFR,FGFR3,NTRK2,BMPR1B,ITPR2
3.878e-03	-5.55	organic acid:sodium symporter activity	molecular function	GO:0005343	35	2	18094	48	SLC1A3,SLC1A2
3.879e-03	-5.55	Transmission across Chemical Synapses	REACTOME pathways	R-HSA-112315	217	4	10285	31	ADCY2,SLC1A2,SLC1A3,PRKCA
3.908e-03	-5.54	DAP12 signaling	REACTOME pathways	R-HSA-2424491	356	5	10285	31	PRKCA,ITPR2,ADCY2,NRG3,FGFR3
3.911e-03	-5.54	DELLA	smart domains	SM01129	1	1	9717	38	MACF1
3.912e-03	-5.54	Ig_sub2	interpro domains	IPR003598	239	4	18521	50	NTRK2,NTM,FGFR3,LSAMP
3.937e-03	-5.54	synapse assembly	biological process	GO:0007416	118	3	18204	49	NRXN1,NRG3,GPM6A
3.967e-03	-5.53	Inflammatory mediator regulation of TRP channels	KEGG pathways	hsa04750	97	3	7161	24	ADCY2,ITPR2,PRKCA
3.967e-03	-5.53	Inflammatory mediator regulation of TRP channels	KEGG pathways	ko04750	97	3	7161	24	ADCY2,ITPR2,PRKCA
3.973e-03	-5.53	Sudden Infant Death Syndrome (SIDS) Susceptibility Pathways	WikiPathways	WP706	162	4	5310	22	NTRK2,RORA,AQP4,SLC1A3
3.978e-03	-5.53	eye-uveal_tract-malignant_melanoma-spindle	COSMIC cancer mutations	eye-uveal_tract-malignant_melanoma-spindle	363	5	16828	49	PREX2,CTNND2,MACF1,CPE,PCDH9
3.990e-03	-5.52	neuron fate specification	biological process	GO:0048665	35	2	18204	49	NFIA,NFIB
4.018e-03	-5.52	AQUAPORIN4	prints domains	PR02016	1	1	5227	21	AQP4
4.018e-03	-5.52	NTKRECEPTOR2	prints domains	PR01941	1	1	5227	21	NTRK2
4.031e-03	-5.51	protein kinase activity	molecular function	GO:0004672	577	6	18094	48	PRKCA,NTRK2,EFEMP1,FGFR3,BMPR1B,TNIK
4.052e-03	-5.51	glial cell projection	cellular component	GO:0097386	37	2	19108	49	SLC1A2,AQP4
4.053e-03	-5.51	pancreas-other-adenoma	COSMIC cancer mutations	pancreas-other-adenoma	224	4	16828	49	PCDH9,BMPR1B,PRKCA,CTNND2
4.071e-03	-5.50	TRNAU1AP (tRNA selenocysteine 1 associated protein 1)	protein interactions	54952	37	2	19454	50	ZBTB20,QKI
4.094e-03	-5.50	transporter activity	molecular function	GO:0005215	1211	9	18094	48	GPM6A,AQP4,SLC1A2,SLC1A3,PITPNC1,ATP13A4,ATP1A2,SFXN5,ITPR2
4.244e-03	-5.46	P_typ_ATPase_HD_dom	interpro domains	IPR044492	36	2	18521	50	ATP1A2,ATP13A4
4.244e-03	-5.46	ATPase_P-typ_P_site	interpro domains	IPR018303	36	2	18521	50	ATP1A2,ATP13A4
4.244e-03	-5.46	P_typ_ATPase	interpro domains	IPR001757	36	2	18521	50	ATP1A2,ATP13A4
4.244e-03	-5.46	ATPase_P-typ_cyto_dom_N	interpro domains	IPR023299	36	2	18521	50	ATP1A2,ATP13A4
4.244e-03	-5.46	ATPase_P-typ_transduc_dom_A_sf	interpro domains	IPR008250	36	2	18521	50	ATP1A2,ATP13A4
4.258e-03	-5.46	PAX9 (paired box 9)	protein interactions	5083	127	3	19454	50	NFIB,NFIA,QKI
4.281e-03	-5.45	positive regulation of neurogenesis	biological process	GO:0050769	246	4	18204	49	MACF1,QKI,NTRK2,PTPRZ1
4.289e-03	-5.45	superficial_spreading	COSMIC cancer mutations	superficial_spreading	1110	9	16828	49	LIFR,FGFR3,ADCY2,MACF1,NTM,CTNND2,PREX2,ATP13A4,MGAT4C
4.290e-03	-5.45	Pcbp1 (poly(rC) binding protein 1)	protein interactions	23983	38	2	19454	50	QKI,MSI2
4.297e-03	-5.45	Signaling by EGFR	REACTOME pathways	R-HSA-177929	364	5	10285	31	PRKCA,FGFR3,NRG3,ADCY2,ITPR2
4.335e-03	-5.44	kidney-other-neoplasm	COSMIC cancer mutations	kidney-other-neoplasm	10653	40	16828	49	CLU,FBXL7,CDH20,ADCY2,LSAMP,EFEMP1,RORA,MGAT4C,NTRK2,NRXN1,SLC1A3,NFIB,SLC1A2,PREX2,CTNND2,SFXN5,ZBTB20,TNIK,PCDH9,FMN2,CSGALNACT1,GLUD1,ATP13A4,PRKCA,NRG3,PON2,MACF1,FGFR3,ATP1A2,GPM6A,AQP4,NPAS3,ITPR2,QKI,DTNA,SOX5,PTPRZ1,CPE,NKAIN3,NHSL1
4.391e-03	-5.43	central_nervous_system-parietal_lobe-glioma-astrocytoma_Grade_I	COSMIC cancer mutations	central_nervous_system-parietal_lobe-glioma-astrocytoma_Grade_I	34	2	16828	49	QKI,FGFR3
4.414e-03	-5.42	Integration of energy metabolism	REACTOME pathways	R-HSA-163685	111	3	10285	31	PRKCA,ADCY2,ITPR2
4.432e-03	-5.42	chondroitin biosynthesis	BIOCYC pathways	HUMAN_PWY-6566	2	1	902	2	CSGALNACT1
4.445e-03	-5.42	Retrograde endocannabinoid signaling	KEGG pathways	ko04723	101	3	7161	24	PRKCA,ADCY2,ITPR2
4.445e-03	-5.42	Retrograde endocannabinoid signaling	KEGG pathways	hsa04723	101	3	7161	24	ADCY2,ITPR2,PRKCA
4.448e-03	-5.42	central_nervous_system-brainstem-glioma-oligoastrocytoma_Grade_III	COSMIC cancer mutations	central_nervous_system-brainstem-glioma-oligoastrocytoma_Grade_III	114	3	16828	49	PREX2,SOX5,SLC1A2
4.478e-03	-5.41	ATPase_P-typ_TM_dom_sf	interpro domains	IPR023298	37	2	18521	50	ATP1A2,ATP13A4
4.491e-03	-5.41	sensory organ development	biological process	GO:0007423	581	6	18204	49	GPM6A,BMPR1B,NFIA,NFIB,NTRK2,EFEMP1
4.630e-03	-5.38	adenoid_cystic_carcinoma	COSMIC cancer mutations	adenoid_cystic_carcinoma	1123	9	16828	49	CTNND2,PRKCA,FGFR3,LIFR,RORA,TNIK,MGAT4C,NTRK2,NFIB
4.643e-03	-5.37	Calcium-transporting ATPase, cytoplasmic transduction domain A	gene3d domains	2.70.150.10	36	2	14470	41	ATP13A4,ATP1A2
4.643e-03	-5.37	Calcium-transporting ATPase, cytoplasmic domain N	gene3d domains	3.40.1110.10	36	2	14470	41	ATP13A4,ATP1A2
4.643e-03	-5.37	ZNF609 (zinc finger protein 609)	protein interactions	23060	131	3	19454	50	SOX5,NFIA,NFIB
4.643e-03	-5.37	TRPS1 (transcriptional repressor GATA binding 1)	protein interactions	7227	131	3	19454	50	SOX5,NFIA,NFIB
4.659e-03	-5.37	DAP12 interactions	REACTOME pathways	R-HSA-2172127	371	5	10285	31	ITPR2,FGFR3,ADCY2,NRG3,PRKCA
4.691e-03	-5.36	amino acid import across plasma membrane	biological process	GO:0089718	38	2	18204	49	SLC1A2,SLC1A3
4.705e-03	-5.36	plasma membrane region	cellular component	GO:0098590	1278	9	19108	49	SLC1A3,TNIK,AQP4,GPM6A,ATP1A2,PARD3B,SLC1A2,NRXN1,MACF1
4.805e-03	-5.34	POMK (protein O-mannose kinase)	protein interactions	84197	266	4	19454	50	GLUD1,PON2,BMPR1B,CLU
4.815e-03	-5.34	kidney-Wilms_tumour	COSMIC cancer mutations	kidney-Wilms_tumour	545	6	16828	49	NTRK2,BMPR1B,PRKCA,FGFR3,FMN2,TNIK
4.858e-03	-5.33	Wilms_tumour	COSMIC cancer mutations	Wilms_tumour	546	6	16828	49	FMN2,TNIK,FGFR3,BMPR1B,NTRK2,PRKCA
4.904e-03	-5.32	phosphorus metabolic process	biological process	GO:0006793	1707	11	18204	49	NTRK2,PRKCA,TNIK,BMPR1B,CSGALNACT1,RORA,ATP1A2,FGFR3,EFEMP1,PTPRZ1,ADCY2
4.912e-03	-5.32	central_nervous_system-thalamus-glioma-astrocytoma_Grade_I	COSMIC cancer mutations	central_nervous_system-thalamus-glioma-astrocytoma_Grade_I	36	2	16828	49	QKI,FGFR3
4.930e-03	-5.31	Signaling by PDGF	REACTOME pathways	R-HSA-186797	376	5	10285	31	ADCY2,NRG3,FGFR3,ITPR2,PRKCA
4.936e-03	-5.31	cellular response to alkaloid	biological process	GO:0071312	39	2	18204	49	SLC1A2,SLC1A3
4.936e-03	-5.31	sodium ion homeostasis	biological process	GO:0055078	39	2	18204	49	SLC1A3,ATP1A2
4.942e-03	-5.31	myelination	biological process	GO:0042552	128	3	18204	49	CLU,NTRK2,QKI
4.945e-03	-5.31	NUFIP1 (nuclear FMR1 interacting protein 1)	protein interactions	26747	134	3	19454	50	CPE,GPM6A,NTM
4.980e-03	-5.30	TAFA2 (TAFA chemokine like family member 2)	protein interactions	338811	41	2	19454	50	CPE,LIFR
4.988e-03	-5.30	upper_aerodigestive_tract-head_neck-carcinoma-adenoid_cystic_carcinoma	COSMIC cancer mutations	upper_aerodigestive_tract-head_neck-carcinoma-adenoid_cystic_carcinoma	383	5	16828	49	NTRK2,PRKCA,TNIK,LIFR,FGFR3
4.988e-03	-5.30	salivary_gland-carcinoma	COSMIC cancer mutations	salivary_gland-carcinoma	383	5	16828	49	LIFR,TNIK,FGFR3,NTRK2,PRKCA
4.988e-03	-5.30	upper_aerodigestive_tract-carcinoma	COSMIC cancer mutations	upper_aerodigestive_tract-carcinoma	383	5	16828	49	NTRK2,PRKCA,LIFR,TNIK,FGFR3
4.988e-03	-5.30	upper_aerodigestive_tract-mouth-carcinoma-adenoid_cystic_carcinoma	COSMIC cancer mutations	upper_aerodigestive_tract-mouth-carcinoma-adenoid_cystic_carcinoma	383	5	16828	49	PRKCA,NTRK2,FGFR3,TNIK,LIFR
4.988e-03	-5.30	upper_aerodigestive_tract-lymph_node-carcinoma-adenoid_cystic_carcinoma	COSMIC cancer mutations	upper_aerodigestive_tract-lymph_node-carcinoma-adenoid_cystic_carcinoma	383	5	16828	49	PRKCA,NTRK2,FGFR3,TNIK,LIFR
5.042e-03	-5.29	testis	COSMIC cancer mutations	testis	733	7	16828	49	BMPR1B,FGFR3,TNIK,PRKCA,PREX2,MACF1,NTRK2
5.049e-03	-5.29	FOXP1 (forkhead box P1)	protein interactions	27086	135	3	19454	50	SOX5,NFIA,NFIB
5.078e-03	-5.28	salivary_gland	COSMIC cancer mutations	salivary_gland	1139	9	16828	49	LIFR,RORA,TNIK,FGFR3,CTNND2,PRKCA,NFIB,NTRK2,MGAT4C
5.134e-03	-5.27	Fkbp1b (FK506 binding protein 1b)	protein interactions	14226	2	1	19454	50	BMPR1B
5.134e-03	-5.27	Fkbp1a (FK506 binding protein 1a)	protein interactions	14225	2	1	19454	50	BMPR1B
5.134e-03	-5.27	Bcr (BCR activator of RhoGEF and GTPase)	protein interactions	110279	2	1	19454	50	BMPR1B
5.134e-03	-5.27	Zmym2 (zinc finger, MYM-type 2)	protein interactions	76007	2	1	19454	50	GLIS3
5.134e-03	-5.27	Grin2c (glutamate ionotropic receptor NMDA type subunit 2C)	protein interactions	24411	2	1	19454	50	PRKCA
5.134e-03	-5.27	numb (numb)	protein interactions	34263	2	1	19454	50	PRKCA
5.134e-03	-5.27	Irf7 (interferon regulatory factor 7)	protein interactions	54123	2	1	19454	50	BMPR1B
5.134e-03	-5.27	Kdm4c (lysine (K)-specific demethylase 4C)	protein interactions	76804	2	1	19454	50	GLIS3
5.134e-03	-5.27	Mknk2 (MAP kinase-interacting serine/threonine kinase 2)	protein interactions	17347	2	1	19454	50	BMPR1B
5.134e-03	-5.27	Sh3kbp1 (SH3-domain kinase binding protein 1)	protein interactions	58194	2	1	19454	50	BMPR1B
5.134e-03	-5.27	Fbxo34 (F-box protein 34)	protein interactions	78938	2	1	19454	50	BMPR1B
5.134e-03	-5.27	Ppp3cc (protein phosphatase 3, catalytic subunit, gamma isoform)	protein interactions	19057	2	1	19454	50	BMPR1B
5.134e-03	-5.27	Klhl1 (kelch-like 1)	protein interactions	93688	2	1	19454	50	BMPR1B
5.134e-03	-5.27	Bmpr2 (bone morphogenetic protein receptor type 2)	protein interactions	12168	2	1	19454	50	BMPR1B
5.160e-03	-5.27	axon ensheathment	biological process	GO:0008366	130	3	18204	49	QKI,CLU,NTRK2
5.160e-03	-5.27	ensheathment of neurons	biological process	GO:0007272	130	3	18204	49	QKI,NTRK2,CLU
5.184e-03	-5.26	central_nervous_system-third_ventricle-glioma-astrocytoma_Grade_I	COSMIC cancer mutations	central_nervous_system-third_ventricle-glioma-astrocytoma_Grade_I	37	2	16828	49	QKI,FGFR3
5.187e-03	-5.26	cyclic purine nucleotide metabolic process	biological process	GO:0052652	40	2	18204	49	ADCY2,RORA
5.220e-03	-5.26	GRIA2 (glutamate ionotropic receptor AMPA type subunit 2)	protein interactions	2891	42	2	19454	50	PRKCA,GPM6A
5.251e-03	-5.25	oligoastrocytoma_Grade_II	COSMIC cancer mutations	oligoastrocytoma_Grade_II	121	3	16828	49	CDH20,DTNA,FGFR3
5.259e-03	-5.25	TBL1X (transducin beta like 1 X-linked)	protein interactions	6907	137	3	19454	50	SOX5,NFIB,NFIA
5.299e-03	-5.24	calcium,diacylglycerol-dependent serine/threonine kinase activity	molecular function	GO:0004698	2	1	18094	48	PRKCA
5.299e-03	-5.24	oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor	molecular function	GO:0016639	2	1	18094	48	GLUD1
5.299e-03	-5.24	glutamate dehydrogenase [NAD(P)+] activity	molecular function	GO:0004353	2	1	18094	48	GLUD1
5.299e-03	-5.24	histone H3T6 kinase activity	molecular function	GO:0035403	2	1	18094	48	PRKCA
5.299e-03	-5.24	leukemia inhibitory factor receptor activity	molecular function	GO:0004923	2	1	18094	48	LIFR
5.299e-03	-5.24	glutamate dehydrogenase (NAD+) activity	molecular function	GO:0004352	2	1	18094	48	GLUD1
5.299e-03	-5.24	glutamate dehydrogenase (NADP+) activity	molecular function	GO:0004354	2	1	18094	48	GLUD1
5.376e-03	-5.23	regulation of neurofibrillary tangle assembly	biological process	GO:1902996	2	1	18204	49	CLU
5.376e-03	-5.23	cell differentiation involved in salivary gland development	biological process	GO:0060689	2	1	18204	49	NFIB
5.376e-03	-5.23	positive regulation of dense core granule biogenesis	biological process	GO:2000707	2	1	18204	49	PRKCA
5.376e-03	-5.23	UDP-glucuronate metabolic process	biological process	GO:0046398	2	1	18204	49	CSGALNACT1
5.376e-03	-5.23	negative regulation of mesenchymal cell proliferation involved in lung development	biological process	GO:2000791	2	1	18204	49	NFIB
5.376e-03	-5.23	myofibroblast contraction	biological process	GO:1990764	2	1	18204	49	QKI
5.376e-03	-5.23	regulation of mesenchymal cell proliferation involved in lung development	biological process	GO:2000790	2	1	18204	49	NFIB
5.376e-03	-5.23	chondroitin sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process	biological process	GO:0050653	2	1	18204	49	CSGALNACT1
5.376e-03	-5.23	fibroblast growth factor receptor apoptotic signaling pathway	biological process	GO:1902178	2	1	18204	49	FGFR3
5.376e-03	-5.23	negative regulation of 3'-UTR-mediated mRNA stabilization	biological process	GO:1905869	2	1	18204	49	QKI
5.392e-03	-5.22	Glu/Leu/Phe/Val/Trp_DH	interpro domains	IPR006095	2	1	18521	50	GLUD1
5.392e-03	-5.22	Glu/Leu/Phe/Val_DH_AS	interpro domains	IPR033524	2	1	18521	50	GLUD1
5.392e-03	-5.22	Par3/HAL_N	interpro domains	IPR021922	2	1	18521	50	PARD3B
5.392e-03	-5.22	Glu/Leu/Phe/Val/Trp_DH_dimer	interpro domains	IPR006097	2	1	18521	50	GLUD1
5.392e-03	-5.22	LIF-R-like_Ig-like	interpro domains	IPR048497	2	1	18521	50	LIFR
5.392e-03	-5.22	Clusterin-like	interpro domains	IPR000753	2	1	18521	50	CLU
5.392e-03	-5.22	Glu/Leu/Phe/Val/Trp_DH_C	interpro domains	IPR006096	2	1	18521	50	GLUD1
5.392e-03	-5.22	LIFR_D2	interpro domains	IPR040817	2	1	18521	50	LIFR
5.392e-03	-5.22	Paraoxonase2	interpro domains	IPR008364	2	1	18521	50	PON2
5.392e-03	-5.22	MSI_RRM2	interpro domains	IPR034126	2	1	18521	50	MSI2
5.392e-03	-5.22	Distrobrevin	interpro domains	IPR017432	2	1	18521	50	DTNA
5.392e-03	-5.22	NAD_bind_Glu_DH	interpro domains	IPR033922	2	1	18521	50	GLUD1
5.392e-03	-5.22	Alpha_CARP_receptor-type	interpro domains	IPR041887	2	1	18521	50	PTPRZ1
5.392e-03	-5.22	Formin_Cappuccino_subfam	interpro domains	IPR001265	2	1	18521	50	FMN2
5.392e-03	-5.22	Clusterin_C	interpro domains	IPR016015	2	1	18521	50	CLU
5.392e-03	-5.22	Clusterin_N	interpro domains	IPR016014	2	1	18521	50	CLU
5.440e-03	-5.21	monoatomic ion transmembrane transport	biological process	GO:0034220	804	7	18204	49	SLC1A2,SFXN5,ATP1A2,SLC1A3,GPM6A,ATP13A4,ITPR2
5.443e-03	-5.21	cyclic nucleotide metabolic process	biological process	GO:0009187	41	2	18204	49	RORA,ADCY2
5.461e-03	-5.21	central_nervous_system-brainstem-glioma-astrocytoma_Grade_I	COSMIC cancer mutations	central_nervous_system-brainstem-glioma-astrocytoma_Grade_I	38	2	16828	49	QKI,FGFR3
5.482e-03	-5.21	autonomic_ganglia-neuroblastoma	COSMIC cancer mutations	autonomic_ganglia-neuroblastoma	3970	20	16828	49	SLC1A2,NPAS3,NTRK2,NFIA,FGFR3,ADCY2,ATP1A2,AQP4,GPM6A,FBXL7,MACF1,GLIS3,PITPNC1,PARD3B,FMN2,TNIK,PCDH9,CTNND2,PREX2,PTPRZ1
5.493e-03	-5.20	PK_Tyr_Ser-Thr	pfam domains	PF07714	130	3	17795	49	FGFR3,NTRK2,BMPR1B
5.498e-03	-5.20	neuroblastoma	COSMIC cancer mutations	neuroblastoma	3971	20	16828	49	FBXL7,GLIS3,MACF1,FGFR3,ADCY2,GPM6A,AQP4,ATP1A2,NPAS3,NFIA,NTRK2,SLC1A2,PREX2,CTNND2,PTPRZ1,TNIK,FMN2,PCDH9,PARD3B,PITPNC1
5.500e-03	-5.20	Clusterin	pfam domains	PF01093	2	1	17795	49	CLU
5.500e-03	-5.20	ELFV_dehydrog	pfam domains	PF00208	2	1	17795	49	GLUD1
5.500e-03	-5.20	Par3_HAL_N_term	pfam domains	PF12053	2	1	17795	49	PARD3B
5.500e-03	-5.20	LIF-R_Ig-like	pfam domains	PF21177	2	1	17795	49	LIFR
5.500e-03	-5.20	ELFV_dehydrog_N	pfam domains	PF02812	2	1	17795	49	GLUD1
5.500e-03	-5.20	LIFR_D2	pfam domains	PF17971	2	1	17795	49	LIFR
5.505e-03	-5.20	acral_lentiginous	COSMIC cancer mutations	acral_lentiginous	745	7	16828	49	CSGALNACT1,ATP13A4,NRG3,PREX2,MACF1,CDH20,FGFR3
5.545e-03	-5.19	neutral L-amino acid transmembrane transporter activity	molecular function	GO:0015175	42	2	18094	48	SLC1A3,SLC1A2
5.547e-03	-5.19	Ser-Thr/Tyr_kinase_cat_dom	interpro domains	IPR001245	133	3	18521	50	FGFR3,NTRK2,BMPR1B
5.585e-03	-5.19	SATB2 (SATB homeobox 2)	protein interactions	23314	140	3	19454	50	NFIB,NFIA,SOX5
5.612e-03	-5.18	growth factor binding	molecular function	GO:0019838	136	3	18094	48	LIFR,NTRK2,FGFR3
5.659e-03	-5.17	-	gene3d domains	1.10.287.140	2	1	14470	41	GLUD1
5.767e-03	-5.16	sarcolemma	cellular component	GO:0042383	142	3	19108	49	ATP1A2,DTNA,AQP4
5.875e-03	-5.14	bone	COSMIC cancer mutations	bone	8157	33	16828	49	ATP13A4,CSGALNACT1,ZBTB20,PARD3B,FMN2,LIFR,PCDH9,TNIK,SFXN5,PREX2,CTNND2,NFIB,SLC1A3,NRXN1,NTRK2,LSAMP,RORA,ADCY2,NKAIN3,CPE,PTPRZ1,SOX5,DTNA,QKI,ITPR2,NPAS3,ATP1A2,GPM6A,FGFR3,PON2,MACF1,GLIS3,NRG3
5.890e-03	-5.13	trans-synaptic signaling	biological process	GO:0099537	431	5	18204	49	NTRK2,DTNA,NRXN1,SLC1A2,SLC1A3
5.890e-03	-5.13	response to wounding	biological process	GO:0009611	431	5	18204	49	MACF1,NFIA,SLC1A2,NFIB,SLC1A3
5.908e-03	-5.13	signal transduction	biological process	GO:0007165	4637	21	18204	49	EFEMP1,ITPR2,NRG3,MACF1,ADCY2,DTNA,CPE,PREX2,FMN2,NTRK2,CLU,LIFR,PRKCA,NFIA,TNIK,BMPR1B,RORA,PITPNC1,ATP1A2,CTNND2,FGFR3
5.922e-03	-5.13	GPM6A (glycoprotein M6A)	protein interactions	2823	143	3	19454	50	NTM,PRKCA,CPE
5.934e-03	-5.13	Cholinergic synapse	KEGG pathways	hsa04725	112	3	7161	24	PRKCA,ADCY2,ITPR2
5.935e-03	-5.13	active monoatomic ion transmembrane transporter activity	molecular function	GO:0022853	274	4	18094	48	ATP1A2,SLC1A2,SLC1A3,ATP13A4
5.997e-03	-5.12	FLOT1 (flotillin 1)	protein interactions	10211	453	5	19454	50	GLUD1,SOX5,MACF1,FMN2,DTNA
6.107e-03	-5.10	axon	cellular component	GO:0030424	650	6	19108	49	GPM6A,NFIB,NTRK2,PCDH9,SLC1A2,DTNA
6.108e-03	-5.10	LCK (LCK proto-oncogene, Src family tyrosine kinase)	protein interactions	3932	455	5	19454	50	PRKCA,DTNA,CTNND2,FMN2,MACF1
6.127e-03	-5.10	cell-cell signaling	biological process	GO:0007267	822	7	18204	49	NTRK2,NRXN1,DTNA,SLC1A3,SLC1A2,CPE,FGFR3
6.141e-03	-5.09	metal ion transmembrane transporter activity	molecular function	GO:0046873	442	5	18094	48	GPM6A,SLC1A2,SLC1A3,ATP1A2,ITPR2
6.159e-03	-5.09	monoatomic cation transmembrane transporter activity	molecular function	GO:0008324	630	6	18094	48	GPM6A,SLC1A2,ATP13A4,SLC1A3,ATP1A2,ITPR2
6.164e-03	-5.09	GSK3A (glycogen synthase kinase 3 alpha)	protein interactions	2931	456	5	19454	50	TNIK,NHSL1,PRKCA,GLUD1,MACF1
6.211e-03	-5.08	adrenal_gland	COSMIC cancer mutations	adrenal_gland	2628	15	16828	49	SLC1A2,NTRK2,ATP1A2,EFEMP1,ADCY2,FGFR3,NRG3,NHSL1,CSGALNACT1,ZBTB20,PCDH9,FMN2,PTPRZ1,CTNND2,SOX5
6.234e-03	-5.08	EXTL2 (exostosin like glycosyltransferase 2)	protein interactions	2135	46	2	19454	50	CLU,MGAT4C
6.272e-03	-5.07	DSCR9 (Down syndrome critical region 9)	protein interactions	257203	146	3	19454	50	MACF1,CLU,EFEMP1
6.324e-03	-5.06	protein tyrosine kinase activity	molecular function	GO:0004713	142	3	18094	48	FGFR3,EFEMP1,NTRK2
6.372e-03	-5.06	acute_myeloid_leukaemia	COSMIC cancer mutations	acute_myeloid_leukaemia	10418	39	16828	49	CSGALNACT1,ATP13A4,PREX2,CTNND2,SFXN5,FMN2,PCDH9,TNIK,LIFR,MSI2,PARD3B,NTRK2,NRXN1,SLC1A3,NFIB,SLC1A2,RBMS3,FBXL7,CDH20,NTM,ADCY2,EFEMP1,RORA,LSAMP,NKAIN3,NHSL1,SOX5,PTPRZ1,CPE,NPAS3,NFIA,ITPR2,QKI,NRG3,PRKCA,MACF1,GLIS3,PON2,ATP1A2
6.372e-03	-5.06	haematopoietic_and_lymphoid_tissue-haematopoietic_neoplasm-acute_myeloid_leukaemia	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue-haematopoietic_neoplasm-acute_myeloid_leukaemia	10418	39	16828	49	MSI2,PARD3B,LIFR,PCDH9,TNIK,FMN2,PREX2,CTNND2,SFXN5,ATP13A4,CSGALNACT1,ADCY2,LSAMP,RORA,EFEMP1,FBXL7,CDH20,NTM,NFIB,RBMS3,SLC1A2,NRXN1,NTRK2,SLC1A3,CPE,SOX5,PTPRZ1,NHSL1,NKAIN3,ATP1A2,NRG3,PRKCA,PON2,GLIS3,MACF1,QKI,NPAS3,NFIA,ITPR2
6.401e-03	-5.05	positive regulation of biological process	biological process	GO:0048518	6326	26	18204	49	NPAS3,MACF1,ZBTB20,NRXN1,GLIS3,CLU,TNIK,BMPR1B,FGFR3,ATP1A2,SFXN5,SLC1A2,RBMS3,PTPRZ1,NFIB,GLUD1,GPM6A,SLC1A3,NTRK2,FMN2,NFIA,PRKCA,LIFR,QKI,SOX5,RORA
6.414e-03	-5.05	learning or memory	biological process	GO:0007611	276	4	18204	49	ATP1A2,NTRK2,PTPRZ1,NRXN1
6.493e-03	-5.04	spleen	COSMIC cancer mutations	spleen	408	5	16828	49	PARD3B,TNIK,ADCY2,PTPRZ1,NTM
6.500e-03	-5.04	CNTN1 (contactin 1)	protein interactions	1272	47	2	19454	50	GPM6A,PTPRZ1
6.500e-03	-5.04	BDNF (brain derived neurotrophic factor)	protein interactions	627	47	2	19454	50	CPE,NTRK2
6.512e-03	-5.03	ATXN1L (ataxin 1 like)	protein interactions	342371	148	3	19454	50	NFIB,NFIA,SOX5
6.634e-03	-5.02	KMT2D (lysine methyltransferase 2D)	protein interactions	8085	149	3	19454	50	NFIB,NFIA,SOX5
6.675e-03	-5.01	Aldosterone-regulated sodium reabsorption	KEGG pathways	hsa04960	37	2	7161	24	PRKCA,ATP1A2
6.675e-03	-5.01	Aldosterone-regulated sodium reabsorption	KEGG pathways	ko04960	37	2	7161	24	ATP1A2,PRKCA
6.701e-03	-5.01	RNA Polymerase III Transcription	REACTOME pathways	R-HSA-74158	41	2	10285	31	NFIA,NFIB
6.701e-03	-5.01	RNA Polymerase III Abortive And Retractive Initiation	REACTOME pathways	R-HSA-749476	41	2	10285	31	NFIB,NFIA
6.757e-03	-5.00	KDM2B (lysine demethylase 2B)	protein interactions	84678	150	3	19454	50	NFIB,NFIA,SOX5
6.783e-03	-4.99	ATPASE_E1_E2	prosite domains	PS00154	36	2	12186	42	ATP1A2,ATP13A4
6.812e-03	-4.99	regulation of oligodendrocyte differentiation	biological process	GO:0048713	46	2	18204	49	QKI,PTPRZ1
6.812e-03	-4.99	positive regulation of glial cell differentiation	biological process	GO:0045687	46	2	18204	49	PTPRZ1,QKI
6.875e-03	-4.98	Ig_3	pfam domains	PF13927	141	3	17795	49	NTM,LSAMP,FGFR3
6.881e-03	-4.98	TNIK (TRAF2 and NCK interacting kinase)	protein interactions	23043	151	3	19454	50	CLU,TNIK,MACF1
6.882e-03	-4.98	GLFV_DEHYDROGENASE	prosite domains	PS00074	2	1	12186	42	GLUD1
6.997e-03	-4.96	Wnt signaling pathway	biological process	GO:0016055	283	4	18204	49	CTNND2,CPE,TNIK,MACF1
7.111e-03	-4.95	mitotic cell cycle phase transition	biological process	GO:0044772	146	3	18204	49	NFIA,FBXL7,NFIB
7.119e-03	-4.94	oligoastrocytoma_Grade_III	COSMIC cancer mutations	oligoastrocytoma_Grade_III	263	4	16828	49	FGFR3,SLC1A2,SOX5,PREX2
7.135e-03	-4.94	SOX6 (SRY-box transcription factor 6)	protein interactions	55553	153	3	19454	50	NFIA,NFIB,SOX5
7.144e-03	-4.94	VEGFR2 mediated cell proliferation	REACTOME pathways	R-HSA-5218921	258	4	10285	31	PRKCA,ITPR2,NRG3,FGFR3
7.203e-03	-4.93	SFN (stratifin)	protein interactions	2810	671	6	19454	50	PARD3B,TNIK,NFIA,NFIB,MACF1,FMN2
7.330e-03	-4.92	ANXA3 (annexin A3)	protein interactions	306	50	2	19454	50	FGFR3,EFEMP1
7.351e-03	-4.91	Vascular smooth muscle contraction	KEGG pathways	ko04270	121	3	7161	24	PRKCA,ADCY2,ITPR2
7.351e-03	-4.91	Vascular smooth muscle contraction	KEGG pathways	hsa04270	121	3	7161	24	PRKCA,ADCY2,ITPR2
7.352e-03	-4.91	Vasopressin regulates renal water homeostasis via Aquaporins	REACTOME pathways	R-HSA-432040	43	2	10285	31	ADCY2,AQP4
7.399e-03	-4.91	regulation of amyloid-beta formation	biological process	GO:1902003	48	2	18204	49	CLU,NTRK2
7.437e-03	-4.90	regulation of nervous system development	biological process	GO:0051960	456	5	18204	49	NRXN1,PTPRZ1,NTRK2,QKI,MACF1
7.572e-03	-4.88	positive regulation of cell development	biological process	GO:0010720	458	5	18204	49	QKI,PRKCA,MACF1,PTPRZ1,NTRK2
7.592e-03	-4.88	third_ventricle	COSMIC cancer mutations	third_ventricle	45	2	16828	49	QKI,FGFR3
7.592e-03	-4.88	enteropathy_type_T_cell_lymphoma	COSMIC cancer mutations	enteropathy_type_T_cell_lymphoma	45	2	16828	49	MGAT4C,MACF1
7.592e-03	-4.88	haematopoietic_and_lymphoid_tissue-small_intestine-lymphoid_neoplasm-enteropathy_type_T_cell_lymphoma	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue-small_intestine-lymphoid_neoplasm-enteropathy_type_T_cell_lymphoma	45	2	16828	49	MGAT4C,MACF1
7.607e-03	-4.88	positive regulation of cellular process	biological process	GO:0048522	5719	24	18204	49	FGFR3,SLC1A2,BMPR1B,TNIK,CLU,GLIS3,ZBTB20,NRXN1,NPAS3,MACF1,RORA,NFIA,LIFR,PRKCA,QKI,SOX5,FMN2,NTRK2,SLC1A3,GPM6A,GLUD1,NFIB,RBMS3,PTPRZ1
7.617e-03	-4.88	LINGO1 (leucine rich repeat and Ig domain containing 1)	protein interactions	84894	51	2	19454	50	NTM,PON2
7.617e-03	-4.88	Ndc80 (NDC80 kinetochore complex component)	protein interactions	67052	51	2	19454	50	MACF1,NHSL1
7.640e-03	-4.87	synaptic signaling	biological process	GO:0099536	459	5	18204	49	SLC1A2,SLC1A3,NRXN1,DTNA,NTRK2
7.674e-03	-4.87	alphav-beta3 integrin-PKCalpha complex	cellular component	GO:0035866	3	1	19108	49	PRKCA
7.691e-03	-4.87	Stk35 (serine/threonine kinase 35)	protein interactions	67333	3	1	19454	50	BMPR1B
7.691e-03	-4.87	QRFPR (pyroglutamylated RFamide peptide receptor)	protein interactions	84109	3	1	19454	50	NTM
7.691e-03	-4.87	Plekhb1 (pleckstrin homology domain containing, family B (evectins) member 1)	protein interactions	27276	3	1	19454	50	BMPR1B
7.691e-03	-4.87	Chn1 (chimerin 1)	protein interactions	108699	3	1	19454	50	BMPR1B
7.691e-03	-4.87	Usp45 (ubiquitin specific petidase 45)	protein interactions	77593	3	1	19454	50	BMPR1B
7.691e-03	-4.87	TULP1 (TUB like protein 1)	protein interactions	7287	3	1	19454	50	NRXN1
7.691e-03	-4.87	IL34 (interleukin 34)	protein interactions	146433	3	1	19454	50	PTPRZ1
7.691e-03	-4.87	Rap2a (RAS related protein 2a)	protein interactions	76108	3	1	19454	50	BMPR1B
7.691e-03	-4.87	Spop (speckle-type BTB/POZ protein)	protein interactions	20747	3	1	19454	50	GLIS3
7.691e-03	-4.87	Smad6 (SMAD family member 6)	protein interactions	17130	3	1	19454	50	BMPR1B
7.691e-03	-4.87	Fbxw5 (F-box and WD-40 domain protein 5)	protein interactions	30839	3	1	19454	50	BMPR1B
7.691e-03	-4.87	Lep (leptin)	protein interactions	16846	3	1	19454	50	CLU
7.691e-03	-4.87	Atg16l1 (autophagy related 16 like 1)	protein interactions	77040	3	1	19454	50	BMPR1B
7.691e-03	-4.87	Grm5 (glutamate metabotropic receptor 5)	protein interactions	24418	3	1	19454	50	PRKCA
7.700e-03	-4.87	astrocytoma_Grade_I	COSMIC cancer mutations	astrocytoma_Grade_I	139	3	16828	49	NRG3,FGFR3,QKI
7.750e-03	-4.86	stomach-carcinoma-diffuse_adenocarcinoma	COSMIC cancer mutations	stomach-carcinoma-diffuse_adenocarcinoma	4383	21	16828	49	FGFR3,ADCY2,ATP1A2,GPM6A,CLU,NRG3,PON2,GLIS3,MACF1,QKI,DTNA,MGAT4C,SLC1A3,FMN2,PCDH9,LIFR,CTNND2,PREX2,SOX5,PTPRZ1,NHSL1
7.750e-03	-4.86	diffuse_adenocarcinoma	COSMIC cancer mutations	diffuse_adenocarcinoma	4383	21	16828	49	SLC1A3,MGAT4C,DTNA,QKI,GLIS3,MACF1,PON2,NRG3,CLU,GPM6A,ATP1A2,FGFR3,ADCY2,NHSL1,PTPRZ1,SOX5,PREX2,CTNND2,LIFR,PCDH9,FMN2
7.806e-03	-4.85	ELFV_dehydrog	smart domains	SM00839	2	1	9717	38	GLUD1
7.806e-03	-4.85	CLb	smart domains	SM00030	2	1	9717	38	CLU
7.806e-03	-4.85	CLa	smart domains	SM00035	2	1	9717	38	CLU
7.938e-03	-4.84	acyl-L-homoserine-lactone lactonohydrolase activity	molecular function	GO:0102007	3	1	18094	48	PON2
7.938e-03	-4.84	glucuronylgalactosylproteoglycan 4-beta-N-acetylgalactosaminyltransferase activity	molecular function	GO:0047237	3	1	18094	48	CSGALNACT1
7.938e-03	-4.84	epidermal growth factor receptor activity	molecular function	GO:0005006	3	1	18094	48	EFEMP1
7.938e-03	-4.84	oncostatin-M receptor activity	molecular function	GO:0004924	3	1	18094	48	LIFR
7.938e-03	-4.84	cysteine transmembrane transporter activity	molecular function	GO:0033229	3	1	18094	48	SLC1A2
7.938e-03	-4.84	lactonohydrolase activity	molecular function	GO:0046573	3	1	18094	48	PON2
7.938e-03	-4.84	inositol 1,4,5-trisphosphate-gated calcium channel activity	molecular function	GO:0005220	3	1	18094	48	ITPR2
7.938e-03	-4.84	alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity	molecular function	GO:0008454	3	1	18094	48	MGAT4C
8.020e-03	-4.83	PARAOXONASE2	prints domains	PR01787	2	1	5227	21	PON2
8.020e-03	-4.83	FORMIN	prints domains	PR00828	2	1	5227	21	FMN2
8.020e-03	-4.83	GLFDHDRGNASE	prints domains	PR00082	2	1	5227	21	GLUD1
8.030e-03	-4.82	Non-integrin membrane-ECM interactions	REACTOME pathways	R-HSA-3000171	45	2	10285	31	PRKCA,NRXN1
8.054e-03	-4.82	regulation of dense core granule biogenesis	biological process	GO:2000705	3	1	18204	49	PRKCA
8.054e-03	-4.82	formin-nucleated actin cable organization	biological process	GO:0110009	3	1	18204	49	FMN2
8.054e-03	-4.82	cysteine transport	biological process	GO:0042883	3	1	18204	49	SLC1A2
8.054e-03	-4.82	protein targeting to lysosome involved in chaperone-mediated autophagy	biological process	GO:0061740	3	1	18204	49	CLU
8.054e-03	-4.82	trans-synaptic signaling by BDNF, modulating synaptic transmission	biological process	GO:0099183	3	1	18204	49	NTRK2
8.054e-03	-4.82	immune complex clearance	biological process	GO:0002434	3	1	18204	49	CLU
8.054e-03	-4.82	mammary placode formation	biological process	GO:0060596	3	1	18204	49	NRG3
8.054e-03	-4.82	UDP-N-acetylgalactosamine metabolic process	biological process	GO:0019276	3	1	18204	49	CSGALNACT1
8.054e-03	-4.82	formin-nucleated actin cable assembly	biological process	GO:0070649	3	1	18204	49	FMN2
8.054e-03	-4.82	meiotic chromosome movement towards spindle pole	biological process	GO:0016344	3	1	18204	49	FMN2
8.054e-03	-4.82	neuroligin clustering involved in postsynaptic membrane assembly	biological process	GO:0097118	3	1	18204	49	NRXN1
8.054e-03	-4.82	regulation of calcium:sodium antiporter activity	biological process	GO:1903279	3	1	18204	49	ATP1A2
8.054e-03	-4.82	cysteine transmembrane transport	biological process	GO:1903712	3	1	18204	49	SLC1A2
8.061e-03	-4.82	chromophobe_renal_cell_carcinoma	COSMIC cancer mutations	chromophobe_renal_cell_carcinoma	430	5	16828	49	FGFR3,BMPR1B,TNIK,PRKCA,NTRK2
8.061e-03	-4.82	kidney-carcinoma-chromophobe_renal_cell_carcinoma	COSMIC cancer mutations	kidney-carcinoma-chromophobe_renal_cell_carcinoma	430	5	16828	49	PRKCA,NTRK2,BMPR1B,FGFR3,TNIK
8.065e-03	-4.82	SOX5 (SRY-box transcription factor 5)	protein interactions	6660	160	3	19454	50	SOX5,NFIB,NFIA
8.078e-03	-4.82	Arylesterase	interpro domains	IPR002640	3	1	18521	50	PON2
8.078e-03	-4.82	InsP3_rcpt	interpro domains	IPR000493	3	1	18521	50	ITPR2
8.078e-03	-4.82	NTRK	interpro domains	IPR020777	3	1	18521	50	NTRK2
8.078e-03	-4.82	NTRK_LRRCT	interpro domains	IPR031635	3	1	18521	50	NTRK2
8.078e-03	-4.82	Myelin_PLP	interpro domains	IPR001614	3	1	18521	50	GPM6A
8.078e-03	-4.82	Neuregulin	interpro domains	IPR040180	3	1	18521	50	NRG3
8.078e-03	-4.82	Protein_kinase_C_a/b/g	interpro domains	IPR014375	3	1	18521	50	PRKCA
8.078e-03	-4.82	Myelin_PLP_CS	interpro domains	IPR018237	3	1	18521	50	GPM6A
8.078e-03	-4.82	ROR_rcpt	interpro domains	IPR003079	3	1	18521	50	RORA
8.078e-03	-4.82	NR_DBD_ROR	interpro domains	IPR044101	3	1	18521	50	RORA
8.088e-03	-4.82	amino acid binding	molecular function	GO:0016597	51	2	18094	48	SLC1A3,GLUD1
8.190e-03	-4.80	C11orf52 (chromosome 11 open reading frame 52)	protein interactions	91894	310	4	19454	50	MACF1,FMN2,DTNA,TNIK
8.230e-03	-4.80	learning	biological process	GO:0007612	154	3	18204	49	NRXN1,NTRK2,ATP1A2
8.238e-03	-4.80	Myelin_PLP	pfam domains	PF01275	3	1	17795	49	GPM6A
8.238e-03	-4.80	SR_plectin_7	pfam domains	PF21097	3	1	17795	49	MACF1
8.238e-03	-4.80	LRRCT_2	pfam domains	PF16920	3	1	17795	49	NTRK2
8.238e-03	-4.80	Arylesterase	pfam domains	PF01731	3	1	17795	49	PON2
8.244e-03	-4.80	transmembrane transporter activity	molecular function	GO:0022857	1110	8	18094	48	ITPR2,SLC1A3,ATP13A4,SLC1A2,AQP4,GPM6A,ATP1A2,SFXN5
8.267e-03	-4.80	carboxylic acid transport	biological process	GO:0046942	297	4	18204	49	NTRK2,SLC1A3,SFXN5,SLC1A2
8.320e-03	-4.79	neuromuscular process controlling balance	biological process	GO:0050885	51	2	18204	49	SLC1A3,NRXN1
8.363e-03	-4.78	organic acid transport	biological process	GO:0015849	298	4	18204	49	NTRK2,SLC1A3,SLC1A2,SFXN5
8.446e-03	-4.77	CATATPASE	prints domains	PR00119	35	2	5227	21	ATP1A2,ATP13A4
8.461e-03	-4.77	anion binding	molecular function	GO:0043168	2412	13	18094	48	GLUD1,TNIK,SLC1A3,FGFR3,BMPR1B,NTRK2,ITPR2,PRKCA,ETNPPL,ATP13A4,ADCY2,PITPNC1,ATP1A2
8.476e-03	-4.77	sodium ion transmembrane transporter activity	molecular function	GO:0015081	158	3	18094	48	ATP1A2,SLC1A2,SLC1A3
8.507e-03	-4.77	TAFA4 (TAFA chemokine like family member 4)	protein interactions	151647	54	2	19454	50	LIFR,ITPR2
8.546e-03	-4.76	acute_lymphoblastic_leukaemia	COSMIC cancer mutations	acute_lymphoblastic_leukaemia	2197	13	16828	49	BMPR1B,PTPRZ1,SOX5,PREX2,TNIK,PARD3B,NFIA,NTRK2,DTNA,PRKCA,ATP1A2,ADCY2,FGFR3
8.675e-03	-4.75	positive regulation of synaptic transmission	biological process	GO:0050806	157	3	18204	49	SLC1A3,NRXN1,NTRK2
8.711e-03	-4.74	skin-hand-lentigo	COSMIC cancer mutations	skin-hand-lentigo	3	1	16828	49	FGFR3
8.711e-03	-4.74	skin-leg-lentigo	COSMIC cancer mutations	skin-leg-lentigo	3	1	16828	49	FGFR3
8.711e-03	-4.74	lentigo	COSMIC cancer mutations	lentigo	3	1	16828	49	FGFR3
8.711e-03	-4.74	urinary_tract-bladder-papilloma	COSMIC cancer mutations	urinary_tract-bladder-papilloma	3	1	16828	49	FGFR3
8.711e-03	-4.74	skin-trunk-lentigo	COSMIC cancer mutations	skin-trunk-lentigo	3	1	16828	49	FGFR3
8.711e-03	-4.74	skin-trunk-other-seborrhoeic_keratosis	COSMIC cancer mutations	skin-trunk-other-seborrhoeic_keratosis	3	1	16828	49	FGFR3
8.711e-03	-4.74	skin-forearm-lentigo	COSMIC cancer mutations	skin-forearm-lentigo	3	1	16828	49	FGFR3
8.711e-03	-4.74	skin-face-lentigo	COSMIC cancer mutations	skin-face-lentigo	3	1	16828	49	FGFR3
8.711e-03	-4.74	skin-lentigo	COSMIC cancer mutations	skin-lentigo	3	1	16828	49	FGFR3
8.711e-03	-4.74	skin-leg-other-seborrhoeic_keratosis	COSMIC cancer mutations	skin-leg-other-seborrhoeic_keratosis	3	1	16828	49	FGFR3
8.712e-03	-4.74	ATPase-coupled monoatomic cation transmembrane transporter activity	molecular function	GO:0019829	53	2	18094	48	ATP13A4,ATP1A2
8.772e-03	-4.74	stomach-carcinoma	COSMIC cancer mutations	stomach-carcinoma	439	5	16828	49	FGFR3,BMPR1B,TNIK,PRKCA,NTRK2
8.962e-03	-4.71	neutral amino acid transport	biological process	GO:0015804	53	2	18204	49	SLC1A3,SLC1A2
8.979e-03	-4.71	cell cycle phase transition	biological process	GO:0044770	159	3	18204	49	NFIA,NFIB,FBXL7
9.098e-03	-4.70	G alpha (z) signalling events	REACTOME pathways	R-HSA-418597	48	2	10285	31	PRKCA,ADCY2
9.125e-03	-4.70	CSTL1 (cystatin like 1)	protein interactions	128817	56	2	19454	50	CLU,CPE
9.142e-03	-4.69	cervix-carcinoma-squamous_cell_carcinoma	COSMIC cancer mutations	cervix-carcinoma-squamous_cell_carcinoma	11789	42	16828	49	LIFR,FMN2,TNIK,PCDH9,ZBTB20,PARD3B,SFXN5,PREX2,CTNND2,PITPNC1,BMPR1B,ATP13A4,GLUD1,CSGALNACT1,RORA,LSAMP,ADCY2,CDH20,NTM,FBXL7,SLC1A2,NTRK2,SLC1A3,NRXN1,MGAT4C,CPE,PTPRZ1,SOX5,NHSL1,GPM6A,ATP1A2,FGFR3,MACF1,GLIS3,PON2,NRG3,PRKCA,DTNA,QKI,NFIA,ITPR2,NPAS3
9.147e-03	-4.69	presynaptic membrane	cellular component	GO:0042734	168	3	19108	49	NRXN1,SLC1A2,GPM6A
9.166e-03	-4.69	PROTEIN_KINASE_ATP	prosite domains	PS00107	377	5	12186	42	FGFR3,NTRK2,BMPR1B,PRKCA,TNIK
9.201e-03	-4.69	phosphotransferase activity, alcohol group as acceptor	molecular function	GO:0016773	686	6	18094	48	PRKCA,NTRK2,EFEMP1,BMPR1B,FGFR3,TNIK
9.227e-03	-4.69	cervix	COSMIC cancer mutations	cervix	11793	42	16828	49	NHSL1,CPE,PTPRZ1,SOX5,DTNA,QKI,ITPR2,NFIA,NPAS3,GPM6A,ATP1A2,FGFR3,GLIS3,MACF1,PON2,PRKCA,NRG3,PITPNC1,BMPR1B,ATP13A4,GLUD1,CSGALNACT1,FMN2,LIFR,PCDH9,TNIK,ZBTB20,PARD3B,SFXN5,PREX2,CTNND2,SLC1A2,NRXN1,NTRK2,SLC1A3,MGAT4C,RORA,LSAMP,ADCY2,CDH20,NTM,FBXL7
9.303e-03	-4.68	Prot_kinase_dom	interpro domains	IPR000719	480	5	18521	50	TNIK,BMPR1B,PRKCA,NTRK2,FGFR3
9.565e-03	-4.65	lung-right_lower_lobe-carcinoma-adenocarcinoma	COSMIC cancer mutations	lung-right_lower_lobe-carcinoma-adenocarcinoma	5692	25	16828	49	NKAIN3,PTPRZ1,SOX5,DTNA,ITPR2,NPAS3,ATP1A2,GPM6A,MACF1,NRG3,ATP13A4,GLUD1,PARD3B,LIFR,FMN2,CTNND2,SLC1A3,NTRK2,MGAT4C,LSAMP,ADCY2,CDH20,NTM,CLU,FBXL7
9.565e-03	-4.65	right_lower_lobe	COSMIC cancer mutations	right_lower_lobe	5692	25	16828	49	CDH20,NTM,FBXL7,CLU,LSAMP,ADCY2,SLC1A3,NTRK2,MGAT4C,CTNND2,LIFR,FMN2,PARD3B,GLUD1,ATP13A4,MACF1,NRG3,GPM6A,ATP1A2,ITPR2,NPAS3,DTNA,PTPRZ1,SOX5,NKAIN3
9.571e-03	-4.65	LYN (LYN proto-oncogene, Src family tyrosine kinase)	protein interactions	4067	713	6	19454	50	DTNA,FMN2,SLC1A3,MSI2,MACF1,TNIK
9.616e-03	-4.64	lung-carcinoma-squamous_cell_carcinoma	COSMIC cancer mutations	lung-carcinoma-squamous_cell_carcinoma	14664	48	16828	49	DTNA,PON2,NRG3,GPM6A,AQP4,ATP1A2,FGFR3,NKAIN3,NHSL1,PTPRZ1,CPE,NTM,FBXL7,CLU,ADCY2,CSGALNACT1,SFXN5,PREX2,CTNND2,PCDH9,FMN2,ZBTB20,NFIA,ITPR2,NPAS3,QKI,MACF1,GLIS3,PRKCA,SOX5,NRXN1,NTRK2,SLC1A3,MGAT4C,SLC1A2,NFIB,CDH20,EFEMP1,RORA,LSAMP,GLUD1,PITPNC1,BMPR1B,ATP13A4,TNIK,LIFR,PARD3B,MSI2
9.625e-03	-4.64	response to cocaine	biological process	GO:0042220	55	2	18204	49	SLC1A3,SLC1A2
9.625e-03	-4.64	regulation of amyloid precursor protein catabolic process	biological process	GO:1902991	55	2	18204	49	CLU,NTRK2
9.630e-03	-4.64	CTNNA1 (catenin alpha 1)	protein interactions	1495	325	4	19454	50	NHSL1,TNIK,DTNA,MACF1
9.634e-03	-4.64	biliary_tract	COSMIC cancer mutations	biliary_tract	15309	49	16828	49	LIFR,TNIK,MSI2,PARD3B,PITPNC1,BMPR1B,ATP13A4,GLUD1,RORA,EFEMP1,LSAMP,CDH20,SLC1A2,NFIB,NRXN1,NTRK2,SLC1A3,MGAT4C,SOX5,GLIS3,MACF1,PRKCA,QKI,ITPR2,NFIA,NPAS3,PCDH9,FMN2,ZBTB20,SFXN5,CTNND2,PREX2,CSGALNACT1,ADCY2,NTM,FBXL7,CLU,RBMS3,CPE,PTPRZ1,NHSL1,NKAIN3,AQP4,GPM6A,ATP1A2,FGFR3,PON2,NRG3,DTNA
9.725e-03	-4.63	acinar_carcinoma	COSMIC cancer mutations	acinar_carcinoma	1978	12	16828	49	BMPR1B,NHSL1,CSGALNACT1,FMN2,LIFR,ZBTB20,PARD3B,SOX5,CTNND2,PTPRZ1,QKI,ATP1A2
9.725e-03	-4.63	pancreas-carcinoma-acinar_carcinoma	COSMIC cancer mutations	pancreas-carcinoma-acinar_carcinoma	1978	12	16828	49	ATP1A2,QKI,FMN2,LIFR,PARD3B,ZBTB20,SOX5,CTNND2,PTPRZ1,BMPR1B,NHSL1,CSGALNACT1
9.751e-03	-4.63	dendritic spine	cellular component	GO:0043197	172	3	19108	49	GPM6A,ATP1A2,NTRK2
9.763e-03	-4.63	SNAP25 (synaptosome associated protein 25)	protein interactions	6616	58	2	19454	50	GPM6A,PRKCA
9.767e-03	-4.63	negative regulation of neuron apoptotic process	biological process	GO:0043524	164	3	18204	49	NTRK2,PTPRZ1,CLU
9.871e-03	-4.62	cell-cell junction	cellular component	GO:0005911	513	5	19108	49	PARD3B,PCDH9,CTNND2,CDH20,ATP1A2
9.929e-03	-4.61	import across plasma membrane	biological process	GO:0098739	165	3	18204	49	SLC1A2,SLC1A3,ATP1A2
9.962e-03	-4.61	thyroid-carcinoma-medullary_carcinoma	COSMIC cancer mutations	thyroid-carcinoma-medullary_carcinoma	290	4	16828	49	FGFR3,PARD3B,SLC1A2,NRG3
9.962e-03	-4.61	medullary_carcinoma	COSMIC cancer mutations	medullary_carcinoma	290	4	16828	49	NRG3,FGFR3,SLC1A2,PARD3B
1.005e-02	-4.60	organic substance transport	biological process	GO:0071702	1881	11	18204	49	PITPNC1,SLC1A2,SFXN5,CLU,FMN2,NTRK2,QKI,ATP13A4,SLC1A3,CPE,MACF1
1.006e-02	-4.60	neuron spine	cellular component	GO:0044309	174	3	19108	49	GPM6A,ATP1A2,NTRK2
1.009e-02	-4.60	VEGFA (vascular endothelial growth factor A)	protein interactions	7422	59	2	19454	50	CLU,PTPRZ1
1.009e-02	-4.60	HTATIP2 (HIV-1 Tat interactive protein 2)	protein interactions	10553	59	2	19454	50	PITPNC1,PRKCA
1.017e-02	-4.59	RHOA (ras homolog family member A)	protein interactions	387	1186	8	19454	50	ITPR2,FMN2,PARD3B,PREX2,GLUD1,MACF1,PON2,PRKCA
1.023e-02	-4.58	Neurotransmitter Release Cycle	REACTOME pathways	R-HSA-112310	51	2	10285	31	SLC1A2,SLC1A3
1.023e-02	-4.58	Signaling by ERBB2	REACTOME pathways	R-HSA-1227986	51	2	10285	31	PRKCA,NRG3
1.023e-02	-4.58	positive regulation of cell differentiation	biological process	GO:0045597	906	7	18204	49	BMPR1B,NTRK2,PTPRZ1,PRKCA,MACF1,SOX5,QKI
1.023e-02	-4.58	ovary-carcinoma-mucinous_carcinoma	COSMIC cancer mutations	ovary-carcinoma-mucinous_carcinoma	456	5	16828	49	PRKCA,NTRK2,BMPR1B,FGFR3,TNIK
1.024e-02	-4.58	Dnaja1 (DnaJ heat shock protein family (Hsp40) member A1)	protein interactions	15502	4	1	19454	50	GLIS3
1.024e-02	-4.58	Cdk14 (cyclin dependent kinase 14)	protein interactions	18647	4	1	19454	50	BMPR1B
1.024e-02	-4.58	Rhebl1 (Ras homolog enriched in brain like 1)	protein interactions	69159	4	1	19454	50	BMPR1B
1.024e-02	-4.58	Nme2 (NME/NM23 nucleoside diphosphate kinase 2)	protein interactions	18103	4	1	19454	50	RORA
1.024e-02	-4.58	Nkiras1 (NFKB inhibitor interacting Ras-like protein 1)	protein interactions	69721	4	1	19454	50	BMPR1B
1.024e-02	-4.58	Pick1 (protein interacting with PRKCA 1)	protein interactions	84591	4	1	19454	50	PRKCA
1.024e-02	-4.58	Naa20 (N(alpha)-acetyltransferase 20, NatB catalytic subunit)	protein interactions	67877	4	1	19454	50	BMPR1B
1.024e-02	-4.58	AVPR1A (arginine vasopressin receptor 1A)	protein interactions	552	4	1	19454	50	PRKCA
1.024e-02	-4.58	Ilkap (integrin-linked kinase-associated serine/threonine phosphatase 2C)	protein interactions	67444	4	1	19454	50	BMPR1B
1.024e-02	-4.58	Srgap1 (SLIT-ROBO Rho GTPase activating protein 1)	protein interactions	117600	4	1	19454	50	BMPR1B
1.024e-02	-4.58	Arhgef6 (Rac/Cdc42 guanine nucleotide exchange factor 6)	protein interactions	73341	4	1	19454	50	BMPR1B
1.024e-02	-4.58	CCDC126 (coiled-coil domain containing 126)	protein interactions	90693	4	1	19454	50	GPM6A
1.026e-02	-4.58	kidney-carcinoma-papillary_renal_cell_carcinoma	COSMIC cancer mutations	kidney-carcinoma-papillary_renal_cell_carcinoma	6364	27	16828	49	NFIA,ITPR2,ATP1A2,FGFR3,MACF1,PON2,PRKCA,NRG3,CPE,PTPRZ1,SOX5,NFIB,NTRK2,NRXN1,RORA,ADCY2,NTM,CLU,PITPNC1,BMPR1B,ATP13A4,LIFR,FMN2,TNIK,ZBTB20,CTNND2,PREX2
1.026e-02	-4.58	papillary_renal_cell_carcinoma	COSMIC cancer mutations	papillary_renal_cell_carcinoma	6364	27	16828	49	PREX2,CTNND2,LIFR,FMN2,TNIK,ZBTB20,ATP13A4,BMPR1B,PITPNC1,CLU,NTM,ADCY2,RORA,NRXN1,NTRK2,NFIB,SOX5,PTPRZ1,CPE,NRG3,PRKCA,MACF1,PON2,FGFR3,ATP1A2,NFIA,ITPR2
1.029e-02	-4.58	LHX3 (LIM homeobox 3)	protein interactions	8022	175	3	19454	50	SOX5,NFIA,NFIB
1.030e-02	-4.58	modulation of chemical synaptic transmission	biological process	GO:0050804	494	5	18204	49	NTRK2,NRXN1,NRG3,SLC1A3,ATP1A2
1.030e-02	-4.58	cellular response to growth factor stimulus	biological process	GO:0071363	494	5	18204	49	BMPR1B,NTRK2,NFIA,SOX5,FGFR3
1.030e-02	-4.58	MYELIN_PLP_1	prosite domains	PS00575	3	1	12186	42	GPM6A
1.030e-02	-4.58	MYELIN_PLP_2	prosite domains	PS01004	3	1	12186	42	GPM6A
1.031e-02	-4.57	visual behavior	biological process	GO:0007632	57	2	18204	49	ATP1A2,SLC1A2
1.039e-02	-4.57	regulation of trans-synaptic signaling	biological process	GO:0099177	495	5	18204	49	NRXN1,NRG3,NTRK2,SLC1A3,ATP1A2
1.042e-02	-4.56	mucinous_carcinoma	COSMIC cancer mutations	mucinous_carcinoma	458	5	16828	49	FGFR3,BMPR1B,TNIK,PRKCA,NTRK2
1.042e-02	-4.56	SNTB1 (syntrophin beta 1)	protein interactions	6641	60	2	19454	50	FGFR3,DTNA
1.055e-02	-4.55	cognition	biological process	GO:0050890	319	4	18204	49	NRXN1,NTRK2,PTPRZ1,ATP1A2
1.057e-02	-4.55	brain-derived neurotrophic factor binding	molecular function	GO:0048403	4	1	18094	48	NTRK2
1.057e-02	-4.55	carbon-oxygen lyase activity, acting on phosphates	molecular function	GO:0016838	4	1	18094	48	ETNPPL
1.057e-02	-4.55	ciliary neurotrophic factor receptor activity	molecular function	GO:0004897	4	1	18094	48	LIFR
1.057e-02	-4.55	tricarboxylic acid transmembrane transporter activity	molecular function	GO:0015142	4	1	18094	48	SFXN5
1.057e-02	-4.55	citrate transmembrane transporter activity	molecular function	GO:0015137	4	1	18094	48	SFXN5
1.061e-02	-4.55	GATA3 (GATA binding protein 3)	protein interactions	2625	177	3	19454	50	NFIA,NFIB,QKI
1.062e-02	-4.55	Endocrine and other factor-regulated calcium reabsorption	KEGG pathways	hsa04961	47	2	7161	24	PRKCA,ATP1A2
1.062e-02	-4.55	Endocrine and other factor-regulated calcium reabsorption	KEGG pathways	ko04961	47	2	7161	24	PRKCA,ATP1A2
1.062e-02	-4.55	Aquaporin-mediated transport	REACTOME pathways	R-HSA-445717	52	2	10285	31	AQP4,ADCY2
1.072e-02	-4.54	oncostatin-M-mediated signaling pathway	biological process	GO:0038165	4	1	18204	49	LIFR
1.072e-02	-4.54	positive regulation of mesenchymal stem cell differentiation	biological process	GO:2000741	4	1	18204	49	SOX5
1.072e-02	-4.54	trans-synaptic signaling by BDNF	biological process	GO:0099191	4	1	18204	49	NTRK2
1.072e-02	-4.54	positive regulation of inclusion body assembly	biological process	GO:0090261	4	1	18204	49	CLU
1.072e-02	-4.54	principal sensory nucleus of trigeminal nerve development	biological process	GO:0021740	4	1	18204	49	NFIB
1.072e-02	-4.54	regulation of angiotensin-activated signaling pathway	biological process	GO:0110061	4	1	18204	49	PRKCA
1.072e-02	-4.54	ovarian cumulus expansion	biological process	GO:0001550	4	1	18204	49	BMPR1B
1.072e-02	-4.54	leukemia inhibitory factor signaling pathway	biological process	GO:0048861	4	1	18204	49	LIFR
1.072e-02	-4.54	club cell differentiation	biological process	GO:0060486	4	1	18204	49	NFIB
1.072e-02	-4.54	regulation of amino acid uptake involved in synaptic transmission	biological process	GO:0051941	4	1	18204	49	ATP1A2
1.072e-02	-4.54	response to glycoside	biological process	GO:1903416	4	1	18204	49	ATP1A2
1.072e-02	-4.54	glutamate biosynthetic process	biological process	GO:0006537	4	1	18204	49	GLUD1
1.072e-02	-4.54	brain-derived neurotrophic factor receptor signaling pathway	biological process	GO:0031547	4	1	18204	49	NTRK2
1.072e-02	-4.54	regulation of glutamate uptake involved in transmission of nerve impulse	biological process	GO:0051946	4	1	18204	49	ATP1A2
1.072e-02	-4.54	protein localization to secretory granule	biological process	GO:0033366	4	1	18204	49	CPE
1.072e-02	-4.54	desmosome assembly	biological process	GO:0002159	4	1	18204	49	PRKCA
1.072e-02	-4.54	trigeminal sensory nucleus development	biological process	GO:0021730	4	1	18204	49	NFIB
1.075e-02	-4.53	Signaling pathways regulating pluripotency of stem cells	KEGG pathways	ko04550	139	3	7161	24	BMPR1B,FGFR3,LIFR
1.075e-02	-4.53	Signaling pathways regulating pluripotency of stem cells	KEGG pathways	hsa04550	139	3	7161	24	LIFR,BMPR1B,FGFR3
1.076e-02	-4.53	NHS-like	interpro domains	IPR024845	4	1	18521	50	NHSL1
1.076e-02	-4.53	P5B-type_ATPase	interpro domains	IPR047821	4	1	18521	50	ATP13A4
1.076e-02	-4.53	Na/K-Atpase_Interacting	interpro domains	IPR008516	4	1	18521	50	NKAIN3
1.076e-02	-4.53	P5A-ATPase_N	interpro domains	IPR047819	4	1	18521	50	ATP13A4
1.076e-02	-4.53	PCN-like_spectrin-like_rpt	interpro domains	IPR049538	4	1	18521	50	MACF1
1.076e-02	-4.53	FGF_rcpt_fam	interpro domains	IPR016248	4	1	18521	50	FGFR3
1.076e-02	-4.53	Glyco_transf_54	interpro domains	IPR006759	4	1	18521	50	MGAT4C
1.076e-02	-4.53	Desmoplakin_Spectrin-like	interpro domains	IPR041573	4	1	18521	50	MACF1
1.076e-02	-4.53	PRKG1 (protein kinase cGMP-dependent 1)	protein interactions	5592	61	2	19454	50	TNIK,PRKCA
1.090e-02	-4.52	testis-germ_cell_tumour-seminoma	COSMIC cancer mutations	testis-germ_cell_tumour-seminoma	648	6	16828	49	NTRK2,BMPR1B,PREX2,PRKCA,TNIK,FGFR3
1.092e-02	-4.52	upper_aerodigestive_tract	COSMIC cancer mutations	upper_aerodigestive_tract	13181	45	16828	49	RORA,EFEMP1,LSAMP,CDH20,NFIB,SLC1A2,MGAT4C,NTRK2,NRXN1,SLC1A3,LIFR,TNIK,PARD3B,MSI2,BMPR1B,ATP13A4,PITPNC1,PRKCA,GLIS3,MACF1,QKI,NPAS3,ITPR2,NFIA,SOX5,ADCY2,FBXL7,CLU,NTM,RBMS3,FMN2,PCDH9,ZBTB20,CTNND2,PREX2,SFXN5,CSGALNACT1,FGFR3,GPM6A,ATP1A2,NRG3,DTNA,PTPRZ1,NHSL1,NKAIN3
1.096e-02	-4.51	lung-carcinoma-large_cell_carcinoma	COSMIC cancer mutations	lung-carcinoma-large_cell_carcinoma	849	7	16828	49	BMPR1B,NTRK2,TNIK,LIFR,FGFR3,PTPRZ1,PRKCA
1.096e-02	-4.51	large_cell_carcinoma	COSMIC cancer mutations	large_cell_carcinoma	849	7	16828	49	BMPR1B,NTRK2,LIFR,TNIK,FGFR3,PTPRZ1,PRKCA
1.097e-02	-4.51	Glyco_transf_54	pfam domains	PF04666	4	1	17795	49	MGAT4C
1.097e-02	-4.51	Spectrin_4	pfam domains	PF21020	4	1	17795	49	MACF1
1.097e-02	-4.51	Spectrin_3	pfam domains	PF21019	4	1	17795	49	MACF1
1.097e-02	-4.51	NHS	pfam domains	PF15273	4	1	17795	49	NHSL1
1.097e-02	-4.51	NKAIN	pfam domains	PF05640	4	1	17795	49	NKAIN3
1.097e-02	-4.51	P5-ATPase	pfam domains	PF12409	4	1	17795	49	ATP13A4
1.097e-02	-4.51	Spectrin_2	pfam domains	PF18373	4	1	17795	49	MACF1
1.098e-02	-4.51	ovary-carcinoma-endometrioid_carcinoma	COSMIC cancer mutations	ovary-carcinoma-endometrioid_carcinoma	464	5	16828	49	PRKCA,NTRK2,FGFR3,BMPR1B,TNIK
1.098e-02	-4.51	bone-tibia-Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour	COSMIC cancer mutations	bone-tibia-Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour	649	6	16828	49	NFIB,QKI,TNIK,FGFR3,MACF1,PREX2
1.098e-02	-4.51	primitive_neuroectodermal_tumour-medulloblastoma	COSMIC cancer mutations	primitive_neuroectodermal_tumour-medulloblastoma	15350	49	16828	49	PITPNC1,BMPR1B,ATP13A4,GLUD1,MSI2,PARD3B,TNIK,LIFR,SLC1A2,NFIB,SLC1A3,NRXN1,NTRK2,MGAT4C,LSAMP,EFEMP1,RORA,CDH20,SOX5,QKI,ITPR2,NFIA,NPAS3,GLIS3,MACF1,PRKCA,CSGALNACT1,ZBTB20,PCDH9,FMN2,SFXN5,PREX2,CTNND2,RBMS3,ADCY2,NTM,CLU,FBXL7,NHSL1,NKAIN3,CPE,PTPRZ1,DTNA,ATP1A2,GPM6A,AQP4,FGFR3,PON2,NRG3
1.106e-02	-4.50	chondroitin biosynthesis	BIOCYC pathways	META_PWY-6566	5	1	902	2	CSGALNACT1
1.107e-02	-4.50	inorganic molecular entity transmembrane transporter activity	molecular function	GO:0015318	714	6	18094	48	ITPR2,ATP1A2,SLC1A3,AQP4,SLC1A2,GPM6A
1.108e-02	-4.50	protein phosphorylation	biological process	GO:0006468	503	5	18204	49	PRKCA,TNIK,BMPR1B,NTRK2,EFEMP1
1.110e-02	-4.50	VTN (vitronectin)	protein interactions	7448	180	3	19454	50	PRKCA,GLUD1,NFIA
1.110e-02	-4.50	MYOD1 (myogenic differentiation 1)	protein interactions	4654	180	3	19454	50	NFIA,PRKCA,RORA
1.115e-02	-4.50	plasma membrane bounded cell projection organization	biological process	GO:0120036	1152	8	18204	49	PREX2,GPM6A,CTNND2,NRXN1,BMPR1B,NFIB,TNIK,PTPRZ1
1.118e-02	-4.49	parietal_lobe	COSMIC cancer mutations	parietal_lobe	55	2	16828	49	FGFR3,QKI
1.129e-02	-4.48	-	gene3d domains	1.20.58.1060	4	1	14470	41	MACF1
1.137e-02	-4.48	proteoglycan biosynthetic process	biological process	GO:0030166	60	2	18204	49	BMPR1B,CSGALNACT1
1.137e-02	-4.48	transmission of nerve impulse	biological process	GO:0019226	60	2	18204	49	NTRK2,ATP1A2
1.138e-02	-4.48	lung-carcinoma-small_cell_carcinoma	COSMIC cancer mutations	lung-carcinoma-small_cell_carcinoma	9908	37	16828	49	NFIB,MGAT4C,NRXN1,NTRK2,RORA,CLU,FBXL7,CDH20,NTM,BMPR1B,ATP13A4,PITPNC1,GLUD1,CSGALNACT1,MSI2,PARD3B,PCDH9,LIFR,TNIK,FMN2,CTNND2,PREX2,QKI,DTNA,NPAS3,ITPR2,NFIA,FGFR3,ATP1A2,GPM6A,PRKCA,NRG3,MACF1,NKAIN3,CPE,SOX5,PTPRZ1
1.143e-02	-4.47	human chr4q34.2	chromosome location	human chr4q34.2	6	1	26134	50	GPM6A
1.143e-02	-4.47	human chr14q13.1	chromosome location	human chr14q13.1	6	1	26134	50	NPAS3
1.144e-02	-4.47	NLGN2 (neuroligin 2)	protein interactions	57555	63	2	19454	50	NRXN1,CLU
1.150e-02	-4.47	small_cell_carcinoma	COSMIC cancer mutations	small_cell_carcinoma	9913	37	16828	49	ATP13A4,BMPR1B,PITPNC1,GLUD1,CSGALNACT1,TNIK,LIFR,FMN2,PCDH9,PARD3B,MSI2,PREX2,CTNND2,NFIB,MGAT4C,NRXN1,NTRK2,RORA,FBXL7,CLU,CDH20,NTM,NKAIN3,CPE,SOX5,PTPRZ1,QKI,DTNA,NPAS3,NFIA,ITPR2,FGFR3,GPM6A,ATP1A2,NRG3,PRKCA,MACF1
1.153e-02	-4.46	response to endogenous stimulus	biological process	GO:0009719	1402	9	18204	49	BMPR1B,FGFR3,ATP1A2,SLC1A3,SLC1A2,ITPR2,NTRK2,SOX5,NFIA
1.160e-02	-4.46	skin-face-malignant_melanoma-superficial_spreading	COSMIC cancer mutations	skin-face-malignant_melanoma-superficial_spreading	4	1	16828	49	PREX2
1.160e-02	-4.46	urinary_tract-bladder-other-normal	COSMIC cancer mutations	urinary_tract-bladder-other-normal	4	1	16828	49	FGFR3
1.160e-02	-4.46	skin-benign_melanocytic_nevus-junctional	COSMIC cancer mutations	skin-benign_melanocytic_nevus-junctional	4	1	16828	49	FGFR3
1.160e-02	-4.46	skin-lower_leg-malignant_melanoma-nodular	COSMIC cancer mutations	skin-lower_leg-malignant_melanoma-nodular	4	1	16828	49	PREX2
1.160e-02	-4.46	inverted	COSMIC cancer mutations	inverted	4	1	16828	49	FGFR3
1.160e-02	-4.46	urinary_tract-bladder-papilloma-inverted	COSMIC cancer mutations	urinary_tract-bladder-papilloma-inverted	4	1	16828	49	FGFR3
1.163e-02	-4.45	renal_cell_carcinoma	COSMIC cancer mutations	renal_cell_carcinoma	4535	21	16828	49	BMPR1B,PITPNC1,LIFR,PCDH9,TNIK,MSI2,SOX5,PREX2,CTNND2,PTPRZ1,NFIB,QKI,ITPR2,NTRK2,NRXN1,FGFR3,RORA,FBXL7,PRKCA,CLU,MACF1
1.163e-02	-4.45	kidney-carcinoma-renal_cell_carcinoma	COSMIC cancer mutations	kidney-carcinoma-renal_cell_carcinoma	4535	21	16828	49	PREX2,CTNND2,SOX5,PTPRZ1,MSI2,TNIK,PCDH9,LIFR,BMPR1B,PITPNC1,CLU,FBXL7,PRKCA,MACF1,FGFR3,RORA,NRXN1,NTRK2,ITPR2,NFIB,QKI
1.169e-02	-4.45	PLP	smart domains	SM00002	3	1	9717	38	GPM6A
1.179e-02	-4.44	VSX1 (visual system homeobox 1)	protein interactions	30813	64	2	19454	50	NFIB,NFIA
1.179e-02	-4.44	LIPG (lipase G, endothelial type)	protein interactions	9388	64	2	19454	50	FGFR3,ETNPPL
1.179e-02	-4.44	EVA1C (eva-1 homolog C)	protein interactions	59271	64	2	19454	50	BMPR1B,PCDH9
1.183e-02	-4.44	Adrenergic signaling in cardiomyocytes	KEGG pathways	hsa04261	144	3	7161	24	PRKCA,ATP1A2,ADCY2
1.183e-02	-4.44	Adrenergic signaling in cardiomyocytes	KEGG pathways	ko04261	144	3	7161	24	ATP1A2,ADCY2,PRKCA
1.195e-02	-4.43	ATP2B2 (ATPase plasma membrane Ca2+ transporting 2)	protein interactions	491	185	3	19454	50	CLU,GPM6A,PRKCA
1.197e-02	-4.43	Transferase(Phosphotransferase) domain 1	gene3d domains	1.10.510.10	490	5	14470	41	TNIK,FGFR3,PRKCA,BMPR1B,NTRK2
1.201e-02	-4.42	RORNUCRECPTR	prints domains	PR01293	3	1	5227	21	RORA
1.201e-02	-4.42	MYELINPLP	prints domains	PR00214	3	1	5227	21	GPM6A
1.201e-02	-4.42	NTKRECEPTOR	prints domains	PR01939	3	1	5227	21	NTRK2
1.201e-02	-4.42	INSP3RECEPTR	prints domains	PR00779	3	1	5227	21	ITPR2
1.201e-02	-4.42	PARAOXONASE	prints domains	PR01785	3	1	5227	21	PON2
1.202e-02	-4.42	PTPN11 (protein tyrosine phosphatase non-receptor type 11)	protein interactions	5781	347	4	19454	50	PRKCA,LIFR,NTRK2,FGFR3
1.215e-02	-4.41	HPX (hemopexin)	protein interactions	3263	65	2	19454	50	CLU,GLUD1
1.218e-02	-4.41	positive regulation of cellular component biogenesis	biological process	GO:0044089	515	5	18204	49	PRKCA,GPM6A,NTRK2,NRXN1,CLU
1.221e-02	-4.41	germ_cell_tumour	COSMIC cancer mutations	germ_cell_tumour	867	7	16828	49	TNIK,FGFR3,BMPR1B,MACF1,NTRK2,PRKCA,PREX2
1.224e-02	-4.40	Ion homeostasis	REACTOME pathways	R-HSA-5578775	56	2	10285	31	ATP1A2,ITPR2
1.228e-02	-4.40	ovary-carcinoma-clear_cell_carcinoma	COSMIC cancer mutations	ovary-carcinoma-clear_cell_carcinoma	665	6	16828	49	PRKCA,FGFR3,LIFR,TNIK,NTRK2,BMPR1B
1.230e-02	-4.40	KLF5 (KLF transcription factor 5)	protein interactions	688	187	3	19454	50	CLU,PRKCA,NFIA
1.239e-02	-4.39	Spinal Cord Injury	WikiPathways	WP2431	119	3	5310	22	AQP4,PRKCA,PTPRZ1
1.239e-02	-4.39	adherens junction	cellular component	GO:0005912	188	3	19108	49	PARD3B,CTNND2,CDH20
1.248e-02	-4.38	HNF1B (HNF1 homeobox B)	protein interactions	6928	188	3	19454	50	NFIA,NFIB,SOX5
1.249e-02	-4.38	back	COSMIC cancer mutations	back	310	4	16828	49	FGFR3,ATP1A2,TNIK,PREX2
1.250e-02	-4.38	MICB (MHC class I polypeptide-related sequence B)	protein interactions	4277	66	2	19454	50	CLU,SFXN5
1.250e-02	-4.38	MAML1 (mastermind like transcriptional coactivator 1)	protein interactions	9794	66	2	19454	50	NFIB,NFIA
1.250e-02	-4.38	ORM1 (orosomucoid 1)	protein interactions	5004	66	2	19454	50	GLUD1,CLU
1.262e-02	-4.37	clear_cell_carcinoma	COSMIC cancer mutations	clear_cell_carcinoma	669	6	16828	49	PRKCA,NTRK2,BMPR1B,FGFR3,LIFR,TNIK
1.262e-02	-4.37	Ig-like_fold	interpro domains	IPR013783	721	6	18521	50	FGFR3,PTPRZ1,NTRK2,NTM,LIFR,LSAMP
1.276e-02	-4.36	neurofibrillary tangle	cellular component	GO:0097418	5	1	19108	49	CLU
1.277e-02	-4.36	phosphate-containing compound metabolic process	biological process	GO:0006796	1681	10	18204	49	ADCY2,PRKCA,TNIK,PTPRZ1,EFEMP1,NTRK2,ATP1A2,FGFR3,RORA,BMPR1B
1.279e-02	-4.36	Rab6b (RAB6B, member RAS oncogene family)	protein interactions	270192	5	1	19454	50	BMPR1B
1.279e-02	-4.36	ADCYAP1R1 (ADCYAP receptor type I)	protein interactions	117	5	1	19454	50	CLU
1.279e-02	-4.36	Rhoj (ras homolog family member J)	protein interactions	80837	5	1	19454	50	BMPR1B
1.279e-02	-4.36	Rab38 (RAB38, member RAS oncogene family)	protein interactions	72433	5	1	19454	50	BMPR1B
1.279e-02	-4.36	DLX3 (distal-less homeobox 3)	protein interactions	1747	5	1	19454	50	PRKCA
1.279e-02	-4.36	CFHR3 (complement factor H related 3)	protein interactions	10878	5	1	19454	50	PRKCA
1.279e-02	-4.36	GABRR2 (gamma-aminobutyric acid type A receptor subunit rho2)	protein interactions	2570	5	1	19454	50	PRKCA
1.279e-02	-4.36	EPPIN (epididymal peptidase inhibitor)	protein interactions	57119	5	1	19454	50	CLU
1.279e-02	-4.36	Rhobtb1 (Rho-related BTB domain containing 1)	protein interactions	69288	5	1	19454	50	BMPR1B
1.279e-02	-4.36	Rras2 (related RAS viral (r-ras) oncogene 2)	protein interactions	66922	5	1	19454	50	BMPR1B
1.279e-02	-4.36	Wwp2 (WW domain containing E3 ubiquitin protein ligase 2)	protein interactions	66894	5	1	19454	50	GLIS3
1.279e-02	-4.36	TRH (thyrotropin releasing hormone)	protein interactions	7200	5	1	19454	50	CPE
1.279e-02	-4.36	SUI2 (translation initiation factor eIF2 subunit alpha)	protein interactions	853463	5	1	19454	50	PRKCA
1.279e-02	-4.36	SYT13 (synaptotagmin 13)	protein interactions	57586	5	1	19454	50	NRXN1
1.279e-02	-4.36	Cdk4 (cyclin dependent kinase 4)	protein interactions	12567	5	1	19454	50	BMPR1B
1.281e-02	-4.36	response to organic substance	biological process	GO:0010033	2498	13	18204	49	ITPR2,ADCY2,AQP4,ZBTB20,SLC1A3,NTRK2,CLU,TNIK,LIFR,PRKCA,RORA,ATP1A2,SLC1A2
1.281e-02	-4.36	cell population proliferation	biological process	GO:0008283	726	6	18204	49	SOX5,NFIB,FGFR3,RORA,NFIA,CLU
1.287e-02	-4.35	dendrite morphogenesis	biological process	GO:0048813	64	2	18204	49	PREX2,CTNND2
1.287e-02	-4.35	PARD6A (par-6 family cell polarity regulator alpha)	protein interactions	50855	67	2	19454	50	PRKCA,GLUD1
1.291e-02	-4.35	BCAR1 (BCAR1 scaffold protein, Cas family member)	protein interactions	9564	547	5	19454	50	RBMS3,PON2,FGFR3,FBXL7,ETNPPL
1.296e-02	-4.35	kinase activity	molecular function	GO:0016301	739	6	18094	48	NTRK2,EFEMP1,PRKCA,FGFR3,BMPR1B,TNIK
1.306e-02	-4.34	phosphorylation	biological process	GO:0016310	729	6	18204	49	NTRK2,EFEMP1,BMPR1B,FGFR3,PRKCA,TNIK
1.309e-02	-4.34	Ion transport by P-type ATPases	REACTOME pathways	R-HSA-936837	58	2	10285	31	ATP13A4,ATP1A2
1.313e-02	-4.33	Kinase-like_dom_sf	interpro domains	IPR011009	523	5	18521	50	NTRK2,FGFR3,TNIK,PRKCA,BMPR1B
1.313e-02	-4.33	central_nervous_system-medulla-primitive_neuroectodermal_tumour-medulloblastoma-classic	COSMIC cancer mutations	central_nervous_system-medulla-primitive_neuroectodermal_tumour-medulloblastoma-classic	14773	48	16828	49	NHSL1,PTPRZ1,CPE,DTNA,PON2,NRG3,ATP1A2,AQP4,GPM6A,FGFR3,CSGALNACT1,SFXN5,CTNND2,PREX2,ZBTB20,PCDH9,FMN2,RBMS3,NTM,CLU,FBXL7,ADCY2,SOX5,NFIA,ITPR2,NPAS3,QKI,GLIS3,MACF1,PRKCA,GLUD1,PITPNC1,BMPR1B,ATP13A4,MSI2,PARD3B,LIFR,TNIK,NRXN1,NTRK2,SLC1A3,MGAT4C,SLC1A2,NFIB,CDH20,LSAMP,RORA,EFEMP1
1.313e-02	-4.33	central_nervous_system-medulla-primitive_neuroectodermal_tumour-medulloblastoma-large_cell	COSMIC cancer mutations	central_nervous_system-medulla-primitive_neuroectodermal_tumour-medulloblastoma-large_cell	14773	48	16828	49	LSAMP,EFEMP1,RORA,CDH20,NFIB,SLC1A2,MGAT4C,NRXN1,NTRK2,SLC1A3,MSI2,PARD3B,LIFR,TNIK,BMPR1B,ATP13A4,PITPNC1,GLUD1,PRKCA,MACF1,GLIS3,QKI,NPAS3,NFIA,ITPR2,SOX5,ADCY2,CLU,FBXL7,NTM,RBMS3,ZBTB20,FMN2,PCDH9,CTNND2,PREX2,SFXN5,CSGALNACT1,FGFR3,ATP1A2,GPM6A,AQP4,NRG3,PON2,DTNA,CPE,PTPRZ1,NHSL1
1.313e-02	-4.33	central_nervous_system-medulla-primitive_neuroectodermal_tumour-medulloblastoma	COSMIC cancer mutations	central_nervous_system-medulla-primitive_neuroectodermal_tumour-medulloblastoma	14773	48	16828	49	ZBTB20,FMN2,PCDH9,SFXN5,PREX2,CTNND2,CSGALNACT1,ADCY2,NTM,CLU,FBXL7,RBMS3,CPE,PTPRZ1,NHSL1,ATP1A2,AQP4,GPM6A,FGFR3,PON2,NRG3,DTNA,MSI2,PARD3B,LIFR,TNIK,PITPNC1,BMPR1B,ATP13A4,GLUD1,LSAMP,EFEMP1,RORA,CDH20,SLC1A2,NFIB,SLC1A3,NTRK2,NRXN1,MGAT4C,SOX5,GLIS3,MACF1,PRKCA,QKI,ITPR2,NFIA,NPAS3
1.313e-02	-4.33	central_nervous_system-medulla-primitive_neuroectodermal_tumour-medulloblastoma-desmoplastic	COSMIC cancer mutations	central_nervous_system-medulla-primitive_neuroectodermal_tumour-medulloblastoma-desmoplastic	14773	48	16828	49	DTNA,ATP1A2,GPM6A,AQP4,FGFR3,PON2,NRG3,NHSL1,CPE,PTPRZ1,RBMS3,ADCY2,NTM,CLU,FBXL7,CSGALNACT1,ZBTB20,FMN2,PCDH9,SFXN5,PREX2,CTNND2,QKI,ITPR2,NFIA,NPAS3,GLIS3,MACF1,PRKCA,SOX5,SLC1A2,NFIB,NTRK2,NRXN1,SLC1A3,MGAT4C,LSAMP,EFEMP1,RORA,CDH20,PITPNC1,BMPR1B,ATP13A4,GLUD1,PARD3B,MSI2,LIFR,TNIK
1.314e-02	-4.33	response to growth factor	biological process	GO:0070848	525	5	18204	49	SOX5,FGFR3,NFIA,NTRK2,BMPR1B
1.317e-02	-4.33	classic	COSMIC cancer mutations	classic	14774	48	16828	49	PARD3B,MSI2,TNIK,LIFR,PITPNC1,ATP13A4,BMPR1B,GLUD1,LSAMP,RORA,EFEMP1,CDH20,SLC1A2,NFIB,NRXN1,SLC1A3,NTRK2,MGAT4C,SOX5,MACF1,GLIS3,PRKCA,QKI,NFIA,ITPR2,NPAS3,ZBTB20,FMN2,PCDH9,SFXN5,CTNND2,PREX2,CSGALNACT1,ADCY2,NTM,CLU,FBXL7,RBMS3,CPE,PTPRZ1,NHSL1,ATP1A2,GPM6A,AQP4,FGFR3,PON2,NRG3,DTNA
1.317e-02	-4.33	carboxylic acid transmembrane transporter activity	molecular function	GO:0046943	186	3	18094	48	SLC1A3,SLC1A2,SFXN5
1.320e-02	-4.33	transforming growth factor beta receptor activity, type I	molecular function	GO:0005025	5	1	18094	48	BMPR1B
1.320e-02	-4.33	fibroblast growth factor receptor activity	molecular function	GO:0005007	5	1	18094	48	FGFR3
1.320e-02	-4.33	neuroligin family protein binding	molecular function	GO:0097109	5	1	18094	48	NRXN1
1.320e-02	-4.33	neurotrophin receptor activity	molecular function	GO:0005030	5	1	18094	48	NTRK2
1.321e-02	-4.33	non_small_cell_carcinoma	COSMIC cancer mutations	non_small_cell_carcinoma	5198	23	16828	49	PITPNC1,ATP13A4,BMPR1B,TNIK,LIFR,MSI2,PREX2,CTNND2,NFIB,NTRK2,SLC1A3,RORA,LSAMP,ADCY2,FBXL7,CLU,PTPRZ1,SOX5,QKI,ITPR2,NPAS3,FGFR3,PRKCA
1.321e-02	-4.33	lung-carcinoma-non_small_cell_carcinoma	COSMIC cancer mutations	lung-carcinoma-non_small_cell_carcinoma	5198	23	16828	49	PITPNC1,ATP13A4,BMPR1B,TNIK,LIFR,MSI2,PTPRZ1,SOX5,PREX2,CTNND2,QKI,NFIB,ITPR2,SLC1A3,NTRK2,NPAS3,RORA,LSAMP,FGFR3,ADCY2,FBXL7,PRKCA,CLU
1.325e-02	-4.32	positive regulation of synapse assembly	biological process	GO:0051965	65	2	18204	49	NRXN1,NTRK2
1.327e-02	-4.32	L-amino acid transmembrane transporter activity	molecular function	GO:0015179	66	2	18094	48	SLC1A3,SLC1A2
1.330e-02	-4.32	cellular response to stimulus	biological process	GO:0051716	6307	25	18204	49	ZBTB20,CPE,AQP4,MACF1,BMPR1B,PITPNC1,CTNND2,ATP1A2,SLC1A2,FGFR3,CLU,TNIK,DTNA,PREX2,SLC1A3,NRG3,ITPR2,EFEMP1,ADCY2,RORA,NTRK2,FMN2,LIFR,PRKCA,NFIA
1.332e-02	-4.32	human chr13q21.32	chromosome location	human chr13q21.32	7	1	26134	50	PCDH9
1.332e-02	-4.32	human chr8q13.2	chromosome location	human chr8q13.2	7	1	26134	50	PREX2
1.332e-02	-4.32	medulla	COSMIC cancer mutations	medulla	14778	48	16828	49	PTPRZ1,CPE,NHSL1,PON2,NRG3,ATP1A2,AQP4,GPM6A,FGFR3,DTNA,SFXN5,CTNND2,PREX2,ZBTB20,FMN2,PCDH9,CSGALNACT1,NTM,CLU,FBXL7,ADCY2,RBMS3,SOX5,MACF1,GLIS3,PRKCA,NFIA,ITPR2,NPAS3,QKI,MSI2,PARD3B,TNIK,LIFR,GLUD1,PITPNC1,BMPR1B,ATP13A4,CDH20,LSAMP,RORA,EFEMP1,SLC1A3,NRXN1,NTRK2,MGAT4C,SLC1A2,NFIB
1.334e-02	-4.32	D-Glutamine and D-glutamate metabolism	KEGG pathways	hsa00471	4	1	7161	24	GLUD1
1.334e-02	-4.32	D-Glutamine and D-glutamate metabolism	KEGG pathways	ko00471	4	1	7161	24	GLUD1
1.336e-02	-4.32	desmoplastic	COSMIC cancer mutations	desmoplastic	14779	48	16828	49	RBMS3,ADCY2,NTM,FBXL7,CLU,CSGALNACT1,PCDH9,FMN2,ZBTB20,SFXN5,PREX2,CTNND2,DTNA,AQP4,GPM6A,ATP1A2,FGFR3,PON2,NRG3,NHSL1,CPE,PTPRZ1,SLC1A2,NFIB,NTRK2,SLC1A3,NRXN1,MGAT4C,EFEMP1,RORA,LSAMP,CDH20,PITPNC1,ATP13A4,BMPR1B,GLUD1,TNIK,LIFR,PARD3B,MSI2,QKI,ITPR2,NFIA,NPAS3,MACF1,GLIS3,PRKCA,SOX5
1.336e-02	-4.32	organic acid transmembrane transporter activity	molecular function	GO:0005342	187	3	18094	48	SLC1A2,SLC1A3,SFXN5
1.339e-02	-4.31	large_intestine-caecum-carcinoma-adenocarcinoma	COSMIC cancer mutations	large_intestine-caecum-carcinoma-adenocarcinoma	14236	47	16828	49	PON2,NRG3,AQP4,GPM6A,ATP1A2,FGFR3,DTNA,PTPRZ1,CPE,NKAIN3,NHSL1,NTM,FBXL7,CLU,ADCY2,SFXN5,CTNND2,PREX2,FMN2,PCDH9,ZBTB20,CSGALNACT1,MACF1,GLIS3,PRKCA,NFIA,ITPR2,NPAS3,QKI,SOX5,CDH20,RORA,EFEMP1,LSAMP,SLC1A3,NRXN1,NTRK2,MGAT4C,SLC1A2,NFIB,TNIK,LIFR,PARD3B,GLUD1,PITPNC1,BMPR1B,ATP13A4
1.339e-02	-4.31	gephyrin clustering involved in postsynaptic density assembly	biological process	GO:0097116	5	1	18204	49	NRXN1
1.339e-02	-4.31	negative regulation of chondrocyte proliferation	biological process	GO:1902731	5	1	18204	49	BMPR1B
1.339e-02	-4.31	polar body extrusion after meiotic divisions	biological process	GO:0040038	5	1	18204	49	FMN2
1.339e-02	-4.31	tricarboxylic acid transport	biological process	GO:0006842	5	1	18204	49	SFXN5
1.339e-02	-4.31	ciliary neurotrophic factor-mediated signaling pathway	biological process	GO:0070120	5	1	18204	49	LIFR
1.339e-02	-4.31	synaptic signaling via neuropeptide	biological process	GO:0099538	5	1	18204	49	NTRK2
1.339e-02	-4.31	citrate transport	biological process	GO:0015746	5	1	18204	49	SFXN5
1.339e-02	-4.31	amygdala development	biological process	GO:0021764	5	1	18204	49	ATP1A2
1.339e-02	-4.31	tube lumen cavitation	biological process	GO:0060605	5	1	18204	49	NFIB
1.339e-02	-4.31	salivary gland cavitation	biological process	GO:0060662	5	1	18204	49	NFIB
1.339e-02	-4.31	central nervous system myelin maintenance	biological process	GO:0032286	5	1	18204	49	CLU
1.339e-02	-4.31	positive regulation of amyloid fibril formation	biological process	GO:1905908	5	1	18204	49	CLU
1.343e-02	-4.31	Protocadherin	interpro domains	IPR013585	5	1	18521	50	PCDH9
1.343e-02	-4.31	Aminotrans_3_PPA_site	interpro domains	IPR049704	5	1	18521	50	ETNPPL
1.343e-02	-4.31	BBP-like	interpro domains	IPR045071	5	1	18521	50	QKI
1.343e-02	-4.31	Mtc	interpro domains	IPR004686	5	1	18521	50	SFXN5
1.343e-02	-4.31	Aminotrans_3	interpro domains	IPR005814	5	1	18521	50	ETNPPL
1.343e-02	-4.31	PI_transfer	interpro domains	IPR001666	5	1	18521	50	PITPNC1
1.343e-02	-4.31	P-type_TPase_V	interpro domains	IPR006544	5	1	18521	50	ATP13A4
1.354e-02	-4.30	GRB2 (growth factor receptor bound protein 2)	protein interactions	2885	769	6	19454	50	FGFR3,MSI2,SLC1A2,NTRK2,CLU,PON2
1.364e-02	-4.29	neural nucleus development	biological process	GO:0048857	66	2	18204	49	GLUD1,NFIB
1.364e-02	-4.29	L-alpha-amino acid transmembrane transport	biological process	GO:1902475	66	2	18204	49	SLC1A2,SLC1A3
1.364e-02	-4.29	ERBB signaling pathway	biological process	GO:0038127	66	2	18204	49	NRG3,EFEMP1
1.368e-02	-4.29	IGc2	smart domains	SM00408	239	4	9717	38	LSAMP,NTM,FGFR3,NTRK2
1.369e-02	-4.29	Oxytocin signaling pathway	KEGG pathways	ko04921	152	3	7161	24	ADCY2,ITPR2,PRKCA
1.369e-02	-4.29	Oxytocin signaling pathway	KEGG pathways	hsa04921	152	3	7161	24	PRKCA,ITPR2,ADCY2
1.369e-02	-4.29	IP_trans	pfam domains	PF02121	5	1	17795	49	PITPNC1
1.369e-02	-4.29	Aminotran_3	pfam domains	PF00202	5	1	17795	49	ETNPPL
1.369e-02	-4.29	SFXNs	pfam domains	PF03820	5	1	17795	49	SFXN5
1.369e-02	-4.29	Protocadherin	pfam domains	PF08374	5	1	17795	49	PCDH9
1.379e-02	-4.28	RAC1 (Rac family small GTPase 1)	protein interactions	5879	1005	7	19454	50	PREX2,SLC1A3,DTNA,FMN2,PON2,PRKCA,MACF1
1.382e-02	-4.28	caecum	COSMIC cancer mutations	caecum	14248	47	16828	49	CDH20,LSAMP,RORA,EFEMP1,NTRK2,NRXN1,SLC1A3,MGAT4C,SLC1A2,NFIB,PARD3B,TNIK,LIFR,GLUD1,PITPNC1,BMPR1B,ATP13A4,MACF1,GLIS3,PRKCA,ITPR2,NFIA,NPAS3,QKI,SOX5,NTM,CLU,FBXL7,ADCY2,SFXN5,CTNND2,PREX2,ZBTB20,FMN2,PCDH9,CSGALNACT1,PON2,NRG3,ATP1A2,AQP4,GPM6A,FGFR3,DTNA,PTPRZ1,CPE,NKAIN3,NHSL1
1.383e-02	-4.28	ATP binding	molecular function	GO:0005524	1467	9	18094	48	GLUD1,PRKCA,ADCY2,TNIK,ATP13A4,BMPR1B,FGFR3,NTRK2,ATP1A2
1.396e-02	-4.27	Signaling by BRAF and RAF fusions	REACTOME pathways	R-HSA-6802952	60	2	10285	31	MACF1,QKI
1.399e-02	-4.27	PCDH20 (protocadherin 20)	protein interactions	64881	70	2	19454	50	MGAT4C,PON2
1.400e-02	-4.27	adenoma	COSMIC cancer mutations	adenoma	2873	15	16828	49	NTRK2,NPAS3,GPM6A,ADCY2,FGFR3,CDH20,MACF1,PRKCA,BMPR1B,ZBTB20,PCDH9,LIFR,PTPRZ1,CTNND2,SOX5
1.403e-02	-4.27	cell projection organization	biological process	GO:0030030	1200	8	18204	49	PTPRZ1,NFIB,TNIK,NRXN1,BMPR1B,GPM6A,CTNND2,PREX2
1.405e-02	-4.27	monoatomic ion transport	biological process	GO:0006811	964	7	18204	49	GPM6A,ATP1A2,SFXN5,SLC1A2,SLC1A3,ATP13A4,ITPR2
1.421e-02	-4.25	regulation of multicellular organismal process	biological process	GO:0051239	3113	15	18204	49	NRXN1,ZBTB20,EFEMP1,PTPRZ1,NFIB,MACF1,BMPR1B,SFXN5,ATP1A2,RORA,CLU,NTRK2,QKI,SOX5,PRKCA
1.422e-02	-4.25	Transmembrane transport of small molecules	REACTOME pathways	R-HSA-382551	677	6	10285	31	ATP1A2,AQP4,ADCY2,ATP13A4,SLC1A2,SLC1A3
1.429e-02	-4.25	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-acute_lymphoblastic_leukaemia	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-acute_lymphoblastic_leukaemia	2081	12	16828	49	NFIA,NTRK2,BMPR1B,DTNA,SOX5,PRKCA,PREX2,PTPRZ1,ADCY2,FGFR3,TNIK,ATP1A2
1.433e-02	-4.25	haematopoietic_and_lymphoid_tissue-spleen-lymphoid_neoplasm-marginal_zone_lymphoma	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue-spleen-lymphoid_neoplasm-marginal_zone_lymphoma	323	4	16828	49	NTM,PTPRZ1,ADCY2,PARD3B
1.433e-02	-4.25	NFIX (nuclear factor I X)	protein interactions	4784	198	3	19454	50	SOX5,NFIB,NFIA
1.433e-02	-4.25	CAMK2D (calcium/calmodulin dependent protein kinase II delta)	protein interactions	817	198	3	19454	50	ITPR2,FGFR3,PON2
1.435e-02	-4.24	small_intestine-carcinoid-endocrine_tumour	COSMIC cancer mutations	small_intestine-carcinoid-endocrine_tumour	175	3	16828	49	MACF1,CSGALNACT1,TNIK
1.437e-02	-4.24	ANK2 (ankyrin 2)	protein interactions	287	71	2	19454	50	TNIK,GPM6A
1.441e-02	-4.24	Ca2+ pathway	REACTOME pathways	R-HSA-4086398	61	2	10285	31	ITPR2,PRKCA
1.448e-02	-4.24	syringocystadenoma_papilliferum	COSMIC cancer mutations	syringocystadenoma_papilliferum	5	1	16828	49	FGFR3
1.448e-02	-4.24	skin-ear-other-nevus_sebaceous	COSMIC cancer mutations	skin-ear-other-nevus_sebaceous	5	1	16828	49	FGFR3
1.448e-02	-4.24	skin-flank-other-lichenoid_keratosis	COSMIC cancer mutations	skin-flank-other-lichenoid_keratosis	5	1	16828	49	FGFR3
1.448e-02	-4.24	skin-shoulder-other-nevus_sebaceous	COSMIC cancer mutations	skin-shoulder-other-nevus_sebaceous	5	1	16828	49	FGFR3
1.448e-02	-4.24	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-monoclonal_gammopathy_of_undetermined_significance	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-monoclonal_gammopathy_of_undetermined_significance	5	1	16828	49	FGFR3
1.448e-02	-4.24	skin-forearm-other-seborrhoeic_keratosis	COSMIC cancer mutations	skin-forearm-other-seborrhoeic_keratosis	5	1	16828	49	FGFR3
1.448e-02	-4.24	skin-lower_leg-malignant_melanoma-superficial_spreading	COSMIC cancer mutations	skin-lower_leg-malignant_melanoma-superficial_spreading	5	1	16828	49	PREX2
1.448e-02	-4.24	skin-upper_back-other-lichenoid_keratosis	COSMIC cancer mutations	skin-upper_back-other-lichenoid_keratosis	5	1	16828	49	FGFR3
1.448e-02	-4.24	skin-forearm-other-lichenoid_keratosis	COSMIC cancer mutations	skin-forearm-other-lichenoid_keratosis	5	1	16828	49	FGFR3
1.448e-02	-4.24	skin-lower_back-other-nevus_sebaceous	COSMIC cancer mutations	skin-lower_back-other-nevus_sebaceous	5	1	16828	49	FGFR3
1.448e-02	-4.24	skin-shoulder-other-lichenoid_keratosis	COSMIC cancer mutations	skin-shoulder-other-lichenoid_keratosis	5	1	16828	49	FGFR3
1.448e-02	-4.24	skin-arm-other-seborrhoeic_keratosis	COSMIC cancer mutations	skin-arm-other-seborrhoeic_keratosis	5	1	16828	49	FGFR3
1.448e-02	-4.24	skin-upper_leg-other-lichenoid_keratosis	COSMIC cancer mutations	skin-upper_leg-other-lichenoid_keratosis	5	1	16828	49	FGFR3
1.448e-02	-4.24	skin-chest-other-lichenoid_keratosis	COSMIC cancer mutations	skin-chest-other-lichenoid_keratosis	5	1	16828	49	FGFR3
1.448e-02	-4.24	skin-hip-other-seborrhoeic_keratosis	COSMIC cancer mutations	skin-hip-other-seborrhoeic_keratosis	5	1	16828	49	FGFR3
1.448e-02	-4.24	skin-neck-other-nevus_sebaceous	COSMIC cancer mutations	skin-neck-other-nevus_sebaceous	5	1	16828	49	FGFR3
1.448e-02	-4.24	skin-breast-other-lichenoid_keratosis	COSMIC cancer mutations	skin-breast-other-lichenoid_keratosis	5	1	16828	49	FGFR3
1.448e-02	-4.24	skin-lower_back-other-lichenoid_keratosis	COSMIC cancer mutations	skin-lower_back-other-lichenoid_keratosis	5	1	16828	49	FGFR3
1.448e-02	-4.24	skin-other-lichenoid_keratosis	COSMIC cancer mutations	skin-other-lichenoid_keratosis	5	1	16828	49	FGFR3
1.448e-02	-4.24	skin-upper_arm-other-lichenoid_keratosis	COSMIC cancer mutations	skin-upper_arm-other-lichenoid_keratosis	5	1	16828	49	FGFR3
1.448e-02	-4.24	skin-scalp-other-nevus_sebaceous	COSMIC cancer mutations	skin-scalp-other-nevus_sebaceous	5	1	16828	49	FGFR3
1.448e-02	-4.24	skin-adnexal_tumour-syringocystadenoma_papilliferum	COSMIC cancer mutations	skin-adnexal_tumour-syringocystadenoma_papilliferum	5	1	16828	49	FGFR3
1.448e-02	-4.24	skin-lower_leg-other-lichenoid_keratosis	COSMIC cancer mutations	skin-lower_leg-other-lichenoid_keratosis	5	1	16828	49	FGFR3
1.448e-02	-4.24	skin-face-other-lichenoid_keratosis	COSMIC cancer mutations	skin-face-other-lichenoid_keratosis	5	1	16828	49	FGFR3
1.448e-02	-4.24	skin-face-other-nevus_sebaceous	COSMIC cancer mutations	skin-face-other-nevus_sebaceous	5	1	16828	49	FGFR3
1.448e-02	-4.24	skin-hand-other-lichenoid_keratosis	COSMIC cancer mutations	skin-hand-other-lichenoid_keratosis	5	1	16828	49	FGFR3
1.448e-02	-4.24	lichenoid_keratosis	COSMIC cancer mutations	lichenoid_keratosis	5	1	16828	49	FGFR3
1.448e-02	-4.24	monoclonal_gammopathy_of_undetermined_significance	COSMIC cancer mutations	monoclonal_gammopathy_of_undetermined_significance	5	1	16828	49	FGFR3
1.448e-02	-4.24	skin-breast-other-nevus_sebaceous	COSMIC cancer mutations	skin-breast-other-nevus_sebaceous	5	1	16828	49	FGFR3
1.448e-02	-4.24	skin-neck-other-lichenoid_keratosis	COSMIC cancer mutations	skin-neck-other-lichenoid_keratosis	5	1	16828	49	FGFR3
1.451e-02	-4.23	NTRK3 (neurotrophic receptor tyrosine kinase 3)	protein interactions	4916	367	4	19454	50	GLUD1,TNIK,NTRK2,CLU
1.457e-02	-4.23	central_nervous_system-brain-primitive_neuroectodermal_tumour-medulloblastoma-large_cell	COSMIC cancer mutations	central_nervous_system-brain-primitive_neuroectodermal_tumour-medulloblastoma-large_cell	1117	8	16828	49	FMN2,ADCY2,CDH20,NRG3,SOX5,SLC1A2,ATP13A4,QKI
1.463e-02	-4.22	regulation of developmental process	biological process	GO:0050793	2540	13	18204	49	FGFR3,RORA,BMPR1B,QKI,SOX5,TNIK,PRKCA,NTRK2,NRXN1,NFIB,MACF1,PTPRZ1,EFEMP1
1.476e-02	-4.22	PPP3CC (protein phosphatase 3 catalytic subunit gamma)	protein interactions	5533	72	2	19454	50	BMPR1B,PARD3B
1.476e-02	-4.22	DPYSL3 (dihydropyrimidinase like 3)	protein interactions	1809	72	2	19454	50	GPM6A,TNIK
1.487e-02	-4.21	FOXA1 transcription factor network	Pathway Interaction DB	hnf3apathway	43	2	2226	10	NFIB,NFIA
1.493e-02	-4.20	presynapse	cellular component	GO:0098793	569	5	19108	49	NTRK2,NRXN1,SLC1A2,GPM6A,TNIK
1.493e-02	-4.20	meninges-meningioma	COSMIC cancer mutations	meninges-meningioma	327	4	16828	49	ITPR2,NFIA,FGFR3,FMN2
1.498e-02	-4.20	Disinhibition of SNARE formation	REACTOME pathways	R-HSA-114516	5	1	10285	31	PRKCA
1.498e-02	-4.20	NGF-independant TRKA activation	REACTOME pathways	R-HSA-187024	5	1	10285	31	NTRK2
1.501e-02	-4.20	lung-carcinoid-endocrine_tumour	COSMIC cancer mutations	lung-carcinoid-endocrine_tumour	502	5	16828	49	PRKCA,NTRK2,BMPR1B,FGFR3,TNIK
1.509e-02	-4.19	cell surface receptor signaling pathway	biological process	GO:0007166	1992	11	18204	49	FGFR3,CTNND2,BMPR1B,NFIA,TNIK,LIFR,NTRK2,CPE,MACF1,NRG3,EFEMP1
1.512e-02	-4.19	FEV (FEV transcription factor, ETS family member)	protein interactions	54738	202	3	19454	50	SOX5,NFIB,NFIA
1.520e-02	-4.19	Immunoglobulins	gene3d domains	2.60.40.10	721	6	14470	41	NTM,FGFR3,LSAMP,NTRK2,PTPRZ1,LIFR
1.520e-02	-4.19	skin-scalp-carcinoma-squamous_cell_carcinoma	COSMIC cancer mutations	skin-scalp-carcinoma-squamous_cell_carcinoma	1596	10	16828	49	PTPRZ1,MACF1,SOX5,ATP1A2,LSAMP,RORA,FGFR3,NRXN1,RBMS3,ATP13A4
1.532e-02	-4.18	Tiam2 (T cell lymphoma invasion and metastasis 2)	protein interactions	24001	6	1	19454	50	DTNA
1.532e-02	-4.18	SOX11 (SRY-box transcription factor 11)	protein interactions	6664	6	1	19454	50	SOX5
1.532e-02	-4.18	CYRIA (CYFIP related Rac1 interactor A)	protein interactions	81553	6	1	19454	50	GPM6A
1.532e-02	-4.18	Itch (itchy, E3 ubiquitin protein ligase)	protein interactions	16396	6	1	19454	50	GLIS3
1.532e-02	-4.18	ARMS2 (age-related maculopathy susceptibility 2)	protein interactions	387715	6	1	19454	50	PRKCA
1.532e-02	-4.18	SLC12A5 (solute carrier family 12 member 5)	protein interactions	57468	6	1	19454	50	GPM6A
1.532e-02	-4.18	Rhod (ras homolog family member D)	protein interactions	11854	6	1	19454	50	BMPR1B
1.532e-02	-4.18	Map2k3 (mitogen-activated protein kinase kinase 3)	protein interactions	26397	6	1	19454	50	BMPR1B
1.532e-02	-4.18	GDF6 (growth differentiation factor 6)	protein interactions	392255	6	1	19454	50	BMPR1B
1.532e-02	-4.18	DRP2 (dystrophin related protein 2)	protein interactions	1821	6	1	19454	50	DTNA
1.532e-02	-4.18	SYTL3 (synaptotagmin like 3)	protein interactions	94120	6	1	19454	50	NRXN1
1.532e-02	-4.18	Fancl (Fanconi anemia, complementation group L)	protein interactions	67030	6	1	19454	50	BMPR1B
1.532e-02	-4.18	FGF6 (fibroblast growth factor 6)	protein interactions	2251	6	1	19454	50	FGFR3
1.532e-02	-4.18	LIF (LIF interleukin 6 family cytokine)	protein interactions	3976	6	1	19454	50	LIFR
1.532e-02	-4.18	ADCY1 (adenylate cyclase 1)	protein interactions	107	6	1	19454	50	ADCY2
1.532e-02	-4.18	Klhl22 (kelch-like 22)	protein interactions	224023	6	1	19454	50	GLUD1
1.532e-02	-4.18	DAZ4 (deleted in azoospermia 4)	protein interactions	57135	6	1	19454	50	QKI
1.532e-02	-4.18	PBP2 (Pbp2p)	protein interactions	852533	6	1	19454	50	QKI
1.532e-02	-4.18	SOX1 (SRY-box transcription factor 1)	protein interactions	6656	6	1	19454	50	SOX5
1.532e-02	-4.18	FGF23 (fibroblast growth factor 23)	protein interactions	8074	6	1	19454	50	FGFR3
1.532e-02	-4.18	FGF18 (fibroblast growth factor 18)	protein interactions	8817	6	1	19454	50	FGFR3
1.532e-02	-4.18	Taok2 (TAO kinase 2)	protein interactions	381921	6	1	19454	50	CLU
1.532e-02	-4.18	Csnk1d (casein kinase 1, delta)	protein interactions	64462	6	1	19454	50	PRKCA
1.547e-02	-4.17	cell-cell contact zone	cellular component	GO:0044291	74	2	19108	49	PCDH9,ATP1A2
1.549e-02	-4.17	skin-ear-carcinoma-squamous_cell_carcinoma	COSMIC cancer mutations	skin-ear-carcinoma-squamous_cell_carcinoma	506	5	16828	49	FGFR3,LIFR,ZBTB20,MGAT4C,NPAS3
1.549e-02	-4.17	seminoma	COSMIC cancer mutations	seminoma	700	6	16828	49	TNIK,BMPR1B,FGFR3,NTRK2,PRKCA,PREX2
1.552e-02	-4.17	NFIC (nuclear factor I C)	protein interactions	4782	204	3	19454	50	NFIA,NFIB,SOX5
1.552e-02	-4.17	CASK (calcium/calmodulin dependent serine protein kinase)	protein interactions	8573	204	3	19454	50	NRXN1,DTNA,PARD3B
1.554e-02	-4.16	bone development	biological process	GO:0060348	195	3	18204	49	BMPR1B,CSGALNACT1,FGFR3
1.554e-02	-4.16	CACNA2D1 (calcium voltage-gated channel auxiliary subunit alpha2delta 1)	protein interactions	781	74	2	19454	50	GPM6A,PON2
1.555e-02	-4.16	marginal_zone_lymphoma	COSMIC cancer mutations	marginal_zone_lymphoma	331	4	16828	49	NTM,PTPRZ1,ADCY2,PARD3B
1.573e-02	-4.15	lung-carcinoid-endocrine_tumour-atypical	COSMIC cancer mutations	lung-carcinoid-endocrine_tumour-atypical	508	5	16828	49	FGFR3,BMPR1B,TNIK,PRKCA,NTRK2
1.581e-02	-4.15	ciliary neurotrophic factor receptor binding	molecular function	GO:0005127	6	1	18094	48	LIFR
1.581e-02	-4.15	glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity	molecular function	GO:0047238	6	1	18094	48	CSGALNACT1
1.581e-02	-4.15	steroid hormone binding	molecular function	GO:1990239	6	1	18094	48	ATP1A2
1.581e-02	-4.15	arylesterase activity	molecular function	GO:0004064	6	1	18094	48	PON2
1.604e-02	-4.13	intracellular water homeostasis	biological process	GO:0009992	6	1	18204	49	AQP4
1.604e-02	-4.13	mammary gland formation	biological process	GO:0060592	6	1	18204	49	NRG3
1.604e-02	-4.13	positive regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway	biological process	GO:0106071	6	1	18204	49	PRKCA
1.604e-02	-4.13	gamma-aminobutyric acid biosynthetic process	biological process	GO:0009449	6	1	18204	49	SLC1A3
1.604e-02	-4.13	fused antrum stage	biological process	GO:0048165	6	1	18204	49	BMPR1B
1.604e-02	-4.13	protein targeting to vacuole involved in autophagy	biological process	GO:0071211	6	1	18204	49	CLU
1.604e-02	-4.13	establishment of meiotic spindle localization	biological process	GO:0051295	6	1	18204	49	FMN2
1.604e-02	-4.13	imitative learning	biological process	GO:0098596	6	1	18204	49	NRXN1
1.604e-02	-4.13	type II pneumocyte differentiation	biological process	GO:0060510	6	1	18204	49	NFIB
1.604e-02	-4.13	postsynaptic density protein 95 clustering	biological process	GO:0097119	6	1	18204	49	NRXN1
1.604e-02	-4.13	asymmetric neuroblast division	biological process	GO:0055059	6	1	18204	49	SOX5
1.604e-02	-4.13	ERBB4-ERBB4 signaling pathway	biological process	GO:0038138	6	1	18204	49	NRG3
1.604e-02	-4.13	vocal learning	biological process	GO:0042297	6	1	18204	49	NRXN1
1.609e-02	-4.13	RIH_assoc-dom	interpro domains	IPR013662	6	1	18521	50	ITPR2
1.609e-02	-4.13	EF-hand_dom_typ2	interpro domains	IPR015154	6	1	18521	50	DTNA
1.609e-02	-4.13	GAR_dom	interpro domains	IPR003108	6	1	18521	50	MACF1
1.609e-02	-4.13	GAR_dom_sf	interpro domains	IPR036534	6	1	18521	50	MACF1
1.609e-02	-4.13	RyR/IP3R_RIH_dom_sf	interpro domains	IPR035910	6	1	18521	50	ITPR2
1.609e-02	-4.13	Ins145_P3_rcpt	interpro domains	IPR014821	6	1	18521	50	ITPR2
1.609e-02	-4.13	Syndecan/Neurexin_dom	interpro domains	IPR027789	6	1	18521	50	NRXN1
1.609e-02	-4.13	RIH_dom	interpro domains	IPR000699	6	1	18521	50	ITPR2
1.609e-02	-4.13	EF-hand_dom_typ1	interpro domains	IPR015153	6	1	18521	50	DTNA
1.609e-02	-4.13	Adcy_conserved_dom	interpro domains	IPR009398	6	1	18521	50	ADCY2
1.609e-02	-4.13	GLI-like	interpro domains	IPR043359	6	1	18521	50	GLIS3
1.609e-02	-4.13	P-type_ATPase_IIC	interpro domains	IPR005775	6	1	18521	50	ATP1A2
1.609e-02	-4.13	Desmoplakin_SH3	interpro domains	IPR041615	6	1	18521	50	MACF1
1.609e-02	-4.13	Ryanodine_IP3_receptor	interpro domains	IPR015925	6	1	18521	50	ITPR2
1.609e-02	-4.13	large_cell	COSMIC cancer mutations	large_cell	14845	48	16828	49	SOX5,PRKCA,GLIS3,MACF1,QKI,NPAS3,ITPR2,NFIA,PARD3B,MSI2,LIFR,TNIK,ATP13A4,BMPR1B,PITPNC1,GLUD1,LSAMP,RORA,EFEMP1,CDH20,NFIB,SLC1A2,MGAT4C,NRXN1,NTRK2,SLC1A3,CPE,PTPRZ1,NHSL1,FGFR3,ATP1A2,AQP4,GPM6A,NRG3,PON2,DTNA,ZBTB20,PCDH9,FMN2,CTNND2,PREX2,SFXN5,CSGALNACT1,ADCY2,CLU,FBXL7,NTM,RBMS3
1.618e-02	-4.12	skin-trunk-malignant_melanoma	COSMIC cancer mutations	skin-trunk-malignant_melanoma	2647	14	16828	49	ATP1A2,LSAMP,CDH20,NRG3,NRXN1,SLC1A3,MGAT4C,LIFR,PCDH9,PTPRZ1,SOX5,CTNND2,PREX2,ATP13A4
1.625e-02	-4.12	Constitutive Signaling by Aberrant PI3K in Cancer	REACTOME pathways	R-HSA-2219530	65	2	10285	31	NRG3,FGFR3
1.629e-02	-4.12	regulation of multicellular organismal development	biological process	GO:2000026	1484	9	18204	49	EFEMP1,PTPRZ1,NTRK2,MACF1,PRKCA,SOX5,QKI,BMPR1B,NRXN1
1.635e-02	-4.11	MIR200A (microRNA 200a)	protein interactions	406983	76	2	19454	50	MSI2,QKI
1.640e-02	-4.11	positive regulation of ERK1 and ERK2 cascade	biological process	GO:0070374	199	3	18204	49	NTRK2,PRKCA,FGFR3
1.641e-02	-4.11	RIH_assoc	pfam domains	PF08454	6	1	17795	49	ITPR2
1.641e-02	-4.11	EF-hand_3	pfam domains	PF09069	6	1	17795	49	DTNA
1.641e-02	-4.11	RYDR_ITPR	pfam domains	PF01365	6	1	17795	49	ITPR2
1.641e-02	-4.11	GAS2	pfam domains	PF02187	6	1	17795	49	MACF1
1.641e-02	-4.11	EF-hand_2	pfam domains	PF09068	6	1	17795	49	DTNA
1.641e-02	-4.11	Syndecan	pfam domains	PF01034	6	1	17795	49	NRXN1
1.641e-02	-4.11	Ins145_P3_rec	pfam domains	PF08709	6	1	17795	49	ITPR2
1.641e-02	-4.11	Plectin	pfam domains	PF00681	6	1	17795	49	MACF1
1.641e-02	-4.11	SH3_10	pfam domains	PF17902	6	1	17795	49	MACF1
1.641e-02	-4.11	Adcy_cons_dom	pfam domains	PF06327	6	1	17795	49	ADCY2
1.650e-02	-4.10	cGMP-PKG signaling pathway	KEGG pathways	ko04022	163	3	7161	24	ITPR2,ADCY2,ATP1A2
1.650e-02	-4.10	cGMP-PKG signaling pathway	KEGG pathways	hsa04022	163	3	7161	24	ADCY2,ITPR2,ATP1A2
1.652e-02	-4.10	peptide metabolic process	biological process	GO:0006518	73	2	18204	49	CPE,SLC1A2
1.652e-02	-4.10	vasculogenesis	biological process	GO:0001570	73	2	18204	49	QKI,NTRK2
1.652e-02	-4.10	neuron fate commitment	biological process	GO:0048663	73	2	18204	49	NFIA,NFIB
1.653e-02	-4.10	VEGFA-VEGFR2 Pathway	REACTOME pathways	R-HSA-4420097	330	4	10285	31	ITPR2,FGFR3,NRG3,PRKCA
1.660e-02	-4.10	atypical	COSMIC cancer mutations	atypical	515	5	16828	49	NTRK2,PRKCA,TNIK,FGFR3,BMPR1B
1.673e-02	-4.09	axonogenesis	biological process	GO:0007409	366	4	18204	49	NFIB,PTPRZ1,BMPR1B,NRXN1
1.675e-02	-4.09	skin-head_neck-malignant_melanoma-superficial_spreading	COSMIC cancer mutations	skin-head_neck-malignant_melanoma-superficial_spreading	923	7	16828	49	CTNND2,PREX2,MACF1,ADCY2,LIFR,MGAT4C,ATP13A4
1.675e-02	-4.09	TLE1 (TLE family member 1, transcriptional corepressor)	protein interactions	7088	210	3	19454	50	SOX5,NFIB,NFIA
1.680e-02	-4.09	soft_tissue-striated_muscle-rhabdomyosarcoma-embryonal	COSMIC cancer mutations	soft_tissue-striated_muscle-rhabdomyosarcoma-embryonal	2659	14	16828	49	MACF1,GLIS3,PON2,AQP4,RORA,ADCY2,FGFR3,NFIA,NPAS3,PTPRZ1,CTNND2,PREX2,FMN2,PARD3B
1.680e-02	-4.09	embryonal	COSMIC cancer mutations	embryonal	2659	14	16828	49	PARD3B,FMN2,PTPRZ1,PREX2,CTNND2,NFIA,NPAS3,RORA,AQP4,FGFR3,ADCY2,PON2,MACF1,GLIS3
1.688e-02	-4.08	Leucine Dehydrogenase, chain A, domain 1	gene3d domains	3.40.50.10860	6	1	14470	41	GLUD1
1.688e-02	-4.08	IP3 receptor type 1 binding core, RIH domain	gene3d domains	1.25.10.30	6	1	14470	41	ITPR2
1.688e-02	-4.08	Plakin repeat	gene3d domains	3.90.1290.10	6	1	14470	41	MACF1
1.688e-02	-4.08	Gas2-like domain	gene3d domains	3.30.920.20	6	1	14470	41	MACF1
1.693e-02	-4.08	Long-term depression	KEGG pathways	ko04730	60	2	7161	24	PRKCA,ITPR2
1.693e-02	-4.08	Long-term depression	KEGG pathways	hsa04730	60	2	7161	24	ITPR2,PRKCA
1.695e-02	-4.08	positive regulation of gliogenesis	biological process	GO:0014015	74	2	18204	49	QKI,PTPRZ1
1.701e-02	-4.07	middle_lobe	COSMIC cancer mutations	middle_lobe	1382	9	16828	49	ITPR2,ATP13A4,MACF1,CTNND2,PCDH9,ATP1A2,PARD3B,FGFR3,CPE
1.705e-02	-4.07	HAD_sf	interpro domains	IPR023214	74	2	18521	50	ATP1A2,ATP13A4
1.709e-02	-4.07	human chr4q22.3	chromosome location	human chr4q22.3	9	1	26134	50	BMPR1B
1.712e-02	-4.07	AA_TRANSFER_CLASS_3	prosite domains	PS00600	5	1	12186	42	ETNPPL
1.715e-02	-4.07	extremity	COSMIC cancer mutations	extremity	1876	11	16828	49	PITPNC1,ATP13A4,NTRK2,FMN2,PCDH9,ADCY2,FGFR3,PTPRZ1,CDH20,PREX2,FBXL7
1.717e-02	-4.06	Nedd4 (NEDD4 E3 ubiquitin protein ligase)	protein interactions	25489	78	2	19454	50	BMPR1B,NTRK2
1.717e-02	-4.06	PRR12 (proline rich 12)	protein interactions	57479	78	2	19454	50	NFIB,NFIA
1.717e-02	-4.06	ATP2B3 (ATPase plasma membrane Ca2+ transporting 3)	protein interactions	492	78	2	19454	50	GPM6A,CSGALNACT1
1.717e-02	-4.06	MIR34C (microRNA 34c)	protein interactions	407042	78	2	19454	50	QKI,MSI2
1.717e-02	-4.06	SDC4 (syndecan 4)	protein interactions	6385	78	2	19454	50	PRKCA,FGFR3
1.717e-02	-4.06	ANKRD40 (ankyrin repeat domain 40)	protein interactions	91369	78	2	19454	50	MSI2,SOX5
1.718e-02	-4.06	DNAJC2 (DnaJ heat shock protein family (Hsp40) member C2)	protein interactions	27000	212	3	19454	50	GLUD1,TNIK,MACF1
1.735e-02	-4.05	kidney-carcinoma-collecting_duct_carcinoma	COSMIC cancer mutations	kidney-carcinoma-collecting_duct_carcinoma	6	1	16828	49	FGFR3
1.735e-02	-4.05	skin-forearm-malignant_melanoma-superficial_spreading	COSMIC cancer mutations	skin-forearm-malignant_melanoma-superficial_spreading	6	1	16828	49	PREX2
1.735e-02	-4.05	skin-in_situ_epithelial_neoplasm-actinic_keratosis	COSMIC cancer mutations	skin-in_situ_epithelial_neoplasm-actinic_keratosis	6	1	16828	49	FGFR3
1.735e-02	-4.05	collecting_duct_carcinoma	COSMIC cancer mutations	collecting_duct_carcinoma	6	1	16828	49	FGFR3
1.735e-02	-4.05	skin-face-other-seborrhoeic_keratosis	COSMIC cancer mutations	skin-face-other-seborrhoeic_keratosis	6	1	16828	49	FGFR3
1.735e-02	-4.05	skin-upper_leg-other-seborrhoeic_keratosis	COSMIC cancer mutations	skin-upper_leg-other-seborrhoeic_keratosis	6	1	16828	49	FGFR3
1.735e-02	-4.05	skin-arm-epidermal_nevus	COSMIC cancer mutations	skin-arm-epidermal_nevus	6	1	16828	49	FGFR3
1.735e-02	-4.05	skin-head_neck-epidermal_nevus	COSMIC cancer mutations	skin-head_neck-epidermal_nevus	6	1	16828	49	FGFR3
1.735e-02	-4.05	skin-trunk-epidermal_nevus	COSMIC cancer mutations	skin-trunk-epidermal_nevus	6	1	16828	49	FGFR3
1.735e-02	-4.05	skin-epidermal_nevus	COSMIC cancer mutations	skin-epidermal_nevus	6	1	16828	49	FGFR3
1.735e-02	-4.05	skin-head_neck-malignant_melanoma	COSMIC cancer mutations	skin-head_neck-malignant_melanoma	6	1	16828	49	PREX2
1.735e-02	-4.05	skin-flank-other-seborrhoeic_keratosis	COSMIC cancer mutations	skin-flank-other-seborrhoeic_keratosis	6	1	16828	49	FGFR3
1.735e-02	-4.05	skin-benign_melanocytic_nevus-lentiginous_nevus	COSMIC cancer mutations	skin-benign_melanocytic_nevus-lentiginous_nevus	6	1	16828	49	FGFR3
1.735e-02	-4.05	skin-adnexal_tumour-trichoblastoma	COSMIC cancer mutations	skin-adnexal_tumour-trichoblastoma	6	1	16828	49	FGFR3
1.735e-02	-4.05	lentiginous_nevus	COSMIC cancer mutations	lentiginous_nevus	6	1	16828	49	FGFR3
1.735e-02	-4.05	skin-abdomen-other-seborrhoeic_keratosis	COSMIC cancer mutations	skin-abdomen-other-seborrhoeic_keratosis	6	1	16828	49	FGFR3
1.735e-02	-4.05	skin-in_situ_epithelial_neoplasm-Bowen_disease	COSMIC cancer mutations	skin-in_situ_epithelial_neoplasm-Bowen_disease	6	1	16828	49	FGFR3
1.735e-02	-4.05	skin-lower_leg-epidermal_nevus	COSMIC cancer mutations	skin-lower_leg-epidermal_nevus	6	1	16828	49	FGFR3
1.735e-02	-4.05	autonomic_ganglia-paraganglioma-benign	COSMIC cancer mutations	autonomic_ganglia-paraganglioma-benign	6	1	16828	49	NHSL1
1.735e-02	-4.05	skin-lower_back-other-seborrhoeic_keratosis	COSMIC cancer mutations	skin-lower_back-other-seborrhoeic_keratosis	6	1	16828	49	FGFR3
1.735e-02	-4.05	skin-back-other-seborrhoeic_keratosis	COSMIC cancer mutations	skin-back-other-seborrhoeic_keratosis	6	1	16828	49	FGFR3
1.738e-02	-4.05	amino acid biosynthetic process	biological process	GO:0008652	75	2	18204	49	SLC1A3,GLUD1
1.744e-02	-4.05	Activation of PKC Through G Protein-Coupled Receptor	SMPDB pathways	SMP0000749	4	1	1369	6	PRKCA
1.761e-02	-4.04	NCK1 (NCK adaptor protein 1)	protein interactions	4690	214	3	19454	50	NTRK2,NHSL1,TNIK
1.766e-02	-4.04	stomach-adenocarcinoma	COSMIC cancer mutations	stomach-adenocarcinoma	4101	19	16828	49	PARD3B,PCDH9,FMN2,CTNND2,PREX2,ATP13A4,CSGALNACT1,FGFR3,ATP1A2,RORA,PRKCA,NRG3,PON2,CDH20,MACF1,QKI,SLC1A2,MGAT4C,ITPR2
1.767e-02	-4.04	mannosyl-glycoprotein N-acetylglucosaminyltransferases	BIOCYC pathways	META_PWY-7426	8	1	902	2	MGAT4C
1.767e-02	-4.04	adenyl ribonucleotide binding	molecular function	GO:0032559	1528	9	18094	48	PRKCA,GLUD1,ATP1A2,NTRK2,BMPR1B,FGFR3,ATP13A4,TNIK,ADCY2
1.771e-02	-4.03	intracellular signal transduction	biological process	GO:0035556	1505	9	18204	49	FGFR3,ATP1A2,PREX2,ITPR2,NRG3,FMN2,ADCY2,TNIK,PRKCA
1.782e-02	-4.03	cerebellar mossy fiber	cellular component	GO:0044300	7	1	19108	49	NFIB
1.785e-02	-4.03	nitrogen compound transport	biological process	GO:0071705	1507	9	18204	49	CLU,FMN2,NTRK2,QKI,ATP13A4,MACF1,SLC1A3,CPE,SLC1A2
1.786e-02	-4.03	C7 (complement C7)	protein interactions	730	7	1	19454	50	CLU
1.786e-02	-4.03	RGMB (repulsive guidance molecule BMP co-receptor b)	protein interactions	285704	7	1	19454	50	BMPR1B
1.786e-02	-4.03	Pum2 (pumilio RNA-binding family member 2)	protein interactions	80913	7	1	19454	50	QKI
1.786e-02	-4.03	SOAT2 (sterol O-acyltransferase 2)	protein interactions	8435	7	1	19454	50	CLU
1.786e-02	-4.03	Smad7 (SMAD family member 7)	protein interactions	17131	7	1	19454	50	BMPR1B
1.786e-02	-4.03	ABCC12 (ATP binding cassette subfamily C member 12)	protein interactions	94160	7	1	19454	50	NPAS3
1.786e-02	-4.03	Uhmk1 (U2AF homology motif (UHM) kinase 1)	protein interactions	16589	7	1	19454	50	BMPR1B
1.786e-02	-4.03	SLC16A5 (solute carrier family 16 member 5)	protein interactions	9121	7	1	19454	50	PTPRZ1
1.786e-02	-4.03	Smurf1 (SMAD specific E3 ubiquitin protein ligase 1)	protein interactions	75788	7	1	19454	50	GLIS3
1.786e-02	-4.03	ZBTB45 (zinc finger and BTB domain containing 45)	protein interactions	84878	7	1	19454	50	ZBTB20
1.786e-02	-4.03	FGF5 (fibroblast growth factor 5)	protein interactions	2250	7	1	19454	50	FGFR3
1.786e-02	-4.03	C8B (complement C8 beta chain)	protein interactions	732	7	1	19454	50	CLU
1.786e-02	-4.03	SASH3 (SAM and SH3 domain containing 3)	protein interactions	54440	7	1	19454	50	BMPR1B
1.786e-02	-4.03	CYP4F8 (cytochrome P450 family 4 subfamily F member 8)	protein interactions	11283	7	1	19454	50	CLU
1.786e-02	-4.03	Fbxo3 (F-box protein 3)	protein interactions	57443	7	1	19454	50	BMPR1B
1.790e-02	-4.02	Signaling by VEGF	REACTOME pathways	R-HSA-194138	338	4	10285	31	PRKCA,ITPR2,FGFR3,NRG3
1.795e-02	-4.02	Activation of TRKA receptors	REACTOME pathways	R-HSA-187015	6	1	10285	31	NTRK2
1.801e-02	-4.02	GJB1 (gap junction protein beta 1)	protein interactions	2705	80	2	19454	50	PRKCA,MSI2
1.801e-02	-4.02	BCL9 (BCL9 transcription coactivator)	protein interactions	607	80	2	19454	50	NFIB,NFIA
1.804e-02	-4.01	ATP2B1 (ATPase plasma membrane Ca2+ transporting 1)	protein interactions	490	216	3	19454	50	NTRK2,PRKCA,FGFR3
1.826e-02	-4.00	GFAP (glial fibrillary acidic protein)	protein interactions	2670	217	3	19454	50	NKAIN3,RORA,PRKCA
1.827e-02	-4.00	positive regulation of axonogenesis	biological process	GO:0050772	77	2	18204	49	MACF1,NTRK2
1.827e-02	-4.00	neural retina development	biological process	GO:0003407	77	2	18204	49	GPM6A,NTRK2
1.827e-02	-4.00	regulation of synaptic transmission, glutamatergic	biological process	GO:0051966	77	2	18204	49	NRXN1,ATP1A2
1.827e-02	-4.00	BMP signaling pathway	biological process	GO:0030509	77	2	18204	49	BMPR1B,NFIA
1.843e-02	-3.99	phosphatidic acid transfer activity	molecular function	GO:1990050	7	1	18094	48	PITPNC1
1.843e-02	-3.99	L-leucine binding	molecular function	GO:0070728	7	1	18094	48	GLUD1
1.843e-02	-3.99	P-type sodium transporter activity	molecular function	GO:0008554	7	1	18094	48	ATP1A2
1.843e-02	-3.99	P-type sodium:potassium-exchanging transporter activity	molecular function	GO:0005391	7	1	18094	48	ATP1A2
1.843e-02	-3.99	SOX17 (SRY-box transcription factor 17)	protein interactions	64321	81	2	19454	50	NFIB,NFIA
1.844e-02	-3.99	regulation of neurogenesis	biological process	GO:0050767	377	4	18204	49	MACF1,QKI,PTPRZ1,NTRK2
1.855e-02	-3.99	oesophagus-lower_third-carcinoma-adenocarcinoma	COSMIC cancer mutations	oesophagus-lower_third-carcinoma-adenocarcinoma	6302	26	16828	49	MGAT4C,NTRK2,NRXN1,CDH20,ADCY2,EFEMP1,RORA,GLUD1,ATP13A4,PREX2,CTNND2,ZBTB20,PARD3B,PCDH9,FMN2,NPAS3,ITPR2,QKI,PRKCA,NRG3,PON2,MACF1,AQP4,SOX5,PTPRZ1,CPE
1.860e-02	-3.98	HAD superfamily/HAD-like	gene3d domains	3.40.50.1000	74	2	14470	41	ATP13A4,ATP1A2
1.867e-02	-3.98	transmembrane transport	biological process	GO:0055085	1264	8	18204	49	SLC1A3,SFXN5,SLC1A2,GPM6A,ATP1A2,ITPR2,ATP13A4,AQP4
1.869e-02	-3.98	observational learning	biological process	GO:0098597	7	1	18204	49	NRXN1
1.869e-02	-3.98	interneuron migration from the subpallium to the cortex	biological process	GO:0021830	7	1	18204	49	NRG3
1.869e-02	-3.98	anterior commissure morphogenesis	biological process	GO:0021960	7	1	18204	49	NFIB
1.869e-02	-3.98	parallel actin filament bundle assembly	biological process	GO:0030046	7	1	18204	49	FMN2
1.869e-02	-3.98	chaperone-mediated autophagy	biological process	GO:0061684	7	1	18204	49	CLU
1.869e-02	-3.98	chromosome movement towards spindle pole	biological process	GO:0051305	7	1	18204	49	FMN2
1.869e-02	-3.98	negative regulation of mesenchymal cell proliferation	biological process	GO:0072201	7	1	18204	49	NFIB
1.869e-02	-3.98	regulation of oligodendrocyte progenitor proliferation	biological process	GO:0070445	7	1	18204	49	PTPRZ1
1.869e-02	-3.98	regulation of epithelial cell proliferation involved in lung morphogenesis	biological process	GO:2000794	7	1	18204	49	NFIB
1.869e-02	-3.98	post-embryonic eye morphogenesis	biological process	GO:0048050	7	1	18204	49	EFEMP1
1.869e-02	-3.98	regulation of 3'-UTR-mediated mRNA stabilization	biological process	GO:1905868	7	1	18204	49	QKI
1.875e-02	-3.98	Plectin_repeat	interpro domains	IPR001101	7	1	18521	50	MACF1
1.875e-02	-3.98	Hud_Sxl_RNA	interpro domains	IPR002343	7	1	18521	50	RBMS3
1.875e-02	-3.98	GS_dom	interpro domains	IPR003605	7	1	18521	50	BMPR1B
1.875e-02	-3.98	Plakophilin/d_Catenin	interpro domains	IPR028435	7	1	18521	50	CTNND2
1.875e-02	-3.98	Hematopoietin_rcpt_Gp130_CS	interpro domains	IPR003529	7	1	18521	50	LIFR
1.875e-02	-3.98	Plakin_repeat_sf	interpro domains	IPR035915	7	1	18521	50	MACF1
1.875e-02	-3.98	Aquaporin_transptr	interpro domains	IPR034294	7	1	18521	50	AQP4
1.881e-02	-3.97	thyroid-carcinoma	COSMIC cancer mutations	thyroid-carcinoma	4126	19	16828	49	PTPRZ1,SOX5,CTNND2,TNIK,LIFR,PCDH9,CPE,ATP13A4,MACF1,GLIS3,AQP4,LSAMP,ATP1A2,FGFR3,ADCY2,NFIA,ITPR2,NRXN1,DTNA
1.881e-02	-3.97	HAX1 (HCLS1 associated protein X-1)	protein interactions	10456	397	4	19454	50	NTM,CLU,GPM6A,ITPR2
1.882e-02	-3.97	HAD-like_sf	interpro domains	IPR036412	78	2	18521	50	ATP1A2,ATP13A4
1.886e-02	-3.97	GSC (goosecoid homeobox)	protein interactions	145258	82	2	19454	50	SOX5,NFIA
1.886e-02	-3.97	NR2C1 (nuclear receptor subfamily 2 group C member 1)	protein interactions	7181	82	2	19454	50	NFIB,NFIA
1.897e-02	-3.96	human chr9p24.2	chromosome location	human chr9p24.2	10	1	26134	50	GLIS3
1.897e-02	-3.96	human chr12p11.23	chromosome location	human chr12p11.23	10	1	26134	50	ITPR2
1.909e-02	-3.96	solute:sodium symporter activity	molecular function	GO:0015370	80	2	18094	48	SLC1A2,SLC1A3
1.912e-02	-3.96	TGF_beta_GS	pfam domains	PF08515	7	1	17795	49	BMPR1B
1.914e-02	-3.96	central_nervous_system-brain-glioma-oligodendroglioma_Grade_II	COSMIC cancer mutations	central_nervous_system-brain-glioma-oligodendroglioma_Grade_II	73	2	16828	49	FGFR3,MACF1
1.917e-02	-3.95	regulation of glial cell differentiation	biological process	GO:0045685	79	2	18204	49	QKI,PTPRZ1
1.917e-02	-3.95	Synaptic Vesicle Pathway	WikiPathways	WP2267	52	2	5310	22	SLC1A3,ATP1A2
1.925e-02	-3.95	RHOB (ras homolog family member B)	protein interactions	388	832	6	19454	50	SLC1A3,PARD3B,FMN2,DTNA,TNIK,MACF1
1.930e-02	-3.95	SYT1 (synaptotagmin 1)	protein interactions	6857	83	2	19454	50	NRXN1,GPM6A
1.930e-02	-3.95	DNM3 (dynamin 3)	protein interactions	26052	83	2	19454	50	FGFR3,GPM6A
1.930e-02	-3.95	PAX2 (paired box 2)	protein interactions	5076	83	2	19454	50	NFIB,NFIA
1.930e-02	-3.95	TM2D3 (TM2 domain containing 3)	protein interactions	80213	83	2	19454	50	FGFR3,PON2
1.944e-02	-3.94	inorganic cation transmembrane transporter activity	molecular function	GO:0022890	589	5	18094	48	ATP1A2,ITPR2,SLC1A2,GPM6A,SLC1A3
1.952e-02	-3.94	regulation of signaling	biological process	GO:0023051	3534	16	18204	49	BMPR1B,RORA,ATP1A2,CTNND2,FGFR3,NTRK2,CLU,PRKCA,TNIK,GLUD1,NRXN1,SLC1A3,PREX2,RBMS3,NRG3,MACF1
1.955e-02	-3.93	intracellular chemical homeostasis	biological process	GO:0055082	581	5	18204	49	ATP13A4,SLC1A3,ATP1A2,AQP4,ZBTB20
1.962e-02	-3.93	skin-nipple-malignant_melanoma	COSMIC cancer mutations	skin-nipple-malignant_melanoma	197	3	16828	49	FMN2,EFEMP1,BMPR1B
1.962e-02	-3.93	nipple	COSMIC cancer mutations	nipple	197	3	16828	49	BMPR1B,EFEMP1,FMN2
1.964e-02	-3.93	oligodendroglioma_Grade_II	COSMIC cancer mutations	oligodendroglioma_Grade_II	74	2	16828	49	FGFR3,MACF1
1.974e-02	-3.93	Tyr_kinase_cat_dom	interpro domains	IPR020635	80	2	18521	50	NTRK2,FGFR3
1.976e-02	-3.92	FBXO2 (F-box protein 2)	protein interactions	26232	403	4	19454	50	FGFR3,PCDH9,NTM,LIFR
1.987e-02	-3.92	regulation of cell communication	biological process	GO:0010646	3541	16	18204	49	RORA,FGFR3,ATP1A2,CTNND2,BMPR1B,TNIK,PRKCA,NTRK2,CLU,PREX2,SLC1A3,NRXN1,GLUD1,MACF1,RBMS3,NRG3
1.991e-02	-3.92	FGFR1 (fibroblast growth factor receptor 1)	protein interactions	2260	611	5	19454	50	NHSL1,TNIK,CLU,FGFR3,DTNA
1.993e-02	-3.92	PITRANSFER	prints domains	PR00391	5	1	5227	21	PITPNC1
1.995e-02	-3.91	Glycosaminoglycan biosynthesis, chondroitin sulfate backbone	KEGG pathways	hsa_M00058	6	1	7161	24	CSGALNACT1
1.995e-02	-3.91	Glycosaminoglycan biosynthesis, chondroitin sulfate backbone	KEGG pathways	M00058	6	1	7161	24	CSGALNACT1
2.008e-02	-3.91	FOXC1 (forkhead box C1)	protein interactions	2296	225	3	19454	50	SOX5,NFIB,NFIA
2.009e-02	-3.91	adult locomotory behavior	biological process	GO:0008344	81	2	18204	49	PREX2,ATP1A2
2.009e-02	-3.91	regulation of amide metabolic process	biological process	GO:0034248	81	2	18204	49	CLU,NTRK2
2.018e-02	-3.90	SSBP3 (single stranded DNA binding protein 3)	protein interactions	23648	85	2	19454	50	NFIB,NFIA
2.018e-02	-3.90	CCND3 (cyclin D3)	protein interactions	896	85	2	19454	50	QKI,CLU
2.021e-02	-3.90	trichilemmoma	COSMIC cancer mutations	trichilemmoma	7	1	16828	49	FGFR3
2.021e-02	-3.90	skin-face-adnexal_tumour-malignant_adnexal_tumour	COSMIC cancer mutations	skin-face-adnexal_tumour-malignant_adnexal_tumour	7	1	16828	49	FGFR3
2.021e-02	-3.90	skin-chest-other-seborrhoeic_keratosis	COSMIC cancer mutations	skin-chest-other-seborrhoeic_keratosis	7	1	16828	49	FGFR3
2.021e-02	-3.90	skin-adnexal_tumour-trichilemmoma	COSMIC cancer mutations	skin-adnexal_tumour-trichilemmoma	7	1	16828	49	FGFR3
2.021e-02	-3.90	skin-other-nevus_sebaceous	COSMIC cancer mutations	skin-other-nevus_sebaceous	7	1	16828	49	FGFR3
2.021e-02	-3.90	skin-benign_melanocytic_nevus-intradermal	COSMIC cancer mutations	skin-benign_melanocytic_nevus-intradermal	7	1	16828	49	FGFR3
2.021e-02	-3.90	skin-shoulder-other-seborrhoeic_keratosis	COSMIC cancer mutations	skin-shoulder-other-seborrhoeic_keratosis	7	1	16828	49	FGFR3
2.021e-02	-3.90	skin-face-malignant_melanoma-nodular	COSMIC cancer mutations	skin-face-malignant_melanoma-nodular	7	1	16828	49	PREX2
2.021e-02	-3.90	skin-upper_leg-malignant_melanoma-nodular	COSMIC cancer mutations	skin-upper_leg-malignant_melanoma-nodular	7	1	16828	49	PREX2
2.021e-02	-3.90	skin-neck-other-seborrhoeic_keratosis	COSMIC cancer mutations	skin-neck-other-seborrhoeic_keratosis	7	1	16828	49	FGFR3
2.021e-02	-3.90	nevus_sebaceous	COSMIC cancer mutations	nevus_sebaceous	7	1	16828	49	FGFR3
2.021e-02	-3.90	urinary_tract-carcinoma-transitional_cell_carcinoma	COSMIC cancer mutations	urinary_tract-carcinoma-transitional_cell_carcinoma	7	1	16828	49	FGFR3
2.021e-02	-3.90	skin-benign_melanocytic_nevus-compound	COSMIC cancer mutations	skin-benign_melanocytic_nevus-compound	7	1	16828	49	FGFR3
2.034e-02	-3.90	spherical high-density lipoprotein particle	cellular component	GO:0034366	8	1	19108	49	CLU
2.034e-02	-3.90	HFE-transferrin receptor complex	cellular component	GO:1990712	8	1	19108	49	BMPR1B
2.038e-02	-3.89	DEPP1 (DEPP autophagy regulator 1)	protein interactions	11067	8	1	19454	50	QKI
2.038e-02	-3.89	Chmp2a (charged multivesicular body protein 2A)	protein interactions	68953	8	1	19454	50	CLU
2.038e-02	-3.89	CCK (cholecystokinin)	protein interactions	885	8	1	19454	50	CPE
2.038e-02	-3.89	CD163 (CD163 molecule)	protein interactions	9332	8	1	19454	50	PRKCA
2.038e-02	-3.89	LHB (luteinizing hormone subunit beta)	protein interactions	3972	8	1	19454	50	NTM
2.038e-02	-3.89	Prkca (protein kinase C, alpha)	protein interactions	24680	8	1	19454	50	PRKCA
2.038e-02	-3.89	Rasd2 (RASD family, member 2)	protein interactions	75141	8	1	19454	50	BMPR1B
2.038e-02	-3.89	Marcks (myristoylated alanine rich protein kinase C substrate)	protein interactions	17118	8	1	19454	50	PRKCA
2.038e-02	-3.89	BMP15 (bone morphogenetic protein 15)	protein interactions	9210	8	1	19454	50	BMPR1B
2.038e-02	-3.89	Rps27a (ribosomal protein S27A)	protein interactions	78294	8	1	19454	50	BMPR1B
2.051e-02	-3.89	GAR	prosite domains	PS51460	6	1	12186	42	MACF1
2.059e-02	-3.88	regulation of cell junction assembly	biological process	GO:1901888	217	3	18204	49	MACF1,NRXN1,NTRK2
2.059e-02	-3.88	ErbB Signaling Pathway	WikiPathways	WP673	54	2	5310	22	PRKCA,NRG3
2.076e-02	-3.87	Oncogenic MAPK signaling	REACTOME pathways	R-HSA-6802957	74	2	10285	31	MACF1,QKI
2.079e-02	-3.87	haematopoietic_and_lymphoid_tissue-lymph_node-lymphoid_neoplasm-diffuse_large_B_cell_lymphoma	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue-lymph_node-lymphoid_neoplasm-diffuse_large_B_cell_lymphoma	748	6	16828	49	NTRK2,SLC1A3,ITPR2,DTNA,CTNND2,SOX5
2.085e-02	-3.87	Long-term potentiation	KEGG pathways	ko04720	67	2	7161	24	ITPR2,PRKCA
2.085e-02	-3.87	Long-term potentiation	KEGG pathways	hsa04720	67	2	7161	24	ITPR2,PRKCA
2.091e-02	-3.87	FGFR3b ligand binding and activation	REACTOME pathways	R-HSA-190371	7	1	10285	31	FGFR3
2.103e-02	-3.86	BMP receptor activity	molecular function	GO:0098821	8	1	18094	48	BMPR1B
2.103e-02	-3.86	glutamate binding	molecular function	GO:0016595	8	1	18094	48	SLC1A3
2.103e-02	-3.86	sodium ion binding	molecular function	GO:0031402	8	1	18094	48	ATP1A2
2.103e-02	-3.86	P-type potassium transmembrane transporter activity	molecular function	GO:0008556	8	1	18094	48	ATP1A2
2.105e-02	-3.86	glutamatergic synapse	cellular component	GO:0098978	412	4	19108	49	NRG3,TNIK,GPM6A,SLC1A2
2.108e-02	-3.86	MIR141 (microRNA 141)	protein interactions	406933	87	2	19454	50	MSI2,QKI
2.108e-02	-3.86	NHLH1 (nescient helix-loop-helix 1)	protein interactions	4807	87	2	19454	50	NFIA,NFIB
2.120e-02	-3.85	urinary_tract-bladder-carcinoma-transitional_cell_carcinoma	COSMIC cancer mutations	urinary_tract-bladder-carcinoma-transitional_cell_carcinoma	6040	25	16828	49	ATP13A4,PARD3B,ZBTB20,FMN2,PCDH9,SFXN5,PREX2,SLC1A3,NRXN1,NTRK2,MGAT4C,ADCY2,CDH20,CLU,PTPRZ1,DTNA,NFIA,ITPR2,ATP1A2,GPM6A,FGFR3,PON2,MACF1,GLIS3,NRG3
2.123e-02	-3.85	kidney-carcinoma-clear_cell_renal_cell_carcinoma	COSMIC cancer mutations	kidney-carcinoma-clear_cell_renal_cell_carcinoma	13924	46	16828	49	DTNA,NRG3,AQP4,GPM6A,ATP1A2,FGFR3,NKAIN3,NHSL1,PTPRZ1,CPE,FBXL7,CLU,ADCY2,CSGALNACT1,SFXN5,PREX2,CTNND2,FMN2,PCDH9,ZBTB20,ITPR2,NFIA,NPAS3,QKI,GLIS3,MACF1,PRKCA,SOX5,NRXN1,NTRK2,SLC1A3,MGAT4C,SLC1A2,NFIB,CDH20,RORA,EFEMP1,LSAMP,GLUD1,PITPNC1,BMPR1B,ATP13A4,TNIK,LIFR,PARD3B,MSI2
2.123e-02	-3.85	clear_cell_renal_cell_carcinoma	COSMIC cancer mutations	clear_cell_renal_cell_carcinoma	13924	46	16828	49	CDH20,LSAMP,EFEMP1,RORA,MGAT4C,NTRK2,NRXN1,SLC1A3,NFIB,SLC1A2,PARD3B,MSI2,TNIK,LIFR,GLUD1,BMPR1B,ATP13A4,PITPNC1,PRKCA,MACF1,GLIS3,NPAS3,ITPR2,NFIA,QKI,SOX5,CLU,FBXL7,ADCY2,CTNND2,PREX2,SFXN5,ZBTB20,PCDH9,FMN2,CSGALNACT1,NRG3,FGFR3,ATP1A2,AQP4,GPM6A,DTNA,PTPRZ1,CPE,NKAIN3,NHSL1
2.123e-02	-3.85	H1-5 (H1.5 linker histone, cluster member)	protein interactions	3009	412	4	19454	50	MGAT4C,PRKCA,PARD3B,CSGALNACT1
2.127e-02	-3.85	DST (dystonin)	protein interactions	667	230	3	19454	50	ATP1A2,TNIK,NTRK2
2.128e-02	-3.85	mesothelioma	COSMIC cancer mutations	mesothelioma	4477	20	16828	49	PITPNC1,ATP13A4,BMPR1B,PTPRZ1,SOX5,CTNND2,PREX2,LIFR,TNIK,FMN2,MSI2,ITPR2,NTRK2,QKI,NFIB,PRKCA,FBXL7,CLU,RORA,FGFR3
2.129e-02	-3.85	transitional_cell_carcinoma	COSMIC cancer mutations	transitional_cell_carcinoma	6042	25	16828	49	NRXN1,SLC1A3,NTRK2,MGAT4C,ADCY2,CDH20,CLU,ATP13A4,ZBTB20,PARD3B,FMN2,PCDH9,SFXN5,PREX2,DTNA,ITPR2,NFIA,ATP1A2,GPM6A,FGFR3,PON2,GLIS3,MACF1,NRG3,PTPRZ1
2.130e-02	-3.85	leg	COSMIC cancer mutations	leg	969	7	16828	49	ZBTB20,FMN2,ATP13A4,FGFR3,PTPRZ1,NTM,NRG3
2.134e-02	-3.85	ERBB4 signaling pathway	biological process	GO:0038130	8	1	18204	49	NRG3
2.134e-02	-3.85	gamma-aminobutyric acid metabolic process	biological process	GO:0009448	8	1	18204	49	SLC1A3
2.134e-02	-3.85	insulin processing	biological process	GO:0030070	8	1	18204	49	CPE
2.134e-02	-3.85	dermatan sulfate proteoglycan biosynthetic process	biological process	GO:0050651	8	1	18204	49	CSGALNACT1
2.134e-02	-3.85	mitotic nuclear membrane disassembly	biological process	GO:0007077	8	1	18204	49	PRKCA
2.134e-02	-3.85	meiotic cytokinesis	biological process	GO:0033206	8	1	18204	49	FMN2
2.134e-02	-3.85	protein import	biological process	GO:0017038	8	1	18204	49	CLU
2.134e-02	-3.85	cell proliferation in hindbrain	biological process	GO:0021534	8	1	18204	49	RORA
2.134e-02	-3.85	glutamate catabolic process	biological process	GO:0006538	8	1	18204	49	GLUD1
2.134e-02	-3.85	cerebellar granule cell precursor proliferation	biological process	GO:0021930	8	1	18204	49	RORA
2.134e-02	-3.85	regulation of L-glutamate import across plasma membrane	biological process	GO:0002036	8	1	18204	49	ATP1A2
2.134e-02	-3.85	cell proliferation in external granule layer	biological process	GO:0021924	8	1	18204	49	RORA
2.134e-02	-3.85	type I pneumocyte differentiation	biological process	GO:0060509	8	1	18204	49	NFIB
2.134e-02	-3.85	heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process	biological process	GO:0015014	8	1	18204	49	CSGALNACT1
2.134e-02	-3.85	response to mechanical stimulus	biological process	GO:0009612	220	3	18204	49	SLC1A3,ATP1A2,NRXN1
2.140e-02	-3.84	Chond_GalNAc	interpro domains	IPR008428	8	1	18521	50	CSGALNACT1
2.140e-02	-3.84	Plakin	interpro domains	IPR043197	8	1	18521	50	MACF1
2.140e-02	-3.84	AC_N	interpro domains	IPR032628	8	1	18521	50	ADCY2
2.140e-02	-3.84	Adcy	interpro domains	IPR030672	8	1	18521	50	ADCY2
2.151e-02	-3.84	regulation of sodium ion transport	biological process	GO:0002028	84	2	18204	49	NKAIN3,ATP1A2
2.151e-02	-3.84	proteoglycan metabolic process	biological process	GO:0006029	84	2	18204	49	CSGALNACT1,BMPR1B
2.151e-02	-3.84	L-amino acid transport	biological process	GO:0015807	84	2	18204	49	SLC1A2,SLC1A3
2.153e-02	-3.84	NLGN3 (neuroligin 3)	protein interactions	54413	88	2	19454	50	NRXN1,EFEMP1
2.153e-02	-3.84	RAP2A (RAP2A, member of RAS oncogene family)	protein interactions	5911	88	2	19454	50	BMPR1B,TNIK
2.153e-02	-3.84	Ig_sub	interpro domains	IPR003599	394	4	18521	50	LSAMP,FGFR3,NTRK2,NTM
2.165e-02	-3.83	establishment of localization	biological process	GO:0051234	3887	17	18204	49	ITPR2,AQP4,MACF1,NRXN1,SLC1A3,GPM6A,CPE,CLU,NTRK2,FMN2,QKI,PARD3B,ATP13A4,SFXN5,PITPNC1,SLC1A2,ATP1A2
2.168e-02	-3.83	hairy_cell_leukaemia	COSMIC cancer mutations	hairy_cell_leukaemia	1440	9	16828	49	NRXN1,LIFR,FMN2,FGFR3,PTPRZ1,CDH20,MACF1,CTNND2,PREX2
2.168e-02	-3.83	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-hairy_cell_leukaemia	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-hairy_cell_leukaemia	1440	9	16828	49	PREX2,CTNND2,MACF1,CDH20,PTPRZ1,FGFR3,LIFR,FMN2,NRXN1
2.175e-02	-3.83	Ion Channel and Phorbal Esters Signaling Pathway	SMPDB pathways	SMP0090032	5	1	1369	6	PRKCA
2.175e-02	-3.83	Corticotropin Activation of Cortisol Production	SMPDB pathways	SMP0000310	5	1	1369	6	ADCY2
2.176e-02	-3.83	Calcium signaling pathway	KEGG pathways	hsa04020	181	3	7161	24	PRKCA,ITPR2,ADCY2
2.176e-02	-3.83	Calcium signaling pathway	KEGG pathways	ko04020	181	3	7161	24	PRKCA,ITPR2,ADCY2
2.182e-02	-3.82	AC_N	pfam domains	PF16214	8	1	17795	49	ADCY2
2.182e-02	-3.82	CHGN	pfam domains	PF05679	8	1	17795	49	CSGALNACT1
2.199e-02	-3.82	SOX10 (SRY-box transcription factor 10)	protein interactions	6663	89	2	19454	50	NFIA,NFIB
2.201e-02	-3.82	organic anion transport	biological process	GO:0015711	398	4	18204	49	SLC1A2,SLC1A3,SFXN5,NTRK2
2.208e-02	-3.81	NUP35 (nucleoporin 35)	protein interactions	129401	417	4	19454	50	GLUD1,NFIB,PON2,GLIS3
2.215e-02	-3.81	Endothelins	Pathway Interaction DB	endothelinpathway	53	2	2226	10	PRKCA,ADCY2
2.232e-02	-3.80	lung-left_upper_lobe-carcinoma-adenocarcinoma	COSMIC cancer mutations	lung-left_upper_lobe-carcinoma-adenocarcinoma	556	5	16828	49	LIFR,ADCY2,NTRK2,CTNND2,FBXL7
2.234e-02	-3.80	single-stranded RNA binding	molecular function	GO:0003727	87	2	18094	48	RBMS3,MSI2
2.236e-02	-3.80	neuron projection guidance	biological process	GO:0097485	224	3	18204	49	BMPR1B,NRXN1,NFIB
2.236e-02	-3.80	axon guidance	biological process	GO:0007411	224	3	18204	49	NFIB,NRXN1,BMPR1B
2.246e-02	-3.80	SEMG1 (semenogelin 1)	protein interactions	6406	90	2	19454	50	PRKCA,CLU
2.246e-02	-3.80	CTDSPL (CTD small phosphatase like)	protein interactions	10217	90	2	19454	50	DTNA,FMN2
2.247e-02	-3.80	central nervous system neuron development	biological process	GO:0021954	86	2	18204	49	NTRK2,NFIB
2.249e-02	-3.79	MARK3 (microtubule affinity regulating kinase 3)	protein interactions	4140	235	3	19454	50	MACF1,DTNA,NTRK2
2.262e-02	-3.79	left_upper_lobe	COSMIC cancer mutations	left_upper_lobe	558	5	16828	49	ADCY2,LIFR,FBXL7,CTNND2,NTRK2
2.268e-02	-3.79	lobular_carcinoma	COSMIC cancer mutations	lobular_carcinoma	763	6	16828	49	PRKCA,NTRK2,CDH20,FGFR3,BMPR1B,TNIK
2.268e-02	-3.79	breast-carcinoma-lobular_carcinoma	COSMIC cancer mutations	breast-carcinoma-lobular_carcinoma	763	6	16828	49	NTRK2,CDH20,PRKCA,TNIK,FGFR3,BMPR1B
2.272e-02	-3.78	human chr6q26	chromosome location	human chr6q26	12	1	26134	50	QKI
2.272e-02	-3.78	human chr3p24.1	chromosome location	human chr3p24.1	12	1	26134	50	RBMS3
2.285e-02	-3.78	astrocyte end-foot	cellular component	GO:0097450	9	1	19108	49	AQP4
2.285e-02	-3.78	platelet dense tubular network membrane	cellular component	GO:0031095	9	1	19108	49	ITPR2
2.290e-02	-3.78	ZNF778 (zinc finger protein 778)	protein interactions	197320	9	1	19454	50	EFEMP1
2.290e-02	-3.78	NRXN2 (neurexin 2)	protein interactions	9379	9	1	19454	50	MACF1
2.290e-02	-3.78	VEPH1 (ventricular zone expressed PH domain containing 1)	protein interactions	79674	9	1	19454	50	BMPR1B
2.290e-02	-3.78	KLB (klotho beta)	protein interactions	152831	9	1	19454	50	FGFR3
2.290e-02	-3.78	Ywhag (tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide)	protein interactions	22628	9	1	19454	50	QKI
2.290e-02	-3.78	SCTR (secretin receptor)	protein interactions	6344	9	1	19454	50	PRKCA
2.290e-02	-3.78	BIN2 (bridging integrator 2)	protein interactions	51411	9	1	19454	50	EFEMP1
2.290e-02	-3.78	GUSBP1 (GUSB pseudogene 1)	protein interactions	728411	9	1	19454	50	FGFR3
2.292e-02	-3.78	DGUOK (deoxyguanosine kinase)	protein interactions	1716	91	2	19454	50	GPM6A,NTM
2.299e-02	-3.77	CAMK2A (calcium/calmodulin dependent protein kinase II alpha)	protein interactions	815	237	3	19454	50	SOX5,GPM6A,ITPR2
2.306e-02	-3.77	actinic_keratosis	COSMIC cancer mutations	actinic_keratosis	8	1	16828	49	FGFR3
2.306e-02	-3.77	skin-chest-malignant_melanoma-nodular	COSMIC cancer mutations	skin-chest-malignant_melanoma-nodular	8	1	16828	49	PREX2
2.306e-02	-3.77	cervix-in_situ_neoplasm-cervical_intraepithelial_neoplasia_Grade_I	COSMIC cancer mutations	cervix-in_situ_neoplasm-cervical_intraepithelial_neoplasia_Grade_I	8	1	16828	49	FGFR3
2.306e-02	-3.77	cervical_intraepithelial_neoplasia_Grade_I	COSMIC cancer mutations	cervical_intraepithelial_neoplasia_Grade_I	8	1	16828	49	FGFR3
2.306e-02	-3.77	urinary_tract-ureter-carcinoma-transitional_cell_carcinoma	COSMIC cancer mutations	urinary_tract-ureter-carcinoma-transitional_cell_carcinoma	8	1	16828	49	FGFR3
2.306e-02	-3.77	central_nervous_system-chiasm-glioma-astrocytoma_Grade_I	COSMIC cancer mutations	central_nervous_system-chiasm-glioma-astrocytoma_Grade_I	8	1	16828	49	QKI
2.306e-02	-3.77	trichoblastoma	COSMIC cancer mutations	trichoblastoma	8	1	16828	49	FGFR3
2.306e-02	-3.77	junctional	COSMIC cancer mutations	junctional	8	1	16828	49	FGFR3
2.309e-02	-3.77	salivary_gland-parotid-carcinoma-adenoid_cystic_carcinoma	COSMIC cancer mutations	salivary_gland-parotid-carcinoma-adenoid_cystic_carcinoma	561	5	16828	49	FGFR3,LIFR,TNIK,PRKCA,NTRK2
2.324e-02	-3.76	GAS2	smart domains	SM00243	6	1	9717	38	MACF1
2.325e-02	-3.76	forearm	COSMIC cancer mutations	forearm	81	2	16828	49	FGFR3,PREX2
2.336e-02	-3.76	Calcium Regulation in the Cardiac Cell	WikiPathways	WP536	151	3	5310	22	ADCY2,ITPR2,PRKCA
2.339e-02	-3.76	FNTA (farnesyltransferase, CAAX box, subunit alpha)	protein interactions	2339	92	2	19454	50	FGFR3,TNIK
2.339e-02	-3.76	POTEI (POTE ankyrin domain family member I)	protein interactions	653269	92	2	19454	50	FGFR3,DTNA
2.339e-02	-3.76	DPF1 (double PHD fingers 1)	protein interactions	8193	92	2	19454	50	NFIA,NFIB
2.339e-02	-3.76	RLN1 (relaxin 1)	protein interactions	6013	92	2	19454	50	PON2,CPE
2.363e-02	-3.75	calcium-dependent protein serine/threonine kinase activity	molecular function	GO:0009931	9	1	18094	48	PRKCA
2.380e-02	-3.74	PROTEIN_KINASE_DOM	prosite domains	PS50011	480	5	12186	42	TNIK,PRKCA,FGFR3,BMPR1B,NTRK2
2.387e-02	-3.74	Diseases of signal transduction	REACTOME pathways	R-HSA-5663202	369	4	10285	31	FGFR3,NRG3,QKI,MACF1
2.387e-02	-3.74	HuR (ELAVL1) binds and stabilizes mRNA	REACTOME pathways	R-HSA-450520	8	1	10285	31	PRKCA
2.387e-02	-3.74	transport	biological process	GO:0006810	3615	16	18204	49	ATP1A2,SLC1A2,PITPNC1,SFXN5,ATP13A4,QKI,FMN2,NTRK2,CLU,SLC1A3,CPE,GPM6A,NRXN1,MACF1,AQP4,ITPR2
2.387e-02	-3.74	MIR19B2 (microRNA 19b-2)	protein interactions	406981	93	2	19454	50	QKI,MSI2
2.387e-02	-3.74	DMRTB1 (DMRT like family B with proline rich C-terminal 1)	protein interactions	63948	93	2	19454	50	QKI,MSI2
2.387e-02	-3.74	TEX11 (testis expressed 11)	protein interactions	56159	93	2	19454	50	SOX5,QKI
2.388e-02	-3.73	ACTIVIN2R	prints domains	PR00653	6	1	5227	21	BMPR1B
2.388e-02	-3.73	HEMATOPO_REC_L_F2	prosite domains	PS01353	7	1	12186	42	LIFR
2.388e-02	-3.73	GS	prosite domains	PS51256	7	1	12186	42	BMPR1B
2.395e-02	-3.73	cell fate specification	biological process	GO:0001708	89	2	18204	49	NFIB,NFIA
2.397e-02	-3.73	positive regulation of synapse maturation	biological process	GO:0090129	9	1	18204	49	NRXN1
2.397e-02	-3.73	macrophage proliferation	biological process	GO:0061517	9	1	18204	49	CLU
2.397e-02	-3.73	microglial cell proliferation	biological process	GO:0061518	9	1	18204	49	CLU
2.397e-02	-3.73	polyamine transmembrane transport	biological process	GO:1902047	9	1	18204	49	ATP13A4
2.397e-02	-3.73	negative regulation of striated muscle contraction	biological process	GO:0045988	9	1	18204	49	ATP1A2
2.401e-02	-3.73	Regulation of insulin secretion	REACTOME pathways	R-HSA-422356	80	2	10285	31	ITPR2,PRKCA
2.404e-02	-3.73	Activin_recp	interpro domains	IPR000472	9	1	18521	50	BMPR1B
2.404e-02	-3.73	Aminoacid_DH-like_N_sf	interpro domains	IPR046346	9	1	18521	50	GLUD1
2.405e-02	-3.73	atypical_teratoid-rhabdoid_tumour	COSMIC cancer mutations	atypical_teratoid-rhabdoid_tumour	213	3	16828	49	FGFR3,PCDH9,FMN2
2.405e-02	-3.73	central_nervous_system-brain-atypical_teratoid-rhabdoid_tumour	COSMIC cancer mutations	central_nervous_system-brain-atypical_teratoid-rhabdoid_tumour	213	3	16828	49	FGFR3,FMN2,PCDH9
2.410e-02	-3.73	upper_aerodigestive_tract-mouth-carcinoma	COSMIC cancer mutations	upper_aerodigestive_tract-mouth-carcinoma	6426	26	16828	49	NRG3,MACF1,FGFR3,GPM6A,NPAS3,QKI,SOX5,NHSL1,FBXL7,CLU,CDH20,NTM,ADCY2,RORA,EFEMP1,MGAT4C,SLC1A3,SLC1A2,PREX2,CTNND2,SFXN5,FMN2,LIFR,ZBTB20,PARD3B,PITPNC1
2.411e-02	-3.73	intracellular signaling cassette	biological process	GO:0141124	837	6	18204	49	ADCY2,FGFR3,ATP1A2,PREX2,TNIK,ITPR2
2.435e-02	-3.72	QSER1 (glutamine and serine rich 1)	protein interactions	79832	94	2	19454	50	SOX5,NFIA
2.435e-02	-3.72	TTR (transthyretin)	protein interactions	7276	94	2	19454	50	CTNND2,CLU
2.435e-02	-3.72	WWC1 (WW and C2 domain containing 1)	protein interactions	23286	94	2	19454	50	TNIK,PRKCA
2.438e-02	-3.71	postsynapse	cellular component	GO:0098794	646	5	19108	49	NTRK2,CTNND2,TNIK,GPM6A,ATP1A2
2.452e-02	-3.71	Activin_recp	pfam domains	PF01064	9	1	17795	49	BMPR1B
2.459e-02	-3.71	human chr5p15.1	chromosome location	human chr5p15.1	13	1	26134	50	FBXL7
2.470e-02	-3.70	EGF-like_dom	interpro domains	IPR000742	232	3	18521	50	EFEMP1,NRXN1,NRG3
2.484e-02	-3.70	vesicle	cellular component	GO:0031982	4141	17	19108	49	TNIK,AQP4,ATP1A2,LIFR,EFEMP1,GPM6A,SLC1A2,ITPR2,NRXN1,CLU,FMN2,SLC1A3,PRKCA,ATP13A4,CPE,FGFR3,NTRK2
2.487e-02	-3.69	response to organic cyclic compound	biological process	GO:0014070	843	6	18204	49	ITPR2,SLC1A3,ATP1A2,SLC1A2,ADCY2,RORA
2.489e-02	-3.69	adenyl nucleotide binding	molecular function	GO:0030554	1620	9	18094	48	PRKCA,GLUD1,ATP13A4,TNIK,ADCY2,FGFR3,BMPR1B,NTRK2,ATP1A2
2.496e-02	-3.69	cellular response to BMP stimulus	biological process	GO:0071773	91	2	18204	49	BMPR1B,NFIA
2.496e-02	-3.69	response to BMP	biological process	GO:0071772	91	2	18204	49	BMPR1B,NFIA
2.519e-02	-3.68	chemical synaptic transmission	biological process	GO:0007268	415	4	18204	49	SLC1A3,SLC1A2,NRXN1,DTNA
2.519e-02	-3.68	anterograde trans-synaptic signaling	biological process	GO:0098916	415	4	18204	49	NRXN1,DTNA,SLC1A2,SLC1A3
2.523e-02	-3.68	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-NK-T_cell_lymphoma	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-NK-T_cell_lymphoma	217	3	16828	49	DTNA,MGAT4C,PON2
2.532e-02	-3.68	RLIM (ring finger protein, LIM domain interacting)	protein interactions	51132	96	2	19454	50	NFIA,NFIB
2.536e-02	-3.67	perineuronal net	cellular component	GO:0072534	10	1	19108	49	PTPRZ1
2.541e-02	-3.67	GSG1 (germ cell associated 1)	protein interactions	83445	10	1	19454	50	PITPNC1
2.541e-02	-3.67	CALB2 (calbindin 2)	protein interactions	794	10	1	19454	50	GPM6A
2.541e-02	-3.67	SLC8A2 (solute carrier family 8 member A2)	protein interactions	6543	10	1	19454	50	GPM6A
2.541e-02	-3.67	BANK1 (B cell scaffold protein with ankyrin repeats 1)	protein interactions	55024	10	1	19454	50	ITPR2
2.541e-02	-3.67	TNP1 (transition protein 1)	protein interactions	7141	10	1	19454	50	PRKCA
2.541e-02	-3.67	Smurf2 (SMAD specific E3 ubiquitin protein ligase 2)	protein interactions	66313	10	1	19454	50	GLIS3
2.541e-02	-3.67	P2rx7 (purinergic receptor P2X 7)	protein interactions	29665	10	1	19454	50	PTPRZ1
2.541e-02	-3.67	SERPINB11 (serpin family B member 11)	protein interactions	89778	10	1	19454	50	CPE
2.541e-02	-3.67	Mrpl13 (mitochondrial ribosomal protein L13)	protein interactions	68537	10	1	19454	50	QKI
2.541e-02	-3.67	Hsp90aa1 (heat shock protein 90, alpha (cytosolic), class A member 1)	protein interactions	15519	10	1	19454	50	QKI
2.541e-02	-3.67	ALKAL2 (ALK and LTK ligand 2)	protein interactions	285016	10	1	19454	50	PON2
2.541e-02	-3.67	PPY (pancreatic polypeptide)	protein interactions	5539	10	1	19454	50	PRKCA
2.566e-02	-3.66	adrenal_cortical_carcinoma	COSMIC cancer mutations	adrenal_cortical_carcinoma	2256	12	16828	49	ATP1A2,EFEMP1,NRG3,SLC1A2,NTRK2,ZBTB20,PCDH9,FMN2,CTNND2,SOX5,PTPRZ1,NHSL1
2.586e-02	-3.66	parotid	COSMIC cancer mutations	parotid	578	5	16828	49	NTRK2,PRKCA,LIFR,TNIK,FGFR3
2.589e-02	-3.65	shoulder	COSMIC cancer mutations	shoulder	387	4	16828	49	MACF1,PREX2,CPE,FGFR3
2.591e-02	-3.65	epidermal_nevus	COSMIC cancer mutations	epidermal_nevus	9	1	16828	49	FGFR3
2.591e-02	-3.65	ovary-low_malignant_potential_(borderline)_tumour-Brenner_tumour	COSMIC cancer mutations	ovary-low_malignant_potential_(borderline)_tumour-Brenner_tumour	9	1	16828	49	FGFR3
2.591e-02	-3.65	in_situ_epithelial_neoplasm	COSMIC cancer mutations	in_situ_epithelial_neoplasm	9	1	16828	49	FGFR3
2.591e-02	-3.65	skin-upper_leg-malignant_melanoma-superficial_spreading	COSMIC cancer mutations	skin-upper_leg-malignant_melanoma-superficial_spreading	9	1	16828	49	PREX2
2.591e-02	-3.65	skin-benign_melanocytic_nevus-congenital	COSMIC cancer mutations	skin-benign_melanocytic_nevus-congenital	9	1	16828	49	FGFR3
2.591e-02	-3.65	Bowen_disease	COSMIC cancer mutations	Bowen_disease	9	1	16828	49	FGFR3
2.591e-02	-3.65	skin-other-seborrhoeic_keratosis	COSMIC cancer mutations	skin-other-seborrhoeic_keratosis	9	1	16828	49	FGFR3
2.591e-02	-3.65	skin-chest-malignant_melanoma-superficial_spreading	COSMIC cancer mutations	skin-chest-malignant_melanoma-superficial_spreading	9	1	16828	49	PREX2
2.591e-02	-3.65	compound	COSMIC cancer mutations	compound	9	1	16828	49	FGFR3
2.593e-02	-3.65	Laminin	gene3d domains	2.10.25.10	226	3	14470	41	NRXN1,NRG3,EFEMP1
2.606e-02	-3.65	Dopamine Activation of Neurological Reward System	SMPDB pathways	SMP0000308	6	1	1369	6	ADCY2
2.606e-02	-3.65	Phospholipase C Signaling Pathway	SMPDB pathways	SMP0063783	6	1	1369	6	PRKCA
2.606e-02	-3.65	Intracellular Signalling Through PGD2 receptor and Prostaglandin D2	SMPDB pathways	SMP0000343	6	1	1369	6	ADCY2
2.618e-02	-3.64	axon development	biological process	GO:0061564	420	4	18204	49	PTPRZ1,BMPR1B,NRXN1,NFIB
2.621e-02	-3.64	oesophagus-carcinoma-adenocarcinoma	COSMIC cancer mutations	oesophagus-carcinoma-adenocarcinoma	13112	44	16828	49	NPAS3,ITPR2,QKI,PRKCA,GLIS3,MACF1,SOX5,MGAT4C,NRXN1,SLC1A3,NTRK2,NFIB,SLC1A2,CDH20,LSAMP,RORA,EFEMP1,GLUD1,ATP13A4,BMPR1B,PARD3B,LIFR,TNIK,NRG3,PON2,FGFR3,ATP1A2,GPM6A,AQP4,NKAIN3,NHSL1,PTPRZ1,CPE,CLU,FBXL7,NTM,ADCY2,CSGALNACT1,PREX2,CTNND2,SFXN5,ZBTB20,PCDH9,FMN2
2.622e-02	-3.64	neurotrophin binding	molecular function	GO:0043121	10	1	18094	48	NTRK2
2.622e-02	-3.64	phosphatidylinositol transfer activity	molecular function	GO:0008526	10	1	18094	48	PITPNC1
2.622e-02	-3.64	calcium-dependent protein kinase activity	molecular function	GO:0010857	10	1	18094	48	PRKCA
2.622e-02	-3.64	polyamine transmembrane transporter activity	molecular function	GO:0015203	10	1	18094	48	ATP13A4
2.629e-02	-3.64	Myometrial Relaxation and Contraction Pathways	WikiPathways	WP289	158	3	5310	22	ADCY2,ITPR2,PRKCA
2.631e-02	-3.64	MED27 (mediator complex subunit 27)	protein interactions	9442	98	2	19454	50	QKI,SOX5
2.631e-02	-3.64	DNAAF2 (dynein axonemal assembly factor 2)	protein interactions	55172	98	2	19454	50	GPM6A,LSAMP
2.631e-02	-3.64	FRS2 (fibroblast growth factor receptor substrate 2)	protein interactions	10818	98	2	19454	50	FGFR3,NTRK2
2.645e-02	-3.63	dermatan sulfate biosynthesis	BIOCYC pathways	HUMAN_PWY-6571	12	1	902	2	CSGALNACT1
2.646e-02	-3.63	human chr2p16.3	chromosome location	human chr2p16.3	14	1	26134	50	NRXN1
2.646e-02	-3.63	human chr2p13.2	chromosome location	human chr2p13.2	14	1	26134	50	SFXN5
2.654e-02	-3.63	upper_arm	COSMIC cancer mutations	upper_arm	582	5	16828	49	ITPR2,PREX2,FMN2,PARD3B,FGFR3
2.660e-02	-3.63	desmosome organization	biological process	GO:0002934	10	1	18204	49	PRKCA
2.660e-02	-3.63	positive regulation of lipopolysaccharide-mediated signaling pathway	biological process	GO:0031666	10	1	18204	49	PRKCA
2.660e-02	-3.63	postsynaptic density assembly	biological process	GO:0097107	10	1	18204	49	NRXN1
2.660e-02	-3.63	substrate-independent telencephalic tangential migration	biological process	GO:0021826	10	1	18204	49	NRG3
2.660e-02	-3.63	learned vocalization behavior or vocal learning	biological process	GO:0098598	10	1	18204	49	NRXN1
2.660e-02	-3.63	cAMP biosynthetic process	biological process	GO:0006171	10	1	18204	49	ADCY2
2.660e-02	-3.63	regulation of mesenchymal stem cell differentiation	biological process	GO:2000739	10	1	18204	49	SOX5
2.660e-02	-3.63	trans-synaptic signaling, modulating synaptic transmission	biological process	GO:0099550	10	1	18204	49	NTRK2
2.660e-02	-3.63	negative regulation of glial cell apoptotic process	biological process	GO:0034351	10	1	18204	49	PRKCA
2.660e-02	-3.63	substrate-independent telencephalic tangential interneuron migration	biological process	GO:0021843	10	1	18204	49	NRG3
2.660e-02	-3.63	lung secretory cell differentiation	biological process	GO:0061140	10	1	18204	49	NFIB
2.660e-02	-3.63	establishment of centrosome localization	biological process	GO:0051660	10	1	18204	49	PARD3B
2.660e-02	-3.63	retinal rod cell development	biological process	GO:0046548	10	1	18204	49	NTRK2
2.660e-02	-3.63	postsynaptic membrane assembly	biological process	GO:0097104	10	1	18204	49	NRXN1
2.660e-02	-3.63	cellular response to brain-derived neurotrophic factor stimulus	biological process	GO:1990416	10	1	18204	49	NTRK2
2.666e-02	-3.62	TGFBR1 (transforming growth factor beta receptor 1)	protein interactions	7046	251	3	19454	50	CLU,PREX2,BMPR1B
2.668e-02	-3.62	MIP_CS	interpro domains	IPR022357	10	1	18521	50	AQP4
2.668e-02	-3.62	PAS_fold_3	interpro domains	IPR013655	10	1	18521	50	NPAS3
2.668e-02	-3.62	MIR_motif	interpro domains	IPR016093	10	1	18521	50	ITPR2
2.668e-02	-3.62	MIR_dom_sf	interpro domains	IPR036300	10	1	18521	50	ITPR2
2.680e-02	-3.62	TNKS (tankyrase)	protein interactions	8658	99	2	19454	50	TNIK,PCDH9
2.681e-02	-3.62	Synthesis of 5-eicosatetraenoic acids	REACTOME pathways	R-HSA-2142688	9	1	10285	31	PON2
2.681e-02	-3.62	Terminal pathway of complement	REACTOME pathways	R-HSA-166665	9	1	10285	31	CLU
2.681e-02	-3.62	EGFR Transactivation by Gastrin	REACTOME pathways	R-HSA-2179392	9	1	10285	31	PRKCA
2.683e-02	-3.62	ATPase-coupled transmembrane transporter activity	molecular function	GO:0042626	96	2	18094	48	ATP1A2,ATP13A4
2.691e-02	-3.62	response to abiotic stimulus	biological process	GO:0009628	1100	7	18204	49	NRXN1,ITPR2,FMN2,SLC1A3,ATP1A2,SLC1A2,RORA
2.693e-02	-3.61	NCK2 (NCK adaptor protein 2)	protein interactions	8440	252	3	19454	50	NTRK2,TNIK,NHSL1
2.701e-02	-3.61	anchoring junction	cellular component	GO:0070161	902	6	19108	49	ATP1A2,FGFR3,PCDH9,PARD3B,CTNND2,CDH20
2.702e-02	-3.61	biliary_tract-gallbladder-carcinoma-adenocarcinoma	COSMIC cancer mutations	biliary_tract-gallbladder-carcinoma-adenocarcinoma	2821	14	16828	49	ITPR2,NRG3,CLU,MACF1,FGFR3,NKAIN3,NHSL1,PITPNC1,PREX2,CTNND2,PTPRZ1,FMN2,PCDH9,TNIK
2.702e-02	-3.61	gallbladder	COSMIC cancer mutations	gallbladder	2821	14	16828	49	ITPR2,MACF1,CLU,NRG3,FGFR3,NKAIN3,PITPNC1,NHSL1,PTPRZ1,PREX2,CTNND2,TNIK,FMN2,PCDH9
2.706e-02	-3.61	PLEC	smart domains	SM00250	7	1	9717	38	MACF1
2.706e-02	-3.61	GS	smart domains	SM00467	7	1	9717	38	BMPR1B
2.719e-02	-3.61	extrinsic component of plasma membrane	cellular component	GO:0019897	100	2	19108	49	CDH20,DTNA
2.719e-02	-3.60	Tyr_kinase_AS	interpro domains	IPR008266	95	2	18521	50	FGFR3,NTRK2
2.719e-02	-3.60	EGF-type_Asp/Asn_hydroxyl_site	interpro domains	IPR000152	95	2	18521	50	NRXN1,EFEMP1
2.720e-02	-3.60	MIR	pfam domains	PF02815	10	1	17795	49	ITPR2
2.720e-02	-3.60	PAS_3	pfam domains	PF08447	10	1	17795	49	NPAS3
2.731e-02	-3.60	ATP4A (ATPase H+/K+ transporting subunit alpha)	protein interactions	495	100	2	19454	50	ATP1A2,GPM6A
2.731e-02	-3.60	MIDEAS (mitotic deacetylase associated SANT domain protein)	protein interactions	91748	100	2	19454	50	NFIB,NFIA
2.738e-02	-3.60	regulation of cell differentiation	biological process	GO:0045595	1622	9	18204	49	RORA,BMPR1B,PRKCA,MACF1,QKI,SOX5,PTPRZ1,NTRK2,EFEMP1
2.758e-02	-3.59	monoatomic cation transmembrane transport	biological process	GO:0098655	636	5	18204	49	ITPR2,ATP13A4,ATP1A2,SLC1A3,GPM6A
2.769e-02	-3.59	NK-T_cell_lymphoma	COSMIC cancer mutations	NK-T_cell_lymphoma	225	3	16828	49	PON2,MGAT4C,DTNA
2.780e-02	-3.58	cell surface receptor protein tyrosine kinase signaling pathway	biological process	GO:0007169	428	4	18204	49	NRG3,NTRK2,EFEMP1,FGFR3
2.780e-02	-3.58	HUDSXLRNA	prints domains	PR00961	7	1	5227	21	RBMS3
2.781e-02	-3.58	Tubg1 (tubulin, gamma 1)	protein interactions	103733	101	2	19454	50	PON2,GLUD1
2.786e-02	-3.58	perisynaptic extracellular matrix	cellular component	GO:0098966	11	1	19108	49	PTPRZ1
2.786e-02	-3.58	platelet dense tubular network	cellular component	GO:0031094	11	1	19108	49	ITPR2
2.788e-02	-3.58	regulation of neuron apoptotic process	biological process	GO:0043523	244	3	18204	49	CLU,NTRK2,PTPRZ1
2.792e-02	-3.58	IRAG1 (inositol 1,4,5-triphosphate receptor associated 1)	protein interactions	10335	11	1	19454	50	ITPR2
2.792e-02	-3.58	SYTL1 (synaptotagmin like 1)	protein interactions	84958	11	1	19454	50	NRXN1
2.792e-02	-3.58	SYN3 (synapsin III)	protein interactions	8224	11	1	19454	50	GPM6A
2.792e-02	-3.58	MSRB1 (methionine sulfoxide reductase B1)	protein interactions	51734	11	1	19454	50	CLU
2.792e-02	-3.58	AQP5 (aquaporin 5)	protein interactions	362	11	1	19454	50	ATP1A2
2.792e-02	-3.58	NTS (neurotensin)	protein interactions	4922	11	1	19454	50	CPE
2.792e-02	-3.58	CCDC17 (coiled-coil domain containing 17)	protein interactions	149483	11	1	19454	50	FGFR3
2.792e-02	-3.58	IL7 (interleukin 7)	protein interactions	3574	11	1	19454	50	QKI
2.792e-02	-3.58	Batf3 (basic leucine zipper transcription factor, ATF-like 3)	protein interactions	381319	11	1	19454	50	MACF1
2.792e-02	-3.58	DAZ1 (deleted in azoospermia 1)	protein interactions	1617	11	1	19454	50	QKI
2.792e-02	-3.58	ITPKA (inositol-trisphosphate 3-kinase A)	protein interactions	3706	11	1	19454	50	PRKCA
2.792e-02	-3.58	Gtf2e2 (general transcription factor II E, polypeptide 2 (beta subunit))	protein interactions	68153	11	1	19454	50	NHSL1
2.792e-02	-3.58	TMEM53 (transmembrane protein 53)	protein interactions	79639	11	1	19454	50	PRKCA
2.792e-02	-3.58	Wipi2 (WD repeat domain, phosphoinositide interacting 2)	protein interactions	74781	11	1	19454	50	MACF1
2.806e-02	-3.57	PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling	REACTOME pathways	R-HSA-6811558	87	2	10285	31	NRG3,FGFR3
2.810e-02	-3.57	amino acid transmembrane transport	biological process	GO:0003333	97	2	18204	49	SLC1A2,SLC1A3
2.814e-02	-3.57	PROKAR_LIPOPROTEIN	prosite domains	PS51257	76	2	12186	42	CPE,GLIS3
2.832e-02	-3.56	human chr8q12.3	chromosome location	human chr8q12.3	15	1	26134	50	NKAIN3
2.832e-02	-3.56	KRTAP6-1 (keratin associated protein 6-1)	protein interactions	337966	102	2	19454	50	GLIS3,EFEMP1
2.832e-02	-3.56	MIR7-1 (microRNA 7-1)	protein interactions	407043	102	2	19454	50	QKI,MSI2
2.835e-02	-3.56	EGFR tyrosine kinase inhibitor resistance	KEGG pathways	hsa01521	79	2	7161	24	PRKCA,FGFR3
2.835e-02	-3.56	EGFR tyrosine kinase inhibitor resistance	KEGG pathways	ko01521	79	2	7161	24	PRKCA,FGFR3
2.847e-02	-3.56	regulation of synapse organization	biological process	GO:0050807	246	3	18204	49	GPM6A,NRXN1,NTRK2
2.860e-02	-3.55	PLCG1 (phospholipase C gamma 1)	protein interactions	5335	258	3	19454	50	FGFR3,NTRK2,LIFR
2.862e-02	-3.55	pleura	COSMIC cancer mutations	pleura	4914	21	16828	49	MSI2,LIFR,TNIK,FMN2,PTPRZ1,CTNND2,PREX2,SOX5,PITPNC1,ATP13A4,BMPR1B,RORA,FGFR3,NTM,CLU,FBXL7,PRKCA,NFIB,QKI,NTRK2,ITPR2
2.875e-02	-3.55	renal_cell_carcinoma_unclassified	COSMIC cancer mutations	renal_cell_carcinoma_unclassified	10	1	16828	49	FGFR3
2.875e-02	-3.55	intradermal	COSMIC cancer mutations	intradermal	10	1	16828	49	FGFR3
2.875e-02	-3.55	kidney-carcinoma-renal_cell_carcinoma_unclassified	COSMIC cancer mutations	kidney-carcinoma-renal_cell_carcinoma_unclassified	10	1	16828	49	FGFR3
2.875e-02	-3.55	cervical_intraepithelial_neoplasia_Grade_III	COSMIC cancer mutations	cervical_intraepithelial_neoplasia_Grade_III	10	1	16828	49	FGFR3
2.875e-02	-3.55	lung-carcinoma-pleomorphic_carcinoma	COSMIC cancer mutations	lung-carcinoma-pleomorphic_carcinoma	10	1	16828	49	FGFR3
2.875e-02	-3.55	chiasm	COSMIC cancer mutations	chiasm	10	1	16828	49	QKI
2.875e-02	-3.55	skin-back-malignant_melanoma-nodular	COSMIC cancer mutations	skin-back-malignant_melanoma-nodular	10	1	16828	49	PREX2
2.875e-02	-3.55	cervix-in_situ_neoplasm-cervical_intraepithelial_neoplasia_Grade_III	COSMIC cancer mutations	cervix-in_situ_neoplasm-cervical_intraepithelial_neoplasia_Grade_III	10	1	16828	49	FGFR3
2.880e-02	-3.55	acetylcholine receptor binding	molecular function	GO:0033130	11	1	18094	48	NRXN1
2.880e-02	-3.55	histone H3 kinase activity	molecular function	GO:0140996	11	1	18094	48	PRKCA
2.880e-02	-3.55	sulfur amino acid transmembrane transporter activity	molecular function	GO:0000099	11	1	18094	48	SLC1A2
2.884e-02	-3.55	RAB6B (RAB6B, member RAS oncogene family)	protein interactions	51560	103	2	19454	50	GPM6A,BMPR1B
2.884e-02	-3.55	CSGALNACT2 (chondroitin sulfate N-acetylgalactosaminyltransferase 2)	protein interactions	55454	103	2	19454	50	MGAT4C,CSGALNACT1
2.893e-02	-3.54	amino acid transmembrane transporter activity	molecular function	GO:0015171	100	2	18094	48	SLC1A3,SLC1A2
2.894e-02	-3.54	Ig-like_dom	interpro domains	IPR007110	432	4	18521	50	NTM,NTRK2,FGFR3,LSAMP
2.912e-02	-3.54	Endochondral Ossification	WikiPathways	WP474	65	2	5310	22	SOX5,FGFR3
2.922e-02	-3.53	ectodermal placode formation	biological process	GO:0060788	11	1	18204	49	NRG3
2.922e-02	-3.53	antral ovarian follicle growth	biological process	GO:0001547	11	1	18204	49	BMPR1B
2.922e-02	-3.53	heparin biosynthetic process	biological process	GO:0030210	11	1	18204	49	CSGALNACT1
2.922e-02	-3.53	intracellular mRNA localization	biological process	GO:0008298	11	1	18204	49	QKI
2.922e-02	-3.53	negative regulation of neuron migration	biological process	GO:2001223	11	1	18204	49	NRG3
2.922e-02	-3.53	polyamine transport	biological process	GO:0015846	11	1	18204	49	ATP13A4
2.922e-02	-3.53	glutamate secretion	biological process	GO:0014047	11	1	18204	49	NTRK2
2.922e-02	-3.53	establishment or maintenance of transmembrane electrochemical gradient	biological process	GO:0010248	11	1	18204	49	ATP1A2
2.922e-02	-3.53	lactone metabolic process	biological process	GO:1901334	11	1	18204	49	ATP1A2
2.922e-02	-3.53	ectodermal placode morphogenesis	biological process	GO:0071697	11	1	18204	49	NRG3
2.922e-02	-3.53	L-ascorbic acid metabolic process	biological process	GO:0019852	11	1	18204	49	ATP1A2
2.927e-02	-3.53	blood vessel morphogenesis	biological process	GO:0048514	435	4	18204	49	NTRK2,QKI,RORA,PRKCA
2.931e-02	-3.53	Tyr_kinase_rcpt_2_CS	interpro domains	IPR002011	11	1	18521	50	NTRK2
2.946e-02	-3.52	DIRAS3 (DIRAS family GTPase 3)	protein interactions	9077	261	3	19454	50	DTNA,MACF1,FMN2
2.972e-02	-3.52	kidney-carcinoma	COSMIC cancer mutations	kidney-carcinoma	3720	17	16828	49	FBXL7,PRKCA,FGFR3,RORA,NTRK2,ITPR2,NFIB,QKI,PREX2,CTNND2,SOX5,PTPRZ1,MSI2,LIFR,TNIK,BMPR1B,PITPNC1
2.972e-02	-3.52	response to alkaloid	biological process	GO:0043279	100	2	18204	49	SLC1A3,SLC1A2
2.972e-02	-3.52	EGF_3	prosite domains	PS50026	196	3	12186	42	NRG3,NRXN1,EFEMP1
2.975e-02	-3.51	PI3K events in ERBB4 signaling	REACTOME pathways	R-HSA-1250342	10	1	10285	31	NRG3
2.975e-02	-3.51	Signaling by FGFR3 fusions in cancer	REACTOME pathways	R-HSA-8853334	10	1	10285	31	FGFR3
2.975e-02	-3.51	Acetylcholine regulates insulin secretion	REACTOME pathways	R-HSA-399997	10	1	10285	31	PRKCA
2.975e-02	-3.51	Adenylate cyclase activating pathway	REACTOME pathways	R-HSA-170660	10	1	10285	31	ADCY2
2.979e-02	-3.51	active transmembrane transporter activity	molecular function	GO:0022804	444	4	18094	48	SLC1A2,SLC1A3,ATP13A4,ATP1A2
2.988e-02	-3.51	PI3K/AKT Signaling in Cancer	REACTOME pathways	R-HSA-2219528	90	2	10285	31	NRG3,FGFR3
2.988e-02	-3.51	IRF2BP2 (interferon regulatory factor 2 binding protein 2)	protein interactions	359948	105	2	19454	50	NFIA,NFIB
2.988e-02	-3.51	ABCA2 (ATP binding cassette subfamily A member 2)	protein interactions	20	105	2	19454	50	FGFR3,PON2
2.995e-02	-3.51	Oncostatin M Signaling Pathway	WikiPathways	WP2374	66	2	5310	22	PRKCA,LIFR
3.027e-02	-3.50	regulation of synapse structure or activity	biological process	GO:0050803	252	3	18204	49	NTRK2,NRXN1,GPM6A
3.030e-02	-3.50	abdomen	COSMIC cancer mutations	abdomen	603	5	16828	49	PREX2,CTNND2,ITPR2,FGFR3,FMN2
3.034e-02	-3.50	Vasopressin Regulation of Water Homeostasis	SMPDB pathways	SMP0000322	7	1	1369	6	ADCY2
3.034e-02	-3.50	g-Secretase Mediated ErbB4 Signalling Pathway	SMPDB pathways	SMP0089975	7	1	1369	6	PRKCA
3.035e-02	-3.49	positive regulation of developmental process	biological process	GO:0051094	1385	8	18204	49	NTRK2,PTPRZ1,SOX5,QKI,PRKCA,MACF1,NRXN1,BMPR1B
3.035e-02	-3.49	synapse-associated extracellular matrix	cellular component	GO:0099535	12	1	19108	49	PTPRZ1
3.035e-02	-3.49	sodium:potassium-exchanging ATPase complex	cellular component	GO:0005890	12	1	19108	49	ATP1A2
3.036e-02	-3.49	NRAS (NRAS proto-oncogene, GTPase)	protein interactions	4893	683	5	19454	50	TNIK,SLC1A3,FMN2,MACF1,PCDH9
3.040e-02	-3.49	USP30 (ubiquitin specific peptidase 30)	protein interactions	84749	106	2	19454	50	FGFR3,QKI
3.040e-02	-3.49	ARID3B (AT-rich interaction domain 3B)	protein interactions	10620	106	2	19454	50	NFIA,NFIB
3.042e-02	-3.49	TREM2 (triggering receptor expressed on myeloid cells 2)	protein interactions	54209	12	1	19454	50	CLU
3.042e-02	-3.49	MMP25 (matrix metallopeptidase 25)	protein interactions	64386	12	1	19454	50	CLU
3.042e-02	-3.49	XK (X-linked Kx blood group antigen, Kell and VPS13A binding protein)	protein interactions	7504	12	1	19454	50	PRKCA
3.042e-02	-3.49	ART4 (ADP-ribosyltransferase 4 (inactive) (Dombrock blood group))	protein interactions	420	12	1	19454	50	GPM6A
3.042e-02	-3.49	PROK2 (prokineticin 2)	protein interactions	60675	12	1	19454	50	CPE
3.042e-02	-3.49	UGT1A9 (UDP glucuronosyltransferase family 1 member A9)	protein interactions	54600	12	1	19454	50	PON2
3.042e-02	-3.49	Ctnnbl1 (catenin, beta like 1)	protein interactions	66642	12	1	19454	50	PRKCA
3.042e-02	-3.49	NKX2-4 (NK2 homeobox 4)	protein interactions	644524	12	1	19454	50	NFIB
3.042e-02	-3.49	LMP-1 (latent membrane protein LMP-1)	protein interactions	3783750	12	1	19454	50	TNIK
3.042e-02	-3.49	NTF4 (neurotrophin 4)	protein interactions	4909	12	1	19454	50	NTRK2
3.042e-02	-3.49	CTF1 (cardiotrophin 1)	protein interactions	1489	12	1	19454	50	LIFR
3.042e-02	-3.49	BAMBI (BMP and activin membrane bound inhibitor)	protein interactions	25805	12	1	19454	50	BMPR1B
3.058e-02	-3.49	CTNNB1 (catenin beta 1)	protein interactions	1499	926	6	19454	50	NHSL1,PRKCA,PARD3B,PTPRZ1,DTNA,CTNND2
3.074e-02	-3.48	Carboxypeptidase-like, regulatory domain	gene3d domains	2.60.40.1120	11	1	14470	41	CPE
3.097e-02	-3.47	Signaling by the B Cell Receptor (BCR)	REACTOME pathways	R-HSA-983705	229	3	10285	31	ITPR2,FGFR3,NRG3
3.111e-02	-3.47	Post-translational modification: synthesis of GPI-anchored proteins	REACTOME pathways	R-HSA-163125	92	2	10285	31	NTM,LSAMP
3.126e-02	-3.47	transferase activity, transferring phosphorus-containing groups	molecular function	GO:0016772	903	6	18094	48	TNIK,BMPR1B,FGFR3,EFEMP1,NTRK2,PRKCA
3.138e-02	-3.46	inositol 1,4,5 trisphosphate binding	molecular function	GO:0070679	12	1	18094	48	ITPR2
3.138e-02	-3.46	adenylate cyclase binding	molecular function	GO:0008179	12	1	18094	48	ADCY2
3.147e-02	-3.46	EN1 (engrailed homeobox 1)	protein interactions	2019	108	2	19454	50	NFIB,NFIA
3.147e-02	-3.46	BIN1 (bridging integrator 1)	protein interactions	274	108	2	19454	50	GPM6A,CLU
3.147e-02	-3.46	PAX8 (paired box 8)	protein interactions	7849	108	2	19454	50	NFIB,NFIA
3.158e-02	-3.46	skin-neck-carcinoma-basal_cell_carcinoma	COSMIC cancer mutations	skin-neck-carcinoma-basal_cell_carcinoma	11	1	16828	49	FGFR3
3.158e-02	-3.46	pleomorphic_carcinoma	COSMIC cancer mutations	pleomorphic_carcinoma	11	1	16828	49	FGFR3
3.158e-02	-3.46	prostate-hyperplasia	COSMIC cancer mutations	prostate-hyperplasia	11	1	16828	49	FGFR3
3.158e-02	-3.46	skin-scalp-carcinoma-basal_cell_carcinoma	COSMIC cancer mutations	skin-scalp-carcinoma-basal_cell_carcinoma	11	1	16828	49	FGFR3
3.158e-02	-3.46	congenital	COSMIC cancer mutations	congenital	11	1	16828	49	FGFR3
3.158e-02	-3.46	skin-back-malignant_melanoma-superficial_spreading	COSMIC cancer mutations	skin-back-malignant_melanoma-superficial_spreading	11	1	16828	49	PREX2
3.158e-02	-3.46	skin-hand-malignant_melanoma-acral_lentiginous	COSMIC cancer mutations	skin-hand-malignant_melanoma-acral_lentiginous	11	1	16828	49	PREX2
3.158e-02	-3.46	kidney-other-oncocytoma	COSMIC cancer mutations	kidney-other-oncocytoma	11	1	16828	49	FGFR3
3.158e-02	-3.46	seborrhoeic_keratosis	COSMIC cancer mutations	seborrhoeic_keratosis	11	1	16828	49	FGFR3
3.158e-02	-3.46	oncocytoma	COSMIC cancer mutations	oncocytoma	11	1	16828	49	FGFR3
3.182e-02	-3.45	cell fate commitment	biological process	GO:0045165	257	3	18204	49	NFIA,NFIB,SOX5
3.184e-02	-3.45	nuclear membrane disassembly	biological process	GO:0051081	12	1	18204	49	PRKCA
3.184e-02	-3.45	sulfur amino acid transport	biological process	GO:0000101	12	1	18204	49	SLC1A2
3.184e-02	-3.45	mammalian oogenesis stage	biological process	GO:0022605	12	1	18204	49	BMPR1B
3.184e-02	-3.45	dicarboxylic acid biosynthetic process	biological process	GO:0043650	12	1	18204	49	GLUD1
3.184e-02	-3.45	regulation of glial cell apoptotic process	biological process	GO:0034350	12	1	18204	49	PRKCA
3.184e-02	-3.45	dermatan sulfate proteoglycan metabolic process	biological process	GO:0050655	12	1	18204	49	CSGALNACT1
3.184e-02	-3.45	positive regulation of extrinsic apoptotic signaling pathway via death domain receptors	biological process	GO:1902043	12	1	18204	49	BMPR1B
3.184e-02	-3.45	microglia differentiation	biological process	GO:0014004	12	1	18204	49	QKI
3.193e-02	-3.44	TGFB_receptor	interpro domains	IPR000333	12	1	18521	50	BMPR1B
3.197e-02	-3.44	Rap1 signaling pathway	KEGG pathways	ko04015	210	3	7161	24	PRKCA,FGFR3,ADCY2
3.197e-02	-3.44	Rap1 signaling pathway	KEGG pathways	hsa04015	210	3	7161	24	ADCY2,FGFR3,PRKCA
3.200e-02	-3.44	CLSTN1 (calsyntenin 1)	protein interactions	22883	109	2	19454	50	SLC1A3,MGAT4C
3.200e-02	-3.44	ZNRF4 (zinc and ring finger 4)	protein interactions	148066	109	2	19454	50	PON2,ITPR2
3.200e-02	-3.44	MIR34B (microRNA 34b)	protein interactions	407041	109	2	19454	50	QKI,MSI2
3.204e-02	-3.44	human chr9q21.33	chromosome location	human chr9q21.33	17	1	26134	50	NTRK2
3.207e-02	-3.44	biliary_tract-bile_duct-carcinoma-adenocarcinoma	COSMIC cancer mutations	biliary_tract-bile_duct-carcinoma-adenocarcinoma	15095	48	16828	49	NPAS3,NFIA,ITPR2,QKI,PRKCA,GLIS3,MACF1,SOX5,MGAT4C,NTRK2,SLC1A3,NRXN1,NFIB,SLC1A2,CDH20,LSAMP,EFEMP1,RORA,GLUD1,BMPR1B,ATP13A4,PITPNC1,PARD3B,MSI2,TNIK,LIFR,DTNA,NRG3,PON2,FGFR3,ATP1A2,AQP4,GPM6A,NHSL1,PTPRZ1,CPE,RBMS3,CLU,FBXL7,NTM,ADCY2,CSGALNACT1,PREX2,CTNND2,SFXN5,ZBTB20,FMN2,PCDH9
3.207e-02	-3.44	bile_duct	COSMIC cancer mutations	bile_duct	15095	48	16828	49	TNIK,LIFR,PARD3B,MSI2,BMPR1B,ATP13A4,PITPNC1,GLUD1,RORA,EFEMP1,LSAMP,CDH20,NFIB,SLC1A2,MGAT4C,NRXN1,NTRK2,SLC1A3,SOX5,PRKCA,GLIS3,MACF1,QKI,NPAS3,NFIA,ITPR2,FMN2,PCDH9,ZBTB20,PREX2,CTNND2,SFXN5,CSGALNACT1,ADCY2,FBXL7,CLU,NTM,RBMS3,CPE,PTPRZ1,NHSL1,FGFR3,AQP4,GPM6A,ATP1A2,NRG3,PON2,DTNA
3.224e-02	-3.43	response to chemical	biological process	GO:0042221	3743	16	18204	49	LIFR,PRKCA,TNIK,CLU,FMN2,NTRK2,ATP1A2,SLC1A2,RORA,PON2,AQP4,ADCY2,ITPR2,NRG3,SLC1A3,ZBTB20
3.237e-02	-3.43	Negative regulation of the PI3K/AKT network	REACTOME pathways	R-HSA-199418	94	2	10285	31	FGFR3,NRG3
3.245e-02	-3.43	ErbB signaling pathway	KEGG pathways	ko04012	85	2	7161	24	NRG3,PRKCA
3.245e-02	-3.43	ErbB signaling pathway	KEGG pathways	hsa04012	85	2	7161	24	PRKCA,NRG3
3.251e-02	-3.43	gland morphogenesis	biological process	GO:0022612	105	2	18204	49	NRG3,NFIB
3.251e-02	-3.43	cellular response to alcohol	biological process	GO:0097306	105	2	18204	49	ITPR2,ADCY2
3.251e-02	-3.43	response to interleukin-1	biological process	GO:0070555	105	2	18204	49	PRKCA,RORA
3.254e-02	-3.43	LZTR1 (leucine zipper like post translational regulator 1)	protein interactions	8216	110	2	19454	50	PARD3B,BMPR1B
3.256e-02	-3.42	SNCA (synuclein alpha)	protein interactions	6622	696	5	19454	50	NTRK2,CLU,GPM6A,TNIK,MACF1
3.256e-02	-3.42	CarboxypepD_reg	pfam domains	PF13620	12	1	17795	49	CPE
3.264e-02	-3.42	functioning	COSMIC cancer mutations	functioning	1803	10	16828	49	SLC1A2,NHSL1,NTRK2,ZBTB20,FMN2,PCDH9,EFEMP1,PTPRZ1,NRG3,SOX5
3.264e-02	-3.42	adrenal_gland-adrenal_gland-adrenal_cortical_carcinoma-functioning	COSMIC cancer mutations	adrenal_gland-adrenal_gland-adrenal_cortical_carcinoma-functioning	1803	10	16828	49	NTRK2,SLC1A2,NHSL1,SOX5,NRG3,PTPRZ1,ZBTB20,FMN2,EFEMP1,PCDH9
3.269e-02	-3.42	Phase I biotransformations, non P450	WikiPathways	WP136	8	1	5310	22	PON2
3.276e-02	-3.42	steroid binding	molecular function	GO:0005496	107	2	18094	48	ATP1A2,RORA
3.281e-02	-3.42	distal axon	cellular component	GO:0150034	273	3	19108	49	PCDH9,NTRK2,GPM6A
3.291e-02	-3.41	PCDHA2 (protocadherin alpha 2)	protein interactions	56146	13	1	19454	50	NFIA
3.291e-02	-3.41	TBCC (tubulin folding cofactor C)	protein interactions	6903	13	1	19454	50	NTM
3.291e-02	-3.41	MYO16 (myosin XVI)	protein interactions	23026	13	1	19454	50	NRXN1
3.291e-02	-3.41	Rbm47 (RNA binding motif protein 47)	protein interactions	245945	13	1	19454	50	QKI
3.291e-02	-3.41	IL23R (interleukin 23 receptor)	protein interactions	149233	13	1	19454	50	PRKCA
3.291e-02	-3.41	SPINK5 (serine peptidase inhibitor Kazal type 5)	protein interactions	11005	13	1	19454	50	CSGALNACT1
3.291e-02	-3.41	ST3GAL5 (ST3 beta-galactoside alpha-2,3-sialyltransferase 5)	protein interactions	8869	13	1	19454	50	PON2
3.291e-02	-3.41	DDIAS (DNA damage induced apoptosis suppressor)	protein interactions	220042	13	1	19454	50	EFEMP1
3.291e-02	-3.41	RAB3C (RAB3C, member RAS oncogene family)	protein interactions	115827	13	1	19454	50	GPM6A
3.291e-02	-3.41	KCNQ2 (potassium voltage-gated channel subfamily Q member 2)	protein interactions	3785	13	1	19454	50	PRKCA
3.300e-02	-3.41	dermatan sulfate biosynthesis	BIOCYC pathways	META_PWY-6571	15	1	902	2	CSGALNACT1
3.307e-02	-3.41	oogenesis	biological process	GO:0048477	106	2	18204	49	FMN2,BMPR1B
3.309e-02	-3.41	HYPK (huntingtin interacting protein K)	protein interactions	25764	111	2	19454	50	QKI,GLUD1
3.309e-02	-3.41	BCL7C (BAF chromatin remodeling complex subunit BCL7C)	protein interactions	9274	111	2	19454	50	NFIA,NFIB
3.332e-02	-3.40	tube development	biological process	GO:0035295	903	6	18204	49	NFIA,PRKCA,QKI,NFIB,NTRK2,RORA
3.368e-02	-3.39	large_intestine-rectum-adenoma	COSMIC cancer mutations	large_intestine-rectum-adenoma	99	2	16828	49	LIFR,NTRK2
3.389e-02	-3.38	human chr18q21.33	chromosome location	human chr18q21.33	18	1	26134	50	CDH20
3.389e-02	-3.38	human chr7q31.32	chromosome location	human chr7q31.32	18	1	26134	50	PTPRZ1
3.395e-02	-3.38	MIR	prosite domains	PS50919	10	1	12186	42	ITPR2
3.395e-02	-3.38	MIP	prosite domains	PS00221	10	1	12186	42	AQP4
3.395e-02	-3.38	potassium ion binding	molecular function	GO:0030955	13	1	18094	48	ATP1A2
3.395e-02	-3.38	transforming growth factor beta receptor activity	molecular function	GO:0005024	13	1	18094	48	BMPR1B
3.400e-02	-3.38	calcium ion binding	molecular function	GO:0005509	683	5	18094	48	PCDH9,NRXN1,ITPR2,EFEMP1,MACF1
3.408e-02	-3.38	organic anion transmembrane transporter activity	molecular function	GO:0008514	268	3	18094	48	SLC1A3,SLC1A2,SFXN5
3.418e-02	-3.38	GFI1B (growth factor independent 1B transcriptional repressor)	protein interactions	8328	113	2	19454	50	EFEMP1,DTNA
3.425e-02	-3.37	ACIN1 (apoptotic chromatin condensation inducer 1)	protein interactions	22985	277	3	19454	50	NFIA,PRKCA,CSGALNACT1
3.439e-02	-3.37	ear	COSMIC cancer mutations	ear	624	5	16828	49	NPAS3,MGAT4C,LIFR,ZBTB20,FGFR3
3.440e-02	-3.37	cervix-carcinoma-mixed_adenosquamous_carcinoma	COSMIC cancer mutations	cervix-carcinoma-mixed_adenosquamous_carcinoma	12	1	16828	49	FGFR3
3.440e-02	-3.37	skin-abdomen-malignant_melanoma-nodular	COSMIC cancer mutations	skin-abdomen-malignant_melanoma-nodular	12	1	16828	49	PREX2
3.440e-02	-3.37	central_nervous_system-fourth_ventricle-glioma-astrocytoma_Grade_I	COSMIC cancer mutations	central_nervous_system-fourth_ventricle-glioma-astrocytoma_Grade_I	12	1	16828	49	QKI
3.440e-02	-3.37	skin-face-carcinoma-basal_cell_carcinoma	COSMIC cancer mutations	skin-face-carcinoma-basal_cell_carcinoma	12	1	16828	49	FGFR3
3.440e-02	-3.37	skin-benign_melanocytic_nevus	COSMIC cancer mutations	skin-benign_melanocytic_nevus	12	1	16828	49	FGFR3
3.444e-02	-3.37	membrane disassembly	biological process	GO:0030397	13	1	18204	49	PRKCA
3.444e-02	-3.37	postsynaptic specialization assembly	biological process	GO:0098698	13	1	18204	49	NRXN1
3.444e-02	-3.37	commissural neuron axon guidance	biological process	GO:0071679	13	1	18204	49	NFIB
3.444e-02	-3.37	ectodermal placode development	biological process	GO:0071696	13	1	18204	49	NRG3
3.444e-02	-3.37	T-helper 17 cell differentiation	biological process	GO:0072539	13	1	18204	49	RORA
3.444e-02	-3.37	negative regulation of amyloid fibril formation	biological process	GO:1905907	13	1	18204	49	CLU
3.444e-02	-3.37	cerebellar Purkinje cell differentiation	biological process	GO:0021702	13	1	18204	49	RORA
3.444e-02	-3.37	defense response to tumor cell	biological process	GO:0002357	13	1	18204	49	RBMS3
3.444e-02	-3.37	regulation of respiratory gaseous exchange by nervous system process	biological process	GO:0002087	13	1	18204	49	ATP1A2
3.444e-02	-3.37	negative regulation of cytosolic calcium ion concentration	biological process	GO:0051481	13	1	18204	49	ATP1A2
3.459e-02	-3.36	GABAergic synapse	KEGG pathways	hsa04727	88	2	7161	24	ADCY2,PRKCA
3.459e-02	-3.36	GABAergic synapse	KEGG pathways	ko04727	88	2	7161	24	ADCY2,PRKCA
3.462e-02	-3.36	Intracellular Signalling Through Prostacyclin Receptor and Prostacyclin	SMPDB pathways	SMP0000354	8	1	1369	6	ADCY2
3.462e-02	-3.36	Glucose-Alanine Cycle	SMPDB pathways	SMP0000127	8	1	1369	6	GLUD1
3.462e-02	-3.36	Bile Acid Indirect Signalling Pathway	SMPDB pathways	SMP0086851	8	1	1369	6	FGFR3
3.474e-02	-3.36	PTP4A2 (protein tyrosine phosphatase 4A2)	protein interactions	8073	114	2	19454	50	PON2,FMN2
3.481e-02	-3.36	postsynapse organization	biological process	GO:0099173	109	2	18204	49	NRXN1,CTNND2
3.481e-02	-3.36	positive regulation of tumor necrosis factor production	biological process	GO:0032760	109	2	18204	49	CLU,ZBTB20
3.500e-02	-3.35	Cadherin_CS	interpro domains	IPR020894	109	2	18521	50	CDH20,PCDH9
3.506e-02	-3.35	chemical homeostasis	biological process	GO:0048878	914	6	18204	49	ATP13A4,AQP4,ZBTB20,RORA,ATP1A2,SLC1A3
3.518e-02	-3.35	chondroitin sulfate biosynthesis	BIOCYC pathways	HUMAN_PWY-6569	16	1	902	2	CSGALNACT1
3.527e-02	-3.34	ACTB (actin beta)	protein interactions	60	958	6	19454	50	MACF1,PRKCA,SFXN5,NHSL1,FMN2,DTNA
3.530e-02	-3.34	HMG20B (high mobility group 20B)	protein interactions	10362	115	2	19454	50	SOX5,NFIB
3.530e-02	-3.34	TBXT (T-box transcription factor T)	protein interactions	6862	115	2	19454	50	NFIB,NFIA
3.530e-02	-3.34	SMAD7 (SMAD family member 7)	protein interactions	4092	115	2	19454	50	BMPR1B,SOX5
3.532e-02	-3.34	chromaffin granule	cellular component	GO:0042583	14	1	19108	49	CLU
3.537e-02	-3.34	protein localization to membrane	biological process	GO:0072657	462	4	18204	49	TNIK,MACF1,CPE,NRXN1
3.539e-02	-3.34	positive regulation of cell junction assembly	biological process	GO:1901890	110	2	18204	49	NTRK2,NRXN1
3.540e-02	-3.34	SYT5 (synaptotagmin 5)	protein interactions	6861	14	1	19454	50	NRXN1
3.540e-02	-3.34	CHAT (choline O-acetyltransferase)	protein interactions	1103	14	1	19454	50	PRKCA
3.540e-02	-3.34	TAS2R7 (taste 2 receptor member 7)	protein interactions	50837	14	1	19454	50	PRKCA
3.540e-02	-3.34	ZNF628 (zinc finger protein 628)	protein interactions	89887	14	1	19454	50	EFEMP1
3.540e-02	-3.34	Aifm1 (apoptosis-inducing factor, mitochondrion-associated 1)	protein interactions	26926	14	1	19454	50	CLU
3.540e-02	-3.34	SLC1A2 (solute carrier family 1 member 2)	protein interactions	6506	14	1	19454	50	SLC1A2
3.540e-02	-3.34	BOD1L2 (biorientation of chromosomes in cell division 1 like 2)	protein interactions	284257	14	1	19454	50	FMN2
3.540e-02	-3.34	FGF7 (fibroblast growth factor 7)	protein interactions	2252	14	1	19454	50	FGFR3
3.540e-02	-3.34	C9 (complement C9)	protein interactions	735	14	1	19454	50	CLU
3.540e-02	-3.34	DACT2 (dishevelled binding antagonist of beta catenin 2)	protein interactions	168002	14	1	19454	50	ZBTB20
3.540e-02	-3.34	Stag2 (STAG2 cohesin complex component)	protein interactions	20843	14	1	19454	50	CLU
3.540e-02	-3.34	RHEBL1 (RHEB like 1)	protein interactions	121268	14	1	19454	50	BMPR1B
3.540e-02	-3.34	Asap1 (ArfGAP with SH3 domain, ankyrin repeat and PH domain1)	protein interactions	13196	14	1	19454	50	MACF1
3.540e-02	-3.34	Nedd4 (neural precursor cell expressed, developmentally down-regulated 4)	protein interactions	17999	14	1	19454	50	GLIS3
3.559e-02	-3.34	side of membrane	cellular component	GO:0098552	715	5	19108	49	NTM,LIFR,LSAMP,DTNA,AQP4
3.559e-02	-3.34	FGFR3 mutant receptor activation	REACTOME pathways	R-HSA-2033514	12	1	10285	31	FGFR3
3.559e-02	-3.34	Signaling by activated point mutants of FGFR3	REACTOME pathways	R-HSA-1839130	12	1	10285	31	FGFR3
3.574e-02	-3.33	human chr11q25	chromosome location	human chr11q25	19	1	26134	50	NTM
3.574e-02	-3.33	human chr6q24.1	chromosome location	human chr6q24.1	19	1	26134	50	NHSL1
3.574e-02	-3.33	human chr5p15.2	chromosome location	human chr5p15.2	19	1	26134	50	CTNND2
3.574e-02	-3.33	human chr10q23.2	chromosome location	human chr10q23.2	19	1	26134	50	GLUD1
3.586e-02	-3.33	RDH11 (retinol dehydrogenase 11)	protein interactions	51109	116	2	19454	50	PRKCA,PON2
3.604e-02	-3.32	rhythmic process	biological process	GO:0048511	270	3	18204	49	RORA,NTRK2,BMPR1B
3.631e-02	-3.32	tube morphogenesis	biological process	GO:0035239	685	5	18204	49	NTRK2,PRKCA,RORA,QKI,NFIB
3.633e-02	-3.32	env (Envelope surface glycoprotein gp160, precursor)	protein interactions	155971	1501	8	19454	50	NTRK2,PON2,ADCY2,PRKCA,MGAT4C,SLC1A2,EFEMP1,BMPR1B
3.638e-02	-3.31	carboxylic acid biosynthetic process	biological process	GO:0046394	271	3	18204	49	GLUD1,SLC1A3,QKI
3.642e-02	-3.31	ELK3 (ETS transcription factor ELK3)	protein interactions	2004	117	2	19454	50	NFIB,NFIA
3.646e-02	-3.31	skin-scalp-malignant_melanoma	COSMIC cancer mutations	skin-scalp-malignant_melanoma	634	5	16828	49	FMN2,NFIA,NTM,PTPRZ1,PREX2
3.647e-02	-3.31	FOS (Fos proto-oncogene, AP-1 transcription factor subunit)	protein interactions	2353	284	3	19454	50	NFIA,NFIB,CLU
3.652e-02	-3.31	microtubule minus-end binding	molecular function	GO:0051011	14	1	18094	48	MACF1
3.657e-02	-3.31	regulation of gliogenesis	biological process	GO:0014013	112	2	18204	49	PTPRZ1,QKI
3.668e-02	-3.31	CAV1 (caveolin 1)	protein interactions	857	719	5	19454	50	DTNA,MACF1,FMN2,TNIK,SLC1A3
3.670e-02	-3.31	phosphatidylinositol binding	molecular function	GO:0035091	276	3	18094	48	ITPR2,PARD3B,PITPNC1
3.678e-02	-3.30	Morphine addiction	KEGG pathways	ko05032	91	2	7161	24	ADCY2,PRKCA
3.678e-02	-3.30	Morphine addiction	KEGG pathways	hsa05032	91	2	7161	24	ADCY2,PRKCA
3.680e-02	-3.30	P4HA1 (prolyl 4-hydroxylase subunit alpha 1)	protein interactions	5033	285	3	19454	50	EFEMP1,PON2,DTNA
3.699e-02	-3.30	ARID3A (AT-rich interaction domain 3A)	protein interactions	1820	118	2	19454	50	NFIB,NFIA
3.699e-02	-3.30	DNM1 (dynamin 1)	protein interactions	1759	118	2	19454	50	PRKCA,GPM6A
3.699e-02	-3.30	CEACAM8 (CEA cell adhesion molecule 8)	protein interactions	1088	118	2	19454	50	CPE,CLU
3.702e-02	-3.30	arm	COSMIC cancer mutations	arm	1331	8	16828	49	NPAS3,PRKCA,NTM,MACF1,FGFR3,ATP1A2,PARD3B,ZBTB20
3.704e-02	-3.30	response to forskolin	biological process	GO:1904321	14	1	18204	49	ADCY2
3.704e-02	-3.30	negative regulation of sodium ion transmembrane transporter activity	biological process	GO:2000650	14	1	18204	49	ATP1A2
3.704e-02	-3.30	cellular response to forskolin	biological process	GO:1904322	14	1	18204	49	ADCY2
3.704e-02	-3.30	cellular response to ethanol	biological process	GO:0071361	14	1	18204	49	ITPR2
3.704e-02	-3.30	relaxation of cardiac muscle	biological process	GO:0055119	14	1	18204	49	ATP1A2
3.704e-02	-3.30	cerebrospinal fluid circulation	biological process	GO:0090660	14	1	18204	49	AQP4
3.704e-02	-3.30	sodium ion export across plasma membrane	biological process	GO:0036376	14	1	18204	49	ATP1A2
3.704e-02	-3.30	glutathione biosynthetic process	biological process	GO:0006750	14	1	18204	49	SLC1A2
3.706e-02	-3.30	vascular process in circulatory system	biological process	GO:0003018	273	3	18204	49	ATP1A2,SLC1A2,SLC1A3
3.709e-02	-3.29	cellular homeostasis	biological process	GO:0019725	689	5	18204	49	ATP13A4,SLC1A3,ATP1A2,AQP4,ZBTB20
3.715e-02	-3.29	MIP	interpro domains	IPR000425	14	1	18521	50	AQP4
3.715e-02	-3.29	Neurexin-like	interpro domains	IPR003585	14	1	18521	50	NRXN1
3.715e-02	-3.29	Aquaporin-like	interpro domains	IPR023271	14	1	18521	50	AQP4
3.717e-02	-3.29	dendrite development	biological process	GO:0016358	113	2	18204	49	CTNND2,PREX2
3.717e-02	-3.29	positive regulation of tumor necrosis factor superfamily cytokine production	biological process	GO:1903557	113	2	18204	49	CLU,ZBTB20
3.721e-02	-3.29	central_nervous_system-hypothalamus-glioma-astrocytoma_Grade_I	COSMIC cancer mutations	central_nervous_system-hypothalamus-glioma-astrocytoma_Grade_I	13	1	16828	49	QKI
3.721e-02	-3.29	cervix-carcinoma-adenocarcinoma	COSMIC cancer mutations	cervix-carcinoma-adenocarcinoma	13	1	16828	49	FGFR3
3.721e-02	-3.29	skin-shoulder-malignant_melanoma-nodular	COSMIC cancer mutations	skin-shoulder-malignant_melanoma-nodular	13	1	16828	49	PREX2
3.721e-02	-3.29	skin-back-carcinoma-basal_cell_carcinoma	COSMIC cancer mutations	skin-back-carcinoma-basal_cell_carcinoma	13	1	16828	49	FGFR3
3.721e-02	-3.29	Brenner_tumour	COSMIC cancer mutations	Brenner_tumour	13	1	16828	49	FGFR3
3.721e-02	-3.29	skin-scalp-malignant_melanoma-nodular	COSMIC cancer mutations	skin-scalp-malignant_melanoma-nodular	13	1	16828	49	PREX2
3.721e-02	-3.29	endometrium-ovary-endometriosis	COSMIC cancer mutations	endometrium-ovary-endometriosis	13	1	16828	49	FGFR3
3.728e-02	-3.29	RECEPTOR_TYR_KIN_II	prosite domains	PS00239	11	1	12186	42	NTRK2
3.740e-02	-3.29	organic acid biosynthetic process	biological process	GO:0016053	274	3	18204	49	QKI,SLC1A3,GLUD1
3.745e-02	-3.28	PARD3 (par-3 family cell polarity regulator)	protein interactions	56288	287	3	19454	50	DTNA,NTRK2,PARD3B
3.745e-02	-3.28	DHFR2 (dihydrofolate reductase 2)	protein interactions	200895	287	3	19454	50	SLC1A3,ITPR2,CPE
3.750e-02	-3.28	central_nervous_system-cerebellum-glioma-astrocytoma_Grade_I	COSMIC cancer mutations	central_nervous_system-cerebellum-glioma-astrocytoma_Grade_I	105	2	16828	49	QKI,NRG3
3.754e-02	-3.28	cellular response to organic substance	biological process	GO:0071310	1716	9	18204	49	ZBTB20,SLC1A2,ATP1A2,SLC1A3,RORA,ITPR2,AQP4,ADCY2,LIFR
3.756e-02	-3.28	HLA-DPA1 (major histocompatibility complex, class II, DP alpha 1)	protein interactions	3113	119	2	19454	50	PCDH9,CLU
3.759e-02	-3.28	human chr8p21.1	chromosome location	human chr8p21.1	20	1	26134	50	CLU
3.780e-02	-3.28	axolemma	cellular component	GO:0030673	15	1	19108	49	SLC1A2
3.788e-02	-3.27	OGG1 (8-oxoguanine DNA glycosylase)	protein interactions	4968	15	1	19454	50	PRKCA
3.788e-02	-3.27	FN3K (fructosamine 3 kinase)	protein interactions	64122	15	1	19454	50	PRKCA
3.788e-02	-3.27	ENTPD5 (ectonucleoside triphosphate diphosphohydrolase 5 (inactive))	protein interactions	957	15	1	19454	50	PRKCA
3.788e-02	-3.27	TESPA1 (thymocyte expressed, positive selection associated 1)	protein interactions	9840	15	1	19454	50	ITPR2
3.788e-02	-3.27	ADRA1B (adrenoceptor alpha 1B)	protein interactions	147	15	1	19454	50	PRKCA
3.788e-02	-3.27	PCSK1N (proprotein convertase subtilisin/kexin type 1 inhibitor)	protein interactions	27344	15	1	19454	50	MGAT4C
3.788e-02	-3.27	TIAM2 (TIAM Rac1 associated GEF 2)	protein interactions	26230	15	1	19454	50	TNIK
3.788e-02	-3.27	Cry1 (cryptochrome circadian regulator 1)	protein interactions	12952	15	1	19454	50	NFIB
3.788e-02	-3.27	IGSF1 (immunoglobulin superfamily member 1)	protein interactions	3547	15	1	19454	50	BMPR1B
3.788e-02	-3.27	FGF9 (fibroblast growth factor 9)	protein interactions	2254	15	1	19454	50	FGFR3
3.788e-02	-3.27	GRM7 (glutamate metabotropic receptor 7)	protein interactions	2917	15	1	19454	50	PRKCA
3.788e-02	-3.27	MIP	pfam domains	PF00230	14	1	17795	49	AQP4
3.798e-02	-3.27	Cadherin-like_dom	interpro domains	IPR002126	114	2	18521	50	CDH20,PCDH9
3.806e-02	-3.27	positive regulation of MAPK cascade	biological process	GO:0043410	473	4	18204	49	FGFR3,PRKCA,TNIK,NTRK2
3.811e-02	-3.27	Cadherin	pfam domains	PF00028	112	2	17795	49	PCDH9,CDH20
3.819e-02	-3.27	membrane raft	cellular component	GO:0045121	290	3	19108	49	ADCY2,SLC1A2,ATP1A2
3.822e-02	-3.26	oesophagus-middle_third-carcinoma-squamous_cell_carcinoma	COSMIC cancer mutations	oesophagus-middle_third-carcinoma-squamous_cell_carcinoma	3531	16	16828	49	NHSL1,ZBTB20,FMN2,TNIK,PCDH9,PTPRZ1,CTNND2,PREX2,SOX5,NFIB,ATP1A2,GPM6A,ADCY2,PON2,MACF1,NRG3
3.840e-02	-3.26	middle_third	COSMIC cancer mutations	middle_third	3533	16	16828	49	CTNND2,PREX2,SOX5,PTPRZ1,ZBTB20,PCDH9,TNIK,FMN2,NHSL1,NRG3,PON2,MACF1,ADCY2,ATP1A2,GPM6A,NFIB
3.843e-02	-3.26	BCOR (BCL6 corepressor)	protein interactions	54880	290	3	19454	50	SOX5,NFIB,NFIA
3.844e-02	-3.26	MIR	smart domains	SM00472	10	1	9717	38	ITPR2
3.850e-02	-3.26	ERBB2 Activates PTK6 Signaling	REACTOME pathways	R-HSA-8847993	13	1	10285	31	NRG3
3.850e-02	-3.26	CLEC7A (Dectin-1) induces NFAT activation	REACTOME pathways	R-HSA-5607763	13	1	10285	31	ITPR2
3.850e-02	-3.26	Passive transport by Aquaporins	REACTOME pathways	R-HSA-432047	13	1	10285	31	AQP4
3.850e-02	-3.26	FGFR3 ligand binding and activation	REACTOME pathways	R-HSA-190239	13	1	10285	31	FGFR3
3.850e-02	-3.26	Phospholipase C-mediated cascade; FGFR3	REACTOME pathways	R-HSA-5654227	13	1	10285	31	FGFR3
3.850e-02	-3.26	FGFR3c ligand binding and activation	REACTOME pathways	R-HSA-190372	13	1	10285	31	FGFR3
3.855e-02	-3.26	calcium channel activity	molecular function	GO:0005262	117	2	18094	48	ITPR2,GPM6A
3.855e-02	-3.26	solute:monoatomic cation symporter activity	molecular function	GO:0015294	117	2	18094	48	SLC1A3,SLC1A2
3.860e-02	-3.25	molecular transducer activity	molecular function	GO:0060089	1474	8	18094	48	BMPR1B,FGFR3,NRXN1,PTPRZ1,NTRK2,EFEMP1,RORA,LIFR
3.860e-02	-3.25	signaling receptor activity	molecular function	GO:0038023	1474	8	18094	48	LIFR,NTRK2,PTPRZ1,EFEMP1,RORA,NRXN1,BMPR1B,FGFR3
3.872e-02	-3.25	MED15 (mediator complex subunit 15)	protein interactions	51586	121	2	19454	50	NFIA,QKI
3.885e-02	-3.25	membrane microdomain	cellular component	GO:0098857	292	3	19108	49	ADCY2,SLC1A2,ATP1A2
3.887e-02	-3.25	TyrKc	smart domains	SM00219	80	2	9717	38	NTRK2,FGFR3
3.887e-02	-3.25	Excitatory Neural Signalling Through 5-HTR 4 and Serotonin	SMPDB pathways	SMP0000309	9	1	1369	6	ADCY2
3.887e-02	-3.25	Intracellular Signalling Through FSH Receptor and Follicle Stimulating Hormone	SMPDB pathways	SMP0000333	9	1	1369	6	ADCY2
3.887e-02	-3.25	Excitatory Neural Signalling Through 5-HTR 6 and Serotonin	SMPDB pathways	SMP0000312	9	1	1369	6	ADCY2
3.887e-02	-3.25	Excitatory Neural Signalling Through 5-HTR 7 and Serotonin	SMPDB pathways	SMP0000311	9	1	1369	6	ADCY2
3.887e-02	-3.25	Intracellular Signalling Through Histamine H2 Receptor and Histamine	SMPDB pathways	SMP0000335	9	1	1369	6	ADCY2
3.887e-02	-3.25	Nitric Oxide Signaling Pathway	SMPDB pathways	SMP0063777	9	1	1369	6	PRKCA
3.894e-02	-3.25	localization	biological process	GO:0051179	4474	18	18204	49	NTRK2,FMN2,CLU,TNIK,ATP13A4,PARD3B,QKI,PITPNC1,ATP1A2,SFXN5,SLC1A2,ITPR2,MACF1,AQP4,NRXN1,SLC1A3,GPM6A,CPE
3.896e-02	-3.25	Glycerol uptake facilitator protein	gene3d domains	1.20.1080.10	14	1	14470	41	AQP4
3.908e-02	-3.24	neurexin family protein binding	molecular function	GO:0042043	15	1	18094	48	CPE
3.908e-02	-3.24	phosphatidylglycerol binding	molecular function	GO:1901611	15	1	18094	48	PITPNC1
3.914e-02	-3.24	skin-leg-malignant_melanoma-nodular	COSMIC cancer mutations	skin-leg-malignant_melanoma-nodular	258	3	16828	49	PTPRZ1,FMN2,ATP13A4
3.920e-02	-3.24	Cadherin-like_sf	interpro domains	IPR015919	116	2	18521	50	CDH20,PCDH9
3.930e-02	-3.24	BRK1 (BRICK1 subunit of SCAR/WAVE actin nucleating complex)	protein interactions	55845	122	2	19454	50	NHSL1,DTNA
3.930e-02	-3.24	MED31 (mediator complex subunit 31)	protein interactions	51003	122	2	19454	50	QKI,CPE
3.935e-02	-3.24	perinuclear region of cytoplasm	cellular component	GO:0048471	735	5	19108	49	FMN2,SLC1A3,PRKCA,CLU,NTRK2
3.943e-02	-3.23	human chr10q23.1	chromosome location	human chr10q23.1	21	1	26134	50	NRG3
3.943e-02	-3.23	human chr4q32.3	chromosome location	human chr4q32.3	21	1	26134	50	CPE
3.948e-02	-3.23	glycoprotein biosynthetic process	biological process	GO:0009101	280	3	18204	49	CSGALNACT1,BMPR1B,MGAT4C
3.953e-02	-3.23	chondroitin sulfate biosynthesis	BIOCYC pathways	META_PWY-6569	18	1	902	2	CSGALNACT1
3.959e-02	-3.23	regulation of synapse assembly	biological process	GO:0051963	117	2	18204	49	NTRK2,NRXN1
3.964e-02	-3.23	synapse maturation	biological process	GO:0060074	15	1	18204	49	NFIA
3.964e-02	-3.23	peripheral nervous system neuron development	biological process	GO:0048935	15	1	18204	49	NTRK2
3.964e-02	-3.23	intracellular potassium ion homeostasis	biological process	GO:0030007	15	1	18204	49	ATP1A2
3.964e-02	-3.23	neuroblast division	biological process	GO:0055057	15	1	18204	49	SOX5
3.964e-02	-3.23	cerebellar Purkinje cell layer formation	biological process	GO:0021694	15	1	18204	49	RORA
3.964e-02	-3.23	regulation of neuron projection arborization	biological process	GO:0150011	15	1	18204	49	MACF1
3.964e-02	-3.23	peripheral nervous system neuron differentiation	biological process	GO:0048934	15	1	18204	49	NTRK2
3.964e-02	-3.23	chondrocyte proliferation	biological process	GO:0035988	15	1	18204	49	FGFR3
3.964e-02	-3.23	protein homotrimerization	biological process	GO:0070207	15	1	18204	49	SLC1A2
3.964e-02	-3.23	negative regulation of sodium ion transmembrane transport	biological process	GO:1902306	15	1	18204	49	ATP1A2
3.967e-02	-3.23	skin-head_neck-carcinoma-squamous_cell_carcinoma	COSMIC cancer mutations	skin-head_neck-carcinoma-squamous_cell_carcinoma	14191	46	16828	49	RORA,EFEMP1,LSAMP,CDH20,SLC1A2,MGAT4C,NRXN1,SLC1A3,NTRK2,LIFR,TNIK,PARD3B,ATP13A4,BMPR1B,PITPNC1,GLUD1,PRKCA,MACF1,GLIS3,QKI,NPAS3,ITPR2,NFIA,SOX5,ADCY2,FBXL7,CLU,NTM,FMN2,PCDH9,ZBTB20,PREX2,CTNND2,SFXN5,CSGALNACT1,FGFR3,AQP4,GPM6A,ATP1A2,NRG3,PON2,DTNA,CPE,PTPRZ1,NHSL1,NKAIN3
3.975e-02	-3.23	FH2_Formin	interpro domains	IPR015425	15	1	18521	50	FMN2
3.975e-02	-3.23	ATPase_P-typ_cation-transptr_C	interpro domains	IPR006068	15	1	18521	50	ATP1A2
3.975e-02	-3.23	CNH_dom	interpro domains	IPR001180	15	1	18521	50	TNIK
3.975e-02	-3.23	FH2_Formin_sf	interpro domains	IPR042201	15	1	18521	50	FMN2
3.988e-02	-3.22	PAX7 (paired box 7)	protein interactions	5081	123	2	19454	50	NFIA,NFIB
4.002e-02	-3.22	in_situ_neoplasm	COSMIC cancer mutations	in_situ_neoplasm	14	1	16828	49	FGFR3
4.002e-02	-3.22	small_round_cell_tumour	COSMIC cancer mutations	small_round_cell_tumour	14	1	16828	49	FGFR3
4.002e-02	-3.22	endometriosis	COSMIC cancer mutations	endometriosis	14	1	16828	49	FGFR3
4.002e-02	-3.22	urinary_tract-renal_pelvis-carcinoma-transitional_cell_carcinoma	COSMIC cancer mutations	urinary_tract-renal_pelvis-carcinoma-transitional_cell_carcinoma	14	1	16828	49	FGFR3
4.002e-02	-3.22	soft_tissue-small_round_cell_tumour	COSMIC cancer mutations	soft_tissue-small_round_cell_tumour	14	1	16828	49	FGFR3
4.015e-02	-3.22	rhabdomyosarcoma	COSMIC cancer mutations	rhabdomyosarcoma	4150	18	16828	49	NHSL1,PARD3B,FMN2,PREX2,CTNND2,PTPRZ1,NPAS3,SLC1A3,NFIA,ADCY2,FGFR3,RORA,AQP4,CLU,PON2,MACF1,CDH20,GLIS3
4.027e-02	-3.21	postsynaptic density, intracellular component	cellular component	GO:0099092	16	1	19108	49	TNIK
4.035e-02	-3.21	HLA-H (major histocompatibility complex, class I, H (pseudogene))	protein interactions	3136	16	1	19454	50	FGFR3
4.035e-02	-3.21	WWC3 (WWC family member 3)	protein interactions	55841	16	1	19454	50	PRKCA
4.035e-02	-3.21	CTSK (cathepsin K)	protein interactions	1513	16	1	19454	50	FGFR3
4.035e-02	-3.21	SYT4 (synaptotagmin 4)	protein interactions	6860	16	1	19454	50	NRXN1
4.035e-02	-3.21	SYT9 (synaptotagmin 9)	protein interactions	143425	16	1	19454	50	NRXN1
4.035e-02	-3.21	RHO (rhodopsin)	protein interactions	6010	16	1	19454	50	PRKCA
4.035e-02	-3.21	CNTFR (ciliary neurotrophic factor receptor)	protein interactions	1271	16	1	19454	50	LIFR
4.035e-02	-3.21	SLC6A9 (solute carrier family 6 member 9)	protein interactions	6536	16	1	19454	50	PRKCA
4.035e-02	-3.21	GABRB3 (gamma-aminobutyric acid type A receptor subunit beta3)	protein interactions	2562	16	1	19454	50	PRKCA
4.035e-02	-3.21	SYTL2 (synaptotagmin like 2)	protein interactions	54843	16	1	19454	50	NRXN1
4.035e-02	-3.21	AMMECR1L (AMMECR1 like)	protein interactions	83607	16	1	19454	50	MACF1
4.035e-02	-3.21	Sumo3 (small ubiquitin-like modifier 3)	protein interactions	20610	16	1	19454	50	ITPR2
4.035e-02	-3.21	GALNT13 (polypeptide N-acetylgalactosaminyltransferase 13)	protein interactions	114805	16	1	19454	50	TNIK
4.035e-02	-3.21	TWIST2 (twist family bHLH transcription factor 2)	protein interactions	117581	16	1	19454	50	ZBTB20
4.035e-02	-3.21	GABRR1 (gamma-aminobutyric acid type A receptor subunit rho1)	protein interactions	2569	16	1	19454	50	PRKCA
4.035e-02	-3.21	NRGN (neurogranin)	protein interactions	4900	16	1	19454	50	PRKCA
4.053e-02	-3.21	Cation_ATPase_C	pfam domains	PF00689	15	1	17795	49	ATP1A2
4.053e-02	-3.21	FH2	pfam domains	PF02181	15	1	17795	49	FMN2
4.053e-02	-3.21	CNH	pfam domains	PF00780	15	1	17795	49	TNIK
4.054e-02	-3.21	Circadian entrainment	KEGG pathways	hsa04713	96	2	7161	24	PRKCA,ADCY2
4.054e-02	-3.21	Circadian entrainment	KEGG pathways	ko04713	96	2	7161	24	PRKCA,ADCY2
4.083e-02	-3.20	soft_tissue-striated_muscle-rhabdomyosarcoma-alveolar	COSMIC cancer mutations	soft_tissue-striated_muscle-rhabdomyosarcoma-alveolar	2414	12	16828	49	FGFR3,PARD3B,FMN2,PREX2,CLU,PON2,CDH20,MACF1,NHSL1,NPAS3,SLC1A3,NFIA
4.083e-02	-3.20	alveolar	COSMIC cancer mutations	alveolar	2414	12	16828	49	NHSL1,FMN2,PARD3B,PREX2,NPAS3,NFIA,SLC1A3,FGFR3,CLU,MACF1,CDH20,PON2
4.099e-02	-3.19	Transport of inorganic cations/anions and amino acids/oligopeptides	REACTOME pathways	R-HSA-425393	107	2	10285	31	SLC1A3,SLC1A2
4.101e-02	-3.19	Ig-like_dom_sf	interpro domains	IPR036179	483	4	18521	50	LSAMP,NTM,NTRK2,FGFR3
4.106e-02	-3.19	SOCS6 (suppressor of cytokine signaling 6)	protein interactions	9306	125	2	19454	50	BMPR1B,EFEMP1
4.106e-02	-3.19	SLAMF1 (signaling lymphocytic activation molecule family member 1)	protein interactions	6504	125	2	19454	50	LIFR,CPE
4.106e-02	-3.19	SCGB1D1 (secretoglobin family 1D member 1)	protein interactions	10648	125	2	19454	50	CPE,LIFR
4.106e-02	-3.19	STXBP1 (syntaxin binding protein 1)	protein interactions	6812	125	2	19454	50	GPM6A,PRKCA
4.112e-02	-3.19	export from cell	biological process	GO:0140352	485	4	18204	49	ATP1A2,CPE,NTRK2,NRXN1
4.117e-02	-3.19	signaling receptor binding	molecular function	GO:0005102	1493	8	18094	48	EFEMP1,PTPRZ1,NRXN1,LIFR,PRKCA,NRG3,CPE,CLU
4.118e-02	-3.19	skin-extremity-malignant_melanoma	COSMIC cancer mutations	skin-extremity-malignant_melanoma	1875	10	16828	49	FMN2,PCDH9,ADCY2,PTPRZ1,CDH20,PREX2,FBXL7,PITPNC1,ATP13A4,NTRK2
4.121e-02	-3.19	basal_(triple-negative)_carcinoma	COSMIC cancer mutations	basal_(triple-negative)_carcinoma	2981	14	16828	49	PRKCA,NRG3,NTM,MACF1,PON2,FGFR3,ADCY2,ATP1A2,NPAS3,NTRK2,LIFR,FMN2,MSI2,BMPR1B
4.121e-02	-3.19	breast-carcinoma-basal_(triple-negative)_carcinoma	COSMIC cancer mutations	breast-carcinoma-basal_(triple-negative)_carcinoma	2981	14	16828	49	BMPR1B,MSI2,FMN2,LIFR,NTRK2,NPAS3,PON2,NTM,MACF1,NRG3,PRKCA,ATP1A2,ADCY2,FGFR3
4.131e-02	-3.19	Phosphatidylinositol signaling system	KEGG pathways	hsa04070	97	2	7161	24	PRKCA,ITPR2
4.131e-02	-3.19	Phosphatidylinositol signaling system	KEGG pathways	ko04070	97	2	7161	24	PRKCA,ITPR2
4.133e-02	-3.19	Cadherins	gene3d domains	2.60.40.60	114	2	14470	41	CDH20,PCDH9
4.141e-02	-3.18	Synthesis of PE	REACTOME pathways	R-HSA-1483213	14	1	10285	31	ETNPPL
4.141e-02	-3.18	SHC1 events in ERBB4 signaling	REACTOME pathways	R-HSA-1250347	14	1	10285	31	NRG3
4.144e-02	-3.18	striated muscle contraction	biological process	GO:0006941	120	2	18204	49	ATP1A2,DTNA
4.146e-02	-3.18	upper_leg	COSMIC cancer mutations	upper_leg	880	6	16828	49	GLIS3,PREX2,FMN2,PCDH9,FGFR3,NFIA
4.152e-02	-3.18	PROTEIN_KINASE_TYR	prosite domains	PS00109	94	2	12186	42	FGFR3,NTRK2
4.163e-02	-3.18	oxysterol binding	molecular function	GO:0008142	16	1	18094	48	RORA
4.163e-02	-3.18	misfolded protein binding	molecular function	GO:0051787	16	1	18094	48	CLU
4.163e-02	-3.18	diacylglycerol-dependent serine/threonine kinase activity	molecular function	GO:0004697	16	1	18094	48	PRKCA
4.163e-02	-3.18	adenylate cyclase activity	molecular function	GO:0004016	16	1	18094	48	ADCY2
4.163e-02	-3.18	water channel activity	molecular function	GO:0015250	16	1	18094	48	AQP4
4.166e-02	-3.18	ETV3 (ETS variant transcription factor 3)	protein interactions	2117	126	2	19454	50	NFIB,NFIA
4.166e-02	-3.18	SYP (synaptophysin)	protein interactions	6855	126	2	19454	50	PITPNC1,GPM6A
4.169e-02	-3.18	Formin, FH2 domain	gene3d domains	1.20.58.2220	15	1	14470	41	FMN2
4.198e-02	-3.17	ossification	biological process	GO:0001503	287	3	18204	49	BMPR1B,CSGALNACT1,FGFR3
4.209e-02	-3.17	Estrogen signaling pathway	KEGG pathways	ko04915	98	2	7161	24	ADCY2,ITPR2
4.209e-02	-3.17	Estrogen signaling pathway	KEGG pathways	hsa04915	98	2	7161	24	ADCY2,ITPR2
4.223e-02	-3.16	asymmetric cell division	biological process	GO:0008356	16	1	18204	49	SOX5
4.223e-02	-3.16	glutamine family amino acid biosynthetic process	biological process	GO:0009084	16	1	18204	49	GLUD1
4.223e-02	-3.16	regulation of amino acid import across plasma membrane	biological process	GO:0010958	16	1	18204	49	ATP1A2
4.223e-02	-3.16	regulation of amino acid transmembrane transport	biological process	GO:1903789	16	1	18204	49	ATP1A2
4.223e-02	-3.16	cardiac left ventricle morphogenesis	biological process	GO:0003214	16	1	18204	49	CPE
4.223e-02	-3.16	tricarboxylic acid metabolic process	biological process	GO:0072350	16	1	18204	49	GLUD1
4.223e-02	-3.16	neuron cell-cell adhesion	biological process	GO:0007158	16	1	18204	49	NRXN1
4.223e-02	-3.16	insulin metabolic process	biological process	GO:1901142	16	1	18204	49	CPE
4.223e-02	-3.16	non-proteinogenic amino acid biosynthetic process	biological process	GO:0170043	16	1	18204	49	SLC1A3
4.223e-02	-3.16	locomotory exploration behavior	biological process	GO:0035641	16	1	18204	49	ATP1A2
4.223e-02	-3.16	positive regulation of macrophage differentiation	biological process	GO:0045651	16	1	18204	49	PRKCA
4.223e-02	-3.16	regulation of respiratory system process	biological process	GO:0044065	16	1	18204	49	ATP1A2
4.223e-02	-3.16	nonribosomal peptide biosynthetic process	biological process	GO:0019184	16	1	18204	49	SLC1A2
4.223e-02	-3.16	large_intestine-adenoma	COSMIC cancer mutations	large_intestine-adenoma	266	3	16828	49	SOX5,CDH20,LIFR
4.226e-02	-3.16	EPB41L4A (erythrocyte membrane protein band 4.1 like 4A)	protein interactions	64097	127	2	19454	50	MACF1,DTNA
4.231e-02	-3.16	positive regulation of gene expression	biological process	GO:0010628	1212	7	18204	49	QKI,NTRK2,RBMS3,CLU,RORA,BMPR1B,ZBTB20
4.235e-02	-3.16	CarboxyPept-like_regulatory	interpro domains	IPR008969	16	1	18521	50	CPE
4.250e-02	-3.16	lung-middle_lobe-carcinoma-adenocarcinoma	COSMIC cancer mutations	lung-middle_lobe-carcinoma-adenocarcinoma	1368	8	16828	49	ITPR2,ATP13A4,CTNND2,MACF1,CPE,PCDH9,ATP1A2,PARD3B
4.261e-02	-3.16	Gastrin-CREB signalling pathway via PKC and MAPK	REACTOME pathways	R-HSA-881907	443	4	10285	31	PRKCA,ITPR2,NRG3,FGFR3
4.267e-02	-3.15	neuron projection terminus	cellular component	GO:0044306	128	2	19108	49	NTRK2,SLC1A2
4.273e-02	-3.15	apical dendrite	cellular component	GO:0097440	17	1	19108	49	CLU
4.282e-02	-3.15	ureter	COSMIC cancer mutations	ureter	15	1	16828	49	FGFR3
4.282e-02	-3.15	hypothalamus	COSMIC cancer mutations	hypothalamus	15	1	16828	49	QKI
4.282e-02	-3.15	PDE7A (phosphodiesterase 7A)	protein interactions	5150	17	1	19454	50	PRKCA
4.282e-02	-3.15	ZNF358 (zinc finger protein 358)	protein interactions	140467	17	1	19454	50	EFEMP1
4.282e-02	-3.15	MSANTD2 (Myb/SANT DNA binding domain containing 2)	protein interactions	79684	17	1	19454	50	SOX5
4.282e-02	-3.15	PAX4 (paired box 4)	protein interactions	5078	17	1	19454	50	NTM
4.282e-02	-3.15	TNNT2 (troponin T2, cardiac type)	protein interactions	7139	17	1	19454	50	PRKCA
4.282e-02	-3.15	Sqstm1 (sequestosome 1)	protein interactions	18412	17	1	19454	50	BMPR1B
4.282e-02	-3.15	DPP6 (dipeptidyl peptidase like 6)	protein interactions	1804	17	1	19454	50	GPM6A
4.282e-02	-3.15	CYP3A4 (cytochrome P450 family 3 subfamily A member 4)	protein interactions	1576	17	1	19454	50	PRKCA
4.282e-02	-3.15	Pef1 (penta-EF hand domain containing 1)	protein interactions	67898	17	1	19454	50	QKI
4.282e-02	-3.15	TAGAP (T cell activation RhoGTPase activating protein)	protein interactions	117289	17	1	19454	50	DTNA
4.282e-02	-3.15	RASL12 (RAS like family 12)	protein interactions	51285	17	1	19454	50	BMPR1B
4.282e-02	-3.15	LIPT1 (lipoyltransferase 1)	protein interactions	51601	17	1	19454	50	PRKCA
4.286e-02	-3.15	PRKAR2B (protein kinase cAMP-dependent type II regulatory subunit beta)	protein interactions	5577	128	2	19454	50	PRKCA,GPM6A
4.286e-02	-3.15	ATF7IP (activating transcription factor 7 interacting protein)	protein interactions	55729	128	2	19454	50	MACF1,SOX5
4.311e-02	-3.14	human chr5p15.31	chromosome location	human chr5p15.31	23	1	26134	50	ADCY2
4.311e-02	-3.14	Intracellular Signalling Through LHCGR Receptor and Luteinizing Hormone/Choriogonadotropin	SMPDB pathways	SMP0000338	10	1	1369	6	ADCY2
4.321e-02	-3.14	CARM1 (coactivator associated arginine methyltransferase 1)	protein interactions	10498	304	3	19454	50	DTNA,QKI,RORA
4.346e-02	-3.14	Lima1 (LIM domain and actin binding 1)	protein interactions	65970	129	2	19454	50	ITPR2,ZBTB20
4.346e-02	-3.14	ZNF148 (zinc finger protein 148)	protein interactions	7707	129	2	19454	50	NFIB,NFIA
4.346e-02	-3.14	CHD7 (chromodomain helicase DNA binding protein 7)	protein interactions	55636	129	2	19454	50	ZBTB20,SOX5
4.346e-02	-3.14	POLA2 (DNA polymerase alpha 2, accessory subunit)	protein interactions	23649	129	2	19454	50	FGFR3,CPE
4.368e-02	-3.13	pleura-mesothelioma	COSMIC cancer mutations	pleura-mesothelioma	4189	18	16828	49	NFIB,QKI,ITPR2,NTRK2,FGFR3,RORA,FBXL7,PRKCA,CLU,BMPR1B,PITPNC1,LIFR,TNIK,MSI2,SOX5,CTNND2,PREX2,PTPRZ1
4.381e-02	-3.13	response to hypoxia	biological process	GO:0001666	292	3	18204	49	ITPR2,FMN2,RORA
4.391e-02	-3.13	CARBOXYPEPT_ZN_2	prosite domains	PS00133	13	1	12186	42	CPE
4.391e-02	-3.13	CARBOXYPEPT_ZN_1	prosite domains	PS00132	13	1	12186	42	CPE
4.397e-02	-3.12	action potential	biological process	GO:0001508	124	2	18204	49	ATP1A2,NTRK2
4.417e-02	-3.12	transmembrane receptor protein phosphatase activity	molecular function	GO:0019198	17	1	18094	48	PTPRZ1
4.417e-02	-3.12	transmembrane receptor protein tyrosine phosphatase activity	molecular function	GO:0005001	17	1	18094	48	PTPRZ1
4.427e-02	-3.12	TMEM106B (transmembrane protein 106B)	protein interactions	54664	307	3	19454	50	CLU,EFEMP1,PON2
4.430e-02	-3.12	ERBB2 Regulates Cell Motility	REACTOME pathways	R-HSA-6785631	15	1	10285	31	NRG3
4.430e-02	-3.12	Depolymerisation of the Nuclear Lamina	REACTOME pathways	R-HSA-4419969	15	1	10285	31	PRKCA
4.430e-02	-3.12	Adenylate cyclase inhibitory pathway	REACTOME pathways	R-HSA-170670	15	1	10285	31	ADCY2
4.430e-02	-3.12	N-Glycan antennae elongation	REACTOME pathways	R-HSA-975577	15	1	10285	31	MGAT4C
4.430e-02	-3.12	Inhibition of adenylate cyclase pathway	REACTOME pathways	R-HSA-997269	15	1	10285	31	ADCY2
4.430e-02	-3.12	WNT5A-dependent internalization of FZD4	REACTOME pathways	R-HSA-5099900	15	1	10285	31	PRKCA
4.445e-02	-3.11	Melanogenesis	KEGG pathways	ko04916	101	2	7161	24	PRKCA,ADCY2
4.445e-02	-3.11	Melanogenesis	KEGG pathways	hsa04916	101	2	7161	24	ADCY2,PRKCA
4.448e-02	-3.11	PDZ	pfam domains	PF00595	122	2	17795	49	PREX2,PARD3B
4.468e-02	-3.11	NCOA2 (nuclear receptor coactivator 2)	protein interactions	10499	131	2	19454	50	NFIA,RORA
4.481e-02	-3.11	membrane depolarization during cardiac muscle cell action potential	biological process	GO:0086012	17	1	18204	49	ATP1A2
4.481e-02	-3.11	cell communication by electrical coupling involved in cardiac conduction	biological process	GO:0086064	17	1	18204	49	ATP1A2
4.481e-02	-3.11	cGMP metabolic process	biological process	GO:0046068	17	1	18204	49	RORA
4.481e-02	-3.11	protein trimerization	biological process	GO:0070206	17	1	18204	49	SLC1A2
4.481e-02	-3.11	regulation of amyloid fibril formation	biological process	GO:1905906	17	1	18204	49	CLU
4.481e-02	-3.11	viral genome replication	biological process	GO:0019079	17	1	18204	49	NFIA
4.481e-02	-3.11	microvillus assembly	biological process	GO:0030033	17	1	18204	49	TNIK
4.481e-02	-3.11	reverse cholesterol transport	biological process	GO:0043691	17	1	18204	49	CLU
4.481e-02	-3.11	retinal rod cell differentiation	biological process	GO:0060221	17	1	18204	49	NTRK2
4.481e-02	-3.11	T-helper 17 type immune response	biological process	GO:0072538	17	1	18204	49	RORA
4.481e-02	-3.11	ureter development	biological process	GO:0072189	17	1	18204	49	NFIA
4.481e-02	-3.11	heparin metabolic process	biological process	GO:0030202	17	1	18204	49	CSGALNACT1
4.481e-02	-3.11	regulation of inclusion body assembly	biological process	GO:0090083	17	1	18204	49	CLU
4.493e-02	-3.10	regulation of ERK1 and ERK2 cascade	biological process	GO:0070372	295	3	18204	49	PRKCA,FGFR3,NTRK2
4.493e-02	-3.10	A/G_cyclase_CS	interpro domains	IPR018297	17	1	18521	50	ADCY2
4.493e-02	-3.10	CA_dom_sf	interpro domains	IPR036398	17	1	18521	50	PTPRZ1
4.493e-02	-3.10	CA_dom	interpro domains	IPR001148	17	1	18521	50	PTPRZ1
4.499e-02	-3.10	AFDN (afadin, adherens junction formation factor)	protein interactions	4301	309	3	19454	50	MACF1,DTNA,NRXN1
4.507e-02	-3.10	ductal_carcinoma	COSMIC cancer mutations	ductal_carcinoma	15798	49	16828	49	RBMS3,ADCY2,NTM,FBXL7,CLU,CSGALNACT1,PCDH9,FMN2,ZBTB20,SFXN5,CTNND2,PREX2,DTNA,GPM6A,AQP4,ATP1A2,FGFR3,PON2,NRG3,NHSL1,NKAIN3,CPE,PTPRZ1,SLC1A2,NFIB,NTRK2,NRXN1,SLC1A3,MGAT4C,EFEMP1,RORA,LSAMP,CDH20,PITPNC1,ATP13A4,BMPR1B,GLUD1,TNIK,LIFR,PARD3B,MSI2,QKI,NFIA,ITPR2,NPAS3,GLIS3,MACF1,PRKCA,SOX5
4.525e-02	-3.10	Glucagon signaling pathway	KEGG pathways	ko04922	102	2	7161	24	ADCY2,ITPR2
4.525e-02	-3.10	Glucagon signaling pathway	KEGG pathways	hsa04922	102	2	7161	24	ADCY2,ITPR2
4.529e-02	-3.09	SELL (selectin L)	protein interactions	6402	18	1	19454	50	PRKCA
4.529e-02	-3.09	NKIRAS1 (NFKB inhibitor interacting Ras like 1)	protein interactions	28512	18	1	19454	50	BMPR1B
4.529e-02	-3.09	Cnot2 (CCR4-NOT transcription complex, subunit 2)	protein interactions	72068	18	1	19454	50	MACF1
4.529e-02	-3.09	CYP2E1 (cytochrome P450 family 2 subfamily E member 1)	protein interactions	1571	18	1	19454	50	CLU
4.529e-02	-3.09	Tgfbr1 (transforming growth factor, beta receptor I)	protein interactions	21812	18	1	19454	50	BMPR1B
4.529e-02	-3.09	TTC29 (tetratricopeptide repeat domain 29)	protein interactions	83894	18	1	19454	50	MACF1
4.529e-02	-3.09	OPCML (opioid binding protein/cell adhesion molecule like)	protein interactions	4978	18	1	19454	50	NTM
4.529e-02	-3.09	KLHL1 (kelch like family member 1)	protein interactions	57626	18	1	19454	50	BMPR1B
4.529e-02	-3.09	NECTIN1 (nectin cell adhesion molecule 1)	protein interactions	5818	18	1	19454	50	FGFR3
4.530e-02	-3.09	DDR2 (discoidin domain receptor tyrosine kinase 2)	protein interactions	4921	132	2	19454	50	CLU,GLUD1
4.530e-02	-3.09	GPIHBP1 (glycosylphosphatidylinositol anchored high density lipoprotein binding protein 1)	protein interactions	338328	132	2	19454	50	FGFR3,CPE
4.533e-02	-3.09	purine ribonucleoside triphosphate binding	molecular function	GO:0035639	1804	9	18094	48	NTRK2,ATP1A2,ADCY2,TNIK,ATP13A4,BMPR1B,FGFR3,GLUD1,PRKCA
4.561e-02	-3.09	flank	COSMIC cancer mutations	flank	16	1	16828	49	FGFR3
4.561e-02	-3.09	renal_pelvis	COSMIC cancer mutations	renal_pelvis	16	1	16828	49	FGFR3
4.561e-02	-3.09	normal	COSMIC cancer mutations	normal	16	1	16828	49	FGFR3
4.561e-02	-3.09	urinary_tract-carcinoma	COSMIC cancer mutations	urinary_tract-carcinoma	16	1	16828	49	FGFR3
4.573e-02	-3.08	carbohydrate derivative metabolic process	biological process	GO:1901135	975	6	18204	49	MGAT4C,BMPR1B,RORA,CSGALNACT1,ADCY2,ATP1A2
4.581e-02	-3.08	ZZ	pfam domains	PF00569	17	1	17795	49	DTNA
4.581e-02	-3.08	Carb_anhydrase	pfam domains	PF00194	17	1	17795	49	PTPRZ1
4.582e-02	-3.08	EZR (ezrin)	protein interactions	7430	526	4	19454	50	PRKCA,TNIK,MACF1,DTNA
4.590e-02	-3.08	cell-cell junction assembly	biological process	GO:0007043	127	2	18204	49	CDH20,PRKCA
4.590e-02	-3.08	response to amino acid	biological process	GO:0043200	127	2	18204	49	SLC1A2,NTRK2
4.590e-02	-3.08	regulation of myeloid leukocyte differentiation	biological process	GO:0002761	127	2	18204	49	PRKCA,QKI
4.615e-02	-3.08	cell cortex	cellular component	GO:0005938	313	3	19108	49	FMN2,ITPR2,PARD3B
4.634e-02	-3.07	Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour	COSMIC cancer mutations	Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour	7434	28	16828	49	NKAIN3,PTPRZ1,SOX5,ITPR2,NPAS3,DTNA,QKI,GLIS3,MACF1,PON2,NRG3,ATP1A2,FGFR3,CSGALNACT1,ATP13A4,CTNND2,PREX2,FMN2,TNIK,LIFR,PARD3B,ZBTB20,SLC1A3,NRXN1,NTRK2,NFIB,RORA,ADCY2
4.642e-02	-3.07	ASX_HYDROXYL	prosite domains	PS00010	100	2	12186	42	NRXN1,EFEMP1
4.655e-02	-3.07	glial cell development	biological process	GO:0021782	128	2	18204	49	CLU,NTRK2
4.671e-02	-3.06	transmembrane receptor protein tyrosine kinase activator activity	molecular function	GO:0030297	18	1	18094	48	NRG3
4.671e-02	-3.06	intracellularly gated calcium channel activity	molecular function	GO:0015278	18	1	18094	48	ITPR2
4.671e-02	-3.06	NAD+ binding	molecular function	GO:0070403	18	1	18094	48	GLUD1
4.671e-02	-3.06	phosphatidylcholine transporter activity	molecular function	GO:0008525	18	1	18094	48	PITPNC1
4.683e-02	-3.06	RET signaling	REACTOME pathways	R-HSA-8853659	270	3	10285	31	PRKCA,FGFR3,NRG3
4.712e-02	-3.06	Alpha carbonic anhydrase	gene3d domains	3.10.200.10	17	1	14470	41	PTPRZ1
4.716e-02	-3.05	NTRK2 (neurotrophic receptor tyrosine kinase 2)	protein interactions	4915	135	2	19454	50	DTNA,NTRK2
4.716e-02	-3.05	SOX15 (SRY-box transcription factor 15)	protein interactions	6665	135	2	19454	50	NFIA,NFIB
4.716e-02	-3.05	BMP4 (bone morphogenetic protein 4)	protein interactions	652	135	2	19454	50	BMPR1B,CLU
4.718e-02	-3.05	Regulation of KIT signaling	REACTOME pathways	R-HSA-1433559	16	1	10285	31	PRKCA
4.718e-02	-3.05	PKA activation	REACTOME pathways	R-HSA-163615	16	1	10285	31	ADCY2
4.718e-02	-3.05	PI3K events in ERBB2 signaling	REACTOME pathways	R-HSA-1963642	16	1	10285	31	NRG3
4.718e-02	-3.05	GRB2 events in ERBB2 signaling	REACTOME pathways	R-HSA-1963640	16	1	10285	31	NRG3
4.722e-02	-3.05	central_nervous_system-brain-glioma-astrocytoma_Grade_IV	COSMIC cancer mutations	central_nervous_system-brain-glioma-astrocytoma_Grade_IV	15813	49	16828	49	MGAT4C,NRXN1,NTRK2,SLC1A3,NFIB,SLC1A2,CDH20,RORA,EFEMP1,LSAMP,GLUD1,BMPR1B,ATP13A4,PITPNC1,TNIK,LIFR,PARD3B,MSI2,NPAS3,NFIA,ITPR2,QKI,PRKCA,MACF1,GLIS3,SOX5,RBMS3,FBXL7,CLU,NTM,ADCY2,CSGALNACT1,PREX2,CTNND2,SFXN5,PCDH9,FMN2,ZBTB20,DTNA,NRG3,PON2,FGFR3,GPM6A,AQP4,ATP1A2,NKAIN3,NHSL1,PTPRZ1,CPE
4.734e-02	-3.05	NAD+ Signalling and Aging	SMPDB pathways	SMP0084271	11	1	1369	6	RORA
4.734e-02	-3.05	Ammonia Recycling	SMPDB pathways	SMP0000009	11	1	1369	6	GLUD1
4.738e-02	-3.05	response to misfolded protein	biological process	GO:0051788	18	1	18204	49	CLU
4.738e-02	-3.05	myelin maintenance	biological process	GO:0043217	18	1	18204	49	CLU
4.738e-02	-3.05	negative regulation of sodium ion transport	biological process	GO:0010766	18	1	18204	49	ATP1A2
4.738e-02	-3.05	positive regulation of circadian rhythm	biological process	GO:0042753	18	1	18204	49	RORA
4.738e-02	-3.05	dendritic spine morphogenesis	biological process	GO:0060997	18	1	18204	49	CTNND2
4.738e-02	-3.05	negative regulation of anoikis	biological process	GO:2000811	18	1	18204	49	NTRK2
4.738e-02	-3.05	dicarboxylic acid catabolic process	biological process	GO:0043649	18	1	18204	49	GLUD1
4.743e-02	-3.05	striated_muscle	COSMIC cancer mutations	striated_muscle	4228	18	16828	49	CTNND2,PREX2,PTPRZ1,PARD3B,FMN2,NHSL1,CLU,PON2,MACF1,CDH20,GLIS3,ADCY2,FGFR3,RORA,AQP4,NPAS3,SLC1A3,NFIA
4.749e-02	-3.05	positive regulation of cell communication	biological process	GO:0010647	1792	9	18204	49	BMPR1B,GLUD1,NRXN1,FGFR3,SLC1A3,NTRK2,TNIK,MACF1,PRKCA
4.752e-02	-3.05	Nucleotide_cyclase	interpro domains	IPR029787	18	1	18521	50	ADCY2
4.752e-02	-3.05	Leu-rich_rpt_Cys-con_subtyp	interpro domains	IPR006553	18	1	18521	50	FBXL7
4.752e-02	-3.05	A/G_cyclase	interpro domains	IPR001054	18	1	18521	50	ADCY2
4.761e-02	-3.04	postsynaptic density	cellular component	GO:0014069	317	3	19108	49	CTNND2,NTRK2,TNIK
4.764e-02	-3.04	postsynaptic specialization, intracellular component	cellular component	GO:0099091	19	1	19108	49	TNIK
4.764e-02	-3.04	parallel fiber to Purkinje cell synapse	cellular component	GO:0098688	19	1	19108	49	GPM6A
4.764e-02	-3.04	cation-transporting ATPase complex	cellular component	GO:0090533	19	1	19108	49	ATP1A2
4.768e-02	-3.04	primary_central_nervous_system_lymphoma	COSMIC cancer mutations	primary_central_nervous_system_lymphoma	683	5	16828	49	PARD3B,ZBTB20,NRG3,NRXN1,MACF1
4.768e-02	-3.04	haematopoietic_and_lymphoid_tissue-central_nervous_system-lymphoid_neoplasm-primary_central_nervous_system_lymphoma	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue-central_nervous_system-lymphoid_neoplasm-primary_central_nervous_system_lymphoma	683	5	16828	49	NRG3,MACF1,NRXN1,PARD3B,ZBTB20
4.769e-02	-3.04	SMURF1 (SMAD specific E3 ubiquitin protein ligase 1)	protein interactions	57154	533	4	19454	50	FMN2,TNIK,BMPR1B,PRKCA
4.772e-02	-3.04	haematopoietic_and_lymphoid_tissue-abdomen-lymphoid_neoplasm-diffuse_large_B_cell_lymphoma	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue-abdomen-lymphoid_neoplasm-diffuse_large_B_cell_lymphoma	120	2	16828	49	FMN2,CTNND2
4.774e-02	-3.04	TNR (tenascin R)	protein interactions	7143	19	1	19454	50	PTPRZ1
4.774e-02	-3.04	JSRP1 (junctional sarcoplasmic reticulum protein 1)	protein interactions	126306	19	1	19454	50	PRKCA
4.774e-02	-3.04	ZNF627 (zinc finger protein 627)	protein interactions	199692	19	1	19454	50	EFEMP1
4.774e-02	-3.04	SPZ1 (spermatogenic leucine zipper 1)	protein interactions	84654	19	1	19454	50	DTNA
4.774e-02	-3.04	RIT2 (Ras like without CAAX 2)	protein interactions	6014	19	1	19454	50	DTNA
4.774e-02	-3.04	PHYHIPL (phytanoyl-CoA 2-hydroxylase interacting protein like)	protein interactions	84457	19	1	19454	50	GPM6A
4.774e-02	-3.04	C3orf62 (chromosome 3 open reading frame 62)	protein interactions	375341	19	1	19454	50	ATP1A2
4.774e-02	-3.04	CNTNAP4 (contactin associated protein family member 4)	protein interactions	85445	19	1	19454	50	MACF1
4.774e-02	-3.04	OSM (oncostatin M)	protein interactions	5008	19	1	19454	50	LIFR
4.774e-02	-3.04	RRAD (RRAD, Ras related glycolysis inhibitor and calcium channel regulator)	protein interactions	6236	19	1	19454	50	PRKCA
4.774e-02	-3.04	SYT7 (synaptotagmin 7)	protein interactions	9066	19	1	19454	50	NRXN1
4.774e-02	-3.04	TRPV6 (transient receptor potential cation channel subfamily V member 6)	protein interactions	55503	19	1	19454	50	PRKCA
4.774e-02	-3.04	FBXO27 (F-box protein 27)	protein interactions	126433	19	1	19454	50	CLU
4.774e-02	-3.04	NLGN1 (neuroligin 1)	protein interactions	22871	19	1	19454	50	NRXN1
4.774e-02	-3.04	INKA1 (inka box actin regulator 1)	protein interactions	389119	19	1	19454	50	ZBTB20
4.774e-02	-3.04	ZNF791 (zinc finger protein 791)	protein interactions	163049	19	1	19454	50	EFEMP1
4.777e-02	-3.04	positive regulation of signaling	biological process	GO:0023056	1794	9	18204	49	SLC1A3,FGFR3,GLUD1,NRXN1,BMPR1B,MACF1,PRKCA,TNIK,NTRK2
4.793e-02	-3.04	skin-back-malignant_melanoma	COSMIC cancer mutations	skin-back-malignant_melanoma	280	3	16828	49	PREX2,ATP1A2,TNIK
4.822e-02	-3.03	mitotic cell cycle process	biological process	GO:1903047	511	4	18204	49	FBXL7,NFIB,NFIA,PRKCA
4.839e-02	-3.03	squamous_cell_carcinoma_BRAF_inhibitor_related	COSMIC cancer mutations	squamous_cell_carcinoma_BRAF_inhibitor_related	17	1	16828	49	FGFR3
4.839e-02	-3.03	skin-other-verrucal_keratosis_BRAF_inhibitor_related	COSMIC cancer mutations	skin-other-verrucal_keratosis_BRAF_inhibitor_related	17	1	16828	49	FGFR3
4.839e-02	-3.03	skin-non_chronically_sun_exposed_site-malignant_melanoma	COSMIC cancer mutations	skin-non_chronically_sun_exposed_site-malignant_melanoma	17	1	16828	49	FGFR3
4.839e-02	-3.03	skin-carcinoma-squamous_cell_carcinoma_BRAF_inhibitor_related	COSMIC cancer mutations	skin-carcinoma-squamous_cell_carcinoma_BRAF_inhibitor_related	17	1	16828	49	FGFR3
4.839e-02	-3.03	breast-carcinoma-neuroendocrine_carcinoma	COSMIC cancer mutations	breast-carcinoma-neuroendocrine_carcinoma	17	1	16828	49	FGFR3
4.839e-02	-3.03	central_nervous_system-optic_nerve-glioma-astrocytoma_Grade_I	COSMIC cancer mutations	central_nervous_system-optic_nerve-glioma-astrocytoma_Grade_I	17	1	16828	49	QKI
4.839e-02	-3.03	non_chronically_sun_exposed_site	COSMIC cancer mutations	non_chronically_sun_exposed_site	17	1	16828	49	FGFR3
4.839e-02	-3.03	optic_nerve	COSMIC cancer mutations	optic_nerve	17	1	16828	49	QKI
4.839e-02	-3.03	verrucal_keratosis_BRAF_inhibitor_related	COSMIC cancer mutations	verrucal_keratosis_BRAF_inhibitor_related	17	1	16828	49	FGFR3
4.842e-02	-3.03	Bmpr1a (bone morphogenetic protein receptor, type 1A)	protein interactions	12166	137	2	19454	50	LIFR,GLUD1
4.842e-02	-3.03	CLUH (clustered mitochondria homolog)	protein interactions	23277	137	2	19454	50	PRKCA,FGFR3
4.843e-02	-3.03	Ras signaling in the CD4+ TCR pathway	Pathway Interaction DB	tcrraspathway	11	1	2226	10	PRKCA
4.844e-02	-3.03	Guanylate_cyc	pfam domains	PF00211	18	1	17795	49	ADCY2
4.852e-02	-3.03	carboxylic acid transmembrane transport	biological process	GO:1905039	131	2	18204	49	SLC1A3,SLC1A2
4.856e-02	-3.02	protein-folding chaperone binding	molecular function	GO:0051087	133	2	18094	48	ATP1A2,CLU
4.859e-02	-3.02	human chr18q12.1	chromosome location	human chr18q12.1	26	1	26134	50	DTNA
4.859e-02	-3.02	human chr2p16.1	chromosome location	human chr2p16.1	26	1	26134	50	EFEMP1
4.865e-02	-3.02	Bone Morphogenic Protein (BMP) Signalling and Regulation	WikiPathways	WP1425	12	1	5310	22	BMPR1B
4.905e-02	-3.01	NFIB (nuclear factor I B)	protein interactions	4781	138	2	19454	50	NFIA,SOX5
4.916e-02	-3.01	response to decreased oxygen levels	biological process	GO:0036293	306	3	18204	49	RORA,ITPR2,FMN2
4.924e-02	-3.01	water transmembrane transporter activity	molecular function	GO:0005372	19	1	18094	48	AQP4
4.924e-02	-3.01	alkali metal ion binding	molecular function	GO:0031420	19	1	18094	48	ATP1A2
4.924e-02	-3.01	transmembrane receptor protein serine/threonine kinase activity	molecular function	GO:0004675	19	1	18094	48	BMPR1B
4.931e-02	-3.01	TRIM67 (tripartite motif containing 67)	protein interactions	440730	4804	18	19454	50	SLC1A3,ATP1A2,GLUD1,GPM6A,LSAMP,PITPNC1,DTNA,PON2,CLU,NTM,ITPR2,TNIK,PRKCA,QKI,MSI2,PTPRZ1,MACF1,CTNND2
4.940e-02	-3.01	ACTA1 (actin alpha 1, skeletal muscle)	protein interactions	58	321	3	19454	50	PRKCA,MACF1,DTNA
4.962e-02	-3.00	thalamus	COSMIC cancer mutations	thalamus	284	3	16828	49	FGFR3,QKI,DTNA
4.966e-02	-3.00	cell division	biological process	GO:0051301	516	4	18204	49	PARD3B,SOX5,FBXL7,FMN2
4.982e-02	-3.00	Nucleotide cyclase	gene3d domains	3.30.70.1230	18	1	14470	41	ADCY2
4.985e-02	-3.00	regulation of sequestering of calcium ion	biological process	GO:0051282	133	2	18204	49	ATP1A2,ITPR2
4.995e-02	-3.00	microvillus organization	biological process	GO:0032528	19	1	18204	49	TNIK
4.995e-02	-3.00	regulation of amyloid-beta clearance	biological process	GO:1900221	19	1	18204	49	CLU
4.995e-02	-3.00	positive regulation of bone resorption	biological process	GO:0045780	19	1	18204	49	PRKCA
4.995e-02	-3.00	chondroitin sulfate biosynthetic process	biological process	GO:0030206	19	1	18204	49	CSGALNACT1
4.995e-02	-3.00	vascular associated smooth muscle cell differentiation	biological process	GO:0035886	19	1	18204	49	QKI
4.995e-02	-3.00	cerebellar Purkinje cell layer morphogenesis	biological process	GO:0021692	19	1	18204	49	RORA
4.995e-02	-3.00	excitatory synapse assembly	biological process	GO:1904861	19	1	18204	49	NRXN1
4.995e-02	-3.00	regulation of neurotransmitter uptake	biological process	GO:0051580	19	1	18204	49	ATP1A2
4.995e-02	-3.00	vocalization behavior	biological process	GO:0071625	19	1	18204	49	NRXN1
4.995e-02	-3.00	response to potassium ion	biological process	GO:0035864	19	1	18204	49	ATP1A2