Gene Ontology Enrichment Results

Homer de novo Motif Enrichment Results
Known Motif Enrichment Results

Text file version of complete results (i.e. open with Excel)

biological process: Functional groupings of proteins (Gene Ontology)

molecular function: Mechanistic actions of proteins (Gene Ontology)

cellular component: Protein localization (Gene Ontology)

chromosome location: Genes with similar chromosome localization (NCBI Gene)

KEGG pathways: Groups of proteins in the same pathways (KEGG)

protein interactions: "Proteins interacting with a common protein (BIND, EcoCyc, HPRD)" (NCBI Gene)

interpro domains: Proteins with similar domains and features (Interpro)

pfam domains: Proteins with similar domains and features (Pfam)

smart domains: Proteins with similar domains and features (SMART)

gene3d domains: Proteins with similar domains and features (Gene3D)

prosite domains: Proteins with similar domains and features (Prosite)

prints domains: Proteins with similar domains and features (PRINTS)

MSigDB lists: "Genes sets for pathways, factor/miRNA target predictions, expression patterns, etc." (MSigDB)

BIOCYC pathways: Groups of proteins in the same pathways (BIOCYC)

COSMIC cancer mutations: Genes mutated in similar cancers (COSMIC)

GWAS genes: Genes mutated in similar diseases (GWAS Catalog)

Lipid Maps pathways: Groups of proteins in the same lipid pathways (Lipid Maps/Biosystems)

Pathway Interaction DB: Groups of proteins in the same pathways (Pathway Interaction Database)

REACTOME pathways: Groups of proteins in the same pathways (REACTOME)

SMPDB pathways: Groups of proteins in the same pathways (SMPDB)

WikiPathways: Groups of proteins in the same pathways (Wikipathways)

Enriched Categories

P-value	ln(P)	Term	GO Tree	GO ID	# of Genes in Term	# of Target Genes in Term	# of Total Genes	# of Target Genes	Common Genes
2.720e-16	-35.84	central_nervous_system-cerebellum-primitive_neuroectodermal_tumour-medulloblastoma-SHH_subtype	COSMIC cancer mutations	central_nervous_system-cerebellum-primitive_neuroectodermal_tumour-medulloblastoma-SHH_subtype	653	20	16828	48	NRG3,NTRK2,PRKG1,PLCB1,PTPRZ1,CTNND2,NRXN1,PARD3,PCDH9,NPAS3,RYR3,RGS6,HPSE2,MAGI2,LRP1B,NEBL,CPE,ERBB4,ANK2,ABLIM1
2.801e-16	-35.81	SHH_subtype	COSMIC cancer mutations	SHH_subtype	654	20	16828	48	PLCB1,CTNND2,PTPRZ1,NRG3,PRKG1,NTRK2,NPAS3,NRXN1,PCDH9,PARD3,HPSE2,RYR3,RGS6,ABLIM1,ANK2,ERBB4,NEBL,LRP1B,MAGI2,CPE
3.831e-16	-35.50	cerebellum	COSMIC cancer mutations	cerebellum	769	21	16828	48	NRXN1,PCDH9,PARD3,NPAS3,NRG3,PRKG1,NTRK2,PLCB1,CTNND2,PTPRZ1,NEBL,LRP1B,MAGI2,CPE,ABLIM1,ERBB4,ANK2,RYR3,RGS6,HPSE2,GPC5
2.127e-13	-29.18	acute_lymphoblastic_B_cell_leukaemia	COSMIC cancer mutations	acute_lymphoblastic_B_cell_leukaemia	3828	35	16828	48	RYR3,RORA,TNC,CPE,MAGI2,GPM6A,LRP1B,ANK2,TNIK,PPP2R2B,LSAMP,NFIA,CTNND2,NKAIN3,NRXN1,SLC1A2,GPC5,HPSE2,CADM2,NEBL,CNTN1,ERBB4,FMN2,NTRK2,PRKG1,NRG3,GLIS3,PTPRZ1,SOX5,NTM,MGAT4C,PLCB1,PARD3,PCDH9,ADCY2
2.127e-13	-29.18	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-acute_lymphoblastic_B_cell_leukaemia	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-acute_lymphoblastic_B_cell_leukaemia	3828	35	16828	48	PLCB1,MGAT4C,NTM,SOX5,PTPRZ1,GLIS3,NRG3,PRKG1,NTRK2,ADCY2,PCDH9,PARD3,HPSE2,GPC5,FMN2,CNTN1,ERBB4,NEBL,CADM2,CTNND2,NFIA,SLC1A2,NRXN1,NKAIN3,RORA,RYR3,PPP2R2B,LSAMP,TNIK,ANK2,LRP1B,GPM6A,MAGI2,CPE,TNC
7.941e-13	-27.86	nervous system development	biological process	GO:0007399	2185	27	18204	50	CTNNA2,SOX5,CNTN1,TNIK,PLCB1,GFAP,FUT9,NFIA,CTNND2,PTPRZ1,CLU,LSAMP,APOE,ERBB4,MAGI2,RORA,PRKG1,GPM6A,SLC1A2,NRXN1,NTM,ANK2,NRG3,PCDH9,PARD3,TNC,NTRK2
2.875e-12	-26.57	acute_myeloid_leukaemia_therapy_related	COSMIC cancer mutations	acute_myeloid_leukaemia_therapy_related	1523	23	16828	48	NKAIN3,CTNND2,LSAMP,PPP2R2B,ANK2,LRP1B,MAGI2,RORA,RYR3,ADCY2,PCDH9,PARD3,PLCB1,SOX5,NRG3,PRKG1,NTRK2,FMN2,ERBB4,NEBL,CADM2,HPSE2,GPC5
2.875e-12	-26.57	haematopoietic_and_lymphoid_tissue-haematopoietic_neoplasm-acute_myeloid_leukaemia_therapy_related	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue-haematopoietic_neoplasm-acute_myeloid_leukaemia_therapy_related	1523	23	16828	48	PCDH9,PARD3,ADCY2,PRKG1,NTRK2,NRG3,SOX5,PLCB1,CADM2,NEBL,ERBB4,FMN2,GPC5,HPSE2,NKAIN3,CTNND2,LRP1B,MAGI2,ANK2,PPP2R2B,LSAMP,RYR3,RORA
5.790e-12	-25.87	Burkitt_lymphoma	COSMIC cancer mutations	Burkitt_lymphoma	2119	26	16828	48	CTNND2,NKAIN3,SLC1A2,RYR3,CPE,LRP1B,GPM6A,MAGI2,ANK2,PPP2R2B,LSAMP,PRKG1,NTRK2,NRG3,SOX5,PLCB1,PCDH9,PARD3,NPAS3,ADCY2,GPC5,HPSE2,CADM2,ERBB4,CNTN1,FMN2
5.790e-12	-25.87	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-Burkitt_lymphoma	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-Burkitt_lymphoma	2119	26	16828	48	NRG3,PRKG1,NTRK2,PLCB1,SOX5,PCDH9,PARD3,NPAS3,ADCY2,HPSE2,GPC5,CADM2,FMN2,ERBB4,CNTN1,CTNND2,NKAIN3,SLC1A2,RYR3,LRP1B,MAGI2,GPM6A,CPE,LSAMP,PPP2R2B,ANK2
1.141e-11	-25.20	chondroblastoma	COSMIC cancer mutations	chondroblastoma	534	15	16828	48	RYR3,GPC5,LRP1B,GPM6A,FMN2,LSAMP,PPP2R2B,NRG3,PRKG1,PLCB1,CTNND2,SOX5,NKAIN3,PCDH9,ADCY2
1.265e-11	-25.09	angiosarcoma	COSMIC cancer mutations	angiosarcoma	2192	26	16828	48	CTNND2,NKAIN3,SLC1A2,CDH20,RYR3,LRP1B,MAGI2,GPM6A,ANK2,PPP2R2B,LSAMP,PRKG1,NTRK2,NRG3,SOX5,PTPRZ1,PLCB1,PCDH9,PARD3,ADCY2,GPC5,HPSE2,CADM2,NEBL,ERBB4,FMN2
1.265e-11	-25.09	soft_tissue-blood_vessel-angiosarcoma	COSMIC cancer mutations	soft_tissue-blood_vessel-angiosarcoma	2192	26	16828	48	HPSE2,GPC5,NEBL,CADM2,FMN2,ERBB4,NRG3,NTRK2,PRKG1,PLCB1,PTPRZ1,SOX5,PARD3,PCDH9,ADCY2,RYR3,CDH20,GPM6A,MAGI2,LRP1B,PPP2R2B,LSAMP,ANK2,CTNND2,NKAIN3,SLC1A2
1.403e-11	-24.99	haematopoietic_and_lymphoid_tissue-haematopoietic_neoplasm	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue-haematopoietic_neoplasm	764	17	16828	48	GPC5,HPSE2,RYR3,ERBB4,LSAMP,CADM2,MAGI2,LRP1B,SOX5,PLCB1,NTRK2,NRG3,ADCY2,SLC1A2,PARD3,PCDH9,NKAIN3
1.542e-11	-24.90	blood_vessel	COSMIC cancer mutations	blood_vessel	2211	26	16828	48	RYR3,CDH20,MAGI2,GPM6A,LRP1B,ANK2,LSAMP,PPP2R2B,CTNND2,NKAIN3,SLC1A2,GPC5,HPSE2,CADM2,NEBL,ERBB4,FMN2,NTRK2,PRKG1,NRG3,PTPRZ1,SOX5,PLCB1,PARD3,PCDH9,ADCY2
3.473e-11	-24.08	haematopoietic_and_lymphoid_tissue-lymph_node-lymphoid_neoplasm-mantle_cell_lymphoma	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue-lymph_node-lymphoid_neoplasm-mantle_cell_lymphoma	476	14	16828	48	GPC5,RYR3,TRPM3,LSAMP,ERBB4,ANK2,LRP1B,MAGI2,GPM6A,PLCB1,CTNND2,NRG3,PRKG1,PCDH9
7.335e-11	-23.34	generation of neurons	biological process	GO:0048699	1158	19	18204	50	APOE,NTRK2,TNC,PTPRZ1,PARD3,NTM,NRXN1,CTNND2,GPM6A,PRKG1,NFIA,FUT9,GFAP,RORA,TNIK,CNTN1,SOX5,ERBB4,CTNNA2
9.732e-11	-23.05	neurogenesis	biological process	GO:0022008	1334	20	18204	50	CLU,TNC,PTPRZ1,PARD3,APOE,NTRK2,PRKG1,NFIA,FUT9,GFAP,NTM,NRXN1,CTNND2,GPM6A,TNIK,RORA,CTNNA2,ERBB4,CNTN1,SOX5
1.108e-10	-22.92	mantle_cell_lymphoma	COSMIC cancer mutations	mantle_cell_lymphoma	2849	28	16828	48	CTNND2,NKAIN3,SLC1A2,RYR3,TNC,CPE,LRP1B,GPM6A,MAGI2,ANK2,LSAMP,PPP2R2B,PRKG1,NTRK2,NRG3,SOX5,PLCB1,PCDH9,PARD3,ADCY2,GPC5,HPSE2,CADM2,NEBL,CNTN1,ERBB4,FMN2,TRPM3
1.306e-10	-22.76	brainstem	COSMIC cancer mutations	brainstem	3102	29	16828	48	HPSE2,GPC5,FMN2,ERBB4,CADM2,PLCB1,PTPRZ1,SOX5,NRG3,PRKG1,ADCY2,NPAS3,PARD3,PCDH9,RORA,CDH20,RYR3,LSAMP,PPP2R2B,ANK2,TNIK,GPM6A,MAGI2,LRP1B,TNC,CPE,CTNND2,SLC1A2,NKAIN3
1.984e-10	-22.34	cell junction	cellular component	GO:0030054	2224	24	19108	50	NTRK2,CNTN1,SORBS1,DTNA,PTPRZ1,NRXN1,PLCB1,PARD3,GPM6A,MAGI2,TNIK,PCDH9,CTNND2,ERBB4,CADM2,CLU,APOE,NFIA,SLC1A2,TNC,ANK2,CTNNA2,CDH20,NRG3
2.158e-10	-22.26	neuron differentiation	biological process	GO:0030182	1081	18	18204	50	TNC,PTPRZ1,PARD3,APOE,NTRK2,PRKG1,NFIA,GFAP,FUT9,NTM,NRXN1,CTNND2,GPM6A,TNIK,RORA,CTNNA2,ERBB4,CNTN1
2.930e-10	-21.95	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-mantle_cell_lymphoma	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-mantle_cell_lymphoma	2737	27	16828	48	CTNND2,SLC1A2,NKAIN3,RYR3,PPP2R2B,LSAMP,ANK2,LRP1B,GPM6A,MAGI2,TNC,CPE,PLCB1,SOX5,NRG3,PRKG1,NTRK2,ADCY2,PCDH9,PARD3,HPSE2,GPC5,FMN2,ERBB4,CNTN1,NEBL,CADM2
3.320e-10	-21.83	central_nervous_system-brainstem-glioma-astrocytoma_Grade_IV	COSMIC cancer mutations	central_nervous_system-brainstem-glioma-astrocytoma_Grade_IV	2531	26	16828	48	HPSE2,GPC5,FMN2,ERBB4,CADM2,PLCB1,SOX5,PTPRZ1,NRG3,PRKG1,ADCY2,PCDH9,PARD3,RORA,RYR3,CDH20,PPP2R2B,LSAMP,TNIK,ANK2,LRP1B,MAGI2,GPM6A,CPE,CTNND2,NKAIN3
5.462e-10	-21.33	anatomical structure morphogenesis	biological process	GO:0009653	2225	24	18204	50	ERBB4,RORA,MAGI2,GPM6A,NRXN1,PRKG1,NTRK2,PARD3,NRG3,ANK2,TNC,SOX5,CNTN1,CPE,CTNNA2,CDH20,TNIK,CTNND2,NFIA,ABLIM1,NEBL,APOE,CLU,PTPRZ1
9.104e-10	-20.82	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-diffuse_large_B_cell_lymphoma	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-diffuse_large_B_cell_lymphoma	3608	30	16828	48	NRG3,PRKG1,PLCB1,SOX5,PARD3,PCDH9,ADCY2,HPSE2,GPC5,NEBL,CADM2,FMN2,CNTN1,ERBB4,CTNND2,CLU,NKAIN3,SLC1A2,RYR3,CDH20,RORA,MAGI2,GPM6A,LRP1B,TNC,CPE,PPP2R2B,LSAMP,ANK2,TNIK
9.206e-10	-20.81	MAPT (microtubule associated protein tau)	protein interactions	4137	948	16	19454	50	CTNND2,CADM2,MAPK10,ABLIM1,GPM6A,LSAMP,SLC1A2,CTNNA2,NEBL,APOE,TNIK,CLU,PPP2R2B,ANK2,SORBS1,NTM
9.527e-10	-20.77	diffuse_large_B_cell_lymphoma	COSMIC cancer mutations	diffuse_large_B_cell_lymphoma	4151	32	16828	48	RORA,CDH20,RYR3,TNIK,ANK2,PPP2R2B,LSAMP,TNC,CPE,LRP1B,MAGI2,GPM6A,CTNND2,CLU,DTNA,SLC1A2,NKAIN3,GPC5,HPSE2,CNTN1,ERBB4,FMN2,CADM2,NEBL,SOX5,PLCB1,PRKG1,NTRK2,NRG3,ADCY2,PCDH9,PARD3
1.057e-09	-20.67	prostate-carcinoma	COSMIC cancer mutations	prostate-carcinoma	9000	45	16828	48	ERBB4,TRPM3,FMN2,CADM2,PITPNC1,GPC5,ADCY2,NPAS3,PARD3,PTPRZ1,NTM,SOX5,PLCB1,NTRK2,PRKG1,GLIS3,ANK2,TNIK,LSAMP,TNC,GPM6A,LRP1B,RORA,RGS6,NKAIN3,CLU,CTNND2,DTNA,CNTN1,ABLIM1,SORBS1,NEBL,FUT9,HPSE2,PCDH9,NRG3,PPP2R2B,CPE,MAGI2,APOE,CDH20,RYR3,SLC1A2,NRXN1,NFIA
1.320e-09	-20.45	haematopoietic_and_lymphoid_tissue-haematopoietic_neoplasm-myelodysplastic_syndrome	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue-haematopoietic_neoplasm-myelodysplastic_syndrome	1174	18	16828	48	NTRK2,PRKG1,NRG3,NFIA,SOX5,PARD3,NKAIN3,ADCY2,NPAS3,SLC1A2,RYR3,HPSE2,CADM2,MAGI2,LRP1B,ERBB4,TNIK,LSAMP
1.320e-09	-20.45	myelodysplastic_syndrome	COSMIC cancer mutations	myelodysplastic_syndrome	1174	18	16828	48	PRKG1,NTRK2,NFIA,NRG3,SOX5,PARD3,NKAIN3,NPAS3,ADCY2,SLC1A2,RYR3,HPSE2,CADM2,LRP1B,MAGI2,TNIK,ERBB4,LSAMP
1.832e-09	-20.12	system development	biological process	GO:0048731	3533	29	18204	50	ANK2,PCDH9,PARD3,NRG3,TNC,NTRK2,PRKG1,SLC1A2,GPM6A,NRXN1,NTM,MAGI2,RORA,ERBB4,CLU,PTPRZ1,LSAMP,NEBL,APOE,FUT9,GFAP,NFIA,CTNND2,TNIK,PLCB1,CTNNA2,SOX5,CNTN1,CPE
4.712e-09	-19.17	cell periphery	cellular component	GO:0071944	6020	36	19108	50	PTPRZ1,TRPM3,NRXN1,CNTN1,NTRK2,SORBS1,LRP1B,DTNA,PRKG1,GPM6A,GPC5,RGS6,NTM,HPSE2,MAGI2,PARD3,FMN2,TNIK,CPE,PCDH9,CLU,CADM2,CTNND2,ERBB4,LSAMP,MAPK10,RYR3,ADCY2,NRG3,CDH20,SLC1A2,NKAIN3,APOE,ANK2,TNC,CTNNA2
5.243e-09	-19.07	multicellular organism development	biological process	GO:0007275	3957	30	18204	50	PRKG1,NTM,NRXN1,SLC1A2,GPM6A,TNC,PARD3,PCDH9,NRG3,ANK2,NTRK2,ERBB4,MAGI2,RORA,NFIA,FUT9,GFAP,CTNND2,PTPRZ1,CLU,APOE,NEBL,LSAMP,CDH20,CTNNA2,CPE,CNTN1,SOX5,TNIK,PLCB1
1.170e-08	-18.26	lymph_node	COSMIC cancer mutations	lymph_node	1703	20	16828	48	LRP1B,NEBL,MAGI2,GPM6A,TRPM3,LSAMP,TNIK,ANK2,ERBB4,RYR3,GPC5,PCDH9,PARD3,NRG3,PRKG1,DTNA,NTRK2,PLCB1,SOX5,CTNND2
1.242e-08	-18.20	plasma membrane	cellular component	GO:0005886	5538	34	19108	50	NTM,HPSE2,MAGI2,RGS6,GPM6A,GPC5,PARD3,NRXN1,TRPM3,PTPRZ1,PRKG1,SORBS1,LRP1B,DTNA,NTRK2,CNTN1,CDH20,ADCY2,RYR3,NRG3,ANK2,CTNNA2,NKAIN3,APOE,SLC1A2,CTNND2,ERBB4,CADM2,TNIK,FMN2,CPE,PCDH9,LSAMP,MAPK10
1.282e-08	-18.17	soft_tissue	COSMIC cancer mutations	soft_tissue	5828	36	16828	48	PARD3,PCDH9,ADCY2,NPAS3,NRG3,GLIS3,NTRK2,PRKG1,PLCB1,PTPRZ1,SOX5,SORBS1,NEBL,CADM2,TRPM3,FMN2,ERBB4,HPSE2,GPC5,NKAIN3,SLC1A2,NFIA,CTNND2,CLU,GPM6A,APOE,MAGI2,LRP1B,TNC,PPP2R2B,LSAMP,ANK2,RYR3,RGS6,CDH20,RORA
1.514e-08	-18.01	cell junction organization	biological process	GO:0034330	532	12	18204	50	APOE,TNC,PARD3,NRG3,ANK2,NRXN1,CTNND2,SORBS1,GPM6A,NFIA,CDH20,ERBB4
1.568e-08	-17.97	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-chronic_lymphocytic_leukaemia-small_lymphocytic_lymphoma	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-chronic_lymphocytic_leukaemia-small_lymphocytic_lymphoma	3511	28	16828	48	GPC5,FUT9,HPSE2,ERBB4,FMN2,TRPM3,CADM2,PITPNC1,PTPRZ1,PLCB1,MGAT4C,PRKG1,NTRK2,NRG3,NPAS3,ADCY2,PCDH9,PARD3,RYR3,TNIK,LSAMP,PPP2R2B,CPE,LRP1B,MAGI2,CLU,CTNND2,DTNA
1.568e-08	-17.97	chronic_lymphocytic_leukaemia-small_lymphocytic_lymphoma	COSMIC cancer mutations	chronic_lymphocytic_leukaemia-small_lymphocytic_lymphoma	3511	28	16828	48	GPC5,HPSE2,FUT9,ERBB4,TRPM3,FMN2,CADM2,PITPNC1,PTPRZ1,MGAT4C,PLCB1,NTRK2,PRKG1,NRG3,ADCY2,NPAS3,PARD3,PCDH9,RYR3,TNIK,LSAMP,PPP2R2B,CPE,MAGI2,LRP1B,CTNND2,CLU,DTNA
3.756e-08	-17.10	right_upper_lobe	COSMIC cancer mutations	right_upper_lobe	10376	46	16828	48	PCDH9,MGAT4C,NRG3,CNTN1,ABLIM1,SORBS1,NEBL,HPSE2,FUT9,SLC1A2,NRXN1,NFIA,PPP2R2B,APOE,MAGI2,CPE,CDH20,RYR3,ADCY2,NPAS3,PARD3,PLCB1,PTPRZ1,NTM,SOX5,GLIS3,NTRK2,PRKG1,TRPM3,FMN2,ERBB4,PITPNC1,CADM2,GPC5,NKAIN3,CTNND2,DTNA,LSAMP,ANK2,TNIK,GPM6A,LRP1B,TNC,RORA,GFAP,RGS6
3.756e-08	-17.10	lung-right_upper_lobe-carcinoma-adenocarcinoma	COSMIC cancer mutations	lung-right_upper_lobe-carcinoma-adenocarcinoma	10376	46	16828	48	RYR3,CDH20,PPP2R2B,MAGI2,APOE,CPE,NFIA,SLC1A2,NRXN1,HPSE2,FUT9,CNTN1,ABLIM1,SORBS1,NEBL,MGAT4C,NRG3,PCDH9,RORA,GFAP,RGS6,LSAMP,ANK2,TNIK,GPM6A,LRP1B,TNC,CTNND2,DTNA,NKAIN3,GPC5,TRPM3,FMN2,ERBB4,PITPNC1,CADM2,PLCB1,PTPRZ1,SOX5,NTM,GLIS3,NTRK2,PRKG1,ADCY2,NPAS3,PARD3
3.804e-08	-17.08	central_nervous_system-brain-primitive_neuroectodermal_tumour-medulloblastoma-large_cell	COSMIC cancer mutations	central_nervous_system-brain-primitive_neuroectodermal_tumour-medulloblastoma-large_cell	1117	16	16828	48	PARD3,SLC1A2,ADCY2,NRG3,PRKG1,PLCB1,SOX5,MAGI2,LRP1B,FMN2,ERBB4,ANK2,CDH20,RYR3,RGS6,GPC5
4.684e-08	-16.88	neuron development	biological process	GO:0048666	859	14	18204	50	CNTN1,CTNNA2,TNIK,CTNND2,NTM,NRXN1,GPM6A,PRKG1,GFAP,APOE,NTRK2,PTPRZ1,TNC,PARD3
4.877e-08	-16.84	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-follicular_lymphoma	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-follicular_lymphoma	981	15	16828	48	MAGI2,LRP1B,CADM2,LSAMP,RORA,HPSE2,GPC5,NKAIN3,PARD3,PCDH9,ADCY2,NRG3,PRKG1,CTNND2,SOX5
5.405e-08	-16.73	central_nervous_system-brain-primitive_neuroectodermal_tumour-medulloblastoma	COSMIC cancer mutations	central_nervous_system-brain-primitive_neuroectodermal_tumour-medulloblastoma	7205	39	16828	48	PARD3,PCDH9,ADCY2,NPAS3,NTRK2,PRKG1,NRG3,GLIS3,PTPRZ1,NTM,SOX5,PLCB1,CADM2,PITPNC1,SORBS1,NEBL,CNTN1,ERBB4,ABLIM1,TRPM3,FMN2,GPC5,HPSE2,NKAIN3,NRXN1,SLC1A2,NFIA,CTNND2,CPE,GPM6A,MAGI2,LRP1B,ANK2,TNIK,LSAMP,PPP2R2B,RGS6,RYR3,RORA
9.276e-08	-16.19	synapse	cellular component	GO:0045202	1473	17	19108	50	SLC1A2,PLCB1,APOE,ANK2,NRG3,GPM6A,MAGI2,CNTN1,NTRK2,DTNA,TNIK,PTPRZ1,CLU,CADM2,CTNND2,ERBB4,NRXN1
1.060e-07	-16.06	trunk	COSMIC cancer mutations	trunk	3554	27	16828	48	HPSE2,ERBB4,ABLIM1,NEBL,CADM2,MGAT4C,PLCB1,PTPRZ1,SOX5,NRG3,GLIS3,NTRK2,NPAS3,PARD3,PCDH9,CDH20,RYR3,RGS6,LSAMP,PPP2R2B,ANK2,MAGI2,LRP1B,TNC,CPE,CTNND2,NRXN1
1.143e-07	-15.98	follicular_lymphoma	COSMIC cancer mutations	follicular_lymphoma	1209	16	16828	48	CADM2,MAGI2,LRP1B,TNIK,LSAMP,GPC5,RORA,HPSE2,PARD3,PCDH9,NKAIN3,ADCY2,PRKG1,NRG3,CTNND2,SOX5
1.308e-07	-15.85	cell development	biological process	GO:0048468	2236	21	18204	50	RORA,MAGI2,FMN2,TNIK,CNTN1,CTNNA2,ERBB4,APOE,NTRK2,NEBL,CLU,TNC,PTPRZ1,ANK2,PARD3,NTM,NRXN1,CTNND2,GPM6A,PRKG1,GFAP
1.436e-07	-15.76	neuron projection	cellular component	GO:0043005	1331	16	19108	50	ADCY2,GPM6A,RGS6,MAGI2,SLC1A2,APOE,CTNNA2,PARD3,ANK2,PCDH9,CADM2,CLU,CTNND2,CNTN1,NTRK2,DTNA
1.512e-07	-15.70	bone-humerus-other-chondroblastoma	COSMIC cancer mutations	bone-humerus-other-chondroblastoma	301	9	16828	48	GPC5,SOX5,PRKG1,PPP2R2B,FMN2,ADCY2,NKAIN3,GPM6A,LRP1B
1.762e-07	-15.55	lung-right_lower_lobe-carcinoma-adenocarcinoma	COSMIC cancer mutations	lung-right_lower_lobe-carcinoma-adenocarcinoma	5692	34	16828	48	GPC5,FUT9,HPSE2,NEBL,SORBS1,CNTN1,ERBB4,FMN2,TRPM3,PRKG1,NTRK2,NRG3,NTM,SOX5,PTPRZ1,PLCB1,MGAT4C,PARD3,NPAS3,ADCY2,CDH20,RGS6,RYR3,TNC,LRP1B,MAGI2,GPM6A,ANK2,LSAMP,PPP2R2B,DTNA,CLU,CTNND2,NKAIN3
1.762e-07	-15.55	right_lower_lobe	COSMIC cancer mutations	right_lower_lobe	5692	34	16828	48	LSAMP,PPP2R2B,ANK2,GPM6A,MAGI2,LRP1B,TNC,RYR3,CDH20,RGS6,NKAIN3,CTNND2,CLU,DTNA,TRPM3,FMN2,ERBB4,CNTN1,SORBS1,NEBL,HPSE2,FUT9,GPC5,ADCY2,NPAS3,PARD3,MGAT4C,PLCB1,PTPRZ1,SOX5,NTM,NRG3,NTRK2,PRKG1
1.895e-07	-15.48	mucosal	COSMIC cancer mutations	mucosal	2009	20	16828	48	CTNND2,PLCB1,MGAT4C,NRG3,PCDH9,PARD3,RORA,RGS6,ABLIM1,ANK2,ERBB4,FMN2,PPP2R2B,CADM2,TNC,CPE,LRP1B,NEBL,SORBS1,MAGI2
1.895e-07	-15.48	skin-mucosal-malignant_melanoma	COSMIC cancer mutations	skin-mucosal-malignant_melanoma	2009	20	16828	48	LRP1B,NEBL,MAGI2,SORBS1,TNC,CPE,CADM2,FMN2,PPP2R2B,ABLIM1,ERBB4,ANK2,RGS6,RORA,PCDH9,PARD3,NRG3,PLCB1,MGAT4C,CTNND2
2.064e-07	-15.39	anatomical structure development	biological process	GO:0048856	5207	32	18204	50	ERBB4,RORA,MAGI2,FMN2,NRXN1,NTM,SLC1A2,GPM6A,PRKG1,NTRK2,TNC,NRG3,PCDH9,PARD3,ANK2,CNTN1,CPE,SOX5,CDH20,CTNNA2,PLCB1,TNIK,CTNND2,ABLIM1,NFIA,GFAP,FUT9,APOE,LSAMP,NEBL,CLU,PTPRZ1
2.083e-07	-15.38	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-plasma_cell_myeloma	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-plasma_cell_myeloma	1263	16	16828	48	RYR3,HPSE2,FUT9,LRP1B,NEBL,GPM6A,TNC,FMN2,ABLIM1,TNIK,ANK2,NRG3,NTRK2,CTNND2,NTM,ADCY2
2.083e-07	-15.38	plasma_cell_myeloma	COSMIC cancer mutations	plasma_cell_myeloma	1263	16	16828	48	FUT9,HPSE2,RYR3,ABLIM1,TNIK,ANK2,FMN2,TNC,NEBL,LRP1B,GPM6A,CTNND2,NTM,NTRK2,NRG3,ADCY2
2.363e-07	-15.26	skin-face-carcinoma-squamous_cell_carcinoma	COSMIC cancer mutations	skin-face-carcinoma-squamous_cell_carcinoma	2036	20	16828	48	PCDH9,PARD3,PTPRZ1,RBMS3,PLCB1,NRG3,ABLIM1,ANK2,ERBB4,FMN2,LSAMP,TRPM3,PPP2R2B,NEBL,LRP1B,MAGI2,GPM6A,GPC5,RORA,GFAP
2.466e-07	-15.22	cell morphogenesis	biological process	GO:0000902	687	12	18204	50	TNIK,CNTN1,CTNNA2,CDH20,PARD3,PTPRZ1,CLU,GPM6A,CTNND2,NRXN1,NFIA,PRKG1
2.707e-07	-15.12	neuron projection development	biological process	GO:0031175	693	12	18204	50	CNTN1,CTNNA2,TNIK,NRXN1,CTNND2,GPM6A,PRKG1,GFAP,APOE,TNC,PTPRZ1,PARD3
3.366e-07	-14.90	bone-tibia-other-chondroblastoma	COSMIC cancer mutations	bone-tibia-other-chondroblastoma	98	6	16828	48	PLCB1,CTNND2,LSAMP,LRP1B,GPM6A,NKAIN3
4.244e-07	-14.67	scalp	COSMIC cancer mutations	scalp	2110	20	16828	48	FMN2,LSAMP,PPP2R2B,ANK2,CNTN1,ERBB4,NEBL,SORBS1,TNC,RORA,GPC5,GFAP,NRXN1,RBMS3,PLCB1,NTM,SOX5,PTPRZ1,NFIA,PRKG1
4.508e-07	-14.61	mast_cell_neoplasm	COSMIC cancer mutations	mast_cell_neoplasm	248	8	16828	48	GPC5,HPSE2,NRG3,NFIA,ADCY2,ERBB4,NPAS3,PCDH9
4.508e-07	-14.61	haematopoietic_and_lymphoid_tissue-haematopoietic_neoplasm-mast_cell_neoplasm	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue-haematopoietic_neoplasm-mast_cell_neoplasm	248	8	16828	48	ADCY2,ERBB4,NPAS3,GPC5,HPSE2,PCDH9,NRG3,NFIA
4.845e-07	-14.54	upper_aerodigestive_tract-mouth-carcinoma-squamous_cell_carcinoma	COSMIC cancer mutations	upper_aerodigestive_tract-mouth-carcinoma-squamous_cell_carcinoma	6953	37	16828	48	ADCY2,PCDH9,PARD3,SOX5,NTM,PTPRZ1,PLCB1,MGAT4C,PRKG1,NRG3,ABLIM1,ERBB4,CNTN1,FMN2,TRPM3,NEBL,SORBS1,PITPNC1,GPC5,FUT9,SLC1A2,NRXN1,CTNND2,DTNA,TNIK,ANK2,LSAMP,PPP2R2B,TNC,LRP1B,GPM6A,MAGI2,RORA,CDH20,RYR3,RGS6,GFAP
5.069e-07	-14.49	central_nervous_system-cerebellum-glioma-astrocytoma_Grade_I	COSMIC cancer mutations	central_nervous_system-cerebellum-glioma-astrocytoma_Grade_I	105	6	16828	48	PRKG1,NRG3,GPC5,PARD3,MAGI2,LRP1B
5.280e-07	-14.45	PRNP (prion protein (Kanno blood group))	protein interactions	5621	1118	14	19454	50	CPE,ABLIM1,CNTN1,TRPM3,GPM6A,LSAMP,PLCB1,PTPRZ1,APOE,CLU,ANK2,SORBS1,TNC,MAGI2
5.302e-07	-14.45	face	COSMIC cancer mutations	face	2139	20	16828	48	LRP1B,NEBL,GPM6A,MAGI2,ABLIM1,ANK2,ERBB4,FMN2,LSAMP,PPP2R2B,TRPM3,GFAP,GPC5,RORA,PCDH9,PARD3,NRG3,PTPRZ1,RBMS3,PLCB1
5.571e-07	-14.40	mouth	COSMIC cancer mutations	mouth	9004	42	16828	48	CTNND2,CLU,DTNA,SLC1A2,NRXN1,RORA,GFAP,RGS6,RYR3,CDH20,LSAMP,PPP2R2B,ANK2,TNIK,GPM6A,APOE,MAGI2,LRP1B,TNC,MGAT4C,PLCB1,PTPRZ1,SOX5,NTM,NRG3,NTRK2,PRKG1,ADCY2,NPAS3,PARD3,PCDH9,HPSE2,FUT9,GPC5,TRPM3,FMN2,ERBB4,CNTN1,ABLIM1,PITPNC1,SORBS1,NEBL
7.662e-07	-14.08	adenoma	COSMIC cancer mutations	adenoma	2873	23	16828	48	TNC,LRP1B,APOE,GPM6A,MAGI2,RGS6,CDH20,RYR3,CTNND2,CADM2,NEBL,ERBB4,TRPM3,GPC5,HPSE2,PCDH9,PARD3,NPAS3,ADCY2,PRKG1,NTRK2,SOX5,PTPRZ1
8.204e-07	-14.01	skin-trunk-malignant_melanoma	COSMIC cancer mutations	skin-trunk-malignant_melanoma	2647	22	16828	48	NRG3,MGAT4C,PLCB1,PTPRZ1,SOX5,CTNND2,NRXN1,PARD3,PCDH9,CDH20,RGS6,RYR3,HPSE2,MAGI2,LRP1B,NEBL,CADM2,TNC,PPP2R2B,LSAMP,ERBB4,ANK2
8.489e-07	-13.98	membrane	cellular component	GO:0016020	9220	41	19108	50	PARD3,PLCB1,RGS6,HPSE2,MAGI2,NTM,GPC5,GPM6A,DTNA,LRP1B,SORBS1,PRKG1,CNTN1,PPP2R2B,NTRK2,TRPM3,NRXN1,PTPRZ1,CTNNA2,GFAP,TNC,ANK2,MGAT4C,FUT9,SLC1A2,APOE,NKAIN3,NRG3,ADCY2,RYR3,CDH20,MAPK10,LSAMP,CLU,CADM2,CTNND2,ERBB4,PCDH9,TNIK,FMN2,CPE
9.499e-07	-13.87	cell projection	cellular component	GO:0042995	2398	20	19108	50	MAGI2,RGS6,ADCY2,GPM6A,CTNNA2,PARD3,ANK2,GFAP,APOE,SLC1A2,CTNND2,NRXN1,CADM2,CLU,PCDH9,FMN2,DTNA,NTRK2,ABLIM1,CNTN1
9.933e-07	-13.82	cell junction assembly	biological process	GO:0034329	285	8	18204	50	PARD3,NRG3,ANK2,SORBS1,GPM6A,NRXN1,ERBB4,CDH20
1.183e-06	-13.65	NUFIP1 (nuclear FMR1 interacting protein 1)	protein interactions	26747	134	6	19454	50	CADM2,CPE,GPM6A,ANK2,CNTN1,NTM
1.570e-06	-13.36	Htt (huntingtin)	protein interactions	15194	77	5	19454	50	GFAP,CNTN1,GPM6A,NTM,LSAMP
1.755e-06	-13.25	skin-extremity-malignant_melanoma	COSMIC cancer mutations	skin-extremity-malignant_melanoma	1875	18	16828	48	NTRK2,PLCB1,PTPRZ1,PCDH9,PARD3,ADCY2,CDH20,RYR3,HPSE2,FUT9,NEBL,LRP1B,PITPNC1,TNC,CADM2,FMN2,ANK2,ERBB4
1.768e-06	-13.25	extremity	COSMIC cancer mutations	extremity	1876	18	16828	48	ADCY2,PARD3,PCDH9,PTPRZ1,PLCB1,NTRK2,ERBB4,ANK2,FMN2,TNC,CADM2,PITPNC1,NEBL,LRP1B,FUT9,HPSE2,CDH20,RYR3
1.926e-06	-13.16	central nervous system development	biological process	GO:0007417	995	13	18204	50	CTNNA2,ERBB4,CNTN1,PLCB1,RORA,GFAP,PRKG1,SLC1A2,PCDH9,NRG3,PTPRZ1,CLU,NTRK2
2.063e-06	-13.09	cell differentiation	biological process	GO:0030154	3645	25	18204	50	ERBB4,RORA,MAGI2,FMN2,GPM6A,NTM,NRXN1,PRKG1,NTRK2,ANK2,PARD3,TNC,SOX5,CNTN1,CTNNA2,PLCB1,TNIK,CTNND2,FUT9,GFAP,NFIA,NEBL,APOE,CLU,PTPRZ1
2.083e-06	-13.08	developmental process	biological process	GO:0032502	5716	32	18204	50	PLCB1,TNIK,SOX5,CNTN1,CPE,CTNNA2,CDH20,LSAMP,NEBL,APOE,CLU,PTPRZ1,CTNND2,GFAP,FUT9,ABLIM1,NFIA,RORA,MAGI2,FMN2,ERBB4,NTRK2,PCDH9,PARD3,NRG3,ANK2,TNC,GPM6A,SLC1A2,NTM,NRXN1,PRKG1
2.096e-06	-13.08	cellular developmental process	biological process	GO:0048869	3648	25	18204	50	CNTN1,SOX5,CTNNA2,PLCB1,TNIK,CTNND2,NFIA,GFAP,FUT9,APOE,NEBL,PTPRZ1,CLU,ERBB4,RORA,FMN2,MAGI2,NTM,NRXN1,GPM6A,PRKG1,NTRK2,TNC,ANK2,PARD3
2.123e-06	-13.06	plasma membrane bounded cell projection	cellular component	GO:0120025	2285	19	19108	50	GFAP,PARD3,ANK2,CTNNA2,SLC1A2,APOE,RGS6,MAGI2,ADCY2,GPM6A,DTNA,CNTN1,ABLIM1,NTRK2,CADM2,CLU,CTNND2,FMN2,PCDH9
2.133e-06	-13.06	glial cell differentiation	biological process	GO:0010001	219	7	18204	50	NTRK2,PARD3,CLU,PTPRZ1,CNTN1,GFAP,NFIA
2.396e-06	-12.94	nodular	COSMIC cancer mutations	nodular	1515	16	16828	48	NPAS3,NTRK2,GLIS3,PTPRZ1,CTNND2,PLCB1,CPE,MAGI2,LRP1B,NEBL,ERBB4,CNTN1,ABLIM1,FMN2,CDH20,RGS6
2.565e-06	-12.87	humerus	COSMIC cancer mutations	humerus	546	10	16828	48	NKAIN3,GPM6A,NEBL,LRP1B,PPP2R2B,FMN2,ADCY2,PRKG1,SOX5,GPC5
2.630e-06	-12.85	astrocytoma_Grade_I	COSMIC cancer mutations	astrocytoma_Grade_I	139	6	16828	48	GPC5,PARD3,PRKG1,MAGI2,NRG3,LRP1B
3.170e-06	-12.66	synapse organization	biological process	GO:0050808	333	8	18204	50	TNC,NRG3,APOE,NFIA,ERBB4,CTNND2,NRXN1,GPM6A
3.587e-06	-12.54	multicellular organismal process	biological process	GO:0032501	6177	33	18204	50	NRXN1,NTM,SLC1A2,GPM6A,PRKG1,NTRK2,RYR3,TNC,PCDH9,PARD3,NRG3,ANK2,ERBB4,RORA,DTNA,MAGI2,CTNND2,ABLIM1,NFIA,FUT9,GFAP,APOE,NEBL,LSAMP,PTPRZ1,CLU,CPE,CNTN1,SOX5,CDH20,CTNNA2,PLCB1,TNIK
4.460e-06	-12.32	upper_aerodigestive_tract-mouth-carcinoma	COSMIC cancer mutations	upper_aerodigestive_tract-mouth-carcinoma	6426	34	16828	48	PARD3,ADCY2,NPAS3,NRG3,PRKG1,MGAT4C,PLCB1,SOX5,NTM,SORBS1,PITPNC1,TRPM3,FMN2,ERBB4,CNTN1,ABLIM1,HPSE2,FUT9,GPC5,SLC1A2,CLU,CTNND2,MAGI2,APOE,GPM6A,LRP1B,TNC,PPP2R2B,ANK2,GFAP,RYR3,RGS6,CDH20,RORA
5.074e-06	-12.19	oesophagus-carcinoma	COSMIC cancer mutations	oesophagus-carcinoma	4269	27	16828	48	PPP2R2B,TNIK,ANK2,LRP1B,GPM6A,MAGI2,CDH20,RGS6,RYR3,CTNND2,NFIA,FMN2,TRPM3,CNTN1,SORBS1,CADM2,HPSE2,ADCY2,PCDH9,PARD3,PLCB1,SOX5,NTM,PTPRZ1,NRG3,PRKG1,NTRK2
5.447e-06	-12.12	central_nervous_system-brain-glioma-astrocytoma_Grade_III	COSMIC cancer mutations	central_nervous_system-brain-glioma-astrocytoma_Grade_III	1419	15	16828	48	ADCY2,PARD3,PLCB1,NRG3,PRKG1,TRPM3,ANK2,ERBB4,MAGI2,LRP1B,CADM2,HPSE2,FUT9,GPC5,RYR3
6.057e-06	-12.01	neuron projection morphogenesis	biological process	GO:0048812	486	9	18204	50	PTPRZ1,TNIK,PARD3,CNTN1,NRXN1,CTNND2,GPM6A,PRKG1,CTNNA2
6.347e-06	-11.97	CNTN1 (contactin 1)	protein interactions	1272	47	4	19454	50	CNTN1,GPM6A,TNC,PTPRZ1
6.578e-06	-11.93	plasma membrane bounded cell projection morphogenesis	biological process	GO:0120039	491	9	18204	50	CTNNA2,PRKG1,GPM6A,NRXN1,CNTN1,CTNND2,PARD3,TNIK,PTPRZ1
6.732e-06	-11.91	cell adhesion	biological process	GO:0007155	942	12	18204	50	LSAMP,PARD3,PCDH9,TNC,SORBS1,CTNND2,CNTN1,NRXN1,CADM2,NTM,CTNNA2,CDH20
7.138e-06	-11.85	cell projection morphogenesis	biological process	GO:0048858	496	9	18204	50	CTNND2,CNTN1,NRXN1,GPM6A,PRKG1,CTNNA2,TNIK,PTPRZ1,PARD3
9.536e-06	-11.56	gliogenesis	biological process	GO:0042063	275	7	18204	50	CNTN1,GFAP,NFIA,NTRK2,PARD3,CLU,PTPRZ1
9.591e-06	-11.55	plasma membrane bounded cell projection organization	biological process	GO:0120036	1152	13	18204	50	PRKG1,ABLIM1,GFAP,NRXN1,CTNND2,GPM6A,TNC,PTPRZ1,PARD3,APOE,CTNNA2,CNTN1,TNIK
9.613e-06	-11.55	skin-scalp-malignant_melanoma	COSMIC cancer mutations	skin-scalp-malignant_melanoma	634	10	16828	48	PTPRZ1,NTM,PLCB1,NFIA,ERBB4,PPP2R2B,FMN2,TNC,SORBS1,NEBL
1.111e-05	-11.41	SYNM (synemin)	protein interactions	23336	54	4	19454	50	DTNA,ERBB4,PPP2R2B,GFAP
1.376e-05	-11.19	upper_aerodigestive_tract-larynx-carcinoma-squamous_cell_carcinoma	COSMIC cancer mutations	upper_aerodigestive_tract-larynx-carcinoma-squamous_cell_carcinoma	1946	17	16828	48	HPSE2,RORA,RYR3,FMN2,TNIK,CNTN1,ERBB4,NEBL,LRP1B,GPM6A,PLCB1,RBMS3,MGAT4C,SOX5,NPAS3,NRXN1,PCDH9
1.395e-05	-11.18	larynx	COSMIC cancer mutations	larynx	1948	17	16828	48	RYR3,RORA,HPSE2,GPM6A,NEBL,LRP1B,CNTN1,ERBB4,TNIK,FMN2,SOX5,MGAT4C,RBMS3,PLCB1,PCDH9,NRXN1,NPAS3
1.395e-05	-11.18	cell adhesion molecule binding	molecular function	GO:0050839	560	9	18094	48	CTNND2,CTNNA2,GFAP,TNC,NRXN1,CNTN1,PTPRZ1,CPE,CDH20
1.487e-05	-11.12	cell projection organization	biological process	GO:0030030	1200	13	18204	50	CTNNA2,CNTN1,TNIK,GFAP,PRKG1,ABLIM1,GPM6A,NRXN1,CTNND2,PARD3,TNC,PTPRZ1,APOE
1.518e-05	-11.10	astrocytoma_Grade_III	COSMIC cancer mutations	astrocytoma_Grade_III	1544	15	16828	48	RYR3,GPC5,FUT9,HPSE2,CADM2,LRP1B,MAGI2,ANK2,ERBB4,TRPM3,PRKG1,NRG3,PLCB1,PARD3,ADCY2
1.776e-05	-10.94	tibia	COSMIC cancer mutations	tibia	836	11	16828	48	PRKG1,CTNND2,PLCB1,CPE,LRP1B,NKAIN3,GPM6A,ABLIM1,TNIK,LSAMP,TRPM3
1.836e-05	-10.91	CTNNA1 (catenin alpha 1)	protein interactions	1495	325	7	19454	50	CTNNA2,SORBS1,DTNA,PARD3,ABLIM1,NEBL,TNIK
2.014e-05	-10.81	pharynx	COSMIC cancer mutations	pharynx	2696	20	16828	48	PCDH9,SLC1A2,NPAS3,NRG3,NFIA,NTRK2,DTNA,PTPRZ1,CTNND2,CLU,PITPNC1,SORBS1,MAGI2,LRP1B,CADM2,FMN2,ANK2,RYR3,FUT9,GPC5
2.258e-05	-10.70	brain development	biological process	GO:0007420	724	10	18204	50	SLC1A2,CNTN1,CTNNA2,ERBB4,PRKG1,NTRK2,RORA,PLCB1,NRG3,PCDH9
2.334e-05	-10.67	lung-left_upper_lobe-carcinoma-adenocarcinoma	COSMIC cancer mutations	lung-left_upper_lobe-carcinoma-adenocarcinoma	556	9	16828	48	CTNND2,PLCB1,PRKG1,NTRK2,RYR3,RGS6,ADCY2,ERBB4,LRP1B
2.401e-05	-10.64	left_upper_lobe	COSMIC cancer mutations	left_upper_lobe	558	9	16828	48	RGS6,RYR3,PRKG1,NTRK2,PLCB1,CTNND2,LRP1B,ADCY2,ERBB4
2.463e-05	-10.61	NTRK2 (neurotrophic receptor tyrosine kinase 2)	protein interactions	4915	135	5	19454	50	NTRK2,ABLIM1,DTNA,PARD3,ERBB4
2.529e-05	-10.59	regulation of neuron projection development	biological process	GO:0010975	443	8	18204	50	NTRK2,APOE,TNIK,MAGI2,CNTN1,GFAP,CTNNA2,FUT9
2.613e-05	-10.55	glial cell development	biological process	GO:0021782	128	5	18204	50	CLU,GFAP,PARD3,CNTN1,NTRK2
2.613e-05	-10.55	myelination	biological process	GO:0042552	128	5	18204	50	NTRK2,CNTN1,PARD3,ANK2,CLU
2.815e-05	-10.48	ensheathment of neurons	biological process	GO:0007272	130	5	18204	50	NTRK2,CNTN1,ANK2,PARD3,CLU
2.815e-05	-10.48	axon ensheathment	biological process	GO:0008366	130	5	18204	50	PARD3,ANK2,CLU,NTRK2,CNTN1
3.268e-05	-10.33	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm	7307	35	16828	48	PCDH9,PARD3,ADCY2,GLIS3,NRG3,PRKG1,NTRK2,PLCB1,MGAT4C,SOX5,PTPRZ1,NEBL,CADM2,FMN2,ABLIM1,CNTN1,ERBB4,HPSE2,GPC5,NKAIN3,SLC1A2,CLU,CTNND2,LRP1B,MAGI2,GPM6A,CPE,TNC,PPP2R2B,LSAMP,TNIK,ANK2,CDH20,RYR3,RORA
3.411e-05	-10.29	protein localization to membrane	biological process	GO:0072657	462	8	18204	50	ANK2,PARD3,TNIK,MAGI2,APOE,ERBB4,CPE,NRXN1
3.935e-05	-10.14	lymphoid_neoplasm	COSMIC cancer mutations	lymphoid_neoplasm	12233	46	16828	48	PCDH9,MGAT4C,NRG3,CNTN1,ABLIM1,SORBS1,NEBL,HPSE2,FUT9,SLC1A2,NRXN1,NFIA,PPP2R2B,MAGI2,CPE,RYR3,CDH20,ADCY2,NPAS3,PARD3,PLCB1,PTPRZ1,SOX5,NTM,GLIS3,NTRK2,PRKG1,TRPM3,FMN2,ERBB4,PITPNC1,CADM2,GPC5,NKAIN3,CTNND2,CLU,DTNA,LSAMP,ANK2,TNIK,GPM6A,LRP1B,TNC,RORA,GFAP,RGS6
3.954e-05	-10.14	postsynapse	cellular component	GO:0098794	646	9	19108	50	TNIK,GPM6A,ERBB4,CTNND2,MAGI2,CNTN1,PLCB1,NTRK2,ANK2
3.991e-05	-10.13	head development	biological process	GO:0060322	774	10	18204	50	SLC1A2,CNTN1,CTNNA2,ERBB4,PRKG1,NTRK2,PLCB1,RORA,NRG3,PCDH9
3.994e-05	-10.13	haematopoietic_and_lymphoid_tissue-lymph_node-lymphoid_neoplasm-diffuse_large_B_cell_lymphoma	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue-lymph_node-lymphoid_neoplasm-diffuse_large_B_cell_lymphoma	748	10	16828	48	LRP1B,NEBL,PARD3,ANK2,PRKG1,DTNA,NTRK2,PLCB1,SOX5,CTNND2
4.148e-05	-10.09	axon	cellular component	GO:0030424	650	9	19108	50	CNTN1,SLC1A2,NTRK2,PARD3,DTNA,CTNNA2,GPM6A,PCDH9,CADM2
4.286e-05	-10.06	carcinoid-endocrine_tumour	COSMIC cancer mutations	carcinoid-endocrine_tumour	7752	36	16828	48	GPC5,HPSE2,CADM2,NEBL,ABLIM1,ERBB4,CNTN1,FMN2,TRPM3,PRKG1,NTRK2,GLIS3,NRG3,SOX5,PTPRZ1,PLCB1,PCDH9,PARD3,ADCY2,RYR3,CDH20,RORA,CPE,TNC,LRP1B,GPM6A,MAGI2,APOE,TNIK,ANK2,PPP2R2B,LSAMP,CLU,CTNND2,NKAIN3,SLC1A2
4.567e-05	-9.99	skin-trunk-malignant_melanoma-nodular	COSMIC cancer mutations	skin-trunk-malignant_melanoma-nodular	1291	13	16828	48	NPAS3,GLIS3,NTRK2,PLCB1,CTNND2,PTPRZ1,LRP1B,NEBL,CPE,ABLIM1,ERBB4,CDH20,RGS6
4.839e-05	-9.94	superficial_spreading	COSMIC cancer mutations	superficial_spreading	1110	12	16828	48	SORBS1,LRP1B,TNC,PPP2R2B,ERBB4,FUT9,ADCY2,PRKG1,MGAT4C,PLCB1,NTM,CTNND2
5.088e-05	-9.89	cell-cell junction	cellular component	GO:0005911	513	8	19108	50	ANK2,SORBS1,PARD3,CTNNA2,CDH20,PCDH9,MAGI2,CTNND2
5.463e-05	-9.81	cellular component assembly	biological process	GO:0022607	2472	18	18204	50	TNIK,FMN2,CNTN1,ERBB4,CDH20,NEBL,TRPM3,APOE,PARD3,ANK2,NRG3,CLU,RYR3,SLC1A2,SORBS1,GPM6A,NRXN1,ABLIM1
5.838e-05	-9.75	signaling	biological process	GO:0023052	4968	27	18204	50	NTRK2,ADCY2,RYR3,TNC,ANK2,NRG3,PARD3,NRXN1,SORBS1,SLC1A2,PRKG1,RORA,MAPK10,FMN2,DTNA,MAGI2,ERBB4,APOE,PITPNC1,CLU,CTNND2,NFIA,PLCB1,TNIK,CPE,RGS6,CNTN1
6.014e-05	-9.72	NS-malignant_melanoma	COSMIC cancer mutations	NS-malignant_melanoma	3420	22	16828	48	GLIS3,NRG3,PTPRZ1,PLCB1,MGAT4C,PCDH9,PARD3,ADCY2,GPC5,FUT9,CADM2,NEBL,PITPNC1,ERBB4,FMN2,TRPM3,CTNND2,NRXN1,TNC,LRP1B,MAGI2,ANK2
6.085e-05	-9.71	glial cell proliferation	biological process	GO:0014009	28	3	18204	50	GFAP,NFIA,CLU
6.597e-05	-9.63	Nuclear signaling by ERBB4	REACTOME pathways	R-HSA-1251985	25	3	10285	33	GFAP,ERBB4,NRG3
6.775e-05	-9.60	negative regulation of amyloid-beta formation	biological process	GO:1902430	29	3	18204	50	CLU,NTRK2,APOE
6.848e-05	-9.59	cell communication	biological process	GO:0007154	5010	27	18204	50	ERBB4,MAPK10,RORA,DTNA,MAGI2,FMN2,SORBS1,SLC1A2,NRXN1,PRKG1,ADCY2,NTRK2,NRG3,ANK2,PARD3,TNC,RYR3,CNTN1,RGS6,CPE,PLCB1,TNIK,CTNND2,NFIA,PITPNC1,APOE,CLU
7.268e-05	-9.53	regulation of plasma membrane bounded cell projection organization	biological process	GO:0120035	666	9	18204	50	GPM6A,CNTN1,CTNNA2,FUT9,GFAP,NTRK2,APOE,MAGI2,TNIK
7.270e-05	-9.53	oesophagus-carcinoma-squamous_cell_carcinoma	COSMIC cancer mutations	oesophagus-carcinoma-squamous_cell_carcinoma	6486	32	16828	48	NRXN1,CTNND2,LRP1B,GPM6A,MAGI2,CPE,TNC,TNIK,ANK2,RYR3,PCDH9,PARD3,NPAS3,ADCY2,GLIS3,NRG3,PRKG1,PLCB1,MGAT4C,SOX5,PTPRZ1,NEBL,PITPNC1,SORBS1,CADM2,FMN2,TRPM3,ABLIM1,ERBB4,CNTN1,HPSE2,GPC5
7.355e-05	-9.52	D-aspartate transmembrane transport	biological process	GO:0070777	5	2	18204	50	GFAP,SLC1A2
7.355e-05	-9.52	positive regulation of amyloid fibril formation	biological process	GO:1905908	5	2	18204	50	CLU,APOE
7.355e-05	-9.52	D-aspartate import across plasma membrane	biological process	GO:0070779	5	2	18204	50	SLC1A2,GFAP
7.616e-05	-9.48	presynaptic membrane	cellular component	GO:0042734	168	5	19108	50	GPM6A,SLC1A2,CNTN1,NRXN1,ERBB4
7.812e-05	-9.46	positive regulation of neuron projection development	biological process	GO:0010976	161	5	18204	50	FUT9,MAGI2,NTRK2,APOE,CNTN1
8.255e-05	-9.40	NTM (neurotrimin)	protein interactions	50863	33	3	19454	50	GPM6A,LSAMP,NTM
8.302e-05	-9.40	negative regulation of amyloid precursor protein catabolic process	biological process	GO:1902992	31	3	18204	50	CLU,NTRK2,APOE
8.655e-05	-9.35	oligodendrocyte differentiation	biological process	GO:0048709	85	4	18204	50	CNTN1,NTRK2,PTPRZ1,CLU
8.752e-05	-9.34	DGUOK (deoxyguanosine kinase)	protein interactions	1716	91	4	19454	50	NTM,ANK2,CNTN1,GPM6A
8.816e-05	-9.34	regulation of cell projection organization	biological process	GO:0031344	683	9	18204	50	MAGI2,TNIK,NTRK2,APOE,GFAP,FUT9,CTNNA2,GPM6A,CNTN1
9.242e-05	-9.29	glutamatergic synapse	cellular component	GO:0098978	412	7	19108	50	GPM6A,TNIK,NRG3,ERBB4,SLC1A2,PLCB1,APOE
9.955e-05	-9.21	oesophagus-middle_third-carcinoma-squamous_cell_carcinoma	COSMIC cancer mutations	oesophagus-middle_third-carcinoma-squamous_cell_carcinoma	3531	22	16828	48	NRG3,CTNND2,SOX5,PTPRZ1,PCDH9,PARD3,ADCY2,RGS6,RYR3,GFAP,HPSE2,GPC5,NEBL,LRP1B,GPM6A,MAGI2,TNC,FMN2,TRPM3,TNIK,ABLIM1,ANK2
1.004e-04	-9.21	middle_third	COSMIC cancer mutations	middle_third	3533	22	16828	48	CTNND2,ANK2,TNIK,MAGI2,GPM6A,LRP1B,TNC,GFAP,RGS6,RYR3,ADCY2,PARD3,PCDH9,PTPRZ1,SOX5,NRG3,TRPM3,FMN2,ABLIM1,NEBL,HPSE2,GPC5
1.030e-04	-9.18	animal organ development	biological process	GO:0048513	2846	19	18204	50	MAGI2,RORA,PLCB1,ERBB4,CTNNA2,SOX5,CNTN1,CPE,NRG3,ANK2,PCDH9,TNC,NEBL,NTRK2,PRKG1,ABLIM1,NFIA,GPM6A,SLC1A2
1.099e-04	-9.12	negative regulation of amide metabolic process	biological process	GO:0034249	34	3	18204	50	APOE,NTRK2,CLU
1.101e-04	-9.11	D-amino acid transport	biological process	GO:0042940	6	2	18204	50	SLC1A2,GFAP
1.101e-04	-9.11	ERBB4-ERBB4 signaling pathway	biological process	GO:0038138	6	2	18204	50	NRG3,ERBB4
1.138e-04	-9.08	upper_aerodigestive_tract	COSMIC cancer mutations	upper_aerodigestive_tract	13181	47	16828	48	NRXN1,SLC1A2,NFIA,RBMS3,APOE,MAGI2,PPP2R2B,CDH20,RYR3,PCDH9,NRG3,MGAT4C,SORBS1,NEBL,CNTN1,ABLIM1,FUT9,HPSE2,NKAIN3,DTNA,CTNND2,CLU,TNC,GPM6A,LRP1B,ANK2,TNIK,LSAMP,GFAP,RGS6,RORA,PARD3,ADCY2,NPAS3,NTRK2,PRKG1,GLIS3,PTPRZ1,SOX5,NTM,PLCB1,CADM2,PITPNC1,ERBB4,TRPM3,FMN2,GPC5
1.143e-04	-9.08	localization within membrane	biological process	GO:0051668	549	8	18204	50	APOE,ANK2,PARD3,MAGI2,TNIK,NRXN1,CPE,ERBB4
1.167e-04	-9.06	PRRG4 (proline rich and Gla domain 4)	protein interactions	79056	37	3	19454	50	ERBB4,MAGI2,NEBL
1.167e-04	-9.06	MAGI2 (membrane associated guanylate kinase, WW and PDZ domain containing 2)	protein interactions	9863	37	3	19454	50	CTNND2,ERBB4,MAGI2
1.167e-04	-9.06	DNAAF2 (dynein axonemal assembly factor 2)	protein interactions	55172	98	4	19454	50	LSAMP,CNTN1,ANK2,GPM6A
1.174e-04	-9.05	forebrain development	biological process	GO:0030900	408	7	18204	50	NTRK2,SLC1A2,PLCB1,NRG3,PCDH9,ERBB4,PRKG1
1.176e-04	-9.05	thyroid-carcinoma	COSMIC cancer mutations	thyroid-carcinoma	4126	24	16828	48	CTNND2,NFIA,DTNA,NRXN1,RYR3,RGS6,LSAMP,TNIK,ANK2,LRP1B,MAGI2,CPE,PLCB1,SOX5,PTPRZ1,GLIS3,PRKG1,ADCY2,PCDH9,PARD3,FUT9,GPC5,TRPM3,ERBB4
1.176e-04	-9.05	proteoglycan binding	molecular function	GO:0043394	36	3	18094	48	HPSE2,APOE,TNC
1.293e-04	-8.95	adherens junction	cellular component	GO:0005912	188	5	19108	50	PARD3,SORBS1,CTNNA2,CTNND2,CDH20
1.374e-04	-8.89	C11orf52 (chromosome 11 open reading frame 52)	protein interactions	91894	310	6	19454	50	TNIK,DTNA,PLCB1,FMN2,ABLIM1,PARD3
1.404e-04	-8.87	axon development	biological process	GO:0061564	420	7	18204	50	PTPRZ1,TNC,PARD3,PRKG1,CTNNA2,NRXN1,CNTN1
1.460e-04	-8.83	spleen	COSMIC cancer mutations	spleen	408	7	16828	48	SORBS1,LRP1B,ADCY2,ANK2,TNIK,PTPRZ1,NTM
1.490e-04	-8.81	FLOT1 (flotillin 1)	protein interactions	10211	453	7	19454	50	SOX5,SORBS1,DTNA,PARD3,ANK2,FMN2,ABLIM1
1.612e-04	-8.73	bone	COSMIC cancer mutations	bone	8157	36	16828	48	CTNND2,DTNA,NKAIN3,NRXN1,RORA,RGS6,RYR3,LSAMP,PPP2R2B,ANK2,TNIK,GPM6A,LRP1B,CPE,TNC,PLCB1,PTPRZ1,SOX5,NRG3,GLIS3,NTRK2,PRKG1,ADCY2,NPAS3,PARD3,PCDH9,HPSE2,GPC5,TRPM3,FMN2,CNTN1,ERBB4,ABLIM1,SORBS1,NEBL,CADM2
1.688e-04	-8.69	bone-femur-other-chondroblastoma	COSMIC cancer mutations	bone-femur-other-chondroblastoma	183	5	16828	48	LRP1B,RYR3,NRG3,PCDH9,GPC5
1.795e-04	-8.63	LHB (luteinizing hormone subunit beta)	protein interactions	3972	8	2	19454	50	NTM,GFAP
1.841e-04	-8.60	beta-catenin binding	molecular function	GO:0008013	107	4	18094	48	RORA,CTNND2,CTNNA2,CDH20
1.886e-04	-8.58	cellular component biogenesis	biological process	GO:0044085	2716	18	18204	50	ABLIM1,SLC1A2,SORBS1,GPM6A,NRXN1,NRG3,PARD3,ANK2,CLU,RYR3,NEBL,TRPM3,APOE,ERBB4,CDH20,CNTN1,TNIK,FMN2
1.949e-04	-8.54	cell morphogenesis involved in neuron differentiation	biological process	GO:0048667	443	7	18204	50	CTNNA2,PRKG1,CNTN1,NRXN1,CTNND2,PARD3,PTPRZ1
2.048e-04	-8.49	protein import	biological process	GO:0017038	8	2	18204	50	CLU,APOE
2.048e-04	-8.49	ERBB4 signaling pathway	biological process	GO:0038130	8	2	18204	50	ERBB4,NRG3
2.284e-04	-8.38	skin-head_neck-malignant_melanoma-superficial_spreading	COSMIC cancer mutations	skin-head_neck-malignant_melanoma-superficial_spreading	923	10	16828	48	MGAT4C,PLCB1,FUT9,CTNND2,SORBS1,LRP1B,TNC,PPP2R2B,ADCY2,ERBB4
2.304e-04	-8.38	LSAMP (limbic system associated membrane protein)	protein interactions	4045	9	2	19454	50	NTM,LSAMP
2.304e-04	-8.38	NEGR1 (neuronal growth regulator 1)	protein interactions	257194	9	2	19454	50	LSAMP,NTM
2.544e-04	-8.28	adenoid_cystic_carcinoma	COSMIC cancer mutations	adenoid_cystic_carcinoma	1123	11	16828	48	LRP1B,MAGI2,CADM2,TNIK,ERBB4,RYR3,PRKG1,NTRK2,MGAT4C,RORA,CTNND2
2.564e-04	-8.27	OCLN (occludin)	protein interactions	100506658	495	7	19454	50	FMN2,ABLIM1,NTRK2,TNIK,DTNA,PARD3,ANK2
2.596e-04	-8.26	lung-carcinoma-small_cell_carcinoma	COSMIC cancer mutations	lung-carcinoma-small_cell_carcinoma	9908	40	16828	48	NKAIN3,NRXN1,CLU,CTNND2,NFIA,DTNA,PPP2R2B,ANK2,TNIK,MAGI2,GPM6A,LRP1B,TNC,CPE,RORA,RGS6,CDH20,RYR3,NPAS3,PARD3,PCDH9,MGAT4C,PLCB1,PTPRZ1,SOX5,NTM,NRG3,NTRK2,PRKG1,TRPM3,FMN2,CNTN1,ERBB4,ABLIM1,SORBS1,PITPNC1,NEBL,CADM2,HPSE2,GPC5
2.635e-04	-8.24	small_cell_carcinoma	COSMIC cancer mutations	small_cell_carcinoma	9913	40	16828	48	CPE,TNC,MAGI2,GPM6A,LRP1B,ANK2,TNIK,PPP2R2B,RYR3,CDH20,RGS6,RORA,NKAIN3,NRXN1,DTNA,NFIA,CLU,CTNND2,CADM2,PITPNC1,SORBS1,NEBL,CNTN1,ERBB4,ABLIM1,TRPM3,FMN2,GPC5,HPSE2,PARD3,PCDH9,NPAS3,NTRK2,PRKG1,NRG3,PTPRZ1,SOX5,NTM,MGAT4C,PLCB1
2.663e-04	-8.23	intestinal_adenocarcinoma	COSMIC cancer mutations	intestinal_adenocarcinoma	7225	33	16828	48	HPSE2,FMN2,TRPM3,CNTN1,ERBB4,NEBL,PITPNC1,CADM2,PLCB1,SOX5,NTM,PTPRZ1,NRG3,PRKG1,NTRK2,NPAS3,ADCY2,PCDH9,PARD3,RORA,RYR3,CDH20,GFAP,LSAMP,ANK2,LRP1B,MAGI2,TNC,CTNND2,CLU,NFIA,SLC1A2,NRXN1
2.663e-04	-8.23	stomach-carcinoma-intestinal_adenocarcinoma	COSMIC cancer mutations	stomach-carcinoma-intestinal_adenocarcinoma	7225	33	16828	48	NPAS3,ADCY2,PCDH9,PARD3,SOX5,NTM,PTPRZ1,PLCB1,PRKG1,NTRK2,NRG3,CNTN1,ERBB4,FMN2,TRPM3,CADM2,NEBL,PITPNC1,HPSE2,SLC1A2,NRXN1,CTNND2,CLU,NFIA,ANK2,LSAMP,TNC,LRP1B,MAGI2,RORA,CDH20,RYR3,GFAP
2.723e-04	-8.21	receptor clustering	biological process	GO:0043113	46	3	18204	50	MAGI2,NRXN1,APOE
2.876e-04	-8.15	salivary_gland	COSMIC cancer mutations	salivary_gland	1139	11	16828	48	ERBB4,TNIK,MAGI2,LRP1B,CADM2,RORA,MGAT4C,CTNND2,RYR3,NTRK2,PRKG1
2.879e-04	-8.15	pancreas-carcinoid-endocrine_tumour	COSMIC cancer mutations	pancreas-carcinoid-endocrine_tumour	7250	33	16828	48	PCDH9,PARD3,ADCY2,PRKG1,NTRK2,GLIS3,NRG3,SOX5,PLCB1,CADM2,NEBL,ABLIM1,CNTN1,ERBB4,FMN2,GPC5,HPSE2,NKAIN3,SLC1A2,CTNND2,CLU,CPE,TNC,LRP1B,APOE,MAGI2,GPM6A,ANK2,LSAMP,PPP2R2B,CDH20,RYR3,RORA
2.906e-04	-8.14	mixed_intestinal_and_diffuse_adenocarcinoma-unclassifiable	COSMIC cancer mutations	mixed_intestinal_and_diffuse_adenocarcinoma-unclassifiable	951	10	16828	48	CNTN1,ANK2,TRPM3,FMN2,SLC1A2,TNC,PARD3,MAGI2,LRP1B,GPC5
2.906e-04	-8.14	stomach-carcinoma-mixed_intestinal_and_diffuse_adenocarcinoma-unclassifiable	COSMIC cancer mutations	stomach-carcinoma-mixed_intestinal_and_diffuse_adenocarcinoma-unclassifiable	951	10	16828	48	GPC5,MAGI2,LRP1B,PARD3,TNC,TRPM3,FMN2,SLC1A2,ANK2,CNTN1
2.956e-04	-8.13	somatodendritic compartment	cellular component	GO:0036477	842	9	19108	50	MAGI2,CTNND2,NRXN1,CADM2,CLU,GPM6A,ADCY2,APOE,NTRK2
3.069e-04	-8.09	synapse assembly	biological process	GO:0007416	118	4	18204	50	NRG3,ERBB4,GPM6A,NRXN1
3.091e-04	-8.08	regulation of amyloid-beta formation	biological process	GO:1902003	48	3	18204	50	CLU,APOE,NTRK2
3.193e-04	-8.05	diffuse_adenocarcinoma	COSMIC cancer mutations	diffuse_adenocarcinoma	4383	24	16828	48	ANK2,LRP1B,GPM6A,MAGI2,TNC,RYR3,CLU,CTNND2,DTNA,FMN2,TRPM3,ABLIM1,CNTN1,ERBB4,CADM2,ADCY2,PCDH9,PARD3,MGAT4C,SOX5,PTPRZ1,GLIS3,NRG3,PRKG1
3.193e-04	-8.05	stomach-carcinoma-diffuse_adenocarcinoma	COSMIC cancer mutations	stomach-carcinoma-diffuse_adenocarcinoma	4383	24	16828	48	RYR3,ANK2,LRP1B,MAGI2,GPM6A,TNC,CLU,CTNND2,DTNA,FMN2,TRPM3,ABLIM1,CNTN1,ERBB4,CADM2,MGAT4C,SOX5,PTPRZ1,GLIS3,NRG3,PRKG1,ADCY2,PCDH9,PARD3
3.231e-04	-8.04	SH2B2 (SH2B adaptor protein 2)	protein interactions	10603	52	3	19454	50	ERBB4,SORBS1,NTRK2
3.377e-04	-7.99	leg	COSMIC cancer mutations	leg	969	10	16828	48	PTPRZ1,NTM,PLCB1,PRKG1,NRG3,CNTN1,FMN2,MAGI2,NEBL,LRP1B
3.403e-04	-7.99	Signaling by ERBB4	REACTOME pathways	R-HSA-1236394	43	3	10285	33	NRG3,ERBB4,GFAP
3.534e-04	-7.95	cell-cell signaling	biological process	GO:0007267	822	9	18204	50	NRXN1,CPE,SLC1A2,APOE,PLCB1,NTRK2,TNC,DTNA,ANK2
3.636e-04	-7.92	perisynaptic extracellular matrix	cellular component	GO:0098966	11	2	19108	50	TNC,PTPRZ1
3.702e-04	-7.90	EZR (ezrin)	protein interactions	7430	526	7	19454	50	MAPK10,ABLIM1,DTNA,SORBS1,TNIK,ANK2,NEBL
3.789e-04	-7.88	prostate-carcinoma-adenocarcinoma	COSMIC cancer mutations	prostate-carcinoma-adenocarcinoma	12379	45	16828	48	RORA,GFAP,RGS6,RYR3,CDH20,PPP2R2B,LSAMP,ANK2,TNIK,MAGI2,GPM6A,LRP1B,TNC,CPE,CLU,CTNND2,NFIA,SLC1A2,NKAIN3,NRXN1,FUT9,HPSE2,GPC5,TRPM3,FMN2,ERBB4,CNTN1,ABLIM1,SORBS1,PITPNC1,NEBL,CADM2,MGAT4C,PLCB1,PTPRZ1,NTM,SOX5,NRG3,GLIS3,NTRK2,PRKG1,ADCY2,NPAS3,PARD3,PCDH9
4.023e-04	-7.82	L1CAM (L1 cell adhesion molecule)	protein interactions	3897	56	3	19454	50	GPM6A,CNTN1,ANK2
4.023e-04	-7.82	CSTL1 (cystatin like 1)	protein interactions	128817	56	3	19454	50	APOE,CPE,CLU
4.203e-04	-7.77	PROK2 (prokineticin 2)	protein interactions	60675	12	2	19454	50	CPE,LRP1B
4.203e-04	-7.77	TREM2 (triggering receptor expressed on myeloid cells 2)	protein interactions	54209	12	2	19454	50	CLU,APOE
4.301e-04	-7.75	LYN (LYN proto-oncogene, Src family tyrosine kinase)	protein interactions	4067	713	8	19454	50	TNIK,ABLIM1,FMN2,ERBB4,ANK2,DTNA,PLCB1,PARD3
4.343e-04	-7.74	salivary_gland-carcinoma-adenoid_cystic_carcinoma	COSMIC cancer mutations	salivary_gland-carcinoma-adenoid_cystic_carcinoma	488	7	16828	48	MGAT4C,RORA,CTNND2,MAGI2,RYR3,CADM2,PRKG1
4.355e-04	-7.74	synapse-associated extracellular matrix	cellular component	GO:0099535	12	2	19108	50	TNC,PTPRZ1
4.358e-04	-7.74	Salivary secretion	KEGG pathways	hsa04970	90	4	7161	29	PRKG1,PLCB1,RYR3,ADCY2
4.358e-04	-7.74	Salivary secretion	KEGG pathways	ko04970	90	4	7161	29	PRKG1,PLCB1,RYR3,ADCY2
4.371e-04	-7.74	I-set	pfam domains	PF07679	132	4	17795	48	NTM,LSAMP,NTRK2,CNTN1
4.404e-04	-7.73	Ig_I-set	interpro domains	IPR013098	132	4	18521	50	CNTN1,LSAMP,NTM,NTRK2
4.421e-04	-7.72	PI3K events in ERBB4 signaling	REACTOME pathways	R-HSA-1250342	10	2	10285	33	ERBB4,NRG3
4.441e-04	-7.72	positive regulation of cell projection organization	biological process	GO:0031346	361	6	18204	50	FUT9,MAGI2,GPM6A,NTRK2,CNTN1,APOE
4.529e-04	-7.70	Ig_sub2	interpro domains	IPR003598	239	5	18521	50	CADM2,NTRK2,NTM,CNTN1,LSAMP
4.590e-04	-7.69	urinary_tract-bladder-carcinoma-transitional_cell_carcinoma	COSMIC cancer mutations	urinary_tract-bladder-carcinoma-transitional_cell_carcinoma	6040	29	16828	48	GPC5,HPSE2,SORBS1,NEBL,ERBB4,ABLIM1,TRPM3,FMN2,NTRK2,PRKG1,NRG3,GLIS3,PTPRZ1,MGAT4C,PLCB1,PARD3,PCDH9,ADCY2,CDH20,RGS6,TNC,GPM6A,MAGI2,LRP1B,ANK2,DTNA,NFIA,CLU,NRXN1
4.599e-04	-7.68	biliary_tract-gallbladder-carcinoma-adenocarcinoma	COSMIC cancer mutations	biliary_tract-gallbladder-carcinoma-adenocarcinoma	2821	18	16828	48	CLU,CTNND2,PTPRZ1,NRG3,PRKG1,NKAIN3,PCDH9,PARD3,RYR3,FMN2,TRPM3,TNIK,ANK2,ERBB4,LRP1B,MAGI2,PITPNC1,TNC
4.599e-04	-7.68	gallbladder	COSMIC cancer mutations	gallbladder	2821	18	16828	48	TNIK,ERBB4,ANK2,FMN2,TRPM3,TNC,LRP1B,MAGI2,PITPNC1,RYR3,PCDH9,PARD3,NKAIN3,CTNND2,CLU,PTPRZ1,PRKG1,NRG3
4.619e-04	-7.68	transitional_cell_carcinoma	COSMIC cancer mutations	transitional_cell_carcinoma	6042	29	16828	48	CLU,NFIA,DTNA,NRXN1,RGS6,CDH20,ANK2,MAGI2,GPM6A,LRP1B,TNC,MGAT4C,PLCB1,PTPRZ1,NRG3,GLIS3,NTRK2,PRKG1,ADCY2,PARD3,PCDH9,HPSE2,GPC5,TRPM3,FMN2,ERBB4,ABLIM1,SORBS1,NEBL
4.626e-04	-7.68	regulation of amyloid precursor protein catabolic process	biological process	GO:1902991	55	3	18204	50	CLU,NTRK2,APOE
4.776e-04	-7.65	axonogenesis	biological process	GO:0007409	366	6	18204	50	PARD3,PTPRZ1,CTNNA2,PRKG1,CNTN1,NRXN1
4.785e-04	-7.64	cytoskeleton organization	biological process	GO:0007010	1251	11	18204	50	NEBL,APOE,ANK2,PARD3,FMN2,TNIK,SORBS1,CTNNA2,GFAP,PRKG1,ABLIM1
4.842e-04	-7.63	signal transduction	biological process	GO:0007165	4637	24	18204	50	RYR3,NRG3,ANK2,PARD3,NTRK2,ADCY2,PRKG1,SORBS1,FMN2,MAGI2,DTNA,RORA,MAPK10,ERBB4,CLU,APOE,PITPNC1,NFIA,CTNND2,TNIK,PLCB1,CPE,CNTN1,RGS6
4.878e-04	-7.63	prostate-adenoma	COSMIC cancer mutations	prostate-adenoma	1634	13	16828	48	PRKG1,SOX5,PTPRZ1,PARD3,NPAS3,RGS6,GPC5,NEBL,LRP1B,MAGI2,CADM2,TRPM3,ERBB4
4.893e-04	-7.62	anchoring junction	cellular component	GO:0070161	902	9	19108	50	CTNNA2,PARD3,TNC,SORBS1,ANK2,CDH20,PCDH9,MAGI2,CTNND2
4.958e-04	-7.61	GPM6A (glycoprotein M6A)	protein interactions	2823	143	4	19454	50	CPE,ANK2,CNTN1,NTM
5.164e-04	-7.57	sarcolemma	cellular component	GO:0042383	142	4	19108	50	PRKG1,DTNA,ANK2,RYR3
5.175e-04	-7.57	HAX1 (HCLS1 associated protein X-1)	protein interactions	10456	397	6	19454	50	ANK2,CNTN1,GPM6A,NTM,CLU,MAPK10
5.199e-04	-7.56	CTNNB1 (catenin beta 1)	protein interactions	1499	926	9	19454	50	ANK2,PARD3,MAGI2,PTPRZ1,DTNA,SORBS1,CTNNA2,APOE,CTNND2
5.571e-04	-7.49	Circadian entrainment	KEGG pathways	hsa04713	96	4	7161	29	ADCY2,RYR3,PLCB1,PRKG1
5.571e-04	-7.49	Circadian entrainment	KEGG pathways	ko04713	96	4	7161	29	PLCB1,RYR3,ADCY2,PRKG1
5.583e-04	-7.49	regulation of synapse organization	biological process	GO:0050807	246	5	18204	50	CTNNA2,NTRK2,GPM6A,APOE,NRXN1
5.607e-04	-7.49	Ig_3	pfam domains	PF13927	141	4	17795	48	CADM2,NTM,LSAMP,CNTN1
5.657e-04	-7.48	negative regulation of amyloid fibril formation	biological process	GO:1905907	13	2	18204	50	APOE,CLU
5.676e-04	-7.47	endometrium-carcinoma-serous_carcinoma	COSMIC cancer mutations	endometrium-carcinoma-serous_carcinoma	1442	12	16828	48	PARD3,NRXN1,CTNND2,TNIK,CNTN1,FMN2,TRPM3,LSAMP,LRP1B,SORBS1,GPC5,RYR3
5.739e-04	-7.46	cell body	cellular component	GO:0044297	556	7	19108	50	GFAP,APOE,SLC1A2,NRXN1,CTNND2,CADM2,GPM6A
5.776e-04	-7.46	PLXNA4 (plexin A4)	protein interactions	91584	14	2	19454	50	GPM6A,CLU
5.776e-04	-7.46	C9 (complement C9)	protein interactions	735	14	2	19454	50	APOE,CLU
5.850e-04	-7.44	cellular component organization	biological process	GO:0016043	5636	27	18204	50	TNIK,CDH20,CTNNA2,CNTN1,CLU,PTPRZ1,HPSE2,TRPM3,APOE,NEBL,PITPNC1,ABLIM1,NFIA,GFAP,CTNND2,FMN2,ERBB4,TNC,RYR3,PARD3,ANK2,NRG3,PRKG1,NRXN1,SLC1A2,SORBS1,GPM6A
5.887e-04	-7.44	autonomic_ganglia-neuroblastoma	COSMIC cancer mutations	autonomic_ganglia-neuroblastoma	3970	22	16828	48	TNIK,TNC,GPM6A,LRP1B,RYR3,SLC1A2,CTNND2,NFIA,ERBB4,FMN2,PITPNC1,NEBL,FUT9,ADCY2,NPAS3,PARD3,PCDH9,PTPRZ1,PLCB1,NTRK2,PRKG1,GLIS3
5.909e-04	-7.43	neuroblastoma	COSMIC cancer mutations	neuroblastoma	3971	22	16828	48	RYR3,TNC,LRP1B,GPM6A,TNIK,NFIA,CTNND2,SLC1A2,FUT9,NEBL,PITPNC1,ERBB4,FMN2,PRKG1,NTRK2,GLIS3,PTPRZ1,PLCB1,PCDH9,PARD3,NPAS3,ADCY2
5.914e-04	-7.43	synaptic membrane	cellular component	GO:0097060	400	6	19108	50	GPM6A,CNTN1,SLC1A2,NRXN1,ERBB4,ANK2
6.086e-04	-7.40	TNIK (TRAF2 and NCK interacting kinase)	protein interactions	23043	151	4	19454	50	TNIK,ANK2,CLU,PRKG1
6.116e-04	-7.40	calcium ion transport	biological process	GO:0006816	251	5	18204	50	ANK2,RYR3,GPM6A,PLCB1,TRPM3
6.132e-04	-7.40	intracellular signal transduction	biological process	GO:0035556	1505	12	18204	50	MAGI2,TNIK,FMN2,MAPK10,PLCB1,RGS6,NRG3,ANK2,RYR3,ADCY2,APOE,PRKG1
6.227e-04	-7.38	regulation of synapse structure or activity	biological process	GO:0050803	252	5	18204	50	CTNNA2,GPM6A,NTRK2,NRXN1,APOE
6.366e-04	-7.36	Neurexin-like	interpro domains	IPR003585	14	2	18521	50	NRXN1,CADM2
6.580e-04	-7.33	presynapse	cellular component	GO:0098793	569	7	19108	50	TNIK,GPM6A,NRXN1,ERBB4,NTRK2,CNTN1,SLC1A2
6.654e-04	-7.32	TIAM2 (TIAM Rac1 associated GEF 2)	protein interactions	26230	15	2	19454	50	PARD3,TNIK
6.654e-04	-7.32	RNASE13 (ribonuclease A family member 13 (inactive))	protein interactions	440163	15	2	19454	50	CLU,CPE
6.693e-04	-7.31	autonomic_ganglia	COSMIC cancer mutations	autonomic_ganglia	4005	22	16828	48	LRP1B,NEBL,PITPNC1,GPM6A,TNC,FMN2,TNIK,ERBB4,RYR3,FUT9,PCDH9,PARD3,SLC1A2,NPAS3,ADCY2,NFIA,GLIS3,PRKG1,NTRK2,PLCB1,CTNND2,PTPRZ1
6.858e-04	-7.28	cell-cell adhesion	biological process	GO:0098609	546	7	18204	50	CTNND2,CADM2,NRXN1,CNTN1,CTNNA2,CDH20,PCDH9
6.985e-04	-7.27	soft_tissue-striated_muscle-rhabdomyosarcoma-embryonal	COSMIC cancer mutations	soft_tissue-striated_muscle-rhabdomyosarcoma-embryonal	2659	17	16828	48	NPAS3,ADCY2,NFIA,GLIS3,CTNND2,PTPRZ1,LRP1B,SORBS1,APOE,MAGI2,TNC,FMN2,TRPM3,ANK2,RGS6,RYR3,RORA
6.985e-04	-7.27	embryonal	COSMIC cancer mutations	embryonal	2659	17	16828	48	TRPM3,FMN2,ANK2,MAGI2,APOE,SORBS1,LRP1B,TNC,RORA,RGS6,RYR3,ADCY2,NPAS3,PTPRZ1,CTNND2,NFIA,GLIS3
7.388e-04	-7.21	upper_aerodigestive_tract-pharynx-carcinoma-squamous_cell_carcinoma	COSMIC cancer mutations	upper_aerodigestive_tract-pharynx-carcinoma-squamous_cell_carcinoma	1485	12	16828	48	GPC5,PTPRZ1,FUT9,DTNA,RYR3,NRG3,NPAS3,ANK2,FMN2,PCDH9,LRP1B,SORBS1
7.544e-04	-7.19	positive regulation of cellular process	biological process	GO:0048522	5719	27	18204	50	CLU,PTPRZ1,HPSE2,APOE,NFIA,FUT9,GFAP,TNIK,PLCB1,GPC5,CNTN1,SOX5,TNC,PARD3,ANK2,NTRK2,NRXN1,RBMS3,SLC1A2,GPM6A,NPAS3,SORBS1,MAGI2,FMN2,RORA,ERBB4,GLIS3
7.565e-04	-7.19	ovary-carcinoma-serous_carcinoma	COSMIC cancer mutations	ovary-carcinoma-serous_carcinoma	10710	41	16828	48	PCDH9,PARD3,NPAS3,ADCY2,PRKG1,NTRK2,GLIS3,NRG3,NTM,SOX5,PTPRZ1,PLCB1,MGAT4C,CADM2,NEBL,SORBS1,CNTN1,ERBB4,FMN2,TRPM3,GPC5,HPSE2,FUT9,NRXN1,SLC1A2,DTNA,CLU,CTNND2,TNC,CPE,LRP1B,MAGI2,TNIK,ANK2,LSAMP,PPP2R2B,RYR3,RGS6,CDH20,GFAP,RORA
7.588e-04	-7.18	sarcoplasmic reticulum calcium ion transport	biological process	GO:0070296	15	2	18204	50	RYR3,ANK2
7.617e-04	-7.18	ERBB2 Activates PTK6 Signaling	REACTOME pathways	R-HSA-8847993	13	2	10285	33	NRG3,ERBB4
8.047e-04	-7.13	cell migration	biological process	GO:0016477	921	9	18204	50	GPM6A,CDH20,PRKG1,CTNNA2,ERBB4,GPC5,NTRK2,FMN2,NRG3
8.309e-04	-7.09	PARD3 (par-3 family cell polarity regulator)	protein interactions	56288	287	5	19454	50	NTRK2,SORBS1,PLCB1,DTNA,PARD3
8.381e-04	-7.08	regulation of localization	biological process	GO:0032879	2028	14	18204	50	NKAIN3,MAGI2,GPC5,PLCB1,ERBB4,CNTN1,ANK2,CLU,RYR3,APOE,GFAP,PRKG1,SLC1A2,SORBS1
8.382e-04	-7.08	hindbrain development	biological process	GO:0030902	154	4	18204	50	CTNNA2,PRKG1,CNTN1,RORA
8.440e-04	-7.08	VASP (vasodilator stimulated phosphoprotein)	protein interactions	7408	288	5	19454	50	NEBL,PRKG1,SORBS1,FMN2,PARD3
8.657e-04	-7.05	asymmetric cell division	biological process	GO:0008356	16	2	18204	50	SOX5,PARD3
8.869e-04	-7.03	SHC1 events in ERBB4 signaling	REACTOME pathways	R-HSA-1250347	14	2	10285	33	ERBB4,NRG3
8.890e-04	-7.03	cellular response to endogenous stimulus	biological process	GO:0071495	1135	10	18204	50	SLC1A2,SORBS1,SOX5,ERBB4,NFIA,NTRK2,PLCB1,MAGI2,TNC,RYR3
9.341e-04	-6.98	large_intestine-adenoma	COSMIC cancer mutations	large_intestine-adenoma	266	5	16828	48	SOX5,LRP1B,CDH20,RYR3,APOE
9.374e-04	-6.97	telencephalon development	biological process	GO:0021537	276	5	18204	50	ERBB4,NRG3,NTRK2,SLC1A2,PLCB1
9.374e-04	-6.97	learning or memory	biological process	GO:0007611	276	5	18204	50	NRXN1,APOE,PLCB1,NTRK2,PTPRZ1
9.794e-04	-6.93	regulation of amyloid fibril formation	biological process	GO:1905906	17	2	18204	50	APOE,CLU
9.794e-04	-6.93	reverse cholesterol transport	biological process	GO:0043691	17	2	18204	50	CLU,APOE
1.021e-03	-6.89	ERBB2 Regulates Cell Motility	REACTOME pathways	R-HSA-6785631	15	2	10285	33	NRG3,ERBB4
1.022e-03	-6.89	oesophagus-lower_third-carcinoma-adenocarcinoma	COSMIC cancer mutations	oesophagus-lower_third-carcinoma-adenocarcinoma	6302	29	16828	48	NRXN1,CTNND2,TNC,CPE,LRP1B,MAGI2,ANK2,RGS6,RYR3,CDH20,RORA,PCDH9,PARD3,NPAS3,ADCY2,NTRK2,NRG3,SOX5,PTPRZ1,PLCB1,MGAT4C,CADM2,NEBL,SORBS1,CNTN1,ERBB4,FMN2,TRPM3,GPC5
1.026e-03	-6.88	heparan sulfate proteoglycan binding	molecular function	GO:0043395	18	2	18094	48	HPSE2,APOE
1.077e-03	-6.83	TNR (tenascin R)	protein interactions	7143	19	2	19454	50	PTPRZ1,CNTN1
1.080e-03	-6.83	prostate	COSMIC cancer mutations	prostate	13883	47	16828	48	NRG3,MGAT4C,PCDH9,HPSE2,FUT9,SORBS1,NEBL,CNTN1,ABLIM1,NFIA,NRXN1,SLC1A2,CDH20,RYR3,APOE,MAGI2,CPE,PPP2R2B,GLIS3,NTRK2,PRKG1,PLCB1,PTPRZ1,SOX5,NTM,PARD3,ADCY2,NPAS3,GPC5,PITPNC1,CADM2,TRPM3,FMN2,ERBB4,DTNA,CTNND2,CLU,NKAIN3,GFAP,RGS6,RORA,GPM6A,LRP1B,TNC,LSAMP,ANK2,TNIK
1.088e-03	-6.82	dendrite	cellular component	GO:0030425	620	7	19108	50	CLU,CTNND2,MAGI2,ADCY2,GPM6A,NTRK2,APOE
1.090e-03	-6.82	adrenal_cortical_carcinoma	COSMIC cancer mutations	adrenal_cortical_carcinoma	2256	15	16828	48	SOX5,CTNND2,PTPRZ1,NRG3,NTRK2,SLC1A2,PCDH9,HPSE2,FMN2,TRPM3,ANK2,CNTN1,LRP1B,MAGI2,TNC
1.100e-03	-6.81	negative regulation of platelet activation	biological process	GO:0010544	18	2	18204	50	APOE,PRKG1
1.100e-03	-6.81	positive regulation of circadian rhythm	biological process	GO:0042753	18	2	18204	50	PRKG1,RORA
1.108e-03	-6.80	dendritic tree	cellular component	GO:0097447	622	7	19108	50	NTRK2,APOE,ADCY2,GPM6A,CTNND2,MAGI2,CLU
1.112e-03	-6.80	cellular component organization or biogenesis	biological process	GO:0071840	5850	27	18204	50	TNC,RYR3,PARD3,NRG3,ANK2,NRXN1,SLC1A2,SORBS1,GPM6A,PRKG1,FMN2,ERBB4,TRPM3,APOE,NEBL,PITPNC1,CLU,PTPRZ1,HPSE2,CTNND2,NFIA,ABLIM1,GFAP,TNIK,CNTN1,CDH20,CTNNA2
1.114e-03	-6.80	acral_lentiginous	COSMIC cancer mutations	acral_lentiginous	745	8	16828	48	PLCB1,NRG3,CDH20,ERBB4,LRP1B,PARD3,TNC,CADM2
1.115e-03	-6.80	astrocyte projection	cellular component	GO:0097449	19	2	19108	50	SLC1A2,GFAP
1.124e-03	-6.79	ERBB4 (erb-b2 receptor tyrosine kinase 4)	protein interactions	2066	178	4	19454	50	ERBB4,MAGI2,NRG3,NTRK2
1.165e-03	-6.76	PI3K events in ERBB2 signaling	REACTOME pathways	R-HSA-1963642	16	2	10285	33	ERBB4,NRG3
1.165e-03	-6.76	GRB2 events in ERBB2 signaling	REACTOME pathways	R-HSA-1963640	16	2	10285	33	NRG3,ERBB4
1.194e-03	-6.73	PDZD2 (PDZ domain containing 2)	protein interactions	23037	20	2	19454	50	NRXN1,CTNND2
1.220e-03	-6.71	PRPH (peripherin)	protein interactions	5630	182	4	19454	50	GFAP,PPP2R2B,SORBS1,ABLIM1
1.225e-03	-6.70	kidney-carcinoma-papillary_renal_cell_carcinoma	COSMIC cancer mutations	kidney-carcinoma-papillary_renal_cell_carcinoma	6364	29	16828	48	CLU,CTNND2,NFIA,NRXN1,RORA,RYR3,ANK2,TNIK,CPE,MAGI2,LRP1B,PTPRZ1,NTM,SOX5,PLCB1,NTRK2,PRKG1,NRG3,ADCY2,PARD3,GPC5,HPSE2,CNTN1,ERBB4,ABLIM1,TRPM3,FMN2,CADM2,PITPNC1
1.225e-03	-6.70	papillary_renal_cell_carcinoma	COSMIC cancer mutations	papillary_renal_cell_carcinoma	6364	29	16828	48	ADCY2,PARD3,NTM,SOX5,PTPRZ1,PLCB1,PRKG1,NTRK2,NRG3,ABLIM1,CNTN1,ERBB4,FMN2,TRPM3,CADM2,PITPNC1,GPC5,HPSE2,NRXN1,CTNND2,CLU,NFIA,TNIK,ANK2,CPE,LRP1B,MAGI2,RORA,RYR3
1.227e-03	-6.70	regulation of amyloid-beta clearance	biological process	GO:1900221	19	2	18204	50	APOE,CLU
1.227e-03	-6.70	negative regulation of alcohol biosynthetic process	biological process	GO:1902931	19	2	18204	50	PRKG1,APOE
1.283e-03	-6.66	dicarboxylic acid transport	biological process	GO:0006835	78	3	18204	50	GFAP,NTRK2,SLC1A2
1.318e-03	-6.63	SHC4 (SHC adaptor protein 4)	protein interactions	399694	21	2	19454	50	ERBB4,NTRK2
1.360e-03	-6.60	Cell-type Dependent Selectivity of CCK2R Signaling	WikiPathways	WP3679	13	2	5310	23	RYR3,PLCB1
1.361e-03	-6.60	aspartate transmembrane transport	biological process	GO:0015810	20	2	18204	50	GFAP,SLC1A2
1.386e-03	-6.58	4.1m	smart domains	SM00294	14	2	9717	39	NRXN1,CADM2
1.394e-03	-6.58	skin-scalp-carcinoma-squamous_cell_carcinoma	COSMIC cancer mutations	skin-scalp-carcinoma-squamous_cell_carcinoma	1596	12	16828	48	RBMS3,PLCB1,RORA,GPC5,SOX5,PTPRZ1,GFAP,PRKG1,LSAMP,CNTN1,ANK2,NRXN1
1.400e-03	-6.57	postsynaptic density	cellular component	GO:0014069	317	5	19108	50	MAGI2,CTNND2,ERBB4,NTRK2,TNIK
1.425e-03	-6.55	behavior	biological process	GO:0007610	619	7	18204	50	NRXN1,CNTN1,PLCB1,APOE,SLC1A2,NTRK2,PTPRZ1
1.431e-03	-6.55	regulation of amide metabolic process	biological process	GO:0034248	81	3	18204	50	APOE,NTRK2,CLU
1.481e-03	-6.52	contractile actin filament bundle	cellular component	GO:0097517	86	3	19108	50	SORBS1,NEBL,ABLIM1
1.481e-03	-6.52	stress fiber	cellular component	GO:0001725	86	3	19108	50	SORBS1,ABLIM1,NEBL
1.507e-03	-6.50	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-acute_lymphoblastic_leukaemia	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-acute_lymphoblastic_leukaemia	2081	14	16828	48	MAGI2,LRP1B,ANK2,ERBB4,TNIK,GFAP,RGS6,ADCY2,NTRK2,DTNA,PRKG1,NFIA,PTPRZ1,SOX5
1.514e-03	-6.49	signaling receptor binding	molecular function	GO:0005102	1493	11	18094	48	SORBS1,TNC,NRG3,MAGI2,GFAP,ERBB4,CPE,PTPRZ1,NRXN1,APOE,CLU
1.519e-03	-6.49	enzyme-linked receptor protein signaling pathway	biological process	GO:0007167	626	7	18204	50	ERBB4,NRG3,MAGI2,NFIA,SORBS1,NTRK2,PLCB1
1.545e-03	-6.47	synaptic signaling	biological process	GO:0099536	459	6	18204	50	DTNA,SLC1A2,NTRK2,NRXN1,PLCB1,APOE
1.548e-03	-6.47	SFN (stratifin)	protein interactions	2810	671	7	19454	50	ABLIM1,FMN2,TNIK,NFIA,PARD3,SORBS1,PPP2R2B
1.577e-03	-6.45	breast-carcinoma-ductolobular_carcinoma	COSMIC cancer mutations	breast-carcinoma-ductolobular_carcinoma	1619	12	16828	48	DTNA,CDH20,CTNND2,PTPRZ1,PLCB1,RORA,CPE,SORBS1,ABLIM1,CNTN1,ANK2,FMN2
1.577e-03	-6.45	ductolobular_carcinoma	COSMIC cancer mutations	ductolobular_carcinoma	1619	12	16828	48	FMN2,ABLIM1,CNTN1,ANK2,SORBS1,CPE,RORA,CDH20,PLCB1,CTNND2,PTPRZ1,DTNA
1.594e-03	-6.44	DEP_dom	interpro domains	IPR000591	22	2	18521	50	FMN2,RGS6
1.603e-03	-6.44	serous_carcinoma	COSMIC cancer mutations	serous_carcinoma	10987	41	16828	48	LSAMP,PPP2R2B,ANK2,TNIK,MAGI2,LRP1B,CPE,TNC,RORA,GFAP,CDH20,RYR3,RGS6,SLC1A2,NRXN1,CTNND2,CLU,DTNA,TRPM3,FMN2,ERBB4,CNTN1,SORBS1,NEBL,CADM2,FUT9,HPSE2,GPC5,ADCY2,NPAS3,PARD3,PCDH9,MGAT4C,PLCB1,PTPRZ1,NTM,SOX5,NRG3,GLIS3,NTRK2,PRKG1
1.632e-03	-6.42	cellular response to organic cyclic compound	biological process	GO:0071407	464	6	18204	50	PLCB1,RORA,SLC1A2,ADCY2,RYR3,TNC
1.667e-03	-6.40	positive regulation of biological process	biological process	GO:0048518	6326	28	18204	50	PLCB1,GPC5,TNIK,SOX5,CNTN1,APOE,HPSE2,PTPRZ1,CLU,GFAP,FUT9,NFIA,RORA,FMN2,MAGI2,GLIS3,ERBB4,NTRK2,ANK2,PARD3,TNC,SLC1A2,SORBS1,GPM6A,NPAS3,RBMS3,NRXN1,PRKG1
1.738e-03	-6.35	asymmetric synapse	cellular component	GO:0032279	333	5	19108	50	NTRK2,TNIK,MAGI2,CTNND2,ERBB4
1.779e-03	-6.33	cognition	biological process	GO:0050890	319	5	18204	50	NTRK2,APOE,PLCB1,NRXN1,PTPRZ1
1.797e-03	-6.32	actomyosin	cellular component	GO:0042641	92	3	19108	50	NEBL,ABLIM1,SORBS1
1.824e-03	-6.31	adrenal_gland	COSMIC cancer mutations	adrenal_gland	2628	16	16828	48	SLC1A2,ADCY2,PCDH9,SOX5,CTNND2,PTPRZ1,NRG3,NTRK2,FMN2,TRPM3,ANK2,CNTN1,LRP1B,MAGI2,TNC,HPSE2
1.829e-03	-6.30	ear	COSMIC cancer mutations	ear	624	7	16828	48	NPAS3,ANK2,MGAT4C,PRKG1,TNC,LRP1B,MAGI2
1.832e-03	-6.30	low-density lipoprotein particle receptor binding	molecular function	GO:0050750	24	2	18094	48	APOE,CLU
1.865e-03	-6.28	intracellular signaling cassette	biological process	GO:0141124	837	8	18204	50	APOE,MAPK10,ADCY2,MAGI2,TNIK,RYR3,ANK2,PRKG1
1.870e-03	-6.28	TNC (tenascin C)	protein interactions	3371	25	2	19454	50	CNTN1,CLU
1.913e-03	-6.26	human chr12q21.31-q21.32	chromosome location	human chr12q21.31-q21.32	1	1	26134	50	MGAT4C
1.913e-03	-6.26	human chr2q22.1-q22.2	chromosome location	human chr2q22.1-q22.2	1	1	26134	50	LRP1B
1.913e-03	-6.26	human chr15q13.3-q14	chromosome location	human chr15q13.3-q14	1	1	26134	50	RYR3
1.913e-03	-6.26	human chr3q26.2-q26.31	chromosome location	human chr3q26.2-q26.31	1	1	26134	50	TNIK
1.913e-03	-6.26	human chr4q25-q26	chromosome location	human chr4q25-q26	1	1	26134	50	ANK2
1.913e-03	-6.26	human chr9q21.12-q21.13	chromosome location	human chr9q21.12-q21.13	1	1	26134	50	TRPM3
1.913e-03	-6.26	human chr10q11.23-q21.1	chromosome location	human chr10q11.23-q21.1	1	1	26134	50	PRKG1
1.913e-03	-6.26	human chr10p11.22-p11.21	chromosome location	human chr10p11.22-p11.21	1	1	26134	50	PARD3
1.963e-03	-6.23	myelin assembly	biological process	GO:0032288	24	2	18204	50	ANK2,CNTN1
1.966e-03	-6.23	positive regulation of transport	biological process	GO:0051050	844	8	18204	50	MAGI2,CLU,ANK2,PLCB1,APOE,CNTN1,SLC1A2,SORBS1
1.987e-03	-6.22	PLCB3 (phospholipase C beta 3)	protein interactions	5331	97	3	19454	50	PLCB1,PARD3,PRKG1
1.990e-03	-6.22	RYK (receptor like tyrosine kinase)	protein interactions	6259	208	4	19454	50	CTNNA2,CNTN1,CLU,PCDH9
2.018e-03	-6.21	HS-GAG degradation	REACTOME pathways	R-HSA-2024096	21	2	10285	33	HPSE2,GPC5
2.026e-03	-6.20	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-hairy_cell_leukaemia	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-hairy_cell_leukaemia	1440	11	16828	48	RYR3,CDH20,MAGI2,LRP1B,NEBL,FMN2,ANK2,CNTN1,PTPRZ1,CTNND2,NRXN1
2.026e-03	-6.20	hairy_cell_leukaemia	COSMIC cancer mutations	hairy_cell_leukaemia	1440	11	16828	48	NRXN1,CTNND2,PTPRZ1,ANK2,CNTN1,FMN2,NEBL,LRP1B,MAGI2,CDH20,RYR3
2.029e-03	-6.20	postsynaptic specialization	cellular component	GO:0099572	345	5	19108	50	ERBB4,MAGI2,CTNND2,TNIK,NTRK2
2.030e-03	-6.20	actin filament bundle	cellular component	GO:0032432	96	3	19108	50	NEBL,ABLIM1,SORBS1
2.046e-03	-6.19	kidney-other-neoplasm	COSMIC cancer mutations	kidney-other-neoplasm	10653	40	16828	48	SLC1A2,NRXN1,NKAIN3,CLU,CTNND2,DTNA,LSAMP,PPP2R2B,TNIK,ANK2,LRP1B,MAGI2,GPM6A,CPE,TNC,RORA,CDH20,RYR3,GFAP,NPAS3,ADCY2,PCDH9,PARD3,PLCB1,MGAT4C,SOX5,PTPRZ1,NRG3,PRKG1,NTRK2,FMN2,TRPM3,ABLIM1,ERBB4,CNTN1,NEBL,SORBS1,CADM2,HPSE2,GPC5
2.047e-03	-6.19	FRS2 (fibroblast growth factor receptor substrate 2)	protein interactions	10818	98	3	19454	50	NTRK2,PARD3,SORBS1
2.055e-03	-6.19	haematopoietic_neoplasm	COSMIC cancer mutations	haematopoietic_neoplasm	11082	41	16828	48	PCDH9,PARD3,NPAS3,ADCY2,GLIS3,NRG3,PRKG1,NTRK2,PLCB1,SOX5,NTM,PTPRZ1,NEBL,CADM2,FMN2,TRPM3,ABLIM1,CNTN1,ERBB4,HPSE2,FUT9,GPC5,NRXN1,NKAIN3,SLC1A2,NFIA,DTNA,RBMS3,CTNND2,LRP1B,MAGI2,TNC,CPE,PPP2R2B,LSAMP,TNIK,ANK2,RYR3,CDH20,GFAP,RORA
2.074e-03	-6.18	response to stimulus	biological process	GO:0050896	7803	32	18204	50	PITPNC1,APOE,CLU,CTNND2,GFAP,NFIA,PLCB1,TNIK,SOX5,CPE,CNTN1,RGS6,CTNNA2,NTRK2,ADCY2,ANK2,PARD3,NRG3,RYR3,TNC,SLC1A2,SORBS1,GPM6A,RBMS3,NRXN1,PRKG1,MAPK10,RORA,FMN2,MAGI2,DTNA,ERBB4
2.084e-03	-6.17	skin-upper_back-malignant_melanoma	COSMIC cancer mutations	skin-upper_back-malignant_melanoma	319	5	16828	48	CADM2,FUT9,ERBB4,CNTN1,GPC5
2.095e-03	-6.17	high-density lipoprotein particle	cellular component	GO:0034364	26	2	19108	50	APOE,CLU
2.160e-03	-6.14	regulation of cell migration	biological process	GO:0030334	1061	9	18204	50	PRKG1,FUT9,ERBB4,CTNNA2,APOE,PLCB1,TNC,MAGI2,NRG3
2.181e-03	-6.13	KCNJ12 (potassium inwardly rectifying channel subfamily J member 12)	protein interactions	3768	27	2	19454	50	DTNA,ABLIM1
2.200e-03	-6.12	haematopoietic_and_lymphoid_tissue-spleen-lymphoid_neoplasm-marginal_zone_lymphoma	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue-spleen-lymphoid_neoplasm-marginal_zone_lymphoma	323	5	16828	48	PTPRZ1,ADCY2,NTM,SORBS1,LRP1B
2.215e-03	-6.11	SHC1 events in ERBB2 signaling	REACTOME pathways	R-HSA-1250196	22	2	10285	33	ERBB4,NRG3
2.238e-03	-6.10	modulation of chemical synaptic transmission	biological process	GO:0050804	494	6	18204	50	PLCB1,APOE,NRXN1,NTRK2,GFAP,NRG3
2.253e-03	-6.10	breast-carcinoma-ductal_carcinoma	COSMIC cancer mutations	breast-carcinoma-ductal_carcinoma	14824	48	16828	48	RYR3,CDH20,CPE,APOE,MAGI2,PPP2R2B,NFIA,RBMS3,NRXN1,SLC1A2,FUT9,HPSE2,SORBS1,NEBL,CNTN1,ABLIM1,NRG3,MGAT4C,PCDH9,GFAP,RGS6,RORA,TNC,GPM6A,LRP1B,ANK2,TNIK,LSAMP,DTNA,CLU,CTNND2,NKAIN3,GPC5,CADM2,PITPNC1,ERBB4,TRPM3,FMN2,NTRK2,PRKG1,GLIS3,PTPRZ1,SOX5,NTM,PLCB1,PARD3,ADCY2,NPAS3
2.261e-03	-6.09	regulation of trans-synaptic signaling	biological process	GO:0099177	495	6	18204	50	NTRK2,PLCB1,APOE,NRXN1,NRG3,GFAP
2.281e-03	-6.08	extrinsic component of plasma membrane	cellular component	GO:0019897	100	3	19108	50	DTNA,CTNNA2,CDH20
2.304e-03	-6.07	central nervous system myelination	biological process	GO:0022010	26	2	18204	50	CLU,CNTN1
2.304e-03	-6.07	C4-dicarboxylate transport	biological process	GO:0015740	26	2	18204	50	SLC1A2,GFAP
2.304e-03	-6.07	axon ensheathment in central nervous system	biological process	GO:0032291	26	2	18204	50	CLU,CNTN1
2.321e-03	-6.07	GFAP (glial fibrillary acidic protein)	protein interactions	2670	217	4	19454	50	NKAIN3,ABLIM1,GFAP,RORA
2.345e-03	-6.06	LRRC7 (leucine rich repeat containing 7)	protein interactions	57554	28	2	19454	50	ERBB4,CTNND2
2.351e-03	-6.05	upper_back	COSMIC cancer mutations	upper_back	328	5	16828	48	GPC5,ERBB4,CNTN1,FUT9,CADM2
2.399e-03	-6.03	calcium ion transmembrane transport	biological process	GO:0070588	205	4	18204	50	GPM6A,PLCB1,TRPM3,RYR3
2.414e-03	-6.03	skin-ankle-malignant_melanoma-acral_lentiginous	COSMIC cancer mutations	skin-ankle-malignant_melanoma-acral_lentiginous	330	5	16828	48	PARD3,CADM2,NRG3,ERBB4,PLCB1
2.424e-03	-6.02	HUNK (hormonally up-regulated Neu-associated kinase)	protein interactions	30811	104	3	19454	50	SORBS1,ABLIM1,CLU
2.446e-03	-6.01	marginal_zone_lymphoma	COSMIC cancer mutations	marginal_zone_lymphoma	331	5	16828	48	NTM,PTPRZ1,ADCY2,LRP1B,SORBS1
2.455e-03	-6.01	NTRK3 (neurotrophic receptor tyrosine kinase 3)	protein interactions	4916	367	5	19454	50	NTRK2,TNIK,CLU,PARD3,ABLIM1
2.484e-03	-6.00	axis elongation	biological process	GO:0003401	27	2	18204	50	MAGI2,TNC
2.511e-03	-5.99	IGc2	smart domains	SM00408	239	5	9717	39	NTM,NTRK2,CNTN1,CADM2,LSAMP
2.514e-03	-5.99	PLEKHA6 (pleckstrin homology domain containing A6)	protein interactions	22874	29	2	19454	50	APOE,PARD3
2.520e-03	-5.98	PSEN1 (presenilin 1)	protein interactions	5663	222	4	19454	50	DTNA,APOE,GFAP,CTNND2
2.536e-03	-5.98	acute_lymphoblastic_leukaemia	COSMIC cancer mutations	acute_lymphoblastic_leukaemia	2197	14	16828	48	GFAP,RGS6,ANK2,ERBB4,TNIK,MAGI2,LRP1B,PTPRZ1,SOX5,NTRK2,PRKG1,DTNA,NFIA,ADCY2
2.563e-03	-5.97	skin-upper_leg-malignant_melanoma	COSMIC cancer mutations	skin-upper_leg-malignant_melanoma	850	8	16828	48	PCDH9,FMN2,ANK2,ERBB4,NFIA,GLIS3,PLCB1,FUT9
2.569e-03	-5.96	PROKAR_LIPOPROTEIN	prosite domains	PS51257	76	3	12186	44	APOE,GLIS3,CPE
2.570e-03	-5.96	Bdnf (brain derived neurotrophic factor)	protein interactions	12064	1	1	19454	50	NTRK2
2.570e-03	-5.96	Cntnap2 (contactin associated protein-like 2)	protein interactions	66797	1	1	19454	50	CNTN1
2.570e-03	-5.96	Itga7 (integrin subunit alpha 7)	protein interactions	81008	1	1	19454	50	TNC
2.570e-03	-5.96	IML3 (Iml3p)	protein interactions	852404	1	1	19454	50	GFAP
2.570e-03	-5.96	Isl1 (ISL1 transcription factor, LIM/homeodomain)	protein interactions	16392	1	1	19454	50	GLIS3
2.570e-03	-5.96	Hipk3 (homeodomain interacting protein kinase 3)	protein interactions	15259	1	1	19454	50	GLIS3
2.570e-03	-5.96	App (amyloid beta precursor protein)	protein interactions	100689222	1	1	19454	50	LRP1B
2.570e-03	-5.96	Sytl1 (synaptotagmin-like 1)	protein interactions	269589	1	1	19454	50	NRXN1
2.570e-03	-5.96	Agtrap (angiotensin II, type I receptor-associated protein)	protein interactions	11610	1	1	19454	50	PITPNC1
2.570e-03	-5.96	Dynlt1 (dynein light chain Tctex-type 1)	protein interactions	83462	1	1	19454	50	NTRK2
2.590e-03	-5.96	neuron to neuron synapse	cellular component	GO:0098984	365	5	19108	50	NTRK2,TNIK,CTNND2,MAGI2,ERBB4
2.617e-03	-5.95	perinuclear endoplasmic reticulum lumen	cellular component	GO:0099020	1	1	19108	50	CLU
2.653e-03	-5.93	brain-derived neurotrophic factor receptor activity	molecular function	GO:0060175	1	1	18094	48	NTRK2
2.653e-03	-5.93	metal chelating activity	molecular function	GO:0046911	1	1	18094	48	APOE
2.673e-03	-5.92	lipoprotein particle receptor binding	molecular function	GO:0070325	29	2	18094	48	CLU,APOE
2.677e-03	-5.92	central_nervous_system-brainstem-glioma	COSMIC cancer mutations	central_nervous_system-brainstem-glioma	338	5	16828	48	HPSE2,GPC5,ERBB4,LRP1B,TNC
2.697e-03	-5.92	PKcGMP_CC	pfam domains	PF16808	1	1	17795	48	PRKG1
2.700e-03	-5.91	Contactin-1_Ig6	interpro domains	IPR047101	1	1	18521	50	CNTN1
2.700e-03	-5.91	SORBS1_SH3	interpro domains	IPR035606	1	1	18521	50	SORBS1
2.700e-03	-5.91	PKcGMP_CC	interpro domains	IPR031831	1	1	18521	50	PRKG1
2.700e-03	-5.91	NTRK2	interpro domains	IPR020455	1	1	18521	50	NTRK2
2.700e-03	-5.91	Contactin-1_Ig3	interpro domains	IPR047100	1	1	18521	50	CNTN1
2.700e-03	-5.91	Clusterin	interpro domains	IPR016016	1	1	18521	50	CLU
2.700e-03	-5.91	SORBS1_SH3_1	interpro domains	IPR035610	1	1	18521	50	SORBS1
2.700e-03	-5.91	RGS6_RGS	interpro domains	IPR037956	1	1	18521	50	RGS6
2.700e-03	-5.91	Nebulette_SH3	interpro domains	IPR035631	1	1	18521	50	NEBL
2.700e-03	-5.91	Contactin-1_Ig1	interpro domains	IPR036992	1	1	18521	50	CNTN1
2.700e-03	-5.91	Clusterin_CS	interpro domains	IPR033986	1	1	18521	50	CLU
2.700e-03	-5.91	RBMS3_RRM2	interpro domains	IPR034406	1	1	18521	50	RBMS3
2.700e-03	-5.91	PLC-beta1_EF	interpro domains	IPR028400	1	1	18521	50	PLCB1
2.700e-03	-5.91	SORBS1_SH3_2	interpro domains	IPR035611	1	1	18521	50	SORBS1
2.700e-03	-5.91	M14_CPE_CPD	interpro domains	IPR034232	1	1	18521	50	CPE
2.747e-03	-5.90	positive regulation of CD24 production	biological process	GO:2000560	1	1	18204	50	PLCB1
2.747e-03	-5.90	trans-synaptic signaling by neuropeptide	biological process	GO:0099540	1	1	18204	50	NTRK2
2.747e-03	-5.90	regulation of transport across blood-brain barrier	biological process	GO:0150200	1	1	18204	50	APOE
2.747e-03	-5.90	regulation of lipid transport across blood-brain barrier	biological process	GO:1903000	1	1	18204	50	APOE
2.747e-03	-5.90	response to glyceraldehyde	biological process	GO:1905630	1	1	18204	50	PLCB1
2.747e-03	-5.90	trans-synaptic signaling by neuropeptide, modulating synaptic transmission	biological process	GO:0099551	1	1	18204	50	NTRK2
2.747e-03	-5.90	positive regulation of transport across blood-brain barrier	biological process	GO:0150201	1	1	18204	50	APOE
2.747e-03	-5.90	regulation of heparan sulfate proteoglycan binding	biological process	GO:1905858	1	1	18204	50	APOE
2.747e-03	-5.90	regulation of neuronal signal transduction	biological process	GO:1902847	1	1	18204	50	CLU
2.747e-03	-5.90	positive regulation of lipid transport across blood-brain barrier	biological process	GO:1903002	1	1	18204	50	APOE
2.747e-03	-5.90	cellular response to glyceraldehyde	biological process	GO:1905631	1	1	18204	50	PLCB1
2.747e-03	-5.90	homologous chromosome movement towards spindle pole in meiosis I anaphase	biological process	GO:0051758	1	1	18204	50	FMN2
2.747e-03	-5.90	positive regulation of neurofibrillary tangle assembly	biological process	GO:1902998	1	1	18204	50	CLU
2.747e-03	-5.90	directional guidance of interneurons involved in migration from the subpallium to the cortex	biological process	GO:0021840	1	1	18204	50	NRG3
2.747e-03	-5.90	Lewis x epitope biosynthetic process	biological process	GO:0106402	1	1	18204	50	FUT9
2.747e-03	-5.90	intermediate-density lipoprotein particle clearance	biological process	GO:0071831	1	1	18204	50	APOE
2.747e-03	-5.90	regulation of CD24 production	biological process	GO:2000559	1	1	18204	50	PLCB1
2.747e-03	-5.90	positive regulation of heparan sulfate proteoglycan binding	biological process	GO:1905860	1	1	18204	50	APOE
2.747e-03	-5.90	regulation of cellular response to very-low-density lipoprotein particle stimulus	biological process	GO:1905890	1	1	18204	50	APOE
2.747e-03	-5.90	chemorepulsion involved in interneuron migration from the subpallium to the cortex	biological process	GO:0021842	1	1	18204	50	NRG3
2.777e-03	-5.89	cell motility	biological process	GO:0048870	1101	9	18204	50	FMN2,NRG3,GPC5,NTRK2,PRKG1,CDH20,CTNNA2,ERBB4,GPM6A
2.843e-03	-5.86	cerebellum development	biological process	GO:0021549	103	3	18204	50	PRKG1,CNTN1,RORA
2.863e-03	-5.86	myelination in peripheral nervous system	biological process	GO:0022011	29	2	18204	50	PARD3,NTRK2
2.863e-03	-5.86	neurotrophin signaling pathway	biological process	GO:0038179	29	2	18204	50	NTRK2,MAGI2
2.863e-03	-5.86	cGMP-mediated signaling	biological process	GO:0019934	29	2	18204	50	APOE,PRKG1
2.863e-03	-5.86	postsynaptic membrane organization	biological process	GO:0001941	29	2	18204	50	NRXN1,APOE
2.863e-03	-5.86	peripheral nervous system axon ensheathment	biological process	GO:0032292	29	2	18204	50	NTRK2,PARD3
2.870e-03	-5.85	SH2B1 (SH2B adaptor protein 1)	protein interactions	25970	31	2	19454	50	ERBB4,NTRK2
2.870e-03	-5.85	SH2D1B (SH2 domain containing 1B)	protein interactions	117157	31	2	19454	50	ABLIM1,ERBB4
2.918e-03	-5.84	rhabdomyosarcoma	COSMIC cancer mutations	rhabdomyosarcoma	4150	21	16828	48	CTNND2,CLU,PTPRZ1,GLIS3,NFIA,NPAS3,ADCY2,PARD3,RORA,RGS6,CDH20,RYR3,FMN2,TRPM3,PPP2R2B,ANK2,LRP1B,MAGI2,SORBS1,APOE,TNC
2.922e-03	-5.84	regulation of steroid metabolic process	biological process	GO:0019218	104	3	18204	50	APOE,RORA,PRKG1
2.952e-03	-5.83	Adherens junction	KEGG pathways	hsa04520	72	3	7161	29	CTNNA2,SORBS1,PARD3
2.952e-03	-5.83	Adherens junction	KEGG pathways	ko04520	72	3	7161	29	CTNNA2,SORBS1,PARD3
2.973e-03	-5.82	catenin complex	cellular component	GO:0016342	31	2	19108	50	CTNNA2,CDH20
3.002e-03	-5.81	neural precursor cell proliferation	biological process	GO:0061351	105	3	18204	50	RORA,SOX5,NFIA
3.017e-03	-5.80	skin-ear-carcinoma-squamous_cell_carcinoma	COSMIC cancer mutations	skin-ear-carcinoma-squamous_cell_carcinoma	506	6	16828	48	ANK2,NPAS3,MGAT4C,TNC,PRKG1,MAGI2
3.029e-03	-5.80	response to growth factor	biological process	GO:0070848	525	6	18204	50	TNC,MAGI2,NTRK2,NFIA,ERBB4,SOX5
3.041e-03	-5.80	-	gene3d domains	6.10.250.880	1	1	14470	44	ERBB4
3.057e-03	-5.79	NXPH2 (neurexophilin 2)	protein interactions	11249	32	2	19454	50	NRXN1,PCDH9
3.060e-03	-5.79	Ig-like_fold	interpro domains	IPR013783	721	7	18521	50	PTPRZ1,TNC,NTRK2,NTM,CADM2,LSAMP,CNTN1
3.062e-03	-5.79	neuron projection regeneration	biological process	GO:0031102	30	2	18204	50	GFAP,TNC
3.093e-03	-5.78	MARK3 (microtubule affinity regulating kinase 3)	protein interactions	4140	235	4	19454	50	DTNA,PARD3,NTRK2,PPP2R2B
3.099e-03	-5.78	structural constituent of cytoskeleton	molecular function	GO:0005200	110	3	18094	48	CTNNA2,ANK2,GFAP
3.145e-03	-5.76	large_intestine-caecum-carcinoma-adenocarcinoma	COSMIC cancer mutations	large_intestine-caecum-carcinoma-adenocarcinoma	14236	47	16828	48	CADM2,PITPNC1,ERBB4,FMN2,TRPM3,GPC5,PARD3,NPAS3,ADCY2,PRKG1,NTRK2,GLIS3,NTM,SOX5,PTPRZ1,PLCB1,TNC,LRP1B,GPM6A,TNIK,ANK2,LSAMP,RGS6,GFAP,RORA,NKAIN3,DTNA,CLU,CTNND2,NEBL,SORBS1,ABLIM1,CNTN1,FUT9,HPSE2,PCDH9,NRG3,MGAT4C,CPE,APOE,MAGI2,PPP2R2B,CDH20,RYR3,NRXN1,SLC1A2,NFIA
3.152e-03	-5.76	regulation of cell motility	biological process	GO:2000145	1122	9	18204	50	APOE,PLCB1,MAGI2,TNC,NRG3,PRKG1,CTNNA2,ERBB4,FUT9
3.152e-03	-5.76	positive regulation of cellular component organization	biological process	GO:0051130	1122	9	18204	50	FUT9,NRXN1,CNTN1,GPM6A,CLU,MAGI2,APOE,PLCB1,NTRK2
3.175e-03	-5.75	upper_leg	COSMIC cancer mutations	upper_leg	880	8	16828	48	ERBB4,ANK2,FMN2,PCDH9,PLCB1,FUT9,GLIS3,NFIA
3.188e-03	-5.75	CLU (clusterin)	protein interactions	1191	237	4	19454	50	CLU,LRP1B,TNIK,TNC
3.220e-03	-5.74	haematopoietic_and_lymphoid_tissue-haematopoietic_neoplasm-acute_myeloid_leukaemia	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue-haematopoietic_neoplasm-acute_myeloid_leukaemia	10418	39	16828	48	FMN2,TRPM3,ABLIM1,CNTN1,ERBB4,NEBL,CADM2,HPSE2,GPC5,NPAS3,ADCY2,PCDH9,PARD3,PLCB1,SOX5,NTM,PTPRZ1,GLIS3,NRG3,PRKG1,NTRK2,LSAMP,PPP2R2B,TNIK,ANK2,LRP1B,MAGI2,TNC,CPE,RORA,CDH20,RYR3,GFAP,SLC1A2,NRXN1,NKAIN3,RBMS3,CTNND2,NFIA
3.220e-03	-5.74	acute_myeloid_leukaemia	COSMIC cancer mutations	acute_myeloid_leukaemia	10418	39	16828	48	ANK2,TNIK,PPP2R2B,LSAMP,CPE,TNC,MAGI2,LRP1B,RORA,GFAP,CDH20,RYR3,SLC1A2,NKAIN3,NRXN1,CTNND2,RBMS3,NFIA,CNTN1,ERBB4,ABLIM1,TRPM3,FMN2,CADM2,NEBL,GPC5,HPSE2,ADCY2,NPAS3,PARD3,PCDH9,PTPRZ1,SOX5,NTM,PLCB1,NTRK2,PRKG1,NRG3,GLIS3
3.249e-03	-5.73	TRPC3 (transient receptor potential cation channel subfamily C member 3)	protein interactions	7222	33	2	19454	50	PRKG1,PLCB1
3.249e-03	-5.73	VLDLR (very low density lipoprotein receptor)	protein interactions	7436	33	2	19454	50	APOE,CLU
3.253e-03	-5.73	extracellular matrix	cellular component	GO:0031012	559	6	19108	50	PTPRZ1,GPC5,HPSE2,CLU,APOE,TNC
3.259e-03	-5.73	caecum	COSMIC cancer mutations	caecum	14248	47	16828	48	FUT9,HPSE2,CNTN1,ABLIM1,SORBS1,NEBL,MGAT4C,NRG3,PCDH9,RYR3,CDH20,PPP2R2B,CPE,MAGI2,APOE,NFIA,SLC1A2,NRXN1,GPC5,ERBB4,TRPM3,FMN2,CADM2,PITPNC1,PTPRZ1,SOX5,NTM,PLCB1,NTRK2,PRKG1,GLIS3,ADCY2,NPAS3,PARD3,RORA,GFAP,RGS6,ANK2,TNIK,LSAMP,TNC,GPM6A,LRP1B,CLU,CTNND2,DTNA,NKAIN3
3.282e-03	-5.72	external encapsulating structure	cellular component	GO:0030312	560	6	19108	50	GPC5,APOE,PTPRZ1,TNC,CLU,HPSE2
3.336e-03	-5.70	postsynapse organization	biological process	GO:0099173	109	3	18204	50	APOE,CTNND2,NRXN1
3.446e-03	-5.67	PTPRZ1 (protein tyrosine phosphatase receptor type Z1)	protein interactions	5803	34	2	19454	50	PTPRZ1,CNTN1
3.465e-03	-5.67	CEACAM8 (CEA cell adhesion molecule 8)	protein interactions	1088	118	3	19454	50	CPE,APOE,CLU
3.485e-03	-5.66	seminoma	COSMIC cancer mutations	seminoma	700	7	16828	48	NTRK2,PRKG1,RGS6,ANK2,ERBB4,CNTN1,TNIK
3.519e-03	-5.65	EGF-like_dom	interpro domains	IPR000742	232	4	18521	50	NRXN1,LRP1B,NRG3,TNC
3.548e-03	-5.64	HLA-DPA1 (major histocompatibility complex, class II, DP alpha 1)	protein interactions	3113	119	3	19454	50	CLU,PCDH9,APOE
3.611e-03	-5.62	CLUSTERIN_2	prosite domains	PS00493	1	1	12186	44	CLU
3.611e-03	-5.62	CLUSTERIN_1	prosite domains	PS00492	1	1	12186	44	CLU
3.652e-03	-5.61	circulatory system development	biological process	GO:0072359	933	8	18204	50	ERBB4,PRKG1,CPE,ANK2,NEBL,NTRK2,RORA,APOE
3.688e-03	-5.60	calcium channel activity	molecular function	GO:0005262	117	3	18094	48	TRPM3,GPM6A,RYR3
3.692e-03	-5.60	dendrite development	biological process	GO:0016358	113	3	18204	50	CTNND2,CTNNA2,PRKG1
3.692e-03	-5.60	metencephalon development	biological process	GO:0022037	113	3	18204	50	PRKG1,RORA,CNTN1
3.709e-03	-5.60	striated_muscle	COSMIC cancer mutations	striated_muscle	4228	21	16828	48	RGS6,RYR3,CDH20,RORA,LRP1B,SORBS1,APOE,MAGI2,TNC,FMN2,TRPM3,PPP2R2B,ANK2,NFIA,GLIS3,CTNND2,CLU,PTPRZ1,PARD3,NPAS3,ADCY2
3.785e-03	-5.58	regulation of circadian rhythm	biological process	GO:0042752	114	3	18204	50	PRKG1,MAPK10,RORA
3.827e-03	-5.57	negative regulation of cell migration	biological process	GO:0030336	381	5	18204	50	APOE,PLCB1,PRKG1,MAGI2,NRG3
3.828e-03	-5.57	cellular response to stimulus	biological process	GO:0051716	6307	27	18204	50	ERBB4,RORA,MAPK10,MAGI2,DTNA,FMN2,SLC1A2,SORBS1,PRKG1,ADCY2,NTRK2,TNC,RYR3,PARD3,NRG3,ANK2,CNTN1,RGS6,CPE,PLCB1,TNIK,CTNND2,NFIA,GFAP,APOE,PITPNC1,CLU
3.857e-03	-5.56	PTPRB (protein tyrosine phosphatase receptor type B)	protein interactions	5787	36	2	19454	50	TNC,CNTN1
3.897e-03	-5.55	regulation of transport	biological process	GO:0051049	1621	11	18204	50	CLU,ANK2,APOE,PRKG1,GFAP,SORBS1,SLC1A2,MAGI2,NKAIN3,PLCB1,CNTN1
3.904e-03	-5.55	functioning	COSMIC cancer mutations	functioning	1803	12	16828	48	SOX5,PTPRZ1,NTRK2,NRG3,SLC1A2,PCDH9,HPSE2,ANK2,CNTN1,FMN2,TRPM3,MAGI2
3.904e-03	-5.55	adrenal_gland-adrenal_gland-adrenal_cortical_carcinoma-functioning	COSMIC cancer mutations	adrenal_gland-adrenal_gland-adrenal_cortical_carcinoma-functioning	1803	12	16828	48	HPSE2,FMN2,TRPM3,ANK2,CNTN1,MAGI2,SOX5,PTPRZ1,NRG3,NTRK2,SLC1A2,PCDH9
3.969e-03	-5.53	NCK2 (NCK adaptor protein 2)	protein interactions	8440	252	4	19454	50	ERBB4,SORBS1,TNIK,NTRK2
3.994e-03	-5.52	lipoprotein particle	cellular component	GO:1990777	36	2	19108	50	CLU,APOE
3.994e-03	-5.52	plasma lipoprotein particle	cellular component	GO:0034358	36	2	19108	50	APOE,CLU
4.025e-03	-5.52	regulation of locomotion	biological process	GO:0040012	1164	9	18204	50	APOE,PLCB1,TNC,MAGI2,NRG3,PRKG1,CTNNA2,ERBB4,FUT9
4.052e-03	-5.51	cervix-carcinoma-squamous_cell_carcinoma	COSMIC cancer mutations	cervix-carcinoma-squamous_cell_carcinoma	11789	42	16828	48	FUT9,HPSE2,GPC5,NEBL,PITPNC1,SORBS1,FMN2,TRPM3,ABLIM1,ERBB4,CNTN1,GLIS3,NRG3,PRKG1,NTRK2,PLCB1,MGAT4C,SOX5,NTM,PTPRZ1,PCDH9,PARD3,NPAS3,ADCY2,CDH20,RGS6,RYR3,RORA,LRP1B,MAGI2,GPM6A,CPE,TNC,PPP2R2B,LSAMP,TNIK,ANK2,NFIA,DTNA,CTNND2,NRXN1,SLC1A2
4.068e-03	-5.50	large_intestine-caecum-adenoma	COSMIC cancer mutations	large_intestine-caecum-adenoma	229	4	16828	48	LRP1B,ERBB4,CTNND2,HPSE2
4.071e-03	-5.50	CTNND2 (catenin delta 2)	protein interactions	1501	37	2	19454	50	MAGI2,CTNND2
4.093e-03	-5.50	cervix	COSMIC cancer mutations	cervix	11793	42	16828	48	NEBL,SORBS1,PITPNC1,ABLIM1,ERBB4,CNTN1,FMN2,TRPM3,GPC5,HPSE2,FUT9,PCDH9,PARD3,NPAS3,ADCY2,PRKG1,NTRK2,GLIS3,NRG3,NTM,SOX5,PTPRZ1,PLCB1,MGAT4C,CPE,TNC,LRP1B,GPM6A,MAGI2,TNIK,ANK2,LSAMP,PPP2R2B,CDH20,RGS6,RYR3,RORA,NRXN1,SLC1A2,DTNA,NFIA,CTNND2
4.102e-03	-5.50	Ig_sub	interpro domains	IPR003599	394	5	18521	50	NTM,NTRK2,CADM2,LSAMP,CNTN1
4.106e-03	-5.50	Downregulation of ERBB2 signaling	REACTOME pathways	R-HSA-8863795	30	2	10285	33	ERBB4,NRG3
4.112e-03	-5.49	FYN (FYN proto-oncogene, Src family tyrosine kinase)	protein interactions	2534	414	5	19454	50	ERBB4,PTPRZ1,CTNND2,NTRK2,CNTN1
4.161e-03	-5.48	cytoskeletal protein binding	molecular function	GO:0008092	989	8	18094	48	FMN2,ABLIM1,CLU,NEBL,APOE,ANK2,SORBS1,CTNNA2
4.196e-03	-5.47	central_nervous_system-brainstem-glioma-oligoastrocytoma_Grade_III	COSMIC cancer mutations	central_nervous_system-brainstem-glioma-oligoastrocytoma_Grade_III	114	3	16828	48	RYR3,SOX5,SLC1A2
4.215e-03	-5.47	glial cell projection	cellular component	GO:0097386	37	2	19108	50	GFAP,SLC1A2
4.257e-03	-5.46	response to endogenous stimulus	biological process	GO:0009719	1402	10	18204	50	RYR3,TNC,MAGI2,PLCB1,NTRK2,NFIA,ERBB4,SOX5,SLC1A2,SORBS1
4.258e-03	-5.46	EPB41L4A (erythrocyte membrane protein band 4.1 like 4A)	protein interactions	64097	127	3	19454	50	DTNA,ABLIM1,PARD3
4.290e-03	-5.45	MMP3 (matrix metallopeptidase 3)	protein interactions	4314	38	2	19454	50	APOE,CLU
4.290e-03	-5.45	RORA (RAR related orphan receptor A)	protein interactions	6095	38	2	19454	50	RORA,GFAP
4.316e-03	-5.45	env (Envelope surface glycoprotein gp160, precursor)	protein interactions	155971	1501	10	19454	50	SLC1A2,CTNNA2,TNC,ADCY2,PLCB1,MGAT4C,GFAP,MAPK10,NTRK2,APOE
4.370e-03	-5.43	striated muscle contraction	biological process	GO:0006941	120	3	18204	50	ANK2,RYR3,DTNA
4.400e-03	-5.43	NTKRECEPTOR2	prints domains	PR01941	1	1	5227	23	NTRK2
4.506e-03	-5.40	negative regulation of cell motility	biological process	GO:2000146	396	5	18204	50	NRG3,PRKG1,MAGI2,PLCB1,APOE
4.515e-03	-5.40	E (envelope protein)	protein interactions	14254599	39	2	19454	50	MAGI2,PARD3
4.590e-03	-5.38	lung-middle_lobe-carcinoma-adenocarcinoma	COSMIC cancer mutations	lung-middle_lobe-carcinoma-adenocarcinoma	1368	10	16828	48	TRPM3,ANK2,ERBB4,MAGI2,LRP1B,CPE,PCDH9,HPSE2,CTNND2,RYR3
4.602e-03	-5.38	FGFR1 (fibroblast growth factor receptor 1)	protein interactions	2260	611	6	19454	50	DTNA,ABLIM1,PARD3,ANK2,CLU,TNIK
4.631e-03	-5.38	positive regulation of glucose import	biological process	GO:0046326	37	2	18204	50	SLC1A2,SORBS1
4.639e-03	-5.37	haematopoietic_and_lymphoid_tissue	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue	14368	47	16828	48	MAGI2,CPE,PPP2R2B,RYR3,CDH20,NRXN1,SLC1A2,NFIA,RBMS3,SORBS1,NEBL,CNTN1,ABLIM1,HPSE2,FUT9,PCDH9,NRG3,MGAT4C,GPM6A,LRP1B,TNC,LSAMP,ANK2,TNIK,GFAP,RGS6,RORA,NKAIN3,DTNA,CLU,CTNND2,PITPNC1,CADM2,TRPM3,FMN2,ERBB4,GPC5,PARD3,ADCY2,NPAS3,GLIS3,NTRK2,PRKG1,PLCB1,PTPRZ1,SOX5,NTM
4.674e-03	-5.37	protein-lipid complex	cellular component	GO:0032994	39	2	19108	50	APOE,CLU
4.720e-03	-5.36	ErbB signaling pathway	KEGG pathways	ko04012	85	3	7161	29	MAPK10,NRG3,ERBB4
4.720e-03	-5.36	ErbB signaling pathway	KEGG pathways	hsa04012	85	3	7161	29	MAPK10,NRG3,ERBB4
4.744e-03	-5.35	CTNNBIP1 (catenin beta interacting protein 1)	protein interactions	56998	40	2	19454	50	CTNNA2,PPP2R2B
4.744e-03	-5.35	SHC2 (SHC adaptor protein 2)	protein interactions	25759	40	2	19454	50	ERBB4,NTRK2
4.744e-03	-5.35	DZIP1 (DAZ interacting zinc finger protein 1)	protein interactions	22873	40	2	19454	50	PARD3,NTRK2
4.776e-03	-5.34	Z disc	cellular component	GO:0030018	130	3	19108	50	ANK2,NEBL,RYR3
4.823e-03	-5.33	Laminin	gene3d domains	2.10.25.10	226	4	14470	44	LRP1B,NRXN1,NRG3,TNC
4.880e-03	-5.32	amino acid import across plasma membrane	biological process	GO:0089718	38	2	18204	50	GFAP,SLC1A2
4.897e-03	-5.32	cellular anatomical entity morphogenesis	biological process	GO:0032989	125	3	18204	50	ANK2,NEBL,CNTN1
4.897e-03	-5.32	cellular component assembly involved in morphogenesis	biological process	GO:0010927	125	3	18204	50	NEBL,CNTN1,ANK2
4.934e-03	-5.31	middle_lobe	COSMIC cancer mutations	middle_lobe	1382	10	16828	48	PCDH9,CPE,LRP1B,MAGI2,ERBB4,ANK2,TRPM3,RYR3,CTNND2,HPSE2
4.980e-03	-5.30	RASSF7 (Ras association domain family member 7)	protein interactions	8045	41	2	19454	50	CLU,PARD3
5.099e-03	-5.28	collagen-containing extracellular matrix	cellular component	GO:0062023	428	5	19108	50	CLU,TNC,APOE,PTPRZ1,GPC5
5.118e-03	-5.28	cell-cell junction assembly	biological process	GO:0007043	127	3	18204	50	CDH20,PARD3,ANK2
5.134e-03	-5.27	cdh11.S (cadherin 11 S homeolog)	protein interactions	100337621	2	1	19454	50	ERBB4
5.134e-03	-5.27	TRIM39-RPP21 (TRIM39-RPP21 readthrough)	protein interactions	202658	2	1	19454	50	PRKG1
5.134e-03	-5.27	Zmym2 (zinc finger, MYM-type 2)	protein interactions	76007	2	1	19454	50	GLIS3
5.134e-03	-5.27	URA1 (dihydroorotate dehydrogenase)	protein interactions	853664	2	1	19454	50	GFAP
5.134e-03	-5.27	Kdm4c (lysine (K)-specific demethylase 4C)	protein interactions	76804	2	1	19454	50	GLIS3
5.134e-03	-5.27	cellular response to alkaloid	biological process	GO:0071312	39	2	18204	50	RYR3,SLC1A2
5.134e-03	-5.27	positive regulation of nitric oxide biosynthetic process	biological process	GO:0045429	39	2	18204	50	APOE,CLU
5.157e-03	-5.27	animal organ morphogenesis	biological process	GO:0009887	988	8	18204	50	NRG3,TNC,NTRK2,CTNNA2,ERBB4,ABLIM1,SOX5,CPE
5.161e-03	-5.27	regulation of cellular component organization	biological process	GO:0051128	2455	14	18204	50	TNIK,MAGI2,PLCB1,CTNNA2,CNTN1,TNC,CLU,NRG3,APOE,NTRK2,GFAP,FUT9,NRXN1,GPM6A
5.202e-03	-5.26	Gap junction	KEGG pathways	hsa04540	88	3	7161	29	PRKG1,PLCB1,ADCY2
5.202e-03	-5.26	Gap junction	KEGG pathways	ko04540	88	3	7161	29	ADCY2,PLCB1,PRKG1
5.227e-03	-5.25	chylomicron remnant	cellular component	GO:0034360	2	1	19108	50	APOE
5.227e-03	-5.25	discoidal high-density lipoprotein particle	cellular component	GO:0034365	2	1	19108	50	APOE
5.299e-03	-5.24	type II activin receptor binding	molecular function	GO:0070699	2	1	18094	48	MAGI2
5.299e-03	-5.24	cGMP-dependent protein kinase activity	molecular function	GO:0004692	2	1	18094	48	PRKG1
5.299e-03	-5.24	heparanase activity	molecular function	GO:0030305	2	1	18094	48	HPSE2
5.331e-03	-5.23	EGF_3	prosite domains	PS50026	196	4	12186	44	LRP1B,TNC,NRG3,NRXN1
5.362e-03	-5.23	ankle	COSMIC cancer mutations	ankle	398	5	16828	48	NRG3,PARD3,CADM2,PLCB1,ERBB4
5.373e-03	-5.23	positive regulation of multicellular organismal process	biological process	GO:0051240	1691	11	18204	50	APOE,RORA,PLCB1,NTRK2,CLU,PTPRZ1,PARD3,NRXN1,SOX5,GFAP,ERBB4
5.376e-03	-5.23	negative regulation of locomotion	biological process	GO:0040013	413	5	18204	50	NRG3,PRKG1,MAGI2,PLCB1,APOE
5.388e-03	-5.22	DUF1154	pfam domains	PF06631	2	1	17795	48	PLCB1
5.388e-03	-5.22	DUF5050	pfam domains	PF16472	2	1	17795	48	LRP1B
5.388e-03	-5.22	Clusterin	pfam domains	PF01093	2	1	17795	48	CLU
5.388e-03	-5.22	MAGI_u1	pfam domains	PF16663	2	1	17795	48	MAGI2
5.388e-03	-5.22	Par3_HAL_N_term	pfam domains	PF12053	2	1	17795	48	PARD3
5.388e-03	-5.22	Glyco_hydro_79n	pfam domains	PF03662	2	1	17795	48	HPSE2
5.392e-03	-5.22	PLC-beta_CS	interpro domains	IPR009535	2	1	18521	50	PLCB1
5.392e-03	-5.22	Clusterin_C	interpro domains	IPR016015	2	1	18521	50	CLU
5.392e-03	-5.22	Distrobrevin	interpro domains	IPR017432	2	1	18521	50	DTNA
5.392e-03	-5.22	STKc_cGK	interpro domains	IPR035014	2	1	18521	50	PRKG1
5.392e-03	-5.22	Clusterin_N	interpro domains	IPR016014	2	1	18521	50	CLU
5.392e-03	-5.22	Glyco_hydro_79	interpro domains	IPR005199	2	1	18521	50	HPSE2
5.392e-03	-5.22	Contactin-1_2_Ig1	interpro domains	IPR047102	2	1	18521	50	CNTN1
5.392e-03	-5.22	Clusterin-like	interpro domains	IPR000753	2	1	18521	50	CLU
5.392e-03	-5.22	Alpha_CARP_receptor-type	interpro domains	IPR041887	2	1	18521	50	PTPRZ1
5.392e-03	-5.22	cGMP_dep_kinase	interpro domains	IPR002374	2	1	18521	50	PRKG1
5.392e-03	-5.22	Par3/HAL_N	interpro domains	IPR021922	2	1	18521	50	PARD3
5.392e-03	-5.22	LRP1-like_beta_prop	interpro domains	IPR032485	2	1	18521	50	LRP1B
5.392e-03	-5.22	Formin_Cappuccino_subfam	interpro domains	IPR001265	2	1	18521	50	FMN2
5.395e-03	-5.22	cyclic purine nucleotide metabolic process	biological process	GO:0052652	40	2	18204	50	ADCY2,RORA
5.395e-03	-5.22	positive regulation of nitric oxide metabolic process	biological process	GO:1904407	40	2	18204	50	CLU,APOE
5.405e-03	-5.22	plasma membrane region	cellular component	GO:0098590	1278	9	19108	50	PARD3,ANK2,SORBS1,SLC1A2,CNTN1,NRXN1,ERBB4,GPM6A,TNIK
5.475e-03	-5.21	NEFM (neurofilament medium chain)	protein interactions	4741	139	3	19454	50	TNIK,GFAP,APOE
5.486e-03	-5.21	regulation of neurofibrillary tangle assembly	biological process	GO:1902996	2	1	18204	50	CLU
5.486e-03	-5.21	mesenchymal-epithelial cell signaling involved in prostate gland development	biological process	GO:0060739	2	1	18204	50	TNC
5.486e-03	-5.21	negative regulation of monocyte extravasation	biological process	GO:2000438	2	1	18204	50	PLCB1
5.486e-03	-5.21	negative regulation of inositol phosphate biosynthetic process	biological process	GO:0010920	2	1	18204	50	PRKG1
5.486e-03	-5.21	phosphatidylinositol catabolic process	biological process	GO:0031161	2	1	18204	50	PLCB1
5.486e-03	-5.21	lipid transport involved in lipid storage	biological process	GO:0010877	2	1	18204	50	APOE
5.486e-03	-5.21	protein localization to M-band	biological process	GO:0036309	2	1	18204	50	ANK2
5.486e-03	-5.21	cellular response to fluoride	biological process	GO:1902618	2	1	18204	50	PLCB1
5.486e-03	-5.21	establishment of planar polarity involved in nephron morphogenesis	biological process	GO:0072046	2	1	18204	50	ERBB4
5.486e-03	-5.21	neuronal stem cell division	biological process	GO:0036445	2	1	18204	50	FUT9
5.486e-03	-5.21	protein localization to T-tubule	biological process	GO:0036371	2	1	18204	50	ANK2
5.486e-03	-5.21	activation of meiosis involved in egg activation	biological process	GO:0060466	2	1	18204	50	PLCB1
5.612e-03	-5.18	calcium ion transmembrane transporter activity	molecular function	GO:0015085	136	3	18094	48	RYR3,GPM6A,TRPM3
5.653e-03	-5.18	protein localization	biological process	GO:0008104	1954	12	18204	50	CLU,ANK2,PARD3,APOE,LRP1B,GFAP,NRXN1,FMN2,TNIK,MAGI2,ERBB4,CPE
5.662e-03	-5.17	cyclic nucleotide metabolic process	biological process	GO:0009187	41	2	18204	50	RORA,ADCY2
5.670e-03	-5.17	Immunoglobulins	gene3d domains	2.60.40.10	721	7	14470	44	TNC,CNTN1,PTPRZ1,NTM,CADM2,LSAMP,NTRK2
5.692e-03	-5.17	actin binding	molecular function	GO:0003779	434	5	18094	48	CTNNA2,SORBS1,NEBL,FMN2,ABLIM1
5.697e-03	-5.17	amino acid transport	biological process	GO:0006865	132	3	18204	50	NTRK2,SLC1A2,GFAP
5.717e-03	-5.16	SH2D1A (SH2 domain containing 1A)	protein interactions	4068	44	2	19454	50	LRP1B,ERBB4
5.720e-03	-5.16	Calcium signaling pathway	KEGG pathways	hsa04020	181	4	7161	29	ERBB4,ADCY2,RYR3,PLCB1
5.720e-03	-5.16	Calcium signaling pathway	KEGG pathways	ko04020	181	4	7161	29	ERBB4,PLCB1,RYR3,ADCY2
5.806e-03	-5.15	tau protein binding	molecular function	GO:0048156	43	2	18094	48	APOE,CLU
5.817e-03	-5.15	regulation of sequestering of calcium ion	biological process	GO:0051282	133	3	18204	50	RYR3,ANK2,PLCB1
5.840e-03	-5.14	cellular macromolecule localization	biological process	GO:0070727	1962	12	18204	50	NRXN1,GFAP,LRP1B,APOE,PARD3,ANK2,CLU,CPE,ERBB4,TNIK,FMN2,MAGI2
5.876e-03	-5.14	fn3	pfam domains	PF00041	136	3	17795	48	TNC,CNTN1,PTPRZ1
5.889e-03	-5.13	GnRH signaling pathway	KEGG pathways	hsa04912	92	3	7161	29	ADCY2,PLCB1,MAPK10
5.889e-03	-5.13	GnRH signaling pathway	KEGG pathways	ko04912	92	3	7161	29	MAPK10,PLCB1,ADCY2
5.935e-03	-5.13	Schwann cell development	biological process	GO:0014044	42	2	18204	50	NTRK2,PARD3
5.935e-03	-5.13	regulation of cellular extravasation	biological process	GO:0002691	42	2	18204	50	FUT9,PLCB1
5.935e-03	-5.13	triglyceride homeostasis	biological process	GO:0070328	42	2	18204	50	APOE,RORA
5.981e-03	-5.12	regulation of canonical Wnt signaling pathway	biological process	GO:0060828	265	4	18204	50	GPC5,APOE,CTNND2,RBMS3
5.998e-03	-5.12	developmental growth	biological process	GO:0048589	424	5	18204	50	SLC1A2,ERBB4,TNC,PRKG1,MAGI2
5.998e-03	-5.12	growth	biological process	GO:0040007	424	5	18204	50	SLC1A2,MAGI2,TNC,PRKG1,ERBB4
6.035e-03	-5.11	Ig-like_dom	interpro domains	IPR007110	432	5	18521	50	LSAMP,CNTN1,NTM,NTRK2,CADM2
6.073e-03	-5.10	-	gene3d domains	6.20.350.10	2	1	14470	44	RYR3
6.073e-03	-5.10	Vinculin, Vh2 four-helix bundle	gene3d domains	1.20.120.810	2	1	14470	44	CTNNA2
6.087e-03	-5.10	femur	COSMIC cancer mutations	femur	1197	9	16828	48	PTPRZ1,GPC5,HPSE2,NRG3,RYR3,ADCY2,FMN2,PCDH9,LRP1B
6.108e-03	-5.10	LCK (LCK proto-oncogene, Src family tyrosine kinase)	protein interactions	3932	455	5	19454	50	PARD3,ERBB4,DTNA,FMN2,CTNND2
6.117e-03	-5.10	nasopharyngeal_carcinoma	COSMIC cancer mutations	nasopharyngeal_carcinoma	1425	10	16828	48	NTRK2,NFIA,CTNND2,CLU,CADM2,PITPNC1,MAGI2,ANK2,FMN2,SLC1A2
6.117e-03	-5.10	upper_aerodigestive_tract-pharynx-carcinoma-nasopharyngeal_carcinoma	COSMIC cancer mutations	upper_aerodigestive_tract-pharynx-carcinoma-nasopharyngeal_carcinoma	1425	10	16828	48	CLU,CTNND2,NTRK2,NFIA,ANK2,SLC1A2,FMN2,CADM2,MAGI2,PITPNC1
6.190e-03	-5.08	skin-leg-malignant_melanoma-nodular	COSMIC cancer mutations	skin-leg-malignant_melanoma-nodular	258	4	16828	48	MAGI2,FMN2,CNTN1,PTPRZ1
6.190e-03	-5.08	bronchioloalveolar_adenocarcinoma	COSMIC cancer mutations	bronchioloalveolar_adenocarcinoma	778	7	16828	48	PRKG1,NTRK2,SOX5,CTNND2,TNIK,ERBB4,ADCY2
6.190e-03	-5.08	lung-carcinoma-bronchioloalveolar_adenocarcinoma	COSMIC cancer mutations	lung-carcinoma-bronchioloalveolar_adenocarcinoma	778	7	16828	48	TNIK,ADCY2,ERBB4,SOX5,CTNND2,PRKG1,NTRK2
6.213e-03	-5.08	acylglycerol homeostasis	biological process	GO:0055090	43	2	18204	50	RORA,APOE
6.234e-03	-5.08	EXTL2 (exostosin like glycosyltransferase 2)	protein interactions	2135	46	2	19454	50	CLU,MGAT4C
6.237e-03	-5.08	cell surface receptor protein tyrosine kinase signaling pathway	biological process	GO:0007169	428	5	18204	50	NRG3,ERBB4,SORBS1,NTRK2,PLCB1
6.342e-03	-5.06	I band	cellular component	GO:0031674	144	3	19108	50	ANK2,RYR3,NEBL
6.420e-03	-5.05	trans-synaptic signaling	biological process	GO:0099537	431	5	18204	50	SLC1A2,NTRK2,NRXN1,APOE,DTNA
6.441e-03	-5.04	developmental growth involved in morphogenesis	biological process	GO:0060560	138	3	18204	50	TNC,PRKG1,MAGI2
6.498e-03	-5.04	positive regulation of glucose transmembrane transport	biological process	GO:0010828	44	2	18204	50	SORBS1,SLC1A2
6.500e-03	-5.04	BDNF (brain derived neurotrophic factor)	protein interactions	627	47	2	19454	50	NTRK2,CPE
6.512e-03	-5.03	LRP2 (LDL receptor related protein 2)	protein interactions	4036	148	3	19454	50	LRP1B,CLU,APOE
6.574e-03	-5.02	actin filament-based process	biological process	GO:0030029	616	6	18204	50	ANK2,PRKG1,TNIK,FMN2,SORBS1,NEBL
6.589e-03	-5.02	cell surface receptor signaling pathway	biological process	GO:0007166	1992	12	18204	50	MAGI2,TNIK,NRG3,PLCB1,MAPK10,NTRK2,NFIA,ERBB4,CNTN1,CPE,CTNND2,SORBS1
6.634e-03	-5.02	GSE1 (Gse1 coiled-coil protein)	protein interactions	23199	149	3	19454	50	TNIK,SOX5,NFIA
6.702e-03	-5.01	clear_cell_renal_cell_carcinoma	COSMIC cancer mutations	clear_cell_renal_cell_carcinoma	13924	46	16828	48	NFIA,NRXN1,SLC1A2,CDH20,RYR3,APOE,MAGI2,CPE,PPP2R2B,NRG3,MGAT4C,PCDH9,FUT9,HPSE2,SORBS1,NEBL,CNTN1,ABLIM1,DTNA,CLU,CTNND2,NKAIN3,GFAP,RGS6,RORA,GPM6A,LRP1B,TNC,LSAMP,ANK2,TNIK,GLIS3,NTRK2,PRKG1,PLCB1,PTPRZ1,SOX5,PARD3,ADCY2,NPAS3,GPC5,PITPNC1,CADM2,TRPM3,FMN2,ERBB4
6.702e-03	-5.01	kidney-carcinoma-clear_cell_renal_cell_carcinoma	COSMIC cancer mutations	kidney-carcinoma-clear_cell_renal_cell_carcinoma	13924	46	16828	48	GLIS3,NRG3,PRKG1,NTRK2,PLCB1,MGAT4C,SOX5,PTPRZ1,PCDH9,PARD3,NPAS3,ADCY2,FUT9,HPSE2,GPC5,NEBL,PITPNC1,SORBS1,CADM2,FMN2,TRPM3,ABLIM1,ERBB4,CNTN1,NFIA,DTNA,CTNND2,CLU,NRXN1,NKAIN3,SLC1A2,RGS6,CDH20,RYR3,GFAP,RORA,LRP1B,APOE,GPM6A,MAGI2,TNC,CPE,PPP2R2B,LSAMP,TNIK,ANK2
6.772e-03	-4.99	HTRA1 (HtrA serine peptidase 1)	protein interactions	5654	48	2	19454	50	MGAT4C,APOE
6.772e-03	-4.99	PATE1 (prostate and testis expressed 1)	protein interactions	160065	48	2	19454	50	CPE,LRP1B
6.788e-03	-4.99	negative regulation of blood coagulation	biological process	GO:0030195	45	2	18204	50	APOE,PRKG1
6.788e-03	-4.99	acidic amino acid transport	biological process	GO:0015800	45	2	18204	50	SLC1A2,NTRK2
6.821e-03	-4.99	Inflammatory mediator regulation of TRP channels	KEGG pathways	hsa04750	97	3	7161	29	ADCY2,MAPK10,PLCB1
6.821e-03	-4.99	Inflammatory mediator regulation of TRP channels	KEGG pathways	ko04750	97	3	7161	29	ADCY2,PLCB1,MAPK10
6.969e-03	-4.97	neuron migration	biological process	GO:0001764	142	3	18204	50	PRKG1,GPM6A,NTRK2
6.987e-03	-4.96	skin-neck-malignant_melanoma	COSMIC cancer mutations	skin-neck-malignant_melanoma	1223	9	16828	48	TNC,LRP1B,ADCY2,ERBB4,CNTN1,TRPM3,CTNND2,GPC5,PLCB1
7.053e-03	-4.95	abdomen	COSMIC cancer mutations	abdomen	603	6	16828	48	LRP1B,FMN2,FUT9,CTNND2,ERBB4,ANK2
7.084e-03	-4.95	regulation of myelination	biological process	GO:0031641	46	2	18204	50	PTPRZ1,PARD3
7.084e-03	-4.95	negative regulation of hemostasis	biological process	GO:1900047	46	2	18204	50	PRKG1,APOE
7.097e-03	-4.95	apical junction complex	cellular component	GO:0043296	150	3	19108	50	MAGI2,SORBS1,PARD3
7.213e-03	-4.93	system process	biological process	GO:0003008	2015	12	18204	50	NTRK2,APOE,PLCB1,ANK2,RYR3,PTPRZ1,DTNA,SLC1A2,NRXN1,CTNNA2,ABLIM1,PRKG1
7.284e-03	-4.92	neck	COSMIC cancer mutations	neck	1231	9	16828	48	CTNND2,GPC5,PLCB1,TNC,LRP1B,CNTN1,ERBB4,ADCY2,TRPM3
7.386e-03	-4.91	Schwann cell differentiation	biological process	GO:0014037	47	2	18204	50	PARD3,NTRK2
7.386e-03	-4.91	regulation of neuron migration	biological process	GO:2001222	47	2	18204	50	CTNNA2,NRG3
7.485e-03	-4.89	calcium channel regulator activity	molecular function	GO:0005246	49	2	18094	48	PRKG1,NRXN1
7.515e-03	-4.89	Wnt signaling pathway	biological process	GO:0016055	283	4	18204	50	MAGI2,TNIK,CPE,CTNND2
7.525e-03	-4.89	CEP19 (centrosomal protein 19)	protein interactions	84984	156	3	19454	50	ABLIM1,FMN2,PARD3
7.617e-03	-4.88	FAM171B (family with sequence similarity 171 member B)	protein interactions	165215	51	2	19454	50	PARD3,NTRK2
7.626e-03	-4.88	Retrograde endocannabinoid signaling	KEGG pathways	hsa04723	101	3	7161	29	MAPK10,PLCB1,ADCY2
7.626e-03	-4.88	Retrograde endocannabinoid signaling	KEGG pathways	ko04723	101	3	7161	29	PLCB1,MAPK10,ADCY2
7.691e-03	-4.87	Lep (leptin)	protein interactions	16846	3	1	19454	50	CLU
7.691e-03	-4.87	Spop (speckle-type BTB/POZ protein)	protein interactions	20747	3	1	19454	50	GLIS3
7.691e-03	-4.87	IL34 (interleukin 34)	protein interactions	146433	3	1	19454	50	PTPRZ1
7.691e-03	-4.87	Itgb1 (integrin subunit beta 1)	protein interactions	24511	3	1	19454	50	TNC
7.691e-03	-4.87	TULP1 (TUB like protein 1)	protein interactions	7287	3	1	19454	50	NRXN1
7.691e-03	-4.87	QRFPR (pyroglutamylated RFamide peptide receptor)	protein interactions	84109	3	1	19454	50	NTM
7.691e-03	-4.87	BCO1 (beta-carotene oxygenase 1)	protein interactions	53630	3	1	19454	50	ABLIM1
7.691e-03	-4.87	NRG3 (neuregulin 3)	protein interactions	10718	3	1	19454	50	ERBB4
7.746e-03	-4.86	cytoskeleton	cellular component	GO:0005856	2412	13	19108	50	ABLIM1,PPP2R2B,DTNA,SORBS1,NEBL,FMN2,TNIK,CLU,CTNNA2,ANK2,PARD3,GFAP,MAGI2
7.836e-03	-4.85	Chagas disease (American trypanosomiasis)	KEGG pathways	hsa05142	102	3	7161	29	PPP2R2B,PLCB1,MAPK10
7.836e-03	-4.85	Chagas disease (American trypanosomiasis)	KEGG pathways	ko05142	102	3	7161	29	MAPK10,PLCB1,PPP2R2B
7.909e-03	-4.84	SNAP91 (synaptosome associated protein 91)	protein interactions	9892	52	2	19454	50	ERBB4,GPM6A
7.938e-03	-4.84	alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity	molecular function	GO:0008454	3	1	18094	48	MGAT4C
7.938e-03	-4.84	neuregulin receptor activity	molecular function	GO:0038131	3	1	18094	48	ERBB4
7.938e-03	-4.84	JUN kinase activity	molecular function	GO:0004705	3	1	18094	48	MAPK10
7.938e-03	-4.84	epidermal growth factor receptor activity	molecular function	GO:0005006	3	1	18094	48	ERBB4
7.938e-03	-4.84	cysteine transmembrane transporter activity	molecular function	GO:0033229	3	1	18094	48	SLC1A2
7.938e-03	-4.84	beta-1 adrenergic receptor binding	molecular function	GO:0031697	3	1	18094	48	MAGI2
8.007e-03	-4.83	negative regulation of coagulation	biological process	GO:0050819	49	2	18204	50	PRKG1,APOE
8.007e-03	-4.83	oligodendrocyte development	biological process	GO:0014003	49	2	18204	50	CNTN1,CLU
8.011e-03	-4.83	CLa	smart domains	SM00035	2	1	9717	39	CLU
8.011e-03	-4.83	CLb	smart domains	SM00030	2	1	9717	39	CLU
8.071e-03	-4.82	PLC-beta_C	pfam domains	PF08703	3	1	17795	48	PLCB1
8.071e-03	-4.82	Myelin_PLP	pfam domains	PF01275	3	1	17795	48	GPM6A
8.071e-03	-4.82	TM_ErbB1	pfam domains	PF21314	3	1	17795	48	ERBB4
8.071e-03	-4.82	RyR	pfam domains	PF02026	3	1	17795	48	RYR3
8.071e-03	-4.82	RR_TM4-6	pfam domains	PF06459	3	1	17795	48	RYR3
8.071e-03	-4.82	Sorb	pfam domains	PF02208	3	1	17795	48	SORBS1
8.071e-03	-4.82	RYDR_Jsol	pfam domains	PF21119	3	1	17795	48	RYR3
8.071e-03	-4.82	LRRCT_2	pfam domains	PF16920	3	1	17795	48	NTRK2
8.071e-03	-4.82	UPA_2	pfam domains	PF17809	3	1	17795	48	ANK2
8.078e-03	-4.82	MAPK_JNK	interpro domains	IPR008351	3	1	18521	50	MAPK10
8.078e-03	-4.82	NTRK_LRRCT	interpro domains	IPR031635	3	1	18521	50	NTRK2
8.078e-03	-4.82	SPRY3_RyR	interpro domains	IPR035762	3	1	18521	50	RYR3
8.078e-03	-4.82	PLC-beta_C	interpro domains	IPR014815	3	1	18521	50	PLCB1
8.078e-03	-4.82	SPRY2_RyR	interpro domains	IPR035764	3	1	18521	50	RYR3
8.078e-03	-4.82	NR_DBD_ROR	interpro domains	IPR044101	3	1	18521	50	RORA
8.078e-03	-4.82	Neuregulin	interpro domains	IPR040180	3	1	18521	50	NRG3
8.078e-03	-4.82	Ryan_recept	interpro domains	IPR013333	3	1	18521	50	RYR3
8.078e-03	-4.82	ROR_rcpt	interpro domains	IPR003079	3	1	18521	50	RORA
8.078e-03	-4.82	RYDR_Jsol	interpro domains	IPR048581	3	1	18521	50	RYR3
8.078e-03	-4.82	SoHo_dom	interpro domains	IPR003127	3	1	18521	50	SORBS1
8.078e-03	-4.82	Ryanodine_rcpt	interpro domains	IPR003032	3	1	18521	50	RYR3
8.078e-03	-4.82	Ankyrin_UPA	interpro domains	IPR040745	3	1	18521	50	ANK2
8.078e-03	-4.82	SPRY1_RyR	interpro domains	IPR035761	3	1	18521	50	RYR3
8.078e-03	-4.82	Ryanrecept_TM4-6	interpro domains	IPR009460	3	1	18521	50	RYR3
8.078e-03	-4.82	Myelin_PLP_CS	interpro domains	IPR018237	3	1	18521	50	GPM6A
8.078e-03	-4.82	Myelin_PLP	interpro domains	IPR001614	3	1	18521	50	GPM6A
8.078e-03	-4.82	Vinculin_CS	interpro domains	IPR000633	3	1	18521	50	CTNNA2
8.078e-03	-4.82	TM_ErbB1	interpro domains	IPR049328	3	1	18521	50	ERBB4
8.078e-03	-4.82	NTRK	interpro domains	IPR020777	3	1	18521	50	NTRK2
8.079e-03	-4.82	muscle cell differentiation	biological process	GO:0042692	289	4	18204	50	ANK2,PRKG1,NEBL,RORA
8.088e-03	-4.82	signaling receptor complex adaptor activity	molecular function	GO:0030159	51	2	18094	48	SORBS1,MAGI2
8.097e-03	-4.82	regulation of nervous system development	biological process	GO:0051960	456	5	18204	50	PTPRZ1,GFAP,PARD3,NRXN1,NTRK2
8.100e-03	-4.82	AFDN (afadin, adherens junction formation factor)	protein interactions	4301	309	4	19454	50	PARD3,DTNA,SORBS1,NRXN1
8.206e-03	-4.80	GOLGA6A (golgin A6 family member A)	protein interactions	342096	53	2	19454	50	NEBL,GFAP
8.218e-03	-4.80	cysteine transmembrane transport	biological process	GO:1903712	3	1	18204	50	SLC1A2
8.218e-03	-4.80	formin-nucleated actin cable organization	biological process	GO:0110009	3	1	18204	50	FMN2
8.218e-03	-4.80	formin-nucleated actin cable assembly	biological process	GO:0070649	3	1	18204	50	FMN2
8.218e-03	-4.80	regulation of retrograde trans-synaptic signaling by endocanabinoid	biological process	GO:0099178	3	1	18204	50	PLCB1
8.218e-03	-4.80	central nervous system morphogenesis	biological process	GO:0021551	3	1	18204	50	ERBB4
8.218e-03	-4.80	Schwann cell proliferation	biological process	GO:0014010	3	1	18204	50	GFAP
8.218e-03	-4.80	protein targeting to lysosome involved in chaperone-mediated autophagy	biological process	GO:0061740	3	1	18204	50	CLU
8.218e-03	-4.80	neuroligin clustering involved in postsynaptic membrane assembly	biological process	GO:0097118	3	1	18204	50	NRXN1
8.218e-03	-4.80	cardiac muscle thin filament assembly	biological process	GO:0071691	3	1	18204	50	NEBL
8.218e-03	-4.80	very-low-density lipoprotein particle clearance	biological process	GO:0034447	3	1	18204	50	APOE
8.218e-03	-4.80	immune complex clearance	biological process	GO:0002434	3	1	18204	50	CLU
8.218e-03	-4.80	mammary placode formation	biological process	GO:0060596	3	1	18204	50	NRG3
8.218e-03	-4.80	bud outgrowth involved in lung branching	biological process	GO:0060447	3	1	18204	50	TNC
8.218e-03	-4.80	response to ionomycin	biological process	GO:1904636	3	1	18204	50	PLCB1
8.218e-03	-4.80	meiotic chromosome movement towards spindle pole	biological process	GO:0016344	3	1	18204	50	FMN2
8.218e-03	-4.80	cellular response to ionomycin	biological process	GO:1904637	3	1	18204	50	PLCB1
8.218e-03	-4.80	trans-synaptic signaling by BDNF, modulating synaptic transmission	biological process	GO:0099183	3	1	18204	50	NTRK2
8.218e-03	-4.80	positive regulation of Schwann cell proliferation	biological process	GO:0010625	3	1	18204	50	GFAP
8.218e-03	-4.80	cysteine transport	biological process	GO:0042883	3	1	18204	50	SLC1A2
8.218e-03	-4.80	radial glia guided migration of Purkinje cell	biological process	GO:0021942	3	1	18204	50	CTNNA2
8.218e-03	-4.80	regulation of SA node cell action potential	biological process	GO:0098907	3	1	18204	50	ANK2
8.218e-03	-4.80	positive regulation of low-density lipoprotein particle receptor catabolic process	biological process	GO:0032805	3	1	18204	50	APOE
8.266e-03	-4.80	central_nervous_system-temporoparietal-glioma-astrocytoma_Grade_IV	COSMIC cancer mutations	central_nervous_system-temporoparietal-glioma-astrocytoma_Grade_IV	48	2	16828	48	RYR3,PARD3
8.327e-03	-4.79	cellular response to nerve growth factor stimulus	biological process	GO:1990090	50	2	18204	50	NTRK2,MAGI2
8.327e-03	-4.79	vasodilation	biological process	GO:0042311	50	2	18204	50	APOE,PRKG1
8.343e-03	-4.79	DSCAM (DS cell adhesion molecule)	protein interactions	1826	162	3	19454	50	CLU,GFAP,MAGI2
8.355e-03	-4.78	positive regulation of macromolecule biosynthetic process	biological process	GO:0010557	2592	14	18204	50	RBMS3,SORBS1,NPAS3,NFIA,APOE,NTRK2,TNC,CLU,ANK2,CNTN1,GLIS3,ERBB4,PLCB1,RORA
8.411e-03	-4.78	upper_aerodigestive_tract-head_neck-carcinoma-squamous_cell_carcinoma	COSMIC cancer mutations	upper_aerodigestive_tract-head_neck-carcinoma-squamous_cell_carcinoma	9263	35	16828	48	ADCY2,PCDH9,SOX5,PTPRZ1,PLCB1,MGAT4C,PRKG1,NTRK2,GLIS3,ERBB4,CNTN1,FMN2,TRPM3,CADM2,NEBL,PITPNC1,SORBS1,GPC5,HPSE2,NKAIN3,CLU,CTNND2,NFIA,TNIK,ANK2,LSAMP,PPP2R2B,TNC,LRP1B,APOE,MAGI2,RORA,RYR3,RGS6,CDH20
8.436e-03	-4.78	protein binding	molecular function	GO:0005515	13983	44	18094	48	CNTN1,TNC,NTM,PPP2R2B,NEBL,LRP1B,CTNND2,CLU,ABLIM1,TNIK,APOE,NPAS3,ERBB4,SLC1A2,FMN2,PTPRZ1,PLCB1,NFIA,PARD3,CTNNA2,PRKG1,CDH20,FUT9,NRG3,NTRK2,HPSE2,SORBS1,CPE,ANK2,RGS6,NRXN1,MAGI2,PITPNC1,ADCY2,DTNA,RYR3,GPM6A,MAPK10,SOX5,LSAMP,RORA,GPC5,GLIS3,GFAP
8.476e-03	-4.77	integrin binding	molecular function	GO:0005178	158	3	18094	48	GFAP,TNC,PTPRZ1
8.547e-03	-4.76	positive regulation of cellular metabolic process	biological process	GO:0031325	3164	16	18204	50	ERBB4,CNTN1,GLIS3,TNIK,MAGI2,PLCB1,RORA,NFIA,RBMS3,NPAS3,SORBS1,CLU,TNC,ANK2,APOE,NTRK2
8.554e-03	-4.76	SNCA (synuclein alpha)	protein interactions	6622	696	6	19454	50	PLCB1,GPM6A,NTRK2,APOE,CLU,TNIK
8.682e-03	-4.75	Retinoid metabolism and transport	REACTOME pathways	R-HSA-975634	44	2	10285	33	GPC5,APOE
8.689e-03	-4.75	Cell-Cell communication	REACTOME pathways	R-HSA-1500931	133	3	10285	33	PARD3,MAGI2,CADM2
8.702e-03	-4.74	learning	biological process	GO:0007612	154	3	18204	50	PLCB1,NRXN1,NTRK2
8.748e-03	-4.74	ZYX (zyxin)	protein interactions	7791	316	4	19454	50	NEBL,ANK2,SORBS1,ABLIM1
8.771e-03	-4.74	positive regulation of nervous system development	biological process	GO:0051962	296	4	18204	50	NRXN1,NTRK2,PTPRZ1,GFAP
8.782e-03	-4.74	FORMIN	prints domains	PR00828	2	1	5227	23	FMN2
8.782e-03	-4.74	CGMPKINASE	prints domains	PR00104	2	1	5227	23	PRKG1
8.814e-03	-4.73	PLCB1 (phospholipase C beta 1)	protein interactions	23236	55	2	19454	50	PARD3,PLCB1
8.841e-03	-4.73	neuronal cell body	cellular component	GO:0043025	489	5	19108	50	APOE,GPM6A,CTNND2,NRXN1,CADM2
8.854e-03	-4.73	terminal O-glycans residues modification	BIOCYC pathways	META_PWY-7434	4	1	902	2	FUT9
8.857e-03	-4.73	regeneration	biological process	GO:0031099	155	3	18204	50	TNC,GFAP,ERBB4
8.873e-03	-4.72	carboxylic acid transport	biological process	GO:0046942	297	4	18204	50	APOE,NTRK2,SLC1A2,GFAP
8.873e-03	-4.72	muscle system process	biological process	GO:0003012	297	4	18204	50	ANK2,DTNA,PRKG1,RYR3
8.976e-03	-4.71	organic acid transport	biological process	GO:0015849	298	4	18204	50	GFAP,APOE,NTRK2,SLC1A2
8.982e-03	-4.71	response to nerve growth factor	biological process	GO:1990089	52	2	18204	50	NTRK2,MAGI2
9.013e-03	-4.71	protein autophosphorylation	biological process	GO:0046777	156	3	18204	50	TNIK,ERBB4,NTRK2
9.013e-03	-4.71	retina development in camera-type eye	biological process	GO:0060041	156	3	18204	50	NFIA,GPM6A,NTRK2
9.068e-03	-4.70	Non-integrin membrane-ECM interactions	REACTOME pathways	R-HSA-3000171	45	2	10285	33	NRXN1,TNC
9.095e-03	-4.70	-	gene3d domains	6.10.250.2510	3	1	14470	44	CTNNA2
9.095e-03	-4.70	-	gene3d domains	2.60.40.2660	3	1	14470	44	ANK2
9.095e-03	-4.70	-	gene3d domains	1.10.490.160	3	1	14470	44	RYR3
9.125e-03	-4.70	SEPTIN3 (septin 3)	protein interactions	55964	56	2	19454	50	GPM6A,PRKG1
9.171e-03	-4.69	positive regulation of endocytosis	biological process	GO:0045807	157	3	18204	50	APOE,MAGI2,CLU
9.171e-03	-4.69	positive regulation of synaptic transmission	biological process	GO:0050806	157	3	18204	50	GFAP,NTRK2,NRXN1
9.272e-03	-4.68	thyroid-carcinoma-medullary_carcinoma	COSMIC cancer mutations	thyroid-carcinoma-medullary_carcinoma	290	4	16828	48	SLC1A2,NRG3,GFAP,PRKG1
9.272e-03	-4.68	medullary_carcinoma	COSMIC cancer mutations	medullary_carcinoma	290	4	16828	48	SLC1A2,NRG3,GFAP,PRKG1
9.303e-03	-4.68	Prot_kinase_dom	interpro domains	IPR000719	480	5	18521	50	ERBB4,TNIK,MAPK10,PRKG1,NTRK2
9.313e-03	-4.68	positive regulation of macromolecule metabolic process	biological process	GO:0010604	3485	17	18204	50	SORBS1,NPAS3,RBMS3,NFIA,NTRK2,APOE,ANK2,TNC,CLU,GLIS3,CNTN1,ERBB4,RORA,PLCB1,MAGI2,FMN2,TNIK
9.318e-03	-4.68	regulation of platelet activation	biological process	GO:0010543	53	2	18204	50	APOE,PRKG1
9.399e-03	-4.67	positive regulation of MAPK cascade	biological process	GO:0043410	473	5	18204	50	ERBB4,TNIK,NTRK2,APOE,PLCB1
9.442e-03	-4.66	NXPH3 (neurexophilin 3)	protein interactions	11248	57	2	19454	50	CTNNA2,NRXN1
9.530e-03	-4.65	human chr3p12.1	chromosome location	human chr3p12.1	5	1	26134	50	CADM2
9.541e-03	-4.65	Ig-like_dom_sf	interpro domains	IPR036179	483	5	18521	50	NTM,NTRK2,CADM2,LSAMP,CNTN1
9.603e-03	-4.65	Rap1 signaling pathway	KEGG pathways	ko04015	210	4	7161	29	MAGI2,ADCY2,PLCB1,PARD3
9.603e-03	-4.65	Rap1 signaling pathway	KEGG pathways	hsa04015	210	4	7161	29	PLCB1,PARD3,MAGI2,ADCY2
9.659e-03	-4.64	positive regulation of receptor-mediated endocytosis	biological process	GO:0048260	54	2	18204	50	CLU,MAGI2
9.659e-03	-4.64	regulation of alcohol biosynthetic process	biological process	GO:1902930	54	2	18204	50	APOE,PRKG1
9.687e-03	-4.64	lipid transfer activity	molecular function	GO:0120013	56	2	18094	48	PITPNC1,APOE
9.763e-03	-4.63	PPP1R12B (protein phosphatase 1 regulatory subunit 12B)	protein interactions	4660	58	2	19454	50	PRKG1,ANK2
9.770e-03	-4.63	regulation of response to stimulus	biological process	GO:0048583	4104	19	18204	50	MAPK10,PLCB1,RORA,GPC5,FMN2,TNIK,MAGI2,RGS6,ERBB4,CTNNA2,NTRK2,APOE,TNC,CLU,SORBS1,RBMS3,CTNND2,NRXN1,PRKG1
9.819e-03	-4.62	negative regulation of supramolecular fiber organization	biological process	GO:1902904	161	3	18204	50	APOE,CLU,CTNNA2
9.833e-03	-4.62	ROR2 (receptor tyrosine kinase like orphan receptor 2)	protein interactions	4920	327	4	19454	50	TNIK,DTNA,PARD3,SORBS1
9.862e-03	-4.62	PLC beta mediated events	REACTOME pathways	R-HSA-112043	47	2	10285	33	PLCB1,ADCY2
9.883e-03	-4.62	testis-germ_cell_tumour-seminoma	COSMIC cancer mutations	testis-germ_cell_tumour-seminoma	648	6	16828	48	TNIK,ANK2,ERBB4,PRKG1,NTRK2,RGS6
1.001e-02	-4.60	intermembrane lipid transfer	biological process	GO:0120009	55	2	18204	50	APOE,PITPNC1
1.009e-02	-4.60	VEGFA (vascular endothelial growth factor A)	protein interactions	7422	59	2	19454	50	PTPRZ1,CLU
1.015e-02	-4.59	receptor-mediated endocytosis	biological process	GO:0006898	163	3	18204	50	APOE,LRP1B,MAGI2
1.017e-02	-4.59	adrenal_gland-adrenal_gland-adrenal_cortical_carcinoma-virilizing_syndrome_producing	COSMIC cancer mutations	adrenal_gland-adrenal_gland-adrenal_cortical_carcinoma-virilizing_syndrome_producing	298	4	16828	48	LRP1B,TNC,FMN2,CTNND2
1.018e-02	-4.59	positive regulation of cellular biosynthetic process	biological process	GO:0031328	2652	14	18204	50	ERBB4,CNTN1,GLIS3,RORA,PLCB1,NFIA,RBMS3,SORBS1,NPAS3,TNC,CLU,ANK2,APOE,NTRK2
1.019e-02	-4.59	macromolecule localization	biological process	GO:0033036	2376	13	18204	50	MAGI2,FMN2,TNIK,CPE,ERBB4,APOE,PITPNC1,CLU,ANK2,PARD3,NRXN1,LRP1B,GFAP
1.024e-02	-4.58	Dnaja1 (DnaJ heat shock protein family (Hsp40) member A1)	protein interactions	15502	4	1	19454	50	GLIS3
1.024e-02	-4.58	Nme2 (NME/NM23 nucleoside diphosphate kinase 2)	protein interactions	18103	4	1	19454	50	RORA
1.024e-02	-4.58	IGKV@ (immunoglobulin kappa variable cluster)	protein interactions	3519	4	1	19454	50	LRP1B
1.024e-02	-4.58	IER5L (immediate early response 5 like)	protein interactions	389792	4	1	19454	50	PPP2R2B
1.024e-02	-4.58	CCDC126 (coiled-coil domain containing 126)	protein interactions	90693	4	1	19454	50	GPM6A
1.027e-02	-4.58	G-protein mediated events	REACTOME pathways	R-HSA-112040	48	2	10285	33	PLCB1,ADCY2
1.029e-02	-4.58	LRP1 (LDL receptor related protein 1)	protein interactions	4035	175	3	19454	50	LRP1B,CLU,APOE
1.032e-02	-4.57	negative regulation of neuron apoptotic process	biological process	GO:0043524	164	3	18204	50	CLU,PTPRZ1,NTRK2
1.036e-02	-4.57	release of sequestered calcium ion into cytosol	biological process	GO:0051209	56	2	18204	50	PLCB1,RYR3
1.042e-02	-4.56	BTN2A1 (butyrophilin subfamily 2 member A1)	protein interactions	11120	60	2	19454	50	PLCB1,FMN2
1.043e-02	-4.56	tenascin complex	cellular component	GO:0090733	4	1	19108	50	TNC
1.043e-02	-4.56	internode region of axon	cellular component	GO:0033269	4	1	19108	50	PARD3
1.043e-02	-4.56	intermediate-density lipoprotein particle	cellular component	GO:0034363	4	1	19108	50	APOE
1.049e-02	-4.56	homophilic cell adhesion via plasma membrane adhesion molecules	biological process	GO:0007156	165	3	18204	50	PCDH9,CDH20,CADM2
1.053e-02	-4.55	side of membrane	cellular component	GO:0098552	715	6	19108	50	LSAMP,GPC5,CNTN1,NTM,DTNA,GFAP
1.057e-02	-4.55	very-low-density lipoprotein particle receptor binding	molecular function	GO:0070326	4	1	18094	48	APOE
1.057e-02	-4.55	ryanodine-sensitive calcium-release channel activity	molecular function	GO:0005219	4	1	18094	48	RYR3
1.057e-02	-4.55	brain-derived neurotrophic factor binding	molecular function	GO:0048403	4	1	18094	48	NTRK2
1.059e-02	-4.55	biliary_tract	COSMIC cancer mutations	biliary_tract	15309	48	16828	48	GFAP,RGS6,RORA,TNC,GPM6A,LRP1B,ANK2,TNIK,LSAMP,DTNA,CTNND2,CLU,NKAIN3,GPC5,CADM2,PITPNC1,ERBB4,TRPM3,FMN2,NTRK2,PRKG1,GLIS3,PTPRZ1,SOX5,NTM,PLCB1,PARD3,ADCY2,NPAS3,CDH20,RYR3,CPE,MAGI2,APOE,PPP2R2B,NFIA,RBMS3,NRXN1,SLC1A2,FUT9,HPSE2,SORBS1,NEBL,CNTN1,ABLIM1,NRG3,MGAT4C,PCDH9
1.062e-02	-4.54	Glutamatergic synapse	KEGG pathways	ko04724	114	3	7161	29	ADCY2,SLC1A2,PLCB1
1.062e-02	-4.54	Glutamatergic synapse	KEGG pathways	hsa04724	114	3	7161	29	PLCB1,SLC1A2,ADCY2
1.067e-02	-4.54	skin-arm-malignant_melanoma	COSMIC cancer mutations	skin-arm-malignant_melanoma	1308	9	16828	48	NTM,RGS6,NPAS3,ANK2,ERBB4,TRPM3,LRP1B,SORBS1,MAGI2
1.072e-02	-4.54	negative regulation of sequestering of calcium ion	biological process	GO:0051283	57	2	18204	50	RYR3,PLCB1
1.075e-02	-4.53	PH_14	pfam domains	PF17787	4	1	17795	48	PLCB1
1.075e-02	-4.53	TRPM_tetra	pfam domains	PF16519	4	1	17795	48	TRPM3
1.075e-02	-4.53	AbLIM_anchor	pfam domains	PF16182	4	1	17795	48	ABLIM1
1.075e-02	-4.53	Glyco_transf_54	pfam domains	PF04666	4	1	17795	48	MGAT4C
1.075e-02	-4.53	Nebulin	pfam domains	PF00880	4	1	17795	48	NEBL
1.075e-02	-4.53	RGS_DHEX	pfam domains	PF18148	4	1	17795	48	RGS6
1.075e-02	-4.53	NKAIN	pfam domains	PF05640	4	1	17795	48	NKAIN3
1.075e-02	-4.53	Apolipoprotein	pfam domains	PF01442	4	1	17795	48	APOE
1.075e-02	-4.53	CTF_NFI	pfam domains	PF00859	4	1	17795	48	NFIA
1.075e-02	-4.53	NfI_DNAbd_pre-N	pfam domains	PF10524	4	1	17795	48	NFIA
1.076e-02	-4.53	PLC-beta_PH	interpro domains	IPR037862	4	1	18521	50	PLCB1
1.076e-02	-4.53	Na/K-Atpase_Interacting	interpro domains	IPR008516	4	1	18521	50	NKAIN3
1.076e-02	-4.53	RGS6/7/9/11_DHEX_sf	interpro domains	IPR047017	4	1	18521	50	RGS6
1.076e-02	-4.53	CTF/NFI_DNA-bd-dom	interpro domains	IPR020604	4	1	18521	50	NFIA
1.076e-02	-4.53	Glyco_transf_54	interpro domains	IPR006759	4	1	18521	50	MGAT4C
1.076e-02	-4.53	PLC-beta	interpro domains	IPR016280	4	1	18521	50	PLCB1
1.076e-02	-4.53	RGS6/7/9/11	interpro domains	IPR047016	4	1	18521	50	RGS6
1.076e-02	-4.53	TRPM_tetra_sf	interpro domains	IPR037162	4	1	18521	50	TRPM3
1.076e-02	-4.53	RGS_DHEX	interpro domains	IPR040759	4	1	18521	50	RGS6
1.076e-02	-4.53	Nebulin_repeat	interpro domains	IPR000900	4	1	18521	50	NEBL
1.076e-02	-4.53	AbLIM_anchor	interpro domains	IPR032402	4	1	18521	50	ABLIM1
1.076e-02	-4.53	CTF/NFI_DNA-bd_CS	interpro domains	IPR019739	4	1	18521	50	NFIA
1.076e-02	-4.53	CTF/NFI	interpro domains	IPR000647	4	1	18521	50	NFIA
1.076e-02	-4.53	PLC-beta_C_sf	interpro domains	IPR042531	4	1	18521	50	PLCB1
1.076e-02	-4.53	TRPM_tetra	interpro domains	IPR032415	4	1	18521	50	TRPM3
1.076e-02	-4.53	Tyr_kinase_EGF/ERB/XmrK_rcpt	interpro domains	IPR016245	4	1	18521	50	ERBB4
1.076e-02	-4.53	CTF/NFI_DNA-bd_N	interpro domains	IPR019548	4	1	18521	50	NFIA
1.076e-02	-4.53	ApoA_E	interpro domains	IPR000074	4	1	18521	50	APOE
1.076e-02	-4.53	PP2A_PR55	interpro domains	IPR000009	4	1	18521	50	PPP2R2B
1.076e-02	-4.53	PP2A_PR55_CS	interpro domains	IPR018067	4	1	18521	50	PPP2R2B
1.076e-02	-4.53	Alpha_catenin	interpro domains	IPR001033	4	1	18521	50	CTNNA2
1.076e-02	-4.53	CP (ceruloplasmin)	protein interactions	1356	61	2	19454	50	PPP2R2B,CLU
1.076e-02	-4.53	PRKG1 (protein kinase cGMP-dependent 1)	protein interactions	5592	61	2	19454	50	PRKG1,TNIK
1.077e-02	-4.53	oligodendroglioma_Grade_III	COSMIC cancer mutations	oligodendroglioma_Grade_III	303	4	16828	48	GLIS3,PTPRZ1,FUT9,MGAT4C
1.079e-02	-4.53	VINCULIN_1	prosite domains	PS00663	3	1	12186	44	CTNNA2
1.079e-02	-4.53	MYELIN_PLP_1	prosite domains	PS00575	3	1	12186	44	GPM6A
1.079e-02	-4.53	SOHO	prosite domains	PS50831	3	1	12186	44	SORBS1
1.079e-02	-4.53	MYELIN_PLP_2	prosite domains	PS01004	3	1	12186	44	GPM6A
1.080e-02	-4.53	extrinsic component of membrane	cellular component	GO:0019898	175	3	19108	50	DTNA,CTNNA2,CDH20
1.084e-02	-4.52	lung-carcinoma-squamous_cell_carcinoma	COSMIC cancer mutations	lung-carcinoma-squamous_cell_carcinoma	14664	47	16828	48	NFIA,NRXN1,SLC1A2,RYR3,CDH20,APOE,MAGI2,CPE,PPP2R2B,NRG3,MGAT4C,PCDH9,FUT9,HPSE2,NEBL,SORBS1,ABLIM1,CNTN1,DTNA,CTNND2,CLU,NKAIN3,RGS6,GFAP,RORA,LRP1B,GPM6A,TNC,LSAMP,TNIK,ANK2,GLIS3,PRKG1,NTRK2,PLCB1,SOX5,NTM,PTPRZ1,PARD3,NPAS3,ADCY2,GPC5,PITPNC1,CADM2,FMN2,TRPM3,ERBB4
1.085e-02	-4.52	adrenal_cortical_adenoma	COSMIC cancer mutations	adrenal_cortical_adenoma	161	3	16828	48	LRP1B,FMN2,ADCY2
1.092e-02	-4.52	regulation of cell communication	biological process	GO:0010646	3541	17	18204	50	ERBB4,RGS6,TNIK,MAGI2,RORA,PLCB1,GPC5,GFAP,RBMS3,CTNND2,NRXN1,SORBS1,CLU,ANK2,NRG3,APOE,NTRK2
1.094e-02	-4.52	germ_cell_tumour	COSMIC cancer mutations	germ_cell_tumour	867	7	16828	48	RGS6,PRKG1,NTRK2,TNIK,ANK2,CNTN1,ERBB4
1.094e-02	-4.52	positive regulation of phospholipid efflux	biological process	GO:1902995	4	1	18204	50	APOE
1.094e-02	-4.52	response to methylmercury	biological process	GO:0051597	4	1	18204	50	ANK2
1.094e-02	-4.52	cardiac muscle tissue regeneration	biological process	GO:0061026	4	1	18204	50	ERBB4
1.094e-02	-4.52	positive regulation of inclusion body assembly	biological process	GO:0090261	4	1	18204	50	CLU
1.094e-02	-4.52	response to caloric restriction	biological process	GO:0061771	4	1	18204	50	APOE
1.094e-02	-4.52	response to fluoride	biological process	GO:1902617	4	1	18204	50	PLCB1
1.094e-02	-4.52	NMDA glutamate receptor clustering	biological process	GO:0097114	4	1	18204	50	APOE
1.094e-02	-4.52	regulation of atrial cardiac muscle cell action potential	biological process	GO:0098910	4	1	18204	50	ANK2
1.094e-02	-4.52	regulation of phospholipid efflux	biological process	GO:1902994	4	1	18204	50	APOE
1.094e-02	-4.52	positive regulation of mesenchymal stem cell differentiation	biological process	GO:2000741	4	1	18204	50	SOX5
1.094e-02	-4.52	protein localization to secretory granule	biological process	GO:0033366	4	1	18204	50	CPE
1.094e-02	-4.52	brain-derived neurotrophic factor receptor signaling pathway	biological process	GO:0031547	4	1	18204	50	NTRK2
1.094e-02	-4.52	N-glycan fucosylation	biological process	GO:0036071	4	1	18204	50	FUT9
1.094e-02	-4.52	trans-synaptic signaling by BDNF	biological process	GO:0099191	4	1	18204	50	NTRK2
1.095e-02	-4.51	tat (Tat)	protein interactions	155871	1718	10	19454	50	GFAP,PRKG1,PPP2R2B,SLC1A2,SORBS1,TNC,PLCB1,ADCY2,RYR3,APOE
1.095e-02	-4.51	import into cell	biological process	GO:0098657	687	6	18204	50	LRP1B,MAGI2,ANK2,GFAP,APOE,SLC1A2
1.120e-02	-4.49	cellular response to growth factor stimulus	biological process	GO:0071363	494	5	18204	50	SOX5,NTRK2,MAGI2,NFIA,ERBB4
1.133e-02	-4.48	actin cytoskeleton	cellular component	GO:0015629	520	5	19108	50	FMN2,NEBL,ABLIM1,SORBS1,CTNNA2
1.143e-02	-4.47	human chr14q13.1	chromosome location	human chr14q13.1	6	1	26134	50	NPAS3
1.143e-02	-4.47	human chr4q34.2	chromosome location	human chr4q34.2	6	1	26134	50	GPM6A
1.144e-02	-4.47	NLGN2 (neuroligin 2)	protein interactions	57555	63	2	19454	50	NRXN1,CLU
1.145e-02	-4.47	protein localization to synapse	biological process	GO:0035418	59	2	18204	50	ERBB4,NRXN1
1.154e-02	-4.46	Signaling by ERBB2	REACTOME pathways	R-HSA-1227986	51	2	10285	33	ERBB4,NRG3
1.161e-02	-4.46	GSN (gelsolin)	protein interactions	2934	183	3	19454	50	DTNA,PPP2R2B,TNIK
1.161e-02	-4.46	MAPK9 (mitogen-activated protein kinase 9)	protein interactions	5601	183	3	19454	50	MAPK10,CLU,GFAP
1.167e-02	-4.45	Sphingolipid signaling pathway	KEGG pathways	hsa04071	118	3	7161	29	PPP2R2B,PLCB1,MAPK10
1.167e-02	-4.45	Sphingolipid signaling pathway	KEGG pathways	ko04071	118	3	7161	29	PPP2R2B,PLCB1,MAPK10
1.176e-02	-4.44	positive regulation of biosynthetic process	biological process	GO:0009891	2697	14	18204	50	NPAS3,SORBS1,RBMS3,NFIA,NTRK2,APOE,ANK2,TNC,CLU,GLIS3,CNTN1,ERBB4,PLCB1,RORA
1.178e-02	-4.44	transmembrane receptor protein tyrosine kinase activity	molecular function	GO:0004714	62	2	18094	48	NTRK2,ERBB4
1.179e-02	-4.44	SYNC (syncoilin, intermediate filament protein)	protein interactions	81493	64	2	19454	50	GFAP,DTNA
1.182e-02	-4.44	regulation of glucose import	biological process	GO:0046324	60	2	18204	50	SLC1A2,SORBS1
1.187e-02	-4.43	lower_third	COSMIC cancer mutations	lower_third	7961	31	16828	48	RYR3,RGS6,CDH20,RORA,CPE,TNC,MAGI2,LRP1B,ANK2,CTNND2,NRXN1,GPC5,HPSE2,CADM2,SORBS1,NEBL,CNTN1,ERBB4,TRPM3,FMN2,NTRK2,PRKG1,NRG3,PTPRZ1,SOX5,MGAT4C,PLCB1,PARD3,PCDH9,ADCY2,NPAS3
1.188e-02	-4.43	arm	COSMIC cancer mutations	arm	1331	9	16828	48	NTM,RGS6,NPAS3,ANK2,ERBB4,TRPM3,LRP1B,SORBS1,MAGI2
1.199e-02	-4.42	Sorb	smart domains	SM00459	3	1	9717	39	SORBS1
1.199e-02	-4.42	PLP	smart domains	SM00002	3	1	9717	39	GPM6A
1.204e-02	-4.42	protein phosphorylation	biological process	GO:0006468	503	5	18204	50	ERBB4,TNIK,PRKG1,NTRK2,MAPK10
1.204e-02	-4.42	central_nervous_system-brain-primitive_neuroectodermal_tumour-medulloblastoma-medullomyoblastoma	COSMIC cancer mutations	central_nervous_system-brain-primitive_neuroectodermal_tumour-medulloblastoma-medullomyoblastoma	485	5	16828	48	CNTN1,LSAMP,PCDH9,RYR3,LRP1B
1.204e-02	-4.42	medullomyoblastoma	COSMIC cancer mutations	medullomyoblastoma	485	5	16828	48	CNTN1,LSAMP,PCDH9,RYR3,LRP1B
1.205e-02	-4.42	primitive_neuroectodermal_tumour-medulloblastoma	COSMIC cancer mutations	primitive_neuroectodermal_tumour-medulloblastoma	15350	48	16828	48	CLU,CTNND2,DTNA,NKAIN3,RORA,GFAP,RGS6,LSAMP,ANK2,TNIK,GPM6A,LRP1B,TNC,PLCB1,PTPRZ1,NTM,SOX5,GLIS3,NTRK2,PRKG1,ADCY2,NPAS3,PARD3,GPC5,TRPM3,FMN2,ERBB4,PITPNC1,CADM2,RBMS3,NFIA,SLC1A2,NRXN1,CDH20,RYR3,PPP2R2B,MAGI2,APOE,CPE,MGAT4C,NRG3,PCDH9,FUT9,HPSE2,CNTN1,ABLIM1,SORBS1,NEBL
1.211e-02	-4.41	Phospholipase C beta, distal C-terminal domain	gene3d domains	1.20.1230.10	4	1	14470	44	PLCB1
1.211e-02	-4.41	TRPM, tetramerisation domain	gene3d domains	1.20.5.1010	4	1	14470	44	TRPM3
1.211e-02	-4.41	-	gene3d domains	1.10.1240.60	4	1	14470	44	RGS6
1.211e-02	-4.41	-	gene3d domains	2.30.29.240	4	1	14470	44	PLCB1
1.215e-02	-4.41	HPX (hemopexin)	protein interactions	3263	65	2	19454	50	CLU,PPP2R2B
1.230e-02	-4.40	muscle cell development	biological process	GO:0055001	175	3	18204	50	PRKG1,ANK2,NEBL
1.230e-02	-4.40	regulation of lipid metabolic process	biological process	GO:0019216	327	4	18204	50	APOE,RORA,SORBS1,PRKG1
1.234e-02	-4.40	establishment of localization	biological process	GO:0051234	3887	18	18204	50	NRXN1,SLC1A2,GPM6A,LRP1B,GFAP,TRPM3,APOE,PITPNC1,NTRK2,CLU,RYR3,PARD3,ANK2,CPE,ERBB4,PLCB1,MAGI2,FMN2
1.242e-02	-4.39	Metabolism of fat-soluble vitamins	REACTOME pathways	R-HSA-6806667	53	2	10285	33	APOE,GPC5
1.248e-02	-4.38	FGB (fibrinogen beta chain)	protein interactions	2244	188	3	19454	50	CLU,PPP2R2B,LRP1B
1.248e-02	-4.38	Vascular smooth muscle contraction	KEGG pathways	hsa04270	121	3	7161	29	PRKG1,ADCY2,PLCB1
1.248e-02	-4.38	Vascular smooth muscle contraction	KEGG pathways	ko04270	121	3	7161	29	PRKG1,ADCY2,PLCB1
1.250e-02	-4.38	MICB (MHC class I polypeptide-related sequence B)	protein interactions	4277	66	2	19454	50	APOE,CLU
1.253e-02	-4.38	SH3_9	pfam domains	PF14604	63	2	17795	48	NEBL,SORBS1
1.261e-02	-4.37	CDH1 (cadherin 1)	protein interactions	999	757	6	19454	50	NEBL,CTNND2,PARD3,ABLIM1,SORBS1,CTNNA2
1.277e-02	-4.36	Neurotransmitter uptake and Metabolism In Glial Cells	REACTOME pathways	R-HSA-112313	4	1	10285	33	SLC1A2
1.277e-02	-4.36	Astrocytic Glutamate-Glutamine Uptake And Metabolism	REACTOME pathways	R-HSA-210455	4	1	10285	33	SLC1A2
1.279e-02	-4.36	TRH (thyrotropin releasing hormone)	protein interactions	7200	5	1	19454	50	CPE
1.279e-02	-4.36	TRPM6 (transient receptor potential cation channel subfamily M member 6)	protein interactions	140803	5	1	19454	50	TRPM3
1.279e-02	-4.36	NRG2 (neuregulin 2)	protein interactions	9542	5	1	19454	50	ERBB4
1.279e-02	-4.36	Wwp2 (WW domain containing E3 ubiquitin protein ligase 2)	protein interactions	66894	5	1	19454	50	GLIS3
1.279e-02	-4.36	RVS161 (amphiphysin-like protein RVS161)	protein interactions	850367	5	1	19454	50	GFAP
1.279e-02	-4.36	ADCYAP1R1 (ADCYAP receptor type I)	protein interactions	117	5	1	19454	50	CLU
1.279e-02	-4.36	PPP1R17 (protein phosphatase 1 regulatory subunit 17)	protein interactions	10842	5	1	19454	50	PRKG1
1.279e-02	-4.36	EPPIN (epididymal peptidase inhibitor)	protein interactions	57119	5	1	19454	50	CLU
1.279e-02	-4.36	SYT13 (synaptotagmin 13)	protein interactions	57586	5	1	19454	50	NRXN1
1.279e-02	-4.36	SLC10A3 (solute carrier family 10 member 3)	protein interactions	8273	5	1	19454	50	SORBS1
1.282e-02	-4.36	regulation of small molecule metabolic process	biological process	GO:0062012	331	4	18204	50	RORA,APOE,SORBS1,PRKG1
1.287e-02	-4.35	ARMC1 (armadillo repeat containing 1)	protein interactions	55156	67	2	19454	50	GPM6A,CNTN1
1.287e-02	-4.35	SHC3 (SHC adaptor protein 3)	protein interactions	53358	67	2	19454	50	ERBB4,NTRK2
1.287e-02	-4.35	PARD6A (par-6 family cell polarity regulator alpha)	protein interactions	50855	67	2	19454	50	PARD3,PLCB1
1.287e-02	-4.35	Heparan sulfate/heparin (HS-GAG) metabolism	REACTOME pathways	R-HSA-1638091	54	2	10285	33	HPSE2,GPC5
1.298e-02	-4.34	regulation of nitric oxide biosynthetic process	biological process	GO:0045428	63	2	18204	50	APOE,CLU
1.302e-02	-4.34	neurofibrillary tangle	cellular component	GO:0097418	5	1	19108	50	CLU
1.305e-02	-4.34	Platelet activation	KEGG pathways	hsa04611	123	3	7161	29	PLCB1,ADCY2,PRKG1
1.308e-02	-4.34	virilizing_syndrome_producing	COSMIC cancer mutations	virilizing_syndrome_producing	321	4	16828	48	CTNND2,FMN2,TNC,LRP1B
1.310e-02	-4.34	central_nervous_system-cerebrum-glioma-astrocytoma_Grade_IV	COSMIC cancer mutations	central_nervous_system-cerebrum-glioma-astrocytoma_Grade_IV	61	2	16828	48	LRP1B,CNTN1
1.310e-02	-4.34	temporoparietal	COSMIC cancer mutations	temporoparietal	61	2	16828	48	PARD3,RYR3
1.313e-02	-4.33	Kinase-like_dom_sf	interpro domains	IPR011009	523	5	18521	50	ERBB4,TNIK,NTRK2,PRKG1,MAPK10
1.315e-02	-4.33	MYELINPLP	prints domains	PR00214	3	1	5227	23	GPM6A
1.315e-02	-4.33	NTKRECEPTOR	prints domains	PR01939	3	1	5227	23	NTRK2
1.315e-02	-4.33	RYANODINER	prints domains	PR00795	3	1	5227	23	RYR3
1.315e-02	-4.33	JNKMAPKINASE	prints domains	PR01772	3	1	5227	23	MAPK10
1.315e-02	-4.33	RORNUCRECPTR	prints domains	PR01293	3	1	5227	23	RORA
1.320e-02	-4.33	neurotrophin receptor activity	molecular function	GO:0005030	5	1	18094	48	NTRK2
1.320e-02	-4.33	neuroligin family protein binding	molecular function	GO:0097109	5	1	18094	48	NRXN1
1.320e-02	-4.33	high-affinity L-glutamate transmembrane transporter activity	molecular function	GO:0005314	5	1	18094	48	SLC1A2
1.320e-02	-4.33	glutamate:sodium symporter activity	molecular function	GO:0015501	5	1	18094	48	SLC1A2
1.320e-02	-4.33	syndecan binding	molecular function	GO:0045545	5	1	18094	48	TNC
1.323e-02	-4.33	CXADR (CXADR Ig-like cell adhesion molecule)	protein interactions	1525	357	4	19454	50	TNIK,NEBL,PARD3,SORBS1
1.324e-02	-4.32	PLCH1 (phospholipase C eta 1)	protein interactions	23007	68	2	19454	50	NTRK2,PARD3
1.332e-02	-4.32	human chr13q21.32	chromosome location	human chr13q21.32	7	1	26134	50	PCDH9
1.332e-02	-4.32	human chr4q21.3	chromosome location	human chr4q21.3	7	1	26134	50	MAPK10
1.337e-02	-4.31	transport	biological process	GO:0006810	3615	17	18204	50	APOE,TRPM3,NTRK2,PITPNC1,RYR3,CLU,ANK2,NRXN1,GPM6A,SLC1A2,LRP1B,GFAP,PLCB1,FMN2,MAGI2,CPE,ERBB4
1.337e-02	-4.31	actin filament bundle assembly	biological process	GO:0051017	64	2	18204	50	SORBS1,FMN2
1.337e-02	-4.31	dendrite morphogenesis	biological process	GO:0048813	64	2	18204	50	CTNND2,CTNNA2
1.342e-02	-4.31	Vinculin	pfam domains	PF01044	5	1	17795	48	CTNNA2
1.342e-02	-4.31	IP_trans	pfam domains	PF02121	5	1	17795	48	PITPNC1
1.342e-02	-4.31	EGF_Tenascin	pfam domains	PF18720	5	1	17795	48	TNC
1.342e-02	-4.31	Protocadherin	pfam domains	PF08374	5	1	17795	48	PCDH9
1.343e-02	-4.31	Vinculin/catenin	interpro domains	IPR006077	5	1	18521	50	CTNNA2
1.343e-02	-4.31	PI_transfer	interpro domains	IPR001666	5	1	18521	50	PITPNC1
1.343e-02	-4.31	Protocadherin	interpro domains	IPR013585	5	1	18521	50	PCDH9
1.343e-02	-4.31	EGF_Tenascin	interpro domains	IPR041161	5	1	18521	50	TNC
1.346e-02	-4.31	cell-cell junction organization	biological process	GO:0045216	181	3	18204	50	CDH20,ANK2,PARD3
1.359e-02	-4.30	skin-head_neck-carcinoma-squamous_cell_carcinoma	COSMIC cancer mutations	skin-head_neck-carcinoma-squamous_cell_carcinoma	14191	46	16828	48	GLIS3,PRKG1,NTRK2,PLCB1,NTM,SOX5,PTPRZ1,PARD3,NPAS3,ADCY2,GPC5,PITPNC1,CADM2,FMN2,TRPM3,ERBB4,DTNA,CTNND2,CLU,NKAIN3,RGS6,GFAP,RORA,LRP1B,GPM6A,TNC,LSAMP,TNIK,ANK2,NRG3,MGAT4C,PCDH9,HPSE2,FUT9,NEBL,SORBS1,ABLIM1,CNTN1,NFIA,NRXN1,SLC1A2,CDH20,RYR3,MAGI2,CPE,PPP2R2B
1.366e-02	-4.29	AMPA glutamate receptor clustering	biological process	GO:0097113	5	1	18204	50	APOE
1.366e-02	-4.29	central nervous system myelin maintenance	biological process	GO:0032286	5	1	18204	50	CLU
1.366e-02	-4.29	cellular response to prostaglandin D stimulus	biological process	GO:0071799	5	1	18204	50	TNC
1.366e-02	-4.29	ERBB2-ERBB4 signaling pathway	biological process	GO:0038135	5	1	18204	50	ERBB4
1.366e-02	-4.29	response to prostaglandin D	biological process	GO:0071798	5	1	18204	50	TNC
1.366e-02	-4.29	positive regulation of dendritic spine maintenance	biological process	GO:1902952	5	1	18204	50	APOE
1.366e-02	-4.29	chylomicron remnant clearance	biological process	GO:0034382	5	1	18204	50	APOE
1.366e-02	-4.29	membrane depolarization during SA node cell action potential	biological process	GO:0086046	5	1	18204	50	ANK2
1.366e-02	-4.29	activation of meiosis	biological process	GO:0090427	5	1	18204	50	PLCB1
1.366e-02	-4.29	polar body extrusion after meiotic divisions	biological process	GO:0040038	5	1	18204	50	FMN2
1.366e-02	-4.29	negative regulation of glutamate secretion	biological process	GO:0014050	5	1	18204	50	PRKG1
1.366e-02	-4.29	synaptic signaling via neuropeptide	biological process	GO:0099538	5	1	18204	50	NTRK2
1.366e-02	-4.29	gephyrin clustering involved in postsynaptic density assembly	biological process	GO:0097116	5	1	18204	50	NRXN1
1.366e-02	-4.29	glutamate receptor clustering	biological process	GO:0097688	5	1	18204	50	APOE
1.369e-02	-4.29	EGF	pfam domains	PF00008	66	2	17795	48	NRXN1,LRP1B
1.369e-02	-4.29	main axon	cellular component	GO:0044304	68	2	19108	50	PARD3,SLC1A2
1.377e-02	-4.29	apoptotic mitochondrial changes	biological process	GO:0008637	65	2	18204	50	CLU,ERBB4
1.377e-02	-4.29	regulation of nitric oxide metabolic process	biological process	GO:0080164	65	2	18204	50	APOE,CLU
1.377e-02	-4.29	long-term synaptic potentiation	biological process	GO:0060291	65	2	18204	50	NTRK2,GFAP
1.377e-02	-4.29	positive regulation of synapse assembly	biological process	GO:0051965	65	2	18204	50	NRXN1,NTRK2
1.386e-02	-4.28	regulation of carbohydrate metabolic process	biological process	GO:0006109	183	3	18204	50	RORA,SORBS1,PRKG1
1.388e-02	-4.28	oesophagus-lower_third-carcinoma-squamous_cell_carcinoma	COSMIC cancer mutations	oesophagus-lower_third-carcinoma-squamous_cell_carcinoma	3507	17	16828	48	FMN2,TRPM3,CNTN1,ERBB4,LRP1B,MAGI2,HPSE2,GPC5,RYR3,NPAS3,ADCY2,PCDH9,PARD3,PLCB1,CTNND2,PTPRZ1,PRKG1
1.389e-02	-4.28	regulation of Wnt signaling pathway	biological process	GO:0030111	339	4	18204	50	RBMS3,GPC5,APOE,CTNND2
1.393e-02	-4.27	stomach-adenocarcinoma	COSMIC cancer mutations	stomach-adenocarcinoma	4101	19	16828	48	SLC1A2,PCDH9,PARD3,CTNND2,PLCB1,MGAT4C,NRG3,ABLIM1,ERBB4,CNTN1,ANK2,FMN2,PPP2R2B,TNC,NEBL,LRP1B,GPC5,RORA,CDH20
1.399e-02	-4.27	PCDH20 (protocadherin 20)	protein interactions	64881	70	2	19454	50	MGAT4C,CTNNA2
1.399e-02	-4.27	MTMR9 (myotubularin related protein 9)	protein interactions	66036	70	2	19454	50	CLU,ERBB4
1.399e-02	-4.27	PTPDC1 (protein tyrosine phosphatase domain containing 1)	protein interactions	138639	70	2	19454	50	PPP2R2B,ERBB4
1.399e-02	-4.27	DUSP10 (dual specificity phosphatase 10)	protein interactions	11221	70	2	19454	50	MAPK10,ERBB4
1.408e-02	-4.26	cell population proliferation	biological process	GO:0008283	726	6	18204	50	RORA,SOX5,NFIA,CLU,HPSE2,GFAP
1.414e-02	-4.26	PIK3R3 (phosphoinositide-3-kinase regulatory subunit 3)	protein interactions	8503	197	3	19454	50	NTRK2,NEBL,ERBB4
1.418e-02	-4.26	ERBB signaling pathway	biological process	GO:0038127	66	2	18204	50	ERBB4,NRG3
1.418e-02	-4.26	cardiac muscle cell development	biological process	GO:0055013	66	2	18204	50	NEBL,PRKG1
1.437e-02	-4.24	PR55_2	prosite domains	PS01025	4	1	12186	44	PPP2R2B
1.437e-02	-4.24	NEBULIN	prosite domains	PS51216	4	1	12186	44	NEBL
1.437e-02	-4.24	CTF_NFI_2	prosite domains	PS51080	4	1	12186	44	NFIA
1.437e-02	-4.24	CTF_NFI_1	prosite domains	PS00349	4	1	12186	44	NFIA
1.437e-02	-4.24	PR55_1	prosite domains	PS01024	4	1	12186	44	PPP2R2B
1.437e-02	-4.24	ANK2 (ankyrin 2)	protein interactions	287	71	2	19454	50	GPM6A,TNIK
1.455e-02	-4.23	Activation of PKC Through G Protein-Coupled Receptor	SMPDB pathways	SMP0000749	4	1	1369	5	PLCB1
1.459e-02	-4.23	cholesterol transport	biological process	GO:0030301	67	2	18204	50	CLU,APOE
1.470e-02	-4.22	central_nervous_system-medulla-primitive_neuroectodermal_tumour-medulloblastoma-classic	COSMIC cancer mutations	central_nervous_system-medulla-primitive_neuroectodermal_tumour-medulloblastoma-classic	14773	47	16828	48	PPP2R2B,APOE,MAGI2,CPE,RYR3,CDH20,SLC1A2,NRXN1,RBMS3,NFIA,ABLIM1,CNTN1,NEBL,SORBS1,HPSE2,FUT9,PCDH9,MGAT4C,NRG3,LSAMP,TNIK,ANK2,LRP1B,GPM6A,TNC,RORA,RGS6,GFAP,CLU,CTNND2,DTNA,FMN2,TRPM3,ERBB4,PITPNC1,CADM2,GPC5,NPAS3,ADCY2,PARD3,PLCB1,NTM,SOX5,PTPRZ1,GLIS3,PRKG1,NTRK2
1.470e-02	-4.22	central_nervous_system-medulla-primitive_neuroectodermal_tumour-medulloblastoma	COSMIC cancer mutations	central_nervous_system-medulla-primitive_neuroectodermal_tumour-medulloblastoma	14773	47	16828	48	TNC,LRP1B,GPM6A,TNIK,ANK2,LSAMP,RGS6,GFAP,RORA,DTNA,CTNND2,CLU,CADM2,PITPNC1,ERBB4,FMN2,TRPM3,GPC5,PARD3,NPAS3,ADCY2,PRKG1,NTRK2,GLIS3,SOX5,NTM,PTPRZ1,PLCB1,CPE,APOE,MAGI2,PPP2R2B,CDH20,RYR3,NRXN1,SLC1A2,NFIA,RBMS3,NEBL,SORBS1,ABLIM1,CNTN1,FUT9,HPSE2,PCDH9,NRG3,MGAT4C
1.470e-02	-4.22	central_nervous_system-medulla-primitive_neuroectodermal_tumour-medulloblastoma-large_cell	COSMIC cancer mutations	central_nervous_system-medulla-primitive_neuroectodermal_tumour-medulloblastoma-large_cell	14773	47	16828	48	PARD3,ADCY2,NPAS3,NTRK2,PRKG1,GLIS3,PTPRZ1,SOX5,NTM,PLCB1,CADM2,PITPNC1,ERBB4,TRPM3,FMN2,GPC5,DTNA,CTNND2,CLU,TNC,GPM6A,LRP1B,ANK2,TNIK,LSAMP,GFAP,RGS6,RORA,PCDH9,NRG3,MGAT4C,SORBS1,NEBL,CNTN1,ABLIM1,FUT9,HPSE2,NRXN1,SLC1A2,NFIA,RBMS3,CPE,APOE,MAGI2,PPP2R2B,CDH20,RYR3
1.470e-02	-4.22	central_nervous_system-medulla-primitive_neuroectodermal_tumour-medulloblastoma-desmoplastic	COSMIC cancer mutations	central_nervous_system-medulla-primitive_neuroectodermal_tumour-medulloblastoma-desmoplastic	14773	47	16828	48	PPP2R2B,CPE,APOE,MAGI2,RYR3,CDH20,SLC1A2,NRXN1,RBMS3,NFIA,ABLIM1,CNTN1,NEBL,SORBS1,FUT9,HPSE2,PCDH9,MGAT4C,NRG3,TNIK,ANK2,LSAMP,TNC,LRP1B,GPM6A,RORA,RGS6,GFAP,CLU,CTNND2,DTNA,ERBB4,FMN2,TRPM3,CADM2,PITPNC1,GPC5,NPAS3,ADCY2,PARD3,NTM,SOX5,PTPRZ1,PLCB1,PRKG1,NTRK2,GLIS3
1.474e-02	-4.22	classic	COSMIC cancer mutations	classic	14774	47	16828	48	RYR3,CDH20,CPE,APOE,MAGI2,PPP2R2B,NFIA,RBMS3,NRXN1,SLC1A2,HPSE2,FUT9,SORBS1,NEBL,CNTN1,ABLIM1,NRG3,MGAT4C,PCDH9,GFAP,RGS6,RORA,TNC,GPM6A,LRP1B,ANK2,TNIK,LSAMP,DTNA,CLU,CTNND2,GPC5,CADM2,PITPNC1,ERBB4,TRPM3,FMN2,NTRK2,PRKG1,GLIS3,PTPRZ1,SOX5,NTM,PLCB1,PARD3,ADCY2,NPAS3
1.476e-02	-4.22	Ppp1cb (protein phosphatase 1 catalytic subunit beta)	protein interactions	19046	72	2	19454	50	PARD3,ABLIM1
1.476e-02	-4.22	DPYSL3 (dihydropyrimidinase like 3)	protein interactions	1809	72	2	19454	50	GPM6A,TNIK
1.485e-02	-4.21	central_nervous_system-brainstem-primitive_neuroectodermal_tumour-medulloblastoma-WNT_subtype	COSMIC cancer mutations	central_nervous_system-brainstem-primitive_neuroectodermal_tumour-medulloblastoma-WNT_subtype	181	3	16828	48	MAGI2,PPP2R2B,NPAS3
1.490e-02	-4.21	LIM	pfam domains	PF00412	69	2	17795	48	ABLIM1,NEBL
1.490e-02	-4.21	medulla	COSMIC cancer mutations	medulla	14778	47	16828	48	CTNND2,CLU,DTNA,RORA,GFAP,RGS6,ANK2,TNIK,LSAMP,TNC,GPM6A,LRP1B,PTPRZ1,NTM,SOX5,PLCB1,NTRK2,PRKG1,GLIS3,ADCY2,NPAS3,PARD3,GPC5,ERBB4,TRPM3,FMN2,CADM2,PITPNC1,RBMS3,NFIA,SLC1A2,NRXN1,RYR3,CDH20,PPP2R2B,CPE,APOE,MAGI2,MGAT4C,NRG3,PCDH9,FUT9,HPSE2,CNTN1,ABLIM1,SORBS1,NEBL
1.492e-02	-4.21	TIAM1 (TIAM Rac1 associated GEF 1)	protein interactions	7074	201	3	19454	50	RYR3,PARD3,DTNA
1.495e-02	-4.20	desmoplastic	COSMIC cancer mutations	desmoplastic	14779	47	16828	48	RBMS3,NFIA,SLC1A2,NRXN1,CDH20,RYR3,PPP2R2B,CPE,MAGI2,APOE,MGAT4C,NRG3,PCDH9,HPSE2,FUT9,ABLIM1,CNTN1,NEBL,SORBS1,CTNND2,CLU,DTNA,RORA,RGS6,GFAP,TNIK,ANK2,LSAMP,TNC,LRP1B,GPM6A,NTM,SOX5,PTPRZ1,PLCB1,PRKG1,NTRK2,GLIS3,NPAS3,ADCY2,PARD3,GPC5,ERBB4,FMN2,TRPM3,CADM2,PITPNC1
1.501e-02	-4.20	actin filament bundle organization	biological process	GO:0061572	68	2	18204	50	FMN2,SORBS1
1.507e-02	-4.20	WNT_subtype	COSMIC cancer mutations	WNT_subtype	182	3	16828	48	PPP2R2B,NPAS3,MAGI2
1.510e-02	-4.19	regulation of lipid biosynthetic process	biological process	GO:0046890	189	3	18204	50	APOE,SORBS1,PRKG1
1.511e-02	-4.19	Apolipoprotein	gene3d domains	1.20.120.20	5	1	14470	44	APOE
1.514e-02	-4.19	Dopaminergic synapse	KEGG pathways	hsa04728	130	3	7161	29	PLCB1,MAPK10,PPP2R2B
1.514e-02	-4.19	Dopaminergic synapse	KEGG pathways	ko04728	130	3	7161	29	PPP2R2B,PLCB1,MAPK10
1.515e-02	-4.19	PCDHGB1 (protocadherin gamma subfamily B, 1)	protein interactions	56104	73	2	19454	50	CNTN1,PCDH9
1.531e-02	-4.18	ig	pfam domains	PF00047	70	2	17795	48	CNTN1,NTM
1.532e-02	-4.18	ADCY1 (adenylate cyclase 1)	protein interactions	107	6	1	19454	50	ADCY2
1.532e-02	-4.18	NRG4 (neuregulin 4)	protein interactions	145957	6	1	19454	50	ERBB4
1.532e-02	-4.18	Itch (itchy, E3 ubiquitin protein ligase)	protein interactions	16396	6	1	19454	50	GLIS3
1.532e-02	-4.18	TPPP3 (tubulin polymerization promoting protein family member 3)	protein interactions	51673	6	1	19454	50	PPP2R2B
1.532e-02	-4.18	SMOC2 (SPARC related modular calcium binding 2)	protein interactions	64094	6	1	19454	50	TNC
1.532e-02	-4.18	SOX1 (SRY-box transcription factor 1)	protein interactions	6656	6	1	19454	50	SOX5
1.532e-02	-4.18	Rara (retinoic acid receptor, alpha)	protein interactions	19401	6	1	19454	50	MAPK10
1.532e-02	-4.18	SYTL3 (synaptotagmin like 3)	protein interactions	94120	6	1	19454	50	NRXN1
1.532e-02	-4.18	DRP2 (dystrophin related protein 2)	protein interactions	1821	6	1	19454	50	DTNA
1.532e-02	-4.18	SOX11 (SRY-box transcription factor 11)	protein interactions	6664	6	1	19454	50	SOX5
1.532e-02	-4.18	LBX2 (ladybird homeobox 2)	protein interactions	85474	6	1	19454	50	GFAP
1.532e-02	-4.18	FXYD7 (FXYD domain containing ion transport regulator 7)	protein interactions	53822	6	1	19454	50	APOE
1.532e-02	-4.18	Tiam2 (T cell lymphoma invasion and metastasis 2)	protein interactions	24001	6	1	19454	50	DTNA
1.532e-02	-4.18	SLC12A5 (solute carrier family 12 member 5)	protein interactions	57468	6	1	19454	50	GPM6A
1.532e-02	-4.18	LCAT (lecithin-cholesterol acyltransferase)	protein interactions	3931	6	1	19454	50	APOE
1.532e-02	-4.18	Zbtb2 (zinc finger and BTB domain containing 2)	protein interactions	381990	6	1	19454	50	SORBS1
1.532e-02	-4.18	Taok2 (TAO kinase 2)	protein interactions	381921	6	1	19454	50	CLU
1.532e-02	-4.18	CYRIA (CYFIP related Rac1 interactor A)	protein interactions	81553	6	1	19454	50	GPM6A
1.535e-02	-4.18	Immunoglobulin	interpro domains	IPR013151	70	2	18521	50	NTM,CNTN1
1.541e-02	-4.17	GJA1 (gap junction protein alpha 1)	protein interactions	2697	572	5	19454	50	ERBB4,PARD3,DTNA,PCDH9,TNIK
1.543e-02	-4.17	regulation of blood coagulation	biological process	GO:0030193	69	2	18204	50	APOE,PRKG1
1.551e-02	-4.17	pancreas-carcinoma-adenocarcinoma	COSMIC cancer mutations	pancreas-carcinoma-adenocarcinoma	517	5	16828	48	TNC,NEBL,LRP1B,GPC5,HPSE2
1.552e-02	-4.17	CASK (calcium/calmodulin dependent serine protein kinase)	protein interactions	8573	204	3	19454	50	NRXN1,DTNA,ABLIM1
1.560e-02	-4.16	PAR polarity complex	cellular component	GO:0120157	6	1	19108	50	PARD3
1.560e-02	-4.16	multivesicular body, internal vesicle	cellular component	GO:0097487	6	1	19108	50	APOE
1.566e-02	-4.16	haematopoietic_and_lymphoid_tissue-soft_tissue-lymphoid_neoplasm-diffuse_large_B_cell_lymphoma	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue-soft_tissue-lymphoid_neoplasm-diffuse_large_B_cell_lymphoma	67	2	16828	48	PCDH9,LRP1B
1.566e-02	-4.16	cerebrum	COSMIC cancer mutations	cerebrum	67	2	16828	48	LRP1B,CNTN1
1.576e-02	-4.15	Znf_LIM	interpro domains	IPR001781	71	2	18521	50	NEBL,ABLIM1
1.581e-02	-4.15	calcium-induced calcium release activity	molecular function	GO:0048763	6	1	18094	48	RYR3
1.581e-02	-4.15	4-galactosyl-N-acetylglucosaminide 3-alpha-L-fucosyltransferase activity	molecular function	GO:0017083	6	1	18094	48	FUT9
1.581e-02	-4.15	phosphatidylcholine-sterol O-acyltransferase activator activity	molecular function	GO:0060228	6	1	18094	48	APOE
1.584e-02	-4.15	liver-carcinoma-hepatocellular_carcinoma	COSMIC cancer mutations	liver-carcinoma-hepatocellular_carcinoma	14800	47	16828	48	MGAT4C,NRG3,PCDH9,FUT9,HPSE2,CNTN1,ABLIM1,SORBS1,NEBL,NFIA,SLC1A2,NRXN1,CDH20,RYR3,PPP2R2B,MAGI2,APOE,CPE,PLCB1,PTPRZ1,NTM,SOX5,GLIS3,NTRK2,PRKG1,ADCY2,NPAS3,PARD3,GPC5,TRPM3,FMN2,ERBB4,PITPNC1,CADM2,CLU,CTNND2,DTNA,NKAIN3,RORA,GFAP,RGS6,LSAMP,ANK2,TNIK,GPM6A,LRP1B,TNC
1.584e-02	-4.15	hepatocellular_carcinoma	COSMIC cancer mutations	hepatocellular_carcinoma	14800	47	16828	48	CTNND2,CLU,NFIA,DTNA,SLC1A2,NRXN1,NKAIN3,RORA,CDH20,RGS6,RYR3,GFAP,LSAMP,PPP2R2B,TNIK,ANK2,LRP1B,MAGI2,GPM6A,APOE,CPE,TNC,PLCB1,MGAT4C,SOX5,NTM,PTPRZ1,GLIS3,NRG3,PRKG1,NTRK2,NPAS3,ADCY2,PCDH9,PARD3,FUT9,HPSE2,GPC5,FMN2,TRPM3,ABLIM1,CNTN1,ERBB4,NEBL,PITPNC1,SORBS1,CADM2
1.585e-02	-4.14	negative regulation of smooth muscle cell proliferation	biological process	GO:0048662	70	2	18204	50	APOE,PRKG1
1.592e-02	-4.14	cellular process	biological process	GO:0009987	14996	47	18204	50	HPSE2,PITPNC1,APOE,NFIA,LRP1B,CTNND2,TNIK,GPC5,PLCB1,CDH20,CNTN1,NRG3,PARD3,RYR3,TNC,ADCY2,SLC1A2,GPM6A,NRXN1,NTM,DTNA,ERBB4,GLIS3,PTPRZ1,CLU,NEBL,LSAMP,TRPM3,GFAP,FUT9,ABLIM1,CADM2,CTNNA2,SOX5,CPE,RGS6,PCDH9,ANK2,NTRK2,PRKG1,MGAT4C,SORBS1,FMN2,MAGI2,PPP2R2B,MAPK10,RORA
1.592e-02	-4.14	breast-carcinoma-basal_(triple-negative)_carcinoma	COSMIC cancer mutations	breast-carcinoma-basal_(triple-negative)_carcinoma	2981	15	16828	48	NPAS3,ADCY2,PARD3,NTM,NRG3,PRKG1,NTRK2,FMN2,TRPM3,PPP2R2B,CNTN1,ERBB4,LRP1B,NEBL,MAGI2
1.592e-02	-4.14	basal_(triple-negative)_carcinoma	COSMIC cancer mutations	basal_(triple-negative)_carcinoma	2981	15	16828	48	FMN2,PPP2R2B,TRPM3,CNTN1,ERBB4,NEBL,LRP1B,MAGI2,NPAS3,ADCY2,PARD3,NTM,NRG3,PRKG1,NTRK2
1.594e-02	-4.14	HDAC9 (histone deacetylase 9)	protein interactions	9734	75	2	19454	50	GFAP,MAPK10
1.594e-02	-4.14	NGF-independant TRKA activation	REACTOME pathways	R-HSA-187024	5	1	10285	33	NTRK2
1.596e-02	-4.14	NEBU	smart domains	SM00227	4	1	9717	39	NEBL
1.598e-02	-4.14	Transferase(Phosphotransferase) domain 1	gene3d domains	1.10.510.10	490	5	14470	44	NTRK2,ERBB4,TNIK,PRKG1,MAPK10
1.608e-02	-4.13	cell-cell contact zone	cellular component	GO:0044291	74	2	19108	50	PCDH9,ANK2
1.608e-02	-4.13	Ins145_P3_rec	pfam domains	PF08709	6	1	17795	48	RYR3
1.608e-02	-4.13	EF-hand_3	pfam domains	PF09069	6	1	17795	48	DTNA
1.608e-02	-4.13	RYDR_ITPR	pfam domains	PF01365	6	1	17795	48	RYR3
1.608e-02	-4.13	Glypican	pfam domains	PF01153	6	1	17795	48	GPC5
1.608e-02	-4.13	Syndecan	pfam domains	PF01034	6	1	17795	48	NRXN1
1.608e-02	-4.13	EF-hand_2	pfam domains	PF09068	6	1	17795	48	DTNA
1.608e-02	-4.13	GF_recep_IV	pfam domains	PF14843	6	1	17795	48	ERBB4
1.608e-02	-4.13	Adcy_cons_dom	pfam domains	PF06327	6	1	17795	48	ADCY2
1.608e-02	-4.13	RIH_assoc	pfam domains	PF08454	6	1	17795	48	RYR3
1.609e-02	-4.13	GLI-like	interpro domains	IPR043359	6	1	18521	50	GLIS3
1.609e-02	-4.13	Ryanodine_IP3_receptor	interpro domains	IPR015925	6	1	18521	50	RYR3
1.609e-02	-4.13	GF_recep_IV	interpro domains	IPR032778	6	1	18521	50	ERBB4
1.609e-02	-4.13	Ins145_P3_rcpt	interpro domains	IPR014821	6	1	18521	50	RYR3
1.609e-02	-4.13	RyR/IP3R_RIH_dom_sf	interpro domains	IPR035910	6	1	18521	50	RYR3
1.609e-02	-4.13	EF-hand_dom_typ1	interpro domains	IPR015153	6	1	18521	50	DTNA
1.609e-02	-4.13	RIH_assoc-dom	interpro domains	IPR013662	6	1	18521	50	RYR3
1.609e-02	-4.13	Syndecan/Neurexin_dom	interpro domains	IPR027789	6	1	18521	50	NRXN1
1.609e-02	-4.13	Glypican_CS	interpro domains	IPR019803	6	1	18521	50	GPC5
1.609e-02	-4.13	Adcy_conserved_dom	interpro domains	IPR009398	6	1	18521	50	ADCY2
1.609e-02	-4.13	RIH_dom	interpro domains	IPR000699	6	1	18521	50	RYR3
1.609e-02	-4.13	Glypican	interpro domains	IPR001863	6	1	18521	50	GPC5
1.609e-02	-4.13	EF-hand_dom_typ2	interpro domains	IPR015154	6	1	18521	50	DTNA
1.615e-02	-4.13	organelle organization	biological process	GO:0006996	3091	15	18204	50	FMN2,TNIK,ERBB4,CTNNA2,NEBL,APOE,PARD3,ANK2,CLU,SORBS1,NRXN1,GFAP,PRKG1,ABLIM1,NFIA
1.624e-02	-4.12	Ca2+ pathway	REACTOME pathways	R-HSA-4086398	61	2	10285	33	PLCB1,PRKG1
1.624e-02	-4.12	Cell-cell junction organization	REACTOME pathways	R-HSA-421270	61	2	10285	33	PARD3,CADM2
1.627e-02	-4.12	protein-containing complex binding	molecular function	GO:0044877	1772	10	18094	48	NEBL,CLU,ABLIM1,PTPRZ1,ANK2,APOE,TNC,GFAP,NFIA,CTNNA2
1.628e-02	-4.12	regulation of hemostasis	biological process	GO:1900046	71	2	18204	50	APOE,PRKG1
1.629e-02	-4.12	MKRN2 (makorin ring finger protein 2)	protein interactions	23609	380	4	19454	50	PRKG1,CNTN1,PARD3,MAGI2
1.633e-02	-4.11	BCL2L1 (BCL2 like 1)	protein interactions	598	208	3	19454	50	CLU,RYR3,ABLIM1
1.637e-02	-4.11	regulation of low-density lipoprotein particle receptor catabolic process	biological process	GO:0032803	6	1	18204	50	APOE
1.637e-02	-4.11	relaxation of vascular associated smooth muscle	biological process	GO:0060087	6	1	18204	50	PRKG1
1.637e-02	-4.11	postsynaptic density protein 95 clustering	biological process	GO:0097119	6	1	18204	50	NRXN1
1.637e-02	-4.11	L-aspartate import across plasma membrane	biological process	GO:0140009	6	1	18204	50	SLC1A2
1.637e-02	-4.11	inositol trisphosphate metabolic process	biological process	GO:0032957	6	1	18204	50	PLCB1
1.637e-02	-4.11	vocal learning	biological process	GO:0042297	6	1	18204	50	NRXN1
1.637e-02	-4.11	mammary gland formation	biological process	GO:0060592	6	1	18204	50	NRG3
1.637e-02	-4.11	establishment of meiotic spindle localization	biological process	GO:0051295	6	1	18204	50	FMN2
1.637e-02	-4.11	T-tubule organization	biological process	GO:0033292	6	1	18204	50	ANK2
1.637e-02	-4.11	imitative learning	biological process	GO:0098596	6	1	18204	50	NRXN1
1.637e-02	-4.11	protein targeting to vacuole involved in autophagy	biological process	GO:0071211	6	1	18204	50	CLU
1.637e-02	-4.11	asymmetric neuroblast division	biological process	GO:0055059	6	1	18204	50	SOX5
1.637e-02	-4.11	planar cell polarity pathway involved in axis elongation	biological process	GO:0003402	6	1	18204	50	MAGI2
1.637e-02	-4.11	triglyceride-rich lipoprotein particle clearance	biological process	GO:0071830	6	1	18204	50	APOE
1.637e-02	-4.11	paranodal junction assembly	biological process	GO:0030913	6	1	18204	50	ANK2
1.637e-02	-4.11	cellular response to ether	biological process	GO:0071362	6	1	18204	50	PLCB1
1.665e-02	-4.10	positive regulation of gene expression	biological process	GO:0010628	1212	8	18204	50	CNTN1,RORA,RBMS3,PLCB1,NTRK2,CLU,TNC,ANK2
1.672e-02	-4.09	protein N-linked glycosylation	biological process	GO:0006487	72	2	18204	50	MGAT4C,FUT9
1.676e-02	-4.09	ADGRL2 (adhesion G protein-coupled receptor L2)	protein interactions	23266	77	2	19454	50	PARD3,NTRK2
1.676e-02	-4.09	actin cytoskeleton organization	biological process	GO:0030036	547	5	18204	50	SORBS1,NEBL,PRKG1,TNIK,FMN2
1.711e-02	-4.07	regulation of protein catabolic process	biological process	GO:0042176	361	4	18204	50	GFAP,CLU,FMN2,APOE
1.715e-02	-4.07	Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour	COSMIC cancer mutations	Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour	7434	29	16828	48	NRXN1,NKAIN3,DTNA,CTNND2,TNC,LRP1B,TNIK,ANK2,PPP2R2B,RGS6,RYR3,RORA,PARD3,NPAS3,ADCY2,PRKG1,NTRK2,GLIS3,NRG3,SOX5,PTPRZ1,CADM2,NEBL,SORBS1,ABLIM1,CNTN1,ERBB4,FMN2,TRPM3
1.716e-02	-4.07	negative regulation of wound healing	biological process	GO:0061045	73	2	18204	50	PRKG1,APOE
1.716e-02	-4.07	peptide metabolic process	biological process	GO:0006518	73	2	18204	50	CPE,SLC1A2
1.716e-02	-4.07	cardiac cell development	biological process	GO:0055006	73	2	18204	50	NEBL,PRKG1
1.717e-02	-4.06	LRP8 (LDL receptor related protein 8)	protein interactions	7804	78	2	19454	50	CLU,APOE
1.731e-02	-4.06	positive regulation of ERK1 and ERK2 cascade	biological process	GO:0070374	199	3	18204	50	ERBB4,NTRK2,APOE
1.731e-02	-4.06	testis	COSMIC cancer mutations	testis	733	6	16828	48	ANK2,ERBB4,TNIK,RGS6,NTRK2,PRKG1
1.743e-02	-4.05	FN3_sf	interpro domains	IPR036116	203	3	18521	50	TNC,CNTN1,PTPRZ1
1.743e-02	-4.05	FN3_dom	interpro domains	IPR003961	203	3	18521	50	PTPRZ1,TNC,CNTN1
1.749e-02	-4.05	PP2APR55	prints domains	PR00600	4	1	5227	23	PPP2R2B
1.749e-02	-4.05	ALPHACATENIN	prints domains	PR00805	4	1	5227	23	CTNNA2
1.759e-02	-4.04	KRTAP3-2 (keratin associated protein 3-2)	protein interactions	83897	79	2	19454	50	NTM,GFAP
1.759e-02	-4.04	STMN2 (stathmin 2)	protein interactions	11075	79	2	19454	50	MAPK10,RGS6
1.761e-02	-4.04	NCK1 (NCK adaptor protein 1)	protein interactions	4690	214	3	19454	50	TNIK,NTRK2,ERBB4
1.761e-02	-4.04	positive regulation of gliogenesis	biological process	GO:0014015	74	2	18204	50	GFAP,PTPRZ1
1.761e-02	-4.04	regulation of coagulation	biological process	GO:0050818	74	2	18204	50	PRKG1,APOE
1.761e-02	-4.04	sterol transport	biological process	GO:0015918	74	2	18204	50	CLU,APOE
1.767e-02	-4.04	mannosyl-glycoprotein N-acetylglucosaminyltransferases	BIOCYC pathways	META_PWY-7426	8	1	902	2	MGAT4C
1.767e-02	-4.04	terminal O-glycans residues modification	BIOCYC pathways	HUMAN_PWY-7434	8	1	902	2	FUT9
1.775e-02	-4.03	Apelin signaling pathway	KEGG pathways	hsa04371	138	3	7161	29	ADCY2,RYR3,PLCB1
1.776e-02	-4.03	GABA-ergic synapse	cellular component	GO:0098982	78	2	19108	50	PLCB1,ERBB4
1.780e-02	-4.03	structural molecule activity	molecular function	GO:0005198	793	6	18094	48	TNC,NEBL,GFAP,ANK2,CTNNA2,APOE
1.786e-02	-4.03	C7 (complement C7)	protein interactions	730	7	1	19454	50	CLU
1.786e-02	-4.03	SLC16A5 (solute carrier family 16 member 5)	protein interactions	9121	7	1	19454	50	PTPRZ1
1.786e-02	-4.03	SOAT2 (sterol O-acyltransferase 2)	protein interactions	8435	7	1	19454	50	CLU
1.786e-02	-4.03	CYP4F8 (cytochrome P450 family 4 subfamily F member 8)	protein interactions	11283	7	1	19454	50	CLU
1.786e-02	-4.03	CHL1 (cell adhesion molecule L1 like)	protein interactions	10752	7	1	19454	50	ANK2
1.786e-02	-4.03	ABCC12 (ATP binding cassette subfamily C member 12)	protein interactions	94160	7	1	19454	50	NPAS3
1.786e-02	-4.03	C8B (complement C8 beta chain)	protein interactions	732	7	1	19454	50	CLU
1.786e-02	-4.03	DSCAML1 (DS cell adhesion molecule like 1)	protein interactions	57453	7	1	19454	50	MAGI2
1.786e-02	-4.03	Smurf1 (SMAD specific E3 ubiquitin protein ligase 1)	protein interactions	75788	7	1	19454	50	GLIS3
1.793e-02	-4.02	large_cell	COSMIC cancer mutations	large_cell	14845	47	16828	48	CPE,MAGI2,APOE,PPP2R2B,RYR3,CDH20,NRXN1,SLC1A2,NFIA,RBMS3,NEBL,SORBS1,ABLIM1,CNTN1,HPSE2,FUT9,PCDH9,NRG3,MGAT4C,TNC,LRP1B,GPM6A,TNIK,ANK2,LSAMP,RGS6,GFAP,RORA,DTNA,CTNND2,CLU,CADM2,PITPNC1,ERBB4,FMN2,TRPM3,GPC5,PARD3,NPAS3,ADCY2,PRKG1,NTRK2,GLIS3,SOX5,NTM,PTPRZ1,PLCB1
1.794e-02	-4.02	adrenal_gland-adrenal_gland-adrenal_cortical_adenoma-cortisol_producing	COSMIC cancer mutations	adrenal_gland-adrenal_gland-adrenal_cortical_adenoma-cortisol_producing	72	2	16828	48	LRP1B,FMN2
1.794e-02	-4.02	cortisol_producing	COSMIC cancer mutations	cortisol_producing	72	2	16828	48	LRP1B,FMN2
1.795e-02	-4.02	protein kinase activity	molecular function	GO:0004672	577	5	18094	48	NTRK2,MAPK10,PRKG1,ERBB4,TNIK
1.800e-02	-4.02	intracellular calcium ion homeostasis	biological process	GO:0006874	202	3	18204	50	ANK2,RYR3,APOE
1.801e-02	-4.02	MAP2 (microtubule associated protein 2)	protein interactions	4133	80	2	19454	50	GPM6A,APOE
1.801e-02	-4.02	CEACAM21 (CEA cell adhesion molecule 21)	protein interactions	90273	80	2	19454	50	PCDH9,CNTN1
1.811e-02	-4.01	IP3 receptor type 1 binding core, RIH domain	gene3d domains	1.25.10.30	6	1	14470	44	RYR3
1.811e-02	-4.01	Single helix bin	gene3d domains	1.20.5.490	6	1	14470	44	PRKG1
1.815e-02	-4.01	Corticotropin Activation of Cortisol Production	SMPDB pathways	SMP0000310	5	1	1369	5	ADCY2
1.831e-02	-4.00	Constitutive Signaling by Aberrant PI3K in Cancer	REACTOME pathways	R-HSA-2219530	65	2	10285	33	ERBB4,NRG3
1.840e-02	-4.00	actin filament binding	molecular function	GO:0051015	211	3	18094	48	ABLIM1,NEBL,CTNNA2
1.843e-02	-3.99	phosphatidic acid transfer activity	molecular function	GO:1990050	7	1	18094	48	PITPNC1
1.843e-02	-3.99	mitogen-activated protein kinase p38 binding	molecular function	GO:0048273	7	1	18094	48	PRKG1
1.850e-02	-3.99	PRKCA (protein kinase C alpha)	protein interactions	5578	395	4	19454	50	PRKG1,GFAP,GPM6A,PLCB1
1.865e-02	-3.98	Protein_kinase_ATP_BS	interpro domains	IPR017441	377	4	18521	50	ERBB4,PRKG1,NTRK2,TNIK
1.873e-02	-3.98	IG_LIKE	prosite domains	PS50835	430	5	12186	44	LSAMP,NTM,CADM2,NTRK2,CNTN1
1.873e-02	-3.98	SDF	pfam domains	PF00375	7	1	17795	48	SLC1A2
1.873e-02	-3.98	Recep_L_domain	pfam domains	PF01030	7	1	17795	48	ERBB4
1.873e-02	-3.98	Filament_head	pfam domains	PF04732	7	1	17795	48	GFAP
1.873e-02	-3.98	Furin-like	pfam domains	PF00757	7	1	17795	48	ERBB4
1.875e-02	-3.98	Furin-like_Cys-rich_dom	interpro domains	IPR006211	7	1	18521	50	ERBB4
1.875e-02	-3.98	Na-dicarboxylate_symporter	interpro domains	IPR001991	7	1	18521	50	SLC1A2
1.875e-02	-3.98	Na:dicarbo_symporter_sf	interpro domains	IPR036458	7	1	18521	50	SLC1A2
1.875e-02	-3.98	Rcpt_L-dom_sf	interpro domains	IPR036941	7	1	18521	50	ERBB4
1.875e-02	-3.98	Rcpt_L-dom	interpro domains	IPR000494	7	1	18521	50	ERBB4
1.875e-02	-3.98	Plakophilin/d_Catenin	interpro domains	IPR028435	7	1	18521	50	CTNND2
1.875e-02	-3.98	Hud_Sxl_RNA	interpro domains	IPR002343	7	1	18521	50	RBMS3
1.875e-02	-3.98	Alpha-catenin/vinculin-like_sf	interpro domains	IPR036723	7	1	18521	50	CTNNA2
1.875e-02	-3.98	Na-dicarboxylate_symporter_CS	interpro domains	IPR018107	7	1	18521	50	SLC1A2
1.875e-02	-3.98	Intermed_filament_DNA-bd	interpro domains	IPR006821	7	1	18521	50	GFAP
1.886e-02	-3.97	GSC (goosecoid homeobox)	protein interactions	145258	82	2	19454	50	NFIA,SOX5
1.897e-02	-3.96	human chr9p24.2	chromosome location	human chr9p24.2	10	1	26134	50	GLIS3
1.898e-02	-3.96	neural retina development	biological process	GO:0003407	77	2	18204	50	GPM6A,NTRK2
1.898e-02	-3.96	cellular response to interleukin-1	biological process	GO:0071347	77	2	18204	50	RORA,PLCB1
1.905e-02	-3.96	kidney-Wilms_tumour	COSMIC cancer mutations	kidney-Wilms_tumour	545	5	16828	48	TNIK,ERBB4,FMN2,PRKG1,NTRK2
1.907e-02	-3.96	regulation of oligodendrocyte progenitor proliferation	biological process	GO:0070445	7	1	18204	50	PTPRZ1
1.907e-02	-3.96	high-density lipoprotein particle clearance	biological process	GO:0034384	7	1	18204	50	APOE
1.907e-02	-3.96	peripheral nervous system axon regeneration	biological process	GO:0014012	7	1	18204	50	TNC
1.907e-02	-3.96	very-low-density lipoprotein particle remodeling	biological process	GO:0034372	7	1	18204	50	APOE
1.907e-02	-3.96	SA node cell action potential	biological process	GO:0086015	7	1	18204	50	ANK2
1.907e-02	-3.96	positive regulation of receptor catabolic process	biological process	GO:2000646	7	1	18204	50	APOE
1.907e-02	-3.96	glial cell fate specification	biological process	GO:0021780	7	1	18204	50	NFIA
1.907e-02	-3.96	chromosome movement towards spindle pole	biological process	GO:0051305	7	1	18204	50	FMN2
1.907e-02	-3.96	relaxation of smooth muscle	biological process	GO:0044557	7	1	18204	50	PRKG1
1.907e-02	-3.96	SA node cell to atrial cardiac muscle cell signaling	biological process	GO:0086018	7	1	18204	50	ANK2
1.907e-02	-3.96	parallel actin filament bundle assembly	biological process	GO:0030046	7	1	18204	50	FMN2
1.907e-02	-3.96	negative regulation of Arp2/3 complex-mediated actin nucleation	biological process	GO:0034316	7	1	18204	50	CTNNA2
1.907e-02	-3.96	observational learning	biological process	GO:0098597	7	1	18204	50	NRXN1
1.907e-02	-3.96	interneuron migration from the subpallium to the cortex	biological process	GO:0021830	7	1	18204	50	NRG3
1.907e-02	-3.96	cellular response to magnesium ion	biological process	GO:0071286	7	1	18204	50	RYR3
1.907e-02	-3.96	regulation of monocyte extravasation	biological process	GO:2000437	7	1	18204	50	PLCB1
1.907e-02	-3.96	chaperone-mediated autophagy	biological process	GO:0061684	7	1	18204	50	CLU
1.907e-02	-3.96	regulation of testosterone biosynthetic process	biological process	GO:2000224	7	1	18204	50	PRKG1
1.910e-02	-3.96	Activation of TRKA receptors	REACTOME pathways	R-HSA-187015	6	1	10285	33	NTRK2
1.919e-02	-3.95	Wilms_tumour	COSMIC cancer mutations	Wilms_tumour	546	5	16828	48	PRKG1,NTRK2,FMN2,TNIK,ERBB4
1.925e-02	-3.95	RHOB (ras homolog family member B)	protein interactions	388	832	6	19454	50	PARD3,DTNA,PLCB1,FMN2,ABLIM1,TNIK
1.930e-02	-3.95	SYT1 (synaptotagmin 1)	protein interactions	6857	83	2	19454	50	GPM6A,NRXN1
1.937e-02	-3.94	sarcomere	cellular component	GO:0030017	218	3	19108	50	ANK2,NEBL,RYR3
1.938e-02	-3.94	Signaling by PTK6	REACTOME pathways	R-HSA-8848021	67	2	10285	33	ERBB4,NRG3
1.944e-02	-3.94	regulation of glucose transmembrane transport	biological process	GO:0010827	78	2	18204	50	SORBS1,SLC1A2
1.954e-02	-3.94	transmembrane receptor protein kinase activity	molecular function	GO:0019199	81	2	18094	48	NTRK2,ERBB4
1.960e-02	-3.93	skin-leg-malignant_melanoma	COSMIC cancer mutations	skin-leg-malignant_melanoma	549	5	16828	48	LRP1B,NEBL,NRG3,PTPRZ1,PLCB1
1.966e-02	-3.93	eye-uveal_tract-malignant_melanoma-spindle	COSMIC cancer mutations	eye-uveal_tract-malignant_melanoma-spindle	363	4	16828	48	CPE,PCDH9,CTNND2,TRPM3
1.974e-02	-3.93	PSEN2 (presenilin 2)	protein interactions	5664	84	2	19454	50	CTNND2,GFAP
1.974e-02	-3.93	Tyr_kinase_cat_dom	interpro domains	IPR020635	80	2	18521	50	ERBB4,NTRK2
1.976e-02	-3.92	FBXO2 (F-box protein 2)	protein interactions	26232	403	4	19454	50	CNTN1,LRP1B,PCDH9,NTM
1.979e-02	-3.92	IG	smart domains	SM00409	394	5	9717	39	NTRK2,NTM,LSAMP,CADM2,CNTN1
1.980e-02	-3.92	regulation of system process	biological process	GO:0044057	571	5	18204	50	PARD3,ANK2,PRKG1,NRXN1,APOE
1.980e-02	-3.92	heart development	biological process	GO:0007507	571	5	18204	50	ANK2,ERBB4,PRKG1,NEBL,CPE
1.984e-02	-3.92	DDX39A (DExD-box helicase 39A)	protein interactions	10212	1081	7	19454	50	GFAP,PTPRZ1,RYR3,GLIS3,NPAS3,SORBS1,CADM2
1.986e-02	-3.92	Adrenergic signaling in cardiomyocytes	KEGG pathways	ko04261	144	3	7161	29	PPP2R2B,PLCB1,ADCY2
1.986e-02	-3.92	Adrenergic signaling in cardiomyocytes	KEGG pathways	hsa04261	144	3	7161	29	PLCB1,ADCY2,PPP2R2B
1.990e-02	-3.92	Regulation of lipolysis in adipocytes	KEGG pathways	hsa04923	54	2	7161	29	PRKG1,ADCY2
2.015e-02	-3.90	skin-upper_arm-malignant_melanoma	COSMIC cancer mutations	skin-upper_arm-malignant_melanoma	553	5	16828	48	ERBB4,FUT9,FMN2,PLCB1,LRP1B
2.022e-02	-3.90	nitrogen compound transport	biological process	GO:0071705	1507	9	18204	50	APOE,NTRK2,CLU,FMN2,ANK2,CPE,SLC1A2,LRP1B,GFAP
2.038e-02	-3.89	CCK (cholecystokinin)	protein interactions	885	8	1	19454	50	CPE
2.038e-02	-3.89	Chmp2a (charged multivesicular body protein 2A)	protein interactions	68953	8	1	19454	50	CLU
2.038e-02	-3.89	UBALD2 (UBA like domain containing 2)	protein interactions	283991	8	1	19454	50	GFAP
2.038e-02	-3.89	NKAIN3 (sodium/potassium transporting ATPase interacting 3)	protein interactions	286183	8	1	19454	50	GFAP
2.038e-02	-3.89	INSM1 (INSM transcriptional repressor 1)	protein interactions	3642	8	1	19454	50	SORBS1
2.063e-02	-3.88	SYNJ1 (synaptojanin 1)	protein interactions	8867	86	2	19454	50	SORBS1,GPM6A
2.063e-02	-3.88	FAM171A1 (family with sequence similarity 171 member A1)	protein interactions	221061	86	2	19454	50	PARD3,NTRK2
2.067e-02	-3.88	lobular_carcinoma	COSMIC cancer mutations	lobular_carcinoma	763	6	16828	48	TNIK,ERBB4,PRKG1,NTRK2,CDH20,LRP1B
2.067e-02	-3.88	breast-carcinoma-lobular_carcinoma	COSMIC cancer mutations	breast-carcinoma-lobular_carcinoma	763	6	16828	48	ERBB4,TNIK,CDH20,LRP1B,NTRK2,PRKG1
2.072e-02	-3.88	Cysteine Rich Protein	gene3d domains	2.10.110.10	73	2	14470	44	NEBL,ABLIM1
2.075e-02	-3.88	spherical high-density lipoprotein particle	cellular component	GO:0034366	8	1	19108	50	CLU
2.075e-02	-3.88	zonula adherens	cellular component	GO:0005915	8	1	19108	50	SORBS1
2.092e-02	-3.87	phosphatidylinositol-4,5-bisphosphate binding	molecular function	GO:0005546	84	2	18094	48	PLCB1,PARD3
2.094e-02	-3.87	positive regulation of transmembrane transport	biological process	GO:0034764	214	3	18204	50	SLC1A2,SORBS1,ANK2
2.103e-02	-3.86	VANGL1 (VANGL planar cell polarity protein 1)	protein interactions	81839	229	3	19454	50	ERBB4,PARD3,NTRK2
2.103e-02	-3.86	alpha-(1->3)-fucosyltransferase activity	molecular function	GO:0046920	8	1	18094	48	FUT9
2.103e-02	-3.86	cyclic nucleotide-dependent protein kinase activity	molecular function	GO:0004690	8	1	18094	48	PRKG1
2.103e-02	-3.86	phosphorylation-dependent protein binding	molecular function	GO:0140031	8	1	18094	48	ANK2
2.108e-02	-3.86	ZNF608 (zinc finger protein 608)	protein interactions	57507	87	2	19454	50	SOX5,NFIA
2.108e-02	-3.86	TGFA (transforming growth factor alpha)	protein interactions	7039	87	2	19454	50	ERBB4,MAGI2
2.110e-02	-3.86	Sodium:dicarboxylate symporter	gene3d domains	1.10.3860.10	7	1	14470	44	SLC1A2
2.110e-02	-3.86	Receptor L-domain	gene3d domains	3.80.20.20	7	1	14470	44	ERBB4
2.127e-02	-3.85	DST (dystonin)	protein interactions	667	230	3	19454	50	TNIK,NTRK2,PARD3
2.127e-02	-3.85	positive regulation of metabolic process	biological process	GO:0009893	3796	17	18204	50	PLCB1,RORA,MAGI2,FMN2,TNIK,CNTN1,GLIS3,ERBB4,APOE,NTRK2,TNC,CLU,ANK2,RBMS3,NPAS3,SORBS1,NFIA
2.130e-02	-3.85	salivary_gland-parotid-carcinoma-adenoid_cystic_carcinoma	COSMIC cancer mutations	salivary_gland-parotid-carcinoma-adenoid_cystic_carcinoma	561	5	16828	48	ERBB4,TNIK,LRP1B,RYR3,NTRK2
2.135e-02	-3.85	regulation of steroid biosynthetic process	biological process	GO:0050810	82	2	18204	50	PRKG1,APOE
2.138e-02	-3.85	AC_N	pfam domains	PF16214	8	1	17795	48	ADCY2
2.138e-02	-3.85	Glyco_tran_10_N	pfam domains	PF17039	8	1	17795	48	FUT9
2.138e-02	-3.85	Glyco_transf_10	pfam domains	PF00852	8	1	17795	48	FUT9
2.138e-02	-3.85	LSDAT_euk	pfam domains	PF18139	8	1	17795	48	TRPM3
2.138e-02	-3.85	VHP	pfam domains	PF02209	8	1	17795	48	ABLIM1
2.140e-02	-3.84	Glyco_tran_10_N	interpro domains	IPR031481	8	1	18521	50	FUT9
2.140e-02	-3.84	TRPM_SLOG	interpro domains	IPR041491	8	1	18521	50	TRPM3
2.140e-02	-3.84	Villin_headpiece_dom_sf	interpro domains	IPR036886	8	1	18521	50	ABLIM1
2.140e-02	-3.84	AC_N	interpro domains	IPR032628	8	1	18521	50	ADCY2
2.140e-02	-3.84	Adcy	interpro domains	IPR030672	8	1	18521	50	ADCY2
2.140e-02	-3.84	Villin_headpiece	interpro domains	IPR003128	8	1	18521	50	ABLIM1
2.140e-02	-3.84	Glyco_trans_10	interpro domains	IPR001503	8	1	18521	50	FUT9
2.140e-02	-3.84	GT10-like_C_sf	interpro domains	IPR038577	8	1	18521	50	FUT9
2.147e-02	-3.84	GLYPICAN	prosite domains	PS01207	6	1	12186	44	GPC5
2.153e-02	-3.84	FGA (fibrinogen alpha chain)	protein interactions	2243	88	2	19454	50	PPP2R2B,LRP1B
2.159e-02	-3.84	FN3	smart domains	SM00060	149	3	9717	39	PTPRZ1,CNTN1,TNC
2.175e-02	-3.83	Dopamine Activation of Neurological Reward System	SMPDB pathways	SMP0000308	6	1	1369	5	ADCY2
2.175e-02	-3.83	Phospholipase C Signaling Pathway	SMPDB pathways	SMP0063783	6	1	1369	5	PLCB1
2.175e-02	-3.83	Intracellular Signalling Through PGD2 receptor and Prostaglandin D2	SMPDB pathways	SMP0000343	6	1	1369	5	ADCY2
2.177e-02	-3.83	ion channel modulating, G protein-coupled receptor signaling pathway	biological process	GO:0099105	8	1	18204	50	PLCB1
2.177e-02	-3.83	triglyceride-rich lipoprotein particle remodeling	biological process	GO:0034370	8	1	18204	50	APOE
2.177e-02	-3.83	regulation of synapse structural plasticity	biological process	GO:0051823	8	1	18204	50	CTNNA2
2.177e-02	-3.83	regulation of chaperone-mediated autophagy	biological process	GO:1904714	8	1	18204	50	GFAP
2.177e-02	-3.83	regulation of Cdc42 protein signal transduction	biological process	GO:0032489	8	1	18204	50	APOE
2.177e-02	-3.83	cell proliferation in external granule layer	biological process	GO:0021924	8	1	18204	50	RORA
2.177e-02	-3.83	meiotic cytokinesis	biological process	GO:0033206	8	1	18204	50	FMN2
2.177e-02	-3.83	phospholipase C-activating G protein-coupled acetylcholine receptor signaling pathway	biological process	GO:0007207	8	1	18204	50	PLCB1
2.177e-02	-3.83	insulin processing	biological process	GO:0030070	8	1	18204	50	CPE
2.177e-02	-3.83	positive regulation of amyloid-beta clearance	biological process	GO:1900223	8	1	18204	50	APOE
2.177e-02	-3.83	response to vasopressin	biological process	GO:1904116	8	1	18204	50	PLCB1
2.177e-02	-3.83	cerebellar granule cell precursor proliferation	biological process	GO:0021930	8	1	18204	50	RORA
2.177e-02	-3.83	central nervous system myelin formation	biological process	GO:0032289	8	1	18204	50	CNTN1
2.177e-02	-3.83	cell proliferation in hindbrain	biological process	GO:0021534	8	1	18204	50	RORA
2.177e-02	-3.83	positive regulation of CoA-transferase activity	biological process	GO:1905920	8	1	18204	50	APOE
2.177e-02	-3.83	cellular response to vasopressin	biological process	GO:1904117	8	1	18204	50	PLCB1
2.182e-02	-3.83	PITRANSFER	prints domains	PR00391	5	1	5227	23	PITPNC1
2.194e-02	-3.82	regulation of cell population proliferation	biological process	GO:0042127	1790	10	18204	50	PRKG1,ERBB4,GFAP,PTPRZ1,MAGI2,TNC,CLU,HPSE2,APOE,NTRK2
2.196e-02	-3.82	skin-leg-malignant_melanoma-superficial_spreading	COSMIC cancer mutations	skin-leg-malignant_melanoma-superficial_spreading	210	3	16828	48	NTM,PRKG1,LRP1B
2.224e-02	-3.81	regulation of synaptic plasticity	biological process	GO:0048167	219	3	18204	50	GFAP,APOE,NTRK2
2.224e-02	-3.81	HMG20A (high mobility group 20A)	protein interactions	10363	234	3	19454	50	SOX5,NFIA,DTNA
2.225e-02	-3.81	Neurofascin interactions	REACTOME pathways	R-HSA-447043	7	1	10285	33	CNTN1
2.233e-02	-3.80	regulation of sodium ion transport	biological process	GO:0002028	84	2	18204	50	NKAIN3,CNTN1
2.233e-02	-3.80	peripheral nervous system development	biological process	GO:0007422	84	2	18204	50	NTRK2,PARD3
2.240e-02	-3.80	ErbB Signaling Pathway	WikiPathways	WP673	54	2	5310	23	NRG3,ERBB4
2.246e-02	-3.80	SEMG1 (semenogelin 1)	protein interactions	6406	90	2	19454	50	CLU,PPP2R2B
2.246e-02	-3.80	CTDSPL (CTD small phosphatase like)	protein interactions	10217	90	2	19454	50	DTNA,FMN2
2.249e-02	-3.79	large_intestine-rectum	COSMIC cancer mutations	large_intestine-rectum	569	5	16828	48	PRKG1,CNTN1,ERBB4,ADCY2,FMN2
2.260e-02	-3.79	synovial	COSMIC cancer mutations	synovial	8	1	16828	48	CNTN1
2.260e-02	-3.79	bone-knee-chondrosarcoma-synovial	COSMIC cancer mutations	bone-knee-chondrosarcoma-synovial	8	1	16828	48	CNTN1
2.272e-02	-3.78	human chr3p24.1	chromosome location	human chr3p24.1	12	1	26134	50	RBMS3
2.278e-02	-3.78	atypical_teratoid-rhabdoid_tumour	COSMIC cancer mutations	atypical_teratoid-rhabdoid_tumour	213	3	16828	48	FMN2,MAGI2,PCDH9
2.278e-02	-3.78	central_nervous_system-brain-atypical_teratoid-rhabdoid_tumour	COSMIC cancer mutations	central_nervous_system-brain-atypical_teratoid-rhabdoid_tumour	213	3	16828	48	PCDH9,MAGI2,FMN2
2.288e-02	-3.78	Oxytocin signaling pathway	KEGG pathways	ko04921	152	3	7161	29	ADCY2,PLCB1,RYR3
2.288e-02	-3.78	Oxytocin signaling pathway	KEGG pathways	hsa04921	152	3	7161	29	ADCY2,PLCB1,RYR3
2.290e-02	-3.78	IER5 (immediate early response 5)	protein interactions	51278	9	1	19454	50	PPP2R2B
2.290e-02	-3.78	LINC02582 (long intergenic non-protein coding RNA 2582)	protein interactions	100505817	9	1	19454	50	APOE
2.290e-02	-3.78	CACNA2D3 (calcium voltage-gated channel auxiliary subunit alpha2delta 3)	protein interactions	55799	9	1	19454	50	APOE
2.290e-02	-3.78	MUC4 (mucin 4, cell surface associated)	protein interactions	4585	9	1	19454	50	ERBB4
2.290e-02	-3.78	LSB3 (Lsb3p)	protein interactions	850580	9	1	19454	50	GFAP
2.290e-02	-3.78	Tyw3 (tRNA-yW synthesizing protein 3 homolog (S. cerevisiae))	protein interactions	209584	9	1	19454	50	CTNNA2
2.290e-02	-3.78	PI3 (peptidase inhibitor 3)	protein interactions	5266	9	1	19454	50	PPP2R2B
2.292e-02	-3.78	PTPN21 (protein tyrosine phosphatase non-receptor type 21)	protein interactions	11099	91	2	19454	50	ERBB4,NRG3
2.292e-02	-3.78	SOS1 (SOS Ras/Rac guanine nucleotide exchange factor 1)	protein interactions	6654	91	2	19454	50	SORBS1,TNIK
2.299e-02	-3.77	CAMK2A (calcium/calmodulin dependent protein kinase II alpha)	protein interactions	815	237	3	19454	50	SOX5,GFAP,GPM6A
2.324e-02	-3.76	LCOR (ligand dependent nuclear receptor corepressor)	protein interactions	84458	238	3	19454	50	LRP1B,CLU,MAGI2
2.331e-02	-3.76	amyloid-beta binding	molecular function	GO:0001540	89	2	18094	48	APOE,CLU
2.331e-02	-3.76	astrocyte end-foot	cellular component	GO:0097450	9	1	19108	50	GFAP
2.331e-02	-3.76	flotillin complex	cellular component	GO:0016600	9	1	19108	50	SORBS1
2.331e-02	-3.76	slit diaphragm	cellular component	GO:0036057	9	1	19108	50	MAGI2
2.331e-02	-3.76	filtration diaphragm	cellular component	GO:0036056	9	1	19108	50	MAGI2
2.334e-02	-3.76	protein localization to cell junction	biological process	GO:1902414	86	2	18204	50	NRXN1,ERBB4
2.339e-02	-3.76	RLN1 (relaxin 1)	protein interactions	6013	92	2	19454	50	LRP1B,CPE
2.346e-02	-3.75	cellular response to oxygen-containing compound	biological process	GO:1901701	1047	7	18204	50	PLCB1,RORA,ADCY2,TNC,RYR3,SLC1A2,SORBS1
2.352e-02	-3.75	organic anion transport	biological process	GO:0015711	398	4	18204	50	APOE,SLC1A2,NTRK2,GFAP
2.367e-02	-3.74	regulation of signaling	biological process	GO:0023051	3534	16	18204	50	ERBB4,RGS6,MAGI2,TNIK,RORA,PLCB1,GPC5,GFAP,SORBS1,NRXN1,RBMS3,CTNND2,NRG3,CLU,NTRK2,APOE
2.367e-02	-3.74	Hippo signaling pathway	KEGG pathways	hsa04390	154	3	7161	29	CTNNA2,PPP2R2B,PARD3
2.367e-02	-3.74	Hippo signaling pathway	KEGG pathways	ko04390	154	3	7161	29	PARD3,CTNNA2,PPP2R2B
2.387e-02	-3.74	parotid	COSMIC cancer mutations	parotid	578	5	16828	48	TNIK,ERBB4,NTRK2,LRP1B,RYR3
2.391e-02	-3.73	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-NK-T_cell_lymphoma	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-NK-T_cell_lymphoma	217	3	16828	48	DTNA,MGAT4C,PLCB1
2.400e-02	-3.73	spindle	COSMIC cancer mutations	spindle	386	4	16828	48	TRPM3,CTNND2,CPE,PCDH9
2.401e-02	-3.73	ERBIN (erbb2 interacting protein)	protein interactions	55914	241	3	19454	50	PARD3,CTNND2,NTRK2
2.407e-02	-3.73	Villin headpiece domain	gene3d domains	1.10.950.10	8	1	14470	44	ABLIM1
2.407e-02	-3.73	Glycosyl transferase family 10, C-terminal domain	gene3d domains	3.40.50.11660	8	1	14470	44	FUT9
2.407e-02	-3.73	Guanylate Kinase phosphate binding domain	gene3d domains	3.30.63.10	8	1	14470	44	MAGI2
2.411e-02	-3.73	localization	biological process	GO:0051179	4474	19	18204	50	NRXN1,GPM6A,SLC1A2,LRP1B,GFAP,TRPM3,APOE,NTRK2,PITPNC1,CLU,RYR3,ANK2,PARD3,CPE,ERBB4,PLCB1,MAGI2,TNIK,FMN2
2.420e-02	-3.72	ACTG1 (actin gamma 1)	protein interactions	71	429	4	19454	50	APOE,TNIK,ABLIM1,FMN2
2.424e-02	-3.72	Long-term depression	KEGG pathways	ko04730	60	2	7161	29	PRKG1,PLCB1
2.424e-02	-3.72	Long-term depression	KEGG pathways	hsa04730	60	2	7161	29	PLCB1,PRKG1
2.435e-02	-3.72	WWC1 (WW and C2 domain containing 1)	protein interactions	23286	94	2	19454	50	TNIK,ABLIM1
2.435e-02	-3.72	TTR (transthyretin)	protein interactions	7276	94	2	19454	50	CTNND2,CLU
2.435e-02	-3.72	FOXP4 (forkhead box P4)	protein interactions	116113	94	2	19454	50	NFIA,SOX5
2.435e-02	-3.72	QSER1 (glutamine and serine rich 1)	protein interactions	79832	94	2	19454	50	SOX5,NFIA
2.439e-02	-3.71	regulation of growth	biological process	GO:0040008	603	5	18204	50	ERBB4,NRG3,TNC,APOE,PLCB1
2.446e-02	-3.71	macrophage proliferation	biological process	GO:0061517	9	1	18204	50	CLU
2.446e-02	-3.71	positive regulation of synapse maturation	biological process	GO:0090129	9	1	18204	50	NRXN1
2.446e-02	-3.71	L-fucose metabolic process	biological process	GO:0042354	9	1	18204	50	FUT9
2.446e-02	-3.71	negative regulation of cellular extravasation	biological process	GO:0002692	9	1	18204	50	PLCB1
2.446e-02	-3.71	sterol catabolic process	biological process	GO:0016127	9	1	18204	50	APOE
2.446e-02	-3.71	SA node cell to atrial cardiac muscle cell communication	biological process	GO:0086070	9	1	18204	50	ANK2
2.446e-02	-3.71	interleukin-12-mediated signaling pathway	biological process	GO:0035722	9	1	18204	50	PLCB1
2.446e-02	-3.71	hindbrain radial glia guided cell migration	biological process	GO:0021932	9	1	18204	50	CTNNA2
2.446e-02	-3.71	fucose catabolic process	biological process	GO:0019317	9	1	18204	50	FUT9
2.446e-02	-3.71	L-fucose catabolic process	biological process	GO:0042355	9	1	18204	50	FUT9
2.446e-02	-3.71	release of sequestered calcium ion into cytosol by sarcoplasmic reticulum	biological process	GO:0014808	9	1	18204	50	RYR3
2.446e-02	-3.71	microglial cell proliferation	biological process	GO:0061518	9	1	18204	50	CLU
2.446e-02	-3.71	negative regulation of actin nucleation	biological process	GO:0051126	9	1	18204	50	CTNNA2
2.446e-02	-3.71	cholesterol catabolic process	biological process	GO:0006707	9	1	18204	50	APOE
2.446e-02	-3.71	mesenchymal-epithelial cell signaling	biological process	GO:0060638	9	1	18204	50	TNC
2.450e-02	-3.71	upper_arm	COSMIC cancer mutations	upper_arm	582	5	16828	48	ERBB4,PLCB1,FUT9,FMN2,LRP1B
2.455e-02	-3.71	Neuronal System	REACTOME pathways	R-HSA-112316	349	4	10285	33	ADCY2,SLC1A2,PLCB1,NRXN1
2.460e-02	-3.70	cellular localization	biological process	GO:0051641	2660	13	18204	50	ERBB4,CPE,TNIK,FMN2,MAGI2,LRP1B,GFAP,NRXN1,SLC1A2,CLU,ANK2,PARD3,APOE
2.461e-02	-3.70	myofibril	cellular component	GO:0030016	239	3	19108	50	NEBL,RYR3,ANK2
2.470e-02	-3.70	EGF_1	prosite domains	PS00022	174	3	12186	44	TNC,LRP1B,NRG3
2.483e-02	-3.70	breast-carcinoma-HER-positive_carcinoma	COSMIC cancer mutations	breast-carcinoma-HER-positive_carcinoma	2025	11	16828	48	PPP2R2B,ERBB4,CNTN1,ABLIM1,MAGI2,TNC,RORA,RBMS3,GPC5,NRG3,NTRK2
2.483e-02	-3.70	HER-positive_carcinoma	COSMIC cancer mutations	HER-positive_carcinoma	2025	11	16828	48	PPP2R2B,ABLIM1,ERBB4,CNTN1,MAGI2,TNC,RBMS3,RORA,GPC5,NRG3,NTRK2
2.487e-02	-3.69	positive regulation of lipid biosynthetic process	biological process	GO:0046889	89	2	18204	50	SORBS1,APOE
2.497e-02	-3.69	Alzheimers Disease	WikiPathways	WP2059	148	3	5310	23	PLCB1,RYR3,APOE
2.501e-02	-3.69	NA_DICARBOXYL_SYMP_2	prosite domains	PS00714	7	1	12186	44	SLC1A2
2.501e-02	-3.69	NA_DICARBOXYL_SYMP_1	prosite domains	PS00713	7	1	12186	44	SLC1A2
2.501e-02	-3.69	lung-carcinoma-mixed_small_cell_carcinoma-adenocarcinoma	COSMIC cancer mutations	lung-carcinoma-mixed_small_cell_carcinoma-adenocarcinoma	86	2	16828	48	ANK2,LRP1B
2.531e-02	-3.68	uveal_tract	COSMIC cancer mutations	uveal_tract	587	5	16828	48	PCDH9,CPE,TRPM3,CTNND2,ADCY2
2.532e-02	-3.68	SOCS2 (suppressor of cytokine signaling 2)	protein interactions	8835	96	2	19454	50	NTRK2,ERBB4
2.534e-02	-3.68	G-Protein Signaling Through Tubby Proteins	SMPDB pathways	SMP0089843	7	1	1369	5	PLCB1
2.534e-02	-3.68	Vasopressin Regulation of Water Homeostasis	SMPDB pathways	SMP0000322	7	1	1369	5	ADCY2
2.534e-02	-3.68	g-Secretase Mediated ErbB4 Signalling Pathway	SMPDB pathways	SMP0089975	7	1	1369	5	ERBB4
2.539e-02	-3.67	Downregulation of ERBB4 signaling	REACTOME pathways	R-HSA-1253288	8	1	10285	33	ERBB4
2.539e-02	-3.67	Free fatty acids regulate insulin secretion	REACTOME pathways	R-HSA-400451	8	1	10285	33	PLCB1
2.539e-02	-3.67	Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion	REACTOME pathways	R-HSA-434316	8	1	10285	33	PLCB1
2.539e-02	-3.67	Release of Hh-Np from the secreting cell	REACTOME pathways	R-HSA-5362798	8	1	10285	33	GPC5
2.541e-02	-3.67	Vbp1 (von Hippel-Lindau binding protein 1)	protein interactions	22327	10	1	19454	50	ABLIM1
2.541e-02	-3.67	PTPRT (protein tyrosine phosphatase receptor type T)	protein interactions	11122	10	1	19454	50	ERBB4
2.541e-02	-3.67	EREG (epiregulin)	protein interactions	2069	10	1	19454	50	ERBB4
2.541e-02	-3.67	SLC8A2 (solute carrier family 8 member A2)	protein interactions	6543	10	1	19454	50	GPM6A
2.541e-02	-3.67	CALB2 (calbindin 2)	protein interactions	794	10	1	19454	50	GPM6A
2.541e-02	-3.67	GSG1 (germ cell associated 1)	protein interactions	83445	10	1	19454	50	PITPNC1
2.541e-02	-3.67	CHRDL1 (chordin like 1)	protein interactions	91851	10	1	19454	50	LRP1B
2.541e-02	-3.67	Smurf2 (SMAD specific E3 ubiquitin protein ligase 2)	protein interactions	66313	10	1	19454	50	GLIS3
2.541e-02	-3.67	DEFA1B (defensin alpha 1B)	protein interactions	728358	10	1	19454	50	PPP2R2B
2.541e-02	-3.67	ZNF563 (zinc finger protein 563)	protein interactions	147837	10	1	19454	50	LRP1B
2.541e-02	-3.67	SERPINB11 (serpin family B member 11)	protein interactions	89778	10	1	19454	50	CPE
2.541e-02	-3.67	P2rx7 (purinergic receptor P2X 7)	protein interactions	29665	10	1	19454	50	PTPRZ1
2.553e-02	-3.67	calcium ion homeostasis	biological process	GO:0055074	231	3	18204	50	RYR3,ANK2,APOE
2.555e-02	-3.67	mixed_small_cell_carcinoma-adenocarcinoma	COSMIC cancer mutations	mixed_small_cell_carcinoma-adenocarcinoma	87	2	16828	48	LRP1B,ANK2
2.581e-02	-3.66	FGG (fibrinogen gamma chain)	protein interactions	2266	97	2	19454	50	LRP1B,PPP2R2B
2.585e-02	-3.66	NCOR2 (nuclear receptor corepressor 2)	protein interactions	9612	248	3	19454	50	TNIK,NFIA,SOX5
2.585e-02	-3.66	ABL1 (ABL proto-oncogene 1, non-receptor tyrosine kinase)	protein interactions	25	248	3	19454	50	CTNND2,ERBB4,SORBS1
2.587e-02	-3.65	perineuronal net	cellular component	GO:0072534	10	1	19108	50	PTPRZ1
2.612e-02	-3.65	GAN (gigaxonin)	protein interactions	8139	249	3	19454	50	GFAP,CTNNA2,PLCB1
2.622e-02	-3.64	neurotrophin binding	molecular function	GO:0043121	10	1	18094	48	NTRK2
2.622e-02	-3.64	phosphatidylinositol transfer activity	molecular function	GO:0008526	10	1	18094	48	PITPNC1
2.625e-02	-3.64	NK-T_cell_lymphoma	COSMIC cancer mutations	NK-T_cell_lymphoma	225	3	16828	48	DTNA,PLCB1,MGAT4C
2.631e-02	-3.64	FRAS1 (Fraser extracellular matrix complex subunit 1)	protein interactions	80144	98	2	19454	50	MGAT4C,HPSE2
2.631e-02	-3.64	Calcium Regulation in the Cardiac Cell	WikiPathways	WP536	151	3	5310	23	ADCY2,RYR3,RGS6
2.645e-02	-3.63	protein tetramerization	biological process	GO:0051262	92	2	18204	50	RYR3,TRPM3
2.646e-02	-3.63	human chr9q33.1	chromosome location	human chr9q33.1	14	1	26134	50	TNC
2.646e-02	-3.63	human chr2p16.3	chromosome location	human chr2p16.3	14	1	26134	50	NRXN1
2.646e-02	-3.63	human chr6q16.1	chromosome location	human chr6q16.1	14	1	26134	50	FUT9
2.666e-02	-3.62	MIR	pfam domains	PF02815	10	1	17795	48	RYR3
2.666e-02	-3.62	PAS_3	pfam domains	PF08447	10	1	17795	48	NPAS3
2.668e-02	-3.62	MIR_motif	interpro domains	IPR016093	10	1	18521	50	RYR3
2.668e-02	-3.62	MIR_dom_sf	interpro domains	IPR036300	10	1	18521	50	RYR3
2.668e-02	-3.62	PAS_fold_3	interpro domains	IPR013655	10	1	18521	50	NPAS3
2.680e-02	-3.62	TNKS (tankyrase)	protein interactions	8658	99	2	19454	50	TNIK,PCDH9
2.690e-02	-3.62	chemical synaptic transmission	biological process	GO:0007268	415	4	18204	50	SLC1A2,NRXN1,APOE,DTNA
2.690e-02	-3.62	anterograde trans-synaptic signaling	biological process	GO:0098916	415	4	18204	50	DTNA,SLC1A2,APOE,NRXN1
2.705e-02	-3.61	LIM_DOMAIN_1	prosite domains	PS00478	71	2	12186	44	ABLIM1,NEBL
2.705e-02	-3.61	LIM_DOMAIN_2	prosite domains	PS50023	71	2	12186	44	NEBL,ABLIM1
2.714e-02	-3.61	substrate-independent telencephalic tangential interneuron migration	biological process	GO:0021843	10	1	18204	50	NRG3
2.714e-02	-3.61	negative regulation of sterol biosynthetic process	biological process	GO:0106119	10	1	18204	50	APOE
2.714e-02	-3.61	learned vocalization behavior or vocal learning	biological process	GO:0098598	10	1	18204	50	NRXN1
2.714e-02	-3.61	postsynaptic membrane assembly	biological process	GO:0097104	10	1	18204	50	NRXN1
2.714e-02	-3.61	regulation of mesenchymal stem cell differentiation	biological process	GO:2000739	10	1	18204	50	SOX5
2.714e-02	-3.61	nitric oxide-cGMP-mediated signaling	biological process	GO:0038060	10	1	18204	50	APOE
2.714e-02	-3.61	retinal rod cell development	biological process	GO:0046548	10	1	18204	50	NTRK2
2.714e-02	-3.61	podocyte development	biological process	GO:0072015	10	1	18204	50	MAGI2
2.714e-02	-3.61	mitochondrial fragmentation involved in apoptotic process	biological process	GO:0043653	10	1	18204	50	ERBB4
2.714e-02	-3.61	action potential propagation	biological process	GO:0098870	10	1	18204	50	NTRK2
2.714e-02	-3.61	release of sequestered calcium ion into cytosol by endoplasmic reticulum	biological process	GO:1903514	10	1	18204	50	RYR3
2.714e-02	-3.61	trans-synaptic signaling, modulating synaptic transmission	biological process	GO:0099550	10	1	18204	50	NTRK2
2.714e-02	-3.61	establishment of centrosome localization	biological process	GO:0051660	10	1	18204	50	PARD3
2.714e-02	-3.61	cAMP biosynthetic process	biological process	GO:0006171	10	1	18204	50	ADCY2
2.714e-02	-3.61	negative regulation of cholesterol biosynthetic process	biological process	GO:0045541	10	1	18204	50	APOE
2.714e-02	-3.61	cellular response to brain-derived neurotrophic factor stimulus	biological process	GO:1990416	10	1	18204	50	NTRK2
2.714e-02	-3.61	regulation of CoA-transferase activity	biological process	GO:1905918	10	1	18204	50	APOE
2.714e-02	-3.61	regulation of behavioral fear response	biological process	GO:2000822	10	1	18204	50	APOE
2.714e-02	-3.61	neuronal action potential propagation	biological process	GO:0019227	10	1	18204	50	NTRK2
2.714e-02	-3.61	somatic stem cell division	biological process	GO:0048103	10	1	18204	50	FUT9
2.714e-02	-3.61	cellular response to cocaine	biological process	GO:0071314	10	1	18204	50	SLC1A2
2.714e-02	-3.61	high-density lipoprotein particle assembly	biological process	GO:0034380	10	1	18204	50	APOE
2.714e-02	-3.61	postsynaptic density assembly	biological process	GO:0097107	10	1	18204	50	NRXN1
2.714e-02	-3.61	substrate-independent telencephalic tangential migration	biological process	GO:0021826	10	1	18204	50	NRG3
2.719e-02	-3.60	Tyr_kinase_AS	interpro domains	IPR008266	95	2	18521	50	NTRK2,ERBB4
2.719e-02	-3.60	EGF-type_Asp/Asn_hydroxyl_site	interpro domains	IPR000152	95	2	18521	50	NRXN1,LRP1B
2.719e-02	-3.60	response to organic cyclic compound	biological process	GO:0014070	843	6	18204	50	SLC1A2,PLCB1,RORA,ADCY2,RYR3,TNC
2.731e-02	-3.60	APBA1 (amyloid beta precursor protein binding family A member 1)	protein interactions	320	100	2	19454	50	NRXN1,ABLIM1
2.731e-02	-3.60	EDEM2 (ER degradation enhancing alpha-mannosidase like protein 2)	protein interactions	55741	100	2	19454	50	CLU,HPSE2
2.734e-02	-3.60	contractile muscle fiber	cellular component	GO:0043292	249	3	19108	50	ANK2,NEBL,RYR3
2.743e-02	-3.60	cGMP-PKG signaling pathway	KEGG pathways	hsa04022	163	3	7161	29	PRKG1,ADCY2,PLCB1
2.743e-02	-3.60	cGMP-PKG signaling pathway	KEGG pathways	ko04022	163	3	7161	29	ADCY2,PLCB1,PRKG1
2.756e-02	-3.59	muscle contraction	biological process	GO:0006936	238	3	18204	50	DTNA,RYR3,ANK2
2.756e-02	-3.59	protein localization to cell periphery	biological process	GO:1990778	238	3	18204	50	ANK2,ERBB4,TNIK
2.776e-02	-3.58	LMO2 (LIM domain only 2)	protein interactions	4005	255	3	19454	50	SOX5,GFAP,PRKG1
2.777e-02	-3.58	adrenal_gland-adrenal_gland-adrenal_cortical_adenoma-aldosterone_producing	COSMIC cancer mutations	adrenal_gland-adrenal_gland-adrenal_cortical_adenoma-aldosterone_producing	91	2	16828	48	LRP1B,ADCY2
2.781e-02	-3.58	PRKCG (protein kinase C gamma)	protein interactions	5582	101	2	19454	50	GFAP,PARD3
2.781e-02	-3.58	EVPL (envoplakin)	protein interactions	2125	101	2	19454	50	NKAIN3,PPP2R2B
2.792e-02	-3.58	Cobll1 (Cobl-like 1)	protein interactions	319876	11	1	19454	50	ABLIM1
2.792e-02	-3.58	SCN3A (sodium voltage-gated channel alpha subunit 3)	protein interactions	6328	11	1	19454	50	CNTN1
2.792e-02	-3.58	SYTL1 (synaptotagmin like 1)	protein interactions	84958	11	1	19454	50	NRXN1
2.792e-02	-3.58	IRAG1 (inositol 1,4,5-triphosphate receptor associated 1)	protein interactions	10335	11	1	19454	50	PRKG1
2.792e-02	-3.58	MSRB1 (methionine sulfoxide reductase B1)	protein interactions	51734	11	1	19454	50	CLU
2.792e-02	-3.58	ADCY5 (adenylate cyclase 5)	protein interactions	111	11	1	19454	50	ADCY2
2.792e-02	-3.58	SYN3 (synapsin III)	protein interactions	8224	11	1	19454	50	GPM6A
2.792e-02	-3.58	NTS (neurotensin)	protein interactions	4922	11	1	19454	50	CPE
2.793e-02	-3.58	large_intestine-colon-carcinoma	COSMIC cancer mutations	large_intestine-colon-carcinoma	2612	13	16828	48	NRG3,GPC5,PTPRZ1,RORA,PCDH9,TNC,PARD3,CPE,LRP1B,NRXN1,ADCY2,FMN2,TRPM3
2.807e-02	-3.57	calcium ion transmembrane import into cytosol	biological process	GO:0097553	95	2	18204	50	RYR3,PLCB1
2.807e-02	-3.57	cardiac muscle cell differentiation	biological process	GO:0055007	95	2	18204	50	NEBL,PRKG1
2.831e-02	-3.56	Alzheimer's disease	KEGG pathways	ko05010	165	3	7161	29	APOE,RYR3,PLCB1
2.831e-02	-3.56	Alzheimer's disease	KEGG pathways	hsa05010	165	3	7161	29	APOE,PLCB1,RYR3
2.832e-02	-3.56	PDLIM7 (PDZ and LIM domain 7)	protein interactions	9260	257	3	19454	50	PARD3,ABLIM1,GFAP
2.832e-02	-3.56	human chr10p12.31	chromosome location	human chr10p12.31	15	1	26134	50	NEBL
2.832e-02	-3.56	human chr8q12.3	chromosome location	human chr8q12.3	15	1	26134	50	NKAIN3
2.832e-02	-3.56	GRAP2 (GRB2 related adaptor protein 2)	protein interactions	9402	102	2	19454	50	ERBB4,GFAP
2.832e-02	-3.56	HP (haptoglobin)	protein interactions	3240	102	2	19454	50	CLU,PPP2R2B
2.842e-02	-3.56	interstitial matrix	cellular component	GO:0005614	11	1	19108	50	TNC
2.851e-02	-3.56	PROTEIN_KINASE_DOM	prosite domains	PS50011	480	5	12186	44	MAPK10,PRKG1,ERBB4,TNIK,NTRK2
2.852e-02	-3.56	Terminal pathway of complement	REACTOME pathways	R-HSA-166665	9	1	10285	33	CLU
2.853e-02	-3.56	HP	prosite domains	PS51089	8	1	12186	44	ABLIM1
2.853e-02	-3.56	eye	COSMIC cancer mutations	eye	606	5	16828	48	CPE,PCDH9,TRPM3,ADCY2,CTNND2
2.862e-02	-3.55	negative regulation of response to wounding	biological process	GO:1903035	96	2	18204	50	PRKG1,APOE
2.876e-02	-3.55	metal ion transport	biological process	GO:0030001	630	5	18204	50	ANK2,RYR3,GPM6A,TRPM3,PLCB1
2.880e-02	-3.55	sulfur amino acid transmembrane transporter activity	molecular function	GO:0000099	11	1	18094	48	SLC1A2
2.880e-02	-3.55	acetylcholine receptor binding	molecular function	GO:0033130	11	1	18094	48	NRXN1
2.884e-02	-3.55	ZDHHC5 (zinc finger DHHC-type palmitoyltransferase 5)	protein interactions	25921	103	2	19454	50	NTRK2,PARD3
2.889e-02	-3.54	MARK2 (microtubule affinity regulating kinase 2)	protein interactions	2011	259	3	19454	50	DTNA,PARD3,PPP2R2B
2.891e-02	-3.54	aldosterone_producing	COSMIC cancer mutations	aldosterone_producing	93	2	16828	48	ADCY2,LRP1B
2.892e-02	-3.54	Mizolastine H1-Antihistamine Action	SMPDB pathways	SMP0060230	8	1	1369	5	PLCB1
2.892e-02	-3.54	Buclizine H1-Antihistamine Action	SMPDB pathways	SMP0058964	8	1	1369	5	PLCB1
2.892e-02	-3.54	Mebhydrolin H1-Antihistamine Action	SMPDB pathways	SMP0061052	8	1	1369	5	PLCB1
2.892e-02	-3.54	Mepyramine H1-Antihistamine Action	SMPDB pathways	SMP0057583	8	1	1369	5	PLCB1
2.892e-02	-3.54	Clocinizine H1-Antihistamine Action	SMPDB pathways	SMP0062788	8	1	1369	5	PLCB1
2.892e-02	-3.54	Levocetirizine H1-Antihistamine Action	SMPDB pathways	SMP0059114	8	1	1369	5	PLCB1
2.892e-02	-3.54	Mequitazine H1-Antihistamine Action	SMPDB pathways	SMP0059720	8	1	1369	5	PLCB1
2.892e-02	-3.54	Fexofenadine H1-Antihistamine Action	SMPDB pathways	SMP0060218	8	1	1369	5	PLCB1
2.892e-02	-3.54	Bepotastine H1-Antihistamine Action	SMPDB pathways	SMP0060058	8	1	1369	5	PLCB1
2.892e-02	-3.54	Quifenadine H1-Antihistamine Action	SMPDB pathways	SMP0060743	8	1	1369	5	PLCB1
2.892e-02	-3.54	Phenyltoloxamine H1-Antihistamine Action	SMPDB pathways	SMP0058916	8	1	1369	5	PLCB1
2.892e-02	-3.54	Astemizole H1-Antihistamine Action	SMPDB pathways	SMP0059897	8	1	1369	5	PLCB1
2.892e-02	-3.54	Flunarizine H1-Antihistamine Action	SMPDB pathways	SMP0061047	8	1	1369	5	PLCB1
2.892e-02	-3.54	Epinastine H1-Antihistamine Action	SMPDB pathways	SMP0061191	8	1	1369	5	PLCB1
2.892e-02	-3.54	Doxepin H1-Antihistamine Action	SMPDB pathways	SMP0059872	8	1	1369	5	PLCB1
2.892e-02	-3.54	Emedastine H1-Antihistamine Action	SMPDB pathways	SMP0061040	8	1	1369	5	PLCB1
2.892e-02	-3.54	Promethazine H1-Antihistamine Action	SMPDB pathways	SMP0059211	8	1	1369	5	PLCB1
2.892e-02	-3.54	Quetiapine H1-Antihistamine Action	SMPDB pathways	SMP0062884	8	1	1369	5	PLCB1
2.892e-02	-3.54	Latrepirdine H1-Antihistamine Action	SMPDB pathways	SMP0062623	8	1	1369	5	PLCB1
2.892e-02	-3.54	Azatadine H1-Antihistamine Action	SMPDB pathways	SMP0059865	8	1	1369	5	PLCB1
2.892e-02	-3.54	Homochlorcyclizine H1-Antihistamine Action	SMPDB pathways	SMP0062795	8	1	1369	5	PLCB1
2.892e-02	-3.54	Diphenhydramine H1-Antihistamine Action	SMPDB pathways	SMP0058785	8	1	1369	5	PLCB1
2.892e-02	-3.54	Terfenadine H1-Antihistamine Action	SMPDB pathways	SMP0060208	8	1	1369	5	PLCB1
2.892e-02	-3.54	Cyclizine H1-Antihistamine Action	SMPDB pathways	SMP0058923	8	1	1369	5	PLCB1
2.892e-02	-3.54	Cyproheptadine H1-Antihistamine Action	SMPDB pathways	SMP0059694	8	1	1369	5	PLCB1
2.892e-02	-3.54	Deptropine H1-Antihistamine Action	SMPDB pathways	SMP0062883	8	1	1369	5	PLCB1
2.892e-02	-3.54	Thenyldiamine H1-Antihistamine Action	SMPDB pathways	SMP0062624	8	1	1369	5	PLCB1
2.892e-02	-3.54	Rupatadine H1-Antihistamine Action	SMPDB pathways	SMP0060235	8	1	1369	5	PLCB1
2.892e-02	-3.54	Betahistine H1-Antihistamine Action	SMPDB pathways	SMP0060744	8	1	1369	5	PLCB1
2.892e-02	-3.54	Ebastine H1-Antihistamine Action	SMPDB pathways	SMP0060204	8	1	1369	5	PLCB1
2.892e-02	-3.54	Phenindamine H1-Antihistamine Action	SMPDB pathways	SMP0061190	8	1	1369	5	PLCB1
2.892e-02	-3.54	Thonzylamine H1-Antihistamine Action	SMPDB pathways	SMP0058769	8	1	1369	5	PLCB1
2.892e-02	-3.54	Methdilazine H1-Antihistamine Action	SMPDB pathways	SMP0059730	8	1	1369	5	PLCB1
2.892e-02	-3.54	Antazoline H1-Antihistamine Action	SMPDB pathways	SMP0057584	8	1	1369	5	PLCB1
2.892e-02	-3.54	Tritoqualine H1-Antihistamine Action	SMPDB pathways	SMP0062895	8	1	1369	5	PLCB1
2.892e-02	-3.54	Loratadine H1-Antihistamine Action	SMPDB pathways	SMP0060195	8	1	1369	5	PLCB1
2.892e-02	-3.54	Methapyrilene H1-Antihistamine Action	SMPDB pathways	SMP0058741	8	1	1369	5	PLCB1
2.892e-02	-3.54	Bilastine H1-Antihistamine Action	SMPDB pathways	SMP0060170	8	1	1369	5	PLCB1
2.892e-02	-3.54	Olopatadine H1-Antihistamine Action	SMPDB pathways	SMP0060740	8	1	1369	5	PLCB1
2.892e-02	-3.54	Lysophosphatidic Acid LPA3 Signalling	SMPDB pathways	SMP0063755	8	1	1369	5	PLCB1
2.892e-02	-3.54	Hydroxyethylpromethazine H1-Antihistamine Action	SMPDB pathways	SMP0059710	8	1	1369	5	PLCB1
2.892e-02	-3.54	Chlorphenoxamine H1-Antihistamine Action	SMPDB pathways	SMP0058903	8	1	1369	5	PLCB1
2.892e-02	-3.54	Acrivastine H1-Antihistamine Action	SMPDB pathways	SMP0059881	8	1	1369	5	PLCB1
2.892e-02	-3.54	Phenbenzamine H1-Antihistamine Action	SMPDB pathways	SMP0059702	8	1	1369	5	PLCB1
2.892e-02	-3.54	Pimethixene H1-Antihistamine Action	SMPDB pathways	SMP0062886	8	1	1369	5	PLCB1
2.892e-02	-3.54	Cetirizine H1-Antihistamine Action	SMPDB pathways	SMP0059058	8	1	1369	5	PLCB1
2.892e-02	-3.54	Dexbrompheniramine H1-Antihistamine Action	SMPDB pathways	SMP0057580	8	1	1369	5	PLCB1
2.892e-02	-3.54	Levocabastine H1-Antihistamine Action	SMPDB pathways	SMP0060224	8	1	1369	5	PLCB1
2.892e-02	-3.54	Brompheniramine H1-Antihistamine Action	SMPDB pathways	SMP0057579	8	1	1369	5	PLCB1
2.892e-02	-3.54	Mirtazapine H1-Antihistamine Action	SMPDB pathways	SMP0062885	8	1	1369	5	PLCB1
2.892e-02	-3.54	Doxylamine H1-Antihistamine Action	SMPDB pathways	SMP0058803	8	1	1369	5	PLCB1
2.892e-02	-3.54	Clemastine H1-Antihistamine Action	SMPDB pathways	SMP0058891	8	1	1369	5	PLCB1
2.892e-02	-3.54	Alcaftadine H1-Antihistamine Action	SMPDB pathways	SMP0062881	8	1	1369	5	PLCB1
2.892e-02	-3.54	Oxomemazine H1-Antihistamine Action	SMPDB pathways	SMP0059738	8	1	1369	5	PLCB1
2.892e-02	-3.54	Bamipine H1-Antihistamine Action	SMPDB pathways	SMP0062882	8	1	1369	5	PLCB1
2.892e-02	-3.54	Tripelennamine H1-Antihistamine Action	SMPDB pathways	SMP0057587	8	1	1369	5	PLCB1
2.892e-02	-3.54	Diphenylpyraline H1-Antihistamine Action	SMPDB pathways	SMP0058908	8	1	1369	5	PLCB1
2.892e-02	-3.54	Carbinoxamine H1-Antihistamine Action	SMPDB pathways	SMP0058797	8	1	1369	5	PLCB1
2.892e-02	-3.54	Propiomazine H1-Antihistamine Action	SMPDB pathways	SMP0062625	8	1	1369	5	PLCB1
2.892e-02	-3.54	Cinnarizine H1-Antihistamine Action	SMPDB pathways	SMP0059110	8	1	1369	5	PLCB1
2.892e-02	-3.54	Hydroxyzine H1-Antihistamine Action	SMPDB pathways	SMP0058936	8	1	1369	5	PLCB1
2.892e-02	-3.54	Embramine H1-Antihistamine Action	SMPDB pathways	SMP0062622	8	1	1369	5	PLCB1
2.892e-02	-3.54	Intracellular Signalling Through Prostacyclin Receptor and Prostacyclin	SMPDB pathways	SMP0000354	8	1	1369	5	ADCY2
2.892e-02	-3.54	Tolpropamine H1-Antihistamine Action	SMPDB pathways	SMP0062621	8	1	1369	5	PLCB1
2.892e-02	-3.54	Meclizine H1-Antihistamine Action	SMPDB pathways	SMP0058956	8	1	1369	5	PLCB1
2.892e-02	-3.54	Histamine H1 Receptor Activation	SMPDB pathways	SMP0063452	8	1	1369	5	PLCB1
2.892e-02	-3.54	Alimemazine H1-Antihistamine Action	SMPDB pathways	SMP0059689	8	1	1369	5	PLCB1
2.892e-02	-3.54	Bromodiphenhydramine H1-Antihistamine Action	SMPDB pathways	SMP0058813	8	1	1369	5	PLCB1
2.892e-02	-3.54	Thiazinamium H1-Antihistamine Action	SMPDB pathways	SMP0060742	8	1	1369	5	PLCB1
2.892e-02	-3.54	Oxatomide H1-Antihistamine Action	SMPDB pathways	SMP0059044	8	1	1369	5	PLCB1
2.892e-02	-3.54	Azelastine H1-Antihistamine Action	SMPDB pathways	SMP0060741	8	1	1369	5	PLCB1
2.892e-02	-3.54	Desloratadine H1-Antihistamine Action	SMPDB pathways	SMP0060201	8	1	1369	5	PLCB1
2.892e-02	-3.54	Orphenadrine H1-Antihistamine Action	SMPDB pathways	SMP0058808	8	1	1369	5	PLCB1
2.892e-02	-3.54	Chlorcyclizine H1-Antihistamine Action	SMPDB pathways	SMP0058931	8	1	1369	5	PLCB1
2.892e-02	-3.54	Ketotifen H1-Antihistamine Action	SMPDB pathways	SMP0059868	8	1	1369	5	PLCB1
2.892e-02	-3.54	Isothipendyl H1-Antihistamine Action	SMPDB pathways	SMP0059716	8	1	1369	5	PLCB1
2.892e-02	-3.54	Chlorphenamine H1-Antihistamine Action	SMPDB pathways	SMP0056661	8	1	1369	5	PLCB1
2.892e-02	-3.54	Pheniramine H1-Antihistamine Action	SMPDB pathways	SMP0056662	8	1	1369	5	PLCB1
2.892e-02	-3.54	Fenethazine H1-Antihistamine Action	SMPDB pathways	SMP0059707	8	1	1369	5	PLCB1
2.892e-02	-3.54	Talastine H1-Antihistamine Action	SMPDB pathways	SMP0057586	8	1	1369	5	PLCB1
2.892e-02	-3.54	Temelastine H1-Antihistamine Action	SMPDB pathways	SMP0062880	8	1	1369	5	PLCB1
2.892e-02	-3.54	Thenalidine H1-Antihistamine Action	SMPDB pathways	SMP0062894	8	1	1369	5	PLCB1
2.892e-02	-3.54	Chloropyramine H1-Antihistamine Action	SMPDB pathways	SMP0057585	8	1	1369	5	PLCB1
2.892e-02	-3.54	Histapyrrodine H1-Antihistamine Action	SMPDB pathways	SMP0058732	8	1	1369	5	PLCB1
2.892e-02	-3.54	Dexchlorpheniramine H1-Antihistamine Action	SMPDB pathways	SMP0056811	8	1	1369	5	PLCB1
2.892e-02	-3.54	Dimetindene H1-Antihistamine Action	SMPDB pathways	SMP0057582	8	1	1369	5	PLCB1
2.892e-02	-3.54	Triprolidine H1-Antihistamine Action	SMPDB pathways	SMP0057581	8	1	1369	5	PLCB1
2.892e-02	-3.54	Pyrrobutamine H1-Antihistamine Action	SMPDB pathways	SMP0062887	8	1	1369	5	PLCB1
2.907e-02	-3.54	viral process	biological process	GO:0016032	243	3	18204	50	NFIA,MGAT4C,APOE
2.917e-02	-3.53	positive regulation of JNK cascade	biological process	GO:0046330	97	2	18204	50	PLCB1,TNIK
2.917e-02	-3.53	amino acid transmembrane transport	biological process	GO:0003333	97	2	18204	50	GFAP,SLC1A2
2.927e-02	-3.53	Axon guidance	REACTOME pathways	R-HSA-422475	549	5	10285	33	ERBB4,ABLIM1,ANK2,NRG3,CNTN1
2.928e-02	-3.53	ZU5	pfam domains	PF00791	11	1	17795	48	ANK2
2.931e-02	-3.53	Tyr_kinase_rcpt_2_CS	interpro domains	IPR002011	11	1	18521	50	NTRK2
2.937e-02	-3.53	metal ion transmembrane transporter activity	molecular function	GO:0046873	442	4	18094	48	GPM6A,RYR3,SLC1A2,TRPM3
2.937e-02	-3.53	regulation of neuron apoptotic process	biological process	GO:0043523	244	3	18204	50	CLU,PTPRZ1,NTRK2
2.946e-02	-3.52	DIRAS3 (DIRAS family GTPase 3)	protein interactions	9077	261	3	19454	50	DTNA,FMN2,PARD3
2.958e-02	-3.52	Myometrial Relaxation and Contraction Pathways	WikiPathways	WP289	158	3	5310	23	ADCY2,RYR3,RGS6
2.968e-02	-3.52	negative regulation of response to external stimulus	biological process	GO:0032102	428	4	18204	50	APOE,RORA,PRKG1,CTNNA2
2.980e-02	-3.51	organic substance transport	biological process	GO:0071702	1881	10	18204	50	CLU,FMN2,ANK2,APOE,NTRK2,PITPNC1,LRP1B,GFAP,CPE,SLC1A2
2.981e-02	-3.51	cellular response to interleukin-12	biological process	GO:0071349	11	1	18204	50	PLCB1
2.981e-02	-3.51	physiological muscle hypertrophy	biological process	GO:0003298	11	1	18204	50	PRKG1
2.981e-02	-3.51	ectodermal placode morphogenesis	biological process	GO:0071697	11	1	18204	50	NRG3
2.981e-02	-3.51	egg activation	biological process	GO:0007343	11	1	18204	50	PLCB1
2.981e-02	-3.51	negative regulation of neuron migration	biological process	GO:2001223	11	1	18204	50	NRG3
2.981e-02	-3.51	glomerular epithelial cell development	biological process	GO:0072310	11	1	18204	50	MAGI2
2.981e-02	-3.51	positive regulation of acrosome reaction	biological process	GO:2000344	11	1	18204	50	PLCB1
2.981e-02	-3.51	regulation of Schwann cell proliferation	biological process	GO:0010624	11	1	18204	50	GFAP
2.981e-02	-3.51	interleukin-15-mediated signaling pathway	biological process	GO:0035723	11	1	18204	50	PLCB1
2.981e-02	-3.51	regulation of receptor catabolic process	biological process	GO:2000644	11	1	18204	50	APOE
2.981e-02	-3.51	L-aspartate transmembrane transport	biological process	GO:0070778	11	1	18204	50	SLC1A2
2.981e-02	-3.51	regulation of fear response	biological process	GO:1903365	11	1	18204	50	APOE
2.981e-02	-3.51	negative regulation of cholesterol metabolic process	biological process	GO:0090206	11	1	18204	50	APOE
2.981e-02	-3.51	physiological cardiac muscle hypertrophy	biological process	GO:0003301	11	1	18204	50	PRKG1
2.981e-02	-3.51	cellular response to caffeine	biological process	GO:0071313	11	1	18204	50	RYR3
2.981e-02	-3.51	Bergmann glial cell differentiation	biological process	GO:0060020	11	1	18204	50	GFAP
2.981e-02	-3.51	glutamate secretion	biological process	GO:0014047	11	1	18204	50	NTRK2
2.981e-02	-3.51	ectodermal placode formation	biological process	GO:0060788	11	1	18204	50	NRG3
2.981e-02	-3.51	negative regulation of platelet aggregation	biological process	GO:0090331	11	1	18204	50	PRKG1
2.981e-02	-3.51	cellular response to interleukin-15	biological process	GO:0071350	11	1	18204	50	PLCB1
2.981e-02	-3.51	cell growth involved in cardiac muscle cell development	biological process	GO:0061049	11	1	18204	50	PRKG1
2.981e-02	-3.51	L-glutamate import across plasma membrane	biological process	GO:0098712	11	1	18204	50	SLC1A2
2.988e-02	-3.51	IRF2BP2 (interferon regulatory factor 2 binding protein 2)	protein interactions	359948	105	2	19454	50	ERBB4,NFIA
2.999e-02	-3.51	positive regulation of neurogenesis	biological process	GO:0050769	246	3	18204	50	GFAP,PTPRZ1,NTRK2
3.020e-02	-3.50	Opioid Signalling	REACTOME pathways	R-HSA-111885	85	2	10285	33	ADCY2,PLCB1
3.028e-02	-3.50	phospholipid transport	biological process	GO:0015914	99	2	18204	50	APOE,PITPNC1
3.040e-02	-3.49	USP6NL (USP6 N-terminal like)	protein interactions	9712	106	2	19454	50	PARD3,NTRK2
3.042e-02	-3.49	HUDSXLRNA	prints domains	PR00961	7	1	5227	23	RBMS3
3.042e-02	-3.49	EDTRNSPORT	prints domains	PR00173	7	1	5227	23	SLC1A2
3.042e-02	-3.49	MMP25 (matrix metallopeptidase 25)	protein interactions	64386	12	1	19454	50	CLU
3.042e-02	-3.49	ART4 (ADP-ribosyltransferase 4 (inactive) (Dombrock blood group))	protein interactions	420	12	1	19454	50	GPM6A
3.042e-02	-3.49	PTPN20 (protein tyrosine phosphatase non-receptor type 20)	protein interactions	26095	12	1	19454	50	ERBB4
3.042e-02	-3.49	PLXNB3 (plexin B3)	protein interactions	5365	12	1	19454	50	MAGI2
3.042e-02	-3.49	MYBPHL (myosin binding protein H like)	protein interactions	343263	12	1	19454	50	GFAP
3.042e-02	-3.49	SMIM20 (small integral membrane protein 20)	protein interactions	389203	12	1	19454	50	ERBB4
3.042e-02	-3.49	Pard6b (par-6 family cell polarity regulator beta)	protein interactions	58220	12	1	19454	50	PARD3
3.042e-02	-3.49	INTS4P2 (integrator complex subunit 4 pseudogene 2)	protein interactions	644619	12	1	19454	50	GFAP
3.042e-02	-3.49	NTF4 (neurotrophin 4)	protein interactions	4909	12	1	19454	50	NTRK2
3.042e-02	-3.49	OAS2 (2'-5'-oligoadenylate synthetase 2)	protein interactions	4939	12	1	19454	50	PRKG1
3.042e-02	-3.49	KIF26A (kinesin family member 26A)	protein interactions	26153	12	1	19454	50	MAPK10
3.042e-02	-3.49	LMP-1 (latent membrane protein LMP-1)	protein interactions	3783750	12	1	19454	50	TNIK
3.056e-02	-3.49	Tight junction	KEGG pathways	ko04530	170	3	7161	29	PARD3,MAPK10,PPP2R2B
3.056e-02	-3.49	Tight junction	KEGG pathways	hsa04530	170	3	7161	29	PARD3,MAPK10,PPP2R2B
3.059e-02	-3.49	Epithelial cell signaling in Helicobacter pylori infection	KEGG pathways	ko05120	68	2	7161	29	PTPRZ1,MAPK10
3.059e-02	-3.49	Epithelial cell signaling in Helicobacter pylori infection	KEGG pathways	hsa05120	68	2	7161	29	PTPRZ1,MAPK10
3.085e-02	-3.48	response to alkaloid	biological process	GO:0043279	100	2	18204	50	RYR3,SLC1A2
3.097e-02	-3.47	HSPA5 (heat shock protein family A (Hsp70) member 5)	protein interactions	3309	1455	8	19454	50	GFAP,HPSE2,GPC5,PARD3,DTNA,APOE,LRP1B,CLU
3.107e-02	-3.47	MCAM (melanoma cell adhesion molecule)	protein interactions	4162	464	4	19454	50	PLCB1,CTNNA2,CNTN1,TNIK
3.138e-02	-3.46	adenylate cyclase binding	molecular function	GO:0008179	12	1	18094	48	ADCY2
3.138e-02	-3.46	activin receptor binding	molecular function	GO:0070697	12	1	18094	48	MAGI2
3.142e-02	-3.46	cholesterol homeostasis	biological process	GO:0042632	101	2	18204	50	APOE,RORA
3.142e-02	-3.46	regulation of glucose metabolic process	biological process	GO:0010906	101	2	18204	50	RORA,SORBS1
3.142e-02	-3.46	regulation of carbohydrate biosynthetic process	biological process	GO:0043255	101	2	18204	50	PRKG1,SORBS1
3.147e-02	-3.46	BIN1 (bridging integrator 1)	protein interactions	274	108	2	19454	50	CLU,GPM6A
3.147e-02	-3.46	FKBP1A (FKBP prolyl isomerase 1A)	protein interactions	2280	108	2	19454	50	RYR3,ERBB4
3.147e-02	-3.46	ALDH3B1 (aldehyde dehydrogenase 3 family member B1)	protein interactions	221	108	2	19454	50	FMN2,GFAP
3.152e-02	-3.46	Endothelins	Pathway Interaction DB	endothelinpathway	53	2	2226	12	PLCB1,ADCY2
3.152e-02	-3.46	PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling	REACTOME pathways	R-HSA-6811558	87	2	10285	33	NRG3,ERBB4
3.164e-02	-3.45	Activation of the AP-1 family of transcription factors	REACTOME pathways	R-HSA-450341	10	1	10285	33	MAPK10
3.164e-02	-3.45	Acetylcholine regulates insulin secretion	REACTOME pathways	R-HSA-399997	10	1	10285	33	PLCB1
3.164e-02	-3.45	Adenylate cyclase activating pathway	REACTOME pathways	R-HSA-170660	10	1	10285	33	ADCY2
3.167e-02	-3.45	VHP	smart domains	SM00153	8	1	9717	39	ABLIM1
3.175e-02	-3.45	Transmission across Chemical Synapses	REACTOME pathways	R-HSA-112315	217	3	10285	33	ADCY2,PLCB1,SLC1A2
3.180e-02	-3.45	FN3	prosite domains	PS50853	192	3	12186	44	PTPRZ1,CNTN1,TNC
3.190e-02	-3.45	CarboxypepD_reg	pfam domains	PF13620	12	1	17795	48	CPE
3.190e-02	-3.45	EF-hand_like	pfam domains	PF09279	12	1	17795	48	PLCB1
3.190e-02	-3.45	MH1	pfam domains	PF03165	12	1	17795	48	NFIA
3.193e-02	-3.44	MAD_homology1_Dwarfin-type	interpro domains	IPR003619	12	1	18521	50	NFIA
3.193e-02	-3.44	PLC_EF-hand-like	interpro domains	IPR015359	12	1	18521	50	PLCB1
3.193e-02	-3.44	MAP_kinase_CS	interpro domains	IPR003527	12	1	18521	50	MAPK10
3.199e-02	-3.44	sterol homeostasis	biological process	GO:0055092	102	2	18204	50	RORA,APOE
3.200e-02	-3.44	PRR20A (proline rich 20A)	protein interactions	122183	109	2	19454	50	TRPM3,SOX5
3.200e-02	-3.44	SIPA1L3 (signal induced proliferation associated 1 like 3)	protein interactions	23094	109	2	19454	50	PARD3,GFAP
3.204e-02	-3.44	human chr9q21.33	chromosome location	human chr9q21.33	17	1	26134	50	NTRK2
3.219e-02	-3.44	Cell junction organization	REACTOME pathways	R-HSA-446728	88	2	10285	33	CADM2,PARD3
3.240e-02	-3.43	EF-hand-dom_pair	interpro domains	IPR011992	258	3	18521	50	RYR3,PLCB1,DTNA
3.246e-02	-3.43	urinary_tract-bladder-carcinoma	COSMIC cancer mutations	urinary_tract-bladder-carcinoma	14050	45	16828	48	NRXN1,SLC1A2,NFIA,MAGI2,CPE,PPP2R2B,CDH20,RYR3,PCDH9,NRG3,MGAT4C,SORBS1,NEBL,CNTN1,ABLIM1,FUT9,HPSE2,DTNA,CTNND2,CLU,GPM6A,LRP1B,TNC,LSAMP,ANK2,TNIK,GFAP,RGS6,RORA,PARD3,ADCY2,NPAS3,GLIS3,NTRK2,PRKG1,PLCB1,PTPRZ1,SOX5,NTM,PITPNC1,CADM2,TRPM3,FMN2,ERBB4,GPC5
3.248e-02	-3.43	auditory behavior	biological process	GO:0031223	12	1	18204	50	NRXN1
3.248e-02	-3.43	response to interleukin-12	biological process	GO:0070671	12	1	18204	50	PLCB1
3.248e-02	-3.43	response to interleukin-15	biological process	GO:0070672	12	1	18204	50	PLCB1
3.248e-02	-3.43	negative regulation of smooth muscle contraction	biological process	GO:0045986	12	1	18204	50	PRKG1
3.248e-02	-3.43	sulfur amino acid transport	biological process	GO:0000101	12	1	18204	50	SLC1A2
3.248e-02	-3.43	neurotransmitter-gated ion channel clustering	biological process	GO:0072578	12	1	18204	50	APOE
3.249e-02	-3.43	Excitatory Neural Signalling Through 5-HTR 4 and Serotonin	SMPDB pathways	SMP0000309	9	1	1369	5	ADCY2
3.249e-02	-3.43	Intracellular Signalling Through Histamine H2 Receptor and Histamine	SMPDB pathways	SMP0000335	9	1	1369	5	ADCY2
3.249e-02	-3.43	Lysophosphatidic Acid LPA2 Signalling	SMPDB pathways	SMP0063753	9	1	1369	5	PLCB1
3.249e-02	-3.43	Intracellular Signalling Through FSH Receptor and Follicle Stimulating Hormone	SMPDB pathways	SMP0000333	9	1	1369	5	ADCY2
3.249e-02	-3.43	Excitatory Neural Signalling Through 5-HTR 7 and Serotonin	SMPDB pathways	SMP0000311	9	1	1369	5	ADCY2
3.249e-02	-3.43	Excitatory Neural Signalling Through 5-HTR 6 and Serotonin	SMPDB pathways	SMP0000312	9	1	1369	5	ADCY2
3.249e-02	-3.43	Lysophosphatidic Acid LPA1 Signalling	SMPDB pathways	SMP0063746	9	1	1369	5	PLCB1
3.271e-02	-3.42	RDX (radixin)	protein interactions	5962	272	3	19454	50	NEBL,ABLIM1,MAPK10
3.278e-02	-3.42	LIM	smart domains	SM00132	71	2	9717	39	ABLIM1,NEBL
3.291e-02	-3.41	MYO16 (myosin XVI)	protein interactions	23026	13	1	19454	50	NRXN1
3.291e-02	-3.41	RAB3C (RAB3C, member RAS oncogene family)	protein interactions	115827	13	1	19454	50	GPM6A
3.291e-02	-3.41	NCAN (neurocan)	protein interactions	1463	13	1	19454	50	TNC
3.291e-02	-3.41	JAM2 (junctional adhesion molecule 2)	protein interactions	58494	13	1	19454	50	PARD3
3.291e-02	-3.41	RNASE4 (ribonuclease A family member 4)	protein interactions	6038	13	1	19454	50	LRP1B
3.291e-02	-3.41	ANKH (ANKH inorganic pyrophosphate transport regulator)	protein interactions	56172	13	1	19454	50	APOE
3.291e-02	-3.41	TBCC (tubulin folding cofactor C)	protein interactions	6903	13	1	19454	50	NTM
3.291e-02	-3.41	PCDHA2 (protocadherin alpha 2)	protein interactions	56146	13	1	19454	50	NFIA
3.296e-02	-3.41	Carboxypeptidase-like, regulatory domain	gene3d domains	2.60.40.1120	11	1	14470	44	CPE
3.302e-02	-3.41	FLOT2 (flotillin 2)	protein interactions	2319	273	3	19454	50	PARD3,SOX5,NTRK2
3.318e-02	-3.41	protein complex oligomerization	biological process	GO:0051259	256	3	18204	50	RYR3,SLC1A2,TRPM3
3.332e-02	-3.40	phosphatidylinositol bisphosphate binding	molecular function	GO:1902936	108	2	18094	48	PARD3,PLCB1
3.350e-02	-3.40	chylomicron	cellular component	GO:0042627	13	1	19108	50	APOE
3.350e-02	-3.40	cytoplasmic side of lysosomal membrane	cellular component	GO:0098574	13	1	19108	50	GFAP
3.350e-02	-3.40	postsynaptic cytosol	cellular component	GO:0099524	13	1	19108	50	PLCB1
3.351e-02	-3.40	cell fate commitment	biological process	GO:0045165	257	3	18204	50	NFIA,ERBB4,SOX5
3.355e-02	-3.39	PI3K/AKT Signaling in Cancer	REACTOME pathways	R-HSA-2219528	90	2	10285	33	ERBB4,NRG3
3.363e-02	-3.39	TBR1 (T-box brain transcription factor 1)	protein interactions	10716	112	2	19454	50	NFIA,SOX5
3.363e-02	-3.39	HMGCS1 (3-hydroxy-3-methylglutaryl-CoA synthase 1)	protein interactions	3157	112	2	19454	50	GPM6A,PPP2R2B
3.363e-02	-3.39	EDA (ectodysplasin A)	protein interactions	1896	112	2	19454	50	ERBB4,GPM6A
3.363e-02	-3.39	TSC22D4 (TSC22 domain family member 4)	protein interactions	81628	112	2	19454	50	CLU,ABLIM1
3.373e-02	-3.39	response to interleukin-1	biological process	GO:0070555	105	2	18204	50	RORA,PLCB1
3.373e-02	-3.39	gland morphogenesis	biological process	GO:0022612	105	2	18204	50	NRG3,TNC
3.373e-02	-3.39	cellular response to alcohol	biological process	GO:0097306	105	2	18204	50	ADCY2,TNC
3.381e-02	-3.39	positive regulation of developmental process	biological process	GO:0051094	1385	8	18204	50	NRXN1,SOX5,ERBB4,GFAP,APOE,PLCB1,NTRK2,PTPRZ1
3.383e-02	-3.39	chromophobe_renal_cell_carcinoma	COSMIC cancer mutations	chromophobe_renal_cell_carcinoma	430	4	16828	48	PRKG1,NTRK2,TNIK,ERBB4
3.383e-02	-3.39	kidney-carcinoma-chromophobe_renal_cell_carcinoma	COSMIC cancer mutations	kidney-carcinoma-chromophobe_renal_cell_carcinoma	430	4	16828	48	ERBB4,TNIK,NTRK2,PRKG1
3.389e-02	-3.38	human chr7q31.32	chromosome location	human chr7q31.32	18	1	26134	50	PTPRZ1
3.389e-02	-3.38	human chr7q21.11	chromosome location	human chr7q21.11	18	1	26134	50	MAGI2
3.389e-02	-3.38	human chr18q21.33	chromosome location	human chr18q21.33	18	1	26134	50	CDH20
3.395e-02	-3.38	fucosyltransferase activity	molecular function	GO:0008417	13	1	18094	48	FUT9
3.398e-02	-3.38	central_nervous_system-brain-glioma-oligodendroglioma_Grade_III	COSMIC cancer mutations	central_nervous_system-brain-glioma-oligodendroglioma_Grade_III	249	3	16828	48	PTPRZ1,MGAT4C,GLIS3
3.400e-02	-3.38	calcium ion binding	molecular function	GO:0005509	683	5	18094	48	RYR3,NRXN1,PLCB1,LRP1B,PCDH9
3.405e-02	-3.38	NR3C1 (nuclear receptor subfamily 3 group C member 1)	protein interactions	2908	950	6	19454	50	PPP2R2B,NFIA,PLCB1,TNC,ADCY2,CTNND2
3.415e-02	-3.38	NGF signalling via TRKA from the plasma membrane	REACTOME pathways	R-HSA-187037	387	4	10285	33	ADCY2,NRG3,ERBB4,NTRK2
3.425e-02	-3.37	ZDHHC17 (zinc finger DHHC-type palmitoyltransferase 17)	protein interactions	23390	277	3	19454	50	GPM6A,NEBL,FUT9
3.432e-02	-3.37	cellular response to ketone	biological process	GO:1901655	106	2	18204	50	TNC,ADCY2
3.439e-02	-3.37	Human Thyroid Stimulating Hormone (TSH) signaling pathway	WikiPathways	WP2032	68	2	5310	23	PLCB1,ADCY2
3.452e-02	-3.37	Ldl_recept_b	pfam domains	PF00058	13	1	17795	48	LRP1B
3.454e-02	-3.37	ZU5_dom	interpro domains	IPR000906	13	1	18521	50	ANK2
3.455e-02	-3.37	distal axon	cellular component	GO:0150034	273	3	19108	50	PCDH9,GPM6A,NTRK2
3.455e-02	-3.37	phosphotransferase activity, alcohol group as acceptor	molecular function	GO:0016773	686	5	18094	48	PRKG1,MAPK10,ERBB4,TNIK,NTRK2
3.457e-02	-3.36	TJP2 (tight junction protein 2)	protein interactions	9414	278	3	19454	50	NEBL,PARD3,SORBS1
3.484e-02	-3.36	cell-cell adhesion via plasma-membrane adhesion molecules	biological process	GO:0098742	261	3	18204	50	CADM2,CDH20,PCDH9
3.492e-02	-3.35	Post-translational modification: synthesis of GPI-anchored proteins	REACTOME pathways	R-HSA-163125	92	2	10285	33	NTM,LSAMP
3.493e-02	-3.35	Ion_trans	pfam domains	PF00520	109	2	17795	48	RYR3,TRPM3
3.500e-02	-3.35	Ion_trans_dom	interpro domains	IPR005821	109	2	18521	50	TRPM3,RYR3
3.500e-02	-3.35	Cadherin_CS	interpro domains	IPR020894	109	2	18521	50	CDH20,PCDH9
3.514e-02	-3.35	glial cell fate commitment	biological process	GO:0021781	13	1	18204	50	NFIA
3.514e-02	-3.35	prepulse inhibition	biological process	GO:0060134	13	1	18204	50	CTNNA2
3.514e-02	-3.35	phospholipid efflux	biological process	GO:0033700	13	1	18204	50	APOE
3.514e-02	-3.35	cellular response to vitamin D	biological process	GO:0071305	13	1	18204	50	TNC
3.514e-02	-3.35	cerebellar Purkinje cell differentiation	biological process	GO:0021702	13	1	18204	50	RORA
3.514e-02	-3.35	regulation of dendritic spine maintenance	biological process	GO:1902950	13	1	18204	50	APOE
3.514e-02	-3.35	postsynaptic specialization assembly	biological process	GO:0098698	13	1	18204	50	NRXN1
3.514e-02	-3.35	ectodermal placode development	biological process	GO:0071696	13	1	18204	50	NRG3
3.514e-02	-3.35	T-helper 17 cell differentiation	biological process	GO:0072539	13	1	18204	50	RORA
3.514e-02	-3.35	negative regulation of homotypic cell-cell adhesion	biological process	GO:0034111	13	1	18204	50	PRKG1
3.514e-02	-3.35	defense response to tumor cell	biological process	GO:0002357	13	1	18204	50	RBMS3
3.514e-02	-3.35	olfactory bulb interneuron differentiation	biological process	GO:0021889	13	1	18204	50	ERBB4
3.527e-02	-3.34	ACTB (actin beta)	protein interactions	60	958	6	19454	50	FMN2,ABLIM1,APOE,NEBL,DTNA,SORBS1
3.528e-02	-3.34	soft_tissue-striated_muscle-rhabdomyosarcoma-alveolar	COSMIC cancer mutations	soft_tissue-striated_muscle-rhabdomyosarcoma-alveolar	2414	12	16828	48	RYR3,CDH20,PPP2R2B,TRPM3,FMN2,APOE,SORBS1,LRP1B,CLU,NFIA,NPAS3,PARD3
3.528e-02	-3.34	alveolar	COSMIC cancer mutations	alveolar	2414	12	16828	48	CLU,RYR3,NFIA,CDH20,NPAS3,FMN2,PPP2R2B,TRPM3,PARD3,LRP1B,APOE,SORBS1
3.530e-02	-3.34	DTNA (dystrobrevin alpha)	protein interactions	1837	115	2	19454	50	NTRK2,PARD3
3.530e-02	-3.34	SMAD7 (SMAD family member 7)	protein interactions	4092	115	2	19454	50	SOX5,PARD3
3.530e-02	-3.34	CDH2 (cadherin 2)	protein interactions	1000	115	2	19454	50	PARD3,CTNND2
3.539e-02	-3.34	HRAS (HRas proto-oncogene, GTPase)	protein interactions	3265	712	5	19454	50	PLCB1,PARD3,MAPK10,TNIK,PCDH9
3.540e-02	-3.34	SLC1A2 (solute carrier family 1 member 2)	protein interactions	6506	14	1	19454	50	SLC1A2
3.540e-02	-3.34	Stag2 (STAG2 cohesin complex component)	protein interactions	20843	14	1	19454	50	CLU
3.540e-02	-3.34	Aifm1 (apoptosis-inducing factor, mitochondrion-associated 1)	protein interactions	26926	14	1	19454	50	CLU
3.540e-02	-3.34	JMJD7-PLA2G4B (JMJD7-PLA2G4B readthrough)	protein interactions	8681	14	1	19454	50	PPP2R2B
3.540e-02	-3.34	CABS1 (calcium binding protein, spermatid associated 1)	protein interactions	85438	14	1	19454	50	GFAP
3.540e-02	-3.34	RSPO1 (R-spondin 1)	protein interactions	284654	14	1	19454	50	LRP1B
3.540e-02	-3.34	IFNA8 (interferon alpha 8)	protein interactions	3445	14	1	19454	50	APOE
3.540e-02	-3.34	SYT5 (synaptotagmin 5)	protein interactions	6861	14	1	19454	50	NRXN1
3.540e-02	-3.34	FCGBP (Fc gamma binding protein)	protein interactions	8857	14	1	19454	50	PPP2R2B
3.540e-02	-3.34	SH3YL1 (SH3 and SYLF domain containing 1)	protein interactions	26751	14	1	19454	50	GFAP
3.540e-02	-3.34	GRID2 (glutamate ionotropic receptor delta type subunit 2)	protein interactions	2895	14	1	19454	50	MAGI2
3.540e-02	-3.34	SPRR2D (small proline rich protein 2D)	protein interactions	6703	14	1	19454	50	PPP2R2B
3.540e-02	-3.34	GAGE1 (G antigen 1)	protein interactions	2543	14	1	19454	50	PRKG1
3.540e-02	-3.34	BOD1L2 (biorientation of chromosomes in cell division 1 like 2)	protein interactions	284257	14	1	19454	50	FMN2
3.540e-02	-3.34	OTUD7A (OTU deubiquitinase 7A)	protein interactions	161725	14	1	19454	50	ANK2
3.540e-02	-3.34	Nedd4 (neural precursor cell expressed, developmentally down-regulated 4)	protein interactions	17999	14	1	19454	50	GLIS3
3.554e-02	-3.34	MIR	prosite domains	PS50919	10	1	12186	44	RYR3
3.556e-02	-3.34	ZU5	smart domains	SM00218	9	1	9717	39	ANK2
3.573e-02	-3.33	Thyroid hormone synthesis	KEGG pathways	ko04918	74	2	7161	29	ADCY2,PLCB1
3.573e-02	-3.33	Thyroid hormone synthesis	KEGG pathways	hsa04918	74	2	7161	29	PLCB1,ADCY2
3.574e-02	-3.33	human chr5p15.2	chromosome location	human chr5p15.2	19	1	26134	50	CTNND2
3.574e-02	-3.33	human chr11q25	chromosome location	human chr11q25	19	1	26134	50	NTM
3.586e-02	-3.33	FCGRT (Fc gamma receptor and transporter)	protein interactions	2217	116	2	19454	50	CLU,CNTN1
3.586e-02	-3.33	RBBP8 (RB binding protein 8, endonuclease)	protein interactions	5932	116	2	19454	50	CLU,CTNNA2
3.588e-02	-3.33	cGMP signaling	KEGG pathways	M00694	9	1	7161	29	PRKG1
3.588e-02	-3.33	cGMP signaling	KEGG pathways	hsa_M00694	9	1	7161	29	PRKG1
3.588e-02	-3.33	Heparan sulfate degradation	KEGG pathways	hsa_M00078	9	1	7161	29	HPSE2
3.588e-02	-3.33	Heparan sulfate degradation	KEGG pathways	M00078	9	1	7161	29	HPSE2
3.590e-02	-3.33	Alpha-catenin/vinculin-like	gene3d domains	1.20.120.230	12	1	14470	44	CTNNA2
3.592e-02	-3.33	regulation of MAPK cascade	biological process	GO:0043408	669	5	18204	50	PLCB1,APOE,NTRK2,TNIK,ERBB4
3.603e-02	-3.32	chromaffin granule	cellular component	GO:0042583	14	1	19108	50	CLU
3.605e-02	-3.32	Lysophosphatidic Acid LPA4 Signalling	SMPDB pathways	SMP0063756	10	1	1369	5	PLCB1
3.605e-02	-3.32	Intracellular Signalling Through LHCGR Receptor and Luteinizing Hormone/Choriogonadotropin	SMPDB pathways	SMP0000338	10	1	1369	5	ADCY2
3.605e-02	-3.32	Lysophosphatidic Acid LPA5 Signalling	SMPDB pathways	SMP0063757	10	1	1369	5	PLCB1
3.609e-02	-3.32	stomach-carcinoma	COSMIC cancer mutations	stomach-carcinoma	439	4	16828	48	NTRK2,PRKG1,ERBB4,TNIK
3.619e-02	-3.32	signaling adaptor activity	molecular function	GO:0035591	113	2	18094	48	MAGI2,SORBS1
3.623e-02	-3.32	regulation of cellular process	biological process	GO:0050794	11468	38	18204	50	TNIK,PLCB1,GPC5,CTNNA2,CPE,RGS6,CNTN1,SOX5,PTPRZ1,CLU,HPSE2,APOE,PITPNC1,NFIA,FUT9,GFAP,CTNND2,FMN2,DTNA,MAGI2,RORA,MAPK10,ERBB4,GLIS3,RYR3,TNC,PARD3,ANK2,NRG3,NTRK2,ADCY2,PRKG1,RBMS3,NRXN1,GPM6A,NPAS3,SORBS1,SLC1A2
3.632e-02	-3.32	Negative regulation of the PI3K/AKT network	REACTOME pathways	R-HSA-199418	94	2	10285	33	NRG3,ERBB4
3.635e-02	-3.31	Chemokine signaling pathway	KEGG pathways	ko04062	182	3	7161	29	ADCY2,PLCB1,PARD3
3.635e-02	-3.31	Chemokine signaling pathway	KEGG pathways	hsa04062	182	3	7161	29	PARD3,PLCB1,ADCY2
3.652e-02	-3.31	L-glutamate transmembrane transporter activity	molecular function	GO:0005313	14	1	18094	48	SLC1A2
3.662e-02	-3.31	Gastric acid secretion	KEGG pathways	ko04971	75	2	7161	29	PLCB1,ADCY2
3.662e-02	-3.31	Gastric acid secretion	KEGG pathways	hsa04971	75	2	7161	29	PLCB1,ADCY2
3.670e-02	-3.31	phosphatidylinositol binding	molecular function	GO:0035091	276	3	18094	48	PLCB1,PARD3,PITPNC1
3.670e-02	-3.30	Cadherin	pfam domains	PF00028	112	2	17795	48	PCDH9,CDH20
3.672e-02	-3.30	positive regulation of cell junction assembly	biological process	GO:1901890	110	2	18204	50	NTRK2,NRXN1
3.682e-02	-3.30	postsynaptic membrane	cellular component	GO:0045211	280	3	19108	50	ANK2,ERBB4,CNTN1
3.699e-02	-3.30	SIPA1L2 (signal induced proliferation associated 1 like 2)	protein interactions	57568	118	2	19454	50	GFAP,PARD3
3.704e-02	-3.30	blood microparticle	cellular component	GO:0072562	116	2	19108	50	APOE,CLU
3.709e-02	-3.29	EGF	smart domains	SM00181	184	3	9717	39	LRP1B,TNC,NRXN1
3.715e-02	-3.29	LDLR_classB_rpt	interpro domains	IPR000033	14	1	18521	50	LRP1B
3.717e-02	-3.29	regulation of phosphate metabolic process	biological process	GO:0019220	1154	7	18204	50	APOE,NTRK2,TNIK,MAGI2,PARD3,PRKG1,ERBB4
3.724e-02	-3.29	regulation of signal transduction	biological process	GO:0009966	3114	14	18204	50	SORBS1,NRXN1,CTNND2,RBMS3,CLU,NTRK2,APOE,ERBB4,RGS6,MAGI2,TNIK,RORA,GPC5,PLCB1
3.732e-02	-3.29	regulation of phosphorus metabolic process	biological process	GO:0051174	1155	7	18204	50	ERBB4,PRKG1,NTRK2,APOE,PARD3,TNIK,MAGI2
3.735e-02	-3.29	urinary_tract	COSMIC cancer mutations	urinary_tract	14112	45	16828	48	DTNA,CTNND2,CLU,RGS6,GFAP,RORA,TNC,LRP1B,GPM6A,TNIK,ANK2,LSAMP,PRKG1,NTRK2,GLIS3,SOX5,NTM,PTPRZ1,PLCB1,PARD3,NPAS3,ADCY2,GPC5,CADM2,PITPNC1,ERBB4,FMN2,TRPM3,NFIA,NRXN1,SLC1A2,RYR3,CDH20,CPE,MAGI2,PPP2R2B,NRG3,MGAT4C,PCDH9,FUT9,HPSE2,NEBL,SORBS1,ABLIM1,CNTN1
3.735e-02	-3.29	bladder	COSMIC cancer mutations	bladder	14112	45	16828	48	FMN2,TRPM3,ABLIM1,CNTN1,ERBB4,NEBL,SORBS1,PITPNC1,CADM2,FUT9,HPSE2,GPC5,NPAS3,ADCY2,PCDH9,PARD3,PLCB1,MGAT4C,NTM,SOX5,PTPRZ1,GLIS3,NRG3,PRKG1,NTRK2,LSAMP,PPP2R2B,TNIK,ANK2,LRP1B,GPM6A,MAGI2,TNC,CPE,RORA,RYR3,RGS6,CDH20,GFAP,SLC1A2,NRXN1,CTNND2,CLU,NFIA,DTNA
3.756e-02	-3.28	ANKRD26 (ankyrin repeat domain containing 26)	protein interactions	22852	119	2	19454	50	PARD3,NTRK2
3.759e-02	-3.28	human chr8p21.1	chromosome location	human chr8p21.1	20	1	26134	50	CLU
3.762e-02	-3.28	phosphate-containing compound metabolic process	biological process	GO:0006796	1681	9	18204	50	ERBB4,PRKG1,PTPRZ1,TNIK,NTRK2,MAPK10,ADCY2,RORA,PLCB1
3.779e-02	-3.28	negative regulation of long-term synaptic potentiation	biological process	GO:1900272	14	1	18204	50	APOE
3.779e-02	-3.28	neurotransmitter receptor localization to postsynaptic specialization membrane	biological process	GO:0099645	14	1	18204	50	ERBB4
3.779e-02	-3.28	positive regulation of phospholipid transport	biological process	GO:2001140	14	1	18204	50	APOE
3.779e-02	-3.28	cellular response to purine-containing compound	biological process	GO:0071415	14	1	18204	50	RYR3
3.779e-02	-3.28	cellular response to forskolin	biological process	GO:1904322	14	1	18204	50	ADCY2
3.779e-02	-3.28	response to forskolin	biological process	GO:1904321	14	1	18204	50	ADCY2
3.779e-02	-3.28	glutathione biosynthetic process	biological process	GO:0006750	14	1	18204	50	SLC1A2
3.779e-02	-3.28	nerve growth factor signaling pathway	biological process	GO:0038180	14	1	18204	50	MAGI2
3.779e-02	-3.28	atrial cardiac muscle cell to AV node cell signaling	biological process	GO:0086026	14	1	18204	50	ANK2
3.779e-02	-3.28	mechanosensory behavior	biological process	GO:0007638	14	1	18204	50	NRXN1
3.779e-02	-3.28	atrial cardiac muscle cell action potential	biological process	GO:0086014	14	1	18204	50	ANK2
3.779e-02	-3.28	protein localization to postsynaptic specialization membrane	biological process	GO:0099633	14	1	18204	50	ERBB4
3.785e-02	-3.27	Defective EXT1 causes exostoses 1, TRPS2 and CHDS	REACTOME pathways	R-HSA-3656253	12	1	10285	33	GPC5
3.785e-02	-3.27	Defective EXT2 causes exostoses 2	REACTOME pathways	R-HSA-3656237	12	1	10285	33	GPC5
3.788e-02	-3.27	NPR1 (natriuretic peptide receptor 1)	protein interactions	4881	15	1	19454	50	PRKG1
3.788e-02	-3.27	PCSK1N (proprotein convertase subtilisin/kexin type 1 inhibitor)	protein interactions	27344	15	1	19454	50	MGAT4C
3.788e-02	-3.27	XIRP1 (xin actin binding repeat containing 1)	protein interactions	165904	15	1	19454	50	NEBL
3.788e-02	-3.27	OLFM3 (olfactomedin 3)	protein interactions	118427	15	1	19454	50	LRP1B
3.788e-02	-3.27	TAFA5 (TAFA chemokine like family member 5)	protein interactions	25817	15	1	19454	50	NEBL
3.788e-02	-3.27	DEFB123 (defensin beta 123)	protein interactions	245936	15	1	19454	50	LRP1B
3.794e-02	-3.27	regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction	biological process	GO:0051896	270	3	18204	50	MAGI2,ERBB4,NTRK2
3.794e-02	-3.27	rhythmic process	biological process	GO:0048511	270	3	18204	50	MAPK10,NTRK2,RORA
3.794e-02	-3.27	regulation of gliogenesis	biological process	GO:0014013	112	2	18204	50	GFAP,PTPRZ1
3.798e-02	-3.27	Cadherin-like_dom	interpro domains	IPR002126	114	2	18521	50	CDH20,PCDH9
3.810e-02	-3.27	CEP128 (centrosomal protein 128)	protein interactions	145508	289	3	19454	50	NEBL,ABLIM1,SORBS1
3.834e-02	-3.26	EV release from cardiac cells and their functional effects	WikiPathways	WP3297	9	1	5310	23	ERBB4
3.850e-02	-3.26	renal_cell_carcinoma	COSMIC cancer mutations	renal_cell_carcinoma	4535	19	16828	48	PTPRZ1,SOX5,CLU,CTNND2,PLCB1,NTRK2,PRKG1,PCDH9,NRXN1,RORA,RGS6,ANK2,ERBB4,CNTN1,TNIK,PPP2R2B,CADM2,PITPNC1,LRP1B
3.850e-02	-3.26	kidney-carcinoma-renal_cell_carcinoma	COSMIC cancer mutations	kidney-carcinoma-renal_cell_carcinoma	4535	19	16828	48	PCDH9,NRXN1,PTPRZ1,SOX5,CTNND2,CLU,PLCB1,NTRK2,PRKG1,CNTN1,ANK2,ERBB4,TNIK,PPP2R2B,CADM2,PITPNC1,LRP1B,RORA,RGS6
3.855e-02	-3.26	low-density lipoprotein particle	cellular component	GO:0034362	15	1	19108	50	APOE
3.855e-02	-3.26	axolemma	cellular component	GO:0030673	15	1	19108	50	SLC1A2
3.883e-02	-3.25	-	gene3d domains	2.60.220.30	13	1	14470	44	ANK2
3.884e-02	-3.25	lung-carcinoma-adenocarcinoma	COSMIC cancer mutations	lung-carcinoma-adenocarcinoma	15133	47	16828	48	LSAMP,TNIK,ANK2,LRP1B,GPM6A,TNC,RORA,RGS6,GFAP,NKAIN3,CLU,CTNND2,DTNA,FMN2,TRPM3,ERBB4,PITPNC1,CADM2,GPC5,NPAS3,ADCY2,PARD3,PLCB1,SOX5,NTM,PTPRZ1,GLIS3,PRKG1,NTRK2,PPP2R2B,MAGI2,APOE,CPE,RYR3,CDH20,SLC1A2,NRXN1,NFIA,ABLIM1,CNTN1,NEBL,SORBS1,FUT9,HPSE2,PCDH9,MGAT4C,NRG3
3.898e-02	-3.24	oligoastrocytoma_Grade_III	COSMIC cancer mutations	oligoastrocytoma_Grade_III	263	3	16828	48	RYR3,SOX5,SLC1A2
3.900e-02	-3.24	vascular process in circulatory system	biological process	GO:0003018	273	3	18204	50	SLC1A2,APOE,PRKG1
3.902e-02	-3.24	RECEPTOR_TYR_KIN_II	prosite domains	PS00239	11	1	12186	44	NTRK2
3.908e-02	-3.24	phosphatidylglycerol binding	molecular function	GO:1901611	15	1	18094	48	PITPNC1
3.908e-02	-3.24	neurexin family protein binding	molecular function	GO:0042043	15	1	18094	48	CPE
3.908e-02	-3.24	tropomyosin binding	molecular function	GO:0005523	15	1	18094	48	NEBL
3.908e-02	-3.24	low-density lipoprotein particle receptor activity	molecular function	GO:0005041	15	1	18094	48	LRP1B
3.908e-02	-3.24	filamin binding	molecular function	GO:0031005	15	1	18094	48	NEBL
3.918e-02	-3.24	negative regulation of small molecule metabolic process	biological process	GO:0062014	114	2	18204	50	PRKG1,APOE
3.920e-02	-3.24	Cadherin-like_sf	interpro domains	IPR015919	116	2	18521	50	PCDH9,CDH20
3.930e-02	-3.24	CYB5R1 (cytochrome b5 reductase 1)	protein interactions	51706	122	2	19454	50	APOE,PPP2R2B
3.935e-02	-3.24	skin-acral-malignant_melanoma	COSMIC cancer mutations	skin-acral-malignant_melanoma	264	3	16828	48	FMN2,CDH20,PARD3
3.943e-02	-3.23	human chr4q32.3	chromosome location	human chr4q32.3	21	1	26134	50	CPE
3.943e-02	-3.23	human chr13q31.3	chromosome location	human chr13q31.3	21	1	26134	50	GPC5
3.943e-02	-3.23	human chr10q23.1	chromosome location	human chr10q23.1	21	1	26134	50	NRG3
3.944e-02	-3.23	MIR	smart domains	SM00472	10	1	9717	39	RYR3
3.959e-02	-3.23	NAD+ Signalling and Aging	SMPDB pathways	SMP0084271	11	1	1369	5	RORA
3.972e-02	-3.23	FH2	pfam domains	PF02181	15	1	17795	48	FMN2
3.972e-02	-3.23	PI-PLC-Y	pfam domains	PF00387	15	1	17795	48	PLCB1
3.972e-02	-3.23	CNH	pfam domains	PF00780	15	1	17795	48	TNIK
3.975e-02	-3.23	FH2_Formin_sf	interpro domains	IPR042201	15	1	18521	50	FMN2
3.975e-02	-3.23	PI-PLC_fam	interpro domains	IPR001192	15	1	18521	50	PLCB1
3.975e-02	-3.23	PLipase_C_Pinositol-sp_Y	interpro domains	IPR001711	15	1	18521	50	PLCB1
3.975e-02	-3.23	CNH_dom	interpro domains	IPR001180	15	1	18521	50	TNIK
3.975e-02	-3.23	FH2_Formin	interpro domains	IPR015425	15	1	18521	50	FMN2
3.977e-02	-3.22	KCNE3 (potassium voltage-gated channel subfamily E regulatory subunit 3)	protein interactions	10008	294	3	19454	50	PCDH9,TNIK,PLCB1
3.988e-02	-3.22	GNAQ (G protein subunit alpha q)	protein interactions	2776	123	2	19454	50	PLCB1,GPM6A
4.017e-02	-3.21	ovary-carcinoma-clear_cell_carcinoma	COSMIC cancer mutations	ovary-carcinoma-clear_cell_carcinoma	665	5	16828	48	LRP1B,NTRK2,PRKG1,ERBB4,TNIK
4.019e-02	-3.21	membrane raft	cellular component	GO:0045121	290	3	19108	50	SORBS1,ADCY2,SLC1A2
4.028e-02	-3.21	phospholipid binding	molecular function	GO:0005543	489	4	18094	48	PARD3,PITPNC1,APOE,PLCB1
4.035e-02	-3.21	CYP2C8 (cytochrome P450 family 2 subfamily C member 8)	protein interactions	1558	16	1	19454	50	APOE
4.035e-02	-3.21	SYT4 (synaptotagmin 4)	protein interactions	6860	16	1	19454	50	NRXN1
4.035e-02	-3.21	CNTNAP2 (contactin associated protein 2)	protein interactions	26047	16	1	19454	50	CPE
4.035e-02	-3.21	GALNT13 (polypeptide N-acetylgalactosaminyltransferase 13)	protein interactions	114805	16	1	19454	50	TNIK
4.035e-02	-3.21	IFFO2 (intermediate filament family orphan 2)	protein interactions	126917	16	1	19454	50	GFAP
4.035e-02	-3.21	CDH12 (cadherin 12)	protein interactions	1010	16	1	19454	50	CTNNA2
4.035e-02	-3.21	SYTL2 (synaptotagmin like 2)	protein interactions	54843	16	1	19454	50	NRXN1
4.035e-02	-3.21	GABRR1 (gamma-aminobutyric acid type A receptor subunit rho1)	protein interactions	2569	16	1	19454	50	PRKG1
4.035e-02	-3.21	SYT9 (synaptotagmin 9)	protein interactions	143425	16	1	19454	50	NRXN1
4.035e-02	-3.21	TMEM134 (transmembrane protein 134)	protein interactions	80194	16	1	19454	50	ERBB4
4.035e-02	-3.21	SAPCD1 (suppressor APC domain containing 1)	protein interactions	401251	16	1	19454	50	CTNNA2
4.035e-02	-3.21	ORM2 (orosomucoid 2)	protein interactions	5005	16	1	19454	50	PPP2R2B
4.043e-02	-3.21	lipoprotein catabolic process	biological process	GO:0042159	15	1	18204	50	APOE
4.043e-02	-3.21	protein homotrimerization	biological process	GO:0070207	15	1	18204	50	SLC1A2
4.043e-02	-3.21	neuroblast division	biological process	GO:0055057	15	1	18204	50	SOX5
4.043e-02	-3.21	regulation of inositol phosphate biosynthetic process	biological process	GO:0010919	15	1	18204	50	PRKG1
4.043e-02	-3.21	peripheral nervous system neuron differentiation	biological process	GO:0048934	15	1	18204	50	NTRK2
4.043e-02	-3.21	positive regulation of glycogen biosynthetic process	biological process	GO:0045725	15	1	18204	50	SORBS1
4.043e-02	-3.21	synapse maturation	biological process	GO:0060074	15	1	18204	50	NFIA
4.043e-02	-3.21	positive regulation of cholesterol metabolic process	biological process	GO:0090205	15	1	18204	50	APOE
4.043e-02	-3.21	regulation of phospholipid transport	biological process	GO:2001138	15	1	18204	50	APOE
4.043e-02	-3.21	atrial cardiac muscle cell to AV node cell communication	biological process	GO:0086066	15	1	18204	50	ANK2
4.043e-02	-3.21	response to caffeine	biological process	GO:0031000	15	1	18204	50	RYR3
4.043e-02	-3.21	collateral sprouting	biological process	GO:0048668	15	1	18204	50	PRKG1
4.043e-02	-3.21	peripheral nervous system neuron development	biological process	GO:0048935	15	1	18204	50	NTRK2
4.043e-02	-3.21	negative regulation of amino acid transport	biological process	GO:0051956	15	1	18204	50	PRKG1
4.043e-02	-3.21	cerebellar Purkinje cell layer formation	biological process	GO:0021694	15	1	18204	50	RORA
4.043e-02	-3.21	exit from mitosis	biological process	GO:0010458	15	1	18204	50	NFIA
4.047e-02	-3.21	PSME2 (proteasome activator subunit 2)	protein interactions	5721	124	2	19454	50	PARD3,PPP2R2B
4.059e-02	-3.20	ovary-carcinoma-mucinous_carcinoma	COSMIC cancer mutations	ovary-carcinoma-mucinous_carcinoma	456	4	16828	48	PRKG1,NTRK2,TNIK,ERBB4
4.061e-02	-3.20	stomach-carcinoma-adenocarcinoma	COSMIC cancer mutations	stomach-carcinoma-adenocarcinoma	15150	47	16828	48	PPP2R2B,LSAMP,ANK2,TNIK,APOE,GPM6A,MAGI2,LRP1B,CPE,TNC,RORA,GFAP,RGS6,RYR3,CDH20,SLC1A2,NRXN1,RBMS3,CLU,CTNND2,NFIA,DTNA,TRPM3,FMN2,CNTN1,ERBB4,ABLIM1,SORBS1,PITPNC1,NEBL,CADM2,HPSE2,FUT9,GPC5,ADCY2,NPAS3,PARD3,PCDH9,MGAT4C,PLCB1,PTPRZ1,NTM,SOX5,NRG3,GLIS3,NTRK2,PRKG1
4.069e-02	-3.20	LZTS2 (leucine zipper tumor suppressor 2)	protein interactions	84445	506	4	19454	50	PARD3,SORBS1,GFAP,NEBL
4.076e-02	-3.20	TyrKc	smart domains	SM00219	80	2	9717	39	ERBB4,NTRK2
4.077e-02	-3.20	lung-carcinoma-non_small_cell_carcinoma	COSMIC cancer mutations	lung-carcinoma-non_small_cell_carcinoma	5198	21	16828	48	NPAS3,ADCY2,PARD3,CTNND2,SOX5,CLU,PTPRZ1,PLCB1,PRKG1,NTRK2,TNIK,ABLIM1,CNTN1,ERBB4,LSAMP,PPP2R2B,CADM2,LRP1B,PITPNC1,RORA,RGS6
4.077e-02	-3.20	non_small_cell_carcinoma	COSMIC cancer mutations	non_small_cell_carcinoma	5198	21	16828	48	PPP2R2B,LSAMP,CNTN1,ERBB4,TNIK,ABLIM1,PITPNC1,LRP1B,CADM2,RORA,RGS6,ADCY2,NPAS3,PARD3,PLCB1,PTPRZ1,CTNND2,CLU,SOX5,NTRK2,PRKG1
4.079e-02	-3.20	TJP1 (tight junction protein 1)	protein interactions	7082	297	3	19454	50	NEBL,PARD3,DTNA
4.080e-02	-3.20	actin filament organization	biological process	GO:0007015	278	3	18204	50	FMN2,SORBS1,NEBL
4.080e-02	-3.20	regulation of GTPase activity	biological process	GO:0043087	278	3	18204	50	PRKG1,NTRK2,RGS6
4.085e-02	-3.20	acral	COSMIC cancer mutations	acral	268	3	16828	48	FMN2,PARD3,CDH20
4.088e-02	-3.20	membrane microdomain	cellular component	GO:0098857	292	3	19108	50	ADCY2,SLC1A2,SORBS1
4.092e-02	-3.20	phosphorus metabolic process	biological process	GO:0006793	1707	9	18204	50	ERBB4,PRKG1,PTPRZ1,TNIK,MAPK10,ADCY2,NTRK2,PLCB1,RORA
4.105e-02	-3.19	clear_cell_carcinoma	COSMIC cancer mutations	clear_cell_carcinoma	669	5	16828	48	LRP1B,NTRK2,PRKG1,ERBB4,TNIK
4.106e-02	-3.19	TCHP (trichoplein keratin filament binding)	protein interactions	84260	125	2	19454	50	GFAP,PARD3
4.106e-02	-3.19	SCGB1D1 (secretoglobin family 1D member 1)	protein interactions	10648	125	2	19454	50	CPE,LRP1B
4.107e-02	-3.19	regulation of synapse assembly	biological process	GO:0051963	117	2	18204	50	NRXN1,NTRK2
4.107e-02	-3.19	postsynaptic density, intracellular component	cellular component	GO:0099092	16	1	19108	50	TNIK
4.114e-02	-3.19	mucinous_carcinoma	COSMIC cancer mutations	mucinous_carcinoma	458	4	16828	48	NTRK2,PRKG1,ERBB4,TNIK
4.127e-02	-3.19	human chr3q13.31	chromosome location	human chr3q13.31	22	1	26134	50	LSAMP
4.128e-02	-3.19	EGF_2	prosite domains	PS01186	213	3	12186	44	NRG3,TNC,LRP1B
4.139e-02	-3.18	L1CAM interactions	REACTOME pathways	R-HSA-373760	101	2	10285	33	CNTN1,ANK2
4.139e-02	-3.18	Visual phototransduction	REACTOME pathways	R-HSA-2187338	101	2	10285	33	APOE,GPC5
4.163e-02	-3.18	misfolded protein binding	molecular function	GO:0051787	16	1	18094	48	CLU
4.163e-02	-3.18	adenylate cyclase activity	molecular function	GO:0004016	16	1	18094	48	ADCY2
4.163e-02	-3.18	MAP kinase activity	molecular function	GO:0004707	16	1	18094	48	MAPK10
4.163e-02	-3.18	lamin binding	molecular function	GO:0005521	16	1	18094	48	PLCB1
4.163e-02	-3.18	cGMP binding	molecular function	GO:0030553	16	1	18094	48	PRKG1
4.163e-02	-3.18	oxysterol binding	molecular function	GO:0008142	16	1	18094	48	RORA
4.163e-02	-3.18	MAP kinase kinase activity	molecular function	GO:0004708	16	1	18094	48	MAPK10
4.166e-02	-3.18	SYP (synaptophysin)	protein interactions	6855	126	2	19454	50	GPM6A,PITPNC1
4.166e-02	-3.18	SERPINA3 (serpin family A member 3)	protein interactions	12	126	2	19454	50	CLU,PPP2R2B
4.170e-02	-3.18	regulation of receptor-mediated endocytosis	biological process	GO:0048259	118	2	18204	50	CLU,MAGI2
4.176e-02	-3.18	-	gene3d domains	2.20.25.10	14	1	14470	44	TNC
4.226e-02	-3.16	DES (desmin)	protein interactions	1674	127	2	19454	50	GFAP,DTNA
4.235e-02	-3.16	cNMP-bd_CS	interpro domains	IPR018488	16	1	18521	50	PRKG1
4.235e-02	-3.16	CarboxyPept-like_regulatory	interpro domains	IPR008969	16	1	18521	50	CPE
4.235e-02	-3.16	Guanylate_kinase_CS	interpro domains	IPR020590	16	1	18521	50	MAGI2
4.250e-02	-3.16	MAPK	prosite domains	PS01351	12	1	12186	44	MAPK10
4.250e-02	-3.16	CNMP_BINDING_2	prosite domains	PS00889	12	1	12186	44	PRKG1
4.252e-02	-3.16	Composition of Lipid Particles	WikiPathways	WP3601	10	1	5310	23	APOE
4.282e-02	-3.15	ovary-carcinoma-endometrioid_carcinoma	COSMIC cancer mutations	ovary-carcinoma-endometrioid_carcinoma	464	4	16828	48	NTRK2,PRKG1,ERBB4,TNIK
4.282e-02	-3.15	SHD (Src homology 2 domain containing transforming protein D)	protein interactions	56961	17	1	19454	50	ERBB4
4.282e-02	-3.15	CLEC4M (C-type lectin domain family 4 member M)	protein interactions	10332	17	1	19454	50	GFAP
4.282e-02	-3.15	SEPSECS (Sep (O-phosphoserine) tRNA:Sec (selenocysteine) tRNA synthase)	protein interactions	51091	17	1	19454	50	ABLIM1
4.282e-02	-3.15	DPP6 (dipeptidyl peptidase like 6)	protein interactions	1804	17	1	19454	50	GPM6A
4.282e-02	-3.15	CNTN2 (contactin 2)	protein interactions	6900	17	1	19454	50	CNTN1
4.282e-02	-3.15	EPB42 (erythrocyte membrane protein band 4.2)	protein interactions	2038	17	1	19454	50	ANK2
4.282e-02	-3.15	C16orf92 (chromosome 16 open reading frame 92)	protein interactions	146378	17	1	19454	50	APOE
4.282e-02	-3.15	Shcbp1 (Shc SH2-domain binding protein 1)	protein interactions	20419	17	1	19454	50	GPC5
4.282e-02	-3.15	TAGAP (T cell activation RhoGTPase activating protein)	protein interactions	117289	17	1	19454	50	DTNA
4.282e-02	-3.15	PAX4 (paired box 4)	protein interactions	5078	17	1	19454	50	NTM
4.282e-02	-3.15	SCN1B (sodium voltage-gated channel beta subunit 1)	protein interactions	6324	17	1	19454	50	CNTN1
4.282e-02	-3.15	MSANTD2 (Myb/SANT DNA binding domain containing 2)	protein interactions	79684	17	1	19454	50	SOX5
4.285e-02	-3.15	PDZ	pfam domains	PF00595	122	2	17795	48	MAGI2,PARD3
4.286e-02	-3.15	FARP1 (FERM, ARH/RhoGEF and pleckstrin domain protein 1)	protein interactions	10160	128	2	19454	50	ANK2,PARD3
4.299e-02	-3.15	regulation of nervous system process	biological process	GO:0031644	120	2	18204	50	PARD3,NRXN1
4.302e-02	-3.15	bicellular tight junction	cellular component	GO:0005923	126	2	19108	50	MAGI2,PARD3
4.307e-02	-3.14	positive regulation of membrane protein ectodomain proteolysis	biological process	GO:0051044	16	1	18204	50	APOE
4.307e-02	-3.14	locomotory exploration behavior	biological process	GO:0035641	16	1	18204	50	APOE
4.307e-02	-3.14	fucose metabolic process	biological process	GO:0006004	16	1	18204	50	FUT9
4.307e-02	-3.14	neuron cell-cell adhesion	biological process	GO:0007158	16	1	18204	50	NRXN1
4.307e-02	-3.14	insulin metabolic process	biological process	GO:1901142	16	1	18204	50	CPE
4.307e-02	-3.14	response to ether	biological process	GO:0045472	16	1	18204	50	PLCB1
4.307e-02	-3.14	nonribosomal peptide biosynthetic process	biological process	GO:0019184	16	1	18204	50	SLC1A2
4.307e-02	-3.14	cardiac left ventricle morphogenesis	biological process	GO:0003214	16	1	18204	50	CPE
4.307e-02	-3.14	low-density lipoprotein particle remodeling	biological process	GO:0034374	16	1	18204	50	APOE
4.308e-02	-3.14	Aldosterone synthesis and secretion	KEGG pathways	hsa04925	82	2	7161	29	PLCB1,ADCY2
4.308e-02	-3.14	Aldosterone synthesis and secretion	KEGG pathways	ko04925	82	2	7161	29	PLCB1,ADCY2
4.311e-02	-3.14	human chr2q34	chromosome location	human chr2q34	23	1	26134	50	ERBB4
4.311e-02	-3.14	human chr5p15.31	chromosome location	human chr5p15.31	23	1	26134	50	ADCY2
4.312e-02	-3.14	positive regulation of molecular function	biological process	GO:0044093	1192	7	18204	50	ERBB4,ANK2,MAGI2,CLU,NTRK2,RGS6,APOE
4.358e-02	-3.13	apical dendrite	cellular component	GO:0097440	17	1	19108	50	CLU
4.358e-02	-3.13	protein complex involved in cell-matrix adhesion	cellular component	GO:0098637	17	1	19108	50	TNC
4.364e-02	-3.13	Stimuli-sensing channels	REACTOME pathways	R-HSA-2672351	104	2	10285	33	RYR3,TRPM3
4.379e-02	-3.13	pleura	COSMIC cancer mutations	pleura	4914	20	16828	48	RORA,RGS6,ERBB4,CNTN1,TNIK,PPP2R2B,FMN2,CADM2,MAGI2,PITPNC1,NEBL,LRP1B,PTPRZ1,CTNND2,SOX5,CLU,NTM,PLCB1,NTRK2,PRKG1
4.402e-02	-3.12	DCC mediated attractive signaling	REACTOME pathways	R-HSA-418885	14	1	10285	33	ABLIM1
4.417e-02	-3.12	transmembrane receptor protein tyrosine phosphatase activity	molecular function	GO:0005001	17	1	18094	48	PTPRZ1
4.417e-02	-3.12	transmembrane receptor protein phosphatase activity	molecular function	GO:0019198	17	1	18094	48	PTPRZ1
4.426e-02	-3.12	neuron projection terminus	cellular component	GO:0044306	128	2	19108	50	SLC1A2,NTRK2
4.434e-02	-3.12	enzyme binding	molecular function	GO:0019899	2086	10	18094	48	CLU,PRKG1,ANK2,APOE,PLCB1,GFAP,MAGI2,NRG3,NTRK2,ADCY2
4.467e-02	-3.11	Formin, FH2 domain	gene3d domains	1.20.58.2220	15	1	14470	44	FMN2
4.468e-02	-3.11	TRPS1 (transcriptional repressor GATA binding 1)	protein interactions	7227	131	2	19454	50	NFIA,SOX5
4.468e-02	-3.11	ZNF609 (zinc finger protein 609)	protein interactions	23060	131	2	19454	50	SOX5,NFIA
4.468e-02	-3.11	NCOA2 (nuclear receptor coactivator 2)	protein interactions	10499	131	2	19454	50	RORA,NFIA
4.490e-02	-3.10	PI-PLC-X	pfam domains	PF00388	17	1	17795	48	PLCB1
4.490e-02	-3.10	ZZ	pfam domains	PF00569	17	1	17795	48	DTNA
4.490e-02	-3.10	G-gamma	pfam domains	PF00631	17	1	17795	48	RGS6
4.490e-02	-3.10	Carb_anhydrase	pfam domains	PF00194	17	1	17795	48	PTPRZ1
4.493e-02	-3.10	GGL_sf	interpro domains	IPR036284	17	1	18521	50	RGS6
4.493e-02	-3.10	CA_dom_sf	interpro domains	IPR036398	17	1	18521	50	PTPRZ1
4.493e-02	-3.10	PLipase_C_PInositol-sp_X_dom	interpro domains	IPR000909	17	1	18521	50	PLCB1
4.493e-02	-3.10	CA_dom	interpro domains	IPR001148	17	1	18521	50	PTPRZ1
4.493e-02	-3.10	G-protein_gamma-like_dom	interpro domains	IPR015898	17	1	18521	50	RGS6
4.493e-02	-3.10	A/G_cyclase_CS	interpro domains	IPR018297	17	1	18521	50	ADCY2
4.499e-02	-3.10	ITCH (itchy E3 ubiquitin protein ligase)	protein interactions	83737	309	3	19454	50	ERBB4,GLIS3,RORA
4.517e-02	-3.10	PROTEIN_KINASE_TYR	prosite domains	PS00109	94	2	12186	44	NTRK2,ERBB4
4.525e-02	-3.10	kinase activity	molecular function	GO:0016301	739	5	18094	48	NTRK2,MAPK10,PRKG1,ERBB4,TNIK
4.529e-02	-3.09	CYP2E1 (cytochrome P450 family 2 subfamily E member 1)	protein interactions	1571	18	1	19454	50	CLU
4.529e-02	-3.09	ACAP1 (ArfGAP with coiled-coil, ankyrin repeat and PH domains 1)	protein interactions	9744	18	1	19454	50	NEBL
4.529e-02	-3.09	OPCML (opioid binding protein/cell adhesion molecule like)	protein interactions	4978	18	1	19454	50	NTM
4.529e-02	-3.09	RHBDL1 (rhomboid like 1)	protein interactions	9028	18	1	19454	50	MAGI2
4.529e-02	-3.09	ZNF224 (zinc finger protein 224)	protein interactions	7767	18	1	19454	50	LRP1B
4.529e-02	-3.09	Lck (lymphocyte protein tyrosine kinase)	protein interactions	16818	18	1	19454	50	APOE
4.529e-02	-3.09	SERTAD4 (SERTA domain containing 4)	protein interactions	56256	18	1	19454	50	PPP2R2B
4.529e-02	-3.09	NECTIN1 (nectin cell adhesion molecule 1)	protein interactions	5818	18	1	19454	50	PARD3
4.529e-02	-3.09	SELL (selectin L)	protein interactions	6402	18	1	19454	50	PRKG1
4.553e-02	-3.09	skin-back-malignant_melanoma	COSMIC cancer mutations	skin-back-malignant_melanoma	280	3	16828	48	LRP1B,ERBB4,TNIK
4.560e-02	-3.09	action potential	biological process	GO:0001508	124	2	18204	50	ANK2,NTRK2
4.560e-02	-3.09	positive regulation of lipid metabolic process	biological process	GO:0045834	124	2	18204	50	SORBS1,APOE
4.560e-02	-3.09	cardiocyte differentiation	biological process	GO:0035051	124	2	18204	50	NEBL,PRKG1
4.570e-02	-3.09	regulation of fertilization	biological process	GO:0080154	17	1	18204	50	PLCB1
4.570e-02	-3.09	negative regulation of activin receptor signaling pathway	biological process	GO:0032926	17	1	18204	50	MAGI2
4.570e-02	-3.09	positive regulation of meiotic nuclear division	biological process	GO:0045836	17	1	18204	50	PLCB1
4.570e-02	-3.09	fatty acid homeostasis	biological process	GO:0055089	17	1	18204	50	APOE
4.570e-02	-3.09	high-density lipoprotein particle remodeling	biological process	GO:0034375	17	1	18204	50	APOE
4.570e-02	-3.09	membrane depolarization during cardiac muscle cell action potential	biological process	GO:0086012	17	1	18204	50	ANK2
4.570e-02	-3.09	microvillus assembly	biological process	GO:0030033	17	1	18204	50	TNIK
4.570e-02	-3.09	positive regulation of glycogen metabolic process	biological process	GO:0070875	17	1	18204	50	SORBS1
4.570e-02	-3.09	negative regulation of triglyceride metabolic process	biological process	GO:0090209	17	1	18204	50	APOE
4.570e-02	-3.09	protein trimerization	biological process	GO:0070206	17	1	18204	50	SLC1A2
4.570e-02	-3.09	cell migration in hindbrain	biological process	GO:0021535	17	1	18204	50	CTNNA2
4.570e-02	-3.09	retinal rod cell differentiation	biological process	GO:0060221	17	1	18204	50	NTRK2
4.570e-02	-3.09	ureter development	biological process	GO:0072189	17	1	18204	50	NFIA
4.570e-02	-3.09	mammary gland epithelial cell differentiation	biological process	GO:0060644	17	1	18204	50	ERBB4
4.570e-02	-3.09	regulation of inclusion body assembly	biological process	GO:0090083	17	1	18204	50	CLU
4.570e-02	-3.09	fucosylation	biological process	GO:0036065	17	1	18204	50	FUT9
4.570e-02	-3.09	T-helper 17 type immune response	biological process	GO:0072538	17	1	18204	50	RORA
4.570e-02	-3.09	positive regulation of vascular permeability	biological process	GO:0043117	17	1	18204	50	APOE
4.570e-02	-3.09	cellular response to ATP	biological process	GO:0071318	17	1	18204	50	RYR3
4.570e-02	-3.09	viral genome replication	biological process	GO:0019079	17	1	18204	50	NFIA
4.570e-02	-3.09	branch elongation of an epithelium	biological process	GO:0060602	17	1	18204	50	TNC
4.570e-02	-3.09	cGMP metabolic process	biological process	GO:0046068	17	1	18204	50	RORA
4.596e-02	-3.08	CARBOXYPEPT_ZN_1	prosite domains	PS00132	13	1	12186	44	CPE
4.596e-02	-3.08	CARBOXYPEPT_ZN_2	prosite domains	PS00133	13	1	12186	44	CPE
4.596e-02	-3.08	ZU5	prosite domains	PS51145	13	1	12186	44	ANK2
4.596e-02	-3.08	LDLRB	prosite domains	PS51120	13	1	12186	44	LRP1B
4.596e-02	-3.08	Insulin secretion	KEGG pathways	hsa04911	85	2	7161	29	PLCB1,ADCY2
4.598e-02	-3.08	haematopoietic_and_lymphoid_tissue-abdomen-lymphoid_neoplasm-diffuse_large_B_cell_lymphoma	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue-abdomen-lymphoid_neoplasm-diffuse_large_B_cell_lymphoma	120	2	16828	48	FMN2,CTNND2
4.609e-02	-3.08	costamere	cellular component	GO:0043034	18	1	19108	50	ANK2
4.609e-02	-3.08	protein phosphatase type 2A complex	cellular component	GO:0000159	18	1	19108	50	PPP2R2B
4.614e-02	-3.08	tight junction	cellular component	GO:0070160	131	2	19108	50	MAGI2,PARD3
4.626e-02	-3.07	mammary gland development	biological process	GO:0030879	125	2	18204	50	NRG3,ERBB4
4.626e-02	-3.07	memory	biological process	GO:0007613	125	2	18204	50	APOE,PLCB1
4.626e-02	-3.07	actomyosin structure organization	biological process	GO:0031032	125	2	18204	50	SORBS1,NEBL
4.626e-02	-3.07	cerebral cortex development	biological process	GO:0021987	125	2	18204	50	PLCB1,NTRK2
4.629e-02	-3.07	parathyroid	COSMIC cancer mutations	parathyroid	476	4	16828	48	GPC5,GPM6A,RYR3,PRKG1
4.636e-02	-3.07	PROTEIN_KINASE_ATP	prosite domains	PS00107	377	4	12186	44	PRKG1,TNIK,ERBB4,NTRK2
4.653e-02	-3.07	EGFR (epidermal growth factor receptor)	protein interactions	1956	3105	13	19454	50	ANK2,TNC,SORBS1,CLU,TNIK,NTRK2,TRPM3,DTNA,PARD3,CTNNA2,CTNND2,ABLIM1,ERBB4
4.665e-02	-3.07	Succinate Signalling During Inflammation	SMPDB pathways	SMP0084634	13	1	1369	5	PLCB1
4.667e-02	-3.06	oligoastrocytoma_Grade_II	COSMIC cancer mutations	oligoastrocytoma_Grade_II	121	2	16828	48	DTNA,CDH20
4.671e-02	-3.06	transmembrane receptor protein tyrosine kinase activator activity	molecular function	GO:0030297	18	1	18094	48	NRG3
4.671e-02	-3.06	phosphatidylcholine transporter activity	molecular function	GO:0008525	18	1	18094	48	PITPNC1
4.671e-02	-3.06	intracellularly gated calcium channel activity	molecular function	GO:0015278	18	1	18094	48	RYR3
4.671e-02	-3.06	acidic amino acid transmembrane transporter activity	molecular function	GO:0015172	18	1	18094	48	SLC1A2
4.671e-02	-3.06	GABA receptor binding	molecular function	GO:0050811	18	1	18094	48	ERBB4
4.671e-02	-3.06	lipoprotein particle receptor activity	molecular function	GO:0030228	18	1	18094	48	LRP1B
4.671e-02	-3.06	adrenergic receptor binding	molecular function	GO:0031690	18	1	18094	48	MAGI2
4.674e-02	-3.06	GRB2 (growth factor receptor bound protein 2)	protein interactions	2885	769	5	19454	50	CLU,NTRK2,GFAP,ERBB4,SLC1A2
4.677e-02	-3.06	human chr20p12.3	chromosome location	human chr20p12.3	25	1	26134	50	PLCB1
4.696e-02	-3.06	Cadherins	gene3d domains	2.60.40.60	114	2	14470	44	CDH20,PCDH9
4.709e-02	-3.06	Inhibition of adenylate cyclase pathway	REACTOME pathways	R-HSA-997269	15	1	10285	33	ADCY2
4.709e-02	-3.06	N-Glycan antennae elongation	REACTOME pathways	R-HSA-975577	15	1	10285	33	MGAT4C
4.709e-02	-3.06	Adenylate cyclase inhibitory pathway	REACTOME pathways	R-HSA-170670	15	1	10285	33	ADCY2
4.714e-02	-3.05	DWA	smart domains	SM00523	12	1	9717	39	NFIA
4.716e-02	-3.05	FOXP1 (forkhead box P1)	protein interactions	27086	135	2	19454	50	NFIA,SOX5
4.716e-02	-3.05	FAM83H (family with sequence similarity 83 member H)	protein interactions	286077	135	2	19454	50	PPP2R2B,GFAP
4.725e-02	-3.05	regulation of ERK1 and ERK2 cascade	biological process	GO:0070372	295	3	18204	50	ERBB4,APOE,NTRK2
4.725e-02	-3.05	regulation of endocytosis	biological process	GO:0030100	295	3	18204	50	CLU,MAGI2,APOE
4.746e-02	-3.05	Growth_fac_rcpt_cys_sf	interpro domains	IPR009030	129	2	18521	50	ERBB4,LRP1B
4.748e-02	-3.05	Guanylate_cyc	pfam domains	PF00211	18	1	17795	48	ADCY2
4.750e-02	-3.05	monoatomic ion transport	biological process	GO:0006811	964	6	18204	50	RYR3,ANK2,TRPM3,PLCB1,SLC1A2,GPM6A
4.752e-02	-3.05	Nucleotide_cyclase	interpro domains	IPR029787	18	1	18521	50	ADCY2
4.752e-02	-3.05	A/G_cyclase	interpro domains	IPR001054	18	1	18521	50	ADCY2
4.752e-02	-3.05	Furin_repeat	interpro domains	IPR006212	18	1	18521	50	ERBB4
4.760e-02	-3.05	response to amino acid	biological process	GO:0043200	127	2	18204	50	NTRK2,SLC1A2
4.760e-02	-3.05	negative regulation of neuron projection development	biological process	GO:0010977	127	2	18204	50	GFAP,APOE
4.774e-02	-3.04	Trp53 (transformation related protein 53)	protein interactions	22059	19	1	19454	50	MAPK10
4.774e-02	-3.04	ZNF532 (zinc finger protein 532)	protein interactions	55205	19	1	19454	50	ERBB4
4.774e-02	-3.04	NLGN1 (neuroligin 1)	protein interactions	22871	19	1	19454	50	NRXN1
4.774e-02	-3.04	RIT2 (Ras like without CAAX 2)	protein interactions	6014	19	1	19454	50	DTNA
4.774e-02	-3.04	GCHFR (GTP cyclohydrolase I feedback regulator)	protein interactions	2644	19	1	19454	50	NEBL
4.774e-02	-3.04	OSM (oncostatin M)	protein interactions	5008	19	1	19454	50	TRPM3
4.774e-02	-3.04	PDP2 (pyruvate dehydrogenase phosphatase catalytic subunit 2)	protein interactions	57546	19	1	19454	50	GFAP
4.774e-02	-3.04	PLA2G4E (phospholipase A2 group IVE)	protein interactions	123745	19	1	19454	50	PPP2R2B
4.774e-02	-3.04	EGFL6 (EGF like domain multiple 6)	protein interactions	25975	19	1	19454	50	LRP1B
4.774e-02	-3.04	PHYHIPL (phytanoyl-CoA 2-hydroxylase interacting protein like)	protein interactions	84457	19	1	19454	50	GPM6A
4.774e-02	-3.04	SPZ1 (spermatogenic leucine zipper 1)	protein interactions	84654	19	1	19454	50	DTNA
4.774e-02	-3.04	HBEGF (heparin binding EGF like growth factor)	protein interactions	1839	19	1	19454	50	ERBB4
4.774e-02	-3.04	SYT7 (synaptotagmin 7)	protein interactions	9066	19	1	19454	50	NRXN1
4.774e-02	-3.04	KCNF1 (potassium voltage-gated channel modifier subfamily F member 1)	protein interactions	3754	19	1	19454	50	GFAP
4.774e-02	-3.04	PLCB2 (phospholipase C beta 2)	protein interactions	5330	19	1	19454	50	PLCB1
4.774e-02	-3.04	ADRB1 (adrenoceptor beta 1)	protein interactions	153	19	1	19454	50	MAGI2
4.774e-02	-3.04	FBXO27 (F-box protein 27)	protein interactions	126433	19	1	19454	50	CLU
4.775e-02	-3.04	endocytosis	biological process	GO:0006897	499	4	18204	50	APOE,MAGI2,LRP1B,ANK2
4.776e-02	-3.04	Proteoglycans in cancer	KEGG pathways	hsa05205	203	3	7161	29	ERBB4,ANK2,HPSE2
4.776e-02	-3.04	Proteoglycans in cancer	KEGG pathways	ko05205	203	3	7161	29	ERBB4,HPSE2,ANK2
4.782e-02	-3.04	regulation of multicellular organismal development	biological process	GO:2000026	1484	8	18204	50	PARD3,PTPRZ1,NTRK2,PLCB1,ERBB4,GFAP,SOX5,NRXN1
4.802e-02	-3.04	ductal_carcinoma	COSMIC cancer mutations	ductal_carcinoma	15798	48	16828	48	FUT9,HPSE2,SORBS1,NEBL,CNTN1,ABLIM1,NRG3,MGAT4C,PCDH9,RYR3,CDH20,APOE,MAGI2,CPE,PPP2R2B,NFIA,RBMS3,NRXN1,SLC1A2,GPC5,PITPNC1,CADM2,TRPM3,FMN2,ERBB4,GLIS3,NTRK2,PRKG1,PLCB1,PTPRZ1,SOX5,NTM,PARD3,ADCY2,NPAS3,GFAP,RGS6,RORA,GPM6A,LRP1B,TNC,LSAMP,ANK2,TNIK,DTNA,CTNND2,CLU,NKAIN3
4.802e-02	-3.04	PK_Tyr_Ser-Thr	pfam domains	PF07714	130	2	17795	48	ERBB4,NTRK2
4.814e-02	-3.03	endoplasmic reticulum lumen	cellular component	GO:0005788	312	3	19108	50	APOE,CLU,TNC
4.832e-02	-3.03	regulation of leukocyte tethering or rolling	biological process	GO:1903236	18	1	18204	50	FUT9
4.832e-02	-3.03	cardiac myofibril assembly	biological process	GO:0055003	18	1	18204	50	NEBL
4.832e-02	-3.03	negative regulation of anoikis	biological process	GO:2000811	18	1	18204	50	NTRK2
4.832e-02	-3.03	myelin maintenance	biological process	GO:0043217	18	1	18204	50	CLU
4.832e-02	-3.03	positive regulation of myelination	biological process	GO:0031643	18	1	18204	50	PARD3
4.832e-02	-3.03	regulation of acrosome reaction	biological process	GO:0060046	18	1	18204	50	PLCB1
4.832e-02	-3.03	regulation of establishment of endothelial barrier	biological process	GO:1903140	18	1	18204	50	PLCB1
4.832e-02	-3.03	regulation of endothelial cell development	biological process	GO:1901550	18	1	18204	50	PLCB1
4.832e-02	-3.03	response to misfolded protein	biological process	GO:0051788	18	1	18204	50	CLU
4.832e-02	-3.03	dendritic spine morphogenesis	biological process	GO:0060997	18	1	18204	50	CTNND2
4.842e-02	-3.03	TBL1X (transducin beta like 1 X-linked)	protein interactions	6907	137	2	19454	50	SOX5,NFIA
4.859e-02	-3.02	cytosolic region	cellular component	GO:0099522	19	1	19108	50	PLCB1
4.859e-02	-3.02	parallel fiber to Purkinje cell synapse	cellular component	GO:0098688	19	1	19108	50	GPM6A
4.859e-02	-3.02	postsynaptic specialization, intracellular component	cellular component	GO:0099091	19	1	19108	50	TNIK
4.859e-02	-3.02	human chr14q24.2	chromosome location	human chr14q24.2	26	1	26134	50	RGS6
4.859e-02	-3.02	human chr18q12.1	chromosome location	human chr18q12.1	26	1	26134	50	DTNA
4.875e-02	-3.02	chondrosarcoma	COSMIC cancer mutations	chondrosarcoma	1181	7	16828	48	CPE,LRP1B,ERBB4,ADCY2,CNTN1,LSAMP,HPSE2
4.893e-02	-3.02	phosphorylation	biological process	GO:0016310	729	5	18204	50	MAPK10,NTRK2,PRKG1,TNIK,ERBB4
4.905e-02	-3.01	NFIB (nuclear factor I B)	protein interactions	4781	138	2	19454	50	NFIA,SOX5
4.906e-02	-3.01	Integration of energy metabolism	REACTOME pathways	R-HSA-163685	111	2	10285	33	PLCB1,ADCY2
4.931e-02	-3.01	TRIM67 (tripartite motif containing 67)	protein interactions	440730	4804	18	19454	50	CLU,TNIK,APOE,ANK2,PITPNC1,GFAP,TNC,NTM,CTNND2,CNTN1,GPM6A,DTNA,PLCB1,PARD3,PTPRZ1,CTNNA2,RGS6,LSAMP
4.946e-02	-3.01	EF-hand	gene3d domains	1.10.238.10	272	3	14470	44	RYR3,PLCB1,DTNA
4.946e-02	-3.01	knee	COSMIC cancer mutations	knee	125	2	16828	48	ERBB4,CNTN1
4.951e-02	-3.01	cellular response to organonitrogen compound	biological process	GO:0071417	505	4	18204	50	RYR3,SLC1A2,SORBS1,PLCB1
4.961e-02	-3.00	testis-germ_cell_tumour-non_seminoma	COSMIC cancer mutations	testis-germ_cell_tumour-non_seminoma	487	4	16828	48	NTRK2,PRKG1,ERBB4,TNIK
4.968e-02	-3.00	SPCS2 (signal peptidase complex subunit 2)	protein interactions	9789	139	2	19454	50	GPC5,MGAT4C