TermID Term Enrichment logP Genes in Term Target Genes in Term Fraction of Targets in Term Total Target Genes Total Genes Entrez Gene IDs Gene Symbols hsa04970 Salivary secretion 1.49759763440246e-05 -11.1090632178227 90 5 0.192307692307692 26 7161 6263,477,108,5592,23236 RYR3,ATP1A2,ADCY2,PRKG1,PLCB1 ko04970 Salivary secretion 1.49759763440246e-05 -11.1090632178227 90 5 0.192307692307692 26 7161 6263,477,5592,23236,108 RYR3,ATP1A2,PRKG1,PLCB1,ADCY2 hsa04976 Bile secretion 0.000112500337774773 -9.09255433388188 71 4 0.153846153846154 26 7161 108,361,8671,477 ADCY2,AQP4,SLC4A4,ATP1A2 ko04976 Bile secretion 0.000112500337774773 -9.09255433388188 71 4 0.153846153846154 26 7161 8671,477,108,361 SLC4A4,ATP1A2,ADCY2,AQP4 ko04972 Pancreatic secretion 0.000347438536726848 -7.96492278133175 95 4 0.153846153846154 26 7161 477,8671,23236,108 ATP1A2,SLC4A4,PLCB1,ADCY2 hsa04972 Pancreatic secretion 0.000347438536726848 -7.96492278133175 95 4 0.153846153846154 26 7161 8671,477,23236,108 SLC4A4,ATP1A2,PLCB1,ADCY2 ko04713 Circadian entrainment 0.000361652239016508 -7.92482747357379 96 4 0.153846153846154 26 7161 6263,108,23236,5592 RYR3,ADCY2,PLCB1,PRKG1 hsa04713 Circadian entrainment 0.000361652239016508 -7.92482747357379 96 4 0.153846153846154 26 7161 6263,108,23236,5592 RYR3,ADCY2,PLCB1,PRKG1 ko04520 Adherens junction 0.00214659603284203 -6.14387193203091 72 3 0.115384615384615 26 7161 56288,10580,1496 PARD3,SORBS1,CTNNA2 hsa04520 Adherens junction 0.00214659603284203 -6.14387193203091 72 3 0.115384615384615 26 7161 56288,10580,1496 PARD3,SORBS1,CTNNA2 hsa04918 Thyroid hormone synthesis 0.00232199214297837 -6.06532977944241 74 3 0.115384615384615 26 7161 477,108,23236 ATP1A2,ADCY2,PLCB1 ko04918 Thyroid hormone synthesis 0.00232199214297837 -6.06532977944241 74 3 0.115384615384615 26 7161 23236,108,477 PLCB1,ADCY2,ATP1A2 hsa04971 Gastric acid secretion 0.00241293555922437 -6.02691119836333 75 3 0.115384615384615 26 7161 477,23236,108 ATP1A2,PLCB1,ADCY2 ko04971 Gastric acid secretion 0.00241293555922437 -6.02691119836333 75 3 0.115384615384615 26 7161 477,23236,108 ATP1A2,PLCB1,ADCY2 hsa04022 cGMP-PKG signaling pathway 0.00261589787999169 -5.94614788284956 163 4 0.153846153846154 26 7161 477,23236,5592,108 ATP1A2,PLCB1,PRKG1,ADCY2 ko04022 cGMP-PKG signaling pathway 0.00261589787999169 -5.94614788284956 163 4 0.153846153846154 26 7161 477,108,23236,5592 ATP1A2,ADCY2,PLCB1,PRKG1 hsa04964 Proximal tubule bicarbonate reclamation 0.0030603941021922 -5.78921157974469 23 2 0.0769230769230769 26 7161 477,8671 ATP1A2,SLC4A4 ko04964 Proximal tubule bicarbonate reclamation 0.0030603941021922 -5.78921157974469 23 2 0.0769230769230769 26 7161 8671,477 SLC4A4,ATP1A2 hsa04911 Insulin secretion 0.00344565508933788 -5.67064123603727 85 3 0.115384615384615 26 7161 477,108,23236 ATP1A2,ADCY2,PLCB1 hsa04540 Gap junction 0.00380072825221939 -5.57256258529052 88 3 0.115384615384615 26 7161 23236,5592,108 PLCB1,PRKG1,ADCY2 ko04540 Gap junction 0.00380072825221939 -5.57256258529052 88 3 0.115384615384615 26 7161 108,5592,23236 ADCY2,PRKG1,PLCB1 ko04912 GnRH signaling pathway 0.00430791391803887 -5.44730150177276 92 3 0.115384615384615 26 7161 5602,108,23236 MAPK10,ADCY2,PLCB1 hsa04912 GnRH signaling pathway 0.00430791391803887 -5.44730150177276 92 3 0.115384615384615 26 7161 23236,108,5602 PLCB1,ADCY2,MAPK10 ko04750 Inflammatory mediator regulation of TRP channels 0.00499746090554157 -5.29882531442341 97 3 0.115384615384615 26 7161 23236,108,5602 PLCB1,ADCY2,MAPK10 hsa04750 Inflammatory mediator regulation of TRP channels 0.00499746090554157 -5.29882531442341 97 3 0.115384615384615 26 7161 5602,108,23236 MAPK10,ADCY2,PLCB1 ko04723 Retrograde endocannabinoid signaling 0.005594620633183 -5.18594974413138 101 3 0.115384615384615 26 7161 5602,108,23236 MAPK10,ADCY2,PLCB1 hsa04723 Retrograde endocannabinoid signaling 0.005594620633183 -5.18594974413138 101 3 0.115384615384615 26 7161 23236,108,5602 PLCB1,ADCY2,MAPK10 hsa04724 Glutamatergic synapse 0.00782482193570919 -4.85045429863475 114 3 0.115384615384615 26 7161 6506,108,23236 SLC1A2,ADCY2,PLCB1 ko04724 Glutamatergic synapse 0.00782482193570919 -4.85045429863475 114 3 0.115384615384615 26 7161 108,23236,6506 ADCY2,PLCB1,SLC1A2 ko04270 Vascular smooth muscle contraction 0.00921510577481954 -4.68691120937826 121 3 0.115384615384615 26 7161 23236,5592,108 PLCB1,PRKG1,ADCY2 hsa04270 Vascular smooth muscle contraction 0.00921510577481954 -4.68691120937826 121 3 0.115384615384615 26 7161 108,5592,23236 ADCY2,PRKG1,PLCB1 hsa04611 Platelet activation 0.00963731087545128 -4.64211316410352 123 3 0.115384615384615 26 7161 108,5592,23236 ADCY2,PRKG1,PLCB1 ko04961 Endocrine and other factor-regulated calcium reabsorption 0.0123964551830487 -4.39034471957521 47 2 0.0769230769230769 26 7161 477,23236 ATP1A2,PLCB1 hsa04961 Endocrine and other factor-regulated calcium reabsorption 0.0123964551830487 -4.39034471957521 47 2 0.0769230769230769 26 7161 477,23236 ATP1A2,PLCB1 hsa04371 Apelin signaling pathway 0.0131657133275598 -4.33013930386637 138 3 0.115384615384615 26 7161 23236,108,6263 PLCB1,ADCY2,RYR3 ko04261 Adrenergic signaling in cardiomyocytes 0.0147590176003062 -4.21590102026975 144 3 0.115384615384615 26 7161 477,23236,108 ATP1A2,PLCB1,ADCY2 hsa04261 Adrenergic signaling in cardiomyocytes 0.0147590176003062 -4.21590102026975 144 3 0.115384615384615 26 7161 23236,108,477 PLCB1,ADCY2,ATP1A2 hsa04923 Regulation of lipolysis in adipocytes 0.0161572948008968 -4.12538364083689 54 2 0.0769230769230769 26 7161 108,5592 ADCY2,PRKG1 ko04921 Oxytocin signaling pathway 0.0170479793205569 -4.07172359719941 152 3 0.115384615384615 26 7161 23236,108,6263 PLCB1,ADCY2,RYR3 hsa04921 Oxytocin signaling pathway 0.0170479793205569 -4.07172359719941 152 3 0.115384615384615 26 7161 108,23236,6263 ADCY2,PLCB1,RYR3 ko04730 Long-term depression 0.01972104182174 -3.9260691004861 60 2 0.0769230769230769 26 7161 23236,5592 PLCB1,PRKG1 hsa04730 Long-term depression 0.01972104182174 -3.9260691004861 60 2 0.0769230769230769 26 7161 5592,23236 PRKG1,PLCB1 ko05010 Alzheimer's disease 0.0211730841802516 -3.8550245180861 165 3 0.115384615384615 26 7161 23236,348,6263 PLCB1,APOE,RYR3 hsa05010 Alzheimer's disease 0.0211730841802516 -3.8550245180861 165 3 0.115384615384615 26 7161 6263,23236,348 RYR3,PLCB1,APOE ko05120 Epithelial cell signaling in Helicobacter pylori infection 0.0249358429425149 -3.6914490349603 68 2 0.0769230769230769 26 7161 5602,5803 MAPK10,PTPRZ1 hsa05120 Epithelial cell signaling in Helicobacter pylori infection 0.0249358429425149 -3.6914490349603 68 2 0.0769230769230769 26 7161 5803,5602 PTPRZ1,MAPK10 hsa04020 Calcium signaling pathway 0.0269454320947462 -3.61394149154985 181 3 0.115384615384615 26 7161 6263,108,23236 RYR3,ADCY2,PLCB1 ko04020 Calcium signaling pathway 0.0269454320947462 -3.61394149154985 181 3 0.115384615384615 26 7161 6263,23236,108 RYR3,PLCB1,ADCY2 ko04062 Chemokine signaling pathway 0.0273317516371601 -3.59970618899352 182 3 0.115384615384615 26 7161 23236,108,56288 PLCB1,ADCY2,PARD3 hsa04062 Chemokine signaling pathway 0.0273317516371601 -3.59970618899352 182 3 0.115384615384615 26 7161 108,23236,56288 ADCY2,PLCB1,PARD3 hsa_M00078 Heparan sulfate degradation 0.032224170549981 -3.43503846982155 9 1 0.0384615384615385 26 7161 60495 HPSE2 M00078 Heparan sulfate degradation 0.032224170549981 -3.43503846982155 9 1 0.0384615384615385 26 7161 60495 HPSE2 hsa_M00694 cGMP signaling 0.032224170549981 -3.43503846982155 9 1 0.0384615384615385 26 7161 5592 PRKG1 M00694 cGMP signaling 0.032224170549981 -3.43503846982155 9 1 0.0384615384615385 26 7161 5592 PRKG1 ko04024 cAMP signaling pathway 0.0339208747605993 -3.3837246794582 198 3 0.115384615384615 26 7161 5602,477,108 MAPK10,ATP1A2,ADCY2 hsa04024 cAMP signaling pathway 0.0339208747605993 -3.3837246794582 198 3 0.115384615384615 26 7161 477,5602,108 ATP1A2,MAPK10,ADCY2 ko04925 Aldosterone synthesis and secretion 0.035246579536131 -3.345386788868 82 2 0.0769230769230769 26 7161 108,23236 ADCY2,PLCB1 hsa04925 Aldosterone synthesis and secretion 0.035246579536131 -3.345386788868 82 2 0.0769230769230769 26 7161 108,23236 ADCY2,PLCB1 M00035 Methionine degradation 0.0357423712722646 -3.33141842359882 10 1 0.0384615384615385 26 7161 10768 AHCYL1 hsa_M00035 Methionine degradation 0.0357423712722646 -3.33141842359882 10 1 0.0384615384615385 26 7161 10768 AHCYL1 hsa04012 ErbB signaling pathway 0.0376395940126737 -3.27969875038387 85 2 0.0769230769230769 26 7161 5602,10718 MAPK10,NRG3 ko04012 ErbB signaling pathway 0.0376395940126737 -3.27969875038387 85 2 0.0769230769230769 26 7161 10718,5602 NRG3,MAPK10 hsa04015 Rap1 signaling pathway 0.039363942505034 -3.23490504654412 210 3 0.115384615384615 26 7161 56288,108,23236 PARD3,ADCY2,PLCB1 ko04015 Rap1 signaling pathway 0.039363942505034 -3.23490504654412 210 3 0.115384615384615 26 7161 23236,108,56288 PLCB1,ADCY2,PARD3 hsa04914 Progesterone-mediated oocyte maturation 0.043459296757761 -3.13593048565244 92 2 0.0769230769230769 26 7161 5602,108 MAPK10,ADCY2 ko04914 Progesterone-mediated oocyte maturation 0.043459296757761 -3.13593048565244 92 2 0.0769230769230769 26 7161 108,5602 ADCY2,MAPK10 ko01522 Endocrine resistance 0.0460510217858725 -3.07800532790869 95 2 0.0769230769230769 26 7161 108,5602 ADCY2,MAPK10 hsa01522 Endocrine resistance 0.0460510217858725 -3.07800532790869 95 2 0.0769230769230769 26 7161 5602,108 MAPK10,ADCY2 ko04915 Estrogen signaling pathway 0.0486991846931734 -3.02209299044701 98 2 0.0769230769230769 26 7161 23236,108 PLCB1,ADCY2 hsa04915 Estrogen signaling pathway 0.0486991846931734 -3.02209299044701 98 2 0.0769230769230769 26 7161 23236,108 PLCB1,ADCY2 hsa04933 AGE-RAGE signaling pathway in diabetic complications 0.0495942004278224 -3.00388137894615 99 2 0.0769230769230769 26 7161 23236,5602 PLCB1,MAPK10 ko04933 AGE-RAGE signaling pathway in diabetic complications 0.0495942004278224 -3.00388137894615 99 2 0.0769230769230769 26 7161 5602,23236 MAPK10,PLCB1 hsa04916 Melanogenesis 0.0514023602064008 -2.96807118916277 101 2 0.0769230769230769 26 7161 108,23236 ADCY2,PLCB1 ko04916 Melanogenesis 0.0514023602064008 -2.96807118916277 101 2 0.0769230769230769 26 7161 23236,108 PLCB1,ADCY2 hsa05200 Pathways in cancer 0.05208436291608 -2.95489051124038 395 4 0.153846153846154 26 7161 5602,1496,108,23236 MAPK10,CTNNA2,ADCY2,PLCB1 ko04922 Glucagon signaling pathway 0.0523154005897992 -2.95046448491381 102 2 0.0769230769230769 26 7161 108,23236 ADCY2,PLCB1 hsa04922 Glucagon signaling pathway 0.0523154005897992 -2.95046448491381 102 2 0.0769230769230769 26 7161 108,23236 ADCY2,PLCB1 hsa05142 Chagas disease (American trypanosomiasis) 0.0523154005897992 -2.95046448491381 102 2 0.0769230769230769 26 7161 23236,5602 PLCB1,MAPK10 ko05142 Chagas disease (American trypanosomiasis) 0.0523154005897992 -2.95046448491381 102 2 0.0769230769230769 26 7161 23236,5602 PLCB1,MAPK10 hsa_M00075 N-glycan biosynthesis, complex type 0.0565947226637449 -2.87183953727649 16 1 0.0384615384615385 26 7161 25834 MGAT4C M00075 N-glycan biosynthesis, complex type 0.0565947226637449 -2.87183953727649 16 1 0.0384615384615385 26 7161 25834 MGAT4C M00695 cAMP signaling 0.0565947226637449 -2.87183953727649 16 1 0.0384615384615385 26 7161 108 ADCY2 hsa_M00695 cAMP signaling 0.0565947226637449 -2.87183953727649 16 1 0.0384615384615385 26 7161 108 ADCY2 ko04659 Th17 cell differentiation 0.056968158571233 -2.86526278879206 107 2 0.0769230769230769 26 7161 5602,6095 MAPK10,RORA hsa04659 Th17 cell differentiation 0.056968158571233 -2.86526278879206 107 2 0.0769230769230769 26 7161 5602,6095 MAPK10,RORA hsa04725 Cholinergic synapse 0.0617622273733332 -2.78446330893322 112 2 0.0769230769230769 26 7161 108,23236 ADCY2,PLCB1 hsa04919 Thyroid hormone signaling pathway 0.0656950790843493 -2.72273125607829 116 2 0.0769230769230769 26 7161 23236,477 PLCB1,ATP1A2 hsa00531 Glycosaminoglycan degradation 0.0668576186184816 -2.70519001605672 19 1 0.0384615384615385 26 7161 60495 HPSE2 ko00531 Glycosaminoglycan degradation 0.0668576186184816 -2.70519001605672 19 1 0.0384615384615385 26 7161 60495 HPSE2 ko04071 Sphingolipid signaling pathway 0.0676929737987106 -2.69277288881161 118 2 0.0769230769230769 26 7161 5602,23236 MAPK10,PLCB1 hsa04071 Sphingolipid signaling pathway 0.0676929737987106 -2.69277288881161 118 2 0.0769230769230769 26 7161 5602,23236 MAPK10,PLCB1 ko04722 Neurotrophin signaling pathway 0.0686996218774617 -2.67801158373606 119 2 0.0769230769230769 26 7161 5602,4915 MAPK10,NTRK2 hsa04722 Neurotrophin signaling pathway 0.0686996218774617 -2.67801158373606 119 2 0.0769230769230769 26 7161 5602,4915 MAPK10,NTRK2 hsa_M00688 MAPK (JNK) signaling 0.073639817693518 -2.60856939826511 21 1 0.0384615384615385 26 7161 5602 MAPK10 M00688 MAPK (JNK) signaling 0.073639817693518 -2.60856939826511 21 1 0.0384615384615385 26 7161 5602 MAPK10 M00130 Inositol phosphate metabolism, PI=> PIP2 => Ins(1,4,5)P3 => Ins(1,3,4,5)P4 0.0770131180781056 -2.56377950698814 22 1 0.0384615384615385 26 7161 23236 PLCB1 hsa_M00130 Inositol phosphate metabolism, PI=> PIP2 => Ins(1,4,5)P3 => Ins(1,3,4,5)P4 0.0770131180781056 -2.56377950698814 22 1 0.0384615384615385 26 7161 23236 PLCB1 hsa04728 Dopaminergic synapse 0.0800972777737063 -2.52451341083233 130 2 0.0769230769230769 26 7161 5602,23236 MAPK10,PLCB1 ko04728 Dopaminergic synapse 0.0800972777737063 -2.52451341083233 130 2 0.0769230769230769 26 7161 5602,23236 MAPK10,PLCB1 ko04910 Insulin signaling pathway 0.0887373296917764 -2.42207462485469 138 2 0.0769230769230769 26 7161 10580,5602 SORBS1,MAPK10 hsa04910 Insulin signaling pathway 0.0887373296917764 -2.42207462485469 138 2 0.0769230769230769 26 7161 10580,5602 SORBS1,MAPK10 hsa04310 Wnt signaling pathway 0.0942760580590061 -2.3615280127874 143 2 0.0769230769230769 26 7161 5602,23236 MAPK10,PLCB1 ko04310 Wnt signaling pathway 0.0942760580590061 -2.3615280127874 143 2 0.0769230769230769 26 7161 5602,23236 MAPK10,PLCB1 hsa04072 Phospholipase D signaling pathway 0.0965199492245369 -2.33800556428702 145 2 0.0769230769230769 26 7161 23236,108 PLCB1,ADCY2 ko04072 Phospholipase D signaling pathway 0.0965199492245369 -2.33800556428702 145 2 0.0769230769230769 26 7161 23236,108 PLCB1,ADCY2 hsa04320 Dorso-ventral axis formation 0.0970062345179061 -2.33298002916372 28 1 0.0384615384615385 26 7161 56776 FMN2 ko04320 Dorso-ventral axis formation 0.0970062345179061 -2.33298002916372 28 1 0.0384615384615385 26 7161 56776 FMN2 ko04390 Hippo signaling pathway 0.106807533384809 -2.23672681763273 154 2 0.0769230769230769 26 7161 56288,1496 PARD3,CTNNA2 hsa04390 Hippo signaling pathway 0.106807533384809 -2.23672681763273 154 2 0.0769230769230769 26 7161 56288,1496 PARD3,CTNNA2 hsa04710 Circadian rhythm 0.10684597910041 -2.23636692917999 31 1 0.0384615384615385 26 7161 6095 RORA ko04710 Circadian rhythm 0.10684597910041 -2.23636692917999 31 1 0.0384615384615385 26 7161 6095 RORA ko04215 Apoptosis - multiple species 0.113348443908361 -2.17728863032432 33 1 0.0384615384615385 26 7161 5602 MAPK10 hsa04215 Apoptosis - multiple species 0.113348443908361 -2.17728863032432 33 1 0.0384615384615385 26 7161 5602 MAPK10 hsa05143 African trypanosomiasis 0.116582582581808 -2.14915539373818 34 1 0.0384615384615385 26 7161 23236 PLCB1 ko05143 African trypanosomiasis 0.116582582581808 -2.14915539373818 34 1 0.0384615384615385 26 7161 23236 PLCB1 ko04621 NOD-like receptor signaling pathway 0.124583784858476 -2.08277681866984 169 2 0.0769230769230769 26 7161 23236,5602 PLCB1,MAPK10 hsa04621 NOD-like receptor signaling pathway 0.124583784858476 -2.08277681866984 169 2 0.0769230769230769 26 7161 5602,23236 MAPK10,PLCB1 hsa04530 Tight junction 0.125794373706421 -2.07310665983025 170 2 0.0769230769230769 26 7161 5602,56288 MAPK10,PARD3 ko04530 Tight junction 0.125794373706421 -2.07310665983025 170 2 0.0769230769230769 26 7161 5602,56288 MAPK10,PARD3 hsa04960 Aldosterone-regulated sodium reabsorption 0.126217083285355 -2.06975197127435 37 1 0.0384615384615385 26 7161 477 ATP1A2 ko04960 Aldosterone-regulated sodium reabsorption 0.126217083285355 -2.06975197127435 37 1 0.0384615384615385 26 7161 477 ATP1A2 ko04360 Axon guidance 0.130666203852657 -2.03510926981001 174 2 0.0769230769230769 26 7161 56288,3983 PARD3,ABLIM1 hsa04360 Axon guidance 0.130666203852657 -2.03510926981001 174 2 0.0769230769230769 26 7161 3983,56288 ABLIM1,PARD3 hsa04940 Type I diabetes mellitus 0.145183879649123 -1.92975420445506 43 1 0.0384615384615385 26 7161 1363 CPE ko04940 Type I diabetes mellitus 0.145183879649123 -1.92975420445506 43 1 0.0384615384615385 26 7161 1363 CPE hsa00270 Cysteine and methionine metabolism 0.148306276265824 -1.90847570931892 44 1 0.0384615384615385 26 7161 10768 AHCYL1 ko04973 Carbohydrate digestion and absorption 0.148306276265824 -1.90847570931892 44 1 0.0384615384615385 26 7161 477 ATP1A2 hsa04973 Carbohydrate digestion and absorption 0.148306276265824 -1.90847570931892 44 1 0.0384615384615385 26 7161 477 ATP1A2 ko04962 Vasopressin-regulated water reabsorption 0.148306276265824 -1.90847570931892 44 1 0.0384615384615385 26 7161 361 AQP4 ko00270 Cysteine and methionine metabolism 0.148306276265824 -1.90847570931892 44 1 0.0384615384615385 26 7161 10768 AHCYL1 hsa04962 Vasopressin-regulated water reabsorption 0.148306276265824 -1.90847570931892 44 1 0.0384615384615385 26 7161 361 AQP4 ko04930 Type II diabetes mellitus 0.154518202217431 -1.86744337587877 46 1 0.0384615384615385 26 7161 5602 MAPK10 hsa04930 Type II diabetes mellitus 0.154518202217431 -1.86744337587877 46 1 0.0384615384615385 26 7161 5602 MAPK10 hsa00510 N-Glycan biosynthesis 0.163754476014754 -1.80938707039911 49 1 0.0384615384615385 26 7161 25834 MGAT4C ko00510 N-Glycan biosynthesis 0.163754476014754 -1.80938707039911 49 1 0.0384615384615385 26 7161 25834 MGAT4C ko04913 Ovarian steroidogenesis 0.166811616567784 -1.79089014779075 50 1 0.0384615384615385 26 7161 108 ADCY2 hsa05213 Endometrial cancer 0.166811616567784 -1.79089014779075 50 1 0.0384615384615385 26 7161 1496 CTNNA2 hsa04913 Ovarian steroidogenesis 0.166811616567784 -1.79089014779075 50 1 0.0384615384615385 26 7161 108 ADCY2 ko05213 Endometrial cancer 0.166811616567784 -1.79089014779075 50 1 0.0384615384615385 26 7161 1496 CTNNA2 ko05014 Amyotrophic lateral sclerosis (ALS) 0.169858009197188 -1.77279243095571 51 1 0.0384615384615385 26 7161 6506 SLC1A2 hsa05014 Amyotrophic lateral sclerosis (ALS) 0.169858009197188 -1.77279243095571 51 1 0.0384615384615385 26 7161 6506 SLC1A2 ko04978 Mineral absorption 0.169858009197188 -1.77279243095571 51 1 0.0384615384615385 26 7161 477 ATP1A2 hsa04978 Mineral absorption 0.169858009197188 -1.77279243095571 51 1 0.0384615384615385 26 7161 477 ATP1A2 hsa05210 Colorectal cancer 0.196797833710374 -1.6255783019938 60 1 0.0384615384615385 26 7161 5602 MAPK10 ko05210 Colorectal cancer 0.196797833710374 -1.6255783019938 60 1 0.0384615384615385 26 7161 5602 MAPK10 ko04213 Longevity regulating pathway - multiple species 0.202669257461922 -1.59617990223657 62 1 0.0384615384615385 26 7161 108 ADCY2 hsa04213 Longevity regulating pathway - multiple species 0.202669257461922 -1.59617990223657 62 1 0.0384615384615385 26 7161 108 ADCY2 hsa04137 Mitophagy - animal 0.208499400155702 -1.56781911469849 64 1 0.0384615384615385 26 7161 5602 MAPK10 hsa05212 Pancreatic cancer 0.208499400155702 -1.56781911469849 64 1 0.0384615384615385 26 7161 5602 MAPK10 hsa05131 Shigellosis 0.208499400155702 -1.56781911469849 64 1 0.0384615384615385 26 7161 5602 MAPK10 ko04137 Mitophagy - animal 0.208499400155702 -1.56781911469849 64 1 0.0384615384615385 26 7161 5602 MAPK10 ko05212 Pancreatic cancer 0.208499400155702 -1.56781911469849 64 1 0.0384615384615385 26 7161 5602 MAPK10 hsa05321 Inflammatory bowel disease (IBD) 0.211399078270266 -1.55400756567724 65 1 0.0384615384615385 26 7161 6095 RORA ko04924 Renin secretion 0.211399078270266 -1.55400756567724 65 1 0.0384615384615385 26 7161 23236 PLCB1 ko05321 Inflammatory bowel disease (IBD) 0.211399078270266 -1.55400756567724 65 1 0.0384615384615385 26 7161 6095 RORA hsa04924 Renin secretion 0.211399078270266 -1.55400756567724 65 1 0.0384615384615385 26 7161 23236 PLCB1 hsa04664 Fc epsilon RI signaling pathway 0.217167821393588 -1.52708485386117 67 1 0.0384615384615385 26 7161 5602 MAPK10 ko04720 Long-term potentiation 0.217167821393588 -1.52708485386117 67 1 0.0384615384615385 26 7161 23236 PLCB1 ko04664 Fc epsilon RI signaling pathway 0.217167821393588 -1.52708485386117 67 1 0.0384615384615385 26 7161 5602 MAPK10 hsa04720 Long-term potentiation 0.217167821393588 -1.52708485386117 67 1 0.0384615384615385 26 7161 23236 PLCB1 ko04920 Adipocytokine signaling pathway 0.222895976852421 -1.50105008786751 69 1 0.0384615384615385 26 7161 5602 MAPK10 hsa04920 Adipocytokine signaling pathway 0.222895976852421 -1.50105008786751 69 1 0.0384615384615385 26 7161 5602 MAPK10 hsa04622 RIG-I-like receptor signaling pathway 0.225744919970992 -1.48834958983528 70 1 0.0384615384615385 26 7161 5602 MAPK10 hsa04917 Prolactin signaling pathway 0.225744919970992 -1.48834958983528 70 1 0.0384615384615385 26 7161 5602 MAPK10 ko04917 Prolactin signaling pathway 0.225744919970992 -1.48834958983528 70 1 0.0384615384615385 26 7161 5602 MAPK10 ko04622 RIG-I-like receptor signaling pathway 0.225744919970992 -1.48834958983528 70 1 0.0384615384615385 26 7161 5602 MAPK10 ko00562 Inositol phosphate metabolism 0.22858381887035 -1.47585231372097 71 1 0.0384615384615385 26 7161 23236 PLCB1 hsa00562 Inositol phosphate metabolism 0.22858381887035 -1.47585231372097 71 1 0.0384615384615385 26 7161 23236 PLCB1 ko03320 PPAR signaling pathway 0.231412707542423 -1.46355254981672 72 1 0.0384615384615385 26 7161 10580 SORBS1 hsa03320 PPAR signaling pathway 0.231412707542423 -1.46355254981672 72 1 0.0384615384615385 26 7161 10580 SORBS1 ko05412 Arrhythmogenic right ventricular cardiomyopathy (ARVC) 0.231412707542423 -1.46355254981672 72 1 0.0384615384615385 26 7161 1496 CTNNA2 hsa05412 Arrhythmogenic right ventricular cardiomyopathy (ARVC) 0.231412707542423 -1.46355254981672 72 1 0.0384615384615385 26 7161 1496 CTNNA2 ko04010 MAPK signaling pathway 0.236372101500052 -1.44234801437356 255 2 0.0769230769230769 26 7161 5602,4915 MAPK10,NTRK2 hsa04010 MAPK signaling pathway 0.236372101500052 -1.44234801437356 255 2 0.0769230769230769 26 7161 4915,5602 NTRK2,MAPK10 hsa04260 Cardiac muscle contraction 0.237040589682841 -1.43952388802653 74 1 0.0384615384615385 26 7161 477 ATP1A2 ko04260 Cardiac muscle contraction 0.237040589682841 -1.43952388802653 74 1 0.0384615384615385 26 7161 477 ATP1A2 ko05133 Pertussis 0.242628836173698 -1.41622242649504 76 1 0.0384615384615385 26 7161 5602 MAPK10 ko05100 Bacterial invasion of epithelial cells 0.242628836173698 -1.41622242649504 76 1 0.0384615384615385 26 7161 1496 CTNNA2 hsa05133 Pertussis 0.242628836173698 -1.41622242649504 76 1 0.0384615384615385 26 7161 5602 MAPK10 hsa05100 Bacterial invasion of epithelial cells 0.242628836173698 -1.41622242649504 76 1 0.0384615384615385 26 7161 1496 CTNNA2 ko04610 Complement and coagulation cascades 0.250937475000497 -1.38255147446548 79 1 0.0384615384615385 26 7161 1191 CLU hsa04610 Complement and coagulation cascades 0.250937475000497 -1.38255147446548 79 1 0.0384615384615385 26 7161 1191 CLU ko05132 Salmonella infection 0.267292600949262 -1.31941133691899 85 1 0.0384615384615385 26 7161 5602 MAPK10 hsa05132 Salmonella infection 0.267292600949262 -1.31941133691899 85 1 0.0384615384615385 26 7161 5602 MAPK10 ko04727 GABAergic synapse 0.275340856726846 -1.28974546982881 88 1 0.0384615384615385 26 7161 108 ADCY2 hsa04727 GABAergic synapse 0.275340856726846 -1.28974546982881 88 1 0.0384615384615385 26 7161 108 ADCY2 hsa05414 Dilated cardiomyopathy 0.278004668083889 -1.28011737376381 89 1 0.0384615384615385 26 7161 108 ADCY2 ko04974 Protein digestion and absorption 0.278004668083889 -1.28011737376381 89 1 0.0384615384615385 26 7161 477 ATP1A2 hsa04211 Longevity regulating pathway 0.278004668083889 -1.28011737376381 89 1 0.0384615384615385 26 7161 108 ADCY2 hsa04974 Protein digestion and absorption 0.278004668083889 -1.28011737376381 89 1 0.0384615384615385 26 7161 477 ATP1A2 ko05414 Dilated cardiomyopathy 0.278004668083889 -1.28011737376381 89 1 0.0384615384615385 26 7161 108 ADCY2 ko03015 mRNA surveillance pathway 0.283304072498135 -1.26123449703496 91 1 0.0384615384615385 26 7161 124540 MSI2 ko05032 Morphine addiction 0.283304072498135 -1.26123449703496 91 1 0.0384615384615385 26 7161 108 ADCY2 hsa05032 Morphine addiction 0.283304072498135 -1.26123449703496 91 1 0.0384615384615385 26 7161 108 ADCY2 hsa03015 mRNA surveillance pathway 0.283304072498135 -1.26123449703496 91 1 0.0384615384615385 26 7161 124540 MSI2 ko04658 Th1 and Th2 cell differentiation 0.285939729372854 -1.25197422682889 92 1 0.0384615384615385 26 7161 5602 MAPK10 hsa04658 Th1 and Th2 cell differentiation 0.285939729372854 -1.25197422682889 92 1 0.0384615384615385 26 7161 5602 MAPK10 ko04657 IL-17 signaling pathway 0.288566065069032 -1.24283122420937 93 1 0.0384615384615385 26 7161 5602 MAPK10 hsa04657 IL-17 signaling pathway 0.288566065069032 -1.24283122420937 93 1 0.0384615384615385 26 7161 5602 MAPK10 ko05146 Amoebiasis 0.291183111235237 -1.23380296147325 94 1 0.0384615384615385 26 7161 23236 PLCB1 hsa05146 Amoebiasis 0.291183111235237 -1.23380296147325 94 1 0.0384615384615385 26 7161 23236 PLCB1 hsa04070 Phosphatidylinositol signaling system 0.298978827524833 -1.2073825190524 97 1 0.0384615384615385 26 7161 23236 PLCB1 ko04070 Phosphatidylinositol signaling system 0.298978827524833 -1.2073825190524 97 1 0.0384615384615385 26 7161 23236 PLCB1 ko05231 Choline metabolism in cancer 0.304130099720085 -1.19029970951897 99 1 0.0384615384615385 26 7161 5602 MAPK10 hsa05231 Choline metabolism in cancer 0.304130099720085 -1.19029970951897 99 1 0.0384615384615385 26 7161 5602 MAPK10 hsa04620 Toll-like receptor signaling pathway 0.316849538747652 -1.14932825895724 104 1 0.0384615384615385 26 7161 5602 MAPK10 ko04620 Toll-like receptor signaling pathway 0.316849538747652 -1.14932825895724 104 1 0.0384615384615385 26 7161 5602 MAPK10 hsa04931 Insulin resistance 0.324373579304697 -1.12585940486442 107 1 0.0384615384615385 26 7161 5602 MAPK10 hsa04668 TNF signaling pathway 0.326863838302144 -1.11821159143156 108 1 0.0384615384615385 26 7161 5602 MAPK10 ko04668 TNF signaling pathway 0.326863838302144 -1.11821159143156 108 1 0.0384615384615385 26 7161 5602 MAPK10 hsa04726 Serotonergic synapse 0.336736904695387 -1.08845335176662 112 1 0.0384615384615385 26 7161 23236 PLCB1 hsa05145 Toxoplasmosis 0.339183328366596 -1.08121452613491 113 1 0.0384615384615385 26 7161 5602 MAPK10 ko05145 Toxoplasmosis 0.339183328366596 -1.08121452613491 113 1 0.0384615384615385 26 7161 5602 MAPK10 hsa04670 Leukocyte transendothelial migration 0.341621074322057 -1.07405312599039 114 1 0.0384615384615385 26 7161 1496 CTNNA2 ko04670 Leukocyte transendothelial migration 0.341621074322057 -1.07405312599039 114 1 0.0384615384615385 26 7161 1496 CTNNA2 ko04114 Oocyte meiosis 0.356066966121625 -1.03263645873681 120 1 0.0384615384615385 26 7161 108 ADCY2 hsa04114 Oocyte meiosis 0.356066966121625 -1.03263645873681 120 1 0.0384615384615385 26 7161 108 ADCY2 ko04140 Autophagy - animal 0.372535415058977 -0.987423171697935 127 1 0.0384615384615385 26 7161 5602 MAPK10 hsa04140 Autophagy - animal 0.372535415058977 -0.987423171697935 127 1 0.0384615384615385 26 7161 5602 MAPK10 ko04380 Osteoclast differentiation 0.377165805634094 -0.975070385476051 129 1 0.0384615384615385 26 7161 5602 MAPK10 hsa04380 Osteoclast differentiation 0.377165805634094 -0.975070385476051 129 1 0.0384615384615385 26 7161 5602 MAPK10 hsa05160 Hepatitis C 0.381763331012868 -0.962954414699745 131 1 0.0384615384615385 26 7161 5602 MAPK10 ko05160 Hepatitis C 0.381763331012868 -0.962954414699745 131 1 0.0384615384615385 26 7161 5602 MAPK10 hsa04068 FoxO signaling pathway 0.384049839323606 -0.956982944911166 132 1 0.0384615384615385 26 7161 5602 MAPK10 ko04210 Apoptosis 0.397599077382122 -0.922311124669909 138 1 0.0384615384615385 26 7161 5602 MAPK10 hsa04210 Apoptosis 0.397599077382122 -0.922311124669909 138 1 0.0384615384615385 26 7161 5602 MAPK10 hsa05418 Fluid shear stress and atherosclerosis 0.406472192281772 -0.900239760005102 142 1 0.0384615384615385 26 7161 5602 MAPK10 ko05418 Fluid shear stress and atherosclerosis 0.406472192281772 -0.900239760005102 142 1 0.0384615384615385 26 7161 5602 MAPK10 ko04514 Cell adhesion molecules (CAMs) 0.408670756607841 -0.894845443191508 143 1 0.0384615384615385 26 7161 9378 NRXN1 hsa04514 Cell adhesion molecules (CAMs) 0.408670756607841 -0.894845443191508 143 1 0.0384615384615385 26 7161 9378 NRXN1 hsa05161 Hepatitis B 0.410861489048635 -0.889499130900432 144 1 0.0384615384615385 26 7161 5602 MAPK10 hsa04932 Non-alcoholic fatty liver disease (NAFLD) 0.41304441640831 -0.884200146020904 145 1 0.0384615384615385 26 7161 5602 MAPK10 ko04932 Non-alcoholic fatty liver disease (NAFLD) 0.41304441640831 -0.884200146020904 145 1 0.0384615384615385 26 7161 5602 MAPK10 hsa04141 Protein processing in endoplasmic reticulum 0.455104378586481 -0.787228482853372 165 1 0.0384615384615385 26 7161 5602 MAPK10 ko04141 Protein processing in endoplasmic reticulum 0.455104378586481 -0.787228482853372 165 1 0.0384615384615385 26 7161 5602 MAPK10 ko05164 Influenza A 0.469128643655162 -0.756878254639636 172 1 0.0384615384615385 26 7161 5602 MAPK10 hsa05164 Influenza A 0.469128643655162 -0.756878254639636 172 1 0.0384615384615385 26 7161 5602 MAPK10 hsa00230 Purine metabolism 0.471103554986012 -0.752677347165764 173 1 0.0384615384615385 26 7161 108 ADCY2 ko00230 Purine metabolism 0.471103554986012 -0.752677347165764 173 1 0.0384615384615385 26 7161 108 ADCY2 hsa05152 Tuberculosis 0.480872615299103 -0.73215287700884 178 1 0.0384615384615385 26 7161 5602 MAPK10 ko05152 Tuberculosis 0.480872615299103 -0.73215287700884 178 1 0.0384615384615385 26 7161 5602 MAPK10 ko05034 Alcoholism 0.484731457494799 -0.724160237277842 180 1 0.0384615384615385 26 7161 4915 NTRK2 hsa05034 Alcoholism 0.484731457494799 -0.724160237277842 180 1 0.0384615384615385 26 7161 4915 NTRK2 ko05168 Herpes simplex infection 0.494258276481304 -0.704697071535341 185 1 0.0384615384615385 26 7161 5602 MAPK10 hsa05168 Herpes simplex infection 0.494258276481304 -0.704697071535341 185 1 0.0384615384615385 26 7161 5602 MAPK10 ko05016 Huntington's disease 0.498021384216766 -0.697112262685078 187 1 0.0384615384615385 26 7161 23236 PLCB1 hsa05016 Huntington's disease 0.498021384216766 -0.697112262685078 187 1 0.0384615384615385 26 7161 23236 PLCB1 ko04510 Focal adhesion 0.518242015684552 -0.657312934085838 198 1 0.0384615384615385 26 7161 5602 MAPK10 hsa04510 Focal adhesion 0.518242015684552 -0.657312934085838 198 1 0.0384615384615385 26 7161 5602 MAPK10 hsa05169 Epstein-Barr virus infection 0.520040910935646 -0.653847795625128 199 1 0.0384615384615385 26 7161 5602 MAPK10 ko05169 Epstein-Barr virus infection 0.520040910935646 -0.653847795625128 199 1 0.0384615384615385 26 7161 5602 MAPK10 hsa05205 Proteoglycans in cancer 0.527172117337057 -0.640228185399874 203 1 0.0384615384615385 26 7161 60495 HPSE2 ko05205 Proteoglycans in cancer 0.527172117337057 -0.640228185399874 203 1 0.0384615384615385 26 7161 60495 HPSE2 hsa04014 Ras signaling pathway 0.566240796123275 -0.568735856403923 226 1 0.0384615384615385 26 7161 5602 MAPK10 hsa05166 HTLV-I infection 0.612557092911214 -0.490113127991041 256 1 0.0384615384615385 26 7161 108 ADCY2 ko05166 HTLV-I infection 0.612557092911214 -0.490113127991041 256 1 0.0384615384615385 26 7161 108 ADCY2 hsa04144 Endocytosis 0.618360960628165 -0.480682913345662 260 1 0.0384615384615385 26 7161 56288 PARD3 ko04144 Endocytosis 0.618360960628165 -0.480682913345662 260 1 0.0384615384615385 26 7161 56288 PARD3 ko04080 Neuroactive ligand-receptor interaction 0.64075147566187 -0.445113610717791 276 1 0.0384615384615385 26 7161 56288 PARD3 hsa04080 Neuroactive ligand-receptor interaction 0.64075147566187 -0.445113610717791 276 1 0.0384615384615385 26 7161 56288 PARD3 hsa01100 Metabolic pathways 0.693160337281716 -0.366493939624551 1256 4 0.153846153846154 26 7161 23236,60495,25834,10768 PLCB1,HPSE2,MGAT4C,AHCYL1 hsa04740 Olfactory transduction 0.78880981681329 -0.237230030521039 415 1 0.0384615384615385 26 7161 5592 PRKG1 ko04740 Olfactory transduction 0.78880981681329 -0.237230030521039 415 1 0.0384615384615385 26 7161 5592 PRKG1 hsa05224 Breast cancer 0.999999999981048 -1.89517716334358e-11 144 0 0 26 7161 ko05224 Breast cancer 0.999999999981048 -1.89517716334358e-11 144 0 0 26 7161 ko04340 Hedgehog signaling pathway 0.999999999983276 -1.6724405587763e-11 47 0 0 26 7161 hsa04672 Intestinal immune network for IgA production 0.999999999983276 -1.6724405587763e-11 47 0 0 26 7161 ko04672 Intestinal immune network for IgA production 0.999999999983276 -1.6724405587763e-11 47 0 0 26 7161 ko00600 Sphingolipid metabolism 0.999999999983276 -1.6724405587763e-11 47 0 0 26 7161 hsa03420 Nucleotide excision repair 0.999999999983276 -1.6724405587763e-11 47 0 0 26 7161 ko03420 Nucleotide excision repair 0.999999999983276 -1.6724405587763e-11 47 0 0 26 7161 hsa04340 Hedgehog signaling pathway 0.999999999983276 -1.6724405587763e-11 47 0 0 26 7161 hsa00600 Sphingolipid metabolism 0.999999999983276 -1.6724405587763e-11 47 0 0 26 7161 hsa00410 beta-Alanine metabolism 0.999999999983322 -1.66781556821694e-11 31 0 0 26 7161 ko03020 RNA polymerase 0.999999999983322 -1.66781556821694e-11 31 0 0 26 7161 hsa00512 Mucin type O-glycan biosynthesis 0.999999999983322 -1.66781556821694e-11 31 0 0 26 7161 ko00410 beta-Alanine metabolism 0.999999999983322 -1.66781556821694e-11 31 0 0 26 7161 ko00512 Mucin type O-glycan biosynthesis 0.999999999983322 -1.66781556821694e-11 31 0 0 26 7161 ko01523 Antifolate resistance 0.999999999983322 -1.66781556821694e-11 31 0 0 26 7161 ko00052 Galactose metabolism 0.999999999983322 -1.66781556821694e-11 31 0 0 26 7161 hsa03020 RNA polymerase 0.999999999983322 -1.66781556821694e-11 31 0 0 26 7161 hsa01523 Antifolate resistance 0.999999999983322 -1.66781556821694e-11 31 0 0 26 7161 hsa00052 Galactose metabolism 0.999999999983322 -1.66781556821694e-11 31 0 0 26 7161 ko00280 Valine, leucine and isoleucine degradation 0.999999999983334 -1.66664595459452e-11 48 0 0 26 7161 hsa00520 Amino sugar and nucleotide sugar metabolism 0.999999999983334 -1.66664595459452e-11 48 0 0 26 7161 hsa04330 Notch signaling pathway 0.999999999983334 -1.66664595459452e-11 48 0 0 26 7161 hsa00280 Valine, leucine and isoleucine degradation 0.999999999983334 -1.66664595459452e-11 48 0 0 26 7161 ko00520 Amino sugar and nucleotide sugar metabolism 0.999999999983334 -1.66664595459452e-11 48 0 0 26 7161 ko04330 Notch signaling pathway 0.999999999983334 -1.66664595459452e-11 48 0 0 26 7161 hsa01212 Fatty acid metabolism 0.999999999983334 -1.66664595459452e-11 48 0 0 26 7161 ko01212 Fatty acid metabolism 0.999999999983334 -1.66664595459452e-11 48 0 0 26 7161 hsa03060 Protein export 0.999999999983891 -1.61086914427206e-11 23 0 0 26 7161 hsa04614 Renin-angiotensin system 0.999999999983891 -1.61086914427206e-11 23 0 0 26 7161 ko00515 Mannose type O-glycan biosynthesis 0.999999999983891 -1.61086914427206e-11 23 0 0 26 7161 hsa03430 Mismatch repair 0.999999999983891 -1.61086914427206e-11 23 0 0 26 7161 hsa01040 Biosynthesis of unsaturated fatty acids 0.999999999983891 -1.61086914427206e-11 23 0 0 26 7161 ko03430 Mismatch repair 0.999999999983891 -1.61086914427206e-11 23 0 0 26 7161 hsa00515 Mannose type O-glycan biosynthesis 0.999999999983891 -1.61086914427206e-11 23 0 0 26 7161 ko01040 Biosynthesis of unsaturated fatty acids 0.999999999983891 -1.61086914427206e-11 23 0 0 26 7161 ko03060 Protein export 0.999999999983891 -1.61086914427206e-11 23 0 0 26 7161 ko04614 Renin-angiotensin system 0.999999999983891 -1.61086914427206e-11 23 0 0 26 7161 ko04136 Autophagy - other 0.999999999984543 -1.5456553393225e-11 32 0 0 26 7161 hsa04136 Autophagy - other 0.999999999984543 -1.5456553393225e-11 32 0 0 26 7161 ko00640 Propanoate metabolism 0.999999999984543 -1.5456553393225e-11 32 0 0 26 7161 hsa00640 Propanoate metabolism 0.999999999984543 -1.5456553393225e-11 32 0 0 26 7161 hsa_M00682 Notch signaling 0.999999999984627 -1.53734291734162e-11 16 0 0 26 7161 M00682 Notch signaling 0.999999999984627 -1.53734291734162e-11 16 0 0 26 7161 M00683 Hippo signaling 0.999999999984627 -1.53734291734162e-11 16 0 0 26 7161 M00099 Sphingosine biosynthesis 0.999999999984627 -1.53734291734162e-11 16 0 0 26 7161 M00295 BRCA1-associated genome surveillance complex (BASC) 0.999999999984627 -1.53734291734162e-11 16 0 0 26 7161 hsa_M00683 Hippo signaling 0.999999999984627 -1.53734291734162e-11 16 0 0 26 7161 hsa_M00099 Sphingosine biosynthesis 0.999999999984627 -1.53734291734162e-11 16 0 0 26 7161 hsa_M00295 BRCA1-associated genome surveillance complex (BASC) 0.999999999984627 -1.53734291734162e-11 16 0 0 26 7161 hsa_M00684 JAK-STAT signaling 0.99999999998478 -1.52197223429334e-11 19 0 0 26 7161 M00341 Proteasome, 19S regulatory particle (PA700) 0.99999999998478 -1.52197223429334e-11 19 0 0 26 7161 M00684 JAK-STAT signaling 0.99999999998478 -1.52197223429334e-11 19 0 0 26 7161 hsa_M00341 Proteasome, 19S regulatory particle (PA700) 0.99999999998478 -1.52197223429334e-11 19 0 0 26 7161 hsa_M00677 Wnt signaling 0.999999999984796 -1.52035294272904e-11 38 0 0 26 7161 M00677 Wnt signaling 0.999999999984796 -1.52035294272904e-11 38 0 0 26 7161 hsa_M00359 Aminoacyl-tRNA biosynthesis, eukaryotes 0.999999999984796 -1.52035294272904e-11 38 0 0 26 7161 M00359 Aminoacyl-tRNA biosynthesis, eukaryotes 0.999999999984796 -1.52035294272904e-11 38 0 0 26 7161 M00069 Glycosphingolipid biosynthesis, ganglio series, LacCer => GT3 0.999999999985306 -1.46942357008065e-11 3 0 0 26 7161 hsa_M00100 Sphingosine degradation 0.999999999985306 -1.46942357008065e-11 3 0 0 26 7161 M00297 DNA-PK complex 0.999999999985306 -1.46942357008065e-11 3 0 0 26 7161 M00392 Ski complex 0.999999999985306 -1.46942357008065e-11 3 0 0 26 7161 ko00780 Biotin metabolism 0.999999999985306 -1.46942357008065e-11 3 0 0 26 7161 hsa_M00046 Pyrimidine degradation, uracil => beta-alanine, thymine => 3-aminoisobutanoate 0.999999999985306 -1.46942357008065e-11 3 0 0 26 7161 M00291 MRN complex 0.999999999985306 -1.46942357008065e-11 3 0 0 26 7161 hsa_M00408 ESCRT-0 complex 0.999999999985306 -1.46942357008065e-11 3 0 0 26 7161 hsa00785 Lipoic acid metabolism 0.999999999985306 -1.46942357008065e-11 3 0 0 26 7161 hsa_M00118 Glutathione biosynthesis, glutamate => glutathione 0.999999999985306 -1.46942357008065e-11 3 0 0 26 7161 M00100 Sphingosine degradation 0.999999999985306 -1.46942357008065e-11 3 0 0 26 7161 M00108 C21-Steroid hormone biosynthesis, progesterone => corticosterone/aldosterone 0.999999999985306 -1.46942357008065e-11 3 0 0 26 7161 M00051 Uridine monophosphate biosynthesis, glutamine (+ PRPP) => UMP 0.999999999985306 -1.46942357008065e-11 3 0 0 26 7161 ko00785 Lipoic acid metabolism 0.999999999985306 -1.46942357008065e-11 3 0 0 26 7161 hsa_M00400 p97-Ufd1-Npl4 complex 0.999999999985306 -1.46942357008065e-11 3 0 0 26 7161 M00118 Glutathione biosynthesis, glutamate => glutathione 0.999999999985306 -1.46942357008065e-11 3 0 0 26 7161 M00082 Fatty acid biosynthesis, initiation 0.999999999985306 -1.46942357008065e-11 3 0 0 26 7161 hsa_M00082 Fatty acid biosynthesis, initiation 0.999999999985306 -1.46942357008065e-11 3 0 0 26 7161 hsa_M00410 ESCRT-II complex 0.999999999985306 -1.46942357008065e-11 3 0 0 26 7161 M00134 Polyamine biosynthesis, arginine => ornithine => putrescine 0.999999999985306 -1.46942357008065e-11 3 0 0 26 7161 M00005 PRPP biosynthesis, ribose 5P => PRPP 0.999999999985306 -1.46942357008065e-11 3 0 0 26 7161 hsa_M00107 Steroid hormone biosynthesis, cholesterol => prognenolone => progesterone 0.999999999985306 -1.46942357008065e-11 3 0 0 26 7161 hsa_M00108 C21-Steroid hormone biosynthesis, progesterone => corticosterone/aldosterone 0.999999999985306 -1.46942357008065e-11 3 0 0 26 7161 hsa_M00297 DNA-PK complex 0.999999999985306 -1.46942357008065e-11 3 0 0 26 7161 hsa00780 Biotin metabolism 0.999999999985306 -1.46942357008065e-11 3 0 0 26 7161 M00410 ESCRT-II complex 0.999999999985306 -1.46942357008065e-11 3 0 0 26 7161 M00046 Pyrimidine degradation, uracil => beta-alanine, thymine => 3-aminoisobutanoate 0.999999999985306 -1.46942357008065e-11 3 0 0 26 7161 M00408 ESCRT-0 complex 0.999999999985306 -1.46942357008065e-11 3 0 0 26 7161 M00400 p97-Ufd1-Npl4 complex 0.999999999985306 -1.46942357008065e-11 3 0 0 26 7161 hsa_M00051 Uridine monophosphate biosynthesis, glutamine (+ PRPP) => UMP 0.999999999985306 -1.46942357008065e-11 3 0 0 26 7161 hsa_M00392 Ski complex 0.999999999985306 -1.46942357008065e-11 3 0 0 26 7161 hsa_M00020 Serine biosynthesis, glycerate-3P => serine 0.999999999985306 -1.46942357008065e-11 3 0 0 26 7161 M00020 Serine biosynthesis, glycerate-3P => serine 0.999999999985306 -1.46942357008065e-11 3 0 0 26 7161 hsa_M00005 PRPP biosynthesis, ribose 5P => PRPP 0.999999999985306 -1.46942357008065e-11 3 0 0 26 7161 M00132 Inositol phosphate metabolism, Ins(1,3,4)P3 => phytate 0.999999999985306 -1.46942357008065e-11 3 0 0 26 7161 M00107 Steroid hormone biosynthesis, cholesterol => prognenolone => progesterone 0.999999999985306 -1.46942357008065e-11 3 0 0 26 7161 hsa_M00134 Polyamine biosynthesis, arginine => ornithine => putrescine 0.999999999985306 -1.46942357008065e-11 3 0 0 26 7161 hsa_M00069 Glycosphingolipid biosynthesis, ganglio series, LacCer => GT3 0.999999999985306 -1.46942357008065e-11 3 0 0 26 7161 hsa_M00291 MRN complex 0.999999999985306 -1.46942357008065e-11 3 0 0 26 7161 hsa_M00132 Inositol phosphate metabolism, Ins(1,3,4)P3 => phytate 0.999999999985306 -1.46942357008065e-11 3 0 0 26 7161 ko04130 SNARE interactions in vesicular transport 0.999999999986334 -1.36659792636647e-11 34 0 0 26 7161 ko00040 Pentose and glucuronate interconversions 0.999999999986334 -1.36659792636647e-11 34 0 0 26 7161 hsa04130 SNARE interactions in vesicular transport 0.999999999986334 -1.36659792636647e-11 34 0 0 26 7161 hsa00040 Pentose and glucuronate interconversions 0.999999999986334 -1.36659792636647e-11 34 0 0 26 7161 ko05031 Amphetamine addiction 0.999999999986627 -1.33732241049548e-11 68 0 0 26 7161 hsa05031 Amphetamine addiction 0.999999999986627 -1.33732241049548e-11 68 0 0 26 7161 ko04142 Lysosome 0.999999999986813 -1.31868895624625e-11 123 0 0 26 7161 hsa04142 Lysosome 0.999999999986813 -1.31868895624625e-11 123 0 0 26 7161 hsa05134 Legionellosis 0.999999999987418 -1.25817125924612e-11 55 0 0 26 7161 ko05221 Acute myeloid leukemia 0.999999999987418 -1.25817125924612e-11 55 0 0 26 7161 ko05134 Legionellosis 0.999999999987418 -1.25817125924612e-11 55 0 0 26 7161 hsa05221 Acute myeloid leukemia 0.999999999987418 -1.25817125924612e-11 55 0 0 26 7161 ko05130 Pathogenic Escherichia coli infection 0.999999999987418 -1.25817125924612e-11 55 0 0 26 7161 ko05217 Basal cell carcinoma 0.999999999987418 -1.25817125924612e-11 55 0 0 26 7161 hsa05150 Staphylococcus aureus infection 0.999999999987418 -1.25817125924612e-11 55 0 0 26 7161 hsa05130 Pathogenic Escherichia coli infection 0.999999999987418 -1.25817125924612e-11 55 0 0 26 7161 ko05150 Staphylococcus aureus infection 0.999999999987418 -1.25817125924612e-11 55 0 0 26 7161 hsa05217 Basal cell carcinoma 0.999999999987418 -1.25817125924612e-11 55 0 0 26 7161 ko05230 Central carbon metabolism in cancer 0.999999999987538 -1.2461595322083e-11 65 0 0 26 7161 hsa00830 Retinol metabolism 0.999999999987538 -1.2461595322083e-11 65 0 0 26 7161 ko00830 Retinol metabolism 0.999999999987538 -1.2461595322083e-11 65 0 0 26 7161 hsa05230 Central carbon metabolism in cancer 0.999999999987538 -1.2461595322083e-11 65 0 0 26 7161 hsa00250 Alanine, aspartate and glutamate metabolism 0.99999999998843 -1.1569758232109e-11 35 0 0 26 7161 hsa05020 Prion diseases 0.99999999998843 -1.1569758232109e-11 35 0 0 26 7161 ko00250 Alanine, aspartate and glutamate metabolism 0.99999999998843 -1.1569758232109e-11 35 0 0 26 7161 ko05020 Prion diseases 0.99999999998843 -1.1569758232109e-11 35 0 0 26 7161 hsa00350 Tyrosine metabolism 0.99999999998843 -1.1569758232109e-11 35 0 0 26 7161 ko00350 Tyrosine metabolism 0.99999999998843 -1.1569758232109e-11 35 0 0 26 7161 hsa04110 Cell cycle 0.999999999988477 -1.15230330204922e-11 124 0 0 26 7161 ko04110 Cell cycle 0.999999999988477 -1.15230330204922e-11 124 0 0 26 7161 ko05110 Vibrio cholerae infection 0.999999999988586 -1.14135087708834e-11 51 0 0 26 7161 hsa05110 Vibrio cholerae infection 0.999999999988586 -1.14135087708834e-11 51 0 0 26 7161 ko03030 DNA replication 0.999999999988839 -1.11611419907899e-11 36 0 0 26 7161 ko00500 Starch and sucrose metabolism 0.999999999988839 -1.11611419907899e-11 36 0 0 26 7161 hsa05340 Primary immunodeficiency 0.999999999988839 -1.11611419907899e-11 36 0 0 26 7161 hsa03030 DNA replication 0.999999999988839 -1.11611419907899e-11 36 0 0 26 7161 ko05340 Primary immunodeficiency 0.999999999988839 -1.11611419907899e-11 36 0 0 26 7161 hsa00500 Starch and sucrose metabolism 0.999999999988839 -1.11611419907899e-11 36 0 0 26 7161 hsa_M00679 BMP signaling 0.999999999988982 -1.10180870505943e-11 20 0 0 26 7161 ko00670 One carbon pool by folate 0.999999999988982 -1.10180870505943e-11 20 0 0 26 7161 M00352 Spliceosome, U2-snRNP 0.999999999988982 -1.10180870505943e-11 20 0 0 26 7161 hsa00100 Steroid biosynthesis 0.999999999988982 -1.10180870505943e-11 20 0 0 26 7161 hsa00670 One carbon pool by folate 0.999999999988982 -1.10180870505943e-11 20 0 0 26 7161 hsa_M00352 Spliceosome, U2-snRNP 0.999999999988982 -1.10180870505943e-11 20 0 0 26 7161 M00679 BMP signaling 0.999999999988982 -1.10180870505943e-11 20 0 0 26 7161 ko00100 Steroid biosynthesis 0.999999999988982 -1.10180870505943e-11 20 0 0 26 7161 hsa00532 Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate 0.999999999988982 -1.10180870505943e-11 20 0 0 26 7161 ko00532 Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate 0.999999999988982 -1.10180870505943e-11 20 0 0 26 7161 ko05330 Allograft rejection 0.999999999989309 -1.06911218283265e-11 37 0 0 26 7161 hsa_M00355 Spliceosome, 35S U5-snRNP 0.999999999989309 -1.06911218283265e-11 37 0 0 26 7161 hsa05330 Allograft rejection 0.999999999989309 -1.06911218283265e-11 37 0 0 26 7161 M00355 Spliceosome, 35S U5-snRNP 0.999999999989309 -1.06911218283265e-11 37 0 0 26 7161 hsa00480 Glutathione metabolism 0.999999999989778 -1.02217045724327e-11 54 0 0 26 7161 ko00480 Glutathione metabolism 0.999999999989778 -1.02217045724327e-11 54 0 0 26 7161 ko03460 Fanconi anemia pathway 0.999999999989778 -1.02217045724327e-11 54 0 0 26 7161 hsa03460 Fanconi anemia pathway 0.999999999989778 -1.02217045724327e-11 54 0 0 26 7161 ko00564 Glycerophospholipid metabolism 0.999999999989906 -1.0094150236779e-11 95 0 0 26 7161 hsa00564 Glycerophospholipid metabolism 0.999999999989906 -1.0094150236779e-11 95 0 0 26 7161 M00072 N-glycosylation by oligosaccharyltransferase 0.999999999990083 -9.9166699097733e-12 7 0 0 26 7161 M00397 Lsm 1-7 complex 0.999999999990083 -9.9166699097733e-12 7 0 0 26 7161 hsa_M00072 N-glycosylation by oligosaccharyltransferase 0.999999999990083 -9.9166699097733e-12 7 0 0 26 7161 M00092 Phosphatidylethanolamine (PE) biosynthesis, ethanolamine => PE 0.999999999990083 -9.9166699097733e-12 7 0 0 26 7161 hsa_M00396 Lsm 2-8 complex 0.999999999990083 -9.9166699097733e-12 7 0 0 26 7161 hsa_M00549 Nucleotide sugar biosynthesis, glucose => UDP-glucose 0.999999999990083 -9.9166699097733e-12 7 0 0 26 7161 M00047 Creatine pathway 0.999999999990083 -9.9166699097733e-12 7 0 0 26 7161 M00691 DNA damage-induced cell cycle checkpoints 0.999999999990083 -9.9166699097733e-12 7 0 0 26 7161 hsa_M00120 Coenzyme A biosynthesis, pantothenate => CoA 0.999999999990083 -9.9166699097733e-12 7 0 0 26 7161 hsa_M00397 Lsm 1-7 complex 0.999999999990083 -9.9166699097733e-12 7 0 0 26 7161 M00398 Sm core complex 0.999999999990083 -9.9166699097733e-12 7 0 0 26 7161 M00120 Coenzyme A biosynthesis, pantothenate => CoA 0.999999999990083 -9.9166699097733e-12 7 0 0 26 7161 hsa_M00398 Sm core complex 0.999999999990083 -9.9166699097733e-12 7 0 0 26 7161 hsa_M00007 Pentose phosphate pathway, non-oxidative phase, fructose 6P => ribose 5P 0.999999999990083 -9.9166699097733e-12 7 0 0 26 7161 M00396 Lsm 2-8 complex 0.999999999990083 -9.9166699097733e-12 7 0 0 26 7161 hsa_M00047 Creatine pathway 0.999999999990083 -9.9166699097733e-12 7 0 0 26 7161 hsa_M00086 beta-Oxidation, acyl-CoA synthesis 0.999999999990083 -9.9166699097733e-12 7 0 0 26 7161 hsa_M00092 Phosphatidylethanolamine (PE) biosynthesis, ethanolamine => PE 0.999999999990083 -9.9166699097733e-12 7 0 0 26 7161 M00086 beta-Oxidation, acyl-CoA synthesis 0.999999999990083 -9.9166699097733e-12 7 0 0 26 7161 M00007 Pentose phosphate pathway, non-oxidative phase, fructose 6P => ribose 5P 0.999999999990083 -9.9166699097733e-12 7 0 0 26 7161 M00549 Nucleotide sugar biosynthesis, glucose => UDP-glucose 0.999999999990083 -9.9166699097733e-12 7 0 0 26 7161 hsa_M00691 DNA damage-induced cell cycle checkpoints 0.999999999990083 -9.9166699097733e-12 7 0 0 26 7161 ko04350 TGF-beta signaling pathway 0.999999999990205 -9.79500112410425e-12 84 0 0 26 7161 ko05222 Small cell lung cancer 0.999999999990205 -9.79500112410425e-12 84 0 0 26 7161 hsa04350 TGF-beta signaling pathway 0.999999999990205 -9.79500112410425e-12 84 0 0 26 7161 hsa05222 Small cell lung cancer 0.999999999990205 -9.79500112410425e-12 84 0 0 26 7161 hsa00010 Glycolysis / Gluconeogenesis 0.999999999990214 -9.78552603082671e-12 67 0 0 26 7161 ko00010 Glycolysis / Gluconeogenesis 0.999999999990214 -9.78552603082671e-12 67 0 0 26 7161 ko05202 Transcriptional misregulation in cancer 0.99999999999096 -9.04046321251569e-12 179 0 0 26 7161 hsa05202 Transcriptional misregulation in cancer 0.99999999999096 -9.04046321251569e-12 179 0 0 26 7161 ko00240 Pyrimidine metabolism 0.999999999991056 -8.9434756769313e-12 104 0 0 26 7161 hsa00240 Pyrimidine metabolism 0.999999999991056 -8.9434756769313e-12 104 0 0 26 7161 hsa_M00160 V-type ATPase, eukaryotes 0.999999999991294 -8.70601559300829e-12 24 0 0 26 7161 ko04977 Vitamin digestion and absorption 0.999999999991294 -8.70601559300829e-12 24 0 0 26 7161 M00160 V-type ATPase, eukaryotes 0.999999999991294 -8.70601559300829e-12 24 0 0 26 7161 hsa00534 Glycosaminoglycan biosynthesis - heparan sulfate / heparin 0.999999999991294 -8.70601559300829e-12 24 0 0 26 7161 hsa00340 Histidine metabolism 0.999999999991294 -8.70601559300829e-12 24 0 0 26 7161 ko00534 Glycosaminoglycan biosynthesis - heparan sulfate / heparin 0.999999999991294 -8.70601559300829e-12 24 0 0 26 7161 hsa04977 Vitamin digestion and absorption 0.999999999991294 -8.70601559300829e-12 24 0 0 26 7161 ko00340 Histidine metabolism 0.999999999991294 -8.70601559300829e-12 24 0 0 26 7161 hsa04640 Hematopoietic cell lineage 0.999999999992119 -7.88124879226597e-12 96 0 0 26 7161 ko04640 Hematopoietic cell lineage 0.999999999992119 -7.88124879226597e-12 96 0 0 26 7161 ko05320 Autoimmune thyroid disease 0.999999999992329 -7.67121829746706e-12 52 0 0 26 7161 hsa05320 Autoimmune thyroid disease 0.999999999992329 -7.67121829746706e-12 52 0 0 26 7161 hsa_M00043 Thyroid hormone biosynthesis, tyrosine => triiodothyronine/thyroxine 0.999999999992516 -7.48383863560798e-12 1 0 0 26 7161 M00091 Phosphatidylcholine (PC) biosynthesis, PE => PC 0.999999999992516 -7.48383863560798e-12 1 0 0 26 7161 M00043 Thyroid hormone biosynthesis, tyrosine => triiodothyronine/thyroxine 0.999999999992516 -7.48383863560798e-12 1 0 0 26 7161 hsa_M00091 Phosphatidylcholine (PC) biosynthesis, PE => PC 0.999999999992516 -7.48383863560798e-12 1 0 0 26 7161 hsa00472 D-Arginine and D-ornithine metabolism 0.999999999992516 -7.48383863560798e-12 1 0 0 26 7161 ko00472 D-Arginine and D-ornithine metabolism 0.999999999992516 -7.48383863560798e-12 1 0 0 26 7161 ko04150 mTOR signaling pathway 0.999999999992904 -7.09618188490152e-12 150 0 0 26 7161 hsa04150 mTOR signaling pathway 0.999999999992904 -7.09618188490152e-12 150 0 0 26 7161 ko05140 Leishmaniasis 0.999999999993215 -6.7854681260797e-12 72 0 0 26 7161 hsa05140 Leishmaniasis 0.999999999993215 -6.7854681260797e-12 72 0 0 26 7161 hsa00300 Lysine biosynthesis 0.999999999993286 -6.71399337662866e-12 2 0 0 26 7161 M00066 Lactosylceramide biosynthesis 0.999999999993286 -6.71399337662866e-12 2 0 0 26 7161 M00083 Fatty acid biosynthesis, elongation 0.999999999993286 -6.71399337662866e-12 2 0 0 26 7161 hsa_M00293 DNA polymerase zeta complex 0.999999999993286 -6.71399337662866e-12 2 0 0 26 7161 M00068 Glycosphingolipid biosynthesis, globo-series, LacCer => Gb4Cer 0.999999999993286 -6.71399337662866e-12 2 0 0 26 7161 hsa_M00554 Nucleotide sugar biosynthesis, galactose => UDP-galactose 0.999999999993286 -6.71399337662866e-12 2 0 0 26 7161 hsa_M00066 Lactosylceramide biosynthesis 0.999999999993286 -6.71399337662866e-12 2 0 0 26 7161 M00293 DNA polymerase zeta complex 0.999999999993286 -6.71399337662866e-12 2 0 0 26 7161 hsa_M00338 Cysteine biosynthesis, homocysteine + serine => cysteine 0.999999999993286 -6.71399337662866e-12 2 0 0 26 7161 M00151 Cytochrome bc1 complex respiratory unit 0.999999999993286 -6.71399337662866e-12 2 0 0 26 7161 M00338 Cysteine biosynthesis, homocysteine + serine => cysteine 0.999999999993286 -6.71399337662866e-12 2 0 0 26 7161 M00106 Conjugated bile acid biosynthesis, cholate => taurocholate/glycocholate 0.999999999993286 -6.71399337662866e-12 2 0 0 26 7161 hsa_M00151 Cytochrome bc1 complex respiratory unit 0.999999999993286 -6.71399337662866e-12 2 0 0 26 7161 M00103 Cholecalciferol biosynthesis 0.999999999993286 -6.71399337662866e-12 2 0 0 26 7161 M00554 Nucleotide sugar biosynthesis, galactose => UDP-galactose 0.999999999993286 -6.71399337662866e-12 2 0 0 26 7161 M00294 DNA polymerase gamma complex 0.999999999993286 -6.71399337662866e-12 2 0 0 26 7161 M00067 Sulfoglycolipids biosynthesis, ceramide/1-alkyl-2-acylglycerol => sulfatide/seminolipid 0.999999999993286 -6.71399337662866e-12 2 0 0 26 7161 hsa_M00294 DNA polymerase gamma complex 0.999999999993286 -6.71399337662866e-12 2 0 0 26 7161 M00399 Cap binding complex 0.999999999993286 -6.71399337662866e-12 2 0 0 26 7161 hsa_M00068 Glycosphingolipid biosynthesis, globo-series, LacCer => Gb4Cer 0.999999999993286 -6.71399337662866e-12 2 0 0 26 7161 hsa_M00067 Sulfoglycolipids biosynthesis, ceramide/1-alkyl-2-acylglycerol => sulfatide/seminolipid 0.999999999993286 -6.71399337662866e-12 2 0 0 26 7161 ko00300 Lysine biosynthesis 0.999999999993286 -6.71399337662866e-12 2 0 0 26 7161 hsa_M00399 Cap binding complex 0.999999999993286 -6.71399337662866e-12 2 0 0 26 7161 hsa_M00103 Cholecalciferol biosynthesis 0.999999999993286 -6.71399337662866e-12 2 0 0 26 7161 hsa_M00106 Conjugated bile acid biosynthesis, cholate => taurocholate/glycocholate 0.999999999993286 -6.71399337662866e-12 2 0 0 26 7161 hsa_M00083 Fatty acid biosynthesis, elongation 0.999999999993286 -6.71399337662866e-12 2 0 0 26 7161 ko00511 Other glycan degradation 0.999999999993342 -6.65800202599061e-12 18 0 0 26 7161 hsa00770 Pantothenate and CoA biosynthesis 0.999999999993342 -6.65800202599061e-12 18 0 0 26 7161 M00430 Exon junction complex (EJC) 0.999999999993342 -6.65800202599061e-12 18 0 0 26 7161 hsa01210 2-Oxocarboxylic acid metabolism 0.999999999993342 -6.65800202599061e-12 18 0 0 26 7161 ko00770 Pantothenate and CoA biosynthesis 0.999999999993342 -6.65800202599061e-12 18 0 0 26 7161 ko01210 2-Oxocarboxylic acid metabolism 0.999999999993342 -6.65800202599061e-12 18 0 0 26 7161 hsa00511 Other glycan degradation 0.999999999993342 -6.65800202599061e-12 18 0 0 26 7161 hsa_M00430 Exon junction complex (EJC) 0.999999999993342 -6.65800202599061e-12 18 0 0 26 7161 hsa00290 Valine, leucine and isoleucine biosynthesis 0.99999999999373 -6.26962861865623e-12 4 0 0 26 7161 hsa_M00402 Translocon-associated protein (TRAP) complex 0.99999999999373 -6.26962861865623e-12 4 0 0 26 7161 M00402 Translocon-associated protein (TRAP) complex 0.99999999999373 -6.26962861865623e-12 4 0 0 26 7161 hsa_M00384 Cul3-SPOP complex 0.99999999999373 -6.26962861865623e-12 4 0 0 26 7161 ko00290 Valine, leucine and isoleucine biosynthesis 0.99999999999373 -6.26962861865623e-12 4 0 0 26 7161 M00401 Sec61 complex 0.99999999999373 -6.26962861865623e-12 4 0 0 26 7161 hsa_M00288 RPA complex 0.99999999999373 -6.26962861865623e-12 4 0 0 26 7161 hsa_M00387 SCF-FBW7 complex 0.99999999999373 -6.26962861865623e-12 4 0 0 26 7161 hsa_M00425 H/ACA ribonucleoprotein complex 0.99999999999373 -6.26962861865623e-12 4 0 0 26 7161 hsa_M00393 TRAMP complex 0.99999999999373 -6.26962861865623e-12 4 0 0 26 7161 hsa_M00741 Propanoyl-CoA metabolism, propanoyl-CoA => succinyl-CoA 0.99999999999373 -6.26962861865623e-12 4 0 0 26 7161 hsa_M00110 C19/C18-Steroid hormone biosynthesis, pregnenolone => androstenedione => estrone 0.99999999999373 -6.26962861865623e-12 4 0 0 26 7161 M00027 GABA (gamma-Aminobutyrate) shunt 0.99999999999373 -6.26962861865623e-12 4 0 0 26 7161 hsa_M00006 Pentose phosphate pathway, oxidative phase, glucose 6P => ribulose 5P 0.99999999999373 -6.26962861865623e-12 4 0 0 26 7161 M00006 Pentose phosphate pathway, oxidative phase, glucose 6P => ribulose 5P 0.99999999999373 -6.26962861865623e-12 4 0 0 26 7161 hsa_M00632 Galactose degradation, Leloir pathway, galactose => alpha-D-glucose-1P 0.99999999999373 -6.26962861865623e-12 4 0 0 26 7161 M00015 Proline biosynthesis, glutamate => proline 0.99999999999373 -6.26962861865623e-12 4 0 0 26 7161 hsa_M00401 Sec61 complex 0.99999999999373 -6.26962861865623e-12 4 0 0 26 7161 M00393 TRAMP complex 0.99999999999373 -6.26962861865623e-12 4 0 0 26 7161 hsa_M00070 Glycosphingolipid biosynthesis, lacto-series, LacCer => Lc4Cer 0.99999999999373 -6.26962861865623e-12 4 0 0 26 7161 M00381 SCF-SKP2 complex 0.99999999999373 -6.26962861865623e-12 4 0 0 26 7161 hsa_M00685 Apoptotic machinery 0.99999999999373 -6.26962861865623e-12 4 0 0 26 7161 hsa_M00381 SCF-SKP2 complex 0.99999999999373 -6.26962861865623e-12 4 0 0 26 7161 hsa00471 D-Glutamine and D-glutamate metabolism 0.99999999999373 -6.26962861865623e-12 4 0 0 26 7161 M00110 C19/C18-Steroid hormone biosynthesis, pregnenolone => androstenedione => estrone 0.99999999999373 -6.26962861865623e-12 4 0 0 26 7161 hsa_M00133 Polyamine biosynthesis, arginine => agmatine => putrescine => spermidine 0.99999999999373 -6.26962861865623e-12 4 0 0 26 7161 hsa_M00263 DNA polymerase epsilon complex 0.99999999999373 -6.26962861865623e-12 4 0 0 26 7161 hsa_M00148 Succinate dehydrogenase (ubiquinone) 0.99999999999373 -6.26962861865623e-12 4 0 0 26 7161 M00387 SCF-FBW7 complex 0.99999999999373 -6.26962861865623e-12 4 0 0 26 7161 M00425 H/ACA ribonucleoprotein complex 0.99999999999373 -6.26962861865623e-12 4 0 0 26 7161 ko00471 D-Glutamine and D-glutamate metabolism 0.99999999999373 -6.26962861865623e-12 4 0 0 26 7161 M00390 Exosome, archaea 0.99999999999373 -6.26962861865623e-12 4 0 0 26 7161 M00685 Apoptotic machinery 0.99999999999373 -6.26962861865623e-12 4 0 0 26 7161 M00148 Succinate dehydrogenase (ubiquinone) 0.99999999999373 -6.26962861865623e-12 4 0 0 26 7161 M00261 DNA polymerase alpha / primase complex 0.99999999999373 -6.26962861865623e-12 4 0 0 26 7161 M00070 Glycosphingolipid biosynthesis, lacto-series, LacCer => Lc4Cer 0.99999999999373 -6.26962861865623e-12 4 0 0 26 7161 M00133 Polyamine biosynthesis, arginine => agmatine => putrescine => spermidine 0.99999999999373 -6.26962861865623e-12 4 0 0 26 7161 M00262 DNA polymerase delta complex 0.99999999999373 -6.26962861865623e-12 4 0 0 26 7161 M00632 Galactose degradation, Leloir pathway, galactose => alpha-D-glucose-1P 0.99999999999373 -6.26962861865623e-12 4 0 0 26 7161 hsa_M00261 DNA polymerase alpha / primase complex 0.99999999999373 -6.26962861865623e-12 4 0 0 26 7161 hsa_M00286 GINS complex 0.99999999999373 -6.26962861865623e-12 4 0 0 26 7161 M00741 Propanoyl-CoA metabolism, propanoyl-CoA => succinyl-CoA 0.99999999999373 -6.26962861865623e-12 4 0 0 26 7161 M00263 DNA polymerase epsilon complex 0.99999999999373 -6.26962861865623e-12 4 0 0 26 7161 M00286 GINS complex 0.99999999999373 -6.26962861865623e-12 4 0 0 26 7161 hsa_M00027 GABA (gamma-Aminobutyrate) shunt 0.99999999999373 -6.26962861865623e-12 4 0 0 26 7161 hsa_M00390 Exosome, archaea 0.99999999999373 -6.26962861865623e-12 4 0 0 26 7161 M00384 Cul3-SPOP complex 0.99999999999373 -6.26962861865623e-12 4 0 0 26 7161 M00288 RPA complex 0.99999999999373 -6.26962861865623e-12 4 0 0 26 7161 hsa_M00690 MAPK (ERK5) signaling 0.99999999999373 -6.26962861865623e-12 4 0 0 26 7161 M00690 MAPK (ERK5) signaling 0.99999999999373 -6.26962861865623e-12 4 0 0 26 7161 hsa_M00015 Proline biosynthesis, glutamate => proline 0.99999999999373 -6.26962861865623e-12 4 0 0 26 7161 hsa_M00262 DNA polymerase delta complex 0.99999999999373 -6.26962861865623e-12 4 0 0 26 7161 ko00620 Pyruvate metabolism 0.999999999993871 -6.1293815478971e-12 39 0 0 26 7161 ko00260 Glycine, serine and threonine metabolism 0.999999999993871 -6.1293815478971e-12 39 0 0 26 7161 hsa00620 Pyruvate metabolism 0.999999999993871 -6.1293815478971e-12 39 0 0 26 7161 hsa00260 Glycine, serine and threonine metabolism 0.999999999993871 -6.1293815478971e-12 39 0 0 26 7161 ko04662 B cell receptor signaling pathway 0.999999999993989 -6.01053435513002e-12 70 0 0 26 7161 hsa04662 B cell receptor signaling pathway 0.999999999993989 -6.01053435513002e-12 70 0 0 26 7161 hsa05012 Parkinson's disease 0.999999999994074 -5.92565556877247e-12 129 0 0 26 7161 ko00790 Folate biosynthesis 0.999999999994103 -5.89714039159796e-12 15 0 0 26 7161 hsa_M00158 F-type ATPase, eukaryotes 0.999999999994103 -5.89714039159796e-12 15 0 0 26 7161 hsa00730 Thiamine metabolism 0.999999999994103 -5.89714039159796e-12 15 0 0 26 7161 hsa00790 Folate biosynthesis 0.999999999994103 -5.89714039159796e-12 15 0 0 26 7161 hsa00604 Glycosphingolipid biosynthesis - ganglio series 0.999999999994103 -5.89714039159796e-12 15 0 0 26 7161 ko00604 Glycosphingolipid biosynthesis - ganglio series 0.999999999994103 -5.89714039159796e-12 15 0 0 26 7161 hsa00603 Glycosphingolipid biosynthesis - globo and isoglobo series 0.999999999994103 -5.89714039159796e-12 15 0 0 26 7161 M00340 Proteasome, 20S core particle 0.999999999994103 -5.89714039159796e-12 15 0 0 26 7161 hsa_M00686 Toll-like receptor signaling 0.999999999994103 -5.89714039159796e-12 15 0 0 26 7161 hsa_M00340 Proteasome, 20S core particle 0.999999999994103 -5.89714039159796e-12 15 0 0 26 7161 M00146 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex 0.999999999994103 -5.89714039159796e-12 15 0 0 26 7161 M00686 Toll-like receptor signaling 0.999999999994103 -5.89714039159796e-12 15 0 0 26 7161 M00158 F-type ATPase, eukaryotes 0.999999999994103 -5.89714039159796e-12 15 0 0 26 7161 ko00730 Thiamine metabolism 0.999999999994103 -5.89714039159796e-12 15 0 0 26 7161 hsa_M00146 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex 0.999999999994103 -5.89714039159796e-12 15 0 0 26 7161 ko04660 T cell receptor signaling pathway 0.999999999994333 -5.66669215746169e-12 102 0 0 26 7161 hsa04660 T cell receptor signaling pathway 0.999999999994333 -5.66669215746169e-12 102 0 0 26 7161 hsa_M00003 Gluconeogenesis, oxaloacetate => fructose-6P 0.999999999994451 -5.54882199412653e-12 17 0 0 26 7161 hsa_M00089 Triacylglycerol biosynthesis 0.999999999994451 -5.54882199412653e-12 17 0 0 26 7161 ko00450 Selenocompound metabolism 0.999999999994451 -5.54882199412653e-12 17 0 0 26 7161 hsa00910 Nitrogen metabolism 0.999999999994451 -5.54882199412653e-12 17 0 0 26 7161 hsa00120 Primary bile acid biosynthesis 0.999999999994451 -5.54882199412653e-12 17 0 0 26 7161 M00181 RNA polymerase III, eukaryotes 0.999999999994451 -5.54882199412653e-12 17 0 0 26 7161 hsa_M00337 Immunoproteasome 0.999999999994451 -5.54882199412653e-12 17 0 0 26 7161 ko00120 Primary bile acid biosynthesis 0.999999999994451 -5.54882199412653e-12 17 0 0 26 7161 ko00910 Nitrogen metabolism 0.999999999994451 -5.54882199412653e-12 17 0 0 26 7161 hsa00450 Selenocompound metabolism 0.999999999994451 -5.54882199412653e-12 17 0 0 26 7161 hsa00360 Phenylalanine metabolism 0.999999999994451 -5.54882199412653e-12 17 0 0 26 7161 M00003 Gluconeogenesis, oxaloacetate => fructose-6P 0.999999999994451 -5.54882199412653e-12 17 0 0 26 7161 M00337 Immunoproteasome 0.999999999994451 -5.54882199412653e-12 17 0 0 26 7161 ko00360 Phenylalanine metabolism 0.999999999994451 -5.54882199412653e-12 17 0 0 26 7161 M00089 Triacylglycerol biosynthesis 0.999999999994451 -5.54882199412653e-12 17 0 0 26 7161 hsa_M00181 RNA polymerase III, eukaryotes 0.999999999994451 -5.54882199412653e-12 17 0 0 26 7161 hsa_M00128 Ubiquinone biosynthesis, eukaryotes, 4-hydroxybenzoate => ubiquinone 0.999999999994625 -5.3752713152685e-12 5 0 0 26 7161 M00071 Glycosphingolipid biosynthesis, neolacto-series, LacCer => nLc4Cer 0.999999999994625 -5.3752713152685e-12 5 0 0 26 7161 hsa_M00382 SCF-FBS complex 0.999999999994625 -5.3752713152685e-12 5 0 0 26 7161 hsa00524 Neomycin, kanamycin and gentamicin biosynthesis 0.999999999994625 -5.3752713152685e-12 5 0 0 26 7161 M00042 Catecholamine biosynthesis, tyrosine => dopamine => noradrenaline => adrenaline 0.999999999994625 -5.3752713152685e-12 5 0 0 26 7161 hsa_M00037 Melatonin biosynthesis, tryptophan => serotonin => melatonin 0.999999999994625 -5.3752713152685e-12 5 0 0 26 7161 hsa_M00414 Bloom's syndrome complex 0.999999999994625 -5.3752713152685e-12 5 0 0 26 7161 ko00400 Phenylalanine, tyrosine and tryptophan biosynthesis 0.999999999994625 -5.3752713152685e-12 5 0 0 26 7161 M00383 ECV complex 0.999999999994625 -5.3752713152685e-12 5 0 0 26 7161 hsa_M00071 Glycosphingolipid biosynthesis, neolacto-series, LacCer => nLc4Cer 0.999999999994625 -5.3752713152685e-12 5 0 0 26 7161 hsa00232 Caffeine metabolism 0.999999999994625 -5.3752713152685e-12 5 0 0 26 7161 hsa_M00385 Cul4-DDB1-DDB2 complex 0.999999999994625 -5.3752713152685e-12 5 0 0 26 7161 M00382 SCF-FBS complex 0.999999999994625 -5.3752713152685e-12 5 0 0 26 7161 hsa_M00380 SCF-BTRC complex 0.999999999994625 -5.3752713152685e-12 5 0 0 26 7161 hsa_M00405 THC complex 0.999999999994625 -5.3752713152685e-12 5 0 0 26 7161 hsa_M00289 RF-C complex 0.999999999994625 -5.3752713152685e-12 5 0 0 26 7161 M00057 Glycosaminoglycan biosynthesis, linkage tetrasaccharide 0.999999999994625 -5.3752713152685e-12 5 0 0 26 7161 hsa_M00079 Keratan sulfate degradation 0.999999999994625 -5.3752713152685e-12 5 0 0 26 7161 M00128 Ubiquinone biosynthesis, eukaryotes, 4-hydroxybenzoate => ubiquinone 0.999999999994625 -5.3752713152685e-12 5 0 0 26 7161 hsa_M00042 Catecholamine biosynthesis, tyrosine => dopamine => noradrenaline => adrenaline 0.999999999994625 -5.3752713152685e-12 5 0 0 26 7161 M00079 Keratan sulfate degradation 0.999999999994625 -5.3752713152685e-12 5 0 0 26 7161 hsa_M00383 ECV complex 0.999999999994625 -5.3752713152685e-12 5 0 0 26 7161 hsa_M00044 Tyrosine degradation, tyrosine => homogentisate 0.999999999994625 -5.3752713152685e-12 5 0 0 26 7161 M00414 Bloom's syndrome complex 0.999999999994625 -5.3752713152685e-12 5 0 0 26 7161 ko00232 Caffeine metabolism 0.999999999994625 -5.3752713152685e-12 5 0 0 26 7161 hsa_M00386 Cul4-DDB1-CSA complex 0.999999999994625 -5.3752713152685e-12 5 0 0 26 7161 M00044 Tyrosine degradation, tyrosine => homogentisate 0.999999999994625 -5.3752713152685e-12 5 0 0 26 7161 M00405 THC complex 0.999999999994625 -5.3752713152685e-12 5 0 0 26 7161 M00037 Melatonin biosynthesis, tryptophan => serotonin => melatonin 0.999999999994625 -5.3752713152685e-12 5 0 0 26 7161 M00386 Cul4-DDB1-CSA complex 0.999999999994625 -5.3752713152685e-12 5 0 0 26 7161 M00307 Pyruvate oxidation, pyruvate => acetyl-CoA 0.999999999994625 -5.3752713152685e-12 5 0 0 26 7161 hsa_M00057 Glycosaminoglycan biosynthesis, linkage tetrasaccharide 0.999999999994625 -5.3752713152685e-12 5 0 0 26 7161 hsa00400 Phenylalanine, tyrosine and tryptophan biosynthesis 0.999999999994625 -5.3752713152685e-12 5 0 0 26 7161 hsa_M00307 Pyruvate oxidation, pyruvate => acetyl-CoA 0.999999999994625 -5.3752713152685e-12 5 0 0 26 7161 M00289 RF-C complex 0.999999999994625 -5.3752713152685e-12 5 0 0 26 7161 ko00524 Neomycin, kanamycin and gentamicin biosynthesis 0.999999999994625 -5.3752713152685e-12 5 0 0 26 7161 M00380 SCF-BTRC complex 0.999999999994625 -5.3752713152685e-12 5 0 0 26 7161 M00385 Cul4-DDB1-DDB2 complex 0.999999999994625 -5.3752713152685e-12 5 0 0 26 7161 ko00310 Lysine degradation 0.999999999995021 -4.97930150510474e-12 59 0 0 26 7161 ko04370 VEGF signaling pathway 0.999999999995021 -4.97930150510474e-12 59 0 0 26 7161 ko00561 Glycerolipid metabolism 0.999999999995021 -4.97930150510474e-12 59 0 0 26 7161 hsa00561 Glycerolipid metabolism 0.999999999995021 -4.97930150510474e-12 59 0 0 26 7161 hsa04370 VEGF signaling pathway 0.999999999995021 -4.97930150510474e-12 59 0 0 26 7161 hsa00310 Lysine degradation 0.999999999995021 -4.97930150510474e-12 59 0 0 26 7161 ko05310 Asthma 0.999999999995688 -4.3115168869485e-12 30 0 0 26 7161 ko00030 Pentose phosphate pathway 0.999999999995688 -4.3115168869485e-12 30 0 0 26 7161 ko00020 Citrate cycle (TCA cycle) 0.999999999995688 -4.3115168869485e-12 30 0 0 26 7161 hsa05310 Asthma 0.999999999995688 -4.3115168869485e-12 30 0 0 26 7161 hsa_M00354 Spliceosome, U4/U6.U5 tri-snRNP 0.999999999995688 -4.3115168869485e-12 30 0 0 26 7161 hsa00030 Pentose phosphate pathway 0.999999999995688 -4.3115168869485e-12 30 0 0 26 7161 hsa00020 Citrate cycle (TCA cycle) 0.999999999995688 -4.3115168869485e-12 30 0 0 26 7161 M00354 Spliceosome, U4/U6.U5 tri-snRNP 0.999999999995688 -4.3115168869485e-12 30 0 0 26 7161 ko04666 Fc gamma R-mediated phagocytosis 0.999999999996054 -3.94611706391939e-12 90 0 0 26 7161 hsa04666 Fc gamma R-mediated phagocytosis 0.999999999996054 -3.94611706391939e-12 90 0 0 26 7161 hsa_M00353 Spliceosome, Prp19/CDC5L complex 0.999999999996213 -3.78676903928923e-12 14 0 0 26 7161 M00147 NADH dehydrogenase (ubiquinone) 1 beta subcomplex 0.999999999996213 -3.78676903928923e-12 14 0 0 26 7161 M00353 Spliceosome, Prp19/CDC5L complex 0.999999999996213 -3.78676903928923e-12 14 0 0 26 7161 hsa_M00389 APC/C complex 0.999999999996213 -3.78676903928923e-12 14 0 0 26 7161 hsa_M00147 NADH dehydrogenase (ubiquinone) 1 beta subcomplex 0.999999999996213 -3.78676903928923e-12 14 0 0 26 7161 hsa_M00055 N-glycan precursor biosynthesis 0.999999999996213 -3.78676903928923e-12 14 0 0 26 7161 M00389 APC/C complex 0.999999999996213 -3.78676903928923e-12 14 0 0 26 7161 hsa_M00180 RNA polymerase II, eukaryotes 0.999999999996213 -3.78676903928923e-12 14 0 0 26 7161 M00011 Citrate cycle, second carbon oxidation, 2-oxoglutarate => oxaloacetate 0.999999999996213 -3.78676903928923e-12 14 0 0 26 7161 hsa_M00011 Citrate cycle, second carbon oxidation, 2-oxoglutarate => oxaloacetate 0.999999999996213 -3.78676903928923e-12 14 0 0 26 7161 M00180 RNA polymerase II, eukaryotes 0.999999999996213 -3.78676903928923e-12 14 0 0 26 7161 ko00533 Glycosaminoglycan biosynthesis - keratan sulfate 0.999999999996213 -3.78676903928923e-12 14 0 0 26 7161 M00055 N-glycan precursor biosynthesis 0.999999999996213 -3.78676903928923e-12 14 0 0 26 7161 hsa00533 Glycosaminoglycan biosynthesis - keratan sulfate 0.999999999996213 -3.78676903928923e-12 14 0 0 26 7161 hsa04721 Synaptic vesicle cycle 0.999999999996371 -3.62853565472907e-12 63 0 0 26 7161 hsa04623 Cytosolic DNA-sensing pathway 0.999999999996371 -3.62853565472907e-12 63 0 0 26 7161 ko04623 Cytosolic DNA-sensing pathway 0.999999999996371 -3.62853565472907e-12 63 0 0 26 7161 ko04721 Synaptic vesicle cycle 0.999999999996371 -3.62853565472907e-12 63 0 0 26 7161 hsa05219 Bladder cancer 0.999999999996381 -3.6186866168636e-12 41 0 0 26 7161 ko04975 Fat digestion and absorption 0.999999999996381 -3.6186866168636e-12 41 0 0 26 7161 ko03440 Homologous recombination 0.999999999996381 -3.6186866168636e-12 41 0 0 26 7161 ko05332 Graft-versus-host disease 0.999999999996381 -3.6186866168636e-12 41 0 0 26 7161 ko05219 Bladder cancer 0.999999999996381 -3.6186866168636e-12 41 0 0 26 7161 hsa04975 Fat digestion and absorption 0.999999999996381 -3.6186866168636e-12 41 0 0 26 7161 hsa05332 Graft-versus-host disease 0.999999999996381 -3.6186866168636e-12 41 0 0 26 7161 hsa03440 Homologous recombination 0.999999999996381 -3.6186866168636e-12 41 0 0 26 7161 ko05033 Nicotine addiction 0.999999999996717 -3.28294479186876e-12 40 0 0 26 7161 hsa04216 Ferroptosis 0.999999999996717 -3.28294479186876e-12 40 0 0 26 7161 hsa05033 Nicotine addiction 0.999999999996717 -3.28294479186876e-12 40 0 0 26 7161 hsa00380 Tryptophan metabolism 0.999999999996717 -3.28294479186876e-12 40 0 0 26 7161 ko00380 Tryptophan metabolism 0.999999999996717 -3.28294479186876e-12 40 0 0 26 7161 ko04216 Ferroptosis 0.999999999996717 -3.28294479186876e-12 40 0 0 26 7161 ko05203 Viral carcinogenesis 0.999999999996858 -3.14205903654865e-12 201 0 0 26 7161 hsa05203 Viral carcinogenesis 0.999999999996858 -3.14205903654865e-12 201 0 0 26 7161 ko04512 ECM-receptor interaction 0.999999999996961 -3.03891085541605e-12 82 0 0 26 7161 ko05204 Chemical carcinogenesis 0.999999999996961 -3.03891085541605e-12 82 0 0 26 7161 hsa05204 Chemical carcinogenesis 0.999999999996961 -3.03891085541605e-12 82 0 0 26 7161 ko04742 Taste transduction 0.999999999996961 -3.03891085541605e-12 82 0 0 26 7161 hsa04512 ECM-receptor interaction 0.999999999996961 -3.03891085541605e-12 82 0 0 26 7161 hsa04742 Taste transduction 0.999999999996961 -3.03891085541605e-12 82 0 0 26 7161 ko00563 Glycosylphosphatidylinositol (GPI)-anchor biosynthesis 0.999999999996971 -3.02935385511073e-12 25 0 0 26 7161 ko00592 alpha-Linolenic acid metabolism 0.999999999996971 -3.02935385511073e-12 25 0 0 26 7161 hsa00062 Fatty acid elongation 0.999999999996971 -3.02935385511073e-12 25 0 0 26 7161 hsa00563 Glycosylphosphatidylinositol (GPI)-anchor biosynthesis 0.999999999996971 -3.02935385511073e-12 25 0 0 26 7161 ko00062 Fatty acid elongation 0.999999999996971 -3.02935385511073e-12 25 0 0 26 7161 hsa00592 alpha-Linolenic acid metabolism 0.999999999996971 -3.02935385511073e-12 25 0 0 26 7161 M00001 Glycolysis (Embden-Meyerhof pathway), glucose => pyruvate 0.999999999996971 -3.02935385511073e-12 25 0 0 26 7161 hsa_M00001 Glycolysis (Embden-Meyerhof pathway), glucose => pyruvate 0.999999999996971 -3.02935385511073e-12 25 0 0 26 7161 ko04120 Ubiquitin mediated proteolysis 0.999999999997041 -2.95867175690671e-12 137 0 0 26 7161 hsa04120 Ubiquitin mediated proteolysis 0.999999999997041 -2.95867175690671e-12 137 0 0 26 7161 hsa04550 Signaling pathways regulating pluripotency of stem cells 0.999999999997337 -2.66290221565061e-12 139 0 0 26 7161 ko04550 Signaling pathways regulating pluripotency of stem cells 0.999999999997337 -2.66290221565061e-12 139 0 0 26 7161 ko04810 Regulation of actin cytoskeleton 0.999999999997384 -2.61555391563714e-12 211 0 0 26 7161 hsa04810 Regulation of actin cytoskeleton 0.999999999997384 -2.61555391563714e-12 211 0 0 26 7161 hsa04650 Natural killer cell mediated cytotoxicity 0.999999999997651 -2.34869196852059e-12 132 0 0 26 7161 ko05322 Systemic lupus erythematosus 0.999999999997651 -2.34869196852059e-12 132 0 0 26 7161 ko04650 Natural killer cell mediated cytotoxicity 0.999999999997651 -2.34869196852059e-12 132 0 0 26 7161 hsa05322 Systemic lupus erythematosus 0.999999999997651 -2.34869196852059e-12 132 0 0 26 7161 ko03040 Spliceosome 0.999999999997651 -2.34869196852059e-12 132 0 0 26 7161 hsa03040 Spliceosome 0.999999999997651 -2.34869196852059e-12 132 0 0 26 7161 ko04064 NF-kappa B signaling pathway 0.99999999999779 -2.21014459951804e-12 94 0 0 26 7161 hsa04064 NF-kappa B signaling pathway 0.99999999999779 -2.21014459951804e-12 94 0 0 26 7161 hsa04744 Phototransduction 0.999999999998162 -1.83837258730735e-12 28 0 0 26 7161 ko00630 Glyoxylate and dicarboxylate metabolism 0.999999999998162 -1.83837258730735e-12 28 0 0 26 7161 hsa00650 Butanoate metabolism 0.999999999998162 -1.83837258730735e-12 28 0 0 26 7161 hsa00630 Glyoxylate and dicarboxylate metabolism 0.999999999998162 -1.83837258730735e-12 28 0 0 26 7161 ko00650 Butanoate metabolism 0.999999999998162 -1.83837258730735e-12 28 0 0 26 7161 ko04744 Phototransduction 0.999999999998162 -1.83837258730735e-12 28 0 0 26 7161 hsa04950 Maturity onset diabetes of the young 0.999999999998401 -1.59946560724374e-12 26 0 0 26 7161 ko04950 Maturity onset diabetes of the young 0.999999999998401 -1.59946560724374e-12 26 0 0 26 7161 ko03013 RNA transport 0.999999999998514 -1.48562381187886e-12 166 0 0 26 7161 hsa03013 RNA transport 0.999999999998514 -1.48562381187886e-12 166 0 0 26 7161 ko00051 Fructose and mannose metabolism 0.99999999999882 -1.18012786650625e-12 33 0 0 26 7161 hsa03410 Base excision repair 0.99999999999882 -1.18012786650625e-12 33 0 0 26 7161 hsa00051 Fructose and mannose metabolism 0.99999999999882 -1.18012786650625e-12 33 0 0 26 7161 ko03410 Base excision repair 0.99999999999882 -1.18012786650625e-12 33 0 0 26 7161 hsa_M00296 BER complex 0.999999999999183 -8.17121003602109e-13 10 0 0 26 7161 ko00072 Synthesis and degradation of ketone bodies 0.999999999999183 -8.17121003602109e-13 10 0 0 26 7161 M00681 Activin signaling 0.999999999999183 -8.17121003602109e-13 10 0 0 26 7161 M00693 Cell cycle - G2/M transition 0.999999999999183 -8.17121003602109e-13 10 0 0 26 7161 hsa_M00152 Cytochrome bc1 complex 0.999999999999183 -8.17121003602109e-13 10 0 0 26 7161 M00391 Exosome, eukaryotes 0.999999999999183 -8.17121003602109e-13 10 0 0 26 7161 hsa_M00693 Cell cycle - G2/M transition 0.999999999999183 -8.17121003602109e-13 10 0 0 26 7161 M00413 FA core complex 0.999999999999183 -8.17121003602109e-13 10 0 0 26 7161 hsa_M00681 Activin signaling 0.999999999999183 -8.17121003602109e-13 10 0 0 26 7161 M00426 Survival motor neuron (SMN) complex 0.999999999999183 -8.17121003602109e-13 10 0 0 26 7161 M00351 Spliceosome, U1-snRNP 0.999999999999183 -8.17121003602109e-13 10 0 0 26 7161 M00152 Cytochrome bc1 complex 0.999999999999183 -8.17121003602109e-13 10 0 0 26 7161 ko00920 Sulfur metabolism 0.999999999999183 -8.17121003602109e-13 10 0 0 26 7161 hsa_M00095 C5 isoprenoid biosynthesis, mevalonate pathway 0.999999999999183 -8.17121003602109e-13 10 0 0 26 7161 hsa_M00059 Glycosaminoglycan biosynthesis, heparan sulfate backbone 0.999999999999183 -8.17121003602109e-13 10 0 0 26 7161 hsa_M00413 FA core complex 0.999999999999183 -8.17121003602109e-13 10 0 0 26 7161 hsa00920 Sulfur metabolism 0.999999999999183 -8.17121003602109e-13 10 0 0 26 7161 M00095 C5 isoprenoid biosynthesis, mevalonate pathway 0.999999999999183 -8.17121003602109e-13 10 0 0 26 7161 M00296 BER complex 0.999999999999183 -8.17121003602109e-13 10 0 0 26 7161 M00059 Glycosaminoglycan biosynthesis, heparan sulfate backbone 0.999999999999183 -8.17121003602109e-13 10 0 0 26 7161 hsa00072 Synthesis and degradation of ketone bodies 0.999999999999183 -8.17121003602109e-13 10 0 0 26 7161 hsa_M00351 Spliceosome, U1-snRNP 0.999999999999183 -8.17121003602109e-13 10 0 0 26 7161 hsa_M00426 Survival motor neuron (SMN) complex 0.999999999999183 -8.17121003602109e-13 10 0 0 26 7161 hsa_M00391 Exosome, eukaryotes 0.999999999999183 -8.17121003602109e-13 10 0 0 26 7161 ko01200 Carbon metabolism 0.999999999999232 -7.68289308968369e-13 114 0 0 26 7161 hsa01200 Carbon metabolism 0.999999999999232 -7.68289308968369e-13 114 0 0 26 7161 hsa_M00284 Origin recognition complex 0.99999999999931 -6.90346915446269e-13 6 0 0 26 7161 hsa_M00141 C1-unit interconversion, eukaryotes 0.99999999999931 -6.90346915446269e-13 6 0 0 26 7161 hsa00750 Vitamin B6 metabolism 0.99999999999931 -6.90346915446269e-13 6 0 0 26 7161 ko00440 Phosphonate and phosphinate metabolism 0.99999999999931 -6.90346915446269e-13 6 0 0 26 7161 hsa_M00085 Fatty acid biosynthesis, elongation, mitochondria 0.99999999999931 -6.90346915446269e-13 6 0 0 26 7161 hsa_M00013 Malonate semialdehyde pathway, propanoyl-CoA => acetyl-CoA 0.99999999999931 -6.90346915446269e-13 6 0 0 26 7161 hsa_M00109 C21-Steroid hormone biosynthesis, progesterone => cortisol/cortisone 0.99999999999931 -6.90346915446269e-13 6 0 0 26 7161 ko00750 Vitamin B6 metabolism 0.99999999999931 -6.90346915446269e-13 6 0 0 26 7161 M00141 C1-unit interconversion, eukaryotes 0.99999999999931 -6.90346915446269e-13 6 0 0 26 7161 hsa_M00285 MCM complex 0.99999999999931 -6.90346915446269e-13 6 0 0 26 7161 hsa_M00424 Shelterin complex 0.99999999999931 -6.90346915446269e-13 6 0 0 26 7161 M00073 N-glycan precursor trimming 0.99999999999931 -6.90346915446269e-13 6 0 0 26 7161 M00109 C21-Steroid hormone biosynthesis, progesterone => cortisol/cortisone 0.99999999999931 -6.90346915446269e-13 6 0 0 26 7161 M00424 Shelterin complex 0.99999999999931 -6.90346915446269e-13 6 0 0 26 7161 M00013 Malonate semialdehyde pathway, propanoyl-CoA => acetyl-CoA 0.99999999999931 -6.90346915446269e-13 6 0 0 26 7161 hsa_M00073 N-glycan precursor trimming 0.99999999999931 -6.90346915446269e-13 6 0 0 26 7161 hsa_M00090 Phosphatidylcholine (PC) biosynthesis, choline => PC 0.99999999999931 -6.90346915446269e-13 6 0 0 26 7161 M00395 Decapping complex 0.99999999999931 -6.90346915446269e-13 6 0 0 26 7161 hsa_M00029 Urea cycle 0.99999999999931 -6.90346915446269e-13 6 0 0 26 7161 M00029 Urea cycle 0.99999999999931 -6.90346915446269e-13 6 0 0 26 7161 M00090 Phosphatidylcholine (PC) biosynthesis, choline => PC 0.99999999999931 -6.90346915446269e-13 6 0 0 26 7161 hsa_M00048 Inosine monophosphate biosynthesis, PRPP + glutamine => IMP 0.99999999999931 -6.90346915446269e-13 6 0 0 26 7161 M00048 Inosine monophosphate biosynthesis, PRPP + glutamine => IMP 0.99999999999931 -6.90346915446269e-13 6 0 0 26 7161 M00085 Fatty acid biosynthesis, elongation, mitochondria 0.99999999999931 -6.90346915446269e-13 6 0 0 26 7161 hsa_M00058 Glycosaminoglycan biosynthesis, chondroitin sulfate backbone 0.99999999999931 -6.90346915446269e-13 6 0 0 26 7161 M00285 MCM complex 0.99999999999931 -6.90346915446269e-13 6 0 0 26 7161 hsa_M00395 Decapping complex 0.99999999999931 -6.90346915446269e-13 6 0 0 26 7161 M00058 Glycosaminoglycan biosynthesis, chondroitin sulfate backbone 0.99999999999931 -6.90346915446269e-13 6 0 0 26 7161 M00284 Origin recognition complex 0.99999999999931 -6.90346915446269e-13 6 0 0 26 7161 hsa00440 Phosphonate and phosphinate metabolism 0.99999999999931 -6.90346915446269e-13 6 0 0 26 7161 ko00590 Arachidonic acid metabolism 0.999999999999439 -5.61352043735373e-13 62 0 0 26 7161 hsa00590 Arachidonic acid metabolism 0.999999999999439 -5.61352043735373e-13 62 0 0 26 7161 M00135 GABA biosynthesis, eukaryotes, putrescine => GABA 1.00000000000005 4.91548617360632e-14 9 0 0 26 7161 M00076 Dermatan sulfate degradation 1.00000000000005 4.91548617360632e-14 9 0 0 26 7161 hsa_M00135 GABA biosynthesis, eukaryotes, putrescine => GABA 1.00000000000005 4.91548617360632e-14 9 0 0 26 7161 hsa_M00076 Dermatan sulfate degradation 1.00000000000005 4.91548617360632e-14 9 0 0 26 7161 hsa_M00131 Inositol phosphate metabolism, Ins(1,3,4,5)P4 => Ins(1,3,4)P3 => myo-inositol 1.00000000000005 4.91548617360632e-14 9 0 0 26 7161 hsa_M00361 Nucleotide sugar biosynthesis, eukaryotes 1.00000000000005 4.91548617360632e-14 9 0 0 26 7161 M00361 Nucleotide sugar biosynthesis, eukaryotes 1.00000000000005 4.91548617360632e-14 9 0 0 26 7161 M00131 Inositol phosphate metabolism, Ins(1,3,4,5)P4 => Ins(1,3,4)P3 => myo-inositol 1.00000000000005 4.91548617360632e-14 9 0 0 26 7161 hsa05220 Chronic myeloid leukemia 1.00000000000014 1.37555108180926e-13 71 0 0 26 7161 ko05220 Chronic myeloid leukemia 1.00000000000014 1.37555108180926e-13 71 0 0 26 7161 ko03450 Non-homologous end-joining 1.00000000000017 1.73722300511147e-13 13 0 0 26 7161 ko00061 Fatty acid biosynthesis 1.00000000000017 1.73722300511147e-13 13 0 0 26 7161 M00692 Cell cycle - G1/S transition 1.00000000000017 1.73722300511147e-13 13 0 0 26 7161 M00036 Leucine degradation, leucine => acetoacetate + acetyl-CoA 1.00000000000017 1.73722300511147e-13 13 0 0 26 7161 hsa_M00415 Fatty acid biosynthesis, elongation, endoplasmic reticulum 1.00000000000017 1.73722300511147e-13 13 0 0 26 7161 M00403 HRD1/SEL1 ERAD complex 1.00000000000017 1.73722300511147e-13 13 0 0 26 7161 hsa03450 Non-homologous end-joining 1.00000000000017 1.73722300511147e-13 13 0 0 26 7161 M00415 Fatty acid biosynthesis, elongation, endoplasmic reticulum 1.00000000000017 1.73722300511147e-13 13 0 0 26 7161 hsa_M00036 Leucine degradation, leucine => acetoacetate + acetyl-CoA 1.00000000000017 1.73722300511147e-13 13 0 0 26 7161 hsa_M00403 HRD1/SEL1 ERAD complex 1.00000000000017 1.73722300511147e-13 13 0 0 26 7161 hsa_M00692 Cell cycle - G1/S transition 1.00000000000017 1.73722300511147e-13 13 0 0 26 7161 hsa00061 Fatty acid biosynthesis 1.00000000000017 1.73722300511147e-13 13 0 0 26 7161 hsa_M00050 Guanine ribonucleotide biosynthesis IMP => GDP,GTP 1.00000000000017 1.73722300511147e-13 13 0 0 26 7161 hsa_M00676 PI3K-Akt signaling 1.00000000000017 1.73722300511147e-13 13 0 0 26 7161 M00676 PI3K-Akt signaling 1.00000000000017 1.73722300511147e-13 13 0 0 26 7161 M00050 Guanine ribonucleotide biosynthesis IMP => GDP,GTP 1.00000000000017 1.73722300511147e-13 13 0 0 26 7161 ko03022 Basal transcription factors 1.00000000000019 1.92478697826484e-13 45 0 0 26 7161 ko00565 Ether lipid metabolism 1.00000000000019 1.92478697826484e-13 45 0 0 26 7161 hsa_M00427 Nuclear pore complex 1.00000000000019 1.92478697826484e-13 45 0 0 26 7161 hsa03050 Proteasome 1.00000000000019 1.92478697826484e-13 45 0 0 26 7161 hsa00565 Ether lipid metabolism 1.00000000000019 1.92478697826484e-13 45 0 0 26 7161 hsa03022 Basal transcription factors 1.00000000000019 1.92478697826484e-13 45 0 0 26 7161 ko03050 Proteasome 1.00000000000019 1.92478697826484e-13 45 0 0 26 7161 M00427 Nuclear pore complex 1.00000000000019 1.92478697826484e-13 45 0 0 26 7161 hsa04151 PI3K-Akt signaling pathway 1.00000000000038 3.80204834514903e-13 341 0 0 26 7161 ko04151 PI3K-Akt signaling pathway 1.00000000000038 3.80204834514903e-13 341 0 0 26 7161 hsa01230 Biosynthesis of amino acids 1.00000000000052 5.22146810355818e-13 74 0 0 26 7161 ko01230 Biosynthesis of amino acids 1.00000000000052 5.22146810355818e-13 74 0 0 26 7161 M00687 MAPK (ERK1/2) signaling 1.00000000000082 8.24609492272732e-13 8 0 0 26 7161 M00077 Chondroitin sulfate degradation 1.00000000000082 8.24609492272732e-13 8 0 0 26 7161 ko00740 Riboflavin metabolism 1.00000000000082 8.24609492272732e-13 8 0 0 26 7161 M00065 GPI-anchor biosynthesis, core oligosaccharide 1.00000000000082 8.24609492272732e-13 8 0 0 26 7161 hsa_M00687 MAPK (ERK1/2) signaling 1.00000000000082 8.24609492272732e-13 8 0 0 26 7161 hsa_M00077 Chondroitin sulfate degradation 1.00000000000082 8.24609492272732e-13 8 0 0 26 7161 hsa_M00428 eIF4F complex 1.00000000000082 8.24609492272732e-13 8 0 0 26 7161 M00010 Citrate cycle, first carbon oxidation, oxaloacetate => 2-oxoglutarate 1.00000000000082 8.24609492272732e-13 8 0 0 26 7161 hsa_M00680 TGF-beta signaling 1.00000000000082 8.24609492272732e-13 8 0 0 26 7161 hsa00740 Riboflavin metabolism 1.00000000000082 8.24609492272732e-13 8 0 0 26 7161 hsa_M00409 ESCRT-I complex 1.00000000000082 8.24609492272732e-13 8 0 0 26 7161 M00428 eIF4F complex 1.00000000000082 8.24609492272732e-13 8 0 0 26 7161 hsa04122 Sulfur relay system 1.00000000000082 8.24609492272732e-13 8 0 0 26 7161 M00409 ESCRT-I complex 1.00000000000082 8.24609492272732e-13 8 0 0 26 7161 M00406 TREX complex 1.00000000000082 8.24609492272732e-13 8 0 0 26 7161 M00680 TGF-beta signaling 1.00000000000082 8.24609492272732e-13 8 0 0 26 7161 hsa_M00406 TREX complex 1.00000000000082 8.24609492272732e-13 8 0 0 26 7161 hsa_M00065 GPI-anchor biosynthesis, core oligosaccharide 1.00000000000082 8.24609492272732e-13 8 0 0 26 7161 hsa_M00010 Citrate cycle, first carbon oxidation, oxaloacetate => 2-oxoglutarate 1.00000000000082 8.24609492272732e-13 8 0 0 26 7161 ko04122 Sulfur relay system 1.00000000000082 8.24609492272732e-13 8 0 0 26 7161 hsa04612 Antigen processing and presentation 1.00000000000112 1.12052916722029e-12 77 0 0 26 7161 ko04612 Antigen processing and presentation 1.00000000000112 1.12052916722029e-12 77 0 0 26 7161 ko03018 RNA degradation 1.00000000000112 1.12052916722029e-12 77 0 0 26 7161 hsa03018 RNA degradation 1.00000000000112 1.12052916722029e-12 77 0 0 26 7161 ko05323 Rheumatoid arthritis 1.00000000000124 1.23755343685123e-12 89 0 0 26 7161 hsa05323 Rheumatoid arthritis 1.00000000000124 1.23755343685123e-12 89 0 0 26 7161 ko00860 Porphyrin and chlorophyll metabolism 1.00000000000134 1.34432563628766e-12 42 0 0 26 7161 hsa00860 Porphyrin and chlorophyll metabolism 1.00000000000134 1.34432563628766e-12 42 0 0 26 7161 hsa05410 Hypertrophic cardiomyopathy (HCM) 1.00000000000138 1.38161237458631e-12 83 0 0 26 7161 ko04146 Peroxisome 1.00000000000138 1.38161237458631e-12 83 0 0 26 7161 hsa04146 Peroxisome 1.00000000000138 1.38161237458631e-12 83 0 0 26 7161 ko05410 Hypertrophic cardiomyopathy (HCM) 1.00000000000138 1.38161237458631e-12 83 0 0 26 7161 hsa00071 Fatty acid degradation 1.00000000000147 1.46807831461517e-12 44 0 0 26 7161 ko02010 ABC transporters 1.00000000000147 1.46807831461517e-12 44 0 0 26 7161 hsa00970 Aminoacyl-tRNA biosynthesis 1.00000000000147 1.46807831461517e-12 44 0 0 26 7161 ko00970 Aminoacyl-tRNA biosynthesis 1.00000000000147 1.46807831461517e-12 44 0 0 26 7161 ko00071 Fatty acid degradation 1.00000000000147 1.46807831461517e-12 44 0 0 26 7161 hsa02010 ABC transporters 1.00000000000147 1.46807831461517e-12 44 0 0 26 7161 hsa05030 Cocaine addiction 1.00000000000161 1.61003873088439e-12 49 0 0 26 7161 ko00330 Arginine and proline metabolism 1.00000000000161 1.61003873088439e-12 49 0 0 26 7161 hsa00330 Arginine and proline metabolism 1.00000000000161 1.61003873088439e-12 49 0 0 26 7161 ko05030 Cocaine addiction 1.00000000000161 1.61003873088439e-12 49 0 0 26 7161 hsa05144 Malaria 1.00000000000161 1.61003873088439e-12 49 0 0 26 7161 ko05144 Malaria 1.00000000000161 1.61003873088439e-12 49 0 0 26 7161 ko00900 Terpenoid backbone biosynthesis 1.00000000000166 1.65892697976172e-12 22 0 0 26 7161 M00009 Citrate cycle (TCA cycle, Krebs cycle) 1.00000000000166 1.65892697976172e-12 22 0 0 26 7161 hsa_M00689 MAPK (p38) signaling 1.00000000000166 1.65892697976172e-12 22 0 0 26 7161 hsa00514 Other types of O-glycan biosynthesis 1.00000000000166 1.65892697976172e-12 22 0 0 26 7161 M00689 MAPK (p38) signaling 1.00000000000166 1.65892697976172e-12 22 0 0 26 7161 hsa_M00009 Citrate cycle (TCA cycle, Krebs cycle) 1.00000000000166 1.65892697976172e-12 22 0 0 26 7161 ko00514 Other types of O-glycan biosynthesis 1.00000000000166 1.65892697976172e-12 22 0 0 26 7161 hsa00900 Terpenoid backbone biosynthesis 1.00000000000166 1.65892697976172e-12 22 0 0 26 7161 M00177 Ribosome, eukaryotes 1.00000000000243 2.43162560401067e-12 91 0 0 26 7161 hsa_M00177 Ribosome, eukaryotes 1.00000000000243 2.43162560401067e-12 91 0 0 26 7161 hsa00983 Drug metabolism - other enzymes 1.00000000000253 2.52846250405887e-12 46 0 0 26 7161 ko00983 Drug metabolism - other enzymes 1.00000000000253 2.52846250405887e-12 46 0 0 26 7161 ko05211 Renal cell carcinoma 1.00000000000272 2.71996180046863e-12 64 0 0 26 7161 hsa05214 Glioma 1.00000000000272 2.71996180046863e-12 64 0 0 26 7161 ko05214 Glioma 1.00000000000272 2.71996180046863e-12 64 0 0 26 7161 hsa05211 Renal cell carcinoma 1.00000000000272 2.71996180046863e-12 64 0 0 26 7161 hsa_M00101 Cholesterol biosynthesis, squalene 2,3-epoxide => cholesterol 1.0000000000031 3.09847450065688e-12 11 0 0 26 7161 ko00130 Ubiquinone and other terpenoid-quinone biosynthesis 1.0000000000031 3.09847450065688e-12 11 0 0 26 7161 hsa_M00404 COPII complex 1.0000000000031 3.09847450065688e-12 11 0 0 26 7161 hsa00130 Ubiquinone and other terpenoid-quinone biosynthesis 1.0000000000031 3.09847450065688e-12 11 0 0 26 7161 hsa_M00032 Lysine degradation, lysine => saccharopine => acetoacetyl-CoA 1.0000000000031 3.09847450065688e-12 11 0 0 26 7161 hsa_M00034 Methionine salvage pathway 1.0000000000031 3.09847450065688e-12 11 0 0 26 7161 M00034 Methionine salvage pathway 1.0000000000031 3.09847450065688e-12 11 0 0 26 7161 M00143 NADH dehydrogenase (ubiquinone) Fe-S protein/flavoprotein complex, mitochondria 1.0000000000031 3.09847450065688e-12 11 0 0 26 7161 hsa_M00678 Hedgehog signaling 1.0000000000031 3.09847450065688e-12 11 0 0 26 7161 hsa00430 Taurine and hypotaurine metabolism 1.0000000000031 3.09847450065688e-12 11 0 0 26 7161 M00098 Acylglycerol degradation 1.0000000000031 3.09847450065688e-12 11 0 0 26 7161 M00404 COPII complex 1.0000000000031 3.09847450065688e-12 11 0 0 26 7161 hsa_M00143 NADH dehydrogenase (ubiquinone) Fe-S protein/flavoprotein complex, mitochondria 1.0000000000031 3.09847450065688e-12 11 0 0 26 7161 ko00430 Taurine and hypotaurine metabolism 1.0000000000031 3.09847450065688e-12 11 0 0 26 7161 M00101 Cholesterol biosynthesis, squalene 2,3-epoxide => cholesterol 1.0000000000031 3.09847450065688e-12 11 0 0 26 7161 M00032 Lysine degradation, lysine => saccharopine => acetoacetyl-CoA 1.0000000000031 3.09847450065688e-12 11 0 0 26 7161 hsa_M00098 Acylglycerol degradation 1.0000000000031 3.09847450065688e-12 11 0 0 26 7161 M00678 Hedgehog signaling 1.0000000000031 3.09847450065688e-12 11 0 0 26 7161 hsa03010 Ribosome 1.00000000000372 3.71995612028818e-12 134 0 0 26 7161 ko03010 Ribosome 1.00000000000372 3.71995612028818e-12 134 0 0 26 7161 hsa_M00154 Cytochrome c oxidase 1.00000000000448 4.47738885266936e-12 21 0 0 26 7161 hsa00220 Arginine biosynthesis 1.00000000000448 4.47738885266936e-12 21 0 0 26 7161 M00049 Adenine ribonucleotide biosynthesis, IMP => ADP,ATP 1.00000000000448 4.47738885266936e-12 21 0 0 26 7161 ko00220 Arginine biosynthesis 1.00000000000448 4.47738885266936e-12 21 0 0 26 7161 M00154 Cytochrome c oxidase 1.00000000000448 4.47738885266936e-12 21 0 0 26 7161 hsa_M00049 Adenine ribonucleotide biosynthesis, IMP => ADP,ATP 1.00000000000448 4.47738885266936e-12 21 0 0 26 7161 ko05218 Melanoma 1.00000000000468 4.6839860594165e-12 69 0 0 26 7161 hsa00982 Drug metabolism - cytochrome P450 1.00000000000468 4.6839860594165e-12 69 0 0 26 7161 ko00982 Drug metabolism - cytochrome P450 1.00000000000468 4.6839860594165e-12 69 0 0 26 7161 hsa05218 Melanoma 1.00000000000468 4.6839860594165e-12 69 0 0 26 7161 hsa04115 p53 signaling pathway 1.00000000000468 4.6839860594165e-12 69 0 0 26 7161 ko04115 p53 signaling pathway 1.00000000000468 4.6839860594165e-12 69 0 0 26 7161 hsa00601 Glycosphingolipid biosynthesis - lacto and neolacto series 1.00000000000482 4.81754858366208e-12 27 0 0 26 7161 hsa_M00056 O-glycan biosynthesis, mucin type core 1.00000000000482 4.81754858366208e-12 27 0 0 26 7161 M00014 Glucuronate pathway (uronate pathway) 1.00000000000482 4.81754858366208e-12 27 0 0 26 7161 ko04966 Collecting duct acid secretion 1.00000000000482 4.81754858366208e-12 27 0 0 26 7161 ko00601 Glycosphingolipid biosynthesis - lacto and neolacto series 1.00000000000482 4.81754858366208e-12 27 0 0 26 7161 ko00053 Ascorbate and aldarate metabolism 1.00000000000482 4.81754858366208e-12 27 0 0 26 7161 hsa_M00014 Glucuronate pathway (uronate pathway) 1.00000000000482 4.81754858366208e-12 27 0 0 26 7161 M00056 O-glycan biosynthesis, mucin type core 1.00000000000482 4.81754858366208e-12 27 0 0 26 7161 hsa00053 Ascorbate and aldarate metabolism 1.00000000000482 4.81754858366208e-12 27 0 0 26 7161 hsa04966 Collecting duct acid secretion 1.00000000000482 4.81754858366208e-12 27 0 0 26 7161 hsa00190 Oxidative phosphorylation 1.00000000000512 5.12105516944718e-12 120 0 0 26 7161 ko04152 AMPK signaling pathway 1.00000000000512 5.12105516944718e-12 120 0 0 26 7161 hsa04152 AMPK signaling pathway 1.00000000000512 5.12105516944718e-12 120 0 0 26 7161 ko00190 Oxidative phosphorylation 1.00000000000512 5.12105516944718e-12 120 0 0 26 7161 ko03008 Ribosome biogenesis in eukaryotes 1.00000000000585 5.84646236257509e-12 79 0 0 26 7161 ko01521 EGFR tyrosine kinase inhibitor resistance 1.00000000000585 5.84646236257509e-12 79 0 0 26 7161 hsa03008 Ribosome biogenesis in eukaryotes 1.00000000000585 5.84646236257509e-12 79 0 0 26 7161 hsa01521 EGFR tyrosine kinase inhibitor resistance 1.00000000000585 5.84646236257509e-12 79 0 0 26 7161 hsa05206 MicroRNAs in cancer 1.00000000000592 5.91558712306212e-12 299 0 0 26 7161 ko05206 MicroRNAs in cancer 1.00000000000592 5.91558712306212e-12 299 0 0 26 7161 ko04060 Cytokine-cytokine receptor interaction 1.00000000000649 6.48709198468024e-12 270 0 0 26 7161 hsa04060 Cytokine-cytokine receptor interaction 1.00000000000649 6.48709198468024e-12 270 0 0 26 7161 ko05215 Prostate cancer 1.00000000000664 6.63827169804389e-12 87 0 0 26 7161 hsa05215 Prostate cancer 1.00000000000664 6.63827169804389e-12 87 0 0 26 7161 hsa05162 Measles 1.00000000000697 6.97318479670112e-12 133 0 0 26 7161 ko05162 Measles 1.00000000000697 6.97318479670112e-12 133 0 0 26 7161 hsa04630 Jak-STAT signaling pathway 1.00000000000809 8.09344688859536e-12 156 0 0 26 7161 ko04630 Jak-STAT signaling pathway 1.00000000000809 8.09344688859536e-12 156 0 0 26 7161 ko00760 Nicotinate and nicotinamide metabolism 1.0000000000087 8.69766803847355e-12 29 0 0 26 7161 hsa05216 Thyroid cancer 1.0000000000087 8.69766803847355e-12 29 0 0 26 7161 ko05216 Thyroid cancer 1.0000000000087 8.69766803847355e-12 29 0 0 26 7161 ko04392 Hippo signaling pathway -multiple species 1.0000000000087 8.69766803847355e-12 29 0 0 26 7161 hsa00591 Linoleic acid metabolism 1.0000000000087 8.69766803847355e-12 29 0 0 26 7161 ko00591 Linoleic acid metabolism 1.0000000000087 8.69766803847355e-12 29 0 0 26 7161 hsa04392 Hippo signaling pathway -multiple species 1.0000000000087 8.69766803847355e-12 29 0 0 26 7161 hsa00760 Nicotinate and nicotinamide metabolism 1.0000000000087 8.69766803847355e-12 29 0 0 26 7161 hsa_M00388 ECS complex 1.00000000000909 9.09308657821449e-12 12 0 0 26 7161 hsa_M00412 ESCRT-III complex 1.00000000000909 9.09308657821449e-12 12 0 0 26 7161 M00412 ESCRT-III complex 1.00000000000909 9.09308657821449e-12 12 0 0 26 7161 M00087 beta-Oxidation 1.00000000000909 9.09308657821449e-12 12 0 0 26 7161 M00052 Pyrimidine ribonucleotide biosynthesis, UMP => UDP/UTP,CDP/CTP 1.00000000000909 9.09308657821449e-12 12 0 0 26 7161 M00182 RNA polymerase I, eukaryotes 1.00000000000909 9.09308657821449e-12 12 0 0 26 7161 M00104 Bile acid biosynthesis, cholesterol => cholate/chenodeoxycholate 1.00000000000909 9.09308657821449e-12 12 0 0 26 7161 hsa_M00087 beta-Oxidation 1.00000000000909 9.09308657821449e-12 12 0 0 26 7161 hsa_M00104 Bile acid biosynthesis, cholesterol => cholate/chenodeoxycholate 1.00000000000909 9.09308657821449e-12 12 0 0 26 7161 M00004 Pentose phosphate pathway (Pentose phosphate cycle) 1.00000000000909 9.09308657821449e-12 12 0 0 26 7161 hsa_M00004 Pentose phosphate pathway (Pentose phosphate cycle) 1.00000000000909 9.09308657821449e-12 12 0 0 26 7161 hsa_M00002 Glycolysis, core module involving three-carbon compounds 1.00000000000909 9.09308657821449e-12 12 0 0 26 7161 M00290 Holo-TFIIH complex 1.00000000000909 9.09308657821449e-12 12 0 0 26 7161 M00094 Ceramide biosynthesis 1.00000000000909 9.09308657821449e-12 12 0 0 26 7161 hsa_M00182 RNA polymerase I, eukaryotes 1.00000000000909 9.09308657821449e-12 12 0 0 26 7161 M00002 Glycolysis, core module involving three-carbon compounds 1.00000000000909 9.09308657821449e-12 12 0 0 26 7161 hsa_M00094 Ceramide biosynthesis 1.00000000000909 9.09308657821449e-12 12 0 0 26 7161 hsa_M00052 Pyrimidine ribonucleotide biosynthesis, UMP => UDP/UTP,CDP/CTP 1.00000000000909 9.09308657821449e-12 12 0 0 26 7161 hsa_M00290 Holo-TFIIH complex 1.00000000000909 9.09308657821449e-12 12 0 0 26 7161 M00388 ECS complex 1.00000000000909 9.09308657821449e-12 12 0 0 26 7161 ko00980 Metabolism of xenobiotics by cytochrome P450 1.00000000000967 9.66903995980546e-12 73 0 0 26 7161 hsa01524 Platinum drug resistance 1.00000000000967 9.66903995980546e-12 73 0 0 26 7161 hsa00980 Metabolism of xenobiotics by cytochrome P450 1.00000000000967 9.66903995980546e-12 73 0 0 26 7161 ko01524 Platinum drug resistance 1.00000000000967 9.66903995980546e-12 73 0 0 26 7161 hsa04066 HIF-1 signaling pathway 1.00000000001294 1.29402804260448e-11 101 0 0 26 7161 hsa04145 Phagosome 1.00000000001407 1.4069290462914e-11 152 0 0 26 7161 ko04145 Phagosome 1.00000000001407 1.4069290462914e-11 152 0 0 26 7161 hsa00140 Steroid hormone biosynthesis 1.00000000001444 1.44381289658493e-11 58 0 0 26 7161 ko05223 Non-small cell lung cancer 1.00000000001444 1.44381289658493e-11 58 0 0 26 7161 hsa05223 Non-small cell lung cancer 1.00000000001444 1.44381289658493e-11 58 0 0 26 7161 ko00140 Steroid hormone biosynthesis 1.00000000001444 1.44381289658493e-11 58 0 0 26 7161 hsa05416 Viral myocarditis 1.00000000001444 1.44381289658493e-11 58 0 0 26 7161