P-value | ln(P) | Term | GO Tree | GO ID | # of Genes in Term | # of Target Genes in Term | # of Total Genes | # of Target Genes | Common Genes |
1.086e-11 | -25.25 | haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-Burkitt_lymphoma | COSMIC cancer mutations | haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-Burkitt_lymphoma | 2119 | 26 | 16828 | 49 |
BMPR1B,ITPR2,CSGALNACT1,LRIG1,LSAMP,SLC1A3,SASH1,PCDH9,NPAS3,SOX5,FBXL7,NHSL1,ADCY2,NRG3,RFX4,PPP2R2B,GPM6A,PRKG1,RYR3,ATP13A4,CTNND2,SLC1A2,GPC5,NKAIN3,MAML2,NTRK2 |
1.086e-11 | -25.25 | Burkitt_lymphoma | COSMIC cancer mutations | Burkitt_lymphoma | 2119 | 26 | 16828 | 49 |
LRIG1,CSGALNACT1,ITPR2,BMPR1B,SOX5,NPAS3,PCDH9,SASH1,SLC1A3,LSAMP,FBXL7,GPM6A,PPP2R2B,NRG3,RFX4,NHSL1,ADCY2,ATP13A4,RYR3,PRKG1,CTNND2,NKAIN3,GPC5,SLC1A2,NTRK2,MAML2 |
6.000e-10 | -21.23 | prostate-carcinoma | COSMIC cancer mutations | prostate-carcinoma | 9000 | 46 | 16828 | 49 |
MSI2,FBXL7,NFIA,LIFR,NHSL1,DTNA,NRG3,ABLIM1,ITPR2,BMPR1B,TRPS1,NPAS3,PCDH9,SLC1A3,LSAMP,PARD3B,GLIS3,SPARCL1,SLC1A2,PITPNC1,NKAIN3,NTRK2,NEBL,RYR3,PTPRZ1,CTNND2,DCLK2,ADCY2,GPM6A,PPP2R2B,RFX4,LRIG1,CSGALNACT1,NTM,SASH1,RORA,SOX5,ZBTB20,QKI,CDH20,GPC5,MAML2,PRKG1,ATP13A4,MACF1,SORBS1 |
1.443e-09 | -20.36 | acute_lymphoblastic_B_cell_leukaemia | COSMIC cancer mutations | acute_lymphoblastic_B_cell_leukaemia | 3828 | 31 | 16828 | 49 |
CSGALNACT1,BMPR1B,ITPR2,SOX5,ZBTB20,RORA,SASH1,SLC1A3,LSAMP,NTM,PCDH9,FBXL7,LIFR,NFIA,MGAT4C,NRG3,PPP2R2B,GPM6A,ADCY2,ATP13A4,NEBL,RYR3,PRKG1,CTNND2,PTPRZ1,NKAIN3,SLC1A2,GPC5,GLIS3,MAML2,NTRK2 |
1.443e-09 | -20.36 | haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-acute_lymphoblastic_B_cell_leukaemia | COSMIC cancer mutations | haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-acute_lymphoblastic_B_cell_leukaemia | 3828 | 31 | 16828 | 49 |
BMPR1B,ITPR2,CSGALNACT1,SASH1,LSAMP,SLC1A3,PCDH9,NTM,SOX5,ZBTB20,RORA,MGAT4C,FBXL7,NFIA,LIFR,ADCY2,NRG3,GPM6A,PPP2R2B,PRKG1,NEBL,ATP13A4,RYR3,PTPRZ1,CTNND2,SLC1A2,GPC5,GLIS3,NKAIN3,MAML2,NTRK2 |
2.096e-09 | -19.98 | diffuse_large_B_cell_lymphoma | COSMIC cancer mutations | diffuse_large_B_cell_lymphoma | 4151 | 32 | 16828 | 49 |
NTRK2,MAML2,AQP4,CDH20,QKI,SPARCL1,GPC5,SLC1A2,NKAIN3,CTNND2,PRKG1,RYR3,NEBL,ATP13A4,MACF1,ADCY2,DTNA,GPM6A,PPP2R2B,NRG3,LIFR,FBXL7,PCDH9,LSAMP,SLC1A3,SASH1,RORA,SOX5,ITPR2,TRPS1,CSGALNACT1,ATP1A2 |
2.547e-09 | -19.79 | cerebellum | COSMIC cancer mutations | cerebellum | 769 | 15 | 16828 | 49 |
MAML2,ABLIM1,NRG3,NTRK2,GPC5,QKI,PARD3B,PCDH9,NPAS3,PTPRZ1,CTNND2,PRKG1,ITPR2,RYR3,NEBL |
4.492e-09 | -19.22 | central_nervous_system-brain-primitive_neuroectodermal_tumour-medulloblastoma | COSMIC cancer mutations | central_nervous_system-brain-primitive_neuroectodermal_tumour-medulloblastoma | 7205 | 41 | 16828 | 49 |
PITPNC1,NKAIN3,GPC5,SLC1A2,PARD3B,GLIS3,QKI,MAML2,NTRK2,MACF1,ATP13A4,NEBL,RYR3,PRKG1,CTNND2,SORBS1,PTPRZ1,FBXL7,LIFR,NFIA,RFX4,NRG3,ABLIM1,GPM6A,PPP2R2B,ADCY2,NHSL1,DCLK2,TRPS1,CSGALNACT1,LRIG1,ITPR2,ZBTB20,SOX5,RORA,SASH1,LSAMP,SLC1A3,PCDH9,NTM,NPAS3 |
8.164e-09 | -18.62 | mantle_cell_lymphoma | COSMIC cancer mutations | mantle_cell_lymphoma | 2849 | 26 | 16828 | 49 |
PPP2R2B,GPM6A,NRG3,RFX4,ADCY2,FBXL7,LIFR,SOX5,PCDH9,SASH1,LSAMP,SLC1A3,LRIG1,TRPS1,ITPR2,NTRK2,MAML2,NKAIN3,PARD3B,GPC5,SLC1A2,CTNND2,NEBL,ATP13A4,RYR3,PRKG1 |
1.540e-08 | -17.99 | nervous system development | biological process | GO:0007399 | 2185 | 22 | 18204 | 50 |
NRG3,SLC1A3,GPM6A,NTRK2,SOX5,LSAMP,PTPRZ1,RFX4,NTM,DCLK2,BMPR1B,RORA,PRKG1,ATP1A2,PCDH9,CTNND2,SLC1A2,MSI2,CTNNA2,LRIG1,QKI,NFIA |
1.793e-08 | -17.84 | haematopoietic_and_lymphoid_tissue-haematopoietic_neoplasm-acute_myeloid_leukaemia_therapy_related | COSMIC cancer mutations | haematopoietic_and_lymphoid_tissue-haematopoietic_neoplasm-acute_myeloid_leukaemia_therapy_related | 1523 | 19 | 16828 | 49 |
RORA,CTNND2,SOX5,PCDH9,SLC1A3,LSAMP,RYR3,NEBL,ITPR2,PRKG1,PPP2R2B,NTRK2,MAML2,NRG3,ADCY2,NKAIN3,FBXL7,QKI,GPC5 |
1.793e-08 | -17.84 | acute_myeloid_leukaemia_therapy_related | COSMIC cancer mutations | acute_myeloid_leukaemia_therapy_related | 1523 | 19 | 16828 | 49 |
ITPR2,PRKG1,NEBL,RYR3,PCDH9,LSAMP,SLC1A3,RORA,SOX5,CTNND2,QKI,GPC5,FBXL7,NKAIN3,ADCY2,NTRK2,PPP2R2B,NRG3,MAML2 |
1.947e-08 | -17.75 | haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-mantle_cell_lymphoma | COSMIC cancer mutations | haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-mantle_cell_lymphoma | 2737 | 25 | 16828 | 49 |
LIFR,FBXL7,ADCY2,RFX4,NRG3,GPM6A,PPP2R2B,ITPR2,TRPS1,LRIG1,LSAMP,SLC1A3,SASH1,PCDH9,SOX5,GPC5,SLC1A2,PARD3B,NKAIN3,MAML2,NTRK2,PRKG1,RYR3,NEBL,CTNND2 |
2.195e-08 | -17.63 | central_nervous_system-brainstem-glioma-astrocytoma_Grade_IV | COSMIC cancer mutations | central_nervous_system-brainstem-glioma-astrocytoma_Grade_IV | 2531 | 24 | 16828 | 49 |
GPM6A,PPP2R2B,NRG3,ADCY2,FBXL7,LIFR,RORA,SOX5,ZBTB20,PCDH9,SASH1,LSAMP,SLC1A3,ITPR2,MAML2,NKAIN3,CDH20,QKI,GPC5,CTNND2,PTPRZ1,ATP13A4,RYR3,PRKG1 |
2.907e-08 | -17.35 | central_nervous_system-cerebellum-primitive_neuroectodermal_tumour-medulloblastoma-SHH_subtype | COSMIC cancer mutations | central_nervous_system-cerebellum-primitive_neuroectodermal_tumour-medulloblastoma-SHH_subtype | 653 | 13 | 16828 | 49 |
CTNND2,NPAS3,PTPRZ1,PCDH9,NEBL,RYR3,ITPR2,PRKG1,NTRK2,NRG3,ABLIM1,MAML2,PARD3B |
2.915e-08 | -17.35 | chondroblastoma | COSMIC cancer mutations | chondroblastoma | 534 | 12 | 16828 | 49 |
CTNND2,SOX5,LSAMP,PCDH9,RYR3,PRKG1,NRG3,PPP2R2B,GPM6A,ADCY2,NKAIN3,GPC5 |
2.960e-08 | -17.34 | SHH_subtype | COSMIC cancer mutations | SHH_subtype | 654 | 13 | 16828 | 49 |
NRG3,ABLIM1,MAML2,NTRK2,PARD3B,PCDH9,NPAS3,PTPRZ1,CTNND2,PRKG1,ITPR2,NEBL,RYR3 |
4.380e-08 | -16.94 | soft_tissue-blood_vessel-angiosarcoma | COSMIC cancer mutations | soft_tissue-blood_vessel-angiosarcoma | 2192 | 22 | 16828 | 49 |
PCDH9,PTPRZ1,SASH1,LSAMP,SLC1A3,CTNND2,SOX5,ITPR2,PRKG1,NEBL,RYR3,ADCY2,NTRK2,GPM6A,PPP2R2B,NRG3,MAML2,CDH20,SLC1A2,GPC5,FBXL7,NKAIN3 |
4.380e-08 | -16.94 | angiosarcoma | COSMIC cancer mutations | angiosarcoma | 2192 | 22 | 16828 | 49 |
NKAIN3,FBXL7,SLC1A2,GPC5,CDH20,MAML2,NRG3,GPM6A,PPP2R2B,NTRK2,ADCY2,RYR3,NEBL,PRKG1,ITPR2,CTNND2,SOX5,LSAMP,SLC1A3,SASH1,PTPRZ1,PCDH9 |
5.055e-08 | -16.80 | brainstem | COSMIC cancer mutations | brainstem | 3102 | 26 | 16828 | 49 |
LIFR,FBXL7,NRG3,GPM6A,PPP2R2B,ADCY2,ITPR2,ZBTB20,SOX5,RORA,SLC1A3,LSAMP,SASH1,NPAS3,PCDH9,NKAIN3,SLC1A2,GPC5,QKI,CDH20,MAML2,RYR3,ATP13A4,PRKG1,CTNND2,PTPRZ1 |
5.128e-08 | -16.79 | blood_vessel | COSMIC cancer mutations | blood_vessel | 2211 | 22 | 16828 | 49 |
NTRK2,MAML2,CDH20,SLC1A2,GPC5,NKAIN3,PTPRZ1,CTNND2,PRKG1,RYR3,NEBL,ADCY2,GPM6A,PPP2R2B,NRG3,FBXL7,PCDH9,SLC1A3,LSAMP,SASH1,SOX5,ITPR2 |
5.448e-08 | -16.73 | haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-diffuse_large_B_cell_lymphoma | COSMIC cancer mutations | haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-diffuse_large_B_cell_lymphoma | 3608 | 28 | 16828 | 49 |
FBXL7,LIFR,GPM6A,PPP2R2B,NRG3,ADCY2,ATP1A2,CSGALNACT1,ITPR2,RORA,SOX5,PCDH9,SASH1,LSAMP,NKAIN3,SPARCL1,CDH20,QKI,SLC1A2,GPC5,AQP4,MAML2,ATP13A4,NEBL,RYR3,MACF1,PRKG1,CTNND2 |
7.535e-08 | -16.40 | PRNP (prion protein (Kanno blood group)) | protein interactions | 5621 | 1118 | 15 | 19454 | 50 |
ATP1A2,MACF1,GPM6A,PTPRZ1,AQP4,MAML2,NHSL1,LSAMP,MSI2,SLC1A3,SPARCL1,TRPS1,QKI,SORBS1,ABLIM1 |
1.086e-07 | -16.04 | lymph_node | COSMIC cancer mutations | lymph_node | 1703 | 19 | 16828 | 49 |
NRG3,MAML2,NTRK2,GPM6A,DTNA,LIFR,GPC5,PARD3B,CTNND2,SOX5,SLC1A3,LSAMP,PCDH9,TRPS1,NEBL,ATP13A4,RYR3,PRKG1,ITPR2 |
1.593e-07 | -15.65 | lymphoid_neoplasm | COSMIC cancer mutations | lymphoid_neoplasm | 12233 | 49 | 16828 | 49 |
PITPNC1,NKAIN3,GLIS3,SPARCL1,PARD3B,SLC1A2,NTRK2,NEBL,RYR3,CTNND2,PTPRZ1,FBXL7,LIFR,NFIA,MSI2,NRG3,ABLIM1,NHSL1,DTNA,TRPS1,ITPR2,BMPR1B,PCDH9,NPAS3,SLC1A3,LSAMP,QKI,CDH20,GPC5,AQP4,MAML2,ATP13A4,MACF1,PRKG1,SORBS1,MGAT4C,PPP2R2B,GPM6A,RFX4,DCLK2,ADCY2,LRIG1,ATP1A2,CSGALNACT1,RORA,SOX5,ZBTB20,NTM,SASH1 |
1.813e-07 | -15.52 | haematopoietic_and_lymphoid_tissue-haematopoietic_neoplasm | COSMIC cancer mutations | haematopoietic_and_lymphoid_tissue-haematopoietic_neoplasm | 764 | 13 | 16828 | 49 |
ATP1A2,RYR3,LSAMP,PCDH9,SOX5,SLC1A2,GPC5,NKAIN3,FBXL7,ADCY2,MAML2,NRG3,NTRK2 |
2.559e-07 | -15.18 | upper_aerodigestive_tract-mouth-carcinoma-squamous_cell_carcinoma | COSMIC cancer mutations | upper_aerodigestive_tract-mouth-carcinoma-squamous_cell_carcinoma | 6953 | 38 | 16828 | 49 |
MAML2,PITPNC1,GPC5,SLC1A2,CDH20,QKI,PARD3B,CTNND2,SORBS1,PTPRZ1,MACF1,RYR3,ATP13A4,NEBL,PRKG1,ABLIM1,RFX4,NRG3,GPM6A,PPP2R2B,DTNA,ADCY2,DCLK2,NHSL1,FBXL7,MGAT4C,ZBTB20,SOX5,RORA,LSAMP,SASH1,PCDH9,NTM,CSGALNACT1,TRPS1,ATP1A2,LRIG1,ITPR2 |
2.865e-07 | -15.07 | central nervous system development | biological process | GO:0007417 | 995 | 14 | 18204 | 50 |
QKI,MSI2,CTNNA2,ATP1A2,PCDH9,SLC1A2,PRKG1,RORA,RFX4,DCLK2,BMPR1B,PTPRZ1,NRG3,NTRK2 |
6.811e-07 | -14.20 | haematopoietic_and_lymphoid_tissue-haematopoietic_neoplasm-myelodysplastic_syndrome | COSMIC cancer mutations | haematopoietic_and_lymphoid_tissue-haematopoietic_neoplasm-myelodysplastic_syndrome | 1174 | 15 | 16828 | 49 |
ATP1A2,RYR3,PRKG1,BMPR1B,SOX5,LSAMP,NPAS3,NFIA,NKAIN3,FBXL7,SLC1A2,NRG3,NTRK2,DCLK2,ADCY2 |
6.811e-07 | -14.20 | myelodysplastic_syndrome | COSMIC cancer mutations | myelodysplastic_syndrome | 1174 | 15 | 16828 | 49 |
LSAMP,NPAS3,SOX5,BMPR1B,PRKG1,ATP1A2,RYR3,ADCY2,DCLK2,NRG3,NTRK2,SLC1A2,FBXL7,NFIA,NKAIN3 |
9.113e-07 | -13.91 | haematopoietic_and_lymphoid_tissue-lymph_node-lymphoid_neoplasm-mantle_cell_lymphoma | COSMIC cancer mutations | haematopoietic_and_lymphoid_tissue-lymph_node-lymphoid_neoplasm-mantle_cell_lymphoma | 476 | 10 | 16828 | 49 |
MAML2,NRG3,CTNND2,GPM6A,LSAMP,PCDH9,RYR3,ATP13A4,PRKG1,GPC5 |
1.129e-06 | -13.69 | system development | biological process | GO:0048731 | 3533 | 25 | 18204 | 50 |
PCDH9,ATP1A2,CTNNA2,QKI,NFIA,NEBL,SOX5,NTRK2,TRPS1,PTPRZ1,NTM,BMPR1B,PRKG1,RORA,SLC1A2,CTNND2,MSI2,CSGALNACT1,LRIG1,NRG3,GPM6A,SLC1A3,LSAMP,RFX4,DCLK2 |
1.623e-06 | -13.33 | CTNNA1 (catenin alpha 1) | protein interactions | 1495 | 325 | 8 | 19454 | 50 |
MACF1,CTNNA2,SASH1,NHSL1,DTNA,ABLIM1,SORBS1,NEBL |
1.873e-06 | -13.19 | mouth | COSMIC cancer mutations | mouth | 9004 | 42 | 16828 | 49 |
MGAT4C,LIFR,FBXL7,DTNA,DCLK2,ADCY2,NHSL1,ABLIM1,RFX4,NRG3,GPM6A,PPP2R2B,ITPR2,TRPS1,CSGALNACT1,ATP1A2,LRIG1,LSAMP,SLC1A3,SASH1,NPAS3,NTM,PCDH9,SOX5,ZBTB20,RORA,GPC5,SLC1A2,CDH20,QKI,PARD3B,PITPNC1,MAML2,NTRK2,PRKG1,MACF1,RYR3,ATP13A4,NEBL,SORBS1,PTPRZ1,CTNND2 |
2.521e-06 | -12.89 | multicellular organism development | biological process | GO:0007275 | 3957 | 26 | 18204 | 50 |
MSI2,CTNND2,SLC1A2,CSGALNACT1,LRIG1,LSAMP,GPM6A,SLC1A3,NRG3,DCLK2,RFX4,CTNNA2,ATP1A2,PCDH9,CDH20,NFIA,QKI,PTPRZ1,TRPS1,NTRK2,SOX5,NEBL,PRKG1,RORA,BMPR1B,NTM |
3.019e-06 | -12.71 | soft_tissue | COSMIC cancer mutations | soft_tissue | 5828 | 33 | 16828 | 49 |
GPM6A,PPP2R2B,NRG3,ADCY2,NHSL1,FBXL7,NFIA,RORA,SOX5,PCDH9,NPAS3,SASH1,SLC1A3,LSAMP,TRPS1,ITPR2,NTRK2,AQP4,MAML2,NKAIN3,GLIS3,SPARCL1,PARD3B,CDH20,SLC1A2,GPC5,CTNND2,PTPRZ1,SORBS1,NEBL,RYR3,MACF1,PRKG1 |
3.540e-06 | -12.55 | trunk | COSMIC cancer mutations | trunk | 3554 | 25 | 16828 | 49 |
MAML2,NTRK2,GLIS3,SPARCL1,CDH20,CTNND2,PTPRZ1,MACF1,ATP13A4,NEBL,RYR3,NRG3,ABLIM1,PPP2R2B,DCLK2,LIFR,MGAT4C,SOX5,SASH1,LSAMP,SLC1A3,PCDH9,NPAS3,ATP1A2,TRPS1 |
3.650e-06 | -12.52 | MAPT (microtubule associated protein tau) | protein interactions | 4137 | 948 | 12 | 19454 | 50 |
SORBS1,ABLIM1,NEBL,CTNNA2,CTNND2,SLC1A3,SLC1A2,NTM,LSAMP,PPP2R2B,GPM6A,ATP1A2 |
4.959e-06 | -12.21 | haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm | COSMIC cancer mutations | haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm | 7307 | 37 | 16828 | 49 |
RORA,SOX5,PCDH9,SASH1,LSAMP,SLC1A3,LRIG1,CSGALNACT1,ITPR2,BMPR1B,GPM6A,PPP2R2B,NRG3,RFX4,ABLIM1,ADCY2,NHSL1,FBXL7,LIFR,MGAT4C,CTNND2,PTPRZ1,ATP13A4,NEBL,RYR3,MACF1,PRKG1,NTRK2,MAML2,NKAIN3,SPARCL1,PARD3B,GLIS3,CDH20,QKI,GPC5,SLC1A2 |
6.238e-06 | -11.98 | Salivary secretion | KEGG pathways | ko04970 | 90 | 5 | 7161 | 22 |
ADCY2,ITPR2,RYR3,ATP1A2,PRKG1 |
6.238e-06 | -11.98 | Salivary secretion | KEGG pathways | hsa04970 | 90 | 5 | 7161 | 22 |
ATP1A2,PRKG1,ADCY2,ITPR2,RYR3 |
8.577e-06 | -11.67 | oesophagus-carcinoma | COSMIC cancer mutations | oesophagus-carcinoma | 4269 | 27 | 16828 | 49 |
NTM,PCDH9,SOX5,ZBTB20,ITPR2,CSGALNACT1,TRPS1,LRIG1,NHSL1,ADCY2,RFX4,NRG3,GPM6A,PPP2R2B,NFIA,LIFR,FBXL7,SORBS1,PTPRZ1,CTNND2,PRKG1,MACF1,RYR3,ATP13A4,NTRK2,CDH20,PARD3B |
9.205e-06 | -11.60 | neurogenesis | biological process | GO:0022008 | 1334 | 14 | 18204 | 50 |
PRKG1,RORA,DCLK2,BMPR1B,NTM,PTPRZ1,GPM6A,SOX5,NTRK2,SLC1A3,NFIA,QKI,CTNNA2,CTNND2 |
1.014e-05 | -11.50 | generation of neurons | biological process | GO:0048699 | 1158 | 13 | 18204 | 50 |
PRKG1,RORA,NFIA,DCLK2,BMPR1B,NTM,CTNNA2,PTPRZ1,CTNND2,SLC1A3,GPM6A,NTRK2,SOX5 |
1.294e-05 | -11.26 | anatomical structure morphogenesis | biological process | GO:0009653 | 2225 | 18 | 18204 | 50 |
CDH20,NFIA,CSGALNACT1,QKI,LRIG1,CTNNA2,CTNND2,PRKG1,RORA,BMPR1B,PTPRZ1,NEBL,NRG3,GPM6A,NTRK2,SLC1A3,SOX5,ABLIM1 |
1.400e-05 | -11.18 | forebrain development | biological process | GO:0030900 | 408 | 8 | 18204 | 50 |
DCLK2,RFX4,PRKG1,NTRK2,SLC1A2,ATP1A2,NRG3,PCDH9 |
1.412e-05 | -11.17 | intestinal_adenocarcinoma | COSMIC cancer mutations | intestinal_adenocarcinoma | 7225 | 36 | 16828 | 49 |
PARD3B,QKI,CDH20,SLC1A2,PITPNC1,NTRK2,AQP4,MAML2,PRKG1,ATP13A4,NEBL,RYR3,MACF1,PTPRZ1,CTNND2,FBXL7,LIFR,NFIA,NHSL1,DCLK2,ADCY2,RFX4,NRG3,ITPR2,LRIG1,ATP1A2,TRPS1,CSGALNACT1,NPAS3,NTM,PCDH9,SASH1,LSAMP,RORA,SOX5,ZBTB20 |
1.412e-05 | -11.17 | stomach-carcinoma-intestinal_adenocarcinoma | COSMIC cancer mutations | stomach-carcinoma-intestinal_adenocarcinoma | 7225 | 36 | 16828 | 49 |
LSAMP,SASH1,NPAS3,PCDH9,NTM,ZBTB20,SOX5,RORA,ITPR2,TRPS1,CSGALNACT1,ATP1A2,LRIG1,ADCY2,NHSL1,DCLK2,RFX4,NRG3,NFIA,LIFR,FBXL7,PTPRZ1,CTNND2,PRKG1,MACF1,RYR3,ATP13A4,NEBL,MAML2,AQP4,NTRK2,SLC1A2,CDH20,QKI,PARD3B,PITPNC1 |
1.786e-05 | -10.93 | haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-follicular_lymphoma | COSMIC cancer mutations | haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-follicular_lymphoma | 981 | 12 | 16828 | 49 |
NRG3,ADCY2,NKAIN3,GPC5,CTNND2,SOX5,RORA,LSAMP,SASH1,PCDH9,PRKG1,ITPR2 |
2.057e-05 | -10.79 | cell junction | cellular component | GO:0030054 | 2224 | 17 | 19108 | 49 |
CTNND2,NTRK2,PCDH9,NRG3,ATP1A2,QKI,PTPRZ1,SORBS1,CTNNA2,SPARCL1,PARD3B,SLC1A2,DTNA,CDH20,SLC1A3,NFIA,GPM6A |
2.258e-05 | -10.70 | brain development | biological process | GO:0007420 | 724 | 10 | 18204 | 50 |
RORA,PRKG1,RFX4,DCLK2,CTNNA2,ATP1A2,NRG3,PCDH9,SLC1A2,NTRK2 |
2.353e-05 | -10.66 | lung-right_lower_lobe-carcinoma-adenocarcinoma | COSMIC cancer mutations | lung-right_lower_lobe-carcinoma-adenocarcinoma | 5692 | 31 | 16828 | 49 |
SORBS1,PTPRZ1,CTNND2,PRKG1,MACF1,RYR3,NEBL,ATP13A4,MAML2,NTRK2,GPC5,CDH20,PARD3B,NKAIN3,LSAMP,SLC1A3,NTM,NPAS3,SOX5,ITPR2,TRPS1,ATP1A2,LRIG1,DTNA,ADCY2,NRG3,GPM6A,PPP2R2B,MGAT4C,LIFR,FBXL7 |
2.353e-05 | -10.66 | right_lower_lobe | COSMIC cancer mutations | right_lower_lobe | 5692 | 31 | 16828 | 49 |
MAML2,NTRK2,GPC5,PARD3B,CDH20,NKAIN3,SORBS1,PTPRZ1,CTNND2,PRKG1,MACF1,NEBL,ATP13A4,RYR3,DTNA,ADCY2,NRG3,GPM6A,PPP2R2B,MGAT4C,FBXL7,LIFR,SLC1A3,LSAMP,NTM,NPAS3,SOX5,ITPR2,ATP1A2,TRPS1,LRIG1 |
2.407e-05 | -10.63 | humerus | COSMIC cancer mutations | humerus | 546 | 9 | 16828 | 49 |
GPC5,PRKG1,PARD3B,NKAIN3,NEBL,ADCY2,SOX5,PPP2R2B,GPM6A |
2.465e-05 | -10.61 | bone-humerus-other-chondroblastoma | COSMIC cancer mutations | bone-humerus-other-chondroblastoma | 301 | 7 | 16828 | 49 |
PRKG1,GPC5,NKAIN3,ADCY2,SOX5,PPP2R2B,GPM6A |
2.586e-05 | -10.56 | carcinoid-endocrine_tumour | COSMIC cancer mutations | carcinoid-endocrine_tumour | 7752 | 37 | 16828 | 49 |
MAML2,NTRK2,GPC5,SLC1A2,GLIS3,QKI,CDH20,NKAIN3,PTPRZ1,CTNND2,PRKG1,MACF1,ATP13A4,NEBL,RYR3,NHSL1,ADCY2,DCLK2,RFX4,NRG3,ABLIM1,GPM6A,PPP2R2B,FBXL7,LIFR,SASH1,SLC1A3,LSAMP,PCDH9,SOX5,RORA,BMPR1B,ITPR2,ATP1A2,TRPS1,CSGALNACT1,LRIG1 |
2.682e-05 | -10.53 | neuron differentiation | biological process | GO:0030182 | 1081 | 12 | 18204 | 50 |
CTNNA2,CTNND2,NFIA,PTPRZ1,SLC1A3,GPM6A,NTRK2,RORA,PRKG1,NTM,BMPR1B,DCLK2 |
2.893e-05 | -10.45 | pharynx | COSMIC cancer mutations | pharynx | 2696 | 20 | 16828 | 49 |
NFIA,PITPNC1,QKI,PARD3B,SLC1A2,GPC5,NTRK2,RFX4,NRG3,NHSL1,DTNA,RYR3,ATP13A4,MACF1,ATP1A2,CTNND2,NPAS3,PCDH9,PTPRZ1,SORBS1 |
2.915e-05 | -10.44 | follicular_lymphoma | COSMIC cancer mutations | follicular_lymphoma | 1209 | 13 | 16828 | 49 |
PRKG1,ITPR2,CTNND2,SOX5,RORA,SASH1,LSAMP,PCDH9,NKAIN3,GPC5,NRG3,AQP4,ADCY2 |
3.096e-05 | -10.38 | sarcolemma | cellular component | GO:0042383 | 142 | 5 | 19108 | 49 |
DTNA,ATP1A2,PRKG1,AQP4,RYR3 |
3.520e-05 | -10.25 | plasma membrane | cellular component | GO:0005886 | 5538 | 28 | 19108 | 49 |
GPM6A,LRIG1,ITPR2,SLC1A3,BMPR1B,SLC1A2,ADCY2,PTPRZ1,LIFR,NTM,AQP4,ATP1A2,MACF1,GPC5,CDH20,DTNA,PARD3B,ATP13A4,NKAIN3,CTNNA2,SORBS1,PRKG1,LSAMP,RYR3,PCDH9,NRG3,CTNND2,NTRK2 |
3.991e-05 | -10.13 | head development | biological process | GO:0060322 | 774 | 10 | 18204 | 50 |
CTNNA2,PCDH9,NRG3,ATP1A2,SLC1A2,NTRK2,RORA,PRKG1,RFX4,DCLK2 |
4.105e-05 | -10.10 | oesophagus-carcinoma-squamous_cell_carcinoma | COSMIC cancer mutations | oesophagus-carcinoma-squamous_cell_carcinoma | 6486 | 33 | 16828 | 49 |
AQP4,MAML2,PITPNC1,SPARCL1,GLIS3,PARD3B,GPC5,CTNND2,PTPRZ1,SORBS1,NEBL,ATP13A4,RYR3,MACF1,PRKG1,GPM6A,NRG3,ABLIM1,DCLK2,ADCY2,FBXL7,LIFR,MGAT4C,ZBTB20,SOX5,PCDH9,NPAS3,SASH1,ATP1A2,CSGALNACT1,TRPS1,ITPR2,BMPR1B |
4.274e-05 | -10.06 | Neurotransmitter uptake and Metabolism In Glial Cells | REACTOME pathways | R-HSA-112313 | 4 | 2 | 10285 | 28 |
SLC1A3,SLC1A2 |
4.274e-05 | -10.06 | Astrocytic Glutamate-Glutamine Uptake And Metabolism | REACTOME pathways | R-HSA-210455 | 4 | 2 | 10285 | 28 |
SLC1A2,SLC1A3 |
4.392e-05 | -10.03 | cervix-carcinoma-squamous_cell_carcinoma | COSMIC cancer mutations | cervix-carcinoma-squamous_cell_carcinoma | 11789 | 46 | 16828 | 49 |
NTM,SASH1,RORA,ZBTB20,SOX5,LRIG1,ATP1A2,CSGALNACT1,ADCY2,DCLK2,GPM6A,PPP2R2B,RFX4,MGAT4C,SORBS1,PRKG1,ATP13A4,MACF1,MAML2,CDH20,QKI,GPC5,PCDH9,NPAS3,SLC1A3,LSAMP,ITPR2,BMPR1B,TRPS1,NHSL1,DTNA,NRG3,ABLIM1,FBXL7,LIFR,NFIA,PTPRZ1,CTNND2,NEBL,RYR3,NTRK2,SPARCL1,PARD3B,GLIS3,SLC1A2,PITPNC1 |
4.451e-05 | -10.02 | cervix | COSMIC cancer mutations | cervix | 11793 | 46 | 16828 | 49 |
SLC1A2,PARD3B,GLIS3,SPARCL1,PITPNC1,NTRK2,RYR3,NEBL,PTPRZ1,CTNND2,NFIA,LIFR,FBXL7,DTNA,NHSL1,ABLIM1,NRG3,BMPR1B,ITPR2,TRPS1,LSAMP,SLC1A3,NPAS3,PCDH9,GPC5,QKI,CDH20,MAML2,PRKG1,MACF1,ATP13A4,SORBS1,MGAT4C,ADCY2,DCLK2,RFX4,GPM6A,PPP2R2B,CSGALNACT1,ATP1A2,LRIG1,SASH1,NTM,ZBTB20,SOX5,RORA |
4.464e-05 | -10.02 | anatomical structure development | biological process | GO:0048856 | 5207 | 28 | 18204 | 50 |
RFX4,DCLK2,LSAMP,NRG3,ABLIM1,GPM6A,SLC1A3,CSGALNACT1,LRIG1,MSI2,SLC1A2,CTNND2,PRKG1,RORA,SPARCL1,NTM,BMPR1B,PTPRZ1,TRPS1,NEBL,NTRK2,SOX5,NFIA,CDH20,QKI,CTNNA2,PCDH9,ATP1A2 |
5.135e-05 | -9.88 | lung-right_upper_lobe-carcinoma-adenocarcinoma | COSMIC cancer mutations | lung-right_upper_lobe-carcinoma-adenocarcinoma | 10376 | 43 | 16828 | 49 |
ATP13A4,MACF1,PRKG1,SORBS1,CDH20,GPC5,LRIG1,ATP1A2,CSGALNACT1,RORA,ZBTB20,SOX5,NTM,SASH1,MGAT4C,GPM6A,PPP2R2B,RFX4,DCLK2,ADCY2,NEBL,RYR3,CTNND2,PTPRZ1,NKAIN3,PITPNC1,GLIS3,PARD3B,SLC1A2,NTRK2,TRPS1,ITPR2,BMPR1B,NPAS3,PCDH9,SLC1A3,LSAMP,FBXL7,NFIA,LIFR,NRG3,ABLIM1,DTNA |
5.135e-05 | -9.88 | right_upper_lobe | COSMIC cancer mutations | right_upper_lobe | 10376 | 43 | 16828 | 49 |
CDH20,GPC5,PRKG1,ATP13A4,MACF1,SORBS1,MGAT4C,ADCY2,DCLK2,GPM6A,PPP2R2B,RFX4,LRIG1,CSGALNACT1,ATP1A2,NTM,SASH1,RORA,SOX5,ZBTB20,PARD3B,GLIS3,SLC1A2,NKAIN3,PITPNC1,NTRK2,RYR3,NEBL,PTPRZ1,CTNND2,LIFR,NFIA,FBXL7,DTNA,ABLIM1,NRG3,ITPR2,BMPR1B,TRPS1,PCDH9,NPAS3,LSAMP,SLC1A3 |
5.769e-05 | -9.76 | cell periphery | cellular component | GO:0071944 | 6020 | 29 | 19108 | 49 |
NKAIN3,ATP13A4,LSAMP,CTNNA2,SORBS1,PRKG1,NRG3,PCDH9,CTNND2,NTRK2,RYR3,GPC5,DTNA,CDH20,PARD3B,SPARCL1,PTPRZ1,LIFR,NTM,MACF1,AQP4,ATP1A2,ITPR2,SLC1A3,GPM6A,LRIG1,SLC1A2,BMPR1B,ADCY2 |
5.783e-05 | -9.76 | skin-trunk-malignant_melanoma-nodular | COSMIC cancer mutations | skin-trunk-malignant_melanoma-nodular | 1291 | 13 | 16828 | 49 |
ATP1A2,MACF1,ATP13A4,NEBL,SPARCL1,GLIS3,CDH20,CTNND2,ABLIM1,NTRK2,DCLK2,PTPRZ1,NPAS3 |
6.856e-05 | -9.59 | high-affinity L-glutamate transmembrane transporter activity | molecular function | GO:0005314 | 5 | 2 | 18094 | 48 |
SLC1A2,SLC1A3 |
6.856e-05 | -9.59 | glutamate:sodium symporter activity | molecular function | GO:0015501 | 5 | 2 | 18094 | 48 |
SLC1A2,SLC1A3 |
7.355e-05 | -9.52 | D-aspartate import across plasma membrane | biological process | GO:0070779 | 5 | 2 | 18204 | 50 |
SLC1A3,SLC1A2 |
7.355e-05 | -9.52 | D-aspartate transmembrane transport | biological process | GO:0070777 | 5 | 2 | 18204 | 50 |
SLC1A2,SLC1A3 |
7.513e-05 | -9.50 | neurotransmitter uptake | biological process | GO:0001504 | 30 | 3 | 18204 | 50 |
SLC1A2,SLC1A3,ATP1A2 |
7.933e-05 | -9.44 | mast_cell_neoplasm | COSMIC cancer mutations | mast_cell_neoplasm | 248 | 6 | 16828 | 49 |
GPC5,NFIA,PCDH9,NPAS3,ADCY2,NRG3 |
7.933e-05 | -9.44 | haematopoietic_and_lymphoid_tissue-haematopoietic_neoplasm-mast_cell_neoplasm | COSMIC cancer mutations | haematopoietic_and_lymphoid_tissue-haematopoietic_neoplasm-mast_cell_neoplasm | 248 | 6 | 16828 | 49 |
NRG3,NFIA,ADCY2,PCDH9,NPAS3,GPC5 |
7.937e-05 | -9.44 | prostate | COSMIC cancer mutations | prostate | 13883 | 49 | 16828 | 49 |
AQP4,MAML2,GPC5,CDH20,QKI,SORBS1,MACF1,ATP13A4,PRKG1,RFX4,GPM6A,PPP2R2B,DCLK2,ADCY2,MGAT4C,ZBTB20,SOX5,RORA,SASH1,NTM,ATP1A2,CSGALNACT1,LRIG1,NTRK2,NKAIN3,PITPNC1,SLC1A2,GLIS3,PARD3B,SPARCL1,CTNND2,PTPRZ1,NEBL,RYR3,NRG3,ABLIM1,DTNA,NHSL1,FBXL7,LIFR,NFIA,MSI2,SLC1A3,LSAMP,NPAS3,PCDH9,TRPS1,BMPR1B,ITPR2 |
8.255e-05 | -9.40 | NTM (neurotrimin) | protein interactions | 50863 | 33 | 3 | 19454 | 50 |
GPM6A,NTM,LSAMP |
8.981e-05 | -9.32 | developmental process | biological process | GO:0032502 | 5716 | 29 | 18204 | 50 |
PRKG1,RORA,NTM,SPARCL1,BMPR1B,TRPS1,PTPRZ1,NEBL,NTRK2,SOX5,CDH20,NFIA,QKI,CTNNA2,ATP1A2,PCDH9,RFX4,DCLK2,LSAMP,NRG3,SLC1A3,GPM6A,ABLIM1,LRIG1,CSGALNACT1,MSI2,NHSL1,CTNND2,SLC1A2 |
9.218e-05 | -9.29 | cell morphogenesis | biological process | GO:0000902 | 687 | 9 | 18204 | 50 |
SLC1A3,GPM6A,CTNND2,PTPRZ1,CTNNA2,BMPR1B,NFIA,CDH20,PRKG1 |
9.559e-05 | -9.26 | neuron development | biological process | GO:0048666 | 859 | 10 | 18204 | 50 |
PTPRZ1,CTNNA2,CTNND2,SLC1A3,NTRK2,GPM6A,PRKG1,DCLK2,BMPR1B,NTM |
1.023e-04 | -9.19 | bone | COSMIC cancer mutations | bone | 8157 | 37 | 16828 | 49 |
NKAIN3,QKI,PARD3B,SPARCL1,GLIS3,GPC5,NTRK2,MAML2,RYR3,NEBL,ATP13A4,MACF1,PRKG1,CTNND2,PTPRZ1,SORBS1,LIFR,GPM6A,PPP2R2B,ABLIM1,NRG3,DCLK2,ADCY2,DTNA,LRIG1,TRPS1,CSGALNACT1,ATP1A2,ITPR2,RORA,ZBTB20,SOX5,PCDH9,NPAS3,SLC1A3,LSAMP,SASH1 |
1.044e-04 | -9.17 | telencephalon development | biological process | GO:0021537 | 276 | 6 | 18204 | 50 |
NTRK2,SLC1A2,DCLK2,NRG3,RFX4,ATP1A2 |
1.061e-04 | -9.15 | RIH_assoc | pfam domains | PF08454 | 6 | 2 | 17795 | 48 |
RYR3,ITPR2 |
1.061e-04 | -9.15 | RYDR_ITPR | pfam domains | PF01365 | 6 | 2 | 17795 | 48 |
RYR3,ITPR2 |
1.061e-04 | -9.15 | Ins145_P3_rec | pfam domains | PF08709 | 6 | 2 | 17795 | 48 |
ITPR2,RYR3 |
1.064e-04 | -9.15 | RIH_assoc-dom | interpro domains | IPR013662 | 6 | 2 | 18521 | 50 |
ITPR2,RYR3 |
1.064e-04 | -9.15 | RIH_dom | interpro domains | IPR000699 | 6 | 2 | 18521 | 50 |
RYR3,ITPR2 |
1.064e-04 | -9.15 | Ryanodine_IP3_receptor | interpro domains | IPR015925 | 6 | 2 | 18521 | 50 |
ITPR2,RYR3 |
1.064e-04 | -9.15 | RyR/IP3R_RIH_dom_sf | interpro domains | IPR035910 | 6 | 2 | 18521 | 50 |
RYR3,ITPR2 |
1.064e-04 | -9.15 | Ins145_P3_rcpt | interpro domains | IPR014821 | 6 | 2 | 18521 | 50 |
RYR3,ITPR2 |
1.080e-04 | -9.13 | autonomic_ganglia | COSMIC cancer mutations | autonomic_ganglia | 4005 | 24 | 16828 | 49 |
SASH1,PCDH9,NPAS3,ATP1A2,TRPS1,RFX4,GPM6A,ADCY2,NHSL1,FBXL7,NFIA,CTNND2,PTPRZ1,MACF1,NEBL,RYR3,PRKG1,AQP4,MAML2,NTRK2,PITPNC1,SLC1A2,GLIS3,PARD3B |
1.101e-04 | -9.11 | L-aspartate import across plasma membrane | biological process | GO:0140009 | 6 | 2 | 18204 | 50 |
SLC1A2,SLC1A3 |
1.101e-04 | -9.11 | D-amino acid transport | biological process | GO:0042940 | 6 | 2 | 18204 | 50 |
SLC1A2,SLC1A3 |
1.173e-04 | -9.05 | adherens junction | cellular component | GO:0005912 | 188 | 5 | 19108 | 49 |
CTNND2,SORBS1,CDH20,CTNNA2,PARD3B |
1.284e-04 | -8.96 | IP3 receptor type 1 binding core, RIH domain | gene3d domains | 1.25.10.30 | 6 | 2 | 14470 | 43 |
RYR3,ITPR2 |
1.317e-04 | -8.94 | skin-face-carcinoma-squamous_cell_carcinoma | COSMIC cancer mutations | skin-face-carcinoma-squamous_cell_carcinoma | 2036 | 16 | 16828 | 49 |
TRPS1,MACF1,CSGALNACT1,NEBL,ITPR2,RORA,LSAMP,PCDH9,PTPRZ1,GPC5,MSI2,NRG3,AQP4,ABLIM1,GPM6A,PPP2R2B |
1.329e-04 | -8.93 | haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-chronic_lymphocytic_leukaemia-small_lymphocytic_lymphoma | COSMIC cancer mutations | haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-chronic_lymphocytic_leukaemia-small_lymphocytic_lymphoma | 3511 | 22 | 16828 | 49 |
BMPR1B,PCDH9,NPAS3,LSAMP,SLC1A3,LIFR,FBXL7,MGAT4C,MSI2,PPP2R2B,NRG3,ADCY2,DTNA,RYR3,MACF1,PRKG1,CTNND2,PTPRZ1,PITPNC1,PARD3B,GPC5,NTRK2 |
1.329e-04 | -8.93 | chronic_lymphocytic_leukaemia-small_lymphocytic_lymphoma | COSMIC cancer mutations | chronic_lymphocytic_leukaemia-small_lymphocytic_lymphoma | 3511 | 22 | 16828 | 49 |
GPC5,MSI2,MGAT4C,PARD3B,FBXL7,PITPNC1,LIFR,DTNA,ADCY2,NRG3,NTRK2,PPP2R2B,BMPR1B,PRKG1,MACF1,RYR3,LSAMP,SLC1A3,NPAS3,PTPRZ1,PCDH9,CTNND2 |
1.412e-04 | -8.87 | multicellular organismal process | biological process | GO:0032501 | 6177 | 30 | 18204 | 50 |
NRG3,GPM6A,ABLIM1,SLC1A3,LSAMP,RFX4,DCLK2,DTNA,CTNND2,SLC1A2,MSI2,LRIG1,CSGALNACT1,NEBL,RYR3,SOX5,NTRK2,TRPS1,PTPRZ1,NTM,BMPR1B,PRKG1,RORA,ATP1A2,PCDH9,AQP4,CTNNA2,QKI,CDH20,NFIA |
1.483e-04 | -8.82 | SDF | pfam domains | PF00375 | 7 | 2 | 17795 | 48 |
SLC1A3,SLC1A2 |
1.487e-04 | -8.81 | Na-dicarboxylate_symporter_CS | interpro domains | IPR018107 | 7 | 2 | 18521 | 50 |
SLC1A3,SLC1A2 |
1.487e-04 | -8.81 | Na-dicarboxylate_symporter | interpro domains | IPR001991 | 7 | 2 | 18521 | 50 |
SLC1A2,SLC1A3 |
1.487e-04 | -8.81 | Na:dicarbo_symporter_sf | interpro domains | IPR036458 | 7 | 2 | 18521 | 50 |
SLC1A3,SLC1A2 |
1.662e-04 | -8.70 | cellular response to alkaloid | biological process | GO:0071312 | 39 | 3 | 18204 | 50 |
SLC1A2,SLC1A3,RYR3 |
1.762e-04 | -8.64 | pancreas-carcinoid-endocrine_tumour | COSMIC cancer mutations | pancreas-carcinoid-endocrine_tumour | 7250 | 34 | 16828 | 49 |
LRIG1,CSGALNACT1,ATP1A2,ITPR2,BMPR1B,RORA,SOX5,PCDH9,SLC1A3,LSAMP,SASH1,LIFR,FBXL7,PPP2R2B,GPM6A,ABLIM1,NRG3,RFX4,ADCY2,NHSL1,RYR3,ATP13A4,NEBL,MACF1,PRKG1,CTNND2,NKAIN3,QKI,CDH20,GLIS3,SLC1A2,GPC5,NTRK2,MAML2 |
1.794e-04 | -8.63 | Sodium:dicarboxylate symporter | gene3d domains | 1.10.3860.10 | 7 | 2 | 14470 | 43 |
SLC1A3,SLC1A2 |
1.810e-04 | -8.62 | lung-carcinoma-small_cell_carcinoma | COSMIC cancer mutations | lung-carcinoma-small_cell_carcinoma | 9908 | 41 | 16828 | 49 |
SORBS1,PTPRZ1,CTNND2,PRKG1,MACF1,ATP13A4,NEBL,RYR3,MAML2,NTRK2,GPC5,PARD3B,SPARCL1,QKI,CDH20,PITPNC1,NKAIN3,SASH1,NTM,PCDH9,NPAS3,SOX5,RORA,BMPR1B,ITPR2,ATP1A2,CSGALNACT1,TRPS1,LRIG1,DTNA,DCLK2,RFX4,NRG3,ABLIM1,PPP2R2B,GPM6A,MSI2,MGAT4C,FBXL7,LIFR,NFIA |
1.838e-04 | -8.60 | small_cell_carcinoma | COSMIC cancer mutations | small_cell_carcinoma | 9913 | 41 | 16828 | 49 |
NTRK2,MAML2,NKAIN3,PITPNC1,CDH20,QKI,SPARCL1,PARD3B,GPC5,CTNND2,PTPRZ1,SORBS1,RYR3,NEBL,ATP13A4,MACF1,PRKG1,PPP2R2B,GPM6A,ABLIM1,RFX4,NRG3,DCLK2,DTNA,NFIA,LIFR,FBXL7,MGAT4C,MSI2,RORA,SOX5,PCDH9,NTM,NPAS3,SASH1,LRIG1,TRPS1,CSGALNACT1,ATP1A2,ITPR2,BMPR1B |
1.841e-04 | -8.60 | beta-catenin binding | molecular function | GO:0008013 | 107 | 4 | 18094 | 48 |
CDH20,RORA,CTNND2,CTNNA2 |
1.843e-04 | -8.60 | lung-left_upper_lobe-carcinoma-adenocarcinoma | COSMIC cancer mutations | lung-left_upper_lobe-carcinoma-adenocarcinoma | 556 | 8 | 16828 | 49 |
PRKG1,FBXL7,LIFR,TRPS1,RYR3,ADCY2,CTNND2,NTRK2 |
1.874e-04 | -8.58 | bone-tibia-other-chondroblastoma | COSMIC cancer mutations | bone-tibia-other-chondroblastoma | 98 | 4 | 16828 | 49 |
LSAMP,GPM6A,NKAIN3,CTNND2 |
1.889e-04 | -8.57 | left_upper_lobe | COSMIC cancer mutations | left_upper_lobe | 558 | 8 | 16828 | 49 |
ADCY2,CTNND2,NTRK2,PRKG1,LIFR,TRPS1,FBXL7,RYR3 |
2.063e-04 | -8.49 | haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-plasma_cell_myeloma | COSMIC cancer mutations | haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-plasma_cell_myeloma | 1263 | 12 | 16828 | 49 |
ADCY2,NTRK2,GPM6A,NRG3,ABLIM1,NTM,CTNND2,ATP13A4,NEBL,RYR3,MACF1,TRPS1 |
2.063e-04 | -8.49 | plasma_cell_myeloma | COSMIC cancer mutations | plasma_cell_myeloma | 1263 | 12 | 16828 | 49 |
MACF1,TRPS1,RYR3,ATP13A4,NEBL,CTNND2,NTM,ABLIM1,NRG3,GPM6A,NTRK2,ADCY2 |
2.304e-04 | -8.38 | NEGR1 (neuronal growth regulator 1) | protein interactions | 257194 | 9 | 2 | 19454 | 50 |
NTM,LSAMP |
2.304e-04 | -8.38 | LSAMP (limbic system associated membrane protein) | protein interactions | 4045 | 9 | 2 | 19454 | 50 |
LSAMP,NTM |
2.355e-04 | -8.35 | face | COSMIC cancer mutations | face | 2139 | 16 | 16828 | 49 |
AQP4,NRG3,ABLIM1,PPP2R2B,GPM6A,GPC5,MSI2,LSAMP,PCDH9,PTPRZ1,RORA,ITPR2,TRPS1,CSGALNACT1,MACF1,NEBL |
2.443e-04 | -8.32 | central_nervous_system-cerebellum-glioma-astrocytoma_Grade_I | COSMIC cancer mutations | central_nervous_system-cerebellum-glioma-astrocytoma_Grade_I | 105 | 4 | 16828 | 49 |
QKI,PRKG1,GPC5,NRG3 |
2.480e-04 | -8.30 | adenoma | COSMIC cancer mutations | adenoma | 2873 | 19 | 16828 | 49 |
GPC5,CDH20,LIFR,DCLK2,ADCY2,GPM6A,NTRK2,PRKG1,BMPR1B,MACF1,RYR3,NEBL,SASH1,NPAS3,PTPRZ1,PCDH9,CTNND2,ZBTB20,SOX5 |
2.526e-04 | -8.28 | NA_DICARBOXYL_SYMP_2 | prosite domains | PS00714 | 7 | 2 | 12186 | 43 |
SLC1A3,SLC1A2 |
2.526e-04 | -8.28 | NA_DICARBOXYL_SYMP_1 | prosite domains | PS00713 | 7 | 2 | 12186 | 43 |
SLC1A3,SLC1A2 |
2.551e-04 | -8.27 | acidic amino acid transport | biological process | GO:0015800 | 45 | 3 | 18204 | 50 |
SLC1A3,SLC1A2,NTRK2 |
2.586e-04 | -8.26 | cellular response to organic cyclic compound | biological process | GO:0071407 | 464 | 7 | 18204 | 50 |
ITPR2,ATP1A2,SLC1A2,SLC1A3,RYR3,ADCY2,RORA |
2.680e-04 | -8.22 | haematopoietic_and_lymphoid_tissue-lymph_node-lymphoid_neoplasm-diffuse_large_B_cell_lymphoma | COSMIC cancer mutations | haematopoietic_and_lymphoid_tissue-lymph_node-lymphoid_neoplasm-diffuse_large_B_cell_lymphoma | 748 | 9 | 16828 | 49 |
SLC1A3,DTNA,SOX5,CTNND2,NTRK2,PRKG1,ITPR2,TRPS1,NEBL |
2.764e-04 | -8.19 | skin-trunk-malignant_melanoma | COSMIC cancer mutations | skin-trunk-malignant_melanoma | 2647 | 18 | 16828 | 49 |
SLC1A3,LSAMP,SASH1,PTPRZ1,PCDH9,SOX5,CTNND2,TRPS1,ATP1A2,RYR3,NEBL,ATP13A4,MAML2,NRG3,PPP2R2B,CDH20,MGAT4C,LIFR |
2.855e-04 | -8.16 | upper_aerodigestive_tract-larynx-carcinoma-squamous_cell_carcinoma | COSMIC cancer mutations | upper_aerodigestive_tract-larynx-carcinoma-squamous_cell_carcinoma | 1946 | 15 | 16828 | 49 |
CSGALNACT1,MACF1,RYR3,NEBL,BMPR1B,ITPR2,ZBTB20,SOX5,RORA,PCDH9,NPAS3,PARD3B,MGAT4C,MAML2,GPM6A |
2.887e-04 | -8.15 | larynx | COSMIC cancer mutations | larynx | 1948 | 15 | 16828 | 49 |
MGAT4C,PARD3B,GPM6A,MAML2,RYR3,NEBL,CSGALNACT1,MACF1,ITPR2,BMPR1B,RORA,SOX5,ZBTB20,PCDH9,NPAS3 |
2.894e-04 | -8.15 | autonomic_ganglia-neuroblastoma | COSMIC cancer mutations | autonomic_ganglia-neuroblastoma | 3970 | 23 | 16828 | 49 |
RYR3,NEBL,TRPS1,MACF1,ATP1A2,PRKG1,CTNND2,NPAS3,PCDH9,PTPRZ1,SASH1,NFIA,PITPNC1,FBXL7,PARD3B,GLIS3,SLC1A2,GPM6A,NTRK2,MAML2,AQP4,RFX4,ADCY2 |
2.905e-04 | -8.14 | neuroblastoma | COSMIC cancer mutations | neuroblastoma | 3971 | 23 | 16828 | 49 |
MACF1,NEBL,RYR3,PRKG1,CTNND2,PTPRZ1,PITPNC1,SLC1A2,GLIS3,PARD3B,AQP4,MAML2,NTRK2,ATP1A2,TRPS1,SASH1,PCDH9,NPAS3,FBXL7,NFIA,RFX4,GPM6A,ADCY2 |
2.909e-04 | -8.14 | nodular | COSMIC cancer mutations | nodular | 1515 | 13 | 16828 | 49 |
NTRK2,CTNND2,ABLIM1,DCLK2,NPAS3,PTPRZ1,ATP13A4,NEBL,ATP1A2,MACF1,GLIS3,SPARCL1,CDH20 |
2.955e-04 | -8.13 | prostate-carcinoma-adenocarcinoma | COSMIC cancer mutations | prostate-carcinoma-adenocarcinoma | 12379 | 46 | 16828 | 49 |
RORA,SOX5,ZBTB20,NTM,SASH1,LRIG1,CSGALNACT1,ATP1A2,PPP2R2B,GPM6A,RFX4,ADCY2,MGAT4C,SORBS1,ATP13A4,MACF1,PRKG1,MAML2,AQP4,QKI,CDH20,GPC5,PCDH9,NPAS3,SLC1A3,LSAMP,TRPS1,ITPR2,BMPR1B,ABLIM1,NRG3,NHSL1,LIFR,NFIA,FBXL7,CTNND2,PTPRZ1,RYR3,NEBL,NTRK2,NKAIN3,PITPNC1,SPARCL1,PARD3B,GLIS3,SLC1A2 |
3.121e-04 | -8.07 | cell-cell junction | cellular component | GO:0005911 | 513 | 7 | 19108 | 49 |
CDH20,SORBS1,CTNNA2,CTNND2,PCDH9,ATP1A2,PARD3B |
3.162e-04 | -8.06 | MIR | pfam domains | PF02815 | 10 | 2 | 17795 | 48 |
ITPR2,RYR3 |
3.170e-04 | -8.06 | MIR_motif | interpro domains | IPR016093 | 10 | 2 | 18521 | 50 |
RYR3,ITPR2 |
3.170e-04 | -8.06 | MIR_dom_sf | interpro domains | IPR036300 | 10 | 2 | 18521 | 50 |
RYR3,ITPR2 |
3.190e-04 | -8.05 | EDTRNSPORT | prints domains | PR00173 | 7 | 2 | 5227 | 21 |
SLC1A3,SLC1A2 |
3.281e-04 | -8.02 | action potential propagation | biological process | GO:0098870 | 10 | 2 | 18204 | 50 |
NTRK2,ATP1A2 |
3.281e-04 | -8.02 | neuronal action potential propagation | biological process | GO:0019227 | 10 | 2 | 18204 | 50 |
NTRK2,ATP1A2 |
3.281e-04 | -8.02 | cellular response to cocaine | biological process | GO:0071314 | 10 | 2 | 18204 | 50 |
SLC1A2,SLC1A3 |
3.423e-04 | -7.98 | animal organ development | biological process | GO:0048513 | 2846 | 18 | 18204 | 50 |
LRIG1,CSGALNACT1,NFIA,PCDH9,ATP1A2,SLC1A2,CTNNA2,RFX4,BMPR1B,DCLK2,PRKG1,RORA,NRG3,NEBL,GPM6A,ABLIM1,NTRK2,SOX5 |
3.508e-04 | -7.96 | IRAG1 (inositol 1,4,5-triphosphate receptor associated 1) | protein interactions | 10335 | 11 | 2 | 19454 | 50 |
PRKG1,ITPR2 |
3.571e-04 | -7.94 | Glutamatergic synapse | KEGG pathways | hsa04724 | 114 | 4 | 7161 | 22 |
SLC1A3,SLC1A2,ADCY2,ITPR2 |
3.571e-04 | -7.94 | Glutamatergic synapse | KEGG pathways | ko04724 | 114 | 4 | 7161 | 22 |
SLC1A3,SLC1A2,ADCY2,ITPR2 |
4.003e-04 | -7.82 | L-aspartate transmembrane transport | biological process | GO:0070778 | 11 | 2 | 18204 | 50 |
SLC1A2,SLC1A3 |
4.003e-04 | -7.82 | L-glutamate import across plasma membrane | biological process | GO:0098712 | 11 | 2 | 18204 | 50 |
SLC1A2,SLC1A3 |
4.146e-04 | -7.79 | regulation of chondrocyte differentiation | biological process | GO:0032330 | 53 | 3 | 18204 | 50 |
TRPS1,BMPR1B,SOX5 |
4.203e-04 | -7.77 | OAS2 (2'-5'-oligoadenylate synthetase 2) | protein interactions | 4939 | 12 | 2 | 19454 | 50 |
PRKG1,SASH1 |
4.282e-04 | -7.76 | haematopoietic_and_lymphoid_tissue | COSMIC cancer mutations | haematopoietic_and_lymphoid_tissue | 14368 | 49 | 16828 | 49 |
AQP4,MAML2,QKI,CDH20,GPC5,SORBS1,PRKG1,ATP13A4,MACF1,DCLK2,ADCY2,GPM6A,PPP2R2B,RFX4,MGAT4C,NTM,SASH1,RORA,SOX5,ZBTB20,LRIG1,ATP1A2,CSGALNACT1,NTRK2,SPARCL1,PARD3B,GLIS3,SLC1A2,NKAIN3,PITPNC1,PTPRZ1,CTNND2,NEBL,RYR3,NHSL1,DTNA,NRG3,ABLIM1,MSI2,FBXL7,NFIA,LIFR,PCDH9,NPAS3,LSAMP,SLC1A3,ITPR2,BMPR1B,TRPS1 |
4.371e-04 | -7.74 | I-set | pfam domains | PF07679 | 132 | 4 | 17795 | 48 |
LSAMP,NTRK2,LRIG1,NTM |
4.404e-04 | -7.73 | Ig_I-set | interpro domains | IPR013098 | 132 | 4 | 18521 | 50 |
NTRK2,LRIG1,LSAMP,NTM |
4.466e-04 | -7.71 | neuron projection | cellular component | GO:0043005 | 1331 | 11 | 19108 | 49 |
GPM6A,SLC1A3,CTNNA2,BMPR1B,DTNA,SLC1A2,ATP1A2,PCDH9,NTRK2,ADCY2,CTNND2 |
4.548e-04 | -7.70 | Ion homeostasis | REACTOME pathways | R-HSA-5578775 | 56 | 3 | 10285 | 28 |
ITPR2,RYR3,ATP1A2 |
5.376e-04 | -7.53 | MIR | prosite domains | PS50919 | 10 | 2 | 12186 | 43 |
RYR3,ITPR2 |
5.442e-04 | -7.52 | NAKATPASE | prints domains | PR00121 | 9 | 2 | 5227 | 21 |
ATP1A2,ATP13A4 |
5.881e-04 | -7.44 | cell junction organization | biological process | GO:0034330 | 532 | 7 | 18204 | 50 |
CTNND2,GPM6A,NRG3,SORBS1,SPARCL1,CDH20,NFIA |
6.145e-04 | -7.39 | L-glutamate transmembrane transporter activity | molecular function | GO:0005313 | 14 | 2 | 18094 | 48 |
SLC1A3,SLC1A2 |
6.542e-04 | -7.33 | upper_aerodigestive_tract | COSMIC cancer mutations | upper_aerodigestive_tract | 13181 | 47 | 16828 | 49 |
NTRK2,PITPNC1,NKAIN3,PARD3B,GLIS3,SLC1A2,CTNND2,PTPRZ1,NEBL,RYR3,NRG3,ABLIM1,NHSL1,DTNA,FBXL7,NFIA,LIFR,MSI2,PCDH9,NPAS3,SLC1A3,LSAMP,TRPS1,ITPR2,BMPR1B,MAML2,QKI,CDH20,GPC5,SORBS1,ATP13A4,MACF1,PRKG1,PPP2R2B,GPM6A,RFX4,DCLK2,ADCY2,MGAT4C,RORA,SOX5,ZBTB20,NTM,SASH1,LRIG1,ATP1A2,CSGALNACT1 |
6.570e-04 | -7.33 | MIR | smart domains | SM00472 | 10 | 2 | 9717 | 38 |
RYR3,ITPR2 |
6.850e-04 | -7.29 | scalp | COSMIC cancer mutations | scalp | 2110 | 15 | 16828 | 49 |
PRKG1,MACF1,TRPS1,ATP1A2,NEBL,ATP13A4,LSAMP,SORBS1,PTPRZ1,NTM,SOX5,RORA,GPC5,NFIA,PPP2R2B |
7.080e-04 | -7.25 | astrocytoma_Grade_I | COSMIC cancer mutations | astrocytoma_Grade_I | 139 | 4 | 16828 | 49 |
QKI,GPC5,PRKG1,NRG3 |
8.086e-04 | -7.12 | human chr3q13.31 | chromosome location | human chr3q13.31 | 22 | 2 | 26134 | 50 |
ZBTB20,LSAMP |
8.795e-04 | -7.04 | retina development in camera-type eye | biological process | GO:0060041 | 156 | 4 | 18204 | 50 |
NFIA,GPM6A,BMPR1B,NTRK2 |
8.890e-04 | -7.03 | cellular response to endogenous stimulus | biological process | GO:0071495 | 1135 | 10 | 18204 | 50 |
BMPR1B,SORBS1,ITPR2,NFIA,RYR3,NTRK2,SLC1A2,SLC1A3,SOX5,ATP1A2 |
8.898e-04 | -7.02 | Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour | COSMIC cancer mutations | Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour | 7434 | 33 | 16828 | 49 |
ABLIM1,NRG3,PPP2R2B,DTNA,ADCY2,DCLK2,LIFR,SOX5,ZBTB20,RORA,SLC1A3,SASH1,NPAS3,CSGALNACT1,TRPS1,ATP1A2,LRIG1,ITPR2,MAML2,NTRK2,NKAIN3,QKI,GLIS3,SPARCL1,PARD3B,CTNND2,SORBS1,PTPRZ1,MACF1,RYR3,NEBL,ATP13A4,PRKG1 |
8.949e-04 | -7.02 | upper_aerodigestive_tract-mouth-carcinoma | COSMIC cancer mutations | upper_aerodigestive_tract-mouth-carcinoma | 6426 | 30 | 16828 | 49 |
PRKG1,MACF1,RYR3,SORBS1,CTNND2,GPC5,SLC1A2,QKI,CDH20,PARD3B,PITPNC1,MAML2,TRPS1,SLC1A3,SASH1,NTM,NPAS3,ZBTB20,SOX5,RORA,MGAT4C,LIFR,FBXL7,NHSL1,ADCY2,ABLIM1,RFX4,NRG3,GPM6A,PPP2R2B |
9.444e-04 | -6.96 | cell adhesion | biological process | GO:0007155 | 942 | 9 | 18204 | 50 |
PARD3B,CDH20,SPARCL1,NTM,SORBS1,CTNNA2,LSAMP,CTNND2,PCDH9 |
1.022e-03 | -6.89 | Htt (huntingtin) | protein interactions | 15194 | 77 | 3 | 19454 | 50 |
GPM6A,NTM,LSAMP |
1.026e-03 | -6.88 | intracellularly gated calcium channel activity | molecular function | GO:0015278 | 18 | 2 | 18094 | 48 |
ITPR2,RYR3 |
1.026e-03 | -6.88 | acidic amino acid transmembrane transporter activity | molecular function | GO:0015172 | 18 | 2 | 18094 | 48 |
SLC1A2,SLC1A3 |
1.027e-03 | -6.88 | large_intestine-adenoma | COSMIC cancer mutations | large_intestine-adenoma | 266 | 5 | 16828 | 49 |
RYR3,SOX5,LIFR,CDH20,SASH1 |
1.043e-03 | -6.87 | synapse | cellular component | GO:0045202 | 1473 | 11 | 19108 | 49 |
ATP1A2,NRG3,NTRK2,CTNND2,DTNA,PTPRZ1,QKI,SLC1A2,GPM6A,SPARCL1,SLC1A3 |
1.057e-03 | -6.85 | metal ion transmembrane transporter activity | molecular function | GO:0046873 | 442 | 6 | 18094 | 48 |
SLC1A3,GPM6A,ATP1A2,RYR3,ITPR2,SLC1A2 |
1.059e-03 | -6.85 | regulation of cartilage development | biological process | GO:0061035 | 73 | 3 | 18204 | 50 |
BMPR1B,SOX5,TRPS1 |
1.060e-03 | -6.85 | Cation_ATPase_N | pfam domains | PF00690 | 18 | 2 | 17795 | 48 |
ATP13A4,ATP1A2 |
1.063e-03 | -6.85 | ATPase_P-typ_cation-transptr_N | interpro domains | IPR004014 | 18 | 2 | 18521 | 50 |
ATP1A2,ATP13A4 |
1.071e-03 | -6.84 | astrocyte projection | cellular component | GO:0097449 | 19 | 2 | 19108 | 49 |
SLC1A2,AQP4 |
1.100e-03 | -6.81 | positive regulation of circadian rhythm | biological process | GO:0042753 | 18 | 2 | 18204 | 50 |
RORA,PRKG1 |
1.158e-03 | -6.76 | superficial_spreading | COSMIC cancer mutations | superficial_spreading | 1110 | 10 | 16828 | 49 |
NTM,ADCY2,SORBS1,PPP2R2B,CTNND2,MGAT4C,PRKG1,ATP13A4,LIFR,MACF1 |
1.165e-03 | -6.76 | lung-carcinoma-squamous_cell_carcinoma | COSMIC cancer mutations | lung-carcinoma-squamous_cell_carcinoma | 14664 | 49 | 16828 | 49 |
NRG3,ABLIM1,NHSL1,DTNA,FBXL7,LIFR,NFIA,MSI2,NPAS3,PCDH9,SLC1A3,LSAMP,TRPS1,ITPR2,BMPR1B,NTRK2,NKAIN3,PITPNC1,PARD3B,SPARCL1,GLIS3,SLC1A2,CTNND2,PTPRZ1,NEBL,RYR3,GPM6A,PPP2R2B,RFX4,DCLK2,ADCY2,MGAT4C,RORA,SOX5,ZBTB20,NTM,SASH1,LRIG1,ATP1A2,CSGALNACT1,AQP4,MAML2,CDH20,QKI,GPC5,SORBS1,ATP13A4,MACF1,PRKG1 |
1.215e-03 | -6.71 | central_nervous_system-brain-primitive_neuroectodermal_tumour-medulloblastoma-large_cell | COSMIC cancer mutations | central_nervous_system-brain-primitive_neuroectodermal_tumour-medulloblastoma-large_cell | 1117 | 10 | 16828 | 49 |
GPC5,SLC1A2,PRKG1,QKI,CDH20,ATP13A4,RYR3,ADCY2,SOX5,NRG3 |
1.226e-03 | -6.70 | GSC (goosecoid homeobox) | protein interactions | 145258 | 82 | 3 | 19454 | 50 |
SOX5,TRPS1,NFIA |
1.227e-03 | -6.70 | cartilage condensation | biological process | GO:0001502 | 19 | 2 | 18204 | 50 |
SOX5,BMPR1B |
1.257e-03 | -6.68 | Bile secretion | KEGG pathways | hsa04976 | 71 | 3 | 7161 | 22 |
AQP4,ADCY2,ATP1A2 |
1.257e-03 | -6.68 | Bile secretion | KEGG pathways | ko04976 | 71 | 3 | 7161 | 22 |
ATP1A2,AQP4,ADCY2 |
1.277e-03 | -6.66 | monoatomic cation transmembrane transporter activity | molecular function | GO:0008324 | 630 | 7 | 18094 | 48 |
SLC1A3,RYR3,SLC1A2,GPM6A,ATP1A2,ATP13A4,ITPR2 |
1.283e-03 | -6.66 | dicarboxylic acid transport | biological process | GO:0006835 | 78 | 3 | 18204 | 50 |
NTRK2,SLC1A3,SLC1A2 |
1.289e-03 | -6.65 | cell morphogenesis involved in neuron differentiation | biological process | GO:0048667 | 443 | 6 | 18204 | 50 |
PRKG1,BMPR1B,PTPRZ1,CTNNA2,SLC1A3,CTNND2 |
1.290e-03 | -6.65 | cartilage development | biological process | GO:0051216 | 173 | 4 | 18204 | 50 |
NFIA,CSGALNACT1,SOX5,BMPR1B |
1.318e-03 | -6.63 | TENM1 (teneurin transmembrane protein 1) | protein interactions | 10178 | 21 | 2 | 19454 | 50 |
SORBS1,MACF1 |
1.321e-03 | -6.63 | stomach-adenocarcinoma | COSMIC cancer mutations | stomach-adenocarcinoma | 4101 | 22 | 16828 | 49 |
ITPR2,ATP1A2,TRPS1,CSGALNACT1,LRIG1,SASH1,PCDH9,RORA,MGAT4C,RFX4,NRG3,ABLIM1,PPP2R2B,MACF1,NEBL,ATP13A4,CTNND2,GPC5,SLC1A2,PARD3B,QKI,CDH20 |
1.332e-03 | -6.62 | skin-mucosal-malignant_melanoma | COSMIC cancer mutations | skin-mucosal-malignant_melanoma | 2009 | 14 | 16828 | 49 |
CTNND2,RORA,SORBS1,PCDH9,ATP1A2,NEBL,ATP13A4,BMPR1B,ABLIM1,NRG3,PPP2R2B,LIFR,SPARCL1,MGAT4C |
1.332e-03 | -6.62 | mucosal | COSMIC cancer mutations | mucosal | 2009 | 14 | 16828 | 49 |
RORA,CTNND2,PCDH9,SORBS1,NEBL,ATP13A4,ATP1A2,BMPR1B,PPP2R2B,NRG3,ABLIM1,LIFR,MGAT4C,SPARCL1 |
1.357e-03 | -6.60 | plasma membrane bounded cell projection | cellular component | GO:0120025 | 2285 | 14 | 19108 | 49 |
PCDH9,NTRK2,MACF1,CTNND2,AQP4,ATP1A2,CTNNA2,ADCY2,DTNA,SLC1A2,BMPR1B,SLC1A3,GPM6A,ABLIM1 |
1.361e-03 | -6.60 | aspartate transmembrane transport | biological process | GO:0015810 | 20 | 2 | 18204 | 50 |
SLC1A2,SLC1A3 |
1.361e-03 | -6.60 | positive regulation of chondrocyte differentiation | biological process | GO:0032332 | 20 | 2 | 18204 | 50 |
BMPR1B,SOX5 |
1.374e-03 | -6.59 | cGMP-PKG signaling pathway | KEGG pathways | ko04022 | 163 | 4 | 7161 | 22 |
PRKG1,ATP1A2,ITPR2,ADCY2 |
1.374e-03 | -6.59 | cGMP-PKG signaling pathway | KEGG pathways | hsa04022 | 163 | 4 | 7161 | 22 |
ADCY2,ITPR2,PRKG1,ATP1A2 |
1.375e-03 | -6.59 | central nervous system neuron differentiation | biological process | GO:0021953 | 176 | 4 | 18204 | 50 |
RORA,BMPR1B,NTRK2,DCLK2 |
1.397e-03 | -6.57 | stress fiber | cellular component | GO:0001725 | 86 | 3 | 19108 | 49 |
SORBS1,ABLIM1,NEBL |
1.397e-03 | -6.57 | contractile actin filament bundle | cellular component | GO:0097517 | 86 | 3 | 19108 | 49 |
NEBL,ABLIM1,SORBS1 |
1.417e-03 | -6.56 | Thyroid hormone synthesis | KEGG pathways | hsa04918 | 74 | 3 | 7161 | 22 |
ATP1A2,ADCY2,ITPR2 |
1.417e-03 | -6.56 | Thyroid hormone synthesis | KEGG pathways | ko04918 | 74 | 3 | 7161 | 22 |
ATP1A2,ADCY2,ITPR2 |
1.439e-03 | -6.54 | thyroid-carcinoma | COSMIC cancer mutations | thyroid-carcinoma | 4126 | 22 | 16828 | 49 |
PTPRZ1,PCDH9,LSAMP,SASH1,CTNND2,SOX5,ITPR2,PRKG1,RYR3,ATP13A4,LRIG1,TRPS1,MACF1,ATP1A2,ADCY2,DTNA,AQP4,GLIS3,SPARCL1,GPC5,NFIA,LIFR |
1.473e-03 | -6.52 | Gastric acid secretion | KEGG pathways | ko04971 | 75 | 3 | 7161 | 22 |
ADCY2,ITPR2,ATP1A2 |
1.473e-03 | -6.52 | Gastric acid secretion | KEGG pathways | hsa04971 | 75 | 3 | 7161 | 22 |
ATP1A2,ADCY2,ITPR2 |
1.502e-03 | -6.50 | cell aggregation | biological process | GO:0098743 | 21 | 2 | 18204 | 50 |
SOX5,BMPR1B |
1.548e-03 | -6.47 | SFN (stratifin) | protein interactions | 2810 | 671 | 7 | 19454 | 50 |
MACF1,NFIA,PARD3B,PPP2R2B,SASH1,ABLIM1,SORBS1 |
1.563e-03 | -6.46 | haematopoietic_neoplasm | COSMIC cancer mutations | haematopoietic_neoplasm | 11082 | 42 | 16828 | 49 |
MSI2,FBXL7,LIFR,NFIA,DTNA,DCLK2,ADCY2,NHSL1,NRG3,RFX4,ABLIM1,PPP2R2B,BMPR1B,ITPR2,ATP1A2,CSGALNACT1,LRIG1,SASH1,LSAMP,SLC1A3,PCDH9,NTM,NPAS3,SOX5,RORA,GPC5,SLC1A2,GLIS3,PARD3B,SPARCL1,CDH20,QKI,NKAIN3,MAML2,NTRK2,PRKG1,MACF1,ATP13A4,NEBL,RYR3,PTPRZ1,CTNND2 |
1.582e-03 | -6.45 | Rbm38 (RNA binding motif protein 38) | protein interactions | 56190 | 23 | 2 | 19454 | 50 |
MSI2,QKI |
1.587e-03 | -6.45 | regulation of carbohydrate metabolic process | biological process | GO:0006109 | 183 | 4 | 18204 | 50 |
SORBS1,ZBTB20,RORA,PRKG1 |
1.649e-03 | -6.41 | negative regulation of muscle contraction | biological process | GO:0045932 | 22 | 2 | 18204 | 50 |
ATP1A2,PRKG1 |
1.649e-03 | -6.41 | intracellular sodium ion homeostasis | biological process | GO:0006883 | 22 | 2 | 18204 | 50 |
SLC1A3,ATP1A2 |
1.683e-03 | -6.39 | amino acid:sodium symporter activity | molecular function | GO:0005283 | 23 | 2 | 18094 | 48 |
SLC1A2,SLC1A3 |
1.695e-03 | -6.38 | actomyosin | cellular component | GO:0042641 | 92 | 3 | 19108 | 49 |
SORBS1,NEBL,ABLIM1 |
1.700e-03 | -6.38 | vascular transport | biological process | GO:0010232 | 86 | 3 | 18204 | 50 |
ATP1A2,SLC1A2,SLC1A3 |
1.700e-03 | -6.38 | transport across blood-brain barrier | biological process | GO:0150104 | 86 | 3 | 18204 | 50 |
SLC1A2,SLC1A3,ATP1A2 |
1.726e-03 | -6.36 | Cation_ATPase_N | smart domains | SM00831 | 16 | 2 | 9717 | 38 |
ATP13A4,ATP1A2 |
1.748e-03 | -6.35 | parathyroid-carcinoma | COSMIC cancer mutations | parathyroid-carcinoma | 300 | 5 | 16828 | 49 |
GPC5,PRKG1,RYR3,MACF1,TRPS1 |
1.781e-03 | -6.33 | ovary-carcinoma-serous_carcinoma | COSMIC cancer mutations | ovary-carcinoma-serous_carcinoma | 10710 | 41 | 16828 | 49 |
MGAT4C,MSI2,LIFR,FBXL7,ADCY2,NHSL1,DCLK2,DTNA,PPP2R2B,NRG3,ITPR2,BMPR1B,LRIG1,CSGALNACT1,TRPS1,ATP1A2,NTM,NPAS3,PCDH9,SLC1A3,LSAMP,SASH1,RORA,SOX5,ZBTB20,CDH20,QKI,PARD3B,GLIS3,SLC1A2,GPC5,NTRK2,MAML2,PRKG1,RYR3,NEBL,ATP13A4,MACF1,PTPRZ1,SORBS1,CTNND2 |
1.803e-03 | -6.32 | relaxation of muscle | biological process | GO:0090075 | 23 | 2 | 18204 | 50 |
ATP1A2,PRKG1 |
1.815e-03 | -6.31 | Transmembrane transport of small molecules | REACTOME pathways | R-HSA-382551 | 677 | 7 | 10285 | 28 |
ATP13A4,ADCY2,RYR3,SLC1A2,SLC1A3,ATP1A2,AQP4 |
1.832e-03 | -6.30 | P-type ion transporter activity | molecular function | GO:0015662 | 24 | 2 | 18094 | 48 |
ATP1A2,ATP13A4 |
1.832e-03 | -6.30 | P-type transmembrane transporter activity | molecular function | GO:0140358 | 24 | 2 | 18094 | 48 |
ATP1A2,ATP13A4 |
1.901e-03 | -6.27 | Glutamate Neurotransmitter Release Cycle | REACTOME pathways | R-HSA-210500 | 24 | 2 | 10285 | 28 |
SLC1A2,SLC1A3 |
1.913e-03 | -6.26 | human chr12q21.31-q21.32 | chromosome location | human chr12q21.31-q21.32 | 1 | 1 | 26134 | 50 |
MGAT4C |
1.913e-03 | -6.26 | human chr10q11.23-q21.1 | chromosome location | human chr10q11.23-q21.1 | 1 | 1 | 26134 | 50 |
PRKG1 |
1.913e-03 | -6.26 | human chr6q24.3-q25.1 | chromosome location | human chr6q24.3-q25.1 | 1 | 1 | 26134 | 50 |
SASH1 |
1.913e-03 | -6.26 | human chr4q31.23-q31.3 | chromosome location | human chr4q31.23-q31.3 | 1 | 1 | 26134 | 50 |
DCLK2 |
1.913e-03 | -6.26 | human chr15q13.3-q14 | chromosome location | human chr15q13.3-q14 | 1 | 1 | 26134 | 50 |
RYR3 |
1.915e-03 | -6.26 | actin filament bundle | cellular component | GO:0032432 | 96 | 3 | 19108 | 49 |
SORBS1,ABLIM1,NEBL |
1.920e-03 | -6.26 | urinary_tract-bladder-carcinoma-transitional_cell_carcinoma | COSMIC cancer mutations | urinary_tract-bladder-carcinoma-transitional_cell_carcinoma | 6040 | 28 | 16828 | 49 |
CDH20,PARD3B,SPARCL1,GLIS3,GPC5,NTRK2,NEBL,ATP13A4,MACF1,PRKG1,PTPRZ1,SORBS1,NFIA,MGAT4C,GPM6A,ABLIM1,RFX4,NRG3,ADCY2,DTNA,LRIG1,TRPS1,ATP1A2,ITPR2,ZBTB20,PCDH9,SLC1A3,SASH1 |
1.931e-03 | -6.25 | transitional_cell_carcinoma | COSMIC cancer mutations | transitional_cell_carcinoma | 6042 | 28 | 16828 | 49 |
MACF1,NEBL,ATP13A4,PRKG1,SORBS1,PTPRZ1,GPC5,CDH20,GLIS3,SPARCL1,PARD3B,NTRK2,TRPS1,ATP1A2,LRIG1,ITPR2,ZBTB20,SLC1A3,SASH1,PCDH9,NFIA,MGAT4C,ABLIM1,RFX4,NRG3,GPM6A,DTNA,ADCY2 |
1.957e-03 | -6.24 | bone-femur-other-chondroblastoma | COSMIC cancer mutations | bone-femur-other-chondroblastoma | 183 | 4 | 16828 | 49 |
NRG3,RYR3,GPC5,PCDH9 |
2.062e-03 | -6.18 | neuron projection morphogenesis | biological process | GO:0048812 | 486 | 6 | 18204 | 50 |
PRKG1,BMPR1B,CTNNA2,PTPRZ1,CTNND2,GPM6A |
2.118e-03 | -6.16 | Muscle contraction | REACTOME pathways | R-HSA-397014 | 204 | 4 | 10285 | 28 |
ATP1A2,SORBS1,RYR3,ITPR2 |
2.130e-03 | -6.15 | L-glutamate transmembrane transport | biological process | GO:0015813 | 25 | 2 | 18204 | 50 |
SLC1A2,SLC1A3 |
2.146e-03 | -6.14 | synapse organization | biological process | GO:0050808 | 333 | 5 | 18204 | 50 |
NRG3,SPARCL1,GPM6A,CTNND2,NFIA |
2.152e-03 | -6.14 | extrinsic component of plasma membrane | cellular component | GO:0019897 | 100 | 3 | 19108 | 49 |
CTNNA2,CDH20,DTNA |
2.161e-03 | -6.14 | cell projection | cellular component | GO:0042995 | 2398 | 14 | 19108 | 49 |
AQP4,ATP1A2,PCDH9,CTNND2,MACF1,NTRK2,CTNNA2,ADCY2,BMPR1B,DTNA,SLC1A2,GPM6A,ABLIM1,SLC1A3 |
2.170e-03 | -6.13 | cell development | biological process | GO:0048468 | 2236 | 14 | 18204 | 50 |
CTNND2,CTNNA2,MSI2,QKI,GPM6A,SLC1A3,NTRK2,NEBL,PTPRZ1,DCLK2,BMPR1B,NTM,RORA,PRKG1 |
2.171e-03 | -6.13 | plasma membrane bounded cell projection morphogenesis | biological process | GO:0120039 | 491 | 6 | 18204 | 50 |
BMPR1B,PRKG1,CTNND2,GPM6A,PTPRZ1,CTNNA2 |
2.181e-03 | -6.13 | MBNL2 (muscleblind like splicing regulator 2) | protein interactions | 10150 | 27 | 2 | 19454 | 50 |
QKI,MSI2 |
2.181e-03 | -6.13 | KCNJ12 (potassium inwardly rectifying channel subfamily J member 12) | protein interactions | 3768 | 27 | 2 | 19454 | 50 |
DTNA,ABLIM1 |
2.181e-03 | -6.13 | HPCAL4 (hippocalcin like 4) | protein interactions | 51440 | 27 | 2 | 19454 | 50 |
GPM6A,AQP4 |
2.284e-03 | -6.08 | cell projection morphogenesis | biological process | GO:0048858 | 496 | 6 | 18204 | 50 |
PRKG1,CTNNA2,PTPRZ1,CTNND2,BMPR1B,GPM6A |
2.304e-03 | -6.07 | C4-dicarboxylate transport | biological process | GO:0015740 | 26 | 2 | 18204 | 50 |
SLC1A2,SLC1A3 |
2.332e-03 | -6.06 | Gap junction | KEGG pathways | ko04540 | 88 | 3 | 7161 | 22 |
PRKG1,ITPR2,ADCY2 |
2.332e-03 | -6.06 | Gap junction | KEGG pathways | hsa04540 | 88 | 3 | 7161 | 22 |
ITPR2,ADCY2,PRKG1 |
2.341e-03 | -6.06 | actin filament binding | molecular function | GO:0051015 | 211 | 4 | 18094 | 48 |
MACF1,ABLIM1,NEBL,CTNNA2 |
2.362e-03 | -6.05 | skin-head_neck-carcinoma-squamous_cell_carcinoma | COSMIC cancer mutations | skin-head_neck-carcinoma-squamous_cell_carcinoma | 14191 | 48 | 16828 | 49 |
RFX4,PPP2R2B,GPM6A,DCLK2,ADCY2,MGAT4C,ZBTB20,SOX5,RORA,SASH1,NTM,CSGALNACT1,ATP1A2,LRIG1,MAML2,AQP4,GPC5,QKI,CDH20,SORBS1,MACF1,ATP13A4,PRKG1,ABLIM1,NRG3,DTNA,NHSL1,NFIA,LIFR,FBXL7,SLC1A3,LSAMP,NPAS3,PCDH9,TRPS1,BMPR1B,ITPR2,NTRK2,NKAIN3,PITPNC1,SLC1A2,GLIS3,SPARCL1,PARD3B,CTNND2,PTPRZ1,RYR3,NEBL |
2.412e-03 | -6.03 | haematopoietic_and_lymphoid_tissue-spleen-lymphoid_neoplasm-marginal_zone_lymphoma | COSMIC cancer mutations | haematopoietic_and_lymphoid_tissue-spleen-lymphoid_neoplasm-marginal_zone_lymphoma | 323 | 5 | 16828 | 49 |
ADCY2,PARD3B,NTM,PTPRZ1,SORBS1 |
2.424e-03 | -6.02 | HUNK (hormonally up-regulated Neu-associated kinase) | protein interactions | 30811 | 104 | 3 | 19454 | 50 |
SORBS1,SPARCL1,ABLIM1 |
2.476e-03 | -6.00 | parathyroid | COSMIC cancer mutations | parathyroid | 476 | 6 | 16828 | 49 |
GPM6A,TRPS1,MACF1,RYR3,GPC5,PRKG1 |
2.478e-03 | -6.00 | Calcium-transporting ATPase, transmembrane domain | gene3d domains | 1.20.1110.10 | 25 | 2 | 14470 | 43 |
ATP13A4,ATP1A2 |
2.550e-03 | -5.97 | lung-carcinoma-non_small_cell_carcinoma | COSMIC cancer mutations | lung-carcinoma-non_small_cell_carcinoma | 5198 | 25 | 16828 | 49 |
PTPRZ1,CTNND2,PRKG1,ATP13A4,NTRK2,MAML2,SPARCL1,QKI,PITPNC1,NPAS3,SLC1A3,LSAMP,RORA,SOX5,ITPR2,BMPR1B,LRIG1,TRPS1,ADCY2,DCLK2,PPP2R2B,ABLIM1,MSI2,FBXL7,LIFR |
2.550e-03 | -5.97 | non_small_cell_carcinoma | COSMIC cancer mutations | non_small_cell_carcinoma | 5198 | 25 | 16828 | 49 |
MSI2,LIFR,FBXL7,DCLK2,ADCY2,ABLIM1,PPP2R2B,BMPR1B,ITPR2,TRPS1,LRIG1,SLC1A3,LSAMP,NPAS3,SOX5,RORA,QKI,SPARCL1,PITPNC1,MAML2,NTRK2,PRKG1,ATP13A4,PTPRZ1,CTNND2 |
2.570e-03 | -5.96 | Lztr1 (leucine-zipper-like transcriptional regulator, 1) | protein interactions | 66863 | 1 | 1 | 19454 | 50 |
BMPR1B |
2.570e-03 | -5.96 | 1700006A11Rik (RIKEN cDNA 1700006A11 gene) | protein interactions | 71824 | 1 | 1 | 19454 | 50 |
BMPR1B |
2.570e-03 | -5.96 | Agtrap (angiotensin II, type I receptor-associated protein) | protein interactions | 11610 | 1 | 1 | 19454 | 50 |
PITPNC1 |
2.570e-03 | -5.96 | Hipk3 (homeodomain interacting protein kinase 3) | protein interactions | 15259 | 1 | 1 | 19454 | 50 |
GLIS3 |
2.570e-03 | -5.96 | Dcaf7 (DDB1 and CUL4 associated factor 7) | protein interactions | 71833 | 1 | 1 | 19454 | 50 |
BMPR1B |
2.570e-03 | -5.96 | Bdnf (brain derived neurotrophic factor) | protein interactions | 12064 | 1 | 1 | 19454 | 50 |
NTRK2 |
2.570e-03 | -5.96 | Isl1 (ISL1 transcription factor, LIM/homeodomain) | protein interactions | 16392 | 1 | 1 | 19454 | 50 |
GLIS3 |
2.570e-03 | -5.96 | Dynlt1 (dynein light chain Tctex-type 1) | protein interactions | 83462 | 1 | 1 | 19454 | 50 |
NTRK2 |
2.602e-03 | -5.95 | inorganic molecular entity transmembrane transporter activity | molecular function | GO:0015318 | 714 | 7 | 18094 | 48 |
SLC1A3,SLC1A2,RYR3,ATP1A2,GPM6A,AQP4,ITPR2 |
2.614e-03 | -5.95 | response to alkaloid | biological process | GO:0043279 | 100 | 3 | 18204 | 50 |
SLC1A2,SLC1A3,RYR3 |
2.645e-03 | -5.94 | tibia | COSMIC cancer mutations | tibia | 836 | 8 | 16828 | 49 |
LSAMP,GPM6A,CTNND2,ABLIM1,QKI,PRKG1,MACF1,NKAIN3 |
2.653e-03 | -5.93 | internal N(7)-methylguanine-containing RNA reader activity | molecular function | GO:0160089 | 1 | 1 | 18094 | 48 |
QKI |
2.653e-03 | -5.93 | brain-derived neurotrophic factor receptor activity | molecular function | GO:0060175 | 1 | 1 | 18094 | 48 |
NTRK2 |
2.653e-03 | -5.93 | peptidoglycan glycosyltransferase activity | molecular function | GO:0008955 | 1 | 1 | 18094 | 48 |
CSGALNACT1 |
2.670e-03 | -5.93 | positive regulation of oligodendrocyte differentiation | biological process | GO:0048714 | 28 | 2 | 18204 | 50 |
PTPRZ1,QKI |
2.673e-03 | -5.92 | ligand-gated calcium channel activity | molecular function | GO:0099604 | 29 | 2 | 18094 | 48 |
RYR3,ITPR2 |
2.673e-03 | -5.92 | amino acid:monoatomic cation symporter activity | molecular function | GO:0005416 | 29 | 2 | 18094 | 48 |
SLC1A2,SLC1A3 |
2.681e-03 | -5.92 | marginal_zone_lymphoma | COSMIC cancer mutations | marginal_zone_lymphoma | 331 | 5 | 16828 | 49 |
NTM,PTPRZ1,ADCY2,PARD3B,SORBS1 |
2.697e-03 | -5.92 | MAML2_TAD | pfam domains | PF20804 | 1 | 1 | 17795 | 48 |
MAML2 |
2.697e-03 | -5.92 | LIFR_N | pfam domains | PF18207 | 1 | 1 | 17795 | 48 |
LIFR |
2.697e-03 | -5.92 | PKcGMP_CC | pfam domains | PF16808 | 1 | 1 | 17795 | 48 |
PRKG1 |
2.697e-03 | -5.92 | Quaking_NLS | pfam domains | PF16551 | 1 | 1 | 17795 | 48 |
QKI |
2.697e-03 | -5.92 | STAR_dimer | pfam domains | PF16544 | 1 | 1 | 17795 | 48 |
QKI |
2.700e-03 | -5.91 | PKcGMP_CC | interpro domains | IPR031831 | 1 | 1 | 18521 | 50 |
PRKG1 |
2.700e-03 | -5.91 | Quaking_NLS | interpro domains | IPR032367 | 1 | 1 | 18521 | 50 |
QKI |
2.700e-03 | -5.91 | SASH1_SAM_repeat2 | interpro domains | IPR037630 | 1 | 1 | 18521 | 50 |
SASH1 |
2.700e-03 | -5.91 | SORBS1_SH3_2 | interpro domains | IPR035611 | 1 | 1 | 18521 | 50 |
SORBS1 |
2.700e-03 | -5.91 | STAR_dimer | interpro domains | IPR032377 | 1 | 1 | 18521 | 50 |
QKI |
2.700e-03 | -5.91 | SPARC-like_p1 | interpro domains | IPR016359 | 1 | 1 | 18521 | 50 |
SPARCL1 |
2.700e-03 | -5.91 | SORBS1_SH3 | interpro domains | IPR035606 | 1 | 1 | 18521 | 50 |
SORBS1 |
2.700e-03 | -5.91 | TRPS1 | interpro domains | IPR028440 | 1 | 1 | 18521 | 50 |
TRPS1 |
2.700e-03 | -5.91 | SASH1_SAM_repeat1 | interpro domains | IPR037627 | 1 | 1 | 18521 | 50 |
SASH1 |
2.700e-03 | -5.91 | MAML2_TAD | interpro domains | IPR048452 | 1 | 1 | 18521 | 50 |
MAML2 |
2.700e-03 | -5.91 | LIFR_N | interpro domains | IPR040901 | 1 | 1 | 18521 | 50 |
LIFR |
2.700e-03 | -5.91 | SASH1_SH3 | interpro domains | IPR035720 | 1 | 1 | 18521 | 50 |
SASH1 |
2.700e-03 | -5.91 | NTRK2 | interpro domains | IPR020455 | 1 | 1 | 18521 | 50 |
NTRK2 |
2.700e-03 | -5.91 | Nebulette_SH3 | interpro domains | IPR035631 | 1 | 1 | 18521 | 50 |
NEBL |
2.700e-03 | -5.91 | SORBS1_SH3_1 | interpro domains | IPR035610 | 1 | 1 | 18521 | 50 |
SORBS1 |
2.709e-03 | -5.91 | large_intestine-caecum-carcinoma-adenocarcinoma | COSMIC cancer mutations | large_intestine-caecum-carcinoma-adenocarcinoma | 14236 | 48 | 16828 | 49 |
SORBS1,PRKG1,MACF1,ATP13A4,AQP4,MAML2,GPC5,CDH20,QKI,SASH1,NTM,ZBTB20,SOX5,RORA,ATP1A2,CSGALNACT1,LRIG1,ADCY2,DCLK2,RFX4,GPM6A,PPP2R2B,MGAT4C,PTPRZ1,CTNND2,NEBL,RYR3,NTRK2,SLC1A2,PARD3B,GLIS3,SPARCL1,PITPNC1,NKAIN3,LSAMP,SLC1A3,PCDH9,NPAS3,BMPR1B,ITPR2,TRPS1,DTNA,NHSL1,NRG3,ABLIM1,FBXL7,LIFR,NFIA |
2.718e-03 | -5.91 | NR3C1 (nuclear receptor subfamily 3 group C member 1) | protein interactions | 2908 | 950 | 8 | 19454 | 50 |
ADCY2,PPP2R2B,ATP13A4,ZBTB20,SLC1A3,TRPS1,NFIA,CTNND2 |
2.747e-03 | -5.90 | negative regulation of calcium:sodium antiporter activity | biological process | GO:1903280 | 1 | 1 | 18204 | 50 |
ATP1A2 |
2.747e-03 | -5.90 | directional guidance of interneurons involved in migration from the subpallium to the cortex | biological process | GO:0021840 | 1 | 1 | 18204 | 50 |
NRG3 |
2.747e-03 | -5.90 | trans-synaptic signaling by neuropeptide | biological process | GO:0099540 | 1 | 1 | 18204 | 50 |
NTRK2 |
2.747e-03 | -5.90 | olfactory cortex development | biological process | GO:0021989 | 1 | 1 | 18204 | 50 |
ATP1A2 |
2.747e-03 | -5.90 | chemorepulsion involved in interneuron migration from the subpallium to the cortex | biological process | GO:0021842 | 1 | 1 | 18204 | 50 |
NRG3 |
2.747e-03 | -5.90 | trans-synaptic signaling by neuropeptide, modulating synaptic transmission | biological process | GO:0099551 | 1 | 1 | 18204 | 50 |
NTRK2 |
2.809e-03 | -5.87 | caecum | COSMIC cancer mutations | caecum | 14248 | 48 | 16828 | 49 |
NTM,SASH1,RORA,ZBTB20,SOX5,LRIG1,CSGALNACT1,ATP1A2,DCLK2,ADCY2,PPP2R2B,GPM6A,RFX4,MGAT4C,SORBS1,PRKG1,ATP13A4,MACF1,MAML2,AQP4,QKI,CDH20,GPC5,PCDH9,NPAS3,LSAMP,SLC1A3,ITPR2,BMPR1B,TRPS1,NHSL1,DTNA,ABLIM1,NRG3,LIFR,NFIA,FBXL7,PTPRZ1,CTNND2,RYR3,NEBL,NTRK2,PARD3B,GLIS3,SPARCL1,SLC1A2,PITPNC1,NKAIN3 |
2.857e-03 | -5.86 | cell body | cellular component | GO:0044297 | 556 | 6 | 19108 | 49 |
SLC1A3,GPM6A,SLC1A2,CTNND2,BMPR1B,ATP1A2 |
2.857e-03 | -5.86 | catenin complex | cellular component | GO:0016342 | 31 | 2 | 19108 | 49 |
CDH20,CTNNA2 |
2.901e-03 | -5.84 | Pancreatic secretion | KEGG pathways | hsa04972 | 95 | 3 | 7161 | 22 |
ITPR2,ADCY2,ATP1A2 |
2.901e-03 | -5.84 | Pancreatic secretion | KEGG pathways | ko04972 | 95 | 3 | 7161 | 22 |
ITPR2,ADCY2,ATP1A2 |
2.972e-03 | -5.82 | - | gene3d domains | 1.20.5.4010 | 1 | 1 | 14470 | 43 |
QKI |
2.989e-03 | -5.81 | Circadian entrainment | KEGG pathways | hsa04713 | 96 | 3 | 7161 | 22 |
PRKG1,RYR3,ADCY2 |
2.989e-03 | -5.81 | Circadian entrainment | KEGG pathways | ko04713 | 96 | 3 | 7161 | 22 |
RYR3,ADCY2,PRKG1 |
2.991e-03 | -5.81 | TBR1 (T-box brain transcription factor 1) | protein interactions | 10716 | 112 | 3 | 19454 | 50 |
SOX5,NFIA,TRPS1 |
2.993e-03 | -5.81 | YWHAB (tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein beta) | protein interactions | 7529 | 965 | 8 | 19454 | 50 |
PARD3B,PITPNC1,NHSL1,SASH1,SORBS1,ABLIM1,MACF1,DCLK2 |
3.002e-03 | -5.81 | neural precursor cell proliferation | biological process | GO:0061351 | 105 | 3 | 18204 | 50 |
SOX5,NFIA,RORA |
3.005e-03 | -5.81 | SH3_domain | interpro domains | IPR001452 | 222 | 4 | 18521 | 50 |
NEBL,SORBS1,MACF1,SASH1 |
3.044e-03 | -5.79 | glial cell differentiation | biological process | GO:0010001 | 219 | 4 | 18204 | 50 |
QKI,NTRK2,NFIA,PTPRZ1 |
3.051e-03 | -5.79 | intracellularly ligand-gated monoatomic ion channel activity | molecular function | GO:0005217 | 31 | 2 | 18094 | 48 |
ITPR2,RYR3 |
3.055e-03 | -5.79 | CDH1 (cadherin 1) | protein interactions | 999 | 757 | 7 | 19454 | 50 |
CTNND2,CTNNA2,MACF1,ABLIM1,SORBS1,NEBL,NHSL1 |
3.057e-03 | -5.79 | DSG3 (desmoglein 3) | protein interactions | 1830 | 32 | 2 | 19454 | 50 |
PPP2R2B,CSGALNACT1 |
3.062e-03 | -5.79 | L-glutamate import | biological process | GO:0051938 | 30 | 2 | 18204 | 50 |
SLC1A3,SLC1A2 |
3.093e-03 | -5.78 | MARK3 (microtubule affinity regulating kinase 3) | protein interactions | 4140 | 235 | 4 | 19454 | 50 |
PPP2R2B,MACF1,DTNA,NTRK2 |
3.144e-03 | -5.76 | ORF3b (ORF3b protein) | protein interactions | 1489670 | 114 | 3 | 19454 | 50 |
MACF1,ZBTB20,PCDH9 |
3.152e-03 | -5.76 | E1-E2_ATPase | pfam domains | PF00122 | 31 | 2 | 17795 | 48 |
ATP13A4,ATP1A2 |
3.289e-03 | -5.72 | diffuse_adenocarcinoma | COSMIC cancer mutations | diffuse_adenocarcinoma | 4383 | 22 | 16828 | 49 |
PRKG1,ATP1A2,TRPS1,MACF1,RYR3,SASH1,SLC1A3,PCDH9,PTPRZ1,CTNND2,SOX5,GLIS3,MGAT4C,QKI,LIFR,DTNA,ADCY2,NHSL1,NRG3,RFX4,ABLIM1,GPM6A |
3.289e-03 | -5.72 | stomach-carcinoma-diffuse_adenocarcinoma | COSMIC cancer mutations | stomach-carcinoma-diffuse_adenocarcinoma | 4383 | 22 | 16828 | 49 |
SLC1A3,SASH1,PCDH9,SOX5,TRPS1,ATP1A2,DTNA,NHSL1,ADCY2,ABLIM1,NRG3,RFX4,GPM6A,MGAT4C,LIFR,PTPRZ1,CTNND2,PRKG1,MACF1,RYR3,QKI,GLIS3 |
3.302e-03 | -5.71 | SKIL (SKI like proto-oncogene) | protein interactions | 6498 | 116 | 3 | 19454 | 50 |
SASH1,MACF1,SPARCL1 |
3.349e-03 | -5.70 | oesophagus-middle_third-carcinoma-squamous_cell_carcinoma | COSMIC cancer mutations | oesophagus-middle_third-carcinoma-squamous_cell_carcinoma | 3531 | 19 | 16828 | 49 |
CTNND2,SOX5,ZBTB20,PCDH9,PTPRZ1,SASH1,NEBL,LRIG1,RYR3,ATP1A2,MACF1,GPM6A,NRG3,MAML2,ABLIM1,NHSL1,ADCY2,SPARCL1,GPC5 |
3.352e-03 | -5.70 | skin-ear-carcinoma-squamous_cell_carcinoma | COSMIC cancer mutations | skin-ear-carcinoma-squamous_cell_carcinoma | 506 | 6 | 16828 | 49 |
LIFR,PRKG1,SPARCL1,MGAT4C,ZBTB20,NPAS3 |
3.353e-03 | -5.70 | HNRNPL (heterogeneous nuclear ribonucleoprotein L) | protein interactions | 3191 | 1958 | 12 | 19454 | 50 |
NFIA,DCLK2,MACF1,BMPR1B,MSI2,DTNA,TRPS1,ZBTB20,ABLIM1,QKI,PARD3B,NRG3 |
3.356e-03 | -5.70 | Cation_ATPase | pfam domains | PF13246 | 32 | 2 | 17795 | 48 |
ATP1A2,ATP13A4 |
3.371e-03 | -5.69 | middle_third | COSMIC cancer mutations | middle_third | 3533 | 19 | 16828 | 49 |
GPC5,SPARCL1,NHSL1,ADCY2,ABLIM1,MAML2,NRG3,GPM6A,MACF1,ATP1A2,RYR3,NEBL,LRIG1,SASH1,PCDH9,PTPRZ1,SOX5,ZBTB20,CTNND2 |
3.472e-03 | -5.66 | monoatomic ion transmembrane transporter activity | molecular function | GO:0015075 | 752 | 7 | 18094 | 48 |
ITPR2,ATP13A4,SLC1A3,ATP1A2,GPM6A,SLC1A2,RYR3 |
3.479e-03 | -5.66 | positive regulation of cartilage development | biological process | GO:0061036 | 32 | 2 | 18204 | 50 |
BMPR1B,SOX5 |
3.479e-03 | -5.66 | transepithelial transport | biological process | GO:0070633 | 32 | 2 | 18204 | 50 |
SLC1A2,SLC1A3 |
3.621e-03 | -5.62 | serous_carcinoma | COSMIC cancer mutations | serous_carcinoma | 10987 | 41 | 16828 | 49 |
GPC5,SLC1A2,QKI,CDH20,PARD3B,GLIS3,MAML2,NTRK2,MACF1,RYR3,ATP13A4,NEBL,PRKG1,CTNND2,SORBS1,PTPRZ1,LIFR,FBXL7,MSI2,MGAT4C,NRG3,PPP2R2B,DTNA,NHSL1,ADCY2,DCLK2,TRPS1,CSGALNACT1,ATP1A2,LRIG1,BMPR1B,ITPR2,SOX5,ZBTB20,RORA,LSAMP,SLC1A3,SASH1,NTM,PCDH9,NPAS3 |
3.649e-03 | -5.61 | TPRA1 (transmembrane protein adipocyte associated 1) | protein interactions | 131601 | 35 | 2 | 19454 | 50 |
BMPR1B,ITPR2 |
3.688e-03 | -5.60 | calcium channel activity | molecular function | GO:0005262 | 117 | 3 | 18094 | 48 |
ITPR2,RYR3,GPM6A |
3.692e-03 | -5.60 | dendrite development | biological process | GO:0016358 | 113 | 3 | 18204 | 50 |
PRKG1,CTNNA2,CTNND2 |
3.697e-03 | -5.60 | response to auditory stimulus | biological process | GO:0010996 | 33 | 2 | 18204 | 50 |
SLC1A3,ATP1A2 |
3.741e-03 | -5.59 | connective tissue development | biological process | GO:0061448 | 232 | 4 | 18204 | 50 |
SOX5,BMPR1B,CSGALNACT1,NFIA |
3.799e-03 | -5.57 | DAG and IP3 signaling | REACTOME pathways | R-HSA-1489509 | 34 | 2 | 10285 | 28 |
ITPR2,ADCY2 |
3.878e-03 | -5.55 | organic acid:sodium symporter activity | molecular function | GO:0005343 | 35 | 2 | 18094 | 48 |
SLC1A2,SLC1A3 |
3.908e-03 | -5.54 | bone-extraskeletal-Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour | COSMIC cancer mutations | bone-extraskeletal-Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour | 891 | 8 | 16828 | 49 |
NPAS3,PTPRZ1,ABLIM1,PPP2R2B,ITPR2,SPARCL1,ATP1A2,LRIG1 |
3.911e-03 | -5.54 | DELLA | smart domains | SM01129 | 1 | 1 | 9717 | 38 |
MACF1 |
3.912e-03 | -5.54 | Ig_sub2 | interpro domains | IPR003598 | 239 | 4 | 18521 | 50 |
NTRK2,LRIG1,LSAMP,NTM |
3.973e-03 | -5.53 | Sudden Infant Death Syndrome (SIDS) Susceptibility Pathways | WikiPathways | WP706 | 162 | 4 | 5310 | 22 |
NTRK2,AQP4,RORA,SLC1A3 |
4.018e-03 | -5.52 | NTKRECEPTOR2 | prints domains | PR01941 | 1 | 1 | 5227 | 21 |
NTRK2 |
4.018e-03 | -5.52 | AQUAPORIN4 | prints domains | PR02016 | 1 | 1 | 5227 | 21 |
AQP4 |
4.021e-03 | -5.52 | ErbB4 signaling events | Pathway Interaction DB | erbb4_pathway | 32 | 2 | 2226 | 7 |
NRG3,LRIG1 |
4.052e-03 | -5.51 | glial cell projection | cellular component | GO:0097386 | 37 | 2 | 19108 | 49 |
SLC1A2,AQP4 |
4.071e-03 | -5.50 | PADI3 (peptidyl arginine deiminase 3) | protein interactions | 51702 | 37 | 2 | 19454 | 50 |
CSGALNACT1,SPARCL1 |
4.071e-03 | -5.50 | TRNAU1AP (tRNA selenocysteine 1 associated protein 1) | protein interactions | 54952 | 37 | 2 | 19454 | 50 |
QKI,ZBTB20 |
4.094e-03 | -5.50 | transporter activity | molecular function | GO:0005215 | 1211 | 9 | 18094 | 48 |
SLC1A3,GPM6A,ATP1A2,RYR3,SLC1A2,AQP4,PITPNC1,ATP13A4,ITPR2 |
4.233e-03 | -5.46 | SH3 Domains | gene3d domains | 2.30.30.40 | 223 | 4 | 14470 | 43 |
SORBS1,NEBL,MACF1,SASH1 |
4.238e-03 | -5.46 | extraskeletal | COSMIC cancer mutations | extraskeletal | 903 | 8 | 16828 | 49 |
SPARCL1,ITPR2,ATP1A2,LRIG1,NPAS3,PTPRZ1,ABLIM1,PPP2R2B |
4.244e-03 | -5.46 | ATPase_P-typ_P_site | interpro domains | IPR018303 | 36 | 2 | 18521 | 50 |
ATP1A2,ATP13A4 |
4.244e-03 | -5.46 | P_typ_ATPase | interpro domains | IPR001757 | 36 | 2 | 18521 | 50 |
ATP1A2,ATP13A4 |
4.244e-03 | -5.46 | ATPase_P-typ_cyto_dom_N | interpro domains | IPR023299 | 36 | 2 | 18521 | 50 |
ATP1A2,ATP13A4 |
4.244e-03 | -5.46 | P_typ_ATPase_HD_dom | interpro domains | IPR044492 | 36 | 2 | 18521 | 50 |
ATP13A4,ATP1A2 |
4.244e-03 | -5.46 | ATPase_P-typ_transduc_dom_A_sf | interpro domains | IPR008250 | 36 | 2 | 18521 | 50 |
ATP1A2,ATP13A4 |
4.252e-03 | -5.46 | PLC-gamma1 signalling | REACTOME pathways | R-HSA-167021 | 36 | 2 | 10285 | 28 |
ADCY2,ITPR2 |
4.252e-03 | -5.46 | EGFR interacts with phospholipase C-gamma | REACTOME pathways | R-HSA-212718 | 36 | 2 | 10285 | 28 |
ADCY2,ITPR2 |
4.257e-03 | -5.46 | response to endogenous stimulus | biological process | GO:0009719 | 1402 | 10 | 18204 | 50 |
NFIA,BMPR1B,SORBS1,ITPR2,RYR3,NTRK2,SLC1A3,SLC1A2,SOX5,ATP1A2 |
4.258e-03 | -5.46 | PAX9 (paired box 9) | protein interactions | 5083 | 127 | 3 | 19454 | 50 |
NFIA,TRPS1,QKI |
4.258e-03 | -5.46 | EPB41L4A (erythrocyte membrane protein band 4.1 like 4A) | protein interactions | 64097 | 127 | 3 | 19454 | 50 |
ABLIM1,DTNA,MACF1 |
4.290e-03 | -5.45 | Pcbp1 (poly(rC) binding protein 1) | protein interactions | 23983 | 38 | 2 | 19454 | 50 |
MSI2,QKI |
4.335e-03 | -5.44 | kidney-other-neoplasm | COSMIC cancer mutations | kidney-other-neoplasm | 10653 | 40 | 16828 | 49 |
FBXL7,MGAT4C,GPM6A,PPP2R2B,ABLIM1,NRG3,RFX4,NHSL1,ADCY2,DTNA,LRIG1,CSGALNACT1,TRPS1,ATP1A2,ITPR2,RORA,ZBTB20,SOX5,PCDH9,NPAS3,SLC1A3,LSAMP,SASH1,NKAIN3,CDH20,QKI,SPARCL1,SLC1A2,GPC5,NTRK2,MAML2,AQP4,RYR3,ATP13A4,NEBL,MACF1,PRKG1,CTNND2,PTPRZ1,SORBS1 |
4.370e-03 | -5.43 | striated muscle contraction | biological process | GO:0006941 | 120 | 3 | 18204 | 50 |
DTNA,ATP1A2,RYR3 |
4.407e-03 | -5.42 | bone-Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour | COSMIC cancer mutations | bone-Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour | 6023 | 27 | 16828 | 49 |
CTNND2,PTPRZ1,RYR3,NEBL,ATP13A4,MACF1,NTRK2,MAML2,NKAIN3,SPARCL1,GLIS3,RORA,ZBTB20,SOX5,NPAS3,SLC1A3,SASH1,LRIG1,CSGALNACT1,ATP1A2,ITPR2,ABLIM1,NRG3,DCLK2,ADCY2,DTNA,LIFR |
4.432e-03 | -5.42 | chondroitin biosynthesis | BIOCYC pathways | HUMAN_PWY-6566 | 2 | 1 | 902 | 2 |
CSGALNACT1 |
4.448e-03 | -5.42 | central_nervous_system-brainstem-glioma-oligoastrocytoma_Grade_III | COSMIC cancer mutations | central_nervous_system-brainstem-glioma-oligoastrocytoma_Grade_III | 114 | 3 | 16828 | 49 |
RYR3,SOX5,SLC1A2 |
4.448e-03 | -5.42 | Lima1 (LIM domain and actin binding 1) | protein interactions | 65970 | 129 | 3 | 19454 | 50 |
ABLIM1,ITPR2,ZBTB20 |
4.455e-03 | -5.41 | inorganic cation transmembrane transporter activity | molecular function | GO:0022890 | 589 | 6 | 18094 | 48 |
RYR3,ITPR2,SLC1A2,GPM6A,ATP1A2,SLC1A3 |
4.478e-03 | -5.41 | ATPase_P-typ_TM_dom_sf | interpro domains | IPR023298 | 37 | 2 | 18521 | 50 |
ATP13A4,ATP1A2 |
4.605e-03 | -5.38 | positive regulation of neurogenesis | biological process | GO:0050769 | 246 | 4 | 18204 | 50 |
NTRK2,QKI,MACF1,PTPRZ1 |
4.631e-03 | -5.38 | positive regulation of glucose import | biological process | GO:0046326 | 37 | 2 | 18204 | 50 |
SLC1A2,SORBS1 |
4.744e-03 | -5.35 | CTNNBIP1 (catenin beta interacting protein 1) | protein interactions | 56998 | 40 | 2 | 19454 | 50 |
PPP2R2B,CTNNA2 |
4.835e-03 | -5.33 | skin-head_neck-malignant_melanoma-superficial_spreading | COSMIC cancer mutations | skin-head_neck-malignant_melanoma-superficial_spreading | 923 | 8 | 16828 | 49 |
MGAT4C,LIFR,MACF1,ATP13A4,SORBS1,ADCY2,CTNND2,PPP2R2B |
4.868e-03 | -5.33 | dendrite | cellular component | GO:0030425 | 620 | 6 | 19108 | 49 |
ATP1A2,BMPR1B,CTNND2,NTRK2,ADCY2,GPM6A |
4.880e-03 | -5.32 | amino acid import across plasma membrane | biological process | GO:0089718 | 38 | 2 | 18204 | 50 |
SLC1A3,SLC1A2 |
4.944e-03 | -5.31 | dendritic tree | cellular component | GO:0097447 | 622 | 6 | 19108 | 49 |
ADCY2,NTRK2,CTNND2,BMPR1B,ATP1A2,GPM6A |
4.969e-03 | -5.30 | intracellular chemical homeostasis | biological process | GO:0055082 | 581 | 6 | 18204 | 50 |
ATP13A4,ZBTB20,ATP1A2,AQP4,SLC1A3,RYR3 |
5.049e-03 | -5.29 | NTRK2 (neurotrophic receptor tyrosine kinase 2) | protein interactions | 4915 | 135 | 3 | 19454 | 50 |
DTNA,NTRK2,ABLIM1 |
5.049e-03 | -5.29 | Myo1c (myosin IC) | protein interactions | 17913 | 135 | 3 | 19454 | 50 |
ITPR2,ABLIM1,TRPS1 |
5.049e-03 | -5.29 | FOXP1 (forkhead box P1) | protein interactions | 27086 | 135 | 3 | 19454 | 50 |
NFIA,SASH1,SOX5 |
5.097e-03 | -5.28 | Calcium-transporting ATPase, cytoplasmic transduction domain A | gene3d domains | 2.70.150.10 | 36 | 2 | 14470 | 43 |
ATP1A2,ATP13A4 |
5.097e-03 | -5.28 | Calcium-transporting ATPase, cytoplasmic domain N | gene3d domains | 3.40.1110.10 | 36 | 2 | 14470 | 43 |
ATP1A2,ATP13A4 |
5.127e-03 | -5.27 | EF-hand-dom_pair | interpro domains | IPR011992 | 258 | 4 | 18521 | 50 |
RYR3,DTNA,SPARCL1,MACF1 |
5.134e-03 | -5.27 | Fkbp1a (FK506 binding protein 1a) | protein interactions | 14225 | 2 | 1 | 19454 | 50 |
BMPR1B |
5.134e-03 | -5.27 | Klhl1 (kelch-like 1) | protein interactions | 93688 | 2 | 1 | 19454 | 50 |
BMPR1B |
5.134e-03 | -5.27 | TRIM39-RPP21 (TRIM39-RPP21 readthrough) | protein interactions | 202658 | 2 | 1 | 19454 | 50 |
PRKG1 |
5.134e-03 | -5.27 | Mknk2 (MAP kinase-interacting serine/threonine kinase 2) | protein interactions | 17347 | 2 | 1 | 19454 | 50 |
BMPR1B |
5.134e-03 | -5.27 | Zmym2 (zinc finger, MYM-type 2) | protein interactions | 76007 | 2 | 1 | 19454 | 50 |
GLIS3 |
5.134e-03 | -5.27 | Fbxo34 (F-box protein 34) | protein interactions | 78938 | 2 | 1 | 19454 | 50 |
BMPR1B |
5.134e-03 | -5.27 | Bcr (BCR activator of RhoGEF and GTPase) | protein interactions | 110279 | 2 | 1 | 19454 | 50 |
BMPR1B |
5.134e-03 | -5.27 | Ppp3cc (protein phosphatase 3, catalytic subunit, gamma isoform) | protein interactions | 19057 | 2 | 1 | 19454 | 50 |
BMPR1B |
5.134e-03 | -5.27 | Fkbp1b (FK506 binding protein 1b) | protein interactions | 14226 | 2 | 1 | 19454 | 50 |
BMPR1B |
5.134e-03 | -5.27 | Bmpr2 (bone morphogenetic protein receptor type 2) | protein interactions | 12168 | 2 | 1 | 19454 | 50 |
BMPR1B |
5.134e-03 | -5.27 | Sh3kbp1 (SH3-domain kinase binding protein 1) | protein interactions | 58194 | 2 | 1 | 19454 | 50 |
BMPR1B |
5.134e-03 | -5.27 | Irf7 (interferon regulatory factor 7) | protein interactions | 54123 | 2 | 1 | 19454 | 50 |
BMPR1B |
5.134e-03 | -5.27 | Kdm4c (lysine (K)-specific demethylase 4C) | protein interactions | 76804 | 2 | 1 | 19454 | 50 |
GLIS3 |
5.134e-03 | -5.27 | sodium ion homeostasis | biological process | GO:0055078 | 39 | 2 | 18204 | 50 |
SLC1A3,ATP1A2 |
5.157e-03 | -5.27 | ovary-carcinoma | COSMIC cancer mutations | ovary-carcinoma | 933 | 8 | 16828 | 49 |
NTRK2,PPP2R2B,DCLK2,ATP1A2,MACF1,BMPR1B,PRKG1,ITPR2 |
5.157e-03 | -5.27 | animal organ morphogenesis | biological process | GO:0009887 | 988 | 8 | 18204 | 50 |
BMPR1B,LRIG1,CSGALNACT1,CTNNA2,SOX5,ABLIM1,NTRK2,NRG3 |
5.299e-03 | -5.24 | cGMP-dependent protein kinase activity | molecular function | GO:0004692 | 2 | 1 | 18094 | 48 |
PRKG1 |
5.299e-03 | -5.24 | leukemia inhibitory factor receptor activity | molecular function | GO:0004923 | 2 | 1 | 18094 | 48 |
LIFR |
5.366e-03 | -5.23 | NFIB (nuclear factor I B) | protein interactions | 4781 | 138 | 3 | 19454 | 50 |
SOX5,TRPS1,NFIA |
5.377e-03 | -5.23 | somatodendritic compartment | cellular component | GO:0036477 | 842 | 7 | 19108 | 49 |
SLC1A3,GPM6A,BMPR1B,NTRK2,ADCY2,CTNND2,ATP1A2 |
5.388e-03 | -5.22 | LIF-R_Ig-like | pfam domains | PF21177 | 2 | 1 | 17795 | 48 |
LIFR |
5.388e-03 | -5.22 | Par3_HAL_N_term | pfam domains | PF12053 | 2 | 1 | 17795 | 48 |
PARD3B |
5.388e-03 | -5.22 | LIFR_D2 | pfam domains | PF17971 | 2 | 1 | 17795 | 48 |
LIFR |
5.392e-03 | -5.22 | LIF-R-like_Ig-like | interpro domains | IPR048497 | 2 | 1 | 18521 | 50 |
LIFR |
5.392e-03 | -5.22 | Osteonectin_CS | interpro domains | IPR001999 | 2 | 1 | 18521 | 50 |
SPARCL1 |
5.392e-03 | -5.22 | Alpha_CARP_receptor-type | interpro domains | IPR041887 | 2 | 1 | 18521 | 50 |
PTPRZ1 |
5.392e-03 | -5.22 | LIFR_D2 | interpro domains | IPR040817 | 2 | 1 | 18521 | 50 |
LIFR |
5.392e-03 | -5.22 | MSI_RRM2 | interpro domains | IPR034126 | 2 | 1 | 18521 | 50 |
MSI2 |
5.392e-03 | -5.22 | Par3/HAL_N | interpro domains | IPR021922 | 2 | 1 | 18521 | 50 |
PARD3B |
5.392e-03 | -5.22 | Distrobrevin | interpro domains | IPR017432 | 2 | 1 | 18521 | 50 |
DTNA |
5.392e-03 | -5.22 | cGMP_dep_kinase | interpro domains | IPR002374 | 2 | 1 | 18521 | 50 |
PRKG1 |
5.392e-03 | -5.22 | STKc_cGK | interpro domains | IPR035014 | 2 | 1 | 18521 | 50 |
PRKG1 |
5.395e-03 | -5.22 | cyclic purine nucleotide metabolic process | biological process | GO:0052652 | 40 | 2 | 18204 | 50 |
ADCY2,RORA |
5.440e-03 | -5.21 | sarcoplasmic reticulum membrane | cellular component | GO:0033017 | 43 | 2 | 19108 | 49 |
ITPR2,RYR3 |
5.462e-03 | -5.21 | lung-carcinoma-adenocarcinoma | COSMIC cancer mutations | lung-carcinoma-adenocarcinoma | 15133 | 49 | 16828 | 49 |
LRIG1,ATP1A2,CSGALNACT1,RORA,SOX5,ZBTB20,NTM,SASH1,MGAT4C,PPP2R2B,GPM6A,RFX4,DCLK2,ADCY2,ATP13A4,MACF1,PRKG1,SORBS1,QKI,CDH20,GPC5,AQP4,MAML2,TRPS1,ITPR2,BMPR1B,NPAS3,PCDH9,SLC1A3,LSAMP,FBXL7,LIFR,NFIA,MSI2,NRG3,ABLIM1,NHSL1,DTNA,NEBL,RYR3,CTNND2,PTPRZ1,NKAIN3,PITPNC1,PARD3B,SPARCL1,GLIS3,SLC1A2,NTRK2 |
5.486e-03 | -5.21 | UDP-glucuronate metabolic process | biological process | GO:0046398 | 2 | 1 | 18204 | 50 |
CSGALNACT1 |
5.486e-03 | -5.21 | negative regulation of inositol phosphate biosynthetic process | biological process | GO:0010920 | 2 | 1 | 18204 | 50 |
PRKG1 |
5.486e-03 | -5.21 | myofibroblast contraction | biological process | GO:1990764 | 2 | 1 | 18204 | 50 |
QKI |
5.486e-03 | -5.21 | negative regulation of 3'-UTR-mediated mRNA stabilization | biological process | GO:1905869 | 2 | 1 | 18204 | 50 |
QKI |
5.486e-03 | -5.21 | chondroitin sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process | biological process | GO:0050653 | 2 | 1 | 18204 | 50 |
CSGALNACT1 |
5.545e-03 | -5.19 | neutral L-amino acid transmembrane transporter activity | molecular function | GO:0015175 | 42 | 2 | 18094 | 48 |
SLC1A2,SLC1A3 |
5.612e-03 | -5.18 | calcium ion transmembrane transporter activity | molecular function | GO:0015085 | 136 | 3 | 18094 | 48 |
GPM6A,RYR3,ITPR2 |
5.662e-03 | -5.17 | cyclic nucleotide metabolic process | biological process | GO:0009187 | 41 | 2 | 18204 | 50 |
ADCY2,RORA |
5.692e-03 | -5.17 | actin binding | molecular function | GO:0003779 | 434 | 5 | 18094 | 48 |
SORBS1,CTNNA2,NEBL,ABLIM1,MACF1 |
5.697e-03 | -5.17 | amino acid transport | biological process | GO:0006865 | 132 | 3 | 18204 | 50 |
SLC1A2,NTRK2,SLC1A3 |
5.732e-03 | -5.16 | Vascular smooth muscle contraction | KEGG pathways | ko04270 | 121 | 3 | 7161 | 22 |
PRKG1,ADCY2,ITPR2 |
5.732e-03 | -5.16 | Vascular smooth muscle contraction | KEGG pathways | hsa04270 | 121 | 3 | 7161 | 22 |
PRKG1,ITPR2,ADCY2 |
5.755e-03 | -5.16 | clear_cell_renal_cell_carcinoma | COSMIC cancer mutations | clear_cell_renal_cell_carcinoma | 13924 | 47 | 16828 | 49 |
NTRK2,PITPNC1,NKAIN3,SLC1A2,GLIS3,SPARCL1,PARD3B,CTNND2,PTPRZ1,RYR3,NEBL,ABLIM1,NRG3,DTNA,NHSL1,NFIA,LIFR,FBXL7,MSI2,SLC1A3,LSAMP,PCDH9,NPAS3,TRPS1,BMPR1B,ITPR2,MAML2,AQP4,GPC5,QKI,CDH20,SORBS1,MACF1,ATP13A4,PRKG1,GPM6A,PPP2R2B,DCLK2,ADCY2,MGAT4C,SOX5,ZBTB20,RORA,SASH1,CSGALNACT1,ATP1A2,LRIG1 |
5.755e-03 | -5.16 | kidney-carcinoma-clear_cell_renal_cell_carcinoma | COSMIC cancer mutations | kidney-carcinoma-clear_cell_renal_cell_carcinoma | 13924 | 47 | 16828 | 49 |
NEBL,RYR3,PTPRZ1,CTNND2,SPARCL1,GLIS3,PARD3B,SLC1A2,PITPNC1,NKAIN3,NTRK2,ITPR2,BMPR1B,TRPS1,PCDH9,NPAS3,LSAMP,SLC1A3,MSI2,FBXL7,NFIA,LIFR,NHSL1,DTNA,NRG3,ABLIM1,PRKG1,ATP13A4,MACF1,SORBS1,QKI,CDH20,GPC5,AQP4,MAML2,LRIG1,ATP1A2,CSGALNACT1,SASH1,RORA,SOX5,ZBTB20,MGAT4C,DCLK2,ADCY2,PPP2R2B,GPM6A |
5.817e-03 | -5.15 | regulation of sequestering of calcium ion | biological process | GO:0051282 | 133 | 3 | 18204 | 50 |
ATP1A2,ITPR2,RYR3 |
5.885e-03 | -5.14 | central_nervous_system-brain-glioma-oligodendroglioma_Grade_III | COSMIC cancer mutations | central_nervous_system-brain-glioma-oligodendroglioma_Grade_III | 249 | 4 | 16828 | 49 |
PTPRZ1,MGAT4C,GLIS3,MACF1 |
5.935e-03 | -5.13 | active monoatomic ion transmembrane transporter activity | molecular function | GO:0022853 | 274 | 4 | 18094 | 48 |
SLC1A3,ATP1A2,SLC1A2,ATP13A4 |
5.935e-03 | -5.13 | Vinculin, Vh2 four-helix bundle | gene3d domains | 1.20.120.810 | 2 | 1 | 14470 | 43 |
CTNNA2 |
5.935e-03 | -5.13 | - | gene3d domains | 6.20.350.10 | 2 | 1 | 14470 | 43 |
RYR3 |
5.935e-03 | -5.13 | regulation of amino acid transport | biological process | GO:0051955 | 42 | 2 | 18204 | 50 |
PRKG1,ATP1A2 |
5.944e-03 | -5.13 | ductolobular_carcinoma | COSMIC cancer mutations | ductolobular_carcinoma | 1619 | 11 | 16828 | 49 |
MACF1,CTNND2,RORA,SORBS1,PTPRZ1,LIFR,PARD3B,CDH20,QKI,ABLIM1,DTNA |
5.944e-03 | -5.13 | breast-carcinoma-ductolobular_carcinoma | COSMIC cancer mutations | breast-carcinoma-ductolobular_carcinoma | 1619 | 11 | 16828 | 49 |
ABLIM1,DTNA,LIFR,PARD3B,CDH20,QKI,RORA,CTNND2,PTPRZ1,SORBS1,MACF1 |
5.997e-03 | -5.12 | FLOT1 (flotillin 1) | protein interactions | 10211 | 453 | 5 | 19454 | 50 |
DTNA,MACF1,SOX5,ABLIM1,SORBS1 |
5.998e-03 | -5.12 | cellular response to organic substance | biological process | GO:0071310 | 1716 | 11 | 18204 | 50 |
LIFR,SLC1A3,RYR3,RORA,ADCY2,SLC1A2,AQP4,ZBTB20,ATP1A2,ITPR2,SORBS1 |
6.000e-03 | -5.12 | Platelet activation | KEGG pathways | hsa04611 | 123 | 3 | 7161 | 22 |
PRKG1,ADCY2,ITPR2 |
6.001e-03 | -5.12 | YWHAH (tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein eta) | protein interactions | 7533 | 1083 | 8 | 19454 | 50 |
MACF1,DCLK2,PITPNC1,PARD3B,NHSL1,SASH1,ABLIM1,SORBS1 |
6.024e-03 | -5.11 | Vasopressin regulates renal water homeostasis via Aquaporins | REACTOME pathways | R-HSA-432040 | 43 | 2 | 10285 | 28 |
AQP4,ADCY2 |
6.037e-03 | -5.11 | Calml3 (calmodulin-like 3) | protein interactions | 70405 | 144 | 3 | 19454 | 50 |
ABLIM1,ZBTB20,MACF1 |
6.090e-03 | -5.10 | monoatomic ion transmembrane transport | biological process | GO:0034220 | 804 | 7 | 18204 | 50 |
ATP1A2,RYR3,GPM6A,SLC1A2,SLC1A3,ITPR2,ATP13A4 |
6.107e-03 | -5.10 | axon | cellular component | GO:0030424 | 650 | 6 | 19108 | 49 |
DTNA,SLC1A2,CTNNA2,GPM6A,PCDH9,NTRK2 |
6.211e-03 | -5.08 | adrenal_gland | COSMIC cancer mutations | adrenal_gland | 2628 | 15 | 16828 | 49 |
PTPRZ1,PCDH9,CTNND2,ZBTB20,SOX5,LRIG1,ATP1A2,CSGALNACT1,ADCY2,NHSL1,NTRK2,RFX4,NRG3,MAML2,SLC1A2 |
6.272e-03 | -5.07 | PARD3 (par-3 family cell polarity regulator) | protein interactions | 56288 | 287 | 4 | 19454 | 50 |
SORBS1,DTNA,NTRK2,PARD3B |
6.348e-03 | -5.06 | VASP (vasodilator stimulated phosphoprotein) | protein interactions | 7408 | 288 | 4 | 19454 | 50 |
PRKG1,NHSL1,SORBS1,NEBL |
6.372e-03 | -5.06 | acute_myeloid_leukaemia | COSMIC cancer mutations | acute_myeloid_leukaemia | 10418 | 39 | 16828 | 49 |
LRIG1,CSGALNACT1,ATP1A2,ITPR2,RORA,SOX5,PCDH9,NPAS3,NTM,SLC1A3,LSAMP,SASH1,NFIA,LIFR,FBXL7,MSI2,PPP2R2B,ABLIM1,NRG3,RFX4,ADCY2,NHSL1,RYR3,NEBL,ATP13A4,MACF1,PRKG1,CTNND2,PTPRZ1,NKAIN3,QKI,CDH20,SPARCL1,GLIS3,PARD3B,SLC1A2,GPC5,NTRK2,MAML2 |
6.372e-03 | -5.06 | haematopoietic_and_lymphoid_tissue-haematopoietic_neoplasm-acute_myeloid_leukaemia | COSMIC cancer mutations | haematopoietic_and_lymphoid_tissue-haematopoietic_neoplasm-acute_myeloid_leukaemia | 10418 | 39 | 16828 | 49 |
ABLIM1,RFX4,NRG3,PPP2R2B,NHSL1,ADCY2,LIFR,NFIA,FBXL7,MSI2,SOX5,RORA,LSAMP,SLC1A3,SASH1,NPAS3,NTM,PCDH9,CSGALNACT1,ATP1A2,LRIG1,ITPR2,MAML2,NTRK2,NKAIN3,SLC1A2,GPC5,CDH20,QKI,SPARCL1,PARD3B,GLIS3,CTNND2,PTPRZ1,MACF1,RYR3,NEBL,ATP13A4,PRKG1 |
6.441e-03 | -5.05 | membrane raft | cellular component | GO:0045121 | 290 | 4 | 19108 | 49 |
ADCY2,SLC1A2,ATP1A2,SORBS1 |
6.492e-03 | -5.04 | Ig_3 | pfam domains | PF13927 | 141 | 3 | 17795 | 48 |
LRIG1,NTM,LSAMP |
6.493e-03 | -5.04 | spleen | COSMIC cancer mutations | spleen | 408 | 5 | 16828 | 49 |
ADCY2,PARD3B,NTM,PTPRZ1,SORBS1 |
6.498e-03 | -5.04 | positive regulation of glucose transmembrane transport | biological process | GO:0010828 | 44 | 2 | 18204 | 50 |
SLC1A2,SORBS1 |
6.500e-03 | -5.04 | CNTN1 (contactin 1) | protein interactions | 1272 | 47 | 2 | 19454 | 50 |
GPM6A,PTPRZ1 |
6.557e-03 | -5.03 | Cardiac conduction | REACTOME pathways | R-HSA-5576891 | 142 | 3 | 10285 | 28 |
ATP1A2,ITPR2,RYR3 |
6.597e-03 | -5.02 | membrane microdomain | cellular component | GO:0098857 | 292 | 4 | 19108 | 49 |
SORBS1,ATP1A2,SLC1A2,ADCY2 |
6.599e-03 | -5.02 | SOX2 (SRY-box transcription factor 2) | protein interactions | 6657 | 1342 | 9 | 19454 | 50 |
MACF1,TRPS1,GLIS3,NFIA,QKI,SOX5,MSI2,ITPR2,LSAMP |
6.634e-03 | -5.02 | vascular process in circulatory system | biological process | GO:0003018 | 273 | 4 | 18204 | 50 |
PRKG1,ATP1A2,SLC1A3,SLC1A2 |
6.702e-03 | -5.01 | neurotransmitter transport | biological process | GO:0006836 | 140 | 3 | 18204 | 50 |
ATP1A2,SLC1A3,SLC1A2 |
6.804e-03 | -4.99 | gliogenesis | biological process | GO:0042063 | 275 | 4 | 18204 | 50 |
NTRK2,QKI,PTPRZ1,NFIA |
6.941e-03 | -4.97 | bronchioloalveolar_adenocarcinoma | COSMIC cancer mutations | bronchioloalveolar_adenocarcinoma | 778 | 7 | 16828 | 49 |
NTRK2,SOX5,CTNND2,DCLK2,ADCY2,PRKG1,BMPR1B |
6.941e-03 | -4.97 | lung-carcinoma-bronchioloalveolar_adenocarcinoma | COSMIC cancer mutations | lung-carcinoma-bronchioloalveolar_adenocarcinoma | 778 | 7 | 16828 | 49 |
SOX5,CTNND2,NTRK2,DCLK2,ADCY2,PRKG1,BMPR1B |
6.969e-03 | -4.97 | neuron migration | biological process | GO:0001764 | 142 | 3 | 18204 | 50 |
GPM6A,NTRK2,PRKG1 |
7.045e-03 | -4.96 | OSTEONECTIN_1 | prosite domains | PS00612 | 2 | 1 | 12186 | 43 |
SPARCL1 |
7.045e-03 | -4.96 | OSTEONECTIN_2 | prosite domains | PS00613 | 2 | 1 | 12186 | 43 |
SPARCL1 |
7.064e-03 | -4.95 | SP7 (Sp7 transcription factor) | protein interactions | 121340 | 297 | 4 | 19454 | 50 |
QKI,SOX5,TRPS1,NFIA |
7.084e-03 | -4.95 | positive regulation of glial cell differentiation | biological process | GO:0045687 | 46 | 2 | 18204 | 50 |
PTPRZ1,QKI |
7.084e-03 | -4.95 | regulation of oligodendrocyte differentiation | biological process | GO:0048713 | 46 | 2 | 18204 | 50 |
QKI,PTPRZ1 |
7.095e-03 | -4.95 | enzyme-linked receptor protein signaling pathway | biological process | GO:0007167 | 626 | 6 | 18204 | 50 |
NRG3,SORBS1,BMPR1B,NTRK2,NFIA,LIFR |
7.101e-03 | -4.95 | ATPASE_E1_E2 | prosite domains | PS00154 | 36 | 2 | 12186 | 43 |
ATP13A4,ATP1A2 |
7.116e-03 | -4.95 | nasopharyngeal_carcinoma | COSMIC cancer mutations | nasopharyngeal_carcinoma | 1425 | 10 | 16828 | 49 |
NHSL1,NTRK2,CTNND2,RFX4,QKI,SLC1A2,ATP13A4,NFIA,PITPNC1,ATP1A2 |
7.116e-03 | -4.95 | upper_aerodigestive_tract-pharynx-carcinoma-nasopharyngeal_carcinoma | COSMIC cancer mutations | upper_aerodigestive_tract-pharynx-carcinoma-nasopharyngeal_carcinoma | 1425 | 10 | 16828 | 49 |
ATP13A4,ATP1A2,PITPNC1,NFIA,QKI,SLC1A2,NTRK2,RFX4,CTNND2,NHSL1 |
7.135e-03 | -4.94 | SOX6 (SRY-box transcription factor 6) | protein interactions | 55553 | 153 | 3 | 19454 | 50 |
TRPS1,NFIA,SOX5 |
7.163e-03 | -4.94 | PLC beta mediated events | REACTOME pathways | R-HSA-112043 | 47 | 2 | 10285 | 28 |
ADCY2,ITPR2 |
7.213e-03 | -4.93 | system process | biological process | GO:0003008 | 2015 | 12 | 18204 | 50 |
RYR3,NTRK2,SLC1A3,ABLIM1,PTPRZ1,PRKG1,DTNA,ATP1A2,AQP4,SLC1A2,CTNNA2,LRIG1 |
7.263e-03 | -4.93 | cellular response to oxygen-containing compound | biological process | GO:1901701 | 1047 | 8 | 18204 | 50 |
SLC1A2,SLC1A3,RYR3,ZBTB20,RORA,ADCY2,ITPR2,SORBS1 |
7.386e-03 | -4.91 | regulation of neuron migration | biological process | GO:2001222 | 47 | 2 | 18204 | 50 |
CTNNA2,NRG3 |
7.394e-03 | -4.91 | PPP2R2D (protein phosphatase 2 regulatory subunit Bdelta) | protein interactions | 55844 | 155 | 3 | 19454 | 50 |
CSGALNACT1,GPC5,PPP2R2B |
7.462e-03 | -4.90 | G-protein mediated events | REACTOME pathways | R-HSA-112040 | 48 | 2 | 10285 | 28 |
ITPR2,ADCY2 |
7.588e-03 | -4.88 | SH3 | prosite domains | PS50002 | 222 | 4 | 12186 | 43 |
NEBL,SORBS1,SASH1,MACF1 |
7.592e-03 | -4.88 | haematopoietic_and_lymphoid_tissue-small_intestine-lymphoid_neoplasm-enteropathy_type_T_cell_lymphoma | COSMIC cancer mutations | haematopoietic_and_lymphoid_tissue-small_intestine-lymphoid_neoplasm-enteropathy_type_T_cell_lymphoma | 45 | 2 | 16828 | 49 |
MGAT4C,MACF1 |
7.592e-03 | -4.88 | enteropathy_type_T_cell_lymphoma | COSMIC cancer mutations | enteropathy_type_T_cell_lymphoma | 45 | 2 | 16828 | 49 |
MGAT4C,MACF1 |
7.617e-03 | -4.88 | Ndc80 (NDC80 kinetochore complex component) | protein interactions | 67052 | 51 | 2 | 19454 | 50 |
MACF1,NHSL1 |
7.631e-03 | -4.88 | human chr8q23.3 | chromosome location | human chr8q23.3 | 4 | 1 | 26134 | 50 |
TRPS1 |
7.646e-03 | -4.87 | monoatomic cation transmembrane transport | biological process | GO:0098655 | 636 | 6 | 18204 | 50 |
RYR3,SLC1A3,GPM6A,ATP1A2,ATP13A4,ITPR2 |
7.691e-03 | -4.87 | Plekhb1 (pleckstrin homology domain containing, family B (evectins) member 1) | protein interactions | 27276 | 3 | 1 | 19454 | 50 |
BMPR1B |
7.691e-03 | -4.87 | Rap2a (RAS related protein 2a) | protein interactions | 76108 | 3 | 1 | 19454 | 50 |
BMPR1B |
7.691e-03 | -4.87 | BCO1 (beta-carotene oxygenase 1) | protein interactions | 53630 | 3 | 1 | 19454 | 50 |
ABLIM1 |
7.691e-03 | -4.87 | Stk35 (serine/threonine kinase 35) | protein interactions | 67333 | 3 | 1 | 19454 | 50 |
BMPR1B |
7.691e-03 | -4.87 | Atg16l1 (autophagy related 16 like 1) | protein interactions | 77040 | 3 | 1 | 19454 | 50 |
BMPR1B |
7.691e-03 | -4.87 | Usp45 (ubiquitin specific petidase 45) | protein interactions | 77593 | 3 | 1 | 19454 | 50 |
BMPR1B |
7.691e-03 | -4.87 | Chn1 (chimerin 1) | protein interactions | 108699 | 3 | 1 | 19454 | 50 |
BMPR1B |
7.691e-03 | -4.87 | Spop (speckle-type BTB/POZ protein) | protein interactions | 20747 | 3 | 1 | 19454 | 50 |
GLIS3 |
7.691e-03 | -4.87 | QRFPR (pyroglutamylated RFamide peptide receptor) | protein interactions | 84109 | 3 | 1 | 19454 | 50 |
NTM |
7.691e-03 | -4.87 | Smad6 (SMAD family member 6) | protein interactions | 17130 | 3 | 1 | 19454 | 50 |
BMPR1B |
7.691e-03 | -4.87 | IL34 (interleukin 34) | protein interactions | 146433 | 3 | 1 | 19454 | 50 |
PTPRZ1 |
7.691e-03 | -4.87 | Fbxw5 (F-box and WD-40 domain protein 5) | protein interactions | 30839 | 3 | 1 | 19454 | 50 |
BMPR1B |
7.700e-03 | -4.87 | cell junction assembly | biological process | GO:0034329 | 285 | 4 | 18204 | 50 |
NRG3,SORBS1,GPM6A,CDH20 |
7.762e-03 | -4.86 | anchoring junction | cellular component | GO:0070161 | 902 | 7 | 19108 | 49 |
CTNNA2,SORBS1,CDH20,PARD3B,PCDH9,CTNND2,ATP1A2 |
7.832e-03 | -4.85 | response to organic cyclic compound | biological process | GO:0014070 | 843 | 7 | 18204 | 50 |
ATP1A2,SLC1A2,SLC1A3,RYR3,ITPR2,ADCY2,RORA |
7.909e-03 | -4.84 | SH2B2 (SH2B adaptor protein 2) | protein interactions | 10603 | 52 | 2 | 19454 | 50 |
NTRK2,SORBS1 |
7.938e-03 | -4.84 | cysteine transmembrane transporter activity | molecular function | GO:0033229 | 3 | 1 | 18094 | 48 |
SLC1A2 |
7.938e-03 | -4.84 | inositol 1,4,5-trisphosphate-gated calcium channel activity | molecular function | GO:0005220 | 3 | 1 | 18094 | 48 |
ITPR2 |
7.938e-03 | -4.84 | glucuronylgalactosylproteoglycan 4-beta-N-acetylgalactosaminyltransferase activity | molecular function | GO:0047237 | 3 | 1 | 18094 | 48 |
CSGALNACT1 |
7.938e-03 | -4.84 | oncostatin-M receptor activity | molecular function | GO:0004924 | 3 | 1 | 18094 | 48 |
LIFR |
7.938e-03 | -4.84 | alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity | molecular function | GO:0008454 | 3 | 1 | 18094 | 48 |
MGAT4C |
8.020e-03 | -4.83 | CGMPKINASE | prints domains | PR00104 | 2 | 1 | 5227 | 21 |
PRKG1 |
8.065e-03 | -4.82 | SOX5 (SRY-box transcription factor 5) | protein interactions | 6660 | 160 | 3 | 19454 | 50 |
TRPS1,NFIA,SOX5 |
8.071e-03 | -4.82 | MamL-1 | pfam domains | PF09596 | 3 | 1 | 17795 | 48 |
MAML2 |
8.071e-03 | -4.82 | LRRCT_2 | pfam domains | PF16920 | 3 | 1 | 17795 | 48 |
NTRK2 |
8.071e-03 | -4.82 | Sorb | pfam domains | PF02208 | 3 | 1 | 17795 | 48 |
SORBS1 |
8.071e-03 | -4.82 | RR_TM4-6 | pfam domains | PF06459 | 3 | 1 | 17795 | 48 |
RYR3 |
8.071e-03 | -4.82 | RYDR_Jsol | pfam domains | PF21119 | 3 | 1 | 17795 | 48 |
RYR3 |
8.071e-03 | -4.82 | SR_plectin_7 | pfam domains | PF21097 | 3 | 1 | 17795 | 48 |
MACF1 |
8.071e-03 | -4.82 | Myelin_PLP | pfam domains | PF01275 | 3 | 1 | 17795 | 48 |
GPM6A |
8.071e-03 | -4.82 | SLY | pfam domains | PF12485 | 3 | 1 | 17795 | 48 |
SASH1 |
8.071e-03 | -4.82 | RyR | pfam domains | PF02026 | 3 | 1 | 17795 | 48 |
RYR3 |
8.078e-03 | -4.82 | Neuregulin | interpro domains | IPR040180 | 3 | 1 | 18521 | 50 |
NRG3 |
8.078e-03 | -4.82 | Myelin_PLP_CS | interpro domains | IPR018237 | 3 | 1 | 18521 | 50 |
GPM6A |
8.078e-03 | -4.82 | MAML1-3 | interpro domains | IPR046369 | 3 | 1 | 18521 | 50 |
MAML2 |
8.078e-03 | -4.82 | InsP3_rcpt | interpro domains | IPR000493 | 3 | 1 | 18521 | 50 |
ITPR2 |
8.078e-03 | -4.82 | Vinculin_CS | interpro domains | IPR000633 | 3 | 1 | 18521 | 50 |
CTNNA2 |
8.078e-03 | -4.82 | Ryan_recept | interpro domains | IPR013333 | 3 | 1 | 18521 | 50 |
RYR3 |
8.078e-03 | -4.82 | Mastermind-like_N | interpro domains | IPR019082 | 3 | 1 | 18521 | 50 |
MAML2 |
8.078e-03 | -4.82 | MAML_N_sf | interpro domains | IPR046370 | 3 | 1 | 18521 | 50 |
MAML2 |
8.078e-03 | -4.82 | NTRK | interpro domains | IPR020777 | 3 | 1 | 18521 | 50 |
NTRK2 |
8.078e-03 | -4.82 | RYDR_Jsol | interpro domains | IPR048581 | 3 | 1 | 18521 | 50 |
RYR3 |
8.078e-03 | -4.82 | SPRY3_RyR | interpro domains | IPR035762 | 3 | 1 | 18521 | 50 |
RYR3 |
8.078e-03 | -4.82 | Ryanrecept_TM4-6 | interpro domains | IPR009460 | 3 | 1 | 18521 | 50 |
RYR3 |
8.078e-03 | -4.82 | Ryanodine_rcpt | interpro domains | IPR003032 | 3 | 1 | 18521 | 50 |
RYR3 |
8.078e-03 | -4.82 | SPIDER | interpro domains | IPR021090 | 3 | 1 | 18521 | 50 |
SASH1 |
8.078e-03 | -4.82 | NTRK_LRRCT | interpro domains | IPR031635 | 3 | 1 | 18521 | 50 |
NTRK2 |
8.078e-03 | -4.82 | SPRY2_RyR | interpro domains | IPR035764 | 3 | 1 | 18521 | 50 |
RYR3 |
8.078e-03 | -4.82 | ROR_rcpt | interpro domains | IPR003079 | 3 | 1 | 18521 | 50 |
RORA |
8.078e-03 | -4.82 | NR_DBD_ROR | interpro domains | IPR044101 | 3 | 1 | 18521 | 50 |
RORA |
8.078e-03 | -4.82 | Myelin_PLP | interpro domains | IPR001614 | 3 | 1 | 18521 | 50 |
GPM6A |
8.078e-03 | -4.82 | SPRY1_RyR | interpro domains | IPR035761 | 3 | 1 | 18521 | 50 |
RYR3 |
8.078e-03 | -4.82 | SoHo_dom | interpro domains | IPR003127 | 3 | 1 | 18521 | 50 |
SORBS1 |
8.079e-03 | -4.82 | muscle cell differentiation | biological process | GO:0042692 | 289 | 4 | 18204 | 50 |
RORA,PRKG1,QKI,NEBL |
8.124e-03 | -4.81 | neuronal cell body | cellular component | GO:0043025 | 489 | 5 | 19108 | 49 |
GPM6A,SLC1A3,BMPR1B,ATP1A2,CTNND2 |
8.218e-03 | -4.80 | cardiac muscle thin filament assembly | biological process | GO:0071691 | 3 | 1 | 18204 | 50 |
NEBL |
8.218e-03 | -4.80 | regulation of calcium:sodium antiporter activity | biological process | GO:1903279 | 3 | 1 | 18204 | 50 |
ATP1A2 |
8.218e-03 | -4.80 | cysteine transport | biological process | GO:0042883 | 3 | 1 | 18204 | 50 |
SLC1A2 |
8.218e-03 | -4.80 | radial glia guided migration of Purkinje cell | biological process | GO:0021942 | 3 | 1 | 18204 | 50 |
CTNNA2 |
8.218e-03 | -4.80 | mammary placode formation | biological process | GO:0060596 | 3 | 1 | 18204 | 50 |
NRG3 |
8.218e-03 | -4.80 | cysteine transmembrane transport | biological process | GO:1903712 | 3 | 1 | 18204 | 50 |
SLC1A2 |
8.218e-03 | -4.80 | trans-synaptic signaling by BDNF, modulating synaptic transmission | biological process | GO:0099183 | 3 | 1 | 18204 | 50 |
NTRK2 |
8.218e-03 | -4.80 | UDP-N-acetylgalactosamine metabolic process | biological process | GO:0019276 | 3 | 1 | 18204 | 50 |
CSGALNACT1 |
8.244e-03 | -4.80 | transmembrane transporter activity | molecular function | GO:0022857 | 1110 | 8 | 18094 | 48 |
ATP1A2,GPM6A,SLC1A2,RYR3,SLC1A3,ITPR2,ATP13A4,AQP4 |
8.247e-03 | -4.80 | Apelin signaling pathway | KEGG pathways | hsa04371 | 138 | 3 | 7161 | 22 |
ITPR2,RYR3,ADCY2 |
8.301e-03 | -4.79 | breast-carcinoma-basal_(triple-negative)_carcinoma | COSMIC cancer mutations | breast-carcinoma-basal_(triple-negative)_carcinoma | 2981 | 16 | 16828 | 49 |
ADCY2,MAML2,NRG3,PPP2R2B,NTRK2,MSI2,SPARCL1,LIFR,SASH1,NPAS3,NTM,PRKG1,BMPR1B,MACF1,ATP1A2,NEBL |
8.301e-03 | -4.79 | basal_(triple-negative)_carcinoma | COSMIC cancer mutations | basal_(triple-negative)_carcinoma | 2981 | 16 | 16828 | 49 |
MAML2,NRG3,PPP2R2B,NTRK2,ADCY2,LIFR,MSI2,SPARCL1,SASH1,NPAS3,NTM,MACF1,ATP1A2,NEBL,PRKG1,BMPR1B |
8.392e-03 | -4.78 | Chondroitin sulfate/dermatan sulfate metabolism | REACTOME pathways | R-HSA-1793185 | 51 | 2 | 10285 | 28 |
CSGALNACT1,GPC5 |
8.392e-03 | -4.78 | Neurotransmitter Release Cycle | REACTOME pathways | R-HSA-112310 | 51 | 2 | 10285 | 28 |
SLC1A3,SLC1A2 |
8.446e-03 | -4.77 | CATATPASE | prints domains | PR00119 | 35 | 2 | 5227 | 21 |
ATP1A2,ATP13A4 |
8.476e-03 | -4.77 | sodium ion transmembrane transporter activity | molecular function | GO:0015081 | 158 | 3 | 18094 | 48 |
ATP1A2,SLC1A2,SLC1A3 |
8.478e-03 | -4.77 | EF-hand | gene3d domains | 1.10.238.10 | 272 | 4 | 14470 | 43 |
DTNA,RYR3,MACF1,SPARCL1 |
8.507e-03 | -4.77 | TAFA4 (TAFA chemokine like family member 4) | protein interactions | 151647 | 54 | 2 | 19454 | 50 |
ITPR2,LIFR |
8.507e-03 | -4.77 | SYNM (synemin) | protein interactions | 23336 | 54 | 2 | 19454 | 50 |
DTNA,PPP2R2B |
8.702e-03 | -4.74 | hindbrain development | biological process | GO:0030902 | 154 | 3 | 18204 | 50 |
PRKG1,RORA,CTNNA2 |
8.702e-03 | -4.74 | calcium-mediated signaling | biological process | GO:0019722 | 154 | 3 | 18204 | 50 |
RYR3,ITPR2,ATP1A2 |
8.712e-03 | -4.74 | ATPase-coupled monoatomic cation transmembrane transporter activity | molecular function | GO:0019829 | 53 | 2 | 18094 | 48 |
ATP1A2,ATP13A4 |
8.713e-03 | -4.74 | Aquaporin-mediated transport | REACTOME pathways | R-HSA-445717 | 52 | 2 | 10285 | 28 |
AQP4,ADCY2 |
8.748e-03 | -4.74 | ZYX (zyxin) | protein interactions | 7791 | 316 | 4 | 19454 | 50 |
NEBL,SORBS1,ABLIM1,MACF1 |
8.771e-03 | -4.74 | EGR2 (early growth response 2) | protein interactions | 1959 | 165 | 3 | 19454 | 50 |
SOX5,NFIA,TRPS1 |
8.771e-03 | -4.74 | positive regulation of nervous system development | biological process | GO:0051962 | 296 | 4 | 18204 | 50 |
PTPRZ1,NTRK2,MACF1,QKI |
8.873e-03 | -4.72 | muscle system process | biological process | GO:0003012 | 297 | 4 | 18204 | 50 |
PRKG1,DTNA,ATP1A2,RYR3 |
8.889e-03 | -4.72 | - | gene3d domains | 1.10.490.160 | 3 | 1 | 14470 | 43 |
RYR3 |
8.889e-03 | -4.72 | - | gene3d domains | 6.10.250.970 | 3 | 1 | 14470 | 43 |
MAML2 |
8.889e-03 | -4.72 | - | gene3d domains | 6.10.250.2510 | 3 | 1 | 14470 | 43 |
CTNNA2 |
8.917e-03 | -4.72 | SCLT1 (sodium channel and clathrin linker 1) | protein interactions | 132320 | 166 | 3 | 19454 | 50 |
ABLIM1,NEBL,ATP1A2 |
9.053e-03 | -4.70 | CTNNB1 (catenin beta 1) | protein interactions | 1499 | 926 | 7 | 19454 | 50 |
CTNNA2,CTNND2,SORBS1,PTPRZ1,NHSL1,DTNA,PARD3B |
9.087e-03 | -4.70 | metal ion binding | molecular function | GO:0046872 | 4239 | 19 | 18094 | 48 |
SPARCL1,ADCY2,ZBTB20,ATP13A4,MACF1,ATP1A2,DTNA,RYR3,TRPS1,ABLIM1,ITPR2,BMPR1B,SLC1A3,CSGALNACT1,GLIS3,RORA,PCDH9,SLC1A2,MGAT4C |
9.125e-03 | -4.70 | SEPTIN3 (septin 3) | protein interactions | 55964 | 56 | 2 | 19454 | 50 |
GPM6A,PRKG1 |
9.156e-03 | -4.69 | ear | COSMIC cancer mutations | ear | 624 | 6 | 16828 | 49 |
LIFR,ZBTB20,PRKG1,NPAS3,MGAT4C,SPARCL1 |
9.206e-03 | -4.69 | rhabdomyosarcoma | COSMIC cancer mutations | rhabdomyosarcoma | 4150 | 20 | 16828 | 49 |
NFIA,PARD3B,SPARCL1,GLIS3,CDH20,PPP2R2B,AQP4,MAML2,ADCY2,NHSL1,RYR3,MACF1,TRPS1,RORA,CTNND2,NPAS3,PTPRZ1,SORBS1,SASH1,SLC1A3 |
9.212e-03 | -4.69 | POU2F1 (POU class 2 homeobox 1) | protein interactions | 5451 | 168 | 3 | 19454 | 50 |
LIFR,GPC5,SOX5 |
9.212e-03 | -4.69 | PPL (periplakin) | protein interactions | 5493 | 168 | 3 | 19454 | 50 |
ITPR2,NKAIN3,PPP2R2B |
9.268e-03 | -4.68 | Adrenergic signaling in cardiomyocytes | KEGG pathways | ko04261 | 144 | 3 | 7161 | 22 |
ADCY2,ATP1A2,PPP2R2B |
9.268e-03 | -4.68 | Adrenergic signaling in cardiomyocytes | KEGG pathways | hsa04261 | 144 | 3 | 7161 | 22 |
ADCY2,PPP2R2B,ATP1A2 |
9.318e-03 | -4.68 | neutral amino acid transport | biological process | GO:0015804 | 53 | 2 | 18204 | 50 |
SLC1A2,SLC1A3 |
9.346e-03 | -4.67 | LRRNT | interpro domains | IPR000372 | 54 | 2 | 18521 | 50 |
LRIG1,NTRK2 |
9.428e-03 | -4.66 | upper_aerodigestive_tract-pharynx-carcinoma-squamous_cell_carcinoma | COSMIC cancer mutations | upper_aerodigestive_tract-pharynx-carcinoma-squamous_cell_carcinoma | 1485 | 10 | 16828 | 49 |
DTNA,SORBS1,NPAS3,PTPRZ1,PCDH9,NRG3,GPC5,PARD3B,MACF1,RYR3 |
9.442e-03 | -4.66 | TREX2 (three prime repair exonuclease 2) | protein interactions | 11219 | 57 | 2 | 19454 | 50 |
PPP2R2B,PARD3B |
9.463e-03 | -4.66 | binding | molecular function | GO:0005488 | 16422 | 48 | 18094 | 48 |
GPM6A,GPC5,SOX5,CSGALNACT1,GLIS3,ABLIM1,PTPRZ1,SASH1,LRIG1,SORBS1,LSAMP,ZBTB20,ATP13A4,PCDH9,CTNND2,RFX4,SLC1A3,NTM,TRPS1,PITPNC1,ATP1A2,RYR3,PARD3B,ADCY2,RORA,PPP2R2B,MAML2,MGAT4C,LIFR,NPAS3,NTRK2,CDH20,NEBL,MACF1,AQP4,CTNNA2,QKI,PRKG1,SLC1A2,DCLK2,ITPR2,FBXL7,BMPR1B,NRG3,MSI2,DTNA,NFIA,SPARCL1 |
9.564e-03 | -4.65 | side of membrane | cellular component | GO:0098552 | 715 | 6 | 19108 | 49 |
GPC5,LIFR,DTNA,LSAMP,NTM,AQP4 |
9.634e-03 | -4.64 | biliary_tract | COSMIC cancer mutations | biliary_tract | 15309 | 49 | 16828 | 49 |
TRPS1,ITPR2,BMPR1B,NPAS3,PCDH9,SLC1A3,LSAMP,FBXL7,LIFR,NFIA,MSI2,NRG3,ABLIM1,NHSL1,DTNA,NEBL,RYR3,CTNND2,PTPRZ1,PITPNC1,NKAIN3,GLIS3,PARD3B,SPARCL1,SLC1A2,NTRK2,LRIG1,ATP1A2,CSGALNACT1,RORA,SOX5,ZBTB20,NTM,SASH1,MGAT4C,GPM6A,PPP2R2B,RFX4,ADCY2,DCLK2,ATP13A4,MACF1,PRKG1,SORBS1,QKI,CDH20,GPC5,AQP4,MAML2 |
9.725e-03 | -4.63 | acinar_carcinoma | COSMIC cancer mutations | acinar_carcinoma | 1978 | 12 | 16828 | 49 |
ZBTB20,CTNND2,SOX5,SASH1,PTPRZ1,NHSL1,CSGALNACT1,LIFR,ATP1A2,BMPR1B,QKI,PARD3B |
9.725e-03 | -4.63 | pancreas-carcinoma-acinar_carcinoma | COSMIC cancer mutations | pancreas-carcinoma-acinar_carcinoma | 1978 | 12 | 16828 | 49 |
NHSL1,QKI,PARD3B,LIFR,PTPRZ1,SASH1,SOX5,ZBTB20,CTNND2,BMPR1B,CSGALNACT1,ATP1A2 |
9.751e-03 | -4.63 | dendritic spine | cellular component | GO:0043197 | 172 | 3 | 19108 | 49 |
NTRK2,ATP1A2,GPM6A |
9.858e-03 | -4.62 | skin-scalp-malignant_melanoma | COSMIC cancer mutations | skin-scalp-malignant_melanoma | 634 | 6 | 16828 | 49 |
NEBL,NFIA,PPP2R2B,NTM,PTPRZ1,SORBS1 |
9.962e-03 | -4.61 | medullary_carcinoma | COSMIC cancer mutations | medullary_carcinoma | 290 | 4 | 16828 | 49 |
PARD3B,PRKG1,SLC1A2,NRG3 |
9.962e-03 | -4.61 | thyroid-carcinoma-medullary_carcinoma | COSMIC cancer mutations | thyroid-carcinoma-medullary_carcinoma | 290 | 4 | 16828 | 49 |
NRG3,PARD3B,PRKG1,SLC1A2 |
1.001e-02 | -4.60 | response to cocaine | biological process | GO:0042220 | 55 | 2 | 18204 | 50 |
SLC1A2,SLC1A3 |
1.002e-02 | -4.60 | Znf_NHR/GATA | interpro domains | IPR013088 | 56 | 2 | 18521 | 50 |
TRPS1,RORA |
1.006e-02 | -4.60 | neuron spine | cellular component | GO:0044309 | 174 | 3 | 19108 | 49 |
NTRK2,ATP1A2,GPM6A |
1.013e-02 | -4.59 | DUSP14 (dual specificity phosphatase 14) | protein interactions | 11072 | 174 | 3 | 19454 | 50 |
CSGALNACT1,SPARCL1,QKI |
1.022e-02 | -4.58 | extrinsic component of membrane | cellular component | GO:0019898 | 175 | 3 | 19108 | 49 |
DTNA,CDH20,CTNNA2 |
1.024e-02 | -4.58 | Ilkap (integrin-linked kinase-associated serine/threonine phosphatase 2C) | protein interactions | 67444 | 4 | 1 | 19454 | 50 |
BMPR1B |
1.024e-02 | -4.58 | Srgap1 (SLIT-ROBO Rho GTPase activating protein 1) | protein interactions | 117600 | 4 | 1 | 19454 | 50 |
BMPR1B |
1.024e-02 | -4.58 | Rhebl1 (Ras homolog enriched in brain like 1) | protein interactions | 69159 | 4 | 1 | 19454 | 50 |
BMPR1B |
1.024e-02 | -4.58 | IER5L (immediate early response 5 like) | protein interactions | 389792 | 4 | 1 | 19454 | 50 |
PPP2R2B |
1.024e-02 | -4.58 | CCDC126 (coiled-coil domain containing 126) | protein interactions | 90693 | 4 | 1 | 19454 | 50 |
GPM6A |
1.024e-02 | -4.58 | Naa20 (N(alpha)-acetyltransferase 20, NatB catalytic subunit) | protein interactions | 67877 | 4 | 1 | 19454 | 50 |
BMPR1B |
1.024e-02 | -4.58 | Cdk14 (cyclin dependent kinase 14) | protein interactions | 18647 | 4 | 1 | 19454 | 50 |
BMPR1B |
1.024e-02 | -4.58 | Dnaja1 (DnaJ heat shock protein family (Hsp40) member A1) | protein interactions | 15502 | 4 | 1 | 19454 | 50 |
GLIS3 |
1.024e-02 | -4.58 | Nkiras1 (NFKB inhibitor interacting Ras-like protein 1) | protein interactions | 69721 | 4 | 1 | 19454 | 50 |
BMPR1B |
1.024e-02 | -4.58 | Nme2 (NME/NM23 nucleoside diphosphate kinase 2) | protein interactions | 18103 | 4 | 1 | 19454 | 50 |
RORA |
1.024e-02 | -4.58 | Ctbp2 (C-terminal binding protein 2) | protein interactions | 13017 | 4 | 1 | 19454 | 50 |
TRPS1 |
1.024e-02 | -4.58 | Arhgef6 (Rac/Cdc42 guanine nucleotide exchange factor 6) | protein interactions | 73341 | 4 | 1 | 19454 | 50 |
BMPR1B |
1.029e-02 | -4.58 | LHX3 (LIM homeobox 3) | protein interactions | 8022 | 175 | 3 | 19454 | 50 |
SOX5,NFIA,TRPS1 |
1.036e-02 | -4.57 | release of sequestered calcium ion into cytosol | biological process | GO:0051209 | 56 | 2 | 18204 | 50 |
RYR3,ITPR2 |
1.043e-02 | -4.56 | actin cytoskeleton | cellular component | GO:0015629 | 520 | 5 | 19108 | 49 |
SORBS1,CTNNA2,MACF1,ABLIM1,NEBL |
1.049e-02 | -4.56 | import across plasma membrane | biological process | GO:0098739 | 165 | 3 | 18204 | 50 |
SLC1A3,SLC1A2,ATP1A2 |
1.055e-02 | -4.55 | SOHO | prosite domains | PS50831 | 3 | 1 | 12186 | 43 |
SORBS1 |
1.055e-02 | -4.55 | MYELIN_PLP_1 | prosite domains | PS00575 | 3 | 1 | 12186 | 43 |
GPM6A |
1.055e-02 | -4.55 | MYELIN_PLP_2 | prosite domains | PS01004 | 3 | 1 | 12186 | 43 |
GPM6A |
1.055e-02 | -4.55 | VINCULIN_1 | prosite domains | PS00663 | 3 | 1 | 12186 | 43 |
CTNNA2 |
1.057e-02 | -4.55 | ryanodine-sensitive calcium-release channel activity | molecular function | GO:0005219 | 4 | 1 | 18094 | 48 |
RYR3 |
1.057e-02 | -4.55 | ciliary neurotrophic factor receptor activity | molecular function | GO:0004897 | 4 | 1 | 18094 | 48 |
LIFR |
1.057e-02 | -4.55 | brain-derived neurotrophic factor binding | molecular function | GO:0048403 | 4 | 1 | 18094 | 48 |
NTRK2 |
1.061e-02 | -4.55 | GATA3 (GATA binding protein 3) | protein interactions | 2625 | 177 | 3 | 19454 | 50 |
QKI,TRPS1,NFIA |
1.061e-02 | -4.55 | adrenal_cortical_carcinoma | COSMIC cancer mutations | adrenal_cortical_carcinoma | 2256 | 13 | 16828 | 49 |
SOX5,CTNND2,ZBTB20,PTPRZ1,PCDH9,ATP1A2,LRIG1,MAML2,RFX4,NRG3,NTRK2,NHSL1,SLC1A2 |
1.065e-02 | -4.54 | ovary-other-neoplasm | COSMIC cancer mutations | ovary-other-neoplasm | 12717 | 44 | 16828 | 49 |
ATP13A4,MACF1,PRKG1,SORBS1,CDH20,QKI,GPC5,AQP4,MAML2,LRIG1,ATP1A2,CSGALNACT1,RORA,SOX5,ZBTB20,NTM,SASH1,MGAT4C,PPP2R2B,GPM6A,RFX4,DCLK2,ADCY2,NEBL,RYR3,CTNND2,NKAIN3,PARD3B,GLIS3,SPARCL1,SLC1A2,NTRK2,TRPS1,ITPR2,BMPR1B,PCDH9,LSAMP,SLC1A3,FBXL7,LIFR,MSI2,NRG3,ABLIM1,NHSL1 |
1.072e-02 | -4.54 | visual behavior | biological process | GO:0007632 | 57 | 2 | 18204 | 50 |
SLC1A2,ATP1A2 |
1.072e-02 | -4.54 | negative regulation of sequestering of calcium ion | biological process | GO:0051283 | 57 | 2 | 18204 | 50 |
RYR3,ITPR2 |
1.074e-02 | -4.53 | Oxytocin signaling pathway | KEGG pathways | hsa04921 | 152 | 3 | 7161 | 22 |
RYR3,ITPR2,ADCY2 |
1.074e-02 | -4.53 | Oxytocin signaling pathway | KEGG pathways | ko04921 | 152 | 3 | 7161 | 22 |
RYR3,ITPR2,ADCY2 |
1.075e-02 | -4.53 | NfI_DNAbd_pre-N | pfam domains | PF10524 | 4 | 1 | 17795 | 48 |
NFIA |
1.075e-02 | -4.53 | Spectrin_3 | pfam domains | PF21019 | 4 | 1 | 17795 | 48 |
MACF1 |
1.075e-02 | -4.53 | P5-ATPase | pfam domains | PF12409 | 4 | 1 | 17795 | 48 |
ATP13A4 |
1.075e-02 | -4.53 | CTF_NFI | pfam domains | PF00859 | 4 | 1 | 17795 | 48 |
NFIA |
1.075e-02 | -4.53 | Nebulin | pfam domains | PF00880 | 4 | 1 | 17795 | 48 |
NEBL |
1.075e-02 | -4.53 | NHS | pfam domains | PF15273 | 4 | 1 | 17795 | 48 |
NHSL1 |
1.075e-02 | -4.53 | NKAIN | pfam domains | PF05640 | 4 | 1 | 17795 | 48 |
NKAIN3 |
1.075e-02 | -4.53 | Spectrin_4 | pfam domains | PF21020 | 4 | 1 | 17795 | 48 |
MACF1 |
1.075e-02 | -4.53 | AbLIM_anchor | pfam domains | PF16182 | 4 | 1 | 17795 | 48 |
ABLIM1 |
1.075e-02 | -4.53 | Spectrin_2 | pfam domains | PF18373 | 4 | 1 | 17795 | 48 |
MACF1 |
1.075e-02 | -4.53 | Glyco_transf_54 | pfam domains | PF04666 | 4 | 1 | 17795 | 48 |
MGAT4C |
1.075e-02 | -4.53 | Ion transport by P-type ATPases | REACTOME pathways | R-HSA-936837 | 58 | 2 | 10285 | 28 |
ATP13A4,ATP1A2 |
1.076e-02 | -4.53 | Nebulin_repeat | interpro domains | IPR000900 | 4 | 1 | 18521 | 50 |
NEBL |
1.076e-02 | -4.53 | CTF/NFI_DNA-bd-dom | interpro domains | IPR020604 | 4 | 1 | 18521 | 50 |
NFIA |
1.076e-02 | -4.53 | Alpha_catenin | interpro domains | IPR001033 | 4 | 1 | 18521 | 50 |
CTNNA2 |
1.076e-02 | -4.53 | P5A-ATPase_N | interpro domains | IPR047819 | 4 | 1 | 18521 | 50 |
ATP13A4 |
1.076e-02 | -4.53 | AbLIM_anchor | interpro domains | IPR032402 | 4 | 1 | 18521 | 50 |
ABLIM1 |
1.076e-02 | -4.53 | CTF/NFI | interpro domains | IPR000647 | 4 | 1 | 18521 | 50 |
NFIA |
1.076e-02 | -4.53 | PP2A_PR55 | interpro domains | IPR000009 | 4 | 1 | 18521 | 50 |
PPP2R2B |
1.076e-02 | -4.53 | CTF/NFI_DNA-bd_CS | interpro domains | IPR019739 | 4 | 1 | 18521 | 50 |
NFIA |
1.076e-02 | -4.53 | P5B-type_ATPase | interpro domains | IPR047821 | 4 | 1 | 18521 | 50 |
ATP13A4 |
1.076e-02 | -4.53 | Na/K-Atpase_Interacting | interpro domains | IPR008516 | 4 | 1 | 18521 | 50 |
NKAIN3 |
1.076e-02 | -4.53 | Desmoplakin_Spectrin-like | interpro domains | IPR041573 | 4 | 1 | 18521 | 50 |
MACF1 |
1.076e-02 | -4.53 | PP2A_PR55_CS | interpro domains | IPR018067 | 4 | 1 | 18521 | 50 |
PPP2R2B |
1.076e-02 | -4.53 | PCN-like_spectrin-like_rpt | interpro domains | IPR049538 | 4 | 1 | 18521 | 50 |
MACF1 |
1.076e-02 | -4.53 | Glyco_transf_54 | interpro domains | IPR006759 | 4 | 1 | 18521 | 50 |
MGAT4C |
1.076e-02 | -4.53 | NHS-like | interpro domains | IPR024845 | 4 | 1 | 18521 | 50 |
NHSL1 |
1.076e-02 | -4.53 | CTF/NFI_DNA-bd_N | interpro domains | IPR019548 | 4 | 1 | 18521 | 50 |
NFIA |
1.077e-02 | -4.53 | ERBB4 (erb-b2 receptor tyrosine kinase 4) | protein interactions | 2066 | 178 | 3 | 19454 | 50 |
LRIG1,NRG3,NTRK2 |
1.094e-02 | -4.52 | leukemia inhibitory factor signaling pathway | biological process | GO:0048861 | 4 | 1 | 18204 | 50 |
LIFR |
1.094e-02 | -4.52 | brain-derived neurotrophic factor receptor signaling pathway | biological process | GO:0031547 | 4 | 1 | 18204 | 50 |
NTRK2 |
1.094e-02 | -4.52 | response to glycoside | biological process | GO:1903416 | 4 | 1 | 18204 | 50 |
ATP1A2 |
1.094e-02 | -4.52 | oncostatin-M-mediated signaling pathway | biological process | GO:0038165 | 4 | 1 | 18204 | 50 |
LIFR |
1.094e-02 | -4.52 | regulation of amino acid uptake involved in synaptic transmission | biological process | GO:0051941 | 4 | 1 | 18204 | 50 |
ATP1A2 |
1.094e-02 | -4.52 | ovarian cumulus expansion | biological process | GO:0001550 | 4 | 1 | 18204 | 50 |
BMPR1B |
1.094e-02 | -4.52 | positive regulation of mesenchymal stem cell differentiation | biological process | GO:2000741 | 4 | 1 | 18204 | 50 |
SOX5 |
1.094e-02 | -4.52 | regulation of glutamate uptake involved in transmission of nerve impulse | biological process | GO:0051946 | 4 | 1 | 18204 | 50 |
ATP1A2 |
1.094e-02 | -4.52 | trans-synaptic signaling by BDNF | biological process | GO:0099191 | 4 | 1 | 18204 | 50 |
NTRK2 |
1.096e-02 | -4.51 | lung-carcinoma-large_cell_carcinoma | COSMIC cancer mutations | lung-carcinoma-large_cell_carcinoma | 849 | 7 | 16828 | 49 |
NTRK2,DCLK2,PTPRZ1,LRIG1,LIFR,BMPR1B,PRKG1 |
1.096e-02 | -4.51 | large_cell_carcinoma | COSMIC cancer mutations | large_cell_carcinoma | 849 | 7 | 16828 | 49 |
BMPR1B,PRKG1,DCLK2,PTPRZ1,LIFR,NTRK2,LRIG1 |
1.098e-02 | -4.51 | primitive_neuroectodermal_tumour-medulloblastoma | COSMIC cancer mutations | primitive_neuroectodermal_tumour-medulloblastoma | 15350 | 49 | 16828 | 49 |
CTNND2,PTPRZ1,NEBL,RYR3,NTRK2,NKAIN3,PITPNC1,SLC1A2,GLIS3,PARD3B,SPARCL1,LSAMP,SLC1A3,PCDH9,NPAS3,TRPS1,BMPR1B,ITPR2,NRG3,ABLIM1,DTNA,NHSL1,FBXL7,NFIA,LIFR,MSI2,SORBS1,MACF1,ATP13A4,PRKG1,AQP4,MAML2,GPC5,CDH20,QKI,ZBTB20,SOX5,RORA,SASH1,NTM,ATP1A2,CSGALNACT1,LRIG1,RFX4,PPP2R2B,GPM6A,ADCY2,DCLK2,MGAT4C |
1.104e-02 | -4.51 | EZR (ezrin) | protein interactions | 7430 | 526 | 5 | 19454 | 50 |
MACF1,DTNA,SORBS1,ABLIM1,NEBL |
1.106e-02 | -4.50 | chondroitin biosynthesis | BIOCYC pathways | META_PWY-6566 | 5 | 1 | 902 | 2 |
CSGALNACT1 |
1.110e-02 | -4.50 | ZKSCAN1 (zinc finger with KRAB and SCAN domains 1) | protein interactions | 7586 | 62 | 2 | 19454 | 50 |
PRKG1,QKI |
1.110e-02 | -4.50 | cellular homeostasis | biological process | GO:0019725 | 689 | 6 | 18204 | 50 |
ATP13A4,AQP4,SLC1A3,RYR3,ZBTB20,ATP1A2 |
1.110e-02 | -4.50 | MYOD1 (myogenic differentiation 1) | protein interactions | 4654 | 180 | 3 | 19454 | 50 |
NFIA,TRPS1,RORA |
1.113e-02 | -4.50 | Hippo signaling pathway | KEGG pathways | ko04390 | 154 | 3 | 7161 | 22 |
BMPR1B,CTNNA2,PPP2R2B |
1.113e-02 | -4.50 | Hippo signaling pathway | KEGG pathways | hsa04390 | 154 | 3 | 7161 | 22 |
PPP2R2B,CTNNA2,BMPR1B |
1.138e-02 | -4.48 | striated_muscle | COSMIC cancer mutations | striated_muscle | 4228 | 20 | 16828 | 49 |
NFIA,CDH20,GLIS3,PARD3B,SPARCL1,PPP2R2B,MAML2,AQP4,NHSL1,ADCY2,RYR3,MACF1,TRPS1,RORA,CTNND2,NPAS3,PTPRZ1,SLC1A3,SASH1,SORBS1 |
1.138e-02 | -4.48 | head_neck | COSMIC cancer mutations | head_neck | 15361 | 49 | 16828 | 49 |
DTNA,NHSL1,NRG3,ABLIM1,MSI2,FBXL7,LIFR,NFIA,SLC1A3,LSAMP,NPAS3,PCDH9,BMPR1B,ITPR2,TRPS1,NTRK2,SLC1A2,SPARCL1,PARD3B,GLIS3,NKAIN3,PITPNC1,PTPRZ1,CTNND2,NEBL,RYR3,DCLK2,ADCY2,RFX4,PPP2R2B,GPM6A,MGAT4C,SASH1,NTM,ZBTB20,SOX5,RORA,ATP1A2,CSGALNACT1,LRIG1,AQP4,MAML2,GPC5,QKI,CDH20,SORBS1,PRKG1,MACF1,ATP13A4 |
1.140e-02 | -4.47 | neuron projection development | biological process | GO:0031175 | 693 | 6 | 18204 | 50 |
CTNND2,GPM6A,BMPR1B,PRKG1,PTPRZ1,CTNNA2 |
1.143e-02 | -4.47 | human chr4q34.2 | chromosome location | human chr4q34.2 | 6 | 1 | 26134 | 50 |
GPM6A |
1.143e-02 | -4.47 | human chr14q13.1 | chromosome location | human chr14q13.1 | 6 | 1 | 26134 | 50 |
NPAS3 |
1.144e-02 | -4.47 | PRPH (peripherin) | protein interactions | 5630 | 182 | 3 | 19454 | 50 |
PPP2R2B,SORBS1,ABLIM1 |
1.145e-02 | -4.47 | endochondral bone morphogenesis | biological process | GO:0060350 | 59 | 2 | 18204 | 50 |
CSGALNACT1,BMPR1B |
1.145e-02 | -4.47 | YWHAG (tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein gamma) | protein interactions | 7532 | 1211 | 8 | 19454 | 50 |
PARD3B,PITPNC1,NHSL1,SASH1,ABLIM1,SORBS1,MACF1,DCLK2 |
1.148e-02 | -4.47 | Signaling by BRAF and RAF fusions | REACTOME pathways | R-HSA-6802952 | 60 | 2 | 10285 | 28 |
MACF1,QKI |
1.156e-02 | -4.46 | oligodendroglioma_Grade_III | COSMIC cancer mutations | oligodendroglioma_Grade_III | 303 | 4 | 16828 | 49 |
MACF1,MGAT4C,GLIS3,PTPRZ1 |
1.167e-02 | -4.45 | haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-peripheral_T_cell_lymphoma_unspecified | COSMIC cancer mutations | haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-peripheral_T_cell_lymphoma_unspecified | 162 | 3 | 16828 | 49 |
ITPR2,RYR3,MACF1 |
1.169e-02 | -4.45 | Sorb | smart domains | SM00459 | 3 | 1 | 9717 | 38 |
SORBS1 |
1.169e-02 | -4.45 | PLP | smart domains | SM00002 | 3 | 1 | 9717 | 38 |
GPM6A |
1.169e-02 | -4.45 | MamL-1 | smart domains | SM01275 | 3 | 1 | 9717 | 38 |
MAML2 |
1.171e-02 | -4.45 | Regulation of lipolysis in adipocytes | KEGG pathways | hsa04923 | 54 | 2 | 7161 | 22 |
ADCY2,PRKG1 |
1.175e-02 | -4.44 | skeletal system development | biological process | GO:0001501 | 500 | 5 | 18204 | 50 |
BMPR1B,SOX5,CSGALNACT1,TRPS1,NFIA |
1.178e-02 | -4.44 | cation binding | molecular function | GO:0043169 | 4341 | 19 | 18094 | 48 |
RYR3,ATP1A2,DTNA,ADCY2,SPARCL1,MACF1,ATP13A4,ZBTB20,GLIS3,SLC1A3,CSGALNACT1,SLC1A2,MGAT4C,RORA,PCDH9,TRPS1,BMPR1B,ITPR2,ABLIM1 |
1.178e-02 | -4.44 | SH3_2 | pfam domains | PF07653 | 61 | 2 | 17795 | 48 |
SASH1,SORBS1 |
1.179e-02 | -4.44 | SYNC (syncoilin, intermediate filament protein) | protein interactions | 81493 | 64 | 2 | 19454 | 50 |
DTNA,MAML2 |
1.179e-02 | -4.44 | EVA1C (eva-1 homolog C) | protein interactions | 59271 | 64 | 2 | 19454 | 50 |
PCDH9,BMPR1B |
1.179e-02 | -4.44 | VSX1 (visual system homeobox 1) | protein interactions | 30813 | 64 | 2 | 19454 | 50 |
NFIA,TRPS1 |
1.182e-02 | -4.44 | protein homotetramerization | biological process | GO:0051289 | 60 | 2 | 18204 | 50 |
AQP4,RYR3 |
1.182e-02 | -4.44 | proteoglycan biosynthetic process | biological process | GO:0030166 | 60 | 2 | 18204 | 50 |
BMPR1B,CSGALNACT1 |
1.182e-02 | -4.44 | regulation of smooth muscle contraction | biological process | GO:0006940 | 60 | 2 | 18204 | 50 |
PRKG1,ATP1A2 |
1.182e-02 | -4.44 | transmission of nerve impulse | biological process | GO:0019226 | 60 | 2 | 18204 | 50 |
ATP1A2,NTRK2 |
1.182e-02 | -4.44 | regulation of glucose import | biological process | GO:0046324 | 60 | 2 | 18204 | 50 |
SORBS1,SLC1A2 |
1.184e-02 | -4.44 | - | gene3d domains | 1.20.58.1060 | 4 | 1 | 14470 | 43 |
MACF1 |
1.184e-02 | -4.44 | cadherin binding | molecular function | GO:0045296 | 335 | 4 | 18094 | 48 |
CTNNA2,MACF1,CTNND2,CDH20 |
1.185e-02 | -4.44 | Ca2+ pathway | REACTOME pathways | R-HSA-4086398 | 61 | 2 | 10285 | 28 |
PRKG1,ITPR2 |
1.190e-02 | -4.43 | biliary_tract-gallbladder-carcinoma-adenocarcinoma | COSMIC cancer mutations | biliary_tract-gallbladder-carcinoma-adenocarcinoma | 2821 | 15 | 16828 | 49 |
PITPNC1,NKAIN3,SPARCL1,NRG3,NHSL1,LRIG1,RYR3,MACF1,TRPS1,ITPR2,PRKG1,CTNND2,PCDH9,PTPRZ1,SASH1 |
1.190e-02 | -4.43 | gallbladder | COSMIC cancer mutations | gallbladder | 2821 | 15 | 16828 | 49 |
NRG3,NHSL1,NKAIN3,PITPNC1,SPARCL1,CTNND2,SASH1,PTPRZ1,PCDH9,MACF1,TRPS1,LRIG1,RYR3,PRKG1,ITPR2 |
1.192e-02 | -4.43 | chemical homeostasis | biological process | GO:0048878 | 914 | 7 | 18204 | 50 |
RORA,ATP13A4,RYR3,AQP4,SLC1A3,ATP1A2,ZBTB20 |
1.200e-02 | -4.42 | Erythroid Transcription Factor GATA-1, subunit A | gene3d domains | 3.30.50.10 | 56 | 2 | 14470 | 43 |
RORA,TRPS1 |
1.201e-02 | -4.42 | RYANODINER | prints domains | PR00795 | 3 | 1 | 5227 | 21 |
RYR3 |
1.201e-02 | -4.42 | NTKRECEPTOR | prints domains | PR01939 | 3 | 1 | 5227 | 21 |
NTRK2 |
1.201e-02 | -4.42 | MYELINPLP | prints domains | PR00214 | 3 | 1 | 5227 | 21 |
GPM6A |
1.201e-02 | -4.42 | RORNUCRECPTR | prints domains | PR01293 | 3 | 1 | 5227 | 21 |
RORA |
1.201e-02 | -4.42 | INSP3RECEPTR | prints domains | PR00779 | 3 | 1 | 5227 | 21 |
ITPR2 |
1.209e-02 | -4.42 | kidney | COSMIC cancer mutations | kidney | 15380 | 49 | 16828 | 49 |
MGAT4C,RFX4,GPM6A,PPP2R2B,DCLK2,ADCY2,ATP1A2,CSGALNACT1,LRIG1,ZBTB20,SOX5,RORA,SASH1,NTM,GPC5,QKI,CDH20,AQP4,MAML2,MACF1,ATP13A4,PRKG1,SORBS1,FBXL7,NFIA,LIFR,MSI2,NRG3,ABLIM1,DTNA,NHSL1,TRPS1,BMPR1B,ITPR2,LSAMP,SLC1A3,NPAS3,PCDH9,PITPNC1,NKAIN3,SLC1A2,PARD3B,GLIS3,SPARCL1,NTRK2,NEBL,RYR3,CTNND2,PTPRZ1 |
1.223e-02 | -4.40 | cellular response to organonitrogen compound | biological process | GO:0071417 | 505 | 5 | 18204 | 50 |
SLC1A3,SLC1A2,RYR3,ITPR2,SORBS1 |
1.228e-02 | -4.40 | ovary-carcinoma-clear_cell_carcinoma | COSMIC cancer mutations | ovary-carcinoma-clear_cell_carcinoma | 665 | 6 | 16828 | 49 |
NTRK2,LIFR,SPARCL1,DCLK2,BMPR1B,PRKG1 |
1.230e-02 | -4.40 | regulation of lipid metabolic process | biological process | GO:0019216 | 327 | 4 | 18204 | 50 |
PRKG1,RORA,SORBS1,ZBTB20 |
1.240e-02 | -4.39 | cell migration | biological process | GO:0016477 | 921 | 7 | 18204 | 50 |
NTRK2,GPM6A,NRG3,PRKG1,CTNNA2,CDH20,GPC5 |
1.248e-02 | -4.38 | HNF1B (HNF1 homeobox B) | protein interactions | 6928 | 188 | 3 | 19454 | 50 |
SOX5,TRPS1,NFIA |
1.250e-02 | -4.38 | MAML1 (mastermind like transcriptional coactivator 1) | protein interactions | 9794 | 66 | 2 | 19454 | 50 |
NFIA,MAML2 |
1.253e-02 | -4.38 | SH3_9 | pfam domains | PF14604 | 63 | 2 | 17795 | 48 |
NEBL,SORBS1 |
1.256e-02 | -4.38 | plasma membrane bounded cell projection organization | biological process | GO:0120036 | 1152 | 8 | 18204 | 50 |
BMPR1B,RFX4,PRKG1,CTNND2,ABLIM1,GPM6A,PTPRZ1,CTNNA2 |
1.262e-02 | -4.37 | clear_cell_carcinoma | COSMIC cancer mutations | clear_cell_carcinoma | 669 | 6 | 16828 | 49 |
LIFR,NTRK2,BMPR1B,PRKG1,SPARCL1,DCLK2 |
1.262e-02 | -4.37 | Ig-like_fold | interpro domains | IPR013783 | 721 | 6 | 18521 | 50 |
LSAMP,LRIG1,NTM,PTPRZ1,NTRK2,LIFR |
1.266e-02 | -4.37 | peripheral_T_cell_lymphoma_unspecified | COSMIC cancer mutations | peripheral_T_cell_lymphoma_unspecified | 167 | 3 | 16828 | 49 |
ITPR2,MACF1,RYR3 |
1.279e-02 | -4.36 | Rab38 (RAB38, member RAS oncogene family) | protein interactions | 72433 | 5 | 1 | 19454 | 50 |
BMPR1B |
1.279e-02 | -4.36 | Rras2 (related RAS viral (r-ras) oncogene 2) | protein interactions | 66922 | 5 | 1 | 19454 | 50 |
BMPR1B |
1.279e-02 | -4.36 | PPP1R17 (protein phosphatase 1 regulatory subunit 17) | protein interactions | 10842 | 5 | 1 | 19454 | 50 |
PRKG1 |
1.279e-02 | -4.36 | SLC10A3 (solute carrier family 10 member 3) | protein interactions | 8273 | 5 | 1 | 19454 | 50 |
SORBS1 |
1.279e-02 | -4.36 | Cdk4 (cyclin dependent kinase 4) | protein interactions | 12567 | 5 | 1 | 19454 | 50 |
BMPR1B |
1.279e-02 | -4.36 | Rhobtb1 (Rho-related BTB domain containing 1) | protein interactions | 69288 | 5 | 1 | 19454 | 50 |
BMPR1B |
1.279e-02 | -4.36 | Wwp2 (WW domain containing E3 ubiquitin protein ligase 2) | protein interactions | 66894 | 5 | 1 | 19454 | 50 |
GLIS3 |
1.279e-02 | -4.36 | RFX4 (regulatory factor X4) | protein interactions | 5992 | 5 | 1 | 19454 | 50 |
RFX4 |
1.279e-02 | -4.36 | Rab6b (RAB6B, member RAS oncogene family) | protein interactions | 270192 | 5 | 1 | 19454 | 50 |
BMPR1B |
1.279e-02 | -4.36 | Rhoj (ras homolog family member J) | protein interactions | 80837 | 5 | 1 | 19454 | 50 |
BMPR1B |
1.282e-02 | -4.36 | regulation of small molecule metabolic process | biological process | GO:0062012 | 331 | 4 | 18204 | 50 |
PRKG1,RORA,ZBTB20,SORBS1 |
1.302e-02 | -4.34 | pancreas-carcinoma | COSMIC cancer mutations | pancreas-carcinoma | 14770 | 48 | 16828 | 49 |
MSI2,FBXL7,LIFR,NFIA,NHSL1,NRG3,ABLIM1,BMPR1B,ITPR2,TRPS1,LSAMP,SLC1A3,NPAS3,PCDH9,SLC1A2,SPARCL1,PARD3B,GLIS3,NKAIN3,PITPNC1,NTRK2,NEBL,RYR3,PTPRZ1,CTNND2,MGAT4C,DCLK2,ADCY2,RFX4,GPM6A,PPP2R2B,ATP1A2,CSGALNACT1,LRIG1,SASH1,NTM,ZBTB20,SOX5,RORA,GPC5,QKI,CDH20,AQP4,MAML2,PRKG1,MACF1,ATP13A4,SORBS1 |
1.320e-02 | -4.33 | transforming growth factor beta receptor activity, type I | molecular function | GO:0005025 | 5 | 1 | 18094 | 48 |
BMPR1B |
1.320e-02 | -4.33 | neurotrophin receptor activity | molecular function | GO:0005030 | 5 | 1 | 18094 | 48 |
NTRK2 |
1.327e-02 | -4.32 | L-amino acid transmembrane transporter activity | molecular function | GO:0015179 | 66 | 2 | 18094 | 48 |
SLC1A2,SLC1A3 |
1.332e-02 | -4.32 | testis-germ_cell_tumour-non_seminoma | COSMIC cancer mutations | testis-germ_cell_tumour-non_seminoma | 487 | 5 | 16828 | 49 |
DCLK2,PRKG1,BMPR1B,NTRK2,MACF1 |
1.332e-02 | -4.32 | human chr13q21.32 | chromosome location | human chr13q21.32 | 7 | 1 | 26134 | 50 |
PCDH9 |
1.335e-02 | -4.32 | camera-type eye development | biological process | GO:0043010 | 335 | 4 | 18204 | 50 |
BMPR1B,NTRK2,GPM6A,NFIA |
1.337e-02 | -4.31 | dendrite morphogenesis | biological process | GO:0048813 | 64 | 2 | 18204 | 50 |
CTNND2,CTNNA2 |
1.339e-02 | -4.31 | POF1B (POF1B actin binding protein) | protein interactions | 79983 | 193 | 3 | 19454 | 50 |
CSGALNACT1,PPP2R2B,NKAIN3 |
1.342e-02 | -4.31 | Vinculin | pfam domains | PF01044 | 5 | 1 | 17795 | 48 |
CTNNA2 |
1.342e-02 | -4.31 | FOLN | pfam domains | PF09289 | 5 | 1 | 17795 | 48 |
SPARCL1 |
1.342e-02 | -4.31 | IP_trans | pfam domains | PF02121 | 5 | 1 | 17795 | 48 |
PITPNC1 |
1.342e-02 | -4.31 | Protocadherin | pfam domains | PF08374 | 5 | 1 | 17795 | 48 |
PCDH9 |
1.342e-02 | -4.31 | salivary_gland-carcinoma-adenoid_cystic_carcinoma | COSMIC cancer mutations | salivary_gland-carcinoma-adenoid_cystic_carcinoma | 488 | 5 | 16828 | 49 |
RYR3,RORA,CTNND2,MGAT4C,PRKG1 |
1.343e-02 | -4.31 | PI_transfer | interpro domains | IPR001666 | 5 | 1 | 18521 | 50 |
PITPNC1 |
1.343e-02 | -4.31 | Protocadherin | interpro domains | IPR013585 | 5 | 1 | 18521 | 50 |
PCDH9 |
1.343e-02 | -4.31 | BBP-like | interpro domains | IPR045071 | 5 | 1 | 18521 | 50 |
QKI |
1.343e-02 | -4.31 | Follistatin/Osteonectin_EGF | interpro domains | IPR015369 | 5 | 1 | 18521 | 50 |
SPARCL1 |
1.343e-02 | -4.31 | Vinculin/catenin | interpro domains | IPR006077 | 5 | 1 | 18521 | 50 |
CTNNA2 |
1.343e-02 | -4.31 | P-type_TPase_V | interpro domains | IPR006544 | 5 | 1 | 18521 | 50 |
ATP13A4 |
1.352e-02 | -4.30 | NS-malignant_melanoma | COSMIC cancer mutations | NS-malignant_melanoma | 3420 | 17 | 16828 | 49 |
LIFR,PITPNC1,GPC5,GLIS3,MGAT4C,NRG3,RFX4,ADCY2,ATP1A2,MACF1,ATP13A4,NEBL,LRIG1,ITPR2,CTNND2,PTPRZ1,PCDH9 |
1.354e-02 | -4.30 | NGF-independant TRKA activation | REACTOME pathways | R-HSA-187024 | 5 | 1 | 10285 | 28 |
NTRK2 |
1.366e-02 | -4.29 | amygdala development | biological process | GO:0021764 | 5 | 1 | 18204 | 50 |
ATP1A2 |
1.366e-02 | -4.29 | negative regulation of glutamate secretion | biological process | GO:0014050 | 5 | 1 | 18204 | 50 |
PRKG1 |
1.366e-02 | -4.29 | otolith morphogenesis | biological process | GO:0032474 | 5 | 1 | 18204 | 50 |
LRIG1 |
1.366e-02 | -4.29 | negative regulation of chondrocyte proliferation | biological process | GO:1902731 | 5 | 1 | 18204 | 50 |
BMPR1B |
1.366e-02 | -4.29 | ciliary neurotrophic factor-mediated signaling pathway | biological process | GO:0070120 | 5 | 1 | 18204 | 50 |
LIFR |
1.366e-02 | -4.29 | synaptic signaling via neuropeptide | biological process | GO:0099538 | 5 | 1 | 18204 | 50 |
NTRK2 |
1.367e-02 | -4.29 | neoplasm | COSMIC cancer mutations | neoplasm | 14787 | 48 | 16828 | 49 |
BMPR1B,ITPR2,TRPS1,SLC1A3,LSAMP,PCDH9,NPAS3,MSI2,FBXL7,LIFR,NFIA,DTNA,NHSL1,NRG3,ABLIM1,NEBL,RYR3,PTPRZ1,CTNND2,SLC1A2,SPARCL1,GLIS3,PARD3B,NKAIN3,NTRK2,ATP1A2,CSGALNACT1,LRIG1,SASH1,NTM,SOX5,ZBTB20,RORA,MGAT4C,ADCY2,DCLK2,RFX4,PPP2R2B,GPM6A,PRKG1,MACF1,ATP13A4,SORBS1,GPC5,QKI,CDH20,AQP4,MAML2 |
1.368e-02 | -4.29 | IGc2 | smart domains | SM00408 | 239 | 4 | 9717 | 38 |
NTM,NTRK2,LSAMP,LRIG1 |
1.387e-02 | -4.28 | non_seminoma | COSMIC cancer mutations | non_seminoma | 492 | 5 | 16828 | 49 |
NTRK2,MACF1,DCLK2,PRKG1,BMPR1B |
1.396e-02 | -4.27 | upper_aerodigestive_tract-head_neck-carcinoma-squamous_cell_carcinoma | COSMIC cancer mutations | upper_aerodigestive_tract-head_neck-carcinoma-squamous_cell_carcinoma | 9263 | 35 | 16828 | 49 |
PCDH9,SASH1,LSAMP,RORA,SOX5,ITPR2,BMPR1B,LRIG1,ATP1A2,TRPS1,NHSL1,DCLK2,ADCY2,PPP2R2B,MGAT4C,MSI2,FBXL7,NFIA,LIFR,PTPRZ1,SORBS1,CTNND2,PRKG1,NEBL,RYR3,MACF1,NTRK2,MAML2,PARD3B,GLIS3,CDH20,QKI,GPC5,NKAIN3,PITPNC1 |
1.399e-02 | -4.27 | PCDH20 (protocadherin 20) | protein interactions | 64881 | 70 | 2 | 19454 | 50 |
MGAT4C,CTNNA2 |
1.402e-02 | -4.27 | kidney-carcinoma | COSMIC cancer mutations | kidney-carcinoma | 3720 | 18 | 16828 | 49 |
DCLK2,PPP2R2B,NTRK2,MAML2,QKI,MSI2,PITPNC1,LIFR,FBXL7,PTPRZ1,RORA,CTNND2,SOX5,ITPR2,PRKG1,BMPR1B,LRIG1,TRPS1 |
1.404e-02 | -4.27 | CTF_NFI_2 | prosite domains | PS51080 | 4 | 1 | 12186 | 43 |
NFIA |
1.404e-02 | -4.27 | PR55_1 | prosite domains | PS01024 | 4 | 1 | 12186 | 43 |
PPP2R2B |
1.404e-02 | -4.27 | PR55_2 | prosite domains | PS01025 | 4 | 1 | 12186 | 43 |
PPP2R2B |
1.404e-02 | -4.27 | NEBULIN | prosite domains | PS51216 | 4 | 1 | 12186 | 43 |
NEBL |
1.404e-02 | -4.27 | CTF_NFI_1 | prosite domains | PS00349 | 4 | 1 | 12186 | 43 |
NFIA |
1.412e-02 | -4.26 | membrane protein complex | cellular component | GO:0098796 | 1261 | 8 | 19108 | 49 |
ATP1A2,RYR3,SLC1A2,CDH20,SORBS1,BMPR1B,CTNNA2,SLC1A3 |
1.418e-02 | -4.26 | hepatocellular_carcinoma | COSMIC cancer mutations | hepatocellular_carcinoma | 14800 | 48 | 16828 | 49 |
RYR3,NEBL,CTNND2,PTPRZ1,PITPNC1,NKAIN3,SLC1A2,SPARCL1,PARD3B,GLIS3,NTRK2,TRPS1,BMPR1B,ITPR2,LSAMP,SLC1A3,PCDH9,NPAS3,NFIA,LIFR,FBXL7,ABLIM1,NRG3,DTNA,NHSL1,MACF1,ATP13A4,PRKG1,SORBS1,GPC5,CDH20,QKI,MAML2,AQP4,CSGALNACT1,ATP1A2,LRIG1,SOX5,ZBTB20,RORA,SASH1,NTM,MGAT4C,RFX4,PPP2R2B,GPM6A,ADCY2,DCLK2 |
1.418e-02 | -4.26 | liver-carcinoma-hepatocellular_carcinoma | COSMIC cancer mutations | liver-carcinoma-hepatocellular_carcinoma | 14800 | 48 | 16828 | 49 |
SOX5,ZBTB20,RORA,SASH1,NTM,CSGALNACT1,ATP1A2,LRIG1,RFX4,GPM6A,PPP2R2B,ADCY2,DCLK2,MGAT4C,SORBS1,MACF1,ATP13A4,PRKG1,MAML2,AQP4,GPC5,QKI,CDH20,SLC1A3,LSAMP,PCDH9,NPAS3,TRPS1,BMPR1B,ITPR2,ABLIM1,NRG3,DTNA,NHSL1,NFIA,LIFR,FBXL7,CTNND2,PTPRZ1,RYR3,NEBL,NTRK2,PITPNC1,NKAIN3,SLC1A2,PARD3B,GLIS3,SPARCL1 |
1.418e-02 | -4.26 | L-alpha-amino acid transmembrane transport | biological process | GO:1902475 | 66 | 2 | 18204 | 50 |
SLC1A2,SLC1A3 |
1.418e-02 | -4.26 | cardiac muscle cell development | biological process | GO:0055013 | 66 | 2 | 18204 | 50 |
PRKG1,NEBL |
1.432e-02 | -4.25 | Long-term depression | KEGG pathways | ko04730 | 60 | 2 | 7161 | 22 |
ITPR2,PRKG1 |
1.432e-02 | -4.25 | Long-term depression | KEGG pathways | hsa04730 | 60 | 2 | 7161 | 22 |
PRKG1,ITPR2 |
1.433e-02 | -4.25 | NFIX (nuclear factor I X) | protein interactions | 4784 | 198 | 3 | 19454 | 50 |
TRPS1,NFIA,SOX5 |
1.437e-02 | -4.24 | HEPHL1 (hephaestin like 1) | protein interactions | 341208 | 71 | 2 | 19454 | 50 |
PPP2R2B,CSGALNACT1 |
1.437e-02 | -4.24 | CRYBG1 (crystallin beta-gamma domain containing 1) | protein interactions | 202 | 71 | 2 | 19454 | 50 |
SPARCL1,CSGALNACT1 |
1.448e-02 | -4.23 | cell differentiation | biological process | GO:0030154 | 3645 | 17 | 18204 | 50 |
BMPR1B,DCLK2,NTM,PRKG1,RORA,GPM6A,SOX5,NTRK2,SLC1A3,NEBL,PTPRZ1,QKI,NFIA,CTNND2,NHSL1,CTNNA2,MSI2 |
1.455e-02 | -4.23 | Corticotropin Activation of Cortisol Production | SMPDB pathways | SMP0000310 | 5 | 1 | 1369 | 4 |
ADCY2 |
1.460e-02 | -4.23 | cellular developmental process | biological process | GO:0048869 | 3648 | 17 | 18204 | 50 |
NFIA,QKI,MSI2,CTNNA2,NHSL1,CTNND2,PRKG1,RORA,NTM,DCLK2,BMPR1B,PTPRZ1,NEBL,SLC1A3,SOX5,NTRK2,GPM6A |
1.476e-02 | -4.22 | PPP3CC (protein phosphatase 3 catalytic subunit gamma) | protein interactions | 5533 | 72 | 2 | 19454 | 50 |
PARD3B,BMPR1B |
1.490e-02 | -4.21 | LIM | pfam domains | PF00412 | 69 | 2 | 17795 | 48 |
ABLIM1,NEBL |
1.492e-02 | -4.21 | TIAM1 (TIAM Rac1 associated GEF 1) | protein interactions | 7074 | 201 | 3 | 19454 | 50 |
RYR3,DTNA,ATP1A2 |
1.500e-02 | -4.20 | adenoid_cystic_carcinoma | COSMIC cancer mutations | adenoid_cystic_carcinoma | 1123 | 8 | 16828 | 49 |
PRKG1,MGAT4C,CTNND2,LIFR,MAML2,NTRK2,RORA,RYR3 |
1.501e-02 | -4.20 | lung-carcinoid-endocrine_tumour | COSMIC cancer mutations | lung-carcinoid-endocrine_tumour | 502 | 5 | 16828 | 49 |
DCLK2,PRKG1,SASH1,BMPR1B,NTRK2 |
1.510e-02 | -4.19 | regulation of lipid biosynthetic process | biological process | GO:0046890 | 189 | 3 | 18204 | 50 |
SORBS1,ZBTB20,PRKG1 |
1.512e-02 | -4.19 | FEV (FEV transcription factor, ETS family member) | protein interactions | 54738 | 202 | 3 | 19454 | 50 |
SOX5,NFIA,TRPS1 |
1.520e-02 | -4.19 | skin-scalp-carcinoma-squamous_cell_carcinoma | COSMIC cancer mutations | skin-scalp-carcinoma-squamous_cell_carcinoma | 1596 | 10 | 16828 | 49 |
PTPRZ1,LSAMP,RORA,SOX5,PRKG1,GPC5,ATP13A4,MACF1,TRPS1,ATP1A2 |
1.521e-02 | -4.19 | plasma membrane region | cellular component | GO:0098590 | 1278 | 8 | 19108 | 49 |
SLC1A2,SORBS1,SLC1A3,GPM6A,MACF1,AQP4,ATP1A2,PARD3B |
1.526e-02 | -4.18 | positive regulation of multicellular organismal process | biological process | GO:0051240 | 1691 | 10 | 18204 | 50 |
PTPRZ1,SOX5,NTRK2,ATP1A2,ZBTB20,RORA,BMPR1B,QKI,SASH1,MACF1 |
1.532e-02 | -4.18 | PBP2 (Pbp2p) | protein interactions | 852533 | 6 | 1 | 19454 | 50 |
QKI |
1.532e-02 | -4.18 | GDF6 (growth differentiation factor 6) | protein interactions | 392255 | 6 | 1 | 19454 | 50 |
BMPR1B |
1.532e-02 | -4.18 | DRP2 (dystrophin related protein 2) | protein interactions | 1821 | 6 | 1 | 19454 | 50 |
DTNA |
1.532e-02 | -4.18 | SOX1 (SRY-box transcription factor 1) | protein interactions | 6656 | 6 | 1 | 19454 | 50 |
SOX5 |
1.532e-02 | -4.18 | Itch (itchy, E3 ubiquitin protein ligase) | protein interactions | 16396 | 6 | 1 | 19454 | 50 |
GLIS3 |
1.532e-02 | -4.18 | Fancl (Fanconi anemia, complementation group L) | protein interactions | 67030 | 6 | 1 | 19454 | 50 |
BMPR1B |
1.532e-02 | -4.18 | LIF (LIF interleukin 6 family cytokine) | protein interactions | 3976 | 6 | 1 | 19454 | 50 |
LIFR |
1.532e-02 | -4.18 | DAZ4 (deleted in azoospermia 4) | protein interactions | 57135 | 6 | 1 | 19454 | 50 |
QKI |
1.532e-02 | -4.18 | Tiam2 (T cell lymphoma invasion and metastasis 2) | protein interactions | 24001 | 6 | 1 | 19454 | 50 |
DTNA |
1.532e-02 | -4.18 | SOX11 (SRY-box transcription factor 11) | protein interactions | 6664 | 6 | 1 | 19454 | 50 |
SOX5 |
1.532e-02 | -4.18 | Rhod (ras homolog family member D) | protein interactions | 11854 | 6 | 1 | 19454 | 50 |
BMPR1B |
1.532e-02 | -4.18 | Map2k3 (mitogen-activated protein kinase kinase 3) | protein interactions | 26397 | 6 | 1 | 19454 | 50 |
BMPR1B |
1.532e-02 | -4.18 | TPPP3 (tubulin polymerization promoting protein family member 3) | protein interactions | 51673 | 6 | 1 | 19454 | 50 |
PPP2R2B |
1.532e-02 | -4.18 | CYRIA (CYFIP related Rac1 interactor A) | protein interactions | 81553 | 6 | 1 | 19454 | 50 |
GPM6A |
1.532e-02 | -4.18 | SLC12A5 (solute carrier family 12 member 5) | protein interactions | 57468 | 6 | 1 | 19454 | 50 |
GPM6A |
1.532e-02 | -4.18 | Zbtb2 (zinc finger and BTB domain containing 2) | protein interactions | 381990 | 6 | 1 | 19454 | 50 |
SORBS1 |
1.532e-02 | -4.18 | ADCY1 (adenylate cyclase 1) | protein interactions | 107 | 6 | 1 | 19454 | 50 |
ADCY2 |
1.547e-02 | -4.17 | cell-cell contact zone | cellular component | GO:0044291 | 74 | 2 | 19108 | 49 |
PCDH9,ATP1A2 |
1.552e-02 | -4.17 | NFIC (nuclear factor I C) | protein interactions | 4782 | 204 | 3 | 19454 | 50 |
TRPS1,NFIA,SOX5 |
1.552e-02 | -4.17 | CASK (calcium/calmodulin dependent serine protein kinase) | protein interactions | 8573 | 204 | 3 | 19454 | 50 |
PARD3B,DTNA,ABLIM1 |
1.555e-02 | -4.16 | NEBU | smart domains | SM00227 | 4 | 1 | 9717 | 38 |
NEBL |
1.561e-02 | -4.16 | monoatomic ion transport | biological process | GO:0006811 | 964 | 7 | 18204 | 50 |
ITPR2,ATP13A4,ATP1A2,RYR3,SLC1A3,SLC1A2,GPM6A |
1.576e-02 | -4.15 | cell projection organization | biological process | GO:0030030 | 1200 | 8 | 18204 | 50 |
ABLIM1,GPM6A,CTNND2,CTNNA2,PTPRZ1,RFX4,BMPR1B,PRKG1 |
1.576e-02 | -4.15 | Znf_LIM | interpro domains | IPR001781 | 71 | 2 | 18521 | 50 |
ABLIM1,NEBL |
1.581e-02 | -4.15 | glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity | molecular function | GO:0047238 | 6 | 1 | 18094 | 48 |
CSGALNACT1 |
1.581e-02 | -4.15 | steroid hormone binding | molecular function | GO:1990239 | 6 | 1 | 18094 | 48 |
ATP1A2 |
1.581e-02 | -4.15 | ciliary neurotrophic factor receptor binding | molecular function | GO:0005127 | 6 | 1 | 18094 | 48 |
LIFR |
1.581e-02 | -4.15 | calcium-induced calcium release activity | molecular function | GO:0048763 | 6 | 1 | 18094 | 48 |
RYR3 |
1.598e-02 | -4.14 | cell adhesion molecule binding | molecular function | GO:0050839 | 560 | 5 | 18094 | 48 |
CTNND2,MACF1,PTPRZ1,CDH20,CTNNA2 |
1.598e-02 | -4.14 | ALPHACATENIN | prints domains | PR00805 | 4 | 1 | 5227 | 21 |
CTNNA2 |
1.598e-02 | -4.14 | PP2APR55 | prints domains | PR00600 | 4 | 1 | 5227 | 21 |
PPP2R2B |
1.600e-02 | -4.13 | lung-middle_lobe-carcinoma-adenocarcinoma | COSMIC cancer mutations | lung-middle_lobe-carcinoma-adenocarcinoma | 1368 | 9 | 16828 | 49 |
SASH1,PCDH9,CTNND2,ITPR2,PARD3B,ATP1A2,MACF1,ATP13A4,RYR3 |
1.600e-02 | -4.13 | other | COSMIC cancer mutations | other | 14843 | 48 | 16828 | 49 |
PRKG1,MACF1,ATP13A4,SORBS1,GPC5,QKI,CDH20,AQP4,MAML2,ATP1A2,CSGALNACT1,LRIG1,SASH1,NTM,SOX5,ZBTB20,RORA,MGAT4C,DCLK2,ADCY2,RFX4,PPP2R2B,GPM6A,NEBL,RYR3,PTPRZ1,CTNND2,SLC1A2,SPARCL1,GLIS3,PARD3B,NKAIN3,NTRK2,BMPR1B,ITPR2,TRPS1,LSAMP,SLC1A3,PCDH9,NPAS3,MSI2,FBXL7,LIFR,NFIA,DTNA,NHSL1,NRG3,ABLIM1 |
1.608e-02 | -4.13 | GAS2 | pfam domains | PF02187 | 6 | 1 | 17795 | 48 |
MACF1 |
1.608e-02 | -4.13 | EF-hand_3 | pfam domains | PF09069 | 6 | 1 | 17795 | 48 |
DTNA |
1.608e-02 | -4.13 | SH3_10 | pfam domains | PF17902 | 6 | 1 | 17795 | 48 |
MACF1 |
1.608e-02 | -4.13 | Adcy_cons_dom | pfam domains | PF06327 | 6 | 1 | 17795 | 48 |
ADCY2 |
1.608e-02 | -4.13 | Glypican | pfam domains | PF01153 | 6 | 1 | 17795 | 48 |
GPC5 |
1.608e-02 | -4.13 | Plectin | pfam domains | PF00681 | 6 | 1 | 17795 | 48 |
MACF1 |
1.608e-02 | -4.13 | EF-hand_2 | pfam domains | PF09068 | 6 | 1 | 17795 | 48 |
DTNA |
1.609e-02 | -4.13 | Glypican_CS | interpro domains | IPR019803 | 6 | 1 | 18521 | 50 |
GPC5 |
1.609e-02 | -4.13 | GAR_dom_sf | interpro domains | IPR036534 | 6 | 1 | 18521 | 50 |
MACF1 |
1.609e-02 | -4.13 | Glypican | interpro domains | IPR001863 | 6 | 1 | 18521 | 50 |
GPC5 |
1.609e-02 | -4.13 | EF-hand_dom_typ1 | interpro domains | IPR015153 | 6 | 1 | 18521 | 50 |
DTNA |
1.609e-02 | -4.13 | GLI-like | interpro domains | IPR043359 | 6 | 1 | 18521 | 50 |
GLIS3 |
1.609e-02 | -4.13 | Adcy_conserved_dom | interpro domains | IPR009398 | 6 | 1 | 18521 | 50 |
ADCY2 |
1.609e-02 | -4.13 | EF-hand_dom_typ2 | interpro domains | IPR015154 | 6 | 1 | 18521 | 50 |
DTNA |
1.609e-02 | -4.13 | Desmoplakin_SH3 | interpro domains | IPR041615 | 6 | 1 | 18521 | 50 |
MACF1 |
1.609e-02 | -4.13 | P-type_ATPase_IIC | interpro domains | IPR005775 | 6 | 1 | 18521 | 50 |
ATP1A2 |
1.609e-02 | -4.13 | GAR_dom | interpro domains | IPR003108 | 6 | 1 | 18521 | 50 |
MACF1 |
1.614e-02 | -4.13 | Signaling by EGFR | REACTOME pathways | R-HSA-177929 | 364 | 4 | 10285 | 28 |
LRIG1,NRG3,ADCY2,ITPR2 |
1.618e-02 | -4.12 | protein homooligomerization | biological process | GO:0051260 | 194 | 3 | 18204 | 50 |
RYR3,SLC1A2,AQP4 |
1.622e-02 | -4.12 | salivary_gland | COSMIC cancer mutations | salivary_gland | 1139 | 8 | 16828 | 49 |
NTRK2,RORA,RYR3,CTNND2,MAML2,LIFR,MGAT4C,PRKG1 |
1.623e-02 | -4.12 | Activation of TRKA receptors | REACTOME pathways | R-HSA-187015 | 6 | 1 | 10285 | 28 |
NTRK2 |
1.627e-02 | -4.12 | sarcoplasmic reticulum | cellular component | GO:0016529 | 76 | 2 | 19108 | 49 |
RYR3,ITPR2 |
1.635e-02 | -4.11 | MIR200A (microRNA 200a) | protein interactions | 406983 | 76 | 2 | 19454 | 50 |
MSI2,QKI |
1.637e-02 | -4.11 | regulation of protein autoubiquitination | biological process | GO:1902498 | 6 | 1 | 18204 | 50 |
SASH1 |
1.637e-02 | -4.11 | asymmetric neuroblast division | biological process | GO:0055059 | 6 | 1 | 18204 | 50 |
SOX5 |
1.637e-02 | -4.11 | fused antrum stage | biological process | GO:0048165 | 6 | 1 | 18204 | 50 |
BMPR1B |
1.637e-02 | -4.11 | gamma-aminobutyric acid biosynthetic process | biological process | GO:0009449 | 6 | 1 | 18204 | 50 |
SLC1A3 |
1.637e-02 | -4.11 | intracellular water homeostasis | biological process | GO:0009992 | 6 | 1 | 18204 | 50 |
AQP4 |
1.637e-02 | -4.11 | mammary gland formation | biological process | GO:0060592 | 6 | 1 | 18204 | 50 |
NRG3 |
1.637e-02 | -4.11 | ERBB4-ERBB4 signaling pathway | biological process | GO:0038138 | 6 | 1 | 18204 | 50 |
NRG3 |
1.637e-02 | -4.11 | relaxation of vascular associated smooth muscle | biological process | GO:0060087 | 6 | 1 | 18204 | 50 |
PRKG1 |
1.664e-02 | -4.10 | cell-cell adhesion | biological process | GO:0098609 | 546 | 5 | 18204 | 50 |
SPARCL1,PCDH9,CTNND2,CDH20,CTNNA2 |
1.675e-02 | -4.09 | ABI1 (abl interactor 1) | protein interactions | 10006 | 210 | 3 | 19454 | 50 |
SLC1A3,NHSL1,SORBS1 |
1.680e-02 | -4.09 | embryonal | COSMIC cancer mutations | embryonal | 2659 | 14 | 16828 | 49 |
AQP4,MAML2,ADCY2,NFIA,GLIS3,SPARCL1,PARD3B,RORA,CTNND2,NPAS3,PTPRZ1,SORBS1,RYR3,MACF1 |
1.680e-02 | -4.09 | soft_tissue-striated_muscle-rhabdomyosarcoma-embryonal | COSMIC cancer mutations | soft_tissue-striated_muscle-rhabdomyosarcoma-embryonal | 2659 | 14 | 16828 | 49 |
MACF1,RYR3,SORBS1,NPAS3,PTPRZ1,CTNND2,RORA,PARD3B,GLIS3,SPARCL1,NFIA,ADCY2,MAML2,AQP4 |
1.689e-02 | -4.08 | Diseases of signal transduction | REACTOME pathways | R-HSA-5663202 | 369 | 4 | 10285 | 28 |
NRG3,MAML2,MACF1,QKI |
1.701e-02 | -4.07 | middle_lobe | COSMIC cancer mutations | middle_lobe | 1382 | 9 | 16828 | 49 |
CTNND2,SASH1,PCDH9,ATP1A2,MACF1,ATP13A4,RYR3,PARD3B,ITPR2 |
1.705e-02 | -4.07 | HAD_sf | interpro domains | IPR023214 | 74 | 2 | 18521 | 50 |
ATP1A2,ATP13A4 |
1.709e-02 | -4.07 | skin-extremity-malignant_melanoma | COSMIC cancer mutations | skin-extremity-malignant_melanoma | 1875 | 11 | 16828 | 49 |
ADCY2,PTPRZ1,PCDH9,SASH1,NTRK2,CDH20,NEBL,ATP13A4,RYR3,FBXL7,PITPNC1 |
1.709e-02 | -4.07 | human chr4q22.3 | chromosome location | human chr4q22.3 | 9 | 1 | 26134 | 50 |
BMPR1B |
1.711e-02 | -4.07 | Oncogenic MAPK signaling | REACTOME pathways | R-HSA-6802957 | 74 | 2 | 10285 | 28 |
MACF1,QKI |
1.715e-02 | -4.07 | extremity | COSMIC cancer mutations | extremity | 1876 | 11 | 16828 | 49 |
SASH1,ADCY2,PTPRZ1,PCDH9,NTRK2,CDH20,FBXL7,PITPNC1,ATP13A4,NEBL,RYR3 |
1.716e-02 | -4.07 | vasculogenesis | biological process | GO:0001570 | 73 | 2 | 18204 | 50 |
QKI,NTRK2 |
1.716e-02 | -4.07 | cardiac cell development | biological process | GO:0055006 | 73 | 2 | 18204 | 50 |
NEBL,PRKG1 |
1.717e-02 | -4.06 | Nedd4 (NEDD4 E3 ubiquitin protein ligase) | protein interactions | 25489 | 78 | 2 | 19454 | 50 |
NTRK2,BMPR1B |
1.717e-02 | -4.06 | ATP2B3 (ATPase plasma membrane Ca2+ transporting 3) | protein interactions | 492 | 78 | 2 | 19454 | 50 |
CSGALNACT1,GPM6A |
1.717e-02 | -4.06 | MIR34C (microRNA 34c) | protein interactions | 407042 | 78 | 2 | 19454 | 50 |
QKI,MSI2 |
1.717e-02 | -4.06 | ANKRD40 (ankyrin repeat domain 40) | protein interactions | 91369 | 78 | 2 | 19454 | 50 |
MSI2,SOX5 |
1.718e-02 | -4.06 | Calcium signaling pathway | KEGG pathways | hsa04020 | 181 | 3 | 7161 | 22 |
ADCY2,RYR3,ITPR2 |
1.718e-02 | -4.06 | Calcium signaling pathway | KEGG pathways | ko04020 | 181 | 3 | 7161 | 22 |
ITPR2,RYR3,ADCY2 |
1.735e-02 | -4.05 | autonomic_ganglia-paraganglioma-benign | COSMIC cancer mutations | autonomic_ganglia-paraganglioma-benign | 6 | 1 | 16828 | 49 |
NHSL1 |
1.738e-02 | -4.05 | signaling | biological process | GO:0023052 | 4968 | 21 | 18204 | 50 |
ITPR2,SORBS1,NFIA,SLC1A2,CTNND2,ATP1A2,BMPR1B,DCLK2,SPARCL1,MACF1,DTNA,RORA,PRKG1,ADCY2,SLC1A3,NTRK2,RYR3,NRG3,MAML2,PITPNC1,LIFR |
1.744e-02 | -4.05 | Dopamine Activation of Neurological Reward System | SMPDB pathways | SMP0000308 | 6 | 1 | 1369 | 4 |
ADCY2 |
1.744e-02 | -4.05 | Intracellular Signalling Through PGD2 receptor and Prostaglandin D2 | SMPDB pathways | SMP0000343 | 6 | 1 | 1369 | 4 |
ADCY2 |
1.759e-02 | -4.04 | PRDM1 (PR/SET domain 1) | protein interactions | 639 | 79 | 2 | 19454 | 50 |
NFIA,TRPS1 |
1.761e-02 | -4.04 | positive regulation of gliogenesis | biological process | GO:0014015 | 74 | 2 | 18204 | 50 |
PTPRZ1,QKI |
1.767e-02 | -4.04 | mannosyl-glycoprotein N-acetylglucosaminyltransferases | BIOCYC pathways | META_PWY-7426 | 8 | 1 | 902 | 2 |
MGAT4C |
1.769e-02 | -4.03 | prostate-adenoma | COSMIC cancer mutations | prostate-adenoma | 1634 | 10 | 16828 | 49 |
PRKG1,GPC5,NEBL,MACF1,PTPRZ1,NPAS3,DCLK2,SASH1,SOX5,ZBTB20 |
1.770e-02 | -4.03 | Plakin repeat | gene3d domains | 3.90.1290.10 | 6 | 1 | 14470 | 43 |
MACF1 |
1.770e-02 | -4.03 | Gas2-like domain | gene3d domains | 3.30.920.20 | 6 | 1 | 14470 | 43 |
MACF1 |
1.770e-02 | -4.03 | Single helix bin | gene3d domains | 1.20.5.490 | 6 | 1 | 14470 | 43 |
PRKG1 |
1.786e-02 | -4.03 | Uhmk1 (U2AF homology motif (UHM) kinase 1) | protein interactions | 16589 | 7 | 1 | 19454 | 50 |
BMPR1B |
1.786e-02 | -4.03 | SASH3 (SAM and SH3 domain containing 3) | protein interactions | 54440 | 7 | 1 | 19454 | 50 |
BMPR1B |
1.786e-02 | -4.03 | RGMB (repulsive guidance molecule BMP co-receptor b) | protein interactions | 285704 | 7 | 1 | 19454 | 50 |
BMPR1B |
1.786e-02 | -4.03 | ABCC12 (ATP binding cassette subfamily C member 12) | protein interactions | 94160 | 7 | 1 | 19454 | 50 |
NPAS3 |
1.786e-02 | -4.03 | Fbxo3 (F-box protein 3) | protein interactions | 57443 | 7 | 1 | 19454 | 50 |
BMPR1B |
1.786e-02 | -4.03 | ZBTB45 (zinc finger and BTB domain containing 45) | protein interactions | 84878 | 7 | 1 | 19454 | 50 |
ZBTB20 |
1.786e-02 | -4.03 | SLC16A5 (solute carrier family 16 member 5) | protein interactions | 9121 | 7 | 1 | 19454 | 50 |
PTPRZ1 |
1.786e-02 | -4.03 | Smad7 (SMAD family member 7) | protein interactions | 17131 | 7 | 1 | 19454 | 50 |
BMPR1B |
1.786e-02 | -4.03 | Smurf1 (SMAD specific E3 ubiquitin protein ligase 1) | protein interactions | 75788 | 7 | 1 | 19454 | 50 |
GLIS3 |
1.786e-02 | -4.03 | Pum2 (pumilio RNA-binding family member 2) | protein interactions | 80913 | 7 | 1 | 19454 | 50 |
QKI |
1.790e-02 | -4.02 | axonogenesis | biological process | GO:0007409 | 366 | 4 | 18204 | 50 |
PTPRZ1,CTNNA2,PRKG1,BMPR1B |
1.791e-02 | -4.02 | monoatomic cation transport | biological process | GO:0006812 | 766 | 6 | 18204 | 50 |
GPM6A,SLC1A3,RYR3,ATP1A2,ATP13A4,ITPR2 |
1.815e-02 | -4.01 | soft_tissue-striated_muscle-rhabdomyosarcoma-alveolar | COSMIC cancer mutations | soft_tissue-striated_muscle-rhabdomyosarcoma-alveolar | 2414 | 13 | 16828 | 49 |
NHSL1,PPP2R2B,CDH20,SPARCL1,PARD3B,NFIA,SLC1A3,SORBS1,SASH1,NPAS3,MACF1,TRPS1,RYR3 |
1.815e-02 | -4.01 | alveolar | COSMIC cancer mutations | alveolar | 2414 | 13 | 16828 | 49 |
RYR3,MACF1,TRPS1,NPAS3,SLC1A3,SORBS1,SASH1,CDH20,PARD3B,SPARCL1,NFIA,NHSL1,PPP2R2B |
1.826e-02 | -4.00 | GFAP (glial fibrillary acidic protein) | protein interactions | 2670 | 217 | 3 | 19454 | 50 |
ABLIM1,RORA,NKAIN3 |
1.830e-02 | -4.00 | Glycosaminoglycan biosynthesis, chondroitin sulfate backbone | KEGG pathways | hsa_M00058 | 6 | 1 | 7161 | 22 |
CSGALNACT1 |
1.830e-02 | -4.00 | Glycosaminoglycan biosynthesis, chondroitin sulfate backbone | KEGG pathways | M00058 | 6 | 1 | 7161 | 22 |
CSGALNACT1 |
1.836e-02 | -4.00 | plasma membrane protein complex | cellular component | GO:0098797 | 600 | 5 | 19108 | 49 |
SORBS1,ATP1A2,CDH20,CTNNA2,BMPR1B |
1.843e-02 | -3.99 | P-type sodium:potassium-exchanging transporter activity | molecular function | GO:0005391 | 7 | 1 | 18094 | 48 |
ATP1A2 |
1.843e-02 | -3.99 | P-type sodium transporter activity | molecular function | GO:0008554 | 7 | 1 | 18094 | 48 |
ATP1A2 |
1.843e-02 | -3.99 | mitogen-activated protein kinase p38 binding | molecular function | GO:0048273 | 7 | 1 | 18094 | 48 |
PRKG1 |
1.843e-02 | -3.99 | phosphatidic acid transfer activity | molecular function | GO:1990050 | 7 | 1 | 18094 | 48 |
PITPNC1 |
1.843e-02 | -3.99 | SOX17 (SRY-box transcription factor 17) | protein interactions | 64321 | 81 | 2 | 19454 | 50 |
NFIA,TRPS1 |
1.843e-02 | -3.99 | KLHL15 (kelch like family member 15) | protein interactions | 80311 | 81 | 2 | 19454 | 50 |
PPP2R2B,DCLK2 |
1.865e-02 | -3.98 | Ion channel transport | REACTOME pathways | R-HSA-983712 | 209 | 3 | 10285 | 28 |
ATP1A2,ATP13A4,RYR3 |
1.865e-02 | -3.98 | Protein_kinase_ATP_BS | interpro domains | IPR017441 | 377 | 4 | 18521 | 50 |
PRKG1,BMPR1B,DCLK2,NTRK2 |
1.872e-02 | -3.98 | calcium ion transmembrane transport | biological process | GO:0070588 | 205 | 3 | 18204 | 50 |
ITPR2,GPM6A,RYR3 |
1.873e-02 | -3.98 | SPARC_Ca_bdg | pfam domains | PF10591 | 7 | 1 | 17795 | 48 |
SPARCL1 |
1.873e-02 | -3.98 | TGF_beta_GS | pfam domains | PF08515 | 7 | 1 | 17795 | 48 |
BMPR1B |
1.875e-02 | -3.98 | Plectin_repeat | interpro domains | IPR001101 | 7 | 1 | 18521 | 50 |
MACF1 |
1.875e-02 | -3.98 | Plakophilin/d_Catenin | interpro domains | IPR028435 | 7 | 1 | 18521 | 50 |
CTNND2 |
1.875e-02 | -3.98 | Plakin_repeat_sf | interpro domains | IPR035915 | 7 | 1 | 18521 | 50 |
MACF1 |
1.875e-02 | -3.98 | Aquaporin_transptr | interpro domains | IPR034294 | 7 | 1 | 18521 | 50 |
AQP4 |
1.875e-02 | -3.98 | SPARC/Testican_Ca-bd-dom | interpro domains | IPR019577 | 7 | 1 | 18521 | 50 |
SPARCL1 |
1.875e-02 | -3.98 | Hematopoietin_rcpt_Gp130_CS | interpro domains | IPR003529 | 7 | 1 | 18521 | 50 |
LIFR |
1.875e-02 | -3.98 | Alpha-catenin/vinculin-like_sf | interpro domains | IPR036723 | 7 | 1 | 18521 | 50 |
CTNNA2 |
1.875e-02 | -3.98 | GS_dom | interpro domains | IPR003605 | 7 | 1 | 18521 | 50 |
BMPR1B |
1.875e-02 | -3.98 | LRRNT | smart domains | SM00013 | 54 | 2 | 9717 | 38 |
LRIG1,NTRK2 |
1.882e-02 | -3.97 | HAD-like_sf | interpro domains | IPR036412 | 78 | 2 | 18521 | 50 |
ATP13A4,ATP1A2 |
1.886e-02 | -3.97 | TNNT1 (troponin T1, slow skeletal type) | protein interactions | 7138 | 82 | 2 | 19454 | 50 |
BMPR1B,PRKG1 |
1.896e-02 | -3.97 | Immunoglobulins | gene3d domains | 2.60.40.10 | 721 | 6 | 14470 | 43 |
LIFR,NTRK2,LSAMP,NTM,PTPRZ1,LRIG1 |
1.897e-02 | -3.96 | human chr12p11.23 | chromosome location | human chr12p11.23 | 10 | 1 | 26134 | 50 |
ITPR2 |
1.897e-02 | -3.96 | human chr9p24.2 | chromosome location | human chr9p24.2 | 10 | 1 | 26134 | 50 |
GLIS3 |
1.898e-02 | -3.96 | neural retina development | biological process | GO:0003407 | 77 | 2 | 18204 | 50 |
GPM6A,NTRK2 |
1.898e-02 | -3.96 | positive regulation of axonogenesis | biological process | GO:0050772 | 77 | 2 | 18204 | 50 |
MACF1,NTRK2 |
1.898e-02 | -3.96 | regulation of organic acid transport | biological process | GO:0032890 | 77 | 2 | 18204 | 50 |
ATP1A2,PRKG1 |
1.898e-02 | -3.96 | BMP signaling pathway | biological process | GO:0030509 | 77 | 2 | 18204 | 50 |
NFIA,BMPR1B |
1.902e-02 | -3.96 | testis | COSMIC cancer mutations | testis | 733 | 6 | 16828 | 49 |
BMPR1B,PRKG1,DCLK2,TRPS1,MACF1,NTRK2 |
1.907e-02 | -3.96 | cellular response to magnesium ion | biological process | GO:0071286 | 7 | 1 | 18204 | 50 |
RYR3 |
1.907e-02 | -3.96 | negative regulation of Arp2/3 complex-mediated actin nucleation | biological process | GO:0034316 | 7 | 1 | 18204 | 50 |
CTNNA2 |
1.907e-02 | -3.96 | regulation of oligodendrocyte progenitor proliferation | biological process | GO:0070445 | 7 | 1 | 18204 | 50 |
PTPRZ1 |
1.907e-02 | -3.96 | regulation of testosterone biosynthetic process | biological process | GO:2000224 | 7 | 1 | 18204 | 50 |
PRKG1 |
1.907e-02 | -3.96 | relaxation of smooth muscle | biological process | GO:0044557 | 7 | 1 | 18204 | 50 |
PRKG1 |
1.907e-02 | -3.96 | glial cell fate specification | biological process | GO:0021780 | 7 | 1 | 18204 | 50 |
NFIA |
1.907e-02 | -3.96 | interneuron migration from the subpallium to the cortex | biological process | GO:0021830 | 7 | 1 | 18204 | 50 |
NRG3 |
1.907e-02 | -3.96 | positive regulation of transcription of Notch receptor target | biological process | GO:0007221 | 7 | 1 | 18204 | 50 |
MAML2 |
1.907e-02 | -3.96 | regulation of 3'-UTR-mediated mRNA stabilization | biological process | GO:1905868 | 7 | 1 | 18204 | 50 |
QKI |
1.909e-02 | -3.96 | cell communication | biological process | GO:0007154 | 5010 | 21 | 18204 | 50 |
SLC1A2,CTNND2,ATP1A2,ITPR2,SORBS1,NFIA,NTRK2,SLC1A3,RYR3,NRG3,MAML2,PITPNC1,LIFR,BMPR1B,DCLK2,SPARCL1,MACF1,DTNA,PRKG1,RORA,ADCY2 |
1.909e-02 | -3.96 | solute:sodium symporter activity | molecular function | GO:0015370 | 80 | 2 | 18094 | 48 |
SLC1A2,SLC1A3 |
1.917e-02 | -3.95 | Synaptic Vesicle Pathway | WikiPathways | WP2267 | 52 | 2 | 5310 | 22 |
ATP1A2,SLC1A3 |
1.921e-02 | -3.95 | caveola | cellular component | GO:0005901 | 83 | 2 | 19108 | 49 |
ATP1A2,SORBS1 |
1.930e-02 | -3.95 | PAX2 (paired box 2) | protein interactions | 5076 | 83 | 2 | 19454 | 50 |
NFIA,TRPS1 |
1.939e-02 | -3.94 | YWHAQ (tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein theta) | protein interactions | 10971 | 1076 | 7 | 19454 | 50 |
MACF1,DCLK2,PARD3B,NHSL1,SASH1,ABLIM1,SORBS1 |
1.944e-02 | -3.94 | regulation of glucose transmembrane transport | biological process | GO:0010827 | 78 | 2 | 18204 | 50 |
SORBS1,SLC1A2 |
1.944e-02 | -3.94 | positive regulation of carbohydrate metabolic process | biological process | GO:0045913 | 78 | 2 | 18204 | 50 |
SORBS1,ZBTB20 |
1.954e-02 | -3.94 | SH3-like_dom_sf | interpro domains | IPR036028 | 212 | 3 | 18521 | 50 |
NEBL,SORBS1,SASH1 |
1.954e-02 | -3.94 | transmembrane receptor protein kinase activity | molecular function | GO:0019199 | 81 | 2 | 18094 | 48 |
BMPR1B,NTRK2 |
1.962e-02 | -3.93 | TGM1 (transglutaminase 1) | protein interactions | 7051 | 223 | 3 | 19454 | 50 |
CSGALNACT1,QKI,PPP2R2B |
1.973e-02 | -3.93 | regulation of neurogenesis | biological process | GO:0050767 | 377 | 4 | 18204 | 50 |
PTPRZ1,NTRK2,MACF1,QKI |
1.976e-02 | -3.92 | FBXO2 (F-box protein 2) | protein interactions | 26232 | 403 | 4 | 19454 | 50 |
NTM,LRIG1,LIFR,PCDH9 |
1.977e-02 | -3.92 | NGF signalling via TRKA from the plasma membrane | REACTOME pathways | R-HSA-187037 | 387 | 4 | 10285 | 28 |
NRG3,NTRK2,ADCY2,ITPR2 |
1.978e-02 | -3.92 | cytoskeleton organization | biological process | GO:0007010 | 1251 | 8 | 18204 | 50 |
PRKG1,PARD3B,DCLK2,SORBS1,MACF1,CTNNA2,ABLIM1,NEBL |
1.984e-02 | -3.92 | Cysteine Rich Protein | gene3d domains | 2.10.110.10 | 73 | 2 | 14470 | 43 |
NEBL,ABLIM1 |
1.985e-02 | -3.92 | MAPRE3 (microtubule associated protein RP/EB family member 3) | protein interactions | 22924 | 224 | 3 | 19454 | 50 |
MACF1,GPM6A,ABLIM1 |
1.991e-02 | -3.92 | regulation of glial cell differentiation | biological process | GO:0045685 | 79 | 2 | 18204 | 50 |
PTPRZ1,QKI |
1.993e-02 | -3.92 | PITRANSFER | prints domains | PR00391 | 5 | 1 | 5227 | 21 |
PITPNC1 |
2.008e-02 | -3.91 | KLF3 (KLF transcription factor 3) | protein interactions | 51274 | 225 | 3 | 19454 | 50 |
TRPS1,NFIA,SOX5 |
2.023e-02 | -3.90 | Adherens junction | KEGG pathways | hsa04520 | 72 | 2 | 7161 | 22 |
SORBS1,CTNNA2 |
2.023e-02 | -3.90 | Adherens junction | KEGG pathways | ko04520 | 72 | 2 | 7161 | 22 |
SORBS1,CTNNA2 |
2.032e-02 | -3.90 | Vasopressin Regulation of Water Homeostasis | SMPDB pathways | SMP0000322 | 7 | 1 | 1369 | 4 |
ADCY2 |
2.034e-02 | -3.90 | zonula adherens | cellular component | GO:0005915 | 8 | 1 | 19108 | 49 |
SORBS1 |
2.034e-02 | -3.90 | HFE-transferrin receptor complex | cellular component | GO:1990712 | 8 | 1 | 19108 | 49 |
BMPR1B |
2.035e-02 | -3.89 | HAD superfamily/HAD-like | gene3d domains | 3.40.50.1000 | 74 | 2 | 14470 | 43 |
ATP13A4,ATP1A2 |
2.038e-02 | -3.89 | Rps27a (ribosomal protein S27A) | protein interactions | 78294 | 8 | 1 | 19454 | 50 |
BMPR1B |
2.038e-02 | -3.89 | Rasd2 (RASD family, member 2) | protein interactions | 75141 | 8 | 1 | 19454 | 50 |
BMPR1B |
2.038e-02 | -3.89 | INSM1 (INSM transcriptional repressor 1) | protein interactions | 3642 | 8 | 1 | 19454 | 50 |
SORBS1 |
2.038e-02 | -3.89 | DEPP1 (DEPP autophagy regulator 1) | protein interactions | 11067 | 8 | 1 | 19454 | 50 |
QKI |
2.038e-02 | -3.89 | BMP15 (bone morphogenetic protein 15) | protein interactions | 9210 | 8 | 1 | 19454 | 50 |
BMPR1B |
2.038e-02 | -3.89 | LHB (luteinizing hormone subunit beta) | protein interactions | 3972 | 8 | 1 | 19454 | 50 |
NTM |
2.042e-02 | -3.89 | eye development | biological process | GO:0001654 | 381 | 4 | 18204 | 50 |
NFIA,GPM6A,NTRK2,BMPR1B |
2.055e-02 | -3.88 | receptor complex | cellular component | GO:0043235 | 409 | 4 | 19108 | 49 |
NTRK2,LIFR,BMPR1B,ITPR2 |
2.058e-02 | -3.88 | Transmission across Chemical Synapses | REACTOME pathways | R-HSA-112315 | 217 | 3 | 10285 | 28 |
ADCY2,SLC1A2,SLC1A3 |
2.063e-02 | -3.88 | SYNJ1 (synaptojanin 1) | protein interactions | 8867 | 86 | 2 | 19454 | 50 |
GPM6A,SORBS1 |
2.092e-02 | -3.87 | transmembrane transport | biological process | GO:0055085 | 1264 | 8 | 18204 | 50 |
ATP13A4,ITPR2,SLC1A2,GPM6A,AQP4,SLC1A3,RYR3,ATP1A2 |
2.099e-02 | -3.86 | GLYPICAN | prosite domains | PS01207 | 6 | 1 | 12186 | 43 |
GPC5 |
2.099e-02 | -3.86 | GAR | prosite domains | PS51460 | 6 | 1 | 12186 | 43 |
MACF1 |
2.101e-02 | -3.86 | EF_hand_dom | interpro domains | IPR002048 | 218 | 3 | 18521 | 50 |
SPARCL1,MACF1,RYR3 |
2.103e-02 | -3.86 | glutamate binding | molecular function | GO:0016595 | 8 | 1 | 18094 | 48 |
SLC1A3 |
2.103e-02 | -3.86 | P-type potassium transmembrane transporter activity | molecular function | GO:0008556 | 8 | 1 | 18094 | 48 |
ATP1A2 |
2.103e-02 | -3.86 | BMP receptor activity | molecular function | GO:0098821 | 8 | 1 | 18094 | 48 |
BMPR1B |
2.103e-02 | -3.86 | cyclic nucleotide-dependent protein kinase activity | molecular function | GO:0004690 | 8 | 1 | 18094 | 48 |
PRKG1 |
2.103e-02 | -3.86 | sodium ion binding | molecular function | GO:0031402 | 8 | 1 | 18094 | 48 |
ATP1A2 |
2.103e-02 | -3.86 | cellular response to nitrogen compound | biological process | GO:1901699 | 580 | 5 | 18204 | 50 |
ITPR2,SORBS1,SLC1A2,SLC1A3,RYR3 |
2.105e-02 | -3.86 | glutamatergic synapse | cellular component | GO:0098978 | 412 | 4 | 19108 | 49 |
SLC1A2,NRG3,SPARCL1,GPM6A |
2.108e-02 | -3.86 | NHLH1 (nescient helix-loop-helix 1) | protein interactions | 4807 | 87 | 2 | 19454 | 50 |
NFIA,TRPS1 |
2.108e-02 | -3.86 | MIR141 (microRNA 141) | protein interactions | 406933 | 87 | 2 | 19454 | 50 |
QKI,MSI2 |
2.108e-02 | -3.86 | ZNF608 (zinc finger protein 608) | protein interactions | 57507 | 87 | 2 | 19454 | 50 |
NFIA,SOX5 |
2.108e-02 | -3.86 | Kctd5 (potassium channel tetramerisation domain containing 5) | protein interactions | 69259 | 87 | 2 | 19454 | 50 |
TRPS1,SLC1A3 |
2.113e-02 | -3.86 | visual system development | biological process | GO:0150063 | 385 | 4 | 18204 | 50 |
GPM6A,BMPR1B,NTRK2,NFIA |
2.115e-02 | -3.86 | Cys-rich_flank_reg_C | interpro domains | IPR000483 | 83 | 2 | 18521 | 50 |
NTRK2,LRIG1 |
2.117e-02 | -3.86 | sensory organ development | biological process | GO:0007423 | 581 | 5 | 18204 | 50 |
BMPR1B,NTRK2,GPM6A,LRIG1,NFIA |
2.118e-02 | -3.85 | papillary_renal_cell_carcinoma | COSMIC cancer mutations | papillary_renal_cell_carcinoma | 6364 | 26 | 16828 | 49 |
MAML2,NTRK2,GPC5,PITPNC1,PTPRZ1,CTNND2,PRKG1,MACF1,ATP13A4,RYR3,ADCY2,DCLK2,RFX4,NRG3,ABLIM1,LIFR,NFIA,SASH1,NTM,ZBTB20,SOX5,RORA,BMPR1B,ITPR2,ATP1A2,LRIG1 |
2.118e-02 | -3.85 | kidney-carcinoma-papillary_renal_cell_carcinoma | COSMIC cancer mutations | kidney-carcinoma-papillary_renal_cell_carcinoma | 6364 | 26 | 16828 | 49 |
CTNND2,PTPRZ1,RYR3,ATP13A4,MACF1,PRKG1,NTRK2,MAML2,PITPNC1,GPC5,RORA,ZBTB20,SOX5,NTM,SASH1,LRIG1,ATP1A2,ITPR2,BMPR1B,ABLIM1,NRG3,RFX4,DCLK2,ADCY2,LIFR,NFIA |
2.125e-02 | -3.85 | acute_lymphoblastic_leukaemia | COSMIC cancer mutations | acute_lymphoblastic_leukaemia | 2197 | 12 | 16828 | 49 |
PTPRZ1,SOX5,BMPR1B,PRKG1,ATP1A2,TRPS1,DTNA,ADCY2,DCLK2,NTRK2,PARD3B,NFIA |
2.130e-02 | -3.85 | leg | COSMIC cancer mutations | leg | 969 | 7 | 16828 | 49 |
NRG3,ZBTB20,PTPRZ1,NTM,NEBL,ATP13A4,PRKG1 |
2.138e-02 | -3.85 | DCX | pfam domains | PF03607 | 8 | 1 | 17795 | 48 |
DCLK2 |
2.138e-02 | -3.85 | AC_N | pfam domains | PF16214 | 8 | 1 | 17795 | 48 |
ADCY2 |
2.138e-02 | -3.85 | CHGN | pfam domains | PF05679 | 8 | 1 | 17795 | 48 |
CSGALNACT1 |
2.138e-02 | -3.85 | VHP | pfam domains | PF02209 | 8 | 1 | 17795 | 48 |
ABLIM1 |
2.140e-02 | -3.84 | Villin_headpiece | interpro domains | IPR003128 | 8 | 1 | 18521 | 50 |
ABLIM1 |
2.140e-02 | -3.84 | AC_N | interpro domains | IPR032628 | 8 | 1 | 18521 | 50 |
ADCY2 |
2.140e-02 | -3.84 | Villin_headpiece_dom_sf | interpro domains | IPR036886 | 8 | 1 | 18521 | 50 |
ABLIM1 |
2.140e-02 | -3.84 | Plakin | interpro domains | IPR043197 | 8 | 1 | 18521 | 50 |
MACF1 |
2.140e-02 | -3.84 | Chond_GalNAc | interpro domains | IPR008428 | 8 | 1 | 18521 | 50 |
CSGALNACT1 |
2.140e-02 | -3.84 | RFX-like | interpro domains | IPR039779 | 8 | 1 | 18521 | 50 |
RFX4 |
2.140e-02 | -3.84 | Adcy | interpro domains | IPR030672 | 8 | 1 | 18521 | 50 |
ADCY2 |
2.153e-02 | -3.84 | Ig_sub | interpro domains | IPR003599 | 394 | 4 | 18521 | 50 |
NTRK2,NTM,LRIG1,LSAMP |
2.158e-02 | -3.84 | Release of Hh-Np from the secreting cell | REACTOME pathways | R-HSA-5362798 | 8 | 1 | 10285 | 28 |
GPC5 |
2.177e-02 | -3.83 | gamma-aminobutyric acid metabolic process | biological process | GO:0009448 | 8 | 1 | 18204 | 50 |
SLC1A3 |
2.177e-02 | -3.83 | cell proliferation in external granule layer | biological process | GO:0021924 | 8 | 1 | 18204 | 50 |
RORA |
2.177e-02 | -3.83 | ERBB4 signaling pathway | biological process | GO:0038130 | 8 | 1 | 18204 | 50 |
NRG3 |
2.177e-02 | -3.83 | heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process | biological process | GO:0015014 | 8 | 1 | 18204 | 50 |
CSGALNACT1 |
2.177e-02 | -3.83 | dermatan sulfate proteoglycan biosynthetic process | biological process | GO:0050651 | 8 | 1 | 18204 | 50 |
CSGALNACT1 |
2.177e-02 | -3.83 | cerebellar granule cell precursor proliferation | biological process | GO:0021930 | 8 | 1 | 18204 | 50 |
RORA |
2.177e-02 | -3.83 | cell proliferation in hindbrain | biological process | GO:0021534 | 8 | 1 | 18204 | 50 |
RORA |
2.177e-02 | -3.83 | regulation of L-glutamate import across plasma membrane | biological process | GO:0002036 | 8 | 1 | 18204 | 50 |
ATP1A2 |
2.177e-02 | -3.83 | regulation of synapse structural plasticity | biological process | GO:0051823 | 8 | 1 | 18204 | 50 |
CTNNA2 |
2.184e-02 | -3.82 | regulation of amine transport | biological process | GO:0051952 | 83 | 2 | 18204 | 50 |
PRKG1,ATP1A2 |
2.199e-02 | -3.82 | SOX10 (SRY-box transcription factor 10) | protein interactions | 6663 | 89 | 2 | 19454 | 50 |
TRPS1,NFIA |
2.199e-02 | -3.82 | SERPINB13 (serpin family B member 13) | protein interactions | 5275 | 89 | 2 | 19454 | 50 |
CSGALNACT1,PPP2R2B |
2.220e-02 | -3.81 | Opioid Signalling | REACTOME pathways | R-HSA-111885 | 85 | 2 | 10285 | 28 |
ADCY2,ITPR2 |
2.221e-02 | -3.81 | sensory system development | biological process | GO:0048880 | 391 | 4 | 18204 | 50 |
NTRK2,BMPR1B,GPM6A,NFIA |
2.224e-02 | -3.81 | HMG20A (high mobility group 20A) | protein interactions | 10363 | 234 | 3 | 19454 | 50 |
DTNA,SOX5,NFIA |
2.233e-02 | -3.80 | L-amino acid transport | biological process | GO:0015807 | 84 | 2 | 18204 | 50 |
SLC1A2,SLC1A3 |
2.233e-02 | -3.80 | proteoglycan metabolic process | biological process | GO:0006029 | 84 | 2 | 18204 | 50 |
CSGALNACT1,BMPR1B |
2.233e-02 | -3.80 | regulation of sodium ion transport | biological process | GO:0002028 | 84 | 2 | 18204 | 50 |
ATP1A2,NKAIN3 |
2.272e-02 | -3.78 | human chr6q26 | chromosome location | human chr6q26 | 12 | 1 | 26134 | 50 |
QKI |
2.283e-02 | -3.78 | chondrocyte differentiation | biological process | GO:0002062 | 85 | 2 | 18204 | 50 |
SOX5,BMPR1B |
2.283e-02 | -3.78 | oligodendrocyte differentiation | biological process | GO:0048709 | 85 | 2 | 18204 | 50 |
PTPRZ1,NTRK2 |
2.285e-02 | -3.78 | platelet dense tubular network membrane | cellular component | GO:0031095 | 9 | 1 | 19108 | 49 |
ITPR2 |
2.285e-02 | -3.78 | astrocyte end-foot | cellular component | GO:0097450 | 9 | 1 | 19108 | 49 |
AQP4 |
2.285e-02 | -3.78 | flotillin complex | cellular component | GO:0016600 | 9 | 1 | 19108 | 49 |
SORBS1 |
2.290e-02 | -3.78 | VEPH1 (ventricular zone expressed PH domain containing 1) | protein interactions | 79674 | 9 | 1 | 19454 | 50 |
BMPR1B |
2.290e-02 | -3.78 | NRXN2 (neurexin 2) | protein interactions | 9379 | 9 | 1 | 19454 | 50 |
MACF1 |
2.290e-02 | -3.78 | Tyw3 (tRNA-yW synthesizing protein 3 homolog (S. cerevisiae)) | protein interactions | 209584 | 9 | 1 | 19454 | 50 |
CTNNA2 |
2.290e-02 | -3.78 | PI3 (peptidase inhibitor 3) | protein interactions | 5266 | 9 | 1 | 19454 | 50 |
PPP2R2B |
2.290e-02 | -3.78 | IER5 (immediate early response 5) | protein interactions | 51278 | 9 | 1 | 19454 | 50 |
PPP2R2B |
2.290e-02 | -3.78 | Ywhag (tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide) | protein interactions | 22628 | 9 | 1 | 19454 | 50 |
QKI |
2.292e-02 | -3.78 | FOXI1 (forkhead box I1) | protein interactions | 2299 | 91 | 2 | 19454 | 50 |
NFIA,TRPS1 |
2.292e-02 | -3.78 | DGUOK (deoxyguanosine kinase) | protein interactions | 1716 | 91 | 2 | 19454 | 50 |
NTM,GPM6A |
2.299e-02 | -3.77 | CAMK2A (calcium/calmodulin dependent protein kinase II alpha) | protein interactions | 815 | 237 | 3 | 19454 | 50 |
ITPR2,GPM6A,SOX5 |
2.300e-02 | -3.77 | - | gene3d domains | 2.80.10.50 | 79 | 2 | 14470 | 43 |
ITPR2,RYR3 |
2.306e-02 | -3.77 | central_nervous_system-chiasm-glioma-astrocytoma_Grade_I | COSMIC cancer mutations | central_nervous_system-chiasm-glioma-astrocytoma_Grade_I | 8 | 1 | 16828 | 49 |
QKI |
2.318e-02 | -3.76 | skin-leg-malignant_melanoma-superficial_spreading | COSMIC cancer mutations | skin-leg-malignant_melanoma-superficial_spreading | 210 | 3 | 16828 | 49 |
ATP13A4,NTM,PRKG1 |
2.320e-02 | -3.76 | Intracellular Signalling Through Prostacyclin Receptor and Prostacyclin | SMPDB pathways | SMP0000354 | 8 | 1 | 1369 | 4 |
ADCY2 |
2.324e-02 | -3.76 | GAS2 | smart domains | SM00243 | 6 | 1 | 9717 | 38 |
MACF1 |
2.334e-02 | -3.76 | central nervous system neuron development | biological process | GO:0021954 | 86 | 2 | 18204 | 50 |
NTRK2,DCLK2 |
2.336e-02 | -3.76 | Calcium Regulation in the Cardiac Cell | WikiPathways | WP536 | 151 | 3 | 5310 | 22 |
ADCY2,RYR3,ITPR2 |
2.339e-02 | -3.76 | SOX9 (SRY-box transcription factor 9) | protein interactions | 6662 | 92 | 2 | 19454 | 50 |
NFIA,TRPS1 |
2.346e-02 | -3.75 | response to oxygen-containing compound | biological process | GO:1901700 | 1546 | 9 | 18204 | 50 |
RYR3,SLC1A2,SLC1A3,ZBTB20,ATP1A2,RORA,ADCY2,SORBS1,ITPR2 |
2.353e-02 | -3.75 | Villin headpiece domain | gene3d domains | 1.10.950.10 | 8 | 1 | 14470 | 43 |
ABLIM1 |
2.387e-02 | -3.74 | DMRTB1 (DMRT like family B with proline rich C-terminal 1) | protein interactions | 63948 | 93 | 2 | 19454 | 50 |
QKI,MSI2 |
2.387e-02 | -3.74 | ARHGEF6 (Rac/Cdc42 guanine nucleotide exchange factor 6) | protein interactions | 9459 | 93 | 2 | 19454 | 50 |
BMPR1B,ABLIM1 |
2.387e-02 | -3.74 | TEX11 (testis expressed 11) | protein interactions | 56159 | 93 | 2 | 19454 | 50 |
QKI,SOX5 |
2.387e-02 | -3.74 | LGALS7B (galectin 7B) | protein interactions | 653499 | 93 | 2 | 19454 | 50 |
PPP2R2B,CSGALNACT1 |
2.387e-02 | -3.74 | MIR19B2 (microRNA 19b-2) | protein interactions | 406981 | 93 | 2 | 19454 | 50 |
MSI2,QKI |
2.387e-02 | -3.74 | ODR4 (odr-4 GPCR localization factor homolog) | protein interactions | 54953 | 93 | 2 | 19454 | 50 |
GPM6A,LRIG1 |
2.388e-02 | -3.73 | ACTIVIN2R | prints domains | PR00653 | 6 | 1 | 5227 | 21 |
BMPR1B |
2.402e-02 | -3.73 | RFX_DNA_binding | pfam domains | PF02257 | 9 | 1 | 17795 | 48 |
RFX4 |
2.402e-02 | -3.73 | Activin_recp | pfam domains | PF01064 | 9 | 1 | 17795 | 48 |
BMPR1B |
2.404e-02 | -3.73 | Fol_N | interpro domains | IPR003645 | 9 | 1 | 18521 | 50 |
SPARCL1 |
2.404e-02 | -3.73 | Activin_recp | interpro domains | IPR000472 | 9 | 1 | 18521 | 50 |
BMPR1B |
2.404e-02 | -3.73 | Doublecortin_dom | interpro domains | IPR003533 | 9 | 1 | 18521 | 50 |
DCLK2 |
2.404e-02 | -3.73 | DNA-bd_RFX | interpro domains | IPR003150 | 9 | 1 | 18521 | 50 |
RFX4 |
2.408e-02 | -3.73 | ion binding | molecular function | GO:0043167 | 6007 | 23 | 18094 | 48 |
TRPS1,PITPNC1,ITPR2,BMPR1B,DCLK2,SLC1A3,PCDH9,PRKG1,SLC1A2,ADCY2,SPARCL1,DTNA,ATP1A2,RYR3,ABLIM1,CSGALNACT1,GLIS3,RORA,MGAT4C,ZBTB20,NTRK2,ATP13A4,MACF1 |
2.430e-02 | -3.72 | protein binding | molecular function | GO:0005515 | 13983 | 43 | 18094 | 48 |
DTNA,ATP1A2,RYR3,NFIA,PARD3B,SPARCL1,ADCY2,PRKG1,CTNND2,RFX4,SLC1A2,DCLK2,SLC1A3,NTM,FBXL7,ITPR2,BMPR1B,TRPS1,PITPNC1,NRG3,MSI2,NPAS3,LSAMP,SORBS1,NEBL,NTRK2,CDH20,MACF1,AQP4,CTNNA2,QKI,GPM6A,RORA,PPP2R2B,GPC5,MAML2,SOX5,GLIS3,ABLIM1,PTPRZ1,SASH1,LRIG1,LIFR |
2.435e-02 | -3.72 | QSER1 (glutamine and serine rich 1) | protein interactions | 79832 | 94 | 2 | 19454 | 50 |
NFIA,SOX5 |
2.435e-02 | -3.72 | FOXP4 (forkhead box P4) | protein interactions | 116113 | 94 | 2 | 19454 | 50 |
SOX5,NFIA |
2.437e-02 | -3.71 | kidney-carcinoma-renal_cell_carcinoma | COSMIC cancer mutations | kidney-carcinoma-renal_cell_carcinoma | 4535 | 20 | 16828 | 49 |
FBXL7,PITPNC1,LIFR,QKI,MSI2,NTRK2,PPP2R2B,MAML2,DCLK2,LRIG1,TRPS1,MACF1,ITPR2,BMPR1B,PRKG1,RORA,CTNND2,SOX5,PTPRZ1,PCDH9 |
2.437e-02 | -3.71 | renal_cell_carcinoma | COSMIC cancer mutations | renal_cell_carcinoma | 4535 | 20 | 16828 | 49 |
MAML2,PPP2R2B,NTRK2,DCLK2,PITPNC1,LIFR,FBXL7,MSI2,QKI,SOX5,CTNND2,RORA,PCDH9,PTPRZ1,TRPS1,MACF1,LRIG1,PRKG1,BMPR1B,ITPR2 |
2.445e-02 | -3.71 | GS | prosite domains | PS51256 | 7 | 1 | 12186 | 43 |
BMPR1B |
2.445e-02 | -3.71 | HEMATOPO_REC_L_F2 | prosite domains | PS01353 | 7 | 1 | 12186 | 43 |
LIFR |
2.446e-02 | -3.71 | hindbrain radial glia guided cell migration | biological process | GO:0021932 | 9 | 1 | 18204 | 50 |
CTNNA2 |
2.446e-02 | -3.71 | release of sequestered calcium ion into cytosol by sarcoplasmic reticulum | biological process | GO:0014808 | 9 | 1 | 18204 | 50 |
RYR3 |
2.446e-02 | -3.71 | negative regulation of actin nucleation | biological process | GO:0051126 | 9 | 1 | 18204 | 50 |
CTNNA2 |
2.446e-02 | -3.71 | negative regulation of striated muscle contraction | biological process | GO:0045988 | 9 | 1 | 18204 | 50 |
ATP1A2 |
2.446e-02 | -3.71 | polyamine transmembrane transport | biological process | GO:1902047 | 9 | 1 | 18204 | 50 |
ATP13A4 |
2.456e-02 | -3.71 | membrane | cellular component | GO:0016020 | 9220 | 31 | 19108 | 49 |
RYR3,PCDH9,NRG3,NTRK2,CTNND2,ATP13A4,MGAT4C,NKAIN3,CTNNA2,SORBS1,PRKG1,LSAMP,PARD3B,CSGALNACT1,PPP2R2B,GPC5,CDH20,DTNA,NTM,AQP4,ATP1A2,MACF1,PTPRZ1,LIFR,ADCY2,GPM6A,LRIG1,ITPR2,SLC1A3,BMPR1B,SLC1A2 |
2.459e-02 | -3.71 | human chr5p15.1 | chromosome location | human chr5p15.1 | 13 | 1 | 26134 | 50 |
FBXL7 |
2.468e-02 | -3.70 | skeletal system morphogenesis | biological process | GO:0048705 | 228 | 3 | 18204 | 50 |
SOX5,BMPR1B,CSGALNACT1 |
2.487e-02 | -3.69 | positive regulation of lipid biosynthetic process | biological process | GO:0046889 | 89 | 2 | 18204 | 50 |
ZBTB20,SORBS1 |
2.496e-02 | -3.69 | DNA-binding transcription factor activity, RNA polymerase II-specific | molecular function | GO:0000981 | 1355 | 8 | 18094 | 48 |
RORA,RFX4,NPAS3,SOX5,GLIS3,ZBTB20,NFIA,TRPS1 |
2.521e-02 | -3.68 | sarcoplasm | cellular component | GO:0016528 | 96 | 2 | 19108 | 49 |
ITPR2,RYR3 |
2.521e-02 | -3.68 | Platelet homeostasis | REACTOME pathways | R-HSA-418346 | 91 | 2 | 10285 | 28 |
ITPR2,PRKG1 |
2.523e-02 | -3.68 | haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-NK-T_cell_lymphoma | COSMIC cancer mutations | haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-NK-T_cell_lymphoma | 217 | 3 | 16828 | 49 |
RFX4,DTNA,MGAT4C |
2.532e-02 | -3.68 | E7 (E7 protein) | protein interactions | 1489369 | 96 | 2 | 19454 | 50 |
SASH1,QKI |
2.536e-02 | -3.67 | perineuronal net | cellular component | GO:0072534 | 10 | 1 | 19108 | 49 |
PTPRZ1 |
2.541e-02 | -3.67 | BANK1 (B cell scaffold protein with ankyrin repeats 1) | protein interactions | 55024 | 10 | 1 | 19454 | 50 |
ITPR2 |
2.541e-02 | -3.67 | Vbp1 (von Hippel-Lindau binding protein 1) | protein interactions | 22327 | 10 | 1 | 19454 | 50 |
ABLIM1 |
2.541e-02 | -3.67 | P2rx7 (purinergic receptor P2X 7) | protein interactions | 29665 | 10 | 1 | 19454 | 50 |
PTPRZ1 |
2.541e-02 | -3.67 | Hsp90aa1 (heat shock protein 90, alpha (cytosolic), class A member 1) | protein interactions | 15519 | 10 | 1 | 19454 | 50 |
QKI |
2.541e-02 | -3.67 | CALB2 (calbindin 2) | protein interactions | 794 | 10 | 1 | 19454 | 50 |
GPM6A |
2.541e-02 | -3.67 | Mrpl13 (mitochondrial ribosomal protein L13) | protein interactions | 68537 | 10 | 1 | 19454 | 50 |
QKI |
2.541e-02 | -3.67 | SLC8A2 (solute carrier family 8 member A2) | protein interactions | 6543 | 10 | 1 | 19454 | 50 |
GPM6A |
2.541e-02 | -3.67 | Smurf2 (SMAD specific E3 ubiquitin protein ligase 2) | protein interactions | 66313 | 10 | 1 | 19454 | 50 |
GLIS3 |
2.541e-02 | -3.67 | DEFA1B (defensin alpha 1B) | protein interactions | 728358 | 10 | 1 | 19454 | 50 |
PPP2R2B |
2.541e-02 | -3.67 | GSG1 (germ cell associated 1) | protein interactions | 83445 | 10 | 1 | 19454 | 50 |
PITPNC1 |
2.547e-02 | -3.67 | YWHAZ (tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein zeta) | protein interactions | 7534 | 1138 | 7 | 19454 | 50 |
ABLIM1,SORBS1,SASH1,PARD3B,PITPNC1,NHSL1,MACF1 |
2.573e-02 | -3.66 | Post-translational modification: synthesis of GPI-anchored proteins | REACTOME pathways | R-HSA-163125 | 92 | 2 | 10285 | 28 |
LSAMP,NTM |
2.580e-02 | -3.66 | Aldosterone synthesis and secretion | KEGG pathways | ko04925 | 82 | 2 | 7161 | 22 |
ADCY2,ITPR2 |
2.580e-02 | -3.66 | Aldosterone synthesis and secretion | KEGG pathways | hsa04925 | 82 | 2 | 7161 | 22 |
ADCY2,ITPR2 |
2.581e-02 | -3.66 | BTG3 (BTG anti-proliferation factor 3) | protein interactions | 10950 | 97 | 2 | 19454 | 50 |
DCLK2,SPARCL1 |
2.592e-02 | -3.65 | LIM_DOMAIN_1 | prosite domains | PS00478 | 71 | 2 | 12186 | 43 |
NEBL,ABLIM1 |
2.592e-02 | -3.65 | LIM_DOMAIN_2 | prosite domains | PS50023 | 71 | 2 | 12186 | 43 |
NEBL,ABLIM1 |
2.592e-02 | -3.65 | cellular response to BMP stimulus | biological process | GO:0071773 | 91 | 2 | 18204 | 50 |
BMPR1B,NFIA |
2.592e-02 | -3.65 | response to BMP | biological process | GO:0071772 | 91 | 2 | 18204 | 50 |
NFIA,BMPR1B |
2.607e-02 | -3.65 | Excitatory Neural Signalling Through 5-HTR 7 and Serotonin | SMPDB pathways | SMP0000311 | 9 | 1 | 1369 | 4 |
ADCY2 |
2.607e-02 | -3.65 | Intracellular Signalling Through Histamine H2 Receptor and Histamine | SMPDB pathways | SMP0000335 | 9 | 1 | 1369 | 4 |
ADCY2 |
2.607e-02 | -3.65 | Excitatory Neural Signalling Through 5-HTR 4 and Serotonin | SMPDB pathways | SMP0000309 | 9 | 1 | 1369 | 4 |
ADCY2 |
2.607e-02 | -3.65 | Intracellular Signalling Through FSH Receptor and Follicle Stimulating Hormone | SMPDB pathways | SMP0000333 | 9 | 1 | 1369 | 4 |
ADCY2 |
2.607e-02 | -3.65 | Excitatory Neural Signalling Through 5-HTR 6 and Serotonin | SMPDB pathways | SMP0000312 | 9 | 1 | 1369 | 4 |
ADCY2 |
2.621e-02 | -3.64 | oesophagus-carcinoma-adenocarcinoma | COSMIC cancer mutations | oesophagus-carcinoma-adenocarcinoma | 13112 | 44 | 16828 | 49 |
GPC5,CDH20,QKI,AQP4,MAML2,PRKG1,MACF1,ATP13A4,SORBS1,MGAT4C,ADCY2,DCLK2,RFX4,PPP2R2B,GPM6A,ATP1A2,CSGALNACT1,LRIG1,SASH1,NTM,ZBTB20,SOX5,RORA,SLC1A2,PARD3B,SPARCL1,GLIS3,NKAIN3,NTRK2,NEBL,RYR3,PTPRZ1,CTNND2,FBXL7,LIFR,NHSL1,NRG3,BMPR1B,ITPR2,TRPS1,SLC1A3,LSAMP,PCDH9,NPAS3 |
2.622e-02 | -3.64 | phosphatidylinositol transfer activity | molecular function | GO:0008526 | 10 | 1 | 18094 | 48 |
PITPNC1 |
2.622e-02 | -3.64 | neurotrophin binding | molecular function | GO:0043121 | 10 | 1 | 18094 | 48 |
NTRK2 |
2.622e-02 | -3.64 | polyamine transmembrane transporter activity | molecular function | GO:0015203 | 10 | 1 | 18094 | 48 |
ATP13A4 |
2.625e-02 | -3.64 | cell surface | cellular component | GO:0009986 | 896 | 6 | 19108 | 49 |
LIFR,SLC1A2,AQP4,ATP1A2,GPC5,SLC1A3 |
2.629e-02 | -3.64 | Myometrial Relaxation and Contraction Pathways | WikiPathways | WP289 | 158 | 3 | 5310 | 22 |
ITPR2,RYR3,ADCY2 |
2.631e-02 | -3.64 | DNAAF2 (dynein axonemal assembly factor 2) | protein interactions | 55172 | 98 | 2 | 19454 | 50 |
GPM6A,LSAMP |
2.631e-02 | -3.64 | FRS2 (fibroblast growth factor receptor substrate 2) | protein interactions | 10818 | 98 | 2 | 19454 | 50 |
NTRK2,SORBS1 |
2.631e-02 | -3.64 | MED27 (mediator complex subunit 27) | protein interactions | 9442 | 98 | 2 | 19454 | 50 |
QKI,SOX5 |
2.644e-02 | -3.63 | Doublecortin domain | gene3d domains | 3.10.20.230 | 9 | 1 | 14470 | 43 |
DCLK2 |
2.645e-02 | -3.63 | dermatan sulfate biosynthesis | BIOCYC pathways | HUMAN_PWY-6571 | 12 | 1 | 902 | 2 |
CSGALNACT1 |
2.645e-02 | -3.63 | protein tetramerization | biological process | GO:0051262 | 92 | 2 | 18204 | 50 |
AQP4,RYR3 |
2.666e-02 | -3.62 | PAS_3 | pfam domains | PF08447 | 10 | 1 | 17795 | 48 |
NPAS3 |
2.666e-02 | -3.62 | TCF7L2 (transcription factor 7 like 2) | protein interactions | 6934 | 251 | 3 | 19454 | 50 |
LIFR,CTNNA2,NFIA |
2.668e-02 | -3.62 | PAS_fold_3 | interpro domains | IPR013655 | 10 | 1 | 18521 | 50 |
NPAS3 |
2.668e-02 | -3.62 | Doublecortin_dom_sf | interpro domains | IPR036572 | 10 | 1 | 18521 | 50 |
DCLK2 |
2.668e-02 | -3.62 | MIP_CS | interpro domains | IPR022357 | 10 | 1 | 18521 | 50 |
AQP4 |
2.676e-02 | -3.62 | inorganic cation transmembrane transport | biological process | GO:0098662 | 618 | 5 | 18204 | 50 |
ITPR2,ATP1A2,SLC1A3,GPM6A,RYR3 |
2.680e-02 | -3.62 | ZFHX3 (zinc finger homeobox 3) | protein interactions | 463 | 99 | 2 | 19454 | 50 |
TRPS1,SOX5 |
2.680e-02 | -3.62 | DEFA1 (defensin alpha 1) | protein interactions | 1667 | 99 | 2 | 19454 | 50 |
LIFR,LRIG1 |
2.683e-02 | -3.62 | ATPase-coupled transmembrane transporter activity | molecular function | GO:0042626 | 96 | 2 | 18094 | 48 |
ATP1A2,ATP13A4 |
2.690e-02 | -3.62 | PI3K events in ERBB4 signaling | REACTOME pathways | R-HSA-1250342 | 10 | 1 | 10285 | 28 |
NRG3 |
2.690e-02 | -3.62 | Adenylate cyclase activating pathway | REACTOME pathways | R-HSA-170660 | 10 | 1 | 10285 | 28 |
ADCY2 |
2.693e-02 | -3.61 | behavior | biological process | GO:0007610 | 619 | 5 | 18204 | 50 |
PTPRZ1,ATP1A2,NTRK2,SLC1A3,SLC1A2 |
2.693e-02 | -3.61 | CRX (cone-rod homeobox) | protein interactions | 1406 | 252 | 3 | 19454 | 50 |
NFIA,TRPS1,SOX5 |
2.693e-02 | -3.61 | NCK2 (NCK adaptor protein 2) | protein interactions | 8440 | 252 | 3 | 19454 | 50 |
SORBS1,NTRK2,NHSL1 |
2.706e-02 | -3.61 | GS | smart domains | SM00467 | 7 | 1 | 9717 | 38 |
BMPR1B |
2.706e-02 | -3.61 | PLEC | smart domains | SM00250 | 7 | 1 | 9717 | 38 |
MACF1 |
2.714e-02 | -3.61 | substrate-independent telencephalic tangential interneuron migration | biological process | GO:0021843 | 10 | 1 | 18204 | 50 |
NRG3 |
2.714e-02 | -3.61 | regulation of mesenchymal stem cell differentiation | biological process | GO:2000739 | 10 | 1 | 18204 | 50 |
SOX5 |
2.714e-02 | -3.61 | substrate-independent telencephalic tangential migration | biological process | GO:0021826 | 10 | 1 | 18204 | 50 |
NRG3 |
2.714e-02 | -3.61 | cellular response to brain-derived neurotrophic factor stimulus | biological process | GO:1990416 | 10 | 1 | 18204 | 50 |
NTRK2 |
2.714e-02 | -3.61 | otolith development | biological process | GO:0048840 | 10 | 1 | 18204 | 50 |
LRIG1 |
2.714e-02 | -3.61 | establishment of centrosome localization | biological process | GO:0051660 | 10 | 1 | 18204 | 50 |
PARD3B |
2.714e-02 | -3.61 | positive regulation of lipopolysaccharide-mediated signaling pathway | biological process | GO:0031666 | 10 | 1 | 18204 | 50 |
SASH1 |
2.714e-02 | -3.61 | release of sequestered calcium ion into cytosol by endoplasmic reticulum | biological process | GO:1903514 | 10 | 1 | 18204 | 50 |
RYR3 |
2.714e-02 | -3.61 | retinal rod cell development | biological process | GO:0046548 | 10 | 1 | 18204 | 50 |
NTRK2 |
2.714e-02 | -3.61 | trans-synaptic signaling, modulating synaptic transmission | biological process | GO:0099550 | 10 | 1 | 18204 | 50 |
NTRK2 |
2.714e-02 | -3.61 | cAMP biosynthetic process | biological process | GO:0006171 | 10 | 1 | 18204 | 50 |
ADCY2 |
2.731e-02 | -3.60 | ATP4A (ATPase H+/K+ transporting subunit alpha) | protein interactions | 495 | 100 | 2 | 19454 | 50 |
ATP1A2,GPM6A |
2.733e-02 | -3.60 | cGMP signaling | KEGG pathways | M00694 | 9 | 1 | 7161 | 22 |
PRKG1 |
2.733e-02 | -3.60 | cGMP signaling | KEGG pathways | hsa_M00694 | 9 | 1 | 7161 | 22 |
PRKG1 |
2.737e-02 | -3.60 | pancreas-other-adenoma | COSMIC cancer mutations | pancreas-other-adenoma | 224 | 3 | 16828 | 49 |
CTNND2,PCDH9,BMPR1B |
2.738e-02 | -3.60 | cellular response to chemical stimulus | biological process | GO:0070887 | 2411 | 12 | 18204 | 50 |
AQP4,SLC1A2,ZBTB20,ATP1A2,ITPR2,SORBS1,LIFR,SLC1A3,NTRK2,RYR3,RORA,ADCY2 |
2.756e-02 | -3.59 | muscle contraction | biological process | GO:0006936 | 238 | 3 | 18204 | 50 |
ATP1A2,RYR3,DTNA |
2.758e-02 | -3.59 | Insulin secretion | KEGG pathways | hsa04911 | 85 | 2 | 7161 | 22 |
ATP1A2,ADCY2 |
2.769e-02 | -3.59 | NK-T_cell_lymphoma | COSMIC cancer mutations | NK-T_cell_lymphoma | 225 | 3 | 16828 | 49 |
RFX4,MGAT4C,DTNA |
2.776e-02 | -3.58 | DYNLL2 (dynein light chain LC8-type 2) | protein interactions | 140735 | 255 | 3 | 19454 | 50 |
NFIA,TRPS1,NHSL1 |
2.781e-02 | -3.58 | EVPL (envoplakin) | protein interactions | 2125 | 101 | 2 | 19454 | 50 |
NKAIN3,PPP2R2B |
2.786e-02 | -3.58 | platelet dense tubular network | cellular component | GO:0031094 | 11 | 1 | 19108 | 49 |
ITPR2 |
2.786e-02 | -3.58 | perisynaptic extracellular matrix | cellular component | GO:0098966 | 11 | 1 | 19108 | 49 |
PTPRZ1 |
2.789e-02 | -3.58 | GATA_ZN_FINGER_1 | prosite domains | PS00344 | 8 | 1 | 12186 | 43 |
TRPS1 |
2.789e-02 | -3.58 | HP | prosite domains | PS51089 | 8 | 1 | 12186 | 43 |
ABLIM1 |
2.792e-02 | -3.58 | Cobll1 (Cobl-like 1) | protein interactions | 319876 | 11 | 1 | 19454 | 50 |
ABLIM1 |
2.792e-02 | -3.58 | IL7 (interleukin 7) | protein interactions | 3574 | 11 | 1 | 19454 | 50 |
QKI |
2.792e-02 | -3.58 | Batf3 (basic leucine zipper transcription factor, ATF-like 3) | protein interactions | 381319 | 11 | 1 | 19454 | 50 |
MACF1 |
2.792e-02 | -3.58 | GAL3ST1 (galactose-3-O-sulfotransferase 1) | protein interactions | 9514 | 11 | 1 | 19454 | 50 |
LRIG1 |
2.792e-02 | -3.58 | AQP5 (aquaporin 5) | protein interactions | 362 | 11 | 1 | 19454 | 50 |
ATP1A2 |
2.792e-02 | -3.58 | Wipi2 (WD repeat domain, phosphoinositide interacting 2) | protein interactions | 74781 | 11 | 1 | 19454 | 50 |
MACF1 |
2.792e-02 | -3.58 | DAZ1 (deleted in azoospermia 1) | protein interactions | 1617 | 11 | 1 | 19454 | 50 |
QKI |
2.792e-02 | -3.58 | SYN3 (synapsin III) | protein interactions | 8224 | 11 | 1 | 19454 | 50 |
GPM6A |
2.792e-02 | -3.58 | ADCY5 (adenylate cyclase 5) | protein interactions | 111 | 11 | 1 | 19454 | 50 |
ADCY2 |
2.792e-02 | -3.58 | Gtf2e2 (general transcription factor II E, polypeptide 2 (beta subunit)) | protein interactions | 68153 | 11 | 1 | 19454 | 50 |
NHSL1 |
2.795e-02 | -3.58 | axon development | biological process | GO:0061564 | 420 | 4 | 18204 | 50 |
BMPR1B,PTPRZ1,CTNNA2,PRKG1 |
2.802e-02 | -3.58 | RNA polymerase II transcription regulatory region sequence-specific DNA binding | molecular function | GO:0000977 | 1385 | 8 | 18094 | 48 |
NPAS3,SOX5,GLIS3,RORA,RFX4,TRPS1,ZBTB20,NFIA |
2.807e-02 | -3.57 | cardiac muscle cell differentiation | biological process | GO:0055007 | 95 | 2 | 18204 | 50 |
NEBL,PRKG1 |
2.807e-02 | -3.57 | calcium ion transmembrane import into cytosol | biological process | GO:0097553 | 95 | 2 | 18204 | 50 |
RYR3,ITPR2 |
2.832e-02 | -3.56 | human chr8q12.3 | chromosome location | human chr8q12.3 | 15 | 1 | 26134 | 50 |
NKAIN3 |
2.832e-02 | -3.56 | human chr10p12.31 | chromosome location | human chr10p12.31 | 15 | 1 | 26134 | 50 |
NEBL |
2.832e-02 | -3.56 | MIR7-1 (microRNA 7-1) | protein interactions | 407043 | 102 | 2 | 19454 | 50 |
MSI2,QKI |
2.862e-02 | -3.55 | pleura | COSMIC cancer mutations | pleura | 4914 | 21 | 16828 | 49 |
MAML2,NTRK2,PPP2R2B,DCLK2,FBXL7,LIFR,PITPNC1,MSI2,QKI,SOX5,CTNND2,RORA,NTM,PTPRZ1,TRPS1,ATP13A4,LRIG1,NEBL,BMPR1B,PRKG1,ITPR2 |
2.865e-02 | -3.55 | urinary_tract-bladder-carcinoma | COSMIC cancer mutations | urinary_tract-bladder-carcinoma | 14050 | 46 | 16828 | 49 |
SOX5,ZBTB20,RORA,SASH1,NTM,CSGALNACT1,ATP1A2,LRIG1,RFX4,GPM6A,PPP2R2B,DCLK2,ADCY2,MGAT4C,SORBS1,MACF1,ATP13A4,PRKG1,MAML2,GPC5,CDH20,QKI,SLC1A3,LSAMP,NPAS3,PCDH9,TRPS1,BMPR1B,ITPR2,ABLIM1,NRG3,DTNA,LIFR,NFIA,FBXL7,MSI2,CTNND2,PTPRZ1,RYR3,NEBL,NTRK2,PITPNC1,SLC1A2,PARD3B,SPARCL1,GLIS3 |
2.875e-02 | -3.55 | chiasm | COSMIC cancer mutations | chiasm | 10 | 1 | 16828 | 49 |
QKI |
2.876e-02 | -3.55 | metal ion transport | biological process | GO:0030001 | 630 | 5 | 18204 | 50 |
RYR3,GPM6A,SLC1A3,ATP1A2,ITPR2 |
2.880e-02 | -3.55 | sulfur amino acid transmembrane transporter activity | molecular function | GO:0000099 | 11 | 1 | 18094 | 48 |
SLC1A2 |
2.884e-02 | -3.55 | CSGALNACT2 (chondroitin sulfate N-acetylgalactosaminyltransferase 2) | protein interactions | 55454 | 103 | 2 | 19454 | 50 |
MGAT4C,CSGALNACT1 |
2.884e-02 | -3.55 | RAB6B (RAB6B, member RAS oncogene family) | protein interactions | 51560 | 103 | 2 | 19454 | 50 |
BMPR1B,GPM6A |
2.889e-02 | -3.54 | MARK2 (microtubule affinity regulating kinase 2) | protein interactions | 2011 | 259 | 3 | 19454 | 50 |
PPP2R2B,DTNA,PARD3B |
2.893e-02 | -3.54 | amino acid transmembrane transporter activity | molecular function | GO:0015171 | 100 | 2 | 18094 | 48 |
SLC1A2,SLC1A3 |
2.893e-02 | -3.54 | Intracellular Signalling Through LHCGR Receptor and Luteinizing Hormone/Choriogonadotropin | SMPDB pathways | SMP0000338 | 10 | 1 | 1369 | 4 |
ADCY2 |
2.894e-02 | -3.54 | Ig-like_dom | interpro domains | IPR007110 | 432 | 4 | 18521 | 50 |
NTRK2,LSAMP,LRIG1,NTM |
2.917e-02 | -3.53 | nerve development | biological process | GO:0021675 | 97 | 2 | 18204 | 50 |
LRIG1,SLC1A3 |
2.917e-02 | -3.53 | amino acid transmembrane transport | biological process | GO:0003333 | 97 | 2 | 18204 | 50 |
SLC1A3,SLC1A2 |
2.928e-02 | -3.53 | LRRCT | pfam domains | PF01463 | 11 | 1 | 17795 | 48 |
LRIG1 |
2.931e-02 | -3.53 | Tyr_kinase_rcpt_2_CS | interpro domains | IPR002011 | 11 | 1 | 18521 | 50 |
NTRK2 |
2.968e-02 | -3.52 | intracellular monoatomic cation homeostasis | biological process | GO:0030003 | 428 | 4 | 18204 | 50 |
SLC1A3,ATP13A4,RYR3,ATP1A2 |
2.979e-02 | -3.51 | active transmembrane transporter activity | molecular function | GO:0022804 | 444 | 4 | 18094 | 48 |
SLC1A3,SLC1A2,ATP13A4,ATP1A2 |
2.981e-02 | -3.51 | cellular response to caffeine | biological process | GO:0071313 | 11 | 1 | 18204 | 50 |
RYR3 |
2.981e-02 | -3.51 | polyamine transport | biological process | GO:0015846 | 11 | 1 | 18204 | 50 |
ATP13A4 |
2.981e-02 | -3.51 | antral ovarian follicle growth | biological process | GO:0001547 | 11 | 1 | 18204 | 50 |
BMPR1B |
2.981e-02 | -3.51 | glutamate secretion | biological process | GO:0014047 | 11 | 1 | 18204 | 50 |
NTRK2 |
2.981e-02 | -3.51 | negative regulation of platelet aggregation | biological process | GO:0090331 | 11 | 1 | 18204 | 50 |
PRKG1 |
2.981e-02 | -3.51 | ectodermal placode morphogenesis | biological process | GO:0071697 | 11 | 1 | 18204 | 50 |
NRG3 |
2.981e-02 | -3.51 | negative regulation of neuron migration | biological process | GO:2001223 | 11 | 1 | 18204 | 50 |
NRG3 |
2.981e-02 | -3.51 | intracellular mRNA localization | biological process | GO:0008298 | 11 | 1 | 18204 | 50 |
QKI |
2.981e-02 | -3.51 | physiological cardiac muscle hypertrophy | biological process | GO:0003301 | 11 | 1 | 18204 | 50 |
PRKG1 |
2.981e-02 | -3.51 | pyramidal neuron development | biological process | GO:0021860 | 11 | 1 | 18204 | 50 |
DCLK2 |
2.981e-02 | -3.51 | physiological muscle hypertrophy | biological process | GO:0003298 | 11 | 1 | 18204 | 50 |
PRKG1 |
2.981e-02 | -3.51 | cell growth involved in cardiac muscle cell development | biological process | GO:0061049 | 11 | 1 | 18204 | 50 |
PRKG1 |
2.981e-02 | -3.51 | ectodermal placode formation | biological process | GO:0060788 | 11 | 1 | 18204 | 50 |
NRG3 |
2.981e-02 | -3.51 | establishment or maintenance of transmembrane electrochemical gradient | biological process | GO:0010248 | 11 | 1 | 18204 | 50 |
ATP1A2 |
2.981e-02 | -3.51 | heparin biosynthetic process | biological process | GO:0030210 | 11 | 1 | 18204 | 50 |
CSGALNACT1 |
2.981e-02 | -3.51 | lactone metabolic process | biological process | GO:1901334 | 11 | 1 | 18204 | 50 |
ATP1A2 |
2.981e-02 | -3.51 | L-ascorbic acid metabolic process | biological process | GO:0019852 | 11 | 1 | 18204 | 50 |
ATP1A2 |
2.981e-02 | -3.51 | PPP2CA (protein phosphatase 2 catalytic subunit alpha) | protein interactions | 5515 | 458 | 4 | 19454 | 50 |
CSGALNACT1,BMPR1B,PPP2R2B,NHSL1 |
2.984e-02 | -3.51 | cell motility | biological process | GO:0048870 | 1101 | 7 | 18204 | 50 |
PRKG1,CTNNA2,CDH20,GPC5,NTRK2,GPM6A,NRG3 |
2.999e-02 | -3.51 | regulation of synapse organization | biological process | GO:0050807 | 246 | 3 | 18204 | 50 |
CTNNA2,GPM6A,NTRK2 |
3.028e-02 | -3.50 | bone morphogenesis | biological process | GO:0060349 | 99 | 2 | 18204 | 50 |
CSGALNACT1,BMPR1B |
3.034e-02 | -3.50 | trans-synaptic signaling | biological process | GO:0099537 | 431 | 4 | 18204 | 50 |
NTRK2,SLC1A2,SLC1A3,DTNA |
3.034e-02 | -3.50 | response to wounding | biological process | GO:0009611 | 431 | 4 | 18204 | 50 |
NFIA,SLC1A3,SLC1A2,MACF1 |
3.035e-02 | -3.49 | sodium:potassium-exchanging ATPase complex | cellular component | GO:0005890 | 12 | 1 | 19108 | 49 |
ATP1A2 |
3.035e-02 | -3.49 | synapse-associated extracellular matrix | cellular component | GO:0099535 | 12 | 1 | 19108 | 49 |
PTPRZ1 |
3.042e-02 | -3.49 | IL15 (interleukin 15) | protein interactions | 3600 | 12 | 1 | 19454 | 50 |
LRIG1 |
3.042e-02 | -3.49 | BAMBI (BMP and activin membrane bound inhibitor) | protein interactions | 25805 | 12 | 1 | 19454 | 50 |
BMPR1B |
3.042e-02 | -3.49 | NTF4 (neurotrophin 4) | protein interactions | 4909 | 12 | 1 | 19454 | 50 |
NTRK2 |
3.042e-02 | -3.49 | ART4 (ADP-ribosyltransferase 4 (inactive) (Dombrock blood group)) | protein interactions | 420 | 12 | 1 | 19454 | 50 |
GPM6A |
3.042e-02 | -3.49 | CTF1 (cardiotrophin 1) | protein interactions | 1489 | 12 | 1 | 19454 | 50 |
LIFR |
3.079e-02 | -3.48 | inorganic ion homeostasis | biological process | GO:0098771 | 433 | 4 | 18204 | 50 |
SLC1A3,ATP13A4,RYR3,ATP1A2 |
3.087e-02 | -3.48 | VHP | smart domains | SM00153 | 8 | 1 | 9717 | 38 |
ABLIM1 |
3.114e-02 | -3.47 | Leu-rich_rpt | interpro domains | IPR001611 | 254 | 3 | 18521 | 50 |
LRIG1,FBXL7,NTRK2 |
3.124e-02 | -3.47 | LIM | smart domains | SM00132 | 71 | 2 | 9717 | 38 |
NEBL,ABLIM1 |
3.129e-02 | -3.46 | mRNA surveillance pathway | KEGG pathways | ko03015 | 91 | 2 | 7161 | 22 |
PPP2R2B,MSI2 |
3.129e-02 | -3.46 | mRNA surveillance pathway | KEGG pathways | hsa03015 | 91 | 2 | 7161 | 22 |
MSI2,PPP2R2B |
3.132e-02 | -3.46 | RFX_DBD | prosite domains | PS51526 | 9 | 1 | 12186 | 43 |
RFX4 |
3.132e-02 | -3.46 | DC | prosite domains | PS50309 | 9 | 1 | 12186 | 43 |
DCLK2 |
3.138e-02 | -3.46 | adenylate cyclase binding | molecular function | GO:0008179 | 12 | 1 | 18094 | 48 |
ADCY2 |
3.138e-02 | -3.46 | inositol 1,4,5 trisphosphate binding | molecular function | GO:0070679 | 12 | 1 | 18094 | 48 |
ITPR2 |
3.142e-02 | -3.46 | regulation of glucose metabolic process | biological process | GO:0010906 | 101 | 2 | 18204 | 50 |
SORBS1,RORA |
3.142e-02 | -3.46 | regulation of carbohydrate biosynthetic process | biological process | GO:0043255 | 101 | 2 | 18204 | 50 |
PRKG1,SORBS1 |
3.147e-02 | -3.46 | CLASP1 (cytoplasmic linker associated protein 1) | protein interactions | 23332 | 108 | 2 | 19454 | 50 |
DCLK2,MACF1 |
3.147e-02 | -3.46 | EN1 (engrailed homeobox 1) | protein interactions | 2019 | 108 | 2 | 19454 | 50 |
TRPS1,NFIA |
3.147e-02 | -3.46 | PAX8 (paired box 8) | protein interactions | 7849 | 108 | 2 | 19454 | 50 |
NFIA,TRPS1 |
3.147e-02 | -3.46 | FKBP1A (FKBP prolyl isomerase 1A) | protein interactions | 2280 | 108 | 2 | 19454 | 50 |
MSI2,RYR3 |
3.147e-02 | -3.46 | DSG4 (desmoglein 4) | protein interactions | 147409 | 108 | 2 | 19454 | 50 |
SPARCL1,CSGALNACT1 |
3.151e-02 | -3.46 | VCL (vinculin) | protein interactions | 7414 | 268 | 3 | 19454 | 50 |
NEBL,SORBS1,MACF1 |
3.157e-02 | -3.46 | calcium ion transport | biological process | GO:0006816 | 251 | 3 | 18204 | 50 |
ITPR2,RYR3,GPM6A |
3.169e-02 | -3.45 | intracellular monoatomic ion homeostasis | biological process | GO:0006873 | 437 | 4 | 18204 | 50 |
ATP1A2,ATP13A4,RYR3,SLC1A3 |
3.171e-02 | -3.45 | GATAZNFINGER | prints domains | PR00619 | 8 | 1 | 5227 | 21 |
TRPS1 |
3.179e-02 | -3.45 | NAD+ Signalling and Aging | SMPDB pathways | SMP0084271 | 11 | 1 | 1369 | 4 |
RORA |
3.189e-02 | -3.45 | regulation of synapse structure or activity | biological process | GO:0050803 | 252 | 3 | 18204 | 50 |
CTNNA2,NTRK2,GPM6A |
3.190e-02 | -3.45 | MH1 | pfam domains | PF03165 | 12 | 1 | 17795 | 48 |
NFIA |
3.192e-02 | -3.44 | GnRH signaling pathway | KEGG pathways | ko04912 | 92 | 2 | 7161 | 22 |
ADCY2,ITPR2 |
3.192e-02 | -3.44 | GnRH signaling pathway | KEGG pathways | hsa04912 | 92 | 2 | 7161 | 22 |
ITPR2,ADCY2 |
3.193e-02 | -3.44 | TGFB_receptor | interpro domains | IPR000333 | 12 | 1 | 18521 | 50 |
BMPR1B |
3.193e-02 | -3.44 | MAD_homology1_Dwarfin-type | interpro domains | IPR003619 | 12 | 1 | 18521 | 50 |
NFIA |
3.200e-02 | -3.44 | CLSTN1 (calsyntenin 1) | protein interactions | 22883 | 109 | 2 | 19454 | 50 |
SLC1A3,MGAT4C |
3.200e-02 | -3.44 | MIR34B (microRNA 34b) | protein interactions | 407041 | 109 | 2 | 19454 | 50 |
QKI,MSI2 |
3.204e-02 | -3.44 | human chr9q21.33 | chromosome location | human chr9q21.33 | 17 | 1 | 26134 | 50 |
NTRK2 |
3.207e-02 | -3.44 | bile_duct | COSMIC cancer mutations | bile_duct | 15095 | 48 | 16828 | 49 |
SLC1A2,PARD3B,GLIS3,SPARCL1,PITPNC1,NTRK2,RYR3,NEBL,PTPRZ1,CTNND2,MSI2,LIFR,NFIA,FBXL7,DTNA,NHSL1,ABLIM1,NRG3,BMPR1B,ITPR2,TRPS1,SLC1A3,LSAMP,NPAS3,PCDH9,GPC5,QKI,CDH20,MAML2,AQP4,PRKG1,MACF1,ATP13A4,SORBS1,MGAT4C,DCLK2,ADCY2,RFX4,PPP2R2B,GPM6A,CSGALNACT1,ATP1A2,LRIG1,SASH1,NTM,SOX5,ZBTB20,RORA |
3.207e-02 | -3.44 | biliary_tract-bile_duct-carcinoma-adenocarcinoma | COSMIC cancer mutations | biliary_tract-bile_duct-carcinoma-adenocarcinoma | 15095 | 48 | 16828 | 49 |
CTNND2,PTPRZ1,RYR3,NEBL,NTRK2,PITPNC1,SPARCL1,GLIS3,PARD3B,SLC1A2,NPAS3,PCDH9,SLC1A3,LSAMP,TRPS1,ITPR2,BMPR1B,ABLIM1,NRG3,NHSL1,DTNA,NFIA,LIFR,FBXL7,MSI2,SORBS1,ATP13A4,MACF1,PRKG1,MAML2,AQP4,QKI,CDH20,GPC5,RORA,ZBTB20,SOX5,NTM,SASH1,LRIG1,CSGALNACT1,ATP1A2,PPP2R2B,GPM6A,RFX4,DCLK2,ADCY2,MGAT4C |
3.220e-02 | -3.44 | Defective EXT1 causes exostoses 1, TRPS2 and CHDS | REACTOME pathways | R-HSA-3656253 | 12 | 1 | 10285 | 28 |
GPC5 |
3.220e-02 | -3.44 | Defective EXT2 causes exostoses 2 | REACTOME pathways | R-HSA-3656237 | 12 | 1 | 10285 | 28 |
GPC5 |
3.248e-02 | -3.43 | sulfur amino acid transport | biological process | GO:0000101 | 12 | 1 | 18204 | 50 |
SLC1A2 |
3.248e-02 | -3.43 | microglia differentiation | biological process | GO:0014004 | 12 | 1 | 18204 | 50 |
QKI |
3.248e-02 | -3.43 | mammalian oogenesis stage | biological process | GO:0022605 | 12 | 1 | 18204 | 50 |
BMPR1B |
3.248e-02 | -3.43 | dermatan sulfate proteoglycan metabolic process | biological process | GO:0050655 | 12 | 1 | 18204 | 50 |
CSGALNACT1 |
3.248e-02 | -3.43 | auditory behavior | biological process | GO:0031223 | 12 | 1 | 18204 | 50 |
SLC1A3 |
3.248e-02 | -3.43 | negative regulation of smooth muscle contraction | biological process | GO:0045986 | 12 | 1 | 18204 | 50 |
PRKG1 |
3.248e-02 | -3.43 | positive regulation of extrinsic apoptotic signaling pathway via death domain receptors | biological process | GO:1902043 | 12 | 1 | 18204 | 50 |
BMPR1B |
3.250e-02 | -3.43 | DNA-binding transcription repressor activity, RNA polymerase II-specific | molecular function | GO:0001227 | 263 | 3 | 18094 | 48 |
TRPS1,GLIS3,ZBTB20 |
3.254e-02 | -3.43 | LZTR1 (leucine zipper like post translational regulator 1) | protein interactions | 8216 | 110 | 2 | 19454 | 50 |
BMPR1B,PARD3B |
3.257e-02 | -3.42 | cerebellum development | biological process | GO:0021549 | 103 | 2 | 18204 | 50 |
RORA,PRKG1 |
3.264e-02 | -3.42 | functioning | COSMIC cancer mutations | functioning | 1803 | 10 | 16828 | 49 |
SLC1A2,PTPRZ1,PCDH9,NHSL1,MAML2,ZBTB20,RFX4,NRG3,SOX5,NTRK2 |
3.264e-02 | -3.42 | adrenal_gland-adrenal_gland-adrenal_cortical_carcinoma-functioning | COSMIC cancer mutations | adrenal_gland-adrenal_gland-adrenal_cortical_carcinoma-functioning | 1803 | 10 | 16828 | 49 |
SLC1A2,NTRK2,RFX4,NRG3,SOX5,ZBTB20,MAML2,NHSL1,PTPRZ1,PCDH9 |
3.270e-02 | -3.42 | nervous system process | biological process | GO:0050877 | 1376 | 8 | 18204 | 50 |
PTPRZ1,CTNNA2,ATP1A2,NTRK2,SLC1A3,AQP4,ABLIM1,LRIG1 |
3.271e-02 | -3.42 | RDX (radixin) | protein interactions | 5962 | 272 | 3 | 19454 | 50 |
ABLIM1,NEBL,MACF1 |
3.276e-02 | -3.42 | steroid binding | molecular function | GO:0005496 | 107 | 2 | 18094 | 48 |
ATP1A2,RORA |
3.281e-02 | -3.42 | distal axon | cellular component | GO:0150034 | 273 | 3 | 19108 | 49 |
PCDH9,NTRK2,GPM6A |
3.291e-02 | -3.41 | RAB3C (RAB3C, member RAS oncogene family) | protein interactions | 115827 | 13 | 1 | 19454 | 50 |
GPM6A |
3.291e-02 | -3.41 | SPINK5 (serine peptidase inhibitor Kazal type 5) | protein interactions | 11005 | 13 | 1 | 19454 | 50 |
CSGALNACT1 |
3.291e-02 | -3.41 | TBCC (tubulin folding cofactor C) | protein interactions | 6903 | 13 | 1 | 19454 | 50 |
NTM |
3.291e-02 | -3.41 | PCDHA2 (protocadherin alpha 2) | protein interactions | 56146 | 13 | 1 | 19454 | 50 |
NFIA |
3.291e-02 | -3.41 | Rbm47 (RNA binding motif protein 47) | protein interactions | 245945 | 13 | 1 | 19454 | 50 |
QKI |
3.300e-02 | -3.41 | dermatan sulfate biosynthesis | BIOCYC pathways | META_PWY-6571 | 15 | 1 | 902 | 2 |
CSGALNACT1 |
3.310e-02 | -3.41 | bladder | COSMIC cancer mutations | bladder | 14112 | 46 | 16828 | 49 |
LRIG1,ATP1A2,CSGALNACT1,NTM,SASH1,RORA,ZBTB20,SOX5,MGAT4C,ADCY2,DCLK2,PPP2R2B,GPM6A,RFX4,PRKG1,ATP13A4,MACF1,SORBS1,CDH20,QKI,GPC5,MAML2,ITPR2,BMPR1B,TRPS1,PCDH9,NPAS3,SLC1A3,LSAMP,MSI2,FBXL7,LIFR,NFIA,DTNA,NRG3,ABLIM1,NEBL,RYR3,PTPRZ1,CTNND2,SPARCL1,PARD3B,GLIS3,SLC1A2,PITPNC1,NTRK2 |
3.310e-02 | -3.41 | urinary_tract | COSMIC cancer mutations | urinary_tract | 14112 | 46 | 16828 | 49 |
MACF1,ATP13A4,PRKG1,SORBS1,GPC5,QKI,CDH20,MAML2,ATP1A2,CSGALNACT1,LRIG1,SOX5,ZBTB20,RORA,SASH1,NTM,MGAT4C,RFX4,PPP2R2B,GPM6A,ADCY2,DCLK2,NEBL,RYR3,CTNND2,PTPRZ1,PITPNC1,SLC1A2,PARD3B,GLIS3,SPARCL1,NTRK2,TRPS1,BMPR1B,ITPR2,SLC1A3,LSAMP,NPAS3,PCDH9,FBXL7,NFIA,LIFR,MSI2,NRG3,ABLIM1,DTNA |
3.315e-02 | -3.41 | regulation of steroid metabolic process | biological process | GO:0019218 | 104 | 2 | 18204 | 50 |
RORA,PRKG1 |
3.318e-02 | -3.41 | protein complex oligomerization | biological process | GO:0051259 | 256 | 3 | 18204 | 50 |
RYR3,AQP4,SLC1A2 |
3.363e-02 | -3.39 | HMGCS1 (3-hydroxy-3-methylglutaryl-CoA synthase 1) | protein interactions | 3157 | 112 | 2 | 19454 | 50 |
PPP2R2B,GPM6A |
3.363e-02 | -3.39 | CEP170P1 (centrosomal protein 170 pseudogene 1) | protein interactions | 645455 | 112 | 2 | 19454 | 50 |
MACF1,TRPS1 |
3.368e-02 | -3.39 | large_intestine-rectum-adenoma | COSMIC cancer mutations | large_intestine-rectum-adenoma | 99 | 2 | 16828 | 49 |
LIFR,NTRK2 |
3.373e-02 | -3.39 | cellular response to alcohol | biological process | GO:0097306 | 105 | 2 | 18204 | 50 |
ADCY2,ITPR2 |
3.387e-02 | -3.39 | skin-arm-malignant_melanoma | COSMIC cancer mutations | skin-arm-malignant_melanoma | 1308 | 8 | 16828 | 49 |
ATP1A2,TRPS1,MACF1,PARD3B,ZBTB20,NPAS3,NTM,SORBS1 |
3.389e-02 | -3.38 | human chr7q31.32 | chromosome location | human chr7q31.32 | 18 | 1 | 26134 | 50 |
PTPRZ1 |
3.389e-02 | -3.38 | human chr18q21.33 | chromosome location | human chr18q21.33 | 18 | 1 | 26134 | 50 |
CDH20 |
3.395e-02 | -3.38 | transforming growth factor beta receptor activity | molecular function | GO:0005024 | 13 | 1 | 18094 | 48 |
BMPR1B |
3.395e-02 | -3.38 | potassium ion binding | molecular function | GO:0030955 | 13 | 1 | 18094 | 48 |
ATP1A2 |
3.400e-02 | -3.38 | calcium ion binding | molecular function | GO:0005509 | 683 | 5 | 18094 | 48 |
ITPR2,RYR3,MACF1,PCDH9,SPARCL1 |
3.400e-02 | -3.38 | Transport of inorganic cations/anions and amino acids/oligopeptides | REACTOME pathways | R-HSA-425393 | 107 | 2 | 10285 | 28 |
SLC1A2,SLC1A3 |
3.418e-02 | -3.38 | haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-acute_lymphoblastic_leukaemia | COSMIC cancer mutations | haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-acute_lymphoblastic_leukaemia | 2081 | 11 | 16828 | 49 |
ATP1A2,TRPS1,BMPR1B,PRKG1,SOX5,PTPRZ1,NFIA,NTRK2,DCLK2,ADCY2,DTNA |
3.425e-02 | -3.37 | signal transduction | biological process | GO:0007165 | 4637 | 19 | 18204 | 50 |
ATP1A2,CTNND2,SORBS1,ITPR2,NFIA,MAML2,NRG3,RYR3,NTRK2,LIFR,PITPNC1,MACF1,SPARCL1,DCLK2,BMPR1B,ADCY2,RORA,PRKG1,DTNA |
3.425e-02 | -3.37 | ZDHHC17 (zinc finger DHHC-type palmitoyltransferase 17) | protein interactions | 23390 | 277 | 3 | 19454 | 50 |
SLC1A3,GPM6A,NEBL |
3.440e-02 | -3.37 | central_nervous_system-fourth_ventricle-glioma-astrocytoma_Grade_I | COSMIC cancer mutations | central_nervous_system-fourth_ventricle-glioma-astrocytoma_Grade_I | 12 | 1 | 16828 | 49 |
QKI |
3.440e-02 | -3.37 | DNA-binding transcription factor activity | molecular function | GO:0003700 | 1441 | 8 | 18094 | 48 |
NFIA,RORA,ZBTB20,RFX4,TRPS1,SOX5,NPAS3,GLIS3 |
3.459e-02 | -3.36 | plasma membrane raft | cellular component | GO:0044853 | 114 | 2 | 19108 | 49 |
SORBS1,ATP1A2 |
3.459e-02 | -3.36 | small molecule binding | molecular function | GO:0036094 | 6197 | 23 | 18094 | 48 |
GLIS3,CSGALNACT1,SLC1A3,DCLK2,PRKG1,MGAT4C,SLC1A2,PCDH9,RORA,PITPNC1,TRPS1,ITPR2,BMPR1B,ABLIM1,RYR3,DTNA,ATP1A2,SPARCL1,ADCY2,ATP13A4,MACF1,ZBTB20,NTRK2 |
3.464e-02 | -3.36 | Lactose Degradation | SMPDB pathways | SMP0000457 | 12 | 1 | 1369 | 4 |
ATP1A2 |
3.464e-02 | -3.36 | Lactose Intolerance | SMPDB pathways | SMP0000458 | 12 | 1 | 1369 | 4 |
ATP1A2 |
3.466e-02 | -3.36 | FOLN | smart domains | SM00274 | 9 | 1 | 9717 | 38 |
SPARCL1 |
3.466e-02 | -3.36 | DCX | smart domains | SM00537 | 9 | 1 | 9717 | 38 |
DCLK2 |
3.474e-02 | -3.36 | MIP | prosite domains | PS00221 | 10 | 1 | 12186 | 43 |
AQP4 |
3.484e-02 | -3.36 | ERBB2 Activates PTK6 Signaling | REACTOME pathways | R-HSA-8847993 | 13 | 1 | 10285 | 28 |
NRG3 |
3.484e-02 | -3.36 | NOTCH2 intracellular domain regulates transcription | REACTOME pathways | R-HSA-2197563 | 13 | 1 | 10285 | 28 |
MAML2 |
3.484e-02 | -3.36 | Passive transport by Aquaporins | REACTOME pathways | R-HSA-432047 | 13 | 1 | 10285 | 28 |
AQP4 |
3.484e-02 | -3.36 | CLEC7A (Dectin-1) induces NFAT activation | REACTOME pathways | R-HSA-5607763 | 13 | 1 | 10285 | 28 |
ITPR2 |
3.484e-02 | -3.36 | Notch-HLH transcription pathway | REACTOME pathways | R-HSA-350054 | 13 | 1 | 10285 | 28 |
MAML2 |
3.484e-02 | -3.36 | cell-cell adhesion via plasma-membrane adhesion molecules | biological process | GO:0098742 | 261 | 3 | 18204 | 50 |
PCDH9,SPARCL1,CDH20 |
3.493e-02 | -3.35 | Ion_trans | pfam domains | PF00520 | 109 | 2 | 17795 | 48 |
RYR3,ITPR2 |
3.496e-02 | -3.35 | response to organic substance | biological process | GO:0010033 | 2498 | 12 | 18204 | 50 |
ATP1A2,ZBTB20,AQP4,SLC1A2,ITPR2,SORBS1,NTRK2,SLC1A3,RYR3,LIFR,ADCY2,RORA |
3.500e-02 | -3.35 | Ion_trans_dom | interpro domains | IPR005821 | 109 | 2 | 18521 | 50 |
ITPR2,RYR3 |
3.500e-02 | -3.35 | Cadherin_CS | interpro domains | IPR020894 | 109 | 2 | 18521 | 50 |
PCDH9,CDH20 |
3.510e-02 | -3.35 | Alpha-catenin/vinculin-like | gene3d domains | 1.20.120.230 | 12 | 1 | 14470 | 43 |
CTNNA2 |
3.514e-02 | -3.35 | prepulse inhibition | biological process | GO:0060134 | 13 | 1 | 18204 | 50 |
CTNNA2 |
3.514e-02 | -3.35 | negative regulation of cytosolic calcium ion concentration | biological process | GO:0051481 | 13 | 1 | 18204 | 50 |
ATP1A2 |
3.514e-02 | -3.35 | negative regulation of homotypic cell-cell adhesion | biological process | GO:0034111 | 13 | 1 | 18204 | 50 |
PRKG1 |
3.514e-02 | -3.35 | regulation of respiratory gaseous exchange by nervous system process | biological process | GO:0002087 | 13 | 1 | 18204 | 50 |
ATP1A2 |
3.514e-02 | -3.35 | cerebellar Purkinje cell differentiation | biological process | GO:0021702 | 13 | 1 | 18204 | 50 |
RORA |
3.514e-02 | -3.35 | ectodermal placode development | biological process | GO:0071696 | 13 | 1 | 18204 | 50 |
NRG3 |
3.514e-02 | -3.35 | T-helper 17 cell differentiation | biological process | GO:0072539 | 13 | 1 | 18204 | 50 |
RORA |
3.514e-02 | -3.35 | glial cell fate commitment | biological process | GO:0021781 | 13 | 1 | 18204 | 50 |
NFIA |
3.518e-02 | -3.35 | chondroitin sulfate biosynthesis | BIOCYC pathways | HUMAN_PWY-6569 | 16 | 1 | 902 | 2 |
CSGALNACT1 |
3.518e-02 | -3.35 | Inflammatory mediator regulation of TRP channels | KEGG pathways | ko04750 | 97 | 2 | 7161 | 22 |
ITPR2,ADCY2 |
3.518e-02 | -3.35 | Inflammatory mediator regulation of TRP channels | KEGG pathways | hsa04750 | 97 | 2 | 7161 | 22 |
ITPR2,ADCY2 |
3.527e-02 | -3.34 | ACTB (actin beta) | protein interactions | 60 | 958 | 6 | 19454 | 50 |
MACF1,NHSL1,DTNA,SORBS1,ABLIM1,NEBL |
3.529e-02 | -3.34 | cellular component organization | biological process | GO:0016043 | 5636 | 22 | 18204 | 50 |
SORBS1,CSGALNACT1,CDH20,NFIA,CTNND2,SLC1A2,AQP4,CTNNA2,MACF1,RFX4,SPARCL1,DCLK2,BMPR1B,PARD3B,PRKG1,NEBL,NRG3,RYR3,ABLIM1,GPM6A,PITPNC1,PTPRZ1 |
3.530e-02 | -3.34 | TBXT (T-box transcription factor T) | protein interactions | 6862 | 115 | 2 | 19454 | 50 |
NFIA,TRPS1 |
3.530e-02 | -3.34 | SMAD7 (SMAD family member 7) | protein interactions | 4092 | 115 | 2 | 19454 | 50 |
SOX5,BMPR1B |
3.538e-02 | -3.34 | DNA-binding transcription repressor activity | molecular function | GO:0001217 | 272 | 3 | 18094 | 48 |
GLIS3,TRPS1,ZBTB20 |
3.540e-02 | -3.34 | SPRR2D (small proline rich protein 2D) | protein interactions | 6703 | 14 | 1 | 19454 | 50 |
PPP2R2B |
3.540e-02 | -3.34 | DACT2 (dishevelled binding antagonist of beta catenin 2) | protein interactions | 168002 | 14 | 1 | 19454 | 50 |
ZBTB20 |
3.540e-02 | -3.34 | GAGE1 (G antigen 1) | protein interactions | 2543 | 14 | 1 | 19454 | 50 |
PRKG1 |
3.540e-02 | -3.34 | Asap1 (ArfGAP with SH3 domain, ankyrin repeat and PH domain1) | protein interactions | 13196 | 14 | 1 | 19454 | 50 |
MACF1 |
3.540e-02 | -3.34 | FCGBP (Fc gamma binding protein) | protein interactions | 8857 | 14 | 1 | 19454 | 50 |
PPP2R2B |
3.540e-02 | -3.34 | MB (myoglobin) | protein interactions | 4151 | 14 | 1 | 19454 | 50 |
MAML2 |
3.540e-02 | -3.34 | JMJD7-PLA2G4B (JMJD7-PLA2G4B readthrough) | protein interactions | 8681 | 14 | 1 | 19454 | 50 |
PPP2R2B |
3.540e-02 | -3.34 | RHEBL1 (RHEB like 1) | protein interactions | 121268 | 14 | 1 | 19454 | 50 |
BMPR1B |
3.540e-02 | -3.34 | SLC1A2 (solute carrier family 1 member 2) | protein interactions | 6506 | 14 | 1 | 19454 | 50 |
SLC1A2 |
3.540e-02 | -3.34 | PLXNA4 (plexin A4) | protein interactions | 91584 | 14 | 1 | 19454 | 50 |
GPM6A |
3.540e-02 | -3.34 | Nedd4 (neural precursor cell expressed, developmentally down-regulated 4) | protein interactions | 17999 | 14 | 1 | 19454 | 50 |
GLIS3 |
3.558e-02 | -3.34 | LYN (LYN proto-oncogene, Src family tyrosine kinase) | protein interactions | 4067 | 713 | 5 | 19454 | 50 |
MSI2,ABLIM1,MACF1,SLC1A3,DTNA |
3.574e-02 | -3.33 | human chr6q24.1 | chromosome location | human chr6q24.1 | 19 | 1 | 26134 | 50 |
NHSL1 |
3.574e-02 | -3.33 | human chr5p15.2 | chromosome location | human chr5p15.2 | 19 | 1 | 26134 | 50 |
CTNND2 |
3.574e-02 | -3.33 | human chr11q25 | chromosome location | human chr11q25 | 19 | 1 | 26134 | 50 |
NTM |
3.585e-02 | -3.33 | Estrogen signaling pathway | KEGG pathways | ko04915 | 98 | 2 | 7161 | 22 |
ADCY2,ITPR2 |
3.585e-02 | -3.33 | Estrogen signaling pathway | KEGG pathways | hsa04915 | 98 | 2 | 7161 | 22 |
ADCY2,ITPR2 |
3.610e-02 | -3.32 | oesophagus-lower_third-carcinoma-squamous_cell_carcinoma | COSMIC cancer mutations | oesophagus-lower_third-carcinoma-squamous_cell_carcinoma | 3507 | 16 | 16828 | 49 |
PRKG1,MACF1,ATP1A2,RYR3,LRIG1,SASH1,PCDH9,NPAS3,PTPRZ1,ZBTB20,CTNND2,GPC5,PARD3B,LIFR,ADCY2,DCLK2 |
3.612e-02 | -3.32 | kidney-carcinoma-chromophobe_renal_cell_carcinoma | COSMIC cancer mutations | kidney-carcinoma-chromophobe_renal_cell_carcinoma | 430 | 4 | 16828 | 49 |
NTRK2,PRKG1,BMPR1B,DCLK2 |
3.612e-02 | -3.32 | chromophobe_renal_cell_carcinoma | COSMIC cancer mutations | chromophobe_renal_cell_carcinoma | 430 | 4 | 16828 | 49 |
DCLK2,BMPR1B,PRKG1,NTRK2 |
3.617e-02 | -3.32 | small_intestine | COSMIC cancer mutations | small_intestine | 250 | 3 | 16828 | 49 |
MGAT4C,CSGALNACT1,MACF1 |
3.621e-02 | -3.32 | regulation of nervous system development | biological process | GO:0051960 | 456 | 4 | 18204 | 50 |
PTPRZ1,NTRK2,QKI,MACF1 |
3.636e-02 | -3.31 | Integration of energy metabolism | REACTOME pathways | R-HSA-163685 | 111 | 2 | 10285 | 28 |
ITPR2,ADCY2 |
3.642e-02 | -3.31 | ELK3 (ETS transcription factor ELK3) | protein interactions | 2004 | 117 | 2 | 19454 | 50 |
TRPS1,NFIA |
3.652e-02 | -3.31 | microtubule minus-end binding | molecular function | GO:0051011 | 14 | 1 | 18094 | 48 |
MACF1 |
3.670e-02 | -3.31 | phosphatidylinositol binding | molecular function | GO:0035091 | 276 | 3 | 18094 | 48 |
PITPNC1,PARD3B,ITPR2 |
3.670e-02 | -3.30 | Cadherin | pfam domains | PF00028 | 112 | 2 | 17795 | 48 |
CDH20,PCDH9 |
3.670e-02 | -3.30 | positive regulation of cell development | biological process | GO:0010720 | 458 | 4 | 18204 | 50 |
PTPRZ1,NTRK2,MACF1,QKI |
3.684e-02 | -3.30 | positive regulation of cell differentiation | biological process | GO:0045597 | 906 | 6 | 18204 | 50 |
PTPRZ1,MACF1,QKI,SOX5,NTRK2,BMPR1B |
3.695e-02 | -3.30 | synaptic signaling | biological process | GO:0099536 | 459 | 4 | 18204 | 50 |
NTRK2,SLC1A2,SLC1A3,DTNA |
3.699e-02 | -3.30 | VSIG8 (V-set and immunoglobulin domain containing 8) | protein interactions | 391123 | 118 | 2 | 19454 | 50 |
CSGALNACT1,SPARCL1 |
3.702e-02 | -3.30 | arm | COSMIC cancer mutations | arm | 1331 | 8 | 16828 | 49 |
ATP1A2,MACF1,TRPS1,PARD3B,ZBTB20,SORBS1,NPAS3,NTM |
3.712e-02 | -3.29 | GATA | pfam domains | PF00320 | 14 | 1 | 17795 | 48 |
TRPS1 |
3.712e-02 | -3.29 | MIP | pfam domains | PF00230 | 14 | 1 | 17795 | 48 |
AQP4 |
3.715e-02 | -3.29 | MIP | interpro domains | IPR000425 | 14 | 1 | 18521 | 50 |
AQP4 |
3.715e-02 | -3.29 | Aquaporin-like | interpro domains | IPR023271 | 14 | 1 | 18521 | 50 |
AQP4 |
3.721e-02 | -3.29 | central_nervous_system-hypothalamus-glioma-astrocytoma_Grade_I | COSMIC cancer mutations | central_nervous_system-hypothalamus-glioma-astrocytoma_Grade_I | 13 | 1 | 16828 | 49 |
QKI |
3.747e-02 | -3.28 | DCC mediated attractive signaling | REACTOME pathways | R-HSA-418885 | 14 | 1 | 10285 | 28 |
ABLIM1 |
3.747e-02 | -3.28 | SHC1 events in ERBB4 signaling | REACTOME pathways | R-HSA-1250347 | 14 | 1 | 10285 | 28 |
NRG3 |
3.749e-02 | -3.28 | Trehalose Degradation | SMPDB pathways | SMP0000467 | 13 | 1 | 1369 | 4 |
ATP1A2 |
3.756e-02 | -3.28 | RBM7 (RNA binding motif protein 7) | protein interactions | 10179 | 119 | 2 | 19454 | 50 |
PPP2R2B,QKI |
3.779e-02 | -3.28 | cellular response to ethanol | biological process | GO:0071361 | 14 | 1 | 18204 | 50 |
ITPR2 |
3.779e-02 | -3.28 | glutathione biosynthetic process | biological process | GO:0006750 | 14 | 1 | 18204 | 50 |
SLC1A2 |
3.779e-02 | -3.28 | response to forskolin | biological process | GO:1904321 | 14 | 1 | 18204 | 50 |
ADCY2 |
3.779e-02 | -3.28 | cellular response to purine-containing compound | biological process | GO:0071415 | 14 | 1 | 18204 | 50 |
RYR3 |
3.779e-02 | -3.28 | sodium ion export across plasma membrane | biological process | GO:0036376 | 14 | 1 | 18204 | 50 |
ATP1A2 |
3.779e-02 | -3.28 | cellular response to forskolin | biological process | GO:1904322 | 14 | 1 | 18204 | 50 |
ADCY2 |
3.779e-02 | -3.28 | relaxation of cardiac muscle | biological process | GO:0055119 | 14 | 1 | 18204 | 50 |
ATP1A2 |
3.779e-02 | -3.28 | negative regulation of sodium ion transmembrane transporter activity | biological process | GO:2000650 | 14 | 1 | 18204 | 50 |
ATP1A2 |
3.779e-02 | -3.28 | cerebrospinal fluid circulation | biological process | GO:0090660 | 14 | 1 | 18204 | 50 |
AQP4 |
3.779e-02 | -3.28 | regulation of protein K63-linked ubiquitination | biological process | GO:1900044 | 14 | 1 | 18204 | 50 |
SASH1 |
3.779e-02 | -3.28 | mechanosensory behavior | biological process | GO:0007638 | 14 | 1 | 18204 | 50 |
SLC1A3 |
3.780e-02 | -3.28 | axolemma | cellular component | GO:0030673 | 15 | 1 | 19108 | 49 |
SLC1A2 |
3.788e-02 | -3.27 | NPR1 (natriuretic peptide receptor 1) | protein interactions | 4881 | 15 | 1 | 19454 | 50 |
PRKG1 |
3.788e-02 | -3.27 | XIRP1 (xin actin binding repeat containing 1) | protein interactions | 165904 | 15 | 1 | 19454 | 50 |
NEBL |
3.788e-02 | -3.27 | TESPA1 (thymocyte expressed, positive selection associated 1) | protein interactions | 9840 | 15 | 1 | 19454 | 50 |
ITPR2 |
3.788e-02 | -3.27 | IGSF1 (immunoglobulin superfamily member 1) | protein interactions | 3547 | 15 | 1 | 19454 | 50 |
BMPR1B |
3.788e-02 | -3.27 | PCSK1N (proprotein convertase subtilisin/kexin type 1 inhibitor) | protein interactions | 27344 | 15 | 1 | 19454 | 50 |
MGAT4C |
3.788e-02 | -3.27 | TAFA5 (TAFA chemokine like family member 5) | protein interactions | 25817 | 15 | 1 | 19454 | 50 |
NEBL |
3.788e-02 | -3.27 | Retrograde endocannabinoid signaling | KEGG pathways | hsa04723 | 101 | 2 | 7161 | 22 |
ADCY2,ITPR2 |
3.788e-02 | -3.27 | Retrograde endocannabinoid signaling | KEGG pathways | ko04723 | 101 | 2 | 7161 | 22 |
ITPR2,ADCY2 |
3.794e-02 | -3.27 | rhythmic process | biological process | GO:0048511 | 270 | 3 | 18204 | 50 |
NTRK2,BMPR1B,RORA |
3.794e-02 | -3.27 | regulation of gliogenesis | biological process | GO:0014013 | 112 | 2 | 18204 | 50 |
PTPRZ1,QKI |
3.798e-02 | -3.27 | Cadherin-like_dom | interpro domains | IPR002126 | 114 | 2 | 18521 | 50 |
PCDH9,CDH20 |
3.802e-02 | -3.27 | OCLN (occludin) | protein interactions | 100506658 | 495 | 4 | 19454 | 50 |
NTRK2,MACF1,DTNA,ABLIM1 |
3.810e-02 | -3.27 | CEP128 (centrosomal protein 128) | protein interactions | 145508 | 289 | 3 | 19454 | 50 |
SORBS1,ABLIM1,NEBL |
3.815e-02 | -3.27 | RECEPTOR_TYR_KIN_II | prosite domains | PS00239 | 11 | 1 | 12186 | 43 |
NTRK2 |
3.815e-02 | -3.27 | GATA_ZN_FINGER_2 | prosite domains | PS50114 | 11 | 1 | 12186 | 43 |
TRPS1 |
3.855e-02 | -3.26 | solute:monoatomic cation symporter activity | molecular function | GO:0015294 | 117 | 2 | 18094 | 48 |
SLC1A2,SLC1A3 |
3.856e-02 | -3.26 | metencephalon development | biological process | GO:0022037 | 113 | 2 | 18204 | 50 |
PRKG1,RORA |
3.857e-02 | -3.26 | Glucagon signaling pathway | KEGG pathways | hsa04922 | 102 | 2 | 7161 | 22 |
ADCY2,ITPR2 |
3.857e-02 | -3.26 | Glucagon signaling pathway | KEGG pathways | ko04922 | 102 | 2 | 7161 | 22 |
ITPR2,ADCY2 |
3.871e-02 | -3.25 | Signalling by NGF | REACTOME pathways | R-HSA-166520 | 477 | 4 | 10285 | 28 |
NRG3,NTRK2,ADCY2,ITPR2 |
3.872e-02 | -3.25 | MED15 (mediator complex subunit 15) | protein interactions | 51586 | 121 | 2 | 19454 | 50 |
NFIA,QKI |
3.881e-02 | -3.25 | bone-humerus-Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour | COSMIC cancer mutations | bone-humerus-Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour | 107 | 2 | 16828 | 49 |
NEBL,PARD3B |
3.900e-02 | -3.24 | germ_cell_tumour | COSMIC cancer mutations | germ_cell_tumour | 867 | 6 | 16828 | 49 |
NTRK2,DCLK2,TRPS1,MACF1,PRKG1,BMPR1B |
3.908e-02 | -3.24 | tropomyosin binding | molecular function | GO:0005523 | 15 | 1 | 18094 | 48 |
NEBL |
3.908e-02 | -3.24 | phosphatidylglycerol binding | molecular function | GO:1901611 | 15 | 1 | 18094 | 48 |
PITPNC1 |
3.908e-02 | -3.24 | filamin binding | molecular function | GO:0031005 | 15 | 1 | 18094 | 48 |
NEBL |
3.918e-02 | -3.24 | regulation of circadian rhythm | biological process | GO:0042752 | 114 | 2 | 18204 | 50 |
RORA,PRKG1 |
3.920e-02 | -3.24 | Cadherin-like_sf | interpro domains | IPR015919 | 116 | 2 | 18521 | 50 |
PCDH9,CDH20 |
3.930e-02 | -3.24 | BRK1 (BRICK1 subunit of SCAR/WAVE actin nucleating complex) | protein interactions | 55845 | 122 | 2 | 19454 | 50 |
DTNA,NHSL1 |
3.943e-02 | -3.23 | human chr13q31.3 | chromosome location | human chr13q31.3 | 21 | 1 | 26134 | 50 |
GPC5 |
3.943e-02 | -3.23 | human chr10q23.1 | chromosome location | human chr10q23.1 | 21 | 1 | 26134 | 50 |
NRG3 |
3.947e-02 | -3.23 | pulmonary_blastoma | COSMIC cancer mutations | pulmonary_blastoma | 648 | 5 | 16828 | 49 |
BMPR1B,NTM,TRPS1,NEBL,ATP13A4 |
3.947e-02 | -3.23 | testis-germ_cell_tumour-seminoma | COSMIC cancer mutations | testis-germ_cell_tumour-seminoma | 648 | 5 | 16828 | 49 |
TRPS1,NTRK2,PRKG1,BMPR1B,DCLK2 |
3.947e-02 | -3.23 | pleura-pulmonary_blastoma | COSMIC cancer mutations | pleura-pulmonary_blastoma | 648 | 5 | 16828 | 49 |
NTM,BMPR1B,NEBL,ATP13A4,TRPS1 |
3.953e-02 | -3.23 | chondroitin sulfate biosynthesis | BIOCYC pathways | META_PWY-6569 | 18 | 1 | 902 | 2 |
CSGALNACT1 |
3.972e-02 | -3.23 | Cation_ATPase_C | pfam domains | PF00689 | 15 | 1 | 17795 | 48 |
ATP1A2 |
3.975e-02 | -3.23 | Znf_GATA | interpro domains | IPR000679 | 15 | 1 | 18521 | 50 |
TRPS1 |
3.975e-02 | -3.23 | ATPase_P-typ_cation-transptr_C | interpro domains | IPR006068 | 15 | 1 | 18521 | 50 |
ATP1A2 |
3.988e-02 | -3.22 | EF_HAND_2 | prosite domains | PS50222 | 215 | 3 | 12186 | 43 |
MACF1,RYR3,SPARCL1 |
3.988e-02 | -3.22 | PAX7 (paired box 7) | protein interactions | 5081 | 123 | 2 | 19454 | 50 |
NFIA,TRPS1 |
3.988e-02 | -3.22 | SPSB4 (splA/ryanodine receptor domain and SOCS box containing 4) | protein interactions | 92369 | 123 | 2 | 19454 | 50 |
PCDH9,LRIG1 |
4.008e-02 | -3.22 | learning or memory | biological process | GO:0007611 | 276 | 3 | 18204 | 50 |
NTRK2,ATP1A2,PTPRZ1 |
4.008e-02 | -3.22 | transcription cis-regulatory region binding | molecular function | GO:0000976 | 1485 | 8 | 18094 | 48 |
SOX5,NPAS3,GLIS3,RORA,RFX4,TRPS1,ZBTB20,NFIA |
4.009e-02 | -3.22 | ERBB2 Regulates Cell Motility | REACTOME pathways | R-HSA-6785631 | 15 | 1 | 10285 | 28 |
NRG3 |
4.009e-02 | -3.22 | N-Glycan antennae elongation | REACTOME pathways | R-HSA-975577 | 15 | 1 | 10285 | 28 |
MGAT4C |
4.009e-02 | -3.22 | Inhibition of adenylate cyclase pathway | REACTOME pathways | R-HSA-997269 | 15 | 1 | 10285 | 28 |
ADCY2 |
4.009e-02 | -3.22 | Adenylate cyclase inhibitory pathway | REACTOME pathways | R-HSA-170670 | 15 | 1 | 10285 | 28 |
ADCY2 |
4.022e-02 | -3.21 | ErbB receptor signaling network | Pathway Interaction DB | erbb_network_pathway | 13 | 1 | 2226 | 7 |
NRG3 |
4.023e-02 | -3.21 | Prot_kinase_dom | interpro domains | IPR000719 | 480 | 4 | 18521 | 50 |
BMPR1B,DCLK2,NTRK2,PRKG1 |
4.035e-02 | -3.21 | transcription regulatory region nucleic acid binding | molecular function | GO:0001067 | 1487 | 8 | 18094 | 48 |
GLIS3,TRPS1,NPAS3,SOX5,RFX4,ZBTB20,RORA,NFIA |
4.035e-02 | -3.21 | TWIST2 (twist family bHLH transcription factor 2) | protein interactions | 117581 | 16 | 1 | 19454 | 50 |
ZBTB20 |
4.035e-02 | -3.21 | CNTFR (ciliary neurotrophic factor receptor) | protein interactions | 1271 | 16 | 1 | 19454 | 50 |
LIFR |
4.035e-02 | -3.21 | AMMECR1L (AMMECR1 like) | protein interactions | 83607 | 16 | 1 | 19454 | 50 |
MACF1 |
4.035e-02 | -3.21 | SAPCD1 (suppressor APC domain containing 1) | protein interactions | 401251 | 16 | 1 | 19454 | 50 |
CTNNA2 |
4.035e-02 | -3.21 | Sumo3 (small ubiquitin-like modifier 3) | protein interactions | 20610 | 16 | 1 | 19454 | 50 |
ITPR2 |
4.035e-02 | -3.21 | FNDC8 (fibronectin type III domain containing 8) | protein interactions | 54752 | 16 | 1 | 19454 | 50 |
SPARCL1 |
4.035e-02 | -3.21 | GABRR1 (gamma-aminobutyric acid type A receptor subunit rho1) | protein interactions | 2569 | 16 | 1 | 19454 | 50 |
PRKG1 |
4.035e-02 | -3.21 | NBL1 (NBL1, DAN family BMP antagonist) | protein interactions | 4681 | 16 | 1 | 19454 | 50 |
LRIG1 |
4.035e-02 | -3.21 | ORM2 (orosomucoid 2) | protein interactions | 5005 | 16 | 1 | 19454 | 50 |
PPP2R2B |
4.035e-02 | -3.21 | CNTNAP2 (contactin associated protein 2) | protein interactions | 26047 | 16 | 1 | 19454 | 50 |
MACF1 |
4.035e-02 | -3.21 | CDH12 (cadherin 12) | protein interactions | 1010 | 16 | 1 | 19454 | 50 |
CTNNA2 |
4.043e-02 | -3.21 | peripheral nervous system neuron development | biological process | GO:0048935 | 15 | 1 | 18204 | 50 |
NTRK2 |
4.043e-02 | -3.21 | exit from mitosis | biological process | GO:0010458 | 15 | 1 | 18204 | 50 |
NFIA |
4.043e-02 | -3.21 | peripheral nervous system neuron differentiation | biological process | GO:0048934 | 15 | 1 | 18204 | 50 |
NTRK2 |
4.043e-02 | -3.21 | response to caffeine | biological process | GO:0031000 | 15 | 1 | 18204 | 50 |
RYR3 |
4.043e-02 | -3.21 | regulation of inositol phosphate biosynthetic process | biological process | GO:0010919 | 15 | 1 | 18204 | 50 |
PRKG1 |
4.043e-02 | -3.21 | intracellular potassium ion homeostasis | biological process | GO:0030007 | 15 | 1 | 18204 | 50 |
ATP1A2 |
4.043e-02 | -3.21 | cerebellar Purkinje cell layer formation | biological process | GO:0021694 | 15 | 1 | 18204 | 50 |
RORA |
4.043e-02 | -3.21 | sarcoplasmic reticulum calcium ion transport | biological process | GO:0070296 | 15 | 1 | 18204 | 50 |
RYR3 |
4.043e-02 | -3.21 | neuroblast division | biological process | GO:0055057 | 15 | 1 | 18204 | 50 |
SOX5 |
4.043e-02 | -3.21 | synapse maturation | biological process | GO:0060074 | 15 | 1 | 18204 | 50 |
NFIA |
4.043e-02 | -3.21 | negative regulation of amino acid transport | biological process | GO:0051956 | 15 | 1 | 18204 | 50 |
PRKG1 |
4.043e-02 | -3.21 | negative regulation of sodium ion transmembrane transport | biological process | GO:1902306 | 15 | 1 | 18204 | 50 |
ATP1A2 |
4.043e-02 | -3.21 | collateral sprouting | biological process | GO:0048668 | 15 | 1 | 18204 | 50 |
PRKG1 |
4.043e-02 | -3.21 | protein homotrimerization | biological process | GO:0070207 | 15 | 1 | 18204 | 50 |
SLC1A2 |
4.043e-02 | -3.21 | pyramidal neuron differentiation | biological process | GO:0021859 | 15 | 1 | 18204 | 50 |
DCLK2 |
4.043e-02 | -3.21 | regulation of neuron projection arborization | biological process | GO:0150011 | 15 | 1 | 18204 | 50 |
MACF1 |
4.043e-02 | -3.21 | positive regulation of glycogen biosynthetic process | biological process | GO:0045725 | 15 | 1 | 18204 | 50 |
SORBS1 |
4.083e-02 | -3.20 | Glycerol uptake facilitator protein | gene3d domains | 1.20.1080.10 | 14 | 1 | 14470 | 43 |
AQP4 |
4.092e-02 | -3.20 | phosphorus metabolic process | biological process | GO:0006793 | 1707 | 9 | 18204 | 50 |
PTPRZ1,ATP1A2,NTRK2,ADCY2,RORA,PRKG1,CSGALNACT1,DCLK2,BMPR1B |
4.101e-02 | -3.19 | Ig-like_dom_sf | interpro domains | IPR036179 | 483 | 4 | 18521 | 50 |
NTRK2,LSAMP,LRIG1,NTM |
4.106e-02 | -3.19 | oligoastrocytoma_Grade_III | COSMIC cancer mutations | oligoastrocytoma_Grade_III | 263 | 3 | 16828 | 49 |
SLC1A2,SOX5,RYR3 |
4.154e-02 | -3.18 | glycoprotein biosynthetic process | biological process | GO:0009101 | 280 | 3 | 18204 | 50 |
CSGALNACT1,MGAT4C,BMPR1B |
4.155e-02 | -3.18 | CNMP_BINDING_2 | prosite domains | PS00889 | 12 | 1 | 12186 | 43 |
PRKG1 |
4.156e-02 | -3.18 | LRRCT | smart domains | SM00082 | 83 | 2 | 9717 | 38 |
NTRK2,LRIG1 |
4.163e-02 | -3.18 | adenylate cyclase activity | molecular function | GO:0004016 | 16 | 1 | 18094 | 48 |
ADCY2 |
4.163e-02 | -3.18 | water channel activity | molecular function | GO:0015250 | 16 | 1 | 18094 | 48 |
AQP4 |
4.163e-02 | -3.18 | oxysterol binding | molecular function | GO:0008142 | 16 | 1 | 18094 | 48 |
RORA |
4.163e-02 | -3.18 | cGMP binding | molecular function | GO:0030553 | 16 | 1 | 18094 | 48 |
PRKG1 |
4.163e-02 | -3.18 | mitogen-activated protein kinase kinase kinase binding | molecular function | GO:0031435 | 16 | 1 | 18094 | 48 |
SASH1 |
4.166e-02 | -3.18 | SYP (synaptophysin) | protein interactions | 6855 | 126 | 2 | 19454 | 50 |
GPM6A,PITPNC1 |
4.170e-02 | -3.18 | synapse assembly | biological process | GO:0007416 | 118 | 2 | 18204 | 50 |
GPM6A,NRG3 |
4.196e-02 | -3.17 | breast-carcinoma-ER-PR-positive_carcinoma | COSMIC cancer mutations | breast-carcinoma-ER-PR-positive_carcinoma | 1881 | 10 | 16828 | 49 |
NPAS3,NRG3,MAML2,NTRK2,PPP2R2B,BMPR1B,MSI2,FBXL7,LIFR,LRIG1 |
4.196e-02 | -3.17 | ER-PR-positive_carcinoma | COSMIC cancer mutations | ER-PR-positive_carcinoma | 1881 | 10 | 16828 | 49 |
LIFR,FBXL7,LRIG1,MSI2,BMPR1B,MAML2,NRG3,PPP2R2B,NTRK2,NPAS3 |
4.208e-02 | -3.17 | mesothelioma | COSMIC cancer mutations | mesothelioma | 4477 | 19 | 16828 | 49 |
PTPRZ1,CTNND2,SOX5,RORA,PRKG1,BMPR1B,ITPR2,TRPS1,LRIG1,ATP13A4,DCLK2,MAML2,PPP2R2B,NTRK2,MSI2,QKI,PITPNC1,LIFR,FBXL7 |
4.235e-02 | -3.16 | cNMP-bd_CS | interpro domains | IPR018488 | 16 | 1 | 18521 | 50 |
PRKG1 |
4.267e-02 | -3.15 | neuron projection terminus | cellular component | GO:0044306 | 128 | 2 | 19108 | 49 |
NTRK2,SLC1A2 |
4.271e-02 | -3.15 | GRB2 events in ERBB2 signaling | REACTOME pathways | R-HSA-1963640 | 16 | 1 | 10285 | 28 |
NRG3 |
4.271e-02 | -3.15 | PI3K events in ERBB2 signaling | REACTOME pathways | R-HSA-1963642 | 16 | 1 | 10285 | 28 |
NRG3 |
4.271e-02 | -3.15 | PKA activation | REACTOME pathways | R-HSA-163615 | 16 | 1 | 10285 | 28 |
ADCY2 |
4.271e-02 | -3.15 | Rap1 signalling | REACTOME pathways | R-HSA-392517 | 16 | 1 | 10285 | 28 |
PRKG1 |
4.282e-02 | -3.15 | hypothalamus | COSMIC cancer mutations | hypothalamus | 15 | 1 | 16828 | 49 |
QKI |
4.282e-02 | -3.15 | Shcbp1 (Shc SH2-domain binding protein 1) | protein interactions | 20419 | 17 | 1 | 19454 | 50 |
GPC5 |
4.282e-02 | -3.15 | MSANTD2 (Myb/SANT DNA binding domain containing 2) | protein interactions | 79684 | 17 | 1 | 19454 | 50 |
SOX5 |
4.282e-02 | -3.15 | Sqstm1 (sequestosome 1) | protein interactions | 18412 | 17 | 1 | 19454 | 50 |
BMPR1B |
4.282e-02 | -3.15 | PAX4 (paired box 4) | protein interactions | 5078 | 17 | 1 | 19454 | 50 |
NTM |
4.282e-02 | -3.15 | Pef1 (penta-EF hand domain containing 1) | protein interactions | 67898 | 17 | 1 | 19454 | 50 |
QKI |
4.282e-02 | -3.15 | SEPSECS (Sep (O-phosphoserine) tRNA:Sec (selenocysteine) tRNA synthase) | protein interactions | 51091 | 17 | 1 | 19454 | 50 |
ABLIM1 |
4.282e-02 | -3.15 | TAGAP (T cell activation RhoGTPase activating protein) | protein interactions | 117289 | 17 | 1 | 19454 | 50 |
DTNA |
4.282e-02 | -3.15 | NOTCH4 (notch receptor 4) | protein interactions | 4855 | 17 | 1 | 19454 | 50 |
MAML2 |
4.282e-02 | -3.15 | RASL12 (RAS like family 12) | protein interactions | 51285 | 17 | 1 | 19454 | 50 |
BMPR1B |
4.282e-02 | -3.15 | DPP6 (dipeptidyl peptidase like 6) | protein interactions | 1804 | 17 | 1 | 19454 | 50 |
GPM6A |
4.286e-02 | -3.15 | MYB (MYB proto-oncogene, transcription factor) | protein interactions | 4602 | 128 | 2 | 19454 | 50 |
TRPS1,NFIA |
4.286e-02 | -3.15 | TEAD2 (TEA domain transcription factor 2) | protein interactions | 8463 | 128 | 2 | 19454 | 50 |
ZBTB20,TRPS1 |
4.286e-02 | -3.15 | ATF7IP (activating transcription factor 7 interacting protein) | protein interactions | 55729 | 128 | 2 | 19454 | 50 |
MACF1,SOX5 |
4.304e-02 | -3.15 | SH3DOMAIN | prints domains | PR00452 | 83 | 2 | 5227 | 21 |
NEBL,SORBS1 |
4.307e-02 | -3.14 | nonribosomal peptide biosynthetic process | biological process | GO:0019184 | 16 | 1 | 18204 | 50 |
SLC1A2 |
4.307e-02 | -3.14 | regulation of amino acid import across plasma membrane | biological process | GO:0010958 | 16 | 1 | 18204 | 50 |
ATP1A2 |
4.307e-02 | -3.14 | locomotory exploration behavior | biological process | GO:0035641 | 16 | 1 | 18204 | 50 |
ATP1A2 |
4.307e-02 | -3.14 | regulation of respiratory system process | biological process | GO:0044065 | 16 | 1 | 18204 | 50 |
ATP1A2 |
4.307e-02 | -3.14 | regulation of amino acid transmembrane transport | biological process | GO:1903789 | 16 | 1 | 18204 | 50 |
ATP1A2 |
4.307e-02 | -3.14 | non-proteinogenic amino acid biosynthetic process | biological process | GO:0170043 | 16 | 1 | 18204 | 50 |
SLC1A3 |
4.307e-02 | -3.14 | asymmetric cell division | biological process | GO:0008356 | 16 | 1 | 18204 | 50 |
SOX5 |
4.311e-02 | -3.14 | human chr5p15.31 | chromosome location | human chr5p15.31 | 23 | 1 | 26134 | 50 |
ADCY2 |
4.315e-02 | -3.14 | PROTEIN_KINASE_ATP | prosite domains | PS00107 | 377 | 4 | 12186 | 43 |
DCLK2,BMPR1B,NTRK2,PRKG1 |
4.321e-02 | -3.14 | CARM1 (coactivator associated arginine methyltransferase 1) | protein interactions | 10498 | 304 | 3 | 19454 | 50 |
DTNA,RORA,QKI |
4.329e-02 | -3.14 | ovary-carcinoma-mucinous_carcinoma | COSMIC cancer mutations | ovary-carcinoma-mucinous_carcinoma | 456 | 4 | 16828 | 49 |
DCLK2,PRKG1,BMPR1B,NTRK2 |
4.346e-02 | -3.14 | CHD7 (chromodomain helicase DNA binding protein 7) | protein interactions | 55636 | 129 | 2 | 19454 | 50 |
SOX5,ZBTB20 |
4.366e-02 | -3.13 | channel activity | molecular function | GO:0015267 | 502 | 4 | 18094 | 48 |
AQP4,ITPR2,RYR3,GPM6A |
4.368e-02 | -3.13 | pleura-mesothelioma | COSMIC cancer mutations | pleura-mesothelioma | 4189 | 18 | 16828 | 49 |
MSI2,QKI,FBXL7,PITPNC1,LIFR,DCLK2,MAML2,NTRK2,PPP2R2B,BMPR1B,PRKG1,ITPR2,TRPS1,LRIG1,PTPRZ1,CTNND2,SOX5,RORA |
4.385e-02 | -3.13 | SH3 | smart domains | SM00326 | 202 | 3 | 9717 | 38 |
SASH1,SORBS1,NEBL |
4.388e-02 | -3.13 | mucinous_carcinoma | COSMIC cancer mutations | mucinous_carcinoma | 458 | 4 | 16828 | 49 |
PRKG1,BMPR1B,DCLK2,NTRK2 |
4.388e-02 | -3.13 | Z disc | cellular component | GO:0030018 | 130 | 2 | 19108 | 49 |
NEBL,RYR3 |
4.392e-02 | -3.13 | passive transmembrane transporter activity | molecular function | GO:0022803 | 503 | 4 | 18094 | 48 |
GPM6A,RYR3,ITPR2,AQP4 |
4.407e-02 | -3.12 | PKP1 (plakophilin 1) | protein interactions | 5317 | 130 | 2 | 19454 | 50 |
CSGALNACT1,PPP2R2B |
4.417e-02 | -3.12 | transmembrane receptor protein phosphatase activity | molecular function | GO:0019198 | 17 | 1 | 18094 | 48 |
PTPRZ1 |
4.417e-02 | -3.12 | transmembrane receptor protein tyrosine phosphatase activity | molecular function | GO:0005001 | 17 | 1 | 18094 | 48 |
PTPRZ1 |
4.445e-02 | -3.11 | Glycosaminoglycan metabolism | REACTOME pathways | R-HSA-1630316 | 124 | 2 | 10285 | 28 |
GPC5,CSGALNACT1 |
4.468e-02 | -3.11 | NCOA2 (nuclear receptor coactivator 2) | protein interactions | 10499 | 131 | 2 | 19454 | 50 |
RORA,NFIA |
4.468e-02 | -3.11 | TRPS1 (transcriptional repressor GATA binding 1) | protein interactions | 7227 | 131 | 2 | 19454 | 50 |
NFIA,SOX5 |
4.468e-02 | -3.11 | ZNF609 (zinc finger protein 609) | protein interactions | 23060 | 131 | 2 | 19454 | 50 |
SOX5,NFIA |
4.490e-02 | -3.10 | ZZ | pfam domains | PF00569 | 17 | 1 | 17795 | 48 |
DTNA |
4.490e-02 | -3.10 | Carb_anhydrase | pfam domains | PF00194 | 17 | 1 | 17795 | 48 |
PTPRZ1 |
4.493e-02 | -3.10 | A/G_cyclase_CS | interpro domains | IPR018297 | 17 | 1 | 18521 | 50 |
ADCY2 |
4.493e-02 | -3.10 | CA_dom | interpro domains | IPR001148 | 17 | 1 | 18521 | 50 |
PTPRZ1 |
4.493e-02 | -3.10 | CA_dom_sf | interpro domains | IPR036398 | 17 | 1 | 18521 | 50 |
PTPRZ1 |
4.499e-02 | -3.10 | AFDN (afadin, adherens junction formation factor) | protein interactions | 4301 | 309 | 3 | 19454 | 50 |
MACF1,DTNA,SORBS1 |
4.506e-02 | -3.10 | Cadherins | gene3d domains | 2.60.40.60 | 114 | 2 | 14470 | 43 |
PCDH9,CDH20 |
4.507e-02 | -3.10 | ductal_carcinoma | COSMIC cancer mutations | ductal_carcinoma | 15798 | 49 | 16828 | 49 |
RYR3,NEBL,PTPRZ1,CTNND2,SLC1A2,PARD3B,GLIS3,SPARCL1,PITPNC1,NKAIN3,NTRK2,BMPR1B,ITPR2,TRPS1,LSAMP,SLC1A3,NPAS3,PCDH9,MSI2,NFIA,LIFR,FBXL7,DTNA,NHSL1,ABLIM1,NRG3,PRKG1,MACF1,ATP13A4,SORBS1,GPC5,CDH20,QKI,MAML2,AQP4,CSGALNACT1,ATP1A2,LRIG1,SASH1,NTM,ZBTB20,SOX5,RORA,MGAT4C,DCLK2,ADCY2,RFX4,PPP2R2B,GPM6A |
4.519e-02 | -3.10 | protein phosphatase type 2A complex | cellular component | GO:0000159 | 18 | 1 | 19108 | 49 |
PPP2R2B |
4.529e-02 | -3.09 | SERTAD4 (SERTA domain containing 4) | protein interactions | 56256 | 18 | 1 | 19454 | 50 |
PPP2R2B |
4.529e-02 | -3.09 | Cnot2 (CCR4-NOT transcription complex, subunit 2) | protein interactions | 72068 | 18 | 1 | 19454 | 50 |
MACF1 |
4.529e-02 | -3.09 | KLHL1 (kelch like family member 1) | protein interactions | 57626 | 18 | 1 | 19454 | 50 |
BMPR1B |
4.529e-02 | -3.09 | SELL (selectin L) | protein interactions | 6402 | 18 | 1 | 19454 | 50 |
PRKG1 |
4.529e-02 | -3.09 | TTC29 (tetratricopeptide repeat domain 29) | protein interactions | 83894 | 18 | 1 | 19454 | 50 |
MACF1 |
4.529e-02 | -3.09 | Tgfbr1 (transforming growth factor, beta receptor I) | protein interactions | 21812 | 18 | 1 | 19454 | 50 |
BMPR1B |
4.529e-02 | -3.09 | NKIRAS1 (NFKB inhibitor interacting Ras like 1) | protein interactions | 28512 | 18 | 1 | 19454 | 50 |
BMPR1B |
4.529e-02 | -3.09 | OPCML (opioid binding protein/cell adhesion molecule like) | protein interactions | 4978 | 18 | 1 | 19454 | 50 |
NTM |
4.529e-02 | -3.09 | ACAP1 (ArfGAP with coiled-coil, ankyrin repeat and PH domains 1) | protein interactions | 9744 | 18 | 1 | 19454 | 50 |
NEBL |
4.530e-02 | -3.09 | IVL (involucrin) | protein interactions | 3713 | 132 | 2 | 19454 | 50 |
PPP2R2B,CSGALNACT1 |
4.532e-02 | -3.09 | PKA activation in glucagon signalling | REACTOME pathways | R-HSA-164378 | 17 | 1 | 10285 | 28 |
ADCY2 |
4.532e-02 | -3.09 | Elevation of cytosolic Ca2+ levels | REACTOME pathways | R-HSA-139853 | 17 | 1 | 10285 | 28 |
ITPR2 |
4.532e-02 | -3.09 | PKA-mediated phosphorylation of CREB | REACTOME pathways | R-HSA-111931 | 17 | 1 | 10285 | 28 |
ADCY2 |
4.535e-02 | -3.09 | C11orf52 (chromosome 11 open reading frame 52) | protein interactions | 91894 | 310 | 3 | 19454 | 50 |
ABLIM1,DTNA,MACF1 |
4.557e-02 | -3.09 | cytoskeletal protein binding | molecular function | GO:0008092 | 989 | 6 | 18094 | 48 |
DCLK2,CTNNA2,SORBS1,NEBL,ABLIM1,MACF1 |
4.560e-02 | -3.09 | action potential | biological process | GO:0001508 | 124 | 2 | 18204 | 50 |
NTRK2,ATP1A2 |
4.560e-02 | -3.09 | positive regulation of lipid metabolic process | biological process | GO:0045834 | 124 | 2 | 18204 | 50 |
ZBTB20,SORBS1 |
4.560e-02 | -3.09 | cardiocyte differentiation | biological process | GO:0035051 | 124 | 2 | 18204 | 50 |
NEBL,PRKG1 |
4.565e-02 | -3.09 | ovary-carcinoma-endometrioid_carcinoma | COSMIC cancer mutations | ovary-carcinoma-endometrioid_carcinoma | 464 | 4 | 16828 | 49 |
DCLK2,BMPR1B,PRKG1,NTRK2 |
4.567e-02 | -3.09 | inorganic ion transmembrane transport | biological process | GO:0098660 | 715 | 5 | 18204 | 50 |
GPM6A,SLC1A3,RYR3,ITPR2,ATP1A2 |
4.569e-02 | -3.09 | Cholinergic synapse | KEGG pathways | hsa04725 | 112 | 2 | 7161 | 22 |
ITPR2,ADCY2 |
4.570e-02 | -3.09 | cGMP metabolic process | biological process | GO:0046068 | 17 | 1 | 18204 | 50 |
RORA |
4.570e-02 | -3.09 | protein trimerization | biological process | GO:0070206 | 17 | 1 | 18204 | 50 |
SLC1A2 |
4.570e-02 | -3.09 | viral genome replication | biological process | GO:0019079 | 17 | 1 | 18204 | 50 |
NFIA |
4.570e-02 | -3.09 | membrane depolarization during cardiac muscle cell action potential | biological process | GO:0086012 | 17 | 1 | 18204 | 50 |
ATP1A2 |
4.570e-02 | -3.09 | cell communication by electrical coupling involved in cardiac conduction | biological process | GO:0086064 | 17 | 1 | 18204 | 50 |
ATP1A2 |
4.570e-02 | -3.09 | ureter development | biological process | GO:0072189 | 17 | 1 | 18204 | 50 |
NFIA |
4.570e-02 | -3.09 | cellular response to ATP | biological process | GO:0071318 | 17 | 1 | 18204 | 50 |
RYR3 |
4.570e-02 | -3.09 | positive regulation of glycogen metabolic process | biological process | GO:0070875 | 17 | 1 | 18204 | 50 |
SORBS1 |
4.570e-02 | -3.09 | T-helper 17 type immune response | biological process | GO:0072538 | 17 | 1 | 18204 | 50 |
RORA |
4.570e-02 | -3.09 | heparin metabolic process | biological process | GO:0030202 | 17 | 1 | 18204 | 50 |
CSGALNACT1 |
4.570e-02 | -3.09 | retinal rod cell differentiation | biological process | GO:0060221 | 17 | 1 | 18204 | 50 |
NTRK2 |
4.570e-02 | -3.09 | cell migration in hindbrain | biological process | GO:0021535 | 17 | 1 | 18204 | 50 |
CTNNA2 |
4.596e-02 | -3.08 | DWA | smart domains | SM00523 | 12 | 1 | 9717 | 38 |
NFIA |
4.596e-02 | -3.08 | ZnF_GATA | smart domains | SM00401 | 12 | 1 | 9717 | 38 |
TRPS1 |
4.626e-02 | -3.07 | actomyosin structure organization | biological process | GO:0031032 | 125 | 2 | 18204 | 50 |
SORBS1,NEBL |
4.629e-02 | -3.07 | LPA4-mediated signaling events | Pathway Interaction DB | lpa4_pathway | 15 | 1 | 2226 | 7 |
ADCY2 |
4.631e-02 | -3.07 | cellular response to growth factor stimulus | biological process | GO:0071363 | 494 | 4 | 18204 | 50 |
NFIA,BMPR1B,SOX5,NTRK2 |
4.631e-02 | -3.07 | modulation of chemical synaptic transmission | biological process | GO:0050804 | 494 | 4 | 18204 | 50 |
ATP1A2,NRG3,NTRK2,SLC1A3 |
4.653e-02 | -3.07 | NUFIP1 (nuclear FMR1 interacting protein 1) | protein interactions | 26747 | 134 | 2 | 19454 | 50 |
GPM6A,NTM |
4.660e-02 | -3.07 | regulation of trans-synaptic signaling | biological process | GO:0099177 | 495 | 4 | 18204 | 50 |
SLC1A3,NTRK2,ATP1A2,NRG3 |
4.671e-02 | -3.06 | phosphatidylcholine transporter activity | molecular function | GO:0008525 | 18 | 1 | 18094 | 48 |
PITPNC1 |
4.671e-02 | -3.06 | transmembrane receptor protein tyrosine kinase activator activity | molecular function | GO:0030297 | 18 | 1 | 18094 | 48 |
NRG3 |
4.693e-02 | -3.06 | limbic system development | biological process | GO:0021761 | 126 | 2 | 18204 | 50 |
ATP1A2,DCLK2 |
4.716e-02 | -3.05 | SOX15 (SRY-box transcription factor 15) | protein interactions | 6665 | 135 | 2 | 19454 | 50 |
TRPS1,NFIA |
4.722e-02 | -3.05 | central_nervous_system-brain-glioma-astrocytoma_Grade_IV | COSMIC cancer mutations | central_nervous_system-brain-glioma-astrocytoma_Grade_IV | 15813 | 49 | 16828 | 49 |
GPC5,QKI,CDH20,AQP4,MAML2,PRKG1,MACF1,ATP13A4,SORBS1,MGAT4C,ADCY2,DCLK2,RFX4,PPP2R2B,GPM6A,ATP1A2,CSGALNACT1,LRIG1,SASH1,NTM,SOX5,ZBTB20,RORA,SLC1A2,PARD3B,SPARCL1,GLIS3,PITPNC1,NKAIN3,NTRK2,NEBL,RYR3,PTPRZ1,CTNND2,MSI2,FBXL7,NFIA,LIFR,DTNA,NHSL1,NRG3,ABLIM1,BMPR1B,ITPR2,TRPS1,SLC1A3,LSAMP,PCDH9,NPAS3 |
4.746e-02 | -3.05 | regulation of anatomical structure size | biological process | GO:0090066 | 498 | 4 | 18204 | 50 |
AQP4,MACF1,ATP1A2,PRKG1 |
4.748e-02 | -3.05 | LRR_4 | pfam domains | PF12799 | 18 | 1 | 17795 | 48 |
LRIG1 |
4.748e-02 | -3.05 | Guanylate_cyc | pfam domains | PF00211 | 18 | 1 | 17795 | 48 |
ADCY2 |
4.752e-02 | -3.05 | A/G_cyclase | interpro domains | IPR001054 | 18 | 1 | 18521 | 50 |
ADCY2 |
4.752e-02 | -3.05 | Nucleotide_cyclase | interpro domains | IPR029787 | 18 | 1 | 18521 | 50 |
ADCY2 |
4.752e-02 | -3.05 | Leu-rich_rpt_Cys-con_subtyp | interpro domains | IPR006553 | 18 | 1 | 18521 | 50 |
FBXL7 |
4.752e-02 | -3.05 | Leu-rich_rpt_4 | interpro domains | IPR025875 | 18 | 1 | 18521 | 50 |
LRIG1 |
4.760e-02 | -3.05 | response to amino acid | biological process | GO:0043200 | 127 | 2 | 18204 | 50 |
NTRK2,SLC1A2 |
4.764e-02 | -3.04 | parallel fiber to Purkinje cell synapse | cellular component | GO:0098688 | 19 | 1 | 19108 | 49 |
GPM6A |
4.764e-02 | -3.04 | cation-transporting ATPase complex | cellular component | GO:0090533 | 19 | 1 | 19108 | 49 |
ATP1A2 |
4.768e-02 | -3.04 | haematopoietic_and_lymphoid_tissue-central_nervous_system-lymphoid_neoplasm-primary_central_nervous_system_lymphoma | COSMIC cancer mutations | haematopoietic_and_lymphoid_tissue-central_nervous_system-lymphoid_neoplasm-primary_central_nervous_system_lymphoma | 683 | 5 | 16828 | 49 |
SASH1,PARD3B,ZBTB20,NRG3,MACF1 |
4.768e-02 | -3.04 | primary_central_nervous_system_lymphoma | COSMIC cancer mutations | primary_central_nervous_system_lymphoma | 683 | 5 | 16828 | 49 |
PARD3B,SASH1,NRG3,ZBTB20,MACF1 |
4.774e-02 | -3.04 | INKA1 (inka box actin regulator 1) | protein interactions | 389119 | 19 | 1 | 19454 | 50 |
ZBTB20 |
4.774e-02 | -3.04 | OSM (oncostatin M) | protein interactions | 5008 | 19 | 1 | 19454 | 50 |
LIFR |
4.774e-02 | -3.04 | PLA2G4E (phospholipase A2 group IVE) | protein interactions | 123745 | 19 | 1 | 19454 | 50 |
PPP2R2B |
4.774e-02 | -3.04 | C3orf62 (chromosome 3 open reading frame 62) | protein interactions | 375341 | 19 | 1 | 19454 | 50 |
ATP1A2 |
4.774e-02 | -3.04 | CNTNAP4 (contactin associated protein family member 4) | protein interactions | 85445 | 19 | 1 | 19454 | 50 |
MACF1 |
4.774e-02 | -3.04 | GCHFR (GTP cyclohydrolase I feedback regulator) | protein interactions | 2644 | 19 | 1 | 19454 | 50 |
NEBL |
4.774e-02 | -3.04 | PHYHIPL (phytanoyl-CoA 2-hydroxylase interacting protein like) | protein interactions | 84457 | 19 | 1 | 19454 | 50 |
GPM6A |
4.774e-02 | -3.04 | RIT2 (Ras like without CAAX 2) | protein interactions | 6014 | 19 | 1 | 19454 | 50 |
DTNA |
4.774e-02 | -3.04 | TNR (tenascin R) | protein interactions | 7143 | 19 | 1 | 19454 | 50 |
PTPRZ1 |
4.774e-02 | -3.04 | SPZ1 (spermatogenic leucine zipper 1) | protein interactions | 84654 | 19 | 1 | 19454 | 50 |
DTNA |
4.782e-02 | -3.04 | regulation of multicellular organismal development | biological process | GO:2000026 | 1484 | 8 | 18204 | 50 |
MACF1,QKI,SASH1,BMPR1B,SOX5,NTRK2,TRPS1,PTPRZ1 |
4.792e-02 | -3.04 | cGMP effects | REACTOME pathways | R-HSA-418457 | 18 | 1 | 10285 | 28 |
PRKG1 |
4.802e-02 | -3.04 | PK_Tyr_Ser-Thr | pfam domains | PF07714 | 130 | 2 | 17795 | 48 |
BMPR1B,NTRK2 |
4.804e-02 | -3.04 | carboxylic acid transport | biological process | GO:0046942 | 297 | 3 | 18204 | 50 |
NTRK2,SLC1A2,SLC1A3 |
4.809e-02 | -3.03 | N-glycan biosynthesis, complex type | KEGG pathways | M00075 | 16 | 1 | 7161 | 22 |
MGAT4C |
4.809e-02 | -3.03 | N-glycan biosynthesis, complex type | KEGG pathways | hsa_M00075 | 16 | 1 | 7161 | 22 |
MGAT4C |
4.809e-02 | -3.03 | cAMP signaling | KEGG pathways | hsa_M00695 | 16 | 1 | 7161 | 22 |
ADCY2 |
4.809e-02 | -3.03 | cAMP signaling | KEGG pathways | M00695 | 16 | 1 | 7161 | 22 |
ADCY2 |
4.827e-02 | -3.03 | myelination | biological process | GO:0042552 | 128 | 2 | 18204 | 50 |
QKI,NTRK2 |
4.832e-02 | -3.03 | cardiac myofibril assembly | biological process | GO:0055003 | 18 | 1 | 18204 | 50 |
NEBL |
4.832e-02 | -3.03 | negative regulation of anoikis | biological process | GO:2000811 | 18 | 1 | 18204 | 50 |
NTRK2 |
4.832e-02 | -3.03 | dendritic spine morphogenesis | biological process | GO:0060997 | 18 | 1 | 18204 | 50 |
CTNND2 |
4.832e-02 | -3.03 | negative regulation of platelet activation | biological process | GO:0010544 | 18 | 1 | 18204 | 50 |
PRKG1 |
4.832e-02 | -3.03 | negative regulation of sodium ion transport | biological process | GO:0010766 | 18 | 1 | 18204 | 50 |
ATP1A2 |
4.839e-02 | -3.03 | central_nervous_system-optic_nerve-glioma-astrocytoma_Grade_I | COSMIC cancer mutations | central_nervous_system-optic_nerve-glioma-astrocytoma_Grade_I | 17 | 1 | 16828 | 49 |
QKI |
4.839e-02 | -3.03 | optic_nerve | COSMIC cancer mutations | optic_nerve | 17 | 1 | 16828 | 49 |
QKI |
4.842e-02 | -3.03 | TBL1X (transducin beta like 1 X-linked) | protein interactions | 6907 | 137 | 2 | 19454 | 50 |
NFIA,SOX5 |
4.843e-02 | -3.03 | oligoastrocytoma_Grade_II | COSMIC cancer mutations | oligoastrocytoma_Grade_II | 121 | 2 | 16828 | 49 |
CDH20,DTNA |
4.843e-02 | -3.03 | organic acid transport | biological process | GO:0015849 | 298 | 3 | 18204 | 50 |
NTRK2,SLC1A3,SLC1A2 |
4.859e-02 | -3.02 | human chr18q12.1 | chromosome location | human chr18q12.1 | 26 | 1 | 26134 | 50 |
DTNA |
4.865e-02 | -3.02 | MFAP5-mediated ovarian cancer cell motility and invasiveness | WikiPathways | WP3301 | 12 | 1 | 5310 | 22 |
RYR3 |
4.865e-02 | -3.02 | Bone Morphogenic Protein (BMP) Signalling and Regulation | WikiPathways | WP1425 | 12 | 1 | 5310 | 22 |
BMPR1B |
4.881e-02 | -3.02 | Ion Channels and Their Functional Role in Vascular Endothelium | SMPDB pathways | SMP0063778 | 17 | 1 | 1369 | 4 |
PRKG1 |
4.894e-02 | -3.02 | response to organophosphorus | biological process | GO:0046683 | 129 | 2 | 18204 | 50 |
ITPR2,RYR3 |
4.911e-02 | -3.01 | sequence-specific double-stranded DNA binding | molecular function | GO:1990837 | 1547 | 8 | 18094 | 48 |
RORA,RFX4,SOX5,NPAS3,GLIS3,NFIA,ZBTB20,TRPS1 |
4.924e-02 | -3.01 | water transmembrane transporter activity | molecular function | GO:0005372 | 19 | 1 | 18094 | 48 |
AQP4 |
4.924e-02 | -3.01 | alkali metal ion binding | molecular function | GO:0031420 | 19 | 1 | 18094 | 48 |
ATP1A2 |
4.924e-02 | -3.01 | transmembrane receptor protein serine/threonine kinase activity | molecular function | GO:0004675 | 19 | 1 | 18094 | 48 |
BMPR1B |
4.936e-02 | -3.01 | Alpha carbonic anhydrase | gene3d domains | 3.10.200.10 | 17 | 1 | 14470 | 43 |
PTPRZ1 |
4.940e-02 | -3.01 | ACTA1 (actin alpha 1, skeletal muscle) | protein interactions | 58 | 321 | 3 | 19454 | 50 |
MACF1,DTNA,SORBS1 |
4.951e-02 | -3.01 | monoatomic cation homeostasis | biological process | GO:0055080 | 505 | 4 | 18204 | 50 |
ATP1A2,SLC1A3,RYR3,ATP13A4 |
4.962e-02 | -3.00 | ensheathment of neurons | biological process | GO:0007272 | 130 | 2 | 18204 | 50 |
NTRK2,QKI |
4.962e-02 | -3.00 | axon ensheathment | biological process | GO:0008366 | 130 | 2 | 18204 | 50 |
QKI,NTRK2 |
4.968e-02 | -3.00 | DUSP22 (dual specificity phosphatase 22) | protein interactions | 56940 | 139 | 2 | 19454 | 50 |
CTNNA2,QKI |
4.968e-02 | -3.00 | SPCS2 (signal peptidase complex subunit 2) | protein interactions | 9789 | 139 | 2 | 19454 | 50 |
MGAT4C,GPC5 |
4.971e-02 | -3.00 | carbohydrate derivative metabolic process | biological process | GO:1901135 | 975 | 6 | 18204 | 50 |
RORA,ADCY2,BMPR1B,CSGALNACT1,MGAT4C,ATP1A2 |
4.987e-02 | -3.00 | ligand-gated monoatomic cation channel activity | molecular function | GO:0099094 | 135 | 2 | 18094 | 48 |
RYR3,ITPR2 |