Gene Ontology Enrichment Results

Homer de novo Motif Enrichment Results
Known Motif Enrichment Results

Text file version of complete results (i.e. open with Excel)

biological process: Functional groupings of proteins (Gene Ontology)

molecular function: Mechanistic actions of proteins (Gene Ontology)

cellular component: Protein localization (Gene Ontology)

chromosome location: Genes with similar chromosome localization (NCBI Gene)

KEGG pathways: Groups of proteins in the same pathways (KEGG)

protein interactions: "Proteins interacting with a common protein (BIND, EcoCyc, HPRD)" (NCBI Gene)

interpro domains: Proteins with similar domains and features (Interpro)

pfam domains: Proteins with similar domains and features (Pfam)

smart domains: Proteins with similar domains and features (SMART)

gene3d domains: Proteins with similar domains and features (Gene3D)

prosite domains: Proteins with similar domains and features (Prosite)

prints domains: Proteins with similar domains and features (PRINTS)

MSigDB lists: "Genes sets for pathways, factor/miRNA target predictions, expression patterns, etc." (MSigDB)

BIOCYC pathways: Groups of proteins in the same pathways (BIOCYC)

COSMIC cancer mutations: Genes mutated in similar cancers (COSMIC)

GWAS genes: Genes mutated in similar diseases (GWAS Catalog)

Lipid Maps pathways: Groups of proteins in the same lipid pathways (Lipid Maps/Biosystems)

Pathway Interaction DB: Groups of proteins in the same pathways (Pathway Interaction Database)

REACTOME pathways: Groups of proteins in the same pathways (REACTOME)

SMPDB pathways: Groups of proteins in the same pathways (SMPDB)

WikiPathways: Groups of proteins in the same pathways (Wikipathways)

Enriched Categories

P-value	ln(P)	Term	GO Tree	GO ID	# of Genes in Term	# of Target Genes in Term	# of Total Genes	# of Target Genes	Common Genes
2.370e-11	-24.47	prostate-carcinoma	COSMIC cancer mutations	prostate-carcinoma	9000	48	16828	50	SASH1,GPC5,CTNND2,NPAS3,ATP13A4,PPP2R2B,LSAMP,PRKCA,DCLK2,BMPR1B,NRG3,NEBL,TRPS1,MSI2,QKI,CSGALNACT1,RFX4,CDH20,NHSL1,MACF1,NTM,ABLIM1,NFIA,NKAIN3,SPARCL1,TRPM3,MAML2,DTNA,NTRK2,PTPRZ1,SLC1A2,RORA,PITPNC1,LIFR,GPM6A,FBXL7,RYR3,PARD3B,SOX5,SLC1A3,FMN2,ADCY2,SLC4A4,SORBS1,ZBTB20,GLIS3,ITPR2,PARD3
1.470e-10	-22.64	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-Burkitt_lymphoma	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-Burkitt_lymphoma	2119	25	16828	50	SLC1A2,NTRK2,BMPR1B,MAML2,PPP2R2B,LSAMP,ATP13A4,NKAIN3,GPC5,CTNND2,NPAS3,NHSL1,SASH1,RFX4,PARD3,CSGALNACT1,ITPR2,SLC1A3,ADCY2,FMN2,RYR3,SOX5,FBXL7,GPM6A,NRG3
1.470e-10	-22.64	Burkitt_lymphoma	COSMIC cancer mutations	Burkitt_lymphoma	2119	25	16828	50	RFX4,SLC1A2,NTRK2,PARD3,BMPR1B,CSGALNACT1,ITPR2,MAML2,PPP2R2B,SLC1A3,ADCY2,FMN2,LSAMP,RYR3,SOX5,ATP13A4,FBXL7,NKAIN3,GPM6A,GPC5,CTNND2,NPAS3,NHSL1,SASH1,NRG3
3.083e-10	-21.90	central_nervous_system-brain-primitive_neuroectodermal_tumour-medulloblastoma	COSMIC cancer mutations	central_nervous_system-brain-primitive_neuroectodermal_tumour-medulloblastoma	7205	43	16828	50	NKAIN3,NFIA,TRPM3,NHSL1,MACF1,NTM,ABLIM1,NTRK2,PTPRZ1,SLC1A2,MAML2,GPM6A,FBXL7,PARD3B,SOX5,RYR3,RORA,PITPNC1,LIFR,PARD3,FMN2,ADCY2,SLC1A3,SORBS1,SLC4A4,ITPR2,GLIS3,ZBTB20,ATP13A4,SASH1,NPAS3,CTNND2,GPC5,LSAMP,PPP2R2B,PRKCA,DCLK2,NRG3,NEBL,TRPS1,CSGALNACT1,QKI,RFX4
5.074e-10	-21.40	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-acute_lymphoblastic_B_cell_leukaemia	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-acute_lymphoblastic_B_cell_leukaemia	3828	32	16828	50	MGAT4C,FBXL7,GPM6A,SOX5,RYR3,NEBL,NRG3,RORA,LIFR,PARD3,CSGALNACT1,FMN2,ADCY2,SLC1A3,ZBTB20,GLIS3,ITPR2,SLC4A4,NKAIN3,NFIA,ATP13A4,SASH1,NTM,CTNND2,GPC5,BMPR1B,SLC1A2,PTPRZ1,NTRK2,LSAMP,PPP2R2B,MAML2
5.074e-10	-21.40	acute_lymphoblastic_B_cell_leukaemia	COSMIC cancer mutations	acute_lymphoblastic_B_cell_leukaemia	3828	32	16828	50	CSGALNACT1,PARD3,SLC4A4,ZBTB20,GLIS3,ITPR2,ADCY2,SLC1A3,FMN2,RYR3,SOX5,GPM6A,MGAT4C,FBXL7,LIFR,RORA,NRG3,NEBL,NTRK2,SLC1A2,PTPRZ1,BMPR1B,MAML2,PPP2R2B,LSAMP,ATP13A4,NFIA,NKAIN3,CTNND2,GPC5,NTM,SASH1
2.525e-09	-19.80	mantle_cell_lymphoma	COSMIC cancer mutations	mantle_cell_lymphoma	2849	27	16828	50	PPP2R2B,LSAMP,MAML2,PRKCA,SLC1A2,NTRK2,SASH1,GPC5,CTNND2,TRPM3,NKAIN3,ATP13A4,ADCY2,SLC1A3,FMN2,ITPR2,PARD3,RFX4,NEBL,NRG3,TRPS1,LIFR,FBXL7,GPM6A,RYR3,PARD3B,SOX5
4.444e-09	-19.23	diffuse_large_B_cell_lymphoma	COSMIC cancer mutations	diffuse_large_B_cell_lymphoma	4151	32	16828	50	ITPR2,FMN2,ADCY2,SLC1A3,CDH20,PARD3,CSGALNACT1,QKI,TRPS1,LIFR,NEBL,NRG3,RORA,SOX5,RYR3,FBXL7,GPM6A,DTNA,PRKCA,MAML2,LSAMP,PPP2R2B,SLC1A2,NTRK2,GPC5,CTNND2,MACF1,SASH1,ATP13A4,AQP4,SPARCL1,NKAIN3
6.508e-09	-18.85	central_nervous_system-brainstem-glioma-astrocytoma_Grade_IV	COSMIC cancer mutations	central_nervous_system-brainstem-glioma-astrocytoma_Grade_IV	2531	25	16828	50	SASH1,GPC5,CTNND2,NKAIN3,ATP13A4,LSAMP,PPP2R2B,PRKCA,MAML2,PTPRZ1,NRG3,RORA,LIFR,FBXL7,GPM6A,SOX5,RYR3,FMN2,SLC1A3,ADCY2,ITPR2,ZBTB20,PARD3,QKI,CDH20
9.808e-09	-18.44	PRNP (prion protein (Kanno blood group))	protein interactions	5621	1118	16	19454	50	SPARCL1,GPM6A,TRPS1,PTPRZ1,MSI2,SORBS1,SLC4A4,MACF1,ABLIM1,SLC1A3,AQP4,LSAMP,NHSL1,QKI,TRPM3,MAML2
1.702e-08	-17.89	brainstem	COSMIC cancer mutations	brainstem	3102	27	16828	50	ZBTB20,ITPR2,ADCY2,SLC1A3,FMN2,CDH20,QKI,PARD3,LIFR,NRG3,RORA,SOX5,RYR3,GPM6A,FBXL7,PRKCA,MAML2,LSAMP,PPP2R2B,SLC1A2,PTPRZ1,NPAS3,GPC5,CTNND2,SASH1,ATP13A4,NKAIN3
2.647e-08	-17.45	haematopoietic_and_lymphoid_tissue-haematopoietic_neoplasm-acute_myeloid_leukaemia_therapy_related	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue-haematopoietic_neoplasm-acute_myeloid_leukaemia_therapy_related	1523	19	16828	50	NRG3,RORA,NEBL,GPC5,CTNND2,NKAIN3,FBXL7,SOX5,RYR3,FMN2,SLC1A3,ADCY2,LSAMP,PPP2R2B,MAML2,ITPR2,QKI,PARD3,NTRK2
2.647e-08	-17.45	acute_myeloid_leukaemia_therapy_related	COSMIC cancer mutations	acute_myeloid_leukaemia_therapy_related	1523	19	16828	50	PPP2R2B,SLC1A3,ADCY2,LSAMP,FMN2,MAML2,ITPR2,QKI,PARD3,NTRK2,RORA,NRG3,NEBL,GPC5,CTNND2,NKAIN3,FBXL7,RYR3,SOX5
2.701e-08	-17.43	lymph_node	COSMIC cancer mutations	lymph_node	1703	20	16828	50	LIFR,CTNND2,TRPS1,GPC5,NRG3,NEBL,PARD3B,ATP13A4,SOX5,RYR3,GPM6A,TRPM3,PRKCA,MAML2,ITPR2,DTNA,SLC1A3,LSAMP,NTRK2,PARD3
3.117e-08	-17.28	cerebellum	COSMIC cancer mutations	cerebellum	769	14	16828	50	RYR3,PTPRZ1,PARD3B,NTRK2,PARD3,QKI,GPC5,CTNND2,ITPR2,NPAS3,ABLIM1,MAML2,NEBL,NRG3
3.293e-08	-17.23	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-mantle_cell_lymphoma	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-mantle_cell_lymphoma	2737	25	16828	50	ITPR2,SLC1A3,FMN2,ADCY2,RFX4,PARD3,TRPS1,LIFR,NEBL,NRG3,SOX5,PARD3B,RYR3,FBXL7,GPM6A,PRKCA,MAML2,LSAMP,PPP2R2B,SLC1A2,NTRK2,GPC5,CTNND2,SASH1,NKAIN3
6.862e-08	-16.49	angiosarcoma	COSMIC cancer mutations	angiosarcoma	2192	22	16828	50	ADCY2,FMN2,SLC1A3,ITPR2,PARD3,CDH20,NEBL,NRG3,FBXL7,GPM6A,SOX5,RYR3,LSAMP,PPP2R2B,MAML2,SLC1A2,PTPRZ1,NTRK2,SASH1,GPC5,CTNND2,NKAIN3
6.862e-08	-16.49	soft_tissue-blood_vessel-angiosarcoma	COSMIC cancer mutations	soft_tissue-blood_vessel-angiosarcoma	2192	22	16828	50	PTPRZ1,SLC1A2,CDH20,NTRK2,PARD3,ITPR2,MAML2,PPP2R2B,FMN2,ADCY2,LSAMP,SLC1A3,RYR3,SOX5,FBXL7,GPM6A,NKAIN3,CTNND2,GPC5,NEBL,SASH1,NRG3
8.025e-08	-16.34	blood_vessel	COSMIC cancer mutations	blood_vessel	2211	22	16828	50	NEBL,SASH1,NRG3,GPC5,CTNND2,FBXL7,GPM6A,NKAIN3,RYR3,SOX5,PPP2R2B,FMN2,SLC1A3,ADCY2,LSAMP,ITPR2,MAML2,PARD3,SLC1A2,PTPRZ1,CDH20,NTRK2
9.851e-08	-16.13	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-diffuse_large_B_cell_lymphoma	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-diffuse_large_B_cell_lymphoma	3608	28	16828	50	SLC1A2,PPP2R2B,LSAMP,MAML2,PRKCA,NKAIN3,SPARCL1,AQP4,ATP13A4,SASH1,MACF1,CTNND2,GPC5,QKI,CSGALNACT1,PARD3,CDH20,ADCY2,FMN2,ITPR2,GPM6A,FBXL7,RYR3,SOX5,RORA,NRG3,NEBL,LIFR
1.156e-07	-15.97	lymphoid_neoplasm	COSMIC cancer mutations	lymphoid_neoplasm	12233	50	16828	50	LIFR,PITPNC1,RORA,SOX5,PARD3B,RYR3,FBXL7,MGAT4C,GPM6A,GLIS3,ZBTB20,ITPR2,SORBS1,SLC4A4,FMN2,SLC1A3,ADCY2,PARD3,NTM,ABLIM1,MACF1,NHSL1,AQP4,TRPM3,SPARCL1,NKAIN3,NFIA,DTNA,MAML2,PTPRZ1,SLC1A2,NTRK2,TRPS1,NEBL,NRG3,MSI2,CDH20,RFX4,CSGALNACT1,QKI,NPAS3,CTNND2,GPC5,SASH1,ATP13A4,DCLK2,PRKCA,LSAMP,PPP2R2B,BMPR1B
1.345e-07	-15.82	upper_aerodigestive_tract-mouth-carcinoma-squamous_cell_carcinoma	COSMIC cancer mutations	upper_aerodigestive_tract-mouth-carcinoma-squamous_cell_carcinoma	6953	39	16828	50	SLC1A2,PTPRZ1,PPP2R2B,LSAMP,DTNA,DCLK2,MAML2,PRKCA,TRPM3,ATP13A4,NHSL1,SASH1,CTNND2,GPC5,NTM,ABLIM1,MACF1,PARD3,QKI,CSGALNACT1,RFX4,CDH20,ADCY2,FMN2,ITPR2,ZBTB20,SORBS1,SLC4A4,MGAT4C,FBXL7,GPM6A,RYR3,SOX5,PARD3B,PITPNC1,NEBL,RORA,NRG3,TRPS1
3.305e-07	-14.92	central_nervous_system-cerebellum-primitive_neuroectodermal_tumour-medulloblastoma-SHH_subtype	COSMIC cancer mutations	central_nervous_system-cerebellum-primitive_neuroectodermal_tumour-medulloblastoma-SHH_subtype	653	12	16828	50	RYR3,PTPRZ1,PARD3B,NTRK2,PARD3,CTNND2,NPAS3,ITPR2,ABLIM1,MAML2,NEBL,NRG3
3.359e-07	-14.91	SHH_subtype	COSMIC cancer mutations	SHH_subtype	654	12	16828	50	PARD3,NTRK2,PTPRZ1,MAML2,ITPR2,RYR3,PARD3B,NRG3,NEBL,CTNND2,NPAS3,ABLIM1
3.606e-07	-14.84	chondroblastoma	COSMIC cancer mutations	chondroblastoma	534	11	16828	50	SOX5,RYR3,NKAIN3,GPM6A,GPC5,CTNND2,NRG3,LSAMP,ADCY2,FMN2,PPP2R2B
9.106e-07	-13.91	myelodysplastic_syndrome	COSMIC cancer mutations	myelodysplastic_syndrome	1174	15	16828	50	NRG3,NPAS3,FBXL7,NFIA,NKAIN3,RYR3,SOX5,LSAMP,ADCY2,DCLK2,PRKCA,PARD3,BMPR1B,SLC1A2,NTRK2
9.106e-07	-13.91	haematopoietic_and_lymphoid_tissue-haematopoietic_neoplasm-myelodysplastic_syndrome	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue-haematopoietic_neoplasm-myelodysplastic_syndrome	1174	15	16828	50	SLC1A2,NTRK2,PARD3,BMPR1B,DCLK2,PRKCA,LSAMP,ADCY2,RYR3,SOX5,FBXL7,NFIA,NKAIN3,NPAS3,NRG3
1.111e-06	-13.71	haematopoietic_and_lymphoid_tissue-lymph_node-lymphoid_neoplasm-mantle_cell_lymphoma	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue-lymph_node-lymphoid_neoplasm-mantle_cell_lymphoma	476	10	16828	50	TRPM3,GPM6A,RYR3,ATP13A4,LSAMP,NRG3,CTNND2,GPC5,MAML2,PRKCA
1.158e-06	-13.67	mouth	COSMIC cancer mutations	mouth	9004	43	16828	50	RYR3,PARD3B,SOX5,FBXL7,MGAT4C,GPM6A,LIFR,PITPNC1,RORA,PARD3,ITPR2,ZBTB20,SLC4A4,SORBS1,ADCY2,SLC1A3,FMN2,TRPM3,NTM,ABLIM1,MACF1,NHSL1,PTPRZ1,SLC1A2,NTRK2,DTNA,MAML2,TRPS1,NEBL,NRG3,RFX4,CDH20,QKI,CSGALNACT1,ATP13A4,GPC5,CTNND2,NPAS3,SASH1,DCLK2,PRKCA,PPP2R2B,LSAMP
1.520e-06	-13.40	soft_tissue	COSMIC cancer mutations	soft_tissue	5828	34	16828	50	CDH20,PARD3,SORBS1,ITPR2,GLIS3,SLC1A3,ADCY2,FMN2,SOX5,PARD3B,RYR3,GPM6A,FBXL7,TRPS1,NRG3,RORA,NEBL,NTRK2,PTPRZ1,SLC1A2,MAML2,LSAMP,PPP2R2B,AQP4,NKAIN3,NFIA,TRPM3,SPARCL1,MACF1,NPAS3,GPC5,CTNND2,SASH1,NHSL1
1.623e-06	-13.33	CTNNA1 (catenin alpha 1)	protein interactions	1495	325	8	19454	50	SASH1,MACF1,PARD3,ABLIM1,NHSL1,DTNA,NEBL,SORBS1
1.738e-06	-13.26	haematopoietic_and_lymphoid_tissue-haematopoietic_neoplasm	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue-haematopoietic_neoplasm	764	12	16828	50	LSAMP,ADCY2,MAML2,PARD3,SLC1A2,NTRK2,NRG3,GPC5,FBXL7,NKAIN3,SOX5,RYR3
3.827e-06	-12.47	oesophagus-carcinoma	COSMIC cancer mutations	oesophagus-carcinoma	4269	28	16828	50	NFIA,TRPM3,ATP13A4,NHSL1,MACF1,NTM,CTNND2,NTRK2,PTPRZ1,PPP2R2B,GPM6A,FBXL7,PARD3B,SOX5,RYR3,NRG3,LIFR,TRPS1,CSGALNACT1,PARD3,CDH20,RFX4,ADCY2,FMN2,SLC4A4,SORBS1,ITPR2,ZBTB20
4.503e-06	-12.31	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-chronic_lymphocytic_leukaemia-small_lymphocytic_lymphoma	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-chronic_lymphocytic_leukaemia-small_lymphocytic_lymphoma	3511	25	16828	50	PTPRZ1,NTRK2,BMPR1B,DTNA,PRKCA,PPP2R2B,LSAMP,TRPM3,CTNND2,GPC5,NPAS3,MACF1,PARD3,SLC4A4,SLC1A3,FMN2,ADCY2,MSI2,RYR3,PARD3B,MGAT4C,FBXL7,LIFR,PITPNC1,NRG3
4.503e-06	-12.31	chronic_lymphocytic_leukaemia-small_lymphocytic_lymphoma	COSMIC cancer mutations	chronic_lymphocytic_leukaemia-small_lymphocytic_lymphoma	3511	25	16828	50	NRG3,PITPNC1,MACF1,LIFR,GPC5,CTNND2,NPAS3,MGAT4C,FBXL7,TRPM3,RYR3,PARD3B,PPP2R2B,LSAMP,MSI2,SLC1A3,FMN2,ADCY2,SLC4A4,PRKCA,DTNA,BMPR1B,PARD3,NTRK2,PTPRZ1
6.349e-06	-11.97	oesophagus-carcinoma-squamous_cell_carcinoma	COSMIC cancer mutations	oesophagus-carcinoma-squamous_cell_carcinoma	6486	35	16828	50	AQP4,ATP13A4,SPARCL1,TRPM3,MACF1,CTNND2,GPC5,ABLIM1,NPAS3,SASH1,PTPRZ1,BMPR1B,MAML2,PRKCA,DCLK2,RYR3,PARD3B,SOX5,GPM6A,MGAT4C,FBXL7,LIFR,TRPS1,NRG3,NEBL,PITPNC1,CSGALNACT1,PARD3,SORBS1,SLC4A4,GLIS3,ZBTB20,ITPR2,ADCY2,FMN2
7.125e-06	-11.85	Par3_HAL_N_term	pfam domains	PF12053	2	2	17795	48	PARD3B,PARD3
7.143e-06	-11.85	Par3/HAL_N	interpro domains	IPR021922	2	2	18521	50	PARD3B,PARD3
8.104e-06	-11.72	intestinal_adenocarcinoma	COSMIC cancer mutations	intestinal_adenocarcinoma	7225	37	16828	50	PARD3B,SOX5,RYR3,FBXL7,LIFR,TRPS1,NRG3,RORA,PITPNC1,NEBL,CDH20,RFX4,CSGALNACT1,QKI,PARD3,SLC4A4,ITPR2,ZBTB20,ADCY2,FMN2,AQP4,ATP13A4,NFIA,TRPM3,MACF1,NTM,NPAS3,CTNND2,SASH1,NHSL1,NTRK2,SLC1A2,PTPRZ1,PRKCA,MAML2,DCLK2,LSAMP
8.104e-06	-11.72	stomach-carcinoma-intestinal_adenocarcinoma	COSMIC cancer mutations	stomach-carcinoma-intestinal_adenocarcinoma	7225	37	16828	50	NTRK2,PTPRZ1,SLC1A2,LSAMP,MAML2,PRKCA,DCLK2,NFIA,TRPM3,AQP4,ATP13A4,SASH1,NHSL1,MACF1,CTNND2,NPAS3,NTM,QKI,CSGALNACT1,PARD3,RFX4,CDH20,FMN2,ADCY2,SLC4A4,ZBTB20,ITPR2,FBXL7,RYR3,PARD3B,SOX5,RORA,NRG3,NEBL,PITPNC1,LIFR,TRPS1
1.004e-05	-11.51	nervous system development	biological process	GO:0007399	2185	18	18204	50	RORA,NTRK2,SLC1A2,BMPR1B,MSI2,NRG3,PTPRZ1,CTNND2,LSAMP,GPM6A,RFX4,SOX5,PARD3,NTM,DCLK2,SLC1A3,QKI,NFIA
1.082e-05	-11.43	pharynx	COSMIC cancer mutations	pharynx	2696	21	16828	50	NHSL1,PITPNC1,NRG3,CTNND2,GPC5,NPAS3,MACF1,NFIA,RYR3,PARD3B,ATP13A4,FMN2,DTNA,SORBS1,SLC4A4,PRKCA,QKI,PTPRZ1,SLC1A2,RFX4,NTRK2
1.109e-05	-11.41	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm	7307	37	16828	50	NTRK2,PTPRZ1,SLC1A2,BMPR1B,PRKCA,MAML2,LSAMP,PPP2R2B,ATP13A4,NKAIN3,SPARCL1,MACF1,ABLIM1,CTNND2,GPC5,SASH1,NHSL1,CDH20,RFX4,CSGALNACT1,QKI,PARD3,GLIS3,ITPR2,FMN2,SLC1A3,ADCY2,SOX5,PARD3B,RYR3,GPM6A,MGAT4C,FBXL7,LIFR,NRG3,RORA,NEBL
1.119e-05	-11.40	skin-face-carcinoma-squamous_cell_carcinoma	COSMIC cancer mutations	skin-face-carcinoma-squamous_cell_carcinoma	2036	18	16828	50	ITPR2,PPP2R2B,LSAMP,MSI2,FMN2,PTPRZ1,PARD3,CSGALNACT1,TRPS1,GPC5,ABLIM1,MACF1,NEBL,RORA,NRG3,AQP4,TRPM3,GPM6A
1.227e-05	-11.31	lung-right_lower_lobe-carcinoma-adenocarcinoma	COSMIC cancer mutations	lung-right_lower_lobe-carcinoma-adenocarcinoma	5692	32	16828	50	PPP2R2B,LSAMP,MAML2,DTNA,NTRK2,PTPRZ1,MACF1,CTNND2,GPC5,NTM,NPAS3,NKAIN3,TRPM3,ATP13A4,ADCY2,SLC1A3,FMN2,SORBS1,SLC4A4,ITPR2,PARD3,CDH20,NRG3,NEBL,LIFR,TRPS1,GPM6A,FBXL7,MGAT4C,RYR3,PARD3B,SOX5
1.227e-05	-11.31	right_lower_lobe	COSMIC cancer mutations	right_lower_lobe	5692	32	16828	50	ATP13A4,TRPM3,NKAIN3,GPC5,CTNND2,NTM,NPAS3,MACF1,PTPRZ1,NTRK2,DTNA,MAML2,PPP2R2B,LSAMP,RYR3,PARD3B,SOX5,MGAT4C,FBXL7,GPM6A,TRPS1,LIFR,NEBL,NRG3,CDH20,PARD3,ITPR2,SORBS1,SLC4A4,ADCY2,SLC1A3,FMN2
1.251e-05	-11.29	cell junction organization	biological process	GO:0034330	532	9	18204	50	CDH20,PARD3,NFIA,SORBS1,GPM6A,PRKCA,CTNND2,NRG3,SPARCL1
1.551e-05	-11.07	carcinoid-endocrine_tumour	COSMIC cancer mutations	carcinoid-endocrine_tumour	7752	38	16828	50	MACF1,CTNND2,GPC5,ABLIM1,SASH1,NHSL1,ATP13A4,NKAIN3,TRPM3,MAML2,PRKCA,DCLK2,PPP2R2B,LSAMP,NTRK2,PTPRZ1,SLC1A2,BMPR1B,LIFR,TRPS1,RORA,NRG3,NEBL,RYR3,SOX5,GPM6A,FBXL7,SLC4A4,GLIS3,ITPR2,FMN2,ADCY2,SLC1A3,RFX4,CDH20,QKI,CSGALNACT1,PARD3
2.100e-05	-10.77	trunk	COSMIC cancer mutations	trunk	3554	24	16828	50	SASH1,NRG3,NEBL,MACF1,LIFR,TRPS1,CTNND2,ABLIM1,NPAS3,SPARCL1,MGAT4C,RYR3,ATP13A4,SOX5,PPP2R2B,SLC1A3,LSAMP,MAML2,DCLK2,GLIS3,PARD3,NTRK2,PTPRZ1,CDH20
2.220e-05	-10.72	face	COSMIC cancer mutations	face	2139	18	16828	50	CSGALNACT1,PARD3,PTPRZ1,PPP2R2B,FMN2,LSAMP,MSI2,ITPR2,GPM6A,TRPM3,AQP4,RORA,NRG3,NEBL,MACF1,TRPS1,GPC5,ABLIM1
2.226e-05	-10.71	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-follicular_lymphoma	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-follicular_lymphoma	981	12	16828	50	SOX5,PARD3,NKAIN3,CTNND2,GPC5,ITPR2,PRKCA,ADCY2,LSAMP,SASH1,RORA,NRG3
2.256e-05	-10.70	MAPT (microtubule associated protein tau)	protein interactions	4137	948	11	19454	50	SORBS1,PPP2R2B,NEBL,CTNND2,SLC1A3,NTM,SLC1A2,LSAMP,ABLIM1,GPM6A,PRKCA
2.506e-05	-10.59	Glutamatergic synapse	KEGG pathways	ko04724	114	5	7161	23	SLC1A3,SLC1A2,PRKCA,ADCY2,ITPR2
2.506e-05	-10.59	Glutamatergic synapse	KEGG pathways	hsa04724	114	5	7161	23	SLC1A2,SLC1A3,ITPR2,ADCY2,PRKCA
2.823e-05	-10.48	bone-humerus-other-chondroblastoma	COSMIC cancer mutations	bone-humerus-other-chondroblastoma	301	7	16828	50	GPM6A,NKAIN3,SOX5,ADCY2,FMN2,PPP2R2B,GPC5
2.852e-05	-10.47	humerus	COSMIC cancer mutations	humerus	546	9	16828	50	NEBL,FMN2,ADCY2,PPP2R2B,GPC5,GPM6A,NKAIN3,SOX5,PARD3B
3.259e-05	-10.33	cervix-carcinoma-squamous_cell_carcinoma	COSMIC cancer mutations	cervix-carcinoma-squamous_cell_carcinoma	11789	47	16828	50	RFX4,CDH20,QKI,CSGALNACT1,TRPS1,NRG3,NEBL,BMPR1B,PRKCA,DCLK2,PPP2R2B,LSAMP,ATP13A4,GPC5,CTNND2,NPAS3,SASH1,PARD3,SLC4A4,SORBS1,GLIS3,ITPR2,ZBTB20,SLC1A3,FMN2,ADCY2,RYR3,PARD3B,SOX5,GPM6A,FBXL7,MGAT4C,LIFR,RORA,PITPNC1,NTRK2,PTPRZ1,SLC1A2,MAML2,DTNA,NFIA,SPARCL1,TRPM3,MACF1,ABLIM1,NTM,NHSL1
3.304e-05	-10.32	cervix	COSMIC cancer mutations	cervix	11793	47	16828	50	PRKCA,DCLK2,LSAMP,PPP2R2B,BMPR1B,NPAS3,GPC5,CTNND2,SASH1,ATP13A4,CDH20,RFX4,CSGALNACT1,QKI,TRPS1,NRG3,NEBL,MAML2,DTNA,NTRK2,SLC1A2,PTPRZ1,MACF1,NTM,ABLIM1,NHSL1,NFIA,TRPM3,SPARCL1,SLC4A4,SORBS1,ZBTB20,ITPR2,GLIS3,FMN2,SLC1A3,ADCY2,PARD3,LIFR,RORA,PITPNC1,SOX5,PARD3B,RYR3,GPM6A,FBXL7,MGAT4C
3.520e-05	-10.25	plasma membrane	cellular component	GO:0005886	5538	28	19108	49	DTNA,PARD3B,FMN2,LSAMP,GPC5,BMPR1B,SORBS1,NRG3,NTM,GPM6A,LIFR,SLC1A3,PRKCA,NKAIN3,CDH20,ADCY2,MACF1,TRPM3,SLC1A2,PARD3,RYR3,NTRK2,CTNND2,SLC4A4,ITPR2,AQP4,PTPRZ1,ATP13A4
3.574e-05	-10.24	lung-right_upper_lobe-carcinoma-adenocarcinoma	COSMIC cancer mutations	lung-right_upper_lobe-carcinoma-adenocarcinoma	10376	44	16828	50	DCLK2,PRKCA,PPP2R2B,LSAMP,BMPR1B,GPC5,CTNND2,NPAS3,SASH1,ATP13A4,RFX4,CDH20,CSGALNACT1,TRPS1,NEBL,NRG3,DTNA,SLC1A2,PTPRZ1,NTRK2,NTM,ABLIM1,MACF1,TRPM3,NFIA,NKAIN3,GLIS3,ZBTB20,ITPR2,SORBS1,SLC4A4,ADCY2,SLC1A3,FMN2,PARD3,LIFR,PITPNC1,RORA,RYR3,SOX5,PARD3B,MGAT4C,FBXL7,GPM6A
3.574e-05	-10.24	right_upper_lobe	COSMIC cancer mutations	right_upper_lobe	10376	44	16828	50	LSAMP,PPP2R2B,PRKCA,DCLK2,DTNA,BMPR1B,NTRK2,PTPRZ1,SLC1A2,SASH1,MACF1,NTM,ABLIM1,NPAS3,GPC5,CTNND2,NKAIN3,NFIA,TRPM3,ATP13A4,FMN2,SLC1A3,ADCY2,SORBS1,SLC4A4,ZBTB20,GLIS3,ITPR2,CSGALNACT1,PARD3,CDH20,RFX4,NRG3,RORA,NEBL,PITPNC1,LIFR,TRPS1,GPM6A,FBXL7,MGAT4C,PARD3B,SOX5,RYR3
3.683e-05	-10.21	follicular_lymphoma	COSMIC cancer mutations	follicular_lymphoma	1209	13	16828	50	PARD3,ITPR2,PRKCA,LSAMP,ADCY2,SOX5,AQP4,NKAIN3,GPC5,CTNND2,RORA,SASH1,NRG3
4.274e-05	-10.06	Neurotransmitter uptake and Metabolism In Glial Cells	REACTOME pathways	R-HSA-112313	4	2	10285	28	SLC1A3,SLC1A2
4.274e-05	-10.06	Astrocytic Glutamate-Glutamine Uptake And Metabolism	REACTOME pathways	R-HSA-210455	4	2	10285	28	SLC1A2,SLC1A3
4.540e-05	-10.00	neurogenesis	biological process	GO:0022008	1334	13	18204	50	PARD3,NTM,DCLK2,NFIA,QKI,SLC1A3,SOX5,GPM6A,BMPR1B,RORA,NTRK2,PTPRZ1,CTNND2
4.623e-05	-9.98	SFN (stratifin)	protein interactions	2810	671	9	19454	50	FMN2,ABLIM1,MACF1,NFIA,PARD3B,PARD3,SASH1,SORBS1,PPP2R2B
5.229e-05	-9.86	anatomical structure morphogenesis	biological process	GO:0009653	2225	17	18204	50	QKI,SLC1A3,NFIA,CDH20,PARD3,SOX5,GPM6A,ABLIM1,CTNND2,PTPRZ1,NRG3,PRKCA,RORA,CSGALNACT1,NTRK2,BMPR1B,NEBL
5.266e-05	-9.85	generation of neurons	biological process	GO:0048699	1158	12	18204	50	BMPR1B,NTRK2,RORA,SOX5,PTPRZ1,CTNND2,PARD3,NTM,DCLK2,NFIA,SLC1A3,GPM6A
5.769e-05	-9.76	cell periphery	cellular component	GO:0071944	6020	29	19108	49	ATP13A4,PTPRZ1,SPARCL1,AQP4,ITPR2,CTNND2,SLC4A4,NTRK2,PARD3,RYR3,ADCY2,CDH20,NKAIN3,SLC1A2,TRPM3,MACF1,SLC1A3,PRKCA,GPM6A,LIFR,NTM,BMPR1B,SORBS1,NRG3,LSAMP,FMN2,GPC5,PARD3B,DTNA
5.801e-05	-9.75	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-plasma_cell_myeloma	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-plasma_cell_myeloma	1263	13	16828	50	NEBL,ADCY2,FMN2,NRG3,NTM,ABLIM1,TRPS1,CTNND2,MACF1,GPM6A,ATP13A4,RYR3,NTRK2
5.801e-05	-9.75	plasma_cell_myeloma	COSMIC cancer mutations	plasma_cell_myeloma	1263	13	16828	50	GPM6A,ATP13A4,RYR3,NRG3,NEBL,MACF1,NTM,ABLIM1,CTNND2,TRPS1,NTRK2,ADCY2,FMN2
6.140e-05	-9.70	upper_aerodigestive_tract-mouth-carcinoma	COSMIC cancer mutations	upper_aerodigestive_tract-mouth-carcinoma	6426	33	16828	50	SLC1A2,MAML2,PPP2R2B,TRPM3,NPAS3,ABLIM1,NTM,CTNND2,GPC5,MACF1,NHSL1,SASH1,CDH20,RFX4,PARD3,QKI,ZBTB20,SLC4A4,SORBS1,SLC1A3,ADCY2,FMN2,PARD3B,SOX5,RYR3,MGAT4C,FBXL7,GPM6A,TRPS1,LIFR,PITPNC1,NRG3,RORA
6.227e-05	-9.68	system development	biological process	GO:0048731	3533	22	18204	50	DCLK2,NFIA,PARD3,NTM,TRPS1,LSAMP,PTPRZ1,CTNND2,NTRK2,RORA,SLC1A2,NEBL,SLC1A3,QKI,RFX4,SOX5,GPM6A,NRG3,CSGALNACT1,BMPR1B,PRKCA,MSI2
6.544e-05	-9.63	prostate	COSMIC cancer mutations	prostate	13883	50	16828	50	SLC1A3,FMN2,ADCY2,ITPR2,GLIS3,ZBTB20,SLC4A4,SORBS1,PARD3,PITPNC1,RORA,LIFR,MGAT4C,FBXL7,GPM6A,RYR3,SOX5,PARD3B,DTNA,MAML2,PTPRZ1,SLC1A2,NTRK2,NHSL1,NTM,ABLIM1,MACF1,SPARCL1,TRPM3,NFIA,NKAIN3,AQP4,MSI2,QKI,CSGALNACT1,RFX4,CDH20,NEBL,NRG3,TRPS1,PPP2R2B,LSAMP,DCLK2,PRKCA,BMPR1B,SASH1,GPC5,CTNND2,NPAS3,ATP13A4
6.856e-05	-9.59	glutamate:sodium symporter activity	molecular function	GO:0015501	5	2	18094	48	SLC1A2,SLC1A3
6.856e-05	-9.59	high-affinity L-glutamate transmembrane transporter activity	molecular function	GO:0005314	5	2	18094	48	SLC1A2,SLC1A3
7.355e-05	-9.52	D-aspartate import across plasma membrane	biological process	GO:0070779	5	2	18204	50	SLC1A3,SLC1A2
7.355e-05	-9.52	D-aspartate transmembrane transport	biological process	GO:0070777	5	2	18204	50	SLC1A3,SLC1A2
8.255e-05	-9.40	NTM (neurotrimin)	protein interactions	50863	33	3	19454	50	NTM,LSAMP,GPM6A
9.109e-05	-9.30	nodular	COSMIC cancer mutations	nodular	1515	14	16828	50	SPARCL1,ATP13A4,NEBL,ABLIM1,NPAS3,CTNND2,MACF1,CDH20,PTPRZ1,NTRK2,FMN2,GLIS3,DCLK2,SLC4A4
1.006e-04	-9.20	upper_aerodigestive_tract-larynx-carcinoma-squamous_cell_carcinoma	COSMIC cancer mutations	upper_aerodigestive_tract-larynx-carcinoma-squamous_cell_carcinoma	1946	16	16828	50	CSGALNACT1,BMPR1B,FMN2,ZBTB20,ITPR2,MAML2,SLC4A4,MGAT4C,GPM6A,RYR3,SOX5,PARD3B,NEBL,RORA,NPAS3,MACF1
1.018e-04	-9.19	larynx	COSMIC cancer mutations	larynx	1948	16	16828	50	MAML2,SLC4A4,ZBTB20,ITPR2,FMN2,BMPR1B,CSGALNACT1,MACF1,NPAS3,RORA,NEBL,RYR3,PARD3B,SOX5,GPM6A,MGAT4C
1.022e-04	-9.19	DAG and IP3 signaling	REACTOME pathways	R-HSA-1489509	34	3	10285	28	ITPR2,ADCY2,PRKCA
1.035e-04	-9.18	adenoma	COSMIC cancer mutations	adenoma	2873	20	16828	50	NEBL,SASH1,NPAS3,GPC5,CTNND2,LIFR,MACF1,TRPM3,GPM6A,SOX5,RYR3,ADCY2,ZBTB20,DCLK2,PRKCA,PARD3,BMPR1B,CDH20,PTPRZ1,NTRK2
1.061e-04	-9.15	RYDR_ITPR	pfam domains	PF01365	6	2	17795	48	ITPR2,RYR3
1.061e-04	-9.15	Ins145_P3_rec	pfam domains	PF08709	6	2	17795	48	ITPR2,RYR3
1.061e-04	-9.15	RIH_assoc	pfam domains	PF08454	6	2	17795	48	ITPR2,RYR3
1.064e-04	-9.15	RIH_assoc-dom	interpro domains	IPR013662	6	2	18521	50	ITPR2,RYR3
1.064e-04	-9.15	Ryanodine_IP3_receptor	interpro domains	IPR015925	6	2	18521	50	ITPR2,RYR3
1.064e-04	-9.15	Ins145_P3_rcpt	interpro domains	IPR014821	6	2	18521	50	RYR3,ITPR2
1.064e-04	-9.15	RyR/IP3R_RIH_dom_sf	interpro domains	IPR035910	6	2	18521	50	RYR3,ITPR2
1.064e-04	-9.15	RIH_dom	interpro domains	IPR000699	6	2	18521	50	RYR3,ITPR2
1.101e-04	-9.11	D-amino acid transport	biological process	GO:0042940	6	2	18204	50	SLC1A2,SLC1A3
1.101e-04	-9.11	L-aspartate import across plasma membrane	biological process	GO:0140009	6	2	18204	50	SLC1A3,SLC1A2
1.153e-04	-9.07	multicellular organism development	biological process	GO:0007275	3957	23	18204	50	SLC1A3,QKI,SOX5,RFX4,GPM6A,MSI2,PRKCA,BMPR1B,CSGALNACT1,NRG3,CDH20,NTM,PARD3,NFIA,DCLK2,TRPS1,LSAMP,NEBL,RORA,SLC1A2,NTRK2,CTNND2,PTPRZ1
1.173e-04	-9.05	adherens junction	cellular component	GO:0005912	188	5	19108	49	CTNND2,CDH20,SORBS1,PARD3,PARD3B
1.215e-04	-9.02	PLC-gamma1 signalling	REACTOME pathways	R-HSA-167021	36	3	10285	28	ITPR2,ADCY2,PRKCA
1.215e-04	-9.02	EGFR interacts with phospholipase C-gamma	REACTOME pathways	R-HSA-212718	36	3	10285	28	ADCY2,PRKCA,ITPR2
1.245e-04	-8.99	cell junction assembly	biological process	GO:0034329	285	6	18204	50	SORBS1,GPM6A,CDH20,PARD3,NRG3,PRKCA
1.257e-04	-8.98	lung-carcinoma-small_cell_carcinoma	COSMIC cancer mutations	lung-carcinoma-small_cell_carcinoma	9908	42	16828	50	PPP2R2B,MAML2,PRKCA,DTNA,DCLK2,BMPR1B,NTRK2,PTPRZ1,SASH1,MACF1,CTNND2,GPC5,ABLIM1,NPAS3,NTM,NFIA,NKAIN3,SPARCL1,TRPM3,ATP13A4,MSI2,FMN2,SLC4A4,SORBS1,ITPR2,QKI,CSGALNACT1,PARD3,RFX4,CDH20,RORA,NRG3,PITPNC1,NEBL,LIFR,TRPS1,GPM6A,FBXL7,MGAT4C,RYR3,SOX5,PARD3B
1.277e-04	-8.97	small_cell_carcinoma	COSMIC cancer mutations	small_cell_carcinoma	9913	42	16828	50	SPARCL1,TRPM3,NFIA,NKAIN3,ATP13A4,SASH1,GPC5,CTNND2,NPAS3,NTM,ABLIM1,MACF1,BMPR1B,PTPRZ1,NTRK2,PPP2R2B,DCLK2,DTNA,MAML2,PRKCA,MGAT4C,FBXL7,GPM6A,RYR3,PARD3B,SOX5,PITPNC1,NEBL,RORA,NRG3,TRPS1,LIFR,PARD3,QKI,CSGALNACT1,RFX4,CDH20,MSI2,FMN2,ITPR2,SLC4A4,SORBS1
1.284e-04	-8.96	IP3 receptor type 1 binding core, RIH domain	gene3d domains	1.25.10.30	6	2	14470	43	ITPR2,RYR3
1.349e-04	-8.91	neuron differentiation	biological process	GO:0030182	1081	11	18204	50	SLC1A3,NFIA,DCLK2,NTM,PARD3,GPM6A,CTNND2,PTPRZ1,NTRK2,RORA,BMPR1B
1.483e-04	-8.82	SDF	pfam domains	PF00375	7	2	17795	48	SLC1A3,SLC1A2
1.487e-04	-8.81	Na-dicarboxylate_symporter_CS	interpro domains	IPR018107	7	2	18521	50	SLC1A2,SLC1A3
1.487e-04	-8.81	Na:dicarbo_symporter_sf	interpro domains	IPR036458	7	2	18521	50	SLC1A3,SLC1A2
1.487e-04	-8.81	Na-dicarboxylate_symporter	interpro domains	IPR001991	7	2	18521	50	SLC1A3,SLC1A2
1.490e-04	-8.81	FLOT1 (flotillin 1)	protein interactions	10211	453	7	19454	50	SOX5,SORBS1,PARD3,DTNA,ABLIM1,FMN2,MACF1
1.534e-04	-8.78	metal ion transmembrane transporter activity	molecular function	GO:0046873	442	7	18094	48	TRPM3,RYR3,GPM6A,SLC1A2,SLC4A4,ITPR2,SLC1A3
1.611e-04	-8.73	autonomic_ganglia	COSMIC cancer mutations	autonomic_ganglia	4005	24	16828	50	GLIS3,SLC4A4,ADCY2,FMN2,RFX4,PARD3,TRPS1,NEBL,PITPNC1,RYR3,PARD3B,FBXL7,GPM6A,MAML2,SLC1A2,PTPRZ1,NTRK2,CTNND2,NPAS3,MACF1,NHSL1,SASH1,AQP4,NFIA
1.662e-04	-8.70	cellular response to alkaloid	biological process	GO:0071312	39	3	18204	50	SLC1A2,SLC1A3,RYR3
1.721e-04	-8.67	Salivary secretion	KEGG pathways	ko04970	90	4	7161	23	ITPR2,PRKCA,ADCY2,RYR3
1.721e-04	-8.67	Salivary secretion	KEGG pathways	hsa04970	90	4	7161	23	RYR3,ITPR2,PRKCA,ADCY2
1.794e-04	-8.63	Sodium:dicarboxylate symporter	gene3d domains	1.10.3860.10	7	2	14470	43	SLC1A3,SLC1A2
2.028e-04	-8.50	bone-tibia-other-chondroblastoma	COSMIC cancer mutations	bone-tibia-other-chondroblastoma	98	4	16828	50	CTNND2,LSAMP,GPM6A,NKAIN3
2.046e-04	-8.49	YWHAG (tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein gamma)	protein interactions	7532	1211	11	19454	50	ABLIM1,FMN2,MACF1,PRKCA,DCLK2,NHSL1,PARD3,PARD3B,SASH1,SORBS1,PITPNC1
2.098e-04	-8.47	bone	COSMIC cancer mutations	bone	8157	37	16828	50	ITPR2,ZBTB20,GLIS3,SORBS1,SLC4A4,FMN2,SLC1A3,ADCY2,PARD3,QKI,CSGALNACT1,TRPS1,LIFR,NEBL,RORA,NRG3,RYR3,PARD3B,SOX5,GPM6A,DCLK2,DTNA,MAML2,PPP2R2B,LSAMP,PTPRZ1,NTRK2,CTNND2,GPC5,ABLIM1,NPAS3,MACF1,SASH1,ATP13A4,SPARCL1,TRPM3,NKAIN3
2.122e-04	-8.46	Pancreatic secretion	KEGG pathways	hsa04972	95	4	7161	23	SLC4A4,ITPR2,ADCY2,PRKCA
2.122e-04	-8.46	Pancreatic secretion	KEGG pathways	ko04972	95	4	7161	23	ADCY2,PRKCA,ITPR2,SLC4A4
2.132e-04	-8.45	lung-left_upper_lobe-carcinoma-adenocarcinoma	COSMIC cancer mutations	lung-left_upper_lobe-carcinoma-adenocarcinoma	556	8	16828	50	ADCY2,SLC4A4,LIFR,CTNND2,TRPS1,FBXL7,NTRK2,RYR3
2.185e-04	-8.43	left_upper_lobe	COSMIC cancer mutations	left_upper_lobe	558	8	16828	50	LIFR,SLC4A4,TRPS1,CTNND2,ADCY2,NTRK2,RYR3,FBXL7
2.276e-04	-8.39	monoatomic cation transmembrane transporter activity	molecular function	GO:0008324	630	8	18094	48	RYR3,TRPM3,SLC1A3,SLC4A4,ITPR2,ATP13A4,GPM6A,SLC1A2
2.295e-04	-8.38	NA_DICARBOXYL_SYMP_1	prosite domains	PS00713	7	2	12186	41	SLC1A3,SLC1A2
2.295e-04	-8.38	NA_DICARBOXYL_SYMP_2	prosite domains	PS00714	7	2	12186	41	SLC1A3,SLC1A2
2.304e-04	-8.38	LSAMP (limbic system associated membrane protein)	protein interactions	4045	9	2	19454	50	LSAMP,NTM
2.304e-04	-8.38	NEGR1 (neuronal growth regulator 1)	protein interactions	257194	9	2	19454	50	NTM,LSAMP
2.551e-04	-8.27	acidic amino acid transport	biological process	GO:0015800	45	3	18204	50	SLC1A3,NTRK2,SLC1A2
2.564e-04	-8.27	OCLN (occludin)	protein interactions	100506658	495	7	19454	50	PARD3,NTRK2,ABLIM1,FMN2,MACF1,PRKCA,DTNA
2.594e-04	-8.26	calcium channel activity	molecular function	GO:0005262	117	4	18094	48	ITPR2,RYR3,TRPM3,GPM6A
2.643e-04	-8.24	central_nervous_system-cerebellum-glioma-astrocytoma_Grade_I	COSMIC cancer mutations	central_nervous_system-cerebellum-glioma-astrocytoma_Grade_I	105	4	16828	50	GPC5,PARD3,NRG3,QKI
2.704e-04	-8.22	PLC beta mediated events	REACTOME pathways	R-HSA-112043	47	3	10285	28	ITPR2,ADCY2,PRKCA
2.880e-04	-8.15	G-protein mediated events	REACTOME pathways	R-HSA-112040	48	3	10285	28	PRKCA,ADCY2,ITPR2
2.888e-04	-8.15	EDTRNSPORT	prints domains	PR00173	7	2	5227	20	SLC1A2,SLC1A3
3.074e-04	-8.09	cell junction	cellular component	GO:0030054	2224	15	19108	49	CTNND2,GPM6A,NFIA,QKI,SLC1A3,PTPRZ1,SPARCL1,CDH20,DTNA,SLC1A2,PARD3B,PARD3,NTRK2,SORBS1,NRG3
3.101e-04	-8.08	skin-trunk-malignant_melanoma-nodular	COSMIC cancer mutations	skin-trunk-malignant_melanoma-nodular	1291	12	16828	50	ATP13A4,CDH20,PTPRZ1,NTRK2,SPARCL1,ABLIM1,GLIS3,NPAS3,DCLK2,CTNND2,MACF1,NEBL
3.141e-04	-8.07	haematopoietic_and_lymphoid_tissue-lymph_node-lymphoid_neoplasm-diffuse_large_B_cell_lymphoma	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue-lymph_node-lymphoid_neoplasm-diffuse_large_B_cell_lymphoma	748	9	16828	50	SLC1A3,NEBL,ITPR2,CTNND2,TRPS1,DTNA,PARD3,SOX5,NTRK2
3.162e-04	-8.06	EPB41L4A (erythrocyte membrane protein band 4.1 like 4A)	protein interactions	64097	127	4	19454	50	MACF1,PARD3,ABLIM1,DTNA
3.162e-04	-8.06	MIR	pfam domains	PF02815	10	2	17795	48	ITPR2,RYR3
3.165e-04	-8.06	central nervous system development	biological process	GO:0007417	995	10	18204	50	DCLK2,QKI,SLC1A2,RFX4,RORA,NTRK2,BMPR1B,MSI2,NRG3,PTPRZ1
3.170e-04	-8.06	MIR_motif	interpro domains	IPR016093	10	2	18521	50	ITPR2,RYR3
3.170e-04	-8.06	MIR_dom_sf	interpro domains	IPR036300	10	2	18521	50	ITPR2,RYR3
3.226e-04	-8.04	Transmembrane transport of small molecules	REACTOME pathways	R-HSA-382551	677	8	10285	28	AQP4,SLC1A2,TRPM3,RYR3,ADCY2,SLC4A4,SLC1A3,ATP13A4
3.233e-04	-8.04	pancreas-carcinoid-endocrine_tumour	COSMIC cancer mutations	pancreas-carcinoid-endocrine_tumour	7250	34	16828	50	SOX5,RYR3,GPM6A,FBXL7,LIFR,NRG3,RORA,NEBL,CDH20,RFX4,CSGALNACT1,QKI,PARD3,SLC4A4,ITPR2,GLIS3,SLC1A3,ADCY2,FMN2,ATP13A4,NKAIN3,MACF1,ABLIM1,GPC5,CTNND2,SASH1,NHSL1,NTRK2,SLC1A2,BMPR1B,PRKCA,MAML2,LSAMP,PPP2R2B
3.281e-04	-8.02	positive regulation of lipopolysaccharide-mediated signaling pathway	biological process	GO:0031666	10	2	18204	50	SASH1,PRKCA
3.281e-04	-8.02	establishment of centrosome localization	biological process	GO:0051660	10	2	18204	50	PARD3,PARD3B
3.281e-04	-8.02	cellular response to cocaine	biological process	GO:0071314	10	2	18204	50	SLC1A3,SLC1A2
3.283e-04	-8.02	glial cell differentiation	biological process	GO:0010001	219	5	18204	50	PTPRZ1,NFIA,QKI,NTRK2,PARD3
3.354e-04	-8.00	MARK3 (microtubule affinity regulating kinase 3)	protein interactions	4140	235	5	19454	50	PARD3,MACF1,NTRK2,PPP2R2B,DTNA
3.508e-04	-7.96	ADCY5 (adenylate cyclase 5)	protein interactions	111	11	2	19454	50	PRKCA,ADCY2
3.553e-04	-7.94	central_nervous_system-brain-primitive_neuroectodermal_tumour-medulloblastoma-large_cell	COSMIC cancer mutations	central_nervous_system-brain-primitive_neuroectodermal_tumour-medulloblastoma-large_cell	1117	11	16828	50	ADCY2,FMN2,NRG3,GPC5,PARD3,QKI,SLC1A2,RYR3,ATP13A4,SOX5,CDH20
3.654e-04	-7.91	haematopoietic_and_lymphoid_tissue	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue	14368	50	16828	50	BMPR1B,PRKCA,DCLK2,LSAMP,PPP2R2B,ATP13A4,NPAS3,GPC5,CTNND2,SASH1,CDH20,RFX4,CSGALNACT1,QKI,MSI2,TRPS1,NRG3,NEBL,NTRK2,PTPRZ1,SLC1A2,MAML2,DTNA,AQP4,NKAIN3,NFIA,TRPM3,SPARCL1,MACF1,ABLIM1,NTM,NHSL1,PARD3,SLC4A4,SORBS1,ITPR2,ZBTB20,GLIS3,ADCY2,FMN2,SLC1A3,SOX5,PARD3B,RYR3,GPM6A,MGAT4C,FBXL7,LIFR,RORA,PITPNC1
3.669e-04	-7.91	YWHAH (tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein eta)	protein interactions	7533	1083	10	19454	50	MACF1,FMN2,ABLIM1,NHSL1,DCLK2,PARD3,PARD3B,SASH1,PITPNC1,SORBS1
3.988e-04	-7.83	NTRK2 (neurotrophic receptor tyrosine kinase 2)	protein interactions	4915	135	4	19454	50	NTRK2,ABLIM1,PARD3,DTNA
4.003e-04	-7.82	L-glutamate import across plasma membrane	biological process	GO:0098712	11	2	18204	50	SLC1A2,SLC1A3
4.003e-04	-7.82	L-aspartate transmembrane transport	biological process	GO:0070778	11	2	18204	50	SLC1A3,SLC1A2
4.117e-04	-7.80	anatomical structure development	biological process	GO:0048856	5207	26	18204	50	FMN2,ABLIM1,LSAMP,PTPRZ1,CTNND2,RORA,NTRK2,SLC1A2,NEBL,DCLK2,NFIA,PARD3,CDH20,NTM,TRPS1,GPM6A,NRG3,CSGALNACT1,BMPR1B,PRKCA,MSI2,QKI,SLC1A3,SPARCL1,RFX4,SOX5
4.146e-04	-7.79	regulation of chondrocyte differentiation	biological process	GO:0032330	53	3	18204	50	TRPS1,BMPR1B,SOX5
4.172e-04	-7.78	autonomic_ganglia-neuroblastoma	COSMIC cancer mutations	autonomic_ganglia-neuroblastoma	3970	23	16828	50	MAML2,NTRK2,SLC1A2,PTPRZ1,SASH1,MACF1,CTNND2,NPAS3,NFIA,AQP4,ADCY2,FMN2,SLC4A4,GLIS3,PARD3,RFX4,PITPNC1,NEBL,TRPS1,GPM6A,FBXL7,RYR3,PARD3B
4.188e-04	-7.78	neuroblastoma	COSMIC cancer mutations	neuroblastoma	3971	23	16828	50	MAML2,PTPRZ1,SLC1A2,NTRK2,SASH1,CTNND2,NPAS3,MACF1,NFIA,AQP4,FMN2,ADCY2,GLIS3,SLC4A4,PARD3,RFX4,NEBL,PITPNC1,TRPS1,FBXL7,GPM6A,RYR3,PARD3B
4.598e-04	-7.68	calcium ion transmembrane transporter activity	molecular function	GO:0015085	136	4	18094	48	RYR3,ITPR2,GPM6A,TRPM3
4.874e-04	-7.63	neuron development	biological process	GO:0048666	859	9	18204	50	BMPR1B,NTRK2,PTPRZ1,CTNND2,PARD3,NTM,DCLK2,SLC1A3,GPM6A
4.886e-04	-7.62	MIR	prosite domains	PS50919	10	2	12186	41	RYR3,ITPR2
5.213e-04	-7.56	cell morphogenesis	biological process	GO:0000902	687	8	18204	50	CDH20,PARD3,NFIA,GPM6A,SLC1A3,BMPR1B,CTNND2,PTPRZ1
5.266e-04	-7.55	inorganic molecular entity transmembrane transporter activity	molecular function	GO:0015318	714	8	18094	48	SLC1A3,ITPR2,SLC4A4,SLC1A2,GPM6A,AQP4,RYR3,TRPM3
5.318e-04	-7.54	upper_aerodigestive_tract	COSMIC cancer mutations	upper_aerodigestive_tract	13181	48	16828	50	ADCY2,SLC1A3,FMN2,ITPR2,ZBTB20,GLIS3,SLC4A4,SORBS1,PARD3,PITPNC1,RORA,LIFR,FBXL7,MGAT4C,GPM6A,RYR3,SOX5,PARD3B,DTNA,MAML2,PTPRZ1,SLC1A2,NTRK2,NHSL1,NTM,ABLIM1,MACF1,TRPM3,NFIA,NKAIN3,MSI2,QKI,CSGALNACT1,RFX4,CDH20,NEBL,NRG3,TRPS1,PPP2R2B,LSAMP,DCLK2,PRKCA,BMPR1B,SASH1,GPC5,CTNND2,NPAS3,ATP13A4
5.450e-04	-7.51	basal_(triple-negative)_carcinoma	COSMIC cancer mutations	basal_(triple-negative)_carcinoma	2981	19	16828	50	NTM,NPAS3,MACF1,LIFR,NEBL,SASH1,NRG3,SPARCL1,TRPM3,MAML2,SLC4A4,PRKCA,PPP2R2B,MSI2,ADCY2,FMN2,NTRK2,PARD3,BMPR1B
5.450e-04	-7.51	breast-carcinoma-basal_(triple-negative)_carcinoma	COSMIC cancer mutations	breast-carcinoma-basal_(triple-negative)_carcinoma	2981	19	16828	50	LIFR,MACF1,NTM,NPAS3,NRG3,SASH1,NEBL,TRPM3,SPARCL1,PRKCA,MAML2,SLC4A4,FMN2,MSI2,ADCY2,PPP2R2B,NTRK2,BMPR1B,PARD3
5.688e-04	-7.47	Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour	COSMIC cancer mutations	Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour	7434	34	16828	50	ABLIM1,NPAS3,CTNND2,MACF1,SASH1,ATP13A4,TRPM3,SPARCL1,NKAIN3,DCLK2,DTNA,MAML2,PPP2R2B,PTPRZ1,NTRK2,TRPS1,LIFR,NEBL,NRG3,RORA,PARD3B,SOX5,RYR3,GLIS3,ZBTB20,ITPR2,SORBS1,SLC4A4,SLC1A3,FMN2,ADCY2,PARD3,CSGALNACT1,QKI
6.145e-04	-7.39	L-glutamate transmembrane transporter activity	molecular function	GO:0005313	14	2	18094	48	SLC1A2,SLC1A3
6.228e-04	-7.38	MIR	smart domains	SM00472	10	2	9717	37	RYR3,ITPR2
6.831e-04	-7.29	stomach-adenocarcinoma	COSMIC cancer mutations	stomach-adenocarcinoma	4101	23	16828	50	MGAT4C,ATP13A4,PARD3B,NEBL,RORA,SASH1,NRG3,CTNND2,TRPS1,GPC5,ABLIM1,MACF1,PARD3,QKI,CSGALNACT1,RFX4,SLC1A2,CDH20,PPP2R2B,FMN2,ITPR2,SLC4A4,PRKCA
6.998e-04	-7.26	YWHAB (tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein beta)	protein interactions	7529	965	9	19454	50	ABLIM1,MACF1,DCLK2,NHSL1,SASH1,PARD3B,PARD3,SORBS1,PITPNC1
7.405e-04	-7.21	monoatomic ion transmembrane transporter activity	molecular function	GO:0015075	752	8	18094	48	GPM6A,SLC1A2,ITPR2,SLC4A4,ATP13A4,SLC1A3,TRPM3,RYR3
7.476e-04	-7.20	developmental process	biological process	GO:0032502	5716	27	18204	50	NRG3,CSGALNACT1,BMPR1B,PRKCA,MSI2,GPM6A,SPARCL1,RFX4,SOX5,QKI,SLC1A3,PTPRZ1,NHSL1,CTNND2,RORA,SLC1A2,NTRK2,NEBL,FMN2,ABLIM1,LSAMP,TRPS1,DCLK2,NFIA,PARD3,NTM,CDH20
7.585e-04	-7.18	upper_aerodigestive_tract-pharynx-carcinoma-nasopharyngeal_carcinoma	COSMIC cancer mutations	upper_aerodigestive_tract-pharynx-carcinoma-nasopharyngeal_carcinoma	1425	12	16828	50	ATP13A4,NFIA,CTNND2,PITPNC1,NHSL1,NTRK2,RFX4,SLC1A2,QKI,PRKCA,SLC4A4,FMN2
7.585e-04	-7.18	nasopharyngeal_carcinoma	COSMIC cancer mutations	nasopharyngeal_carcinoma	1425	12	16828	50	FMN2,PRKCA,SLC4A4,QKI,NTRK2,SLC1A2,RFX4,PITPNC1,NHSL1,CTNND2,NFIA,ATP13A4
7.647e-04	-7.18	astrocytoma_Grade_I	COSMIC cancer mutations	astrocytoma_Grade_I	139	4	16828	50	GPC5,QKI,NRG3,PARD3
8.086e-04	-7.12	human chr3q13.31	chromosome location	human chr3q13.31	22	2	26134	50	ZBTB20,LSAMP
8.160e-04	-7.11	rhabdomyosarcoma	COSMIC cancer mutations	rhabdomyosarcoma	4150	23	16828	50	RORA,TRPS1,RYR3,PARD3B,FMN2,ADCY2,SLC1A3,GLIS3,SORBS1,PARD3,CDH20,NHSL1,SASH1,CTNND2,NPAS3,MACF1,SPARCL1,TRPM3,NFIA,AQP4,PPP2R2B,MAML2,PTPRZ1
8.237e-04	-7.10	haematopoietic_and_lymphoid_tissue-haematopoietic_neoplasm-mast_cell_neoplasm	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue-haematopoietic_neoplasm-mast_cell_neoplasm	248	5	16828	50	GPC5,NPAS3,ADCY2,NFIA,NRG3
8.237e-04	-7.10	mast_cell_neoplasm	COSMIC cancer mutations	mast_cell_neoplasm	248	5	16828	50	NPAS3,GPC5,NRG3,NFIA,ADCY2
8.309e-04	-7.09	PARD3 (par-3 family cell polarity regulator)	protein interactions	56288	287	5	19454	50	DTNA,SORBS1,NTRK2,PARD3,PARD3B
8.440e-04	-7.08	VASP (vasodilator stimulated phosphoprotein)	protein interactions	7408	288	5	19454	50	NHSL1,SORBS1,NEBL,FMN2,PARD3
8.632e-04	-7.05	inorganic cation transmembrane transporter activity	molecular function	GO:0022890	589	7	18094	48	TRPM3,RYR3,GPM6A,SLC1A2,SLC1A3,ITPR2,SLC4A4
8.657e-04	-7.05	asymmetric cell division	biological process	GO:0008356	16	2	18204	50	SOX5,PARD3
8.667e-04	-7.05	scalp	COSMIC cancer mutations	scalp	2110	15	16828	50	PTPRZ1,SORBS1,SLC4A4,PPP2R2B,FMN2,LSAMP,SOX5,ATP13A4,NFIA,MACF1,TRPS1,GPC5,NTM,RORA,NEBL
8.795e-04	-7.04	retina development in camera-type eye	biological process	GO:0060041	156	4	18204	50	NFIA,GPM6A,BMPR1B,NTRK2
9.223e-04	-6.99	gliogenesis	biological process	GO:0042063	275	5	18204	50	PTPRZ1,QKI,NFIA,PARD3,NTRK2
9.374e-04	-6.97	telencephalon development	biological process	GO:0021537	276	5	18204	50	NRG3,DCLK2,SLC1A2,NTRK2,RFX4
9.444e-04	-6.96	cell adhesion	biological process	GO:0007155	942	9	18204	50	PRKCA,CTNND2,SPARCL1,LSAMP,NTM,CDH20,PARD3,SORBS1,PARD3B
1.015e-03	-6.89	lung-carcinoma-squamous_cell_carcinoma	COSMIC cancer mutations	lung-carcinoma-squamous_cell_carcinoma	14664	50	16828	50	SLC1A3,FMN2,ADCY2,ITPR2,ZBTB20,GLIS3,SORBS1,SLC4A4,PARD3,PITPNC1,RORA,LIFR,FBXL7,MGAT4C,GPM6A,SOX5,PARD3B,RYR3,DTNA,MAML2,SLC1A2,PTPRZ1,NTRK2,NHSL1,NTM,ABLIM1,MACF1,TRPM3,SPARCL1,NKAIN3,NFIA,AQP4,MSI2,CSGALNACT1,QKI,CDH20,RFX4,NEBL,NRG3,TRPS1,LSAMP,PPP2R2B,DCLK2,PRKCA,BMPR1B,SASH1,NPAS3,GPC5,CTNND2,ATP13A4
1.022e-03	-6.89	Htt (huntingtin)	protein interactions	15194	77	3	19454	50	NTM,LSAMP,GPM6A
1.026e-03	-6.88	acidic amino acid transmembrane transporter activity	molecular function	GO:0015172	18	2	18094	48	SLC1A3,SLC1A2
1.026e-03	-6.88	intracellularly gated calcium channel activity	molecular function	GO:0015278	18	2	18094	48	RYR3,ITPR2
1.047e-03	-6.86	prostate-carcinoma-adenocarcinoma	COSMIC cancer mutations	prostate-carcinoma-adenocarcinoma	12379	46	16828	50	CDH20,RFX4,CSGALNACT1,QKI,TRPS1,NRG3,NEBL,BMPR1B,PRKCA,LSAMP,PPP2R2B,ATP13A4,NPAS3,CTNND2,GPC5,SASH1,PARD3,SORBS1,GLIS3,ITPR2,ZBTB20,SLC1A3,FMN2,ADCY2,PARD3B,SOX5,RYR3,GPM6A,FBXL7,MGAT4C,LIFR,RORA,PITPNC1,NTRK2,PTPRZ1,SLC1A2,MAML2,AQP4,NKAIN3,NFIA,TRPM3,SPARCL1,MACF1,NTM,ABLIM1,NHSL1
1.049e-03	-6.86	HNRNPL (heterogeneous nuclear ribonucleoprotein L)	protein interactions	3191	1958	13	19454	50	DTNA,ABLIM1,MACF1,ZBTB20,PARD3B,QKI,DCLK2,TRPS1,NFIA,NRG3,BMPR1B,MSI2,PARD3
1.053e-03	-6.86	LCK (LCK proto-oncogene, Src family tyrosine kinase)	protein interactions	3932	455	6	19454	50	MACF1,PARD3,FMN2,PRKCA,CTNND2,DTNA
1.059e-03	-6.85	regulation of cartilage development	biological process	GO:0061035	73	3	18204	50	TRPS1,BMPR1B,SOX5
1.071e-03	-6.84	astrocyte projection	cellular component	GO:0097449	19	2	19108	49	SLC1A2,AQP4
1.075e-03	-6.84	striated_muscle	COSMIC cancer mutations	striated_muscle	4228	23	16828	50	SPARCL1,TRPM3,NFIA,RYR3,PARD3B,AQP4,NHSL1,RORA,SASH1,TRPS1,CTNND2,NPAS3,MACF1,PARD3,PTPRZ1,CDH20,PPP2R2B,FMN2,SLC1A3,ADCY2,GLIS3,SORBS1,MAML2
1.077e-03	-6.83	OSM (oncostatin M)	protein interactions	5008	19	2	19454	50	LIFR,TRPM3
1.096e-03	-6.82	transporter activity	molecular function	GO:0005215	1211	10	18094	48	TRPM3,RYR3,AQP4,PITPNC1,GPM6A,SLC1A2,ATP13A4,SLC4A4,ITPR2,SLC1A3
1.100e-03	-6.81	multicellular organismal process	biological process	GO:0032501	6177	28	18204	50	RYR3,CTNND2,PTPRZ1,NTRK2,SLC1A2,RORA,NEBL,ABLIM1,LSAMP,TRPS1,NFIA,DCLK2,CDH20,NTM,PARD3,DTNA,NRG3,PRKCA,MSI2,CSGALNACT1,BMPR1B,GPM6A,AQP4,SOX5,RFX4,SLC4A4,QKI,SLC1A3
1.124e-03	-6.79	skin-trunk-malignant_melanoma	COSMIC cancer mutations	skin-trunk-malignant_melanoma	2647	17	16828	50	MGAT4C,SOX5,ATP13A4,RYR3,NEBL,NRG3,SASH1,TRPS1,CTNND2,LIFR,PARD3,CDH20,PTPRZ1,LSAMP,SLC1A3,PPP2R2B,MAML2
1.127e-03	-6.79	large_intestine-adenoma	COSMIC cancer mutations	large_intestine-adenoma	266	5	16828	50	SOX5,CDH20,RYR3,LIFR,SASH1
1.171e-03	-6.75	MYOD1 (myogenic differentiation 1)	protein interactions	4654	180	4	19454	50	PRKCA,RORA,TRPS1,NFIA
1.172e-03	-6.75	C11orf52 (chromosome 11 open reading frame 52)	protein interactions	91894	310	5	19454	50	ABLIM1,FMN2,PARD3,MACF1,DTNA
1.186e-03	-6.74	haematopoietic_neoplasm	COSMIC cancer mutations	haematopoietic_neoplasm	11082	43	16828	50	SOX5,PARD3B,RYR3,FBXL7,LIFR,NRG3,RORA,NEBL,CDH20,RFX4,CSGALNACT1,QKI,PARD3,SLC4A4,GLIS3,ITPR2,SLC1A3,ADCY2,FMN2,MSI2,ATP13A4,NKAIN3,NFIA,TRPM3,SPARCL1,MACF1,NTM,ABLIM1,NPAS3,CTNND2,GPC5,SASH1,NHSL1,NTRK2,SLC1A2,PTPRZ1,BMPR1B,PRKCA,MAML2,DCLK2,DTNA,LSAMP,PPP2R2B
1.187e-03	-6.74	alveolar	COSMIC cancer mutations	alveolar	2414	16	16828	50	SORBS1,FMN2,SLC1A3,PPP2R2B,CDH20,PARD3,NPAS3,TRPS1,MACF1,NHSL1,SASH1,PARD3B,RYR3,TRPM3,SPARCL1,NFIA
1.187e-03	-6.74	soft_tissue-striated_muscle-rhabdomyosarcoma-alveolar	COSMIC cancer mutations	soft_tissue-striated_muscle-rhabdomyosarcoma-alveolar	2414	16	16828	50	CDH20,PARD3,SORBS1,PPP2R2B,FMN2,SLC1A3,RYR3,PARD3B,NFIA,SPARCL1,TRPM3,MACF1,TRPS1,NPAS3,SASH1,NHSL1
1.226e-03	-6.70	GSC (goosecoid homeobox)	protein interactions	145258	82	3	19454	50	SOX5,NFIA,TRPS1
1.227e-03	-6.70	cartilage condensation	biological process	GO:0001502	19	2	18204	50	SOX5,BMPR1B
1.247e-03	-6.69	solute:sodium symporter activity	molecular function	GO:0015370	80	3	18094	48	SLC4A4,SLC1A3,SLC1A2
1.261e-03	-6.68	Oxytocin signaling pathway	KEGG pathways	ko04921	152	4	7161	23	ADCY2,PRKCA,ITPR2,RYR3
1.261e-03	-6.68	Oxytocin signaling pathway	KEGG pathways	hsa04921	152	4	7161	23	ADCY2,PRKCA,ITPR2,RYR3
1.283e-03	-6.66	dicarboxylic acid transport	biological process	GO:0006835	78	3	18204	50	SLC1A3,SLC1A2,NTRK2
1.283e-03	-6.66	positive regulation of carbohydrate metabolic process	biological process	GO:0045913	78	3	18204	50	SLC4A4,SORBS1,ZBTB20
1.290e-03	-6.65	cartilage development	biological process	GO:0051216	173	4	18204	50	BMPR1B,CSGALNACT1,SOX5,NFIA
1.318e-03	-6.63	TENM1 (teneurin transmembrane protein 1)	protein interactions	10178	21	2	19454	50	SORBS1,MACF1
1.335e-03	-6.62	ovary-carcinoma-serous_carcinoma	COSMIC cancer mutations	ovary-carcinoma-serous_carcinoma	10710	42	16828	50	MACF1,CTNND2,GPC5,NTM,NPAS3,SASH1,NHSL1,ATP13A4,TRPM3,MAML2,PRKCA,DTNA,DCLK2,PPP2R2B,LSAMP,NTRK2,PTPRZ1,SLC1A2,BMPR1B,LIFR,TRPS1,RORA,NRG3,NEBL,RYR3,SOX5,PARD3B,MGAT4C,FBXL7,SLC4A4,SORBS1,ITPR2,GLIS3,ZBTB20,ADCY2,SLC1A3,MSI2,FMN2,CDH20,QKI,CSGALNACT1,PARD3
1.357e-03	-6.60	plasma membrane bounded cell projection	cellular component	GO:0120025	2285	14	19108	49	PARD3,GPM6A,DTNA,CTNND2,ADCY2,MACF1,SLC1A2,BMPR1B,SLC1A3,ABLIM1,PRKCA,FMN2,AQP4,NTRK2
1.361e-03	-6.60	positive regulation of chondrocyte differentiation	biological process	GO:0032332	20	2	18204	50	SOX5,BMPR1B
1.361e-03	-6.60	aspartate transmembrane transport	biological process	GO:0015810	20	2	18204	50	SLC1A3,SLC1A2
1.364e-03	-6.60	superficial_spreading	COSMIC cancer mutations	superficial_spreading	1110	10	16828	50	MGAT4C,ATP13A4,PPP2R2B,ADCY2,CTNND2,NTM,MACF1,SLC4A4,SORBS1,LIFR
1.375e-03	-6.59	central nervous system neuron differentiation	biological process	GO:0021953	176	4	18204	50	DCLK2,RORA,NTRK2,BMPR1B
1.397e-03	-6.57	contractile actin filament bundle	cellular component	GO:0097517	86	3	19108	49	ABLIM1,SORBS1,NEBL
1.397e-03	-6.57	stress fiber	cellular component	GO:0001725	86	3	19108	49	NEBL,SORBS1,ABLIM1
1.435e-03	-6.55	Bile secretion	KEGG pathways	hsa04976	71	3	7161	23	ADCY2,AQP4,SLC4A4
1.435e-03	-6.55	Bile secretion	KEGG pathways	ko04976	71	3	7161	23	ADCY2,AQP4,SLC4A4
1.446e-03	-6.54	monoatomic ion transmembrane transport	biological process	GO:0034220	804	8	18204	50	RYR3,TRPM3,SLC1A2,SLC4A4,ATP13A4,GPM6A,SLC1A3,ITPR2
1.502e-03	-6.50	positive regulation of glycolytic process	biological process	GO:0045821	21	2	18204	50	ZBTB20,SLC4A4
1.502e-03	-6.50	cell aggregation	biological process	GO:0098743	21	2	18204	50	BMPR1B,SOX5
1.502e-03	-6.50	positive regulation of nucleotide catabolic process	biological process	GO:0030813	21	2	18204	50	ZBTB20,SLC4A4
1.502e-03	-6.50	positive regulation of purine nucleotide catabolic process	biological process	GO:0033123	21	2	18204	50	ZBTB20,SLC4A4
1.508e-03	-6.50	YWHAQ (tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein theta)	protein interactions	10971	1076	9	19454	50	PRKCA,ABLIM1,MACF1,DCLK2,NHSL1,SASH1,PARD3B,PARD3,SORBS1
1.537e-03	-6.48	Opioid Signalling	REACTOME pathways	R-HSA-111885	85	3	10285	28	PRKCA,ADCY2,ITPR2
1.582e-03	-6.45	Rbm38 (RNA binding motif protein 38)	protein interactions	56190	23	2	19454	50	QKI,MSI2
1.587e-03	-6.45	regulation of carbohydrate metabolic process	biological process	GO:0006109	183	4	18204	50	SLC4A4,RORA,ZBTB20,SORBS1
1.596e-03	-6.44	SHC1 events in ERBB2 signaling	REACTOME pathways	R-HSA-1250196	22	2	10285	28	NRG3,PRKCA
1.617e-03	-6.43	Thyroid hormone synthesis	KEGG pathways	hsa04918	74	3	7161	23	PRKCA,ADCY2,ITPR2
1.617e-03	-6.43	Thyroid hormone synthesis	KEGG pathways	ko04918	74	3	7161	23	PRKCA,ADCY2,ITPR2
1.632e-03	-6.42	cellular response to organic cyclic compound	biological process	GO:0071407	464	6	18204	50	RORA,SLC1A2,ADCY2,RYR3,ITPR2,SLC1A3
1.650e-03	-6.41	mucosal	COSMIC cancer mutations	mucosal	2009	14	16828	50	PPP2R2B,FMN2,SORBS1,PARD3,BMPR1B,NEBL,RORA,NRG3,CTNND2,ABLIM1,LIFR,SPARCL1,MGAT4C,ATP13A4
1.650e-03	-6.41	skin-mucosal-malignant_melanoma	COSMIC cancer mutations	skin-mucosal-malignant_melanoma	2009	14	16828	50	PARD3,BMPR1B,SORBS1,FMN2,PPP2R2B,ATP13A4,SPARCL1,MGAT4C,ABLIM1,CTNND2,LIFR,NEBL,NRG3,RORA
1.664e-03	-6.40	monoatomic cation transmembrane transport	biological process	GO:0098655	636	7	18204	50	SLC4A4,TRPM3,RYR3,ITPR2,ATP13A4,SLC1A3,GPM6A
1.681e-03	-6.39	Gastric acid secretion	KEGG pathways	ko04971	75	3	7161	23	ITPR2,ADCY2,PRKCA
1.681e-03	-6.39	Gastric acid secretion	KEGG pathways	hsa04971	75	3	7161	23	ITPR2,ADCY2,PRKCA
1.683e-03	-6.39	amino acid:sodium symporter activity	molecular function	GO:0005283	23	2	18094	48	SLC1A2,SLC1A3
1.695e-03	-6.38	actomyosin	cellular component	GO:0042641	92	3	19108	49	NEBL,SORBS1,ABLIM1
1.700e-03	-6.38	vascular transport	biological process	GO:0010232	86	3	18204	50	SLC1A3,SLC4A4,SLC1A2
1.700e-03	-6.38	transport across blood-brain barrier	biological process	GO:0150104	86	3	18204	50	SLC1A2,SLC4A4,SLC1A3
1.706e-03	-6.37	oesophagus-middle_third-carcinoma-squamous_cell_carcinoma	COSMIC cancer mutations	oesophagus-middle_third-carcinoma-squamous_cell_carcinoma	3531	20	16828	50	ZBTB20,SLC4A4,MAML2,ADCY2,FMN2,PTPRZ1,PARD3,GPC5,CTNND2,ABLIM1,MACF1,NHSL1,NEBL,SASH1,NRG3,RYR3,SOX5,SPARCL1,TRPM3,GPM6A
1.715e-03	-6.37	human chr17q24.2	chromosome location	human chr17q24.2	32	2	26134	50	PITPNC1,PRKCA
1.718e-03	-6.37	middle_third	COSMIC cancer mutations	middle_third	3533	20	16828	50	SOX5,RYR3,TRPM3,SPARCL1,GPM6A,ABLIM1,GPC5,CTNND2,MACF1,NEBL,NHSL1,NRG3,SASH1,PTPRZ1,PARD3,ZBTB20,SLC4A4,MAML2,ADCY2,FMN2
1.757e-03	-6.34	TIAM1 (TIAM Rac1 associated GEF 1)	protein interactions	7074	201	4	19454	50	DTNA,RYR3,PARD3,PRKCA
1.901e-03	-6.27	Glutamate Neurotransmitter Release Cycle	REACTOME pathways	R-HSA-210500	24	2	10285	28	SLC1A2,SLC1A3
1.913e-03	-6.26	human chr6q24.3-q25.1	chromosome location	human chr6q24.3-q25.1	1	1	26134	50	SASH1
1.913e-03	-6.26	human chr12q21.31-q21.32	chromosome location	human chr12q21.31-q21.32	1	1	26134	50	MGAT4C
1.913e-03	-6.26	human chr4q31.23-q31.3	chromosome location	human chr4q31.23-q31.3	1	1	26134	50	DCLK2
1.913e-03	-6.26	human chr10p11.22-p11.21	chromosome location	human chr10p11.22-p11.21	1	1	26134	50	PARD3
1.913e-03	-6.26	human chr9q21.12-q21.13	chromosome location	human chr9q21.12-q21.13	1	1	26134	50	TRPM3
1.913e-03	-6.26	human chr15q13.3-q14	chromosome location	human chr15q13.3-q14	1	1	26134	50	RYR3
1.915e-03	-6.26	actin filament bundle	cellular component	GO:0032432	96	3	19108	49	SORBS1,ABLIM1,NEBL
2.027e-03	-6.20	skin-head_neck-carcinoma-squamous_cell_carcinoma	COSMIC cancer mutations	skin-head_neck-carcinoma-squamous_cell_carcinoma	14191	49	16828	50	CDH20,RFX4,CSGALNACT1,QKI,TRPS1,NEBL,NRG3,DCLK2,PRKCA,LSAMP,PPP2R2B,BMPR1B,NPAS3,CTNND2,GPC5,SASH1,ATP13A4,GLIS3,ZBTB20,ITPR2,SLC4A4,SORBS1,ADCY2,FMN2,SLC1A3,PARD3,LIFR,PITPNC1,RORA,PARD3B,SOX5,RYR3,FBXL7,MGAT4C,GPM6A,DTNA,MAML2,PTPRZ1,SLC1A2,NTRK2,NTM,ABLIM1,MACF1,NHSL1,AQP4,TRPM3,SPARCL1,NKAIN3,NFIA
2.047e-03	-6.19	FRS2 (fibroblast growth factor receptor substrate 2)	protein interactions	10818	98	3	19454	50	PARD3,NTRK2,SORBS1
2.062e-03	-6.18	protein tetramerization	biological process	GO:0051262	92	3	18204	50	RYR3,AQP4,TRPM3
2.077e-03	-6.18	Axon guidance	KEGG pathways	ko04360	174	4	7161	23	ABLIM1,PRKCA,BMPR1B,PARD3
2.077e-03	-6.18	Axon guidance	KEGG pathways	hsa04360	174	4	7161	23	ABLIM1,PRKCA,BMPR1B,PARD3
2.130e-03	-6.15	L-glutamate transmembrane transport	biological process	GO:0015813	25	2	18204	50	SLC1A2,SLC1A3
2.134e-03	-6.15	Calcium Regulation in the Cardiac Cell	WikiPathways	WP536	151	4	5310	20	PRKCA,RYR3,ADCY2,ITPR2
2.146e-03	-6.14	synapse organization	biological process	GO:0050808	333	5	18204	50	NRG3,SPARCL1,NFIA,CTNND2,GPM6A
2.161e-03	-6.14	cell projection	cellular component	GO:0042995	2398	14	19108	49	SLC1A2,MACF1,CTNND2,ADCY2,DTNA,GPM6A,PARD3,NTRK2,AQP4,FMN2,PRKCA,SLC1A3,ABLIM1,BMPR1B
2.170e-03	-6.13	cell development	biological process	GO:0048468	2236	14	18204	50	NTM,PARD3,QKI,SLC1A3,DCLK2,MSI2,NEBL,BMPR1B,RORA,NTRK2,CTNND2,PTPRZ1,GPM6A,FMN2
2.173e-03	-6.13	Aldosterone synthesis and secretion	KEGG pathways	ko04925	82	3	7161	23	PRKCA,ADCY2,ITPR2
2.173e-03	-6.13	Aldosterone synthesis and secretion	KEGG pathways	hsa04925	82	3	7161	23	ITPR2,PRKCA,ADCY2
2.181e-03	-6.13	MBNL2 (muscleblind like splicing regulator 2)	protein interactions	10150	27	2	19454	50	MSI2,QKI
2.181e-03	-6.13	HPCAL4 (hippocalcin like 4)	protein interactions	51440	27	2	19454	50	GPM6A,AQP4
2.181e-03	-6.13	KCNJ12 (potassium inwardly rectifying channel subfamily J member 12)	protein interactions	3768	27	2	19454	50	DTNA,ABLIM1
2.185e-03	-6.13	LYN (LYN proto-oncogene, Src family tyrosine kinase)	protein interactions	4067	713	7	19454	50	SLC1A3,DTNA,FMN2,ABLIM1,MACF1,MSI2,PARD3
2.200e-03	-6.12	EZR (ezrin)	protein interactions	7430	526	6	19454	50	DTNA,SORBS1,NEBL,PRKCA,ABLIM1,MACF1
2.217e-03	-6.11	YWHAZ (tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein zeta)	protein interactions	7534	1138	9	19454	50	NHSL1,ABLIM1,MACF1,PRKCA,SORBS1,PITPNC1,PARD3B,PARD3,SASH1
2.282e-03	-6.08	transmembrane transporter activity	molecular function	GO:0022857	1110	9	18094	48	RYR3,AQP4,TRPM3,SLC1A3,ATP13A4,ITPR2,SLC4A4,GPM6A,SLC1A2
2.296e-03	-6.08	breast-carcinoma-ductolobular_carcinoma	COSMIC cancer mutations	breast-carcinoma-ductolobular_carcinoma	1619	12	16828	50	PTPRZ1,CDH20,QKI,SORBS1,DTNA,FMN2,PARD3B,MACF1,LIFR,CTNND2,ABLIM1,RORA
2.296e-03	-6.08	ductolobular_carcinoma	COSMIC cancer mutations	ductolobular_carcinoma	1619	12	16828	50	CDH20,PARD3B,PTPRZ1,QKI,ABLIM1,CTNND2,DTNA,LIFR,MACF1,SORBS1,FMN2,RORA
2.304e-03	-6.07	C4-dicarboxylate transport	biological process	GO:0015740	26	2	18204	50	SLC1A2,SLC1A3
2.304e-03	-6.07	regulation of macrophage differentiation	biological process	GO:0045649	26	2	18204	50	QKI,PRKCA
2.319e-03	-6.07	CTNNB1 (catenin beta 1)	protein interactions	1499	926	8	19454	50	PARD3,PARD3B,CTNND2,SORBS1,PRKCA,DTNA,PTPRZ1,NHSL1
2.321e-03	-6.07	GFAP (glial fibrillary acidic protein)	protein interactions	2670	217	4	19454	50	PRKCA,RORA,ABLIM1,NKAIN3
2.333e-03	-6.06	large_intestine-caecum-carcinoma-adenocarcinoma	COSMIC cancer mutations	large_intestine-caecum-carcinoma-adenocarcinoma	14236	49	16828	50	TRPS1,NEBL,NRG3,RFX4,CDH20,QKI,CSGALNACT1,CTNND2,GPC5,NPAS3,SASH1,ATP13A4,DCLK2,PRKCA,PPP2R2B,LSAMP,BMPR1B,LIFR,PITPNC1,RORA,RYR3,PARD3B,SOX5,FBXL7,MGAT4C,GPM6A,GLIS3,ITPR2,ZBTB20,SORBS1,SLC4A4,ADCY2,FMN2,SLC1A3,PARD3,ABLIM1,NTM,MACF1,NHSL1,AQP4,SPARCL1,TRPM3,NFIA,NKAIN3,DTNA,MAML2,PTPRZ1,SLC1A2,NTRK2
2.399e-03	-6.03	calcium ion transmembrane transport	biological process	GO:0070588	205	4	18204	50	RYR3,GPM6A,TRPM3,ITPR2
2.399e-03	-6.03	Calcium signaling pathway	KEGG pathways	hsa04020	181	4	7161	23	ITPR2,PRKCA,ADCY2,RYR3
2.399e-03	-6.03	Calcium signaling pathway	KEGG pathways	ko04020	181	4	7161	23	ADCY2,PRKCA,ITPR2,RYR3
2.421e-03	-6.02	caecum	COSMIC cancer mutations	caecum	14248	49	16828	50	BMPR1B,DCLK2,PRKCA,PPP2R2B,LSAMP,ATP13A4,CTNND2,GPC5,NPAS3,SASH1,RFX4,CDH20,QKI,CSGALNACT1,TRPS1,NEBL,NRG3,SLC1A2,PTPRZ1,NTRK2,DTNA,MAML2,AQP4,SPARCL1,TRPM3,NFIA,NKAIN3,ABLIM1,NTM,MACF1,NHSL1,PARD3,ZBTB20,ITPR2,GLIS3,SORBS1,SLC4A4,FMN2,SLC1A3,ADCY2,RYR3,SOX5,PARD3B,FBXL7,MGAT4C,GPM6A,LIFR,PITPNC1,RORA
2.424e-03	-6.02	HUNK (hormonally up-regulated Neu-associated kinase)	protein interactions	30811	104	3	19454	50	ABLIM1,SPARCL1,SORBS1
2.481e-03	-6.00	prostate-adenoma	COSMIC cancer mutations	prostate-adenoma	1634	12	16828	50	SOX5,PTPRZ1,TRPM3,PARD3,PRKCA,MACF1,ZBTB20,NPAS3,DCLK2,GPC5,SASH1,NEBL
2.514e-03	-5.99	INSC (INSC spindle orientation adaptor protein)	protein interactions	387755	29	2	19454	50	PARD3B,PARD3
2.519e-03	-5.98	Myometrial Relaxation and Contraction Pathways	WikiPathways	WP289	158	4	5310	20	ITPR2,ADCY2,RYR3,PRKCA
2.545e-03	-5.97	skin-scalp-malignant_melanoma	COSMIC cancer mutations	skin-scalp-malignant_melanoma	634	7	16828	50	SORBS1,NTM,PTPRZ1,NFIA,NEBL,FMN2,PPP2R2B
2.570e-03	-5.96	TAS2R20 (taste 2 receptor member 20)	protein interactions	259295	1	1	19454	50	PRKCA
2.570e-03	-5.96	Hipk3 (homeodomain interacting protein kinase 3)	protein interactions	15259	1	1	19454	50	GLIS3
2.570e-03	-5.96	Isl1 (ISL1 transcription factor, LIM/homeodomain)	protein interactions	16392	1	1	19454	50	GLIS3
2.570e-03	-5.96	Lztr1 (leucine-zipper-like transcriptional regulator, 1)	protein interactions	66863	1	1	19454	50	BMPR1B
2.570e-03	-5.96	fbxw7.L (F-box and WD repeat domain containing 7 L homeolog)	protein interactions	734230	1	1	19454	50	PRKCA
2.570e-03	-5.96	Agtrap (angiotensin II, type I receptor-associated protein)	protein interactions	11610	1	1	19454	50	PITPNC1
2.570e-03	-5.96	Dcaf7 (DDB1 and CUL4 associated factor 7)	protein interactions	71833	1	1	19454	50	BMPR1B
2.570e-03	-5.96	1700006A11Rik (RIKEN cDNA 1700006A11 gene)	protein interactions	71824	1	1	19454	50	BMPR1B
2.570e-03	-5.96	Bdnf (brain derived neurotrophic factor)	protein interactions	12064	1	1	19454	50	NTRK2
2.570e-03	-5.96	Dynlt1 (dynein light chain Tctex-type 1)	protein interactions	83462	1	1	19454	50	NTRK2
2.586e-03	-5.96	CaM pathway	REACTOME pathways	R-HSA-111997	28	2	10285	28	ADCY2,PRKCA
2.586e-03	-5.96	Calmodulin induced events	REACTOME pathways	R-HSA-111933	28	2	10285	28	PRKCA,ADCY2
2.614e-03	-5.95	response to alkaloid	biological process	GO:0043279	100	3	18204	50	RYR3,SLC1A3,SLC1A2
2.638e-03	-5.94	haematopoietic_and_lymphoid_tissue-spleen-lymphoid_neoplasm-marginal_zone_lymphoma	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue-spleen-lymphoid_neoplasm-marginal_zone_lymphoma	323	5	16828	50	PARD3B,NTM,PTPRZ1,SORBS1,ADCY2
2.652e-03	-5.93	Transmission across Chemical Synapses	REACTOME pathways	R-HSA-112315	217	4	10285	28	SLC1A3,SLC1A2,ADCY2,PRKCA
2.653e-03	-5.93	brain-derived neurotrophic factor receptor activity	molecular function	GO:0060175	1	1	18094	48	NTRK2
2.653e-03	-5.93	internal N(7)-methylguanine-containing RNA reader activity	molecular function	GO:0160089	1	1	18094	48	QKI
2.653e-03	-5.93	peptidoglycan glycosyltransferase activity	molecular function	GO:0008955	1	1	18094	48	CSGALNACT1
2.659e-03	-5.93	Gap junction	KEGG pathways	hsa04540	88	3	7161	23	ITPR2,PRKCA,ADCY2
2.659e-03	-5.93	Gap junction	KEGG pathways	ko04540	88	3	7161	23	ITPR2,ADCY2,PRKCA
2.670e-03	-5.93	positive regulation of oligodendrocyte differentiation	biological process	GO:0048714	28	2	18204	50	PTPRZ1,QKI
2.670e-03	-5.93	regulation of lipopolysaccharide-mediated signaling pathway	biological process	GO:0031664	28	2	18204	50	PRKCA,SASH1
2.673e-03	-5.92	ligand-gated calcium channel activity	molecular function	GO:0099604	29	2	18094	48	ITPR2,RYR3
2.673e-03	-5.92	amino acid:monoatomic cation symporter activity	molecular function	GO:0005416	29	2	18094	48	SLC1A2,SLC1A3
2.697e-03	-5.92	STAR_dimer	pfam domains	PF16544	1	1	17795	48	QKI
2.697e-03	-5.92	Quaking_NLS	pfam domains	PF16551	1	1	17795	48	QKI
2.697e-03	-5.92	MAML2_TAD	pfam domains	PF20804	1	1	17795	48	MAML2
2.697e-03	-5.92	LIFR_N	pfam domains	PF18207	1	1	17795	48	LIFR
2.700e-03	-5.91	Quaking_NLS	interpro domains	IPR032367	1	1	18521	50	QKI
2.700e-03	-5.91	cPKC_alpha	interpro domains	IPR034663	1	1	18521	50	PRKCA
2.700e-03	-5.91	TRPS1	interpro domains	IPR028440	1	1	18521	50	TRPS1
2.700e-03	-5.91	MAML2_TAD	interpro domains	IPR048452	1	1	18521	50	MAML2
2.700e-03	-5.91	SASH1_SAM_repeat2	interpro domains	IPR037630	1	1	18521	50	SASH1
2.700e-03	-5.91	LIFR_N	interpro domains	IPR040901	1	1	18521	50	LIFR
2.700e-03	-5.91	SPARC-like_p1	interpro domains	IPR016359	1	1	18521	50	SPARCL1
2.700e-03	-5.91	SORBS1_SH3_2	interpro domains	IPR035611	1	1	18521	50	SORBS1
2.700e-03	-5.91	STAR_dimer	interpro domains	IPR032377	1	1	18521	50	QKI
2.700e-03	-5.91	NTRK2	interpro domains	IPR020455	1	1	18521	50	NTRK2
2.700e-03	-5.91	SASH1_SH3	interpro domains	IPR035720	1	1	18521	50	SASH1
2.700e-03	-5.91	SORBS1_SH3	interpro domains	IPR035606	1	1	18521	50	SORBS1
2.700e-03	-5.91	SORBS1_SH3_1	interpro domains	IPR035610	1	1	18521	50	SORBS1
2.700e-03	-5.91	Nebulette_SH3	interpro domains	IPR035631	1	1	18521	50	NEBL
2.700e-03	-5.91	SASH1_SAM_repeat1	interpro domains	IPR037627	1	1	18521	50	SASH1
2.718e-03	-5.91	NR3C1 (nuclear receptor subfamily 3 group C member 1)	protein interactions	2908	950	8	19454	50	ZBTB20,PPP2R2B,CTNND2,ADCY2,TRPS1,ATP13A4,SLC1A3,NFIA
2.747e-03	-5.90	trans-synaptic signaling by neuropeptide	biological process	GO:0099540	1	1	18204	50	NTRK2
2.747e-03	-5.90	trans-synaptic signaling by neuropeptide, modulating synaptic transmission	biological process	GO:0099551	1	1	18204	50	NTRK2
2.747e-03	-5.90	directional guidance of interneurons involved in migration from the subpallium to the cortex	biological process	GO:0021840	1	1	18204	50	NRG3
2.747e-03	-5.90	chemorepulsion involved in interneuron migration from the subpallium to the cortex	biological process	GO:0021842	1	1	18204	50	NRG3
2.747e-03	-5.90	positive regulation of angiotensin-activated signaling pathway	biological process	GO:0110063	1	1	18204	50	PRKCA
2.747e-03	-5.90	homologous chromosome movement towards spindle pole in meiosis I anaphase	biological process	GO:0051758	1	1	18204	50	FMN2
2.750e-03	-5.90	bone-Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour	COSMIC cancer mutations	bone-Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour	6023	28	16828	50	NTRK2,PTPRZ1,MAML2,DTNA,DCLK2,ATP13A4,NKAIN3,SPARCL1,TRPM3,MACF1,CTNND2,NPAS3,ABLIM1,SASH1,CSGALNACT1,PARD3,SLC4A4,ZBTB20,GLIS3,ITPR2,SLC1A3,ADCY2,RYR3,SOX5,LIFR,RORA,NRG3,NEBL
2.760e-03	-5.89	Sudden Infant Death Syndrome (SIDS) Susceptibility Pathways	WikiPathways	WP706	162	4	5310	20	RORA,SLC1A3,NTRK2,AQP4
2.782e-03	-5.88	serous_carcinoma	COSMIC cancer mutations	serous_carcinoma	10987	42	16828	50	ATP13A4,TRPM3,GPC5,CTNND2,NPAS3,NTM,MACF1,NHSL1,SASH1,PTPRZ1,SLC1A2,NTRK2,BMPR1B,DTNA,DCLK2,MAML2,PRKCA,PPP2R2B,LSAMP,RYR3,SOX5,PARD3B,FBXL7,MGAT4C,TRPS1,LIFR,NEBL,RORA,NRG3,CDH20,PARD3,QKI,CSGALNACT1,ZBTB20,GLIS3,ITPR2,SORBS1,SLC4A4,ADCY2,SLC1A3,FMN2,MSI2
2.862e-03	-5.86	ACTB (actin beta)	protein interactions	60	958	8	19454	50	NEBL,SORBS1,NHSL1,DTNA,PRKCA,MACF1,FMN2,ABLIM1
2.863e-03	-5.86	myelination in peripheral nervous system	biological process	GO:0022011	29	2	18204	50	NTRK2,PARD3
2.863e-03	-5.86	peripheral nervous system axon ensheathment	biological process	GO:0032292	29	2	18204	50	PARD3,NTRK2
2.866e-03	-5.85	beta-catenin binding	molecular function	GO:0008013	107	3	18094	48	CTNND2,CDH20,RORA
2.870e-03	-5.85	AVPR1B (arginine vasopressin receptor 1B)	protein interactions	553	31	2	19454	50	FMN2,PRKCA
2.883e-03	-5.85	urinary_tract-bladder-carcinoma-transitional_cell_carcinoma	COSMIC cancer mutations	urinary_tract-bladder-carcinoma-transitional_cell_carcinoma	6040	28	16828	50	SLC1A3,ADCY2,FMN2,SORBS1,SLC4A4,GLIS3,ITPR2,ZBTB20,PARD3,CDH20,RFX4,NRG3,NEBL,TRPS1,GPM6A,MGAT4C,PARD3B,DTNA,NTRK2,PTPRZ1,SASH1,MACF1,ABLIM1,GPC5,NFIA,TRPM3,SPARCL1,ATP13A4
2.899e-03	-5.84	transitional_cell_carcinoma	COSMIC cancer mutations	transitional_cell_carcinoma	6042	28	16828	50	RFX4,CDH20,PARD3,SLC4A4,SORBS1,ZBTB20,GLIS3,ITPR2,FMN2,ADCY2,SLC1A3,PARD3B,GPM6A,MGAT4C,TRPS1,NRG3,NEBL,NTRK2,PTPRZ1,DTNA,ATP13A4,NFIA,SPARCL1,TRPM3,MACF1,GPC5,ABLIM1,SASH1
2.931e-03	-5.83	marginal_zone_lymphoma	COSMIC cancer mutations	marginal_zone_lymphoma	331	5	16828	50	SORBS1,PARD3B,NTM,PTPRZ1,ADCY2
2.966e-03	-5.82	Ca-dependent events	REACTOME pathways	R-HSA-111996	30	2	10285	28	PRKCA,ADCY2
2.968e-03	-5.82	Transport of inorganic cations/anions and amino acids/oligopeptides	REACTOME pathways	R-HSA-425393	107	3	10285	28	SLC1A2,SLC4A4,SLC1A3
2.972e-03	-5.82	-	gene3d domains	1.20.5.4010	1	1	14470	43	QKI
2.991e-03	-5.81	TBR1 (T-box brain transcription factor 1)	protein interactions	10716	112	3	19454	50	NFIA,TRPS1,SOX5
3.002e-03	-5.81	neural precursor cell proliferation	biological process	GO:0061351	105	3	18204	50	RORA,SOX5,NFIA
3.005e-03	-5.81	SH3_domain	interpro domains	IPR001452	222	4	18521	50	SASH1,NEBL,MACF1,SORBS1
3.014e-03	-5.80	tibia	COSMIC cancer mutations	tibia	836	8	16828	50	GPM6A,NKAIN3,QKI,TRPM3,LSAMP,MACF1,ABLIM1,CTNND2
3.017e-03	-5.80	GnRH signaling pathway	KEGG pathways	ko04912	92	3	7161	23	PRKCA,ADCY2,ITPR2
3.017e-03	-5.80	GnRH signaling pathway	KEGG pathways	hsa04912	92	3	7161	23	ADCY2,PRKCA,ITPR2
3.051e-03	-5.79	intracellularly ligand-gated monoatomic ion channel activity	molecular function	GO:0005217	31	2	18094	48	ITPR2,RYR3
3.055e-03	-5.79	CDH1 (cadherin 1)	protein interactions	999	757	7	19454	50	ABLIM1,MACF1,NHSL1,CTNND2,PARD3,SORBS1,NEBL
3.057e-03	-5.79	DSG3 (desmoglein 3)	protein interactions	1830	32	2	19454	50	CSGALNACT1,PPP2R2B
3.062e-03	-5.79	L-glutamate import	biological process	GO:0051938	30	2	18204	50	SLC1A3,SLC1A2
3.062e-03	-5.79	neurotransmitter uptake	biological process	GO:0001504	30	2	18204	50	SLC1A2,SLC1A3
3.165e-03	-5.76	Ion_trans	pfam domains	PF00520	109	3	17795	48	ITPR2,TRPM3,RYR3
3.179e-03	-5.75	Ion_trans_dom	interpro domains	IPR005821	109	3	18521	50	RYR3,TRPM3,ITPR2
3.222e-03	-5.74	SMAD7 (SMAD family member 7)	protein interactions	4092	115	3	19454	50	BMPR1B,SOX5,PARD3
3.293e-03	-5.72	Integration of energy metabolism	REACTOME pathways	R-HSA-163685	111	3	10285	28	ITPR2,PRKCA,ADCY2
3.302e-03	-5.71	SKIL (SKI like proto-oncogene)	protein interactions	6498	116	3	19454	50	SPARCL1,MACF1,SASH1
3.304e-03	-5.71	embryonal	COSMIC cancer mutations	embryonal	2659	16	16828	50	PTPRZ1,FMN2,ADCY2,GLIS3,MAML2,SORBS1,TRPM3,SPARCL1,NFIA,PARD3B,RYR3,AQP4,RORA,NPAS3,CTNND2,MACF1
3.304e-03	-5.71	soft_tissue-striated_muscle-rhabdomyosarcoma-embryonal	COSMIC cancer mutations	soft_tissue-striated_muscle-rhabdomyosarcoma-embryonal	2659	16	16828	50	RORA,MACF1,CTNND2,NPAS3,NFIA,SPARCL1,TRPM3,AQP4,RYR3,PARD3B,ADCY2,FMN2,SORBS1,MAML2,GLIS3,PTPRZ1
3.404e-03	-5.68	Circadian entrainment	KEGG pathways	hsa04713	96	3	7161	23	RYR3,PRKCA,ADCY2
3.404e-03	-5.68	Circadian entrainment	KEGG pathways	ko04713	96	3	7161	23	ADCY2,PRKCA,RYR3
3.404e-03	-5.68	cellular response to endogenous stimulus	biological process	GO:0071495	1135	9	18204	50	ITPR2,NFIA,SORBS1,SLC1A3,SOX5,BMPR1B,NTRK2,SLC1A2,RYR3
3.479e-03	-5.66	centrosome localization	biological process	GO:0051642	32	2	18204	50	PARD3,PARD3B
3.479e-03	-5.66	positive regulation of cartilage development	biological process	GO:0061036	32	2	18204	50	SOX5,BMPR1B
3.479e-03	-5.66	transepithelial transport	biological process	GO:0070633	32	2	18204	50	SLC1A2,SLC1A3
3.479e-03	-5.66	microtubule organizing center localization	biological process	GO:0061842	32	2	18204	50	PARD3B,PARD3
3.479e-03	-5.66	positive regulation of ATP metabolic process	biological process	GO:1903580	32	2	18204	50	SLC4A4,ZBTB20
3.505e-03	-5.65	Inflammatory mediator regulation of TRP channels	KEGG pathways	hsa04750	97	3	7161	23	ITPR2,PRKCA,ADCY2
3.505e-03	-5.65	Inflammatory mediator regulation of TRP channels	KEGG pathways	ko04750	97	3	7161	23	ITPR2,PRKCA,ADCY2
3.532e-03	-5.65	NGF signalling via TRKA from the plasma membrane	REACTOME pathways	R-HSA-187037	387	5	10285	28	ITPR2,PRKCA,NRG3,ADCY2,NTRK2
3.622e-03	-5.62	non_small_cell_carcinoma	COSMIC cancer mutations	non_small_cell_carcinoma	5198	25	16828	50	SLC1A3,ADCY2,MSI2,ITPR2,PARD3,QKI,PITPNC1,RORA,TRPS1,LIFR,FBXL7,SOX5,LSAMP,PPP2R2B,DCLK2,PRKCA,MAML2,BMPR1B,PTPRZ1,NTRK2,ABLIM1,NPAS3,CTNND2,SPARCL1,ATP13A4
3.622e-03	-5.62	lung-carcinoma-non_small_cell_carcinoma	COSMIC cancer mutations	lung-carcinoma-non_small_cell_carcinoma	5198	25	16828	50	PARD3,BMPR1B,QKI,PTPRZ1,NTRK2,ADCY2,MSI2,LSAMP,SLC1A3,PPP2R2B,ITPR2,DCLK2,PRKCA,MAML2,FBXL7,SPARCL1,SOX5,ATP13A4,PITPNC1,RORA,ABLIM1,NPAS3,CTNND2,TRPS1,LIFR
3.649e-03	-5.61	TPRA1 (transmembrane protein adipocyte associated 1)	protein interactions	131601	35	2	19454	50	ITPR2,BMPR1B
3.680e-03	-5.60	synapse	cellular component	GO:0045202	1473	10	19108	49	NRG3,SLC1A3,PTPRZ1,SPARCL1,NTRK2,QKI,GPM6A,SLC1A2,CTNND2,DTNA
3.688e-03	-5.60	solute:monoatomic cation symporter activity	molecular function	GO:0015294	117	3	18094	48	SLC1A2,SLC1A3,SLC4A4
3.741e-03	-5.59	connective tissue development	biological process	GO:0061448	232	4	18204	50	NFIA,CSGALNACT1,BMPR1B,SOX5
3.808e-03	-5.57	DELLA	smart domains	SM01129	1	1	9717	37	MACF1
3.826e-03	-5.57	AQUAPORIN4	prints domains	PR02016	1	1	5227	20	AQP4
3.826e-03	-5.57	NTKRECEPTOR2	prints domains	PR01941	1	1	5227	20	NTRK2
3.878e-03	-5.55	organic acid:sodium symporter activity	molecular function	GO:0005343	35	2	18094	48	SLC1A2,SLC1A3
3.929e-03	-5.54	Retrograde endocannabinoid signaling	KEGG pathways	ko04723	101	3	7161	23	ADCY2,PRKCA,ITPR2
3.929e-03	-5.54	Retrograde endocannabinoid signaling	KEGG pathways	hsa04723	101	3	7161	23	ADCY2,PRKCA,ITPR2
4.052e-03	-5.51	glial cell projection	cellular component	GO:0097386	37	2	19108	49	SLC1A2,AQP4
4.071e-03	-5.50	TRNAU1AP (tRNA selenocysteine 1 associated protein 1)	protein interactions	54952	37	2	19454	50	QKI,ZBTB20
4.071e-03	-5.50	PADI3 (peptidyl arginine deiminase 3)	protein interactions	51702	37	2	19454	50	CSGALNACT1,SPARCL1
4.226e-03	-5.47	pancreas-carcinoma-acinar_carcinoma	COSMIC cancer mutations	pancreas-carcinoma-acinar_carcinoma	1978	13	16828	50	ZBTB20,FMN2,PTPRZ1,QKI,CSGALNACT1,BMPR1B,CTNND2,LIFR,NHSL1,SASH1,PARD3B,SOX5,TRPM3
4.226e-03	-5.47	acinar_carcinoma	COSMIC cancer mutations	acinar_carcinoma	1978	13	16828	50	SOX5,PARD3B,PTPRZ1,TRPM3,CSGALNACT1,BMPR1B,QKI,ZBTB20,CTNND2,LIFR,FMN2,NHSL1,SASH1
4.233e-03	-5.46	SH3 Domains	gene3d domains	2.30.30.40	223	4	14470	43	SASH1,SORBS1,MACF1,NEBL
4.258e-03	-5.46	PAX9 (paired box 9)	protein interactions	5083	127	3	19454	50	QKI,NFIA,TRPS1
4.290e-03	-5.45	Pcbp1 (poly(rC) binding protein 1)	protein interactions	23983	38	2	19454	50	MSI2,QKI
4.373e-03	-5.43	MARK2 (microtubule affinity regulating kinase 2)	protein interactions	2011	259	4	19454	50	PARD3B,PARD3,PPP2R2B,DTNA
4.432e-03	-5.42	chondroitin biosynthesis	BIOCYC pathways	HUMAN_PWY-6566	2	1	902	2	CSGALNACT1
4.448e-03	-5.42	Lima1 (LIM domain and actin binding 1)	protein interactions	65970	129	3	19454	50	ABLIM1,ZBTB20,ITPR2
4.449e-03	-5.42	stomach-carcinoma-diffuse_adenocarcinoma	COSMIC cancer mutations	stomach-carcinoma-diffuse_adenocarcinoma	4383	22	16828	50	CTNND2,TRPS1,ABLIM1,MACF1,LIFR,NHSL1,SASH1,NRG3,RYR3,SOX5,MGAT4C,TRPM3,GPM6A,DTNA,GLIS3,ADCY2,FMN2,SLC1A3,RFX4,PTPRZ1,PARD3,QKI
4.449e-03	-5.42	diffuse_adenocarcinoma	COSMIC cancer mutations	diffuse_adenocarcinoma	4383	22	16828	50	ABLIM1,CTNND2,TRPS1,LIFR,MACF1,NHSL1,NRG3,SASH1,SOX5,RYR3,TRPM3,MGAT4C,GPM6A,GLIS3,DTNA,SLC1A3,FMN2,ADCY2,RFX4,PTPRZ1,PARD3,QKI
4.451e-03	-5.41	monoatomic ion transport	biological process	GO:0006811	964	8	18204	50	SLC1A3,GPM6A,ATP13A4,ITPR2,RYR3,TRPM3,SLC4A4,SLC1A2
4.494e-03	-5.41	DIRAS3 (DIRAS family GTPase 3)	protein interactions	9077	261	4	19454	50	DTNA,MACF1,PARD3,FMN2
4.539e-03	-5.39	skin-arm-malignant_melanoma	COSMIC cancer mutations	skin-arm-malignant_melanoma	1308	10	16828	50	TRPS1,NPAS3,ZBTB20,NTM,SORBS1,SLC4A4,MACF1,PRKCA,PARD3B,TRPM3
4.605e-03	-5.38	positive regulation of neurogenesis	biological process	GO:0050769	246	4	18204	50	MACF1,QKI,PTPRZ1,NTRK2
4.631e-03	-5.38	positive regulation of glucose import	biological process	GO:0046326	37	2	18204	50	SLC1A2,SORBS1
4.631e-03	-5.38	positive regulation of purine nucleotide metabolic process	biological process	GO:1900544	37	2	18204	50	ZBTB20,SLC4A4
4.631e-03	-5.38	positive regulation of nucleotide metabolic process	biological process	GO:0045981	37	2	18204	50	ZBTB20,SLC4A4
4.691e-03	-5.36	monoatomic cation transport	biological process	GO:0006812	766	7	18204	50	TRPM3,RYR3,SLC4A4,GPM6A,SLC1A3,ATP13A4,ITPR2
4.705e-03	-5.36	plasma membrane region	cellular component	GO:0098590	1278	9	19108	49	AQP4,SORBS1,SLC1A3,SLC1A2,MACF1,SLC4A4,PARD3B,GPM6A,PARD3
4.708e-03	-5.36	central_nervous_system-brainstem-glioma-oligoastrocytoma_Grade_III	COSMIC cancer mutations	central_nervous_system-brainstem-glioma-oligoastrocytoma_Grade_III	114	3	16828	50	SLC1A2,RYR3,SOX5
4.744e-03	-5.35	DZIP1 (DAZ interacting zinc finger protein 1)	protein interactions	22873	40	2	19454	50	NTRK2,PARD3
4.862e-03	-5.33	haematopoietic_and_lymphoid_tissue-haematopoietic_neoplasm-acute_myeloid_leukaemia	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue-haematopoietic_neoplasm-acute_myeloid_leukaemia	10418	40	16828	50	NFIA,NKAIN3,SPARCL1,TRPM3,ATP13A4,SASH1,NHSL1,MACF1,CTNND2,GPC5,NPAS3,ABLIM1,NTM,NTRK2,SLC1A2,PTPRZ1,PPP2R2B,LSAMP,MAML2,PRKCA,FBXL7,RYR3,PARD3B,SOX5,RORA,NRG3,NEBL,LIFR,QKI,CSGALNACT1,PARD3,RFX4,CDH20,FMN2,MSI2,SLC1A3,ADCY2,SLC4A4,GLIS3,ITPR2
4.862e-03	-5.33	acute_myeloid_leukaemia	COSMIC cancer mutations	acute_myeloid_leukaemia	10418	40	16828	50	SASH1,NHSL1,MACF1,CTNND2,GPC5,NPAS3,NTM,ABLIM1,NFIA,NKAIN3,SPARCL1,TRPM3,ATP13A4,PPP2R2B,LSAMP,MAML2,PRKCA,NTRK2,PTPRZ1,SLC1A2,RORA,NRG3,NEBL,LIFR,FBXL7,RYR3,PARD3B,SOX5,MSI2,FMN2,ADCY2,SLC1A3,SLC4A4,ITPR2,GLIS3,QKI,CSGALNACT1,PARD3,RFX4,CDH20
4.880e-03	-5.32	amino acid import across plasma membrane	biological process	GO:0089718	38	2	18204	50	SLC1A2,SLC1A3
4.910e-03	-5.32	lung-carcinoma-adenocarcinoma	COSMIC cancer mutations	lung-carcinoma-adenocarcinoma	15133	50	16828	50	BMPR1B,DCLK2,PRKCA,LSAMP,PPP2R2B,ATP13A4,NPAS3,CTNND2,GPC5,SASH1,CDH20,RFX4,CSGALNACT1,QKI,MSI2,TRPS1,NEBL,NRG3,PTPRZ1,SLC1A2,NTRK2,DTNA,MAML2,AQP4,TRPM3,SPARCL1,NKAIN3,NFIA,NTM,ABLIM1,MACF1,NHSL1,PARD3,GLIS3,ITPR2,ZBTB20,SLC4A4,SORBS1,SLC1A3,ADCY2,FMN2,SOX5,PARD3B,RYR3,FBXL7,MGAT4C,GPM6A,LIFR,PITPNC1,RORA
4.934e-03	-5.31	VCL (vinculin)	protein interactions	7414	268	4	19454	50	SORBS1,NEBL,MACF1,PRKCA
4.938e-03	-5.31	clear_cell_renal_cell_carcinoma	COSMIC cancer mutations	clear_cell_renal_cell_carcinoma	13924	48	16828	50	PITPNC1,RORA,LIFR,FBXL7,MGAT4C,GPM6A,RYR3,PARD3B,SOX5,FMN2,SLC1A3,ADCY2,ITPR2,ZBTB20,GLIS3,SORBS1,SLC4A4,PARD3,NHSL1,ABLIM1,MACF1,SPARCL1,TRPM3,NFIA,NKAIN3,AQP4,DTNA,MAML2,SLC1A2,PTPRZ1,NTRK2,NEBL,NRG3,TRPS1,MSI2,QKI,CSGALNACT1,CDH20,SASH1,GPC5,CTNND2,NPAS3,ATP13A4,PPP2R2B,LSAMP,DCLK2,PRKCA,BMPR1B
4.938e-03	-5.31	kidney-carcinoma-clear_cell_renal_cell_carcinoma	COSMIC cancer mutations	kidney-carcinoma-clear_cell_renal_cell_carcinoma	13924	48	16828	50	NHSL1,MACF1,ABLIM1,NKAIN3,NFIA,TRPM3,SPARCL1,AQP4,MAML2,DTNA,NTRK2,SLC1A2,PTPRZ1,RORA,PITPNC1,LIFR,GPM6A,FBXL7,MGAT4C,PARD3B,SOX5,RYR3,SLC1A3,FMN2,ADCY2,SORBS1,SLC4A4,ZBTB20,GLIS3,ITPR2,PARD3,SASH1,NPAS3,CTNND2,GPC5,ATP13A4,LSAMP,PPP2R2B,PRKCA,DCLK2,BMPR1B,NRG3,NEBL,TRPS1,MSI2,CSGALNACT1,QKI,CDH20
4.944e-03	-5.31	calcium ion transport	biological process	GO:0006816	251	4	18204	50	TRPM3,RYR3,GPM6A,ITPR2
4.969e-03	-5.30	intracellular chemical homeostasis	biological process	GO:0055082	581	6	18204	50	SLC4A4,AQP4,ZBTB20,RYR3,SLC1A3,ATP13A4
5.049e-03	-5.29	FOXP1 (forkhead box P1)	protein interactions	27086	135	3	19454	50	NFIA,SOX5,SASH1
5.049e-03	-5.29	Myo1c (myosin IC)	protein interactions	17913	135	3	19454	50	TRPS1,ITPR2,ABLIM1
5.109e-03	-5.28	forebrain development	biological process	GO:0030900	408	5	18204	50	RFX4,SLC1A2,NTRK2,DCLK2,NRG3
5.118e-03	-5.28	cell-cell junction assembly	biological process	GO:0007043	127	3	18204	50	CDH20,PRKCA,PARD3
5.127e-03	-5.27	EF-hand-dom_pair	interpro domains	IPR011992	258	4	18521	50	DTNA,MACF1,RYR3,SPARCL1
5.127e-03	-5.27	RHOB (ras homolog family member B)	protein interactions	388	832	7	19454	50	DTNA,SLC1A3,MACF1,ABLIM1,FMN2,PARD3B,PARD3
5.134e-03	-5.27	Ppp3cc (protein phosphatase 3, catalytic subunit, gamma isoform)	protein interactions	19057	2	1	19454	50	BMPR1B
5.134e-03	-5.27	Kdm4c (lysine (K)-specific demethylase 4C)	protein interactions	76804	2	1	19454	50	GLIS3
5.134e-03	-5.27	Grin2c (glutamate ionotropic receptor NMDA type subunit 2C)	protein interactions	24411	2	1	19454	50	PRKCA
5.134e-03	-5.27	Klhl1 (kelch-like 1)	protein interactions	93688	2	1	19454	50	BMPR1B
5.134e-03	-5.27	Sh3kbp1 (SH3-domain kinase binding protein 1)	protein interactions	58194	2	1	19454	50	BMPR1B
5.134e-03	-5.27	Bcr (BCR activator of RhoGEF and GTPase)	protein interactions	110279	2	1	19454	50	BMPR1B
5.134e-03	-5.27	Bmpr2 (bone morphogenetic protein receptor type 2)	protein interactions	12168	2	1	19454	50	BMPR1B
5.134e-03	-5.27	numb (numb)	protein interactions	34263	2	1	19454	50	PRKCA
5.134e-03	-5.27	Fkbp1a (FK506 binding protein 1a)	protein interactions	14225	2	1	19454	50	BMPR1B
5.134e-03	-5.27	Fbxo34 (F-box protein 34)	protein interactions	78938	2	1	19454	50	BMPR1B
5.134e-03	-5.27	Mknk2 (MAP kinase-interacting serine/threonine kinase 2)	protein interactions	17347	2	1	19454	50	BMPR1B
5.134e-03	-5.27	Fkbp1b (FK506 binding protein 1b)	protein interactions	14226	2	1	19454	50	BMPR1B
5.134e-03	-5.27	Irf7 (interferon regulatory factor 7)	protein interactions	54123	2	1	19454	50	BMPR1B
5.134e-03	-5.27	Zmym2 (zinc finger, MYM-type 2)	protein interactions	76007	2	1	19454	50	GLIS3
5.134e-03	-5.27	arm	COSMIC cancer mutations	arm	1331	10	16828	50	SLC4A4,SORBS1,MACF1,PRKCA,TRPS1,NTM,NPAS3,ZBTB20,TRPM3,PARD3B
5.220e-03	-5.26	GRIA2 (glutamate ionotropic receptor AMPA type subunit 2)	protein interactions	2891	42	2	19454	50	GPM6A,PRKCA
5.231e-03	-5.25	myelination	biological process	GO:0042552	128	3	18204	50	QKI,PARD3,NTRK2
5.252e-03	-5.25	Cholinergic synapse	KEGG pathways	hsa04725	112	3	7161	23	ITPR2,PRKCA,ADCY2
5.299e-03	-5.24	histone H3T6 kinase activity	molecular function	GO:0035403	2	1	18094	48	PRKCA
5.299e-03	-5.24	leukemia inhibitory factor receptor activity	molecular function	GO:0004923	2	1	18094	48	LIFR
5.299e-03	-5.24	calcium,diacylglycerol-dependent serine/threonine kinase activity	molecular function	GO:0004698	2	1	18094	48	PRKCA
5.299e-03	-5.24	protein complex oligomerization	biological process	GO:0051259	256	4	18204	50	SLC1A2,AQP4,RYR3,TRPM3
5.366e-03	-5.23	NFIB (nuclear factor I B)	protein interactions	4781	138	3	19454	50	SOX5,NFIA,TRPS1
5.373e-03	-5.23	positive regulation of multicellular organismal process	biological process	GO:0051240	1691	11	18204	50	NTRK2,RORA,BMPR1B,PRKCA,PTPRZ1,PARD3,SASH1,QKI,MACF1,ZBTB20,SOX5
5.388e-03	-5.22	LIFR_D2	pfam domains	PF17971	2	1	17795	48	LIFR
5.388e-03	-5.22	LIF-R_Ig-like	pfam domains	PF21177	2	1	17795	48	LIFR
5.392e-03	-5.22	Alpha_CARP_receptor-type	interpro domains	IPR041887	2	1	18521	50	PTPRZ1
5.392e-03	-5.22	Formin_Cappuccino_subfam	interpro domains	IPR001265	2	1	18521	50	FMN2
5.392e-03	-5.22	Distrobrevin	interpro domains	IPR017432	2	1	18521	50	DTNA
5.392e-03	-5.22	LIF-R-like_Ig-like	interpro domains	IPR048497	2	1	18521	50	LIFR
5.392e-03	-5.22	MSI_RRM2	interpro domains	IPR034126	2	1	18521	50	MSI2
5.392e-03	-5.22	LIFR_D2	interpro domains	IPR040817	2	1	18521	50	LIFR
5.392e-03	-5.22	Osteonectin_CS	interpro domains	IPR001999	2	1	18521	50	SPARCL1
5.395e-03	-5.22	cyclic purine nucleotide metabolic process	biological process	GO:0052652	40	2	18204	50	RORA,ADCY2
5.409e-03	-5.22	I-set	pfam domains	PF07679	132	3	17795	48	NTRK2,NTM,LSAMP
5.432e-03	-5.22	Ig_I-set	interpro domains	IPR013098	132	3	18521	50	NTRK2,LSAMP,NTM
5.440e-03	-5.21	sarcoplasmic reticulum membrane	cellular component	GO:0033017	43	2	19108	49	RYR3,ITPR2
5.461e-03	-5.21	ensheathment of neurons	biological process	GO:0007272	130	3	18204	50	PARD3,NTRK2,QKI
5.461e-03	-5.21	axon ensheathment	biological process	GO:0008366	130	3	18204	50	QKI,NTRK2,PARD3
5.485e-03	-5.21	skin-head_neck-malignant_melanoma-superficial_spreading	COSMIC cancer mutations	skin-head_neck-malignant_melanoma-superficial_spreading	923	8	16828	50	SORBS1,MACF1,LIFR,CTNND2,PPP2R2B,ADCY2,ATP13A4,MGAT4C
5.486e-03	-5.21	myofibroblast contraction	biological process	GO:1990764	2	1	18204	50	QKI
5.486e-03	-5.21	UDP-glucuronate metabolic process	biological process	GO:0046398	2	1	18204	50	CSGALNACT1
5.486e-03	-5.21	negative regulation of 3'-UTR-mediated mRNA stabilization	biological process	GO:1905869	2	1	18204	50	QKI
5.486e-03	-5.21	positive regulation of dense core granule biogenesis	biological process	GO:2000707	2	1	18204	50	PRKCA
5.486e-03	-5.21	chondroitin sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process	biological process	GO:0050653	2	1	18204	50	CSGALNACT1
5.492e-03	-5.20	cellular component assembly	biological process	GO:0022607	2472	14	18204	50	GPM6A,ABLIM1,FMN2,PRKCA,SLC1A2,NEBL,RYR3,NRG3,CDH20,PARD3,SORBS1,RFX4,AQP4,TRPM3
5.545e-03	-5.19	neutral L-amino acid transmembrane transporter activity	molecular function	GO:0015175	42	2	18094	48	SLC1A3,SLC1A2
5.662e-03	-5.17	cyclic nucleotide metabolic process	biological process	GO:0009187	41	2	18204	50	RORA,ADCY2
5.692e-03	-5.17	actin binding	molecular function	GO:0003779	434	5	18094	48	FMN2,NEBL,SORBS1,ABLIM1,MACF1
5.697e-03	-5.17	amino acid transport	biological process	GO:0006865	132	3	18204	50	SLC1A3,NTRK2,SLC1A2
5.767e-03	-5.16	sarcolemma	cellular component	GO:0042383	142	3	19108	49	AQP4,DTNA,RYR3
5.935e-03	-5.13	active monoatomic ion transmembrane transporter activity	molecular function	GO:0022853	274	4	18094	48	SLC4A4,ATP13A4,SLC1A3,SLC1A2
5.935e-03	-5.13	-	gene3d domains	6.20.350.10	2	1	14470	43	RYR3
5.935e-03	-5.13	Schwann cell development	biological process	GO:0014044	42	2	18204	50	PARD3,NTRK2
6.001e-03	-5.12	biliary_tract-gallbladder-carcinoma-adenocarcinoma	COSMIC cancer mutations	biliary_tract-gallbladder-carcinoma-adenocarcinoma	2821	16	16828	50	TRPS1,CTNND2,MACF1,NHSL1,PITPNC1,SASH1,NRG3,RYR3,SPARCL1,TRPM3,NKAIN3,ITPR2,SLC4A4,FMN2,PTPRZ1,PARD3
6.001e-03	-5.12	gallbladder	COSMIC cancer mutations	gallbladder	2821	16	16828	50	NKAIN3,TRPM3,SPARCL1,RYR3,NRG3,SASH1,PITPNC1,NHSL1,MACF1,CTNND2,TRPS1,PARD3,PTPRZ1,FMN2,SLC4A4,ITPR2
6.024e-03	-5.11	Vasopressin regulates renal water homeostasis via Aquaporins	REACTOME pathways	R-HSA-432040	43	2	10285	28	ADCY2,AQP4
6.037e-03	-5.11	Calml3 (calmodulin-like 3)	protein interactions	70405	144	3	19454	50	ZBTB20,MACF1,ABLIM1
6.087e-03	-5.10	phosphatidylinositol binding	molecular function	GO:0035091	276	4	18094	48	PARD3B,PARD3,ITPR2,PITPNC1
6.126e-03	-5.10	neuron projection	cellular component	GO:0043005	1331	9	19108	49	DTNA,ADCY2,CTNND2,SLC1A2,PARD3,GPM6A,NTRK2,BMPR1B,SLC1A3
6.323e-03	-5.06	central_nervous_system-brain-glioma-oligodendroglioma_Grade_III	COSMIC cancer mutations	central_nervous_system-brain-glioma-oligodendroglioma_Grade_III	249	4	16828	50	MGAT4C,MACF1,PTPRZ1,GLIS3
6.347e-03	-5.06	regulation of multicellular organismal development	biological process	GO:2000026	1484	10	18204	50	PTPRZ1,TRPS1,PRKCA,SOX5,NTRK2,BMPR1B,MACF1,QKI,PARD3,SASH1
6.405e-03	-5.05	SH3	prosite domains	PS50002	222	4	12186	41	MACF1,NEBL,SASH1,SORBS1
6.441e-03	-5.04	regulation of generation of precursor metabolites and energy	biological process	GO:0043467	138	3	18204	50	SLC4A4,ZBTB20,SORBS1
6.498e-03	-5.04	positive regulation of glucose transmembrane transport	biological process	GO:0010828	44	2	18204	50	SORBS1,SLC1A2
6.500e-03	-5.04	CNTN1 (contactin 1)	protein interactions	1272	47	2	19454	50	PTPRZ1,GPM6A
6.512e-03	-5.03	Vascular smooth muscle contraction	KEGG pathways	ko04270	121	3	7161	23	ITPR2,PRKCA,ADCY2
6.512e-03	-5.03	Vascular smooth muscle contraction	KEGG pathways	hsa04270	121	3	7161	23	ITPR2,ADCY2,PRKCA
6.546e-03	-5.03	mixed_intestinal_and_diffuse_adenocarcinoma-unclassifiable	COSMIC cancer mutations	mixed_intestinal_and_diffuse_adenocarcinoma-unclassifiable	951	8	16828	50	PARD3,TRPM3,SLC1A2,ATP13A4,FMN2,MACF1,GPC5,ITPR2
6.546e-03	-5.03	stomach-carcinoma-mixed_intestinal_and_diffuse_adenocarcinoma-unclassifiable	COSMIC cancer mutations	stomach-carcinoma-mixed_intestinal_and_diffuse_adenocarcinoma-unclassifiable	951	8	16828	50	SLC1A2,ATP13A4,PARD3,TRPM3,MACF1,GPC5,ITPR2,FMN2
6.599e-03	-5.02	SOX2 (SRY-box transcription factor 2)	protein interactions	6657	1342	9	19454	50	TRPS1,NFIA,LSAMP,GLIS3,MACF1,ITPR2,MSI2,SOX5,QKI
6.676e-03	-5.01	inorganic cation transmembrane transport	biological process	GO:0098662	618	6	18204	50	ITPR2,SLC4A4,RYR3,GPM6A,SLC1A3,TRPM3
6.709e-03	-5.00	apical junction complex	cellular component	GO:0043296	150	3	19108	49	SORBS1,PARD3B,PARD3
6.718e-03	-5.00	OSTEONECTIN_1	prosite domains	PS00612	2	1	12186	41	SPARCL1
6.718e-03	-5.00	OSTEONECTIN_2	prosite domains	PS00613	2	1	12186	41	SPARCL1
6.748e-03	-5.00	kidney-carcinoma-papillary_renal_cell_carcinoma	COSMIC cancer mutations	kidney-carcinoma-papillary_renal_cell_carcinoma	6364	28	16828	50	MACF1,ABLIM1,NTM,CTNND2,GPC5,SASH1,ATP13A4,NFIA,TRPM3,PRKCA,MAML2,DCLK2,NTRK2,PTPRZ1,BMPR1B,LIFR,NRG3,RORA,PITPNC1,SOX5,RYR3,SLC4A4,ZBTB20,ITPR2,ADCY2,FMN2,RFX4,PARD3
6.748e-03	-5.00	papillary_renal_cell_carcinoma	COSMIC cancer mutations	papillary_renal_cell_carcinoma	6364	28	16828	50	ATP13A4,NFIA,TRPM3,MACF1,GPC5,CTNND2,NTM,ABLIM1,SASH1,NTRK2,PTPRZ1,BMPR1B,MAML2,PRKCA,DCLK2,RYR3,SOX5,LIFR,RORA,NRG3,PITPNC1,RFX4,PARD3,SLC4A4,ZBTB20,ITPR2,ADCY2,FMN2
6.875e-03	-4.98	transmembrane transport	biological process	GO:0055085	1264	9	18204	50	ATP13A4,GPM6A,SLC1A3,ITPR2,TRPM3,RYR3,AQP4,SLC1A2,SLC4A4
6.969e-03	-4.97	monoatomic anion transmembrane transport	biological process	GO:0098656	142	3	18204	50	SLC1A3,SLC1A2,SLC4A4
6.969e-03	-4.97	positive regulation of small molecule metabolic process	biological process	GO:0062013	142	3	18204	50	ZBTB20,SORBS1,SLC4A4
7.064e-03	-4.95	SP7 (Sp7 transcription factor)	protein interactions	121340	297	4	19454	50	QKI,SOX5,NFIA,TRPS1
7.074e-03	-4.95	spleen	COSMIC cancer mutations	spleen	408	5	16828	50	ADCY2,PARD3B,NTM,PTPRZ1,SORBS1
7.084e-03	-4.95	regulation of oligodendrocyte differentiation	biological process	GO:0048713	46	2	18204	50	QKI,PTPRZ1
7.084e-03	-4.95	regulation of myelination	biological process	GO:0031641	46	2	18204	50	PTPRZ1,PARD3
7.084e-03	-4.95	positive regulation of glial cell differentiation	biological process	GO:0045687	46	2	18204	50	QKI,PTPRZ1
7.087e-03	-4.95	symporter activity	molecular function	GO:0015293	148	3	18094	48	SLC1A3,SLC4A4,SLC1A2
7.095e-03	-4.95	enzyme-linked receptor protein signaling pathway	biological process	GO:0007167	626	6	18204	50	LIFR,BMPR1B,NTRK2,NFIA,SORBS1,NRG3
7.135e-03	-4.94	SOX6 (SRY-box transcription factor 6)	protein interactions	55553	153	3	19454	50	NFIA,TRPS1,SOX5
7.154e-03	-4.94	skin-leg-malignant_melanoma-nodular	COSMIC cancer mutations	skin-leg-malignant_melanoma-nodular	258	4	16828	50	PTPRZ1,ATP13A4,SLC4A4,FMN2
7.191e-03	-4.93	cell morphogenesis involved in neuron differentiation	biological process	GO:0048667	443	5	18204	50	PTPRZ1,SLC1A3,CTNND2,PARD3,BMPR1B
7.263e-03	-4.93	cellular response to oxygen-containing compound	biological process	GO:1901701	1047	8	18204	50	ADCY2,SLC1A2,RORA,RYR3,ITPR2,ZBTB20,SLC1A3,SORBS1
7.306e-03	-4.92	leg	COSMIC cancer mutations	leg	969	8	16828	50	PTPRZ1,ATP13A4,SLC4A4,NTM,ZBTB20,NRG3,FMN2,NEBL
7.312e-03	-4.92	metal ion transport	biological process	GO:0030001	630	6	18204	50	ITPR2,SLC4A4,SLC1A3,RYR3,GPM6A,TRPM3
7.353e-03	-4.91	NS-malignant_melanoma	COSMIC cancer mutations	NS-malignant_melanoma	3420	18	16828	50	PRKCA,ITPR2,GLIS3,ADCY2,FMN2,RFX4,PTPRZ1,PARD3,LIFR,MACF1,GPC5,CTNND2,NRG3,PITPNC1,NEBL,ATP13A4,TRPM3,MGAT4C
7.386e-03	-4.91	Schwann cell differentiation	biological process	GO:0014037	47	2	18204	50	NTRK2,PARD3
7.394e-03	-4.91	PPP2R2D (protein phosphatase 2 regulatory subunit Bdelta)	protein interactions	55844	155	3	19454	50	GPC5,PPP2R2B,CSGALNACT1
7.462e-03	-4.90	G alpha (z) signalling events	REACTOME pathways	R-HSA-418597	48	2	10285	28	PRKCA,ADCY2
7.525e-03	-4.89	CEP19 (centrosomal protein 19)	protein interactions	84984	156	3	19454	50	PARD3,ABLIM1,FMN2
7.589e-03	-4.88	skin-extremity-malignant_melanoma	COSMIC cancer mutations	skin-extremity-malignant_melanoma	1875	12	16828	50	FBXL7,RYR3,ATP13A4,PITPNC1,NEBL,SASH1,PARD3,PTPRZ1,CDH20,NTRK2,FMN2,ADCY2
7.617e-03	-4.88	FAM171B (family with sequence similarity 171 member B)	protein interactions	165215	51	2	19454	50	PARD3,NTRK2
7.617e-03	-4.88	Ndc80 (NDC80 kinetochore complex component)	protein interactions	67052	51	2	19454	50	MACF1,NHSL1
7.620e-03	-4.88	extremity	COSMIC cancer mutations	extremity	1876	12	16828	50	ADCY2,FMN2,NTRK2,PTPRZ1,CDH20,PARD3,SASH1,PITPNC1,NEBL,RYR3,ATP13A4,FBXL7
7.631e-03	-4.88	human chr8q23.3	chromosome location	human chr8q23.3	4	1	26134	50	TRPS1
7.639e-03	-4.87	FORMIN	prints domains	PR00828	2	1	5227	20	FMN2
7.674e-03	-4.87	alphav-beta3 integrin-PKCalpha complex	cellular component	GO:0035866	3	1	19108	49	PRKCA
7.691e-03	-4.87	Usp45 (ubiquitin specific petidase 45)	protein interactions	77593	3	1	19454	50	BMPR1B
7.691e-03	-4.87	Smad6 (SMAD family member 6)	protein interactions	17130	3	1	19454	50	BMPR1B
7.691e-03	-4.87	Chn1 (chimerin 1)	protein interactions	108699	3	1	19454	50	BMPR1B
7.691e-03	-4.87	Stk35 (serine/threonine kinase 35)	protein interactions	67333	3	1	19454	50	BMPR1B
7.691e-03	-4.87	Atg16l1 (autophagy related 16 like 1)	protein interactions	77040	3	1	19454	50	BMPR1B
7.691e-03	-4.87	Grm5 (glutamate metabotropic receptor 5)	protein interactions	24418	3	1	19454	50	PRKCA
7.691e-03	-4.87	Plekhb1 (pleckstrin homology domain containing, family B (evectins) member 1)	protein interactions	27276	3	1	19454	50	BMPR1B
7.691e-03	-4.87	Rap2a (RAS related protein 2a)	protein interactions	76108	3	1	19454	50	BMPR1B
7.691e-03	-4.87	QRFPR (pyroglutamylated RFamide peptide receptor)	protein interactions	84109	3	1	19454	50	NTM
7.691e-03	-4.87	IL34 (interleukin 34)	protein interactions	146433	3	1	19454	50	PTPRZ1
7.691e-03	-4.87	Fbxw5 (F-box and WD-40 domain protein 5)	protein interactions	30839	3	1	19454	50	BMPR1B
7.691e-03	-4.87	Spop (speckle-type BTB/POZ protein)	protein interactions	20747	3	1	19454	50	GLIS3
7.691e-03	-4.87	BCO1 (beta-carotene oxygenase 1)	protein interactions	53630	3	1	19454	50	ABLIM1
7.757e-03	-4.86	bronchioloalveolar_adenocarcinoma	COSMIC cancer mutations	bronchioloalveolar_adenocarcinoma	778	7	16828	50	ADCY2,PRKCA,CTNND2,DCLK2,BMPR1B,NTRK2,SOX5
7.757e-03	-4.86	lung-carcinoma-bronchioloalveolar_adenocarcinoma	COSMIC cancer mutations	lung-carcinoma-bronchioloalveolar_adenocarcinoma	778	7	16828	50	ADCY2,CTNND2,DCLK2,PRKCA,BMPR1B,SOX5,NTRK2
7.895e-03	-4.84	haematopoietic_and_lymphoid_tissue-small_intestine-lymphoid_neoplasm-enteropathy_type_T_cell_lymphoma	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue-small_intestine-lymphoid_neoplasm-enteropathy_type_T_cell_lymphoma	45	2	16828	50	MGAT4C,MACF1
7.895e-03	-4.84	enteropathy_type_T_cell_lymphoma	COSMIC cancer mutations	enteropathy_type_T_cell_lymphoma	45	2	16828	50	MGAT4C,MACF1
7.909e-03	-4.84	SH2B2 (SH2B adaptor protein 2)	protein interactions	10603	52	2	19454	50	SORBS1,NTRK2
7.938e-03	-4.84	glucuronylgalactosylproteoglycan 4-beta-N-acetylgalactosaminyltransferase activity	molecular function	GO:0047237	3	1	18094	48	CSGALNACT1
7.938e-03	-4.84	inositol 1,4,5-trisphosphate-gated calcium channel activity	molecular function	GO:0005220	3	1	18094	48	ITPR2
7.938e-03	-4.84	oncostatin-M receptor activity	molecular function	GO:0004924	3	1	18094	48	LIFR
7.938e-03	-4.84	alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity	molecular function	GO:0008454	3	1	18094	48	MGAT4C
7.938e-03	-4.84	cysteine transmembrane transporter activity	molecular function	GO:0033229	3	1	18094	48	SLC1A2
7.939e-03	-4.84	Dopaminergic synapse	KEGG pathways	hsa04728	130	3	7161	23	ITPR2,PRKCA,PPP2R2B
7.939e-03	-4.84	Dopaminergic synapse	KEGG pathways	ko04728	130	3	7161	23	PRKCA,PPP2R2B,ITPR2
8.065e-03	-4.82	SOX5 (SRY-box transcription factor 5)	protein interactions	6660	160	3	19454	50	NFIA,TRPS1,SOX5
8.071e-03	-4.82	LRRCT_2	pfam domains	PF16920	3	1	17795	48	NTRK2
8.071e-03	-4.82	RR_TM4-6	pfam domains	PF06459	3	1	17795	48	RYR3
8.071e-03	-4.82	RyR	pfam domains	PF02026	3	1	17795	48	RYR3
8.071e-03	-4.82	Myelin_PLP	pfam domains	PF01275	3	1	17795	48	GPM6A
8.071e-03	-4.82	SLY	pfam domains	PF12485	3	1	17795	48	SASH1
8.071e-03	-4.82	Sorb	pfam domains	PF02208	3	1	17795	48	SORBS1
8.071e-03	-4.82	SR_plectin_7	pfam domains	PF21097	3	1	17795	48	MACF1
8.071e-03	-4.82	MamL-1	pfam domains	PF09596	3	1	17795	48	MAML2
8.071e-03	-4.82	RYDR_Jsol	pfam domains	PF21119	3	1	17795	48	RYR3
8.078e-03	-4.82	NR_DBD_ROR	interpro domains	IPR044101	3	1	18521	50	RORA
8.078e-03	-4.82	RYDR_Jsol	interpro domains	IPR048581	3	1	18521	50	RYR3
8.078e-03	-4.82	Ryanrecept_TM4-6	interpro domains	IPR009460	3	1	18521	50	RYR3
8.078e-03	-4.82	Ryanodine_rcpt	interpro domains	IPR003032	3	1	18521	50	RYR3
8.078e-03	-4.82	MAML_N_sf	interpro domains	IPR046370	3	1	18521	50	MAML2
8.078e-03	-4.82	Myelin_PLP_CS	interpro domains	IPR018237	3	1	18521	50	GPM6A
8.078e-03	-4.82	NTRK_LRRCT	interpro domains	IPR031635	3	1	18521	50	NTRK2
8.078e-03	-4.82	SoHo_dom	interpro domains	IPR003127	3	1	18521	50	SORBS1
8.078e-03	-4.82	Myelin_PLP	interpro domains	IPR001614	3	1	18521	50	GPM6A
8.078e-03	-4.82	Ryan_recept	interpro domains	IPR013333	3	1	18521	50	RYR3
8.078e-03	-4.82	NTRK	interpro domains	IPR020777	3	1	18521	50	NTRK2
8.078e-03	-4.82	SPRY2_RyR	interpro domains	IPR035764	3	1	18521	50	RYR3
8.078e-03	-4.82	Neuregulin	interpro domains	IPR040180	3	1	18521	50	NRG3
8.078e-03	-4.82	SPRY1_RyR	interpro domains	IPR035761	3	1	18521	50	RYR3
8.078e-03	-4.82	MAML1-3	interpro domains	IPR046369	3	1	18521	50	MAML2
8.078e-03	-4.82	SPIDER	interpro domains	IPR021090	3	1	18521	50	SASH1
8.078e-03	-4.82	ROR_rcpt	interpro domains	IPR003079	3	1	18521	50	RORA
8.078e-03	-4.82	Mastermind-like_N	interpro domains	IPR019082	3	1	18521	50	MAML2
8.078e-03	-4.82	Protein_kinase_C_a/b/g	interpro domains	IPR014375	3	1	18521	50	PRKCA
8.078e-03	-4.82	SPRY3_RyR	interpro domains	IPR035762	3	1	18521	50	RYR3
8.078e-03	-4.82	InsP3_rcpt	interpro domains	IPR000493	3	1	18521	50	ITPR2
8.085e-03	-4.82	signaling	biological process	GO:0023052	4968	22	18204	50	PARD3,NFIA,MAML2,SORBS1,MACF1,SLC1A3,PITPNC1,DCLK2,LIFR,SPARCL1,ITPR2,FMN2,ADCY2,PRKCA,BMPR1B,NTRK2,SLC1A2,RORA,CTNND2,RYR3,DTNA,NRG3
8.097e-03	-4.82	regulation of nervous system development	biological process	GO:0051960	456	5	18204	50	QKI,MACF1,PTPRZ1,NTRK2,PARD3
8.100e-03	-4.82	AFDN (afadin, adherens junction formation factor)	protein interactions	4301	309	4	19454	50	MACF1,PARD3,SORBS1,DTNA
8.218e-03	-4.80	cardiac muscle thin filament assembly	biological process	GO:0071691	3	1	18204	50	NEBL
8.218e-03	-4.80	formin-nucleated actin cable assembly	biological process	GO:0070649	3	1	18204	50	FMN2
8.218e-03	-4.80	formin-nucleated actin cable organization	biological process	GO:0110009	3	1	18204	50	FMN2
8.218e-03	-4.80	cysteine transport	biological process	GO:0042883	3	1	18204	50	SLC1A2
8.218e-03	-4.80	trans-synaptic signaling by BDNF, modulating synaptic transmission	biological process	GO:0099183	3	1	18204	50	NTRK2
8.218e-03	-4.80	UDP-N-acetylgalactosamine metabolic process	biological process	GO:0019276	3	1	18204	50	CSGALNACT1
8.218e-03	-4.80	mammary placode formation	biological process	GO:0060596	3	1	18204	50	NRG3
8.218e-03	-4.80	regulation of dense core granule biogenesis	biological process	GO:2000705	3	1	18204	50	PRKCA
8.218e-03	-4.80	meiotic chromosome movement towards spindle pole	biological process	GO:0016344	3	1	18204	50	FMN2
8.218e-03	-4.80	cysteine transmembrane transport	biological process	GO:1903712	3	1	18204	50	SLC1A2
8.243e-03	-4.80	positive regulation of cell development	biological process	GO:0010720	458	5	18204	50	QKI,MACF1,PTPRZ1,PRKCA,NTRK2
8.387e-03	-4.78	cell cortex	cellular component	GO:0005938	313	4	19108	49	PARD3,PARD3B,FMN2,ITPR2
8.392e-03	-4.78	Chondroitin sulfate/dermatan sulfate metabolism	REACTOME pathways	R-HSA-1793185	51	2	10285	28	GPC5,CSGALNACT1
8.392e-03	-4.78	Neurotransmitter Release Cycle	REACTOME pathways	R-HSA-112310	51	2	10285	28	SLC1A2,SLC1A3
8.392e-03	-4.78	Signaling by ERBB2	REACTOME pathways	R-HSA-1227986	51	2	10285	28	PRKCA,NRG3
8.456e-03	-4.77	kidney-other-neoplasm	COSMIC cancer mutations	kidney-other-neoplasm	10653	40	16828	50	NTRK2,SLC1A2,PTPRZ1,PPP2R2B,LSAMP,MAML2,PRKCA,DTNA,NKAIN3,SPARCL1,TRPM3,AQP4,ATP13A4,SASH1,NHSL1,MACF1,GPC5,CTNND2,ABLIM1,NPAS3,QKI,CSGALNACT1,PARD3,RFX4,CDH20,FMN2,SLC1A3,ADCY2,SORBS1,ITPR2,ZBTB20,GPM6A,FBXL7,MGAT4C,RYR3,SOX5,RORA,NRG3,NEBL,TRPS1
8.476e-03	-4.77	sodium ion transmembrane transporter activity	molecular function	GO:0015081	158	3	18094	48	SLC1A2,SLC4A4,SLC1A3
8.478e-03	-4.77	EF-hand	gene3d domains	1.10.238.10	272	4	14470	43	SPARCL1,RYR3,DTNA,MACF1
8.507e-03	-4.77	TAFA4 (TAFA chemokine like family member 4)	protein interactions	151647	54	2	19454	50	ITPR2,LIFR
8.507e-03	-4.77	SYNM (synemin)	protein interactions	23336	54	2	19454	50	PPP2R2B,DTNA
8.508e-03	-4.77	cellular component organization	biological process	GO:0016043	5636	24	18204	50	DCLK2,NFIA,MACF1,PARD3,CDH20,PARD3B,FMN2,ABLIM1,PTPRZ1,CTNND2,RYR3,NEBL,SLC1A2,PITPNC1,SORBS1,SPARCL1,TRPM3,AQP4,RFX4,GPM6A,NRG3,BMPR1B,CSGALNACT1,PRKCA
8.522e-03	-4.77	Signalling by NGF	REACTOME pathways	R-HSA-166520	477	5	10285	28	ADCY2,NTRK2,PRKCA,NRG3,ITPR2
8.713e-03	-4.74	Aquaporin-mediated transport	REACTOME pathways	R-HSA-445717	52	2	10285	28	AQP4,ADCY2
8.746e-03	-4.74	Activation of PKC Through G Protein-Coupled Receptor	SMPDB pathways	SMP0000749	4	1	1369	3	PRKCA
8.748e-03	-4.74	ZYX (zyxin)	protein interactions	7791	316	4	19454	50	NEBL,SORBS1,MACF1,ABLIM1
8.761e-03	-4.74	biliary_tract	COSMIC cancer mutations	biliary_tract	15309	50	16828	50	ABLIM1,NTM,MACF1,NHSL1,AQP4,TRPM3,SPARCL1,NKAIN3,NFIA,DTNA,MAML2,SLC1A2,PTPRZ1,NTRK2,LIFR,PITPNC1,RORA,SOX5,PARD3B,RYR3,FBXL7,MGAT4C,GPM6A,GLIS3,ZBTB20,ITPR2,SLC4A4,SORBS1,SLC1A3,ADCY2,FMN2,PARD3,NPAS3,CTNND2,GPC5,SASH1,ATP13A4,DCLK2,PRKCA,LSAMP,PPP2R2B,BMPR1B,TRPS1,NEBL,NRG3,MSI2,CDH20,RFX4,CSGALNACT1,QKI
8.771e-03	-4.74	EGR2 (early growth response 2)	protein interactions	1959	165	3	19454	50	NFIA,TRPS1,SOX5
8.771e-03	-4.74	positive regulation of nervous system development	biological process	GO:0051962	296	4	18204	50	NTRK2,PTPRZ1,QKI,MACF1
8.814e-03	-4.73	PLCB1 (phospholipase C beta 1)	protein interactions	23236	55	2	19454	50	PARD3,PRKCA
8.859e-03	-4.73	ovary-other-neoplasm	COSMIC cancer mutations	ovary-other-neoplasm	12717	45	16828	50	TRPS1,NEBL,NRG3,RFX4,CDH20,QKI,CSGALNACT1,MSI2,ATP13A4,GPC5,CTNND2,SASH1,BMPR1B,DCLK2,PRKCA,PPP2R2B,LSAMP,RYR3,PARD3B,SOX5,MGAT4C,FBXL7,GPM6A,LIFR,RORA,PARD3,ZBTB20,GLIS3,ITPR2,SLC4A4,SORBS1,FMN2,SLC1A3,ADCY2,AQP4,SPARCL1,TRPM3,NKAIN3,ABLIM1,NTM,MACF1,NHSL1,SLC1A2,NTRK2,MAML2
8.889e-03	-4.72	-	gene3d domains	1.10.490.160	3	1	14470	43	RYR3
8.889e-03	-4.72	-	gene3d domains	6.10.250.970	3	1	14470	43	MAML2
8.927e-03	-4.72	endometrium-carcinoma-serous_carcinoma	COSMIC cancer mutations	endometrium-carcinoma-serous_carcinoma	1442	10	16828	50	PARD3,TRPM3,RYR3,FMN2,LSAMP,TRPS1,GPC5,CTNND2,SLC4A4,SORBS1
8.945e-03	-4.72	central_nervous_system-temporoparietal-glioma-astrocytoma_Grade_IV	COSMIC cancer mutations	central_nervous_system-temporoparietal-glioma-astrocytoma_Grade_IV	48	2	16828	50	RYR3,PARD3
8.978e-03	-4.71	cell communication	biological process	GO:0007154	5010	22	18204	50	PITPNC1,DCLK2,SLC1A3,MACF1,SORBS1,MAML2,NFIA,PARD3,SPARCL1,LIFR,FMN2,ITPR2,NRG3,RYR3,DTNA,CTNND2,RORA,NTRK2,SLC1A2,BMPR1B,PRKCA,ADCY2
8.982e-03	-4.71	regulation of glycolytic process	biological process	GO:0006110	52	2	18204	50	ZBTB20,SLC4A4
8.982e-03	-4.71	regulation of purine nucleotide catabolic process	biological process	GO:0033121	52	2	18204	50	ZBTB20,SLC4A4
8.982e-03	-4.71	regulation of nucleotide catabolic process	biological process	GO:0030811	52	2	18204	50	ZBTB20,SLC4A4
9.212e-03	-4.69	POU2F1 (POU class 2 homeobox 1)	protein interactions	5451	168	3	19454	50	GPC5,LIFR,SOX5
9.212e-03	-4.69	PPL (periplakin)	protein interactions	5493	168	3	19454	50	NKAIN3,PPP2R2B,ITPR2
9.231e-03	-4.69	ACTA1 (actin alpha 1, skeletal muscle)	protein interactions	58	321	4	19454	50	SORBS1,DTNA,MACF1,PRKCA
9.318e-03	-4.68	neutral amino acid transport	biological process	GO:0015804	53	2	18204	50	SLC1A2,SLC1A3
9.352e-03	-4.67	Apelin signaling pathway	KEGG pathways	hsa04371	138	3	7161	23	ITPR2,ADCY2,RYR3
9.442e-03	-4.66	TREX2 (three prime repair exonuclease 2)	protein interactions	11219	57	2	19454	50	PPP2R2B,PARD3B
9.471e-03	-4.66	Spinal Cord Injury	WikiPathways	WP2431	119	3	5310	20	PRKCA,AQP4,PTPRZ1
9.492e-03	-4.66	monoatomic anion transport	biological process	GO:0006820	159	3	18204	50	SLC1A3,SLC4A4,SLC1A2
9.564e-03	-4.65	side of membrane	cellular component	GO:0098552	715	6	19108	49	LIFR,NTM,GPC5,AQP4,LSAMP,DTNA
9.763e-03	-4.63	SNAP25 (synaptosome associated protein 25)	protein interactions	6616	58	2	19454	50	GPM6A,PRKCA
9.871e-03	-4.62	cell-cell junction	cellular component	GO:0005911	513	5	19108	49	SORBS1,PARD3B,PARD3,CDH20,CTNND2
1.001e-02	-4.60	response to cocaine	biological process	GO:0042220	55	2	18204	50	SLC1A2,SLC1A3
1.001e-02	-4.60	establishment or maintenance of epithelial cell apical/basal polarity	biological process	GO:0045197	55	2	18204	50	PARD3B,PARD3
1.002e-02	-4.60	primitive_neuroectodermal_tumour-medulloblastoma	COSMIC cancer mutations	primitive_neuroectodermal_tumour-medulloblastoma	15350	50	16828	50	MSI2,QKI,CSGALNACT1,RFX4,CDH20,NEBL,NRG3,TRPS1,PPP2R2B,LSAMP,DCLK2,PRKCA,BMPR1B,SASH1,GPC5,CTNND2,NPAS3,ATP13A4,ADCY2,FMN2,SLC1A3,ITPR2,GLIS3,ZBTB20,SORBS1,SLC4A4,PARD3,PITPNC1,RORA,LIFR,FBXL7,MGAT4C,GPM6A,RYR3,SOX5,PARD3B,DTNA,MAML2,SLC1A2,PTPRZ1,NTRK2,NHSL1,ABLIM1,NTM,MACF1,SPARCL1,TRPM3,NFIA,NKAIN3,AQP4
1.002e-02	-4.60	Znf_NHR/GATA	interpro domains	IPR013088	56	2	18521	50	TRPS1,RORA
1.005e-02	-4.60	Ion homeostasis	REACTOME pathways	R-HSA-5578775	56	2	10285	28	RYR3,ITPR2
1.006e-02	-4.60	MYELIN_PLP_1	prosite domains	PS00575	3	1	12186	41	GPM6A
1.006e-02	-4.60	SOHO	prosite domains	PS50831	3	1	12186	41	SORBS1
1.006e-02	-4.60	MYELIN_PLP_2	prosite domains	PS01004	3	1	12186	41	GPM6A
1.009e-02	-4.60	HTATIP2 (HIV-1 Tat interactive protein 2)	protein interactions	10553	59	2	19454	50	PRKCA,PITPNC1
1.013e-02	-4.59	DUSP14 (dual specificity phosphatase 14)	protein interactions	11072	174	3	19454	50	CSGALNACT1,SPARCL1,QKI
1.022e-02	-4.58	internode region of axon	cellular component	GO:0033269	4	1	19108	49	PARD3
1.024e-02	-4.58	CCDC126 (coiled-coil domain containing 126)	protein interactions	90693	4	1	19454	50	GPM6A
1.024e-02	-4.58	Dnaja1 (DnaJ heat shock protein family (Hsp40) member A1)	protein interactions	15502	4	1	19454	50	GLIS3
1.024e-02	-4.58	AVPR1A (arginine vasopressin receptor 1A)	protein interactions	552	4	1	19454	50	PRKCA
1.024e-02	-4.58	Srgap1 (SLIT-ROBO Rho GTPase activating protein 1)	protein interactions	117600	4	1	19454	50	BMPR1B
1.024e-02	-4.58	Nme2 (NME/NM23 nucleoside diphosphate kinase 2)	protein interactions	18103	4	1	19454	50	RORA
1.024e-02	-4.58	Pick1 (protein interacting with PRKCA 1)	protein interactions	84591	4	1	19454	50	PRKCA
1.024e-02	-4.58	Rhebl1 (Ras homolog enriched in brain like 1)	protein interactions	69159	4	1	19454	50	BMPR1B
1.024e-02	-4.58	Cdk14 (cyclin dependent kinase 14)	protein interactions	18647	4	1	19454	50	BMPR1B
1.024e-02	-4.58	Ilkap (integrin-linked kinase-associated serine/threonine phosphatase 2C)	protein interactions	67444	4	1	19454	50	BMPR1B
1.024e-02	-4.58	Naa20 (N(alpha)-acetyltransferase 20, NatB catalytic subunit)	protein interactions	67877	4	1	19454	50	BMPR1B
1.024e-02	-4.58	Ctbp2 (C-terminal binding protein 2)	protein interactions	13017	4	1	19454	50	TRPS1
1.024e-02	-4.58	IER5L (immediate early response 5 like)	protein interactions	389792	4	1	19454	50	PPP2R2B
1.024e-02	-4.58	Nkiras1 (NFKB inhibitor interacting Ras-like protein 1)	protein interactions	69721	4	1	19454	50	BMPR1B
1.024e-02	-4.58	Arhgef6 (Rac/Cdc42 guanine nucleotide exchange factor 6)	protein interactions	73341	4	1	19454	50	BMPR1B
1.029e-02	-4.58	LHX3 (LIM homeobox 3)	protein interactions	8022	175	3	19454	50	SOX5,NFIA,TRPS1
1.034e-02	-4.57	positive regulation of cellular process	biological process	GO:0048522	5719	24	18204	50	FMN2,SLC1A2,RORA,NTRK2,PTPRZ1,NPAS3,PARD3,SASH1,GLIS3,MACF1,NFIA,ZBTB20,LIFR,GPM6A,BMPR1B,PRKCA,GPC5,SORBS1,MAML2,SLC1A3,QKI,RFX4,SLC4A4,SOX5
1.034e-02	-4.57	channel activity	molecular function	GO:0015267	502	5	18094	48	ITPR2,RYR3,AQP4,GPM6A,TRPM3
1.036e-02	-4.57	release of sequestered calcium ion into cytosol	biological process	GO:0051209	56	2	18204	50	RYR3,ITPR2
1.038e-02	-4.57	head_neck	COSMIC cancer mutations	head_neck	15361	50	16828	50	ADCY2,SLC1A3,FMN2,GLIS3,ITPR2,ZBTB20,SORBS1,SLC4A4,PARD3,PITPNC1,RORA,LIFR,FBXL7,MGAT4C,GPM6A,PARD3B,SOX5,RYR3,DTNA,MAML2,SLC1A2,PTPRZ1,NTRK2,NHSL1,NTM,ABLIM1,MACF1,TRPM3,SPARCL1,NKAIN3,NFIA,AQP4,MSI2,CSGALNACT1,QKI,CDH20,RFX4,NEBL,NRG3,TRPS1,LSAMP,PPP2R2B,DCLK2,PRKCA,BMPR1B,SASH1,NPAS3,CTNND2,GPC5,ATP13A4
1.042e-02	-4.56	F11R (F11 receptor)	protein interactions	50848	60	2	19454	50	PRKCA,PARD3
1.042e-02	-4.56	passive transmembrane transporter activity	molecular function	GO:0022803	503	5	18094	48	ITPR2,RYR3,AQP4,GPM6A,TRPM3
1.043e-02	-4.56	actin cytoskeleton	cellular component	GO:0015629	520	5	19108	49	ABLIM1,SORBS1,NEBL,FMN2,MACF1
1.049e-02	-4.56	neuron projection morphogenesis	biological process	GO:0048812	486	5	18204	50	PTPRZ1,CTNND2,GPM6A,BMPR1B,PARD3
1.050e-02	-4.56	Adrenergic signaling in cardiomyocytes	KEGG pathways	hsa04261	144	3	7161	23	PRKCA,ADCY2,PPP2R2B
1.050e-02	-4.56	Adrenergic signaling in cardiomyocytes	KEGG pathways	ko04261	144	3	7161	23	ADCY2,PRKCA,PPP2R2B
1.057e-02	-4.55	brain-derived neurotrophic factor binding	molecular function	GO:0048403	4	1	18094	48	NTRK2
1.057e-02	-4.55	ciliary neurotrophic factor receptor activity	molecular function	GO:0004897	4	1	18094	48	LIFR
1.057e-02	-4.55	ryanodine-sensitive calcium-release channel activity	molecular function	GO:0005219	4	1	18094	48	RYR3
1.061e-02	-4.55	GATA3 (GATA binding protein 3)	protein interactions	2625	177	3	19454	50	NFIA,TRPS1,QKI
1.072e-02	-4.54	negative regulation of sequestering of calcium ion	biological process	GO:0051283	57	2	18204	50	RYR3,ITPR2
1.075e-02	-4.53	Spectrin_2	pfam domains	PF18373	4	1	17795	48	MACF1
1.075e-02	-4.53	P5-ATPase	pfam domains	PF12409	4	1	17795	48	ATP13A4
1.075e-02	-4.53	Glyco_transf_54	pfam domains	PF04666	4	1	17795	48	MGAT4C
1.075e-02	-4.53	Nebulin	pfam domains	PF00880	4	1	17795	48	NEBL
1.075e-02	-4.53	NKAIN	pfam domains	PF05640	4	1	17795	48	NKAIN3
1.075e-02	-4.53	AbLIM_anchor	pfam domains	PF16182	4	1	17795	48	ABLIM1
1.075e-02	-4.53	Spectrin_3	pfam domains	PF21019	4	1	17795	48	MACF1
1.075e-02	-4.53	NfI_DNAbd_pre-N	pfam domains	PF10524	4	1	17795	48	NFIA
1.075e-02	-4.53	NHS	pfam domains	PF15273	4	1	17795	48	NHSL1
1.075e-02	-4.53	TRPM_tetra	pfam domains	PF16519	4	1	17795	48	TRPM3
1.075e-02	-4.53	CTF_NFI	pfam domains	PF00859	4	1	17795	48	NFIA
1.075e-02	-4.53	Spectrin_4	pfam domains	PF21020	4	1	17795	48	MACF1
1.076e-02	-4.53	CTF/NFI_DNA-bd-dom	interpro domains	IPR020604	4	1	18521	50	NFIA
1.076e-02	-4.53	PP2A_PR55_CS	interpro domains	IPR018067	4	1	18521	50	PPP2R2B
1.076e-02	-4.53	Na/K-Atpase_Interacting	interpro domains	IPR008516	4	1	18521	50	NKAIN3
1.076e-02	-4.53	TRPM_tetra	interpro domains	IPR032415	4	1	18521	50	TRPM3
1.076e-02	-4.53	AbLIM_anchor	interpro domains	IPR032402	4	1	18521	50	ABLIM1
1.076e-02	-4.53	P5A-ATPase_N	interpro domains	IPR047819	4	1	18521	50	ATP13A4
1.076e-02	-4.53	CTF/NFI	interpro domains	IPR000647	4	1	18521	50	NFIA
1.076e-02	-4.53	CTF/NFI_DNA-bd_N	interpro domains	IPR019548	4	1	18521	50	NFIA
1.076e-02	-4.53	NHS-like	interpro domains	IPR024845	4	1	18521	50	NHSL1
1.076e-02	-4.53	Desmoplakin_Spectrin-like	interpro domains	IPR041573	4	1	18521	50	MACF1
1.076e-02	-4.53	CTF/NFI_DNA-bd_CS	interpro domains	IPR019739	4	1	18521	50	NFIA
1.076e-02	-4.53	P5B-type_ATPase	interpro domains	IPR047821	4	1	18521	50	ATP13A4
1.076e-02	-4.53	PP2A_PR55	interpro domains	IPR000009	4	1	18521	50	PPP2R2B
1.076e-02	-4.53	Glyco_transf_54	interpro domains	IPR006759	4	1	18521	50	MGAT4C
1.076e-02	-4.53	PCN-like_spectrin-like_rpt	interpro domains	IPR049538	4	1	18521	50	MACF1
1.076e-02	-4.53	Nebulin_repeat	interpro domains	IPR000900	4	1	18521	50	NEBL
1.076e-02	-4.53	TRPM_tetra_sf	interpro domains	IPR037162	4	1	18521	50	TRPM3
1.082e-02	-4.53	Endothelins	Pathway Interaction DB	endothelinpathway	53	2	2226	7	PRKCA,ADCY2
1.088e-02	-4.52	upper_aerodigestive_tract-pharynx-carcinoma-squamous_cell_carcinoma	COSMIC cancer mutations	upper_aerodigestive_tract-pharynx-carcinoma-squamous_cell_carcinoma	1485	10	16828	50	NRG3,FMN2,SORBS1,MACF1,NPAS3,DTNA,GPC5,PARD3B,RYR3,PTPRZ1
1.092e-02	-4.52	Corticotropin Activation of Cortisol Production	SMPDB pathways	SMP0000310	5	1	1369	3	ADCY2
1.092e-02	-4.52	Ion Channel and Phorbal Esters Signaling Pathway	SMPDB pathways	SMP0090032	5	1	1369	3	PRKCA
1.093e-02	-4.52	plasma membrane bounded cell projection morphogenesis	biological process	GO:0120039	491	5	18204	50	BMPR1B,PARD3,CTNND2,GPM6A,PTPRZ1
1.094e-02	-4.52	desmosome assembly	biological process	GO:0002159	4	1	18204	50	PRKCA
1.094e-02	-4.52	ovarian cumulus expansion	biological process	GO:0001550	4	1	18204	50	BMPR1B
1.094e-02	-4.52	regulation of angiotensin-activated signaling pathway	biological process	GO:0110061	4	1	18204	50	PRKCA
1.094e-02	-4.52	leukemia inhibitory factor signaling pathway	biological process	GO:0048861	4	1	18204	50	LIFR
1.094e-02	-4.52	oncostatin-M-mediated signaling pathway	biological process	GO:0038165	4	1	18204	50	LIFR
1.094e-02	-4.52	trans-synaptic signaling by BDNF	biological process	GO:0099191	4	1	18204	50	NTRK2
1.094e-02	-4.52	brain-derived neurotrophic factor receptor signaling pathway	biological process	GO:0031547	4	1	18204	50	NTRK2
1.094e-02	-4.52	positive regulation of mesenchymal stem cell differentiation	biological process	GO:2000741	4	1	18204	50	SOX5
1.105e-02	-4.51	kidney	COSMIC cancer mutations	kidney	15380	50	16828	50	ADCY2,FMN2,SLC1A3,SORBS1,SLC4A4,ZBTB20,GLIS3,ITPR2,PARD3,RORA,PITPNC1,LIFR,GPM6A,FBXL7,MGAT4C,PARD3B,SOX5,RYR3,MAML2,DTNA,NTRK2,PTPRZ1,SLC1A2,NHSL1,MACF1,NTM,ABLIM1,NKAIN3,NFIA,TRPM3,SPARCL1,AQP4,MSI2,CSGALNACT1,QKI,CDH20,RFX4,NRG3,NEBL,TRPS1,LSAMP,PPP2R2B,PRKCA,DCLK2,BMPR1B,SASH1,NPAS3,CTNND2,GPC5,ATP13A4
1.106e-02	-4.50	chondroitin biosynthesis	BIOCYC pathways	META_PWY-6566	5	1	902	2	CSGALNACT1
1.110e-02	-4.50	cellular homeostasis	biological process	GO:0019725	689	6	18204	50	ZBTB20,ATP13A4,SLC1A3,AQP4,RYR3,SLC4A4
1.110e-02	-4.50	VTN (vitronectin)	protein interactions	7448	180	3	19454	50	PRKCA,NFIA,PPP2R2B
1.111e-02	-4.50	thyroid-carcinoma	COSMIC cancer mutations	thyroid-carcinoma	4126	20	16828	50	PARD3,PTPRZ1,LSAMP,ADCY2,DTNA,ITPR2,GLIS3,SPARCL1,TRPM3,NFIA,RYR3,SOX5,ATP13A4,AQP4,SASH1,GPC5,TRPS1,CTNND2,MACF1,LIFR
1.137e-02	-4.48	monoatomic cation channel activity	molecular function	GO:0005261	331	4	18094	48	ITPR2,RYR3,TRPM3,GPM6A
1.138e-02	-4.48	Sorb	smart domains	SM00459	3	1	9717	37	SORBS1
1.138e-02	-4.48	MamL-1	smart domains	SM01275	3	1	9717	37	MAML2
1.138e-02	-4.48	PLP	smart domains	SM00002	3	1	9717	37	GPM6A
1.138e-02	-4.48	cell projection morphogenesis	biological process	GO:0048858	496	5	18204	50	PARD3,BMPR1B,PTPRZ1,GPM6A,CTNND2
1.140e-02	-4.47	positive regulation of cell differentiation	biological process	GO:0045597	906	7	18204	50	QKI,MACF1,BMPR1B,NTRK2,SOX5,PRKCA,PTPRZ1
1.143e-02	-4.47	human chr14q13.1	chromosome location	human chr14q13.1	6	1	26134	50	NPAS3
1.143e-02	-4.47	human chr4q34.2	chromosome location	human chr4q34.2	6	1	26134	50	GPM6A
1.144e-02	-4.47	MYELINPLP	prints domains	PR00214	3	1	5227	20	GPM6A
1.144e-02	-4.47	INSP3RECEPTR	prints domains	PR00779	3	1	5227	20	ITPR2
1.144e-02	-4.47	NTKRECEPTOR	prints domains	PR01939	3	1	5227	20	NTRK2
1.144e-02	-4.47	RORNUCRECPTR	prints domains	PR01293	3	1	5227	20	RORA
1.144e-02	-4.47	RYANODINER	prints domains	PR00795	3	1	5227	20	RYR3
1.144e-02	-4.47	PRPH (peripherin)	protein interactions	5630	182	3	19454	50	PPP2R2B,SORBS1,ABLIM1
1.145e-02	-4.47	establishment or maintenance of apical/basal cell polarity	biological process	GO:0035088	59	2	18204	50	PARD3B,PARD3
1.145e-02	-4.47	establishment or maintenance of bipolar cell polarity	biological process	GO:0061245	59	2	18204	50	PARD3,PARD3B
1.145e-02	-4.47	endochondral bone morphogenesis	biological process	GO:0060350	59	2	18204	50	CSGALNACT1,BMPR1B
1.148e-02	-4.47	Signaling by BRAF and RAF fusions	REACTOME pathways	R-HSA-6802952	60	2	10285	28	MACF1,QKI
1.163e-02	-4.45	pancreas-carcinoma	COSMIC cancer mutations	pancreas-carcinoma	14770	49	16828	50	QKI,CSGALNACT1,RFX4,CDH20,MSI2,NEBL,NRG3,TRPS1,BMPR1B,PPP2R2B,LSAMP,DCLK2,PRKCA,ATP13A4,SASH1,CTNND2,GPC5,NPAS3,PARD3,SLC1A3,ADCY2,FMN2,ZBTB20,GLIS3,ITPR2,SLC4A4,SORBS1,MGAT4C,FBXL7,GPM6A,RYR3,PARD3B,SOX5,PITPNC1,RORA,LIFR,PTPRZ1,SLC1A2,NTRK2,MAML2,SPARCL1,TRPM3,NFIA,NKAIN3,AQP4,NHSL1,ABLIM1,NTM,MACF1
1.175e-02	-4.44	skeletal system development	biological process	GO:0001501	500	5	18204	50	BMPR1B,CSGALNACT1,SOX5,TRPS1,NFIA
1.178e-02	-4.44	SH3_2	pfam domains	PF07653	61	2	17795	48	SASH1,SORBS1
1.179e-02	-4.44	VSX1 (visual system homeobox 1)	protein interactions	30813	64	2	19454	50	TRPS1,NFIA
1.179e-02	-4.44	SYNC (syncoilin, intermediate filament protein)	protein interactions	81493	64	2	19454	50	DTNA,MAML2
1.182e-02	-4.44	regulation of glucose import	biological process	GO:0046324	60	2	18204	50	SORBS1,SLC1A2
1.182e-02	-4.44	proteoglycan biosynthetic process	biological process	GO:0030166	60	2	18204	50	BMPR1B,CSGALNACT1
1.182e-02	-4.44	protein homotetramerization	biological process	GO:0051289	60	2	18204	50	AQP4,RYR3
1.184e-02	-4.44	TRPM, tetramerisation domain	gene3d domains	1.20.5.1010	4	1	14470	43	TRPM3
1.184e-02	-4.44	-	gene3d domains	1.20.58.1060	4	1	14470	43	MACF1
1.185e-02	-4.44	Ca2+ pathway	REACTOME pathways	R-HSA-4086398	61	2	10285	28	ITPR2,PRKCA
1.192e-02	-4.43	chemical homeostasis	biological process	GO:0048878	914	7	18204	50	RYR3,AQP4,RORA,SLC4A4,SLC1A3,ATP13A4,ZBTB20
1.198e-02	-4.42	parathyroid-carcinoma	COSMIC cancer mutations	parathyroid-carcinoma	300	4	16828	50	GPC5,RYR3,TRPS1,MACF1
1.200e-02	-4.42	Erythroid Transcription Factor GATA-1, subunit A	gene3d domains	3.30.50.10	56	2	14470	43	TRPS1,RORA
1.222e-02	-4.40	neoplasm	COSMIC cancer mutations	neoplasm	14787	49	16828	50	SASH1,CTNND2,GPC5,NPAS3,ATP13A4,PPP2R2B,LSAMP,DCLK2,PRKCA,BMPR1B,NEBL,NRG3,TRPS1,MSI2,QKI,CSGALNACT1,RFX4,CDH20,NHSL1,NTM,ABLIM1,MACF1,SPARCL1,TRPM3,NFIA,NKAIN3,AQP4,DTNA,MAML2,SLC1A2,PTPRZ1,NTRK2,RORA,LIFR,FBXL7,MGAT4C,GPM6A,RYR3,SOX5,PARD3B,ADCY2,FMN2,SLC1A3,ZBTB20,GLIS3,ITPR2,SORBS1,SLC4A4,PARD3
1.223e-02	-4.40	cellular response to organonitrogen compound	biological process	GO:0071417	505	5	18204	50	ITPR2,SLC1A2,SORBS1,SLC1A3,RYR3
1.230e-02	-4.40	KLF5 (KLF transcription factor 5)	protein interactions	688	187	3	19454	50	NFIA,TRPS1,PRKCA
1.233e-02	-4.40	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-peripheral_T_cell_lymphoma_unspecified	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-peripheral_T_cell_lymphoma_unspecified	162	3	16828	50	MACF1,ITPR2,RYR3
1.239e-02	-4.39	oligodendroglioma_Grade_III	COSMIC cancer mutations	oligodendroglioma_Grade_III	303	4	16828	50	MGAT4C,MACF1,GLIS3,PTPRZ1
1.248e-02	-4.38	cellular component biogenesis	biological process	GO:0044085	2716	14	18204	50	SORBS1,PARD3,CDH20,TRPM3,AQP4,RFX4,FMN2,GPM6A,ABLIM1,NRG3,RYR3,SLC1A2,NEBL,PRKCA
1.248e-02	-4.38	HNF1B (HNF1 homeobox B)	protein interactions	6928	188	3	19454	50	SOX5,NFIA,TRPS1
1.250e-02	-4.38	MAML1 (mastermind like transcriptional coactivator 1)	protein interactions	9794	66	2	19454	50	NFIA,MAML2
1.253e-02	-4.38	SH3_9	pfam domains	PF14604	63	2	17795	48	NEBL,SORBS1
1.259e-02	-4.38	regulation of carbohydrate catabolic process	biological process	GO:0043470	62	2	18204	50	ZBTB20,SLC4A4
1.260e-02	-4.37	Hippo signaling pathway	KEGG pathways	ko04390	154	3	7161	23	BMPR1B,PPP2R2B,PARD3
1.260e-02	-4.37	Hippo signaling pathway	KEGG pathways	hsa04390	154	3	7161	23	BMPR1B,PPP2R2B,PARD3
1.269e-02	-4.37	liver-carcinoma-hepatocellular_carcinoma	COSMIC cancer mutations	liver-carcinoma-hepatocellular_carcinoma	14800	49	16828	50	FMN2,ADCY2,SLC1A3,SORBS1,SLC4A4,ITPR2,ZBTB20,GLIS3,PARD3,RORA,PITPNC1,LIFR,GPM6A,MGAT4C,FBXL7,RYR3,SOX5,PARD3B,MAML2,DTNA,NTRK2,PTPRZ1,SLC1A2,NHSL1,MACF1,NTM,ABLIM1,NFIA,NKAIN3,SPARCL1,TRPM3,AQP4,QKI,CSGALNACT1,RFX4,CDH20,NRG3,NEBL,TRPS1,PPP2R2B,LSAMP,PRKCA,DCLK2,BMPR1B,SASH1,GPC5,CTNND2,NPAS3,ATP13A4
1.269e-02	-4.37	hepatocellular_carcinoma	COSMIC cancer mutations	hepatocellular_carcinoma	14800	49	16828	50	BMPR1B,LSAMP,PPP2R2B,PRKCA,DCLK2,ATP13A4,SASH1,NPAS3,GPC5,CTNND2,CSGALNACT1,QKI,CDH20,RFX4,NRG3,NEBL,TRPS1,NTRK2,SLC1A2,PTPRZ1,MAML2,DTNA,NKAIN3,NFIA,TRPM3,SPARCL1,AQP4,NHSL1,MACF1,NTM,ABLIM1,PARD3,SLC1A3,ADCY2,FMN2,SORBS1,SLC4A4,GLIS3,ITPR2,ZBTB20,GPM6A,FBXL7,MGAT4C,SOX5,PARD3B,RYR3,RORA,PITPNC1,LIFR
1.279e-02	-4.36	CFHR3 (complement factor H related 3)	protein interactions	10878	5	1	19454	50	PRKCA
1.279e-02	-4.36	Rhoj (ras homolog family member J)	protein interactions	80837	5	1	19454	50	BMPR1B
1.279e-02	-4.36	RFX4 (regulatory factor X4)	protein interactions	5992	5	1	19454	50	RFX4
1.279e-02	-4.36	Wwp2 (WW domain containing E3 ubiquitin protein ligase 2)	protein interactions	66894	5	1	19454	50	GLIS3
1.279e-02	-4.36	Rras2 (related RAS viral (r-ras) oncogene 2)	protein interactions	66922	5	1	19454	50	BMPR1B
1.279e-02	-4.36	Rab6b (RAB6B, member RAS oncogene family)	protein interactions	270192	5	1	19454	50	BMPR1B
1.279e-02	-4.36	DLX3 (distal-less homeobox 3)	protein interactions	1747	5	1	19454	50	PRKCA
1.279e-02	-4.36	SUI2 (translation initiation factor eIF2 subunit alpha)	protein interactions	853463	5	1	19454	50	PRKCA
1.279e-02	-4.36	TRPM6 (transient receptor potential cation channel subfamily M member 6)	protein interactions	140803	5	1	19454	50	TRPM3
1.279e-02	-4.36	Rab38 (RAB38, member RAS oncogene family)	protein interactions	72433	5	1	19454	50	BMPR1B
1.279e-02	-4.36	GABRR2 (gamma-aminobutyric acid type A receptor subunit rho2)	protein interactions	2570	5	1	19454	50	PRKCA
1.279e-02	-4.36	Cdk4 (cyclin dependent kinase 4)	protein interactions	12567	5	1	19454	50	BMPR1B
1.279e-02	-4.36	Rhobtb1 (Rho-related BTB domain containing 1)	protein interactions	69288	5	1	19454	50	BMPR1B
1.279e-02	-4.36	SLC10A3 (solute carrier family 10 member 3)	protein interactions	8273	5	1	19454	50	SORBS1
1.282e-02	-4.36	regulation of small molecule metabolic process	biological process	GO:0062012	331	4	18204	50	ZBTB20,SORBS1,SLC4A4,RORA
1.287e-02	-4.35	PARD6A (par-6 family cell polarity regulator alpha)	protein interactions	50855	67	2	19454	50	PARD3,PRKCA
1.310e-02	-4.34	Dopamine Activation of Neurological Reward System	SMPDB pathways	SMP0000308	6	1	1369	3	ADCY2
1.310e-02	-4.34	Intracellular Signalling Through PGD2 receptor and Prostaglandin D2	SMPDB pathways	SMP0000343	6	1	1369	3	ADCY2
1.310e-02	-4.34	Phospholipase C Signaling Pathway	SMPDB pathways	SMP0063783	6	1	1369	3	PRKCA
1.313e-02	-4.33	response to endogenous stimulus	biological process	GO:0009719	1402	9	18204	50	NFIA,SLC1A3,SORBS1,ITPR2,RYR3,BMPR1B,NTRK2,SLC1A2,SOX5
1.314e-02	-4.33	inorganic ion transmembrane transport	biological process	GO:0098660	715	6	18204	50	RYR3,SLC1A3,GPM6A,TRPM3,ITPR2,SLC4A4
1.318e-02	-4.33	main axon	cellular component	GO:0044304	68	2	19108	49	SLC1A2,PARD3
1.320e-02	-4.33	neurotrophin receptor activity	molecular function	GO:0005030	5	1	18094	48	NTRK2
1.320e-02	-4.33	transforming growth factor beta receptor activity, type I	molecular function	GO:0005025	5	1	18094	48	BMPR1B
1.320e-02	-4.33	parathyroid	COSMIC cancer mutations	parathyroid	476	5	16828	50	GPM6A,MACF1,TRPS1,RYR3,GPC5
1.323e-02	-4.33	CXADR (CXADR Ig-like cell adhesion molecule)	protein interactions	1525	357	4	19454	50	MACF1,PARD3,NEBL,SORBS1
1.324e-02	-4.32	PLCH1 (phospholipase C eta 1)	protein interactions	23007	68	2	19454	50	NTRK2,PARD3
1.327e-02	-4.32	L-amino acid transmembrane transporter activity	molecular function	GO:0015179	66	2	18094	48	SLC1A2,SLC1A3
1.332e-02	-4.32	cell division	biological process	GO:0051301	516	5	18204	50	PARD3,SOX5,FMN2,PARD3B,FBXL7
1.335e-02	-4.32	camera-type eye development	biological process	GO:0043010	335	4	18204	50	GPM6A,NFIA,NTRK2,BMPR1B
1.337e-02	-4.31	actin filament bundle assembly	biological process	GO:0051017	64	2	18204	50	SORBS1,FMN2
1.338e-02	-4.31	peripheral_T_cell_lymphoma_unspecified	COSMIC cancer mutations	peripheral_T_cell_lymphoma_unspecified	167	3	16828	50	RYR3,ITPR2,MACF1
1.339e-02	-4.31	POF1B (POF1B actin binding protein)	protein interactions	79983	193	3	19454	50	NKAIN3,PPP2R2B,CSGALNACT1
1.339e-02	-4.31	PR55_2	prosite domains	PS01025	4	1	12186	41	PPP2R2B
1.339e-02	-4.31	PR55_1	prosite domains	PS01024	4	1	12186	41	PPP2R2B
1.339e-02	-4.31	NEBULIN	prosite domains	PS51216	4	1	12186	41	NEBL
1.339e-02	-4.31	CTF_NFI_1	prosite domains	PS00349	4	1	12186	41	NFIA
1.339e-02	-4.31	CTF_NFI_2	prosite domains	PS51080	4	1	12186	41	NFIA
1.342e-02	-4.31	IP_trans	pfam domains	PF02121	5	1	17795	48	PITPNC1
1.342e-02	-4.31	FOLN	pfam domains	PF09289	5	1	17795	48	SPARCL1
1.343e-02	-4.31	BBP-like	interpro domains	IPR045071	5	1	18521	50	QKI
1.343e-02	-4.31	Na/HCO3_transpt	interpro domains	IPR003024	5	1	18521	50	SLC4A4
1.343e-02	-4.31	P-type_TPase_V	interpro domains	IPR006544	5	1	18521	50	ATP13A4
1.343e-02	-4.31	PI_transfer	interpro domains	IPR001666	5	1	18521	50	PITPNC1
1.343e-02	-4.31	Follistatin/Osteonectin_EGF	interpro domains	IPR015369	5	1	18521	50	SPARCL1
1.346e-02	-4.31	cell-cell junction organization	biological process	GO:0045216	181	3	18204	50	PRKCA,CDH20,PARD3
1.350e-02	-4.30	ovary-carcinoma-clear_cell_carcinoma	COSMIC cancer mutations	ovary-carcinoma-clear_cell_carcinoma	665	6	16828	50	NTRK2,LIFR,PRKCA,DCLK2,BMPR1B,SPARCL1
1.354e-02	-4.30	NGF-independant TRKA activation	REACTOME pathways	R-HSA-187024	5	1	10285	28	NTRK2
1.354e-02	-4.30	Disinhibition of SNARE formation	REACTOME pathways	R-HSA-114516	5	1	10285	28	PRKCA
1.362e-02	-4.30	cell body	cellular component	GO:0044297	556	5	19108	49	CTNND2,SLC1A2,BMPR1B,GPM6A,SLC1A3
1.366e-02	-4.29	ciliary neurotrophic factor-mediated signaling pathway	biological process	GO:0070120	5	1	18204	50	LIFR
1.366e-02	-4.29	polar body extrusion after meiotic divisions	biological process	GO:0040038	5	1	18204	50	FMN2
1.366e-02	-4.29	negative regulation of chondrocyte proliferation	biological process	GO:1902731	5	1	18204	50	BMPR1B
1.366e-02	-4.29	synaptic signaling via neuropeptide	biological process	GO:0099538	5	1	18204	50	NTRK2
1.379e-02	-4.28	RAC1 (Rac family small GTPase 1)	protein interactions	5879	1005	7	19454	50	PARD3,PPP2R2B,PRKCA,MACF1,FMN2,DTNA,SLC1A3
1.387e-02	-4.28	clear_cell_carcinoma	COSMIC cancer mutations	clear_cell_carcinoma	669	6	16828	50	SPARCL1,BMPR1B,DCLK2,LIFR,PRKCA,NTRK2
1.390e-02	-4.28	cellular component organization or biogenesis	biological process	GO:0071840	5850	24	18204	50	SORBS1,PITPNC1,RFX4,AQP4,TRPM3,SPARCL1,GPM6A,PRKCA,CSGALNACT1,BMPR1B,NRG3,CDH20,PARD3,MACF1,NFIA,DCLK2,ABLIM1,FMN2,PARD3B,SLC1A2,NEBL,RYR3,CTNND2,PTPRZ1
1.391e-02	-4.28	brain development	biological process	GO:0007420	724	6	18204	50	SLC1A2,RFX4,NTRK2,RORA,NRG3,DCLK2
1.401e-02	-4.27	Neuronal System	REACTOME pathways	R-HSA-112316	349	4	10285	28	PRKCA,SLC1A2,ADCY2,SLC1A3
1.407e-02	-4.26	RAB35 (RAB35, member RAS oncogene family)	protein interactions	11021	559	5	19454	50	DTNA,SLC1A3,FMN2,PARD3,MACF1
1.416e-02	-4.26	temporoparietal	COSMIC cancer mutations	temporoparietal	61	2	16828	50	RYR3,PARD3
1.418e-02	-4.26	L-alpha-amino acid transmembrane transport	biological process	GO:1902475	66	2	18204	50	SLC1A3,SLC1A2
1.433e-02	-4.25	NFIX (nuclear factor I X)	protein interactions	4784	198	3	19454	50	TRPS1,NFIA,SOX5
1.436e-02	-4.24	other	COSMIC cancer mutations	other	14843	49	16828	50	BMPR1B,PPP2R2B,LSAMP,PRKCA,DCLK2,ATP13A4,SASH1,GPC5,CTNND2,NPAS3,QKI,CSGALNACT1,RFX4,CDH20,MSI2,NRG3,NEBL,TRPS1,NTRK2,SLC1A2,PTPRZ1,MAML2,DTNA,NFIA,NKAIN3,SPARCL1,TRPM3,AQP4,NHSL1,MACF1,NTM,ABLIM1,PARD3,SLC1A3,FMN2,ADCY2,SORBS1,SLC4A4,ZBTB20,ITPR2,GLIS3,GPM6A,MGAT4C,FBXL7,RYR3,SOX5,PARD3B,RORA,LIFR
1.437e-02	-4.24	AKR7L (aldo-keto reductase family 7 like (gene/pseudogene))	protein interactions	246181	71	2	19454	50	MACF1,PARD3
1.437e-02	-4.24	CRYBG1 (crystallin beta-gamma domain containing 1)	protein interactions	202	71	2	19454	50	CSGALNACT1,SPARCL1
1.437e-02	-4.24	HEPHL1 (hephaestin like 1)	protein interactions	341208	71	2	19454	50	CSGALNACT1,PPP2R2B
1.442e-02	-4.24	Downstream signal transduction	REACTOME pathways	R-HSA-186763	352	4	10285	28	NRG3,PRKCA,ADCY2,ITPR2
1.445e-02	-4.24	testis-germ_cell_tumour-non_seminoma	COSMIC cancer mutations	testis-germ_cell_tumour-non_seminoma	487	5	16828	50	DCLK2,MACF1,NTRK2,PRKCA,BMPR1B
1.448e-02	-4.23	cell differentiation	biological process	GO:0030154	3645	17	18204	50	PARD3,NTM,DCLK2,NFIA,QKI,SLC1A3,SOX5,FMN2,GPM6A,BMPR1B,NEBL,RORA,NTRK2,MSI2,PTPRZ1,NHSL1,CTNND2
1.460e-02	-4.23	cellular developmental process	biological process	GO:0048869	3648	17	18204	50	RORA,NTRK2,BMPR1B,NEBL,MSI2,PTPRZ1,NHSL1,CTNND2,FMN2,GPM6A,SOX5,PARD3,NTM,DCLK2,SLC1A3,QKI,NFIA
1.476e-02	-4.22	SEMG2 (semenogelin 2)	protein interactions	6407	72	2	19454	50	PRKCA,PPP2R2B
1.476e-02	-4.22	Ppp1cb (protein phosphatase 1 catalytic subunit beta)	protein interactions	19046	72	2	19454	50	ABLIM1,PARD3
1.476e-02	-4.22	PPP3CC (protein phosphatase 3 catalytic subunit gamma)	protein interactions	5533	72	2	19454	50	BMPR1B,PARD3B
1.490e-02	-4.21	LIM	pfam domains	PF00412	69	2	17795	48	NEBL,ABLIM1
1.491e-02	-4.21	DBN1 (drebrin 1)	protein interactions	1627	370	4	19454	50	SOX5,PPP2R2B,PRKCA,ABLIM1
1.498e-02	-4.20	DAP12 signaling	REACTOME pathways	R-HSA-2424491	356	4	10285	28	ADCY2,PRKCA,NRG3,ITPR2
1.501e-02	-4.20	actin filament bundle organization	biological process	GO:0061572	68	2	18204	50	FMN2,SORBS1
1.505e-02	-4.20	non_seminoma	COSMIC cancer mutations	non_seminoma	492	5	16828	50	BMPR1B,PRKCA,NTRK2,MACF1,DCLK2
1.510e-02	-4.19	adrenal_gland-adrenal_gland-adrenal_cortical_carcinoma-functioning	COSMIC cancer mutations	adrenal_gland-adrenal_gland-adrenal_cortical_carcinoma-functioning	1803	11	16828	50	TRPM3,RFX4,PTPRZ1,SLC1A2,SOX5,NTRK2,NHSL1,FMN2,NRG3,ZBTB20,MAML2
1.510e-02	-4.19	functioning	COSMIC cancer mutations	functioning	1803	11	16828	50	RFX4,SLC1A2,PTPRZ1,SOX5,NTRK2,TRPM3,ZBTB20,MAML2,NHSL1,FMN2,NRG3
1.512e-02	-4.19	FEV (FEV transcription factor, ETS family member)	protein interactions	54738	202	3	19454	50	SOX5,NFIA,TRPS1
1.515e-02	-4.19	NEBU	smart domains	SM00227	4	1	9717	37	NEBL
1.522e-02	-4.19	PP2APR55	prints domains	PR00600	4	1	5227	20	PPP2R2B
1.523e-02	-4.18	haematopoietic_and_lymphoid_tissue-central_nervous_system-lymphoid_neoplasm-primary_central_nervous_system_lymphoma	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue-central_nervous_system-lymphoid_neoplasm-primary_central_nervous_system_lymphoma	683	6	16828	50	ZBTB20,PARD3B,MACF1,PARD3,SASH1,NRG3
1.523e-02	-4.18	primary_central_nervous_system_lymphoma	COSMIC cancer mutations	primary_central_nervous_system_lymphoma	683	6	16828	50	MACF1,ZBTB20,SASH1,NRG3,PARD3B,PARD3
1.527e-02	-4.18	Vasopressin Regulation of Water Homeostasis	SMPDB pathways	SMP0000322	7	1	1369	3	ADCY2
1.527e-02	-4.18	g-Secretase Mediated ErbB4 Signalling Pathway	SMPDB pathways	SMP0089975	7	1	1369	3	PRKCA
1.529e-02	-4.18	PAR polarity complex	cellular component	GO:0120157	6	1	19108	49	PARD3
1.532e-02	-4.18	ARMS2 (age-related maculopathy susceptibility 2)	protein interactions	387715	6	1	19454	50	PRKCA
1.532e-02	-4.18	PBP2 (Pbp2p)	protein interactions	852533	6	1	19454	50	QKI
1.532e-02	-4.18	Fancl (Fanconi anemia, complementation group L)	protein interactions	67030	6	1	19454	50	BMPR1B
1.532e-02	-4.18	Itch (itchy, E3 ubiquitin protein ligase)	protein interactions	16396	6	1	19454	50	GLIS3
1.532e-02	-4.18	SOX11 (SRY-box transcription factor 11)	protein interactions	6664	6	1	19454	50	SOX5
1.532e-02	-4.18	Csnk1d (casein kinase 1, delta)	protein interactions	64462	6	1	19454	50	PRKCA
1.532e-02	-4.18	GDF6 (growth differentiation factor 6)	protein interactions	392255	6	1	19454	50	BMPR1B
1.532e-02	-4.18	Zbtb2 (zinc finger and BTB domain containing 2)	protein interactions	381990	6	1	19454	50	SORBS1
1.532e-02	-4.18	DAZ4 (deleted in azoospermia 4)	protein interactions	57135	6	1	19454	50	QKI
1.532e-02	-4.18	ADCY1 (adenylate cyclase 1)	protein interactions	107	6	1	19454	50	ADCY2
1.532e-02	-4.18	DRP2 (dystrophin related protein 2)	protein interactions	1821	6	1	19454	50	DTNA
1.532e-02	-4.18	Map2k3 (mitogen-activated protein kinase kinase 3)	protein interactions	26397	6	1	19454	50	BMPR1B
1.532e-02	-4.18	CYRIA (CYFIP related Rac1 interactor A)	protein interactions	81553	6	1	19454	50	GPM6A
1.532e-02	-4.18	SLC12A5 (solute carrier family 12 member 5)	protein interactions	57468	6	1	19454	50	GPM6A
1.532e-02	-4.18	Rhod (ras homolog family member D)	protein interactions	11854	6	1	19454	50	BMPR1B
1.532e-02	-4.18	TPPP3 (tubulin polymerization promoting protein family member 3)	protein interactions	51673	6	1	19454	50	PPP2R2B
1.532e-02	-4.18	SOX1 (SRY-box transcription factor 1)	protein interactions	6656	6	1	19454	50	SOX5
1.532e-02	-4.18	LIF (LIF interleukin 6 family cytokine)	protein interactions	3976	6	1	19454	50	LIFR
1.532e-02	-4.18	Tiam2 (T cell lymphoma invasion and metastasis 2)	protein interactions	24001	6	1	19454	50	DTNA
1.541e-02	-4.17	GJA1 (gap junction protein alpha 1)	protein interactions	2697	572	5	19454	50	PARD3,MACF1,PRKCA,ITPR2,DTNA
1.552e-02	-4.17	CASK (calcium/calmodulin dependent serine protein kinase)	protein interactions	8573	204	3	19454	50	ABLIM1,PARD3B,DTNA
1.552e-02	-4.17	NFIC (nuclear factor I C)	protein interactions	4782	204	3	19454	50	SOX5,TRPS1,NFIA
1.560e-02	-4.16	Long-term depression	KEGG pathways	ko04730	60	2	7161	23	ITPR2,PRKCA
1.560e-02	-4.16	Long-term depression	KEGG pathways	hsa04730	60	2	7161	23	PRKCA,ITPR2
1.572e-02	-4.15	UTRN (utrophin)	protein interactions	7402	205	3	19454	50	PARD3,SASH1,DTNA
1.576e-02	-4.15	Znf_LIM	interpro domains	IPR001781	71	2	18521	50	ABLIM1,NEBL
1.581e-02	-4.15	glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity	molecular function	GO:0047238	6	1	18094	48	CSGALNACT1
1.581e-02	-4.15	sodium:bicarbonate symporter activity	molecular function	GO:0008510	6	1	18094	48	SLC4A4
1.581e-02	-4.15	calcium-induced calcium release activity	molecular function	GO:0048763	6	1	18094	48	RYR3
1.581e-02	-4.15	ciliary neurotrophic factor receptor binding	molecular function	GO:0005127	6	1	18094	48	LIFR
1.598e-02	-4.14	cell adhesion molecule binding	molecular function	GO:0050839	560	5	18094	48	MACF1,CTNND2,PTPRZ1,CDH20,PRKCA
1.608e-02	-4.13	GAS2	pfam domains	PF02187	6	1	17795	48	MACF1
1.608e-02	-4.13	Adcy_cons_dom	pfam domains	PF06327	6	1	17795	48	ADCY2
1.608e-02	-4.13	EF-hand_2	pfam domains	PF09068	6	1	17795	48	DTNA
1.608e-02	-4.13	SH3_10	pfam domains	PF17902	6	1	17795	48	MACF1
1.608e-02	-4.13	Plectin	pfam domains	PF00681	6	1	17795	48	MACF1
1.608e-02	-4.13	EF-hand_3	pfam domains	PF09069	6	1	17795	48	DTNA
1.608e-02	-4.13	Glypican	pfam domains	PF01153	6	1	17795	48	GPC5
1.609e-02	-4.13	Desmoplakin_SH3	interpro domains	IPR041615	6	1	18521	50	MACF1
1.609e-02	-4.13	Glypican_CS	interpro domains	IPR019803	6	1	18521	50	GPC5
1.609e-02	-4.13	GAR_dom	interpro domains	IPR003108	6	1	18521	50	MACF1
1.609e-02	-4.13	GAR_dom_sf	interpro domains	IPR036534	6	1	18521	50	MACF1
1.609e-02	-4.13	EF-hand_dom_typ2	interpro domains	IPR015154	6	1	18521	50	DTNA
1.609e-02	-4.13	GLI-like	interpro domains	IPR043359	6	1	18521	50	GLIS3
1.609e-02	-4.13	EF-hand_dom_typ1	interpro domains	IPR015153	6	1	18521	50	DTNA
1.609e-02	-4.13	Glypican	interpro domains	IPR001863	6	1	18521	50	GPC5
1.609e-02	-4.13	Adcy_conserved_dom	interpro domains	IPR009398	6	1	18521	50	ADCY2
1.614e-02	-4.13	Signaling by EGFR	REACTOME pathways	R-HSA-177929	364	4	10285	28	ITPR2,ADCY2,NRG3,PRKCA
1.618e-02	-4.12	protein homooligomerization	biological process	GO:0051260	194	3	18204	50	RYR3,AQP4,SLC1A2
1.623e-02	-4.12	Activation of TRKA receptors	REACTOME pathways	R-HSA-187015	6	1	10285	28	NTRK2
1.627e-02	-4.12	sarcoplasmic reticulum	cellular component	GO:0016529	76	2	19108	49	ITPR2,RYR3
1.628e-02	-4.12	lung-carcinoid-endocrine_tumour	COSMIC cancer mutations	lung-carcinoid-endocrine_tumour	502	5	16828	50	BMPR1B,SASH1,DCLK2,PRKCA,NTRK2
1.629e-02	-4.12	MKRN2 (makorin ring finger protein 2)	protein interactions	23609	380	4	19454	50	BMPR1B,PARD3,MACF1,PRKCA
1.635e-02	-4.11	MIR200A (microRNA 200a)	protein interactions	406983	76	2	19454	50	QKI,MSI2
1.637e-02	-4.11	ERBB4-ERBB4 signaling pathway	biological process	GO:0038138	6	1	18204	50	NRG3
1.637e-02	-4.11	gamma-aminobutyric acid biosynthetic process	biological process	GO:0009449	6	1	18204	50	SLC1A3
1.637e-02	-4.11	positive regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway	biological process	GO:0106071	6	1	18204	50	PRKCA
1.637e-02	-4.11	regulation of protein autoubiquitination	biological process	GO:1902498	6	1	18204	50	SASH1
1.637e-02	-4.11	establishment of meiotic spindle localization	biological process	GO:0051295	6	1	18204	50	FMN2
1.637e-02	-4.11	fused antrum stage	biological process	GO:0048165	6	1	18204	50	BMPR1B
1.637e-02	-4.11	intracellular water homeostasis	biological process	GO:0009992	6	1	18204	50	AQP4
1.637e-02	-4.11	mammary gland formation	biological process	GO:0060592	6	1	18204	50	NRG3
1.637e-02	-4.11	asymmetric neuroblast division	biological process	GO:0055059	6	1	18204	50	SOX5
1.670e-02	-4.09	KIF20A (kinesin family member 20A)	protein interactions	10112	1044	7	19454	50	RORA,ABLIM1,MACF1,NEBL,MSI2,ITPR2,PARD3
1.672e-02	-4.09	regulation of ATP metabolic process	biological process	GO:1903578	72	2	18204	50	SLC4A4,ZBTB20
1.675e-02	-4.09	ABI1 (abl interactor 1)	protein interactions	10006	210	3	19454	50	SORBS1,SLC1A3,NHSL1
1.676e-02	-4.09	ADGRL2 (adhesion G protein-coupled receptor L2)	protein interactions	23266	77	2	19454	50	NTRK2,PARD3
1.677e-02	-4.09	cellular response to organic substance	biological process	GO:0071310	1716	10	18204	50	SORBS1,SLC1A3,ZBTB20,ITPR2,RYR3,AQP4,RORA,SLC1A2,LIFR,ADCY2
1.680e-02	-4.09	skin-ear-carcinoma-squamous_cell_carcinoma	COSMIC cancer mutations	skin-ear-carcinoma-squamous_cell_carcinoma	506	5	16828	50	LIFR,NPAS3,ZBTB20,MGAT4C,SPARCL1
1.685e-02	-4.08	adenoid_cystic_carcinoma	COSMIC cancer mutations	adenoid_cystic_carcinoma	1123	8	16828	50	PRKCA,LIFR,MAML2,CTNND2,RORA,NTRK2,RYR3,MGAT4C
1.689e-02	-4.08	Diseases of signal transduction	REACTOME pathways	R-HSA-5663202	369	4	10285	28	MAML2,QKI,NRG3,MACF1
1.694e-02	-4.08	signal transduction	biological process	GO:0007165	4637	20	18204	50	FMN2,ITPR2,NRG3,DTNA,RYR3,CTNND2,NTRK2,RORA,BMPR1B,PRKCA,ADCY2,PITPNC1,DCLK2,MACF1,SORBS1,MAML2,NFIA,PARD3,SPARCL1,LIFR
1.706e-02	-4.07	bone-femur-other-chondroblastoma	COSMIC cancer mutations	bone-femur-other-chondroblastoma	183	3	16828	50	GPC5,RYR3,NRG3
1.709e-02	-4.07	human chr4q22.3	chromosome location	human chr4q22.3	9	1	26134	50	BMPR1B
1.711e-02	-4.07	Oncogenic MAPK signaling	REACTOME pathways	R-HSA-6802957	74	2	10285	28	MACF1,QKI
1.716e-02	-4.07	ErbB Signaling Pathway	WikiPathways	WP673	54	2	5310	20	PRKCA,NRG3
1.716e-02	-4.07	vasculogenesis	biological process	GO:0001570	73	2	18204	50	QKI,NTRK2
1.716e-02	-4.07	MARCKS (myristoylated alanine rich protein kinase C substrate)	protein interactions	4082	588	5	19454	50	MACF1,ABLIM1,PRKCA,SLC1A3,DTNA
1.717e-02	-4.06	ATP2B3 (ATPase plasma membrane Ca2+ transporting 3)	protein interactions	492	78	2	19454	50	CSGALNACT1,GPM6A
1.717e-02	-4.06	MIR34C (microRNA 34c)	protein interactions	407042	78	2	19454	50	QKI,MSI2
1.717e-02	-4.06	Nedd4 (NEDD4 E3 ubiquitin protein ligase)	protein interactions	25489	78	2	19454	50	BMPR1B,NTRK2
1.717e-02	-4.06	ANKRD40 (ankyrin repeat domain 40)	protein interactions	91369	78	2	19454	50	MSI2,SOX5
1.719e-02	-4.06	DAP12 interactions	REACTOME pathways	R-HSA-2172127	371	4	10285	28	ADCY2,PRKCA,NRG3,ITPR2
1.744e-02	-4.05	Intracellular Signalling Through Prostacyclin Receptor and Prostacyclin	SMPDB pathways	SMP0000354	8	1	1369	3	ADCY2
1.749e-02	-4.05	Muscle contraction	REACTOME pathways	R-HSA-397014	204	3	10285	28	SORBS1,ITPR2,RYR3
1.759e-02	-4.04	PRDM1 (PR/SET domain 1)	protein interactions	639	79	2	19454	50	NFIA,TRPS1
1.761e-02	-4.04	positive regulation of gliogenesis	biological process	GO:0014015	74	2	18204	50	PTPRZ1,QKI
1.767e-02	-4.04	mannosyl-glycoprotein N-acetylglucosaminyltransferases	BIOCYC pathways	META_PWY-7426	8	1	902	2	MGAT4C
1.770e-02	-4.03	autonomic_ganglia-paraganglioma-benign	COSMIC cancer mutations	autonomic_ganglia-paraganglioma-benign	6	1	16828	50	NHSL1
1.770e-02	-4.03	Plakin repeat	gene3d domains	3.90.1290.10	6	1	14470	43	MACF1
1.770e-02	-4.03	Gas2-like domain	gene3d domains	3.30.920.20	6	1	14470	43	MACF1
1.786e-02	-4.03	SASH3 (SAM and SH3 domain containing 3)	protein interactions	54440	7	1	19454	50	BMPR1B
1.786e-02	-4.03	SLC16A5 (solute carrier family 16 member 5)	protein interactions	9121	7	1	19454	50	PTPRZ1
1.786e-02	-4.03	Pum2 (pumilio RNA-binding family member 2)	protein interactions	80913	7	1	19454	50	QKI
1.786e-02	-4.03	Fbxo3 (F-box protein 3)	protein interactions	57443	7	1	19454	50	BMPR1B
1.786e-02	-4.03	ZBTB45 (zinc finger and BTB domain containing 45)	protein interactions	84878	7	1	19454	50	ZBTB20
1.786e-02	-4.03	Smad7 (SMAD family member 7)	protein interactions	17131	7	1	19454	50	BMPR1B
1.786e-02	-4.03	RGMB (repulsive guidance molecule BMP co-receptor b)	protein interactions	285704	7	1	19454	50	BMPR1B
1.786e-02	-4.03	Uhmk1 (U2AF homology motif (UHM) kinase 1)	protein interactions	16589	7	1	19454	50	BMPR1B
1.786e-02	-4.03	ABCC12 (ATP binding cassette subfamily C member 12)	protein interactions	94160	7	1	19454	50	NPAS3
1.786e-02	-4.03	Smurf1 (SMAD specific E3 ubiquitin protein ligase 1)	protein interactions	75788	7	1	19454	50	GLIS3
1.797e-02	-4.02	Signaling by PDGF	REACTOME pathways	R-HSA-186797	376	4	10285	28	ADCY2,NRG3,PRKCA,ITPR2
1.801e-02	-4.02	GJB1 (gap junction protein beta 1)	protein interactions	2705	80	2	19454	50	MSI2,PRKCA
1.804e-02	-4.01	ATP2B1 (ATPase plasma membrane Ca2+ transporting 1)	protein interactions	490	216	3	19454	50	NTRK2,PRKCA,PARD3
1.820e-02	-4.01	salivary_gland	COSMIC cancer mutations	salivary_gland	1139	8	16828	50	MGAT4C,RYR3,NTRK2,RORA,CTNND2,LIFR,PRKCA,MAML2
1.821e-02	-4.01	adrenal_gland	COSMIC cancer mutations	adrenal_gland	2628	14	16828	50	MAML2,ZBTB20,CTNND2,NRG3,FMN2,ADCY2,NHSL1,NTRK2,SOX5,SLC1A2,PTPRZ1,RFX4,CSGALNACT1,TRPM3
1.840e-02	-4.00	actin filament binding	molecular function	GO:0051015	211	3	18094	48	MACF1,ABLIM1,NEBL
1.843e-02	-3.99	phosphatidic acid transfer activity	molecular function	GO:1990050	7	1	18094	48	PITPNC1
1.843e-02	-3.99	SOX17 (SRY-box transcription factor 17)	protein interactions	64321	81	2	19454	50	TRPS1,NFIA
1.843e-02	-3.99	KLHL15 (kelch like family member 15)	protein interactions	80311	81	2	19454	50	DCLK2,PPP2R2B
1.865e-02	-3.98	Ion channel transport	REACTOME pathways	R-HSA-983712	209	3	10285	28	ATP13A4,RYR3,TRPM3
1.865e-02	-3.98	Protein_kinase_ATP_BS	interpro domains	IPR017441	377	4	18521	50	NTRK2,BMPR1B,DCLK2,PRKCA
1.871e-02	-3.98	TRIM29 (tripartite motif containing 29)	protein interactions	23650	219	3	19454	50	PPP2R2B,PRKCA,NKAIN3
1.873e-02	-3.98	TGF_beta_GS	pfam domains	PF08515	7	1	17795	48	BMPR1B
1.873e-02	-3.98	SPARC_Ca_bdg	pfam domains	PF10591	7	1	17795	48	SPARCL1
1.875e-02	-3.98	Plakophilin/d_Catenin	interpro domains	IPR028435	7	1	18521	50	CTNND2
1.875e-02	-3.98	Plakin_repeat_sf	interpro domains	IPR035915	7	1	18521	50	MACF1
1.875e-02	-3.98	GS_dom	interpro domains	IPR003605	7	1	18521	50	BMPR1B
1.875e-02	-3.98	SPARC/Testican_Ca-bd-dom	interpro domains	IPR019577	7	1	18521	50	SPARCL1
1.875e-02	-3.98	Hematopoietin_rcpt_Gp130_CS	interpro domains	IPR003529	7	1	18521	50	LIFR
1.875e-02	-3.98	Plectin_repeat	interpro domains	IPR001101	7	1	18521	50	MACF1
1.875e-02	-3.98	Aquaporin_transptr	interpro domains	IPR034294	7	1	18521	50	AQP4
1.875e-02	-3.98	head development	biological process	GO:0060322	774	6	18204	50	RORA,RFX4,SLC1A2,NTRK2,NRG3,DCLK2
1.897e-02	-3.96	human chr9p24.2	chromosome location	human chr9p24.2	10	1	26134	50	GLIS3
1.897e-02	-3.96	human chr12p11.23	chromosome location	human chr12p11.23	10	1	26134	50	ITPR2
1.898e-02	-3.96	positive regulation of axonogenesis	biological process	GO:0050772	77	2	18204	50	MACF1,NTRK2
1.898e-02	-3.96	neural retina development	biological process	GO:0003407	77	2	18204	50	GPM6A,NTRK2
1.898e-02	-3.96	BMP signaling pathway	biological process	GO:0030509	77	2	18204	50	NFIA,BMPR1B
1.899e-02	-3.96	NAHCO3TRSPRT	prints domains	PR01232	5	1	5227	20	SLC4A4
1.899e-02	-3.96	PITRANSFER	prints domains	PR00391	5	1	5227	20	PITPNC1
1.907e-02	-3.96	regulation of 3'-UTR-mediated mRNA stabilization	biological process	GO:1905868	7	1	18204	50	QKI
1.907e-02	-3.96	cellular response to magnesium ion	biological process	GO:0071286	7	1	18204	50	RYR3
1.907e-02	-3.96	positive regulation of transcription of Notch receptor target	biological process	GO:0007221	7	1	18204	50	MAML2
1.907e-02	-3.96	interneuron migration from the subpallium to the cortex	biological process	GO:0021830	7	1	18204	50	NRG3
1.907e-02	-3.96	chromosome movement towards spindle pole	biological process	GO:0051305	7	1	18204	50	FMN2
1.907e-02	-3.96	regulation of oligodendrocyte progenitor proliferation	biological process	GO:0070445	7	1	18204	50	PTPRZ1
1.907e-02	-3.96	glial cell fate specification	biological process	GO:0021780	7	1	18204	50	NFIA
1.907e-02	-3.96	parallel actin filament bundle assembly	biological process	GO:0030046	7	1	18204	50	FMN2
1.912e-02	-3.96	Glycosaminoglycan biosynthesis, chondroitin sulfate backbone	KEGG pathways	M00058	6	1	7161	23	CSGALNACT1
1.912e-02	-3.96	Glycosaminoglycan biosynthesis, chondroitin sulfate backbone	KEGG pathways	hsa_M00058	6	1	7161	23	CSGALNACT1
1.922e-02	-3.95	Long-term potentiation	KEGG pathways	hsa04720	67	2	7161	23	ITPR2,PRKCA
1.922e-02	-3.95	Long-term potentiation	KEGG pathways	ko04720	67	2	7161	23	ITPR2,PRKCA
1.930e-02	-3.95	PAX2 (paired box 2)	protein interactions	5076	83	2	19454	50	TRPS1,NFIA
1.944e-02	-3.94	regulation of glucose transmembrane transport	biological process	GO:0010827	78	2	18204	50	SLC1A2,SORBS1
1.954e-02	-3.94	SH3-like_dom_sf	interpro domains	IPR036028	212	3	18521	50	SORBS1,SASH1,NEBL
1.954e-02	-3.94	transmembrane receptor protein kinase activity	molecular function	GO:0019199	81	2	18094	48	NTRK2,BMPR1B
1.960e-02	-3.93	ovary-carcinoma	COSMIC cancer mutations	ovary-carcinoma	933	7	16828	50	DCLK2,ITPR2,MACF1,PRKCA,PPP2R2B,NTRK2,BMPR1B
1.961e-02	-3.93	Excitatory Neural Signalling Through 5-HTR 6 and Serotonin	SMPDB pathways	SMP0000312	9	1	1369	3	ADCY2
1.961e-02	-3.93	Excitatory Neural Signalling Through 5-HTR 7 and Serotonin	SMPDB pathways	SMP0000311	9	1	1369	3	ADCY2
1.961e-02	-3.93	Nitric Oxide Signaling Pathway	SMPDB pathways	SMP0063777	9	1	1369	3	PRKCA
1.961e-02	-3.93	Intracellular Signalling Through FSH Receptor and Follicle Stimulating Hormone	SMPDB pathways	SMP0000333	9	1	1369	3	ADCY2
1.961e-02	-3.93	Intracellular Signalling Through Histamine H2 Receptor and Histamine	SMPDB pathways	SMP0000335	9	1	1369	3	ADCY2
1.961e-02	-3.93	Excitatory Neural Signalling Through 5-HTR 4 and Serotonin	SMPDB pathways	SMP0000309	9	1	1369	3	ADCY2
1.962e-02	-3.93	TGM1 (transglutaminase 1)	protein interactions	7051	223	3	19454	50	PPP2R2B,CSGALNACT1,QKI
1.973e-02	-3.93	regulation of neurogenesis	biological process	GO:0050767	377	4	18204	50	NTRK2,QKI,MACF1,PTPRZ1
1.978e-02	-3.92	cytoskeleton organization	biological process	GO:0007010	1251	8	18204	50	NEBL,PARD3B,DCLK2,FMN2,ABLIM1,MACF1,SORBS1,PARD3
1.982e-02	-3.92	Regulation of insulin secretion	REACTOME pathways	R-HSA-422356	80	2	10285	28	PRKCA,ITPR2
1.984e-02	-3.92	Cysteine Rich Protein	gene3d domains	2.10.110.10	73	2	14470	43	NEBL,ABLIM1
1.985e-02	-3.92	MAPRE3 (microtubule associated protein RP/EB family member 3)	protein interactions	22924	224	3	19454	50	ABLIM1,MACF1,GPM6A
1.991e-02	-3.92	regulation of glial cell differentiation	biological process	GO:0045685	79	2	18204	50	QKI,PTPRZ1
2.002e-02	-3.91	GLYPICAN	prosite domains	PS01207	6	1	12186	41	GPC5
2.002e-02	-3.91	GAR	prosite domains	PS51460	6	1	12186	41	MACF1
2.003e-02	-3.91	metal ion binding	molecular function	GO:0046872	4239	18	18094	48	PRKCA,BMPR1B,ITPR2,SLC1A3,ADCY2,ABLIM1,GLIS3,ZBTB20,SLC1A2,RYR3,DTNA,MACF1,CSGALNACT1,ATP13A4,MGAT4C,TRPS1,SPARCL1,RORA
2.004e-02	-3.91	somatodendritic compartment	cellular component	GO:0036477	842	6	19108	49	NTRK2,ADCY2,CTNND2,BMPR1B,GPM6A,SLC1A3
2.008e-02	-3.91	KLF3 (KLF transcription factor 3)	protein interactions	51274	225	3	19454	50	SOX5,TRPS1,NFIA
2.018e-02	-3.90	CFAP298 (cilia and flagella associated protein 298)	protein interactions	56683	85	2	19454	50	TRPS1,FMN2
2.034e-02	-3.90	zonula adherens	cellular component	GO:0005915	8	1	19108	49	SORBS1
2.034e-02	-3.90	HFE-transferrin receptor complex	cellular component	GO:1990712	8	1	19108	49	BMPR1B
2.038e-02	-3.89	Prkca (protein kinase C, alpha)	protein interactions	24680	8	1	19454	50	PRKCA
2.038e-02	-3.89	Rps27a (ribosomal protein S27A)	protein interactions	78294	8	1	19454	50	BMPR1B
2.038e-02	-3.89	LHB (luteinizing hormone subunit beta)	protein interactions	3972	8	1	19454	50	NTM
2.038e-02	-3.89	CD163 (CD163 molecule)	protein interactions	9332	8	1	19454	50	PRKCA
2.038e-02	-3.89	Rasd2 (RASD family, member 2)	protein interactions	75141	8	1	19454	50	BMPR1B
2.038e-02	-3.89	INSM1 (INSM transcriptional repressor 1)	protein interactions	3642	8	1	19454	50	SORBS1
2.038e-02	-3.89	Marcks (myristoylated alanine rich protein kinase C substrate)	protein interactions	17118	8	1	19454	50	PRKCA
2.038e-02	-3.89	DEPP1 (DEPP autophagy regulator 1)	protein interactions	11067	8	1	19454	50	QKI
2.038e-02	-3.89	BMP15 (bone morphogenetic protein 15)	protein interactions	9210	8	1	19454	50	BMPR1B
2.042e-02	-3.89	eye development	biological process	GO:0001654	381	4	18204	50	BMPR1B,NTRK2,NFIA,GPM6A
2.055e-02	-3.88	receptor complex	cellular component	GO:0043235	409	4	19108	49	LIFR,BMPR1B,NTRK2,ITPR2
2.063e-02	-3.88	SYNJ1 (synaptojanin 1)	protein interactions	8867	86	2	19454	50	GPM6A,SORBS1
2.063e-02	-3.88	FAM171A1 (family with sequence similarity 171 member A1)	protein interactions	221061	86	2	19454	50	PARD3,NTRK2
2.084e-02	-3.87	dendrite	cellular component	GO:0030425	620	5	19108	49	BMPR1B,GPM6A,ADCY2,CTNND2,NTRK2
2.084e-02	-3.87	testis	COSMIC cancer mutations	testis	733	6	16828	50	NTRK2,PRKCA,MACF1,DCLK2,TRPS1,BMPR1B
2.101e-02	-3.86	EF_hand_dom	interpro domains	IPR002048	218	3	18521	50	SPARCL1,RYR3,MACF1
2.103e-02	-3.86	glutamate binding	molecular function	GO:0016595	8	1	18094	48	SLC1A3
2.103e-02	-3.86	BMP receptor activity	molecular function	GO:0098821	8	1	18094	48	BMPR1B
2.103e-02	-3.86	cellular response to nitrogen compound	biological process	GO:1901699	580	5	18204	50	SORBS1,SLC1A3,RYR3,SLC1A2,ITPR2
2.105e-02	-3.86	glutamatergic synapse	cellular component	GO:0098978	412	4	19108	49	SPARCL1,GPM6A,NRG3,SLC1A2
2.108e-02	-3.86	Kctd5 (potassium channel tetramerisation domain containing 5)	protein interactions	69259	87	2	19454	50	TRPS1,SLC1A3
2.108e-02	-3.86	MIR141 (microRNA 141)	protein interactions	406933	87	2	19454	50	MSI2,QKI
2.108e-02	-3.86	ZNF608 (zinc finger protein 608)	protein interactions	57507	87	2	19454	50	SOX5,NFIA
2.108e-02	-3.86	NHLH1 (nescient helix-loop-helix 1)	protein interactions	4807	87	2	19454	50	TRPS1,NFIA
2.110e-02	-3.86	dendritic tree	cellular component	GO:0097447	622	5	19108	49	BMPR1B,GPM6A,NTRK2,ADCY2,CTNND2
2.113e-02	-3.86	visual system development	biological process	GO:0150063	385	4	18204	50	NTRK2,BMPR1B,GPM6A,NFIA
2.123e-02	-3.85	H1-5 (H1.5 linker histone, cluster member)	protein interactions	3009	412	4	19454	50	MGAT4C,CSGALNACT1,PRKCA,PARD3B
2.138e-02	-3.85	LSDAT_euk	pfam domains	PF18139	8	1	17795	48	TRPM3
2.138e-02	-3.85	VHP	pfam domains	PF02209	8	1	17795	48	ABLIM1
2.138e-02	-3.85	DCX	pfam domains	PF03607	8	1	17795	48	DCLK2
2.138e-02	-3.85	AC_N	pfam domains	PF16214	8	1	17795	48	ADCY2
2.138e-02	-3.85	CHGN	pfam domains	PF05679	8	1	17795	48	CSGALNACT1
2.140e-02	-3.84	AC_N	interpro domains	IPR032628	8	1	18521	50	ADCY2
2.140e-02	-3.84	Plakin	interpro domains	IPR043197	8	1	18521	50	MACF1
2.140e-02	-3.84	Chond_GalNAc	interpro domains	IPR008428	8	1	18521	50	CSGALNACT1
2.140e-02	-3.84	Villin_headpiece	interpro domains	IPR003128	8	1	18521	50	ABLIM1
2.140e-02	-3.84	TRPM_SLOG	interpro domains	IPR041491	8	1	18521	50	TRPM3
2.140e-02	-3.84	Adcy	interpro domains	IPR030672	8	1	18521	50	ADCY2
2.140e-02	-3.84	RFX-like	interpro domains	IPR039779	8	1	18521	50	RFX4
2.140e-02	-3.84	Villin_headpiece_dom_sf	interpro domains	IPR036886	8	1	18521	50	ABLIM1
2.158e-02	-3.84	HuR (ELAVL1) binds and stabilizes mRNA	REACTOME pathways	R-HSA-450520	8	1	10285	28	PRKCA
2.158e-02	-3.84	Release of Hh-Np from the secreting cell	REACTOME pathways	R-HSA-5362798	8	1	10285	28	GPC5
2.177e-02	-3.83	dermatan sulfate proteoglycan biosynthetic process	biological process	GO:0050651	8	1	18204	50	CSGALNACT1
2.177e-02	-3.83	heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process	biological process	GO:0015014	8	1	18204	50	CSGALNACT1
2.177e-02	-3.83	meiotic cytokinesis	biological process	GO:0033206	8	1	18204	50	FMN2
2.177e-02	-3.83	mitotic nuclear membrane disassembly	biological process	GO:0007077	8	1	18204	50	PRKCA
2.177e-02	-3.83	ERBB4 signaling pathway	biological process	GO:0038130	8	1	18204	50	NRG3
2.177e-02	-3.83	cell proliferation in external granule layer	biological process	GO:0021924	8	1	18204	50	RORA
2.177e-02	-3.83	gamma-aminobutyric acid metabolic process	biological process	GO:0009448	8	1	18204	50	SLC1A3
2.177e-02	-3.83	cerebellar granule cell precursor proliferation	biological process	GO:0021930	8	1	18204	50	RORA
2.177e-02	-3.83	cell proliferation in hindbrain	biological process	GO:0021534	8	1	18204	50	RORA
2.177e-02	-3.83	Intracellular Signalling Through LHCGR Receptor and Luteinizing Hormone/Choriogonadotropin	SMPDB pathways	SMP0000338	10	1	1369	3	ADCY2
2.199e-02	-3.82	SERPINB13 (serpin family B member 13)	protein interactions	5275	89	2	19454	50	PPP2R2B,CSGALNACT1
2.199e-02	-3.82	SOX10 (SRY-box transcription factor 10)	protein interactions	6663	89	2	19454	50	TRPS1,NFIA
2.201e-02	-3.82	Adherens junction	KEGG pathways	hsa04520	72	2	7161	23	PARD3,SORBS1
2.201e-02	-3.82	Adherens junction	KEGG pathways	ko04520	72	2	7161	23	SORBS1,PARD3
2.213e-02	-3.81	upper_aerodigestive_tract-head_neck-carcinoma-squamous_cell_carcinoma	COSMIC cancer mutations	upper_aerodigestive_tract-head_neck-carcinoma-squamous_cell_carcinoma	9263	35	16828	50	TRPS1,LIFR,PITPNC1,NEBL,RORA,PARD3B,SOX5,RYR3,FBXL7,MGAT4C,ITPR2,GLIS3,SORBS1,SLC4A4,ADCY2,FMN2,MSI2,CDH20,QKI,GPC5,CTNND2,MACF1,NHSL1,SASH1,TRPM3,NKAIN3,NFIA,DCLK2,PRKCA,MAML2,LSAMP,PPP2R2B,PTPRZ1,NTRK2,BMPR1B
2.221e-02	-3.81	sensory system development	biological process	GO:0048880	391	4	18204	50	NTRK2,BMPR1B,GPM6A,NFIA
2.224e-02	-3.81	HMG20A (high mobility group 20A)	protein interactions	10363	234	3	19454	50	NFIA,SOX5,DTNA
2.233e-02	-3.80	proteoglycan metabolic process	biological process	GO:0006029	84	2	18204	50	BMPR1B,CSGALNACT1
2.233e-02	-3.80	L-amino acid transport	biological process	GO:0015807	84	2	18204	50	SLC1A3,SLC1A2
2.233e-02	-3.80	peripheral nervous system development	biological process	GO:0007422	84	2	18204	50	PARD3,NTRK2
2.237e-02	-3.80	kidney-Wilms_tumour	COSMIC cancer mutations	kidney-Wilms_tumour	545	5	16828	50	FMN2,BMPR1B,DCLK2,NTRK2,PRKCA
2.238e-02	-3.80	acral_lentiginous	COSMIC cancer mutations	acral_lentiginous	745	6	16828	50	PARD3,CSGALNACT1,ATP13A4,CDH20,NRG3,MACF1
2.245e-02	-3.80	oesophagus-carcinoma-adenocarcinoma	COSMIC cancer mutations	oesophagus-carcinoma-adenocarcinoma	13112	45	16828	50	NEBL,NRG3,TRPS1,CSGALNACT1,QKI,CDH20,RFX4,SASH1,NPAS3,CTNND2,GPC5,ATP13A4,LSAMP,PPP2R2B,DCLK2,PRKCA,BMPR1B,RORA,LIFR,MGAT4C,FBXL7,GPM6A,PARD3B,SOX5,RYR3,SLC1A3,ADCY2,FMN2,ZBTB20,ITPR2,GLIS3,SLC4A4,SORBS1,PARD3,NHSL1,NTM,MACF1,TRPM3,SPARCL1,NKAIN3,AQP4,MAML2,SLC1A2,PTPRZ1,NTRK2
2.246e-02	-3.80	SEMG1 (semenogelin 1)	protein interactions	6406	90	2	19454	50	PPP2R2B,PRKCA
2.246e-02	-3.80	CTDSPL (CTD small phosphatase like)	protein interactions	10217	90	2	19454	50	FMN2,DTNA
2.253e-02	-3.79	Wilms_tumour	COSMIC cancer mutations	Wilms_tumour	546	5	16828	50	BMPR1B,FMN2,NTRK2,PRKCA,DCLK2
2.264e-02	-3.79	GAS2	smart domains	SM00243	6	1	9717	37	MACF1
2.272e-02	-3.78	human chr6q26	chromosome location	human chr6q26	12	1	26134	50	QKI
2.275e-02	-3.78	ACTIVIN2R	prints domains	PR00653	6	1	5227	20	BMPR1B
2.283e-02	-3.78	oligodendrocyte differentiation	biological process	GO:0048709	85	2	18204	50	PTPRZ1,NTRK2
2.283e-02	-3.78	chondrocyte differentiation	biological process	GO:0002062	85	2	18204	50	BMPR1B,SOX5
2.285e-02	-3.78	astrocyte end-foot	cellular component	GO:0097450	9	1	19108	49	AQP4
2.285e-02	-3.78	platelet dense tubular network membrane	cellular component	GO:0031095	9	1	19108	49	ITPR2
2.285e-02	-3.78	flotillin complex	cellular component	GO:0016600	9	1	19108	49	SORBS1
2.290e-02	-3.78	IER5 (immediate early response 5)	protein interactions	51278	9	1	19454	50	PPP2R2B
2.290e-02	-3.78	VEPH1 (ventricular zone expressed PH domain containing 1)	protein interactions	79674	9	1	19454	50	BMPR1B
2.290e-02	-3.78	SCTR (secretin receptor)	protein interactions	6344	9	1	19454	50	PRKCA
2.290e-02	-3.78	Ywhag (tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide)	protein interactions	22628	9	1	19454	50	QKI
2.290e-02	-3.78	NRXN2 (neurexin 2)	protein interactions	9379	9	1	19454	50	MACF1
2.290e-02	-3.78	PI3 (peptidase inhibitor 3)	protein interactions	5266	9	1	19454	50	PPP2R2B
2.292e-02	-3.78	FOXI1 (forkhead box I1)	protein interactions	2299	91	2	19454	50	TRPS1,NFIA
2.292e-02	-3.78	DGUOK (deoxyguanosine kinase)	protein interactions	1716	91	2	19454	50	NTM,GPM6A
2.299e-02	-3.77	CAMK2A (calcium/calmodulin dependent protein kinase II alpha)	protein interactions	815	237	3	19454	50	GPM6A,ITPR2,SOX5
2.300e-02	-3.77	-	gene3d domains	2.80.10.50	79	2	14470	43	ITPR2,RYR3
2.330e-02	-3.76	RNF43 (ring finger protein 43)	protein interactions	54894	424	4	19454	50	QKI,MACF1,ABLIM1,PARD3
2.332e-02	-3.76	GS	prosite domains	PS51256	7	1	12186	41	BMPR1B
2.332e-02	-3.76	HEMATOPO_REC_L_F2	prosite domains	PS01353	7	1	12186	41	LIFR
2.334e-02	-3.76	central nervous system neuron development	biological process	GO:0021954	86	2	18204	50	DCLK2,NTRK2
2.339e-02	-3.76	SOX9 (SRY-box transcription factor 9)	protein interactions	6662	92	2	19454	50	NFIA,TRPS1
2.352e-02	-3.75	organic anion transport	biological process	GO:0015711	398	4	18204	50	NTRK2,SLC1A2,SLC4A4,SLC1A3
2.353e-02	-3.75	central_nervous_system-chiasm-glioma-astrocytoma_Grade_I	COSMIC cancer mutations	central_nervous_system-chiasm-glioma-astrocytoma_Grade_I	8	1	16828	50	QKI
2.353e-02	-3.75	Villin headpiece domain	gene3d domains	1.10.950.10	8	1	14470	43	ABLIM1
2.363e-02	-3.75	calcium-dependent protein serine/threonine kinase activity	molecular function	GO:0009931	9	1	18094	48	PRKCA
2.371e-02	-3.74	LIM_DOMAIN_2	prosite domains	PS50023	71	2	12186	41	ABLIM1,NEBL
2.371e-02	-3.74	LIM_DOMAIN_1	prosite domains	PS00478	71	2	12186	41	ABLIM1,NEBL
2.387e-02	-3.74	LGALS7B (galectin 7B)	protein interactions	653499	93	2	19454	50	CSGALNACT1,PPP2R2B
2.387e-02	-3.74	TEX11 (testis expressed 11)	protein interactions	56159	93	2	19454	50	SOX5,QKI
2.387e-02	-3.74	DMRTB1 (DMRT like family B with proline rich C-terminal 1)	protein interactions	63948	93	2	19454	50	MSI2,QKI
2.387e-02	-3.74	MIR19B2 (microRNA 19b-2)	protein interactions	406981	93	2	19454	50	QKI,MSI2
2.387e-02	-3.74	ARHGEF6 (Rac/Cdc42 guanine nucleotide exchange factor 6)	protein interactions	9459	93	2	19454	50	ABLIM1,BMPR1B
2.393e-02	-3.73	NAD+ Signalling and Aging	SMPDB pathways	SMP0084271	11	1	1369	3	RORA
2.401e-02	-3.73	ERBIN (erbb2 interacting protein)	protein interactions	55914	241	3	19454	50	NTRK2,CTNND2,PARD3
2.402e-02	-3.73	RFX_DNA_binding	pfam domains	PF02257	9	1	17795	48	RFX4
2.402e-02	-3.73	Band_3_cyto	pfam domains	PF07565	9	1	17795	48	SLC4A4
2.402e-02	-3.73	Activin_recp	pfam domains	PF01064	9	1	17795	48	BMPR1B
2.404e-02	-3.73	Fol_N	interpro domains	IPR003645	9	1	18521	50	SPARCL1
2.404e-02	-3.73	Activin_recp	interpro domains	IPR000472	9	1	18521	50	BMPR1B
2.404e-02	-3.73	Doublecortin_dom	interpro domains	IPR003533	9	1	18521	50	DCLK2
2.404e-02	-3.73	DNA-bd_RFX	interpro domains	IPR003150	9	1	18521	50	RFX4
2.404e-02	-3.73	Band3_cytoplasmic_dom	interpro domains	IPR013769	9	1	18521	50	SLC4A4
2.425e-02	-3.72	EGFR Transactivation by Gastrin	REACTOME pathways	R-HSA-2179392	9	1	10285	28	PRKCA
2.430e-02	-3.72	protein binding	molecular function	GO:0005515	13983	43	18094	48	NFIA,CTNND2,DTNA,BMPR1B,PARD3,NRG3,SLC4A4,ITPR2,ADCY2,GLIS3,NPAS3,SLC1A2,RORA,LSAMP,SORBS1,QKI,AQP4,DCLK2,MSI2,PTPRZ1,NTM,RYR3,CDH20,MACF1,FBXL7,NTRK2,SLC1A3,PRKCA,ABLIM1,RFX4,PARD3B,SASH1,GPM6A,PITPNC1,NEBL,SPARCL1,MAML2,PPP2R2B,LIFR,GPC5,TRPS1,SOX5,FMN2
2.435e-02	-3.72	GRIN1 (glutamate ionotropic receptor NMDA type subunit 1)	protein interactions	2902	94	2	19454	50	NTRK2,PRKCA
2.435e-02	-3.72	QSER1 (glutamine and serine rich 1)	protein interactions	79832	94	2	19454	50	SOX5,NFIA
2.435e-02	-3.72	FOXP4 (forkhead box P4)	protein interactions	116113	94	2	19454	50	NFIA,SOX5
2.435e-02	-3.72	WWC1 (WW and C2 domain containing 1)	protein interactions	23286	94	2	19454	50	ABLIM1,PRKCA
2.444e-02	-3.71	skin-leg-malignant_melanoma-superficial_spreading	COSMIC cancer mutations	skin-leg-malignant_melanoma-superficial_spreading	210	3	16828	50	ATP13A4,NTM,SLC4A4
2.446e-02	-3.71	polyamine transmembrane transport	biological process	GO:1902047	9	1	18204	50	ATP13A4
2.446e-02	-3.71	release of sequestered calcium ion into cytosol by sarcoplasmic reticulum	biological process	GO:0014808	9	1	18204	50	RYR3
2.450e-02	-3.71	hairy_cell_leukaemia	COSMIC cancer mutations	hairy_cell_leukaemia	1440	9	16828	50	CDH20,RYR3,RFX4,PTPRZ1,FMN2,NEBL,CTNND2,LIFR,MACF1
2.450e-02	-3.71	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-hairy_cell_leukaemia	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-hairy_cell_leukaemia	1440	9	16828	50	LIFR,MACF1,CTNND2,NEBL,FMN2,CDH20,RYR3,PTPRZ1,RFX4
2.456e-02	-3.71	membrane	cellular component	GO:0016020	9220	31	19108	49	CSGALNACT1,PARD3B,DTNA,SORBS1,NRG3,MGAT4C,BMPR1B,GPC5,FMN2,LSAMP,LIFR,GPM6A,NTM,PRKCA,SLC1A3,RYR3,PARD3,PPP2R2B,MACF1,SLC1A2,TRPM3,NKAIN3,ADCY2,CDH20,NTRK2,SLC4A4,CTNND2,PTPRZ1,ATP13A4,ITPR2,AQP4
2.459e-02	-3.71	human chr5p15.1	chromosome location	human chr5p15.1	13	1	26134	50	FBXL7
2.468e-02	-3.70	skeletal system morphogenesis	biological process	GO:0048705	228	3	18204	50	SOX5,CSGALNACT1,BMPR1B
2.474e-02	-3.70	acute_lymphoblastic_leukaemia	COSMIC cancer mutations	acute_lymphoblastic_leukaemia	2197	12	16828	50	ADCY2,DTNA,DCLK2,PRKCA,SLC4A4,BMPR1B,PTPRZ1,NTRK2,TRPS1,NFIA,PARD3B,SOX5
2.487e-02	-3.69	positive regulation of lipid biosynthetic process	biological process	GO:0046889	89	2	18204	50	ZBTB20,SORBS1
2.495e-02	-3.69	axon	cellular component	GO:0030424	650	5	19108	49	DTNA,NTRK2,SLC1A2,PARD3,GPM6A
2.496e-02	-3.69	DNA-binding transcription factor activity, RNA polymerase II-specific	molecular function	GO:0000981	1355	8	18094	48	RORA,NFIA,RFX4,GLIS3,TRPS1,NPAS3,SOX5,ZBTB20
2.498e-02	-3.69	salivary_gland-parotid-carcinoma-adenoid_cystic_carcinoma	COSMIC cancer mutations	salivary_gland-parotid-carcinoma-adenoid_cystic_carcinoma	561	5	16828	50	RYR3,MAML2,NTRK2,LIFR,PRKCA
2.503e-02	-3.69	Oncostatin M Signaling Pathway	WikiPathways	WP2374	66	2	5310	20	LIFR,PRKCA
2.513e-02	-3.68	oesophagus-lower_third-carcinoma-adenocarcinoma	COSMIC cancer mutations	oesophagus-lower_third-carcinoma-adenocarcinoma	6302	26	16828	50	NEBL,NRG3,RORA,TRPS1,MGAT4C,PARD3B,SOX5,RYR3,ADCY2,FMN2,ZBTB20,ITPR2,SORBS1,PARD3,QKI,CDH20,NPAS3,CTNND2,GPC5,MACF1,TRPM3,ATP13A4,AQP4,PRKCA,PTPRZ1,NTRK2
2.521e-02	-3.68	sarcoplasm	cellular component	GO:0016528	96	2	19108	49	ITPR2,RYR3
2.523e-02	-3.68	cation binding	molecular function	GO:0043169	4341	18	18094	48	RYR3,DTNA,MACF1,CSGALNACT1,PRKCA,ITPR2,BMPR1B,SLC1A3,ADCY2,ABLIM1,GLIS3,ZBTB20,SLC1A2,SPARCL1,RORA,ATP13A4,MGAT4C,TRPS1
2.525e-02	-3.68	urinary_tract-bladder-carcinoma	COSMIC cancer mutations	urinary_tract-bladder-carcinoma	14050	47	16828	50	NRG3,NEBL,TRPS1,MSI2,QKI,CSGALNACT1,RFX4,CDH20,SASH1,CTNND2,GPC5,NPAS3,ATP13A4,PPP2R2B,LSAMP,PRKCA,DCLK2,BMPR1B,RORA,PITPNC1,LIFR,GPM6A,MGAT4C,FBXL7,RYR3,PARD3B,SOX5,FMN2,ADCY2,SLC1A3,SORBS1,SLC4A4,ITPR2,ZBTB20,GLIS3,PARD3,MACF1,ABLIM1,NTM,NFIA,SPARCL1,TRPM3,MAML2,DTNA,NTRK2,SLC1A2,PTPRZ1
2.532e-02	-3.68	E7 (E7 protein)	protein interactions	1489369	96	2	19454	50	QKI,SASH1
2.536e-02	-3.67	perineuronal net	cellular component	GO:0072534	10	1	19108	49	PTPRZ1
2.539e-02	-3.67	regulation of purine nucleotide metabolic process	biological process	GO:1900542	90	2	18204	50	ZBTB20,SLC4A4
2.541e-02	-3.67	Vbp1 (von Hippel-Lindau binding protein 1)	protein interactions	22327	10	1	19454	50	ABLIM1
2.541e-02	-3.67	TNP1 (transition protein 1)	protein interactions	7141	10	1	19454	50	PRKCA
2.541e-02	-3.67	BANK1 (B cell scaffold protein with ankyrin repeats 1)	protein interactions	55024	10	1	19454	50	ITPR2
2.541e-02	-3.67	PPY (pancreatic polypeptide)	protein interactions	5539	10	1	19454	50	PRKCA
2.541e-02	-3.67	CALB2 (calbindin 2)	protein interactions	794	10	1	19454	50	GPM6A
2.541e-02	-3.67	Mrpl13 (mitochondrial ribosomal protein L13)	protein interactions	68537	10	1	19454	50	QKI
2.541e-02	-3.67	DEFA1B (defensin alpha 1B)	protein interactions	728358	10	1	19454	50	PPP2R2B
2.541e-02	-3.67	GSG1 (germ cell associated 1)	protein interactions	83445	10	1	19454	50	PITPNC1
2.541e-02	-3.67	Hsp90aa1 (heat shock protein 90, alpha (cytosolic), class A member 1)	protein interactions	15519	10	1	19454	50	QKI
2.541e-02	-3.67	SLC8A2 (solute carrier family 8 member A2)	protein interactions	6543	10	1	19454	50	GPM6A
2.541e-02	-3.67	Smurf2 (SMAD specific E3 ubiquitin protein ligase 2)	protein interactions	66313	10	1	19454	50	GLIS3
2.541e-02	-3.67	P2rx7 (purinergic receptor P2X 7)	protein interactions	29665	10	1	19454	50	PTPRZ1
2.551e-02	-3.67	CCDC8 (coiled-coil domain containing 8)	protein interactions	83987	652	5	19454	50	ITPR2,ABLIM1,MACF1,NTRK2,PRKCA
2.573e-02	-3.66	Post-translational modification: synthesis of GPI-anchored proteins	REACTOME pathways	R-HSA-163125	92	2	10285	28	NTM,LSAMP
2.581e-02	-3.66	BTG3 (BTG anti-proliferation factor 3)	protein interactions	10950	97	2	19454	50	SPARCL1,DCLK2
2.592e-02	-3.65	regulation of nucleotide metabolic process	biological process	GO:0006140	91	2	18204	50	SLC4A4,ZBTB20
2.592e-02	-3.65	response to BMP	biological process	GO:0071772	91	2	18204	50	NFIA,BMPR1B
2.592e-02	-3.65	cellular response to BMP stimulus	biological process	GO:0071773	91	2	18204	50	BMPR1B,NFIA
2.622e-02	-3.64	phosphatidylinositol transfer activity	molecular function	GO:0008526	10	1	18094	48	PITPNC1
2.622e-02	-3.64	calcium-dependent protein kinase activity	molecular function	GO:0010857	10	1	18094	48	PRKCA
2.622e-02	-3.64	polyamine transmembrane transporter activity	molecular function	GO:0015203	10	1	18094	48	ATP13A4
2.622e-02	-3.64	neurotrophin binding	molecular function	GO:0043121	10	1	18094	48	NTRK2
2.625e-02	-3.64	cell surface	cellular component	GO:0009986	896	6	19108	49	LIFR,SLC1A3,SLC1A2,GPC5,SLC4A4,AQP4
2.631e-02	-3.64	MED27 (mediator complex subunit 27)	protein interactions	9442	98	2	19454	50	QKI,SOX5
2.631e-02	-3.64	DNAAF2 (dynein axonemal assembly factor 2)	protein interactions	55172	98	2	19454	50	GPM6A,LSAMP
2.636e-02	-3.64	GS	smart domains	SM00467	7	1	9717	37	BMPR1B
2.636e-02	-3.64	PLEC	smart domains	SM00250	7	1	9717	37	MACF1
2.641e-02	-3.63	positive regulation of nucleobase-containing compound metabolic process	biological process	GO:0045935	2118	11	18204	50	NPAS3,MAML2,QKI,NFIA,ZBTB20,GLIS3,FMN2,RFX4,RORA,BMPR1B,SLC4A4
2.644e-02	-3.63	Doublecortin domain	gene3d domains	3.10.20.230	9	1	14470	43	DCLK2
2.645e-02	-3.63	dermatan sulfate biosynthesis	BIOCYC pathways	HUMAN_PWY-6571	12	1	902	2	CSGALNACT1
2.659e-02	-3.63	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-NK-T_cell_lymphoma	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-NK-T_cell_lymphoma	217	3	16828	50	MGAT4C,RFX4,DTNA
2.661e-02	-3.63	HP	prosite domains	PS51089	8	1	12186	41	ABLIM1
2.661e-02	-3.63	GATA_ZN_FINGER_1	prosite domains	PS00344	8	1	12186	41	TRPS1
2.666e-02	-3.62	PAS_3	pfam domains	PF08447	10	1	17795	48	NPAS3
2.666e-02	-3.62	HCO3_cotransp	pfam domains	PF00955	10	1	17795	48	SLC4A4
2.666e-02	-3.62	Ig_sub2	interpro domains	IPR003598	239	3	18521	50	NTM,LSAMP,NTRK2
2.668e-02	-3.62	Doublecortin_dom_sf	interpro domains	IPR036572	10	1	18521	50	DCLK2
2.668e-02	-3.62	MIP_CS	interpro domains	IPR022357	10	1	18521	50	AQP4
2.668e-02	-3.62	PAS_fold_3	interpro domains	IPR013655	10	1	18521	50	NPAS3
2.668e-02	-3.62	HCO3_transpt_euk	interpro domains	IPR003020	10	1	18521	50	SLC4A4
2.668e-02	-3.62	HCO3_transpt-like_TM_dom	interpro domains	IPR011531	10	1	18521	50	SLC4A4
2.668e-02	-3.62	PTrfase/Anion_transptr	interpro domains	IPR016152	10	1	18521	50	SLC4A4
2.675e-02	-3.62	upper_aerodigestive_tract-lymph_node-carcinoma-adenoid_cystic_carcinoma	COSMIC cancer mutations	upper_aerodigestive_tract-lymph_node-carcinoma-adenoid_cystic_carcinoma	383	4	16828	50	MAML2,LIFR,PRKCA,NTRK2
2.675e-02	-3.62	salivary_gland-carcinoma	COSMIC cancer mutations	salivary_gland-carcinoma	383	4	16828	50	LIFR,PRKCA,NTRK2,MAML2
2.675e-02	-3.62	upper_aerodigestive_tract-mouth-carcinoma-adenoid_cystic_carcinoma	COSMIC cancer mutations	upper_aerodigestive_tract-mouth-carcinoma-adenoid_cystic_carcinoma	383	4	16828	50	MAML2,NTRK2,LIFR,PRKCA
2.675e-02	-3.62	upper_aerodigestive_tract-carcinoma	COSMIC cancer mutations	upper_aerodigestive_tract-carcinoma	383	4	16828	50	MAML2,NTRK2,PRKCA,LIFR
2.675e-02	-3.62	upper_aerodigestive_tract-head_neck-carcinoma-adenoid_cystic_carcinoma	COSMIC cancer mutations	upper_aerodigestive_tract-head_neck-carcinoma-adenoid_cystic_carcinoma	383	4	16828	50	MAML2,LIFR,PRKCA,NTRK2
2.678e-02	-3.62	YWHAE (tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein epsilon)	protein interactions	7531	1150	7	19454	50	SORBS1,PARD3B,PARD3,SASH1,DCLK2,ABLIM1,MACF1
2.680e-02	-3.62	ZFHX3 (zinc finger homeobox 3)	protein interactions	463	99	2	19454	50	TRPS1,SOX5
2.690e-02	-3.62	Acetylcholine regulates insulin secretion	REACTOME pathways	R-HSA-399997	10	1	10285	28	PRKCA
2.690e-02	-3.62	Bicarbonate transporters	REACTOME pathways	R-HSA-425381	10	1	10285	28	SLC4A4
2.690e-02	-3.62	Adenylate cyclase activating pathway	REACTOME pathways	R-HSA-170660	10	1	10285	28	ADCY2
2.690e-02	-3.62	PI3K events in ERBB4 signaling	REACTOME pathways	R-HSA-1250342	10	1	10285	28	NRG3
2.693e-02	-3.61	NCK2 (NCK adaptor protein 2)	protein interactions	8440	252	3	19454	50	NTRK2,NHSL1,SORBS1
2.693e-02	-3.61	CRX (cone-rod homeobox)	protein interactions	1406	252	3	19454	50	TRPS1,NFIA,SOX5
2.714e-02	-3.61	cAMP biosynthetic process	biological process	GO:0006171	10	1	18204	50	ADCY2
2.714e-02	-3.61	release of sequestered calcium ion into cytosol by endoplasmic reticulum	biological process	GO:1903514	10	1	18204	50	RYR3
2.714e-02	-3.61	substrate-independent telencephalic tangential interneuron migration	biological process	GO:0021843	10	1	18204	50	NRG3
2.714e-02	-3.61	neuronal action potential propagation	biological process	GO:0019227	10	1	18204	50	NTRK2
2.714e-02	-3.61	trans-synaptic signaling, modulating synaptic transmission	biological process	GO:0099550	10	1	18204	50	NTRK2
2.714e-02	-3.61	action potential propagation	biological process	GO:0098870	10	1	18204	50	NTRK2
2.714e-02	-3.61	regulation of mesenchymal stem cell differentiation	biological process	GO:2000739	10	1	18204	50	SOX5
2.714e-02	-3.61	desmosome organization	biological process	GO:0002934	10	1	18204	50	PRKCA
2.714e-02	-3.61	cellular response to brain-derived neurotrophic factor stimulus	biological process	GO:1990416	10	1	18204	50	NTRK2
2.714e-02	-3.61	negative regulation of glial cell apoptotic process	biological process	GO:0034351	10	1	18204	50	PRKCA
2.714e-02	-3.61	retinal rod cell development	biological process	GO:0046548	10	1	18204	50	NTRK2
2.714e-02	-3.61	substrate-independent telencephalic tangential migration	biological process	GO:0021826	10	1	18204	50	NRG3
2.719e-02	-3.61	extrinsic component of plasma membrane	cellular component	GO:0019897	100	2	19108	49	DTNA,CDH20
2.719e-02	-3.60	response to organic cyclic compound	biological process	GO:0014070	843	6	18204	50	ADCY2,RORA,SLC1A2,RYR3,ITPR2,SLC1A3
2.738e-02	-3.60	cellular response to chemical stimulus	biological process	GO:0070887	2411	12	18204	50	ZBTB20,SORBS1,SLC1A3,AQP4,LIFR,FMN2,ITPR2,RYR3,ADCY2,SLC1A2,RORA,NTRK2
2.776e-02	-3.58	DYNLL2 (dynein light chain LC8-type 2)	protein interactions	140735	255	3	19454	50	NHSL1,NFIA,TRPS1
2.781e-02	-3.58	PRKCG (protein kinase C gamma)	protein interactions	5582	101	2	19454	50	PRKCA,PARD3
2.781e-02	-3.58	EVPL (envoplakin)	protein interactions	2125	101	2	19454	50	PPP2R2B,NKAIN3
2.786e-02	-3.58	perisynaptic extracellular matrix	cellular component	GO:0098966	11	1	19108	49	PTPRZ1
2.786e-02	-3.58	platelet dense tubular network	cellular component	GO:0031094	11	1	19108	49	ITPR2
2.792e-02	-3.58	Cobll1 (Cobl-like 1)	protein interactions	319876	11	1	19454	50	ABLIM1
2.792e-02	-3.58	IRAG1 (inositol 1,4,5-triphosphate receptor associated 1)	protein interactions	10335	11	1	19454	50	ITPR2
2.792e-02	-3.58	Gtf2e2 (general transcription factor II E, polypeptide 2 (beta subunit))	protein interactions	68153	11	1	19454	50	NHSL1
2.792e-02	-3.58	Batf3 (basic leucine zipper transcription factor, ATF-like 3)	protein interactions	381319	11	1	19454	50	MACF1
2.792e-02	-3.58	ITPKA (inositol-trisphosphate 3-kinase A)	protein interactions	3706	11	1	19454	50	PRKCA
2.792e-02	-3.58	SYN3 (synapsin III)	protein interactions	8224	11	1	19454	50	GPM6A
2.792e-02	-3.58	IL7 (interleukin 7)	protein interactions	3574	11	1	19454	50	QKI
2.792e-02	-3.58	DAZ1 (deleted in azoospermia 1)	protein interactions	1617	11	1	19454	50	QKI
2.792e-02	-3.58	Wipi2 (WD repeat domain, phosphoinositide interacting 2)	protein interactions	74781	11	1	19454	50	MACF1
2.792e-02	-3.58	TMEM53 (transmembrane protein 53)	protein interactions	79639	11	1	19454	50	PRKCA
2.795e-02	-3.58	parotid	COSMIC cancer mutations	parotid	578	5	16828	50	MAML2,LIFR,NTRK2,PRKCA,RYR3
2.802e-02	-3.58	RNA polymerase II transcription regulatory region sequence-specific DNA binding	molecular function	GO:0000977	1385	8	18094	48	RORA,NFIA,ZBTB20,GLIS3,TRPS1,NPAS3,SOX5,RFX4
2.807e-02	-3.57	calcium ion transmembrane import into cytosol	biological process	GO:0097553	95	2	18204	50	RYR3,ITPR2
2.824e-02	-3.57	Succinate Signalling During Inflammation	SMPDB pathways	SMP0084634	13	1	1369	3	PRKCA
2.832e-02	-3.56	PDLIM7 (PDZ and LIM domain 7)	protein interactions	9260	257	3	19454	50	PRKCA,PARD3,ABLIM1
2.832e-02	-3.56	human chr8q12.3	chromosome location	human chr8q12.3	15	1	26134	50	NKAIN3
2.832e-02	-3.56	human chr10p12.31	chromosome location	human chr10p12.31	15	1	26134	50	NEBL
2.832e-02	-3.56	MIR7-1 (microRNA 7-1)	protein interactions	407043	102	2	19454	50	QKI,MSI2
2.858e-02	-3.56	Rap1 signaling pathway	KEGG pathways	ko04015	210	3	7161	23	PARD3,ADCY2,PRKCA
2.858e-02	-3.56	Rap1 signaling pathway	KEGG pathways	hsa04015	210	3	7161	23	PARD3,ADCY2,PRKCA
2.880e-02	-3.55	histone H3 kinase activity	molecular function	GO:0140996	11	1	18094	48	PRKCA
2.880e-02	-3.55	sulfur amino acid transmembrane transporter activity	molecular function	GO:0000099	11	1	18094	48	SLC1A2
2.884e-02	-3.55	ZDHHC5 (zinc finger DHHC-type palmitoyltransferase 5)	protein interactions	25921	103	2	19454	50	NTRK2,PARD3
2.884e-02	-3.55	RAB6B (RAB6B, member RAS oncogene family)	protein interactions	51560	103	2	19454	50	BMPR1B,GPM6A
2.884e-02	-3.55	CSGALNACT2 (chondroitin sulfate N-acetylgalactosaminyltransferase 2)	protein interactions	55454	103	2	19454	50	MGAT4C,CSGALNACT1
2.884e-02	-3.55	pancreas-other-adenoma	COSMIC cancer mutations	pancreas-other-adenoma	224	3	16828	50	BMPR1B,CTNND2,PRKCA
2.893e-02	-3.54	amino acid transmembrane transporter activity	molecular function	GO:0015171	100	2	18094	48	SLC1A2,SLC1A3
2.916e-02	-3.54	monoatomic ion channel activity	molecular function	GO:0005216	441	4	18094	48	TRPM3,GPM6A,RYR3,ITPR2
2.917e-02	-3.53	amino acid transmembrane transport	biological process	GO:0003333	97	2	18204	50	SLC1A3,SLC1A2
2.917e-02	-3.53	NK-T_cell_lymphoma	COSMIC cancer mutations	NK-T_cell_lymphoma	225	3	16828	50	DTNA,RFX4,MGAT4C
2.926e-02	-3.53	biliary_tract-bile_duct-carcinoma-adenocarcinoma	COSMIC cancer mutations	biliary_tract-bile_duct-carcinoma-adenocarcinoma	15095	49	16828	50	MSI2,QKI,CSGALNACT1,RFX4,CDH20,NEBL,NRG3,TRPS1,PPP2R2B,LSAMP,DCLK2,PRKCA,BMPR1B,SASH1,CTNND2,GPC5,NPAS3,ATP13A4,SLC1A3,FMN2,ADCY2,ZBTB20,ITPR2,GLIS3,SORBS1,SLC4A4,PARD3,PITPNC1,RORA,LIFR,FBXL7,MGAT4C,GPM6A,RYR3,SOX5,PARD3B,DTNA,MAML2,PTPRZ1,SLC1A2,NTRK2,NHSL1,ABLIM1,NTM,MACF1,SPARCL1,TRPM3,NFIA,AQP4
2.926e-02	-3.53	bile_duct	COSMIC cancer mutations	bile_duct	15095	49	16828	50	NPAS3,GPC5,CTNND2,SASH1,ATP13A4,PRKCA,DCLK2,LSAMP,PPP2R2B,BMPR1B,TRPS1,NRG3,NEBL,MSI2,CDH20,RFX4,CSGALNACT1,QKI,MACF1,NTM,ABLIM1,NHSL1,AQP4,NFIA,TRPM3,SPARCL1,MAML2,DTNA,NTRK2,PTPRZ1,SLC1A2,LIFR,RORA,PITPNC1,PARD3B,SOX5,RYR3,GPM6A,MGAT4C,FBXL7,SLC4A4,SORBS1,ZBTB20,ITPR2,GLIS3,ADCY2,SLC1A3,FMN2,PARD3
2.930e-02	-3.53	urinary_tract	COSMIC cancer mutations	urinary_tract	14112	47	16828	50	PARD3,SLC4A4,SORBS1,GLIS3,ITPR2,ZBTB20,FMN2,ADCY2,SLC1A3,RYR3,SOX5,PARD3B,GPM6A,FBXL7,MGAT4C,LIFR,RORA,PITPNC1,NTRK2,SLC1A2,PTPRZ1,MAML2,DTNA,NFIA,SPARCL1,TRPM3,MACF1,NTM,ABLIM1,RFX4,CDH20,QKI,CSGALNACT1,MSI2,TRPS1,NRG3,NEBL,BMPR1B,PRKCA,DCLK2,PPP2R2B,LSAMP,ATP13A4,GPC5,CTNND2,NPAS3,SASH1
2.930e-02	-3.53	bladder	COSMIC cancer mutations	bladder	14112	47	16828	50	MACF1,ABLIM1,NTM,NFIA,SPARCL1,TRPM3,MAML2,DTNA,NTRK2,PTPRZ1,SLC1A2,LIFR,RORA,PITPNC1,RYR3,SOX5,PARD3B,GPM6A,MGAT4C,FBXL7,SORBS1,SLC4A4,GLIS3,ZBTB20,ITPR2,SLC1A3,ADCY2,FMN2,PARD3,CTNND2,GPC5,NPAS3,SASH1,ATP13A4,PRKCA,DCLK2,PPP2R2B,LSAMP,BMPR1B,TRPS1,NRG3,NEBL,MSI2,RFX4,CDH20,QKI,CSGALNACT1
2.931e-02	-3.53	Tyr_kinase_rcpt_2_CS	interpro domains	IPR002011	11	1	18521	50	NTRK2
2.933e-02	-3.53	chiasm	COSMIC cancer mutations	chiasm	10	1	16828	50	QKI
2.933e-02	-3.53	Helical hairpin bin	gene3d domains	1.10.287.570	10	1	14470	43	SLC4A4
2.958e-02	-3.52	VIRMA (vir like m6A methyltransferase associated)	protein interactions	25962	2914	13	19454	50	SASH1,PARD3,SORBS1,PRKCA,LIFR,TRPS1,PARD3B,MAML2,ITPR2,ZBTB20,MACF1,ABLIM1,NHSL1
2.968e-02	-3.52	intracellular monoatomic cation homeostasis	biological process	GO:0030003	428	4	18204	50	SLC4A4,RYR3,SLC1A3,ATP13A4
2.974e-02	-3.52	LIM	smart domains	SM00132	71	2	9717	37	NEBL,ABLIM1
2.978e-02	-3.51	adrenal_cortical_carcinoma	COSMIC cancer mutations	adrenal_cortical_carcinoma	2256	12	16828	50	NRG3,NHSL1,FMN2,MAML2,CTNND2,ZBTB20,TRPM3,NTRK2,RFX4,PTPRZ1,SLC1A2,SOX5
2.979e-02	-3.51	active transmembrane transporter activity	molecular function	GO:0022804	444	4	18094	48	SLC1A2,SLC4A4,ATP13A4,SLC1A3
2.981e-02	-3.51	cellular response to caffeine	biological process	GO:0071313	11	1	18204	50	RYR3
2.981e-02	-3.51	pyramidal neuron development	biological process	GO:0021860	11	1	18204	50	DCLK2
2.981e-02	-3.51	ectodermal placode formation	biological process	GO:0060788	11	1	18204	50	NRG3
2.981e-02	-3.51	heparin biosynthetic process	biological process	GO:0030210	11	1	18204	50	CSGALNACT1
2.981e-02	-3.51	glutamate secretion	biological process	GO:0014047	11	1	18204	50	NTRK2
2.981e-02	-3.51	negative regulation of neuron migration	biological process	GO:2001223	11	1	18204	50	NRG3
2.981e-02	-3.51	ectodermal placode morphogenesis	biological process	GO:0071697	11	1	18204	50	NRG3
2.981e-02	-3.51	polyamine transport	biological process	GO:0015846	11	1	18204	50	ATP13A4
2.981e-02	-3.51	intracellular mRNA localization	biological process	GO:0008298	11	1	18204	50	QKI
2.981e-02	-3.51	antral ovarian follicle growth	biological process	GO:0001547	11	1	18204	50	BMPR1B
2.981e-02	-3.51	PPP2CA (protein phosphatase 2 catalytic subunit alpha)	protein interactions	5515	458	4	19454	50	NHSL1,CSGALNACT1,PPP2R2B,BMPR1B
2.989e-02	-3.51	DC	prosite domains	PS50309	9	1	12186	41	DCLK2
2.989e-02	-3.51	RFX_DBD	prosite domains	PS51526	9	1	12186	41	RFX4
2.998e-02	-3.51	Insulin secretion	KEGG pathways	hsa04911	85	2	7161	23	PRKCA,ADCY2
2.998e-02	-3.51	ErbB signaling pathway	KEGG pathways	hsa04012	85	2	7161	23	NRG3,PRKCA
2.998e-02	-3.51	ErbB signaling pathway	KEGG pathways	ko04012	85	2	7161	23	PRKCA,NRG3
3.007e-02	-3.50	VHP	smart domains	SM00153	8	1	9717	37	ABLIM1
3.022e-02	-3.50	GATAZNFINGER	prints domains	PR00619	8	1	5227	20	TRPS1
3.028e-02	-3.50	bone morphogenesis	biological process	GO:0060349	99	2	18204	50	BMPR1B,CSGALNACT1
3.034e-02	-3.50	response to wounding	biological process	GO:0009611	431	4	18204	50	SLC1A3,MACF1,NFIA,SLC1A2
3.034e-02	-3.50	trans-synaptic signaling	biological process	GO:0099537	431	4	18204	50	DTNA,SLC1A3,NTRK2,SLC1A2
3.035e-02	-3.49	synapse-associated extracellular matrix	cellular component	GO:0099535	12	1	19108	49	PTPRZ1
3.040e-02	-3.49	USP6NL (USP6 N-terminal like)	protein interactions	9712	106	2	19454	50	PARD3,NTRK2
3.042e-02	-3.49	XK (X-linked Kx blood group antigen, Kell and VPS13A binding protein)	protein interactions	7504	12	1	19454	50	PRKCA
3.042e-02	-3.49	BAMBI (BMP and activin membrane bound inhibitor)	protein interactions	25805	12	1	19454	50	BMPR1B
3.042e-02	-3.49	CTF1 (cardiotrophin 1)	protein interactions	1489	12	1	19454	50	LIFR
3.042e-02	-3.49	OAS2 (2'-5'-oligoadenylate synthetase 2)	protein interactions	4939	12	1	19454	50	SASH1
3.042e-02	-3.49	Pard6b (par-6 family cell polarity regulator beta)	protein interactions	58220	12	1	19454	50	PARD3
3.042e-02	-3.49	NTF4 (neurotrophin 4)	protein interactions	4909	12	1	19454	50	NTRK2
3.042e-02	-3.49	CA4 (carbonic anhydrase 4)	protein interactions	762	12	1	19454	50	SLC4A4
3.042e-02	-3.49	ART4 (ADP-ribosyltransferase 4 (inactive) (Dombrock blood group))	protein interactions	420	12	1	19454	50	GPM6A
3.042e-02	-3.49	Ctnnbl1 (catenin, beta like 1)	protein interactions	66642	12	1	19454	50	PRKCA
3.058e-02	-3.49	Visual phototransduction	REACTOME pathways	R-HSA-2187338	101	2	10285	28	GPC5,PRKCA
3.085e-02	-3.48	regulation of cell differentiation	biological process	GO:0045595	1622	9	18204	50	QKI,MACF1,PRKCA,SOX5,RORA,NTRK2,BMPR1B,PTPRZ1,TRPS1
3.124e-02	-3.47	blood vessel morphogenesis	biological process	GO:0048514	435	4	18204	50	PRKCA,NTRK2,RORA,QKI
3.138e-02	-3.46	inositol 1,4,5 trisphosphate binding	molecular function	GO:0070679	12	1	18094	48	ITPR2
3.138e-02	-3.46	adenylate cyclase binding	molecular function	GO:0008179	12	1	18094	48	ADCY2
3.142e-02	-3.46	regulation of glucose metabolic process	biological process	GO:0010906	101	2	18204	50	RORA,SORBS1
3.147e-02	-3.46	CLASP1 (cytoplasmic linker associated protein 1)	protein interactions	23332	108	2	19454	50	DCLK2,MACF1
3.147e-02	-3.46	EN1 (engrailed homeobox 1)	protein interactions	2019	108	2	19454	50	TRPS1,NFIA
3.147e-02	-3.46	FKBP1A (FKBP prolyl isomerase 1A)	protein interactions	2280	108	2	19454	50	RYR3,MSI2
3.147e-02	-3.46	DSG4 (desmoglein 4)	protein interactions	147409	108	2	19454	50	SPARCL1,CSGALNACT1
3.147e-02	-3.46	PAX8 (paired box 8)	protein interactions	7849	108	2	19454	50	NFIA,TRPS1
3.149e-02	-3.46	PFN1 (profilin 1)	protein interactions	5216	466	4	19454	50	FMN2,ABLIM1,MACF1,NHSL1
3.169e-02	-3.45	intracellular monoatomic ion homeostasis	biological process	GO:0006873	437	4	18204	50	SLC4A4,RYR3,SLC1A3,ATP13A4
3.190e-02	-3.45	MH1	pfam domains	PF03165	12	1	17795	48	NFIA
3.193e-02	-3.44	MAD_homology1_Dwarfin-type	interpro domains	IPR003619	12	1	18521	50	NFIA
3.193e-02	-3.44	TGFB_receptor	interpro domains	IPR000333	12	1	18521	50	BMPR1B
3.196e-02	-3.44	GABAergic synapse	KEGG pathways	hsa04727	88	2	7161	23	PRKCA,ADCY2
3.196e-02	-3.44	GABAergic synapse	KEGG pathways	ko04727	88	2	7161	23	ADCY2,PRKCA
3.200e-02	-3.44	MIR34B (microRNA 34b)	protein interactions	407041	109	2	19454	50	MSI2,QKI
3.200e-02	-3.44	PRR20A (proline rich 20A)	protein interactions	122183	109	2	19454	50	SOX5,TRPM3
3.200e-02	-3.44	CLSTN1 (calsyntenin 1)	protein interactions	22883	109	2	19454	50	SLC1A3,MGAT4C
3.204e-02	-3.44	human chr9q21.33	chromosome location	human chr9q21.33	17	1	26134	50	NTRK2
3.220e-02	-3.44	VEGFR2 mediated cell proliferation	REACTOME pathways	R-HSA-5218921	258	3	10285	28	NRG3,PRKCA,ITPR2
3.220e-02	-3.44	Defective EXT2 causes exostoses 2	REACTOME pathways	R-HSA-3656237	12	1	10285	28	GPC5
3.220e-02	-3.44	Defective EXT1 causes exostoses 1, TRPS2 and CHDS	REACTOME pathways	R-HSA-3656253	12	1	10285	28	GPC5
3.227e-02	-3.43	Stimuli-sensing channels	REACTOME pathways	R-HSA-2672351	104	2	10285	28	RYR3,TRPM3
3.248e-02	-3.43	positive regulation of extrinsic apoptotic signaling pathway via death domain receptors	biological process	GO:1902043	12	1	18204	50	BMPR1B
3.248e-02	-3.43	sulfur amino acid transport	biological process	GO:0000101	12	1	18204	50	SLC1A2
3.248e-02	-3.43	regulation of glial cell apoptotic process	biological process	GO:0034350	12	1	18204	50	PRKCA
3.248e-02	-3.43	nuclear membrane disassembly	biological process	GO:0051081	12	1	18204	50	PRKCA
3.248e-02	-3.43	microglia differentiation	biological process	GO:0014004	12	1	18204	50	QKI
3.248e-02	-3.43	auditory behavior	biological process	GO:0031223	12	1	18204	50	SLC1A3
3.248e-02	-3.43	mammalian oogenesis stage	biological process	GO:0022605	12	1	18204	50	BMPR1B
3.248e-02	-3.43	dermatan sulfate proteoglycan metabolic process	biological process	GO:0050655	12	1	18204	50	CSGALNACT1
3.250e-02	-3.43	DNA-binding transcription repressor activity, RNA polymerase II-specific	molecular function	GO:0001227	263	3	18094	48	GLIS3,TRPS1,ZBTB20
3.254e-02	-3.43	LZTR1 (leucine zipper like post translational regulator 1)	protein interactions	8216	110	2	19454	50	PARD3B,BMPR1B
3.271e-02	-3.42	RDX (radixin)	protein interactions	5962	272	3	19454	50	MACF1,ABLIM1,NEBL
3.287e-02	-3.42	breast-carcinoma-HER-positive_carcinoma	COSMIC cancer mutations	breast-carcinoma-HER-positive_carcinoma	2025	11	16828	50	RORA,NRG3,PPP2R2B,MSI2,MAML2,LIFR,PRKCA,GPC5,ABLIM1,BMPR1B,NTRK2
3.287e-02	-3.42	HER-positive_carcinoma	COSMIC cancer mutations	HER-positive_carcinoma	2025	11	16828	50	NRG3,RORA,MSI2,PPP2R2B,LIFR,PRKCA,MAML2,ABLIM1,GPC5,BMPR1B,NTRK2
3.291e-02	-3.41	PCDHA2 (protocadherin alpha 2)	protein interactions	56146	13	1	19454	50	NFIA
3.291e-02	-3.41	IL23R (interleukin 23 receptor)	protein interactions	149233	13	1	19454	50	PRKCA
3.291e-02	-3.41	JAM2 (junctional adhesion molecule 2)	protein interactions	58494	13	1	19454	50	PARD3
3.291e-02	-3.41	TBCC (tubulin folding cofactor C)	protein interactions	6903	13	1	19454	50	NTM
3.291e-02	-3.41	SPINK5 (serine peptidase inhibitor Kazal type 5)	protein interactions	11005	13	1	19454	50	CSGALNACT1
3.291e-02	-3.41	Rbm47 (RNA binding motif protein 47)	protein interactions	245945	13	1	19454	50	QKI
3.291e-02	-3.41	KCNQ2 (potassium voltage-gated channel subfamily Q member 2)	protein interactions	3785	13	1	19454	50	PRKCA
3.291e-02	-3.41	RAB3C (RAB3C, member RAS oncogene family)	protein interactions	115827	13	1	19454	50	GPM6A
3.300e-02	-3.41	dermatan sulfate biosynthesis	BIOCYC pathways	META_PWY-6571	15	1	902	2	CSGALNACT1
3.302e-02	-3.41	FLOT2 (flotillin 2)	protein interactions	2319	273	3	19454	50	PARD3,NTRK2,SOX5
3.315e-02	-3.41	MIP	prosite domains	PS00221	10	1	12186	41	AQP4
3.363e-02	-3.39	HMGCS1 (3-hydroxy-3-methylglutaryl-CoA synthase 1)	protein interactions	3157	112	2	19454	50	GPM6A,PPP2R2B
3.363e-02	-3.39	CEP170P1 (centrosomal protein 170 pseudogene 1)	protein interactions	645455	112	2	19454	50	TRPS1,MACF1
3.373e-02	-3.39	cellular response to alcohol	biological process	GO:0097306	105	2	18204	50	ADCY2,ITPR2
3.373e-02	-3.39	response to interleukin-1	biological process	GO:0070555	105	2	18204	50	PRKCA,RORA
3.377e-02	-3.39	FOLN	smart domains	SM00274	9	1	9717	37	SPARCL1
3.377e-02	-3.39	DCX	smart domains	SM00537	9	1	9717	37	DCLK2
3.381e-02	-3.39	positive regulation of developmental process	biological process	GO:0051094	1385	8	18204	50	SASH1,QKI,MACF1,PRKCA,SOX5,NTRK2,BMPR1B,PTPRZ1
3.389e-02	-3.38	human chr7q31.32	chromosome location	human chr7q31.32	18	1	26134	50	PTPRZ1
3.389e-02	-3.38	human chr18q21.33	chromosome location	human chr18q21.33	18	1	26134	50	CDH20
3.394e-02	-3.38	NAKATPASE	prints domains	PR00121	9	1	5227	20	ATP13A4
3.395e-02	-3.38	monoatomic cation:bicarbonate symporter activity	molecular function	GO:0140410	13	1	18094	48	SLC4A4
3.395e-02	-3.38	transforming growth factor beta receptor activity	molecular function	GO:0005024	13	1	18094	48	BMPR1B
3.399e-02	-3.38	Morphine addiction	KEGG pathways	hsa05032	91	2	7161	23	ADCY2,PRKCA
3.399e-02	-3.38	mRNA surveillance pathway	KEGG pathways	hsa03015	91	2	7161	23	PPP2R2B,MSI2
3.399e-02	-3.38	Morphine addiction	KEGG pathways	ko05032	91	2	7161	23	PRKCA,ADCY2
3.399e-02	-3.38	mRNA surveillance pathway	KEGG pathways	ko03015	91	2	7161	23	MSI2,PPP2R2B
3.408e-02	-3.38	organic anion transmembrane transporter activity	molecular function	GO:0008514	268	3	18094	48	SLC4A4,SLC1A3,SLC1A2
3.413e-02	-3.38	Ras signaling in the CD4+ TCR pathway	Pathway Interaction DB	tcrraspathway	11	1	2226	7	PRKCA
3.425e-02	-3.37	ACIN1 (apoptotic chromatin condensation inducer 1)	protein interactions	22985	277	3	19454	50	CSGALNACT1,NFIA,PRKCA
3.425e-02	-3.37	ZDHHC17 (zinc finger DHHC-type palmitoyltransferase 17)	protein interactions	23390	277	3	19454	50	SLC1A3,NEBL,GPM6A
3.432e-02	-3.37	oogenesis	biological process	GO:0048477	106	2	18204	50	BMPR1B,FMN2
3.440e-02	-3.37	DNA-binding transcription factor activity	molecular function	GO:0003700	1441	8	18094	48	RFX4,ZBTB20,GLIS3,NPAS3,TRPS1,SOX5,RORA,NFIA
3.457e-02	-3.36	TJP2 (tight junction protein 2)	protein interactions	9414	278	3	19454	50	SORBS1,NEBL,PARD3
3.474e-02	-3.36	ORF3b (ORF3b protein)	protein interactions	1489670	114	2	19454	50	MACF1,ZBTB20
3.484e-02	-3.36	Passive transport by Aquaporins	REACTOME pathways	R-HSA-432047	13	1	10285	28	AQP4
3.484e-02	-3.36	CLEC7A (Dectin-1) induces NFAT activation	REACTOME pathways	R-HSA-5607763	13	1	10285	28	ITPR2
3.484e-02	-3.36	ERBB2 Activates PTK6 Signaling	REACTOME pathways	R-HSA-8847993	13	1	10285	28	NRG3
3.484e-02	-3.36	Notch-HLH transcription pathway	REACTOME pathways	R-HSA-350054	13	1	10285	28	MAML2
3.484e-02	-3.36	NOTCH2 intracellular domain regulates transcription	REACTOME pathways	R-HSA-2197563	13	1	10285	28	MAML2
3.496e-02	-3.35	response to organic substance	biological process	GO:0010033	2498	12	18204	50	NTRK2,RORA,SLC1A2,PRKCA,ADCY2,RYR3,ITPR2,LIFR,AQP4,SLC1A3,SORBS1,ZBTB20
3.496e-02	-3.35	large_intestine-rectum-adenoma	COSMIC cancer mutations	large_intestine-rectum-adenoma	99	2	16828	50	NTRK2,LIFR
3.505e-02	-3.35	cellular response to stimulus	biological process	GO:0051716	6307	24	18204	50	ITPR2,FMN2,RORA,NTRK2,SLC1A2,RYR3,CTNND2,PARD3,MACF1,NFIA,ZBTB20,DCLK2,LIFR,PRKCA,ADCY2,BMPR1B,DTNA,NRG3,MAML2,SLC1A3,SORBS1,PITPNC1,AQP4,SPARCL1
3.509e-02	-3.35	central_nervous_system-fourth_ventricle-glioma-astrocytoma_Grade_I	COSMIC cancer mutations	central_nervous_system-fourth_ventricle-glioma-astrocytoma_Grade_I	12	1	16828	50	QKI
3.514e-02	-3.35	ectodermal placode development	biological process	GO:0071696	13	1	18204	50	NRG3
3.514e-02	-3.35	T-helper 17 cell differentiation	biological process	GO:0072539	13	1	18204	50	RORA
3.514e-02	-3.35	membrane disassembly	biological process	GO:0030397	13	1	18204	50	PRKCA
3.514e-02	-3.35	cerebellar Purkinje cell differentiation	biological process	GO:0021702	13	1	18204	50	RORA
3.514e-02	-3.35	glial cell fate commitment	biological process	GO:0021781	13	1	18204	50	NFIA
3.518e-02	-3.35	chondroitin sulfate biosynthesis	BIOCYC pathways	HUMAN_PWY-6569	16	1	902	2	CSGALNACT1
3.530e-02	-3.34	DTNA (dystrobrevin alpha)	protein interactions	1837	115	2	19454	50	NTRK2,PARD3
3.530e-02	-3.34	CDH2 (cadherin 2)	protein interactions	1000	115	2	19454	50	CTNND2,PARD3
3.530e-02	-3.34	TBXT (T-box transcription factor T)	protein interactions	6862	115	2	19454	50	TRPS1,NFIA
3.533e-02	-3.34	EF_HAND_2	prosite domains	PS50222	215	3	12186	41	RYR3,MACF1,SPARCL1
3.538e-02	-3.34	DNA-binding transcription repressor activity	molecular function	GO:0001217	272	3	18094	48	ZBTB20,TRPS1,GLIS3
3.540e-02	-3.34	TAS2R7 (taste 2 receptor member 7)	protein interactions	50837	14	1	19454	50	PRKCA
3.540e-02	-3.34	CHAT (choline O-acetyltransferase)	protein interactions	1103	14	1	19454	50	PRKCA
3.540e-02	-3.34	BOD1L2 (biorientation of chromosomes in cell division 1 like 2)	protein interactions	284257	14	1	19454	50	FMN2
3.540e-02	-3.34	SLC1A2 (solute carrier family 1 member 2)	protein interactions	6506	14	1	19454	50	SLC1A2
3.540e-02	-3.34	PLXNA4 (plexin A4)	protein interactions	91584	14	1	19454	50	GPM6A
3.540e-02	-3.34	DACT2 (dishevelled binding antagonist of beta catenin 2)	protein interactions	168002	14	1	19454	50	ZBTB20
3.540e-02	-3.34	MB (myoglobin)	protein interactions	4151	14	1	19454	50	MAML2
3.540e-02	-3.34	SPRR2D (small proline rich protein 2D)	protein interactions	6703	14	1	19454	50	PPP2R2B
3.540e-02	-3.34	Nedd4 (neural precursor cell expressed, developmentally down-regulated 4)	protein interactions	17999	14	1	19454	50	GLIS3
3.540e-02	-3.34	FCGBP (Fc gamma binding protein)	protein interactions	8857	14	1	19454	50	PPP2R2B
3.540e-02	-3.34	RHEBL1 (RHEB like 1)	protein interactions	121268	14	1	19454	50	BMPR1B
3.540e-02	-3.34	JMJD7-PLA2G4B (JMJD7-PLA2G4B readthrough)	protein interactions	8681	14	1	19454	50	PPP2R2B
3.540e-02	-3.34	Asap1 (ArfGAP with SH3 domain, ankyrin repeat and PH domain1)	protein interactions	13196	14	1	19454	50	MACF1
3.569e-02	-3.33	DYNLL1 (dynein light chain LC8-type 1)	protein interactions	8655	485	4	19454	50	NTRK2,PARD3,PPP2R2B,TRPS1
3.574e-02	-3.33	human chr11q25	chromosome location	human chr11q25	19	1	26134	50	NTM
3.574e-02	-3.33	human chr5p15.2	chromosome location	human chr5p15.2	19	1	26134	50	CTNND2
3.574e-02	-3.33	human chr6q24.1	chromosome location	human chr6q24.1	19	1	26134	50	NHSL1
3.602e-02	-3.32	kidney-carcinoma	COSMIC cancer mutations	kidney-carcinoma	3720	17	16828	50	FBXL7,SOX5,RORA,PITPNC1,LIFR,TRPS1,CTNND2,BMPR1B,QKI,NTRK2,PTPRZ1,MSI2,PPP2R2B,PRKCA,MAML2,ITPR2,DCLK2
3.610e-02	-3.32	pleura	COSMIC cancer mutations	pleura	4914	21	16828	50	NTM,CTNND2,TRPS1,LIFR,PITPNC1,NEBL,RORA,SOX5,ATP13A4,FBXL7,ITPR2,DCLK2,PRKCA,MAML2,MSI2,FMN2,PPP2R2B,PTPRZ1,NTRK2,BMPR1B,QKI
3.630e-02	-3.32	positive regulation of biological process	biological process	GO:0048518	6326	24	18204	50	SLC1A2,RORA,NTRK2,PTPRZ1,FMN2,LIFR,PARD3,NPAS3,SASH1,GLIS3,NFIA,ZBTB20,MACF1,BMPR1B,PRKCA,GPC5,GPM6A,SLC4A4,RFX4,SOX5,MAML2,SORBS1,QKI,SLC1A3
3.631e-02	-3.32	neuronal cell body	cellular component	GO:0043025	489	4	19108	49	BMPR1B,GPM6A,SLC1A3,CTNND2
3.641e-02	-3.31	GATA_ZN_FINGER_2	prosite domains	PS50114	11	1	12186	41	TRPS1
3.641e-02	-3.31	RECEPTOR_TYR_KIN_II	prosite domains	PS00239	11	1	12186	41	NTRK2
3.642e-02	-3.31	ELK3 (ETS transcription factor ELK3)	protein interactions	2004	117	2	19454	50	TRPS1,NFIA
3.652e-02	-3.31	microtubule minus-end binding	molecular function	GO:0051011	14	1	18094	48	MACF1
3.668e-02	-3.31	CAV1 (caveolin 1)	protein interactions	857	719	5	19454	50	MACF1,FMN2,PARD3,SLC1A3,DTNA
3.680e-02	-3.30	PPARG (peroxisome proliferator activated receptor gamma)	protein interactions	5468	285	3	19454	50	ZBTB20,TRPS1,PRKCA
3.688e-02	-3.30	plasma membrane bounded cell projection organization	biological process	GO:0120036	1152	7	18204	50	PARD3,ABLIM1,GPM6A,BMPR1B,RFX4,PTPRZ1,CTNND2
3.695e-02	-3.30	synaptic signaling	biological process	GO:0099536	459	4	18204	50	SLC1A3,DTNA,NTRK2,SLC1A2
3.699e-02	-3.30	DNM1 (dynamin 1)	protein interactions	1759	118	2	19454	50	GPM6A,PRKCA
3.699e-02	-3.30	VSIG8 (V-set and immunoglobulin domain containing 8)	protein interactions	391123	118	2	19454	50	SPARCL1,CSGALNACT1
3.709e-02	-3.29	ear	COSMIC cancer mutations	ear	624	5	16828	50	LIFR,NPAS3,ZBTB20,SPARCL1,MGAT4C
3.712e-02	-3.29	MIP	pfam domains	PF00230	14	1	17795	48	AQP4
3.712e-02	-3.29	GATA	pfam domains	PF00320	14	1	17795	48	TRPS1
3.714e-02	-3.29	PROTEIN_KINASE_ATP	prosite domains	PS00107	377	4	12186	41	DCLK2,BMPR1B,NTRK2,PRKCA
3.715e-02	-3.29	Aquaporin-like	interpro domains	IPR023271	14	1	18521	50	AQP4
3.715e-02	-3.29	MIP	interpro domains	IPR000425	14	1	18521	50	AQP4
3.747e-02	-3.28	SHC1 events in ERBB4 signaling	REACTOME pathways	R-HSA-1250347	14	1	10285	28	NRG3
3.747e-02	-3.28	DCC mediated attractive signaling	REACTOME pathways	R-HSA-418885	14	1	10285	28	ABLIM1
3.754e-02	-3.28	basal plasma membrane	cellular component	GO:0009925	288	3	19108	49	AQP4,SLC4A4,SLC1A3
3.756e-02	-3.28	RBM7 (RNA binding motif protein 7)	protein interactions	10179	119	2	19454	50	QKI,PPP2R2B
3.756e-02	-3.28	ANKRD26 (ankyrin repeat domain containing 26)	protein interactions	22852	119	2	19454	50	NTRK2,PARD3
3.764e-02	-3.28	HCO3TRNSPORT	prints domains	PR01231	10	1	5227	20	SLC4A4
3.779e-02	-3.28	glutathione biosynthetic process	biological process	GO:0006750	14	1	18204	50	SLC1A2
3.779e-02	-3.28	cellular response to ethanol	biological process	GO:0071361	14	1	18204	50	ITPR2
3.779e-02	-3.28	regulation of protein K63-linked ubiquitination	biological process	GO:1900044	14	1	18204	50	SASH1
3.779e-02	-3.28	cellular response to forskolin	biological process	GO:1904322	14	1	18204	50	ADCY2
3.779e-02	-3.28	response to forskolin	biological process	GO:1904321	14	1	18204	50	ADCY2
3.779e-02	-3.28	mechanosensory behavior	biological process	GO:0007638	14	1	18204	50	SLC1A3
3.779e-02	-3.28	sodium ion export across plasma membrane	biological process	GO:0036376	14	1	18204	50	SLC4A4
3.779e-02	-3.28	cellular response to purine-containing compound	biological process	GO:0071415	14	1	18204	50	RYR3
3.779e-02	-3.28	cerebrospinal fluid circulation	biological process	GO:0090660	14	1	18204	50	AQP4
3.780e-02	-3.28	axolemma	cellular component	GO:0030673	15	1	19108	49	SLC1A2
3.788e-02	-3.27	ENTPD5 (ectonucleoside triphosphate diphosphohydrolase 5 (inactive))	protein interactions	957	15	1	19454	50	PRKCA
3.788e-02	-3.27	XIRP1 (xin actin binding repeat containing 1)	protein interactions	165904	15	1	19454	50	NEBL
3.788e-02	-3.27	OGG1 (8-oxoguanine DNA glycosylase)	protein interactions	4968	15	1	19454	50	PRKCA
3.788e-02	-3.27	PCSK1N (proprotein convertase subtilisin/kexin type 1 inhibitor)	protein interactions	27344	15	1	19454	50	MGAT4C
3.788e-02	-3.27	TAFA5 (TAFA chemokine like family member 5)	protein interactions	25817	15	1	19454	50	NEBL
3.788e-02	-3.27	FN3K (fructosamine 3 kinase)	protein interactions	64122	15	1	19454	50	PRKCA
3.788e-02	-3.27	ADRA1B (adrenoceptor alpha 1B)	protein interactions	147	15	1	19454	50	PRKCA
3.788e-02	-3.27	TIAM2 (TIAM Rac1 associated GEF 2)	protein interactions	26230	15	1	19454	50	PARD3
3.788e-02	-3.27	TESPA1 (thymocyte expressed, positive selection associated 1)	protein interactions	9840	15	1	19454	50	ITPR2
3.788e-02	-3.27	GRM7 (glutamate metabotropic receptor 7)	protein interactions	2917	15	1	19454	50	PRKCA
3.788e-02	-3.27	IGSF1 (immunoglobulin superfamily member 1)	protein interactions	3547	15	1	19454	50	BMPR1B
3.794e-02	-3.27	rhythmic process	biological process	GO:0048511	270	3	18204	50	RORA,NTRK2,BMPR1B
3.794e-02	-3.27	regulation of gliogenesis	biological process	GO:0014013	112	2	18204	50	QKI,PTPRZ1
3.796e-02	-3.27	central_nervous_system-hypothalamus-glioma-astrocytoma_Grade_I	COSMIC cancer mutations	central_nervous_system-hypothalamus-glioma-astrocytoma_Grade_I	13	1	16828	50	QKI
3.807e-02	-3.27	small_intestine	COSMIC cancer mutations	small_intestine	250	3	16828	50	MACF1,MGAT4C,CSGALNACT1
3.810e-02	-3.27	CEP128 (centrosomal protein 128)	protein interactions	145508	289	3	19454	50	SORBS1,NEBL,ABLIM1
3.819e-02	-3.27	membrane raft	cellular component	GO:0045121	290	3	19108	49	SLC1A2,ADCY2,SORBS1
3.820e-02	-3.26	Phosphatidylinositol signaling system	KEGG pathways	hsa04070	97	2	7161	23	PRKCA,ITPR2
3.820e-02	-3.26	Phosphatidylinositol signaling system	KEGG pathways	ko04070	97	2	7161	23	PRKCA,ITPR2
3.840e-02	-3.26	KIF14 (kinesin family member 14)	protein interactions	9928	1803	9	19454	50	SOX5,ITPR2,MSI2,NEBL,SORBS1,PARD3,SLC1A3,MACF1,ABLIM1
3.849e-02	-3.26	chromophobe_renal_cell_carcinoma	COSMIC cancer mutations	chromophobe_renal_cell_carcinoma	430	4	16828	50	DCLK2,NTRK2,PRKCA,BMPR1B
3.849e-02	-3.26	kidney-carcinoma-chromophobe_renal_cell_carcinoma	COSMIC cancer mutations	kidney-carcinoma-chromophobe_renal_cell_carcinoma	430	4	16828	50	BMPR1B,NTRK2,PRKCA,DCLK2
3.872e-02	-3.25	MED15 (mediator complex subunit 15)	protein interactions	51586	121	2	19454	50	NFIA,QKI
3.885e-02	-3.25	membrane microdomain	cellular component	GO:0098857	292	3	19108	49	SORBS1,SLC1A2,ADCY2
3.892e-02	-3.25	Estrogen signaling pathway	KEGG pathways	hsa04915	98	2	7161	23	ADCY2,ITPR2
3.892e-02	-3.25	Estrogen signaling pathway	KEGG pathways	ko04915	98	2	7161	23	ADCY2,ITPR2
3.896e-02	-3.25	lung-carcinoma-large_cell_carcinoma	COSMIC cancer mutations	lung-carcinoma-large_cell_carcinoma	849	6	16828	50	BMPR1B,PTPRZ1,NTRK2,DCLK2,PRKCA,LIFR
3.896e-02	-3.25	large_cell_carcinoma	COSMIC cancer mutations	large_cell_carcinoma	849	6	16828	50	DCLK2,PTPRZ1,LIFR,PRKCA,NTRK2,BMPR1B
3.900e-02	-3.24	vascular process in circulatory system	biological process	GO:0003018	273	3	18204	50	SLC4A4,SLC1A2,SLC1A3
3.908e-02	-3.24	phosphatidylglycerol binding	molecular function	GO:1901611	15	1	18094	48	PITPNC1
3.908e-02	-3.24	tropomyosin binding	molecular function	GO:0005523	15	1	18094	48	NEBL
3.908e-02	-3.24	filamin binding	molecular function	GO:0031005	15	1	18094	48	NEBL
3.910e-02	-3.24	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-acute_lymphoblastic_leukaemia	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-acute_lymphoblastic_leukaemia	2081	11	16828	50	ADCY2,DCLK2,DTNA,SLC4A4,PRKCA,BMPR1B,PTPRZ1,NTRK2,TRPS1,NFIA,SOX5
3.930e-02	-3.24	BRK1 (BRICK1 subunit of SCAR/WAVE actin nucleating complex)	protein interactions	55845	122	2	19454	50	DTNA,NHSL1
3.934e-02	-3.24	SH3DOMAIN	prints domains	PR00452	83	2	5227	20	SORBS1,NEBL
3.943e-02	-3.23	human chr13q31.3	chromosome location	human chr13q31.3	21	1	26134	50	GPC5
3.943e-02	-3.23	human chr10q23.1	chromosome location	human chr10q23.1	21	1	26134	50	NRG3
3.943e-02	-3.23	cell migration	biological process	GO:0016477	921	6	18204	50	CDH20,NTRK2,GPM6A,GPC5,FMN2,NRG3
3.953e-02	-3.23	chondroitin sulfate biosynthesis	BIOCYC pathways	META_PWY-6569	18	1	902	2	CSGALNACT1
3.972e-02	-3.23	FH2	pfam domains	PF02181	15	1	17795	48	FMN2
3.975e-02	-3.23	Znf_GATA	interpro domains	IPR000679	15	1	18521	50	TRPS1
3.975e-02	-3.23	FH2_Formin	interpro domains	IPR015425	15	1	18521	50	FMN2
3.975e-02	-3.23	FH2_Formin_sf	interpro domains	IPR042201	15	1	18521	50	FMN2
3.988e-02	-3.22	PAX7 (paired box 7)	protein interactions	5081	123	2	19454	50	TRPS1,NFIA
4.008e-02	-3.22	transcription cis-regulatory region binding	molecular function	GO:0000976	1485	8	18094	48	SOX5,GLIS3,NPAS3,TRPS1,ZBTB20,RFX4,NFIA,RORA
4.009e-02	-3.22	ERBB2 Regulates Cell Motility	REACTOME pathways	R-HSA-6785631	15	1	10285	28	NRG3
4.009e-02	-3.22	Adenylate cyclase inhibitory pathway	REACTOME pathways	R-HSA-170670	15	1	10285	28	ADCY2
4.009e-02	-3.22	Inhibition of adenylate cyclase pathway	REACTOME pathways	R-HSA-997269	15	1	10285	28	ADCY2
4.009e-02	-3.22	N-Glycan antennae elongation	REACTOME pathways	R-HSA-975577	15	1	10285	28	MGAT4C
4.009e-02	-3.22	Depolymerisation of the Nuclear Lamina	REACTOME pathways	R-HSA-4419969	15	1	10285	28	PRKCA
4.009e-02	-3.22	WNT5A-dependent internalization of FZD4	REACTOME pathways	R-HSA-5099900	15	1	10285	28	PRKCA
4.022e-02	-3.21	ErbB receptor signaling network	Pathway Interaction DB	erbb_network_pathway	13	1	2226	7	NRG3
4.023e-02	-3.21	Prot_kinase_dom	interpro domains	IPR000719	480	4	18521	50	NTRK2,PRKCA,DCLK2,BMPR1B
4.024e-02	-3.21	animal organ development	biological process	GO:0048513	2846	13	18204	50	NFIA,DCLK2,SOX5,RFX4,ABLIM1,GPM6A,NRG3,BMPR1B,NEBL,RORA,CSGALNACT1,NTRK2,SLC1A2
4.026e-02	-3.21	bone-humerus-Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour	COSMIC cancer mutations	bone-humerus-Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour	107	2	16828	50	PARD3B,NEBL
4.028e-02	-3.21	phospholipid binding	molecular function	GO:0005543	489	4	18094	48	PITPNC1,ITPR2,PARD3,PARD3B
4.035e-02	-3.21	transcription regulatory region nucleic acid binding	molecular function	GO:0001067	1487	8	18094	48	RFX4,ZBTB20,SOX5,GLIS3,TRPS1,NPAS3,NFIA,RORA
4.035e-02	-3.21	WWC3 (WWC family member 3)	protein interactions	55841	16	1	19454	50	PRKCA
4.035e-02	-3.21	AMMECR1L (AMMECR1 like)	protein interactions	83607	16	1	19454	50	MACF1
4.035e-02	-3.21	Sumo3 (small ubiquitin-like modifier 3)	protein interactions	20610	16	1	19454	50	ITPR2
4.035e-02	-3.21	CNTFR (ciliary neurotrophic factor receptor)	protein interactions	1271	16	1	19454	50	LIFR
4.035e-02	-3.21	SLC6A9 (solute carrier family 6 member 9)	protein interactions	6536	16	1	19454	50	PRKCA
4.035e-02	-3.21	NRGN (neurogranin)	protein interactions	4900	16	1	19454	50	PRKCA
4.035e-02	-3.21	GABRR1 (gamma-aminobutyric acid type A receptor subunit rho1)	protein interactions	2569	16	1	19454	50	PRKCA
4.035e-02	-3.21	RHO (rhodopsin)	protein interactions	6010	16	1	19454	50	PRKCA
4.035e-02	-3.21	TWIST2 (twist family bHLH transcription factor 2)	protein interactions	117581	16	1	19454	50	ZBTB20
4.035e-02	-3.21	GABRB3 (gamma-aminobutyric acid type A receptor subunit beta3)	protein interactions	2562	16	1	19454	50	PRKCA
4.035e-02	-3.21	FNDC8 (fibronectin type III domain containing 8)	protein interactions	54752	16	1	19454	50	SPARCL1
4.035e-02	-3.21	ORM2 (orosomucoid 2)	protein interactions	5005	16	1	19454	50	PPP2R2B
4.035e-02	-3.21	CNTNAP2 (contactin associated protein 2)	protein interactions	26047	16	1	19454	50	MACF1
4.043e-02	-3.21	exit from mitosis	biological process	GO:0010458	15	1	18204	50	NFIA
4.043e-02	-3.21	cerebellar Purkinje cell layer formation	biological process	GO:0021694	15	1	18204	50	RORA
4.043e-02	-3.21	neuroblast division	biological process	GO:0055057	15	1	18204	50	SOX5
4.043e-02	-3.21	regulation of neuron projection arborization	biological process	GO:0150011	15	1	18204	50	MACF1
4.043e-02	-3.21	peripheral nervous system neuron development	biological process	GO:0048935	15	1	18204	50	NTRK2
4.043e-02	-3.21	response to caffeine	biological process	GO:0031000	15	1	18204	50	RYR3
4.043e-02	-3.21	synapse maturation	biological process	GO:0060074	15	1	18204	50	NFIA
4.043e-02	-3.21	positive regulation of glycogen biosynthetic process	biological process	GO:0045725	15	1	18204	50	SORBS1
4.043e-02	-3.21	sarcoplasmic reticulum calcium ion transport	biological process	GO:0070296	15	1	18204	50	RYR3
4.043e-02	-3.21	pyramidal neuron differentiation	biological process	GO:0021859	15	1	18204	50	DCLK2
4.043e-02	-3.21	protein homotrimerization	biological process	GO:0070207	15	1	18204	50	SLC1A2
4.043e-02	-3.21	peripheral nervous system neuron differentiation	biological process	GO:0048934	15	1	18204	50	NTRK2
4.047e-02	-3.21	PSME2 (proteasome activator subunit 2)	protein interactions	5721	124	2	19454	50	PARD3,PPP2R2B
4.065e-02	-3.20	membrane protein complex	cellular component	GO:0098796	1261	7	19108	49	RYR3,CDH20,SLC1A2,BMPR1B,SLC1A3,PRKCA,SORBS1
4.079e-02	-3.20	TJP1 (tight junction protein 1)	protein interactions	7082	297	3	19454	50	PARD3,DTNA,NEBL
4.080e-02	-3.20	actin filament organization	biological process	GO:0007015	278	3	18204	50	NEBL,SORBS1,FMN2
4.083e-02	-3.20	neuron projection development	biological process	GO:0031175	693	5	18204	50	CTNND2,GPM6A,PTPRZ1,BMPR1B,PARD3
4.083e-02	-3.20	Glycerol uptake facilitator protein	gene3d domains	1.20.1080.10	14	1	14470	43	AQP4
4.099e-02	-3.19	SH3	smart domains	SM00326	202	3	9717	37	NEBL,SASH1,SORBS1
4.106e-02	-3.19	STXBP1 (syntaxin binding protein 1)	protein interactions	6812	125	2	19454	50	GPM6A,PRKCA
4.111e-02	-3.19	Melanogenesis	KEGG pathways	ko04916	101	2	7161	23	PRKCA,ADCY2
4.111e-02	-3.19	Melanogenesis	KEGG pathways	hsa04916	101	2	7161	23	ADCY2,PRKCA
4.117e-02	-3.19	secondary active transmembrane transporter activity	molecular function	GO:0015291	289	3	18094	48	SLC1A2,SLC4A4,SLC1A3
4.148e-02	-3.18	bicellular tight junction	cellular component	GO:0005923	126	2	19108	49	PARD3B,PARD3
4.154e-02	-3.18	glycoprotein biosynthetic process	biological process	GO:0009101	280	3	18204	50	BMPR1B,MGAT4C,CSGALNACT1
4.163e-02	-3.18	adenylate cyclase activity	molecular function	GO:0004016	16	1	18094	48	ADCY2
4.163e-02	-3.18	mitogen-activated protein kinase kinase kinase binding	molecular function	GO:0031435	16	1	18094	48	SASH1
4.163e-02	-3.18	oxysterol binding	molecular function	GO:0008142	16	1	18094	48	RORA
4.163e-02	-3.18	diacylglycerol-dependent serine/threonine kinase activity	molecular function	GO:0004697	16	1	18094	48	PRKCA
4.163e-02	-3.18	water channel activity	molecular function	GO:0015250	16	1	18094	48	AQP4
4.166e-02	-3.18	SYP (synaptophysin)	protein interactions	6855	126	2	19454	50	GPM6A,PITPNC1
4.170e-02	-3.18	synapse assembly	biological process	GO:0007416	118	2	18204	50	NRG3,GPM6A
4.186e-02	-3.17	Glucagon signaling pathway	KEGG pathways	hsa04922	102	2	7161	23	ITPR2,ADCY2
4.186e-02	-3.17	Glucagon signaling pathway	KEGG pathways	ko04922	102	2	7161	23	ITPR2,ADCY2
4.212e-02	-3.17	SLC-mediated transmembrane transport	REACTOME pathways	R-HSA-425407	287	3	10285	28	SLC1A3,SLC4A4,SLC1A2
4.231e-02	-3.16	ductal_carcinoma	COSMIC cancer mutations	ductal_carcinoma	15798	50	16828	50	CSGALNACT1,QKI,CDH20,RFX4,MSI2,NEBL,NRG3,TRPS1,BMPR1B,LSAMP,PPP2R2B,DCLK2,PRKCA,ATP13A4,SASH1,NPAS3,CTNND2,GPC5,PARD3,FMN2,ADCY2,SLC1A3,ITPR2,ZBTB20,GLIS3,SLC4A4,SORBS1,MGAT4C,FBXL7,GPM6A,SOX5,PARD3B,RYR3,PITPNC1,RORA,LIFR,SLC1A2,PTPRZ1,NTRK2,DTNA,MAML2,TRPM3,SPARCL1,NKAIN3,NFIA,AQP4,NHSL1,ABLIM1,NTM,MACF1
4.247e-02	-3.16	germ_cell_tumour	COSMIC cancer mutations	germ_cell_tumour	867	6	16828	50	DCLK2,TRPS1,MACF1,NTRK2,PRKCA,BMPR1B
4.253e-02	-3.16	testis-germ_cell_tumour-seminoma	COSMIC cancer mutations	testis-germ_cell_tumour-seminoma	648	5	16828	50	TRPS1,DCLK2,NTRK2,PRKCA,BMPR1B
4.253e-02	-3.16	pulmonary_blastoma	COSMIC cancer mutations	pulmonary_blastoma	648	5	16828	50	BMPR1B,NEBL,TRPS1,ATP13A4,NTM
4.253e-02	-3.16	pleura-pulmonary_blastoma	COSMIC cancer mutations	pleura-pulmonary_blastoma	648	5	16828	50	ATP13A4,NTM,TRPS1,BMPR1B,NEBL
4.267e-02	-3.15	neuron projection terminus	cellular component	GO:0044306	128	2	19108	49	SLC1A2,NTRK2
4.271e-02	-3.15	GRB2 events in ERBB2 signaling	REACTOME pathways	R-HSA-1963640	16	1	10285	28	NRG3
4.271e-02	-3.15	Regulation of KIT signaling	REACTOME pathways	R-HSA-1433559	16	1	10285	28	PRKCA
4.271e-02	-3.15	PI3K events in ERBB2 signaling	REACTOME pathways	R-HSA-1963642	16	1	10285	28	NRG3
4.271e-02	-3.15	PKA activation	REACTOME pathways	R-HSA-163615	16	1	10285	28	ADCY2
4.282e-02	-3.15	Pef1 (penta-EF hand domain containing 1)	protein interactions	67898	17	1	19454	50	QKI
4.282e-02	-3.15	PAX4 (paired box 4)	protein interactions	5078	17	1	19454	50	NTM
4.282e-02	-3.15	TAGAP (T cell activation RhoGTPase activating protein)	protein interactions	117289	17	1	19454	50	DTNA
4.282e-02	-3.15	NOTCH4 (notch receptor 4)	protein interactions	4855	17	1	19454	50	MAML2
4.282e-02	-3.15	Sqstm1 (sequestosome 1)	protein interactions	18412	17	1	19454	50	BMPR1B
4.282e-02	-3.15	SEPSECS (Sep (O-phosphoserine) tRNA:Sec (selenocysteine) tRNA synthase)	protein interactions	51091	17	1	19454	50	ABLIM1
4.282e-02	-3.15	TNNT2 (troponin T2, cardiac type)	protein interactions	7139	17	1	19454	50	PRKCA
4.282e-02	-3.15	CYP3A4 (cytochrome P450 family 3 subfamily A member 4)	protein interactions	1576	17	1	19454	50	PRKCA
4.282e-02	-3.15	MSANTD2 (Myb/SANT DNA binding domain containing 2)	protein interactions	79684	17	1	19454	50	SOX5
4.282e-02	-3.15	RASL12 (RAS like family 12)	protein interactions	51285	17	1	19454	50	BMPR1B
4.282e-02	-3.15	PDE7A (phosphodiesterase 7A)	protein interactions	5150	17	1	19454	50	PRKCA
4.282e-02	-3.15	DPP6 (dipeptidyl peptidase like 6)	protein interactions	1804	17	1	19454	50	GPM6A
4.282e-02	-3.15	Shcbp1 (Shc SH2-domain binding protein 1)	protein interactions	20419	17	1	19454	50	GPC5
4.282e-02	-3.15	LIPT1 (lipoyltransferase 1)	protein interactions	51601	17	1	19454	50	PRKCA
4.285e-02	-3.15	PDZ	pfam domains	PF00595	122	2	17795	48	PARD3,PARD3B
4.286e-02	-3.15	ATF7IP (activating transcription factor 7 interacting protein)	protein interactions	55729	128	2	19454	50	MACF1,SOX5
4.286e-02	-3.15	MYB (MYB proto-oncogene, transcription factor)	protein interactions	4602	128	2	19454	50	TRPS1,NFIA
4.286e-02	-3.15	TEAD2 (TEA domain transcription factor 2)	protein interactions	8463	128	2	19454	50	TRPS1,ZBTB20
4.286e-02	-3.15	PRKAR2B (protein kinase cAMP-dependent type II regulatory subunit beta)	protein interactions	5577	128	2	19454	50	PRKCA,GPM6A
4.299e-02	-3.15	striated muscle contraction	biological process	GO:0006941	120	2	18204	50	RYR3,DTNA
4.307e-02	-3.14	nonribosomal peptide biosynthetic process	biological process	GO:0019184	16	1	18204	50	SLC1A2
4.307e-02	-3.14	positive regulation of macrophage differentiation	biological process	GO:0045651	16	1	18204	50	PRKCA
4.307e-02	-3.14	non-proteinogenic amino acid biosynthetic process	biological process	GO:0170043	16	1	18204	50	SLC1A3
4.311e-02	-3.14	human chr5p15.31	chromosome location	human chr5p15.31	23	1	26134	50	ADCY2
4.314e-02	-3.14	oesophagus-lower_third-carcinoma-squamous_cell_carcinoma	COSMIC cancer mutations	oesophagus-lower_third-carcinoma-squamous_cell_carcinoma	3507	16	16828	50	PARD3,PTPRZ1,ADCY2,FMN2,DCLK2,ZBTB20,SLC4A4,TRPM3,RYR3,PARD3B,SASH1,CTNND2,GPC5,NPAS3,MACF1,LIFR
4.319e-02	-3.14	oligoastrocytoma_Grade_III	COSMIC cancer mutations	oligoastrocytoma_Grade_III	263	3	16828	50	SOX5,SLC1A2,RYR3
4.321e-02	-3.14	CARM1 (coactivator associated arginine methyltransferase 1)	protein interactions	10498	304	3	19454	50	RORA,QKI,DTNA
4.322e-02	-3.14	Cadmium Induces DNA Synthesis and Proliferation in Macrophages	SMPDB pathways	SMP0063805	20	1	1369	3	PRKCA
4.346e-02	-3.14	CHD7 (chromodomain helicase DNA binding protein 7)	protein interactions	55636	129	2	19454	50	ZBTB20,SOX5
4.350e-02	-3.14	skin-scalp-carcinoma-squamous_cell_carcinoma	COSMIC cancer mutations	skin-scalp-carcinoma-squamous_cell_carcinoma	1596	9	16828	50	PTPRZ1,ATP13A4,SOX5,SLC4A4,MACF1,TRPS1,GPC5,RORA,LSAMP
4.360e-02	-3.13	skin-acral-malignant_melanoma	COSMIC cancer mutations	skin-acral-malignant_melanoma	264	3	16828	50	FMN2,PARD3,CDH20
4.367e-02	-3.13	hypothalamus	COSMIC cancer mutations	hypothalamus	15	1	16828	50	QKI
4.368e-02	-3.13	Formin, FH2 domain	gene3d domains	1.20.58.2220	15	1	14470	43	FMN2
4.388e-02	-3.13	Z disc	cellular component	GO:0030018	130	2	19108	49	NEBL,RYR3
4.400e-02	-3.12	basal part of cell	cellular component	GO:0045178	307	3	19108	49	AQP4,SLC4A4,SLC1A3
4.407e-02	-3.12	PKP1 (plakophilin 1)	protein interactions	5317	130	2	19454	50	CSGALNACT1,PPP2R2B
4.417e-02	-3.12	transmembrane receptor protein tyrosine phosphatase activity	molecular function	GO:0005001	17	1	18094	48	PTPRZ1
4.417e-02	-3.12	transmembrane receptor protein phosphatase activity	molecular function	GO:0019198	17	1	18094	48	PTPRZ1
4.424e-02	-3.12	Ig-like_fold	interpro domains	IPR013783	721	5	18521	50	LSAMP,NTRK2,PTPRZ1,NTM,LIFR
4.432e-02	-3.12	Bone Morphogenic Protein (BMP) Signalling and Regulation	WikiPathways	WP1425	12	1	5310	20	BMPR1B
4.432e-02	-3.12	MFAP5-mediated ovarian cancer cell motility and invasiveness	WikiPathways	WP3301	12	1	5310	20	RYR3
4.437e-02	-3.12	central_nervous_system-brain-glioma-astrocytoma_Grade_IV	COSMIC cancer mutations	central_nervous_system-brain-glioma-astrocytoma_Grade_IV	15813	50	16828	50	RORA,PITPNC1,LIFR,GPM6A,MGAT4C,FBXL7,PARD3B,SOX5,RYR3,ADCY2,FMN2,SLC1A3,SLC4A4,SORBS1,ZBTB20,GLIS3,ITPR2,PARD3,NHSL1,MACF1,ABLIM1,NTM,NKAIN3,NFIA,TRPM3,SPARCL1,AQP4,MAML2,DTNA,NTRK2,SLC1A2,PTPRZ1,NRG3,NEBL,TRPS1,MSI2,CSGALNACT1,QKI,CDH20,RFX4,SASH1,NPAS3,CTNND2,GPC5,ATP13A4,LSAMP,PPP2R2B,PRKCA,DCLK2,BMPR1B
4.445e-02	-3.11	cell projection organization	biological process	GO:0030030	1200	7	18204	50	PARD3,ABLIM1,GPM6A,BMPR1B,RFX4,CTNND2,PTPRZ1
4.445e-02	-3.11	Glycosaminoglycan metabolism	REACTOME pathways	R-HSA-1630316	124	2	10285	28	GPC5,CSGALNACT1
4.449e-02	-3.11	tight junction	cellular component	GO:0070160	131	2	19108	49	PARD3B,PARD3
4.468e-02	-3.11	NCOA2 (nuclear receptor coactivator 2)	protein interactions	10499	131	2	19454	50	NFIA,RORA
4.468e-02	-3.11	TRPS1 (transcriptional repressor GATA binding 1)	protein interactions	7227	131	2	19454	50	SOX5,NFIA
4.468e-02	-3.11	ZNF609 (zinc finger protein 609)	protein interactions	23060	131	2	19454	50	NFIA,SOX5
4.477e-02	-3.11	ZnF_GATA	smart domains	SM00401	12	1	9717	37	TRPS1
4.477e-02	-3.11	DWA	smart domains	SM00523	12	1	9717	37	NFIA
4.490e-02	-3.10	Carb_anhydrase	pfam domains	PF00194	17	1	17795	48	PTPRZ1
4.490e-02	-3.10	ZZ	pfam domains	PF00569	17	1	17795	48	DTNA
4.492e-02	-3.10	muscle cell differentiation	biological process	GO:0042692	289	3	18204	50	NEBL,RORA,QKI
4.493e-02	-3.10	CA_dom	interpro domains	IPR001148	17	1	18521	50	PTPRZ1
4.493e-02	-3.10	A/G_cyclase_CS	interpro domains	IPR018297	17	1	18521	50	ADCY2
4.493e-02	-3.10	CA_dom_sf	interpro domains	IPR036398	17	1	18521	50	PTPRZ1
4.519e-02	-3.10	protein phosphatase type 2A complex	cellular component	GO:0000159	18	1	19108	49	PPP2R2B
4.525e-02	-3.10	acral	COSMIC cancer mutations	acral	268	3	16828	50	CDH20,PARD3,FMN2
4.529e-02	-3.09	ACAP1 (ArfGAP with coiled-coil, ankyrin repeat and PH domains 1)	protein interactions	9744	18	1	19454	50	NEBL
4.529e-02	-3.09	TTC29 (tetratricopeptide repeat domain 29)	protein interactions	83894	18	1	19454	50	MACF1
4.529e-02	-3.09	OPCML (opioid binding protein/cell adhesion molecule like)	protein interactions	4978	18	1	19454	50	NTM
4.529e-02	-3.09	NECTIN1 (nectin cell adhesion molecule 1)	protein interactions	5818	18	1	19454	50	PARD3
4.529e-02	-3.09	SERTAD4 (SERTA domain containing 4)	protein interactions	56256	18	1	19454	50	PPP2R2B
4.529e-02	-3.09	KLHL1 (kelch like family member 1)	protein interactions	57626	18	1	19454	50	BMPR1B
4.529e-02	-3.09	Tgfbr1 (transforming growth factor, beta receptor I)	protein interactions	21812	18	1	19454	50	BMPR1B
4.529e-02	-3.09	NKIRAS1 (NFKB inhibitor interacting Ras like 1)	protein interactions	28512	18	1	19454	50	BMPR1B
4.529e-02	-3.09	Cnot2 (CCR4-NOT transcription complex, subunit 2)	protein interactions	72068	18	1	19454	50	MACF1
4.529e-02	-3.09	SELL (selectin L)	protein interactions	6402	18	1	19454	50	PRKCA
4.530e-02	-3.09	IVL (involucrin)	protein interactions	3713	132	2	19454	50	PPP2R2B,CSGALNACT1
4.532e-02	-3.09	TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)	REACTOME pathways	R-HSA-2173791	17	1	10285	28	PARD3
4.532e-02	-3.09	Elevation of cytosolic Ca2+ levels	REACTOME pathways	R-HSA-139853	17	1	10285	28	ITPR2
4.532e-02	-3.09	PKA activation in glucagon signalling	REACTOME pathways	R-HSA-164378	17	1	10285	28	ADCY2
4.532e-02	-3.09	Trafficking of GluR2-containing AMPA receptors	REACTOME pathways	R-HSA-416993	17	1	10285	28	PRKCA
4.532e-02	-3.09	PKA-mediated phosphorylation of CREB	REACTOME pathways	R-HSA-111931	17	1	10285	28	ADCY2
4.557e-02	-3.09	cytoskeletal protein binding	molecular function	GO:0008092	989	6	18094	48	FMN2,DCLK2,MACF1,SORBS1,ABLIM1,NEBL
4.558e-02	-3.09	cellular process	biological process	GO:0009987	14996	46	18204	50	MSI2,CSGALNACT1,BMPR1B,NRG3,SOX5,RFX4,SLC4A4,SPARCL1,SORBS1,NTRK2,PTPRZ1,ITPR2,LSAMP,ABLIM1,FMN2,LIFR,NTM,PARD3,GLIS3,ADCY2,PRKCA,GPC5,DTNA,GPM6A,MGAT4C,AQP4,TRPM3,QKI,SLC1A3,MAML2,PITPNC1,RORA,SLC1A2,NEBL,FBXL7,RYR3,CTNND2,NHSL1,ATP13A4,PARD3B,PPP2R2B,CDH20,MACF1,NFIA,ZBTB20,DCLK2
4.560e-02	-3.09	positive regulation of lipid metabolic process	biological process	GO:0045834	124	2	18204	50	SORBS1,ZBTB20
4.570e-02	-3.09	ureter development	biological process	GO:0072189	17	1	18204	50	NFIA
4.570e-02	-3.09	positive regulation of glycogen metabolic process	biological process	GO:0070875	17	1	18204	50	SORBS1
4.570e-02	-3.09	protein trimerization	biological process	GO:0070206	17	1	18204	50	SLC1A2
4.570e-02	-3.09	viral genome replication	biological process	GO:0019079	17	1	18204	50	NFIA
4.570e-02	-3.09	cellular response to ATP	biological process	GO:0071318	17	1	18204	50	RYR3
4.570e-02	-3.09	cGMP metabolic process	biological process	GO:0046068	17	1	18204	50	RORA
4.570e-02	-3.09	T-helper 17 type immune response	biological process	GO:0072538	17	1	18204	50	RORA
4.570e-02	-3.09	retinal rod cell differentiation	biological process	GO:0060221	17	1	18204	50	NTRK2
4.570e-02	-3.09	heparin metabolic process	biological process	GO:0030202	17	1	18204	50	CSGALNACT1
4.607e-02	-3.08	PRKCI (protein kinase C iota)	protein interactions	5584	312	3	19454	50	PARD3,NTRK2,PRKCA
4.607e-02	-3.08	response to hypoxia	biological process	GO:0001666	292	3	18204	50	RORA,ITPR2,FMN2
4.609e-02	-3.08	ovary-carcinoma-mucinous_carcinoma	COSMIC cancer mutations	ovary-carcinoma-mucinous_carcinoma	456	4	16828	50	BMPR1B,NTRK2,PRKCA,DCLK2
4.623e-02	-3.07	ion binding	molecular function	GO:0043167	6007	22	18094	48	ATP13A4,TRPS1,MGAT4C,RORA,SPARCL1,DCLK2,ADCY2,ABLIM1,SLC1A3,NTRK2,PRKCA,PARD3,ITPR2,BMPR1B,SLC1A2,ZBTB20,GLIS3,PITPNC1,MACF1,DTNA,RYR3,CSGALNACT1
4.626e-02	-3.07	actomyosin structure organization	biological process	GO:0031032	125	2	18204	50	NEBL,SORBS1
4.629e-02	-3.07	LPA4-mediated signaling events	Pathway Interaction DB	lpa4_pathway	15	1	2226	7	ADCY2
4.631e-02	-3.07	cellular response to growth factor stimulus	biological process	GO:0071363	494	4	18204	50	NFIA,BMPR1B,NTRK2,SOX5
4.645e-02	-3.07	ovary	COSMIC cancer mutations	ovary	14770	48	16828	50	RFX4,CDH20,QKI,CSGALNACT1,MSI2,TRPS1,NEBL,NRG3,BMPR1B,DCLK2,PRKCA,PPP2R2B,LSAMP,ATP13A4,CTNND2,GPC5,NPAS3,SASH1,PARD3,ZBTB20,ITPR2,GLIS3,SORBS1,SLC4A4,ADCY2,SLC1A3,FMN2,RYR3,SOX5,PARD3B,FBXL7,MGAT4C,GPM6A,LIFR,RORA,SLC1A2,PTPRZ1,NTRK2,DTNA,MAML2,AQP4,SPARCL1,TRPM3,NKAIN3,NTM,ABLIM1,MACF1,NHSL1
4.653e-02	-3.07	NUFIP1 (nuclear FMR1 interacting protein 1)	protein interactions	26747	134	2	19454	50	GPM6A,NTM
4.671e-02	-3.06	mucinous_carcinoma	COSMIC cancer mutations	mucinous_carcinoma	458	4	16828	50	BMPR1B,NTRK2,PRKCA,DCLK2
4.671e-02	-3.06	phosphatidylcholine transporter activity	molecular function	GO:0008525	18	1	18094	48	PITPNC1
4.671e-02	-3.06	transmembrane receptor protein tyrosine kinase activator activity	molecular function	GO:0030297	18	1	18094	48	NRG3
4.680e-02	-3.06	central_nervous_system-medulla-primitive_neuroectodermal_tumour-medulloblastoma-large_cell	COSMIC cancer mutations	central_nervous_system-medulla-primitive_neuroectodermal_tumour-medulloblastoma-large_cell	14773	48	16828	50	FMN2,SLC1A3,ADCY2,ITPR2,ZBTB20,GLIS3,SORBS1,SLC4A4,PARD3,PITPNC1,RORA,LIFR,FBXL7,MGAT4C,GPM6A,PARD3B,SOX5,RYR3,DTNA,SLC1A2,PTPRZ1,NTRK2,NHSL1,NTM,ABLIM1,MACF1,TRPM3,SPARCL1,NFIA,AQP4,MSI2,CSGALNACT1,QKI,CDH20,RFX4,NEBL,NRG3,TRPS1,LSAMP,PPP2R2B,DCLK2,PRKCA,BMPR1B,SASH1,NPAS3,CTNND2,GPC5,ATP13A4
4.680e-02	-3.06	central_nervous_system-medulla-primitive_neuroectodermal_tumour-medulloblastoma-desmoplastic	COSMIC cancer mutations	central_nervous_system-medulla-primitive_neuroectodermal_tumour-medulloblastoma-desmoplastic	14773	48	16828	50	PRKCA,DCLK2,LSAMP,PPP2R2B,BMPR1B,NPAS3,CTNND2,GPC5,SASH1,ATP13A4,MSI2,CDH20,RFX4,CSGALNACT1,QKI,TRPS1,NRG3,NEBL,DTNA,NTRK2,SLC1A2,PTPRZ1,MACF1,NTM,ABLIM1,NHSL1,AQP4,NFIA,TRPM3,SPARCL1,SORBS1,SLC4A4,ZBTB20,ITPR2,GLIS3,SLC1A3,ADCY2,FMN2,PARD3,LIFR,RORA,PITPNC1,PARD3B,SOX5,RYR3,GPM6A,MGAT4C,FBXL7
4.680e-02	-3.06	central_nervous_system-medulla-primitive_neuroectodermal_tumour-medulloblastoma	COSMIC cancer mutations	central_nervous_system-medulla-primitive_neuroectodermal_tumour-medulloblastoma	14773	48	16828	50	MSI2,CSGALNACT1,QKI,CDH20,RFX4,NEBL,NRG3,TRPS1,LSAMP,PPP2R2B,DCLK2,PRKCA,BMPR1B,SASH1,NPAS3,CTNND2,GPC5,ATP13A4,SLC1A3,FMN2,ADCY2,ITPR2,GLIS3,ZBTB20,SORBS1,SLC4A4,PARD3,PITPNC1,RORA,LIFR,FBXL7,MGAT4C,GPM6A,PARD3B,SOX5,RYR3,DTNA,PTPRZ1,SLC1A2,NTRK2,NHSL1,NTM,ABLIM1,MACF1,TRPM3,SPARCL1,NFIA,AQP4
4.680e-02	-3.06	central_nervous_system-medulla-primitive_neuroectodermal_tumour-medulloblastoma-classic	COSMIC cancer mutations	central_nervous_system-medulla-primitive_neuroectodermal_tumour-medulloblastoma-classic	14773	48	16828	50	CTNND2,GPC5,NPAS3,SASH1,ATP13A4,PRKCA,DCLK2,PPP2R2B,LSAMP,BMPR1B,TRPS1,NRG3,NEBL,MSI2,RFX4,CDH20,QKI,CSGALNACT1,MACF1,ABLIM1,NTM,NHSL1,AQP4,NFIA,SPARCL1,TRPM3,DTNA,NTRK2,PTPRZ1,SLC1A2,LIFR,RORA,PITPNC1,RYR3,SOX5,PARD3B,GPM6A,FBXL7,MGAT4C,SORBS1,SLC4A4,ZBTB20,GLIS3,ITPR2,SLC1A3,FMN2,ADCY2,PARD3
4.691e-02	-3.06	classic	COSMIC cancer mutations	classic	14774	48	16828	50	SOX5,PARD3B,RYR3,GPM6A,MGAT4C,FBXL7,LIFR,RORA,PITPNC1,PARD3,SLC4A4,SORBS1,GLIS3,ITPR2,ZBTB20,FMN2,ADCY2,SLC1A3,AQP4,NFIA,TRPM3,SPARCL1,MACF1,NTM,ABLIM1,NHSL1,NTRK2,PTPRZ1,SLC1A2,DTNA,TRPS1,NRG3,NEBL,CDH20,RFX4,CSGALNACT1,QKI,MSI2,ATP13A4,NPAS3,GPC5,CTNND2,SASH1,BMPR1B,PRKCA,DCLK2,LSAMP,PPP2R2B
4.714e-02	-3.05	lung-middle_lobe-carcinoma-adenocarcinoma	COSMIC cancer mutations	lung-middle_lobe-carcinoma-adenocarcinoma	1368	8	16828	50	SASH1,MACF1,CTNND2,ITPR2,TRPM3,RYR3,ATP13A4,PARD3B
4.715e-02	-3.05	DVL2 (dishevelled segment polarity protein 2)	protein interactions	1856	531	4	19454	50	MACF1,LIFR,PARD3,PRKCA
4.716e-02	-3.05	SOX15 (SRY-box transcription factor 15)	protein interactions	6665	135	2	19454	50	TRPS1,NFIA
4.737e-02	-3.05	medulla	COSMIC cancer mutations	medulla	14778	48	16828	50	DTNA,NTRK2,SLC1A2,PTPRZ1,MACF1,NTM,ABLIM1,NHSL1,AQP4,NFIA,SPARCL1,TRPM3,SORBS1,SLC4A4,ITPR2,ZBTB20,GLIS3,FMN2,SLC1A3,ADCY2,PARD3,LIFR,RORA,PITPNC1,RYR3,PARD3B,SOX5,GPM6A,MGAT4C,FBXL7,PRKCA,DCLK2,PPP2R2B,LSAMP,BMPR1B,CTNND2,GPC5,NPAS3,SASH1,ATP13A4,MSI2,RFX4,CDH20,QKI,CSGALNACT1,TRPS1,NRG3,NEBL
4.740e-02	-3.05	breast-carcinoma-ER-PR-positive_carcinoma	COSMIC cancer mutations	breast-carcinoma-ER-PR-positive_carcinoma	1881	10	16828	50	PPP2R2B,MSI2,NRG3,NPAS3,MAML2,LIFR,PRKCA,FBXL7,BMPR1B,NTRK2
4.740e-02	-3.05	ER-PR-positive_carcinoma	COSMIC cancer mutations	ER-PR-positive_carcinoma	1881	10	16828	50	MAML2,PRKCA,LIFR,NPAS3,NRG3,PPP2R2B,MSI2,NTRK2,BMPR1B,FBXL7
4.745e-02	-3.05	bone-extraskeletal-Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour	COSMIC cancer mutations	bone-extraskeletal-Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour	891	6	16828	50	ABLIM1,ITPR2,NPAS3,PTPRZ1,PPP2R2B,SPARCL1
4.747e-02	-3.05	Growth Hormone Signaling Pathway	SMPDB pathways	SMP0063807	22	1	1369	3	PRKCA
4.748e-02	-3.05	Cation_ATPase_N	pfam domains	PF00690	18	1	17795	48	ATP13A4
4.748e-02	-3.05	Guanylate_cyc	pfam domains	PF00211	18	1	17795	48	ADCY2
4.748e-02	-3.05	desmoplastic	COSMIC cancer mutations	desmoplastic	14779	48	16828	50	ATP13A4,SASH1,GPC5,CTNND2,NPAS3,BMPR1B,PPP2R2B,LSAMP,PRKCA,DCLK2,NRG3,NEBL,TRPS1,QKI,CSGALNACT1,RFX4,CDH20,MSI2,NFIA,SPARCL1,TRPM3,AQP4,NHSL1,MACF1,NTM,ABLIM1,NTRK2,PTPRZ1,SLC1A2,DTNA,GPM6A,FBXL7,MGAT4C,RYR3,PARD3B,SOX5,RORA,PITPNC1,LIFR,PARD3,SLC1A3,FMN2,ADCY2,SLC4A4,SORBS1,ITPR2,GLIS3,ZBTB20
4.752e-02	-3.05	A/G_cyclase	interpro domains	IPR001054	18	1	18521	50	ADCY2
4.752e-02	-3.05	ATPase_P-typ_cation-transptr_N	interpro domains	IPR004014	18	1	18521	50	ATP13A4
4.752e-02	-3.05	Leu-rich_rpt_Cys-con_subtyp	interpro domains	IPR006553	18	1	18521	50	FBXL7
4.752e-02	-3.05	Nucleotide_cyclase	interpro domains	IPR029787	18	1	18521	50	ADCY2
4.760e-02	-3.05	regulation of myeloid leukocyte differentiation	biological process	GO:0002761	127	2	18204	50	PRKCA,QKI
4.760e-02	-3.05	response to amino acid	biological process	GO:0043200	127	2	18204	50	SLC1A2,NTRK2
4.764e-02	-3.04	parallel fiber to Purkinje cell synapse	cellular component	GO:0098688	19	1	19108	49	GPM6A
4.774e-02	-3.04	RIT2 (Ras like without CAAX 2)	protein interactions	6014	19	1	19454	50	DTNA
4.774e-02	-3.04	CNTNAP4 (contactin associated protein family member 4)	protein interactions	85445	19	1	19454	50	MACF1
4.774e-02	-3.04	GCHFR (GTP cyclohydrolase I feedback regulator)	protein interactions	2644	19	1	19454	50	NEBL
4.774e-02	-3.04	TNR (tenascin R)	protein interactions	7143	19	1	19454	50	PTPRZ1
4.774e-02	-3.04	JSRP1 (junctional sarcoplasmic reticulum protein 1)	protein interactions	126306	19	1	19454	50	PRKCA
4.774e-02	-3.04	PHYHIPL (phytanoyl-CoA 2-hydroxylase interacting protein like)	protein interactions	84457	19	1	19454	50	GPM6A
4.774e-02	-3.04	INKA1 (inka box actin regulator 1)	protein interactions	389119	19	1	19454	50	ZBTB20
4.774e-02	-3.04	SPZ1 (spermatogenic leucine zipper 1)	protein interactions	84654	19	1	19454	50	DTNA
4.774e-02	-3.04	RRAD (RRAD, Ras related glycolysis inhibitor and calcium channel regulator)	protein interactions	6236	19	1	19454	50	PRKCA
4.774e-02	-3.04	TRPV6 (transient receptor potential cation channel subfamily V member 6)	protein interactions	55503	19	1	19454	50	PRKCA
4.774e-02	-3.04	PLA2G4E (phospholipase A2 group IVE)	protein interactions	123745	19	1	19454	50	PPP2R2B
4.793e-02	-3.04	Cell-type Dependent Selectivity of CCK2R Signaling	WikiPathways	WP3679	13	1	5310	20	RYR3
4.802e-02	-3.04	PK_Tyr_Ser-Thr	pfam domains	PF07714	130	2	17795	48	BMPR1B,NTRK2
4.804e-02	-3.04	carboxylic acid transport	biological process	GO:0046942	297	3	18204	50	SLC1A3,SLC1A2,NTRK2
4.827e-02	-3.03	glial cell development	biological process	GO:0021782	128	2	18204	50	NTRK2,PARD3
4.832e-02	-3.03	positive regulation of circadian rhythm	biological process	GO:0042753	18	1	18204	50	RORA
4.832e-02	-3.03	dendritic spine morphogenesis	biological process	GO:0060997	18	1	18204	50	CTNND2
4.832e-02	-3.03	positive regulation of myelination	biological process	GO:0031643	18	1	18204	50	PARD3
4.832e-02	-3.03	negative regulation of anoikis	biological process	GO:2000811	18	1	18204	50	NTRK2
4.832e-02	-3.03	cardiac myofibril assembly	biological process	GO:0055003	18	1	18204	50	NEBL
4.842e-02	-3.03	TBL1X (transducin beta like 1 X-linked)	protein interactions	6907	137	2	19454	50	NFIA,SOX5
4.843e-02	-3.03	organic acid transport	biological process	GO:0015849	298	3	18204	50	SLC1A3,SLC1A2,NTRK2
4.859e-02	-3.02	ovary-carcinoma-endometrioid_carcinoma	COSMIC cancer mutations	ovary-carcinoma-endometrioid_carcinoma	464	4	16828	50	BMPR1B,NTRK2,PRKCA,DCLK2
4.859e-02	-3.02	lower_third	COSMIC cancer mutations	lower_third	7961	30	16828	50	PTPRZ1,NTRK2,DCLK2,PRKCA,ATP13A4,AQP4,TRPM3,NPAS3,CTNND2,GPC5,MACF1,SASH1,CDH20,PARD3,QKI,ITPR2,ZBTB20,SORBS1,SLC4A4,ADCY2,FMN2,SOX5,PARD3B,RYR3,MGAT4C,TRPS1,LIFR,NEBL,NRG3,RORA
4.859e-02	-3.02	human chr18q12.1	chromosome location	human chr18q12.1	26	1	26134	50	DTNA
4.883e-02	-3.02	G Protein Signaling Pathways	WikiPathways	WP35	95	2	5310	20	PRKCA,ADCY2
4.894e-02	-3.02	response to organophosphorus	biological process	GO:0046683	129	2	18204	50	ITPR2,RYR3
4.911e-02	-3.01	sequence-specific double-stranded DNA binding	molecular function	GO:1990837	1547	8	18094	48	RFX4,ZBTB20,GLIS3,NPAS3,TRPS1,SOX5,RORA,NFIA
4.923e-02	-3.01	regulation of epithelial cell migration	biological process	GO:0010632	300	3	18204	50	MACF1,SASH1,PRKCA
4.924e-02	-3.01	transmembrane receptor protein serine/threonine kinase activity	molecular function	GO:0004675	19	1	18094	48	BMPR1B
4.924e-02	-3.01	water transmembrane transporter activity	molecular function	GO:0005372	19	1	18094	48	AQP4
4.932e-02	-3.01	FH2	prosite domains	PS51444	15	1	12186	41	FMN2
4.935e-02	-3.01	central_nervous_system-optic_nerve-glioma-astrocytoma_Grade_I	COSMIC cancer mutations	central_nervous_system-optic_nerve-glioma-astrocytoma_Grade_I	17	1	16828	50	QKI
4.935e-02	-3.01	optic_nerve	COSMIC cancer mutations	optic_nerve	17	1	16828	50	QKI
4.936e-02	-3.01	Alpha carbonic anhydrase	gene3d domains	3.10.200.10	17	1	14470	43	PTPRZ1
4.948e-02	-3.01	haematopoietic_and_lymphoid_tissue-abdomen-lymphoid_neoplasm-diffuse_large_B_cell_lymphoma	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue-abdomen-lymphoid_neoplasm-diffuse_large_B_cell_lymphoma	120	2	16828	50	FMN2,CTNND2
4.951e-02	-3.01	monoatomic cation homeostasis	biological process	GO:0055080	505	4	18204	50	SLC4A4,RYR3,ATP13A4,SLC1A3
4.955e-02	-3.00	Serotonergic synapse	KEGG pathways	hsa04726	112	2	7161	23	PRKCA,ITPR2
4.956e-02	-3.00	middle_lobe	COSMIC cancer mutations	middle_lobe	1382	8	16828	50	ATP13A4,PARD3B,RYR3,TRPM3,ITPR2,CTNND2,MACF1,SASH1
4.968e-02	-3.00	SPCS2 (signal peptidase complex subunit 2)	protein interactions	9789	139	2	19454	50	GPC5,MGAT4C
4.987e-02	-3.00	ligand-gated monoatomic cation channel activity	molecular function	GO:0099094	135	2	18094	48	RYR3,ITPR2