Gene Ontology Enrichment Results

Homer de novo Motif Enrichment Results
Known Motif Enrichment Results

Text file version of complete results (i.e. open with Excel)

biological process: Functional groupings of proteins (Gene Ontology)

molecular function: Mechanistic actions of proteins (Gene Ontology)

cellular component: Protein localization (Gene Ontology)

chromosome location: Genes with similar chromosome localization (NCBI Gene)

KEGG pathways: Groups of proteins in the same pathways (KEGG)

protein interactions: "Proteins interacting with a common protein (BIND, EcoCyc, HPRD)" (NCBI Gene)

interpro domains: Proteins with similar domains and features (Interpro)

pfam domains: Proteins with similar domains and features (Pfam)

smart domains: Proteins with similar domains and features (SMART)

gene3d domains: Proteins with similar domains and features (Gene3D)

prosite domains: Proteins with similar domains and features (Prosite)

prints domains: Proteins with similar domains and features (PRINTS)

MSigDB lists: "Genes sets for pathways, factor/miRNA target predictions, expression patterns, etc." (MSigDB)

BIOCYC pathways: Groups of proteins in the same pathways (BIOCYC)

COSMIC cancer mutations: Genes mutated in similar cancers (COSMIC)

GWAS genes: Genes mutated in similar diseases (GWAS Catalog)

Lipid Maps pathways: Groups of proteins in the same lipid pathways (Lipid Maps/Biosystems)

Pathway Interaction DB: Groups of proteins in the same pathways (Pathway Interaction Database)

REACTOME pathways: Groups of proteins in the same pathways (REACTOME)

SMPDB pathways: Groups of proteins in the same pathways (SMPDB)

WikiPathways: Groups of proteins in the same pathways (Wikipathways)

Enriched Categories

P-value	ln(P)	Term	GO Tree	GO ID	# of Genes in Term	# of Target Genes in Term	# of Total Genes	# of Target Genes	Common Genes
8.346e-11	-23.21	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-Burkitt_lymphoma	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-Burkitt_lymphoma	2119	25	16828	49	SLC1A2,BMPR1B,ADCY2,SOX5,CTNND2,CPE,ITPR2,FBXL7,CSGALNACT1,NKAIN3,LSAMP,NRG3,NTRK2,GPM6A,MAML2,PARD3,SLC1A3,NHSL1,NPAS3,GPC5,RYR3,ATP13A4,FMN2,RFX4,PPP2R2B
8.346e-11	-23.21	Burkitt_lymphoma	COSMIC cancer mutations	Burkitt_lymphoma	2119	25	16828	49	CPE,SOX5,CTNND2,ADCY2,NRG3,LSAMP,CSGALNACT1,NKAIN3,FBXL7,ITPR2,SLC1A2,BMPR1B,NPAS3,NHSL1,PPP2R2B,RYR3,ATP13A4,RFX4,FMN2,GPC5,MAML2,GPM6A,NTRK2,SLC1A3,PARD3
2.337e-10	-22.18	acute_lymphoblastic_B_cell_leukaemia	COSMIC cancer mutations	acute_lymphoblastic_B_cell_leukaemia	3828	32	16828	49	PPP2R2B,FMN2,ATP13A4,RYR3,GPC5,MAML2,GPM6A,NTRK2,SLC1A3,NTM,ZBTB20,PARD3,CPE,CTNND2,SOX5,ADCY2,NEBL,NRG3,LSAMP,NKAIN3,CSGALNACT1,PTPRZ1,FBXL7,ITPR2,MGAT4C,GLIS3,NFIA,SLC1A2,BMPR1B,TNIK,SLC4A4,RORA
2.337e-10	-22.18	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-acute_lymphoblastic_B_cell_leukaemia	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-acute_lymphoblastic_B_cell_leukaemia	3828	32	16828	49	ADCY2,NEBL,CPE,CTNND2,SOX5,PTPRZ1,FBXL7,ITPR2,LSAMP,NRG3,NKAIN3,CSGALNACT1,MGAT4C,GLIS3,TNIK,SLC4A4,RORA,NFIA,BMPR1B,SLC1A2,FMN2,RYR3,ATP13A4,GPC5,PPP2R2B,GPM6A,NTRK2,MAML2,NTM,PARD3,ZBTB20,SLC1A3
6.000e-10	-21.23	prostate-carcinoma	COSMIC cancer mutations	prostate-carcinoma	9000	46	16828	49	SPARCL1,GPM6A,MACF1,MAML2,ZBTB20,MSI2,NTM,SLC1A3,NHSL1,NPAS3,GPC5,RFX4,PPP2R2B,GLIS3,PARD3B,BMPR1B,DTNA,SLC1A2,NFIA,SFXN5,CSGALNACT1,LSAMP,NTRK2,SORBS1,PARD3,TRPS1,PITPNC1,ATP13A4,RYR3,FMN2,RORA,SLC4A4,CDH20,TNIK,ABLIM1,ADCY2,NEBL,SOX5,CTNND2,CPE,ITPR2,FBXL7,PTPRZ1,NKAIN3,FUT9,NRG3
9.808e-09	-18.44	PRNP (prion protein (Kanno blood group))	protein interactions	5621	1118	16	19454	50	CPE,LSAMP,SORBS1,SLC1A3,TRPS1,ATP1A2,MACF1,ABLIM1,AQP4,GPM6A,SLC4A4,SPARCL1,NHSL1,PTPRZ1,MSI2,MAML2
1.166e-08	-18.27	diffuse_large_B_cell_lymphoma	COSMIC cancer mutations	diffuse_large_B_cell_lymphoma	4151	31	16828	49	MACF1,GPM6A,NTRK2,SPARCL1,MAML2,TRPS1,PARD3,SLC1A3,AQP4,ATP1A2,FMN2,RYR3,ATP13A4,GPC5,PPP2R2B,CDH20,TNIK,RORA,DTNA,SLC1A2,ADCY2,NEBL,CPE,CTNND2,SOX5,FBXL7,ITPR2,NRG3,LSAMP,CSGALNACT1,NKAIN3
2.195e-08	-17.63	central_nervous_system-brainstem-glioma-astrocytoma_Grade_IV	COSMIC cancer mutations	central_nervous_system-brainstem-glioma-astrocytoma_Grade_IV	2531	24	16828	49	SLC1A3,PARD3,ZBTB20,MAML2,GPM6A,PPP2R2B,GPC5,RYR3,ATP13A4,FMN2,RORA,CDH20,TNIK,NKAIN3,LSAMP,NRG3,ITPR2,FBXL7,PTPRZ1,SOX5,CTNND2,CPE,SFXN5,ADCY2
2.342e-08	-17.57	cerebellum	COSMIC cancer mutations	cerebellum	769	14	16828	49	ITPR2,GPC5,PTPRZ1,RYR3,NRG3,NEBL,CTNND2,CPE,NPAS3,PARD3,PARD3B,ABLIM1,NTRK2,MAML2
2.815e-08	-17.39	central_nervous_system-brain-primitive_neuroectodermal_tumour-medulloblastoma	COSMIC cancer mutations	central_nervous_system-brain-primitive_neuroectodermal_tumour-medulloblastoma	7205	40	16828	49	CPE,SOX5,CTNND2,ADCY2,NEBL,SFXN5,NRG3,LSAMP,CSGALNACT1,NKAIN3,FBXL7,PTPRZ1,ITPR2,GLIS3,ABLIM1,SLC1A2,NFIA,TNIK,PARD3B,RORA,SLC4A4,NPAS3,NHSL1,PITPNC1,PPP2R2B,ATP13A4,RYR3,FMN2,RFX4,GPC5,SORBS1,MAML2,NTRK2,GPM6A,MACF1,SLC1A3,NTM,PARD3,ZBTB20,TRPS1
2.907e-08	-17.35	central_nervous_system-cerebellum-primitive_neuroectodermal_tumour-medulloblastoma-SHH_subtype	COSMIC cancer mutations	central_nervous_system-cerebellum-primitive_neuroectodermal_tumour-medulloblastoma-SHH_subtype	653	13	16828	49	NTRK2,MAML2,PARD3B,PARD3,ABLIM1,NEBL,NPAS3,CPE,CTNND2,RYR3,PTPRZ1,ITPR2,NRG3
2.915e-08	-17.35	chondroblastoma	COSMIC cancer mutations	chondroblastoma	534	12	16828	49	GPM6A,SOX5,CTNND2,ADCY2,SFXN5,PPP2R2B,NKAIN3,NRG3,LSAMP,GPC5,RYR3,FMN2
2.960e-08	-17.34	SHH_subtype	COSMIC cancer mutations	SHH_subtype	654	13	16828	49	NRG3,ABLIM1,PTPRZ1,PARD3B,RYR3,ITPR2,PARD3,CPE,NPAS3,MAML2,CTNND2,NTRK2,NEBL
4.446e-08	-16.93	mantle_cell_lymphoma	COSMIC cancer mutations	mantle_cell_lymphoma	2849	25	16828	49	NKAIN3,NRG3,LSAMP,ITPR2,FBXL7,CTNND2,SOX5,CPE,NEBL,SFXN5,ADCY2,SLC1A2,PARD3B,PPP2R2B,GPC5,RFX4,FMN2,ATP13A4,RYR3,SLC1A3,TRPS1,PARD3,MAML2,NTRK2,GPM6A
5.055e-08	-16.80	brainstem	COSMIC cancer mutations	brainstem	3102	26	16828	49	PTPRZ1,FBXL7,ITPR2,NRG3,LSAMP,NKAIN3,SFXN5,ADCY2,CPE,CTNND2,SOX5,CDH20,TNIK,RORA,SLC1A2,FMN2,RYR3,ATP13A4,GPC5,PPP2R2B,NPAS3,ZBTB20,PARD3,SLC1A3,GPM6A,MAML2
1.027e-07	-16.09	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-mantle_cell_lymphoma	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-mantle_cell_lymphoma	2737	24	16828	49	PARD3B,SLC1A2,SFXN5,ADCY2,NEBL,SOX5,CTNND2,CPE,ITPR2,FBXL7,NKAIN3,NRG3,LSAMP,GPM6A,NTRK2,MAML2,PARD3,TRPS1,SLC1A3,GPC5,RYR3,RFX4,FMN2,PPP2R2B
1.086e-07	-16.04	lymph_node	COSMIC cancer mutations	lymph_node	1703	19	16828	49	GPC5,ITPR2,ATP13A4,RYR3,NRG3,LSAMP,SFXN5,NEBL,CTNND2,SOX5,TRPS1,PARD3,PARD3B,TNIK,DTNA,SLC1A3,GPM6A,NTRK2,MAML2
1.132e-07	-15.99	acute_myeloid_leukaemia_therapy_related	COSMIC cancer mutations	acute_myeloid_leukaemia_therapy_related	1523	18	16828	49	MAML2,NTRK2,SLC1A3,RORA,PARD3,SOX5,CTNND2,NEBL,ADCY2,LSAMP,NRG3,PPP2R2B,NKAIN3,FBXL7,RYR3,FMN2,ITPR2,GPC5
1.132e-07	-15.99	haematopoietic_and_lymphoid_tissue-haematopoietic_neoplasm-acute_myeloid_leukaemia_therapy_related	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue-haematopoietic_neoplasm-acute_myeloid_leukaemia_therapy_related	1523	18	16828	49	GPC5,ITPR2,RYR3,FBXL7,FMN2,NKAIN3,PPP2R2B,LSAMP,NRG3,ADCY2,NEBL,SOX5,CTNND2,PARD3,RORA,SLC1A3,NTRK2,MAML2
1.245e-07	-15.90	CTNNA1 (catenin alpha 1)	protein interactions	1495	325	9	19454	50	NEBL,PARD3,MACF1,TNIK,NHSL1,DTNA,SORBS1,CTNNA2,ABLIM1
1.593e-07	-15.65	lymphoid_neoplasm	COSMIC cancer mutations	lymphoid_neoplasm	12233	49	16828	49	SOX5,CTNND2,CPE,ADCY2,NEBL,NKAIN3,NRG3,FUT9,ITPR2,FBXL7,PTPRZ1,MGAT4C,ABLIM1,RORA,SLC4A4,CDH20,TNIK,ATP1A2,PITPNC1,RYR3,ATP13A4,FMN2,SORBS1,NTRK2,PARD3,TRPS1,SFXN5,CSGALNACT1,LSAMP,GLIS3,SLC1A2,DTNA,BMPR1B,NFIA,PARD3B,NHSL1,NPAS3,AQP4,PPP2R2B,GPC5,RFX4,MAML2,SPARCL1,GPM6A,MACF1,SLC1A3,ZBTB20,MSI2,NTM
1.813e-07	-15.52	haematopoietic_and_lymphoid_tissue-haematopoietic_neoplasm	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue-haematopoietic_neoplasm	764	13	16828	49	PARD3,SLC1A2,NTRK2,MAML2,RYR3,FBXL7,GPC5,NRG3,LSAMP,NKAIN3,ADCY2,ATP1A2,SOX5
2.356e-07	-15.26	angiosarcoma	COSMIC cancer mutations	angiosarcoma	2192	21	16828	49	MAML2,GPM6A,NTRK2,SLC1A2,SLC1A3,PARD3,CDH20,CTNND2,SOX5,NEBL,ADCY2,PPP2R2B,NKAIN3,NRG3,LSAMP,ITPR2,GPC5,PTPRZ1,FMN2,RYR3,FBXL7
2.356e-07	-15.26	soft_tissue-blood_vessel-angiosarcoma	COSMIC cancer mutations	soft_tissue-blood_vessel-angiosarcoma	2192	21	16828	49	NKAIN3,PPP2R2B,NRG3,LSAMP,GPC5,ITPR2,FMN2,PTPRZ1,FBXL7,RYR3,CTNND2,SOX5,NEBL,ADCY2,SLC1A3,SLC1A2,PARD3,CDH20,MAML2,NTRK2,GPM6A
2.559e-07	-15.18	upper_aerodigestive_tract-mouth-carcinoma-squamous_cell_carcinoma	COSMIC cancer mutations	upper_aerodigestive_tract-mouth-carcinoma-squamous_cell_carcinoma	6953	38	16828	49	PPP2R2B,RFX4,FMN2,RYR3,ATP13A4,GPC5,NHSL1,ATP1A2,PITPNC1,NTM,TRPS1,PARD3,ZBTB20,MAML2,SORBS1,MACF1,GPM6A,FUT9,LSAMP,NRG3,CSGALNACT1,PTPRZ1,FBXL7,ITPR2,CTNND2,SOX5,SFXN5,ADCY2,NEBL,ABLIM1,SLC1A2,DTNA,PARD3B,TNIK,CDH20,SLC4A4,RORA,MGAT4C
2.608e-07	-15.16	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-diffuse_large_B_cell_lymphoma	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-diffuse_large_B_cell_lymphoma	3608	27	16828	49	MACF1,GPM6A,SPARCL1,MAML2,PARD3,AQP4,ATP1A2,FMN2,RYR3,ATP13A4,GPC5,PPP2R2B,TNIK,CDH20,RORA,SLC1A2,NEBL,ADCY2,CPE,CTNND2,SOX5,FBXL7,ITPR2,NRG3,LSAMP,CSGALNACT1,NKAIN3
2.732e-07	-15.11	blood_vessel	COSMIC cancer mutations	blood_vessel	2211	21	16828	49	ITPR2,GPC5,FBXL7,RYR3,PTPRZ1,FMN2,NKAIN3,PPP2R2B,NRG3,LSAMP,ADCY2,NEBL,SOX5,CTNND2,PARD3,CDH20,SLC1A2,SLC1A3,NTRK2,GPM6A,MAML2
4.615e-07	-14.59	nervous system development	biological process	GO:0007399	2185	20	18204	50	SLC1A3,FUT9,RORA,SLC1A2,BMPR1B,TNIK,MSI2,GPM6A,PARD3,RFX4,CTNND2,NTM,LSAMP,NFIA,NTRK2,ATP1A2,NRG3,SOX5,PTPRZ1,CTNNA2
5.321e-07	-14.45	MAPT (microtubule associated protein tau)	protein interactions	4137	948	13	19454	50	NEBL,TNIK,NTM,GPM6A,ABLIM1,CTNNA2,ATP1A2,PPP2R2B,SLC1A3,SLC1A2,CTNND2,SORBS1,LSAMP
6.811e-07	-14.20	myelodysplastic_syndrome	COSMIC cancer mutations	myelodysplastic_syndrome	1174	15	16828	49	NFIA,BMPR1B,SLC1A2,PARD3,TNIK,NTRK2,NKAIN3,LSAMP,NRG3,FBXL7,RYR3,ATP1A2,SOX5,NPAS3,ADCY2
6.811e-07	-14.20	haematopoietic_and_lymphoid_tissue-haematopoietic_neoplasm-myelodysplastic_syndrome	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue-haematopoietic_neoplasm-myelodysplastic_syndrome	1174	15	16828	49	ADCY2,ATP1A2,SOX5,NPAS3,RYR3,FBXL7,NKAIN3,LSAMP,NRG3,NTRK2,PARD3,TNIK,NFIA,BMPR1B,SLC1A2
1.715e-06	-13.28	plasma_cell_myeloma	COSMIC cancer mutations	plasma_cell_myeloma	1263	15	16828	49	MACF1,GPM6A,NTRK2,ABLIM1,TRPS1,NTM,TNIK,CTNND2,ADCY2,NEBL,NRG3,FUT9,FMN2,RYR3,ATP13A4
1.715e-06	-13.28	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-plasma_cell_myeloma	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-plasma_cell_myeloma	1263	15	16828	49	CTNND2,NEBL,ADCY2,NRG3,FUT9,RYR3,ATP13A4,FMN2,GPM6A,NTRK2,MACF1,ABLIM1,TNIK,NTM,TRPS1
1.742e-06	-13.26	pharynx	COSMIC cancer mutations	pharynx	2696	22	16828	49	MACF1,NTRK2,SORBS1,PITPNC1,ATP1A2,NHSL1,NPAS3,GPC5,RFX4,FMN2,ATP13A4,RYR3,SLC4A4,PARD3B,NFIA,SLC1A2,DTNA,SFXN5,CTNND2,PTPRZ1,FUT9,NRG3
1.771e-06	-13.24	generation of neurons	biological process	GO:0048699	1158	14	18204	50	BMPR1B,TNIK,PARD3,GPM6A,SLC1A3,FUT9,RORA,SOX5,PTPRZ1,NTRK2,CTNNA2,NTM,CTNND2,NFIA
2.277e-06	-12.99	bone-humerus-other-chondroblastoma	COSMIC cancer mutations	bone-humerus-other-chondroblastoma	301	8	16828	49	FMN2,GPC5,NKAIN3,PPP2R2B,GPM6A,ADCY2,SFXN5,SOX5
2.806e-06	-12.78	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-chronic_lymphocytic_leukaemia-small_lymphocytic_lymphoma	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-chronic_lymphocytic_leukaemia-small_lymphocytic_lymphoma	3511	25	16828	49	MGAT4C,DTNA,BMPR1B,SLC4A4,TNIK,PARD3B,CTNND2,CPE,ADCY2,FUT9,LSAMP,NRG3,FBXL7,PTPRZ1,NTRK2,MACF1,SLC1A3,PARD3,MSI2,NPAS3,PITPNC1,PPP2R2B,GPC5,RYR3,FMN2
2.806e-06	-12.78	chronic_lymphocytic_leukaemia-small_lymphocytic_lymphoma	COSMIC cancer mutations	chronic_lymphocytic_leukaemia-small_lymphocytic_lymphoma	3511	25	16828	49	SLC1A3,MSI2,PARD3,MACF1,NTRK2,PPP2R2B,FMN2,RYR3,GPC5,NPAS3,PITPNC1,DTNA,BMPR1B,PARD3B,TNIK,SLC4A4,MGAT4C,FUT9,LSAMP,NRG3,PTPRZ1,FBXL7,CPE,CTNND2,ADCY2
3.130e-06	-12.67	humerus	COSMIC cancer mutations	humerus	546	10	16828	49	SOX5,GPM6A,ADCY2,SFXN5,NEBL,NKAIN3,PPP2R2B,FMN2,PARD3B,GPC5
4.640e-06	-12.28	system development	biological process	GO:0048731	3533	24	18204	50	CPE,CTNND2,NTM,ATP1A2,SOX5,RORA,FUT9,PARD3,MSI2,CSGALNACT1,TNIK,NFIA,RFX4,LSAMP,CTNNA2,NTRK2,PTPRZ1,TRPS1,NEBL,NRG3,SLC1A3,GPM6A,SLC1A2,BMPR1B
4.805e-06	-12.25	neuron differentiation	biological process	GO:0030182	1081	13	18204	50	TNIK,BMPR1B,PARD3,GPM6A,FUT9,SLC1A3,RORA,PTPRZ1,NTRK2,CTNNA2,NTM,CTNND2,NFIA
6.532e-06	-11.94	lung-right_lower_lobe-carcinoma-adenocarcinoma	COSMIC cancer mutations	lung-right_lower_lobe-carcinoma-adenocarcinoma	5692	32	16828	49	MGAT4C,DTNA,CDH20,PARD3B,SLC4A4,SOX5,CTNND2,NEBL,ADCY2,FUT9,NRG3,LSAMP,NKAIN3,FBXL7,PTPRZ1,ITPR2,SORBS1,MAML2,GPM6A,NTRK2,MACF1,SLC1A3,NTM,PARD3,TRPS1,NPAS3,ATP1A2,PPP2R2B,RYR3,ATP13A4,FMN2,GPC5
6.532e-06	-11.94	right_lower_lobe	COSMIC cancer mutations	right_lower_lobe	5692	32	16828	49	PTPRZ1,FBXL7,ITPR2,LSAMP,FUT9,NRG3,NKAIN3,ADCY2,NEBL,CTNND2,SOX5,PARD3B,CDH20,SLC4A4,DTNA,MGAT4C,FMN2,ATP13A4,RYR3,GPC5,PPP2R2B,NPAS3,ATP1A2,NTM,TRPS1,PARD3,SLC1A3,MACF1,GPM6A,NTRK2,MAML2,SORBS1
7.125e-06	-11.85	Par3_HAL_N_term	pfam domains	PF12053	2	2	17795	48	PARD3B,PARD3
7.143e-06	-11.85	Par3/HAL_N	interpro domains	IPR021922	2	2	18521	50	PARD3,PARD3B
8.073e-06	-11.73	haematopoietic_and_lymphoid_tissue-lymph_node-lymphoid_neoplasm-mantle_cell_lymphoma	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue-lymph_node-lymphoid_neoplasm-mantle_cell_lymphoma	476	9	16828	49	ATP13A4,RYR3,GPC5,LSAMP,NRG3,GPM6A,SFXN5,MAML2,CTNND2
8.240e-06	-11.71	adherens junction	cellular component	GO:0005912	188	6	19108	49	PARD3,PARD3B,SORBS1,CTNND2,CTNNA2,CDH20
8.577e-06	-11.67	oesophagus-carcinoma	COSMIC cancer mutations	oesophagus-carcinoma	4269	27	16828	49	TNIK,CDH20,PARD3B,SLC4A4,NFIA,ADCY2,SOX5,CTNND2,FBXL7,PTPRZ1,ITPR2,NRG3,CSGALNACT1,GPM6A,NTRK2,MACF1,SORBS1,NTM,ZBTB20,PARD3,TRPS1,NHSL1,ATP13A4,RYR3,FMN2,RFX4,PPP2R2B
8.905e-06	-11.63	mouth	COSMIC cancer mutations	mouth	9004	41	16828	49	SLC1A3,NTM,PARD3,ZBTB20,TRPS1,SORBS1,MAML2,NTRK2,GPM6A,MACF1,PPP2R2B,ATP13A4,RYR3,RFX4,FMN2,GPC5,NPAS3,NHSL1,ATP1A2,PITPNC1,ABLIM1,SLC1A2,DTNA,CDH20,TNIK,PARD3B,RORA,SLC4A4,MGAT4C,LSAMP,NRG3,FUT9,CSGALNACT1,FBXL7,PTPRZ1,ITPR2,SOX5,CTNND2,ADCY2,SFXN5,NEBL
9.076e-06	-11.61	autonomic_ganglia	COSMIC cancer mutations	autonomic_ganglia	4005	26	16828	49	RYR3,FMN2,RFX4,ATP1A2,NHSL1,NPAS3,AQP4,PITPNC1,PARD3,TRPS1,MAML2,GPM6A,NTRK2,MACF1,FUT9,FBXL7,PTPRZ1,CTNND2,ADCY2,NEBL,SLC1A2,NFIA,SLC4A4,TNIK,PARD3B,GLIS3
9.205e-06	-11.60	neurogenesis	biological process	GO:0022008	1334	14	18204	50	FUT9,SLC1A3,RORA,TNIK,BMPR1B,GPM6A,PARD3,CTNND2,NTM,NFIA,NTRK2,PTPRZ1,SOX5,CTNNA2
9.729e-06	-11.54	multicellular organism development	biological process	GO:0007275	3957	25	18204	50	NFIA,LSAMP,RFX4,CTNNA2,NRG3,NEBL,PTPRZ1,TRPS1,NTRK2,SLC1A3,GPM6A,BMPR1B,SLC1A2,CPE,NTM,CTNND2,SOX5,ATP1A2,RORA,FUT9,PARD3,MSI2,CDH20,TNIK,CSGALNACT1
1.006e-05	-11.51	plasma membrane	cellular component	GO:0005886	5538	29	19108	49	CPE,MACF1,PTPRZ1,DTNA,ITPR2,LSAMP,NTRK2,PARD3,SLC1A3,CTNND2,NKAIN3,SORBS1,FMN2,RYR3,CDH20,ATP13A4,ATP1A2,BMPR1B,AQP4,CTNNA2,GPM6A,SLC1A2,ADCY2,NRG3,TNIK,NTM,GPC5,PARD3B,SLC4A4
1.071e-05	-11.44	lung-right_upper_lobe-carcinoma-adenocarcinoma	COSMIC cancer mutations	lung-right_upper_lobe-carcinoma-adenocarcinoma	10376	44	16828	49	CPE,SOX5,CTNND2,NEBL,ADCY2,NRG3,FUT9,NKAIN3,FBXL7,PTPRZ1,ITPR2,MGAT4C,ABLIM1,TNIK,CDH20,RORA,SLC4A4,ATP1A2,PITPNC1,RYR3,ATP13A4,FMN2,SORBS1,NTRK2,PARD3,TRPS1,SFXN5,LSAMP,CSGALNACT1,GLIS3,DTNA,SLC1A2,BMPR1B,NFIA,PARD3B,NPAS3,PPP2R2B,RFX4,GPC5,GPM6A,MACF1,SLC1A3,NTM,ZBTB20
1.071e-05	-11.44	right_upper_lobe	COSMIC cancer mutations	right_upper_lobe	10376	44	16828	49	SORBS1,NTRK2,TRPS1,PARD3,ATP1A2,PITPNC1,FMN2,ATP13A4,RYR3,MGAT4C,ABLIM1,SLC4A4,RORA,CDH20,TNIK,CTNND2,SOX5,CPE,ADCY2,NEBL,NKAIN3,NRG3,FUT9,ITPR2,PTPRZ1,FBXL7,MACF1,GPM6A,SLC1A3,ZBTB20,NTM,NPAS3,PPP2R2B,GPC5,RFX4,GLIS3,NFIA,SLC1A2,DTNA,BMPR1B,PARD3B,SFXN5,CSGALNACT1,LSAMP
1.144e-05	-11.38	soft_tissue	COSMIC cancer mutations	soft_tissue	5828	32	16828	49	SORBS1,MAML2,SPARCL1,MACF1,GPM6A,NTRK2,SLC1A3,TRPS1,PARD3,NPAS3,NHSL1,AQP4,PPP2R2B,GPC5,FMN2,RYR3,GLIS3,NFIA,SLC1A2,RORA,PARD3B,CDH20,CTNND2,SOX5,NEBL,ADCY2,NKAIN3,LSAMP,NRG3,ITPR2,PTPRZ1,FBXL7
1.167e-05	-11.36	oesophagus-carcinoma-squamous_cell_carcinoma	COSMIC cancer mutations	oesophagus-carcinoma-squamous_cell_carcinoma	6486	34	16828	49	CPE,SOX5,CTNND2,NEBL,ADCY2,SFXN5,NRG3,CSGALNACT1,FBXL7,PTPRZ1,ITPR2,MGAT4C,GLIS3,ABLIM1,BMPR1B,TNIK,PARD3B,SLC4A4,NPAS3,ATP1A2,AQP4,PITPNC1,ATP13A4,RYR3,FMN2,GPC5,MAML2,SORBS1,GPM6A,MACF1,SPARCL1,PARD3,ZBTB20,TRPS1
1.294e-05	-11.26	anatomical structure morphogenesis	biological process	GO:0009653	2225	18	18204	50	NEBL,NRG3,SOX5,PTPRZ1,NTRK2,CTNNA2,ABLIM1,CTNND2,CPE,NFIA,BMPR1B,CSGALNACT1,TNIK,GPM6A,CDH20,PARD3,SLC1A3,RORA
1.437e-05	-11.15	cell morphogenesis	biological process	GO:0000902	687	10	18204	50	BMPR1B,PTPRZ1,TNIK,CTNNA2,PARD3,CDH20,GPM6A,SLC1A3,CTNND2,NFIA
1.598e-05	-11.04	nodular	COSMIC cancer mutations	nodular	1515	15	16828	49	SPARCL1,NTRK2,MACF1,GLIS3,SLC4A4,CDH20,ABLIM1,NEBL,CTNND2,ATP1A2,NPAS3,CPE,ATP13A4,PTPRZ1,FMN2
1.707e-05	-10.98	cell periphery	cellular component	GO:0071944	6020	30	19108	49	GPC5,PARD3B,NTM,TNIK,SLC4A4,BMPR1B,ATP1A2,AQP4,RYR3,CDH20,ATP13A4,SLC1A2,ADCY2,NRG3,CTNNA2,GPM6A,NTRK2,PARD3,LSAMP,SORBS1,FMN2,SLC1A3,CTNND2,NKAIN3,CPE,SPARCL1,ITPR2,PTPRZ1,DTNA,MACF1
1.881e-05	-10.88	upper_aerodigestive_tract-larynx-carcinoma-squamous_cell_carcinoma	COSMIC cancer mutations	upper_aerodigestive_tract-larynx-carcinoma-squamous_cell_carcinoma	1946	17	16828	49	BMPR1B,SLC4A4,RORA,ZBTB20,PARD3B,TNIK,MGAT4C,MAML2,MACF1,GPM6A,CSGALNACT1,ITPR2,FMN2,RYR3,SOX5,NPAS3,NEBL
1.907e-05	-10.87	larynx	COSMIC cancer mutations	larynx	1948	17	16828	49	MGAT4C,MAML2,MACF1,GPM6A,BMPR1B,PARD3B,TNIK,SLC4A4,RORA,ZBTB20,NPAS3,SOX5,NEBL,CSGALNACT1,FMN2,RYR3,ITPR2
1.910e-05	-10.87	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm	7307	36	16828	49	CPE,SOX5,CTNND2,ADCY2,SFXN5,NEBL,NRG3,LSAMP,NKAIN3,CSGALNACT1,FBXL7,PTPRZ1,ITPR2,MGAT4C,GLIS3,ABLIM1,SLC1A2,BMPR1B,TNIK,CDH20,PARD3B,RORA,NHSL1,PPP2R2B,RYR3,ATP13A4,FMN2,RFX4,GPC5,MAML2,NTRK2,GPM6A,MACF1,SPARCL1,SLC1A3,PARD3
2.057e-05	-10.79	cell junction	cellular component	GO:0030054	2224	17	19108	49	TNIK,PARD3,PARD3B,NTRK2,CTNND2,SLC1A3,SORBS1,SPARCL1,NFIA,CDH20,ATP1A2,GPM6A,CTNNA2,PTPRZ1,NRG3,DTNA,SLC1A2
2.776e-05	-10.49	autonomic_ganglia-neuroblastoma	COSMIC cancer mutations	autonomic_ganglia-neuroblastoma	3970	25	16828	49	FMN2,RFX4,RYR3,NPAS3,ATP1A2,PITPNC1,AQP4,TRPS1,PARD3,MAML2,MACF1,GPM6A,NTRK2,FUT9,PTPRZ1,FBXL7,CTNND2,NEBL,ADCY2,NFIA,SLC1A2,PARD3B,TNIK,SLC4A4,GLIS3
2.789e-05	-10.49	neuroblastoma	COSMIC cancer mutations	neuroblastoma	3971	25	16828	49	NEBL,ADCY2,CTNND2,PTPRZ1,FBXL7,FUT9,GLIS3,SLC4A4,PARD3B,TNIK,NFIA,SLC1A2,PITPNC1,AQP4,ATP1A2,NPAS3,RFX4,FMN2,RYR3,MACF1,NTRK2,GPM6A,MAML2,TRPS1,PARD3
3.402e-05	-10.29	skin-face-carcinoma-squamous_cell_carcinoma	COSMIC cancer mutations	skin-face-carcinoma-squamous_cell_carcinoma	2036	17	16828	49	GPM6A,MACF1,MSI2,PARD3,RORA,TRPS1,ABLIM1,NEBL,AQP4,PTPRZ1,FMN2,ITPR2,GPC5,NRG3,LSAMP,CSGALNACT1,PPP2R2B
4.274e-05	-10.06	Astrocytic Glutamate-Glutamine Uptake And Metabolism	REACTOME pathways	R-HSA-210455	4	2	10285	28	SLC1A3,SLC1A2
4.274e-05	-10.06	Neurotransmitter uptake and Metabolism In Glial Cells	REACTOME pathways	R-HSA-112313	4	2	10285	28	SLC1A3,SLC1A2
4.392e-05	-10.03	cervix-carcinoma-squamous_cell_carcinoma	COSMIC cancer mutations	cervix-carcinoma-squamous_cell_carcinoma	11789	46	16828	49	ADCY2,NEBL,CPE,CTNND2,SOX5,PTPRZ1,FBXL7,ITPR2,FUT9,NRG3,MGAT4C,TNIK,CDH20,SLC4A4,RORA,ABLIM1,PITPNC1,ATP1A2,FMN2,ATP13A4,RYR3,NTRK2,SORBS1,TRPS1,PARD3,SFXN5,LSAMP,CSGALNACT1,GLIS3,PARD3B,NFIA,BMPR1B,DTNA,SLC1A2,NHSL1,NPAS3,RFX4,GPC5,PPP2R2B,MACF1,GPM6A,SPARCL1,MAML2,NTM,ZBTB20,SLC1A3
4.451e-05	-10.02	cervix	COSMIC cancer mutations	cervix	11793	46	16828	49	PITPNC1,ATP1A2,FMN2,ATP13A4,RYR3,NTRK2,SORBS1,TRPS1,PARD3,ADCY2,NEBL,CTNND2,SOX5,CPE,ITPR2,PTPRZ1,FBXL7,NRG3,FUT9,MGAT4C,SLC4A4,RORA,CDH20,TNIK,ABLIM1,NPAS3,NHSL1,GPC5,RFX4,PPP2R2B,SPARCL1,MACF1,GPM6A,MAML2,ZBTB20,NTM,SLC1A3,SFXN5,CSGALNACT1,LSAMP,GLIS3,PARD3B,NFIA,DTNA,BMPR1B,SLC1A2
4.464e-05	-10.02	anatomical structure development	biological process	GO:0048856	5207	28	18204	50	CTNNA2,SPARCL1,PTPRZ1,TRPS1,NRG3,NEBL,NTRK2,FMN2,NFIA,LSAMP,RFX4,ABLIM1,GPM6A,SLC1A2,BMPR1B,SLC1A3,SOX5,ATP1A2,CPE,NTM,CTNND2,PARD3,CDH20,MSI2,TNIK,CSGALNACT1,RORA,FUT9
4.623e-05	-9.98	SFN (stratifin)	protein interactions	2810	671	9	19454	50	FMN2,ABLIM1,NFIA,SORBS1,PPP2R2B,TNIK,PARD3B,MACF1,PARD3
4.861e-05	-9.93	trunk	COSMIC cancer mutations	trunk	3554	23	16828	49	TRPS1,PARD3,CDH20,SLC1A3,ABLIM1,SPARCL1,MACF1,NTRK2,GLIS3,MGAT4C,MAML2,PTPRZ1,RYR3,ATP13A4,PPP2R2B,LSAMP,NRG3,NEBL,CTNND2,ATP1A2,SOX5,CPE,NPAS3
5.783e-05	-9.76	skin-trunk-malignant_melanoma-nodular	COSMIC cancer mutations	skin-trunk-malignant_melanoma-nodular	1291	13	16828	49	CDH20,ABLIM1,MACF1,NTRK2,SPARCL1,GLIS3,PTPRZ1,ATP13A4,NEBL,CPE,NPAS3,ATP1A2,CTNND2
6.426e-05	-9.65	face	COSMIC cancer mutations	face	2139	17	16828	49	NEBL,AQP4,PPP2R2B,CSGALNACT1,NRG3,LSAMP,ITPR2,GPC5,FMN2,PTPRZ1,GPM6A,MACF1,ABLIM1,PARD3,RORA,TRPS1,MSI2
6.856e-05	-9.59	glutamate:sodium symporter activity	molecular function	GO:0015501	5	2	18094	48	SLC1A2,SLC1A3
6.856e-05	-9.59	high-affinity L-glutamate transmembrane transporter activity	molecular function	GO:0005314	5	2	18094	48	SLC1A2,SLC1A3
7.355e-05	-9.52	D-aspartate transmembrane transport	biological process	GO:0070777	5	2	18204	50	SLC1A3,SLC1A2
7.355e-05	-9.52	D-aspartate import across plasma membrane	biological process	GO:0070779	5	2	18204	50	SLC1A3,SLC1A2
7.513e-05	-9.50	neurotransmitter uptake	biological process	GO:0001504	30	3	18204	50	SLC1A3,ATP1A2,SLC1A2
7.937e-05	-9.44	prostate	COSMIC cancer mutations	prostate	13883	49	16828	49	PITPNC1,ATP1A2,RYR3,ATP13A4,FMN2,NTRK2,SORBS1,PARD3,TRPS1,NEBL,ADCY2,SOX5,CTNND2,CPE,ITPR2,FBXL7,PTPRZ1,NKAIN3,FUT9,NRG3,MGAT4C,RORA,SLC4A4,CDH20,TNIK,ABLIM1,AQP4,NHSL1,NPAS3,GPC5,RFX4,PPP2R2B,SPARCL1,GPM6A,MACF1,MAML2,ZBTB20,MSI2,NTM,SLC1A3,SFXN5,CSGALNACT1,LSAMP,GLIS3,PARD3B,DTNA,SLC1A2,BMPR1B,NFIA
8.255e-05	-9.40	NTM (neurotrimin)	protein interactions	50863	33	3	19454	50	GPM6A,NTM,LSAMP
8.981e-05	-9.32	developmental process	biological process	GO:0032502	5716	29	18204	50	NFIA,ABLIM1,RFX4,LSAMP,SPARCL1,CTNNA2,FMN2,NTRK2,NEBL,NRG3,PTPRZ1,TRPS1,SLC1A3,GPM6A,SLC1A2,BMPR1B,CPE,CTNND2,NTM,ATP1A2,SOX5,RORA,FUT9,NHSL1,CDH20,MSI2,PARD3,TNIK,CSGALNACT1
8.991e-05	-9.32	carcinoid-endocrine_tumour	COSMIC cancer mutations	carcinoid-endocrine_tumour	7752	36	16828	49	ITPR2,FBXL7,PTPRZ1,CSGALNACT1,NKAIN3,NRG3,LSAMP,ADCY2,NEBL,SFXN5,SOX5,CTNND2,CPE,RORA,SLC4A4,CDH20,TNIK,BMPR1B,SLC1A2,ABLIM1,GLIS3,GPC5,RYR3,ATP13A4,RFX4,FMN2,PPP2R2B,ATP1A2,NHSL1,PARD3,TRPS1,SLC1A3,NTRK2,GPM6A,MACF1,MAML2
9.059e-05	-9.31	vascular transport	biological process	GO:0010232	86	4	18204	50	SLC4A4,SLC1A3,ATP1A2,SLC1A2
9.059e-05	-9.31	transport across blood-brain barrier	biological process	GO:0150104	86	4	18204	50	SLC4A4,SLC1A2,ATP1A2,SLC1A3
9.194e-05	-9.29	cell junction organization	biological process	GO:0034330	532	8	18204	50	NFIA,CTNND2,PARD3,CDH20,GPM6A,SPARCL1,SORBS1,NRG3
9.559e-05	-9.26	neuron development	biological process	GO:0048666	859	10	18204	50	NTM,SLC1A3,CTNND2,CTNNA2,PARD3,GPM6A,PTPRZ1,BMPR1B,TNIK,NTRK2
9.591e-05	-9.25	Bile secretion	KEGG pathways	hsa04976	71	4	7161	25	SLC4A4,ATP1A2,AQP4,ADCY2
9.591e-05	-9.25	Bile secretion	KEGG pathways	ko04976	71	4	7161	25	AQP4,ADCY2,ATP1A2,SLC4A4
1.061e-04	-9.15	RYDR_ITPR	pfam domains	PF01365	6	2	17795	48	ITPR2,RYR3
1.061e-04	-9.15	RIH_assoc	pfam domains	PF08454	6	2	17795	48	RYR3,ITPR2
1.061e-04	-9.15	Ins145_P3_rec	pfam domains	PF08709	6	2	17795	48	RYR3,ITPR2
1.064e-04	-9.15	Ins145_P3_rcpt	interpro domains	IPR014821	6	2	18521	50	RYR3,ITPR2
1.064e-04	-9.15	Ryanodine_IP3_receptor	interpro domains	IPR015925	6	2	18521	50	ITPR2,RYR3
1.064e-04	-9.15	RIH_assoc-dom	interpro domains	IPR013662	6	2	18521	50	ITPR2,RYR3
1.064e-04	-9.15	RIH_dom	interpro domains	IPR000699	6	2	18521	50	ITPR2,RYR3
1.064e-04	-9.15	RyR/IP3R_RIH_dom_sf	interpro domains	IPR035910	6	2	18521	50	RYR3,ITPR2
1.101e-04	-9.11	D-amino acid transport	biological process	GO:0042940	6	2	18204	50	SLC1A2,SLC1A3
1.101e-04	-9.11	L-aspartate import across plasma membrane	biological process	GO:0140009	6	2	18204	50	SLC1A3,SLC1A2
1.225e-04	-9.01	IP3 receptor type 1 binding core, RIH domain	gene3d domains	1.25.10.30	6	2	14470	42	ITPR2,RYR3
1.367e-04	-8.90	follicular_lymphoma	COSMIC cancer mutations	follicular_lymphoma	1209	12	16828	49	TNIK,PARD3,RORA,SOX5,CTNND2,ADCY2,AQP4,NRG3,LSAMP,NKAIN3,GPC5,ITPR2
1.374e-04	-8.89	C11orf52 (chromosome 11 open reading frame 52)	protein interactions	91894	310	6	19454	50	DTNA,FMN2,ABLIM1,PARD3,MACF1,TNIK
1.378e-04	-8.89	monoatomic ion transmembrane transporter activity	molecular function	GO:0015075	752	9	18094	48	ATP13A4,SLC4A4,SLC1A3,GPM6A,ITPR2,ATP1A2,SFXN5,SLC1A2,RYR3
1.412e-04	-8.87	multicellular organismal process	biological process	GO:0032501	6177	30	18204	50	ATP1A2,SOX5,CTNND2,NTM,CPE,TNIK,CSGALNACT1,CDH20,MSI2,PARD3,FUT9,RYR3,RORA,NTRK2,PTPRZ1,TRPS1,NRG3,NEBL,CTNNA2,ABLIM1,RFX4,LSAMP,NFIA,SLC1A2,BMPR1B,GPM6A,AQP4,SLC1A3,SLC4A4,DTNA
1.483e-04	-8.82	SDF	pfam domains	PF00375	7	2	17795	48	SLC1A2,SLC1A3
1.487e-04	-8.81	Na-dicarboxylate_symporter_CS	interpro domains	IPR018107	7	2	18521	50	SLC1A2,SLC1A3
1.487e-04	-8.81	Na:dicarbo_symporter_sf	interpro domains	IPR036458	7	2	18521	50	SLC1A2,SLC1A3
1.487e-04	-8.81	Na-dicarboxylate_symporter	interpro domains	IPR001991	7	2	18521	50	SLC1A2,SLC1A3
1.490e-04	-8.81	FLOT1 (flotillin 1)	protein interactions	10211	453	7	19454	50	DTNA,FMN2,ABLIM1,SORBS1,SOX5,PARD3,MACF1
1.534e-04	-8.78	metal ion transmembrane transporter activity	molecular function	GO:0046873	442	7	18094	48	ATP1A2,SLC1A2,RYR3,SLC1A3,GPM6A,ITPR2,SLC4A4
1.662e-04	-8.70	cellular response to alkaloid	biological process	GO:0071312	39	3	18204	50	RYR3,SLC1A2,SLC1A3
1.711e-04	-8.67	Sodium:dicarboxylate symporter	gene3d domains	1.10.3860.10	7	2	14470	42	SLC1A3,SLC1A2
1.841e-04	-8.60	beta-catenin binding	molecular function	GO:0008013	107	4	18094	48	CTNND2,RORA,CTNNA2,CDH20
1.874e-04	-8.58	bone-tibia-other-chondroblastoma	COSMIC cancer mutations	bone-tibia-other-chondroblastoma	98	4	16828	49	GPM6A,LSAMP,CTNND2,NKAIN3
2.008e-04	-8.51	scalp	COSMIC cancer mutations	scalp	2110	16	16828	49	SORBS1,MACF1,NFIA,NTM,RORA,SLC4A4,TRPS1,SOX5,ATP1A2,NEBL,LSAMP,PPP2R2B,ATP13A4,FMN2,PTPRZ1,GPC5
2.276e-04	-8.39	monoatomic cation transmembrane transporter activity	molecular function	GO:0008324	630	8	18094	48	RYR3,ATP1A2,SLC1A2,ITPR2,GPM6A,SLC1A3,SLC4A4,ATP13A4
2.295e-04	-8.38	NA_DICARBOXYL_SYMP_1	prosite domains	PS00713	7	2	12186	41	SLC1A2,SLC1A3
2.295e-04	-8.38	NA_DICARBOXYL_SYMP_2	prosite domains	PS00714	7	2	12186	41	SLC1A2,SLC1A3
2.304e-04	-8.38	LSAMP (limbic system associated membrane protein)	protein interactions	4045	9	2	19454	50	NTM,LSAMP
2.304e-04	-8.38	NEGR1 (neuronal growth regulator 1)	protein interactions	257194	9	2	19454	50	NTM,LSAMP
2.412e-04	-8.33	Salivary secretion	KEGG pathways	ko04970	90	4	7161	25	ADCY2,RYR3,ATP1A2,ITPR2
2.412e-04	-8.33	Salivary secretion	KEGG pathways	hsa04970	90	4	7161	25	ATP1A2,RYR3,ADCY2,ITPR2
2.551e-04	-8.27	acidic amino acid transport	biological process	GO:0015800	45	3	18204	50	SLC1A2,SLC1A3,NTRK2
2.564e-04	-8.27	OCLN (occludin)	protein interactions	100506658	495	7	19454	50	DTNA,FMN2,ABLIM1,TNIK,MACF1,NTRK2,PARD3
2.586e-04	-8.26	cellular response to organic cyclic compound	biological process	GO:0071407	464	7	18204	50	RORA,RYR3,ITPR2,SLC1A2,SLC1A3,ADCY2,ATP1A2
2.614e-04	-8.25	transporter activity	molecular function	GO:0005215	1211	11	18094	48	SLC1A3,GPM6A,SFXN5,ATP1A2,SLC1A2,RYR3,AQP4,ITPR2,ATP13A4,PITPNC1,SLC4A4
2.680e-04	-8.22	haematopoietic_and_lymphoid_tissue-lymph_node-lymphoid_neoplasm-diffuse_large_B_cell_lymphoma	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue-lymph_node-lymphoid_neoplasm-diffuse_large_B_cell_lymphoma	748	9	16828	49	PARD3,TRPS1,ITPR2,DTNA,SLC1A3,NEBL,NTRK2,SOX5,CTNND2
2.955e-04	-8.13	prostate-carcinoma-adenocarcinoma	COSMIC cancer mutations	prostate-carcinoma-adenocarcinoma	12379	46	16828	49	MAML2,SPARCL1,MACF1,GPM6A,SLC1A3,ZBTB20,NTM,NHSL1,NPAS3,AQP4,PPP2R2B,GPC5,RFX4,GLIS3,NFIA,BMPR1B,SLC1A2,PARD3B,SFXN5,CSGALNACT1,LSAMP,SORBS1,NTRK2,TRPS1,PARD3,ATP1A2,PITPNC1,FMN2,RYR3,ATP13A4,MGAT4C,ABLIM1,RORA,TNIK,CDH20,CTNND2,SOX5,CPE,ADCY2,NEBL,NKAIN3,FUT9,NRG3,ITPR2,PTPRZ1,FBXL7
2.970e-04	-8.12	Pancreatic secretion	KEGG pathways	hsa04972	95	4	7161	25	ATP1A2,SLC4A4,ADCY2,ITPR2
2.970e-04	-8.12	Pancreatic secretion	KEGG pathways	ko04972	95	4	7161	25	ADCY2,ATP1A2,SLC4A4,ITPR2
3.003e-04	-8.11	monoatomic ion transmembrane transport	biological process	GO:0034220	804	9	18204	50	ATP1A2,SLC1A2,GPM6A,SFXN5,SLC1A3,ITPR2,ATP13A4,RYR3,SLC4A4
3.121e-04	-8.07	cell-cell junction	cellular component	GO:0005911	513	7	19108	49	PARD3B,PARD3,ATP1A2,CDH20,SORBS1,CTNND2,CTNNA2
3.155e-04	-8.06	plasma membrane region	cellular component	GO:0098590	1278	11	19108	49	SLC4A4,SLC1A2,SORBS1,MACF1,GPM6A,SLC1A3,ATP1A2,AQP4,PARD3B,TNIK,PARD3
3.162e-04	-8.06	EPB41L4A (erythrocyte membrane protein band 4.1 like 4A)	protein interactions	64097	127	4	19454	50	ABLIM1,DTNA,PARD3,MACF1
3.162e-04	-8.06	MIR	pfam domains	PF02815	10	2	17795	48	RYR3,ITPR2
3.165e-04	-8.06	central nervous system development	biological process	GO:0007417	995	10	18204	50	CTNNA2,MSI2,BMPR1B,PTPRZ1,SLC1A2,NRG3,NTRK2,ATP1A2,RORA,RFX4
3.170e-04	-8.06	MIR_motif	interpro domains	IPR016093	10	2	18521	50	ITPR2,RYR3
3.170e-04	-8.06	MIR_dom_sf	interpro domains	IPR036300	10	2	18521	50	RYR3,ITPR2
3.226e-04	-8.04	Transmembrane transport of small molecules	REACTOME pathways	R-HSA-382551	677	8	10285	28	ATP13A4,SLC1A2,ATP1A2,SLC1A3,AQP4,SLC4A4,ADCY2,RYR3
3.234e-04	-8.04	upper_aerodigestive_tract-mouth-carcinoma	COSMIC cancer mutations	upper_aerodigestive_tract-mouth-carcinoma	6426	31	16828	49	PPP2R2B,GPC5,RYR3,RFX4,FMN2,NHSL1,NPAS3,PITPNC1,SLC1A3,PARD3,ZBTB20,TRPS1,NTM,MAML2,SORBS1,GPM6A,MACF1,NRG3,FUT9,FBXL7,SOX5,CTNND2,ADCY2,SFXN5,SLC1A2,ABLIM1,RORA,SLC4A4,CDH20,PARD3B,MGAT4C
3.244e-04	-8.03	bone	COSMIC cancer mutations	bone	8157	36	16828	49	SFXN5,NEBL,ADCY2,CPE,CTNND2,SOX5,PTPRZ1,ITPR2,LSAMP,NRG3,CSGALNACT1,NKAIN3,GLIS3,PARD3B,TNIK,SLC4A4,RORA,ABLIM1,DTNA,NPAS3,ATP1A2,FMN2,RYR3,ATP13A4,GPC5,PPP2R2B,MACF1,GPM6A,NTRK2,SPARCL1,MAML2,SORBS1,TRPS1,PARD3,ZBTB20,SLC1A3
3.281e-04	-8.02	neuronal action potential propagation	biological process	GO:0019227	10	2	18204	50	ATP1A2,NTRK2
3.281e-04	-8.02	action potential propagation	biological process	GO:0098870	10	2	18204	50	ATP1A2,NTRK2
3.281e-04	-8.02	cellular response to cocaine	biological process	GO:0071314	10	2	18204	50	SLC1A3,SLC1A2
3.281e-04	-8.02	establishment of centrosome localization	biological process	GO:0051660	10	2	18204	50	PARD3B,PARD3
3.354e-04	-8.00	MARK3 (microtubule affinity regulating kinase 3)	protein interactions	4140	235	5	19454	50	NTRK2,PARD3,MACF1,PPP2R2B,DTNA
3.424e-04	-7.98	neuron projection morphogenesis	biological process	GO:0048812	486	7	18204	50	BMPR1B,PTPRZ1,TNIK,CTNNA2,GPM6A,PARD3,CTNND2
3.507e-04	-7.96	EDTRNSPORT	prints domains	PR00173	7	2	5227	22	SLC1A3,SLC1A2
3.642e-04	-7.92	plasma membrane bounded cell projection morphogenesis	biological process	GO:0120039	491	7	18204	50	PARD3,GPM6A,CTNNA2,TNIK,BMPR1B,PTPRZ1,CTNND2
3.870e-04	-7.86	cell projection morphogenesis	biological process	GO:0048858	496	7	18204	50	CTNND2,CTNNA2,GPM6A,PARD3,BMPR1B,PTPRZ1,TNIK
3.988e-04	-7.83	NTRK2 (neurotrophic receptor tyrosine kinase 2)	protein interactions	4915	135	4	19454	50	ABLIM1,PARD3,NTRK2,DTNA
4.003e-04	-7.82	L-aspartate transmembrane transport	biological process	GO:0070778	11	2	18204	50	SLC1A2,SLC1A3
4.003e-04	-7.82	L-glutamate import across plasma membrane	biological process	GO:0098712	11	2	18204	50	SLC1A3,SLC1A2
4.044e-04	-7.81	mucosal	COSMIC cancer mutations	mucosal	2009	15	16828	49	MGAT4C,SORBS1,SPARCL1,ABLIM1,BMPR1B,PARD3,RORA,CPE,ATP1A2,CTNND2,NEBL,NRG3,PPP2R2B,FMN2,ATP13A4
4.044e-04	-7.81	skin-mucosal-malignant_melanoma	COSMIC cancer mutations	skin-mucosal-malignant_melanoma	2009	15	16828	49	RORA,PARD3,ABLIM1,BMPR1B,SPARCL1,SORBS1,MGAT4C,ATP13A4,FMN2,NRG3,PPP2R2B,NEBL,CPE,ATP1A2,CTNND2
4.129e-04	-7.79	plasma membrane bounded cell projection	cellular component	GO:0120025	2285	15	19108	49	FMN2,CTNND2,SLC1A3,PARD3,ABLIM1,NTRK2,DTNA,SLC1A2,ADCY2,CTNNA2,GPM6A,MACF1,AQP4,ATP1A2,BMPR1B
4.146e-04	-7.79	regulation of chondrocyte differentiation	biological process	GO:0032330	53	3	18204	50	SOX5,BMPR1B,TRPS1
4.282e-04	-7.76	haematopoietic_and_lymphoid_tissue	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue	14368	49	16828	49	MGAT4C,RORA,SLC4A4,CDH20,TNIK,ABLIM1,ADCY2,NEBL,SOX5,CTNND2,CPE,ITPR2,FBXL7,PTPRZ1,NKAIN3,NRG3,FUT9,NTRK2,SORBS1,PARD3,TRPS1,PITPNC1,ATP1A2,ATP13A4,RYR3,FMN2,GLIS3,PARD3B,DTNA,BMPR1B,SLC1A2,NFIA,SFXN5,CSGALNACT1,LSAMP,SPARCL1,GPM6A,MACF1,MAML2,ZBTB20,MSI2,NTM,SLC1A3,AQP4,NPAS3,NHSL1,GPC5,RFX4,PPP2R2B
4.301e-04	-7.75	LYN (LYN proto-oncogene, Src family tyrosine kinase)	protein interactions	4067	713	8	19454	50	MSI2,MACF1,PARD3,TNIK,FMN2,ABLIM1,SLC1A3,DTNA
4.439e-04	-7.72	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-follicular_lymphoma	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-follicular_lymphoma	981	10	16828	49	NKAIN3,NRG3,LSAMP,PARD3,RORA,ITPR2,GPC5,SOX5,CTNND2,ADCY2
4.466e-04	-7.71	neuron projection	cellular component	GO:0043005	1331	11	19108	49	GPM6A,CTNNA2,SLC1A3,CTNND2,ADCY2,SLC1A2,DTNA,BMPR1B,ATP1A2,NTRK2,PARD3
4.548e-04	-7.70	Ion homeostasis	REACTOME pathways	R-HSA-5578775	56	3	10285	28	RYR3,ATP1A2,ITPR2
4.698e-04	-7.66	amino acid transport	biological process	GO:0006865	132	4	18204	50	SLC1A2,SLC1A3,NTRK2,SFXN5
4.778e-04	-7.65	sarcolemma	cellular component	GO:0042383	142	4	19108	49	RYR3,AQP4,DTNA,ATP1A2
4.806e-04	-7.64	stomach-carcinoma-intestinal_adenocarcinoma	COSMIC cancer mutations	stomach-carcinoma-intestinal_adenocarcinoma	7225	33	16828	49	RYR3,ATP13A4,FMN2,RFX4,NHSL1,NPAS3,ATP1A2,AQP4,PITPNC1,NTM,ZBTB20,PARD3,TRPS1,MAML2,NTRK2,MACF1,LSAMP,NRG3,CSGALNACT1,FBXL7,PTPRZ1,ITPR2,SOX5,CTNND2,SFXN5,NEBL,ADCY2,SLC1A2,NFIA,CDH20,PARD3B,RORA,SLC4A4
4.806e-04	-7.64	intestinal_adenocarcinoma	COSMIC cancer mutations	intestinal_adenocarcinoma	7225	33	16828	49	NHSL1,NPAS3,ATP1A2,AQP4,PITPNC1,ATP13A4,RYR3,RFX4,FMN2,MAML2,NTRK2,MACF1,NTM,ZBTB20,PARD3,TRPS1,SOX5,CTNND2,ADCY2,NEBL,SFXN5,NRG3,LSAMP,CSGALNACT1,FBXL7,PTPRZ1,ITPR2,SLC1A2,NFIA,CDH20,PARD3B,RORA,SLC4A4
4.886e-04	-7.62	MIR	prosite domains	PS50919	10	2	12186	41	RYR3,ITPR2
5.182e-04	-7.57	pancreas-carcinoid-endocrine_tumour	COSMIC cancer mutations	pancreas-carcinoid-endocrine_tumour	7250	33	16828	49	GLIS3,BMPR1B,SLC1A2,ABLIM1,RORA,SLC4A4,CDH20,SOX5,CTNND2,CPE,NEBL,ADCY2,SFXN5,CSGALNACT1,NKAIN3,LSAMP,NRG3,ITPR2,FBXL7,MAML2,NTRK2,GPM6A,MACF1,SLC1A3,PARD3,ATP1A2,NHSL1,PPP2R2B,GPC5,ATP13A4,RYR3,FMN2,RFX4
5.266e-04	-7.55	inorganic molecular entity transmembrane transporter activity	molecular function	GO:0015318	714	8	18094	48	ITPR2,GPM6A,SLC1A3,RYR3,ATP1A2,SLC1A2,AQP4,SLC4A4
5.570e-04	-7.49	MIR	smart domains	SM00472	10	2	9717	35	ITPR2,RYR3
5.584e-04	-7.49	transmembrane transporter activity	molecular function	GO:0022857	1110	10	18094	48	ATP13A4,AQP4,SLC4A4,ITPR2,GPM6A,SLC1A3,RYR3,SLC1A2,SFXN5,ATP1A2
5.953e-04	-7.43	Glutamatergic synapse	KEGG pathways	ko04724	114	4	7161	25	SLC1A2,ITPR2,SLC1A3,ADCY2
5.953e-04	-7.43	Glutamatergic synapse	KEGG pathways	hsa04724	114	4	7161	25	ADCY2,SLC1A3,ITPR2,SLC1A2
5.981e-04	-7.42	NAKATPASE	prints domains	PR00121	9	2	5227	22	ATP1A2,ATP13A4
6.145e-04	-7.39	L-glutamate transmembrane transporter activity	molecular function	GO:0005313	14	2	18094	48	SLC1A3,SLC1A2
6.239e-04	-7.38	upper_aerodigestive_tract-pharynx-carcinoma-nasopharyngeal_carcinoma	COSMIC cancer mutations	upper_aerodigestive_tract-pharynx-carcinoma-nasopharyngeal_carcinoma	1425	12	16828	49	ATP13A4,FMN2,RFX4,SFXN5,PITPNC1,CTNND2,ATP1A2,NHSL1,SLC4A4,SLC1A2,NFIA,NTRK2
6.239e-04	-7.38	nasopharyngeal_carcinoma	COSMIC cancer mutations	nasopharyngeal_carcinoma	1425	12	16828	49	ATP13A4,RFX4,FMN2,SLC4A4,SLC1A2,NFIA,NTRK2,SFXN5,PITPNC1,NHSL1,ATP1A2,CTNND2
6.388e-04	-7.36	CDH1 (cadherin 1)	protein interactions	999	757	8	19454	50	SORBS1,CTNND2,ABLIM1,CTNNA2,MACF1,NEBL,PARD3,NHSL1
6.588e-04	-7.33	sodium ion export across plasma membrane	biological process	GO:0036376	14	2	18204	50	SLC4A4,ATP1A2
6.654e-04	-7.32	TIAM2 (TIAM Rac1 associated GEF 2)	protein interactions	26230	15	2	19454	50	TNIK,PARD3
6.932e-04	-7.27	cell projection	cellular component	GO:0042995	2398	15	19108	49	ABLIM1,PARD3,NTRK2,CTNND2,SLC1A3,FMN2,AQP4,BMPR1B,ATP1A2,MACF1,CTNNA2,GPM6A,DTNA,SLC1A2,ADCY2
7.502e-04	-7.20	haematopoietic_and_lymphoid_tissue-haematopoietic_neoplasm-mast_cell_neoplasm	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue-haematopoietic_neoplasm-mast_cell_neoplasm	248	5	16828	49	NFIA,NPAS3,NRG3,ADCY2,GPC5
7.502e-04	-7.20	mast_cell_neoplasm	COSMIC cancer mutations	mast_cell_neoplasm	248	5	16828	49	GPC5,ADCY2,NRG3,NPAS3,NFIA
7.592e-04	-7.18	CNTNAP2 (contactin associated protein 2)	protein interactions	26047	16	2	19454	50	MACF1,CPE
7.721e-04	-7.17	active monoatomic ion transmembrane transporter activity	molecular function	GO:0022853	274	5	18094	48	ATP13A4,SLC1A3,ATP1A2,SLC4A4,SLC1A2
8.077e-04	-7.12	sodium ion transmembrane transporter activity	molecular function	GO:0015081	158	4	18094	48	ATP1A2,SLC1A2,SLC4A4,SLC1A3
8.086e-04	-7.12	human chr3q13.31	chromosome location	human chr3q13.31	22	2	26134	50	ZBTB20,LSAMP
8.309e-04	-7.09	PARD3 (par-3 family cell polarity regulator)	protein interactions	56288	287	5	19454	50	SORBS1,DTNA,NTRK2,PARD3,PARD3B
8.440e-04	-7.08	VASP (vasodilator stimulated phosphoprotein)	protein interactions	7408	288	5	19454	50	SORBS1,FMN2,PARD3,NEBL,NHSL1
8.632e-04	-7.05	inorganic cation transmembrane transporter activity	molecular function	GO:0022890	589	7	18094	48	RYR3,ATP1A2,SLC1A2,GPM6A,ITPR2,SLC1A3,SLC4A4
8.657e-04	-7.05	asymmetric cell division	biological process	GO:0008356	16	2	18204	50	SOX5,PARD3
8.795e-04	-7.04	retina development in camera-type eye	biological process	GO:0060041	156	4	18204	50	GPM6A,NFIA,BMPR1B,NTRK2
8.890e-04	-7.03	cellular response to endogenous stimulus	biological process	GO:0071495	1135	10	18204	50	NFIA,RYR3,SLC1A3,ITPR2,SORBS1,NTRK2,ATP1A2,SOX5,BMPR1B,SLC1A2
9.374e-04	-6.97	telencephalon development	biological process	GO:0021537	276	5	18204	50	RFX4,NTRK2,ATP1A2,SLC1A2,NRG3
9.444e-04	-6.96	cell adhesion	biological process	GO:0007155	942	9	18204	50	PARD3B,SPARCL1,PARD3,CDH20,CTNNA2,SORBS1,CTNND2,LSAMP,NTM
9.623e-04	-6.95	actin binding	molecular function	GO:0003779	434	6	18094	48	MACF1,SORBS1,CTNNA2,FMN2,NEBL,ABLIM1
9.873e-04	-6.92	intracellular chemical homeostasis	biological process	GO:0055082	581	7	18204	50	ATP13A4,ATP1A2,SLC1A3,ZBTB20,AQP4,RYR3,SLC4A4
1.022e-03	-6.89	Htt (huntingtin)	protein interactions	15194	77	3	19454	50	LSAMP,GPM6A,NTM
1.026e-03	-6.88	acidic amino acid transmembrane transporter activity	molecular function	GO:0015172	18	2	18094	48	SLC1A3,SLC1A2
1.026e-03	-6.88	intracellularly gated calcium channel activity	molecular function	GO:0015278	18	2	18094	48	RYR3,ITPR2
1.043e-03	-6.87	synapse	cellular component	GO:0045202	1473	11	19108	49	SLC1A2,DTNA,NRG3,PTPRZ1,GPM6A,ATP1A2,SPARCL1,SLC1A3,CTNND2,NTRK2,TNIK
1.059e-03	-6.85	regulation of cartilage development	biological process	GO:0061035	73	3	18204	50	TRPS1,BMPR1B,SOX5
1.060e-03	-6.85	Cation_ATPase_N	pfam domains	PF00690	18	2	17795	48	ATP13A4,ATP1A2
1.063e-03	-6.85	ATPase_P-typ_cation-transptr_N	interpro domains	IPR004014	18	2	18521	50	ATP1A2,ATP13A4
1.066e-03	-6.84	lung-left_upper_lobe-carcinoma-adenocarcinoma	COSMIC cancer mutations	lung-left_upper_lobe-carcinoma-adenocarcinoma	556	7	16828	49	RYR3,FBXL7,TRPS1,SLC4A4,NTRK2,ADCY2,CTNND2
1.071e-03	-6.84	astrocyte projection	cellular component	GO:0097449	19	2	19108	49	SLC1A2,AQP4
1.082e-03	-6.83	cell junction assembly	biological process	GO:0034329	285	5	18204	50	SORBS1,GPM6A,CDH20,PARD3,NRG3
1.089e-03	-6.82	left_upper_lobe	COSMIC cancer mutations	left_upper_lobe	558	7	16828	49	SLC4A4,TRPS1,RYR3,FBXL7,CTNND2,ADCY2,NTRK2
1.112e-03	-6.80	monoatomic ion transport	biological process	GO:0006811	964	9	18204	50	ATP1A2,SLC1A2,GPM6A,SFXN5,SLC1A3,ITPR2,ATP13A4,SLC4A4,RYR3
1.134e-03	-6.78	spleen	COSMIC cancer mutations	spleen	408	6	16828	49	SORBS1,ADCY2,TNIK,NTM,PTPRZ1,PARD3B
1.158e-03	-6.76	superficial_spreading	COSMIC cancer mutations	superficial_spreading	1110	10	16828	49	SORBS1,MGAT4C,CTNND2,MACF1,ADCY2,FUT9,PPP2R2B,ATP13A4,NTM,SLC4A4
1.165e-03	-6.76	lung-carcinoma-squamous_cell_carcinoma	COSMIC cancer mutations	lung-carcinoma-squamous_cell_carcinoma	14664	49	16828	49	CTNND2,SOX5,CPE,ADCY2,NEBL,NKAIN3,FUT9,NRG3,ITPR2,PTPRZ1,FBXL7,MGAT4C,ABLIM1,SLC4A4,RORA,CDH20,TNIK,ATP1A2,PITPNC1,FMN2,RYR3,ATP13A4,SORBS1,NTRK2,TRPS1,PARD3,SFXN5,CSGALNACT1,LSAMP,GLIS3,NFIA,BMPR1B,DTNA,SLC1A2,PARD3B,NHSL1,NPAS3,AQP4,PPP2R2B,GPC5,RFX4,MAML2,SPARCL1,MACF1,GPM6A,SLC1A3,ZBTB20,NTM,MSI2
1.179e-03	-6.74	RHOB (ras homolog family member B)	protein interactions	388	832	8	19454	50	DTNA,TNIK,SLC1A3,MACF1,PARD3,PARD3B,FMN2,ABLIM1
1.215e-03	-6.71	central_nervous_system-brain-primitive_neuroectodermal_tumour-medulloblastoma-large_cell	COSMIC cancer mutations	central_nervous_system-brain-primitive_neuroectodermal_tumour-medulloblastoma-large_cell	1117	10	16828	49	ADCY2,SOX5,GPC5,PARD3,FMN2,RYR3,ATP13A4,CDH20,SLC1A2,NRG3
1.226e-03	-6.70	GSC (goosecoid homeobox)	protein interactions	145258	82	3	19454	50	NFIA,SOX5,TRPS1
1.227e-03	-6.70	cartilage condensation	biological process	GO:0001502	19	2	18204	50	BMPR1B,SOX5
1.247e-03	-6.69	solute:sodium symporter activity	molecular function	GO:0015370	80	3	18094	48	SLC1A3,SLC1A2,SLC4A4
1.271e-03	-6.67	oesophagus-middle_third-carcinoma-squamous_cell_carcinoma	COSMIC cancer mutations	oesophagus-middle_third-carcinoma-squamous_cell_carcinoma	3531	20	16828	49	MAML2,SPARCL1,GPM6A,MACF1,ABLIM1,ZBTB20,PARD3,SLC4A4,TNIK,SOX5,CTNND2,ATP1A2,NHSL1,NEBL,ADCY2,NRG3,GPC5,RYR3,FMN2,PTPRZ1
1.281e-03	-6.66	middle_third	COSMIC cancer mutations	middle_third	3533	20	16828	49	GPC5,RYR3,FMN2,PTPRZ1,NRG3,ADCY2,NEBL,SOX5,ATP1A2,CTNND2,NHSL1,ZBTB20,PARD3,SLC4A4,TNIK,ABLIM1,SPARCL1,GPM6A,MACF1,MAML2
1.283e-03	-6.66	dicarboxylic acid transport	biological process	GO:0006835	78	3	18204	50	SLC1A2,NTRK2,SLC1A3
1.283e-03	-6.66	positive regulation of carbohydrate metabolic process	biological process	GO:0045913	78	3	18204	50	ZBTB20,SORBS1,SLC4A4
1.289e-03	-6.65	cell morphogenesis involved in neuron differentiation	biological process	GO:0048667	443	6	18204	50	PTPRZ1,BMPR1B,PARD3,CTNNA2,SLC1A3,CTNND2
1.290e-03	-6.65	cartilage development	biological process	GO:0051216	173	4	18204	50	NFIA,CSGALNACT1,BMPR1B,SOX5
1.318e-03	-6.63	TENM1 (teneurin transmembrane protein 1)	protein interactions	10178	21	2	19454	50	MACF1,SORBS1
1.361e-03	-6.60	positive regulation of chondrocyte differentiation	biological process	GO:0032332	20	2	18204	50	BMPR1B,SOX5
1.361e-03	-6.60	aspartate transmembrane transport	biological process	GO:0015810	20	2	18204	50	SLC1A2,SLC1A3
1.397e-03	-6.57	contractile actin filament bundle	cellular component	GO:0097517	86	3	19108	49	ABLIM1,SORBS1,NEBL
1.397e-03	-6.57	stress fiber	cellular component	GO:0001725	86	3	19108	49	NEBL,SORBS1,ABLIM1
1.465e-03	-6.53	Cation_ATPase_N	smart domains	SM00831	16	2	9717	35	ATP1A2,ATP13A4
1.502e-03	-6.50	positive regulation of nucleotide catabolic process	biological process	GO:0030813	21	2	18204	50	SLC4A4,ZBTB20
1.502e-03	-6.50	positive regulation of glycolytic process	biological process	GO:0045821	21	2	18204	50	SLC4A4,ZBTB20
1.502e-03	-6.50	positive regulation of purine nucleotide catabolic process	biological process	GO:0033123	21	2	18204	50	SLC4A4,ZBTB20
1.502e-03	-6.50	cell aggregation	biological process	GO:0098743	21	2	18204	50	SOX5,BMPR1B
1.563e-03	-6.46	haematopoietic_neoplasm	COSMIC cancer mutations	haematopoietic_neoplasm	11082	42	16828	49	PARD3,MSI2,NTM,SLC1A3,SPARCL1,NTRK2,MACF1,MAML2,GPC5,RYR3,ATP13A4,RFX4,FMN2,PPP2R2B,ATP1A2,NHSL1,NPAS3,RORA,SLC4A4,TNIK,CDH20,PARD3B,DTNA,BMPR1B,SLC1A2,NFIA,ABLIM1,GLIS3,ITPR2,FBXL7,PTPRZ1,CSGALNACT1,NKAIN3,LSAMP,NRG3,FUT9,SFXN5,ADCY2,NEBL,SOX5,CTNND2,CPE
1.587e-03	-6.45	regulation of carbohydrate metabolic process	biological process	GO:0006109	183	4	18204	50	SORBS1,RORA,SLC4A4,ZBTB20
1.649e-03	-6.41	intracellular sodium ion homeostasis	biological process	GO:0006883	22	2	18204	50	ATP1A2,SLC1A3
1.664e-03	-6.40	monoatomic cation transmembrane transport	biological process	GO:0098655	636	7	18204	50	ATP1A2,GPM6A,ITPR2,ATP13A4,SLC1A3,RYR3,SLC4A4
1.683e-03	-6.39	amino acid:sodium symporter activity	molecular function	GO:0005283	23	2	18094	48	SLC1A2,SLC1A3
1.695e-03	-6.38	actomyosin	cellular component	GO:0042641	92	3	19108	49	SORBS1,ABLIM1,NEBL
1.757e-03	-6.34	TIAM1 (TIAM Rac1 associated GEF 1)	protein interactions	7074	201	4	19454	50	RYR3,DTNA,PARD3,ATP1A2
1.781e-03	-6.33	ovary-carcinoma-serous_carcinoma	COSMIC cancer mutations	ovary-carcinoma-serous_carcinoma	10710	41	16828	49	CPE,CTNND2,SOX5,NEBL,SFXN5,ADCY2,NRG3,FUT9,LSAMP,CSGALNACT1,PTPRZ1,FBXL7,ITPR2,MGAT4C,GLIS3,SLC1A2,DTNA,BMPR1B,PARD3B,CDH20,TNIK,SLC4A4,RORA,NHSL1,NPAS3,ATP1A2,PPP2R2B,FMN2,RYR3,ATP13A4,GPC5,SORBS1,MAML2,MACF1,NTRK2,SLC1A3,MSI2,NTM,TRPS1,ZBTB20,PARD3
1.808e-03	-6.32	lung-carcinoma-small_cell_carcinoma	COSMIC cancer mutations	lung-carcinoma-small_cell_carcinoma	9908	39	16828	49	SORBS1,MAML2,SPARCL1,NTRK2,GPM6A,MACF1,PARD3,TRPS1,NTM,MSI2,ATP1A2,NPAS3,PITPNC1,PPP2R2B,GPC5,RYR3,ATP13A4,FMN2,RFX4,MGAT4C,BMPR1B,DTNA,NFIA,ABLIM1,RORA,SLC4A4,TNIK,CDH20,PARD3B,SOX5,CTNND2,CPE,NEBL,CSGALNACT1,NKAIN3,NRG3,ITPR2,FBXL7,PTPRZ1
1.826e-03	-6.31	oligodendroglioma_Grade_III	COSMIC cancer mutations	oligodendroglioma_Grade_III	303	5	16828	49	MACF1,PTPRZ1,MGAT4C,FUT9,GLIS3
1.830e-03	-6.30	Hippo signaling pathway	KEGG pathways	ko04390	154	4	7161	25	BMPR1B,CTNNA2,PPP2R2B,PARD3
1.830e-03	-6.30	Hippo signaling pathway	KEGG pathways	hsa04390	154	4	7161	25	BMPR1B,CTNNA2,PPP2R2B,PARD3
1.831e-03	-6.30	small_cell_carcinoma	COSMIC cancer mutations	small_cell_carcinoma	9913	39	16828	49	MACF1,NTRK2,GPM6A,SPARCL1,MAML2,SORBS1,MSI2,NTM,TRPS1,PARD3,PITPNC1,NPAS3,ATP1A2,RFX4,FMN2,ATP13A4,RYR3,GPC5,PPP2R2B,MGAT4C,PARD3B,CDH20,TNIK,SLC4A4,RORA,ABLIM1,NFIA,DTNA,BMPR1B,NEBL,CPE,CTNND2,SOX5,PTPRZ1,FBXL7,ITPR2,NRG3,CSGALNACT1,NKAIN3
1.832e-03	-6.30	P-type ion transporter activity	molecular function	GO:0015662	24	2	18094	48	ATP13A4,ATP1A2
1.832e-03	-6.30	P-type transmembrane transporter activity	molecular function	GO:0140358	24	2	18094	48	ATP1A2,ATP13A4
1.901e-03	-6.27	Glutamate Neurotransmitter Release Cycle	REACTOME pathways	R-HSA-210500	24	2	10285	28	SLC1A2,SLC1A3
1.913e-03	-6.26	Adherens junction	KEGG pathways	hsa04520	72	3	7161	25	SORBS1,CTNNA2,PARD3
1.913e-03	-6.26	Adherens junction	KEGG pathways	ko04520	72	3	7161	25	PARD3,CTNNA2,SORBS1
1.913e-03	-6.26	human chr3q26.2-q26.31	chromosome location	human chr3q26.2-q26.31	1	1	26134	50	TNIK
1.913e-03	-6.26	human chr15q13.3-q14	chromosome location	human chr15q13.3-q14	1	1	26134	50	RYR3
1.913e-03	-6.26	human chr10p11.22-p11.21	chromosome location	human chr10p11.22-p11.21	1	1	26134	50	PARD3
1.913e-03	-6.26	human chr12q21.31-q21.32	chromosome location	human chr12q21.31-q21.32	1	1	26134	50	MGAT4C
1.915e-03	-6.26	actin filament bundle	cellular component	GO:0032432	96	3	19108	49	NEBL,ABLIM1,SORBS1
1.920e-03	-6.26	urinary_tract-bladder-carcinoma-transitional_cell_carcinoma	COSMIC cancer mutations	urinary_tract-bladder-carcinoma-transitional_cell_carcinoma	6040	28	16828	49	GLIS3,MGAT4C,NFIA,DTNA,ABLIM1,SLC4A4,PARD3B,CDH20,SFXN5,ADCY2,NEBL,NRG3,ITPR2,PTPRZ1,SORBS1,SPARCL1,MACF1,GPM6A,NTRK2,SLC1A3,TRPS1,PARD3,ZBTB20,ATP1A2,GPC5,RFX4,FMN2,ATP13A4
1.931e-03	-6.25	transitional_cell_carcinoma	COSMIC cancer mutations	transitional_cell_carcinoma	6042	28	16828	49	GLIS3,MGAT4C,SLC4A4,PARD3B,CDH20,NFIA,DTNA,ABLIM1,ADCY2,SFXN5,NEBL,ITPR2,PTPRZ1,NRG3,SPARCL1,MACF1,GPM6A,NTRK2,SORBS1,TRPS1,PARD3,ZBTB20,SLC1A3,ATP1A2,GPC5,RFX4,FMN2,ATP13A4
2.005e-03	-6.21	transmembrane transport	biological process	GO:0055085	1264	10	18204	50	AQP4,SFXN5,GPM6A,SLC1A2,ATP1A2,RYR3,SLC4A4,ITPR2,ATP13A4,SLC1A3
2.045e-03	-6.19	actin cytoskeleton	cellular component	GO:0015629	520	6	19108	49	SORBS1,ABLIM1,FMN2,MACF1,CTNNA2,NEBL
2.047e-03	-6.19	FRS2 (fibroblast growth factor receptor substrate 2)	protein interactions	10818	98	3	19454	50	PARD3,NTRK2,SORBS1
2.069e-03	-6.18	Thyroid hormone synthesis	KEGG pathways	hsa04918	74	3	7161	25	ITPR2,ATP1A2,ADCY2
2.069e-03	-6.18	Thyroid hormone synthesis	KEGG pathways	ko04918	74	3	7161	25	ADCY2,ATP1A2,ITPR2
2.118e-03	-6.16	Muscle contraction	REACTOME pathways	R-HSA-397014	204	4	10285	28	SORBS1,RYR3,ATP1A2,ITPR2
2.130e-03	-6.15	L-glutamate transmembrane transport	biological process	GO:0015813	25	2	18204	50	SLC1A3,SLC1A2
2.146e-03	-6.14	synapse organization	biological process	GO:0050808	333	5	18204	50	GPM6A,NFIA,SPARCL1,CTNND2,NRG3
2.151e-03	-6.14	Gastric acid secretion	KEGG pathways	ko04971	75	3	7161	25	ATP1A2,ADCY2,ITPR2
2.151e-03	-6.14	Gastric acid secretion	KEGG pathways	hsa04971	75	3	7161	25	ADCY2,ATP1A2,ITPR2
2.152e-03	-6.14	extrinsic component of plasma membrane	cellular component	GO:0019897	100	3	19108	49	CDH20,CTNNA2,DTNA
2.170e-03	-6.13	cell development	biological process	GO:0048468	2236	14	18204	50	SLC1A3,RORA,TNIK,BMPR1B,PARD3,GPM6A,MSI2,NTM,CTNND2,PTPRZ1,NEBL,NTRK2,FMN2,CTNNA2
2.178e-03	-6.13	CXADR (CXADR Ig-like cell adhesion molecule)	protein interactions	1525	357	5	19454	50	SORBS1,TNIK,MACF1,PARD3,NEBL
2.181e-03	-6.13	KCNJ12 (potassium inwardly rectifying channel subfamily J member 12)	protein interactions	3768	27	2	19454	50	ABLIM1,DTNA
2.181e-03	-6.13	HPCAL4 (hippocalcin like 4)	protein interactions	51440	27	2	19454	50	GPM6A,AQP4
2.200e-03	-6.12	EZR (ezrin)	protein interactions	7430	526	6	19454	50	SORBS1,ABLIM1,NEBL,MACF1,TNIK,DTNA
2.226e-03	-6.11	membrane	cellular component	GO:0016020	9220	34	19108	49	ATP1A2,BMPR1B,AQP4,RYR3,CDH20,ATP13A4,SLC1A2,ADCY2,NRG3,GPM6A,CTNNA2,MGAT4C,NTM,TNIK,PARD3B,GPC5,SLC4A4,PPP2R2B,CPE,DTNA,PTPRZ1,ITPR2,MACF1,NTRK2,FUT9,PARD3,CSGALNACT1,SFXN5,LSAMP,SORBS1,FMN2,SLC1A3,CTNND2,NKAIN3
2.261e-03	-6.09	skin-scalp-malignant_melanoma	COSMIC cancer mutations	skin-scalp-malignant_melanoma	634	7	16828	49	SORBS1,NEBL,PPP2R2B,NFIA,PTPRZ1,FMN2,NTM
2.304e-03	-6.07	C4-dicarboxylate transport	biological process	GO:0015740	26	2	18204	50	SLC1A3,SLC1A2
2.319e-03	-6.07	CTNNB1 (catenin beta 1)	protein interactions	1499	926	8	19454	50	CTNNA2,CTNND2,SORBS1,DTNA,NHSL1,PTPRZ1,PARD3,PARD3B
2.341e-03	-6.06	actin filament binding	molecular function	GO:0051015	211	4	18094	48	MACF1,CTNNA2,NEBL,ABLIM1
2.362e-03	-6.05	skin-head_neck-carcinoma-squamous_cell_carcinoma	COSMIC cancer mutations	skin-head_neck-carcinoma-squamous_cell_carcinoma	14191	48	16828	49	CTNND2,SOX5,CPE,NEBL,ADCY2,NKAIN3,NRG3,FUT9,ITPR2,PTPRZ1,FBXL7,MGAT4C,ABLIM1,SLC4A4,RORA,CDH20,TNIK,ATP1A2,PITPNC1,FMN2,RYR3,ATP13A4,SORBS1,NTRK2,TRPS1,PARD3,SFXN5,CSGALNACT1,LSAMP,GLIS3,NFIA,DTNA,SLC1A2,BMPR1B,PARD3B,NHSL1,NPAS3,AQP4,PPP2R2B,GPC5,RFX4,MAML2,SPARCL1,MACF1,GPM6A,SLC1A3,ZBTB20,NTM
2.365e-03	-6.05	Calcium-transporting ATPase, transmembrane domain	gene3d domains	1.20.1110.10	25	2	14470	42	ATP1A2,ATP13A4
2.412e-03	-6.03	haematopoietic_and_lymphoid_tissue-spleen-lymphoid_neoplasm-marginal_zone_lymphoma	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue-spleen-lymphoid_neoplasm-marginal_zone_lymphoma	323	5	16828	49	PTPRZ1,NTM,PARD3B,ADCY2,SORBS1
2.424e-03	-6.02	HUNK (hormonally up-regulated Neu-associated kinase)	protein interactions	30811	104	3	19454	50	SPARCL1,ABLIM1,SORBS1
2.504e-03	-5.99	skin-trunk-malignant_melanoma	COSMIC cancer mutations	skin-trunk-malignant_melanoma	2647	16	16828	49	PTPRZ1,ATP13A4,RYR3,PPP2R2B,NRG3,LSAMP,NEBL,CTNND2,ATP1A2,SOX5,TRPS1,PARD3,CDH20,SLC1A3,MGAT4C,MAML2
2.514e-03	-5.99	INSC (INSC spindle orientation adaptor protein)	protein interactions	387755	29	2	19454	50	PARD3,PARD3B
2.570e-03	-5.96	1700006A11Rik (RIKEN cDNA 1700006A11 gene)	protein interactions	71824	1	1	19454	50	BMPR1B
2.570e-03	-5.96	Dynlt1 (dynein light chain Tctex-type 1)	protein interactions	83462	1	1	19454	50	NTRK2
2.570e-03	-5.96	Isl1 (ISL1 transcription factor, LIM/homeodomain)	protein interactions	16392	1	1	19454	50	GLIS3
2.570e-03	-5.96	Hipk3 (homeodomain interacting protein kinase 3)	protein interactions	15259	1	1	19454	50	GLIS3
2.570e-03	-5.96	Dcaf7 (DDB1 and CUL4 associated factor 7)	protein interactions	71833	1	1	19454	50	BMPR1B
2.570e-03	-5.96	Lztr1 (leucine-zipper-like transcriptional regulator, 1)	protein interactions	66863	1	1	19454	50	BMPR1B
2.570e-03	-5.96	Bdnf (brain derived neurotrophic factor)	protein interactions	12064	1	1	19454	50	NTRK2
2.570e-03	-5.96	Agtrap (angiotensin II, type I receptor-associated protein)	protein interactions	11610	1	1	19454	50	PITPNC1
2.614e-03	-5.95	response to alkaloid	biological process	GO:0043279	100	3	18204	50	SLC1A3,SLC1A2,RYR3
2.615e-03	-5.95	cellular homeostasis	biological process	GO:0019725	689	7	18204	50	SLC4A4,RYR3,SLC1A3,ZBTB20,ATP13A4,AQP4,ATP1A2
2.645e-03	-5.94	tibia	COSMIC cancer mutations	tibia	836	8	16828	49	GPM6A,MACF1,CTNND2,CPE,TNIK,NKAIN3,ABLIM1,LSAMP
2.653e-03	-5.93	brain-derived neurotrophic factor receptor activity	molecular function	GO:0060175	1	1	18094	48	NTRK2
2.653e-03	-5.93	peptidoglycan glycosyltransferase activity	molecular function	GO:0008955	1	1	18094	48	CSGALNACT1
2.673e-03	-5.92	amino acid:monoatomic cation symporter activity	molecular function	GO:0005416	29	2	18094	48	SLC1A3,SLC1A2
2.673e-03	-5.92	ligand-gated calcium channel activity	molecular function	GO:0099604	29	2	18094	48	ITPR2,RYR3
2.681e-03	-5.92	marginal_zone_lymphoma	COSMIC cancer mutations	marginal_zone_lymphoma	331	5	16828	49	SORBS1,PTPRZ1,NTM,PARD3B,ADCY2
2.697e-03	-5.92	MAML2_TAD	pfam domains	PF20804	1	1	17795	48	MAML2
2.700e-03	-5.91	MAML2_TAD	interpro domains	IPR048452	1	1	18521	50	MAML2
2.700e-03	-5.91	SORBS1_SH3	interpro domains	IPR035606	1	1	18521	50	SORBS1
2.700e-03	-5.91	NTRK2	interpro domains	IPR020455	1	1	18521	50	NTRK2
2.700e-03	-5.91	SORBS1_SH3_2	interpro domains	IPR035611	1	1	18521	50	SORBS1
2.700e-03	-5.91	Nebulette_SH3	interpro domains	IPR035631	1	1	18521	50	NEBL
2.700e-03	-5.91	TRPS1	interpro domains	IPR028440	1	1	18521	50	TRPS1
2.700e-03	-5.91	SPARC-like_p1	interpro domains	IPR016359	1	1	18521	50	SPARCL1
2.700e-03	-5.91	M14_CPE_CPD	interpro domains	IPR034232	1	1	18521	50	CPE
2.700e-03	-5.91	SORBS1_SH3_1	interpro domains	IPR035610	1	1	18521	50	SORBS1
2.701e-03	-5.91	neuron projection development	biological process	GO:0031175	693	7	18204	50	BMPR1B,TNIK,PTPRZ1,GPM6A,PARD3,CTNNA2,CTNND2
2.709e-03	-5.91	large_intestine-caecum-carcinoma-adenocarcinoma	COSMIC cancer mutations	large_intestine-caecum-carcinoma-adenocarcinoma	14236	48	16828	49	SOX5,CTNND2,CPE,NEBL,ADCY2,NKAIN3,FUT9,NRG3,ITPR2,FBXL7,PTPRZ1,MGAT4C,ABLIM1,RORA,SLC4A4,TNIK,CDH20,ATP1A2,PITPNC1,ATP13A4,RYR3,FMN2,SORBS1,NTRK2,PARD3,TRPS1,SFXN5,CSGALNACT1,LSAMP,GLIS3,BMPR1B,SLC1A2,DTNA,NFIA,PARD3B,NHSL1,NPAS3,AQP4,PPP2R2B,GPC5,RFX4,MAML2,SPARCL1,GPM6A,MACF1,SLC1A3,ZBTB20,NTM
2.718e-03	-5.91	NR3C1 (nuclear receptor subfamily 3 group C member 1)	protein interactions	2908	950	8	19454	50	PPP2R2B,SLC1A3,TRPS1,CTNND2,NFIA,ADCY2,ZBTB20,ATP13A4
2.747e-03	-5.90	negative regulation of calcium:sodium antiporter activity	biological process	GO:1903280	1	1	18204	50	ATP1A2
2.747e-03	-5.90	olfactory cortex development	biological process	GO:0021989	1	1	18204	50	ATP1A2
2.747e-03	-5.90	directional guidance of interneurons involved in migration from the subpallium to the cortex	biological process	GO:0021840	1	1	18204	50	NRG3
2.747e-03	-5.90	Lewis x epitope biosynthetic process	biological process	GO:0106402	1	1	18204	50	FUT9
2.747e-03	-5.90	chemorepulsion involved in interneuron migration from the subpallium to the cortex	biological process	GO:0021842	1	1	18204	50	NRG3
2.747e-03	-5.90	trans-synaptic signaling by neuropeptide, modulating synaptic transmission	biological process	GO:0099551	1	1	18204	50	NTRK2
2.747e-03	-5.90	homologous chromosome movement towards spindle pole in meiosis I anaphase	biological process	GO:0051758	1	1	18204	50	FMN2
2.747e-03	-5.90	trans-synaptic signaling by neuropeptide	biological process	GO:0099540	1	1	18204	50	NTRK2
2.760e-03	-5.89	Sudden Infant Death Syndrome (SIDS) Susceptibility Pathways	WikiPathways	WP706	162	4	5310	20	RORA,SLC1A3,NTRK2,AQP4
2.781e-03	-5.89	cell division	biological process	GO:0051301	516	6	18204	50	PARD3,PARD3B,SOX5,FUT9,FMN2,FBXL7
2.809e-03	-5.87	caecum	COSMIC cancer mutations	caecum	14248	48	16828	49	GLIS3,PARD3B,BMPR1B,DTNA,SLC1A2,NFIA,SFXN5,CSGALNACT1,LSAMP,SPARCL1,GPM6A,MACF1,MAML2,ZBTB20,NTM,SLC1A3,AQP4,NPAS3,NHSL1,GPC5,RFX4,PPP2R2B,MGAT4C,RORA,SLC4A4,TNIK,CDH20,ABLIM1,NEBL,ADCY2,SOX5,CTNND2,CPE,ITPR2,FBXL7,PTPRZ1,NKAIN3,NRG3,FUT9,NTRK2,SORBS1,PARD3,TRPS1,PITPNC1,ATP1A2,RYR3,ATP13A4,FMN2
2.830e-03	-5.87	Proximal tubule bicarbonate reclamation	KEGG pathways	ko04964	23	2	7161	25	SLC4A4,ATP1A2
2.830e-03	-5.87	Proximal tubule bicarbonate reclamation	KEGG pathways	hsa04964	23	2	7161	25	SLC4A4,ATP1A2
2.857e-03	-5.86	cell body	cellular component	GO:0044297	556	6	19108	49	ATP1A2,BMPR1B,SLC1A2,CTNND2,SLC1A3,GPM6A
2.857e-03	-5.86	catenin complex	cellular component	GO:0016342	31	2	19108	49	CTNNA2,CDH20
2.862e-03	-5.86	ACTB (actin beta)	protein interactions	60	958	8	19454	50	MACF1,NEBL,NHSL1,SORBS1,FMN2,ABLIM1,SFXN5,DTNA
2.863e-03	-5.86	peripheral nervous system axon ensheathment	biological process	GO:0032292	29	2	18204	50	NTRK2,PARD3
2.863e-03	-5.86	myelination in peripheral nervous system	biological process	GO:0022011	29	2	18204	50	NTRK2,PARD3
2.863e-03	-5.86	DST (dystonin)	protein interactions	667	230	4	19454	50	TNIK,NTRK2,PARD3,ATP1A2
2.968e-03	-5.82	Transport of inorganic cations/anions and amino acids/oligopeptides	REACTOME pathways	R-HSA-425393	107	3	10285	28	SLC1A2,SLC1A3,SLC4A4
2.991e-03	-5.81	TBR1 (T-box brain transcription factor 1)	protein interactions	10716	112	3	19454	50	TRPS1,SOX5,NFIA
3.002e-03	-5.81	neural precursor cell proliferation	biological process	GO:0061351	105	3	18204	50	RORA,NFIA,SOX5
3.044e-03	-5.79	glial cell differentiation	biological process	GO:0010001	219	4	18204	50	NTRK2,PTPRZ1,NFIA,PARD3
3.051e-03	-5.79	intracellularly ligand-gated monoatomic ion channel activity	molecular function	GO:0005217	31	2	18094	48	RYR3,ITPR2
3.057e-03	-5.79	DSG3 (desmoglein 3)	protein interactions	1830	32	2	19454	50	CSGALNACT1,PPP2R2B
3.062e-03	-5.79	L-glutamate import	biological process	GO:0051938	30	2	18204	50	SLC1A3,SLC1A2
3.072e-03	-5.79	upper_aerodigestive_tract-pharynx-carcinoma-squamous_cell_carcinoma	COSMIC cancer mutations	upper_aerodigestive_tract-pharynx-carcinoma-squamous_cell_carcinoma	1485	11	16828	49	SORBS1,MACF1,DTNA,PARD3B,NPAS3,FUT9,NRG3,GPC5,RYR3,PTPRZ1,FMN2
3.104e-03	-5.78	upper_aerodigestive_tract	COSMIC cancer mutations	upper_aerodigestive_tract	13181	46	16828	49	SLC4A4,RORA,TNIK,CDH20,ABLIM1,MGAT4C,ITPR2,PTPRZ1,FBXL7,NKAIN3,NRG3,FUT9,ADCY2,NEBL,CTNND2,SOX5,TRPS1,PARD3,NTRK2,SORBS1,FMN2,ATP13A4,RYR3,PITPNC1,ATP1A2,PARD3B,NFIA,DTNA,BMPR1B,SLC1A2,GLIS3,CSGALNACT1,LSAMP,SFXN5,ZBTB20,MSI2,NTM,SLC1A3,MACF1,GPM6A,MAML2,GPC5,RFX4,PPP2R2B,NHSL1,NPAS3
3.152e-03	-5.76	E1-E2_ATPase	pfam domains	PF00122	31	2	17795	48	ATP13A4,ATP1A2
3.221e-03	-5.74	chemical homeostasis	biological process	GO:0048878	914	8	18204	50	SLC4A4,RORA,RYR3,ZBTB20,SLC1A3,ATP13A4,AQP4,ATP1A2
3.222e-03	-5.74	SMAD7 (SMAD family member 7)	protein interactions	4092	115	3	19454	50	BMPR1B,SOX5,PARD3
3.356e-03	-5.70	Cation_ATPase	pfam domains	PF13246	32	2	17795	48	ATP13A4,ATP1A2
3.383e-03	-5.69	stomach-adenocarcinoma	COSMIC cancer mutations	stomach-adenocarcinoma	4101	21	16828	49	NEBL,CTNND2,ATP1A2,FMN2,RFX4,ATP13A4,GPC5,ITPR2,NRG3,CSGALNACT1,PPP2R2B,MACF1,MGAT4C,PARD3B,CDH20,SLC4A4,TRPS1,PARD3,RORA,ABLIM1,SLC1A2
3.445e-03	-5.67	brain development	biological process	GO:0007420	724	7	18204	50	RORA,CTNNA2,RFX4,ATP1A2,NTRK2,SLC1A2,NRG3
3.479e-03	-5.66	microtubule organizing center localization	biological process	GO:0061842	32	2	18204	50	PARD3B,PARD3
3.479e-03	-5.66	transepithelial transport	biological process	GO:0070633	32	2	18204	50	SLC1A2,SLC1A3
3.479e-03	-5.66	positive regulation of cartilage development	biological process	GO:0061036	32	2	18204	50	BMPR1B,SOX5
3.479e-03	-5.66	positive regulation of ATP metabolic process	biological process	GO:1903580	32	2	18204	50	ZBTB20,SLC4A4
3.479e-03	-5.66	centrosome localization	biological process	GO:0051642	32	2	18204	50	PARD3,PARD3B
3.482e-03	-5.66	cell adhesion molecule binding	molecular function	GO:0050839	560	6	18094	48	CPE,MACF1,CTNND2,CTNNA2,PTPRZ1,CDH20
3.531e-03	-5.65	central_nervous_system-cerebellum-glioma-astrocytoma_Grade_I	COSMIC cancer mutations	central_nervous_system-cerebellum-glioma-astrocytoma_Grade_I	105	3	16828	49	NRG3,GPC5,PARD3
3.602e-03	-5.63	DELLA	smart domains	SM01129	1	1	9717	35	MACF1
3.621e-03	-5.62	serous_carcinoma	COSMIC cancer mutations	serous_carcinoma	10987	41	16828	49	NTRK2,MACF1,MAML2,SORBS1,PARD3,ZBTB20,TRPS1,NTM,MSI2,SLC1A3,ATP1A2,NHSL1,NPAS3,GPC5,ATP13A4,RYR3,FMN2,PPP2R2B,GLIS3,MGAT4C,RORA,SLC4A4,CDH20,TNIK,PARD3B,DTNA,SLC1A2,BMPR1B,ADCY2,NEBL,SFXN5,SOX5,CTNND2,CPE,ITPR2,FBXL7,PTPRZ1,CSGALNACT1,FUT9,NRG3,LSAMP
3.649e-03	-5.61	TPRA1 (transmembrane protein adipocyte associated 1)	protein interactions	131601	35	2	19454	50	ITPR2,BMPR1B
3.656e-03	-5.61	thyroid-carcinoma	COSMIC cancer mutations	thyroid-carcinoma	4126	21	16828	49	NFIA,DTNA,TRPS1,PARD3,TNIK,GLIS3,SPARCL1,MACF1,FUT9,LSAMP,GPC5,ITPR2,PTPRZ1,ATP13A4,RYR3,CTNND2,ATP1A2,SOX5,CPE,ADCY2,AQP4
3.688e-03	-5.60	calcium channel activity	molecular function	GO:0005262	117	3	18094	48	RYR3,GPM6A,ITPR2
3.688e-03	-5.60	solute:monoatomic cation symporter activity	molecular function	GO:0015294	117	3	18094	48	SLC1A2,SLC4A4,SLC1A3
3.697e-03	-5.60	response to auditory stimulus	biological process	GO:0010996	33	2	18204	50	SLC1A3,ATP1A2
3.741e-03	-5.59	connective tissue development	biological process	GO:0061448	232	4	18204	50	NFIA,CSGALNACT1,BMPR1B,SOX5
3.758e-03	-5.58	plasma membrane bounded cell projection organization	biological process	GO:0120036	1152	9	18204	50	CTNNA2,GPM6A,PARD3,TNIK,BMPR1B,PTPRZ1,CTNND2,RFX4,ABLIM1
3.799e-03	-5.57	DAG and IP3 signaling	REACTOME pathways	R-HSA-1489509	34	2	10285	28	ITPR2,ADCY2
3.878e-03	-5.55	organic acid:sodium symporter activity	molecular function	GO:0005343	35	2	18094	48	SLC1A3,SLC1A2
3.921e-03	-5.54	polysaccharide biosynthetic process	biological process	GO:0000271	34	2	18204	50	CSGALNACT1,FUT9
3.936e-03	-5.54	rhabdomyosarcoma	COSMIC cancer mutations	rhabdomyosarcoma	4150	21	16828	49	PPP2R2B,FMN2,PTPRZ1,RYR3,CTNND2,NHSL1,NPAS3,AQP4,ADCY2,NFIA,SLC1A3,TRPS1,RORA,PARD3,PARD3B,CDH20,GLIS3,SORBS1,MAML2,SPARCL1,MACF1
3.969e-03	-5.53	NCK2 (NCK adaptor protein 2)	protein interactions	8440	252	4	19454	50	SORBS1,NTRK2,TNIK,NHSL1
3.979e-03	-5.53	glutamatergic synapse	cellular component	GO:0098978	412	5	19108	49	SPARCL1,GPM6A,TNIK,NRG3,SLC1A2
4.052e-03	-5.51	glial cell projection	cellular component	GO:0097386	37	2	19108	49	AQP4,SLC1A2
4.071e-03	-5.50	PADI3 (peptidyl arginine deiminase 3)	protein interactions	51702	37	2	19454	50	CSGALNACT1,SPARCL1
4.209e-03	-5.47	AQUAPORIN4	prints domains	PR02016	1	1	5227	22	AQP4
4.209e-03	-5.47	NTKRECEPTOR2	prints domains	PR01941	1	1	5227	22	NTRK2
4.244e-03	-5.46	P_typ_ATPase_HD_dom	interpro domains	IPR044492	36	2	18521	50	ATP13A4,ATP1A2
4.244e-03	-5.46	ATPase_P-typ_cyto_dom_N	interpro domains	IPR023299	36	2	18521	50	ATP13A4,ATP1A2
4.244e-03	-5.46	P_typ_ATPase	interpro domains	IPR001757	36	2	18521	50	ATP1A2,ATP13A4
4.244e-03	-5.46	ATPase_P-typ_transduc_dom_A_sf	interpro domains	IPR008250	36	2	18521	50	ATP1A2,ATP13A4
4.244e-03	-5.46	ATPase_P-typ_P_site	interpro domains	IPR018303	36	2	18521	50	ATP13A4,ATP1A2
4.252e-03	-5.46	EGFR interacts with phospholipase C-gamma	REACTOME pathways	R-HSA-212718	36	2	10285	28	ITPR2,ADCY2
4.252e-03	-5.46	PLC-gamma1 signalling	REACTOME pathways	R-HSA-167021	36	2	10285	28	ITPR2,ADCY2
4.257e-03	-5.46	response to endogenous stimulus	biological process	GO:0009719	1402	10	18204	50	RYR3,NFIA,ITPR2,SLC1A3,SORBS1,SLC1A2,BMPR1B,SOX5,ATP1A2,NTRK2
4.335e-03	-5.44	kidney-other-neoplasm	COSMIC cancer mutations	kidney-other-neoplasm	10653	40	16828	49	NHSL1,NPAS3,ATP1A2,AQP4,PPP2R2B,FMN2,RFX4,ATP13A4,RYR3,GPC5,SORBS1,MAML2,MACF1,GPM6A,NTRK2,SPARCL1,SLC1A3,TRPS1,ZBTB20,PARD3,CPE,CTNND2,SOX5,ADCY2,SFXN5,NEBL,NRG3,LSAMP,CSGALNACT1,NKAIN3,PTPRZ1,FBXL7,ITPR2,MGAT4C,ABLIM1,DTNA,SLC1A2,CDH20,TNIK,RORA
4.370e-03	-5.43	striated muscle contraction	biological process	GO:0006941	120	3	18204	50	DTNA,RYR3,ATP1A2
4.373e-03	-5.43	MARK2 (microtubule affinity regulating kinase 2)	protein interactions	2011	259	4	19454	50	DTNA,PARD3,PPP2R2B,PARD3B
4.448e-03	-5.42	central_nervous_system-brainstem-glioma-oligoastrocytoma_Grade_III	COSMIC cancer mutations	central_nervous_system-brainstem-glioma-oligoastrocytoma_Grade_III	114	3	16828	49	SLC1A2,SOX5,RYR3
4.448e-03	-5.42	Lima1 (LIM domain and actin binding 1)	protein interactions	65970	129	3	19454	50	ITPR2,ZBTB20,ABLIM1
4.478e-03	-5.41	ATPase_P-typ_TM_dom_sf	interpro domains	IPR023298	37	2	18521	50	ATP1A2,ATP13A4
4.494e-03	-5.41	DIRAS3 (DIRAS family GTPase 3)	protein interactions	9077	261	4	19454	50	PARD3,MACF1,DTNA,FMN2
4.603e-03	-5.38	organic anion transport	biological process	GO:0015711	398	5	18204	50	SLC4A4,SFXN5,NTRK2,SLC1A3,SLC1A2
4.631e-03	-5.38	positive regulation of glucose import	biological process	GO:0046326	37	2	18204	50	SLC1A2,SORBS1
4.631e-03	-5.38	positive regulation of nucleotide metabolic process	biological process	GO:0045981	37	2	18204	50	SLC4A4,ZBTB20
4.631e-03	-5.38	positive regulation of purine nucleotide metabolic process	biological process	GO:1900544	37	2	18204	50	ZBTB20,SLC4A4
4.691e-03	-5.36	monoatomic cation transport	biological process	GO:0006812	766	7	18204	50	ATP1A2,GPM6A,ITPR2,ATP13A4,SLC1A3,RYR3,SLC4A4
4.744e-03	-5.35	CTNNBIP1 (catenin beta interacting protein 1)	protein interactions	56998	40	2	19454	50	CTNNA2,PPP2R2B
4.744e-03	-5.35	DZIP1 (DAZ interacting zinc finger protein 1)	protein interactions	22873	40	2	19454	50	PARD3,NTRK2
4.835e-03	-5.33	skin-head_neck-malignant_melanoma-superficial_spreading	COSMIC cancer mutations	skin-head_neck-malignant_melanoma-superficial_spreading	923	8	16828	49	CTNND2,SORBS1,MGAT4C,ADCY2,MACF1,PPP2R2B,FUT9,ATP13A4
4.868e-03	-5.33	Calcium-transporting ATPase, cytoplasmic transduction domain A	gene3d domains	2.70.150.10	36	2	14470	42	ATP13A4,ATP1A2
4.868e-03	-5.33	Calcium-transporting ATPase, cytoplasmic domain N	gene3d domains	3.40.1110.10	36	2	14470	42	ATP1A2,ATP13A4
4.868e-03	-5.33	dendrite	cellular component	GO:0030425	620	6	19108	49	CTNND2,GPM6A,BMPR1B,ATP1A2,NTRK2,ADCY2
4.880e-03	-5.32	amino acid import across plasma membrane	biological process	GO:0089718	38	2	18204	50	SLC1A3,SLC1A2
4.915e-03	-5.32	cell projection organization	biological process	GO:0030030	1200	9	18204	50	TNIK,PTPRZ1,BMPR1B,CTNNA2,PARD3,GPM6A,ABLIM1,CTNND2,RFX4
4.944e-03	-5.31	dendritic tree	cellular component	GO:0097447	622	6	19108	49	ADCY2,ATP1A2,NTRK2,BMPR1B,CTNND2,GPM6A
4.945e-03	-5.31	NUFIP1 (nuclear FMR1 interacting protein 1)	protein interactions	26747	134	3	19454	50	CPE,GPM6A,NTM
4.963e-03	-5.31	head development	biological process	GO:0060322	774	7	18204	50	RFX4,RORA,NRG3,SLC1A2,NTRK2,ATP1A2,CTNNA2
4.977e-03	-5.30	striated_muscle	COSMIC cancer mutations	striated_muscle	4228	21	16828	49	NFIA,SLC1A3,TRPS1,PARD3,RORA,PARD3B,CDH20,GLIS3,SORBS1,MAML2,SPARCL1,MACF1,PPP2R2B,PTPRZ1,FMN2,RYR3,CTNND2,NHSL1,NPAS3,AQP4,ADCY2
5.049e-03	-5.29	Myo1c (myosin IC)	protein interactions	17913	135	3	19454	50	ITPR2,TRPS1,ABLIM1
5.109e-03	-5.28	forebrain development	biological process	GO:0030900	408	5	18204	50	SLC1A2,NRG3,ATP1A2,NTRK2,RFX4
5.127e-03	-5.27	EF-hand-dom_pair	interpro domains	IPR011992	258	4	18521	50	MACF1,SPARCL1,DTNA,RYR3
5.134e-03	-5.27	Fkbp1b (FK506 binding protein 1b)	protein interactions	14226	2	1	19454	50	BMPR1B
5.134e-03	-5.27	Klhl1 (kelch-like 1)	protein interactions	93688	2	1	19454	50	BMPR1B
5.134e-03	-5.27	Ppp3cc (protein phosphatase 3, catalytic subunit, gamma isoform)	protein interactions	19057	2	1	19454	50	BMPR1B
5.134e-03	-5.27	Sh3kbp1 (SH3-domain kinase binding protein 1)	protein interactions	58194	2	1	19454	50	BMPR1B
5.134e-03	-5.27	Kdm4c (lysine (K)-specific demethylase 4C)	protein interactions	76804	2	1	19454	50	GLIS3
5.134e-03	-5.27	Zmym2 (zinc finger, MYM-type 2)	protein interactions	76007	2	1	19454	50	GLIS3
5.134e-03	-5.27	Irf7 (interferon regulatory factor 7)	protein interactions	54123	2	1	19454	50	BMPR1B
5.134e-03	-5.27	Fkbp1a (FK506 binding protein 1a)	protein interactions	14225	2	1	19454	50	BMPR1B
5.134e-03	-5.27	Fbxo34 (F-box protein 34)	protein interactions	78938	2	1	19454	50	BMPR1B
5.134e-03	-5.27	Mknk2 (MAP kinase-interacting serine/threonine kinase 2)	protein interactions	17347	2	1	19454	50	BMPR1B
5.134e-03	-5.27	Bmpr2 (bone morphogenetic protein receptor type 2)	protein interactions	12168	2	1	19454	50	BMPR1B
5.134e-03	-5.27	Bcr (BCR activator of RhoGEF and GTPase)	protein interactions	110279	2	1	19454	50	BMPR1B
5.134e-03	-5.27	sodium ion homeostasis	biological process	GO:0055078	39	2	18204	50	SLC1A3,ATP1A2
5.157e-03	-5.27	animal organ morphogenesis	biological process	GO:0009887	988	8	18204	50	CTNNA2,BMPR1B,CSGALNACT1,NRG3,SOX5,NTRK2,CPE,ABLIM1
5.366e-03	-5.23	NFIB (nuclear factor I B)	protein interactions	4781	138	3	19454	50	SOX5,TRPS1,NFIA
5.377e-03	-5.23	somatodendritic compartment	cellular component	GO:0036477	842	7	19108	49	NTRK2,ATP1A2,BMPR1B,SLC1A3,GPM6A,CTNND2,ADCY2
5.392e-03	-5.22	Formin_Cappuccino_subfam	interpro domains	IPR001265	2	1	18521	50	FMN2
5.392e-03	-5.22	Osteonectin_CS	interpro domains	IPR001999	2	1	18521	50	SPARCL1
5.392e-03	-5.22	Alpha_CARP_receptor-type	interpro domains	IPR041887	2	1	18521	50	PTPRZ1
5.392e-03	-5.22	Distrobrevin	interpro domains	IPR017432	2	1	18521	50	DTNA
5.392e-03	-5.22	MSI_RRM2	interpro domains	IPR034126	2	1	18521	50	MSI2
5.395e-03	-5.22	cyclic purine nucleotide metabolic process	biological process	GO:0052652	40	2	18204	50	RORA,ADCY2
5.409e-03	-5.22	I-set	pfam domains	PF07679	132	3	17795	48	NTM,LSAMP,NTRK2
5.432e-03	-5.22	Ig_I-set	interpro domains	IPR013098	132	3	18521	50	NTRK2,LSAMP,NTM
5.440e-03	-5.21	sarcoplasmic reticulum membrane	cellular component	GO:0033017	43	2	19108	49	ITPR2,RYR3
5.462e-03	-5.21	lung-carcinoma-adenocarcinoma	COSMIC cancer mutations	lung-carcinoma-adenocarcinoma	15133	49	16828	49	SLC1A3,MSI2,NTM,ZBTB20,MAML2,MACF1,GPM6A,SPARCL1,PPP2R2B,RFX4,GPC5,NHSL1,NPAS3,AQP4,NFIA,DTNA,SLC1A2,BMPR1B,PARD3B,GLIS3,LSAMP,CSGALNACT1,SFXN5,TRPS1,PARD3,SORBS1,NTRK2,FMN2,ATP13A4,RYR3,ATP1A2,PITPNC1,ABLIM1,TNIK,CDH20,SLC4A4,RORA,MGAT4C,NRG3,FUT9,NKAIN3,PTPRZ1,FBXL7,ITPR2,CPE,CTNND2,SOX5,NEBL,ADCY2
5.482e-03	-5.21	Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour	COSMIC cancer mutations	Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour	7434	31	16828	49	TRPS1,ZBTB20,PARD3,SLC1A3,MACF1,NTRK2,SPARCL1,MAML2,SORBS1,FMN2,RYR3,ATP13A4,PPP2R2B,NPAS3,ATP1A2,PARD3B,TNIK,SLC4A4,RORA,ABLIM1,DTNA,GLIS3,PTPRZ1,ITPR2,NRG3,CSGALNACT1,NKAIN3,ADCY2,NEBL,CTNND2,SOX5
5.486e-03	-5.21	chondroitin sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process	biological process	GO:0050653	2	1	18204	50	CSGALNACT1
5.486e-03	-5.21	neuronal stem cell division	biological process	GO:0036445	2	1	18204	50	FUT9
5.486e-03	-5.21	UDP-glucuronate metabolic process	biological process	GO:0046398	2	1	18204	50	CSGALNACT1
5.492e-03	-5.20	organic anion transmembrane transporter activity	molecular function	GO:0008514	268	4	18094	48	SLC1A3,SLC4A4,SLC1A2,SFXN5
5.541e-03	-5.20	ZDHHC17 (zinc finger DHHC-type palmitoyltransferase 17)	protein interactions	23390	277	4	19454	50	FUT9,SLC1A3,NEBL,GPM6A
5.545e-03	-5.19	neutral L-amino acid transmembrane transporter activity	molecular function	GO:0015175	42	2	18094	48	SLC1A2,SLC1A3
5.612e-03	-5.18	calcium ion transmembrane transporter activity	molecular function	GO:0015085	136	3	18094	48	ITPR2,GPM6A,RYR3
5.662e-03	-5.17	cyclic nucleotide metabolic process	biological process	GO:0009187	41	2	18204	50	ADCY2,RORA
5.755e-03	-5.16	clear_cell_renal_cell_carcinoma	COSMIC cancer mutations	clear_cell_renal_cell_carcinoma	13924	47	16828	49	SORBS1,NTRK2,TRPS1,PARD3,ATP1A2,PITPNC1,FMN2,RYR3,ATP13A4,MGAT4C,ABLIM1,CDH20,TNIK,SLC4A4,RORA,CPE,CTNND2,SOX5,NEBL,ADCY2,FUT9,NRG3,NKAIN3,PTPRZ1,FBXL7,ITPR2,MAML2,MACF1,GPM6A,SPARCL1,SLC1A3,MSI2,ZBTB20,NHSL1,NPAS3,AQP4,PPP2R2B,GPC5,GLIS3,NFIA,SLC1A2,BMPR1B,DTNA,PARD3B,SFXN5,LSAMP,CSGALNACT1
5.755e-03	-5.16	kidney-carcinoma-clear_cell_renal_cell_carcinoma	COSMIC cancer mutations	kidney-carcinoma-clear_cell_renal_cell_carcinoma	13924	47	16828	49	TRPS1,PARD3,NTRK2,SORBS1,FMN2,RYR3,ATP13A4,PITPNC1,ATP1A2,TNIK,CDH20,SLC4A4,RORA,ABLIM1,MGAT4C,PTPRZ1,FBXL7,ITPR2,FUT9,NRG3,NKAIN3,NEBL,ADCY2,CPE,CTNND2,SOX5,MSI2,ZBTB20,SLC1A3,MACF1,GPM6A,SPARCL1,MAML2,GPC5,PPP2R2B,AQP4,NHSL1,NPAS3,PARD3B,NFIA,SLC1A2,BMPR1B,DTNA,GLIS3,LSAMP,CSGALNACT1,SFXN5
5.797e-03	-5.15	-	gene3d domains	6.20.350.10	2	1	14470	42	RYR3
5.797e-03	-5.15	Vinculin, Vh2 four-helix bundle	gene3d domains	1.20.120.810	2	1	14470	42	CTNNA2
5.817e-03	-5.15	regulation of sequestering of calcium ion	biological process	GO:0051282	133	3	18204	50	ATP1A2,ITPR2,RYR3
5.885e-03	-5.14	central_nervous_system-brain-glioma-oligodendroglioma_Grade_III	COSMIC cancer mutations	central_nervous_system-brain-glioma-oligodendroglioma_Grade_III	249	4	16828	49	MACF1,PTPRZ1,GLIS3,MGAT4C
5.922e-03	-5.13	SLC6A15 (solute carrier family 6 member 15)	protein interactions	55117	143	3	19454	50	PARD3,NTRK2,SFXN5
5.935e-03	-5.13	Schwann cell development	biological process	GO:0014044	42	2	18204	50	PARD3,NTRK2
5.944e-03	-5.13	ductolobular_carcinoma	COSMIC cancer mutations	ductolobular_carcinoma	1619	11	16828	49	CPE,SORBS1,CTNND2,MACF1,ABLIM1,DTNA,FMN2,PTPRZ1,PARD3B,CDH20,RORA
5.944e-03	-5.13	breast-carcinoma-ductolobular_carcinoma	COSMIC cancer mutations	breast-carcinoma-ductolobular_carcinoma	1619	11	16828	49	SORBS1,CPE,CTNND2,MACF1,ABLIM1,DTNA,CDH20,PTPRZ1,FMN2,PARD3B,RORA
5.968e-03	-5.12	small_intestine	COSMIC cancer mutations	small_intestine	250	4	16828	49	CSGALNACT1,MGAT4C,TNIK,MACF1
6.001e-03	-5.12	YWHAH (tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein eta)	protein interactions	7533	1083	8	19454	50	NHSL1,MACF1,PARD3B,PARD3,ABLIM1,FMN2,PITPNC1,SORBS1
6.024e-03	-5.11	Vasopressin regulates renal water homeostasis via Aquaporins	REACTOME pathways	R-HSA-432040	43	2	10285	28	AQP4,ADCY2
6.037e-03	-5.11	Calml3 (calmodulin-like 3)	protein interactions	70405	144	3	19454	50	ABLIM1,ZBTB20,MACF1
6.087e-03	-5.10	phosphatidylinositol binding	molecular function	GO:0035091	276	4	18094	48	PARD3B,PARD3,ITPR2,PITPNC1
6.107e-03	-5.10	axon	cellular component	GO:0030424	650	6	19108	49	CTNNA2,GPM6A,DTNA,SLC1A2,PARD3,NTRK2
6.108e-03	-5.10	LCK (LCK proto-oncogene, Src family tyrosine kinase)	protein interactions	3932	455	5	19454	50	FMN2,CTNND2,DTNA,PARD3,MACF1
6.237e-03	-5.08	intracellular monoatomic cation homeostasis	biological process	GO:0030003	428	5	18204	50	ATP13A4,SLC1A3,ATP1A2,SLC4A4,RYR3
6.257e-03	-5.07	active transmembrane transporter activity	molecular function	GO:0022804	444	5	18094	48	SLC1A3,ATP13A4,SLC1A2,SLC4A4,ATP1A2
6.272e-03	-5.07	cell differentiation	biological process	GO:0030154	3645	18	18204	50	NTRK2,FMN2,PTPRZ1,SOX5,NEBL,CTNNA2,CTNND2,NTM,NFIA,BMPR1B,TNIK,PARD3,MSI2,GPM6A,FUT9,SLC1A3,NHSL1,RORA
6.328e-03	-5.06	cellular developmental process	biological process	GO:0048869	3648	18	18204	50	RORA,FUT9,SLC1A3,NHSL1,PARD3,GPM6A,MSI2,TNIK,BMPR1B,NFIA,CTNND2,NTM,CTNNA2,NTRK2,FMN2,PTPRZ1,NEBL,SOX5
6.372e-03	-5.06	haematopoietic_and_lymphoid_tissue-haematopoietic_neoplasm-acute_myeloid_leukaemia	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue-haematopoietic_neoplasm-acute_myeloid_leukaemia	10418	39	16828	49	ATP1A2,NPAS3,NHSL1,PPP2R2B,GPC5,FMN2,RFX4,RYR3,ATP13A4,MAML2,SPARCL1,MACF1,NTRK2,SLC1A3,PARD3,MSI2,NTM,CTNND2,SOX5,CPE,SFXN5,NEBL,ADCY2,NKAIN3,CSGALNACT1,LSAMP,NRG3,ITPR2,PTPRZ1,FBXL7,GLIS3,NFIA,SLC1A2,ABLIM1,SLC4A4,RORA,PARD3B,TNIK,CDH20
6.372e-03	-5.06	acute_myeloid_leukaemia	COSMIC cancer mutations	acute_myeloid_leukaemia	10418	39	16828	49	ATP1A2,NHSL1,NPAS3,PPP2R2B,GPC5,ATP13A4,RYR3,RFX4,FMN2,MAML2,SPARCL1,NTRK2,MACF1,SLC1A3,PARD3,MSI2,NTM,SOX5,CTNND2,CPE,ADCY2,SFXN5,NEBL,NKAIN3,CSGALNACT1,LSAMP,NRG3,ITPR2,FBXL7,PTPRZ1,GLIS3,SLC1A2,NFIA,ABLIM1,RORA,SLC4A4,CDH20,TNIK,PARD3B
6.402e-03	-5.05	skin-extremity-malignant_melanoma	COSMIC cancer mutations	skin-extremity-malignant_melanoma	1875	12	16828	49	ADCY2,NEBL,PITPNC1,RYR3,FBXL7,ATP13A4,PTPRZ1,FMN2,FUT9,NTRK2,PARD3,CDH20
6.429e-03	-5.05	extremity	COSMIC cancer mutations	extremity	1876	12	16828	49	NTRK2,PARD3,CDH20,NEBL,ADCY2,PITPNC1,RYR3,FBXL7,ATP13A4,PTPRZ1,FMN2,FUT9
6.435e-03	-5.05	cytoskeleton organization	biological process	GO:0007010	1251	9	18204	50	ABLIM1,NEBL,PARD3B,TNIK,FMN2,SORBS1,CTNNA2,MACF1,PARD3
6.441e-03	-5.05	membrane raft	cellular component	GO:0045121	290	4	19108	49	ATP1A2,ADCY2,SLC1A2,SORBS1
6.441e-03	-5.04	regulation of generation of precursor metabolites and energy	biological process	GO:0043467	138	3	18204	50	SORBS1,SLC4A4,ZBTB20
6.454e-03	-5.04	leg	COSMIC cancer mutations	leg	969	8	16828	49	NEBL,PTPRZ1,NTM,FMN2,ATP13A4,SLC4A4,ZBTB20,NRG3
6.472e-03	-5.04	ATPASE_E1_E2	prosite domains	PS00154	36	2	12186	41	ATP1A2,ATP13A4
6.498e-03	-5.04	positive regulation of glucose transmembrane transport	biological process	GO:0010828	44	2	18204	50	SLC1A2,SORBS1
6.500e-03	-5.04	BDNF (brain derived neurotrophic factor)	protein interactions	627	47	2	19454	50	NTRK2,CPE
6.500e-03	-5.04	CNTN1 (contactin 1)	protein interactions	1272	47	2	19454	50	PTPRZ1,GPM6A
6.557e-03	-5.03	Cardiac conduction	REACTOME pathways	R-HSA-5576891	142	3	10285	28	ITPR2,ATP1A2,RYR3
6.597e-03	-5.02	membrane microdomain	cellular component	GO:0098857	292	4	19108	49	ATP1A2,SLC1A2,ADCY2,SORBS1
6.634e-03	-5.02	GSE1 (Gse1 coiled-coil protein)	protein interactions	23199	149	3	19454	50	TNIK,SOX5,NFIA
6.634e-03	-5.02	vascular process in circulatory system	biological process	GO:0003018	273	4	18204	50	SLC4A4,ATP1A2,SLC1A3,SLC1A2
6.645e-03	-5.01	chondroitin biosynthesis	BIOCYC pathways	HUMAN_PWY-6566	2	1	902	3	CSGALNACT1
6.660e-03	-5.01	skin-leg-malignant_melanoma-nodular	COSMIC cancer mutations	skin-leg-malignant_melanoma-nodular	258	4	16828	49	SLC4A4,ATP13A4,PTPRZ1,FMN2
6.676e-03	-5.01	inorganic cation transmembrane transport	biological process	GO:0098662	618	6	18204	50	ITPR2,ATP1A2,SLC1A3,RYR3,GPM6A,SLC4A4
6.702e-03	-5.01	neurotransmitter transport	biological process	GO:0006836	140	3	18204	50	SLC1A2,SLC1A3,ATP1A2
6.709e-03	-5.00	apical junction complex	cellular component	GO:0043296	150	3	19108	49	SORBS1,PARD3,PARD3B
6.718e-03	-5.00	OSTEONECTIN_1	prosite domains	PS00612	2	1	12186	41	SPARCL1
6.718e-03	-5.00	OSTEONECTIN_2	prosite domains	PS00613	2	1	12186	41	SPARCL1
6.798e-03	-4.99	intracellular monoatomic ion homeostasis	biological process	GO:0006873	437	5	18204	50	ATP1A2,SLC1A3,ATP13A4,RYR3,SLC4A4
6.804e-03	-4.99	gliogenesis	biological process	GO:0042063	275	4	18204	50	NTRK2,PTPRZ1,NFIA,PARD3
6.932e-03	-4.97	soft_tissue-striated_muscle-rhabdomyosarcoma-embryonal	COSMIC cancer mutations	soft_tissue-striated_muscle-rhabdomyosarcoma-embryonal	2659	15	16828	49	PTPRZ1,FMN2,RYR3,AQP4,ADCY2,CTNND2,NPAS3,RORA,PARD3B,NFIA,SPARCL1,MACF1,GLIS3,SORBS1,MAML2
6.932e-03	-4.97	embryonal	COSMIC cancer mutations	embryonal	2659	15	16828	49	RYR3,PTPRZ1,FMN2,ADCY2,AQP4,NPAS3,CTNND2,PARD3B,RORA,NFIA,MACF1,SPARCL1,SORBS1,MAML2,GLIS3
6.969e-03	-4.97	monoatomic anion transmembrane transport	biological process	GO:0098656	142	3	18204	50	SLC1A3,SLC1A2,SLC4A4
6.969e-03	-4.97	positive regulation of small molecule metabolic process	biological process	GO:0062013	142	3	18204	50	ZBTB20,SLC4A4,SORBS1
7.084e-03	-4.95	regulation of myelination	biological process	GO:0031641	46	2	18204	50	PTPRZ1,PARD3
7.087e-03	-4.95	symporter activity	molecular function	GO:0015293	148	3	18094	48	SLC1A3,SLC1A2,SLC4A4
7.135e-03	-4.94	SOX6 (SRY-box transcription factor 6)	protein interactions	55553	153	3	19454	50	SOX5,TRPS1,NFIA
7.163e-03	-4.94	PLC beta mediated events	REACTOME pathways	R-HSA-112043	47	2	10285	28	ITPR2,ADCY2
7.191e-03	-4.93	regulation of neuron projection development	biological process	GO:0010975	443	5	18204	50	FUT9,NTRK2,TNIK,MACF1,CTNNA2
7.243e-03	-4.93	glycoprotein biosynthetic process	biological process	GO:0009101	280	4	18204	50	CSGALNACT1,BMPR1B,MGAT4C,FUT9
7.263e-03	-4.93	cellular response to oxygen-containing compound	biological process	GO:1901701	1047	8	18204	50	RYR3,RORA,ZBTB20,SLC1A3,ADCY2,ITPR2,SORBS1,SLC1A2
7.312e-03	-4.92	metal ion transport	biological process	GO:0030001	630	6	18204	50	ITPR2,ATP1A2,SLC1A3,RYR3,GPM6A,SLC4A4
7.364e-03	-4.91	soft_tissue-striated_muscle-rhabdomyosarcoma-alveolar	COSMIC cancer mutations	soft_tissue-striated_muscle-rhabdomyosarcoma-alveolar	2414	14	16828	49	SORBS1,SPARCL1,MACF1,NFIA,SLC1A3,TRPS1,PARD3,PARD3B,CDH20,NHSL1,NPAS3,PPP2R2B,FMN2,RYR3
7.364e-03	-4.91	alveolar	COSMIC cancer mutations	alveolar	2414	14	16828	49	NFIA,SLC1A3,PARD3B,CDH20,TRPS1,PARD3,SORBS1,MACF1,SPARCL1,PPP2R2B,FMN2,RYR3,NHSL1,NPAS3
7.386e-03	-4.91	regulation of neuron migration	biological process	GO:2001222	47	2	18204	50	CTNNA2,NRG3
7.386e-03	-4.91	Schwann cell differentiation	biological process	GO:0014037	47	2	18204	50	NTRK2,PARD3
7.394e-03	-4.91	PPP2R2D (protein phosphatase 2 regulatory subunit Bdelta)	protein interactions	55844	155	3	19454	50	PPP2R2B,GPC5,CSGALNACT1
7.462e-03	-4.90	G-protein mediated events	REACTOME pathways	R-HSA-112040	48	2	10285	28	ITPR2,ADCY2
7.515e-03	-4.89	Wnt signaling pathway	biological process	GO:0016055	283	4	18204	50	CPE,MACF1,TNIK,CTNND2
7.525e-03	-4.89	CEP19 (centrosomal protein 19)	protein interactions	84984	156	3	19454	50	FMN2,ABLIM1,PARD3
7.592e-03	-4.88	enteropathy_type_T_cell_lymphoma	COSMIC cancer mutations	enteropathy_type_T_cell_lymphoma	45	2	16828	49	MACF1,MGAT4C
7.592e-03	-4.88	haematopoietic_and_lymphoid_tissue-small_intestine-lymphoid_neoplasm-enteropathy_type_T_cell_lymphoma	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue-small_intestine-lymphoid_neoplasm-enteropathy_type_T_cell_lymphoma	45	2	16828	49	MACF1,MGAT4C
7.617e-03	-4.88	FAM171B (family with sequence similarity 171 member B)	protein interactions	165215	51	2	19454	50	NTRK2,PARD3
7.617e-03	-4.88	Ndc80 (NDC80 kinetochore complex component)	protein interactions	67052	51	2	19454	50	MACF1,NHSL1
7.631e-03	-4.88	human chr8q23.3	chromosome location	human chr8q23.3	4	1	26134	50	TRPS1
7.691e-03	-4.87	Smad6 (SMAD family member 6)	protein interactions	17130	3	1	19454	50	BMPR1B
7.691e-03	-4.87	IL34 (interleukin 34)	protein interactions	146433	3	1	19454	50	PTPRZ1
7.691e-03	-4.87	Plekhb1 (pleckstrin homology domain containing, family B (evectins) member 1)	protein interactions	27276	3	1	19454	50	BMPR1B
7.691e-03	-4.87	Spop (speckle-type BTB/POZ protein)	protein interactions	20747	3	1	19454	50	GLIS3
7.691e-03	-4.87	Rap2a (RAS related protein 2a)	protein interactions	76108	3	1	19454	50	BMPR1B
7.691e-03	-4.87	Chn1 (chimerin 1)	protein interactions	108699	3	1	19454	50	BMPR1B
7.691e-03	-4.87	Fbxw5 (F-box and WD-40 domain protein 5)	protein interactions	30839	3	1	19454	50	BMPR1B
7.691e-03	-4.87	Stk35 (serine/threonine kinase 35)	protein interactions	67333	3	1	19454	50	BMPR1B
7.691e-03	-4.87	BCO1 (beta-carotene oxygenase 1)	protein interactions	53630	3	1	19454	50	ABLIM1
7.691e-03	-4.87	Atg16l1 (autophagy related 16 like 1)	protein interactions	77040	3	1	19454	50	BMPR1B
7.691e-03	-4.87	QRFPR (pyroglutamylated RFamide peptide receptor)	protein interactions	84109	3	1	19454	50	NTM
7.691e-03	-4.87	Usp45 (ubiquitin specific petidase 45)	protein interactions	77593	3	1	19454	50	BMPR1B
7.700e-03	-4.87	astrocytoma_Grade_I	COSMIC cancer mutations	astrocytoma_Grade_I	139	3	16828	49	NRG3,PARD3,GPC5
7.702e-03	-4.87	animal organ development	biological process	GO:0048513	2846	15	18204	50	SOX5,NEBL,NRG3,ATP1A2,NTRK2,CTNNA2,ABLIM1,RFX4,CPE,NFIA,SLC1A2,CSGALNACT1,BMPR1B,GPM6A,RORA
7.720e-03	-4.86	endometrium-carcinoma-serous_carcinoma	COSMIC cancer mutations	endometrium-carcinoma-serous_carcinoma	1442	10	16828	49	SORBS1,CTNND2,LSAMP,FMN2,RYR3,TNIK,SLC4A4,TRPS1,GPC5,PARD3
7.762e-03	-4.86	anchoring junction	cellular component	GO:0070161	902	7	19108	49	SORBS1,ATP1A2,PARD3B,PARD3,CDH20,CTNNA2,CTNND2
7.802e-03	-4.85	EF-hand	gene3d domains	1.10.238.10	272	4	14470	42	SPARCL1,DTNA,MACF1,RYR3
7.832e-03	-4.85	response to organic cyclic compound	biological process	GO:0014070	843	7	18204	50	RORA,RYR3,ITPR2,ADCY2,SLC1A3,SLC1A2,ATP1A2
7.909e-03	-4.84	SH2B2 (SH2B adaptor protein 2)	protein interactions	10603	52	2	19454	50	SORBS1,NTRK2
7.938e-03	-4.84	inositol 1,4,5-trisphosphate-gated calcium channel activity	molecular function	GO:0005220	3	1	18094	48	ITPR2
7.938e-03	-4.84	glucuronylgalactosylproteoglycan 4-beta-N-acetylgalactosaminyltransferase activity	molecular function	GO:0047237	3	1	18094	48	CSGALNACT1
7.938e-03	-4.84	alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity	molecular function	GO:0008454	3	1	18094	48	MGAT4C
7.938e-03	-4.84	cysteine transmembrane transporter activity	molecular function	GO:0033229	3	1	18094	48	SLC1A2
8.065e-03	-4.82	SOX5 (SRY-box transcription factor 5)	protein interactions	6660	160	3	19454	50	NFIA,TRPS1,SOX5
8.071e-03	-4.82	RYDR_Jsol	pfam domains	PF21119	3	1	17795	48	RYR3
8.071e-03	-4.82	LRRCT_2	pfam domains	PF16920	3	1	17795	48	NTRK2
8.071e-03	-4.82	MamL-1	pfam domains	PF09596	3	1	17795	48	MAML2
8.071e-03	-4.82	Myelin_PLP	pfam domains	PF01275	3	1	17795	48	GPM6A
8.071e-03	-4.82	Sorb	pfam domains	PF02208	3	1	17795	48	SORBS1
8.071e-03	-4.82	RyR	pfam domains	PF02026	3	1	17795	48	RYR3
8.071e-03	-4.82	SR_plectin_7	pfam domains	PF21097	3	1	17795	48	MACF1
8.071e-03	-4.82	RR_TM4-6	pfam domains	PF06459	3	1	17795	48	RYR3
8.078e-03	-4.82	MAML_N_sf	interpro domains	IPR046370	3	1	18521	50	MAML2
8.078e-03	-4.82	MAML1-3	interpro domains	IPR046369	3	1	18521	50	MAML2
8.078e-03	-4.82	Mastermind-like_N	interpro domains	IPR019082	3	1	18521	50	MAML2
8.078e-03	-4.82	InsP3_rcpt	interpro domains	IPR000493	3	1	18521	50	ITPR2
8.078e-03	-4.82	Neuregulin	interpro domains	IPR040180	3	1	18521	50	NRG3
8.078e-03	-4.82	SoHo_dom	interpro domains	IPR003127	3	1	18521	50	SORBS1
8.078e-03	-4.82	Vinculin_CS	interpro domains	IPR000633	3	1	18521	50	CTNNA2
8.078e-03	-4.82	ROR_rcpt	interpro domains	IPR003079	3	1	18521	50	RORA
8.078e-03	-4.82	NR_DBD_ROR	interpro domains	IPR044101	3	1	18521	50	RORA
8.078e-03	-4.82	RYDR_Jsol	interpro domains	IPR048581	3	1	18521	50	RYR3
8.078e-03	-4.82	SPRY1_RyR	interpro domains	IPR035761	3	1	18521	50	RYR3
8.078e-03	-4.82	Ryanrecept_TM4-6	interpro domains	IPR009460	3	1	18521	50	RYR3
8.078e-03	-4.82	SPRY3_RyR	interpro domains	IPR035762	3	1	18521	50	RYR3
8.078e-03	-4.82	Ryan_recept	interpro domains	IPR013333	3	1	18521	50	RYR3
8.078e-03	-4.82	Myelin_PLP	interpro domains	IPR001614	3	1	18521	50	GPM6A
8.078e-03	-4.82	NTRK_LRRCT	interpro domains	IPR031635	3	1	18521	50	NTRK2
8.078e-03	-4.82	Ryanodine_rcpt	interpro domains	IPR003032	3	1	18521	50	RYR3
8.078e-03	-4.82	SPRY2_RyR	interpro domains	IPR035764	3	1	18521	50	RYR3
8.078e-03	-4.82	NTRK	interpro domains	IPR020777	3	1	18521	50	NTRK2
8.078e-03	-4.82	Myelin_PLP_CS	interpro domains	IPR018237	3	1	18521	50	GPM6A
8.085e-03	-4.82	signaling	biological process	GO:0023052	4968	22	18204	50	RYR3,DTNA,RORA,ITPR2,SLC1A3,SORBS1,PARD3,TNIK,BMPR1B,SLC1A2,PITPNC1,CPE,NFIA,CTNND2,ADCY2,MAML2,MACF1,SPARCL1,NRG3,NTRK2,ATP1A2,FMN2
8.100e-03	-4.82	AFDN (afadin, adherens junction formation factor)	protein interactions	4301	309	4	19454	50	SORBS1,DTNA,MACF1,PARD3
8.124e-03	-4.81	neuronal cell body	cellular component	GO:0043025	489	5	19108	49	SLC1A3,GPM6A,CTNND2,BMPR1B,ATP1A2
8.218e-03	-4.80	cysteine transport	biological process	GO:0042883	3	1	18204	50	SLC1A2
8.218e-03	-4.80	cysteine transmembrane transport	biological process	GO:1903712	3	1	18204	50	SLC1A2
8.218e-03	-4.80	cardiac muscle thin filament assembly	biological process	GO:0071691	3	1	18204	50	NEBL
8.218e-03	-4.80	mammary placode formation	biological process	GO:0060596	3	1	18204	50	NRG3
8.218e-03	-4.80	radial glia guided migration of Purkinje cell	biological process	GO:0021942	3	1	18204	50	CTNNA2
8.218e-03	-4.80	regulation of calcium:sodium antiporter activity	biological process	GO:1903279	3	1	18204	50	ATP1A2
8.218e-03	-4.80	meiotic chromosome movement towards spindle pole	biological process	GO:0016344	3	1	18204	50	FMN2
8.218e-03	-4.80	trans-synaptic signaling by BDNF, modulating synaptic transmission	biological process	GO:0099183	3	1	18204	50	NTRK2
8.218e-03	-4.80	UDP-N-acetylgalactosamine metabolic process	biological process	GO:0019276	3	1	18204	50	CSGALNACT1
8.218e-03	-4.80	formin-nucleated actin cable organization	biological process	GO:0110009	3	1	18204	50	FMN2
8.218e-03	-4.80	formin-nucleated actin cable assembly	biological process	GO:0070649	3	1	18204	50	FMN2
8.301e-03	-4.79	breast-carcinoma-basal_(triple-negative)_carcinoma	COSMIC cancer mutations	breast-carcinoma-basal_(triple-negative)_carcinoma	2981	16	16828	49	NPAS3,ATP1A2,NEBL,ADCY2,NRG3,PPP2R2B,FMN2,MAML2,NTRK2,MACF1,SPARCL1,BMPR1B,NTM,MSI2,PARD3,SLC4A4
8.301e-03	-4.79	basal_(triple-negative)_carcinoma	COSMIC cancer mutations	basal_(triple-negative)_carcinoma	2981	16	16828	49	MAML2,MACF1,NTRK2,SPARCL1,BMPR1B,NTM,MSI2,SLC4A4,PARD3,NPAS3,ATP1A2,ADCY2,NEBL,NRG3,PPP2R2B,FMN2
8.387e-03	-4.78	cell cortex	cellular component	GO:0005938	313	4	19108	49	FMN2,PARD3,ITPR2,PARD3B
8.392e-03	-4.78	Chondroitin sulfate/dermatan sulfate metabolism	REACTOME pathways	R-HSA-1793185	51	2	10285	28	GPC5,CSGALNACT1
8.392e-03	-4.78	Neurotransmitter Release Cycle	REACTOME pathways	R-HSA-112310	51	2	10285	28	SLC1A3,SLC1A2
8.401e-03	-4.78	FORMIN	prints domains	PR00828	2	1	5227	22	FMN2
8.436e-03	-4.78	protein binding	molecular function	GO:0005515	13983	44	18094	48	TRPS1,PARD3,SLC1A2,NPAS3,ADCY2,ITPR2,CDH20,PTPRZ1,GPC5,NTM,SPARCL1,GPM6A,FBXL7,SFXN5,CTNNA2,CTNND2,RFX4,PPP2R2B,NEBL,BMPR1B,FUT9,MAML2,AQP4,ABLIM1,MACF1,MSI2,NFIA,RYR3,PITPNC1,GLIS3,PARD3B,FMN2,TNIK,NTRK2,NRG3,RORA,SLC1A3,ATP1A2,SOX5,SLC4A4,CPE,LSAMP,SORBS1,DTNA
8.507e-03	-4.77	SYNM (synemin)	protein interactions	23336	54	2	19454	50	PPP2R2B,DTNA
8.603e-03	-4.76	central_nervous_system-temporoparietal-glioma-astrocytoma_Grade_IV	COSMIC cancer mutations	central_nervous_system-temporoparietal-glioma-astrocytoma_Grade_IV	48	2	16828	49	RYR3,PARD3
8.683e-03	-4.75	-	gene3d domains	1.10.490.160	3	1	14470	42	RYR3
8.683e-03	-4.75	-	gene3d domains	6.10.250.2510	3	1	14470	42	CTNNA2
8.683e-03	-4.75	-	gene3d domains	6.10.250.970	3	1	14470	42	MAML2
8.702e-03	-4.74	calcium-mediated signaling	biological process	GO:0019722	154	3	18204	50	RYR3,ATP1A2,ITPR2
8.712e-03	-4.74	ATPase-coupled monoatomic cation transmembrane transporter activity	molecular function	GO:0019829	53	2	18094	48	ATP13A4,ATP1A2
8.713e-03	-4.74	Aquaporin-mediated transport	REACTOME pathways	R-HSA-445717	52	2	10285	28	AQP4,ADCY2
8.748e-03	-4.74	ZYX (zyxin)	protein interactions	7791	316	4	19454	50	SORBS1,ABLIM1,MACF1,NEBL
8.771e-03	-4.74	EGR2 (early growth response 2)	protein interactions	1959	165	3	19454	50	TRPS1,SOX5,NFIA
8.873e-03	-4.72	carboxylic acid transport	biological process	GO:0046942	297	4	18204	50	SFXN5,SLC1A2,SLC1A3,NTRK2
8.917e-03	-4.72	SCLT1 (sodium channel and clathrin linker 1)	protein interactions	132320	166	3	19454	50	NEBL,ABLIM1,ATP1A2
8.976e-03	-4.71	organic acid transport	biological process	GO:0015849	298	4	18204	50	SLC1A2,SLC1A3,NTRK2,SFXN5
8.978e-03	-4.71	cell communication	biological process	GO:0007154	5010	22	18204	50	SPARCL1,NRG3,FMN2,NTRK2,NFIA,SLC1A2,BMPR1B,PITPNC1,DTNA,SLC1A3,MAML2,MACF1,ATP1A2,CPE,ADCY2,CTNND2,SORBS1,PARD3,TNIK,RORA,RYR3,ITPR2
8.982e-03	-4.71	regulation of nucleotide catabolic process	biological process	GO:0030811	52	2	18204	50	ZBTB20,SLC4A4
8.982e-03	-4.71	regulation of glycolytic process	biological process	GO:0006110	52	2	18204	50	SLC4A4,ZBTB20
8.982e-03	-4.71	regulation of purine nucleotide catabolic process	biological process	GO:0033121	52	2	18204	50	ZBTB20,SLC4A4
9.087e-03	-4.70	metal ion binding	molecular function	GO:0046872	4239	19	18094	48	SLC1A2,ATP1A2,RYR3,SLC1A3,SPARCL1,RORA,MACF1,ABLIM1,TRPS1,BMPR1B,DTNA,ZBTB20,ITPR2,CPE,GLIS3,ADCY2,MGAT4C,CSGALNACT1,ATP13A4
9.212e-03	-4.69	PPL (periplakin)	protein interactions	5493	168	3	19454	50	PPP2R2B,NKAIN3,ITPR2
9.252e-03	-4.68	CATATPASE	prints domains	PR00119	35	2	5227	22	ATP13A4,ATP1A2
9.318e-03	-4.68	neutral amino acid transport	biological process	GO:0015804	53	2	18204	50	SLC1A2,SLC1A3
9.442e-03	-4.66	TREX2 (three prime repair exonuclease 2)	protein interactions	11219	57	2	19454	50	PARD3B,PPP2R2B
9.463e-03	-4.66	binding	molecular function	GO:0005488	16422	48	18094	48	FBXL7,SFXN5,CTNNA2,SPARCL1,GPM6A,NTM,GPC5,FUT9,BMPR1B,NEBL,RFX4,PPP2R2B,CTNND2,SLC1A2,TRPS1,PARD3,CDH20,PTPRZ1,ITPR2,ZBTB20,NPAS3,ADCY2,ATP1A2,SLC1A3,RORA,SORBS1,DTNA,LSAMP,SLC4A4,CPE,MGAT4C,SOX5,RYR3,NFIA,MACF1,MSI2,MAML2,AQP4,ABLIM1,NTRK2,TNIK,NRG3,FMN2,GLIS3,PARD3B,CSGALNACT1,PITPNC1,ATP13A4
9.485e-03	-4.66	regulation of plasma membrane bounded cell projection organization	biological process	GO:0120035	666	6	18204	50	FUT9,NTRK2,TNIK,GPM6A,MACF1,CTNNA2
9.492e-03	-4.66	monoatomic anion transport	biological process	GO:0006820	159	3	18204	50	SLC1A2,SLC1A3,SLC4A4
9.634e-03	-4.64	biliary_tract	COSMIC cancer mutations	biliary_tract	15309	49	16828	49	GLIS3,NFIA,SLC1A2,DTNA,BMPR1B,PARD3B,SFXN5,CSGALNACT1,LSAMP,MAML2,SPARCL1,MACF1,GPM6A,SLC1A3,ZBTB20,NTM,MSI2,NPAS3,NHSL1,AQP4,PPP2R2B,GPC5,RFX4,MGAT4C,ABLIM1,SLC4A4,RORA,CDH20,TNIK,CTNND2,SOX5,CPE,NEBL,ADCY2,NKAIN3,FUT9,NRG3,ITPR2,PTPRZ1,FBXL7,SORBS1,NTRK2,TRPS1,PARD3,ATP1A2,PITPNC1,FMN2,ATP13A4,RYR3
9.709e-03	-4.63	HNRNPL (heterogeneous nuclear ribonucleoprotein L)	protein interactions	3191	1958	11	19454	50	NFIA,ABLIM1,ZBTB20,MSI2,TRPS1,DTNA,PARD3,MACF1,PARD3B,NRG3,BMPR1B
9.751e-03	-4.63	dendritic spine	cellular component	GO:0043197	172	3	19108	49	GPM6A,NTRK2,ATP1A2
9.833e-03	-4.62	ROR2 (receptor tyrosine kinase like orphan receptor 2)	protein interactions	4920	327	4	19454	50	SORBS1,DTNA,TNIK,PARD3
9.950e-03	-4.61	CAV1 (caveolin 1)	protein interactions	857	719	6	19454	50	TNIK,DTNA,PARD3,MACF1,SLC1A3,FMN2
1.001e-02	-4.60	establishment or maintenance of epithelial cell apical/basal polarity	biological process	GO:0045197	55	2	18204	50	PARD3B,PARD3
1.001e-02	-4.60	response to cocaine	biological process	GO:0042220	55	2	18204	50	SLC1A2,SLC1A3
1.002e-02	-4.60	Znf_NHR/GATA	interpro domains	IPR013088	56	2	18521	50	TRPS1,RORA
1.006e-02	-4.60	VINCULIN_1	prosite domains	PS00663	3	1	12186	41	CTNNA2
1.006e-02	-4.60	MYELIN_PLP_1	prosite domains	PS00575	3	1	12186	41	GPM6A
1.006e-02	-4.60	SOHO	prosite domains	PS50831	3	1	12186	41	SORBS1
1.006e-02	-4.60	MYELIN_PLP_2	prosite domains	PS01004	3	1	12186	41	GPM6A
1.006e-02	-4.60	neuron spine	cellular component	GO:0044309	174	3	19108	49	GPM6A,NTRK2,ATP1A2
1.022e-02	-4.58	extrinsic component of membrane	cellular component	GO:0019898	175	3	19108	49	CTNNA2,CDH20,DTNA
1.022e-02	-4.58	internode region of axon	cellular component	GO:0033269	4	1	19108	49	PARD3
1.024e-02	-4.58	Naa20 (N(alpha)-acetyltransferase 20, NatB catalytic subunit)	protein interactions	67877	4	1	19454	50	BMPR1B
1.024e-02	-4.58	Ctbp2 (C-terminal binding protein 2)	protein interactions	13017	4	1	19454	50	TRPS1
1.024e-02	-4.58	Nme2 (NME/NM23 nucleoside diphosphate kinase 2)	protein interactions	18103	4	1	19454	50	RORA
1.024e-02	-4.58	Nkiras1 (NFKB inhibitor interacting Ras-like protein 1)	protein interactions	69721	4	1	19454	50	BMPR1B
1.024e-02	-4.58	Arhgef6 (Rac/Cdc42 guanine nucleotide exchange factor 6)	protein interactions	73341	4	1	19454	50	BMPR1B
1.024e-02	-4.58	IER5L (immediate early response 5 like)	protein interactions	389792	4	1	19454	50	PPP2R2B
1.024e-02	-4.58	Ilkap (integrin-linked kinase-associated serine/threonine phosphatase 2C)	protein interactions	67444	4	1	19454	50	BMPR1B
1.024e-02	-4.58	Srgap1 (SLIT-ROBO Rho GTPase activating protein 1)	protein interactions	117600	4	1	19454	50	BMPR1B
1.024e-02	-4.58	Cdk14 (cyclin dependent kinase 14)	protein interactions	18647	4	1	19454	50	BMPR1B
1.024e-02	-4.58	CCDC126 (coiled-coil domain containing 126)	protein interactions	90693	4	1	19454	50	GPM6A
1.024e-02	-4.58	Dnaja1 (DnaJ heat shock protein family (Hsp40) member A1)	protein interactions	15502	4	1	19454	50	GLIS3
1.024e-02	-4.58	Rhebl1 (Ras homolog enriched in brain like 1)	protein interactions	69159	4	1	19454	50	BMPR1B
1.029e-02	-4.58	LHX3 (LIM homeobox 3)	protein interactions	8022	175	3	19454	50	SOX5,TRPS1,NFIA
1.036e-02	-4.57	release of sequestered calcium ion into cytosol	biological process	GO:0051209	56	2	18204	50	RYR3,ITPR2
1.049e-02	-4.56	import across plasma membrane	biological process	GO:0098739	165	3	18204	50	SLC1A2,SLC1A3,ATP1A2
1.057e-02	-4.55	tricarboxylic acid transmembrane transporter activity	molecular function	GO:0015142	4	1	18094	48	SFXN5
1.057e-02	-4.55	ryanodine-sensitive calcium-release channel activity	molecular function	GO:0005219	4	1	18094	48	RYR3
1.057e-02	-4.55	citrate transmembrane transporter activity	molecular function	GO:0015137	4	1	18094	48	SFXN5
1.057e-02	-4.55	brain-derived neurotrophic factor binding	molecular function	GO:0048403	4	1	18094	48	NTRK2
1.065e-02	-4.54	ovary-other-neoplasm	COSMIC cancer mutations	ovary-other-neoplasm	12717	44	16828	49	SPARCL1,GPM6A,MACF1,MAML2,ZBTB20,MSI2,NTM,SLC1A3,AQP4,NHSL1,GPC5,RFX4,PPP2R2B,GLIS3,PARD3B,SLC1A2,BMPR1B,SFXN5,CSGALNACT1,LSAMP,NTRK2,SORBS1,PARD3,TRPS1,ATP1A2,RYR3,ATP13A4,FMN2,MGAT4C,RORA,SLC4A4,TNIK,CDH20,ABLIM1,NEBL,ADCY2,SOX5,CTNND2,CPE,ITPR2,FBXL7,NKAIN3,FUT9,NRG3
1.066e-02	-4.54	regulation of cell projection organization	biological process	GO:0031344	683	6	18204	50	MACF1,CTNNA2,GPM6A,TNIK,NTRK2,FUT9
1.072e-02	-4.54	negative regulation of sequestering of calcium ion	biological process	GO:0051283	57	2	18204	50	ITPR2,RYR3
1.072e-02	-4.54	visual behavior	biological process	GO:0007632	57	2	18204	50	ATP1A2,SLC1A2
1.075e-02	-4.53	Nebulin	pfam domains	PF00880	4	1	17795	48	NEBL
1.075e-02	-4.53	NKAIN	pfam domains	PF05640	4	1	17795	48	NKAIN3
1.075e-02	-4.53	AbLIM_anchor	pfam domains	PF16182	4	1	17795	48	ABLIM1
1.075e-02	-4.53	P5-ATPase	pfam domains	PF12409	4	1	17795	48	ATP13A4
1.075e-02	-4.53	Spectrin_3	pfam domains	PF21019	4	1	17795	48	MACF1
1.075e-02	-4.53	NfI_DNAbd_pre-N	pfam domains	PF10524	4	1	17795	48	NFIA
1.075e-02	-4.53	CTF_NFI	pfam domains	PF00859	4	1	17795	48	NFIA
1.075e-02	-4.53	Spectrin_4	pfam domains	PF21020	4	1	17795	48	MACF1
1.075e-02	-4.53	Spectrin_2	pfam domains	PF18373	4	1	17795	48	MACF1
1.075e-02	-4.53	NHS	pfam domains	PF15273	4	1	17795	48	NHSL1
1.075e-02	-4.53	Glyco_transf_54	pfam domains	PF04666	4	1	17795	48	MGAT4C
1.075e-02	-4.53	Ion transport by P-type ATPases	REACTOME pathways	R-HSA-936837	58	2	10285	28	ATP1A2,ATP13A4
1.076e-02	-4.53	PP2A_PR55_CS	interpro domains	IPR018067	4	1	18521	50	PPP2R2B
1.076e-02	-4.53	CTF/NFI	interpro domains	IPR000647	4	1	18521	50	NFIA
1.076e-02	-4.53	P5B-type_ATPase	interpro domains	IPR047821	4	1	18521	50	ATP13A4
1.076e-02	-4.53	CTF/NFI_DNA-bd_CS	interpro domains	IPR019739	4	1	18521	50	NFIA
1.076e-02	-4.53	Glyco_transf_54	interpro domains	IPR006759	4	1	18521	50	MGAT4C
1.076e-02	-4.53	CTF/NFI_DNA-bd-dom	interpro domains	IPR020604	4	1	18521	50	NFIA
1.076e-02	-4.53	NHS-like	interpro domains	IPR024845	4	1	18521	50	NHSL1
1.076e-02	-4.53	P5A-ATPase_N	interpro domains	IPR047819	4	1	18521	50	ATP13A4
1.076e-02	-4.53	CTF/NFI_DNA-bd_N	interpro domains	IPR019548	4	1	18521	50	NFIA
1.076e-02	-4.53	PCN-like_spectrin-like_rpt	interpro domains	IPR049538	4	1	18521	50	MACF1
1.076e-02	-4.53	Desmoplakin_Spectrin-like	interpro domains	IPR041573	4	1	18521	50	MACF1
1.076e-02	-4.53	Na/K-Atpase_Interacting	interpro domains	IPR008516	4	1	18521	50	NKAIN3
1.076e-02	-4.53	PP2A_PR55	interpro domains	IPR000009	4	1	18521	50	PPP2R2B
1.076e-02	-4.53	AbLIM_anchor	interpro domains	IPR032402	4	1	18521	50	ABLIM1
1.076e-02	-4.53	Nebulin_repeat	interpro domains	IPR000900	4	1	18521	50	NEBL
1.076e-02	-4.53	Alpha_catenin	interpro domains	IPR001033	4	1	18521	50	CTNNA2
1.077e-02	-4.53	PLP	smart domains	SM00002	3	1	9717	35	GPM6A
1.077e-02	-4.53	MamL-1	smart domains	SM01275	3	1	9717	35	MAML2
1.077e-02	-4.53	Sorb	smart domains	SM00459	3	1	9717	35	SORBS1
1.092e-02	-4.52	Corticotropin Activation of Cortisol Production	SMPDB pathways	SMP0000310	5	1	1369	3	ADCY2
1.094e-02	-4.52	response to glycoside	biological process	GO:1903416	4	1	18204	50	ATP1A2
1.094e-02	-4.52	positive regulation of mesenchymal stem cell differentiation	biological process	GO:2000741	4	1	18204	50	SOX5
1.094e-02	-4.52	protein localization to secretory granule	biological process	GO:0033366	4	1	18204	50	CPE
1.094e-02	-4.52	N-glycan fucosylation	biological process	GO:0036071	4	1	18204	50	FUT9
1.094e-02	-4.52	regulation of amino acid uptake involved in synaptic transmission	biological process	GO:0051941	4	1	18204	50	ATP1A2
1.094e-02	-4.52	brain-derived neurotrophic factor receptor signaling pathway	biological process	GO:0031547	4	1	18204	50	NTRK2
1.094e-02	-4.52	ovarian cumulus expansion	biological process	GO:0001550	4	1	18204	50	BMPR1B
1.094e-02	-4.52	regulation of glutamate uptake involved in transmission of nerve impulse	biological process	GO:0051946	4	1	18204	50	ATP1A2
1.094e-02	-4.52	trans-synaptic signaling by BDNF	biological process	GO:0099191	4	1	18204	50	NTRK2
1.098e-02	-4.51	primitive_neuroectodermal_tumour-medulloblastoma	COSMIC cancer mutations	primitive_neuroectodermal_tumour-medulloblastoma	15350	49	16828	49	AQP4,NPAS3,NHSL1,GPC5,RFX4,PPP2R2B,SPARCL1,MACF1,GPM6A,MAML2,ZBTB20,NTM,MSI2,SLC1A3,SFXN5,CSGALNACT1,LSAMP,GLIS3,PARD3B,NFIA,DTNA,BMPR1B,SLC1A2,PITPNC1,ATP1A2,FMN2,ATP13A4,RYR3,NTRK2,SORBS1,TRPS1,PARD3,NEBL,ADCY2,CTNND2,SOX5,CPE,ITPR2,PTPRZ1,FBXL7,NKAIN3,FUT9,NRG3,MGAT4C,SLC4A4,RORA,TNIK,CDH20,ABLIM1
1.110e-02	-4.50	MYOD1 (myogenic differentiation 1)	protein interactions	4654	180	3	19454	50	RORA,NFIA,TRPS1
1.118e-02	-4.49	parathyroid-carcinoma	COSMIC cancer mutations	parathyroid-carcinoma	300	4	16828	49	TRPS1,GPC5,RYR3,MACF1
1.121e-02	-4.49	YWHAB (tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein beta)	protein interactions	7529	965	7	19454	50	NHSL1,MACF1,PARD3,PARD3B,ABLIM1,SORBS1,PITPNC1
1.138e-02	-4.48	head_neck	COSMIC cancer mutations	head_neck	15361	49	16828	49	CDH20,TNIK,RORA,SLC4A4,ABLIM1,MGAT4C,FBXL7,PTPRZ1,ITPR2,NRG3,FUT9,NKAIN3,NEBL,ADCY2,CPE,SOX5,CTNND2,PARD3,TRPS1,NTRK2,SORBS1,ATP13A4,RYR3,FMN2,PITPNC1,ATP1A2,PARD3B,DTNA,BMPR1B,SLC1A2,NFIA,GLIS3,LSAMP,CSGALNACT1,SFXN5,NTM,MSI2,ZBTB20,SLC1A3,GPM6A,MACF1,SPARCL1,MAML2,RFX4,GPC5,PPP2R2B,AQP4,NHSL1,NPAS3
1.143e-02	-4.47	human chr14q13.1	chromosome location	human chr14q13.1	6	1	26134	50	NPAS3
1.143e-02	-4.47	human chr4q34.2	chromosome location	human chr4q34.2	6	1	26134	50	GPM6A
1.144e-02	-4.47	PRPH (peripherin)	protein interactions	5630	182	3	19454	50	SORBS1,ABLIM1,PPP2R2B
1.145e-02	-4.47	establishment or maintenance of bipolar cell polarity	biological process	GO:0061245	59	2	18204	50	PARD3,PARD3B
1.145e-02	-4.47	endochondral bone morphogenesis	biological process	GO:0060350	59	2	18204	50	BMPR1B,CSGALNACT1
1.145e-02	-4.47	establishment or maintenance of apical/basal cell polarity	biological process	GO:0035088	59	2	18204	50	PARD3B,PARD3
1.145e-02	-4.47	YWHAG (tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein gamma)	protein interactions	7532	1211	8	19454	50	PITPNC1,SORBS1,ABLIM1,FMN2,MACF1,PARD3B,PARD3,NHSL1
1.147e-02	-4.47	Erythroid Transcription Factor GATA-1, subunit A	gene3d domains	3.30.50.10	56	2	14470	42	RORA,TRPS1
1.156e-02	-4.46	-	gene3d domains	1.20.58.1060	4	1	14470	42	MACF1
1.161e-02	-4.46	GSN (gelsolin)	protein interactions	2934	183	3	19454	50	PPP2R2B,DTNA,TNIK
1.167e-02	-4.45	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-peripheral_T_cell_lymphoma_unspecified	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-peripheral_T_cell_lymphoma_unspecified	162	3	16828	49	ITPR2,RYR3,MACF1
1.175e-02	-4.44	skeletal system development	biological process	GO:0001501	500	5	18204	50	NFIA,BMPR1B,TRPS1,CSGALNACT1,SOX5
1.178e-02	-4.44	cation binding	molecular function	GO:0043169	4341	19	18094	48	RORA,MACF1,ABLIM1,TRPS1,ATP1A2,SLC1A2,RYR3,SLC1A3,SPARCL1,CPE,GLIS3,ADCY2,ATP13A4,CSGALNACT1,MGAT4C,DTNA,BMPR1B,ZBTB20,ITPR2
1.179e-02	-4.44	SYNC (syncoilin, intermediate filament protein)	protein interactions	81493	64	2	19454	50	DTNA,MAML2
1.179e-02	-4.44	VSX1 (visual system homeobox 1)	protein interactions	30813	64	2	19454	50	NFIA,TRPS1
1.181e-02	-4.44	Apelin signaling pathway	KEGG pathways	hsa04371	138	3	7161	25	ADCY2,RYR3,ITPR2
1.182e-02	-4.44	regulation of glucose import	biological process	GO:0046324	60	2	18204	50	SORBS1,SLC1A2
1.182e-02	-4.44	export across plasma membrane	biological process	GO:0140115	60	2	18204	50	ATP1A2,SLC4A4
1.182e-02	-4.44	proteoglycan biosynthetic process	biological process	GO:0030166	60	2	18204	50	CSGALNACT1,BMPR1B
1.182e-02	-4.44	transmission of nerve impulse	biological process	GO:0019226	60	2	18204	50	NTRK2,ATP1A2
1.182e-02	-4.44	protein homotetramerization	biological process	GO:0051289	60	2	18204	50	RYR3,AQP4
1.184e-02	-4.44	cadherin binding	molecular function	GO:0045296	335	4	18094	48	CTNND2,MACF1,CDH20,CTNNA2
1.190e-02	-4.43	biliary_tract-gallbladder-carcinoma-adenocarcinoma	COSMIC cancer mutations	biliary_tract-gallbladder-carcinoma-adenocarcinoma	2821	15	16828	49	CTNND2,NHSL1,PITPNC1,NKAIN3,NRG3,ITPR2,RYR3,PTPRZ1,FMN2,SPARCL1,MACF1,PARD3,SLC4A4,TRPS1,TNIK
1.190e-02	-4.43	gallbladder	COSMIC cancer mutations	gallbladder	2821	15	16828	49	NRG3,NKAIN3,RYR3,FMN2,PTPRZ1,ITPR2,NHSL1,CTNND2,PITPNC1,TNIK,PARD3,SLC4A4,TRPS1,MACF1,SPARCL1
1.209e-02	-4.42	kidney	COSMIC cancer mutations	kidney	15380	49	16828	49	AQP4,NPAS3,NHSL1,RFX4,GPC5,PPP2R2B,GPM6A,MACF1,SPARCL1,MAML2,NTM,MSI2,ZBTB20,SLC1A3,SFXN5,LSAMP,CSGALNACT1,GLIS3,PARD3B,BMPR1B,DTNA,SLC1A2,NFIA,PITPNC1,ATP1A2,ATP13A4,RYR3,FMN2,NTRK2,SORBS1,PARD3,TRPS1,ADCY2,NEBL,CPE,SOX5,CTNND2,FBXL7,PTPRZ1,ITPR2,NRG3,FUT9,NKAIN3,MGAT4C,CDH20,TNIK,RORA,SLC4A4,ABLIM1
1.216e-02	-4.41	parathyroid	COSMIC cancer mutations	parathyroid	476	5	16828	49	GPC5,TRPS1,GPM6A,RYR3,MACF1
1.219e-02	-4.41	skin-arm-malignant_melanoma	COSMIC cancer mutations	skin-arm-malignant_melanoma	1308	9	16828	49	SLC4A4,TRPS1,ZBTB20,NTM,PARD3B,MACF1,ATP1A2,SORBS1,NPAS3
1.223e-02	-4.40	cellular response to organonitrogen compound	biological process	GO:0071417	505	5	18204	50	SORBS1,RYR3,ITPR2,SLC1A2,SLC1A3
1.223e-02	-4.40	monoatomic cation homeostasis	biological process	GO:0055080	505	5	18204	50	ATP13A4,ATP1A2,SLC1A3,RYR3,SLC4A4
1.240e-02	-4.39	cell migration	biological process	GO:0016477	921	7	18204	50	FMN2,NTRK2,NRG3,CDH20,GPM6A,CTNNA2,GPC5
1.248e-02	-4.38	HNF1B (HNF1 homeobox B)	protein interactions	6928	188	3	19454	50	NFIA,SOX5,TRPS1
1.249e-02	-4.38	central nervous system neuron differentiation	biological process	GO:0021953	176	3	18204	50	RORA,BMPR1B,NTRK2
1.250e-02	-4.38	MAML1 (mastermind like transcriptional coactivator 1)	protein interactions	9794	66	2	19454	50	MAML2,NFIA
1.253e-02	-4.38	SH3_9	pfam domains	PF14604	63	2	17795	48	SORBS1,NEBL
1.258e-02	-4.38	RORNUCRECPTR	prints domains	PR01293	3	1	5227	22	RORA
1.258e-02	-4.38	INSP3RECEPTR	prints domains	PR00779	3	1	5227	22	ITPR2
1.258e-02	-4.38	MYELINPLP	prints domains	PR00214	3	1	5227	22	GPM6A
1.258e-02	-4.38	NTKRECEPTOR	prints domains	PR01939	3	1	5227	22	NTRK2
1.258e-02	-4.38	RYANODINER	prints domains	PR00795	3	1	5227	22	RYR3
1.259e-02	-4.38	regulation of carbohydrate catabolic process	biological process	GO:0043470	62	2	18204	50	ZBTB20,SLC4A4
1.266e-02	-4.37	peripheral_T_cell_lymphoma_unspecified	COSMIC cancer mutations	peripheral_T_cell_lymphoma_unspecified	167	3	16828	49	ITPR2,MACF1,RYR3
1.279e-02	-4.36	Rab38 (RAB38, member RAS oncogene family)	protein interactions	72433	5	1	19454	50	BMPR1B
1.279e-02	-4.36	Rab6b (RAB6B, member RAS oncogene family)	protein interactions	270192	5	1	19454	50	BMPR1B
1.279e-02	-4.36	RFX4 (regulatory factor X4)	protein interactions	5992	5	1	19454	50	RFX4
1.279e-02	-4.36	Rhobtb1 (Rho-related BTB domain containing 1)	protein interactions	69288	5	1	19454	50	BMPR1B
1.279e-02	-4.36	Rhoj (ras homolog family member J)	protein interactions	80837	5	1	19454	50	BMPR1B
1.279e-02	-4.36	TRH (thyrotropin releasing hormone)	protein interactions	7200	5	1	19454	50	CPE
1.279e-02	-4.36	Cdk4 (cyclin dependent kinase 4)	protein interactions	12567	5	1	19454	50	BMPR1B
1.279e-02	-4.36	SLC10A3 (solute carrier family 10 member 3)	protein interactions	8273	5	1	19454	50	SORBS1
1.279e-02	-4.36	Rras2 (related RAS viral (r-ras) oncogene 2)	protein interactions	66922	5	1	19454	50	BMPR1B
1.279e-02	-4.36	Wwp2 (WW domain containing E3 ubiquitin protein ligase 2)	protein interactions	66894	5	1	19454	50	GLIS3
1.282e-02	-4.36	regulation of small molecule metabolic process	biological process	GO:0062012	331	4	18204	50	RORA,SLC4A4,SORBS1,ZBTB20
1.310e-02	-4.34	Intracellular Signalling Through PGD2 receptor and Prostaglandin D2	SMPDB pathways	SMP0000343	6	1	1369	3	ADCY2
1.310e-02	-4.34	Dopamine Activation of Neurological Reward System	SMPDB pathways	SMP0000308	6	1	1369	3	ADCY2
1.314e-02	-4.33	inorganic ion transmembrane transport	biological process	GO:0098660	715	6	18204	50	ATP1A2,SLC1A3,ITPR2,RYR3,SLC4A4,GPM6A
1.317e-02	-4.33	carboxylic acid transmembrane transporter activity	molecular function	GO:0046943	186	3	18094	48	SFXN5,SLC1A2,SLC1A3
1.318e-02	-4.33	main axon	cellular component	GO:0044304	68	2	19108	49	SLC1A2,PARD3
1.320e-02	-4.33	neurotrophin receptor activity	molecular function	GO:0005030	5	1	18094	48	NTRK2
1.320e-02	-4.33	transforming growth factor beta receptor activity, type I	molecular function	GO:0005025	5	1	18094	48	BMPR1B
1.322e-02	-4.33	monoatomic ion homeostasis	biological process	GO:0050801	515	5	18204	50	ATP1A2,SLC1A3,ATP13A4,RYR3,SLC4A4
1.324e-02	-4.32	PLCH1 (phospholipase C eta 1)	protein interactions	23007	68	2	19454	50	NTRK2,PARD3
1.325e-02	-4.32	Adrenergic signaling in cardiomyocytes	KEGG pathways	ko04261	144	3	7161	25	ATP1A2,ADCY2,PPP2R2B
1.325e-02	-4.32	Adrenergic signaling in cardiomyocytes	KEGG pathways	hsa04261	144	3	7161	25	PPP2R2B,ADCY2,ATP1A2
1.326e-02	-4.32	terminal O-glycans residues modification	BIOCYC pathways	META_PWY-7434	4	1	902	3	FUT9
1.327e-02	-4.32	L-amino acid transmembrane transporter activity	molecular function	GO:0015179	66	2	18094	48	SLC1A3,SLC1A2
1.335e-02	-4.32	glycoprotein metabolic process	biological process	GO:0009100	335	4	18204	50	CSGALNACT1,BMPR1B,MGAT4C,FUT9
1.335e-02	-4.32	camera-type eye development	biological process	GO:0043010	335	4	18204	50	BMPR1B,NTRK2,NFIA,GPM6A
1.336e-02	-4.32	organic acid transmembrane transporter activity	molecular function	GO:0005342	187	3	18094	48	SLC1A2,SFXN5,SLC1A3
1.337e-02	-4.31	actin filament bundle assembly	biological process	GO:0051017	64	2	18204	50	FMN2,SORBS1
1.337e-02	-4.31	dendrite morphogenesis	biological process	GO:0048813	64	2	18204	50	CTNNA2,CTNND2
1.339e-02	-4.31	POF1B (POF1B actin binding protein)	protein interactions	79983	193	3	19454	50	CSGALNACT1,PPP2R2B,NKAIN3
1.339e-02	-4.31	CTF_NFI_2	prosite domains	PS51080	4	1	12186	41	NFIA
1.339e-02	-4.31	PR55_2	prosite domains	PS01025	4	1	12186	41	PPP2R2B
1.339e-02	-4.31	NEBULIN	prosite domains	PS51216	4	1	12186	41	NEBL
1.339e-02	-4.31	CTF_NFI_1	prosite domains	PS00349	4	1	12186	41	NFIA
1.339e-02	-4.31	PR55_1	prosite domains	PS01024	4	1	12186	41	PPP2R2B
1.342e-02	-4.31	IP_trans	pfam domains	PF02121	5	1	17795	48	PITPNC1
1.342e-02	-4.31	SFXNs	pfam domains	PF03820	5	1	17795	48	SFXN5
1.342e-02	-4.31	Vinculin	pfam domains	PF01044	5	1	17795	48	CTNNA2
1.342e-02	-4.31	FOLN	pfam domains	PF09289	5	1	17795	48	SPARCL1
1.343e-02	-4.31	PI_transfer	interpro domains	IPR001666	5	1	18521	50	PITPNC1
1.343e-02	-4.31	Vinculin/catenin	interpro domains	IPR006077	5	1	18521	50	CTNNA2
1.343e-02	-4.31	Mtc	interpro domains	IPR004686	5	1	18521	50	SFXN5
1.343e-02	-4.31	P-type_TPase_V	interpro domains	IPR006544	5	1	18521	50	ATP13A4
1.343e-02	-4.31	Follistatin/Osteonectin_EGF	interpro domains	IPR015369	5	1	18521	50	SPARCL1
1.343e-02	-4.31	Na/HCO3_transpt	interpro domains	IPR003024	5	1	18521	50	SLC4A4
1.352e-02	-4.30	NS-malignant_melanoma	COSMIC cancer mutations	NS-malignant_melanoma	3420	17	16828	49	PARD3,MACF1,GLIS3,MGAT4C,GPC5,ITPR2,ATP13A4,FMN2,PTPRZ1,RFX4,FUT9,NRG3,NEBL,ADCY2,PITPNC1,CTNND2,ATP1A2
1.354e-02	-4.30	NGF-independant TRKA activation	REACTOME pathways	R-HSA-187024	5	1	10285	28	NTRK2
1.356e-02	-4.30	arm	COSMIC cancer mutations	arm	1331	9	16828	49	MACF1,NPAS3,SORBS1,ATP1A2,PARD3B,NTM,TRPS1,SLC4A4,ZBTB20
1.363e-02	-4.30	temporoparietal	COSMIC cancer mutations	temporoparietal	61	2	16828	49	PARD3,RYR3
1.366e-02	-4.29	citrate transport	biological process	GO:0015746	5	1	18204	50	SFXN5
1.366e-02	-4.29	negative regulation of chondrocyte proliferation	biological process	GO:1902731	5	1	18204	50	BMPR1B
1.366e-02	-4.29	polar body extrusion after meiotic divisions	biological process	GO:0040038	5	1	18204	50	FMN2
1.366e-02	-4.29	amygdala development	biological process	GO:0021764	5	1	18204	50	ATP1A2
1.366e-02	-4.29	synaptic signaling via neuropeptide	biological process	GO:0099538	5	1	18204	50	NTRK2
1.366e-02	-4.29	tricarboxylic acid transport	biological process	GO:0006842	5	1	18204	50	SFXN5
1.367e-02	-4.29	neoplasm	COSMIC cancer mutations	neoplasm	14787	48	16828	49	BMPR1B,DTNA,SLC1A2,NFIA,PARD3B,GLIS3,LSAMP,CSGALNACT1,SFXN5,SLC1A3,NTM,MSI2,ZBTB20,MAML2,GPM6A,MACF1,SPARCL1,PPP2R2B,RFX4,GPC5,NHSL1,NPAS3,AQP4,ABLIM1,TNIK,CDH20,RORA,SLC4A4,MGAT4C,FUT9,NRG3,NKAIN3,FBXL7,PTPRZ1,ITPR2,CPE,SOX5,CTNND2,ADCY2,NEBL,PARD3,TRPS1,SORBS1,NTRK2,ATP13A4,RYR3,FMN2,ATP1A2
1.375e-02	-4.29	skin-upper_back-malignant_melanoma	COSMIC cancer mutations	skin-upper_back-malignant_melanoma	319	4	16828	49	GPC5,PARD3B,MACF1,FUT9
1.399e-02	-4.27	PCDH20 (protocadherin 20)	protein interactions	64881	70	2	19454	50	CTNNA2,MGAT4C
1.399e-02	-4.27	cellular component assembly	biological process	GO:0022607	2472	13	18204	50	ABLIM1,RFX4,FMN2,NRG3,NEBL,RYR3,TNIK,SLC1A2,CDH20,PARD3,GPM6A,SORBS1,AQP4
1.400e-02	-4.27	adenoma	COSMIC cancer mutations	adenoma	2873	15	16828	49	RYR3,PTPRZ1,GPC5,NEBL,ADCY2,NPAS3,SOX5,CTNND2,CDH20,PARD3,ZBTB20,BMPR1B,GPM6A,NTRK2,MACF1
1.403e-02	-4.27	bone-extraskeletal-Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour	COSMIC cancer mutations	bone-extraskeletal-Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour	891	7	16828	49	SPARCL1,ATP1A2,NPAS3,ITPR2,PTPRZ1,PPP2R2B,ABLIM1
1.407e-02	-4.26	RAB35 (RAB35, member RAS oncogene family)	protein interactions	11021	559	5	19454	50	DTNA,MACF1,PARD3,SLC1A3,FMN2
1.412e-02	-4.26	membrane protein complex	cellular component	GO:0098796	1261	8	19108	49	RYR3,CDH20,BMPR1B,ATP1A2,SLC1A3,CTNNA2,SORBS1,SLC1A2
1.418e-02	-4.26	liver-carcinoma-hepatocellular_carcinoma	COSMIC cancer mutations	liver-carcinoma-hepatocellular_carcinoma	14800	48	16828	49	TRPS1,PARD3,NTRK2,SORBS1,FMN2,RYR3,ATP13A4,PITPNC1,ATP1A2,CDH20,TNIK,SLC4A4,RORA,ABLIM1,MGAT4C,PTPRZ1,FBXL7,ITPR2,NRG3,FUT9,NKAIN3,ADCY2,NEBL,CPE,CTNND2,SOX5,NTM,ZBTB20,SLC1A3,MACF1,GPM6A,SPARCL1,MAML2,RFX4,GPC5,PPP2R2B,AQP4,NPAS3,NHSL1,PARD3B,NFIA,DTNA,BMPR1B,SLC1A2,GLIS3,LSAMP,CSGALNACT1,SFXN5
1.418e-02	-4.26	hepatocellular_carcinoma	COSMIC cancer mutations	hepatocellular_carcinoma	14800	48	16828	49	SFXN5,CSGALNACT1,LSAMP,GLIS3,DTNA,SLC1A2,BMPR1B,NFIA,PARD3B,NHSL1,NPAS3,AQP4,PPP2R2B,GPC5,RFX4,MAML2,SPARCL1,GPM6A,MACF1,SLC1A3,ZBTB20,NTM,SOX5,CTNND2,CPE,ADCY2,NEBL,NKAIN3,NRG3,FUT9,ITPR2,FBXL7,PTPRZ1,MGAT4C,ABLIM1,RORA,SLC4A4,TNIK,CDH20,ATP1A2,PITPNC1,RYR3,ATP13A4,FMN2,SORBS1,NTRK2,PARD3,TRPS1
1.418e-02	-4.26	L-alpha-amino acid transmembrane transport	biological process	GO:1902475	66	2	18204	50	SLC1A2,SLC1A3
1.433e-02	-4.25	NEBU	smart domains	SM00227	4	1	9717	35	NEBL
1.433e-02	-4.25	NFIX (nuclear factor I X)	protein interactions	4784	198	3	19454	50	NFIA,TRPS1,SOX5
1.435e-02	-4.24	small_intestine-carcinoid-endocrine_tumour	COSMIC cancer mutations	small_intestine-carcinoid-endocrine_tumour	175	3	16828	49	CSGALNACT1,TNIK,MACF1
1.437e-02	-4.24	AKR7L (aldo-keto reductase family 7 like (gene/pseudogene))	protein interactions	246181	71	2	19454	50	PARD3,MACF1
1.437e-02	-4.24	ANK2 (ankyrin 2)	protein interactions	287	71	2	19454	50	GPM6A,TNIK
1.437e-02	-4.24	CRYBG1 (crystallin beta-gamma domain containing 1)	protein interactions	202	71	2	19454	50	SPARCL1,CSGALNACT1
1.437e-02	-4.24	HEPHL1 (hephaestin like 1)	protein interactions	341208	71	2	19454	50	CSGALNACT1,PPP2R2B
1.451e-02	-4.23	NTRK3 (neurotrophic receptor tyrosine kinase 3)	protein interactions	4916	367	4	19454	50	ABLIM1,TNIK,NTRK2,PARD3
1.476e-02	-4.22	DPYSL3 (dihydropyrimidinase like 3)	protein interactions	1809	72	2	19454	50	GPM6A,TNIK
1.476e-02	-4.22	PPP3CC (protein phosphatase 3 catalytic subunit gamma)	protein interactions	5533	72	2	19454	50	BMPR1B,PARD3B
1.476e-02	-4.22	Ppp1cb (protein phosphatase 1 catalytic subunit beta)	protein interactions	19046	72	2	19454	50	ABLIM1,PARD3
1.490e-02	-4.21	LIM	pfam domains	PF00412	69	2	17795	48	ABLIM1,NEBL
1.501e-02	-4.20	actin filament bundle organization	biological process	GO:0061572	68	2	18204	50	FMN2,SORBS1
1.501e-02	-4.20	extraskeletal	COSMIC cancer mutations	extraskeletal	903	7	16828	49	ABLIM1,PPP2R2B,PTPRZ1,ITPR2,NPAS3,ATP1A2,SPARCL1
1.508e-02	-4.19	upper_back	COSMIC cancer mutations	upper_back	328	4	16828	49	FUT9,GPC5,MACF1,PARD3B
1.512e-02	-4.19	FEV (FEV transcription factor, ETS family member)	protein interactions	54738	202	3	19454	50	SOX5,TRPS1,NFIA
1.520e-02	-4.19	skin-scalp-carcinoma-squamous_cell_carcinoma	COSMIC cancer mutations	skin-scalp-carcinoma-squamous_cell_carcinoma	1596	10	16828	49	SOX5,ATP1A2,MACF1,LSAMP,ATP13A4,PTPRZ1,RORA,SLC4A4,GPC5,TRPS1
1.524e-02	-4.18	adrenal_gland	COSMIC cancer mutations	adrenal_gland	2628	14	16828	49	NHSL1,SOX5,CTNND2,ATP1A2,ADCY2,NRG3,CSGALNACT1,RFX4,FMN2,PTPRZ1,MAML2,NTRK2,SLC1A2,ZBTB20
1.526e-02	-4.18	positive regulation of multicellular organismal process	biological process	GO:0051240	1691	10	18204	50	RORA,ZBTB20,SFXN5,MACF1,PARD3,SOX5,BMPR1B,PTPRZ1,ATP1A2,NTRK2
1.527e-02	-4.18	Vasopressin Regulation of Water Homeostasis	SMPDB pathways	SMP0000322	7	1	1369	3	ADCY2
1.529e-02	-4.18	PAR polarity complex	cellular component	GO:0120157	6	1	19108	49	PARD3
1.531e-02	-4.18	Oxytocin signaling pathway	KEGG pathways	hsa04921	152	3	7161	25	RYR3,ADCY2,ITPR2
1.531e-02	-4.18	Oxytocin signaling pathway	KEGG pathways	ko04921	152	3	7161	25	ITPR2,ADCY2,RYR3
1.532e-02	-4.18	Zbtb2 (zinc finger and BTB domain containing 2)	protein interactions	381990	6	1	19454	50	SORBS1
1.532e-02	-4.18	GDF6 (growth differentiation factor 6)	protein interactions	392255	6	1	19454	50	BMPR1B
1.532e-02	-4.18	Tiam2 (T cell lymphoma invasion and metastasis 2)	protein interactions	24001	6	1	19454	50	DTNA
1.532e-02	-4.18	Fancl (Fanconi anemia, complementation group L)	protein interactions	67030	6	1	19454	50	BMPR1B
1.532e-02	-4.18	ADCY1 (adenylate cyclase 1)	protein interactions	107	6	1	19454	50	ADCY2
1.532e-02	-4.18	SOX11 (SRY-box transcription factor 11)	protein interactions	6664	6	1	19454	50	SOX5
1.532e-02	-4.18	CYRIA (CYFIP related Rac1 interactor A)	protein interactions	81553	6	1	19454	50	GPM6A
1.532e-02	-4.18	DRP2 (dystrophin related protein 2)	protein interactions	1821	6	1	19454	50	DTNA
1.532e-02	-4.18	Map2k3 (mitogen-activated protein kinase kinase 3)	protein interactions	26397	6	1	19454	50	BMPR1B
1.532e-02	-4.18	TPPP3 (tubulin polymerization promoting protein family member 3)	protein interactions	51673	6	1	19454	50	PPP2R2B
1.532e-02	-4.18	SLC12A5 (solute carrier family 12 member 5)	protein interactions	57468	6	1	19454	50	GPM6A
1.532e-02	-4.18	Itch (itchy, E3 ubiquitin protein ligase)	protein interactions	16396	6	1	19454	50	GLIS3
1.532e-02	-4.18	SOX1 (SRY-box transcription factor 1)	protein interactions	6656	6	1	19454	50	SOX5
1.532e-02	-4.18	Rhod (ras homolog family member D)	protein interactions	11854	6	1	19454	50	BMPR1B
1.541e-02	-4.17	GJA1 (gap junction protein alpha 1)	protein interactions	2697	572	5	19454	50	TNIK,DTNA,ITPR2,MACF1,PARD3
1.552e-02	-4.17	NFIC (nuclear factor I C)	protein interactions	4782	204	3	19454	50	TRPS1,SOX5,NFIA
1.552e-02	-4.17	CASK (calcium/calmodulin dependent serine protein kinase)	protein interactions	8573	204	3	19454	50	PARD3B,DTNA,ABLIM1
1.576e-02	-4.15	Znf_LIM	interpro domains	IPR001781	71	2	18521	50	ABLIM1,NEBL
1.581e-02	-4.15	calcium-induced calcium release activity	molecular function	GO:0048763	6	1	18094	48	RYR3
1.581e-02	-4.15	steroid hormone binding	molecular function	GO:1990239	6	1	18094	48	ATP1A2
1.581e-02	-4.15	glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity	molecular function	GO:0047238	6	1	18094	48	CSGALNACT1
1.581e-02	-4.15	4-galactosyl-N-acetylglucosaminide 3-alpha-L-fucosyltransferase activity	molecular function	GO:0017083	6	1	18094	48	FUT9
1.581e-02	-4.15	sodium:bicarbonate symporter activity	molecular function	GO:0008510	6	1	18094	48	SLC4A4
1.592e-02	-4.14	cellular process	biological process	GO:0009987	14996	47	18204	50	NFIA,CTNNA2,NTRK2,GLIS3,SLC4A4,AQP4,CPE,ADCY2,MACF1,MAML2,ATP1A2,PARD3B,SOX5,FBXL7,FUT9,ITPR2,GPC5,PARD3,MSI2,TNIK,CSGALNACT1,ZBTB20,RFX4,ABLIM1,LSAMP,ATP13A4,SPARCL1,FMN2,NEBL,NRG3,PTPRZ1,DTNA,SLC1A3,MGAT4C,GPM6A,SFXN5,PITPNC1,SLC1A2,BMPR1B,CTNND2,NTM,RORA,RYR3,NHSL1,CDH20,PPP2R2B,SORBS1
1.597e-02	-4.14	Synaptic Vesicle Pathway	WikiPathways	WP2267	52	2	5310	20	ATP1A2,SLC1A3
1.600e-02	-4.13	other	COSMIC cancer mutations	other	14843	48	16828	49	TRPS1,PARD3,SORBS1,NTRK2,FMN2,ATP13A4,RYR3,ATP1A2,ABLIM1,SLC4A4,RORA,TNIK,CDH20,MGAT4C,NKAIN3,FUT9,NRG3,ITPR2,PTPRZ1,FBXL7,CTNND2,SOX5,CPE,ADCY2,NEBL,SLC1A3,ZBTB20,MSI2,NTM,MAML2,SPARCL1,MACF1,GPM6A,PPP2R2B,GPC5,RFX4,NPAS3,NHSL1,AQP4,NFIA,BMPR1B,SLC1A2,DTNA,PARD3B,GLIS3,CSGALNACT1,LSAMP,SFXN5
1.608e-02	-4.13	Glypican	pfam domains	PF01153	6	1	17795	48	GPC5
1.608e-02	-4.13	GAS2	pfam domains	PF02187	6	1	17795	48	MACF1
1.608e-02	-4.13	EF-hand_2	pfam domains	PF09068	6	1	17795	48	DTNA
1.608e-02	-4.13	SH3_10	pfam domains	PF17902	6	1	17795	48	MACF1
1.608e-02	-4.13	Adcy_cons_dom	pfam domains	PF06327	6	1	17795	48	ADCY2
1.608e-02	-4.13	EF-hand_3	pfam domains	PF09069	6	1	17795	48	DTNA
1.608e-02	-4.13	Plectin	pfam domains	PF00681	6	1	17795	48	MACF1
1.609e-02	-4.13	P-type_ATPase_IIC	interpro domains	IPR005775	6	1	18521	50	ATP1A2
1.609e-02	-4.13	GAR_dom_sf	interpro domains	IPR036534	6	1	18521	50	MACF1
1.609e-02	-4.13	Desmoplakin_SH3	interpro domains	IPR041615	6	1	18521	50	MACF1
1.609e-02	-4.13	GLI-like	interpro domains	IPR043359	6	1	18521	50	GLIS3
1.609e-02	-4.13	EF-hand_dom_typ1	interpro domains	IPR015153	6	1	18521	50	DTNA
1.609e-02	-4.13	Glypican_CS	interpro domains	IPR019803	6	1	18521	50	GPC5
1.609e-02	-4.13	GAR_dom	interpro domains	IPR003108	6	1	18521	50	MACF1
1.609e-02	-4.13	Glypican	interpro domains	IPR001863	6	1	18521	50	GPC5
1.609e-02	-4.13	Adcy_conserved_dom	interpro domains	IPR009398	6	1	18521	50	ADCY2
1.609e-02	-4.13	EF-hand_dom_typ2	interpro domains	IPR015154	6	1	18521	50	DTNA
1.616e-02	-4.13	bone-femur-other-chondroblastoma	COSMIC cancer mutations	bone-femur-other-chondroblastoma	183	3	16828	49	NRG3,GPC5,RYR3
1.618e-02	-4.12	protein homooligomerization	biological process	GO:0051260	194	3	18204	50	SLC1A2,RYR3,AQP4
1.623e-02	-4.12	Activation of TRKA receptors	REACTOME pathways	R-HSA-187015	6	1	10285	28	NTRK2
1.627e-02	-4.12	sarcoplasmic reticulum	cellular component	GO:0016529	76	2	19108	49	RYR3,ITPR2
1.637e-02	-4.11	fused antrum stage	biological process	GO:0048165	6	1	18204	50	BMPR1B
1.637e-02	-4.11	intracellular water homeostasis	biological process	GO:0009992	6	1	18204	50	AQP4
1.637e-02	-4.11	establishment of meiotic spindle localization	biological process	GO:0051295	6	1	18204	50	FMN2
1.637e-02	-4.11	asymmetric neuroblast division	biological process	GO:0055059	6	1	18204	50	SOX5
1.637e-02	-4.11	gamma-aminobutyric acid biosynthetic process	biological process	GO:0009449	6	1	18204	50	SLC1A3
1.637e-02	-4.11	ERBB4-ERBB4 signaling pathway	biological process	GO:0038138	6	1	18204	50	NRG3
1.637e-02	-4.11	mammary gland formation	biological process	GO:0060592	6	1	18204	50	NRG3
1.640e-02	-4.11	hexosyltransferase activity	molecular function	GO:0016758	202	3	18094	48	MGAT4C,CSGALNACT1,FUT9
1.653e-02	-4.10	carbohydrate derivative metabolic process	biological process	GO:1901135	975	7	18204	50	ADCY2,FUT9,MGAT4C,RORA,ATP1A2,BMPR1B,CSGALNACT1
1.656e-02	-4.10	chondroitin biosynthesis	BIOCYC pathways	META_PWY-6566	5	1	902	3	CSGALNACT1
1.670e-02	-4.09	KIF20A (kinesin family member 20A)	protein interactions	10112	1044	7	19454	50	MACF1,PARD3,NEBL,MSI2,ITPR2,ABLIM1,RORA
1.672e-02	-4.09	protein N-linked glycosylation	biological process	GO:0006487	72	2	18204	50	FUT9,MGAT4C
1.672e-02	-4.09	regulation of ATP metabolic process	biological process	GO:1903578	72	2	18204	50	SLC4A4,ZBTB20
1.673e-02	-4.09	ALPHACATENIN	prints domains	PR00805	4	1	5227	22	CTNNA2
1.673e-02	-4.09	PP2APR55	prints domains	PR00600	4	1	5227	22	PPP2R2B
1.675e-02	-4.09	ABI1 (abl interactor 1)	protein interactions	10006	210	3	19454	50	NHSL1,SLC1A3,SORBS1
1.676e-02	-4.09	ADGRL2 (adhesion G protein-coupled receptor L2)	protein interactions	23266	77	2	19454	50	PARD3,NTRK2
1.677e-02	-4.09	cellular response to organic substance	biological process	GO:0071310	1716	10	18204	50	AQP4,SORBS1,ATP1A2,SLC1A2,RYR3,RORA,ZBTB20,SLC1A3,ADCY2,ITPR2
1.694e-02	-4.08	signal transduction	biological process	GO:0007165	4637	20	18204	50	ADCY2,CTNND2,CPE,NFIA,NRG3,FMN2,NTRK2,ATP1A2,MAML2,MACF1,SPARCL1,ITPR2,DTNA,RORA,RYR3,BMPR1B,TNIK,PITPNC1,SORBS1,PARD3
1.705e-02	-4.07	HAD_sf	interpro domains	IPR023214	74	2	18521	50	ATP1A2,ATP13A4
1.709e-02	-4.07	human chr4q22.3	chromosome location	human chr4q22.3	9	1	26134	50	BMPR1B
1.711e-02	-4.07	positive regulation of cell projection organization	biological process	GO:0031346	361	4	18204	50	MACF1,GPM6A,NTRK2,FUT9
1.716e-02	-4.07	peptide metabolic process	biological process	GO:0006518	73	2	18204	50	SLC1A2,CPE
1.717e-02	-4.06	ATP2B3 (ATPase plasma membrane Ca2+ transporting 3)	protein interactions	492	78	2	19454	50	CSGALNACT1,GPM6A
1.717e-02	-4.06	ANKRD40 (ankyrin repeat domain 40)	protein interactions	91369	78	2	19454	50	MSI2,SOX5
1.717e-02	-4.06	Nedd4 (NEDD4 E3 ubiquitin protein ligase)	protein interactions	25489	78	2	19454	50	BMPR1B,NTRK2
1.729e-02	-4.06	Plakin repeat	gene3d domains	3.90.1290.10	6	1	14470	42	MACF1
1.729e-02	-4.06	Gas2-like domain	gene3d domains	3.30.920.20	6	1	14470	42	MACF1
1.735e-02	-4.05	autonomic_ganglia-paraganglioma-benign	COSMIC cancer mutations	autonomic_ganglia-paraganglioma-benign	6	1	16828	49	NHSL1
1.744e-02	-4.05	Intracellular Signalling Through Prostacyclin Receptor and Prostacyclin	SMPDB pathways	SMP0000354	8	1	1369	3	ADCY2
1.759e-02	-4.04	PRDM1 (PR/SET domain 1)	protein interactions	639	79	2	19454	50	NFIA,TRPS1
1.761e-02	-4.04	NCK1 (NCK adaptor protein 1)	protein interactions	4690	214	3	19454	50	NTRK2,TNIK,NHSL1
1.768e-02	-4.04	ovary-carcinoma	COSMIC cancer mutations	ovary-carcinoma	933	7	16828	49	TNIK,ITPR2,PPP2R2B,BMPR1B,MACF1,NTRK2,ATP1A2
1.786e-02	-4.03	Smurf1 (SMAD specific E3 ubiquitin protein ligase 1)	protein interactions	75788	7	1	19454	50	GLIS3
1.786e-02	-4.03	SASH3 (SAM and SH3 domain containing 3)	protein interactions	54440	7	1	19454	50	BMPR1B
1.786e-02	-4.03	Fbxo3 (F-box protein 3)	protein interactions	57443	7	1	19454	50	BMPR1B
1.786e-02	-4.03	Uhmk1 (U2AF homology motif (UHM) kinase 1)	protein interactions	16589	7	1	19454	50	BMPR1B
1.786e-02	-4.03	Smad7 (SMAD family member 7)	protein interactions	17131	7	1	19454	50	BMPR1B
1.786e-02	-4.03	SLC16A5 (solute carrier family 16 member 5)	protein interactions	9121	7	1	19454	50	PTPRZ1
1.786e-02	-4.03	ABCC12 (ATP binding cassette subfamily C member 12)	protein interactions	94160	7	1	19454	50	NPAS3
1.786e-02	-4.03	ZBTB45 (zinc finger and BTB domain containing 45)	protein interactions	84878	7	1	19454	50	ZBTB20
1.786e-02	-4.03	RGMB (repulsive guidance molecule BMP co-receptor b)	protein interactions	285704	7	1	19454	50	BMPR1B
1.790e-02	-4.02	axonogenesis	biological process	GO:0007409	366	4	18204	50	CTNNA2,PARD3,BMPR1B,PTPRZ1
1.796e-02	-4.02	cellular component organization	biological process	GO:0016043	5636	23	18204	50	GPM6A,AQP4,PITPNC1,BMPR1B,SLC1A2,SPARCL1,CTNNA2,FMN2,PTPRZ1,NEBL,NRG3,NFIA,RFX4,ABLIM1,PARD3,CDH20,SORBS1,CSGALNACT1,TNIK,RYR3,MACF1,PARD3B,CTNND2
1.802e-02	-4.02	Calcium Regulation in the Cardiac Cell	WikiPathways	WP536	151	3	5310	20	ADCY2,RYR3,ITPR2
1.826e-02	-4.00	GFAP (glial fibrillary acidic protein)	protein interactions	2670	217	3	19454	50	NKAIN3,RORA,ABLIM1
1.836e-02	-4.00	plasma membrane protein complex	cellular component	GO:0098797	600	5	19108	49	ATP1A2,SORBS1,BMPR1B,CTNNA2,CDH20
1.843e-02	-3.99	P-type sodium:potassium-exchanging transporter activity	molecular function	GO:0005391	7	1	18094	48	ATP1A2
1.843e-02	-3.99	P-type sodium transporter activity	molecular function	GO:0008554	7	1	18094	48	ATP1A2
1.843e-02	-3.99	phosphatidic acid transfer activity	molecular function	GO:1990050	7	1	18094	48	PITPNC1
1.843e-02	-3.99	SOX17 (SRY-box transcription factor 17)	protein interactions	64321	81	2	19454	50	TRPS1,NFIA
1.844e-02	-3.99	cGMP-PKG signaling pathway	KEGG pathways	ko04022	163	3	7161	25	ATP1A2,ADCY2,ITPR2
1.844e-02	-3.99	cGMP-PKG signaling pathway	KEGG pathways	hsa04022	163	3	7161	25	ITPR2,ATP1A2,ADCY2
1.865e-02	-3.98	Ion channel transport	REACTOME pathways	R-HSA-983712	209	3	10285	28	ATP13A4,ATP1A2,RYR3
1.872e-02	-3.98	calcium ion transmembrane transport	biological process	GO:0070588	205	3	18204	50	GPM6A,RYR3,ITPR2
1.873e-02	-3.98	SPARC_Ca_bdg	pfam domains	PF10591	7	1	17795	48	SPARCL1
1.873e-02	-3.98	TGF_beta_GS	pfam domains	PF08515	7	1	17795	48	BMPR1B
1.875e-02	-3.98	Aquaporin_transptr	interpro domains	IPR034294	7	1	18521	50	AQP4
1.875e-02	-3.98	Plakophilin/d_Catenin	interpro domains	IPR028435	7	1	18521	50	CTNND2
1.875e-02	-3.98	Plectin_repeat	interpro domains	IPR001101	7	1	18521	50	MACF1
1.875e-02	-3.98	Plakin_repeat_sf	interpro domains	IPR035915	7	1	18521	50	MACF1
1.875e-02	-3.98	GS_dom	interpro domains	IPR003605	7	1	18521	50	BMPR1B
1.875e-02	-3.98	SPARC/Testican_Ca-bd-dom	interpro domains	IPR019577	7	1	18521	50	SPARCL1
1.875e-02	-3.98	Alpha-catenin/vinculin-like_sf	interpro domains	IPR036723	7	1	18521	50	CTNNA2
1.882e-02	-3.97	HAD-like_sf	interpro domains	IPR036412	78	2	18521	50	ATP13A4,ATP1A2
1.891e-02	-3.97	system process	biological process	GO:0003008	2015	11	18204	50	CTNNA2,PTPRZ1,NTRK2,ATP1A2,ABLIM1,AQP4,SLC1A2,RYR3,SLC4A4,DTNA,SLC1A3
1.897e-02	-3.96	human chr12p11.23	chromosome location	human chr12p11.23	10	1	26134	50	ITPR2
1.897e-02	-3.96	human chr9p24.2	chromosome location	human chr9p24.2	10	1	26134	50	GLIS3
1.898e-02	-3.96	BMP signaling pathway	biological process	GO:0030509	77	2	18204	50	NFIA,BMPR1B
1.898e-02	-3.96	positive regulation of axonogenesis	biological process	GO:0050772	77	2	18204	50	NTRK2,MACF1
1.898e-02	-3.96	neural retina development	biological process	GO:0003407	77	2	18204	50	GPM6A,NTRK2
1.898e-02	-3.96	Cysteine Rich Protein	gene3d domains	2.10.110.10	73	2	14470	42	ABLIM1,NEBL
1.907e-02	-3.96	regulation of oligodendrocyte progenitor proliferation	biological process	GO:0070445	7	1	18204	50	PTPRZ1
1.907e-02	-3.96	parallel actin filament bundle assembly	biological process	GO:0030046	7	1	18204	50	FMN2
1.907e-02	-3.96	chromosome movement towards spindle pole	biological process	GO:0051305	7	1	18204	50	FMN2
1.907e-02	-3.96	negative regulation of Arp2/3 complex-mediated actin nucleation	biological process	GO:0034316	7	1	18204	50	CTNNA2
1.907e-02	-3.96	positive regulation of transcription of Notch receptor target	biological process	GO:0007221	7	1	18204	50	MAML2
1.907e-02	-3.96	interneuron migration from the subpallium to the cortex	biological process	GO:0021830	7	1	18204	50	NRG3
1.907e-02	-3.96	cellular response to magnesium ion	biological process	GO:0071286	7	1	18204	50	RYR3
1.907e-02	-3.96	glial cell fate specification	biological process	GO:0021780	7	1	18204	50	NFIA
1.921e-02	-3.95	caveola	cellular component	GO:0005901	83	2	19108	49	SORBS1,ATP1A2
1.930e-02	-3.95	PAX2 (paired box 2)	protein interactions	5076	83	2	19454	50	TRPS1,NFIA
1.943e-02	-3.94	stomach-carcinoma-mixed_intestinal_and_diffuse_adenocarcinoma-unclassifiable	COSMIC cancer mutations	stomach-carcinoma-mixed_intestinal_and_diffuse_adenocarcinoma-unclassifiable	951	7	16828	49	SLC1A2,ITPR2,GPC5,PARD3,FMN2,ATP13A4,MACF1
1.943e-02	-3.94	mixed_intestinal_and_diffuse_adenocarcinoma-unclassifiable	COSMIC cancer mutations	mixed_intestinal_and_diffuse_adenocarcinoma-unclassifiable	951	7	16828	49	MACF1,FMN2,ATP13A4,ITPR2,GPC5,PARD3,SLC1A2
1.944e-02	-3.94	regulation of glucose transmembrane transport	biological process	GO:0010827	78	2	18204	50	SLC1A2,SORBS1
1.947e-02	-3.94	HAD superfamily/HAD-like	gene3d domains	3.40.50.1000	74	2	14470	42	ATP1A2,ATP13A4
1.954e-02	-3.94	transmembrane receptor protein kinase activity	molecular function	GO:0019199	81	2	18094	48	BMPR1B,NTRK2
1.961e-02	-3.93	Excitatory Neural Signalling Through 5-HTR 4 and Serotonin	SMPDB pathways	SMP0000309	9	1	1369	3	ADCY2
1.961e-02	-3.93	Intracellular Signalling Through Histamine H2 Receptor and Histamine	SMPDB pathways	SMP0000335	9	1	1369	3	ADCY2
1.961e-02	-3.93	Excitatory Neural Signalling Through 5-HTR 7 and Serotonin	SMPDB pathways	SMP0000311	9	1	1369	3	ADCY2
1.961e-02	-3.93	Excitatory Neural Signalling Through 5-HTR 6 and Serotonin	SMPDB pathways	SMP0000312	9	1	1369	3	ADCY2
1.961e-02	-3.93	Intracellular Signalling Through FSH Receptor and Follicle Stimulating Hormone	SMPDB pathways	SMP0000333	9	1	1369	3	ADCY2
1.977e-02	-3.92	NGF signalling via TRKA from the plasma membrane	REACTOME pathways	R-HSA-187037	387	4	10285	28	ITPR2,NTRK2,NRG3,ADCY2
1.985e-02	-3.92	MAPRE3 (microtubule associated protein RP/EB family member 3)	protein interactions	22924	224	3	19454	50	ABLIM1,GPM6A,MACF1
1.991e-02	-3.92	polysaccharide metabolic process	biological process	GO:0005976	79	2	18204	50	FUT9,CSGALNACT1
1.991e-02	-3.92	FGFR1 (fibroblast growth factor receptor 1)	protein interactions	2260	611	5	19454	50	ABLIM1,TNIK,NHSL1,DTNA,PARD3
2.002e-02	-3.91	GLYPICAN	prosite domains	PS01207	6	1	12186	41	GPC5
2.002e-02	-3.91	GAR	prosite domains	PS51460	6	1	12186	41	MACF1
2.008e-02	-3.91	KLF3 (KLF transcription factor 3)	protein interactions	51274	225	3	19454	50	TRPS1,SOX5,NFIA
2.018e-02	-3.90	CFAP298 (cilia and flagella associated protein 298)	protein interactions	56683	85	2	19454	50	TRPS1,FMN2
2.020e-02	-3.90	SOX2 (SRY-box transcription factor 2)	protein interactions	6657	1342	8	19454	50	GLIS3,LSAMP,NFIA,ITPR2,TRPS1,MACF1,MSI2,SOX5
2.032e-02	-3.90	Myometrial Relaxation and Contraction Pathways	WikiPathways	WP289	158	3	5310	20	ITPR2,RYR3,ADCY2
2.034e-02	-3.90	zonula adherens	cellular component	GO:0005915	8	1	19108	49	SORBS1
2.034e-02	-3.90	HFE-transferrin receptor complex	cellular component	GO:1990712	8	1	19108	49	BMPR1B
2.038e-02	-3.89	Rasd2 (RASD family, member 2)	protein interactions	75141	8	1	19454	50	BMPR1B
2.038e-02	-3.89	BMP15 (bone morphogenetic protein 15)	protein interactions	9210	8	1	19454	50	BMPR1B
2.038e-02	-3.89	INSM1 (INSM transcriptional repressor 1)	protein interactions	3642	8	1	19454	50	SORBS1
2.038e-02	-3.89	CCK (cholecystokinin)	protein interactions	885	8	1	19454	50	CPE
2.038e-02	-3.89	LHB (luteinizing hormone subunit beta)	protein interactions	3972	8	1	19454	50	NTM
2.038e-02	-3.89	Rps27a (ribosomal protein S27A)	protein interactions	78294	8	1	19454	50	BMPR1B
2.042e-02	-3.89	eye development	biological process	GO:0001654	381	4	18204	50	GPM6A,NFIA,NTRK2,BMPR1B
2.043e-02	-3.89	acral_lentiginous	COSMIC cancer mutations	acral_lentiginous	745	6	16828	49	NRG3,CSGALNACT1,CDH20,ATP13A4,PARD3,MACF1
2.044e-02	-3.89	bone-Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour	COSMIC cancer mutations	bone-Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour	6023	25	16828	49	ZBTB20,PARD3,SLC1A3,SPARCL1,NTRK2,MACF1,MAML2,RYR3,ATP13A4,ATP1A2,NPAS3,RORA,SLC4A4,DTNA,ABLIM1,GLIS3,ITPR2,PTPRZ1,CSGALNACT1,NKAIN3,NRG3,NEBL,ADCY2,SOX5,CTNND2
2.058e-02	-3.88	Transmission across Chemical Synapses	REACTOME pathways	R-HSA-112315	217	3	10285	28	ADCY2,SLC1A3,SLC1A2
2.063e-02	-3.88	FAM171A1 (family with sequence similarity 171 member A1)	protein interactions	221061	86	2	19454	50	NTRK2,PARD3
2.063e-02	-3.88	SYNJ1 (synaptojanin 1)	protein interactions	8867	86	2	19454	50	SORBS1,GPM6A
2.077e-02	-3.87	Glycosaminoglycan biosynthesis, chondroitin sulfate backbone	KEGG pathways	M00058	6	1	7161	25	CSGALNACT1
2.077e-02	-3.87	Glycosaminoglycan biosynthesis, chondroitin sulfate backbone	KEGG pathways	hsa_M00058	6	1	7161	25	CSGALNACT1
2.088e-02	-3.87	NAHCO3TRSPRT	prints domains	PR01232	5	1	5227	22	SLC4A4
2.088e-02	-3.87	PITRANSFER	prints domains	PR00391	5	1	5227	22	PITPNC1
2.101e-02	-3.86	EF_hand_dom	interpro domains	IPR002048	218	3	18521	50	RYR3,SPARCL1,MACF1
2.103e-02	-3.86	alpha-(1->3)-fucosyltransferase activity	molecular function	GO:0046920	8	1	18094	48	FUT9
2.103e-02	-3.86	BMP receptor activity	molecular function	GO:0098821	8	1	18094	48	BMPR1B
2.103e-02	-3.86	sodium ion binding	molecular function	GO:0031402	8	1	18094	48	ATP1A2
2.103e-02	-3.86	P-type potassium transmembrane transporter activity	molecular function	GO:0008556	8	1	18094	48	ATP1A2
2.103e-02	-3.86	glutamate binding	molecular function	GO:0016595	8	1	18094	48	SLC1A3
2.103e-02	-3.86	cellular response to nitrogen compound	biological process	GO:1901699	580	5	18204	50	SORBS1,RYR3,ITPR2,SLC1A2,SLC1A3
2.108e-02	-3.86	ZNF608 (zinc finger protein 608)	protein interactions	57507	87	2	19454	50	SOX5,NFIA
2.108e-02	-3.86	Kctd5 (potassium channel tetramerisation domain containing 5)	protein interactions	69259	87	2	19454	50	SLC1A3,TRPS1
2.108e-02	-3.86	NHLH1 (nescient helix-loop-helix 1)	protein interactions	4807	87	2	19454	50	NFIA,TRPS1
2.113e-02	-3.86	visual system development	biological process	GO:0150063	385	4	18204	50	NFIA,GPM6A,BMPR1B,NTRK2
2.118e-02	-3.85	kidney-carcinoma-papillary_renal_cell_carcinoma	COSMIC cancer mutations	kidney-carcinoma-papillary_renal_cell_carcinoma	6364	26	16828	49	FMN2,RFX4,ATP13A4,RYR3,GPC5,ATP1A2,PITPNC1,NTM,PARD3,ZBTB20,MAML2,MACF1,NTRK2,NRG3,PTPRZ1,ITPR2,CPE,CTNND2,SOX5,ADCY2,ABLIM1,NFIA,BMPR1B,TNIK,SLC4A4,RORA
2.118e-02	-3.85	papillary_renal_cell_carcinoma	COSMIC cancer mutations	papillary_renal_cell_carcinoma	6364	26	16828	49	NFIA,BMPR1B,ABLIM1,SLC4A4,RORA,TNIK,CTNND2,SOX5,CPE,ADCY2,NRG3,ITPR2,PTPRZ1,MAML2,MACF1,NTRK2,ZBTB20,PARD3,NTM,ATP1A2,PITPNC1,GPC5,RFX4,FMN2,ATP13A4,RYR3
2.125e-02	-3.85	acute_lymphoblastic_leukaemia	COSMIC cancer mutations	acute_lymphoblastic_leukaemia	2197	12	16828	49	SOX5,ATP1A2,ADCY2,PTPRZ1,NTRK2,DTNA,BMPR1B,NFIA,TNIK,PARD3B,TRPS1,SLC4A4
2.138e-02	-3.85	AC_N	pfam domains	PF16214	8	1	17795	48	ADCY2
2.138e-02	-3.85	Glyco_tran_10_N	pfam domains	PF17039	8	1	17795	48	FUT9
2.138e-02	-3.85	Glyco_transf_10	pfam domains	PF00852	8	1	17795	48	FUT9
2.138e-02	-3.85	CHGN	pfam domains	PF05679	8	1	17795	48	CSGALNACT1
2.138e-02	-3.85	VHP	pfam domains	PF02209	8	1	17795	48	ABLIM1
2.140e-02	-3.84	Glyco_tran_10_N	interpro domains	IPR031481	8	1	18521	50	FUT9
2.140e-02	-3.84	Glyco_trans_10	interpro domains	IPR001503	8	1	18521	50	FUT9
2.140e-02	-3.84	Villin_headpiece	interpro domains	IPR003128	8	1	18521	50	ABLIM1
2.140e-02	-3.84	GT10-like_C_sf	interpro domains	IPR038577	8	1	18521	50	FUT9
2.140e-02	-3.84	RFX-like	interpro domains	IPR039779	8	1	18521	50	RFX4
2.140e-02	-3.84	Chond_GalNAc	interpro domains	IPR008428	8	1	18521	50	CSGALNACT1
2.140e-02	-3.84	Villin_headpiece_dom_sf	interpro domains	IPR036886	8	1	18521	50	ABLIM1
2.140e-02	-3.84	AC_N	interpro domains	IPR032628	8	1	18521	50	ADCY2
2.140e-02	-3.84	Adcy	interpro domains	IPR030672	8	1	18521	50	ADCY2
2.140e-02	-3.84	Plakin	interpro domains	IPR043197	8	1	18521	50	MACF1
2.142e-02	-3.84	GAS2	smart domains	SM00243	6	1	9717	35	MACF1
2.153e-02	-3.84	RAP2A (RAP2A, member of RAS oncogene family)	protein interactions	5911	88	2	19454	50	BMPR1B,TNIK
2.158e-02	-3.84	Release of Hh-Np from the secreting cell	REACTOME pathways	R-HSA-5362798	8	1	10285	28	GPC5
2.177e-02	-3.83	regulation of L-glutamate import across plasma membrane	biological process	GO:0002036	8	1	18204	50	ATP1A2
2.177e-02	-3.83	gamma-aminobutyric acid metabolic process	biological process	GO:0009448	8	1	18204	50	SLC1A3
2.177e-02	-3.83	dermatan sulfate proteoglycan biosynthetic process	biological process	GO:0050651	8	1	18204	50	CSGALNACT1
2.177e-02	-3.83	cell proliferation in hindbrain	biological process	GO:0021534	8	1	18204	50	RORA
2.177e-02	-3.83	ERBB4 signaling pathway	biological process	GO:0038130	8	1	18204	50	NRG3
2.177e-02	-3.83	meiotic cytokinesis	biological process	GO:0033206	8	1	18204	50	FMN2
2.177e-02	-3.83	heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process	biological process	GO:0015014	8	1	18204	50	CSGALNACT1
2.177e-02	-3.83	cerebellar granule cell precursor proliferation	biological process	GO:0021930	8	1	18204	50	RORA
2.177e-02	-3.83	cell proliferation in external granule layer	biological process	GO:0021924	8	1	18204	50	RORA
2.177e-02	-3.83	regulation of synapse structural plasticity	biological process	GO:0051823	8	1	18204	50	CTNNA2
2.177e-02	-3.83	insulin processing	biological process	GO:0030070	8	1	18204	50	CPE
2.177e-02	-3.83	Intracellular Signalling Through LHCGR Receptor and Luteinizing Hormone/Choriogonadotropin	SMPDB pathways	SMP0000338	10	1	1369	3	ADCY2
2.186e-02	-3.82	skin-upper_arm-malignant_melanoma	COSMIC cancer mutations	skin-upper_arm-malignant_melanoma	553	5	16828	49	PARD3B,FMN2,SLC4A4,ITPR2,FUT9
2.190e-02	-3.82	Axon guidance	KEGG pathways	ko04360	174	3	7161	25	BMPR1B,ABLIM1,PARD3
2.190e-02	-3.82	Axon guidance	KEGG pathways	hsa04360	174	3	7161	25	PARD3,ABLIM1,BMPR1B
2.199e-02	-3.82	SERPINB13 (serpin family B member 13)	protein interactions	5275	89	2	19454	50	PPP2R2B,CSGALNACT1
2.199e-02	-3.82	SOX10 (SRY-box transcription factor 10)	protein interactions	6663	89	2	19454	50	NFIA,TRPS1
2.201e-02	-3.82	-	gene3d domains	2.80.10.50	79	2	14470	42	RYR3,ITPR2
2.203e-02	-3.82	SH3_domain	interpro domains	IPR001452	222	3	18521	50	MACF1,SORBS1,NEBL
2.220e-02	-3.81	Opioid Signalling	REACTOME pathways	R-HSA-111885	85	2	10285	28	ADCY2,ITPR2
2.221e-02	-3.81	sensory system development	biological process	GO:0048880	391	4	18204	50	BMPR1B,NTRK2,NFIA,GPM6A
2.224e-02	-3.81	HMG20A (high mobility group 20A)	protein interactions	10363	234	3	19454	50	NFIA,SOX5,DTNA
2.231e-02	-3.80	carbohydrate derivative biosynthetic process	biological process	GO:1901137	589	5	18204	50	BMPR1B,CSGALNACT1,ADCY2,MGAT4C,FUT9
2.233e-02	-3.80	L-amino acid transport	biological process	GO:0015807	84	2	18204	50	SLC1A2,SLC1A3
2.233e-02	-3.80	proteoglycan metabolic process	biological process	GO:0006029	84	2	18204	50	BMPR1B,CSGALNACT1
2.233e-02	-3.80	peripheral nervous system development	biological process	GO:0007422	84	2	18204	50	PARD3,NTRK2
2.233e-02	-3.80	regulation of sodium ion transport	biological process	GO:0002028	84	2	18204	50	ATP1A2,NKAIN3
2.246e-02	-3.80	CTDSPL (CTD small phosphatase like)	protein interactions	10217	90	2	19454	50	DTNA,FMN2
2.283e-02	-3.78	oligodendrocyte differentiation	biological process	GO:0048709	85	2	18204	50	PTPRZ1,NTRK2
2.283e-02	-3.78	chondrocyte differentiation	biological process	GO:0002062	85	2	18204	50	BMPR1B,SOX5
2.285e-02	-3.78	astrocyte end-foot	cellular component	GO:0097450	9	1	19108	49	AQP4
2.285e-02	-3.78	flotillin complex	cellular component	GO:0016600	9	1	19108	49	SORBS1
2.285e-02	-3.78	platelet dense tubular network membrane	cellular component	GO:0031095	9	1	19108	49	ITPR2
2.290e-02	-3.78	VEPH1 (ventricular zone expressed PH domain containing 1)	protein interactions	79674	9	1	19454	50	BMPR1B
2.290e-02	-3.78	PI3 (peptidase inhibitor 3)	protein interactions	5266	9	1	19454	50	PPP2R2B
2.290e-02	-3.78	IER5 (immediate early response 5)	protein interactions	51278	9	1	19454	50	PPP2R2B
2.290e-02	-3.78	NRXN2 (neurexin 2)	protein interactions	9379	9	1	19454	50	MACF1
2.290e-02	-3.78	Tyw3 (tRNA-yW synthesizing protein 3 homolog (S. cerevisiae))	protein interactions	209584	9	1	19454	50	CTNNA2
2.292e-02	-3.78	FOXI1 (forkhead box I1)	protein interactions	2299	91	2	19454	50	NFIA,TRPS1
2.292e-02	-3.78	SOS1 (SOS Ras/Rac guanine nucleotide exchange factor 1)	protein interactions	6654	91	2	19454	50	SORBS1,TNIK
2.292e-02	-3.78	DGUOK (deoxyguanosine kinase)	protein interactions	1716	91	2	19454	50	GPM6A,NTM
2.299e-02	-3.77	CAMK2A (calcium/calmodulin dependent protein kinase II alpha)	protein interactions	815	237	3	19454	50	SOX5,ITPR2,GPM6A
2.299e-02	-3.77	Glycosyl transferase family 10, C-terminal domain	gene3d domains	3.40.50.11660	8	1	14470	42	FUT9
2.299e-02	-3.77	Villin headpiece domain	gene3d domains	1.10.950.10	8	1	14470	42	ABLIM1
2.318e-02	-3.76	skin-leg-malignant_melanoma-superficial_spreading	COSMIC cancer mutations	skin-leg-malignant_melanoma-superficial_spreading	210	3	16828	49	SLC4A4,ATP13A4,NTM
2.332e-02	-3.76	GS	prosite domains	PS51256	7	1	12186	41	BMPR1B
2.339e-02	-3.76	SOX9 (SRY-box transcription factor 9)	protein interactions	6662	92	2	19454	50	TRPS1,NFIA
2.346e-02	-3.75	response to oxygen-containing compound	biological process	GO:1901700	1546	9	18204	50	ATP1A2,SLC1A2,SORBS1,SLC1A3,ZBTB20,ADCY2,ITPR2,RYR3,RORA
2.371e-02	-3.74	LIM_DOMAIN_1	prosite domains	PS00478	71	2	12186	41	NEBL,ABLIM1
2.371e-02	-3.74	LIM_DOMAIN_2	prosite domains	PS50023	71	2	12186	41	NEBL,ABLIM1
2.387e-02	-3.74	LGALS7B (galectin 7B)	protein interactions	653499	93	2	19454	50	PPP2R2B,CSGALNACT1
2.387e-02	-3.74	ARHGEF6 (Rac/Cdc42 guanine nucleotide exchange factor 6)	protein interactions	9459	93	2	19454	50	ABLIM1,BMPR1B
2.393e-02	-3.73	NAD+ Signalling and Aging	SMPDB pathways	SMP0084271	11	1	1369	3	RORA
2.401e-02	-3.73	ERBIN (erbb2 interacting protein)	protein interactions	55914	241	3	19454	50	CTNND2,NTRK2,PARD3
2.402e-02	-3.73	Band_3_cyto	pfam domains	PF07565	9	1	17795	48	SLC4A4
2.402e-02	-3.73	Activin_recp	pfam domains	PF01064	9	1	17795	48	BMPR1B
2.402e-02	-3.73	RFX_DNA_binding	pfam domains	PF02257	9	1	17795	48	RFX4
2.404e-02	-3.73	Band3_cytoplasmic_dom	interpro domains	IPR013769	9	1	18521	50	SLC4A4
2.404e-02	-3.73	DNA-bd_RFX	interpro domains	IPR003150	9	1	18521	50	RFX4
2.404e-02	-3.73	Activin_recp	interpro domains	IPR000472	9	1	18521	50	BMPR1B
2.404e-02	-3.73	Fol_N	interpro domains	IPR003645	9	1	18521	50	SPARCL1
2.408e-02	-3.73	ion binding	molecular function	GO:0043167	6007	23	18094	48	BMPR1B,DTNA,MGAT4C,CPE,SPARCL1,SLC1A3,ATP1A2,RORA,ZBTB20,ITPR2,TNIK,NTRK2,PITPNC1,CSGALNACT1,ATP13A4,ADCY2,GLIS3,RYR3,SLC1A2,TRPS1,ABLIM1,PARD3,MACF1
2.428e-02	-3.72	Calcium signaling pathway	KEGG pathways	ko04020	181	3	7161	25	ITPR2,RYR3,ADCY2
2.428e-02	-3.72	Calcium signaling pathway	KEGG pathways	hsa04020	181	3	7161	25	ITPR2,RYR3,ADCY2
2.435e-02	-3.72	FOXP4 (forkhead box P4)	protein interactions	116113	94	2	19454	50	SOX5,NFIA
2.435e-02	-3.72	WWC1 (WW and C2 domain containing 1)	protein interactions	23286	94	2	19454	50	TNIK,ABLIM1
2.435e-02	-3.72	QSER1 (glutamine and serine rich 1)	protein interactions	79832	94	2	19454	50	NFIA,SOX5
2.438e-02	-3.71	postsynapse	cellular component	GO:0098794	646	5	19108	49	CTNND2,GPM6A,TNIK,NTRK2,ATP1A2
2.446e-02	-3.71	L-fucose metabolic process	biological process	GO:0042354	9	1	18204	50	FUT9
2.446e-02	-3.71	fucose catabolic process	biological process	GO:0019317	9	1	18204	50	FUT9
2.446e-02	-3.71	polyamine transmembrane transport	biological process	GO:1902047	9	1	18204	50	ATP13A4
2.446e-02	-3.71	negative regulation of striated muscle contraction	biological process	GO:0045988	9	1	18204	50	ATP1A2
2.446e-02	-3.71	negative regulation of actin nucleation	biological process	GO:0051126	9	1	18204	50	CTNNA2
2.446e-02	-3.71	hindbrain radial glia guided cell migration	biological process	GO:0021932	9	1	18204	50	CTNNA2
2.446e-02	-3.71	L-fucose catabolic process	biological process	GO:0042355	9	1	18204	50	FUT9
2.446e-02	-3.71	release of sequestered calcium ion into cytosol by sarcoplasmic reticulum	biological process	GO:0014808	9	1	18204	50	RYR3
2.454e-02	-3.71	acinar_carcinoma	COSMIC cancer mutations	acinar_carcinoma	1978	11	16828	49	BMPR1B,PARD3B,ZBTB20,FUT9,CSGALNACT1,PTPRZ1,FMN2,NHSL1,CTNND2,ATP1A2,SOX5
2.454e-02	-3.71	pancreas-carcinoma-acinar_carcinoma	COSMIC cancer mutations	pancreas-carcinoma-acinar_carcinoma	1978	11	16828	49	BMPR1B,PARD3B,ZBTB20,NHSL1,SOX5,CTNND2,ATP1A2,FUT9,CSGALNACT1,FMN2,PTPRZ1
2.459e-02	-3.71	human chr5p15.1	chromosome location	human chr5p15.1	13	1	26134	50	FBXL7
2.468e-02	-3.70	lung-carcinoma-bronchioloalveolar_adenocarcinoma	COSMIC cancer mutations	lung-carcinoma-bronchioloalveolar_adenocarcinoma	778	6	16828	49	TNIK,BMPR1B,ADCY2,NTRK2,SOX5,CTNND2
2.468e-02	-3.70	bronchioloalveolar_adenocarcinoma	COSMIC cancer mutations	bronchioloalveolar_adenocarcinoma	778	6	16828	49	TNIK,NTRK2,ADCY2,BMPR1B,SOX5,CTNND2
2.468e-02	-3.70	skeletal system morphogenesis	biological process	GO:0048705	228	3	18204	50	BMPR1B,CSGALNACT1,SOX5
2.487e-02	-3.69	positive regulation of lipid biosynthetic process	biological process	GO:0046889	89	2	18204	50	ZBTB20,SORBS1
2.495e-02	-3.69	GS	smart domains	SM00467	7	1	9717	35	BMPR1B
2.495e-02	-3.69	PLEC	smart domains	SM00250	7	1	9717	35	MACF1
2.496e-02	-3.69	DNA-binding transcription factor activity, RNA polymerase II-specific	molecular function	GO:0000981	1355	8	18094	48	NPAS3,TRPS1,SOX5,GLIS3,RFX4,RORA,ZBTB20,NFIA
2.500e-02	-3.69	ACTIVIN2R	prints domains	PR00653	6	1	5227	22	BMPR1B
2.521e-02	-3.68	sarcoplasm	cellular component	GO:0016528	96	2	19108	49	ITPR2,RYR3
2.523e-02	-3.68	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-NK-T_cell_lymphoma	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-NK-T_cell_lymphoma	217	3	16828	49	RFX4,MGAT4C,DTNA
2.536e-02	-3.67	perineuronal net	cellular component	GO:0072534	10	1	19108	49	PTPRZ1
2.539e-02	-3.67	regulation of purine nucleotide metabolic process	biological process	GO:1900542	90	2	18204	50	SLC4A4,ZBTB20
2.541e-02	-3.67	SLC8A2 (solute carrier family 8 member A2)	protein interactions	6543	10	1	19454	50	GPM6A
2.541e-02	-3.67	GSG1 (germ cell associated 1)	protein interactions	83445	10	1	19454	50	PITPNC1
2.541e-02	-3.67	DEFA1B (defensin alpha 1B)	protein interactions	728358	10	1	19454	50	PPP2R2B
2.541e-02	-3.67	Smurf2 (SMAD specific E3 ubiquitin protein ligase 2)	protein interactions	66313	10	1	19454	50	GLIS3
2.541e-02	-3.67	SERPINB11 (serpin family B member 11)	protein interactions	89778	10	1	19454	50	CPE
2.541e-02	-3.67	P2rx7 (purinergic receptor P2X 7)	protein interactions	29665	10	1	19454	50	PTPRZ1
2.541e-02	-3.67	BANK1 (B cell scaffold protein with ankyrin repeats 1)	protein interactions	55024	10	1	19454	50	ITPR2
2.541e-02	-3.67	CALB2 (calbindin 2)	protein interactions	794	10	1	19454	50	GPM6A
2.541e-02	-3.67	Vbp1 (von Hippel-Lindau binding protein 1)	protein interactions	22327	10	1	19454	50	ABLIM1
2.547e-02	-3.67	YWHAZ (tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein zeta)	protein interactions	7534	1138	7	19454	50	NHSL1,MACF1,PARD3B,PARD3,ABLIM1,SORBS1,PITPNC1
2.551e-02	-3.67	lipid binding	molecular function	GO:0008289	861	6	18094	48	ATP1A2,ITPR2,RORA,PARD3B,PITPNC1,PARD3
2.566e-02	-3.66	adrenal_cortical_carcinoma	COSMIC cancer mutations	adrenal_cortical_carcinoma	2256	12	16828	49	CTNND2,ATP1A2,SOX5,NHSL1,NRG3,PTPRZ1,RFX4,FMN2,MAML2,NTRK2,SLC1A2,ZBTB20
2.573e-02	-3.66	Post-translational modification: synthesis of GPI-anchored proteins	REACTOME pathways	R-HSA-163125	92	2	10285	28	LSAMP,NTM
2.585e-02	-3.66	NCOR2 (nuclear receptor corepressor 2)	protein interactions	9612	248	3	19454	50	TNIK,SOX5,NFIA
2.592e-02	-3.65	response to BMP	biological process	GO:0071772	91	2	18204	50	BMPR1B,NFIA
2.592e-02	-3.65	cellular response to BMP stimulus	biological process	GO:0071773	91	2	18204	50	NFIA,BMPR1B
2.592e-02	-3.65	regulation of nucleotide metabolic process	biological process	GO:0006140	91	2	18204	50	ZBTB20,SLC4A4
2.609e-02	-3.65	Lactose Intolerance	SMPDB pathways	SMP0000458	12	1	1369	3	ATP1A2
2.609e-02	-3.65	Lactose Degradation	SMPDB pathways	SMP0000457	12	1	1369	3	ATP1A2
2.621e-02	-3.64	oesophagus-carcinoma-adenocarcinoma	COSMIC cancer mutations	oesophagus-carcinoma-adenocarcinoma	13112	44	16828	49	SLC4A4,RORA,CDH20,TNIK,MGAT4C,NKAIN3,FUT9,NRG3,ITPR2,PTPRZ1,FBXL7,CTNND2,SOX5,CPE,ADCY2,NEBL,TRPS1,PARD3,SORBS1,NTRK2,FMN2,RYR3,ATP13A4,ATP1A2,SLC1A2,BMPR1B,PARD3B,GLIS3,CSGALNACT1,LSAMP,SFXN5,SLC1A3,ZBTB20,NTM,MAML2,SPARCL1,MACF1,GPM6A,PPP2R2B,GPC5,RFX4,NHSL1,NPAS3,AQP4
2.622e-02	-3.64	neurotrophin binding	molecular function	GO:0043121	10	1	18094	48	NTRK2
2.622e-02	-3.64	phosphatidylinositol transfer activity	molecular function	GO:0008526	10	1	18094	48	PITPNC1
2.622e-02	-3.64	polyamine transmembrane transporter activity	molecular function	GO:0015203	10	1	18094	48	ATP13A4
2.625e-02	-3.64	cell surface	cellular component	GO:0009986	896	6	19108	49	SLC1A3,SLC1A2,SLC4A4,GPC5,AQP4,ATP1A2
2.631e-02	-3.64	DNAAF2 (dynein axonemal assembly factor 2)	protein interactions	55172	98	2	19454	50	LSAMP,GPM6A
2.640e-02	-3.63	terminal O-glycans residues modification	BIOCYC pathways	HUMAN_PWY-7434	8	1	902	3	FUT9
2.640e-02	-3.63	mannosyl-glycoprotein N-acetylglucosaminyltransferases	BIOCYC pathways	META_PWY-7426	8	1	902	3	MGAT4C
2.645e-02	-3.63	establishment of localization	biological process	GO:0051234	3887	17	18204	50	ATP1A2,NTRK2,FMN2,PARD3B,MACF1,ATP13A4,CPE,PITPNC1,SLC1A2,GPM6A,PARD3,AQP4,SFXN5,SLC1A3,ITPR2,RYR3,SLC4A4
2.645e-02	-3.63	protein tetramerization	biological process	GO:0051262	92	2	18204	50	AQP4,RYR3
2.646e-02	-3.63	human chr6q16.1	chromosome location	human chr6q16.1	14	1	26134	50	FUT9
2.646e-02	-3.63	human chr2p13.2	chromosome location	human chr2p13.2	14	1	26134	50	SFXN5
2.654e-02	-3.63	upper_arm	COSMIC cancer mutations	upper_arm	582	5	16828	49	SLC4A4,ITPR2,FMN2,PARD3B,FUT9
2.661e-02	-3.63	HP	prosite domains	PS51089	8	1	12186	41	ABLIM1
2.661e-02	-3.63	GATA_ZN_FINGER_1	prosite domains	PS00344	8	1	12186	41	TRPS1
2.666e-02	-3.62	HCO3_cotransp	pfam domains	PF00955	10	1	17795	48	SLC4A4
2.666e-02	-3.62	PAS_3	pfam domains	PF08447	10	1	17795	48	NPAS3
2.666e-02	-3.62	Ig_sub2	interpro domains	IPR003598	239	3	18521	50	NTRK2,LSAMP,NTM
2.668e-02	-3.62	PTrfase/Anion_transptr	interpro domains	IPR016152	10	1	18521	50	SLC4A4
2.668e-02	-3.62	HCO3_transpt-like_TM_dom	interpro domains	IPR011531	10	1	18521	50	SLC4A4
2.668e-02	-3.62	HCO3_transpt_euk	interpro domains	IPR003020	10	1	18521	50	SLC4A4
2.668e-02	-3.62	PAS_fold_3	interpro domains	IPR013655	10	1	18521	50	NPAS3
2.668e-02	-3.62	MIP_CS	interpro domains	IPR022357	10	1	18521	50	AQP4
2.668e-02	-3.62	SH3 Domains	gene3d domains	2.30.30.40	223	3	14470	42	NEBL,SORBS1,MACF1
2.680e-02	-3.62	ZFHX3 (zinc finger homeobox 3)	protein interactions	463	99	2	19454	50	SOX5,TRPS1
2.682e-02	-3.62	LIM	smart domains	SM00132	71	2	9717	35	ABLIM1,NEBL
2.683e-02	-3.62	ATPase-coupled transmembrane transporter activity	molecular function	GO:0042626	96	2	18094	48	ATP1A2,ATP13A4
2.690e-02	-3.62	Bicarbonate transporters	REACTOME pathways	R-HSA-425381	10	1	10285	28	SLC4A4
2.690e-02	-3.62	Adenylate cyclase activating pathway	REACTOME pathways	R-HSA-170660	10	1	10285	28	ADCY2
2.690e-02	-3.62	PI3K events in ERBB4 signaling	REACTOME pathways	R-HSA-1250342	10	1	10285	28	NRG3
2.691e-02	-3.62	PROKAR_LIPOPROTEIN	prosite domains	PS51257	76	2	12186	41	CPE,GLIS3
2.693e-02	-3.61	behavior	biological process	GO:0007610	619	5	18204	50	NTRK2,ATP1A2,SLC1A3,SLC1A2,PTPRZ1
2.693e-02	-3.61	CRX (cone-rod homeobox)	protein interactions	1406	252	3	19454	50	NFIA,TRPS1,SOX5
2.695e-02	-3.61	non_small_cell_carcinoma	COSMIC cancer mutations	non_small_cell_carcinoma	5198	22	16828	49	ATP13A4,PPP2R2B,PITPNC1,NPAS3,TRPS1,PARD3,MSI2,SLC1A3,SPARCL1,NTRK2,MAML2,ITPR2,PTPRZ1,FBXL7,LSAMP,ADCY2,CTNND2,SOX5,RORA,TNIK,BMPR1B,ABLIM1
2.695e-02	-3.61	lung-carcinoma-non_small_cell_carcinoma	COSMIC cancer mutations	lung-carcinoma-non_small_cell_carcinoma	5198	22	16828	49	MAML2,SPARCL1,NTRK2,SLC1A3,TRPS1,PARD3,MSI2,NPAS3,PITPNC1,PPP2R2B,ATP13A4,BMPR1B,ABLIM1,RORA,TNIK,CTNND2,SOX5,ADCY2,LSAMP,ITPR2,PTPRZ1,FBXL7
2.714e-02	-3.61	cAMP biosynthetic process	biological process	GO:0006171	10	1	18204	50	ADCY2
2.714e-02	-3.61	release of sequestered calcium ion into cytosol by endoplasmic reticulum	biological process	GO:1903514	10	1	18204	50	RYR3
2.714e-02	-3.61	somatic stem cell division	biological process	GO:0048103	10	1	18204	50	FUT9
2.714e-02	-3.61	trans-synaptic signaling, modulating synaptic transmission	biological process	GO:0099550	10	1	18204	50	NTRK2
2.714e-02	-3.61	regulation of mesenchymal stem cell differentiation	biological process	GO:2000739	10	1	18204	50	SOX5
2.714e-02	-3.61	retinal rod cell development	biological process	GO:0046548	10	1	18204	50	NTRK2
2.714e-02	-3.61	substrate-independent telencephalic tangential interneuron migration	biological process	GO:0021843	10	1	18204	50	NRG3
2.714e-02	-3.61	cellular response to brain-derived neurotrophic factor stimulus	biological process	GO:1990416	10	1	18204	50	NTRK2
2.714e-02	-3.61	substrate-independent telencephalic tangential migration	biological process	GO:0021826	10	1	18204	50	NRG3
2.731e-02	-3.60	ATP4A (ATPase H+/K+ transporting subunit alpha)	protein interactions	495	100	2	19454	50	ATP1A2,GPM6A
2.738e-02	-3.60	cellular response to chemical stimulus	biological process	GO:0070887	2411	12	18204	50	ZBTB20,ADCY2,FMN2,NTRK2,ATP1A2,RORA,RYR3,SLC1A3,ITPR2,SORBS1,AQP4,SLC1A2
2.756e-02	-3.59	muscle contraction	biological process	GO:0006936	238	3	18204	50	ATP1A2,RYR3,DTNA
2.769e-02	-3.59	NK-T_cell_lymphoma	COSMIC cancer mutations	NK-T_cell_lymphoma	225	3	16828	49	MGAT4C,DTNA,RFX4
2.776e-02	-3.58	DYNLL2 (dynein light chain LC8-type 2)	protein interactions	140735	255	3	19454	50	NFIA,TRPS1,NHSL1
2.781e-02	-3.58	EVPL (envoplakin)	protein interactions	2125	101	2	19454	50	PPP2R2B,NKAIN3
2.786e-02	-3.58	platelet dense tubular network	cellular component	GO:0031094	11	1	19108	49	ITPR2
2.786e-02	-3.58	perisynaptic extracellular matrix	cellular component	GO:0098966	11	1	19108	49	PTPRZ1
2.792e-02	-3.58	cellular component organization or biogenesis	biological process	GO:0071840	5850	23	18204	50	ABLIM1,RFX4,NFIA,PTPRZ1,NEBL,NRG3,FMN2,CTNNA2,SPARCL1,SLC1A2,BMPR1B,PITPNC1,AQP4,GPM6A,CTNND2,PARD3B,MACF1,RYR3,TNIK,CSGALNACT1,SORBS1,CDH20,PARD3
2.792e-02	-3.58	Cobll1 (Cobl-like 1)	protein interactions	319876	11	1	19454	50	ABLIM1
2.792e-02	-3.58	SYN3 (synapsin III)	protein interactions	8224	11	1	19454	50	GPM6A
2.792e-02	-3.58	ADCY5 (adenylate cyclase 5)	protein interactions	111	11	1	19454	50	ADCY2
2.792e-02	-3.58	IRAG1 (inositol 1,4,5-triphosphate receptor associated 1)	protein interactions	10335	11	1	19454	50	ITPR2
2.792e-02	-3.58	Gtf2e2 (general transcription factor II E, polypeptide 2 (beta subunit))	protein interactions	68153	11	1	19454	50	NHSL1
2.792e-02	-3.58	Batf3 (basic leucine zipper transcription factor, ATF-like 3)	protein interactions	381319	11	1	19454	50	MACF1
2.792e-02	-3.58	NTS (neurotensin)	protein interactions	4922	11	1	19454	50	CPE
2.792e-02	-3.58	Wipi2 (WD repeat domain, phosphoinositide interacting 2)	protein interactions	74781	11	1	19454	50	MACF1
2.792e-02	-3.58	AQP5 (aquaporin 5)	protein interactions	362	11	1	19454	50	ATP1A2
2.795e-02	-3.58	axon development	biological process	GO:0061564	420	4	18204	50	CTNNA2,PARD3,PTPRZ1,BMPR1B
2.802e-02	-3.58	RNA polymerase II transcription regulatory region sequence-specific DNA binding	molecular function	GO:0000977	1385	8	18094	48	NPAS3,TRPS1,SOX5,GLIS3,RFX4,RORA,ZBTB20,NFIA
2.807e-02	-3.57	calcium ion transmembrane import into cytosol	biological process	GO:0097553	95	2	18204	50	ITPR2,RYR3
2.809e-02	-3.57	enzyme-linked receptor protein signaling pathway	biological process	GO:0007167	626	5	18204	50	NTRK2,BMPR1B,NRG3,NFIA,SORBS1
2.824e-02	-3.57	Trehalose Degradation	SMPDB pathways	SMP0000467	13	1	1369	3	ATP1A2
2.832e-02	-3.56	human chr8q12.3	chromosome location	human chr8q12.3	15	1	26134	50	NKAIN3
2.832e-02	-3.56	human chr10p12.31	chromosome location	human chr10p12.31	15	1	26134	50	NEBL
2.846e-02	-3.56	VHP	smart domains	SM00153	8	1	9717	35	ABLIM1
2.865e-02	-3.55	urinary_tract-bladder-carcinoma	COSMIC cancer mutations	urinary_tract-bladder-carcinoma	14050	46	16828	49	TRPS1,PARD3,SORBS1,NTRK2,FMN2,ATP13A4,RYR3,ATP1A2,PITPNC1,ABLIM1,SLC4A4,RORA,CDH20,TNIK,MGAT4C,FUT9,NRG3,ITPR2,PTPRZ1,FBXL7,CTNND2,SOX5,CPE,ADCY2,NEBL,SLC1A3,ZBTB20,MSI2,NTM,MAML2,SPARCL1,MACF1,GPM6A,PPP2R2B,GPC5,RFX4,NPAS3,NFIA,DTNA,BMPR1B,SLC1A2,PARD3B,GLIS3,CSGALNACT1,LSAMP,SFXN5
2.866e-02	-3.55	Helical hairpin bin	gene3d domains	1.10.287.570	10	1	14470	42	SLC4A4
2.872e-02	-3.55	cellular component biogenesis	biological process	GO:0044085	2716	13	18204	50	NRG3,NEBL,FMN2,RFX4,ABLIM1,SORBS1,AQP4,PARD3,GPM6A,CDH20,SLC1A2,TNIK,RYR3
2.880e-02	-3.55	sulfur amino acid transmembrane transporter activity	molecular function	GO:0000099	11	1	18094	48	SLC1A2
2.884e-02	-3.55	RAB6B (RAB6B, member RAS oncogene family)	protein interactions	51560	103	2	19454	50	BMPR1B,GPM6A
2.884e-02	-3.55	ZDHHC5 (zinc finger DHHC-type palmitoyltransferase 5)	protein interactions	25921	103	2	19454	50	PARD3,NTRK2
2.884e-02	-3.55	CSGALNACT2 (chondroitin sulfate N-acetylgalactosaminyltransferase 2)	protein interactions	55454	103	2	19454	50	MGAT4C,CSGALNACT1
2.893e-02	-3.54	amino acid transmembrane transporter activity	molecular function	GO:0015171	100	2	18094	48	SLC1A2,SLC1A3
2.917e-02	-3.53	amino acid transmembrane transport	biological process	GO:0003333	97	2	18204	50	SLC1A3,SLC1A2
2.931e-02	-3.53	Tyr_kinase_rcpt_2_CS	interpro domains	IPR002011	11	1	18521	50	NTRK2
2.980e-02	-3.51	organic substance transport	biological process	GO:0071702	1881	10	18204	50	ATP13A4,SLC1A3,CPE,SLC4A4,SLC1A2,NTRK2,PITPNC1,FMN2,MACF1,SFXN5
2.981e-02	-3.51	ectodermal placode morphogenesis	biological process	GO:0071697	11	1	18204	50	NRG3
2.981e-02	-3.51	glutamate secretion	biological process	GO:0014047	11	1	18204	50	NTRK2
2.981e-02	-3.51	establishment or maintenance of transmembrane electrochemical gradient	biological process	GO:0010248	11	1	18204	50	ATP1A2
2.981e-02	-3.51	lactone metabolic process	biological process	GO:1901334	11	1	18204	50	ATP1A2
2.981e-02	-3.51	heparin biosynthetic process	biological process	GO:0030210	11	1	18204	50	CSGALNACT1
2.981e-02	-3.51	ectodermal placode formation	biological process	GO:0060788	11	1	18204	50	NRG3
2.981e-02	-3.51	cellular response to caffeine	biological process	GO:0071313	11	1	18204	50	RYR3
2.981e-02	-3.51	L-ascorbic acid metabolic process	biological process	GO:0019852	11	1	18204	50	ATP1A2
2.981e-02	-3.51	polyamine transport	biological process	GO:0015846	11	1	18204	50	ATP13A4
2.981e-02	-3.51	antral ovarian follicle growth	biological process	GO:0001547	11	1	18204	50	BMPR1B
2.981e-02	-3.51	negative regulation of neuron migration	biological process	GO:2001223	11	1	18204	50	NRG3
2.981e-02	-3.51	PPP2CA (protein phosphatase 2 catalytic subunit alpha)	protein interactions	5515	458	4	19454	50	NHSL1,PPP2R2B,BMPR1B,CSGALNACT1
2.984e-02	-3.51	cell motility	biological process	GO:0048870	1101	7	18204	50	NRG3,GPC5,FMN2,NTRK2,CTNNA2,CDH20,GPM6A
2.988e-02	-3.51	BEND3 (BEN domain containing 3)	protein interactions	57673	105	2	19454	50	TRPS1,TNIK
2.989e-02	-3.51	RFX_DBD	prosite domains	PS51526	9	1	12186	41	RFX4
2.999e-02	-3.51	positive regulation of neurogenesis	biological process	GO:0050769	246	3	18204	50	MACF1,NTRK2,PTPRZ1
2.999e-02	-3.51	regulation of synapse organization	biological process	GO:0050807	246	3	18204	50	GPM6A,CTNNA2,NTRK2
3.028e-02	-3.50	bone morphogenesis	biological process	GO:0060349	99	2	18204	50	BMPR1B,CSGALNACT1
3.034e-02	-3.50	trans-synaptic signaling	biological process	GO:0099537	431	4	18204	50	DTNA,SLC1A2,SLC1A3,NTRK2
3.034e-02	-3.50	response to wounding	biological process	GO:0009611	431	4	18204	50	SLC1A2,SLC1A3,MACF1,NFIA
3.035e-02	-3.49	sodium:potassium-exchanging ATPase complex	cellular component	GO:0005890	12	1	19108	49	ATP1A2
3.035e-02	-3.49	synapse-associated extracellular matrix	cellular component	GO:0099535	12	1	19108	49	PTPRZ1
3.040e-02	-3.49	USP6NL (USP6 N-terminal like)	protein interactions	9712	106	2	19454	50	PARD3,NTRK2
3.042e-02	-3.49	LMP-1 (latent membrane protein LMP-1)	protein interactions	3783750	12	1	19454	50	TNIK
3.042e-02	-3.49	CA4 (carbonic anhydrase 4)	protein interactions	762	12	1	19454	50	SLC4A4
3.042e-02	-3.49	Pard6b (par-6 family cell polarity regulator beta)	protein interactions	58220	12	1	19454	50	PARD3
3.042e-02	-3.49	NTF4 (neurotrophin 4)	protein interactions	4909	12	1	19454	50	NTRK2
3.042e-02	-3.49	PROK2 (prokineticin 2)	protein interactions	60675	12	1	19454	50	CPE
3.042e-02	-3.49	ART4 (ADP-ribosyltransferase 4 (inactive) (Dombrock blood group))	protein interactions	420	12	1	19454	50	GPM6A
3.042e-02	-3.49	BAMBI (BMP and activin membrane bound inhibitor)	protein interactions	25805	12	1	19454	50	BMPR1B
3.079e-02	-3.48	inorganic ion homeostasis	biological process	GO:0098771	433	4	18204	50	ATP1A2,SLC1A3,ATP13A4,RYR3
3.138e-02	-3.46	adenylate cyclase binding	molecular function	GO:0008179	12	1	18094	48	ADCY2
3.138e-02	-3.46	inositol 1,4,5 trisphosphate binding	molecular function	GO:0070679	12	1	18094	48	ITPR2
3.142e-02	-3.46	regulation of glucose metabolic process	biological process	GO:0010906	101	2	18204	50	RORA,SORBS1
3.147e-02	-3.46	EN1 (engrailed homeobox 1)	protein interactions	2019	108	2	19454	50	NFIA,TRPS1
3.147e-02	-3.46	FKBP1A (FKBP prolyl isomerase 1A)	protein interactions	2280	108	2	19454	50	RYR3,MSI2
3.147e-02	-3.46	PAX8 (paired box 8)	protein interactions	7849	108	2	19454	50	NFIA,TRPS1
3.147e-02	-3.46	DSG4 (desmoglein 4)	protein interactions	147409	108	2	19454	50	SPARCL1,CSGALNACT1
3.148e-02	-3.46	Carboxypeptidase-like, regulatory domain	gene3d domains	2.60.40.1120	11	1	14470	42	CPE
3.149e-02	-3.46	PFN1 (profilin 1)	protein interactions	5216	466	4	19454	50	FMN2,ABLIM1,MACF1,NHSL1
3.151e-02	-3.46	VCL (vinculin)	protein interactions	7414	268	3	19454	50	NEBL,MACF1,SORBS1
3.157e-02	-3.46	calcium ion transport	biological process	GO:0006816	251	3	18204	50	RYR3,GPM6A,ITPR2
3.189e-02	-3.45	regulation of synapse structure or activity	biological process	GO:0050803	252	3	18204	50	CTNNA2,GPM6A,NTRK2
3.190e-02	-3.45	MH1	pfam domains	PF03165	12	1	17795	48	NFIA
3.190e-02	-3.45	CarboxypepD_reg	pfam domains	PF13620	12	1	17795	48	CPE
3.193e-02	-3.44	MAD_homology1_Dwarfin-type	interpro domains	IPR003619	12	1	18521	50	NFIA
3.193e-02	-3.44	TGFB_receptor	interpro domains	IPR000333	12	1	18521	50	BMPR1B
3.197e-02	-3.44	FOLN	smart domains	SM00274	9	1	9717	35	SPARCL1
3.200e-02	-3.44	CLSTN1 (calsyntenin 1)	protein interactions	22883	109	2	19454	50	MGAT4C,SLC1A3
3.204e-02	-3.44	human chr9q21.33	chromosome location	human chr9q21.33	17	1	26134	50	NTRK2
3.207e-02	-3.44	biliary_tract-bile_duct-carcinoma-adenocarcinoma	COSMIC cancer mutations	biliary_tract-bile_duct-carcinoma-adenocarcinoma	15095	48	16828	49	LSAMP,CSGALNACT1,SFXN5,PARD3B,SLC1A2,BMPR1B,DTNA,NFIA,GLIS3,RFX4,GPC5,PPP2R2B,AQP4,NPAS3,NHSL1,MSI2,NTM,ZBTB20,SLC1A3,GPM6A,MACF1,SPARCL1,MAML2,FBXL7,PTPRZ1,ITPR2,NRG3,FUT9,NEBL,ADCY2,CPE,SOX5,CTNND2,TNIK,CDH20,RORA,SLC4A4,ABLIM1,MGAT4C,RYR3,ATP13A4,FMN2,PITPNC1,ATP1A2,PARD3,TRPS1,NTRK2,SORBS1
3.207e-02	-3.44	bile_duct	COSMIC cancer mutations	bile_duct	15095	48	16828	49	MGAT4C,SLC4A4,RORA,CDH20,TNIK,ABLIM1,ADCY2,NEBL,CTNND2,SOX5,CPE,ITPR2,PTPRZ1,FBXL7,FUT9,NRG3,NTRK2,SORBS1,TRPS1,PARD3,PITPNC1,ATP1A2,FMN2,RYR3,ATP13A4,GLIS3,PARD3B,NFIA,DTNA,BMPR1B,SLC1A2,SFXN5,CSGALNACT1,LSAMP,SPARCL1,MACF1,GPM6A,MAML2,ZBTB20,MSI2,NTM,SLC1A3,AQP4,NHSL1,NPAS3,GPC5,RFX4,PPP2R2B
3.220e-02	-3.44	Defective EXT2 causes exostoses 2	REACTOME pathways	R-HSA-3656237	12	1	10285	28	GPC5
3.220e-02	-3.44	Defective EXT1 causes exostoses 1, TRPS2 and CHDS	REACTOME pathways	R-HSA-3656253	12	1	10285	28	GPC5
3.248e-02	-3.43	mammalian oogenesis stage	biological process	GO:0022605	12	1	18204	50	BMPR1B
3.248e-02	-3.43	auditory behavior	biological process	GO:0031223	12	1	18204	50	SLC1A3
3.248e-02	-3.43	positive regulation of extrinsic apoptotic signaling pathway via death domain receptors	biological process	GO:1902043	12	1	18204	50	BMPR1B
3.248e-02	-3.43	sulfur amino acid transport	biological process	GO:0000101	12	1	18204	50	SLC1A2
3.248e-02	-3.43	dermatan sulfate proteoglycan metabolic process	biological process	GO:0050655	12	1	18204	50	CSGALNACT1
3.250e-02	-3.43	DNA-binding transcription repressor activity, RNA polymerase II-specific	molecular function	GO:0001227	263	3	18094	48	ZBTB20,TRPS1,GLIS3
3.254e-02	-3.43	LZTR1 (leucine zipper like post translational regulator 1)	protein interactions	8216	110	2	19454	50	BMPR1B,PARD3B
3.264e-02	-3.42	functioning	COSMIC cancer mutations	functioning	1803	10	16828	49	NTRK2,MAML2,NHSL1,SOX5,FMN2,RFX4,PTPRZ1,ZBTB20,NRG3,SLC1A2
3.264e-02	-3.42	adrenal_gland-adrenal_gland-adrenal_cortical_carcinoma-functioning	COSMIC cancer mutations	adrenal_gland-adrenal_gland-adrenal_cortical_carcinoma-functioning	1803	10	16828	49	NHSL1,MAML2,SOX5,NTRK2,NRG3,SLC1A2,FMN2,RFX4,PTPRZ1,ZBTB20
3.271e-02	-3.42	RDX (radixin)	protein interactions	5962	272	3	19454	50	ABLIM1,MACF1,NEBL
3.276e-02	-3.42	steroid binding	molecular function	GO:0005496	107	2	18094	48	RORA,ATP1A2
3.277e-02	-3.42	Aldosterone synthesis and secretion	KEGG pathways	ko04925	82	2	7161	25	ADCY2,ITPR2
3.277e-02	-3.42	Aldosterone synthesis and secretion	KEGG pathways	hsa04925	82	2	7161	25	ADCY2,ITPR2
3.291e-02	-3.41	TBCC (tubulin folding cofactor C)	protein interactions	6903	13	1	19454	50	NTM
3.291e-02	-3.41	JAM2 (junctional adhesion molecule 2)	protein interactions	58494	13	1	19454	50	PARD3
3.291e-02	-3.41	PCDHA2 (protocadherin alpha 2)	protein interactions	56146	13	1	19454	50	NFIA
3.291e-02	-3.41	SPINK5 (serine peptidase inhibitor Kazal type 5)	protein interactions	11005	13	1	19454	50	CSGALNACT1
3.291e-02	-3.41	RAB3C (RAB3C, member RAS oncogene family)	protein interactions	115827	13	1	19454	50	GPM6A
3.302e-02	-3.41	FLOT2 (flotillin 2)	protein interactions	2319	273	3	19454	50	SOX5,PARD3,NTRK2
3.310e-02	-3.41	bladder	COSMIC cancer mutations	bladder	14112	46	16828	49	NPAS3,PPP2R2B,RFX4,GPC5,MAML2,MACF1,GPM6A,SPARCL1,SLC1A3,NTM,MSI2,ZBTB20,SFXN5,LSAMP,CSGALNACT1,GLIS3,NFIA,DTNA,BMPR1B,SLC1A2,PARD3B,ATP1A2,PITPNC1,FMN2,RYR3,ATP13A4,SORBS1,NTRK2,TRPS1,PARD3,CPE,CTNND2,SOX5,ADCY2,NEBL,NRG3,FUT9,PTPRZ1,FBXL7,ITPR2,MGAT4C,ABLIM1,TNIK,CDH20,SLC4A4,RORA
3.310e-02	-3.41	urinary_tract	COSMIC cancer mutations	urinary_tract	14112	46	16828	49	GLIS3,NFIA,DTNA,BMPR1B,SLC1A2,PARD3B,SFXN5,LSAMP,CSGALNACT1,MAML2,MACF1,GPM6A,SPARCL1,SLC1A3,MSI2,NTM,ZBTB20,NPAS3,PPP2R2B,RFX4,GPC5,MGAT4C,ABLIM1,CDH20,TNIK,SLC4A4,RORA,CPE,CTNND2,SOX5,NEBL,ADCY2,FUT9,NRG3,PTPRZ1,FBXL7,ITPR2,SORBS1,NTRK2,TRPS1,PARD3,ATP1A2,PITPNC1,FMN2,RYR3,ATP13A4
3.315e-02	-3.41	MIP	prosite domains	PS00221	10	1	12186	41	AQP4
3.318e-02	-3.41	protein complex oligomerization	biological process	GO:0051259	256	3	18204	50	RYR3,AQP4,SLC1A2
3.320e-02	-3.41	GATAZNFINGER	prints domains	PR00619	8	1	5227	22	TRPS1
3.363e-02	-3.39	HMGCS1 (3-hydroxy-3-methylglutaryl-CoA synthase 1)	protein interactions	3157	112	2	19454	50	PPP2R2B,GPM6A
3.363e-02	-3.39	CEP170P1 (centrosomal protein 170 pseudogene 1)	protein interactions	645455	112	2	19454	50	MACF1,TRPS1
3.373e-02	-3.39	cellular response to alcohol	biological process	GO:0097306	105	2	18204	50	ITPR2,ADCY2
3.389e-02	-3.38	human chr7q31.32	chromosome location	human chr7q31.32	18	1	26134	50	PTPRZ1
3.389e-02	-3.38	human chr18q21.33	chromosome location	human chr18q21.33	18	1	26134	50	CDH20
3.395e-02	-3.38	fucosyltransferase activity	molecular function	GO:0008417	13	1	18094	48	FUT9
3.395e-02	-3.38	monoatomic cation:bicarbonate symporter activity	molecular function	GO:0140410	13	1	18094	48	SLC4A4
3.395e-02	-3.38	transforming growth factor beta receptor activity	molecular function	GO:0005024	13	1	18094	48	BMPR1B
3.395e-02	-3.38	potassium ion binding	molecular function	GO:0030955	13	1	18094	48	ATP1A2
3.418e-02	-3.38	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-acute_lymphoblastic_leukaemia	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-acute_lymphoblastic_leukaemia	2081	11	16828	49	DTNA,BMPR1B,NFIA,TNIK,PTPRZ1,SLC4A4,TRPS1,SOX5,ATP1A2,NTRK2,ADCY2
3.429e-02	-3.37	Alpha-catenin/vinculin-like	gene3d domains	1.20.120.230	12	1	14470	42	CTNNA2
3.432e-02	-3.37	oogenesis	biological process	GO:0048477	106	2	18204	50	FMN2,BMPR1B
3.438e-02	-3.37	diffuse_adenocarcinoma	COSMIC cancer mutations	diffuse_adenocarcinoma	4383	19	16828	49	ADCY2,NHSL1,SOX5,ATP1A2,CTNND2,RYR3,FMN2,PTPRZ1,RFX4,NRG3,GPM6A,MACF1,MGAT4C,GLIS3,PARD3,TRPS1,ABLIM1,DTNA,SLC1A3
3.438e-02	-3.37	stomach-carcinoma-diffuse_adenocarcinoma	COSMIC cancer mutations	stomach-carcinoma-diffuse_adenocarcinoma	4383	19	16828	49	RYR3,FMN2,PTPRZ1,RFX4,NRG3,ADCY2,NHSL1,SOX5,CTNND2,ATP1A2,PARD3,TRPS1,ABLIM1,SLC1A3,DTNA,GPM6A,MACF1,MGAT4C,GLIS3
3.440e-02	-3.37	DNA-binding transcription factor activity	molecular function	GO:0003700	1441	8	18094	48	NFIA,ZBTB20,SOX5,TRPS1,NPAS3,RORA,RFX4,GLIS3
3.457e-02	-3.36	TJP2 (tight junction protein 2)	protein interactions	9414	278	3	19454	50	NEBL,PARD3,SORBS1
3.459e-02	-3.36	plasma membrane raft	cellular component	GO:0044853	114	2	19108	49	ATP1A2,SORBS1
3.459e-02	-3.36	small molecule binding	molecular function	GO:0036094	6197	23	18094	48	ATP1A2,SLC1A3,SPARCL1,RORA,DTNA,BMPR1B,CPE,MGAT4C,SLC1A2,RYR3,MACF1,ABLIM1,PARD3,TRPS1,TNIK,NTRK2,ITPR2,ZBTB20,GLIS3,ADCY2,ATP13A4,CSGALNACT1,PITPNC1
3.474e-02	-3.36	ORF3b (ORF3b protein)	protein interactions	1489670	114	2	19454	50	ZBTB20,MACF1
3.484e-02	-3.36	NOTCH2 intracellular domain regulates transcription	REACTOME pathways	R-HSA-2197563	13	1	10285	28	MAML2
3.484e-02	-3.36	CLEC7A (Dectin-1) induces NFAT activation	REACTOME pathways	R-HSA-5607763	13	1	10285	28	ITPR2
3.484e-02	-3.36	ERBB2 Activates PTK6 Signaling	REACTOME pathways	R-HSA-8847993	13	1	10285	28	NRG3
3.484e-02	-3.36	Passive transport by Aquaporins	REACTOME pathways	R-HSA-432047	13	1	10285	28	AQP4
3.484e-02	-3.36	Notch-HLH transcription pathway	REACTOME pathways	R-HSA-350054	13	1	10285	28	MAML2
3.493e-02	-3.35	Ion_trans	pfam domains	PF00520	109	2	17795	48	RYR3,ITPR2
3.496e-02	-3.35	response to organic substance	biological process	GO:0010033	2498	12	18204	50	ZBTB20,SLC1A3,ADCY2,ITPR2,RYR3,RORA,ATP1A2,NTRK2,SLC1A2,TNIK,AQP4,SORBS1
3.500e-02	-3.35	Ion_trans_dom	interpro domains	IPR005821	109	2	18521	50	ITPR2,RYR3
3.501e-02	-3.35	Insulin secretion	KEGG pathways	hsa04911	85	2	7161	25	ADCY2,ATP1A2
3.505e-02	-3.35	cellular response to stimulus	biological process	GO:0051716	6307	24	18204	50	RYR3,RORA,ITPR2,PARD3,SORBS1,TNIK,CPE,CTNND2,ADCY2,MAML2,MACF1,ATP1A2,DTNA,SLC1A3,AQP4,PITPNC1,SLC1A2,BMPR1B,NFIA,ZBTB20,SPARCL1,NTRK2,FMN2,NRG3
3.514e-02	-3.35	glial cell fate commitment	biological process	GO:0021781	13	1	18204	50	NFIA
3.514e-02	-3.35	cerebellar Purkinje cell differentiation	biological process	GO:0021702	13	1	18204	50	RORA
3.514e-02	-3.35	prepulse inhibition	biological process	GO:0060134	13	1	18204	50	CTNNA2
3.514e-02	-3.35	T-helper 17 cell differentiation	biological process	GO:0072539	13	1	18204	50	RORA
3.514e-02	-3.35	ectodermal placode development	biological process	GO:0071696	13	1	18204	50	NRG3
3.514e-02	-3.35	negative regulation of cytosolic calcium ion concentration	biological process	GO:0051481	13	1	18204	50	ATP1A2
3.514e-02	-3.35	regulation of respiratory gaseous exchange by nervous system process	biological process	GO:0002087	13	1	18204	50	ATP1A2
3.530e-02	-3.34	TBXT (T-box transcription factor T)	protein interactions	6862	115	2	19454	50	NFIA,TRPS1
3.530e-02	-3.34	DTNA (dystrobrevin alpha)	protein interactions	1837	115	2	19454	50	PARD3,NTRK2
3.530e-02	-3.34	CDH2 (cadherin 2)	protein interactions	1000	115	2	19454	50	PARD3,CTNND2
3.533e-02	-3.34	EF_HAND_2	prosite domains	PS50222	215	3	12186	41	MACF1,RYR3,SPARCL1
3.538e-02	-3.34	DNA-binding transcription repressor activity	molecular function	GO:0001217	272	3	18094	48	TRPS1,ZBTB20,GLIS3
3.540e-02	-3.34	Nedd4 (neural precursor cell expressed, developmentally down-regulated 4)	protein interactions	17999	14	1	19454	50	GLIS3
3.540e-02	-3.34	Asap1 (ArfGAP with SH3 domain, ankyrin repeat and PH domain1)	protein interactions	13196	14	1	19454	50	MACF1
3.540e-02	-3.34	JMJD7-PLA2G4B (JMJD7-PLA2G4B readthrough)	protein interactions	8681	14	1	19454	50	PPP2R2B
3.540e-02	-3.34	FCGBP (Fc gamma binding protein)	protein interactions	8857	14	1	19454	50	PPP2R2B
3.540e-02	-3.34	PLXNA4 (plexin A4)	protein interactions	91584	14	1	19454	50	GPM6A
3.540e-02	-3.34	DACT2 (dishevelled binding antagonist of beta catenin 2)	protein interactions	168002	14	1	19454	50	ZBTB20
3.540e-02	-3.34	MB (myoglobin)	protein interactions	4151	14	1	19454	50	MAML2
3.540e-02	-3.34	BOD1L2 (biorientation of chromosomes in cell division 1 like 2)	protein interactions	284257	14	1	19454	50	FMN2
3.540e-02	-3.34	RHEBL1 (RHEB like 1)	protein interactions	121268	14	1	19454	50	BMPR1B
3.540e-02	-3.34	SPRR2D (small proline rich protein 2D)	protein interactions	6703	14	1	19454	50	PPP2R2B
3.540e-02	-3.34	SLC1A2 (solute carrier family 1 member 2)	protein interactions	6506	14	1	19454	50	SLC1A2
3.559e-02	-3.34	side of membrane	cellular component	GO:0098552	715	5	19108	49	NTM,DTNA,GPC5,AQP4,LSAMP
3.569e-02	-3.33	DYNLL1 (dynein light chain LC8-type 1)	protein interactions	8655	485	4	19454	50	PARD3,NTRK2,PPP2R2B,TRPS1
3.574e-02	-3.33	human chr6q24.1	chromosome location	human chr6q24.1	19	1	26134	50	NHSL1
3.574e-02	-3.33	human chr11q25	chromosome location	human chr11q25	19	1	26134	50	NTM
3.574e-02	-3.33	human chr5p15.2	chromosome location	human chr5p15.2	19	1	26134	50	CTNND2
3.576e-02	-3.33	LAMTOR1 (late endosomal/lysosomal adaptor, MAPK and MTOR activator 1)	protein interactions	55004	714	5	19454	50	SLC1A3,PARD3,DTNA,TNIK,FMN2
3.586e-02	-3.33	SKIL (SKI like proto-oncogene)	protein interactions	6498	116	2	19454	50	MACF1,SPARCL1
3.592e-02	-3.33	PRKACA (protein kinase cAMP-activated catalytic subunit alpha)	protein interactions	5566	486	4	19454	50	SLC4A4,PARD3,ITPR2,TNIK
3.621e-02	-3.32	regulation of nervous system development	biological process	GO:0051960	456	4	18204	50	PARD3,MACF1,NTRK2,PTPRZ1
3.630e-02	-3.32	positive regulation of biological process	biological process	GO:0048518	6326	24	18204	50	SORBS1,PARD3,TNIK,RORA,GPC5,FUT9,MACF1,MAML2,SOX5,ATP1A2,SFXN5,GPM6A,BMPR1B,SLC1A2,NPAS3,GLIS3,SLC4A4,SLC1A3,PTPRZ1,FMN2,NTRK2,NFIA,ZBTB20,RFX4
3.636e-02	-3.31	Integration of energy metabolism	REACTOME pathways	R-HSA-163685	111	2	10285	28	ADCY2,ITPR2
3.641e-02	-3.31	GATA_ZN_FINGER_2	prosite domains	PS50114	11	1	12186	41	TRPS1
3.641e-02	-3.31	RECEPTOR_TYR_KIN_II	prosite domains	PS00239	11	1	12186	41	NTRK2
3.642e-02	-3.31	ELK3 (ETS transcription factor ELK3)	protein interactions	2004	117	2	19454	50	TRPS1,NFIA
3.652e-02	-3.31	microtubule minus-end binding	molecular function	GO:0051011	14	1	18094	48	MACF1
3.670e-02	-3.31	glycosyltransferase activity	molecular function	GO:0016757	276	3	18094	48	MGAT4C,CSGALNACT1,FUT9
3.695e-02	-3.30	synaptic signaling	biological process	GO:0099536	459	4	18204	50	SLC1A2,SLC1A3,NTRK2,DTNA
3.699e-02	-3.30	VSIG8 (V-set and immunoglobulin domain containing 8)	protein interactions	391123	118	2	19454	50	CSGALNACT1,SPARCL1
3.712e-02	-3.29	GATA	pfam domains	PF00320	14	1	17795	48	TRPS1
3.712e-02	-3.29	MIP	pfam domains	PF00230	14	1	17795	48	AQP4
3.715e-02	-3.29	Aquaporin-like	interpro domains	IPR023271	14	1	18521	50	AQP4
3.715e-02	-3.29	MIP	interpro domains	IPR000425	14	1	18521	50	AQP4
3.730e-02	-3.29	Gap junction	KEGG pathways	hsa04540	88	2	7161	25	ADCY2,ITPR2
3.730e-02	-3.29	Gap junction	KEGG pathways	ko04540	88	2	7161	25	ITPR2,ADCY2
3.745e-02	-3.28	DHFR2 (dihydrofolate reductase 2)	protein interactions	200895	287	3	19454	50	CPE,ITPR2,SLC1A3
3.747e-02	-3.28	DCC mediated attractive signaling	REACTOME pathways	R-HSA-418885	14	1	10285	28	ABLIM1
3.747e-02	-3.28	SHC1 events in ERBB4 signaling	REACTOME pathways	R-HSA-1250347	14	1	10285	28	NRG3
3.754e-02	-3.28	basal plasma membrane	cellular component	GO:0009925	288	3	19108	49	SLC1A3,AQP4,SLC4A4
3.756e-02	-3.28	ANKRD26 (ankyrin repeat domain containing 26)	protein interactions	22852	119	2	19454	50	NTRK2,PARD3
3.771e-02	-3.28	protein localization to membrane	biological process	GO:0072657	462	4	18204	50	MACF1,CPE,PARD3,TNIK
3.779e-02	-3.28	negative regulation of sodium ion transmembrane transporter activity	biological process	GO:2000650	14	1	18204	50	ATP1A2
3.779e-02	-3.28	cerebrospinal fluid circulation	biological process	GO:0090660	14	1	18204	50	AQP4
3.779e-02	-3.28	mechanosensory behavior	biological process	GO:0007638	14	1	18204	50	SLC1A3
3.779e-02	-3.28	cellular response to forskolin	biological process	GO:1904322	14	1	18204	50	ADCY2
3.779e-02	-3.28	response to forskolin	biological process	GO:1904321	14	1	18204	50	ADCY2
3.779e-02	-3.28	cellular response to ethanol	biological process	GO:0071361	14	1	18204	50	ITPR2
3.779e-02	-3.28	relaxation of cardiac muscle	biological process	GO:0055119	14	1	18204	50	ATP1A2
3.779e-02	-3.28	glutathione biosynthetic process	biological process	GO:0006750	14	1	18204	50	SLC1A2
3.779e-02	-3.28	cellular response to purine-containing compound	biological process	GO:0071415	14	1	18204	50	RYR3
3.780e-02	-3.28	axolemma	cellular component	GO:0030673	15	1	19108	49	SLC1A2
3.788e-02	-3.27	XIRP1 (xin actin binding repeat containing 1)	protein interactions	165904	15	1	19454	50	NEBL
3.788e-02	-3.27	TESPA1 (thymocyte expressed, positive selection associated 1)	protein interactions	9840	15	1	19454	50	ITPR2
3.788e-02	-3.27	IGSF1 (immunoglobulin superfamily member 1)	protein interactions	3547	15	1	19454	50	BMPR1B
3.788e-02	-3.27	PCSK1N (proprotein convertase subtilisin/kexin type 1 inhibitor)	protein interactions	27344	15	1	19454	50	MGAT4C
3.788e-02	-3.27	TAFA5 (TAFA chemokine like family member 5)	protein interactions	25817	15	1	19454	50	NEBL
3.788e-02	-3.27	RNASE13 (ribonuclease A family member 13 (inactive))	protein interactions	440163	15	1	19454	50	CPE
3.794e-02	-3.27	rhythmic process	biological process	GO:0048511	270	3	18204	50	RORA,NTRK2,BMPR1B
3.810e-02	-3.27	CEP128 (centrosomal protein 128)	protein interactions	145508	289	3	19454	50	ABLIM1,SORBS1,NEBL
3.829e-02	-3.26	SH3	prosite domains	PS50002	222	3	12186	41	SORBS1,NEBL,MACF1
3.838e-02	-3.26	response to organonitrogen compound	biological process	GO:0010243	915	6	18204	50	SORBS1,RYR3,SLC1A2,TNIK,ITPR2,SLC1A3
3.840e-02	-3.26	KIF14 (kinesin family member 14)	protein interactions	9928	1803	9	19454	50	ITPR2,SLC1A3,ABLIM1,SORBS1,MACF1,PARD3,NEBL,MSI2,SOX5
3.856e-02	-3.26	dendrite development	biological process	GO:0016358	113	2	18204	50	CTNND2,CTNNA2
3.871e-02	-3.25	Signalling by NGF	REACTOME pathways	R-HSA-166520	477	4	10285	28	ADCY2,ITPR2,NTRK2,NRG3
3.881e-02	-3.25	bone-humerus-Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour	COSMIC cancer mutations	bone-humerus-Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour	107	2	16828	49	NEBL,PARD3B
3.898e-02	-3.24	cytoskeleton	cellular component	GO:0005856	2412	11	19108	49	PARD3,TNIK,ABLIM1,NEBL,CTNNA2,MACF1,FBXL7,FMN2,DTNA,PPP2R2B,SORBS1
3.908e-02	-3.24	neurexin family protein binding	molecular function	GO:0042043	15	1	18094	48	CPE
3.908e-02	-3.24	tropomyosin binding	molecular function	GO:0005523	15	1	18094	48	NEBL
3.908e-02	-3.24	filamin binding	molecular function	GO:0031005	15	1	18094	48	NEBL
3.908e-02	-3.24	phosphatidylglycerol binding	molecular function	GO:1901611	15	1	18094	48	PITPNC1
3.930e-02	-3.24	BRK1 (BRICK1 subunit of SCAR/WAVE actin nucleating complex)	protein interactions	55845	122	2	19454	50	NHSL1,DTNA
3.943e-02	-3.23	dermatan sulfate biosynthesis	BIOCYC pathways	HUMAN_PWY-6571	12	1	902	3	CSGALNACT1
3.943e-02	-3.23	human chr13q31.3	chromosome location	human chr13q31.3	21	1	26134	50	GPC5
3.943e-02	-3.23	human chr4q32.3	chromosome location	human chr4q32.3	21	1	26134	50	CPE
3.943e-02	-3.23	human chr10q23.1	chromosome location	human chr10q23.1	21	1	26134	50	NRG3
3.947e-02	-3.23	pulmonary_blastoma	COSMIC cancer mutations	pulmonary_blastoma	648	5	16828	49	BMPR1B,NTM,ATP13A4,TRPS1,NEBL
3.947e-02	-3.23	pleura-pulmonary_blastoma	COSMIC cancer mutations	pleura-pulmonary_blastoma	648	5	16828	49	ATP13A4,NTM,NEBL,TRPS1,BMPR1B
3.965e-02	-3.23	mRNA surveillance pathway	KEGG pathways	hsa03015	91	2	7161	25	MSI2,PPP2R2B
3.965e-02	-3.23	mRNA surveillance pathway	KEGG pathways	ko03015	91	2	7161	25	PPP2R2B,MSI2
3.972e-02	-3.23	Cation_ATPase_C	pfam domains	PF00689	15	1	17795	48	ATP1A2
3.972e-02	-3.23	CNH	pfam domains	PF00780	15	1	17795	48	TNIK
3.972e-02	-3.23	FH2	pfam domains	PF02181	15	1	17795	48	FMN2
3.975e-02	-3.23	Znf_GATA	interpro domains	IPR000679	15	1	18521	50	TRPS1
3.975e-02	-3.23	ATPase_P-typ_cation-transptr_C	interpro domains	IPR006068	15	1	18521	50	ATP1A2
3.975e-02	-3.23	FH2_Formin_sf	interpro domains	IPR042201	15	1	18521	50	FMN2
3.975e-02	-3.23	FH2_Formin	interpro domains	IPR015425	15	1	18521	50	FMN2
3.975e-02	-3.23	CNH_dom	interpro domains	IPR001180	15	1	18521	50	TNIK
3.988e-02	-3.22	PAX7 (paired box 7)	protein interactions	5081	123	2	19454	50	NFIA,TRPS1
3.990e-02	-3.22	Glycerol uptake facilitator protein	gene3d domains	1.20.1080.10	14	1	14470	42	AQP4
4.008e-02	-3.22	learning or memory	biological process	GO:0007611	276	3	18204	50	NTRK2,ATP1A2,PTPRZ1
4.008e-02	-3.22	transcription cis-regulatory region binding	molecular function	GO:0000976	1485	8	18094	48	RFX4,GLIS3,RORA,ZBTB20,TRPS1,NPAS3,SOX5,NFIA
4.009e-02	-3.22	Inhibition of adenylate cyclase pathway	REACTOME pathways	R-HSA-997269	15	1	10285	28	ADCY2
4.009e-02	-3.22	N-Glycan antennae elongation	REACTOME pathways	R-HSA-975577	15	1	10285	28	MGAT4C
4.009e-02	-3.22	ERBB2 Regulates Cell Motility	REACTOME pathways	R-HSA-6785631	15	1	10285	28	NRG3
4.009e-02	-3.22	Adenylate cyclase inhibitory pathway	REACTOME pathways	R-HSA-170670	15	1	10285	28	ADCY2
4.027e-02	-3.21	postsynaptic density, intracellular component	cellular component	GO:0099092	16	1	19108	49	TNIK
4.028e-02	-3.21	phospholipid binding	molecular function	GO:0005543	489	4	18094	48	PITPNC1,ITPR2,PARD3,PARD3B
4.035e-02	-3.21	transcription regulatory region nucleic acid binding	molecular function	GO:0001067	1487	8	18094	48	RFX4,GLIS3,RORA,TRPS1,NPAS3,SOX5,ZBTB20,NFIA
4.035e-02	-3.21	TWIST2 (twist family bHLH transcription factor 2)	protein interactions	117581	16	1	19454	50	ZBTB20
4.035e-02	-3.21	GALNT13 (polypeptide N-acetylgalactosaminyltransferase 13)	protein interactions	114805	16	1	19454	50	TNIK
4.035e-02	-3.21	SAPCD1 (suppressor APC domain containing 1)	protein interactions	401251	16	1	19454	50	CTNNA2
4.035e-02	-3.21	CDH12 (cadherin 12)	protein interactions	1010	16	1	19454	50	CTNNA2
4.035e-02	-3.21	ORM2 (orosomucoid 2)	protein interactions	5005	16	1	19454	50	PPP2R2B
4.035e-02	-3.21	AMMECR1L (AMMECR1 like)	protein interactions	83607	16	1	19454	50	MACF1
4.035e-02	-3.21	FNDC8 (fibronectin type III domain containing 8)	protein interactions	54752	16	1	19454	50	SPARCL1
4.035e-02	-3.21	Sumo3 (small ubiquitin-like modifier 3)	protein interactions	20610	16	1	19454	50	ITPR2
4.043e-02	-3.21	exit from mitosis	biological process	GO:0010458	15	1	18204	50	NFIA
4.043e-02	-3.21	regulation of neuron projection arborization	biological process	GO:0150011	15	1	18204	50	MACF1
4.043e-02	-3.21	peripheral nervous system neuron differentiation	biological process	GO:0048934	15	1	18204	50	NTRK2
4.043e-02	-3.21	negative regulation of sodium ion transmembrane transport	biological process	GO:1902306	15	1	18204	50	ATP1A2
4.043e-02	-3.21	response to caffeine	biological process	GO:0031000	15	1	18204	50	RYR3
4.043e-02	-3.21	sarcoplasmic reticulum calcium ion transport	biological process	GO:0070296	15	1	18204	50	RYR3
4.043e-02	-3.21	peripheral nervous system neuron development	biological process	GO:0048935	15	1	18204	50	NTRK2
4.043e-02	-3.21	cerebellar Purkinje cell layer formation	biological process	GO:0021694	15	1	18204	50	RORA
4.043e-02	-3.21	synapse maturation	biological process	GO:0060074	15	1	18204	50	NFIA
4.043e-02	-3.21	neuroblast division	biological process	GO:0055057	15	1	18204	50	SOX5
4.043e-02	-3.21	protein homotrimerization	biological process	GO:0070207	15	1	18204	50	SLC1A2
4.043e-02	-3.21	intracellular potassium ion homeostasis	biological process	GO:0030007	15	1	18204	50	ATP1A2
4.043e-02	-3.21	positive regulation of glycogen biosynthetic process	biological process	GO:0045725	15	1	18204	50	SORBS1
4.045e-02	-3.21	GnRH signaling pathway	KEGG pathways	ko04912	92	2	7161	25	ADCY2,ITPR2
4.045e-02	-3.21	GnRH signaling pathway	KEGG pathways	hsa04912	92	2	7161	25	ADCY2,ITPR2
4.047e-02	-3.21	PSME2 (proteasome activator subunit 2)	protein interactions	5721	124	2	19454	50	PPP2R2B,PARD3
4.079e-02	-3.20	SP7 (Sp7 transcription factor)	protein interactions	121340	297	3	19454	50	TRPS1,SOX5,NFIA
4.079e-02	-3.20	TJP1 (tight junction protein 1)	protein interactions	7082	297	3	19454	50	NEBL,PARD3,DTNA
4.080e-02	-3.20	actin filament organization	biological process	GO:0007015	278	3	18204	50	NEBL,FMN2,SORBS1
4.106e-02	-3.19	oligoastrocytoma_Grade_III	COSMIC cancer mutations	oligoastrocytoma_Grade_III	263	3	16828	49	SLC1A2,SOX5,RYR3
4.117e-02	-3.19	secondary active transmembrane transporter activity	molecular function	GO:0015291	289	3	18094	48	SLC4A4,SLC1A2,SLC1A3
4.128e-02	-3.19	positive regulation of cellular process	biological process	GO:0048522	5719	22	18204	50	MAML2,MACF1,SOX5,PTPRZ1,FMN2,NTRK2,NFIA,ZBTB20,RFX4,SORBS1,GPM6A,PARD3,BMPR1B,TNIK,SLC1A2,GLIS3,NPAS3,RORA,SLC4A4,GPC5,SLC1A3,FUT9
4.134e-02	-3.19	HCO3TRNSPORT	prints domains	PR01231	10	1	5227	22	SLC4A4
4.145e-02	-3.18	skin-acral-malignant_melanoma	COSMIC cancer mutations	skin-acral-malignant_melanoma	264	3	16828	49	PARD3,CDH20,FMN2
4.148e-02	-3.18	bicellular tight junction	cellular component	GO:0005923	126	2	19108	49	PARD3B,PARD3
4.163e-02	-3.18	water channel activity	molecular function	GO:0015250	16	1	18094	48	AQP4
4.163e-02	-3.18	oxysterol binding	molecular function	GO:0008142	16	1	18094	48	RORA
4.163e-02	-3.18	adenylate cyclase activity	molecular function	GO:0004016	16	1	18094	48	ADCY2
4.166e-02	-3.18	SYP (synaptophysin)	protein interactions	6855	126	2	19454	50	PITPNC1,GPM6A
4.170e-02	-3.18	synapse assembly	biological process	GO:0007416	118	2	18204	50	NRG3,GPM6A
4.193e-02	-3.17	cell surface receptor signaling pathway	biological process	GO:0007166	1992	10	18204	50	CTNND2,NFIA,CPE,NTRK2,NRG3,BMPR1B,TNIK,SORBS1,MAML2,MACF1
4.212e-02	-3.17	SLC-mediated transmembrane transport	REACTOME pathways	R-HSA-425407	287	3	10285	28	SLC1A3,SLC1A2,SLC4A4
4.223e-02	-3.16	large_intestine-adenoma	COSMIC cancer mutations	large_intestine-adenoma	266	3	16828	49	SOX5,RYR3,CDH20
4.226e-02	-3.16	PAX9 (paired box 9)	protein interactions	5083	127	2	19454	50	NFIA,TRPS1
4.235e-02	-3.16	CarboxyPept-like_regulatory	interpro domains	IPR008969	16	1	18521	50	CPE
4.240e-02	-3.16	ZnF_GATA	smart domains	SM00401	12	1	9717	35	TRPS1
4.240e-02	-3.16	DWA	smart domains	SM00523	12	1	9717	35	NFIA
4.250e-02	-3.16	lung-middle_lobe-carcinoma-adenocarcinoma	COSMIC cancer mutations	lung-middle_lobe-carcinoma-adenocarcinoma	1368	8	16828	49	MACF1,CPE,CTNND2,ATP1A2,ATP13A4,RYR3,PARD3B,ITPR2
4.267e-02	-3.15	neuron projection terminus	cellular component	GO:0044306	128	2	19108	49	NTRK2,SLC1A2
4.269e-02	-3.15	Formin, FH2 domain	gene3d domains	1.20.58.2220	15	1	14470	42	FMN2
4.271e-02	-3.15	GRB2 events in ERBB2 signaling	REACTOME pathways	R-HSA-1963640	16	1	10285	28	NRG3
4.271e-02	-3.15	PI3K events in ERBB2 signaling	REACTOME pathways	R-HSA-1963642	16	1	10285	28	NRG3
4.271e-02	-3.15	PKA activation	REACTOME pathways	R-HSA-163615	16	1	10285	28	ADCY2
4.274e-02	-3.15	adenoid_cystic_carcinoma	COSMIC cancer mutations	adenoid_cystic_carcinoma	1123	7	16828	49	TNIK,RYR3,NTRK2,RORA,MGAT4C,MAML2,CTNND2
4.282e-02	-3.15	SEPSECS (Sep (O-phosphoserine) tRNA:Sec (selenocysteine) tRNA synthase)	protein interactions	51091	17	1	19454	50	ABLIM1
4.282e-02	-3.15	TAGAP (T cell activation RhoGTPase activating protein)	protein interactions	117289	17	1	19454	50	DTNA
4.282e-02	-3.15	Shcbp1 (Shc SH2-domain binding protein 1)	protein interactions	20419	17	1	19454	50	GPC5
4.282e-02	-3.15	PAX4 (paired box 4)	protein interactions	5078	17	1	19454	50	NTM
4.282e-02	-3.15	RASL12 (RAS like family 12)	protein interactions	51285	17	1	19454	50	BMPR1B
4.282e-02	-3.15	NOTCH4 (notch receptor 4)	protein interactions	4855	17	1	19454	50	MAML2
4.282e-02	-3.15	DPP6 (dipeptidyl peptidase like 6)	protein interactions	1804	17	1	19454	50	GPM6A
4.282e-02	-3.15	MSANTD2 (Myb/SANT DNA binding domain containing 2)	protein interactions	79684	17	1	19454	50	SOX5
4.282e-02	-3.15	Sqstm1 (sequestosome 1)	protein interactions	18412	17	1	19454	50	BMPR1B
4.285e-02	-3.15	PDZ	pfam domains	PF00595	122	2	17795	48	PARD3,PARD3B
4.286e-02	-3.15	TEAD2 (TEA domain transcription factor 2)	protein interactions	8463	128	2	19454	50	TRPS1,ZBTB20
4.286e-02	-3.15	ATF7IP (activating transcription factor 7 interacting protein)	protein interactions	55729	128	2	19454	50	MACF1,SOX5
4.286e-02	-3.15	MYB (MYB proto-oncogene, transcription factor)	protein interactions	4602	128	2	19454	50	NFIA,TRPS1
4.289e-02	-3.15	CARBOXYPEPT_ZN_1	prosite domains	PS00132	13	1	12186	41	CPE
4.289e-02	-3.15	CARBOXYPEPT_ZN_2	prosite domains	PS00133	13	1	12186	41	CPE
4.297e-02	-3.15	RAC1 (Rac family small GTPase 1)	protein interactions	5879	1005	6	19454	50	FMN2,SLC1A3,PARD3,PPP2R2B,MACF1,DTNA
4.302e-02	-3.15	acral	COSMIC cancer mutations	acral	268	3	16828	49	PARD3,CDH20,FMN2
4.307e-02	-3.14	regulation of amino acid import across plasma membrane	biological process	GO:0010958	16	1	18204	50	ATP1A2
4.307e-02	-3.14	regulation of amino acid transmembrane transport	biological process	GO:1903789	16	1	18204	50	ATP1A2
4.307e-02	-3.14	cardiac left ventricle morphogenesis	biological process	GO:0003214	16	1	18204	50	CPE
4.307e-02	-3.14	regulation of respiratory system process	biological process	GO:0044065	16	1	18204	50	ATP1A2
4.307e-02	-3.14	nonribosomal peptide biosynthetic process	biological process	GO:0019184	16	1	18204	50	SLC1A2
4.307e-02	-3.14	insulin metabolic process	biological process	GO:1901142	16	1	18204	50	CPE
4.307e-02	-3.14	fucose metabolic process	biological process	GO:0006004	16	1	18204	50	FUT9
4.307e-02	-3.14	locomotory exploration behavior	biological process	GO:0035641	16	1	18204	50	ATP1A2
4.307e-02	-3.14	non-proteinogenic amino acid biosynthetic process	biological process	GO:0170043	16	1	18204	50	SLC1A3
4.311e-02	-3.14	human chr5p15.31	chromosome location	human chr5p15.31	23	1	26134	50	ADCY2
4.346e-02	-3.14	CHD7 (chromodomain helicase DNA binding protein 7)	protein interactions	55636	129	2	19454	50	SOX5,ZBTB20
4.352e-02	-3.13	homeostatic process	biological process	GO:0042592	1456	8	18204	50	SLC4A4,RORA,RYR3,SLC1A3,ZBTB20,ATP13A4,AQP4,ATP1A2
4.366e-02	-3.13	channel activity	molecular function	GO:0015267	502	4	18094	48	GPM6A,ITPR2,AQP4,RYR3
4.369e-02	-3.13	Circadian entrainment	KEGG pathways	hsa04713	96	2	7161	25	RYR3,ADCY2
4.369e-02	-3.13	Circadian entrainment	KEGG pathways	ko04713	96	2	7161	25	ADCY2,RYR3
4.379e-02	-3.13	export from cell	biological process	GO:0140352	485	4	18204	50	SLC4A4,CPE,NTRK2,ATP1A2
4.388e-02	-3.13	Z disc	cellular component	GO:0030018	130	2	19108	49	NEBL,RYR3
4.392e-02	-3.13	passive transmembrane transporter activity	molecular function	GO:0022803	503	4	18094	48	GPM6A,AQP4,ITPR2,RYR3
4.400e-02	-3.12	basal part of cell	cellular component	GO:0045178	307	3	19108	49	SLC1A3,SLC4A4,AQP4
4.407e-02	-3.12	PKP1 (plakophilin 1)	protein interactions	5317	130	2	19454	50	CSGALNACT1,PPP2R2B
4.417e-02	-3.12	transmembrane receptor protein phosphatase activity	molecular function	GO:0019198	17	1	18094	48	PTPRZ1
4.417e-02	-3.12	transmembrane receptor protein tyrosine phosphatase activity	molecular function	GO:0005001	17	1	18094	48	PTPRZ1
4.432e-02	-3.12	Bone Morphogenic Protein (BMP) Signalling and Regulation	WikiPathways	WP1425	12	1	5310	20	BMPR1B
4.432e-02	-3.12	MFAP5-mediated ovarian cancer cell motility and invasiveness	WikiPathways	WP3301	12	1	5310	20	RYR3
4.445e-02	-3.11	Glycosaminoglycan metabolism	REACTOME pathways	R-HSA-1630316	124	2	10285	28	CSGALNACT1,GPC5
4.449e-02	-3.11	tight junction	cellular component	GO:0070160	131	2	19108	49	PARD3B,PARD3
4.452e-02	-3.11	Inflammatory mediator regulation of TRP channels	KEGG pathways	hsa04750	97	2	7161	25	ITPR2,ADCY2
4.452e-02	-3.11	Inflammatory mediator regulation of TRP channels	KEGG pathways	ko04750	97	2	7161	25	ITPR2,ADCY2
4.468e-02	-3.11	TRPS1 (transcriptional repressor GATA binding 1)	protein interactions	7227	131	2	19454	50	NFIA,SOX5
4.468e-02	-3.11	NCOA2 (nuclear receptor coactivator 2)	protein interactions	10499	131	2	19454	50	RORA,NFIA
4.468e-02	-3.11	ZNF609 (zinc finger protein 609)	protein interactions	23060	131	2	19454	50	NFIA,SOX5
4.472e-02	-3.11	middle_lobe	COSMIC cancer mutations	middle_lobe	1382	8	16828	49	MACF1,CPE,ATP1A2,CTNND2,PARD3B,ATP13A4,RYR3,ITPR2
4.490e-02	-3.10	ZZ	pfam domains	PF00569	17	1	17795	48	DTNA
4.490e-02	-3.10	Carb_anhydrase	pfam domains	PF00194	17	1	17795	48	PTPRZ1
4.493e-02	-3.10	CA_dom	interpro domains	IPR001148	17	1	18521	50	PTPRZ1
4.493e-02	-3.10	A/G_cyclase_CS	interpro domains	IPR018297	17	1	18521	50	ADCY2
4.493e-02	-3.10	CA_dom_sf	interpro domains	IPR036398	17	1	18521	50	PTPRZ1
4.507e-02	-3.10	ductal_carcinoma	COSMIC cancer mutations	ductal_carcinoma	15798	49	16828	49	PTPRZ1,FBXL7,ITPR2,FUT9,NRG3,NKAIN3,ADCY2,NEBL,CPE,CTNND2,SOX5,CDH20,TNIK,SLC4A4,RORA,ABLIM1,MGAT4C,FMN2,ATP13A4,RYR3,PITPNC1,ATP1A2,TRPS1,PARD3,NTRK2,SORBS1,LSAMP,CSGALNACT1,SFXN5,PARD3B,NFIA,BMPR1B,SLC1A2,DTNA,GLIS3,RFX4,GPC5,PPP2R2B,AQP4,NHSL1,NPAS3,MSI2,NTM,ZBTB20,SLC1A3,MACF1,GPM6A,SPARCL1,MAML2
4.519e-02	-3.10	protein phosphatase type 2A complex	cellular component	GO:0000159	18	1	19108	49	PPP2R2B
4.529e-02	-3.09	ACAP1 (ArfGAP with coiled-coil, ankyrin repeat and PH domains 1)	protein interactions	9744	18	1	19454	50	NEBL
4.529e-02	-3.09	Cnot2 (CCR4-NOT transcription complex, subunit 2)	protein interactions	72068	18	1	19454	50	MACF1
4.529e-02	-3.09	KLHL1 (kelch like family member 1)	protein interactions	57626	18	1	19454	50	BMPR1B
4.529e-02	-3.09	SERTAD4 (SERTA domain containing 4)	protein interactions	56256	18	1	19454	50	PPP2R2B
4.529e-02	-3.09	Tgfbr1 (transforming growth factor, beta receptor I)	protein interactions	21812	18	1	19454	50	BMPR1B
4.529e-02	-3.09	TTC29 (tetratricopeptide repeat domain 29)	protein interactions	83894	18	1	19454	50	MACF1
4.529e-02	-3.09	OPCML (opioid binding protein/cell adhesion molecule like)	protein interactions	4978	18	1	19454	50	NTM
4.529e-02	-3.09	NKIRAS1 (NFKB inhibitor interacting Ras like 1)	protein interactions	28512	18	1	19454	50	BMPR1B
4.529e-02	-3.09	NECTIN1 (nectin cell adhesion molecule 1)	protein interactions	5818	18	1	19454	50	PARD3
4.530e-02	-3.09	IVL (involucrin)	protein interactions	3713	132	2	19454	50	PPP2R2B,CSGALNACT1
4.532e-02	-3.09	PKA activation in glucagon signalling	REACTOME pathways	R-HSA-164378	17	1	10285	28	ADCY2
4.532e-02	-3.09	PKA-mediated phosphorylation of CREB	REACTOME pathways	R-HSA-111931	17	1	10285	28	ADCY2
4.532e-02	-3.09	TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)	REACTOME pathways	R-HSA-2173791	17	1	10285	28	PARD3
4.532e-02	-3.09	Elevation of cytosolic Ca2+ levels	REACTOME pathways	R-HSA-139853	17	1	10285	28	ITPR2
4.535e-02	-3.09	Estrogen signaling pathway	KEGG pathways	hsa04915	98	2	7161	25	ITPR2,ADCY2
4.535e-02	-3.09	Estrogen signaling pathway	KEGG pathways	ko04915	98	2	7161	25	ITPR2,ADCY2
4.557e-02	-3.09	salivary_gland	COSMIC cancer mutations	salivary_gland	1139	7	16828	49	CTNND2,MGAT4C,MAML2,NTRK2,RORA,TNIK,RYR3
4.557e-02	-3.09	cytoskeletal protein binding	molecular function	GO:0008092	989	6	18094	48	CTNNA2,MACF1,SORBS1,ABLIM1,FMN2,NEBL
4.560e-02	-3.09	action potential	biological process	GO:0001508	124	2	18204	50	NTRK2,ATP1A2
4.560e-02	-3.09	positive regulation of lipid metabolic process	biological process	GO:0045834	124	2	18204	50	ZBTB20,SORBS1
4.570e-02	-3.09	retinal rod cell differentiation	biological process	GO:0060221	17	1	18204	50	NTRK2
4.570e-02	-3.09	membrane depolarization during cardiac muscle cell action potential	biological process	GO:0086012	17	1	18204	50	ATP1A2
4.570e-02	-3.09	positive regulation of glycogen metabolic process	biological process	GO:0070875	17	1	18204	50	SORBS1
4.570e-02	-3.09	viral genome replication	biological process	GO:0019079	17	1	18204	50	NFIA
4.570e-02	-3.09	protein trimerization	biological process	GO:0070206	17	1	18204	50	SLC1A2
4.570e-02	-3.09	cGMP metabolic process	biological process	GO:0046068	17	1	18204	50	RORA
4.570e-02	-3.09	fucosylation	biological process	GO:0036065	17	1	18204	50	FUT9
4.570e-02	-3.09	cell communication by electrical coupling involved in cardiac conduction	biological process	GO:0086064	17	1	18204	50	ATP1A2
4.570e-02	-3.09	cell migration in hindbrain	biological process	GO:0021535	17	1	18204	50	CTNNA2
4.570e-02	-3.09	microvillus assembly	biological process	GO:0030033	17	1	18204	50	TNIK
4.570e-02	-3.09	cellular response to ATP	biological process	GO:0071318	17	1	18204	50	RYR3
4.570e-02	-3.09	T-helper 17 type immune response	biological process	GO:0072538	17	1	18204	50	RORA
4.570e-02	-3.09	heparin metabolic process	biological process	GO:0030202	17	1	18204	50	CSGALNACT1
4.570e-02	-3.09	ureter development	biological process	GO:0072189	17	1	18204	50	NFIA
4.585e-02	-3.08	ErbB receptor signaling network	Pathway Interaction DB	erbb_network_pathway	13	1	2226	8	NRG3
4.607e-02	-3.08	response to hypoxia	biological process	GO:0001666	292	3	18204	50	RORA,FMN2,ITPR2
4.626e-02	-3.07	actomyosin structure organization	biological process	GO:0031032	125	2	18204	50	SORBS1,NEBL
4.631e-02	-3.07	modulation of chemical synaptic transmission	biological process	GO:0050804	494	4	18204	50	NRG3,ATP1A2,NTRK2,SLC1A3
4.631e-02	-3.07	cellular response to growth factor stimulus	biological process	GO:0071363	494	4	18204	50	NFIA,NTRK2,BMPR1B,SOX5
4.660e-02	-3.07	regulation of trans-synaptic signaling	biological process	GO:0099177	495	4	18204	50	NRG3,ATP1A2,NTRK2,SLC1A3
4.671e-02	-3.06	transmembrane receptor protein tyrosine kinase activator activity	molecular function	GO:0030297	18	1	18094	48	NRG3
4.671e-02	-3.06	phosphatidylcholine transporter activity	molecular function	GO:0008525	18	1	18094	48	PITPNC1
4.687e-02	-3.06	SH3DOMAIN	prints domains	PR00452	83	2	5227	22	SORBS1,NEBL
4.716e-02	-3.05	SOX15 (SRY-box transcription factor 15)	protein interactions	6665	135	2	19454	50	TRPS1,NFIA
4.716e-02	-3.05	FOXP1 (forkhead box P1)	protein interactions	27086	135	2	19454	50	SOX5,NFIA
4.722e-02	-3.05	central_nervous_system-brain-glioma-astrocytoma_Grade_IV	COSMIC cancer mutations	central_nervous_system-brain-glioma-astrocytoma_Grade_IV	15813	49	16828	49	NFIA,BMPR1B,DTNA,SLC1A2,PARD3B,GLIS3,CSGALNACT1,LSAMP,SFXN5,SLC1A3,ZBTB20,MSI2,NTM,MAML2,SPARCL1,MACF1,GPM6A,PPP2R2B,GPC5,RFX4,NHSL1,NPAS3,AQP4,ABLIM1,SLC4A4,RORA,CDH20,TNIK,MGAT4C,NKAIN3,FUT9,NRG3,ITPR2,PTPRZ1,FBXL7,CTNND2,SOX5,CPE,NEBL,ADCY2,TRPS1,PARD3,SORBS1,NTRK2,FMN2,RYR3,ATP13A4,ATP1A2,PITPNC1
4.728e-02	-3.05	localization	biological process	GO:0051179	4474	18	18204	50	TNIK,SLC1A2,PITPNC1,SFXN5,AQP4,GPM6A,PARD3,ITPR2,SLC1A3,SLC4A4,RYR3,PARD3B,FMN2,ATP1A2,NTRK2,MACF1,ATP13A4,CPE
4.748e-02	-3.05	Guanylate_cyc	pfam domains	PF00211	18	1	17795	48	ADCY2
4.752e-02	-3.05	Leu-rich_rpt_Cys-con_subtyp	interpro domains	IPR006553	18	1	18521	50	FBXL7
4.752e-02	-3.05	Nucleotide_cyclase	interpro domains	IPR029787	18	1	18521	50	ADCY2
4.752e-02	-3.05	A/G_cyclase	interpro domains	IPR001054	18	1	18521	50	ADCY2
4.760e-02	-3.05	cell-cell junction assembly	biological process	GO:0007043	127	2	18204	50	CDH20,PARD3
4.760e-02	-3.05	response to amino acid	biological process	GO:0043200	127	2	18204	50	NTRK2,SLC1A2
4.761e-02	-3.04	postsynaptic density	cellular component	GO:0014069	317	3	19108	49	TNIK,NTRK2,CTNND2
4.764e-02	-3.04	cation-transporting ATPase complex	cellular component	GO:0090533	19	1	19108	49	ATP1A2
4.764e-02	-3.04	postsynaptic specialization, intracellular component	cellular component	GO:0099091	19	1	19108	49	TNIK
4.764e-02	-3.04	parallel fiber to Purkinje cell synapse	cellular component	GO:0098688	19	1	19108	49	GPM6A
4.764e-02	-3.04	positive regulation of nervous system development	biological process	GO:0051962	296	3	18204	50	MACF1,PTPRZ1,NTRK2
4.768e-02	-3.04	primary_central_nervous_system_lymphoma	COSMIC cancer mutations	primary_central_nervous_system_lymphoma	683	5	16828	49	NRG3,PARD3B,MACF1,PARD3,ZBTB20
4.768e-02	-3.04	haematopoietic_and_lymphoid_tissue-central_nervous_system-lymphoid_neoplasm-primary_central_nervous_system_lymphoma	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue-central_nervous_system-lymphoid_neoplasm-primary_central_nervous_system_lymphoma	683	5	16828	49	ZBTB20,PARD3,PARD3B,MACF1,NRG3
4.772e-02	-3.04	haematopoietic_and_lymphoid_tissue-abdomen-lymphoid_neoplasm-diffuse_large_B_cell_lymphoma	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue-abdomen-lymphoid_neoplasm-diffuse_large_B_cell_lymphoma	120	2	16828	49	FMN2,CTNND2
4.774e-02	-3.04	INKA1 (inka box actin regulator 1)	protein interactions	389119	19	1	19454	50	ZBTB20
4.774e-02	-3.04	GCHFR (GTP cyclohydrolase I feedback regulator)	protein interactions	2644	19	1	19454	50	NEBL
4.774e-02	-3.04	RIT2 (Ras like without CAAX 2)	protein interactions	6014	19	1	19454	50	DTNA
4.774e-02	-3.04	CNTNAP4 (contactin associated protein family member 4)	protein interactions	85445	19	1	19454	50	MACF1
4.774e-02	-3.04	SPZ1 (spermatogenic leucine zipper 1)	protein interactions	84654	19	1	19454	50	DTNA
4.774e-02	-3.04	PHYHIPL (phytanoyl-CoA 2-hydroxylase interacting protein like)	protein interactions	84457	19	1	19454	50	GPM6A
4.774e-02	-3.04	PLA2G4E (phospholipase A2 group IVE)	protein interactions	123745	19	1	19454	50	PPP2R2B
4.774e-02	-3.04	C3orf62 (chromosome 3 open reading frame 62)	protein interactions	375341	19	1	19454	50	ATP1A2
4.774e-02	-3.04	TNR (tenascin R)	protein interactions	7143	19	1	19454	50	PTPRZ1
4.788e-02	-3.04	Retrograde endocannabinoid signaling	KEGG pathways	hsa04723	101	2	7161	25	ITPR2,ADCY2
4.788e-02	-3.04	Retrograde endocannabinoid signaling	KEGG pathways	ko04723	101	2	7161	25	ADCY2,ITPR2
4.793e-02	-3.04	Cell-type Dependent Selectivity of CCK2R Signaling	WikiPathways	WP3679	13	1	5310	20	RYR3
4.802e-02	-3.04	PK_Tyr_Ser-Thr	pfam domains	PF07714	130	2	17795	48	NTRK2,BMPR1B
4.804e-02	-3.04	muscle system process	biological process	GO:0003012	297	3	18204	50	RYR3,DTNA,ATP1A2
4.824e-02	-3.03	Alpha carbonic anhydrase	gene3d domains	3.10.200.10	17	1	14470	42	PTPRZ1
4.827e-02	-3.03	myelination	biological process	GO:0042552	128	2	18204	50	PARD3,NTRK2
4.827e-02	-3.03	carbohydrate biosynthetic process	biological process	GO:0016051	128	2	18204	50	CSGALNACT1,FUT9
4.827e-02	-3.03	glial cell development	biological process	GO:0021782	128	2	18204	50	PARD3,NTRK2
4.832e-02	-3.03	dendritic spine morphogenesis	biological process	GO:0060997	18	1	18204	50	CTNND2
4.832e-02	-3.03	positive regulation of circadian rhythm	biological process	GO:0042753	18	1	18204	50	RORA
4.832e-02	-3.03	regulation of leukocyte tethering or rolling	biological process	GO:1903236	18	1	18204	50	FUT9
4.832e-02	-3.03	positive regulation of myelination	biological process	GO:0031643	18	1	18204	50	PARD3
4.832e-02	-3.03	negative regulation of sodium ion transport	biological process	GO:0010766	18	1	18204	50	ATP1A2
4.832e-02	-3.03	negative regulation of anoikis	biological process	GO:2000811	18	1	18204	50	NTRK2
4.832e-02	-3.03	cardiac myofibril assembly	biological process	GO:0055003	18	1	18204	50	NEBL
4.842e-02	-3.03	TBL1X (transducin beta like 1 X-linked)	protein interactions	6907	137	2	19454	50	SOX5,NFIA
4.843e-02	-3.03	oligoastrocytoma_Grade_II	COSMIC cancer mutations	oligoastrocytoma_Grade_II	121	2	16828	49	DTNA,CDH20
4.859e-02	-3.02	human chr18q12.1	chromosome location	human chr18q12.1	26	1	26134	50	DTNA
4.873e-02	-3.02	Glucagon signaling pathway	KEGG pathways	ko04922	102	2	7161	25	ADCY2,ITPR2
4.873e-02	-3.02	Glucagon signaling pathway	KEGG pathways	hsa04922	102	2	7161	25	ITPR2,ADCY2
4.894e-02	-3.02	response to organophosphorus	biological process	GO:0046683	129	2	18204	50	ITPR2,RYR3
4.911e-02	-3.01	sequence-specific double-stranded DNA binding	molecular function	GO:1990837	1547	8	18094	48	RORA,GLIS3,RFX4,NFIA,SOX5,NPAS3,ZBTB20,TRPS1
4.912e-02	-3.01	dermatan sulfate biosynthesis	BIOCYC pathways	META_PWY-6571	15	1	902	3	CSGALNACT1
4.924e-02	-3.01	water transmembrane transporter activity	molecular function	GO:0005372	19	1	18094	48	AQP4
4.924e-02	-3.01	alkali metal ion binding	molecular function	GO:0031420	19	1	18094	48	ATP1A2
4.924e-02	-3.01	transmembrane receptor protein serine/threonine kinase activity	molecular function	GO:0004675	19	1	18094	48	BMPR1B
4.930e-02	-3.01	CNH	smart domains	SM00036	14	1	9717	35	TNIK
4.932e-02	-3.01	CNH	prosite domains	PS50219	15	1	12186	41	TNIK
4.932e-02	-3.01	FH2	prosite domains	PS51444	15	1	12186	41	FMN2
4.940e-02	-3.01	ACTA1 (actin alpha 1, skeletal muscle)	protein interactions	58	321	3	19454	50	MACF1,DTNA,SORBS1
4.956e-02	-3.00	bounding membrane of organelle	cellular component	GO:0098588	2198	10	19108	49	ITPR2,PPP2R2B,RYR3,ATP13A4,CSGALNACT1,FUT9,NTRK2,MGAT4C,AQP4,CPE
4.962e-02	-3.00	ensheathment of neurons	biological process	GO:0007272	130	2	18204	50	PARD3,NTRK2
4.962e-02	-3.00	axon ensheathment	biological process	GO:0008366	130	2	18204	50	NTRK2,PARD3
4.968e-02	-3.00	SPCS2 (signal peptidase complex subunit 2)	protein interactions	9789	139	2	19454	50	GPC5,MGAT4C
4.987e-02	-3.00	ligand-gated monoatomic cation channel activity	molecular function	GO:0099094	135	2	18094	48	ITPR2,RYR3