Gene Ontology Enrichment Results

Homer de novo Motif Enrichment Results
Known Motif Enrichment Results

Text file version of complete results (i.e. open with Excel)

biological process: Functional groupings of proteins (Gene Ontology)

molecular function: Mechanistic actions of proteins (Gene Ontology)

cellular component: Protein localization (Gene Ontology)

chromosome location: Genes with similar chromosome localization (NCBI Gene)

KEGG pathways: Groups of proteins in the same pathways (KEGG)

protein interactions: "Proteins interacting with a common protein (BIND, EcoCyc, HPRD)" (NCBI Gene)

interpro domains: Proteins with similar domains and features (Interpro)

pfam domains: Proteins with similar domains and features (Pfam)

smart domains: Proteins with similar domains and features (SMART)

gene3d domains: Proteins with similar domains and features (Gene3D)

prosite domains: Proteins with similar domains and features (Prosite)

prints domains: Proteins with similar domains and features (PRINTS)

MSigDB lists: "Genes sets for pathways, factor/miRNA target predictions, expression patterns, etc." (MSigDB)

BIOCYC pathways: Groups of proteins in the same pathways (BIOCYC)

COSMIC cancer mutations: Genes mutated in similar cancers (COSMIC)

GWAS genes: Genes mutated in similar diseases (GWAS Catalog)

Lipid Maps pathways: Groups of proteins in the same lipid pathways (Lipid Maps/Biosystems)

Pathway Interaction DB: Groups of proteins in the same pathways (Pathway Interaction Database)

REACTOME pathways: Groups of proteins in the same pathways (REACTOME)

SMPDB pathways: Groups of proteins in the same pathways (SMPDB)

WikiPathways: Groups of proteins in the same pathways (Wikipathways)

Enriched Categories

P-value	ln(P)	Term	GO Tree	GO ID	# of Genes in Term	# of Target Genes in Term	# of Total Genes	# of Target Genes	Common Genes
1.086e-11	-25.25	Burkitt_lymphoma	COSMIC cancer mutations	Burkitt_lymphoma	2119	26	16828	49	LSAMP,RFX4,TPD52L1,MAML2,SLC1A3,RYR3,GPM6A,PPP2R2B,BMPR1B,NHSL1,GPC5,CTNND2,NKAIN3,SASH1,NTRK2,FMN2,CSGALNACT1,SOX5,CPE,SLC1A2,ITPR2,PRKG1,FBXL7,ADCY2,NPAS3,PREX2
1.086e-11	-25.25	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-Burkitt_lymphoma	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-Burkitt_lymphoma	2119	26	16828	49	PREX2,NPAS3,ADCY2,FBXL7,PRKG1,ITPR2,SLC1A2,CPE,SOX5,FMN2,CSGALNACT1,SASH1,NTRK2,NKAIN3,CTNND2,GPC5,BMPR1B,NHSL1,GPM6A,PPP2R2B,RYR3,SLC1A3,MAML2,TPD52L1,RFX4,LSAMP
4.268e-11	-23.88	prostate-carcinoma	COSMIC cancer mutations	prostate-carcinoma	9000	47	16828	49	NEBL,CSGALNACT1,CTNND2,PTPRZ1,NKAIN3,DTNA,NTM,SASH1,NTRK2,PRKG1,TNIK,ZBTB20,RORA,MACF1,CPE,MAML2,TPD52L1,FUT9,LSAMP,TRPS1,GPM6A,NFIA,BMPR1B,QKI,SLC1A3,PARD3B,FMN2,SFXN5,SOX5,GPC5,GLIS3,MSI2,NPAS3,ADCY2,FBXL7,ABLIM1,PREX2,SLC1A2,ITPR2,PITPNC1,CDH20,RFX4,PPP2R2B,NHSL1,SPARCL1,RYR3,SORBS1
6.063e-10	-21.22	central_nervous_system-brainstem-glioma-astrocytoma_Grade_IV	COSMIC cancer mutations	central_nervous_system-brainstem-glioma-astrocytoma_Grade_IV	2531	26	16828	49	SOX5,FMN2,SFXN5,PTPRZ1,NKAIN3,SASH1,GPC5,CTNND2,ZBTB20,FBXL7,ADCY2,RORA,PREX2,PRKG1,TNIK,ITPR2,CPE,CDH20,MAML2,TPD52L1,LSAMP,QKI,GPM6A,PPP2R2B,SLC1A3,RYR3
1.443e-09	-20.36	acute_lymphoblastic_B_cell_leukaemia	COSMIC cancer mutations	acute_lymphoblastic_B_cell_leukaemia	3828	31	16828	49	MAML2,MGAT4C,LSAMP,PPP2R2B,GPM6A,NFIA,BMPR1B,SLC1A3,RYR3,NEBL,CSGALNACT1,FMN2,SOX5,GPC5,CTNND2,GLIS3,PTPRZ1,NKAIN3,NTM,NTRK2,SASH1,PRKG1,TNIK,ZBTB20,ADCY2,FBXL7,RORA,PREX2,CPE,SLC1A2,ITPR2
1.443e-09	-20.36	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-acute_lymphoblastic_B_cell_leukaemia	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-acute_lymphoblastic_B_cell_leukaemia	3828	31	16828	49	SLC1A3,RYR3,GPM6A,PPP2R2B,BMPR1B,NFIA,LSAMP,MGAT4C,MAML2,ITPR2,CPE,SLC1A2,FBXL7,ADCY2,ZBTB20,PREX2,RORA,PRKG1,TNIK,NKAIN3,PTPRZ1,NTRK2,NTM,SASH1,GPC5,CTNND2,GLIS3,SOX5,NEBL,CSGALNACT1,FMN2
1.647e-09	-20.22	brainstem	COSMIC cancer mutations	brainstem	3102	28	16828	49	ZBTB20,FBXL7,ADCY2,NPAS3,RORA,PREX2,PRKG1,TNIK,ITPR2,SLC1A2,CPE,SOX5,SFXN5,FMN2,PTPRZ1,NKAIN3,SASH1,GPC5,CTNND2,QKI,GPM6A,PPP2R2B,SLC1A3,RYR3,CDH20,MAML2,TPD52L1,LSAMP
2.096e-09	-19.98	diffuse_large_B_cell_lymphoma	COSMIC cancer mutations	diffuse_large_B_cell_lymphoma	4151	32	16828	49	TRPS1,LSAMP,CDH20,MAML2,TPD52L1,RYR3,SLC1A3,SPARCL1,QKI,PPP2R2B,GPM6A,NTRK2,SASH1,DTNA,NKAIN3,CTNND2,GPC5,SOX5,FMN2,CSGALNACT1,NEBL,ITPR2,CPE,ATP1A2,SLC1A2,RORA,PREX2,MACF1,ADCY2,FBXL7,TNIK,PRKG1
2.639e-09	-19.75	chondroblastoma	COSMIC cancer mutations	chondroblastoma	534	13	16828	49	NKAIN3,GPC5,LSAMP,CTNND2,SOX5,SFXN5,FMN2,TPD52L1,RYR3,ADCY2,PRKG1,GPM6A,PPP2R2B
4.492e-09	-19.22	central_nervous_system-brain-primitive_neuroectodermal_tumour-medulloblastoma	COSMIC cancer mutations	central_nervous_system-brain-primitive_neuroectodermal_tumour-medulloblastoma	7205	41	16828	49	LSAMP,RFX4,TRPS1,TPD52L1,MAML2,PITPNC1,RYR3,SLC1A3,SORBS1,NHSL1,NFIA,GPM6A,PPP2R2B,QKI,GLIS3,CTNND2,GPC5,NTRK2,SASH1,NTM,NKAIN3,PTPRZ1,SFXN5,FMN2,CSGALNACT1,PARD3B,NEBL,SOX5,CPE,SLC1A2,ITPR2,TNIK,PRKG1,PREX2,MACF1,ABLIM1,RORA,ADCY2,NPAS3,FBXL7,ZBTB20
7.518e-09	-18.71	angiosarcoma	COSMIC cancer mutations	angiosarcoma	2192	23	16828	49	CDH20,TPD52L1,MAML2,LSAMP,PPP2R2B,GPM6A,SLC1A3,RYR3,SOX5,NEBL,FMN2,NKAIN3,PTPRZ1,NTRK2,SASH1,GPC5,CTNND2,ADCY2,FBXL7,PREX2,PRKG1,ITPR2,SLC1A2
7.518e-09	-18.71	soft_tissue-blood_vessel-angiosarcoma	COSMIC cancer mutations	soft_tissue-blood_vessel-angiosarcoma	2192	23	16828	49	LSAMP,TPD52L1,MAML2,CDH20,SLC1A3,RYR3,PPP2R2B,GPM6A,GPC5,CTNND2,NKAIN3,PTPRZ1,NTRK2,SASH1,NEBL,FMN2,SOX5,SLC1A2,ITPR2,PRKG1,FBXL7,ADCY2,PREX2
8.890e-09	-18.54	blood_vessel	COSMIC cancer mutations	blood_vessel	2211	23	16828	49	GPM6A,PPP2R2B,RYR3,SLC1A3,CDH20,TPD52L1,MAML2,LSAMP,PREX2,FBXL7,ADCY2,PRKG1,ITPR2,SLC1A2,SOX5,FMN2,NEBL,SASH1,NTRK2,NKAIN3,PTPRZ1,CTNND2,GPC5
1.281e-08	-18.17	bone-humerus-other-chondroblastoma	COSMIC cancer mutations	bone-humerus-other-chondroblastoma	301	10	16828	49	TPD52L1,SFXN5,FMN2,PPP2R2B,GPM6A,PRKG1,SOX5,ADCY2,GPC5,NKAIN3
1.793e-08	-17.84	haematopoietic_and_lymphoid_tissue-haematopoietic_neoplasm-acute_myeloid_leukaemia_therapy_related	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue-haematopoietic_neoplasm-acute_myeloid_leukaemia_therapy_related	1523	19	16828	49	GPC5,LSAMP,CTNND2,NKAIN3,NTRK2,NEBL,FMN2,MAML2,SOX5,SLC1A3,RYR3,ITPR2,PRKG1,PPP2R2B,ADCY2,FBXL7,QKI,RORA,PREX2
1.793e-08	-17.84	acute_myeloid_leukaemia_therapy_related	COSMIC cancer mutations	acute_myeloid_leukaemia_therapy_related	1523	19	16828	49	PPP2R2B,PRKG1,PREX2,QKI,RORA,FBXL7,ADCY2,RYR3,SLC1A3,ITPR2,MAML2,FMN2,NEBL,SOX5,CTNND2,LSAMP,GPC5,NTRK2,NKAIN3
1.947e-08	-17.75	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-mantle_cell_lymphoma	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-mantle_cell_lymphoma	2737	25	16828	49	CTNND2,GPC5,NTRK2,SASH1,NKAIN3,SFXN5,FMN2,PARD3B,NEBL,SOX5,SLC1A2,CPE,ITPR2,PRKG1,PREX2,FBXL7,ADCY2,LSAMP,RFX4,TRPS1,MAML2,RYR3,SLC1A3,PPP2R2B,GPM6A
2.342e-08	-17.57	cerebellum	COSMIC cancer mutations	cerebellum	769	14	16828	49	NEBL,PARD3B,MAML2,GPC5,CTNND2,PTPRZ1,NTRK2,PRKG1,NPAS3,QKI,ABLIM1,CPE,RYR3,ITPR2
3.723e-08	-17.11	humerus	COSMIC cancer mutations	humerus	546	12	16828	49	PPP2R2B,GPM6A,PRKG1,ADCY2,GPC5,NKAIN3,TPD52L1,SFXN5,FMN2,PARD3B,NEBL,SOX5
4.446e-08	-16.93	mantle_cell_lymphoma	COSMIC cancer mutations	mantle_cell_lymphoma	2849	25	16828	49	CTNND2,GPC5,SASH1,NTRK2,NKAIN3,SFXN5,FMN2,PARD3B,NEBL,SOX5,CPE,SLC1A2,ITPR2,PRKG1,PREX2,ADCY2,FBXL7,LSAMP,TRPS1,RFX4,MAML2,RYR3,SLC1A3,GPM6A,PPP2R2B
5.448e-08	-16.73	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-diffuse_large_B_cell_lymphoma	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-diffuse_large_B_cell_lymphoma	3608	28	16828	49	PRKG1,TNIK,ADCY2,FBXL7,RORA,MACF1,PREX2,ATP1A2,SLC1A2,CPE,ITPR2,NEBL,FMN2,CSGALNACT1,SOX5,GPC5,CTNND2,NKAIN3,SASH1,GPM6A,PPP2R2B,QKI,SPARCL1,RYR3,MAML2,TPD52L1,CDH20,LSAMP
7.535e-08	-16.40	PRNP (prion protein (Kanno blood group))	protein interactions	5621	1118	15	19454	50	PTPRZ1,GPM6A,SLC1A3,TRPS1,LSAMP,NHSL1,QKI,ABLIM1,MACF1,SPARCL1,CPE,ATP1A2,MAML2,MSI2,SORBS1
8.769e-08	-16.25	nervous system development	biological process	GO:0007399	2185	21	18204	50	FUT9,NTM,RORA,SLC1A3,ATP1A2,PRKG1,PREX2,LSAMP,RFX4,NFIA,GPM6A,NTRK2,MSI2,QKI,CTNNA2,TNIK,PTPRZ1,CTNND2,BMPR1B,SOX5,SLC1A2
1.245e-07	-15.90	CTNNA1 (catenin alpha 1)	protein interactions	1495	325	9	19454	50	NEBL,SASH1,DTNA,NHSL1,SORBS1,CTNNA2,MACF1,TNIK,ABLIM1
1.593e-07	-15.65	lymphoid_neoplasm	COSMIC cancer mutations	lymphoid_neoplasm	12233	49	16828	49	CPE,ATP1A2,ZBTB20,RORA,MACF1,PRKG1,TNIK,PTPRZ1,DTNA,NKAIN3,SASH1,NTM,NTRK2,CTNND2,NEBL,CSGALNACT1,SLC1A3,QKI,GPM6A,NFIA,BMPR1B,TRPS1,LSAMP,MGAT4C,FUT9,MAML2,TPD52L1,ITPR2,SLC1A2,NPAS3,FBXL7,ADCY2,PREX2,ABLIM1,MSI2,GPC5,GLIS3,SOX5,PARD3B,FMN2,SFXN5,SORBS1,SPARCL1,RYR3,PPP2R2B,NHSL1,RFX4,PITPNC1,CDH20
2.559e-07	-15.18	upper_aerodigestive_tract-mouth-carcinoma-squamous_cell_carcinoma	COSMIC cancer mutations	upper_aerodigestive_tract-mouth-carcinoma-squamous_cell_carcinoma	6953	38	16828	49	NHSL1,PPP2R2B,GPM6A,QKI,RYR3,SORBS1,MAML2,MGAT4C,FUT9,CDH20,PITPNC1,LSAMP,TRPS1,RFX4,TNIK,PRKG1,RORA,ABLIM1,PREX2,MACF1,ZBTB20,ADCY2,FBXL7,SLC1A2,ATP1A2,ITPR2,CSGALNACT1,FMN2,SFXN5,PARD3B,NEBL,SOX5,CTNND2,GPC5,SASH1,NTM,PTPRZ1,DTNA
2.603e-07	-15.16	central_nervous_system-cerebellum-primitive_neuroectodermal_tumour-medulloblastoma-SHH_subtype	COSMIC cancer mutations	central_nervous_system-cerebellum-primitive_neuroectodermal_tumour-medulloblastoma-SHH_subtype	653	12	16828	49	NTRK2,PTPRZ1,CTNND2,MAML2,PARD3B,NEBL,ITPR2,RYR3,CPE,ABLIM1,NPAS3,PRKG1
2.646e-07	-15.15	SHH_subtype	COSMIC cancer mutations	SHH_subtype	654	12	16828	49	PTPRZ1,ITPR2,NTRK2,CPE,RYR3,CTNND2,NPAS3,ABLIM1,NEBL,PRKG1,PARD3B,MAML2
2.811e-07	-15.08	generation of neurons	biological process	GO:0048699	1158	15	18204	50	BMPR1B,CTNND2,PTPRZ1,TNIK,CTNNA2,SOX5,PREX2,PRKG1,RORA,SLC1A3,NTM,FUT9,NTRK2,NFIA,GPM6A
2.862e-07	-15.07	neurogenesis	biological process	GO:0022008	1334	16	18204	50	NFIA,GPM6A,NTRK2,QKI,NTM,RORA,SLC1A3,FUT9,PREX2,PRKG1,SOX5,TNIK,CTNNA2,BMPR1B,PTPRZ1,CTNND2
5.321e-07	-14.45	MAPT (microtubule associated protein tau)	protein interactions	4137	948	13	19454	50	LSAMP,PPP2R2B,CTNND2,NEBL,NTM,TNIK,SLC1A3,GPM6A,CTNNA2,SORBS1,ATP1A2,ABLIM1,SLC1A2
6.811e-07	-14.20	myelodysplastic_syndrome	COSMIC cancer mutations	myelodysplastic_syndrome	1174	15	16828	49	RYR3,SLC1A2,ATP1A2,TNIK,BMPR1B,NFIA,PRKG1,PREX2,NPAS3,ADCY2,FBXL7,LSAMP,NTRK2,NKAIN3,SOX5
6.811e-07	-14.20	haematopoietic_and_lymphoid_tissue-haematopoietic_neoplasm-myelodysplastic_syndrome	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue-haematopoietic_neoplasm-myelodysplastic_syndrome	1174	15	16828	49	ATP1A2,SLC1A2,RYR3,PRKG1,NFIA,BMPR1B,TNIK,ADCY2,FBXL7,NPAS3,PREX2,LSAMP,NKAIN3,NTRK2,SOX5
7.801e-07	-14.06	neuron differentiation	biological process	GO:0030182	1081	14	18204	50	PTPRZ1,CTNND2,BMPR1B,CTNNA2,TNIK,NTRK2,NFIA,GPM6A,PRKG1,PREX2,FUT9,RORA,SLC1A3,NTM
1.129e-06	-13.69	system development	biological process	GO:0048731	3533	25	18204	50	NTRK2,GPM6A,NFIA,RORA,FUT9,PRKG1,SOX5,SLC1A2,BMPR1B,CTNND2,PTPRZ1,RFX4,LSAMP,MSI2,QKI,SLC1A3,NTM,PREX2,ATP1A2,TRPS1,CSGALNACT1,TNIK,CPE,CTNNA2,NEBL
1.160e-06	-13.67	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm	7307	38	16828	49	RYR3,SLC1A3,SPARCL1,QKI,BMPR1B,NHSL1,GPM6A,PPP2R2B,RFX4,LSAMP,MGAT4C,CDH20,MAML2,TPD52L1,ITPR2,SLC1A2,CPE,RORA,PREX2,ABLIM1,MACF1,ADCY2,FBXL7,TNIK,PRKG1,SASH1,NTRK2,PTPRZ1,NKAIN3,CTNND2,GLIS3,GPC5,SOX5,SFXN5,FMN2,CSGALNACT1,PARD3B,NEBL
1.377e-06	-13.50	haematopoietic_and_lymphoid_tissue-haematopoietic_neoplasm	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue-haematopoietic_neoplasm	764	12	16828	49	RYR3,SLC1A2,ATP1A2,PREX2,FBXL7,ADCY2,NTRK2,NKAIN3,GPC5,LSAMP,SOX5,MAML2
1.990e-06	-13.13	cell morphogenesis	biological process	GO:0000902	687	11	18204	50	NFIA,GPM6A,CDH20,SLC1A3,TNIK,CTNNA2,BMPR1B,PREX2,CTNND2,PTPRZ1,PRKG1
2.521e-06	-12.89	multicellular organism development	biological process	GO:0007275	3957	26	18204	50	NTRK2,GPM6A,NFIA,FUT9,RORA,PRKG1,SOX5,SLC1A2,PTPRZ1,CTNND2,BMPR1B,RFX4,LSAMP,CDH20,QKI,MSI2,SLC1A3,NTM,ATP1A2,PREX2,TRPS1,CSGALNACT1,CTNNA2,CPE,TNIK,NEBL
2.948e-06	-12.73	anatomical structure morphogenesis	biological process	GO:0009653	2225	19	18204	50	BMPR1B,PTPRZ1,CTNND2,NEBL,TNIK,CPE,CTNNA2,ABLIM1,CSGALNACT1,SOX5,PREX2,PRKG1,SLC1A3,RORA,QKI,NFIA,GPM6A,NTRK2,CDH20
3.019e-06	-12.71	soft_tissue	COSMIC cancer mutations	soft_tissue	5828	33	16828	49	TRPS1,LSAMP,CDH20,MAML2,TPD52L1,SORBS1,RYR3,SLC1A3,SPARCL1,NFIA,NHSL1,PPP2R2B,GPM6A,NTRK2,SASH1,PTPRZ1,NKAIN3,CTNND2,GLIS3,GPC5,SOX5,FMN2,NEBL,PARD3B,ITPR2,SLC1A2,RORA,PREX2,MACF1,FBXL7,NPAS3,ADCY2,PRKG1
3.116e-06	-12.68	lymph_node	COSMIC cancer mutations	lymph_node	1703	17	16828	49	TNIK,GPM6A,PRKG1,ITPR2,RYR3,SLC1A3,SOX5,SFXN5,MAML2,NEBL,PARD3B,NTRK2,DTNA,TRPS1,CTNND2,LSAMP,GPC5
6.186e-06	-11.99	cervix-carcinoma-squamous_cell_carcinoma	COSMIC cancer mutations	cervix-carcinoma-squamous_cell_carcinoma	11789	47	16828	49	TNIK,PRKG1,RORA,MACF1,ZBTB20,CPE,ATP1A2,CSGALNACT1,NEBL,CTNND2,NTM,SASH1,NTRK2,PTPRZ1,DTNA,NFIA,BMPR1B,GPM6A,QKI,SLC1A3,MAML2,TPD52L1,MGAT4C,FUT9,LSAMP,TRPS1,ABLIM1,PREX2,NPAS3,FBXL7,ADCY2,SLC1A2,ITPR2,FMN2,SFXN5,PARD3B,SOX5,GLIS3,GPC5,NHSL1,PPP2R2B,RYR3,SPARCL1,SORBS1,CDH20,PITPNC1,RFX4
6.238e-06	-11.98	Salivary secretion	KEGG pathways	hsa04970	90	5	7161	22	PRKG1,ATP1A2,RYR3,ITPR2,ADCY2
6.238e-06	-11.98	Salivary secretion	KEGG pathways	ko04970	90	5	7161	22	ATP1A2,PRKG1,ADCY2,RYR3,ITPR2
6.276e-06	-11.98	cervix	COSMIC cancer mutations	cervix	11793	47	16828	49	MAML2,TPD52L1,FUT9,MGAT4C,LSAMP,TRPS1,NFIA,BMPR1B,GPM6A,QKI,SLC1A3,CSGALNACT1,NEBL,CTNND2,SASH1,NTM,NTRK2,PTPRZ1,DTNA,TNIK,PRKG1,RORA,MACF1,ZBTB20,CPE,ATP1A2,CDH20,PITPNC1,RFX4,NHSL1,PPP2R2B,RYR3,SPARCL1,SORBS1,SFXN5,FMN2,PARD3B,SOX5,GLIS3,GPC5,PREX2,ABLIM1,FBXL7,ADCY2,NPAS3,SLC1A2,ITPR2
7.388e-06	-11.82	pharynx	COSMIC cancer mutations	pharynx	2696	21	16828	49	CTNND2,GPC5,NTRK2,DTNA,RFX4,PTPRZ1,FMN2,SFXN5,PARD3B,FUT9,PITPNC1,RYR3,ATP1A2,SLC1A2,SORBS1,NHSL1,NFIA,MACF1,PREX2,QKI,NPAS3
8.905e-06	-11.63	mouth	COSMIC cancer mutations	mouth	9004	41	16828	49	MAML2,PITPNC1,CDH20,FUT9,MGAT4C,LSAMP,RFX4,TRPS1,PPP2R2B,GPM6A,NHSL1,QKI,SLC1A3,RYR3,SORBS1,PARD3B,NEBL,FMN2,CSGALNACT1,SFXN5,SOX5,GPC5,CTNND2,DTNA,PTPRZ1,SASH1,NTM,NTRK2,PRKG1,TNIK,FBXL7,ADCY2,NPAS3,ZBTB20,MACF1,ABLIM1,PREX2,RORA,ATP1A2,SLC1A2,ITPR2
9.076e-06	-11.61	autonomic_ganglia	COSMIC cancer mutations	autonomic_ganglia	4005	26	16828	49	RYR3,GPM6A,NHSL1,NFIA,RFX4,TRPS1,MAML2,PITPNC1,FUT9,ATP1A2,SLC1A2,PRKG1,TNIK,NPAS3,ADCY2,FBXL7,MACF1,PREX2,GLIS3,CTNND2,PTPRZ1,NTRK2,SASH1,PARD3B,NEBL,FMN2
1.097e-05	-11.42	chronic_lymphocytic_leukaemia-small_lymphocytic_lymphoma	COSMIC cancer mutations	chronic_lymphocytic_leukaemia-small_lymphocytic_lymphoma	3511	24	16828	49	PPP2R2B,BMPR1B,SLC1A3,RYR3,PITPNC1,MGAT4C,FUT9,LSAMP,PRKG1,TNIK,MSI2,NPAS3,ADCY2,FBXL7,PREX2,MACF1,CPE,PARD3B,FMN2,GPC5,CTNND2,DTNA,PTPRZ1,NTRK2
1.097e-05	-11.42	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-chronic_lymphocytic_leukaemia-small_lymphocytic_lymphoma	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-chronic_lymphocytic_leukaemia-small_lymphocytic_lymphoma	3511	24	16828	49	CTNND2,GPC5,NTRK2,PTPRZ1,DTNA,FMN2,PARD3B,CPE,MSI2,TNIK,PRKG1,MACF1,PREX2,FBXL7,ADCY2,NPAS3,LSAMP,MGAT4C,FUT9,PITPNC1,RYR3,SLC1A3,BMPR1B,PPP2R2B
1.311e-05	-11.24	anatomical structure development	biological process	GO:0048856	5207	29	18204	50	QKI,MSI2,RFX4,LSAMP,CDH20,ATP1A2,FMN2,PREX2,SLC1A3,NTM,TRPS1,CSGALNACT1,SPARCL1,NEBL,CTNNA2,CPE,TNIK,NTRK2,NFIA,GPM6A,PRKG1,FUT9,RORA,ABLIM1,SLC1A2,SOX5,CTNND2,PTPRZ1,BMPR1B
1.668e-05	-11.00	neuron development	biological process	GO:0048666	859	11	18204	50	PTPRZ1,CTNND2,BMPR1B,CTNNA2,TNIK,GPM6A,NTRK2,PRKG1,PREX2,NTM,SLC1A3
2.188e-05	-10.73	tibia	COSMIC cancer mutations	tibia	836	11	16828	49	GPM6A,PRKG1,TNIK,ABLIM1,PREX2,MACF1,QKI,LSAMP,CPE,CTNND2,NKAIN3
2.586e-05	-10.56	carcinoid-endocrine_tumour	COSMIC cancer mutations	carcinoid-endocrine_tumour	7752	37	16828	49	SASH1,NTRK2,NKAIN3,PTPRZ1,CTNND2,GLIS3,GPC5,SOX5,SFXN5,CSGALNACT1,FMN2,NEBL,ITPR2,SLC1A2,ATP1A2,CPE,MACF1,ABLIM1,PREX2,RORA,ADCY2,FBXL7,TNIK,PRKG1,RFX4,TRPS1,LSAMP,CDH20,TPD52L1,MAML2,RYR3,SLC1A3,QKI,NHSL1,BMPR1B,GPM6A,PPP2R2B
2.773e-05	-10.49	developmental process	biological process	GO:0032502	5716	30	18204	50	PTPRZ1,CTNND2,BMPR1B,NHSL1,SOX5,ABLIM1,SLC1A2,FUT9,RORA,PRKG1,NTRK2,GPM6A,NFIA,CPE,CTNNA2,TNIK,SPARCL1,NEBL,TRPS1,CSGALNACT1,SLC1A3,NTM,ATP1A2,PREX2,FMN2,RFX4,LSAMP,CDH20,QKI,MSI2
2.776e-05	-10.49	autonomic_ganglia-neuroblastoma	COSMIC cancer mutations	autonomic_ganglia-neuroblastoma	3970	25	16828	49	PTPRZ1,NTRK2,SASH1,GLIS3,CTNND2,NEBL,PARD3B,FMN2,ATP1A2,SLC1A2,NPAS3,FBXL7,ADCY2,MACF1,PREX2,PRKG1,TNIK,RFX4,TRPS1,PITPNC1,FUT9,MAML2,RYR3,GPM6A,NFIA
2.789e-05	-10.49	neuroblastoma	COSMIC cancer mutations	neuroblastoma	3971	25	16828	49	TRPS1,RFX4,MAML2,FUT9,PITPNC1,RYR3,NFIA,GPM6A,GLIS3,CTNND2,NTRK2,SASH1,PTPRZ1,FMN2,PARD3B,NEBL,ATP1A2,SLC1A2,TNIK,PRKG1,MACF1,PREX2,NPAS3,FBXL7,ADCY2
3.676e-05	-10.21	Astrocytic Glutamate-Glutamine Uptake And Metabolism	REACTOME pathways	R-HSA-210455	4	2	10285	26	SLC1A3,SLC1A2
3.676e-05	-10.21	Neurotransmitter uptake and Metabolism In Glial Cells	REACTOME pathways	R-HSA-112313	4	2	10285	26	SLC1A2,SLC1A3
4.606e-05	-9.99	plasma_cell_myeloma	COSMIC cancer mutations	plasma_cell_myeloma	1263	13	16828	49	CTNND2,TRPS1,NTM,NTRK2,NEBL,FMN2,FUT9,RYR3,GPM6A,TNIK,ADCY2,ABLIM1,MACF1
4.606e-05	-9.99	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-plasma_cell_myeloma	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-plasma_cell_myeloma	1263	13	16828	49	NEBL,FMN2,FUT9,CTNND2,TRPS1,NTRK2,NTM,GPM6A,TNIK,ADCY2,MACF1,ABLIM1,RYR3
4.623e-05	-9.98	SFN (stratifin)	protein interactions	2810	671	9	19454	50	ABLIM1,MACF1,TNIK,PARD3B,SORBS1,NFIA,SASH1,FMN2,PPP2R2B
4.882e-05	-9.93	neuron projection morphogenesis	biological process	GO:0048812	486	8	18204	50	GPM6A,TNIK,CTNNA2,BMPR1B,PREX2,CTNND2,PTPRZ1,PRKG1
4.896e-05	-9.92	prostate-carcinoma-adenocarcinoma	COSMIC cancer mutations	prostate-carcinoma-adenocarcinoma	12379	47	16828	49	SLC1A3,QKI,BMPR1B,NFIA,GPM6A,TRPS1,LSAMP,FUT9,MGAT4C,TPD52L1,MAML2,ATP1A2,CPE,MACF1,RORA,ZBTB20,TNIK,PRKG1,NTRK2,NTM,SASH1,NKAIN3,PTPRZ1,CTNND2,CSGALNACT1,NEBL,SORBS1,RYR3,SPARCL1,NHSL1,PPP2R2B,RFX4,CDH20,PITPNC1,ITPR2,SLC1A2,ABLIM1,PREX2,FBXL7,NPAS3,ADCY2,GLIS3,GPC5,SOX5,SFXN5,FMN2,PARD3B
5.135e-05	-9.88	lung-right_upper_lobe-carcinoma-adenocarcinoma	COSMIC cancer mutations	lung-right_upper_lobe-carcinoma-adenocarcinoma	10376	43	16828	49	GPC5,CTNND2,GLIS3,PTPRZ1,DTNA,NKAIN3,SASH1,NTM,NTRK2,NEBL,PARD3B,FMN2,CSGALNACT1,SFXN5,SOX5,CPE,SLC1A2,ATP1A2,ITPR2,PRKG1,TNIK,ZBTB20,ADCY2,NPAS3,FBXL7,RORA,ABLIM1,MACF1,PREX2,LSAMP,TRPS1,RFX4,PITPNC1,FUT9,MGAT4C,CDH20,SLC1A3,RYR3,SORBS1,GPM6A,PPP2R2B,NFIA,BMPR1B
5.135e-05	-9.88	right_upper_lobe	COSMIC cancer mutations	right_upper_lobe	10376	43	16828	49	RFX4,PITPNC1,CDH20,SORBS1,RYR3,PPP2R2B,GPC5,GLIS3,SOX5,PARD3B,FMN2,SFXN5,ITPR2,SLC1A2,NPAS3,ADCY2,FBXL7,PREX2,ABLIM1,TRPS1,LSAMP,FUT9,MGAT4C,SLC1A3,GPM6A,BMPR1B,NFIA,NKAIN3,DTNA,PTPRZ1,NTM,NTRK2,SASH1,CTNND2,NEBL,CSGALNACT1,CPE,ATP1A2,ZBTB20,MACF1,RORA,PRKG1,TNIK
5.246e-05	-9.86	plasma membrane bounded cell projection morphogenesis	biological process	GO:0120039	491	8	18204	50	GPM6A,TNIK,CTNNA2,BMPR1B,PREX2,PTPRZ1,CTNND2,PRKG1
5.634e-05	-9.78	cell projection morphogenesis	biological process	GO:0048858	496	8	18204	50	GPM6A,CTNNA2,TNIK,PRKG1,CTNND2,PTPRZ1,PREX2,BMPR1B
5.783e-05	-9.76	skin-trunk-malignant_melanoma-nodular	COSMIC cancer mutations	skin-trunk-malignant_melanoma-nodular	1291	13	16828	49	CPE,ATP1A2,SPARCL1,PREX2,ABLIM1,MACF1,NPAS3,CTNND2,GLIS3,NTRK2,PTPRZ1,NEBL,CDH20
6.287e-05	-9.67	haematopoietic_and_lymphoid_tissue-lymph_node-lymphoid_neoplasm-mantle_cell_lymphoma	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue-lymph_node-lymphoid_neoplasm-mantle_cell_lymphoma	476	8	16828	49	LSAMP,GPC5,RYR3,CTNND2,GPM6A,PRKG1,SFXN5,MAML2
6.432e-05	-9.65	central nervous system development	biological process	GO:0007417	995	11	18204	50	NTRK2,RFX4,QKI,MSI2,SLC1A2,RORA,CTNNA2,BMPR1B,ATP1A2,PRKG1,PTPRZ1
6.856e-05	-9.59	glutamate:sodium symporter activity	molecular function	GO:0015501	5	2	18094	48	SLC1A3,SLC1A2
6.856e-05	-9.59	high-affinity L-glutamate transmembrane transporter activity	molecular function	GO:0005314	5	2	18094	48	SLC1A3,SLC1A2
7.145e-05	-9.55	nodular	COSMIC cancer mutations	nodular	1515	14	16828	49	CPE,ATP1A2,SPARCL1,ABLIM1,PREX2,MACF1,NPAS3,NTRK2,PTPRZ1,CTNND2,GLIS3,CDH20,FMN2,NEBL
7.355e-05	-9.52	D-aspartate import across plasma membrane	biological process	GO:0070779	5	2	18204	50	SLC1A2,SLC1A3
7.355e-05	-9.52	D-aspartate transmembrane transport	biological process	GO:0070777	5	2	18204	50	SLC1A3,SLC1A2
7.513e-05	-9.50	neurotransmitter uptake	biological process	GO:0001504	30	3	18204	50	ATP1A2,SLC1A2,SLC1A3
7.654e-05	-9.48	upper_aerodigestive_tract-larynx-carcinoma-squamous_cell_carcinoma	COSMIC cancer mutations	upper_aerodigestive_tract-larynx-carcinoma-squamous_cell_carcinoma	1946	16	16828	49	NEBL,PARD3B,FMN2,MAML2,CSGALNACT1,SOX5,MGAT4C,RYR3,ITPR2,GPM6A,TNIK,BMPR1B,NPAS3,ZBTB20,MACF1,RORA
7.750e-05	-9.47	larynx	COSMIC cancer mutations	larynx	1948	16	16828	49	ITPR2,RYR3,NPAS3,ZBTB20,MACF1,RORA,GPM6A,TNIK,BMPR1B,SOX5,MGAT4C,NEBL,PARD3B,MAML2,CSGALNACT1,FMN2
7.937e-05	-9.44	prostate	COSMIC cancer mutations	prostate	13883	49	16828	49	CSGALNACT1,NEBL,NTM,NTRK2,SASH1,DTNA,NKAIN3,PTPRZ1,CTNND2,MACF1,RORA,ZBTB20,TNIK,PRKG1,ATP1A2,CPE,FUT9,MGAT4C,TPD52L1,MAML2,TRPS1,LSAMP,QKI,BMPR1B,NFIA,GPM6A,SLC1A3,SOX5,FMN2,SFXN5,PARD3B,GLIS3,GPC5,ABLIM1,PREX2,ADCY2,FBXL7,NPAS3,MSI2,ITPR2,SLC1A2,CDH20,PITPNC1,RFX4,NHSL1,PPP2R2B,SORBS1,RYR3,SPARCL1
8.255e-05	-9.40	NTM (neurotrimin)	protein interactions	50863	33	3	19454	50	NTM,GPM6A,LSAMP
8.305e-05	-9.40	cell junction	cellular component	GO:0030054	2224	16	19108	49	SLC1A2,QKI,PTPRZ1,NTRK2,CTNND2,NFIA,PARD3B,DTNA,SORBS1,GPM6A,ATP1A2,CDH20,SLC1A3,TNIK,SPARCL1,CTNNA2
1.012e-04	-9.20	oesophagus-carcinoma	COSMIC cancer mutations	oesophagus-carcinoma	4269	25	16828	49	ITPR2,MACF1,PREX2,ZBTB20,FBXL7,ADCY2,TNIK,PRKG1,NTRK2,NTM,PTPRZ1,CTNND2,SOX5,FMN2,CSGALNACT1,PARD3B,SORBS1,RYR3,NFIA,NHSL1,GPM6A,PPP2R2B,TRPS1,RFX4,CDH20
1.023e-04	-9.19	bone	COSMIC cancer mutations	bone	8157	37	16828	49	TPD52L1,MAML2,TRPS1,LSAMP,QKI,GPM6A,PPP2R2B,SORBS1,RYR3,SPARCL1,SLC1A3,SOX5,CSGALNACT1,FMN2,SFXN5,NEBL,PARD3B,SASH1,NTRK2,DTNA,NKAIN3,PTPRZ1,GLIS3,CTNND2,GPC5,PREX2,MACF1,ABLIM1,RORA,NPAS3,ADCY2,ZBTB20,TNIK,PRKG1,ITPR2,ATP1A2,CPE
1.064e-04	-9.15	RIH_dom	interpro domains	IPR000699	6	2	18521	50	RYR3,ITPR2
1.064e-04	-9.15	RyR/IP3R_RIH_dom_sf	interpro domains	IPR035910	6	2	18521	50	ITPR2,RYR3
1.064e-04	-9.15	Ins145_P3_rcpt	interpro domains	IPR014821	6	2	18521	50	RYR3,ITPR2
1.064e-04	-9.15	Ryanodine_IP3_receptor	interpro domains	IPR015925	6	2	18521	50	ITPR2,RYR3
1.064e-04	-9.15	RIH_assoc-dom	interpro domains	IPR013662	6	2	18521	50	RYR3,ITPR2
1.077e-04	-9.14	upper_aerodigestive_tract-mouth-carcinoma	COSMIC cancer mutations	upper_aerodigestive_tract-mouth-carcinoma	6426	32	16828	49	RFX4,TRPS1,PITPNC1,CDH20,MGAT4C,FUT9,MAML2,SORBS1,SLC1A3,RYR3,QKI,GPM6A,PPP2R2B,NHSL1,NTM,SASH1,GPC5,CTNND2,SOX5,PARD3B,FMN2,SFXN5,SLC1A2,FBXL7,NPAS3,ADCY2,ZBTB20,MACF1,ABLIM1,PREX2,RORA,PRKG1
1.101e-04	-9.11	D-amino acid transport	biological process	GO:0042940	6	2	18204	50	SLC1A2,SLC1A3
1.101e-04	-9.11	L-aspartate import across plasma membrane	biological process	GO:0140009	6	2	18204	50	SLC1A3,SLC1A2
1.106e-04	-9.11	RIH_assoc	pfam domains	PF08454	6	2	17795	49	ITPR2,RYR3
1.106e-04	-9.11	RYDR_ITPR	pfam domains	PF01365	6	2	17795	49	ITPR2,RYR3
1.106e-04	-9.11	Ins145_P3_rec	pfam domains	PF08709	6	2	17795	49	RYR3,ITPR2
1.167e-04	-9.06	IP3 receptor type 1 binding core, RIH domain	gene3d domains	1.25.10.30	6	2	14470	41	ITPR2,RYR3
1.173e-04	-9.05	adherens junction	cellular component	GO:0005912	188	5	19108	49	CTNNA2,PARD3B,CDH20,SORBS1,CTNND2
1.323e-04	-8.93	oesophagus-carcinoma-squamous_cell_carcinoma	COSMIC cancer mutations	oesophagus-carcinoma-squamous_cell_carcinoma	6486	32	16828	49	CPE,ATP1A2,ITPR2,PRKG1,TNIK,ZBTB20,FBXL7,ADCY2,NPAS3,ABLIM1,MACF1,PREX2,GPC5,CTNND2,GLIS3,PTPRZ1,SASH1,PARD3B,NEBL,SFXN5,FMN2,CSGALNACT1,SOX5,SPARCL1,RYR3,SORBS1,GPM6A,BMPR1B,TRPS1,MAML2,PITPNC1,MGAT4C
1.487e-04	-8.81	Na-dicarboxylate_symporter	interpro domains	IPR001991	7	2	18521	50	SLC1A3,SLC1A2
1.487e-04	-8.81	Na-dicarboxylate_symporter_CS	interpro domains	IPR018107	7	2	18521	50	SLC1A2,SLC1A3
1.487e-04	-8.81	Na:dicarbo_symporter_sf	interpro domains	IPR036458	7	2	18521	50	SLC1A3,SLC1A2
1.546e-04	-8.77	SDF	pfam domains	PF00375	7	2	17795	49	SLC1A2,SLC1A3
1.603e-04	-8.74	trunk	COSMIC cancer mutations	trunk	3554	22	16828	49	RYR3,SPARCL1,SLC1A3,ATP1A2,CPE,PPP2R2B,PREX2,MACF1,ABLIM1,NPAS3,GLIS3,CTNND2,LSAMP,NTRK2,SASH1,PTPRZ1,TRPS1,MAML2,NEBL,SOX5,CDH20,MGAT4C
1.630e-04	-8.72	Sodium:dicarboxylate symporter	gene3d domains	1.10.3860.10	7	2	14470	41	SLC1A2,SLC1A3
1.662e-04	-8.70	cellular response to alkaloid	biological process	GO:0071312	39	3	18204	50	SLC1A3,SLC1A2,RYR3
1.762e-04	-8.64	pancreas-carcinoid-endocrine_tumour	COSMIC cancer mutations	pancreas-carcinoid-endocrine_tumour	7250	34	16828	49	NHSL1,BMPR1B,PPP2R2B,GPM6A,QKI,RYR3,SLC1A3,TPD52L1,MAML2,CDH20,LSAMP,RFX4,PRKG1,ABLIM1,MACF1,PREX2,RORA,FBXL7,ADCY2,ATP1A2,CPE,SLC1A2,ITPR2,FMN2,CSGALNACT1,SFXN5,NEBL,SOX5,GLIS3,CTNND2,GPC5,SASH1,NTRK2,NKAIN3
1.841e-04	-8.60	beta-catenin binding	molecular function	GO:0008013	107	4	18094	48	RORA,CDH20,CTNND2,CTNNA2
1.874e-04	-8.58	bone-tibia-other-chondroblastoma	COSMIC cancer mutations	bone-tibia-other-chondroblastoma	98	4	16828	49	NKAIN3,LSAMP,GPM6A,CTNND2
1.949e-04	-8.54	cell morphogenesis involved in neuron differentiation	biological process	GO:0048667	443	7	18204	50	BMPR1B,PREX2,PTPRZ1,CTNND2,PRKG1,SLC1A3,CTNNA2
2.008e-04	-8.51	scalp	COSMIC cancer mutations	scalp	2110	16	16828	49	SORBS1,ATP1A2,PREX2,MACF1,RORA,PPP2R2B,PRKG1,NFIA,PTPRZ1,TRPS1,NTM,LSAMP,GPC5,SOX5,NEBL,FMN2
2.059e-04	-8.49	cell development	biological process	GO:0048468	2236	16	18204	50	PREX2,FMN2,PRKG1,NTM,RORA,SLC1A3,MSI2,QKI,GPM6A,NTRK2,BMPR1B,PTPRZ1,CTNND2,NEBL,TNIK,CTNNA2
2.183e-04	-8.43	NA_DICARBOXYL_SYMP_1	prosite domains	PS00713	7	2	12186	40	SLC1A2,SLC1A3
2.183e-04	-8.43	NA_DICARBOXYL_SYMP_2	prosite domains	PS00714	7	2	12186	40	SLC1A2,SLC1A3
2.304e-04	-8.38	NEGR1 (neuronal growth regulator 1)	protein interactions	257194	9	2	19454	50	NTM,LSAMP
2.304e-04	-8.38	LSAMP (limbic system associated membrane protein)	protein interactions	4045	9	2	19454	50	LSAMP,NTM
2.383e-04	-8.34	lung-right_lower_lobe-carcinoma-adenocarcinoma	COSMIC cancer mutations	lung-right_lower_lobe-carcinoma-adenocarcinoma	5692	29	16828	49	SORBS1,RYR3,SLC1A3,GPM6A,PPP2R2B,TRPS1,LSAMP,MGAT4C,FUT9,CDH20,MAML2,ITPR2,ATP1A2,MACF1,NPAS3,ADCY2,FBXL7,PRKG1,NTM,NTRK2,PTPRZ1,NKAIN3,DTNA,CTNND2,GPC5,SOX5,FMN2,PARD3B,NEBL
2.383e-04	-8.34	right_lower_lobe	COSMIC cancer mutations	right_lower_lobe	5692	29	16828	49	GPC5,CTNND2,PTPRZ1,NKAIN3,DTNA,NTM,NTRK2,NEBL,PARD3B,FMN2,SOX5,ATP1A2,ITPR2,PRKG1,ADCY2,NPAS3,FBXL7,MACF1,LSAMP,TRPS1,MAML2,MGAT4C,FUT9,CDH20,SLC1A3,RYR3,SORBS1,PPP2R2B,GPM6A
2.551e-04	-8.27	acidic amino acid transport	biological process	GO:0015800	45	3	18204	50	NTRK2,SLC1A3,SLC1A2
2.586e-04	-8.26	cellular response to organic cyclic compound	biological process	GO:0071407	464	7	18204	50	SLC1A3,RORA,ITPR2,RYR3,ATP1A2,ADCY2,SLC1A2
2.601e-04	-8.25	dendrite development	biological process	GO:0016358	113	4	18204	50	PREX2,PRKG1,CTNND2,CTNNA2
2.680e-04	-8.22	haematopoietic_and_lymphoid_tissue-lymph_node-lymphoid_neoplasm-diffuse_large_B_cell_lymphoma	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue-lymph_node-lymphoid_neoplasm-diffuse_large_B_cell_lymphoma	748	9	16828	49	NEBL,PRKG1,SOX5,SLC1A3,CTNND2,TRPS1,DTNA,ITPR2,NTRK2
2.888e-04	-8.15	EDTRNSPORT	prints domains	PR00173	7	2	5227	20	SLC1A3,SLC1A2
3.170e-04	-8.06	MIR_motif	interpro domains	IPR016093	10	2	18521	50	RYR3,ITPR2
3.170e-04	-8.06	MIR_dom_sf	interpro domains	IPR036300	10	2	18521	50	RYR3,ITPR2
3.281e-04	-8.02	neuronal action potential propagation	biological process	GO:0019227	10	2	18204	50	NTRK2,ATP1A2
3.281e-04	-8.02	action potential propagation	biological process	GO:0098870	10	2	18204	50	NTRK2,ATP1A2
3.281e-04	-8.02	cellular response to cocaine	biological process	GO:0071314	10	2	18204	50	SLC1A3,SLC1A2
3.296e-04	-8.02	MIR	pfam domains	PF02815	10	2	17795	49	ITPR2,RYR3
3.346e-04	-8.00	central_nervous_system-brainstem-glioma-oligoastrocytoma_Grade_III	COSMIC cancer mutations	central_nervous_system-brainstem-glioma-oligoastrocytoma_Grade_III	114	4	16828	49	SOX5,PREX2,SLC1A2,RYR3
3.409e-04	-7.98	plasma membrane	cellular component	GO:0005886	5538	26	19108	49	ATP1A2,ITPR2,SORBS1,CPE,CDH20,CTNNA2,MACF1,TNIK,GPC5,SLC1A3,SLC1A2,ADCY2,RYR3,PARD3B,PRKG1,PREX2,DTNA,GPM6A,BMPR1B,FMN2,PTPRZ1,NKAIN3,NTRK2,LSAMP,CTNND2,NTM
3.508e-04	-7.96	IRAG1 (inositol 1,4,5-triphosphate receptor associated 1)	protein interactions	10335	11	2	19454	50	ITPR2,PRKG1
3.571e-04	-7.94	Glutamatergic synapse	KEGG pathways	hsa04724	114	4	7161	22	ADCY2,ITPR2,SLC1A3,SLC1A2
3.571e-04	-7.94	Glutamatergic synapse	KEGG pathways	ko04724	114	4	7161	22	SLC1A3,ADCY2,ITPR2,SLC1A2
3.638e-04	-7.92	Ion homeostasis	REACTOME pathways	R-HSA-5578775	56	3	10285	26	ITPR2,ATP1A2,RYR3
4.003e-04	-7.82	L-aspartate transmembrane transport	biological process	GO:0070778	11	2	18204	50	SLC1A2,SLC1A3
4.003e-04	-7.82	L-glutamate import across plasma membrane	biological process	GO:0098712	11	2	18204	50	SLC1A3,SLC1A2
4.096e-04	-7.80	multicellular organismal process	biological process	GO:0032501	6177	29	18204	50	NEBL,CTNNA2,CPE,TNIK,TRPS1,CSGALNACT1,ATP1A2,PREX2,SLC1A3,NTM,MSI2,QKI,RFX4,CDH20,LSAMP,CTNND2,PTPRZ1,BMPR1B,DTNA,ABLIM1,SLC1A2,SOX5,PRKG1,RYR3,FUT9,RORA,NTRK2,GPM6A,NFIA
4.146e-04	-7.79	regulation of chondrocyte differentiation	biological process	GO:0032330	53	3	18204	50	SOX5,TRPS1,BMPR1B
4.203e-04	-7.77	OAS2 (2'-5'-oligoadenylate synthetase 2)	protein interactions	4939	12	2	19454	50	PRKG1,SASH1
4.282e-04	-7.76	haematopoietic_and_lymphoid_tissue	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue	14368	49	16828	49	CPE,ATP1A2,PRKG1,TNIK,ZBTB20,MACF1,RORA,CTNND2,DTNA,NKAIN3,PTPRZ1,NTM,SASH1,NTRK2,NEBL,CSGALNACT1,SLC1A3,GPM6A,BMPR1B,NFIA,QKI,LSAMP,TRPS1,TPD52L1,MAML2,FUT9,MGAT4C,SLC1A2,ITPR2,MSI2,NPAS3,ADCY2,FBXL7,ABLIM1,PREX2,GPC5,GLIS3,PARD3B,SFXN5,FMN2,SOX5,SPARCL1,RYR3,SORBS1,PPP2R2B,NHSL1,RFX4,PITPNC1,CDH20
4.439e-04	-7.72	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-follicular_lymphoma	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-follicular_lymphoma	981	10	16828	49	PRKG1,ADCY2,RORA,SOX5,GPC5,LSAMP,CTNND2,NKAIN3,SASH1,ITPR2
4.467e-04	-7.71	skin-scalp-malignant_melanoma	COSMIC cancer mutations	skin-scalp-malignant_melanoma	634	8	16828	49	PREX2,NEBL,PPP2R2B,FMN2,NFIA,SORBS1,PTPRZ1,NTM
4.650e-04	-7.67	MIR	prosite domains	PS50919	10	2	12186	40	ITPR2,RYR3
4.673e-04	-7.67	skin-face-carcinoma-squamous_cell_carcinoma	COSMIC cancer mutations	skin-face-carcinoma-squamous_cell_carcinoma	2036	15	16828	49	NEBL,CSGALNACT1,FMN2,TRPS1,PTPRZ1,GPC5,LSAMP,RORA,PREX2,ABLIM1,MACF1,PPP2R2B,GPM6A,MSI2,ITPR2
4.698e-04	-7.66	amino acid transport	biological process	GO:0006865	132	4	18204	50	SLC1A2,SLC1A3,NTRK2,SFXN5
4.778e-04	-7.65	sarcolemma	cellular component	GO:0042383	142	4	19108	49	PRKG1,ATP1A2,DTNA,RYR3
5.195e-04	-7.56	cell periphery	cellular component	GO:0071944	6020	27	19108	49	CDH20,CPE,SLC1A3,MACF1,CTNNA2,GPC5,TNIK,SORBS1,ITPR2,ATP1A2,PARD3B,ADCY2,SLC1A2,RYR3,FMN2,SPARCL1,GPM6A,DTNA,PRKG1,PREX2,BMPR1B,NTM,CTNND2,NKAIN3,PTPRZ1,LSAMP,NTRK2
5.522e-04	-7.50	neuron projection development	biological process	GO:0031175	693	8	18204	50	CTNNA2,TNIK,PRKG1,CTNND2,PTPRZ1,PREX2,BMPR1B,GPM6A
5.545e-04	-7.50	ductolobular_carcinoma	COSMIC cancer mutations	ductolobular_carcinoma	1619	13	16828	49	CPE,SORBS1,MACF1,PREX2,ABLIM1,QKI,RORA,CTNND2,DTNA,PTPRZ1,PARD3B,FMN2,CDH20
5.545e-04	-7.50	breast-carcinoma-ductolobular_carcinoma	COSMIC cancer mutations	breast-carcinoma-ductolobular_carcinoma	1619	13	16828	49	PTPRZ1,DTNA,CTNND2,CDH20,PARD3B,FMN2,SORBS1,CPE,QKI,RORA,ABLIM1,PREX2,MACF1
5.787e-04	-7.45	follicular_lymphoma	COSMIC cancer mutations	follicular_lymphoma	1209	11	16828	49	GPC5,LSAMP,CTNND2,NKAIN3,SASH1,ITPR2,PRKG1,TNIK,ADCY2,RORA,SOX5
6.089e-04	-7.40	lung-carcinoma-small_cell_carcinoma	COSMIC cancer mutations	lung-carcinoma-small_cell_carcinoma	9908	40	16828	49	GPC5,CTNND2,DTNA,NKAIN3,PTPRZ1,NTRK2,NTM,SASH1,NEBL,PARD3B,FMN2,CSGALNACT1,SOX5,CPE,ATP1A2,ITPR2,PRKG1,TNIK,MSI2,FBXL7,NPAS3,MACF1,ABLIM1,PREX2,RORA,RFX4,TRPS1,TPD52L1,MAML2,PITPNC1,CDH20,MGAT4C,SPARCL1,RYR3,SORBS1,PPP2R2B,GPM6A,BMPR1B,NFIA,QKI
6.145e-04	-7.39	L-glutamate transmembrane transporter activity	molecular function	GO:0005313	14	2	18094	48	SLC1A2,SLC1A3
6.176e-04	-7.39	small_cell_carcinoma	COSMIC cancer mutations	small_cell_carcinoma	9913	40	16828	49	SORBS1,SPARCL1,RYR3,QKI,PPP2R2B,GPM6A,NFIA,BMPR1B,TRPS1,RFX4,PITPNC1,MGAT4C,CDH20,MAML2,TPD52L1,ITPR2,ATP1A2,CPE,NPAS3,FBXL7,RORA,ABLIM1,MACF1,PREX2,PRKG1,MSI2,TNIK,PTPRZ1,NKAIN3,DTNA,SASH1,NTRK2,NTM,GPC5,CTNND2,SOX5,PARD3B,NEBL,FMN2,CSGALNACT1
6.228e-04	-7.38	MIR	smart domains	SM00472	10	2	9717	37	ITPR2,RYR3
6.239e-04	-7.38	upper_aerodigestive_tract-pharynx-carcinoma-nasopharyngeal_carcinoma	COSMIC cancer mutations	upper_aerodigestive_tract-pharynx-carcinoma-nasopharyngeal_carcinoma	1425	12	16828	49	FMN2,SFXN5,PITPNC1,CTNND2,NTRK2,RFX4,NFIA,NHSL1,QKI,PREX2,SLC1A2,ATP1A2
6.239e-04	-7.38	nasopharyngeal_carcinoma	COSMIC cancer mutations	nasopharyngeal_carcinoma	1425	12	16828	49	ATP1A2,SLC1A2,NHSL1,NFIA,PREX2,QKI,CTNND2,NTRK2,RFX4,FMN2,SFXN5,PITPNC1
7.220e-04	-7.23	dendrite morphogenesis	biological process	GO:0048813	64	3	18204	50	CTNND2,PREX2,CTNNA2
7.592e-04	-7.18	CNTNAP2 (contactin associated protein 2)	protein interactions	26047	16	2	19454	50	MACF1,CPE
7.916e-04	-7.14	face	COSMIC cancer mutations	face	2139	15	16828	49	TRPS1,PTPRZ1,GPC5,LSAMP,CSGALNACT1,FMN2,NEBL,ITPR2,RORA,MACF1,ABLIM1,PREX2,MSI2,GPM6A,PPP2R2B
8.086e-04	-7.12	human chr3q13.31	chromosome location	human chr3q13.31	22	2	26134	50	LSAMP,ZBTB20
8.440e-04	-7.08	VASP (vasodilator stimulated phosphoprotein)	protein interactions	7408	288	5	19454	50	FMN2,NEBL,PRKG1,SORBS1,NHSL1
8.795e-04	-7.04	retina development in camera-type eye	biological process	GO:0060041	156	4	18204	50	NTRK2,NFIA,GPM6A,BMPR1B
8.890e-04	-7.03	cellular response to endogenous stimulus	biological process	GO:0071495	1135	10	18204	50	SLC1A3,ITPR2,BMPR1B,ATP1A2,RYR3,NTRK2,NFIA,SORBS1,SOX5,SLC1A2
9.311e-04	-6.98	cell differentiation	biological process	GO:0030154	3645	20	18204	50	CTNNA2,TNIK,NEBL,CTNND2,PTPRZ1,BMPR1B,NHSL1,SOX5,FUT9,RORA,SLC1A3,NTM,PRKG1,FMN2,PREX2,NTRK2,GPM6A,NFIA,QKI,MSI2
9.412e-04	-6.97	cellular developmental process	biological process	GO:0048869	3648	20	18204	50	TNIK,CTNNA2,BMPR1B,PTPRZ1,CTNND2,NEBL,SOX5,NHSL1,NTM,RORA,SLC1A3,FUT9,PREX2,FMN2,PRKG1,GPM6A,NFIA,NTRK2,QKI,MSI2
9.623e-04	-6.95	actin binding	molecular function	GO:0003779	434	6	18094	48	MACF1,SORBS1,ABLIM1,NEBL,CTNNA2,FMN2
9.965e-04	-6.91	plasma membrane bounded cell projection organization	biological process	GO:0120036	1152	10	18204	50	TNIK,CTNNA2,PREX2,BMPR1B,PRKG1,PTPRZ1,CTNND2,GPM6A,RFX4,ABLIM1
1.022e-03	-6.89	Htt (huntingtin)	protein interactions	15194	77	3	19454	50	LSAMP,GPM6A,NTM
1.026e-03	-6.88	acidic amino acid transmembrane transporter activity	molecular function	GO:0015172	18	2	18094	48	SLC1A2,SLC1A3
1.026e-03	-6.88	intracellularly gated calcium channel activity	molecular function	GO:0015278	18	2	18094	48	ITPR2,RYR3
1.030e-03	-6.88	FLOT1 (flotillin 1)	protein interactions	10211	453	6	19454	50	MACF1,ABLIM1,SOX5,SORBS1,FMN2,DTNA
1.043e-03	-6.87	synapse	cellular component	GO:0045202	1473	11	19108	49	CTNND2,TNIK,SPARCL1,SLC1A3,PTPRZ1,ATP1A2,DTNA,QKI,SLC1A2,GPM6A,NTRK2
1.057e-03	-6.85	metal ion transmembrane transporter activity	molecular function	GO:0046873	442	6	18094	48	GPM6A,SLC1A3,ITPR2,SLC1A2,RYR3,ATP1A2
1.059e-03	-6.85	regulation of cartilage development	biological process	GO:0061035	73	3	18204	50	BMPR1B,TRPS1,SOX5
1.066e-03	-6.84	lung-left_upper_lobe-carcinoma-adenocarcinoma	COSMIC cancer mutations	lung-left_upper_lobe-carcinoma-adenocarcinoma	556	7	16828	49	TRPS1,NTRK2,CTNND2,RYR3,FBXL7,ADCY2,PRKG1
1.089e-03	-6.82	left_upper_lobe	COSMIC cancer mutations	left_upper_lobe	558	7	16828	49	PRKG1,ADCY2,FBXL7,RYR3,CTNND2,TRPS1,NTRK2
1.100e-03	-6.81	positive regulation of circadian rhythm	biological process	GO:0042753	18	2	18204	50	RORA,PRKG1
1.134e-03	-6.78	spleen	COSMIC cancer mutations	spleen	408	6	16828	49	PARD3B,TNIK,PTPRZ1,SORBS1,ADCY2,NTM
1.158e-03	-6.76	superficial_spreading	COSMIC cancer mutations	superficial_spreading	1110	10	16828	49	SORBS1,NTM,CTNND2,ADCY2,MGAT4C,FUT9,PREX2,MACF1,PRKG1,PPP2R2B
1.165e-03	-6.76	lung-carcinoma-squamous_cell_carcinoma	COSMIC cancer mutations	lung-carcinoma-squamous_cell_carcinoma	14664	49	16828	49	RFX4,PITPNC1,CDH20,SPARCL1,RYR3,SORBS1,PPP2R2B,NHSL1,GPC5,GLIS3,PARD3B,SFXN5,FMN2,SOX5,SLC1A2,ITPR2,MSI2,ADCY2,NPAS3,FBXL7,ABLIM1,PREX2,LSAMP,TRPS1,MAML2,TPD52L1,MGAT4C,FUT9,SLC1A3,GPM6A,NFIA,BMPR1B,QKI,CTNND2,PTPRZ1,DTNA,NKAIN3,SASH1,NTM,NTRK2,NEBL,CSGALNACT1,ATP1A2,CPE,PRKG1,TNIK,ZBTB20,RORA,MACF1
1.172e-03	-6.75	C11orf52 (chromosome 11 open reading frame 52)	protein interactions	91894	310	5	19454	50	TNIK,ABLIM1,MACF1,FMN2,DTNA
1.226e-03	-6.70	GSC (goosecoid homeobox)	protein interactions	145258	82	3	19454	50	TRPS1,SOX5,NFIA
1.227e-03	-6.70	cartilage condensation	biological process	GO:0001502	19	2	18204	50	BMPR1B,SOX5
1.283e-03	-6.66	dicarboxylic acid transport	biological process	GO:0006835	78	3	18204	50	SLC1A2,NTRK2,SLC1A3
1.290e-03	-6.65	cartilage development	biological process	GO:0051216	173	4	18204	50	NFIA,SOX5,CSGALNACT1,BMPR1B
1.303e-03	-6.64	stomach-carcinoma-intestinal_adenocarcinoma	COSMIC cancer mutations	stomach-carcinoma-intestinal_adenocarcinoma	7225	32	16828	49	RYR3,QKI,NHSL1,NFIA,RFX4,TRPS1,LSAMP,CDH20,PITPNC1,MAML2,ITPR2,ATP1A2,SLC1A2,MACF1,PREX2,RORA,FBXL7,ADCY2,NPAS3,ZBTB20,PRKG1,NTM,SASH1,NTRK2,PTPRZ1,CTNND2,SOX5,SFXN5,FMN2,CSGALNACT1,PARD3B,NEBL
1.303e-03	-6.64	intestinal_adenocarcinoma	COSMIC cancer mutations	intestinal_adenocarcinoma	7225	32	16828	49	MAML2,CDH20,PITPNC1,LSAMP,TRPS1,RFX4,NFIA,NHSL1,QKI,RYR3,FMN2,SFXN5,CSGALNACT1,PARD3B,NEBL,SOX5,CTNND2,NTM,SASH1,NTRK2,PTPRZ1,PRKG1,RORA,MACF1,PREX2,ZBTB20,ADCY2,FBXL7,NPAS3,SLC1A2,ATP1A2,ITPR2
1.318e-03	-6.63	TENM1 (teneurin transmembrane protein 1)	protein interactions	10178	21	2	19454	50	MACF1,SORBS1
1.318e-03	-6.63	ovary-carcinoma	COSMIC cancer mutations	ovary-carcinoma	933	9	16828	49	ITPR2,NTRK2,ATP1A2,PREX2,MACF1,PPP2R2B,PRKG1,BMPR1B,TNIK
1.359e-03	-6.60	cell projection organization	biological process	GO:0030030	1200	10	18204	50	CTNND2,PTPRZ1,PRKG1,BMPR1B,PREX2,CTNNA2,TNIK,ABLIM1,RFX4,GPM6A
1.361e-03	-6.60	positive regulation of chondrocyte differentiation	biological process	GO:0032332	20	2	18204	50	BMPR1B,SOX5
1.361e-03	-6.60	aspartate transmembrane transport	biological process	GO:0015810	20	2	18204	50	SLC1A3,SLC1A2
1.374e-03	-6.59	cGMP-PKG signaling pathway	KEGG pathways	ko04022	163	4	7161	22	ADCY2,ITPR2,PRKG1,ATP1A2
1.374e-03	-6.59	cGMP-PKG signaling pathway	KEGG pathways	hsa04022	163	4	7161	22	ADCY2,ITPR2,PRKG1,ATP1A2
1.397e-03	-6.57	contractile actin filament bundle	cellular component	GO:0097517	86	3	19108	49	NEBL,SORBS1,ABLIM1
1.397e-03	-6.57	stress fiber	cellular component	GO:0001725	86	3	19108	49	NEBL,SORBS1,ABLIM1
1.417e-03	-6.56	Thyroid hormone synthesis	KEGG pathways	hsa04918	74	3	7161	22	ITPR2,ADCY2,ATP1A2
1.417e-03	-6.56	Thyroid hormone synthesis	KEGG pathways	ko04918	74	3	7161	22	ATP1A2,ADCY2,ITPR2
1.473e-03	-6.52	Gastric acid secretion	KEGG pathways	ko04971	75	3	7161	22	ITPR2,ADCY2,ATP1A2
1.473e-03	-6.52	Gastric acid secretion	KEGG pathways	hsa04971	75	3	7161	22	ITPR2,ADCY2,ATP1A2
1.502e-03	-6.50	cell aggregation	biological process	GO:0098743	21	2	18204	50	BMPR1B,SOX5
1.531e-03	-6.48	kidney-other-neoplasm	COSMIC cancer mutations	kidney-other-neoplasm	10653	41	16828	49	MAML2,TPD52L1,MGAT4C,CDH20,LSAMP,TRPS1,RFX4,NHSL1,PPP2R2B,GPM6A,QKI,RYR3,SLC1A3,SPARCL1,SORBS1,FMN2,SFXN5,CSGALNACT1,NEBL,SOX5,CTNND2,GPC5,NTRK2,SASH1,PTPRZ1,NKAIN3,DTNA,TNIK,PRKG1,RORA,PREX2,MACF1,ABLIM1,ZBTB20,NPAS3,ADCY2,FBXL7,ATP1A2,SLC1A2,CPE,ITPR2
1.563e-03	-6.46	haematopoietic_neoplasm	COSMIC cancer mutations	haematopoietic_neoplasm	11082	42	16828	49	RFX4,LSAMP,CDH20,FUT9,MAML2,SPARCL1,SLC1A3,RYR3,QKI,PPP2R2B,NHSL1,BMPR1B,NFIA,DTNA,NKAIN3,PTPRZ1,NTM,SASH1,NTRK2,GPC5,GLIS3,CTNND2,SOX5,PARD3B,NEBL,CSGALNACT1,FMN2,SFXN5,ITPR2,SLC1A2,ATP1A2,CPE,FBXL7,ADCY2,NPAS3,PREX2,MACF1,ABLIM1,RORA,PRKG1,TNIK,MSI2
1.578e-03	-6.45	YWHAH (tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein eta)	protein interactions	7533	1083	9	19454	50	PARD3B,MACF1,ABLIM1,TPD52L1,PITPNC1,SASH1,FMN2,SORBS1,NHSL1
1.582e-03	-6.45	Rbm38 (RNA binding motif protein 38)	protein interactions	56190	23	2	19454	50	QKI,MSI2
1.587e-03	-6.45	regulation of carbohydrate metabolic process	biological process	GO:0006109	183	4	18204	50	ZBTB20,PRKG1,SORBS1,RORA
1.594e-03	-6.44	DEP_dom	interpro domains	IPR000591	22	2	18521	50	PREX2,FMN2
1.595e-03	-6.44	Muscle contraction	REACTOME pathways	R-HSA-397014	204	4	10285	26	ITPR2,ATP1A2,SORBS1,RYR3
1.620e-03	-6.43	OCLN (occludin)	protein interactions	100506658	495	6	19454	50	MACF1,ABLIM1,TNIK,FMN2,NTRK2,DTNA
1.639e-03	-6.41	Glutamate Neurotransmitter Release Cycle	REACTOME pathways	R-HSA-210500	24	2	10285	26	SLC1A2,SLC1A3
1.649e-03	-6.41	negative regulation of muscle contraction	biological process	GO:0045932	22	2	18204	50	ATP1A2,PRKG1
1.649e-03	-6.41	intracellular sodium ion homeostasis	biological process	GO:0006883	22	2	18204	50	ATP1A2,SLC1A3
1.683e-03	-6.39	amino acid:sodium symporter activity	molecular function	GO:0005283	23	2	18094	48	SLC1A2,SLC1A3
1.695e-03	-6.38	actomyosin	cellular component	GO:0042641	92	3	19108	49	SORBS1,NEBL,ABLIM1
1.700e-03	-6.38	transport across blood-brain barrier	biological process	GO:0150104	86	3	18204	50	SLC1A3,ATP1A2,SLC1A2
1.700e-03	-6.38	vascular transport	biological process	GO:0010232	86	3	18204	50	ATP1A2,SLC1A2,SLC1A3
1.748e-03	-6.35	parathyroid-carcinoma	COSMIC cancer mutations	parathyroid-carcinoma	300	5	16828	49	TRPS1,MACF1,PRKG1,GPC5,RYR3
1.751e-03	-6.35	neuron projection	cellular component	GO:0043005	1331	10	19108	49	CTNNA2,SLC1A3,CTNND2,NTRK2,BMPR1B,ATP1A2,ADCY2,GPM6A,DTNA,SLC1A2
1.781e-03	-6.33	ovary-carcinoma-serous_carcinoma	COSMIC cancer mutations	ovary-carcinoma-serous_carcinoma	10710	41	16828	49	QKI,NHSL1,BMPR1B,PPP2R2B,SORBS1,RYR3,SLC1A3,CDH20,MGAT4C,FUT9,MAML2,TRPS1,LSAMP,PREX2,MACF1,RORA,ADCY2,FBXL7,NPAS3,ZBTB20,TNIK,MSI2,PRKG1,ITPR2,SLC1A2,ATP1A2,CPE,SOX5,FMN2,CSGALNACT1,SFXN5,NEBL,PARD3B,SASH1,NTRK2,NTM,DTNA,PTPRZ1,CTNND2,GLIS3,GPC5
1.803e-03	-6.32	relaxation of muscle	biological process	GO:0090075	23	2	18204	50	ATP1A2,PRKG1
1.826e-03	-6.31	oligodendroglioma_Grade_III	COSMIC cancer mutations	oligodendroglioma_Grade_III	303	5	16828	49	MACF1,MGAT4C,FUT9,PTPRZ1,GLIS3
1.911e-03	-6.26	cell-cell junction	cellular component	GO:0005911	513	6	19108	49	ATP1A2,CTNND2,CDH20,SORBS1,PARD3B,CTNNA2
1.913e-03	-6.26	human chr10q11.23-q21.1	chromosome location	human chr10q11.23-q21.1	1	1	26134	50	PRKG1
1.913e-03	-6.26	human chr6q24.3-q25.1	chromosome location	human chr6q24.3-q25.1	1	1	26134	50	SASH1
1.913e-03	-6.26	human chr12q21.31-q21.32	chromosome location	human chr12q21.31-q21.32	1	1	26134	50	MGAT4C
1.913e-03	-6.26	human chr3q26.2-q26.31	chromosome location	human chr3q26.2-q26.31	1	1	26134	50	TNIK
1.913e-03	-6.26	human chr15q13.3-q14	chromosome location	human chr15q13.3-q14	1	1	26134	50	RYR3
1.915e-03	-6.26	actin filament bundle	cellular component	GO:0032432	96	3	19108	49	ABLIM1,NEBL,SORBS1
2.045e-03	-6.19	actin cytoskeleton	cellular component	GO:0015629	520	6	19108	49	ABLIM1,SORBS1,MACF1,CTNNA2,NEBL,FMN2
2.130e-03	-6.15	L-glutamate transmembrane transport	biological process	GO:0015813	25	2	18204	50	SLC1A2,SLC1A3
2.152e-03	-6.14	extrinsic component of plasma membrane	cellular component	GO:0019897	100	3	19108	49	CTNNA2,CDH20,DTNA
2.181e-03	-6.13	MBNL2 (muscleblind like splicing regulator 2)	protein interactions	10150	27	2	19454	50	MSI2,QKI
2.181e-03	-6.13	KCNJ12 (potassium inwardly rectifying channel subfamily J member 12)	protein interactions	3768	27	2	19454	50	DTNA,ABLIM1
2.185e-03	-6.13	LYN (LYN proto-oncogene, Src family tyrosine kinase)	protein interactions	4067	713	7	19454	50	MSI2,FMN2,DTNA,SLC1A3,TNIK,ABLIM1,MACF1
2.200e-03	-6.12	EZR (ezrin)	protein interactions	7430	526	6	19454	50	TNIK,MACF1,ABLIM1,SORBS1,NEBL,DTNA
2.302e-03	-6.07	Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour	COSMIC cancer mutations	Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour	7434	32	16828	49	QKI,PPP2R2B,SORBS1,SLC1A3,SPARCL1,RYR3,MAML2,TPD52L1,TRPS1,ZBTB20,NPAS3,ADCY2,RORA,ABLIM1,MACF1,PREX2,PRKG1,TNIK,ITPR2,ATP1A2,SOX5,PARD3B,NEBL,FMN2,CSGALNACT1,PTPRZ1,DTNA,NKAIN3,SASH1,NTRK2,CTNND2,GLIS3
2.304e-03	-6.07	C4-dicarboxylate transport	biological process	GO:0015740	26	2	18204	50	SLC1A2,SLC1A3
2.332e-03	-6.06	Gap junction	KEGG pathways	hsa04540	88	3	7161	22	PRKG1,ITPR2,ADCY2
2.332e-03	-6.06	Gap junction	KEGG pathways	ko04540	88	3	7161	22	ITPR2,ADCY2,PRKG1
2.341e-03	-6.06	actin filament binding	molecular function	GO:0051015	211	4	18094	48	ABLIM1,CTNNA2,NEBL,MACF1
2.412e-03	-6.03	haematopoietic_and_lymphoid_tissue-spleen-lymphoid_neoplasm-marginal_zone_lymphoma	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue-spleen-lymphoid_neoplasm-marginal_zone_lymphoma	323	5	16828	49	PARD3B,SORBS1,PTPRZ1,ADCY2,NTM
2.424e-03	-6.02	HUNK (hormonally up-regulated Neu-associated kinase)	protein interactions	30811	104	3	19454	50	ABLIM1,SORBS1,SPARCL1
2.476e-03	-6.00	parathyroid	COSMIC cancer mutations	parathyroid	476	6	16828	49	GPC5,PRKG1,GPM6A,RYR3,TRPS1,MACF1
2.570e-03	-5.96	Dynlt1 (dynein light chain Tctex-type 1)	protein interactions	83462	1	1	19454	50	NTRK2
2.570e-03	-5.96	Agtrap (angiotensin II, type I receptor-associated protein)	protein interactions	11610	1	1	19454	50	PITPNC1
2.570e-03	-5.96	Isl1 (ISL1 transcription factor, LIM/homeodomain)	protein interactions	16392	1	1	19454	50	GLIS3
2.570e-03	-5.96	Dcaf7 (DDB1 and CUL4 associated factor 7)	protein interactions	71833	1	1	19454	50	BMPR1B
2.570e-03	-5.96	Hipk3 (homeodomain interacting protein kinase 3)	protein interactions	15259	1	1	19454	50	GLIS3
2.570e-03	-5.96	Bdnf (brain derived neurotrophic factor)	protein interactions	12064	1	1	19454	50	NTRK2
2.570e-03	-5.96	Lztr1 (leucine-zipper-like transcriptional regulator, 1)	protein interactions	66863	1	1	19454	50	BMPR1B
2.570e-03	-5.96	1700006A11Rik (RIKEN cDNA 1700006A11 gene)	protein interactions	71824	1	1	19454	50	BMPR1B
2.614e-03	-5.95	response to alkaloid	biological process	GO:0043279	100	3	18204	50	SLC1A3,SLC1A2,RYR3
2.653e-03	-5.93	internal N(7)-methylguanine-containing RNA reader activity	molecular function	GO:0160089	1	1	18094	48	QKI
2.653e-03	-5.93	peptidoglycan glycosyltransferase activity	molecular function	GO:0008955	1	1	18094	48	CSGALNACT1
2.653e-03	-5.93	brain-derived neurotrophic factor receptor activity	molecular function	GO:0060175	1	1	18094	48	NTRK2
2.670e-03	-5.93	positive regulation of oligodendrocyte differentiation	biological process	GO:0048714	28	2	18204	50	PTPRZ1,QKI
2.673e-03	-5.92	ligand-gated calcium channel activity	molecular function	GO:0099604	29	2	18094	48	ITPR2,RYR3
2.673e-03	-5.92	amino acid:monoatomic cation symporter activity	molecular function	GO:0005416	29	2	18094	48	SLC1A3,SLC1A2
2.681e-03	-5.92	marginal_zone_lymphoma	COSMIC cancer mutations	marginal_zone_lymphoma	331	5	16828	49	NTM,PTPRZ1,SORBS1,ADCY2,PARD3B
2.700e-03	-5.91	M14_CPE_CPD	interpro domains	IPR034232	1	1	18521	50	CPE
2.700e-03	-5.91	SORBS1_SH3	interpro domains	IPR035606	1	1	18521	50	SORBS1
2.700e-03	-5.91	STAR_dimer	interpro domains	IPR032377	1	1	18521	50	QKI
2.700e-03	-5.91	SPARC-like_p1	interpro domains	IPR016359	1	1	18521	50	SPARCL1
2.700e-03	-5.91	TRPS1	interpro domains	IPR028440	1	1	18521	50	TRPS1
2.700e-03	-5.91	NTRK2	interpro domains	IPR020455	1	1	18521	50	NTRK2
2.700e-03	-5.91	Quaking_NLS	interpro domains	IPR032367	1	1	18521	50	QKI
2.700e-03	-5.91	SASH1_SH3	interpro domains	IPR035720	1	1	18521	50	SASH1
2.700e-03	-5.91	Rex2_DEP_1	interpro domains	IPR037367	1	1	18521	50	PREX2
2.700e-03	-5.91	SORBS1_SH3_1	interpro domains	IPR035610	1	1	18521	50	SORBS1
2.700e-03	-5.91	SASH1_SAM_repeat2	interpro domains	IPR037630	1	1	18521	50	SASH1
2.700e-03	-5.91	Nebulette_SH3	interpro domains	IPR035631	1	1	18521	50	NEBL
2.700e-03	-5.91	SASH1_SAM_repeat1	interpro domains	IPR037627	1	1	18521	50	SASH1
2.700e-03	-5.91	MAML2_TAD	interpro domains	IPR048452	1	1	18521	50	MAML2
2.700e-03	-5.91	SORBS1_SH3_2	interpro domains	IPR035611	1	1	18521	50	SORBS1
2.700e-03	-5.91	PKcGMP_CC	interpro domains	IPR031831	1	1	18521	50	PRKG1
2.709e-03	-5.91	large_intestine-caecum-carcinoma-adenocarcinoma	COSMIC cancer mutations	large_intestine-caecum-carcinoma-adenocarcinoma	14236	48	16828	49	RORA,MACF1,ZBTB20,TNIK,PRKG1,CPE,ATP1A2,CSGALNACT1,NEBL,NTM,SASH1,NTRK2,PTPRZ1,NKAIN3,DTNA,CTNND2,QKI,NFIA,BMPR1B,GPM6A,SLC1A3,MGAT4C,FUT9,MAML2,TPD52L1,TRPS1,LSAMP,PREX2,ABLIM1,NPAS3,FBXL7,ADCY2,ITPR2,SLC1A2,SOX5,FMN2,SFXN5,PARD3B,GLIS3,GPC5,NHSL1,PPP2R2B,SORBS1,RYR3,SPARCL1,CDH20,PITPNC1,RFX4
2.733e-03	-5.90	soft_tissue-striated_muscle-rhabdomyosarcoma-alveolar	COSMIC cancer mutations	soft_tissue-striated_muscle-rhabdomyosarcoma-alveolar	2414	15	16828	49	PARD3B,FMN2,CDH20,TRPS1,SASH1,PPP2R2B,NFIA,NHSL1,NPAS3,PREX2,MACF1,SLC1A3,SPARCL1,RYR3,SORBS1
2.733e-03	-5.90	alveolar	COSMIC cancer mutations	alveolar	2414	15	16828	49	NPAS3,MACF1,PREX2,PPP2R2B,NHSL1,NFIA,SORBS1,SPARCL1,SLC1A3,RYR3,CDH20,PARD3B,FMN2,TRPS1,SASH1
2.747e-03	-5.90	Lewis x epitope biosynthetic process	biological process	GO:0106402	1	1	18204	50	FUT9
2.747e-03	-5.90	homologous chromosome movement towards spindle pole in meiosis I anaphase	biological process	GO:0051758	1	1	18204	50	FMN2
2.747e-03	-5.90	negative regulation of calcium:sodium antiporter activity	biological process	GO:1903280	1	1	18204	50	ATP1A2
2.747e-03	-5.90	olfactory cortex development	biological process	GO:0021989	1	1	18204	50	ATP1A2
2.747e-03	-5.90	trans-synaptic signaling by neuropeptide, modulating synaptic transmission	biological process	GO:0099551	1	1	18204	50	NTRK2
2.747e-03	-5.90	trans-synaptic signaling by neuropeptide	biological process	GO:0099540	1	1	18204	50	NTRK2
2.754e-03	-5.89	MAML2_TAD	pfam domains	PF20804	1	1	17795	49	MAML2
2.754e-03	-5.89	STAR_dimer	pfam domains	PF16544	1	1	17795	49	QKI
2.754e-03	-5.89	PKcGMP_CC	pfam domains	PF16808	1	1	17795	49	PRKG1
2.754e-03	-5.89	Quaking_NLS	pfam domains	PF16551	1	1	17795	49	QKI
2.809e-03	-5.87	caecum	COSMIC cancer mutations	caecum	14248	48	16828	49	PREX2,ABLIM1,FBXL7,NPAS3,ADCY2,SLC1A2,ITPR2,SFXN5,FMN2,PARD3B,SOX5,GLIS3,GPC5,NHSL1,PPP2R2B,RYR3,SPARCL1,SORBS1,CDH20,PITPNC1,RFX4,TNIK,PRKG1,MACF1,RORA,ZBTB20,ATP1A2,CPE,CSGALNACT1,NEBL,CTNND2,SASH1,NTRK2,NTM,NKAIN3,DTNA,PTPRZ1,BMPR1B,NFIA,GPM6A,QKI,SLC1A3,TPD52L1,MAML2,FUT9,MGAT4C,LSAMP,TRPS1
2.833e-03	-5.87	-	gene3d domains	1.20.5.4010	1	1	14470	41	QKI
2.857e-03	-5.86	cell body	cellular component	GO:0044297	556	6	19108	49	CTNND2,SLC1A3,ATP1A2,SLC1A2,GPM6A,BMPR1B
2.857e-03	-5.86	catenin complex	cellular component	GO:0016342	31	2	19108	49	CTNNA2,CDH20
2.862e-03	-5.86	ACTB (actin beta)	protein interactions	60	958	8	19454	50	MACF1,ABLIM1,SORBS1,NHSL1,FMN2,DTNA,NEBL,SFXN5
2.901e-03	-5.84	Pancreatic secretion	KEGG pathways	ko04972	95	3	7161	22	ADCY2,ITPR2,ATP1A2
2.901e-03	-5.84	Pancreatic secretion	KEGG pathways	hsa04972	95	3	7161	22	ATP1A2,ITPR2,ADCY2
2.989e-03	-5.81	Circadian entrainment	KEGG pathways	ko04713	96	3	7161	22	RYR3,ADCY2,PRKG1
2.989e-03	-5.81	Circadian entrainment	KEGG pathways	hsa04713	96	3	7161	22	PRKG1,RYR3,ADCY2
2.991e-03	-5.81	TBR1 (T-box brain transcription factor 1)	protein interactions	10716	112	3	19454	50	TRPS1,NFIA,SOX5
2.993e-03	-5.81	YWHAB (tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein beta)	protein interactions	7529	965	8	19454	50	PARD3B,ABLIM1,MACF1,PITPNC1,TPD52L1,SASH1,SORBS1,NHSL1
3.002e-03	-5.81	neural precursor cell proliferation	biological process	GO:0061351	105	3	18204	50	NFIA,RORA,SOX5
3.005e-03	-5.81	SH3_domain	interpro domains	IPR001452	222	4	18521	50	NEBL,SASH1,MACF1,SORBS1
3.044e-03	-5.79	glial cell differentiation	biological process	GO:0010001	219	4	18204	50	QKI,PTPRZ1,NFIA,NTRK2
3.051e-03	-5.79	intracellularly ligand-gated monoatomic ion channel activity	molecular function	GO:0005217	31	2	18094	48	ITPR2,RYR3
3.055e-03	-5.79	CDH1 (cadherin 1)	protein interactions	999	757	7	19454	50	CTNNA2,NHSL1,SORBS1,CTNND2,NEBL,ABLIM1,MACF1
3.057e-03	-5.79	DSG3 (desmoglein 3)	protein interactions	1830	32	2	19454	50	PPP2R2B,CSGALNACT1
3.062e-03	-5.79	L-glutamate import	biological process	GO:0051938	30	2	18204	50	SLC1A3,SLC1A2
3.072e-03	-5.79	upper_aerodigestive_tract-pharynx-carcinoma-squamous_cell_carcinoma	COSMIC cancer mutations	upper_aerodigestive_tract-pharynx-carcinoma-squamous_cell_carcinoma	1485	11	16828	49	FMN2,PARD3B,PREX2,MACF1,FUT9,NPAS3,RYR3,GPC5,DTNA,SORBS1,PTPRZ1
3.093e-03	-5.78	MARK3 (microtubule affinity regulating kinase 3)	protein interactions	4140	235	4	19454	50	NTRK2,PPP2R2B,DTNA,MACF1
3.104e-03	-5.78	upper_aerodigestive_tract	COSMIC cancer mutations	upper_aerodigestive_tract	13181	46	16828	49	CTNND2,NTRK2,SASH1,NTM,DTNA,NKAIN3,PTPRZ1,CSGALNACT1,NEBL,ATP1A2,TNIK,PRKG1,MACF1,RORA,ZBTB20,LSAMP,TRPS1,MAML2,MGAT4C,FUT9,SLC1A3,BMPR1B,NFIA,GPM6A,QKI,GLIS3,GPC5,FMN2,SFXN5,PARD3B,SOX5,SLC1A2,ITPR2,MSI2,ABLIM1,PREX2,NPAS3,FBXL7,ADCY2,RFX4,CDH20,PITPNC1,RYR3,SORBS1,NHSL1,PPP2R2B
3.234e-03	-5.73	cell junction organization	biological process	GO:0034330	532	6	18204	50	CTNND2,SPARCL1,GPM6A,NFIA,SORBS1,CDH20
3.280e-03	-5.72	DAG and IP3 signaling	REACTOME pathways	R-HSA-1489509	34	2	10285	26	ADCY2,ITPR2
3.302e-03	-5.71	SKIL (SKI like proto-oncogene)	protein interactions	6498	116	3	19454	50	MACF1,SASH1,SPARCL1
3.349e-03	-5.70	oesophagus-middle_third-carcinoma-squamous_cell_carcinoma	COSMIC cancer mutations	oesophagus-middle_third-carcinoma-squamous_cell_carcinoma	3531	19	16828	49	SASH1,PTPRZ1,CTNND2,GPC5,SOX5,FMN2,MAML2,NEBL,RYR3,ATP1A2,SPARCL1,MACF1,ABLIM1,PREX2,ZBTB20,ADCY2,TNIK,NHSL1,GPM6A
3.371e-03	-5.69	middle_third	COSMIC cancer mutations	middle_third	3533	19	16828	49	MAML2,FMN2,NEBL,SOX5,CTNND2,GPC5,SASH1,PTPRZ1,TNIK,NHSL1,GPM6A,ABLIM1,PREX2,MACF1,ZBTB20,ADCY2,RYR3,ATP1A2,SPARCL1
3.371e-03	-5.69	YWHAG (tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein gamma)	protein interactions	7532	1211	9	19454	50	SASH1,FMN2,SORBS1,NHSL1,MACF1,ABLIM1,TPD52L1,PITPNC1,PARD3B
3.445e-03	-5.67	brain development	biological process	GO:0007420	724	7	18204	50	ATP1A2,PRKG1,RORA,CTNNA2,SLC1A2,NTRK2,RFX4
3.472e-03	-5.66	monoatomic ion transmembrane transporter activity	molecular function	GO:0015075	752	7	18094	48	GPM6A,ITPR2,SLC1A3,RYR3,SFXN5,ATP1A2,SLC1A2
3.479e-03	-5.66	positive regulation of cartilage development	biological process	GO:0061036	32	2	18204	50	SOX5,BMPR1B
3.479e-03	-5.66	transepithelial transport	biological process	GO:0070633	32	2	18204	50	SLC1A2,SLC1A3
3.482e-03	-5.66	cell adhesion molecule binding	molecular function	GO:0050839	560	6	18094	48	CTNND2,CTNNA2,CPE,MACF1,PTPRZ1,CDH20
3.497e-03	-5.66	pancreas-carcinoma-acinar_carcinoma	COSMIC cancer mutations	pancreas-carcinoma-acinar_carcinoma	1978	13	16828	49	FUT9,SOX5,PARD3B,FMN2,CSGALNACT1,PTPRZ1,SASH1,CTNND2,ZBTB20,QKI,NHSL1,BMPR1B,ATP1A2
3.497e-03	-5.66	acinar_carcinoma	COSMIC cancer mutations	acinar_carcinoma	1978	13	16828	49	PARD3B,FMN2,CSGALNACT1,SOX5,FUT9,CTNND2,PTPRZ1,SASH1,BMPR1B,NHSL1,ZBTB20,QKI,ATP1A2
3.531e-03	-5.65	central_nervous_system-cerebellum-glioma-astrocytoma_Grade_I	COSMIC cancer mutations	central_nervous_system-cerebellum-glioma-astrocytoma_Grade_I	105	3	16828	49	GPC5,PRKG1,QKI
3.557e-03	-5.64	SH3 Domains	gene3d domains	2.30.30.40	223	4	14470	41	MACF1,SASH1,SORBS1,NEBL
3.621e-03	-5.62	serous_carcinoma	COSMIC cancer mutations	serous_carcinoma	10987	41	16828	49	MSI2,TNIK,PRKG1,RORA,MACF1,PREX2,ZBTB20,FBXL7,ADCY2,NPAS3,CPE,ATP1A2,SLC1A2,ITPR2,CSGALNACT1,FMN2,SFXN5,PARD3B,NEBL,SOX5,GLIS3,CTNND2,GPC5,NTM,NTRK2,SASH1,PTPRZ1,DTNA,BMPR1B,NHSL1,PPP2R2B,QKI,RYR3,SLC1A3,SORBS1,MAML2,FUT9,MGAT4C,CDH20,LSAMP,TRPS1
3.649e-03	-5.61	TPRA1 (transmembrane protein adipocyte associated 1)	protein interactions	131601	35	2	19454	50	ITPR2,BMPR1B
3.672e-03	-5.61	PLC-gamma1 signalling	REACTOME pathways	R-HSA-167021	36	2	10285	26	ITPR2,ADCY2
3.672e-03	-5.61	EGFR interacts with phospholipase C-gamma	REACTOME pathways	R-HSA-212718	36	2	10285	26	ITPR2,ADCY2
3.688e-03	-5.60	calcium channel activity	molecular function	GO:0005262	117	3	18094	48	RYR3,ITPR2,GPM6A
3.697e-03	-5.60	response to auditory stimulus	biological process	GO:0010996	33	2	18204	50	ATP1A2,SLC1A3
3.741e-03	-5.59	connective tissue development	biological process	GO:0061448	232	4	18204	50	NFIA,SOX5,CSGALNACT1,BMPR1B
3.808e-03	-5.57	DELLA	smart domains	SM01129	1	1	9717	37	MACF1
3.826e-03	-5.57	NTKRECEPTOR2	prints domains	PR01941	1	1	5227	20	NTRK2
3.871e-03	-5.55	cell adhesion	biological process	GO:0007155	942	8	18204	50	CTNND2,SPARCL1,NTM,CTNNA2,PARD3B,LSAMP,CDH20,SORBS1
3.878e-03	-5.55	organic acid:sodium symporter activity	molecular function	GO:0005343	35	2	18094	48	SLC1A2,SLC1A3
3.921e-03	-5.54	polysaccharide biosynthetic process	biological process	GO:0000271	34	2	18204	50	CSGALNACT1,FUT9
3.936e-03	-5.54	rhabdomyosarcoma	COSMIC cancer mutations	rhabdomyosarcoma	4150	21	16828	49	RYR3,SPARCL1,SLC1A3,SORBS1,NHSL1,NFIA,PPP2R2B,PREX2,MACF1,RORA,NPAS3,ADCY2,CTNND2,GLIS3,SASH1,PTPRZ1,TRPS1,MAML2,FMN2,PARD3B,CDH20
3.969e-03	-5.53	NCK2 (NCK adaptor protein 2)	protein interactions	8440	252	4	19454	50	TNIK,SORBS1,NHSL1,NTRK2
4.005e-03	-5.52	skin-mucosal-malignant_melanoma	COSMIC cancer mutations	skin-mucosal-malignant_melanoma	2009	13	16828	49	MGAT4C,NEBL,FMN2,CTNND2,RORA,PREX2,ABLIM1,PPP2R2B,BMPR1B,SORBS1,CPE,ATP1A2,SPARCL1
4.005e-03	-5.52	mucosal	COSMIC cancer mutations	mucosal	2009	13	16828	49	MGAT4C,NEBL,FMN2,CTNND2,RORA,ABLIM1,PREX2,PPP2R2B,BMPR1B,SORBS1,CPE,ATP1A2,SPARCL1
4.070e-03	-5.50	plasma membrane bounded cell projection	cellular component	GO:0120025	2285	13	19108	49	ATP1A2,ABLIM1,SLC1A2,GPM6A,ADCY2,DTNA,NTRK2,BMPR1B,CTNND2,FMN2,MACF1,CTNNA2,SLC1A3
4.071e-03	-5.50	PADI3 (peptidyl arginine deiminase 3)	protein interactions	51702	37	2	19454	50	CSGALNACT1,SPARCL1
4.071e-03	-5.50	TRNAU1AP (tRNA selenocysteine 1 associated protein 1)	protein interactions	54952	37	2	19454	50	QKI,ZBTB20
4.257e-03	-5.46	response to endogenous stimulus	biological process	GO:0009719	1402	10	18204	50	ATP1A2,RYR3,ITPR2,BMPR1B,SLC1A3,SLC1A2,SORBS1,SOX5,NTRK2,NFIA
4.258e-03	-5.46	EPB41L4A (erythrocyte membrane protein band 4.1 like 4A)	protein interactions	64097	127	3	19454	50	ABLIM1,MACF1,DTNA
4.258e-03	-5.46	PAX9 (paired box 9)	protein interactions	5083	127	3	19454	50	QKI,NFIA,TRPS1
4.290e-03	-5.45	Pcbp1 (poly(rC) binding protein 1)	protein interactions	23983	38	2	19454	50	MSI2,QKI
4.370e-03	-5.43	striated muscle contraction	biological process	GO:0006941	120	3	18204	50	RYR3,DTNA,ATP1A2
4.448e-03	-5.42	Lima1 (LIM domain and actin binding 1)	protein interactions	65970	129	3	19454	50	ITPR2,ZBTB20,ABLIM1
4.455e-03	-5.41	inorganic cation transmembrane transporter activity	molecular function	GO:0022890	589	6	18094	48	ITPR2,GPM6A,SLC1A3,SLC1A2,RYR3,ATP1A2
4.470e-03	-5.41	central_nervous_system-brain-primitive_neuroectodermal_tumour-medulloblastoma-large_cell	COSMIC cancer mutations	central_nervous_system-brain-primitive_neuroectodermal_tumour-medulloblastoma-large_cell	1117	9	16828	49	FMN2,PRKG1,SOX5,CDH20,QKI,ADCY2,RYR3,SLC1A2,GPC5
4.605e-03	-5.38	positive regulation of neurogenesis	biological process	GO:0050769	246	4	18204	50	QKI,PTPRZ1,MACF1,NTRK2
4.607e-03	-5.38	urinary_tract-bladder-carcinoma-transitional_cell_carcinoma	COSMIC cancer mutations	urinary_tract-bladder-carcinoma-transitional_cell_carcinoma	6040	27	16828	49	GLIS3,GPC5,NTRK2,SASH1,PTPRZ1,DTNA,SFXN5,FMN2,PARD3B,NEBL,ATP1A2,ITPR2,PRKG1,ABLIM1,PREX2,MACF1,ZBTB20,ADCY2,TRPS1,RFX4,MGAT4C,CDH20,SLC1A3,SPARCL1,SORBS1,NFIA,GPM6A
4.631e-03	-5.38	positive regulation of glucose import	biological process	GO:0046326	37	2	18204	50	SLC1A2,SORBS1
4.631e-03	-5.37	transitional_cell_carcinoma	COSMIC cancer mutations	transitional_cell_carcinoma	6042	27	16828	49	PREX2,MACF1,ABLIM1,ZBTB20,ADCY2,PRKG1,ITPR2,ATP1A2,FMN2,SFXN5,NEBL,PARD3B,SASH1,NTRK2,PTPRZ1,DTNA,GLIS3,GPC5,NFIA,GPM6A,SORBS1,SLC1A3,SPARCL1,MGAT4C,CDH20,TRPS1,RFX4
4.744e-03	-5.35	CTNNBIP1 (catenin beta interacting protein 1)	protein interactions	56998	40	2	19454	50	PPP2R2B,CTNNA2
4.816e-03	-5.34	gallbladder	COSMIC cancer mutations	gallbladder	2821	16	16828	49	PRKG1,TNIK,NHSL1,MACF1,PREX2,SPARCL1,RYR3,ITPR2,TPD52L1,FMN2,PITPNC1,CTNND2,NKAIN3,TRPS1,PTPRZ1,SASH1
4.816e-03	-5.34	biliary_tract-gallbladder-carcinoma-adenocarcinoma	COSMIC cancer mutations	biliary_tract-gallbladder-carcinoma-adenocarcinoma	2821	16	16828	49	SASH1,NKAIN3,TRPS1,PTPRZ1,CTNND2,PITPNC1,TPD52L1,FMN2,ITPR2,RYR3,SPARCL1,PREX2,MACF1,TNIK,NHSL1,PRKG1
4.835e-03	-5.33	skin-head_neck-malignant_melanoma-superficial_spreading	COSMIC cancer mutations	skin-head_neck-malignant_melanoma-superficial_spreading	923	8	16828	49	ADCY2,MGAT4C,FUT9,MACF1,PREX2,PPP2R2B,SORBS1,CTNND2
4.868e-03	-5.33	dendrite	cellular component	GO:0030425	620	6	19108	49	CTNND2,ADCY2,GPM6A,ATP1A2,BMPR1B,NTRK2
4.880e-03	-5.32	amino acid import across plasma membrane	biological process	GO:0089718	38	2	18204	50	SLC1A3,SLC1A2
4.944e-03	-5.31	dendritic tree	cellular component	GO:0097447	622	6	19108	49	ATP1A2,ADCY2,GPM6A,NTRK2,BMPR1B,CTNND2
4.945e-03	-5.31	NUFIP1 (nuclear FMR1 interacting protein 1)	protein interactions	26747	134	3	19454	50	GPM6A,NTM,CPE
4.963e-03	-5.31	head development	biological process	GO:0060322	774	7	18204	50	CTNNA2,RORA,ATP1A2,PRKG1,RFX4,NTRK2,SLC1A2
4.977e-03	-5.30	striated_muscle	COSMIC cancer mutations	striated_muscle	4228	21	16828	49	SPARCL1,SLC1A3,RYR3,SORBS1,PPP2R2B,NHSL1,NFIA,NPAS3,ADCY2,PREX2,MACF1,RORA,CTNND2,GLIS3,TRPS1,PTPRZ1,SASH1,PARD3B,MAML2,FMN2,CDH20
5.042e-03	-5.29	testis	COSMIC cancer mutations	testis	733	7	16828	49	NTRK2,TRPS1,MACF1,PREX2,TNIK,BMPR1B,PRKG1
5.049e-03	-5.29	Myo1c (myosin IC)	protein interactions	17913	135	3	19454	50	TRPS1,ITPR2,ABLIM1
5.049e-03	-5.29	NTRK2 (neurotrophic receptor tyrosine kinase 2)	protein interactions	4915	135	3	19454	50	ABLIM1,NTRK2,DTNA
5.049e-03	-5.29	FOXP1 (forkhead box P1)	protein interactions	27086	135	3	19454	50	SOX5,NFIA,SASH1
5.109e-03	-5.28	forebrain development	biological process	GO:0030900	408	5	18204	50	NTRK2,RFX4,SLC1A2,PRKG1,ATP1A2
5.127e-03	-5.27	EF-hand-dom_pair	interpro domains	IPR011992	258	4	18521	50	DTNA,RYR3,MACF1,SPARCL1
5.127e-03	-5.27	RHOB (ras homolog family member B)	protein interactions	388	832	7	19454	50	SLC1A3,PARD3B,MACF1,ABLIM1,TNIK,FMN2,DTNA
5.134e-03	-5.27	Sh3kbp1 (SH3-domain kinase binding protein 1)	protein interactions	58194	2	1	19454	50	BMPR1B
5.134e-03	-5.27	Kdm4c (lysine (K)-specific demethylase 4C)	protein interactions	76804	2	1	19454	50	GLIS3
5.134e-03	-5.27	Bmpr2 (bone morphogenetic protein receptor type 2)	protein interactions	12168	2	1	19454	50	BMPR1B
5.134e-03	-5.27	Bcr (BCR activator of RhoGEF and GTPase)	protein interactions	110279	2	1	19454	50	BMPR1B
5.134e-03	-5.27	TRIM39-RPP21 (TRIM39-RPP21 readthrough)	protein interactions	202658	2	1	19454	50	PRKG1
5.134e-03	-5.27	Zmym2 (zinc finger, MYM-type 2)	protein interactions	76007	2	1	19454	50	GLIS3
5.134e-03	-5.27	Fbxo34 (F-box protein 34)	protein interactions	78938	2	1	19454	50	BMPR1B
5.134e-03	-5.27	Irf7 (interferon regulatory factor 7)	protein interactions	54123	2	1	19454	50	BMPR1B
5.134e-03	-5.27	Fkbp1a (FK506 binding protein 1a)	protein interactions	14225	2	1	19454	50	BMPR1B
5.134e-03	-5.27	Mknk2 (MAP kinase-interacting serine/threonine kinase 2)	protein interactions	17347	2	1	19454	50	BMPR1B
5.134e-03	-5.27	Klhl1 (kelch-like 1)	protein interactions	93688	2	1	19454	50	BMPR1B
5.134e-03	-5.27	Ppp3cc (protein phosphatase 3, catalytic subunit, gamma isoform)	protein interactions	19057	2	1	19454	50	BMPR1B
5.134e-03	-5.27	Fkbp1b (FK506 binding protein 1b)	protein interactions	14226	2	1	19454	50	BMPR1B
5.134e-03	-5.27	sodium ion homeostasis	biological process	GO:0055078	39	2	18204	50	SLC1A3,ATP1A2
5.299e-03	-5.24	cGMP-dependent protein kinase activity	molecular function	GO:0004692	2	1	18094	48	PRKG1
5.309e-03	-5.24	Cardiac conduction	REACTOME pathways	R-HSA-5576891	142	3	10285	26	RYR3,ATP1A2,ITPR2
5.366e-03	-5.23	NFIB (nuclear factor I B)	protein interactions	4781	138	3	19454	50	NFIA,SOX5,TRPS1
5.373e-03	-5.23	positive regulation of multicellular organismal process	biological process	GO:0051240	1691	11	18204	50	SOX5,SFXN5,PTPRZ1,MACF1,BMPR1B,NTRK2,QKI,RORA,ZBTB20,ATP1A2,SASH1
5.377e-03	-5.23	somatodendritic compartment	cellular component	GO:0036477	842	7	19108	49	CTNND2,SLC1A3,ADCY2,GPM6A,ATP1A2,BMPR1B,NTRK2
5.392e-03	-5.22	Par3/HAL_N	interpro domains	IPR021922	2	1	18521	50	PARD3B
5.392e-03	-5.22	cGMP_dep_kinase	interpro domains	IPR002374	2	1	18521	50	PRKG1
5.392e-03	-5.22	Formin_Cappuccino_subfam	interpro domains	IPR001265	2	1	18521	50	FMN2
5.392e-03	-5.22	STKc_cGK	interpro domains	IPR035014	2	1	18521	50	PRKG1
5.392e-03	-5.22	MSI_RRM2	interpro domains	IPR034126	2	1	18521	50	MSI2
5.392e-03	-5.22	Distrobrevin	interpro domains	IPR017432	2	1	18521	50	DTNA
5.392e-03	-5.22	Alpha_CARP_receptor-type	interpro domains	IPR041887	2	1	18521	50	PTPRZ1
5.392e-03	-5.22	Osteonectin_CS	interpro domains	IPR001999	2	1	18521	50	SPARCL1
5.395e-03	-5.22	cyclic purine nucleotide metabolic process	biological process	GO:0052652	40	2	18204	50	RORA,ADCY2
5.432e-03	-5.22	Ig_I-set	interpro domains	IPR013098	132	3	18521	50	NTRK2,LSAMP,NTM
5.440e-03	-5.21	sarcoplasmic reticulum membrane	cellular component	GO:0033017	43	2	19108	49	RYR3,ITPR2
5.462e-03	-5.21	lung-carcinoma-adenocarcinoma	COSMIC cancer mutations	lung-carcinoma-adenocarcinoma	15133	49	16828	49	SLC1A2,ITPR2,MSI2,ABLIM1,PREX2,NPAS3,FBXL7,ADCY2,GLIS3,GPC5,FMN2,SFXN5,PARD3B,SOX5,RYR3,SPARCL1,SORBS1,NHSL1,PPP2R2B,RFX4,CDH20,PITPNC1,ATP1A2,CPE,TNIK,PRKG1,MACF1,RORA,ZBTB20,CTNND2,SASH1,NTRK2,NTM,DTNA,NKAIN3,PTPRZ1,CSGALNACT1,NEBL,SLC1A3,BMPR1B,NFIA,GPM6A,QKI,LSAMP,TRPS1,TPD52L1,MAML2,FUT9,MGAT4C
5.486e-03	-5.21	negative regulation of 3'-UTR-mediated mRNA stabilization	biological process	GO:1905869	2	1	18204	50	QKI
5.486e-03	-5.21	UDP-glucuronate metabolic process	biological process	GO:0046398	2	1	18204	50	CSGALNACT1
5.486e-03	-5.21	neuronal stem cell division	biological process	GO:0036445	2	1	18204	50	FUT9
5.486e-03	-5.21	negative regulation of inositol phosphate biosynthetic process	biological process	GO:0010920	2	1	18204	50	PRKG1
5.486e-03	-5.21	myofibroblast contraction	biological process	GO:1990764	2	1	18204	50	QKI
5.486e-03	-5.21	chondroitin sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process	biological process	GO:0050653	2	1	18204	50	CSGALNACT1
5.500e-03	-5.20	Par3_HAL_N_term	pfam domains	PF12053	2	1	17795	49	PARD3B
5.541e-03	-5.20	ZDHHC17 (zinc finger DHHC-type palmitoyltransferase 17)	protein interactions	23390	277	4	19454	50	NEBL,SLC1A3,FUT9,GPM6A
5.545e-03	-5.19	neutral L-amino acid transmembrane transporter activity	molecular function	GO:0015175	42	2	18094	48	SLC1A3,SLC1A2
5.612e-03	-5.18	calcium ion transmembrane transporter activity	molecular function	GO:0015085	136	3	18094	48	GPM6A,ITPR2,RYR3
5.659e-03	-5.17	Vinculin, Vh2 four-helix bundle	gene3d domains	1.20.120.810	2	1	14470	41	CTNNA2
5.659e-03	-5.17	-	gene3d domains	6.20.350.10	2	1	14470	41	RYR3
5.662e-03	-5.17	cyclic nucleotide metabolic process	biological process	GO:0009187	41	2	18204	50	RORA,ADCY2
5.731e-03	-5.16	I-set	pfam domains	PF07679	132	3	17795	49	NTRK2,LSAMP,NTM
5.732e-03	-5.16	Vascular smooth muscle contraction	KEGG pathways	hsa04270	121	3	7161	22	PRKG1,ITPR2,ADCY2
5.732e-03	-5.16	Vascular smooth muscle contraction	KEGG pathways	ko04270	121	3	7161	22	PRKG1,ADCY2,ITPR2
5.755e-03	-5.16	kidney-carcinoma-clear_cell_renal_cell_carcinoma	COSMIC cancer mutations	kidney-carcinoma-clear_cell_renal_cell_carcinoma	13924	47	16828	49	PITPNC1,CDH20,PPP2R2B,NHSL1,SORBS1,SPARCL1,RYR3,SOX5,PARD3B,SFXN5,FMN2,GPC5,GLIS3,NPAS3,FBXL7,ADCY2,ABLIM1,PREX2,MSI2,ITPR2,SLC1A2,FUT9,MGAT4C,MAML2,TPD52L1,TRPS1,LSAMP,QKI,GPM6A,NFIA,BMPR1B,SLC1A3,NEBL,CSGALNACT1,PTPRZ1,DTNA,NKAIN3,NTRK2,SASH1,CTNND2,ZBTB20,RORA,MACF1,PRKG1,TNIK,CPE,ATP1A2
5.755e-03	-5.16	clear_cell_renal_cell_carcinoma	COSMIC cancer mutations	clear_cell_renal_cell_carcinoma	13924	47	16828	49	SORBS1,RYR3,SPARCL1,NHSL1,PPP2R2B,CDH20,PITPNC1,ITPR2,SLC1A2,ABLIM1,PREX2,FBXL7,ADCY2,NPAS3,MSI2,GLIS3,GPC5,SOX5,FMN2,SFXN5,PARD3B,SLC1A3,QKI,BMPR1B,NFIA,GPM6A,TRPS1,LSAMP,MGAT4C,FUT9,TPD52L1,MAML2,ATP1A2,CPE,MACF1,RORA,ZBTB20,TNIK,PRKG1,NTRK2,SASH1,NKAIN3,DTNA,PTPRZ1,CTNND2,CSGALNACT1,NEBL
5.781e-03	-5.15	adenoma	COSMIC cancer mutations	adenoma	2873	16	16828	49	PTPRZ1,NTRK2,SASH1,GPC5,CTNND2,CDH20,SOX5,NEBL,RYR3,ZBTB20,ADCY2,NPAS3,MACF1,PRKG1,GPM6A,BMPR1B
5.802e-03	-5.15	haematopoietic_and_lymphoid_tissue-haematopoietic_neoplasm-mast_cell_neoplasm	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue-haematopoietic_neoplasm-mast_cell_neoplasm	248	4	16828	49	ADCY2,NPAS3,NFIA,GPC5
5.802e-03	-5.15	mast_cell_neoplasm	COSMIC cancer mutations	mast_cell_neoplasm	248	4	16828	49	NPAS3,ADCY2,NFIA,GPC5
5.817e-03	-5.15	regulation of sequestering of calcium ion	biological process	GO:0051282	133	3	18204	50	ATP1A2,RYR3,ITPR2
5.862e-03	-5.14	SH3	prosite domains	PS50002	222	4	12186	40	SASH1,SORBS1,MACF1,NEBL
5.885e-03	-5.14	central_nervous_system-brain-glioma-oligodendroglioma_Grade_III	COSMIC cancer mutations	central_nervous_system-brain-glioma-oligodendroglioma_Grade_III	249	4	16828	49	PTPRZ1,MGAT4C,MACF1,GLIS3
5.935e-03	-5.13	regulation of amino acid transport	biological process	GO:0051955	42	2	18204	50	PRKG1,ATP1A2
5.968e-03	-5.12	small_intestine	COSMIC cancer mutations	small_intestine	250	4	16828	49	MGAT4C,MACF1,CSGALNACT1,TNIK
6.000e-03	-5.12	Platelet activation	KEGG pathways	hsa04611	123	3	7161	22	PRKG1,ITPR2,ADCY2
6.037e-03	-5.11	Calml3 (calmodulin-like 3)	protein interactions	70405	144	3	19454	50	ZBTB20,MACF1,ABLIM1
6.090e-03	-5.10	monoatomic ion transmembrane transport	biological process	GO:0034220	804	7	18204	50	ITPR2,SLC1A2,ATP1A2,RYR3,SLC1A3,GPM6A,SFXN5
6.153e-03	-5.09	cell projection	cellular component	GO:0042995	2398	13	19108	49	BMPR1B,ABLIM1,ATP1A2,GPM6A,DTNA,CTNNA2,MACF1,SLC1A3,FMN2,NTRK2,SLC1A2,ADCY2,CTNND2
6.159e-03	-5.09	monoatomic cation transmembrane transporter activity	molecular function	GO:0008324	630	6	18094	48	SLC1A3,ITPR2,GPM6A,RYR3,ATP1A2,SLC1A2
6.195e-03	-5.08	PLC beta mediated events	REACTOME pathways	R-HSA-112043	47	2	10285	26	ITPR2,ADCY2
6.272e-03	-5.07	PARD3 (par-3 family cell polarity regulator)	protein interactions	56288	287	4	19454	50	SORBS1,PARD3B,DTNA,NTRK2
6.372e-03	-5.06	acute_myeloid_leukaemia	COSMIC cancer mutations	acute_myeloid_leukaemia	10418	39	16828	49	MAML2,CDH20,LSAMP,RFX4,NFIA,NHSL1,PPP2R2B,QKI,RYR3,SLC1A3,SPARCL1,FMN2,SFXN5,CSGALNACT1,NEBL,PARD3B,SOX5,GLIS3,CTNND2,GPC5,NTRK2,NTM,SASH1,PTPRZ1,NKAIN3,MSI2,TNIK,PRKG1,RORA,ABLIM1,PREX2,MACF1,NPAS3,ADCY2,FBXL7,ATP1A2,CPE,SLC1A2,ITPR2
6.372e-03	-5.06	haematopoietic_and_lymphoid_tissue-haematopoietic_neoplasm-acute_myeloid_leukaemia	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue-haematopoietic_neoplasm-acute_myeloid_leukaemia	10418	39	16828	49	ITPR2,ATP1A2,SLC1A2,CPE,RORA,MACF1,ABLIM1,PREX2,ADCY2,FBXL7,NPAS3,MSI2,TNIK,PRKG1,NTM,SASH1,NTRK2,PTPRZ1,NKAIN3,GLIS3,CTNND2,GPC5,SOX5,FMN2,SFXN5,CSGALNACT1,PARD3B,NEBL,RYR3,SLC1A3,SPARCL1,QKI,NFIA,NHSL1,PPP2R2B,RFX4,LSAMP,CDH20,MAML2
6.402e-03	-5.05	skin-extremity-malignant_melanoma	COSMIC cancer mutations	skin-extremity-malignant_melanoma	1875	12	16828	49	RYR3,ADCY2,FBXL7,PREX2,PTPRZ1,NTRK2,SASH1,NEBL,FMN2,PITPNC1,FUT9,CDH20
6.429e-03	-5.05	extremity	COSMIC cancer mutations	extremity	1876	12	16828	49	PITPNC1,CDH20,FUT9,NEBL,FMN2,PTPRZ1,NTRK2,SASH1,ADCY2,FBXL7,PREX2,RYR3
6.435e-03	-5.05	cytoskeleton organization	biological process	GO:0007010	1251	9	18204	50	ABLIM1,PARD3B,SORBS1,FMN2,MACF1,NEBL,PRKG1,TNIK,CTNNA2
6.441e-03	-5.05	membrane raft	cellular component	GO:0045121	290	4	19108	49	ADCY2,SORBS1,SLC1A2,ATP1A2
6.454e-03	-5.04	G-protein mediated events	REACTOME pathways	R-HSA-112040	48	2	10285	26	ADCY2,ITPR2
6.498e-03	-5.04	positive regulation of glucose transmembrane transport	biological process	GO:0010828	44	2	18204	50	SORBS1,SLC1A2
6.500e-03	-5.04	CNTN1 (contactin 1)	protein interactions	1272	47	2	19454	50	PTPRZ1,GPM6A
6.500e-03	-5.04	BDNF (brain derived neurotrophic factor)	protein interactions	627	47	2	19454	50	CPE,NTRK2
6.554e-03	-5.03	OSTEONECTIN_1	prosite domains	PS00612	2	1	12186	40	SPARCL1
6.554e-03	-5.03	OSTEONECTIN_2	prosite domains	PS00613	2	1	12186	40	SPARCL1
6.574e-03	-5.02	actin filament-based process	biological process	GO:0030029	616	6	18204	50	FMN2,NEBL,PRKG1,TNIK,QKI,SORBS1
6.597e-03	-5.02	membrane microdomain	cellular component	GO:0098857	292	4	19108	49	ADCY2,SORBS1,SLC1A2,ATP1A2
6.599e-03	-5.02	SOX2 (SRY-box transcription factor 2)	protein interactions	6657	1342	9	19454	50	MACF1,GLIS3,LSAMP,NFIA,SOX5,QKI,ITPR2,MSI2,TRPS1
6.634e-03	-5.02	GSE1 (Gse1 coiled-coil protein)	protein interactions	23199	149	3	19454	50	TNIK,NFIA,SOX5
6.634e-03	-5.02	vascular process in circulatory system	biological process	GO:0003018	273	4	18204	50	SLC1A3,PRKG1,ATP1A2,SLC1A2
6.645e-03	-5.01	chondroitin biosynthesis	BIOCYC pathways	HUMAN_PWY-6566	2	1	902	3	CSGALNACT1
6.646e-03	-5.01	skin-trunk-malignant_melanoma	COSMIC cancer mutations	skin-trunk-malignant_melanoma	2647	15	16828	49	MAML2,NEBL,MGAT4C,SOX5,CDH20,CTNND2,LSAMP,SASH1,PTPRZ1,TRPS1,PPP2R2B,PREX2,RYR3,SLC1A3,ATP1A2
6.702e-03	-5.01	neurotransmitter transport	biological process	GO:0006836	140	3	18204	50	SLC1A2,ATP1A2,SLC1A3
6.728e-03	-5.00	behavior	biological process	GO:0007610	619	6	18204	50	ATP1A2,PTPRZ1,PREX2,SLC1A2,NTRK2,SLC1A3
6.804e-03	-4.99	gliogenesis	biological process	GO:0042063	275	4	18204	50	QKI,PTPRZ1,NFIA,NTRK2
6.881e-03	-4.98	TNIK (TRAF2 and NCK interacting kinase)	protein interactions	23043	151	3	19454	50	TNIK,MACF1,PRKG1
6.890e-03	-4.98	telencephalon development	biological process	GO:0021537	276	4	18204	50	RFX4,NTRK2,ATP1A2,SLC1A2
6.932e-03	-4.97	embryonal	COSMIC cancer mutations	embryonal	2659	15	16828	49	SPARCL1,RYR3,SORBS1,NFIA,NPAS3,ADCY2,PREX2,MACF1,RORA,CTNND2,GLIS3,PTPRZ1,PARD3B,FMN2,MAML2
6.932e-03	-4.97	soft_tissue-striated_muscle-rhabdomyosarcoma-embryonal	COSMIC cancer mutations	soft_tissue-striated_muscle-rhabdomyosarcoma-embryonal	2659	15	16828	49	PTPRZ1,GLIS3,CTNND2,PARD3B,FMN2,MAML2,SORBS1,SPARCL1,RYR3,ADCY2,NPAS3,PREX2,MACF1,RORA,NFIA
6.941e-03	-4.97	lung-carcinoma-bronchioloalveolar_adenocarcinoma	COSMIC cancer mutations	lung-carcinoma-bronchioloalveolar_adenocarcinoma	778	7	16828	49	ADCY2,SOX5,PRKG1,BMPR1B,TNIK,NTRK2,CTNND2
6.941e-03	-4.97	bronchioloalveolar_adenocarcinoma	COSMIC cancer mutations	bronchioloalveolar_adenocarcinoma	778	7	16828	49	NTRK2,CTNND2,ADCY2,SOX5,PRKG1,BMPR1B,TNIK
6.969e-03	-4.97	neuron migration	biological process	GO:0001764	142	3	18204	50	PRKG1,NTRK2,GPM6A
7.064e-03	-4.95	SP7 (Sp7 transcription factor)	protein interactions	121340	297	4	19454	50	NFIA,QKI,SOX5,TRPS1
7.084e-03	-4.95	positive regulation of glial cell differentiation	biological process	GO:0045687	46	2	18204	50	QKI,PTPRZ1
7.084e-03	-4.95	regulation of oligodendrocyte differentiation	biological process	GO:0048713	46	2	18204	50	PTPRZ1,QKI
7.119e-03	-4.94	oligoastrocytoma_Grade_III	COSMIC cancer mutations	oligoastrocytoma_Grade_III	263	4	16828	49	PREX2,SOX5,RYR3,SLC1A2
7.135e-03	-4.94	SOX6 (SRY-box transcription factor 6)	protein interactions	55553	153	3	19454	50	TRPS1,NFIA,SOX5
7.163e-03	-4.94	EF-hand	gene3d domains	1.10.238.10	272	4	14470	41	SPARCL1,RYR3,MACF1,DTNA
7.191e-03	-4.93	regulation of neuron projection development	biological process	GO:0010975	443	5	18204	50	FUT9,CTNNA2,TNIK,NTRK2,MACF1
7.243e-03	-4.93	glycoprotein biosynthetic process	biological process	GO:0009101	280	4	18204	50	FUT9,CSGALNACT1,MGAT4C,BMPR1B
7.261e-03	-4.93	Chondroitin sulfate/dermatan sulfate metabolism	REACTOME pathways	R-HSA-1793185	51	2	10285	26	GPC5,CSGALNACT1
7.261e-03	-4.93	Neurotransmitter Release Cycle	REACTOME pathways	R-HSA-112310	51	2	10285	26	SLC1A3,SLC1A2
7.263e-03	-4.93	cellular response to oxygen-containing compound	biological process	GO:1901701	1047	8	18204	50	SLC1A3,RORA,RYR3,ZBTB20,ITPR2,ADCY2,SORBS1,SLC1A2
7.394e-03	-4.91	PPP2R2D (protein phosphatase 2 regulatory subunit Bdelta)	protein interactions	55844	155	3	19454	50	CSGALNACT1,GPC5,PPP2R2B
7.404e-03	-4.91	large_intestine-adenoma	COSMIC cancer mutations	large_intestine-adenoma	266	4	16828	49	RYR3,CDH20,SASH1,SOX5
7.515e-03	-4.89	Wnt signaling pathway	biological process	GO:0016055	283	4	18204	50	TNIK,CPE,CTNND2,MACF1
7.521e-03	-4.89	adult behavior	biological process	GO:0030534	146	3	18204	50	PREX2,SLC1A2,ATP1A2
7.521e-03	-4.89	mitotic cell cycle phase transition	biological process	GO:0044772	146	3	18204	50	NFIA,TPD52L1,FBXL7
7.542e-03	-4.89	intracellular signaling cassette	biological process	GO:0141124	837	7	18204	50	ADCY2,TNIK,RYR3,ATP1A2,PRKG1,ITPR2,PREX2
7.592e-03	-4.88	haematopoietic_and_lymphoid_tissue-small_intestine-lymphoid_neoplasm-enteropathy_type_T_cell_lymphoma	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue-small_intestine-lymphoid_neoplasm-enteropathy_type_T_cell_lymphoma	45	2	16828	49	MACF1,MGAT4C
7.592e-03	-4.88	enteropathy_type_T_cell_lymphoma	COSMIC cancer mutations	enteropathy_type_T_cell_lymphoma	45	2	16828	49	MGAT4C,MACF1
7.617e-03	-4.88	Ndc80 (NDC80 kinetochore complex component)	protein interactions	67052	51	2	19454	50	MACF1,NHSL1
7.631e-03	-4.88	human chr8q23.3	chromosome location	human chr8q23.3	4	1	26134	50	TRPS1
7.639e-03	-4.87	CGMPKINASE	prints domains	PR00104	2	1	5227	20	PRKG1
7.639e-03	-4.87	FORMIN	prints domains	PR00828	2	1	5227	20	FMN2
7.691e-03	-4.87	QRFPR (pyroglutamylated RFamide peptide receptor)	protein interactions	84109	3	1	19454	50	NTM
7.691e-03	-4.87	Fbxw5 (F-box and WD-40 domain protein 5)	protein interactions	30839	3	1	19454	50	BMPR1B
7.691e-03	-4.87	Plekhb1 (pleckstrin homology domain containing, family B (evectins) member 1)	protein interactions	27276	3	1	19454	50	BMPR1B
7.691e-03	-4.87	Stk35 (serine/threonine kinase 35)	protein interactions	67333	3	1	19454	50	BMPR1B
7.691e-03	-4.87	Atg16l1 (autophagy related 16 like 1)	protein interactions	77040	3	1	19454	50	BMPR1B
7.691e-03	-4.87	Smad6 (SMAD family member 6)	protein interactions	17130	3	1	19454	50	BMPR1B
7.691e-03	-4.87	Usp45 (ubiquitin specific petidase 45)	protein interactions	77593	3	1	19454	50	BMPR1B
7.691e-03	-4.87	Rap2a (RAS related protein 2a)	protein interactions	76108	3	1	19454	50	BMPR1B
7.691e-03	-4.87	BCO1 (beta-carotene oxygenase 1)	protein interactions	53630	3	1	19454	50	ABLIM1
7.691e-03	-4.87	Spop (speckle-type BTB/POZ protein)	protein interactions	20747	3	1	19454	50	GLIS3
7.691e-03	-4.87	Chn1 (chimerin 1)	protein interactions	108699	3	1	19454	50	BMPR1B
7.691e-03	-4.87	IL34 (interleukin 34)	protein interactions	146433	3	1	19454	50	PTPRZ1
7.700e-03	-4.87	astrocytoma_Grade_I	COSMIC cancer mutations	astrocytoma_Grade_I	139	3	16828	49	QKI,PRKG1,GPC5
7.702e-03	-4.87	animal organ development	biological process	GO:0048513	2846	15	18204	50	NEBL,BMPR1B,CTNNA2,CPE,ABLIM1,SLC1A2,SOX5,CSGALNACT1,ATP1A2,PRKG1,RORA,RFX4,NTRK2,NFIA,GPM6A
7.750e-03	-4.86	diffuse_adenocarcinoma	COSMIC cancer mutations	diffuse_adenocarcinoma	4383	21	16828	49	ATP1A2,SLC1A3,RYR3,PRKG1,GPM6A,NHSL1,ADCY2,QKI,PREX2,MACF1,ABLIM1,CTNND2,GLIS3,PTPRZ1,TRPS1,RFX4,DTNA,SASH1,FMN2,MGAT4C,SOX5
7.750e-03	-4.86	stomach-carcinoma-diffuse_adenocarcinoma	COSMIC cancer mutations	stomach-carcinoma-diffuse_adenocarcinoma	4383	21	16828	49	SLC1A3,ATP1A2,RYR3,ADCY2,QKI,MACF1,ABLIM1,PREX2,PRKG1,GPM6A,NHSL1,TRPS1,PTPRZ1,DTNA,RFX4,SASH1,CTNND2,GLIS3,MGAT4C,SOX5,FMN2
7.832e-03	-4.85	response to organic cyclic compound	biological process	GO:0014070	843	7	18204	50	ADCY2,RORA,SLC1A3,ATP1A2,RYR3,ITPR2,SLC1A2
7.909e-03	-4.84	SH2B2 (SH2B adaptor protein 2)	protein interactions	10603	52	2	19454	50	SORBS1,NTRK2
7.938e-03	-4.84	cysteine transmembrane transporter activity	molecular function	GO:0033229	3	1	18094	48	SLC1A2
7.938e-03	-4.84	alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity	molecular function	GO:0008454	3	1	18094	48	MGAT4C
7.938e-03	-4.84	glucuronylgalactosylproteoglycan 4-beta-N-acetylgalactosaminyltransferase activity	molecular function	GO:0047237	3	1	18094	48	CSGALNACT1
7.938e-03	-4.84	inositol 1,4,5-trisphosphate-gated calcium channel activity	molecular function	GO:0005220	3	1	18094	48	ITPR2
8.007e-03	-4.83	G2/M transition of mitotic cell cycle	biological process	GO:0000086	49	2	18204	50	TPD52L1,FBXL7
8.021e-03	-4.83	YWHAZ (tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein zeta)	protein interactions	7534	1138	8	19454	50	NHSL1,SORBS1,SASH1,PARD3B,TPD52L1,PITPNC1,MACF1,ABLIM1
8.029e-03	-4.82	stomach-adenocarcinoma	COSMIC cancer mutations	stomach-adenocarcinoma	4101	20	16828	49	RORA,QKI,ABLIM1,PREX2,MACF1,PPP2R2B,ITPR2,SLC1A2,ATP1A2,MGAT4C,CDH20,PARD3B,NEBL,FMN2,CSGALNACT1,TRPS1,RFX4,SASH1,GPC5,CTNND2
8.065e-03	-4.82	SOX5 (SRY-box transcription factor 5)	protein interactions	6660	160	3	19454	50	TRPS1,SOX5,NFIA
8.078e-03	-4.82	InsP3_rcpt	interpro domains	IPR000493	3	1	18521	50	ITPR2
8.078e-03	-4.82	SPRY3_RyR	interpro domains	IPR035762	3	1	18521	50	RYR3
8.078e-03	-4.82	NR_DBD_ROR	interpro domains	IPR044101	3	1	18521	50	RORA
8.078e-03	-4.82	SPIDER	interpro domains	IPR021090	3	1	18521	50	SASH1
8.078e-03	-4.82	Vinculin_CS	interpro domains	IPR000633	3	1	18521	50	CTNNA2
8.078e-03	-4.82	Ryanodine_rcpt	interpro domains	IPR003032	3	1	18521	50	RYR3
8.078e-03	-4.82	NTRK_LRRCT	interpro domains	IPR031635	3	1	18521	50	NTRK2
8.078e-03	-4.82	Ryanrecept_TM4-6	interpro domains	IPR009460	3	1	18521	50	RYR3
8.078e-03	-4.82	Myelin_PLP_CS	interpro domains	IPR018237	3	1	18521	50	GPM6A
8.078e-03	-4.82	SPRY2_RyR	interpro domains	IPR035764	3	1	18521	50	RYR3
8.078e-03	-4.82	SoHo_dom	interpro domains	IPR003127	3	1	18521	50	SORBS1
8.078e-03	-4.82	NTRK	interpro domains	IPR020777	3	1	18521	50	NTRK2
8.078e-03	-4.82	MAML1-3	interpro domains	IPR046369	3	1	18521	50	MAML2
8.078e-03	-4.82	RYDR_Jsol	interpro domains	IPR048581	3	1	18521	50	RYR3
8.078e-03	-4.82	SPRY1_RyR	interpro domains	IPR035761	3	1	18521	50	RYR3
8.078e-03	-4.82	Mastermind-like_N	interpro domains	IPR019082	3	1	18521	50	MAML2
8.078e-03	-4.82	MAML_N_sf	interpro domains	IPR046370	3	1	18521	50	MAML2
8.078e-03	-4.82	Myelin_PLP	interpro domains	IPR001614	3	1	18521	50	GPM6A
8.078e-03	-4.82	ROR_rcpt	interpro domains	IPR003079	3	1	18521	50	RORA
8.078e-03	-4.82	Ryan_recept	interpro domains	IPR013333	3	1	18521	50	RYR3
8.079e-03	-4.82	muscle cell differentiation	biological process	GO:0042692	289	4	18204	50	RORA,PRKG1,NEBL,QKI
8.085e-03	-4.82	signaling	biological process	GO:0023052	4968	22	18204	50	ADCY2,SORBS1,ATP1A2,FMN2,PREX2,SLC1A3,MACF1,SPARCL1,MAML2,CPE,TNIK,NTRK2,NFIA,PRKG1,RYR3,PITPNC1,RORA,DTNA,SLC1A2,CTNND2,ITPR2,BMPR1B
8.124e-03	-4.81	neuronal cell body	cellular component	GO:0043025	489	5	19108	49	SLC1A3,BMPR1B,GPM6A,ATP1A2,CTNND2
8.135e-03	-4.81	urinary_tract-bladder-carcinoma	COSMIC cancer mutations	urinary_tract-bladder-carcinoma	14050	47	16828	49	FMN2,SFXN5,PARD3B,SOX5,GLIS3,GPC5,MSI2,ABLIM1,PREX2,ADCY2,NPAS3,FBXL7,SLC1A2,ITPR2,CDH20,PITPNC1,RFX4,PPP2R2B,RYR3,SPARCL1,SORBS1,CSGALNACT1,NEBL,CTNND2,NTM,SASH1,NTRK2,PTPRZ1,DTNA,TNIK,PRKG1,RORA,MACF1,ZBTB20,ATP1A2,CPE,MAML2,TPD52L1,FUT9,MGAT4C,LSAMP,TRPS1,NFIA,BMPR1B,GPM6A,QKI,SLC1A3
8.206e-03	-4.80	MAL2 (mal, T cell differentiation protein 2)	protein interactions	114569	53	2	19454	50	TPD52L1,PITPNC1
8.218e-03	-4.80	trans-synaptic signaling by BDNF, modulating synaptic transmission	biological process	GO:0099183	3	1	18204	50	NTRK2
8.218e-03	-4.80	meiotic chromosome movement towards spindle pole	biological process	GO:0016344	3	1	18204	50	FMN2
8.218e-03	-4.80	cysteine transport	biological process	GO:0042883	3	1	18204	50	SLC1A2
8.218e-03	-4.80	formin-nucleated actin cable assembly	biological process	GO:0070649	3	1	18204	50	FMN2
8.218e-03	-4.80	cardiac muscle thin filament assembly	biological process	GO:0071691	3	1	18204	50	NEBL
8.218e-03	-4.80	UDP-N-acetylgalactosamine metabolic process	biological process	GO:0019276	3	1	18204	50	CSGALNACT1
8.218e-03	-4.80	radial glia guided migration of Purkinje cell	biological process	GO:0021942	3	1	18204	50	CTNNA2
8.218e-03	-4.80	formin-nucleated actin cable organization	biological process	GO:0110009	3	1	18204	50	FMN2
8.218e-03	-4.80	cysteine transmembrane transport	biological process	GO:1903712	3	1	18204	50	SLC1A2
8.218e-03	-4.80	regulation of calcium:sodium antiporter activity	biological process	GO:1903279	3	1	18204	50	ATP1A2
8.238e-03	-4.80	RyR	pfam domains	PF02026	3	1	17795	49	RYR3
8.238e-03	-4.80	Sorb	pfam domains	PF02208	3	1	17795	49	SORBS1
8.238e-03	-4.80	SR_plectin_7	pfam domains	PF21097	3	1	17795	49	MACF1
8.238e-03	-4.80	SLY	pfam domains	PF12485	3	1	17795	49	SASH1
8.238e-03	-4.80	RYDR_Jsol	pfam domains	PF21119	3	1	17795	49	RYR3
8.238e-03	-4.80	LRRCT_2	pfam domains	PF16920	3	1	17795	49	NTRK2
8.238e-03	-4.80	RR_TM4-6	pfam domains	PF06459	3	1	17795	49	RYR3
8.238e-03	-4.80	MamL-1	pfam domains	PF09596	3	1	17795	49	MAML2
8.238e-03	-4.80	Myelin_PLP	pfam domains	PF01275	3	1	17795	49	GPM6A
8.247e-03	-4.80	Apelin signaling pathway	KEGG pathways	hsa04371	138	3	7161	22	ADCY2,RYR3,ITPR2
8.436e-03	-4.78	protein binding	molecular function	GO:0005515	13983	44	18094	48	CPE,LSAMP,CTNNA2,BMPR1B,TPD52L1,FBXL7,NEBL,PTPRZ1,ATP1A2,ABLIM1,PPP2R2B,DTNA,MACF1,SOX5,SLC1A2,NPAS3,PARD3B,SORBS1,NFIA,GPC5,NTRK2,ITPR2,QKI,GPM6A,CDH20,RFX4,TNIK,RORA,SLC1A3,MSI2,MAML2,RYR3,GLIS3,PITPNC1,FMN2,CTNND2,SFXN5,NTM,ADCY2,SASH1,PRKG1,SPARCL1,TRPS1,FUT9
8.476e-03	-4.77	sodium ion transmembrane transporter activity	molecular function	GO:0015081	158	3	18094	48	SLC1A3,ATP1A2,SLC1A2
8.477e-03	-4.77	-	gene3d domains	6.10.250.970	3	1	14470	41	MAML2
8.477e-03	-4.77	-	gene3d domains	6.10.250.2510	3	1	14470	41	CTNNA2
8.477e-03	-4.77	-	gene3d domains	1.10.490.160	3	1	14470	41	RYR3
8.507e-03	-4.77	SYNM (synemin)	protein interactions	23336	54	2	19454	50	PPP2R2B,DTNA
8.546e-03	-4.76	acute_lymphoblastic_leukaemia	COSMIC cancer mutations	acute_lymphoblastic_leukaemia	2197	13	16828	49	SOX5,PARD3B,NTRK2,TRPS1,PTPRZ1,DTNA,PREX2,ADCY2,NFIA,BMPR1B,TNIK,PRKG1,ATP1A2
8.613e-03	-4.75	thyroid-carcinoma	COSMIC cancer mutations	thyroid-carcinoma	4126	20	16828	49	ATP1A2,CPE,SPARCL1,RYR3,ITPR2,PRKG1,NFIA,TNIK,ADCY2,MACF1,GPC5,LSAMP,GLIS3,CTNND2,TRPS1,PTPRZ1,DTNA,SASH1,FUT9,SOX5
8.702e-03	-4.74	hindbrain development	biological process	GO:0030902	154	3	18204	50	RORA,CTNNA2,PRKG1
8.702e-03	-4.74	calcium-mediated signaling	biological process	GO:0019722	154	3	18204	50	ITPR2,ATP1A2,RYR3
8.748e-03	-4.74	ZYX (zyxin)	protein interactions	7791	316	4	19454	50	NEBL,SORBS1,ABLIM1,MACF1
8.771e-03	-4.74	EGR2 (early growth response 2)	protein interactions	1959	165	3	19454	50	NFIA,SOX5,TRPS1
8.771e-03	-4.74	positive regulation of nervous system development	biological process	GO:0051962	296	4	18204	50	NTRK2,PTPRZ1,MACF1,QKI
8.873e-03	-4.72	carboxylic acid transport	biological process	GO:0046942	297	4	18204	50	NTRK2,SLC1A3,SFXN5,SLC1A2
8.873e-03	-4.72	muscle system process	biological process	GO:0003012	297	4	18204	50	ATP1A2,PRKG1,DTNA,RYR3
8.917e-03	-4.72	SCLT1 (sodium channel and clathrin linker 1)	protein interactions	132320	166	3	19454	50	ABLIM1,NEBL,ATP1A2
8.976e-03	-4.71	organic acid transport	biological process	GO:0015849	298	4	18204	50	SFXN5,NTRK2,SLC1A3,SLC1A2
8.978e-03	-4.71	cell communication	biological process	GO:0007154	5010	22	18204	50	SLC1A3,ATP1A2,FMN2,PREX2,ADCY2,SORBS1,CPE,TNIK,SPARCL1,MACF1,MAML2,PITPNC1,RORA,PRKG1,RYR3,NTRK2,NFIA,CTNND2,ITPR2,BMPR1B,DTNA,SLC1A2
8.985e-03	-4.71	positive regulation of biological process	biological process	GO:0048518	6326	26	18204	50	NPAS3,GPM6A,NFIA,NTRK2,ZBTB20,PRKG1,FUT9,RORA,SLC1A2,SOX5,PTPRZ1,BMPR1B,SFXN5,QKI,SORBS1,GLIS3,RFX4,ATP1A2,SASH1,FMN2,TPD52L1,SLC1A3,MAML2,GPC5,MACF1,TNIK
9.053e-03	-4.70	CTNNB1 (catenin beta 1)	protein interactions	1499	926	7	19454	50	CTNNA2,PARD3B,SORBS1,NHSL1,CTNND2,DTNA,PTPRZ1
9.125e-03	-4.70	SEPTIN3 (septin 3)	protein interactions	55964	56	2	19454	50	GPM6A,PRKG1
9.212e-03	-4.69	PPL (periplakin)	protein interactions	5493	168	3	19454	50	NKAIN3,ITPR2,PPP2R2B
9.268e-03	-4.68	Adrenergic signaling in cardiomyocytes	KEGG pathways	ko04261	144	3	7161	22	ATP1A2,PPP2R2B,ADCY2
9.268e-03	-4.68	Adrenergic signaling in cardiomyocytes	KEGG pathways	hsa04261	144	3	7161	22	ADCY2,PPP2R2B,ATP1A2
9.318e-03	-4.68	neutral amino acid transport	biological process	GO:0015804	53	2	18204	50	SLC1A2,SLC1A3
9.442e-03	-4.66	TREX2 (three prime repair exonuclease 2)	protein interactions	11219	57	2	19454	50	PPP2R2B,PARD3B
9.485e-03	-4.66	regulation of plasma membrane bounded cell projection organization	biological process	GO:0120035	666	6	18204	50	GPM6A,NTRK2,MACF1,TNIK,CTNNA2,FUT9
9.492e-03	-4.66	cell cycle phase transition	biological process	GO:0044770	159	3	18204	50	NFIA,TPD52L1,FBXL7
9.621e-03	-4.64	bladder	COSMIC cancer mutations	bladder	14112	47	16828	49	PPP2R2B,SORBS1,RYR3,SPARCL1,CDH20,PITPNC1,RFX4,PREX2,ABLIM1,NPAS3,FBXL7,ADCY2,MSI2,ITPR2,SLC1A2,SOX5,FMN2,SFXN5,PARD3B,GLIS3,GPC5,QKI,NFIA,BMPR1B,GPM6A,SLC1A3,FUT9,MGAT4C,MAML2,TPD52L1,TRPS1,LSAMP,RORA,MACF1,ZBTB20,TNIK,PRKG1,CPE,ATP1A2,CSGALNACT1,NEBL,NTRK2,SASH1,NTM,PTPRZ1,DTNA,CTNND2
9.621e-03	-4.64	urinary_tract	COSMIC cancer mutations	urinary_tract	14112	47	16828	49	FUT9,MGAT4C,MAML2,TPD52L1,TRPS1,LSAMP,QKI,GPM6A,NFIA,BMPR1B,SLC1A3,NEBL,CSGALNACT1,PTPRZ1,DTNA,SASH1,NTRK2,NTM,CTNND2,ZBTB20,RORA,MACF1,PRKG1,TNIK,ATP1A2,CPE,PITPNC1,CDH20,RFX4,PPP2R2B,SORBS1,SPARCL1,RYR3,SOX5,PARD3B,SFXN5,FMN2,GPC5,GLIS3,NPAS3,FBXL7,ADCY2,PREX2,ABLIM1,MSI2,ITPR2,SLC1A2
9.634e-03	-4.64	biliary_tract	COSMIC cancer mutations	biliary_tract	15309	49	16828	49	TRPS1,LSAMP,FUT9,MGAT4C,TPD52L1,MAML2,SLC1A3,QKI,GPM6A,BMPR1B,NFIA,DTNA,NKAIN3,PTPRZ1,SASH1,NTM,NTRK2,CTNND2,NEBL,CSGALNACT1,ATP1A2,CPE,ZBTB20,MACF1,RORA,PRKG1,TNIK,RFX4,PITPNC1,CDH20,SORBS1,SPARCL1,RYR3,PPP2R2B,NHSL1,GPC5,GLIS3,SOX5,PARD3B,SFXN5,FMN2,ITPR2,SLC1A2,ADCY2,FBXL7,NPAS3,PREX2,ABLIM1,MSI2
9.659e-03	-4.64	cell cycle G2/M phase transition	biological process	GO:0044839	54	2	18204	50	FBXL7,TPD52L1
9.751e-03	-4.63	dendritic spine	cellular component	GO:0043197	172	3	19108	49	ATP1A2,GPM6A,NTRK2
9.816e-03	-4.62	MYELIN_PLP_1	prosite domains	PS00575	3	1	12186	40	GPM6A
9.816e-03	-4.62	VINCULIN_1	prosite domains	PS00663	3	1	12186	40	CTNNA2
9.816e-03	-4.62	SOHO	prosite domains	PS50831	3	1	12186	40	SORBS1
9.816e-03	-4.62	MYELIN_PLP_2	prosite domains	PS01004	3	1	12186	40	GPM6A
9.941e-03	-4.61	Signaling by BRAF and RAF fusions	REACTOME pathways	R-HSA-6802952	60	2	10285	26	MACF1,QKI
1.001e-02	-4.60	response to cocaine	biological process	GO:0042220	55	2	18204	50	SLC1A3,SLC1A2
1.002e-02	-4.60	Znf_NHR/GATA	interpro domains	IPR013088	56	2	18521	50	RORA,TRPS1
1.006e-02	-4.60	neuron spine	cellular component	GO:0044309	174	3	19108	49	NTRK2,ATP1A2,GPM6A
1.013e-02	-4.59	DUSP14 (dual specificity phosphatase 14)	protein interactions	11072	174	3	19454	50	CSGALNACT1,QKI,SPARCL1
1.022e-02	-4.58	extrinsic component of membrane	cellular component	GO:0019898	175	3	19108	49	CDH20,DTNA,CTNNA2
1.024e-02	-4.58	Naa20 (N(alpha)-acetyltransferase 20, NatB catalytic subunit)	protein interactions	67877	4	1	19454	50	BMPR1B
1.024e-02	-4.58	Nkiras1 (NFKB inhibitor interacting Ras-like protein 1)	protein interactions	69721	4	1	19454	50	BMPR1B
1.024e-02	-4.58	CCDC126 (coiled-coil domain containing 126)	protein interactions	90693	4	1	19454	50	GPM6A
1.024e-02	-4.58	Tpd52 (tumor protein D52)	protein interactions	21985	4	1	19454	50	TPD52L1
1.024e-02	-4.58	Dnaja1 (DnaJ heat shock protein family (Hsp40) member A1)	protein interactions	15502	4	1	19454	50	GLIS3
1.024e-02	-4.58	Rhebl1 (Ras homolog enriched in brain like 1)	protein interactions	69159	4	1	19454	50	BMPR1B
1.024e-02	-4.58	IER5L (immediate early response 5 like)	protein interactions	389792	4	1	19454	50	PPP2R2B
1.024e-02	-4.58	Nme2 (NME/NM23 nucleoside diphosphate kinase 2)	protein interactions	18103	4	1	19454	50	RORA
1.024e-02	-4.58	Ctbp2 (C-terminal binding protein 2)	protein interactions	13017	4	1	19454	50	TRPS1
1.024e-02	-4.58	Ilkap (integrin-linked kinase-associated serine/threonine phosphatase 2C)	protein interactions	67444	4	1	19454	50	BMPR1B
1.024e-02	-4.58	Srgap1 (SLIT-ROBO Rho GTPase activating protein 1)	protein interactions	117600	4	1	19454	50	BMPR1B
1.024e-02	-4.58	Cdk14 (cyclin dependent kinase 14)	protein interactions	18647	4	1	19454	50	BMPR1B
1.024e-02	-4.58	Arhgef6 (Rac/Cdc42 guanine nucleotide exchange factor 6)	protein interactions	73341	4	1	19454	50	BMPR1B
1.026e-02	-4.58	Ca2+ pathway	REACTOME pathways	R-HSA-4086398	61	2	10285	26	ITPR2,PRKG1
1.029e-02	-4.58	LHX3 (LIM homeobox 3)	protein interactions	8022	175	3	19454	50	SOX5,NFIA,TRPS1
1.034e-02	-4.57	NR3C1 (nuclear receptor subfamily 3 group C member 1)	protein interactions	2908	950	7	19454	50	SLC1A3,ZBTB20,PPP2R2B,CTNND2,TRPS1,ADCY2,NFIA
1.036e-02	-4.57	release of sequestered calcium ion into cytosol	biological process	GO:0051209	56	2	18204	50	RYR3,ITPR2
1.049e-02	-4.56	import across plasma membrane	biological process	GO:0098739	165	3	18204	50	ATP1A2,SLC1A2,SLC1A3
1.057e-02	-4.55	brain-derived neurotrophic factor binding	molecular function	GO:0048403	4	1	18094	48	NTRK2
1.057e-02	-4.55	ryanodine-sensitive calcium-release channel activity	molecular function	GO:0005219	4	1	18094	48	RYR3
1.057e-02	-4.55	tricarboxylic acid transmembrane transporter activity	molecular function	GO:0015142	4	1	18094	48	SFXN5
1.057e-02	-4.55	citrate transmembrane transporter activity	molecular function	GO:0015137	4	1	18094	48	SFXN5
1.061e-02	-4.55	GATA3 (GATA binding protein 3)	protein interactions	2625	177	3	19454	50	NFIA,QKI,TRPS1
1.065e-02	-4.54	ovary-other-neoplasm	COSMIC cancer mutations	ovary-other-neoplasm	12717	44	16828	49	NHSL1,BMPR1B,GPM6A,PPP2R2B,QKI,RYR3,SLC1A3,SPARCL1,SORBS1,MAML2,TPD52L1,MGAT4C,FUT9,CDH20,LSAMP,TRPS1,RFX4,MSI2,TNIK,PRKG1,RORA,ABLIM1,MACF1,PREX2,ZBTB20,FBXL7,ADCY2,SLC1A2,ATP1A2,CPE,ITPR2,SFXN5,FMN2,CSGALNACT1,PARD3B,NEBL,SOX5,GLIS3,CTNND2,GPC5,SASH1,NTM,NTRK2,NKAIN3
1.066e-02	-4.54	regulation of cell projection organization	biological process	GO:0031344	683	6	18204	50	CTNNA2,FUT9,GPM6A,NTRK2,TNIK,MACF1
1.072e-02	-4.54	negative regulation of sequestering of calcium ion	biological process	GO:0051283	57	2	18204	50	ITPR2,RYR3
1.072e-02	-4.54	visual behavior	biological process	GO:0007632	57	2	18204	50	SLC1A2,ATP1A2
1.074e-02	-4.53	Oxytocin signaling pathway	KEGG pathways	hsa04921	152	3	7161	22	ADCY2,ITPR2,RYR3
1.074e-02	-4.53	Oxytocin signaling pathway	KEGG pathways	ko04921	152	3	7161	22	ITPR2,RYR3,ADCY2
1.076e-02	-4.53	CTF/NFI_DNA-bd_N	interpro domains	IPR019548	4	1	18521	50	NFIA
1.076e-02	-4.53	CTF/NFI_DNA-bd_CS	interpro domains	IPR019739	4	1	18521	50	NFIA
1.076e-02	-4.53	Alpha_catenin	interpro domains	IPR001033	4	1	18521	50	CTNNA2
1.076e-02	-4.53	NHS-like	interpro domains	IPR024845	4	1	18521	50	NHSL1
1.076e-02	-4.53	Desmoplakin_Spectrin-like	interpro domains	IPR041573	4	1	18521	50	MACF1
1.076e-02	-4.53	CTF/NFI_DNA-bd-dom	interpro domains	IPR020604	4	1	18521	50	NFIA
1.076e-02	-4.53	AbLIM_anchor	interpro domains	IPR032402	4	1	18521	50	ABLIM1
1.076e-02	-4.53	PP2A_PR55_CS	interpro domains	IPR018067	4	1	18521	50	PPP2R2B
1.076e-02	-4.53	PCN-like_spectrin-like_rpt	interpro domains	IPR049538	4	1	18521	50	MACF1
1.076e-02	-4.53	Glyco_transf_54	interpro domains	IPR006759	4	1	18521	50	MGAT4C
1.076e-02	-4.53	CTF/NFI	interpro domains	IPR000647	4	1	18521	50	NFIA
1.076e-02	-4.53	Na/K-Atpase_Interacting	interpro domains	IPR008516	4	1	18521	50	NKAIN3
1.076e-02	-4.53	PP2A_PR55	interpro domains	IPR000009	4	1	18521	50	PPP2R2B
1.076e-02	-4.53	Nebulin_repeat	interpro domains	IPR000900	4	1	18521	50	NEBL
1.076e-02	-4.53	TPD52	interpro domains	IPR007327	4	1	18521	50	TPD52L1
1.076e-02	-4.53	PRKG1 (protein kinase cGMP-dependent 1)	protein interactions	5592	61	2	19454	50	PRKG1,TNIK
1.090e-02	-4.52	testis-germ_cell_tumour-seminoma	COSMIC cancer mutations	testis-germ_cell_tumour-seminoma	648	6	16828	49	PREX2,PRKG1,BMPR1B,TNIK,TRPS1,NTRK2
1.094e-02	-4.52	regulation of amino acid uptake involved in synaptic transmission	biological process	GO:0051941	4	1	18204	50	ATP1A2
1.094e-02	-4.52	ovarian cumulus expansion	biological process	GO:0001550	4	1	18204	50	BMPR1B
1.094e-02	-4.52	trans-synaptic signaling by BDNF	biological process	GO:0099191	4	1	18204	50	NTRK2
1.094e-02	-4.52	positive regulation of mesenchymal stem cell differentiation	biological process	GO:2000741	4	1	18204	50	SOX5
1.094e-02	-4.52	brain-derived neurotrophic factor receptor signaling pathway	biological process	GO:0031547	4	1	18204	50	NTRK2
1.094e-02	-4.52	N-glycan fucosylation	biological process	GO:0036071	4	1	18204	50	FUT9
1.094e-02	-4.52	response to glycoside	biological process	GO:1903416	4	1	18204	50	ATP1A2
1.094e-02	-4.52	regulation of glutamate uptake involved in transmission of nerve impulse	biological process	GO:0051946	4	1	18204	50	ATP1A2
1.094e-02	-4.52	protein localization to secretory granule	biological process	GO:0033366	4	1	18204	50	CPE
1.095e-02	-4.51	Erythroid Transcription Factor GATA-1, subunit A	gene3d domains	3.30.50.10	56	2	14470	41	TRPS1,RORA
1.097e-02	-4.51	AbLIM_anchor	pfam domains	PF16182	4	1	17795	49	ABLIM1
1.097e-02	-4.51	NfI_DNAbd_pre-N	pfam domains	PF10524	4	1	17795	49	NFIA
1.097e-02	-4.51	NKAIN	pfam domains	PF05640	4	1	17795	49	NKAIN3
1.097e-02	-4.51	Spectrin_3	pfam domains	PF21019	4	1	17795	49	MACF1
1.097e-02	-4.51	Glyco_transf_54	pfam domains	PF04666	4	1	17795	49	MGAT4C
1.097e-02	-4.51	Spectrin_2	pfam domains	PF18373	4	1	17795	49	MACF1
1.097e-02	-4.51	TPD52	pfam domains	PF04201	4	1	17795	49	TPD52L1
1.097e-02	-4.51	Spectrin_4	pfam domains	PF21020	4	1	17795	49	MACF1
1.097e-02	-4.51	Nebulin	pfam domains	PF00880	4	1	17795	49	NEBL
1.097e-02	-4.51	CTF_NFI	pfam domains	PF00859	4	1	17795	49	NFIA
1.097e-02	-4.51	NHS	pfam domains	PF15273	4	1	17795	49	NHSL1
1.098e-02	-4.51	bone-tibia-Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour	COSMIC cancer mutations	bone-tibia-Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour	649	6	16828	49	TNIK,PRKG1,QKI,PREX2,MACF1,ABLIM1
1.098e-02	-4.51	primitive_neuroectodermal_tumour-medulloblastoma	COSMIC cancer mutations	primitive_neuroectodermal_tumour-medulloblastoma	15350	49	16828	49	TRPS1,LSAMP,FUT9,MGAT4C,MAML2,TPD52L1,SLC1A3,QKI,GPM6A,NFIA,BMPR1B,PTPRZ1,NKAIN3,DTNA,SASH1,NTM,NTRK2,CTNND2,NEBL,CSGALNACT1,ATP1A2,CPE,ZBTB20,RORA,MACF1,PRKG1,TNIK,RFX4,PITPNC1,CDH20,SORBS1,SPARCL1,RYR3,PPP2R2B,NHSL1,GPC5,GLIS3,SOX5,PARD3B,SFXN5,FMN2,ITPR2,SLC1A2,NPAS3,FBXL7,ADCY2,PREX2,ABLIM1,MSI2
1.107e-02	-4.50	inorganic molecular entity transmembrane transporter activity	molecular function	GO:0015318	714	6	18094	48	SLC1A3,ITPR2,GPM6A,SLC1A2,RYR3,ATP1A2
1.110e-02	-4.50	ZKSCAN1 (zinc finger with KRAB and SCAN domains 1)	protein interactions	7586	62	2	19454	50	PRKG1,QKI
1.110e-02	-4.50	MYOD1 (myogenic differentiation 1)	protein interactions	4654	180	3	19454	50	NFIA,TRPS1,RORA
1.113e-02	-4.50	Hippo signaling pathway	KEGG pathways	ko04390	154	3	7161	22	BMPR1B,PPP2R2B,CTNNA2
1.113e-02	-4.50	Hippo signaling pathway	KEGG pathways	hsa04390	154	3	7161	22	CTNNA2,PPP2R2B,BMPR1B
1.129e-02	-4.48	-	gene3d domains	1.20.58.1060	4	1	14470	41	MACF1
1.138e-02	-4.48	PLP	smart domains	SM00002	3	1	9717	37	GPM6A
1.138e-02	-4.48	Sorb	smart domains	SM00459	3	1	9717	37	SORBS1
1.138e-02	-4.48	MamL-1	smart domains	SM01275	3	1	9717	37	MAML2
1.143e-02	-4.47	human chr4q34.2	chromosome location	human chr4q34.2	6	1	26134	50	GPM6A
1.143e-02	-4.47	human chr14q13.1	chromosome location	human chr14q13.1	6	1	26134	50	NPAS3
1.144e-02	-4.47	RYANODINER	prints domains	PR00795	3	1	5227	20	RYR3
1.144e-02	-4.47	INSP3RECEPTR	prints domains	PR00779	3	1	5227	20	ITPR2
1.144e-02	-4.47	MYELINPLP	prints domains	PR00214	3	1	5227	20	GPM6A
1.144e-02	-4.47	NTKRECEPTOR	prints domains	PR01939	3	1	5227	20	NTRK2
1.144e-02	-4.47	RORNUCRECPTR	prints domains	PR01293	3	1	5227	20	RORA
1.144e-02	-4.47	PRPH (peripherin)	protein interactions	5630	182	3	19454	50	PPP2R2B,SORBS1,ABLIM1
1.145e-02	-4.47	endochondral bone morphogenesis	biological process	GO:0060350	59	2	18204	50	BMPR1B,CSGALNACT1
1.160e-02	-4.46	skin-lower_leg-malignant_melanoma-nodular	COSMIC cancer mutations	skin-lower_leg-malignant_melanoma-nodular	4	1	16828	49	PREX2
1.160e-02	-4.46	skin-face-malignant_melanoma-superficial_spreading	COSMIC cancer mutations	skin-face-malignant_melanoma-superficial_spreading	4	1	16828	49	PREX2
1.161e-02	-4.46	GSN (gelsolin)	protein interactions	2934	183	3	19454	50	DTNA,PPP2R2B,TNIK
1.167e-02	-4.45	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-peripheral_T_cell_lymphoma_unspecified	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-peripheral_T_cell_lymphoma_unspecified	162	3	16828	49	RYR3,ITPR2,MACF1
1.171e-02	-4.45	Regulation of lipolysis in adipocytes	KEGG pathways	hsa04923	54	2	7161	22	PRKG1,ADCY2
1.175e-02	-4.44	skeletal system development	biological process	GO:0001501	500	5	18204	50	CSGALNACT1,SOX5,TRPS1,NFIA,BMPR1B
1.179e-02	-4.44	VSX1 (visual system homeobox 1)	protein interactions	30813	64	2	19454	50	TRPS1,NFIA
1.179e-02	-4.44	SYNC (syncoilin, intermediate filament protein)	protein interactions	81493	64	2	19454	50	DTNA,MAML2
1.182e-02	-4.44	transmission of nerve impulse	biological process	GO:0019226	60	2	18204	50	NTRK2,ATP1A2
1.182e-02	-4.44	regulation of glucose import	biological process	GO:0046324	60	2	18204	50	SORBS1,SLC1A2
1.182e-02	-4.44	proteoglycan biosynthetic process	biological process	GO:0030166	60	2	18204	50	CSGALNACT1,BMPR1B
1.182e-02	-4.44	regulation of smooth muscle contraction	biological process	GO:0006940	60	2	18204	50	PRKG1,ATP1A2
1.184e-02	-4.44	cadherin binding	molecular function	GO:0045296	335	4	18094	48	CTNND2,CTNNA2,CDH20,MACF1
1.188e-02	-4.43	skin-head_neck-carcinoma-squamous_cell_carcinoma	COSMIC cancer mutations	skin-head_neck-carcinoma-squamous_cell_carcinoma	14191	47	16828	49	SFXN5,FMN2,PARD3B,SOX5,GLIS3,GPC5,PREX2,ABLIM1,NPAS3,FBXL7,ADCY2,SLC1A2,ITPR2,CDH20,PITPNC1,RFX4,NHSL1,PPP2R2B,RYR3,SPARCL1,SORBS1,CSGALNACT1,NEBL,CTNND2,NTM,NTRK2,SASH1,DTNA,NKAIN3,PTPRZ1,TNIK,PRKG1,MACF1,RORA,ZBTB20,ATP1A2,CPE,MAML2,FUT9,MGAT4C,LSAMP,TRPS1,BMPR1B,NFIA,GPM6A,QKI,SLC1A3
1.209e-02	-4.42	kidney	COSMIC cancer mutations	kidney	15380	49	16828	49	TPD52L1,MAML2,FUT9,MGAT4C,LSAMP,TRPS1,GPM6A,BMPR1B,NFIA,QKI,SLC1A3,NEBL,CSGALNACT1,CTNND2,DTNA,NKAIN3,PTPRZ1,NTM,SASH1,NTRK2,PRKG1,TNIK,ZBTB20,MACF1,RORA,CPE,ATP1A2,PITPNC1,CDH20,RFX4,PPP2R2B,NHSL1,SPARCL1,RYR3,SORBS1,PARD3B,SFXN5,FMN2,SOX5,GPC5,GLIS3,MSI2,NPAS3,FBXL7,ADCY2,ABLIM1,PREX2,SLC1A2,ITPR2
1.221e-02	-4.41	germ_cell_tumour	COSMIC cancer mutations	germ_cell_tumour	867	7	16828	49	TRPS1,NTRK2,PRKG1,BMPR1B,TNIK,PREX2,MACF1
1.223e-02	-4.40	cellular response to organonitrogen compound	biological process	GO:0071417	505	5	18204	50	SLC1A3,SORBS1,ITPR2,SLC1A2,RYR3
1.226e-02	-4.40	SH3_2	pfam domains	PF07653	61	2	17795	49	SASH1,SORBS1
1.230e-02	-4.40	regulation of lipid metabolic process	biological process	GO:0019216	327	4	18204	50	ZBTB20,PRKG1,RORA,SORBS1
1.240e-02	-4.39	cell migration	biological process	GO:0016477	921	7	18204	50	CDH20,NTRK2,GPM6A,CTNNA2,PRKG1,GPC5,FMN2
1.248e-02	-4.38	HNF1B (HNF1 homeobox B)	protein interactions	6928	188	3	19454	50	TRPS1,SOX5,NFIA
1.249e-02	-4.38	central nervous system neuron differentiation	biological process	GO:0021953	176	3	18204	50	BMPR1B,NTRK2,RORA
1.250e-02	-4.38	MAML1 (mastermind like transcriptional coactivator 1)	protein interactions	9794	66	2	19454	50	MAML2,NFIA
1.258e-02	-4.38	NGF-independant TRKA activation	REACTOME pathways	R-HSA-187024	5	1	10285	26	NTRK2
1.266e-02	-4.37	peripheral_T_cell_lymphoma_unspecified	COSMIC cancer mutations	peripheral_T_cell_lymphoma_unspecified	167	3	16828	49	MACF1,ITPR2,RYR3
1.279e-02	-4.36	Rhobtb1 (Rho-related BTB domain containing 1)	protein interactions	69288	5	1	19454	50	BMPR1B
1.279e-02	-4.36	SLC10A3 (solute carrier family 10 member 3)	protein interactions	8273	5	1	19454	50	SORBS1
1.279e-02	-4.36	Cdk4 (cyclin dependent kinase 4)	protein interactions	12567	5	1	19454	50	BMPR1B
1.279e-02	-4.36	Rras2 (related RAS viral (r-ras) oncogene 2)	protein interactions	66922	5	1	19454	50	BMPR1B
1.279e-02	-4.36	Rab38 (RAB38, member RAS oncogene family)	protein interactions	72433	5	1	19454	50	BMPR1B
1.279e-02	-4.36	Rab6b (RAB6B, member RAS oncogene family)	protein interactions	270192	5	1	19454	50	BMPR1B
1.279e-02	-4.36	Wwp2 (WW domain containing E3 ubiquitin protein ligase 2)	protein interactions	66894	5	1	19454	50	GLIS3
1.279e-02	-4.36	RFX4 (regulatory factor X4)	protein interactions	5992	5	1	19454	50	RFX4
1.279e-02	-4.36	PPP1R17 (protein phosphatase 1 regulatory subunit 17)	protein interactions	10842	5	1	19454	50	PRKG1
1.279e-02	-4.36	TRH (thyrotropin releasing hormone)	protein interactions	7200	5	1	19454	50	CPE
1.279e-02	-4.36	Rhoj (ras homolog family member J)	protein interactions	80837	5	1	19454	50	BMPR1B
1.282e-02	-4.36	regulation of small molecule metabolic process	biological process	GO:0062012	331	4	18204	50	RORA,SORBS1,PRKG1,ZBTB20
1.304e-02	-4.34	SH3_9	pfam domains	PF14604	63	2	17795	49	NEBL,SORBS1
1.307e-02	-4.34	CTF_NFI_2	prosite domains	PS51080	4	1	12186	40	NFIA
1.307e-02	-4.34	PR55_2	prosite domains	PS01025	4	1	12186	40	PPP2R2B
1.307e-02	-4.34	CTF_NFI_1	prosite domains	PS00349	4	1	12186	40	NFIA
1.307e-02	-4.34	NEBULIN	prosite domains	PS51216	4	1	12186	40	NEBL
1.307e-02	-4.34	PR55_1	prosite domains	PS01024	4	1	12186	40	PPP2R2B
1.308e-02	-4.34	synapse organization	biological process	GO:0050808	333	4	18204	50	GPM6A,NFIA,CTNND2,SPARCL1
1.317e-02	-4.33	carboxylic acid transmembrane transporter activity	molecular function	GO:0046943	186	3	18094	48	SLC1A3,SLC1A2,SFXN5
1.320e-02	-4.33	neurotrophin receptor activity	molecular function	GO:0005030	5	1	18094	48	NTRK2
1.320e-02	-4.33	transforming growth factor beta receptor activity, type I	molecular function	GO:0005025	5	1	18094	48	BMPR1B
1.321e-02	-4.33	non_small_cell_carcinoma	COSMIC cancer mutations	non_small_cell_carcinoma	5198	23	16828	49	MAML2,PITPNC1,LSAMP,TRPS1,BMPR1B,PPP2R2B,QKI,SPARCL1,SLC1A3,SOX5,CTNND2,NTRK2,PTPRZ1,TNIK,MSI2,PRKG1,ABLIM1,PREX2,RORA,FBXL7,ADCY2,NPAS3,ITPR2
1.321e-02	-4.33	lung-carcinoma-non_small_cell_carcinoma	COSMIC cancer mutations	lung-carcinoma-non_small_cell_carcinoma	5198	23	16828	49	SLC1A3,SPARCL1,QKI,PPP2R2B,BMPR1B,TRPS1,LSAMP,PITPNC1,MAML2,ITPR2,ADCY2,NPAS3,FBXL7,RORA,PREX2,ABLIM1,PRKG1,MSI2,TNIK,PTPRZ1,NTRK2,CTNND2,SOX5
1.323e-02	-4.33	CXADR (CXADR Ig-like cell adhesion molecule)	protein interactions	1525	357	4	19454	50	NEBL,TNIK,MACF1,SORBS1
1.326e-02	-4.32	terminal O-glycans residues modification	BIOCYC pathways	META_PWY-7434	4	1	902	3	FUT9
1.327e-02	-4.32	L-amino acid transmembrane transporter activity	molecular function	GO:0015179	66	2	18094	48	SLC1A3,SLC1A2
1.332e-02	-4.32	testis-germ_cell_tumour-non_seminoma	COSMIC cancer mutations	testis-germ_cell_tumour-non_seminoma	487	5	16828	49	PRKG1,BMPR1B,TNIK,NTRK2,MACF1
1.332e-02	-4.32	human chr8q13.2	chromosome location	human chr8q13.2	7	1	26134	50	PREX2
1.332e-02	-4.32	cell division	biological process	GO:0051301	516	5	18204	50	FMN2,FBXL7,FUT9,SOX5,PARD3B
1.335e-02	-4.32	glycoprotein metabolic process	biological process	GO:0009100	335	4	18204	50	BMPR1B,CSGALNACT1,FUT9,MGAT4C
1.335e-02	-4.32	camera-type eye development	biological process	GO:0043010	335	4	18204	50	BMPR1B,GPM6A,NFIA,NTRK2
1.336e-02	-4.32	organic acid transmembrane transporter activity	molecular function	GO:0005342	187	3	18094	48	SLC1A2,SFXN5,SLC1A3
1.337e-02	-4.31	actin filament bundle assembly	biological process	GO:0051017	64	2	18204	50	SORBS1,FMN2
1.339e-02	-4.31	POF1B (POF1B actin binding protein)	protein interactions	79983	193	3	19454	50	CSGALNACT1,PPP2R2B,NKAIN3
1.342e-02	-4.31	salivary_gland-carcinoma-adenoid_cystic_carcinoma	COSMIC cancer mutations	salivary_gland-carcinoma-adenoid_cystic_carcinoma	488	5	16828	49	RYR3,CTNND2,PRKG1,RORA,MGAT4C
1.343e-02	-4.31	PI_transfer	interpro domains	IPR001666	5	1	18521	50	PITPNC1
1.343e-02	-4.31	Follistatin/Osteonectin_EGF	interpro domains	IPR015369	5	1	18521	50	SPARCL1
1.343e-02	-4.31	Vinculin/catenin	interpro domains	IPR006077	5	1	18521	50	CTNNA2
1.343e-02	-4.31	Mtc	interpro domains	IPR004686	5	1	18521	50	SFXN5
1.343e-02	-4.31	BBP-like	interpro domains	IPR045071	5	1	18521	50	QKI
1.354e-02	-4.30	transporter activity	molecular function	GO:0005215	1211	8	18094	48	RYR3,ATP1A2,SFXN5,ITPR2,SLC1A3,GPM6A,PITPNC1,SLC1A2
1.366e-02	-4.29	synaptic signaling via neuropeptide	biological process	GO:0099538	5	1	18204	50	NTRK2
1.366e-02	-4.29	negative regulation of glutamate secretion	biological process	GO:0014050	5	1	18204	50	PRKG1
1.366e-02	-4.29	negative regulation of chondrocyte proliferation	biological process	GO:1902731	5	1	18204	50	BMPR1B
1.366e-02	-4.29	amygdala development	biological process	GO:0021764	5	1	18204	50	ATP1A2
1.366e-02	-4.29	citrate transport	biological process	GO:0015746	5	1	18204	50	SFXN5
1.366e-02	-4.29	polar body extrusion after meiotic divisions	biological process	GO:0040038	5	1	18204	50	FMN2
1.366e-02	-4.29	tricarboxylic acid transport	biological process	GO:0006842	5	1	18204	50	SFXN5
1.367e-02	-4.29	neoplasm	COSMIC cancer mutations	neoplasm	14787	48	16828	49	SPARCL1,RYR3,SORBS1,PPP2R2B,NHSL1,RFX4,CDH20,SLC1A2,ITPR2,MSI2,NPAS3,FBXL7,ADCY2,ABLIM1,PREX2,GPC5,GLIS3,PARD3B,SFXN5,FMN2,SOX5,SLC1A3,GPM6A,BMPR1B,NFIA,QKI,LSAMP,TRPS1,TPD52L1,MAML2,FUT9,MGAT4C,ATP1A2,CPE,PRKG1,TNIK,ZBTB20,MACF1,RORA,CTNND2,NKAIN3,DTNA,PTPRZ1,NTRK2,SASH1,NTM,NEBL,CSGALNACT1
1.369e-02	-4.29	Vinculin	pfam domains	PF01044	5	1	17795	49	CTNNA2
1.369e-02	-4.29	FOLN	pfam domains	PF09289	5	1	17795	49	SPARCL1
1.369e-02	-4.29	IP_trans	pfam domains	PF02121	5	1	17795	49	PITPNC1
1.369e-02	-4.29	SFXNs	pfam domains	PF03820	5	1	17795	49	SFXN5
1.375e-02	-4.29	skin-upper_back-malignant_melanoma	COSMIC cancer mutations	skin-upper_back-malignant_melanoma	319	4	16828	49	FUT9,MACF1,GPC5,PARD3B
1.387e-02	-4.28	non_seminoma	COSMIC cancer mutations	non_seminoma	492	5	16828	49	TNIK,BMPR1B,PRKG1,MACF1,NTRK2
1.399e-02	-4.27	PCDH20 (protocadherin 20)	protein interactions	64881	70	2	19454	50	CTNNA2,MGAT4C
1.403e-02	-4.27	bone-extraskeletal-Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour	COSMIC cancer mutations	bone-extraskeletal-Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour	891	7	16828	49	ATP1A2,SPARCL1,PTPRZ1,ITPR2,PPP2R2B,NPAS3,ABLIM1
1.412e-02	-4.26	membrane protein complex	cellular component	GO:0098796	1261	8	19108	49	BMPR1B,RYR3,SORBS1,SLC1A2,ATP1A2,SLC1A3,CTNNA2,CDH20
1.418e-02	-4.26	liver-carcinoma-hepatocellular_carcinoma	COSMIC cancer mutations	liver-carcinoma-hepatocellular_carcinoma	14800	48	16828	49	NEBL,CSGALNACT1,CTNND2,PTPRZ1,NKAIN3,DTNA,NTM,SASH1,NTRK2,PRKG1,TNIK,ZBTB20,RORA,MACF1,CPE,ATP1A2,MAML2,TPD52L1,MGAT4C,FUT9,LSAMP,TRPS1,GPM6A,NFIA,BMPR1B,QKI,SLC1A3,PARD3B,FMN2,SFXN5,SOX5,GPC5,GLIS3,ADCY2,FBXL7,NPAS3,PREX2,ABLIM1,SLC1A2,ITPR2,PITPNC1,CDH20,RFX4,PPP2R2B,NHSL1,SPARCL1,RYR3,SORBS1
1.418e-02	-4.26	hepatocellular_carcinoma	COSMIC cancer mutations	hepatocellular_carcinoma	14800	48	16828	49	GPC5,GLIS3,SOX5,PARD3B,FMN2,SFXN5,ITPR2,SLC1A2,ADCY2,FBXL7,NPAS3,ABLIM1,PREX2,RFX4,PITPNC1,CDH20,SORBS1,SPARCL1,RYR3,PPP2R2B,NHSL1,PTPRZ1,DTNA,NKAIN3,NTRK2,SASH1,NTM,CTNND2,NEBL,CSGALNACT1,CPE,ATP1A2,ZBTB20,RORA,MACF1,PRKG1,TNIK,TRPS1,LSAMP,MGAT4C,FUT9,MAML2,TPD52L1,SLC1A3,QKI,GPM6A,NFIA,BMPR1B
1.418e-02	-4.26	L-alpha-amino acid transmembrane transport	biological process	GO:1902475	66	2	18204	50	SLC1A2,SLC1A3
1.418e-02	-4.26	cardiac muscle cell development	biological process	GO:0055013	66	2	18204	50	NEBL,PRKG1
1.429e-02	-4.25	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-acute_lymphoblastic_leukaemia	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-acute_lymphoblastic_leukaemia	2081	12	16828	49	ATP1A2,TNIK,BMPR1B,NFIA,PRKG1,PREX2,ADCY2,NTRK2,DTNA,TRPS1,PTPRZ1,SOX5
1.432e-02	-4.25	Long-term depression	KEGG pathways	hsa04730	60	2	7161	22	ITPR2,PRKG1
1.432e-02	-4.25	Long-term depression	KEGG pathways	ko04730	60	2	7161	22	ITPR2,PRKG1
1.433e-02	-4.25	NFIX (nuclear factor I X)	protein interactions	4784	198	3	19454	50	TRPS1,SOX5,NFIA
1.435e-02	-4.24	small_intestine-carcinoid-endocrine_tumour	COSMIC cancer mutations	small_intestine-carcinoid-endocrine_tumour	175	3	16828	49	TNIK,CSGALNACT1,MACF1
1.437e-02	-4.24	CRYBG1 (crystallin beta-gamma domain containing 1)	protein interactions	202	71	2	19454	50	CSGALNACT1,SPARCL1
1.437e-02	-4.24	ANK2 (ankyrin 2)	protein interactions	287	71	2	19454	50	GPM6A,TNIK
1.437e-02	-4.24	HEPHL1 (hephaestin like 1)	protein interactions	341208	71	2	19454	50	PPP2R2B,CSGALNACT1
1.448e-02	-4.24	skin-lower_leg-malignant_melanoma-superficial_spreading	COSMIC cancer mutations	skin-lower_leg-malignant_melanoma-superficial_spreading	5	1	16828	49	PREX2
1.455e-02	-4.23	Corticotropin Activation of Cortisol Production	SMPDB pathways	SMP0000310	5	1	1369	4	ADCY2
1.476e-02	-4.22	DPYSL3 (dihydropyrimidinase like 3)	protein interactions	1809	72	2	19454	50	TNIK,GPM6A
1.476e-02	-4.22	PPP3CC (protein phosphatase 3 catalytic subunit gamma)	protein interactions	5533	72	2	19454	50	PARD3B,BMPR1B
1.485e-02	-4.21	Oncogenic MAPK signaling	REACTOME pathways	R-HSA-6802957	74	2	10285	26	MACF1,QKI
1.492e-02	-4.21	TIAM1 (TIAM Rac1 associated GEF 1)	protein interactions	7074	201	3	19454	50	RYR3,DTNA,ATP1A2
1.500e-02	-4.20	adenoid_cystic_carcinoma	COSMIC cancer mutations	adenoid_cystic_carcinoma	1123	8	16828	49	CTNND2,RYR3,NTRK2,TNIK,MAML2,PRKG1,MGAT4C,RORA
1.501e-02	-4.20	actin filament bundle organization	biological process	GO:0061572	68	2	18204	50	FMN2,SORBS1
1.501e-02	-4.20	extraskeletal	COSMIC cancer mutations	extraskeletal	903	7	16828	49	PPP2R2B,ABLIM1,NPAS3,SPARCL1,ATP1A2,ITPR2,PTPRZ1
1.501e-02	-4.20	lung-carcinoid-endocrine_tumour	COSMIC cancer mutations	lung-carcinoid-endocrine_tumour	502	5	16828	49	NTRK2,SASH1,PRKG1,TNIK,BMPR1B
1.508e-02	-4.19	Activation of TRKA receptors	REACTOME pathways	R-HSA-187015	6	1	10285	26	NTRK2
1.508e-02	-4.19	upper_back	COSMIC cancer mutations	upper_back	328	4	16828	49	MACF1,FUT9,GPC5,PARD3B
1.510e-02	-4.19	regulation of lipid biosynthetic process	biological process	GO:0046890	189	3	18204	50	SORBS1,ZBTB20,PRKG1
1.512e-02	-4.19	FEV (FEV transcription factor, ETS family member)	protein interactions	54738	202	3	19454	50	NFIA,SOX5,TRPS1
1.515e-02	-4.19	NEBU	smart domains	SM00227	4	1	9717	37	NEBL
1.521e-02	-4.19	plasma membrane region	cellular component	GO:0098590	1278	8	19108	49	SLC1A3,TNIK,PARD3B,MACF1,SORBS1,SLC1A2,GPM6A,ATP1A2
1.522e-02	-4.19	ALPHACATENIN	prints domains	PR00805	4	1	5227	20	CTNNA2
1.522e-02	-4.19	PP2APR55	prints domains	PR00600	4	1	5227	20	PPP2R2B
1.531e-02	-4.18	DPYSL2 (dihydropyrimidinase like 2)	protein interactions	1808	203	3	19454	50	TPD52L1,TNIK,GPM6A
1.532e-02	-4.18	SOX11 (SRY-box transcription factor 11)	protein interactions	6664	6	1	19454	50	SOX5
1.532e-02	-4.18	SOX1 (SRY-box transcription factor 1)	protein interactions	6656	6	1	19454	50	SOX5
1.532e-02	-4.18	DRP2 (dystrophin related protein 2)	protein interactions	1821	6	1	19454	50	DTNA
1.532e-02	-4.18	Fancl (Fanconi anemia, complementation group L)	protein interactions	67030	6	1	19454	50	BMPR1B
1.532e-02	-4.18	Zbtb2 (zinc finger and BTB domain containing 2)	protein interactions	381990	6	1	19454	50	SORBS1
1.532e-02	-4.18	Map2k3 (mitogen-activated protein kinase kinase 3)	protein interactions	26397	6	1	19454	50	BMPR1B
1.532e-02	-4.18	PBP2 (Pbp2p)	protein interactions	852533	6	1	19454	50	QKI
1.532e-02	-4.18	GDF6 (growth differentiation factor 6)	protein interactions	392255	6	1	19454	50	BMPR1B
1.532e-02	-4.18	DAZ4 (deleted in azoospermia 4)	protein interactions	57135	6	1	19454	50	QKI
1.532e-02	-4.18	ADCY1 (adenylate cyclase 1)	protein interactions	107	6	1	19454	50	ADCY2
1.532e-02	-4.18	Tiam2 (T cell lymphoma invasion and metastasis 2)	protein interactions	24001	6	1	19454	50	DTNA
1.532e-02	-4.18	GPR135 (G protein-coupled receptor 135)	protein interactions	64582	6	1	19454	50	TPD52L1
1.532e-02	-4.18	Itch (itchy, E3 ubiquitin protein ligase)	protein interactions	16396	6	1	19454	50	GLIS3
1.532e-02	-4.18	CYRIA (CYFIP related Rac1 interactor A)	protein interactions	81553	6	1	19454	50	GPM6A
1.532e-02	-4.18	TPPP3 (tubulin polymerization promoting protein family member 3)	protein interactions	51673	6	1	19454	50	PPP2R2B
1.532e-02	-4.18	SLC12A5 (solute carrier family 12 member 5)	protein interactions	57468	6	1	19454	50	GPM6A
1.532e-02	-4.18	Rhod (ras homolog family member D)	protein interactions	11854	6	1	19454	50	BMPR1B
1.549e-02	-4.17	skin-ear-carcinoma-squamous_cell_carcinoma	COSMIC cancer mutations	skin-ear-carcinoma-squamous_cell_carcinoma	506	5	16828	49	MGAT4C,ZBTB20,NPAS3,PRKG1,SPARCL1
1.549e-02	-4.17	seminoma	COSMIC cancer mutations	seminoma	700	6	16828	49	PREX2,PRKG1,BMPR1B,TNIK,TRPS1,NTRK2
1.550e-02	-4.17	LIM	pfam domains	PF00412	69	2	17795	49	ABLIM1,NEBL
1.552e-02	-4.17	NFIC (nuclear factor I C)	protein interactions	4782	204	3	19454	50	NFIA,SOX5,TRPS1
1.552e-02	-4.17	CASK (calcium/calmodulin dependent serine protein kinase)	protein interactions	8573	204	3	19454	50	ABLIM1,PARD3B,DTNA
1.561e-02	-4.16	monoatomic ion transport	biological process	GO:0006811	964	7	18204	50	ITPR2,SLC1A2,ATP1A2,RYR3,SLC1A3,GPM6A,SFXN5
1.576e-02	-4.15	Znf_LIM	interpro domains	IPR001781	71	2	18521	50	NEBL,ABLIM1
1.581e-02	-4.15	calcium-induced calcium release activity	molecular function	GO:0048763	6	1	18094	48	RYR3
1.581e-02	-4.15	steroid hormone binding	molecular function	GO:1990239	6	1	18094	48	ATP1A2
1.581e-02	-4.15	4-galactosyl-N-acetylglucosaminide 3-alpha-L-fucosyltransferase activity	molecular function	GO:0017083	6	1	18094	48	FUT9
1.581e-02	-4.15	glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity	molecular function	GO:0047238	6	1	18094	48	CSGALNACT1
1.594e-02	-4.14	TXNL4A (thioredoxin like 4A)	protein interactions	10907	75	2	19454	50	TPD52L1,QKI
1.597e-02	-4.14	Synaptic Vesicle Pathway	WikiPathways	WP2267	52	2	5310	20	SLC1A3,ATP1A2
1.600e-02	-4.13	other	COSMIC cancer mutations	other	14843	48	16828	49	SOX5,FMN2,SFXN5,PARD3B,GLIS3,GPC5,ABLIM1,PREX2,FBXL7,NPAS3,ADCY2,MSI2,ITPR2,SLC1A2,CDH20,RFX4,NHSL1,PPP2R2B,SORBS1,RYR3,SPARCL1,CSGALNACT1,NEBL,NTRK2,SASH1,NTM,PTPRZ1,DTNA,NKAIN3,CTNND2,RORA,MACF1,ZBTB20,TNIK,PRKG1,ATP1A2,CPE,FUT9,MGAT4C,MAML2,TPD52L1,TRPS1,LSAMP,QKI,NFIA,BMPR1B,GPM6A,SLC1A3
1.609e-02	-4.13	GAR_dom_sf	interpro domains	IPR036534	6	1	18521	50	MACF1
1.609e-02	-4.13	EF-hand_dom_typ1	interpro domains	IPR015153	6	1	18521	50	DTNA
1.609e-02	-4.13	GAR_dom	interpro domains	IPR003108	6	1	18521	50	MACF1
1.609e-02	-4.13	Glypican	interpro domains	IPR001863	6	1	18521	50	GPC5
1.609e-02	-4.13	Glypican_CS	interpro domains	IPR019803	6	1	18521	50	GPC5
1.609e-02	-4.13	Adcy_conserved_dom	interpro domains	IPR009398	6	1	18521	50	ADCY2
1.609e-02	-4.13	EF-hand_dom_typ2	interpro domains	IPR015154	6	1	18521	50	DTNA
1.609e-02	-4.13	Desmoplakin_SH3	interpro domains	IPR041615	6	1	18521	50	MACF1
1.609e-02	-4.13	P-type_ATPase_IIC	interpro domains	IPR005775	6	1	18521	50	ATP1A2
1.609e-02	-4.13	GLI-like	interpro domains	IPR043359	6	1	18521	50	GLIS3
1.622e-02	-4.12	salivary_gland	COSMIC cancer mutations	salivary_gland	1139	8	16828	49	NTRK2,CTNND2,RYR3,RORA,MGAT4C,PRKG1,TNIK,MAML2
1.627e-02	-4.12	sarcoplasmic reticulum	cellular component	GO:0016529	76	2	19108	49	ITPR2,RYR3
1.635e-02	-4.11	MIR200A (microRNA 200a)	protein interactions	406983	76	2	19454	50	QKI,MSI2
1.637e-02	-4.11	relaxation of vascular associated smooth muscle	biological process	GO:0060087	6	1	18204	50	PRKG1
1.637e-02	-4.11	asymmetric neuroblast division	biological process	GO:0055059	6	1	18204	50	SOX5
1.637e-02	-4.11	establishment of meiotic spindle localization	biological process	GO:0051295	6	1	18204	50	FMN2
1.637e-02	-4.11	fused antrum stage	biological process	GO:0048165	6	1	18204	50	BMPR1B
1.637e-02	-4.11	gamma-aminobutyric acid biosynthetic process	biological process	GO:0009449	6	1	18204	50	SLC1A3
1.637e-02	-4.11	regulation of protein autoubiquitination	biological process	GO:1902498	6	1	18204	50	SASH1
1.640e-02	-4.11	hexosyltransferase activity	molecular function	GO:0016758	202	3	18094	48	CSGALNACT1,FUT9,MGAT4C
1.641e-02	-4.11	SH3_10	pfam domains	PF17902	6	1	17795	49	MACF1
1.641e-02	-4.11	Glypican	pfam domains	PF01153	6	1	17795	49	GPC5
1.641e-02	-4.11	GAS2	pfam domains	PF02187	6	1	17795	49	MACF1
1.641e-02	-4.11	EF-hand_2	pfam domains	PF09068	6	1	17795	49	DTNA
1.641e-02	-4.11	EF-hand_3	pfam domains	PF09069	6	1	17795	49	DTNA
1.641e-02	-4.11	Adcy_cons_dom	pfam domains	PF06327	6	1	17795	49	ADCY2
1.641e-02	-4.11	Plectin	pfam domains	PF00681	6	1	17795	49	MACF1
1.653e-02	-4.10	carbohydrate derivative metabolic process	biological process	GO:1901135	975	7	18204	50	RORA,MGAT4C,ADCY2,FUT9,CSGALNACT1,BMPR1B,ATP1A2
1.656e-02	-4.10	chondroitin biosynthesis	BIOCYC pathways	META_PWY-6566	5	1	902	3	CSGALNACT1
1.672e-02	-4.09	protein N-linked glycosylation	biological process	GO:0006487	72	2	18204	50	MGAT4C,FUT9
1.675e-02	-4.09	ABI1 (abl interactor 1)	protein interactions	10006	210	3	19454	50	SORBS1,SLC1A3,NHSL1
1.676e-02	-4.09	actin cytoskeleton organization	biological process	GO:0030036	547	5	18204	50	SORBS1,TNIK,NEBL,PRKG1,FMN2
1.684e-02	-4.08	Transmission across Chemical Synapses	REACTOME pathways	R-HSA-112315	217	3	10285	26	ADCY2,SLC1A3,SLC1A2
1.688e-02	-4.08	Gas2-like domain	gene3d domains	3.30.920.20	6	1	14470	41	MACF1
1.688e-02	-4.08	Plakin repeat	gene3d domains	3.90.1290.10	6	1	14470	41	MACF1
1.688e-02	-4.08	Single helix bin	gene3d domains	1.20.5.490	6	1	14470	41	PRKG1
1.694e-02	-4.08	signal transduction	biological process	GO:0007165	4637	20	18204	50	SORBS1,ADCY2,NFIA,NTRK2,PITPNC1,RORA,RYR3,ATP1A2,PRKG1,FMN2,PREX2,DTNA,CPE,TNIK,CTNND2,MAML2,SPARCL1,MACF1,BMPR1B,ITPR2
1.709e-02	-4.07	human chr4q22.3	chromosome location	human chr4q22.3	9	1	26134	50	BMPR1B
1.711e-02	-4.07	positive regulation of cell projection organization	biological process	GO:0031346	361	4	18204	50	MACF1,FUT9,GPM6A,NTRK2
1.716e-02	-4.07	cardiac cell development	biological process	GO:0055006	73	2	18204	50	PRKG1,NEBL
1.716e-02	-4.07	peptide metabolic process	biological process	GO:0006518	73	2	18204	50	SLC1A2,CPE
1.716e-02	-4.07	vasculogenesis	biological process	GO:0001570	73	2	18204	50	QKI,NTRK2
1.717e-02	-4.06	Nedd4 (NEDD4 E3 ubiquitin protein ligase)	protein interactions	25489	78	2	19454	50	BMPR1B,NTRK2
1.717e-02	-4.06	MIR34C (microRNA 34c)	protein interactions	407042	78	2	19454	50	QKI,MSI2
1.717e-02	-4.06	ANKRD40 (ankyrin repeat domain 40)	protein interactions	91369	78	2	19454	50	SOX5,MSI2
1.717e-02	-4.06	ATP2B3 (ATPase plasma membrane Ca2+ transporting 3)	protein interactions	492	78	2	19454	50	CSGALNACT1,GPM6A
1.718e-02	-4.06	Calcium signaling pathway	KEGG pathways	hsa04020	181	3	7161	22	ITPR2,RYR3,ADCY2
1.718e-02	-4.06	Calcium signaling pathway	KEGG pathways	ko04020	181	3	7161	22	ITPR2,RYR3,ADCY2
1.735e-02	-4.05	skin-head_neck-malignant_melanoma	COSMIC cancer mutations	skin-head_neck-malignant_melanoma	6	1	16828	49	PREX2
1.735e-02	-4.05	skin-forearm-malignant_melanoma-superficial_spreading	COSMIC cancer mutations	skin-forearm-malignant_melanoma-superficial_spreading	6	1	16828	49	PREX2
1.735e-02	-4.05	autonomic_ganglia-paraganglioma-benign	COSMIC cancer mutations	autonomic_ganglia-paraganglioma-benign	6	1	16828	49	NHSL1
1.743e-02	-4.05	germ cell development	biological process	GO:0007281	363	4	18204	50	PRKG1,FMN2,QKI,BMPR1B
1.744e-02	-4.05	Intracellular Signalling Through PGD2 receptor and Prostaglandin D2	SMPDB pathways	SMP0000343	6	1	1369	4	ADCY2
1.744e-02	-4.05	Dopamine Activation of Neurological Reward System	SMPDB pathways	SMP0000308	6	1	1369	4	ADCY2
1.759e-02	-4.04	PRDM1 (PR/SET domain 1)	protein interactions	639	79	2	19454	50	NFIA,TRPS1
1.761e-02	-4.04	NCK1 (NCK adaptor protein 1)	protein interactions	4690	214	3	19454	50	TNIK,NHSL1,NTRK2
1.761e-02	-4.04	positive regulation of gliogenesis	biological process	GO:0014015	74	2	18204	50	PTPRZ1,QKI
1.765e-02	-4.04	animal organ morphogenesis	biological process	GO:0009887	988	7	18204	50	ABLIM1,SOX5,CSGALNACT1,NTRK2,BMPR1B,CPE,CTNNA2
1.786e-02	-4.03	SASH3 (SAM and SH3 domain containing 3)	protein interactions	54440	7	1	19454	50	BMPR1B
1.786e-02	-4.03	Pum2 (pumilio RNA-binding family member 2)	protein interactions	80913	7	1	19454	50	QKI
1.786e-02	-4.03	ZBTB45 (zinc finger and BTB domain containing 45)	protein interactions	84878	7	1	19454	50	ZBTB20
1.786e-02	-4.03	RGMB (repulsive guidance molecule BMP co-receptor b)	protein interactions	285704	7	1	19454	50	BMPR1B
1.786e-02	-4.03	Fbxo3 (F-box protein 3)	protein interactions	57443	7	1	19454	50	BMPR1B
1.786e-02	-4.03	Uhmk1 (U2AF homology motif (UHM) kinase 1)	protein interactions	16589	7	1	19454	50	BMPR1B
1.786e-02	-4.03	ABCC12 (ATP binding cassette subfamily C member 12)	protein interactions	94160	7	1	19454	50	NPAS3
1.786e-02	-4.03	Smad7 (SMAD family member 7)	protein interactions	17131	7	1	19454	50	BMPR1B
1.786e-02	-4.03	SLC16A5 (solute carrier family 16 member 5)	protein interactions	9121	7	1	19454	50	PTPRZ1
1.786e-02	-4.03	Smurf1 (SMAD specific E3 ubiquitin protein ligase 1)	protein interactions	75788	7	1	19454	50	GLIS3
1.790e-02	-4.02	axonogenesis	biological process	GO:0007409	366	4	18204	50	CTNNA2,BMPR1B,PRKG1,PTPRZ1
1.802e-02	-4.02	Calcium Regulation in the Cardiac Cell	WikiPathways	WP536	151	3	5310	20	ADCY2,RYR3,ITPR2
1.813e-02	-4.01	Cysteine Rich Protein	gene3d domains	2.10.110.10	73	2	14470	41	NEBL,ABLIM1
1.826e-02	-4.00	GFAP (glial fibrillary acidic protein)	protein interactions	2670	217	3	19454	50	ABLIM1,RORA,NKAIN3
1.830e-02	-4.00	Glycosaminoglycan biosynthesis, chondroitin sulfate backbone	KEGG pathways	M00058	6	1	7161	22	CSGALNACT1
1.830e-02	-4.00	Glycosaminoglycan biosynthesis, chondroitin sulfate backbone	KEGG pathways	hsa_M00058	6	1	7161	22	CSGALNACT1
1.836e-02	-4.00	plasma membrane protein complex	cellular component	GO:0098797	600	5	19108	49	CTNNA2,BMPR1B,ATP1A2,CDH20,SORBS1
1.843e-02	-3.99	P-type sodium transporter activity	molecular function	GO:0008554	7	1	18094	48	ATP1A2
1.843e-02	-3.99	mitogen-activated protein kinase p38 binding	molecular function	GO:0048273	7	1	18094	48	PRKG1
1.843e-02	-3.99	P-type sodium:potassium-exchanging transporter activity	molecular function	GO:0005391	7	1	18094	48	ATP1A2
1.843e-02	-3.99	phosphatidic acid transfer activity	molecular function	GO:1990050	7	1	18094	48	PITPNC1
1.843e-02	-3.99	SOX17 (SRY-box transcription factor 17)	protein interactions	64321	81	2	19454	50	NFIA,TRPS1
1.865e-02	-3.98	Protein_kinase_ATP_BS	interpro domains	IPR017441	377	4	18521	50	TNIK,BMPR1B,NTRK2,PRKG1
1.872e-02	-3.98	calcium ion transmembrane transport	biological process	GO:0070588	205	3	18204	50	GPM6A,RYR3,ITPR2
1.875e-02	-3.98	Plakin_repeat_sf	interpro domains	IPR035915	7	1	18521	50	MACF1
1.875e-02	-3.98	Plakophilin/d_Catenin	interpro domains	IPR028435	7	1	18521	50	CTNND2
1.875e-02	-3.98	SPARC/Testican_Ca-bd-dom	interpro domains	IPR019577	7	1	18521	50	SPARCL1
1.875e-02	-3.98	GS_dom	interpro domains	IPR003605	7	1	18521	50	BMPR1B
1.875e-02	-3.98	Alpha-catenin/vinculin-like_sf	interpro domains	IPR036723	7	1	18521	50	CTNNA2
1.875e-02	-3.98	Plectin_repeat	interpro domains	IPR001101	7	1	18521	50	MACF1
1.886e-02	-3.97	TNNT1 (troponin T1, slow skeletal type)	protein interactions	7138	82	2	19454	50	BMPR1B,PRKG1
1.897e-02	-3.96	human chr9p24.2	chromosome location	human chr9p24.2	10	1	26134	50	GLIS3
1.897e-02	-3.96	human chr12p11.23	chromosome location	human chr12p11.23	10	1	26134	50	ITPR2
1.898e-02	-3.96	BMP signaling pathway	biological process	GO:0030509	77	2	18204	50	BMPR1B,NFIA
1.898e-02	-3.96	regulation of organic acid transport	biological process	GO:0032890	77	2	18204	50	PRKG1,ATP1A2
1.898e-02	-3.96	positive regulation of axonogenesis	biological process	GO:0050772	77	2	18204	50	NTRK2,MACF1
1.898e-02	-3.96	neural retina development	biological process	GO:0003407	77	2	18204	50	GPM6A,NTRK2
1.899e-02	-3.96	PITRANSFER	prints domains	PR00391	5	1	5227	20	PITPNC1
1.907e-02	-3.96	chromosome movement towards spindle pole	biological process	GO:0051305	7	1	18204	50	FMN2
1.907e-02	-3.96	regulation of 3'-UTR-mediated mRNA stabilization	biological process	GO:1905868	7	1	18204	50	QKI
1.907e-02	-3.96	cellular response to magnesium ion	biological process	GO:0071286	7	1	18204	50	RYR3
1.907e-02	-3.96	relaxation of smooth muscle	biological process	GO:0044557	7	1	18204	50	PRKG1
1.907e-02	-3.96	regulation of oligodendrocyte progenitor proliferation	biological process	GO:0070445	7	1	18204	50	PTPRZ1
1.907e-02	-3.96	parallel actin filament bundle assembly	biological process	GO:0030046	7	1	18204	50	FMN2
1.907e-02	-3.96	positive regulation of transcription of Notch receptor target	biological process	GO:0007221	7	1	18204	50	MAML2
1.907e-02	-3.96	regulation of testosterone biosynthetic process	biological process	GO:2000224	7	1	18204	50	PRKG1
1.907e-02	-3.96	negative regulation of Arp2/3 complex-mediated actin nucleation	biological process	GO:0034316	7	1	18204	50	CTNNA2
1.907e-02	-3.96	glial cell fate specification	biological process	GO:0021780	7	1	18204	50	NFIA
1.909e-02	-3.96	solute:sodium symporter activity	molecular function	GO:0015370	80	2	18094	48	SLC1A3,SLC1A2
1.912e-02	-3.96	SPARC_Ca_bdg	pfam domains	PF10591	7	1	17795	49	SPARCL1
1.912e-02	-3.96	TGF_beta_GS	pfam domains	PF08515	7	1	17795	49	BMPR1B
1.921e-02	-3.95	caveola	cellular component	GO:0005901	83	2	19108	49	ATP1A2,SORBS1
1.929e-02	-3.95	basal_(triple-negative)_carcinoma	COSMIC cancer mutations	basal_(triple-negative)_carcinoma	2981	15	16828	49	MACF1,ADCY2,NPAS3,MSI2,BMPR1B,PRKG1,PPP2R2B,ATP1A2,SPARCL1,FMN2,MAML2,NEBL,NTM,NTRK2,SASH1
1.929e-02	-3.95	breast-carcinoma-basal_(triple-negative)_carcinoma	COSMIC cancer mutations	breast-carcinoma-basal_(triple-negative)_carcinoma	2981	15	16828	49	NEBL,FMN2,MAML2,NTM,NTRK2,SASH1,PRKG1,PPP2R2B,MSI2,BMPR1B,NPAS3,ADCY2,MACF1,ATP1A2,SPARCL1
1.929e-02	-3.95	Opioid Signalling	REACTOME pathways	R-HSA-111885	85	2	10285	26	ADCY2,ITPR2
1.930e-02	-3.95	PAX2 (paired box 2)	protein interactions	5076	83	2	19454	50	TRPS1,NFIA
1.939e-02	-3.94	YWHAQ (tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein theta)	protein interactions	10971	1076	7	19454	50	MACF1,ABLIM1,TPD52L1,PARD3B,SASH1,SORBS1,NHSL1
1.944e-02	-3.94	positive regulation of carbohydrate metabolic process	biological process	GO:0045913	78	2	18204	50	ZBTB20,SORBS1
1.944e-02	-3.94	regulation of glucose transmembrane transport	biological process	GO:0010827	78	2	18204	50	SLC1A2,SORBS1
1.954e-02	-3.94	SH3-like_dom_sf	interpro domains	IPR036028	212	3	18521	50	NEBL,SASH1,SORBS1
1.954e-02	-3.94	GLYPICAN	prosite domains	PS01207	6	1	12186	40	GPC5
1.954e-02	-3.94	GAR	prosite domains	PS51460	6	1	12186	40	MACF1
1.954e-02	-3.94	transmembrane receptor protein kinase activity	molecular function	GO:0019199	81	2	18094	48	NTRK2,BMPR1B
1.962e-02	-3.93	TGM1 (transglutaminase 1)	protein interactions	7051	223	3	19454	50	PPP2R2B,CSGALNACT1,QKI
1.970e-02	-3.93	Bile secretion	KEGG pathways	ko04976	71	2	7161	22	ADCY2,ATP1A2
1.970e-02	-3.93	Bile secretion	KEGG pathways	hsa04976	71	2	7161	22	ATP1A2,ADCY2
1.973e-02	-3.93	regulation of neurogenesis	biological process	GO:0050767	377	4	18204	50	NTRK2,QKI,MACF1,PTPRZ1
1.985e-02	-3.92	MAPRE3 (microtubule associated protein RP/EB family member 3)	protein interactions	22924	224	3	19454	50	ABLIM1,MACF1,GPM6A
1.991e-02	-3.92	polysaccharide metabolic process	biological process	GO:0005976	79	2	18204	50	FUT9,CSGALNACT1
1.991e-02	-3.92	regulation of glial cell differentiation	biological process	GO:0045685	79	2	18204	50	QKI,PTPRZ1
2.003e-02	-3.91	metal ion binding	molecular function	GO:0046872	4239	18	18094	48	ATP1A2,TRPS1,SPARCL1,RYR3,SLC1A2,ADCY2,SLC1A3,RORA,MACF1,DTNA,CSGALNACT1,ABLIM1,MGAT4C,ZBTB20,BMPR1B,CPE,ITPR2,GLIS3
2.005e-02	-3.91	Release of Hh-Np from the secreting cell	REACTOME pathways	R-HSA-5362798	8	1	10285	26	GPC5
2.008e-02	-3.91	KLF3 (KLF transcription factor 3)	protein interactions	51274	225	3	19454	50	SOX5,NFIA,TRPS1
2.018e-02	-3.90	CFAP298 (cilia and flagella associated protein 298)	protein interactions	56683	85	2	19454	50	FMN2,TRPS1
2.021e-02	-3.90	skin-upper_leg-malignant_melanoma-nodular	COSMIC cancer mutations	skin-upper_leg-malignant_melanoma-nodular	7	1	16828	49	PREX2
2.021e-02	-3.90	skin-face-malignant_melanoma-nodular	COSMIC cancer mutations	skin-face-malignant_melanoma-nodular	7	1	16828	49	PREX2
2.023e-02	-3.90	Adherens junction	KEGG pathways	ko04520	72	2	7161	22	CTNNA2,SORBS1
2.023e-02	-3.90	Adherens junction	KEGG pathways	hsa04520	72	2	7161	22	CTNNA2,SORBS1
2.032e-02	-3.90	Myometrial Relaxation and Contraction Pathways	WikiPathways	WP289	158	3	5310	20	RYR3,ITPR2,ADCY2
2.032e-02	-3.90	Vasopressin Regulation of Water Homeostasis	SMPDB pathways	SMP0000322	7	1	1369	4	ADCY2
2.034e-02	-3.90	HFE-transferrin receptor complex	cellular component	GO:1990712	8	1	19108	49	BMPR1B
2.034e-02	-3.90	zonula adherens	cellular component	GO:0005915	8	1	19108	49	SORBS1
2.038e-02	-3.89	CCK (cholecystokinin)	protein interactions	885	8	1	19454	50	CPE
2.038e-02	-3.89	Rps27a (ribosomal protein S27A)	protein interactions	78294	8	1	19454	50	BMPR1B
2.038e-02	-3.89	Rasd2 (RASD family, member 2)	protein interactions	75141	8	1	19454	50	BMPR1B
2.038e-02	-3.89	DEPP1 (DEPP autophagy regulator 1)	protein interactions	11067	8	1	19454	50	QKI
2.038e-02	-3.89	BMP15 (bone morphogenetic protein 15)	protein interactions	9210	8	1	19454	50	BMPR1B
2.038e-02	-3.89	LHB (luteinizing hormone subunit beta)	protein interactions	3972	8	1	19454	50	NTM
2.038e-02	-3.89	INSM1 (INSM transcriptional repressor 1)	protein interactions	3642	8	1	19454	50	SORBS1
2.042e-02	-3.89	eye development	biological process	GO:0001654	381	4	18204	50	NTRK2,NFIA,GPM6A,BMPR1B
2.063e-02	-3.88	SYNJ1 (synaptojanin 1)	protein interactions	8867	86	2	19454	50	GPM6A,SORBS1
2.067e-02	-3.88	kidney-Wilms_tumour	COSMIC cancer mutations	kidney-Wilms_tumour	545	5	16828	49	PRKG1,FMN2,BMPR1B,TNIK,NTRK2
2.082e-02	-3.87	Wilms_tumour	COSMIC cancer mutations	Wilms_tumour	546	5	16828	49	PRKG1,FMN2,BMPR1B,TNIK,NTRK2
2.087e-02	-3.87	adult locomotory behavior	biological process	GO:0008344	81	2	18204	50	PREX2,ATP1A2
2.101e-02	-3.86	EF_hand_dom	interpro domains	IPR002048	218	3	18521	50	SPARCL1,MACF1,RYR3
2.103e-02	-3.86	P-type potassium transmembrane transporter activity	molecular function	GO:0008556	8	1	18094	48	ATP1A2
2.103e-02	-3.86	BMP receptor activity	molecular function	GO:0098821	8	1	18094	48	BMPR1B
2.103e-02	-3.86	sodium ion binding	molecular function	GO:0031402	8	1	18094	48	ATP1A2
2.103e-02	-3.86	cyclic nucleotide-dependent protein kinase activity	molecular function	GO:0004690	8	1	18094	48	PRKG1
2.103e-02	-3.86	glutamate binding	molecular function	GO:0016595	8	1	18094	48	SLC1A3
2.103e-02	-3.86	alpha-(1->3)-fucosyltransferase activity	molecular function	GO:0046920	8	1	18094	48	FUT9
2.103e-02	-3.86	cellular response to nitrogen compound	biological process	GO:1901699	580	5	18204	50	ITPR2,SLC1A2,RYR3,SLC1A3,SORBS1
2.103e-02	-3.86	-	gene3d domains	2.80.10.50	79	2	14470	41	ITPR2,RYR3
2.105e-02	-3.86	glutamatergic synapse	cellular component	GO:0098978	412	4	19108	49	SLC1A2,GPM6A,SPARCL1,TNIK
2.106e-02	-3.86	eye-uveal_tract-malignant_melanoma-spindle	COSMIC cancer mutations	eye-uveal_tract-malignant_melanoma-spindle	363	4	16828	49	CPE,CTNND2,PREX2,MACF1
2.108e-02	-3.86	ZNF608 (zinc finger protein 608)	protein interactions	57507	87	2	19454	50	NFIA,SOX5
2.108e-02	-3.86	NHLH1 (nescient helix-loop-helix 1)	protein interactions	4807	87	2	19454	50	NFIA,TRPS1
2.108e-02	-3.86	MIR141 (microRNA 141)	protein interactions	406933	87	2	19454	50	MSI2,QKI
2.108e-02	-3.86	Kctd5 (potassium channel tetramerisation domain containing 5)	protein interactions	69259	87	2	19454	50	SLC1A3,TRPS1
2.113e-02	-3.86	visual system development	biological process	GO:0150063	385	4	18204	50	BMPR1B,NTRK2,GPM6A,NFIA
2.127e-02	-3.85	DST (dystonin)	protein interactions	667	230	3	19454	50	TNIK,ATP1A2,NTRK2
2.140e-02	-3.84	Chond_GalNAc	interpro domains	IPR008428	8	1	18521	50	CSGALNACT1
2.140e-02	-3.84	Glyco_trans_10	interpro domains	IPR001503	8	1	18521	50	FUT9
2.140e-02	-3.84	GT10-like_C_sf	interpro domains	IPR038577	8	1	18521	50	FUT9
2.140e-02	-3.84	Adcy	interpro domains	IPR030672	8	1	18521	50	ADCY2
2.140e-02	-3.84	Villin_headpiece	interpro domains	IPR003128	8	1	18521	50	ABLIM1
2.140e-02	-3.84	RFX-like	interpro domains	IPR039779	8	1	18521	50	RFX4
2.140e-02	-3.84	Villin_headpiece_dom_sf	interpro domains	IPR036886	8	1	18521	50	ABLIM1
2.140e-02	-3.84	Plakin	interpro domains	IPR043197	8	1	18521	50	MACF1
2.140e-02	-3.84	Glyco_tran_10_N	interpro domains	IPR031481	8	1	18521	50	FUT9
2.140e-02	-3.84	AC_N	interpro domains	IPR032628	8	1	18521	50	ADCY2
2.140e-02	-3.84	positive regulation of cellular process	biological process	GO:0048522	5719	23	18204	50	TNIK,MACF1,GPC5,MAML2,RFX4,SORBS1,GLIS3,QKI,SLC1A3,TPD52L1,FMN2,SASH1,SOX5,SLC1A2,BMPR1B,PTPRZ1,NTRK2,NFIA,GPM6A,NPAS3,RORA,FUT9,ZBTB20
2.153e-02	-3.84	RAP2A (RAP2A, member of RAS oncogene family)	protein interactions	5911	88	2	19454	50	TNIK,BMPR1B
2.168e-02	-3.83	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-hairy_cell_leukaemia	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-hairy_cell_leukaemia	1440	9	16828	49	RYR3,CTNND2,PTPRZ1,RFX4,FMN2,NEBL,CDH20,MACF1,PREX2
2.168e-02	-3.83	hairy_cell_leukaemia	COSMIC cancer mutations	hairy_cell_leukaemia	1440	9	16828	49	RYR3,CTNND2,RFX4,PTPRZ1,NEBL,FMN2,MACF1,CDH20,PREX2
2.170e-02	-3.83	Sudden Infant Death Syndrome (SIDS) Susceptibility Pathways	WikiPathways	WP706	162	3	5310	20	NTRK2,RORA,SLC1A3
2.177e-02	-3.83	regulation of synapse structural plasticity	biological process	GO:0051823	8	1	18204	50	CTNNA2
2.177e-02	-3.83	cell proliferation in external granule layer	biological process	GO:0021924	8	1	18204	50	RORA
2.177e-02	-3.83	dermatan sulfate proteoglycan biosynthetic process	biological process	GO:0050651	8	1	18204	50	CSGALNACT1
2.177e-02	-3.83	regulation of L-glutamate import across plasma membrane	biological process	GO:0002036	8	1	18204	50	ATP1A2
2.177e-02	-3.83	cell proliferation in hindbrain	biological process	GO:0021534	8	1	18204	50	RORA
2.177e-02	-3.83	meiotic cytokinesis	biological process	GO:0033206	8	1	18204	50	FMN2
2.177e-02	-3.83	heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process	biological process	GO:0015014	8	1	18204	50	CSGALNACT1
2.177e-02	-3.83	gamma-aminobutyric acid metabolic process	biological process	GO:0009448	8	1	18204	50	SLC1A3
2.177e-02	-3.83	cerebellar granule cell precursor proliferation	biological process	GO:0021930	8	1	18204	50	RORA
2.177e-02	-3.83	insulin processing	biological process	GO:0030070	8	1	18204	50	CPE
2.182e-02	-3.82	Glyco_tran_10_N	pfam domains	PF17039	8	1	17795	49	FUT9
2.182e-02	-3.82	VHP	pfam domains	PF02209	8	1	17795	49	ABLIM1
2.182e-02	-3.82	CHGN	pfam domains	PF05679	8	1	17795	49	CSGALNACT1
2.182e-02	-3.82	Glyco_transf_10	pfam domains	PF00852	8	1	17795	49	FUT9
2.182e-02	-3.82	AC_N	pfam domains	PF16214	8	1	17795	49	ADCY2
2.184e-02	-3.82	regulation of amine transport	biological process	GO:0051952	83	2	18204	50	PRKG1,ATP1A2
2.184e-02	-3.82	positive regulation of MAP kinase activity	biological process	GO:0043406	83	2	18204	50	TPD52L1,SASH1
2.186e-02	-3.82	skin-upper_arm-malignant_melanoma	COSMIC cancer mutations	skin-upper_arm-malignant_melanoma	553	5	16828	49	ITPR2,PREX2,FUT9,FMN2,PARD3B
2.193e-02	-3.82	Platelet homeostasis	REACTOME pathways	R-HSA-418346	91	2	10285	26	PRKG1,ITPR2
2.199e-02	-3.82	SERPINB13 (serpin family B member 13)	protein interactions	5275	89	2	19454	50	CSGALNACT1,PPP2R2B
2.199e-02	-3.82	SOX10 (SRY-box transcription factor 10)	protein interactions	6663	89	2	19454	50	TRPS1,NFIA
2.221e-02	-3.81	sensory system development	biological process	GO:0048880	391	4	18204	50	GPM6A,NFIA,NTRK2,BMPR1B
2.224e-02	-3.81	HMG20A (high mobility group 20A)	protein interactions	10363	234	3	19454	50	NFIA,SOX5,DTNA
2.231e-02	-3.80	carbohydrate derivative biosynthetic process	biological process	GO:1901137	589	5	18204	50	BMPR1B,MGAT4C,FUT9,ADCY2,CSGALNACT1
2.233e-02	-3.80	proteoglycan metabolic process	biological process	GO:0006029	84	2	18204	50	BMPR1B,CSGALNACT1
2.233e-02	-3.80	L-amino acid transport	biological process	GO:0015807	84	2	18204	50	SLC1A3,SLC1A2
2.233e-02	-3.80	regulation of sodium ion transport	biological process	GO:0002028	84	2	18204	50	ATP1A2,NKAIN3
2.238e-02	-3.80	Post-translational modification: synthesis of GPI-anchored proteins	REACTOME pathways	R-HSA-163125	92	2	10285	26	LSAMP,NTM
2.245e-02	-3.80	Glycosyl transferase family 10, C-terminal domain	gene3d domains	3.40.50.11660	8	1	14470	41	FUT9
2.245e-02	-3.80	Villin headpiece domain	gene3d domains	1.10.950.10	8	1	14470	41	ABLIM1
2.246e-02	-3.80	CTDSPL (CTD small phosphatase like)	protein interactions	10217	90	2	19454	50	FMN2,DTNA
2.264e-02	-3.79	GAS2	smart domains	SM00243	6	1	9717	37	MACF1
2.264e-02	-3.79	LIM_DOMAIN_1	prosite domains	PS00478	71	2	12186	40	NEBL,ABLIM1
2.264e-02	-3.79	LIM_DOMAIN_2	prosite domains	PS50023	71	2	12186	40	ABLIM1,NEBL
2.272e-02	-3.78	human chr6q26	chromosome location	human chr6q26	12	1	26134	50	QKI
2.275e-02	-3.78	ACTIVIN2R	prints domains	PR00653	6	1	5227	20	BMPR1B
2.276e-02	-3.78	GS	prosite domains	PS51256	7	1	12186	40	BMPR1B
2.283e-02	-3.78	chondrocyte differentiation	biological process	GO:0002062	85	2	18204	50	SOX5,BMPR1B
2.283e-02	-3.78	oligodendrocyte differentiation	biological process	GO:0048709	85	2	18204	50	PTPRZ1,NTRK2
2.285e-02	-3.78	flotillin complex	cellular component	GO:0016600	9	1	19108	49	SORBS1
2.285e-02	-3.78	platelet dense tubular network membrane	cellular component	GO:0031095	9	1	19108	49	ITPR2
2.290e-02	-3.78	Ywhag (tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide)	protein interactions	22628	9	1	19454	50	QKI
2.290e-02	-3.78	NRXN2 (neurexin 2)	protein interactions	9379	9	1	19454	50	MACF1
2.290e-02	-3.78	Tyw3 (tRNA-yW synthesizing protein 3 homolog (S. cerevisiae))	protein interactions	209584	9	1	19454	50	CTNNA2
2.290e-02	-3.78	VEPH1 (ventricular zone expressed PH domain containing 1)	protein interactions	79674	9	1	19454	50	BMPR1B
2.290e-02	-3.78	PI3 (peptidase inhibitor 3)	protein interactions	5266	9	1	19454	50	PPP2R2B
2.290e-02	-3.78	IER5 (immediate early response 5)	protein interactions	51278	9	1	19454	50	PPP2R2B
2.292e-02	-3.78	DGUOK (deoxyguanosine kinase)	protein interactions	1716	91	2	19454	50	GPM6A,NTM
2.292e-02	-3.78	SOS1 (SOS Ras/Rac guanine nucleotide exchange factor 1)	protein interactions	6654	91	2	19454	50	TNIK,SORBS1
2.292e-02	-3.78	FOXI1 (forkhead box I1)	protein interactions	2299	91	2	19454	50	TRPS1,NFIA
2.299e-02	-3.77	CAMK2A (calcium/calmodulin dependent protein kinase II alpha)	protein interactions	815	237	3	19454	50	ITPR2,GPM6A,SOX5
2.306e-02	-3.77	central_nervous_system-chiasm-glioma-astrocytoma_Grade_I	COSMIC cancer mutations	central_nervous_system-chiasm-glioma-astrocytoma_Grade_I	8	1	16828	49	QKI
2.306e-02	-3.77	skin-chest-malignant_melanoma-nodular	COSMIC cancer mutations	skin-chest-malignant_melanoma-nodular	8	1	16828	49	PREX2
2.320e-02	-3.76	Intracellular Signalling Through Prostacyclin Receptor and Prostacyclin	SMPDB pathways	SMP0000354	8	1	1369	4	ADCY2
2.339e-02	-3.76	SOX9 (SRY-box transcription factor 9)	protein interactions	6662	92	2	19454	50	NFIA,TRPS1
2.346e-02	-3.75	response to oxygen-containing compound	biological process	GO:1901700	1546	9	18204	50	ZBTB20,RYR3,ATP1A2,ITPR2,SLC1A3,RORA,SLC1A2,SORBS1,ADCY2
2.352e-02	-3.75	cellular process involved in reproduction in multicellular organism	biological process	GO:0022412	398	4	18204	50	PRKG1,QKI,FMN2,BMPR1B
2.352e-02	-3.75	organic anion transport	biological process	GO:0015711	398	4	18204	50	SLC1A2,SFXN5,SLC1A3,NTRK2
2.387e-02	-3.74	ARHGEF6 (Rac/Cdc42 guanine nucleotide exchange factor 6)	protein interactions	9459	93	2	19454	50	BMPR1B,ABLIM1
2.387e-02	-3.74	TEX11 (testis expressed 11)	protein interactions	56159	93	2	19454	50	QKI,SOX5
2.387e-02	-3.74	DMRTB1 (DMRT like family B with proline rich C-terminal 1)	protein interactions	63948	93	2	19454	50	QKI,MSI2
2.387e-02	-3.74	MIR19B2 (microRNA 19b-2)	protein interactions	406981	93	2	19454	50	QKI,MSI2
2.387e-02	-3.74	LGALS7B (galectin 7B)	protein interactions	653499	93	2	19454	50	PPP2R2B,CSGALNACT1
2.404e-02	-3.73	DNA-bd_RFX	interpro domains	IPR003150	9	1	18521	50	RFX4
2.404e-02	-3.73	Activin_recp	interpro domains	IPR000472	9	1	18521	50	BMPR1B
2.404e-02	-3.73	Fol_N	interpro domains	IPR003645	9	1	18521	50	SPARCL1
2.435e-02	-3.72	FOXP4 (forkhead box P4)	protein interactions	116113	94	2	19454	50	SOX5,NFIA
2.435e-02	-3.72	WWC1 (WW and C2 domain containing 1)	protein interactions	23286	94	2	19454	50	ABLIM1,TNIK
2.435e-02	-3.72	QSER1 (glutamine and serine rich 1)	protein interactions	79832	94	2	19454	50	SOX5,NFIA
2.437e-02	-3.71	large_intestine-rectum	COSMIC cancer mutations	large_intestine-rectum	569	5	16828	49	FMN2,PRKG1,SASH1,ADCY2,TRPS1
2.438e-02	-3.71	postsynapse	cellular component	GO:0098794	646	5	19108	49	CTNND2,ATP1A2,GPM6A,NTRK2,TNIK
2.446e-02	-3.71	fucose catabolic process	biological process	GO:0019317	9	1	18204	50	FUT9
2.446e-02	-3.71	negative regulation of actin nucleation	biological process	GO:0051126	9	1	18204	50	CTNNA2
2.446e-02	-3.71	L-fucose metabolic process	biological process	GO:0042354	9	1	18204	50	FUT9
2.446e-02	-3.71	release of sequestered calcium ion into cytosol by sarcoplasmic reticulum	biological process	GO:0014808	9	1	18204	50	RYR3
2.446e-02	-3.71	hindbrain radial glia guided cell migration	biological process	GO:0021932	9	1	18204	50	CTNNA2
2.446e-02	-3.71	negative regulation of striated muscle contraction	biological process	GO:0045988	9	1	18204	50	ATP1A2
2.446e-02	-3.71	L-fucose catabolic process	biological process	GO:0042355	9	1	18204	50	FUT9
2.452e-02	-3.71	RFX_DNA_binding	pfam domains	PF02257	9	1	17795	49	RFX4
2.452e-02	-3.71	Activin_recp	pfam domains	PF01064	9	1	17795	49	BMPR1B
2.456e-02	-3.71	membrane	cellular component	GO:0016020	9220	31	19108	49	SFXN5,FMN2,PREX2,PRKG1,FUT9,DTNA,GPM6A,BMPR1B,CTNND2,NTM,MGAT4C,PTPRZ1,NKAIN3,NTRK2,LSAMP,CDH20,CPE,TNIK,GPC5,CTNNA2,MACF1,SLC1A3,ITPR2,ATP1A2,SORBS1,CSGALNACT1,PARD3B,PPP2R2B,ADCY2,SLC1A2,RYR3
2.459e-02	-3.71	human chr5p15.1	chromosome location	human chr5p15.1	13	1	26134	50	FBXL7
2.468e-02	-3.70	skeletal system morphogenesis	biological process	GO:0048705	228	3	18204	50	BMPR1B,SOX5,CSGALNACT1
2.487e-02	-3.69	positive regulation of lipid biosynthetic process	biological process	GO:0046889	89	2	18204	50	SORBS1,ZBTB20
2.495e-02	-3.69	axon	cellular component	GO:0030424	650	5	19108	49	DTNA,GPM6A,SLC1A2,NTRK2,CTNNA2
2.496e-02	-3.69	DNA-binding transcription factor activity, RNA polymerase II-specific	molecular function	GO:0000981	1355	8	18094	48	ZBTB20,RFX4,NPAS3,GLIS3,SOX5,RORA,TRPS1,NFIA
2.500e-02	-3.69	Adenylate cyclase activating pathway	REACTOME pathways	R-HSA-170660	10	1	10285	26	ADCY2
2.521e-02	-3.68	sarcoplasm	cellular component	GO:0016528	96	2	19108	49	ITPR2,RYR3
2.523e-02	-3.68	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-NK-T_cell_lymphoma	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-NK-T_cell_lymphoma	217	3	16828	49	MGAT4C,RFX4,DTNA
2.523e-02	-3.68	cation binding	molecular function	GO:0043169	4341	18	18094	48	ABLIM1,CSGALNACT1,DTNA,MACF1,RORA,CPE,GLIS3,ITPR2,BMPR1B,MGAT4C,ZBTB20,RYR3,SPARCL1,TRPS1,ATP1A2,ADCY2,SLC1A3,SLC1A2
2.524e-02	-3.68	Transmembrane transport of small molecules	REACTOME pathways	R-HSA-382551	677	5	10285	26	SLC1A2,SLC1A3,ATP1A2,RYR3,ADCY2
2.532e-02	-3.68	E7 (E7 protein)	protein interactions	1489369	96	2	19454	50	QKI,SASH1
2.536e-02	-3.67	perineuronal net	cellular component	GO:0072534	10	1	19108	49	PTPRZ1
2.537e-02	-3.67	HNRNPL (heterogeneous nuclear ribonucleoprotein L)	protein interactions	3191	1958	10	19454	50	PARD3B,ZBTB20,MACF1,ABLIM1,BMPR1B,NFIA,QKI,MSI2,TRPS1,DTNA
2.541e-02	-3.67	CALB2 (calbindin 2)	protein interactions	794	10	1	19454	50	GPM6A
2.541e-02	-3.67	GSG1 (germ cell associated 1)	protein interactions	83445	10	1	19454	50	PITPNC1
2.541e-02	-3.67	Vbp1 (von Hippel-Lindau binding protein 1)	protein interactions	22327	10	1	19454	50	ABLIM1
2.541e-02	-3.67	P2rx7 (purinergic receptor P2X 7)	protein interactions	29665	10	1	19454	50	PTPRZ1
2.541e-02	-3.67	SLC8A2 (solute carrier family 8 member A2)	protein interactions	6543	10	1	19454	50	GPM6A
2.541e-02	-3.67	Hsp90aa1 (heat shock protein 90, alpha (cytosolic), class A member 1)	protein interactions	15519	10	1	19454	50	QKI
2.541e-02	-3.67	Mrpl13 (mitochondrial ribosomal protein L13)	protein interactions	68537	10	1	19454	50	QKI
2.541e-02	-3.67	Smurf2 (SMAD specific E3 ubiquitin protein ligase 2)	protein interactions	66313	10	1	19454	50	GLIS3
2.541e-02	-3.67	DEFA1B (defensin alpha 1B)	protein interactions	728358	10	1	19454	50	PPP2R2B
2.541e-02	-3.67	SERPINB11 (serpin family B member 11)	protein interactions	89778	10	1	19454	50	CPE
2.541e-02	-3.67	BANK1 (B cell scaffold protein with ankyrin repeats 1)	protein interactions	55024	10	1	19454	50	ITPR2
2.568e-02	-3.66	spindle	COSMIC cancer mutations	spindle	386	4	16828	49	CTNND2,CPE,MACF1,PREX2
2.570e-02	-3.66	PROKAR_LIPOPROTEIN	prosite domains	PS51257	76	2	12186	40	CPE,GLIS3
2.580e-02	-3.66	Aldosterone synthesis and secretion	KEGG pathways	ko04925	82	2	7161	22	ADCY2,ITPR2
2.580e-02	-3.66	Aldosterone synthesis and secretion	KEGG pathways	hsa04925	82	2	7161	22	ITPR2,ADCY2
2.585e-02	-3.66	NCOR2 (nuclear receptor corepressor 2)	protein interactions	9612	248	3	19454	50	NFIA,SOX5,TNIK
2.591e-02	-3.65	skin-chest-malignant_melanoma-superficial_spreading	COSMIC cancer mutations	skin-chest-malignant_melanoma-superficial_spreading	9	1	16828	49	PREX2
2.591e-02	-3.65	skin-upper_leg-malignant_melanoma-superficial_spreading	COSMIC cancer mutations	skin-upper_leg-malignant_melanoma-superficial_spreading	9	1	16828	49	PREX2
2.592e-02	-3.65	response to BMP	biological process	GO:0071772	91	2	18204	50	NFIA,BMPR1B
2.592e-02	-3.65	cellular response to BMP stimulus	biological process	GO:0071773	91	2	18204	50	NFIA,BMPR1B
2.597e-02	-3.65	GATA_ZN_FINGER_1	prosite domains	PS00344	8	1	12186	40	TRPS1
2.597e-02	-3.65	HP	prosite domains	PS51089	8	1	12186	40	ABLIM1
2.607e-02	-3.65	Excitatory Neural Signalling Through 5-HTR 7 and Serotonin	SMPDB pathways	SMP0000311	9	1	1369	4	ADCY2
2.607e-02	-3.65	Intracellular Signalling Through Histamine H2 Receptor and Histamine	SMPDB pathways	SMP0000335	9	1	1369	4	ADCY2
2.607e-02	-3.65	Excitatory Neural Signalling Through 5-HTR 6 and Serotonin	SMPDB pathways	SMP0000312	9	1	1369	4	ADCY2
2.607e-02	-3.65	Excitatory Neural Signalling Through 5-HTR 4 and Serotonin	SMPDB pathways	SMP0000309	9	1	1369	4	ADCY2
2.607e-02	-3.65	Intracellular Signalling Through FSH Receptor and Follicle Stimulating Hormone	SMPDB pathways	SMP0000333	9	1	1369	4	ADCY2
2.612e-02	-3.65	transmembrane transporter activity	molecular function	GO:0022857	1110	7	18094	48	RYR3,ITPR2,SLC1A3,GPM6A,ATP1A2,SFXN5,SLC1A2
2.621e-02	-3.64	oesophagus-carcinoma-adenocarcinoma	COSMIC cancer mutations	oesophagus-carcinoma-adenocarcinoma	13112	44	16828	49	CDH20,RFX4,PPP2R2B,NHSL1,SORBS1,SPARCL1,RYR3,SOX5,PARD3B,SFXN5,FMN2,GPC5,GLIS3,ADCY2,FBXL7,NPAS3,PREX2,ITPR2,SLC1A2,FUT9,MGAT4C,TPD52L1,MAML2,TRPS1,LSAMP,QKI,GPM6A,BMPR1B,SLC1A3,NEBL,CSGALNACT1,NKAIN3,PTPRZ1,NTM,SASH1,NTRK2,CTNND2,ZBTB20,MACF1,RORA,PRKG1,TNIK,CPE,ATP1A2
2.622e-02	-3.64	phosphatidylinositol transfer activity	molecular function	GO:0008526	10	1	18094	48	PITPNC1
2.622e-02	-3.64	neurotrophin binding	molecular function	GO:0043121	10	1	18094	48	NTRK2
2.631e-02	-3.64	MED27 (mediator complex subunit 27)	protein interactions	9442	98	2	19454	50	SOX5,QKI
2.631e-02	-3.64	FRS2 (fibroblast growth factor receptor substrate 2)	protein interactions	10818	98	2	19454	50	NTRK2,SORBS1
2.631e-02	-3.64	DNAAF2 (dynein axonemal assembly factor 2)	protein interactions	55172	98	2	19454	50	LSAMP,GPM6A
2.636e-02	-3.64	GS	smart domains	SM00467	7	1	9717	37	BMPR1B
2.636e-02	-3.64	PLEC	smart domains	SM00250	7	1	9717	37	MACF1
2.640e-02	-3.63	mannosyl-glycoprotein N-acetylglucosaminyltransferases	BIOCYC pathways	META_PWY-7426	8	1	902	3	MGAT4C
2.640e-02	-3.63	terminal O-glycans residues modification	BIOCYC pathways	HUMAN_PWY-7434	8	1	902	3	FUT9
2.646e-02	-3.63	human chr6q16.1	chromosome location	human chr6q16.1	14	1	26134	50	FUT9
2.646e-02	-3.63	human chr2p13.2	chromosome location	human chr2p13.2	14	1	26134	50	SFXN5
2.654e-02	-3.63	upper_arm	COSMIC cancer mutations	upper_arm	582	5	16828	49	FUT9,PREX2,ITPR2,FMN2,PARD3B
2.666e-02	-3.62	TGFBR1 (transforming growth factor beta receptor 1)	protein interactions	7046	251	3	19454	50	BMPR1B,PREX2,PPP2R2B
2.666e-02	-3.62	Ig_sub2	interpro domains	IPR003598	239	3	18521	50	NTRK2,NTM,LSAMP
2.668e-02	-3.62	PAS_fold_3	interpro domains	IPR013655	10	1	18521	50	NPAS3
2.676e-02	-3.62	inorganic cation transmembrane transport	biological process	GO:0098662	618	5	18204	50	GPM6A,SLC1A3,RYR3,ATP1A2,ITPR2
2.680e-02	-3.62	ZFHX3 (zinc finger homeobox 3)	protein interactions	463	99	2	19454	50	SOX5,TRPS1
2.693e-02	-3.61	CRX (cone-rod homeobox)	protein interactions	1406	252	3	19454	50	NFIA,SOX5,TRPS1
2.701e-02	-3.61	anchoring junction	cellular component	GO:0070161	902	6	19108	49	PARD3B,CTNNA2,SORBS1,CDH20,ATP1A2,CTNND2
2.714e-02	-3.61	retinal rod cell development	biological process	GO:0046548	10	1	18204	50	NTRK2
2.714e-02	-3.61	trans-synaptic signaling, modulating synaptic transmission	biological process	GO:0099550	10	1	18204	50	NTRK2
2.714e-02	-3.61	regulation of mesenchymal stem cell differentiation	biological process	GO:2000739	10	1	18204	50	SOX5
2.714e-02	-3.61	somatic stem cell division	biological process	GO:0048103	10	1	18204	50	FUT9
2.714e-02	-3.61	establishment of centrosome localization	biological process	GO:0051660	10	1	18204	50	PARD3B
2.714e-02	-3.61	positive regulation of lipopolysaccharide-mediated signaling pathway	biological process	GO:0031666	10	1	18204	50	SASH1
2.714e-02	-3.61	cellular response to brain-derived neurotrophic factor stimulus	biological process	GO:1990416	10	1	18204	50	NTRK2
2.714e-02	-3.61	cAMP biosynthetic process	biological process	GO:0006171	10	1	18204	50	ADCY2
2.714e-02	-3.61	release of sequestered calcium ion into cytosol by endoplasmic reticulum	biological process	GO:1903514	10	1	18204	50	RYR3
2.720e-02	-3.60	PAS_3	pfam domains	PF08447	10	1	17795	49	NPAS3
2.731e-02	-3.60	ATP4A (ATPase H+/K+ transporting subunit alpha)	protein interactions	495	100	2	19454	50	ATP1A2,GPM6A
2.733e-02	-3.60	cGMP signaling	KEGG pathways	M00694	9	1	7161	22	PRKG1
2.733e-02	-3.60	cGMP signaling	KEGG pathways	hsa_M00694	9	1	7161	22	PRKG1
2.741e-02	-3.60	uveal_tract	COSMIC cancer mutations	uveal_tract	587	5	16828	49	MACF1,PREX2,ADCY2,CTNND2,CPE
2.756e-02	-3.59	muscle contraction	biological process	GO:0006936	238	3	18204	50	ATP1A2,DTNA,RYR3
2.758e-02	-3.59	Insulin secretion	KEGG pathways	hsa04911	85	2	7161	22	ADCY2,ATP1A2
2.769e-02	-3.59	NK-T_cell_lymphoma	COSMIC cancer mutations	NK-T_cell_lymphoma	225	3	16828	49	MGAT4C,RFX4,DTNA
2.776e-02	-3.58	DYNLL2 (dynein light chain LC8-type 2)	protein interactions	140735	255	3	19454	50	TRPS1,NFIA,NHSL1
2.781e-02	-3.58	EVPL (envoplakin)	protein interactions	2125	101	2	19454	50	PPP2R2B,NKAIN3
2.786e-02	-3.58	platelet dense tubular network	cellular component	GO:0031094	11	1	19108	49	ITPR2
2.786e-02	-3.58	perisynaptic extracellular matrix	cellular component	GO:0098966	11	1	19108	49	PTPRZ1
2.792e-02	-3.58	AQP5 (aquaporin 5)	protein interactions	362	11	1	19454	50	ATP1A2
2.792e-02	-3.58	DAZ1 (deleted in azoospermia 1)	protein interactions	1617	11	1	19454	50	QKI
2.792e-02	-3.58	Wipi2 (WD repeat domain, phosphoinositide interacting 2)	protein interactions	74781	11	1	19454	50	MACF1
2.792e-02	-3.58	ADCY5 (adenylate cyclase 5)	protein interactions	111	11	1	19454	50	ADCY2
2.792e-02	-3.58	Batf3 (basic leucine zipper transcription factor, ATF-like 3)	protein interactions	381319	11	1	19454	50	MACF1
2.792e-02	-3.58	NTS (neurotensin)	protein interactions	4922	11	1	19454	50	CPE
2.792e-02	-3.58	Gtf2e2 (general transcription factor II E, polypeptide 2 (beta subunit))	protein interactions	68153	11	1	19454	50	NHSL1
2.792e-02	-3.58	IL7 (interleukin 7)	protein interactions	3574	11	1	19454	50	QKI
2.792e-02	-3.58	SYN3 (synapsin III)	protein interactions	8224	11	1	19454	50	GPM6A
2.792e-02	-3.58	Cobll1 (Cobl-like 1)	protein interactions	319876	11	1	19454	50	ABLIM1
2.795e-02	-3.58	axon development	biological process	GO:0061564	420	4	18204	50	PTPRZ1,PRKG1,BMPR1B,CTNNA2
2.802e-02	-3.58	RNA polymerase II transcription regulatory region sequence-specific DNA binding	molecular function	GO:0000977	1385	8	18094	48	RFX4,RORA,ZBTB20,NPAS3,TRPS1,NFIA,SOX5,GLIS3
2.807e-02	-3.57	cardiac muscle cell differentiation	biological process	GO:0055007	95	2	18204	50	PRKG1,NEBL
2.807e-02	-3.57	calcium ion transmembrane import into cytosol	biological process	GO:0097553	95	2	18204	50	ITPR2,RYR3
2.832e-02	-3.56	human chr8q12.3	chromosome location	human chr8q12.3	15	1	26134	50	NKAIN3
2.832e-02	-3.56	human chr10p12.31	chromosome location	human chr10p12.31	15	1	26134	50	NEBL
2.832e-02	-3.56	MIR7-1 (microRNA 7-1)	protein interactions	407043	102	2	19454	50	MSI2,QKI
2.875e-02	-3.55	skin-back-malignant_melanoma-nodular	COSMIC cancer mutations	skin-back-malignant_melanoma-nodular	10	1	16828	49	PREX2
2.875e-02	-3.55	chiasm	COSMIC cancer mutations	chiasm	10	1	16828	49	QKI
2.876e-02	-3.55	metal ion transport	biological process	GO:0030001	630	5	18204	50	SLC1A3,GPM6A,ITPR2,ATP1A2,RYR3
2.880e-02	-3.55	sulfur amino acid transmembrane transporter activity	molecular function	GO:0000099	11	1	18094	48	SLC1A2
2.881e-02	-3.55	upper_aerodigestive_tract-head_neck-carcinoma-squamous_cell_carcinoma	COSMIC cancer mutations	upper_aerodigestive_tract-head_neck-carcinoma-squamous_cell_carcinoma	9263	34	16828	49	SORBS1,RYR3,QKI,PPP2R2B,BMPR1B,NHSL1,NFIA,TRPS1,LSAMP,PITPNC1,CDH20,MGAT4C,MAML2,ITPR2,ATP1A2,FBXL7,ADCY2,PREX2,MACF1,RORA,PRKG1,TNIK,MSI2,NKAIN3,PTPRZ1,NTRK2,SASH1,GPC5,GLIS3,CTNND2,SOX5,NEBL,PARD3B,FMN2
2.884e-02	-3.55	CSGALNACT2 (chondroitin sulfate N-acetylgalactosaminyltransferase 2)	protein interactions	55454	103	2	19454	50	CSGALNACT1,MGAT4C
2.884e-02	-3.55	RAB6B (RAB6B, member RAS oncogene family)	protein interactions	51560	103	2	19454	50	BMPR1B,GPM6A
2.889e-02	-3.54	MARK2 (microtubule affinity regulating kinase 2)	protein interactions	2011	259	3	19454	50	PPP2R2B,DTNA,PARD3B
2.893e-02	-3.54	amino acid transmembrane transporter activity	molecular function	GO:0015171	100	2	18094	48	SLC1A3,SLC1A2
2.893e-02	-3.54	Intracellular Signalling Through LHCGR Receptor and Luteinizing Hormone/Choriogonadotropin	SMPDB pathways	SMP0000338	10	1	1369	4	ADCY2
2.917e-02	-3.53	RFX_DBD	prosite domains	PS51526	9	1	12186	40	RFX4
2.917e-02	-3.53	positive regulation of JNK cascade	biological process	GO:0046330	97	2	18204	50	TPD52L1,TNIK
2.917e-02	-3.53	amino acid transmembrane transport	biological process	GO:0003333	97	2	18204	50	SLC1A2,SLC1A3
2.920e-02	-3.53	LCK (LCK proto-oncogene, Src family tyrosine kinase)	protein interactions	3932	455	4	19454	50	DTNA,FMN2,CTNND2,MACF1
2.931e-02	-3.53	Tyr_kinase_rcpt_2_CS	interpro domains	IPR002011	11	1	18521	50	NTRK2
2.946e-02	-3.52	DIRAS3 (DIRAS family GTPase 3)	protein interactions	9077	261	3	19454	50	MACF1,FMN2,DTNA
2.963e-02	-3.52	Transport of inorganic cations/anions and amino acids/oligopeptides	REACTOME pathways	R-HSA-425393	107	2	10285	26	SLC1A3,SLC1A2
2.972e-02	-3.52	kidney-carcinoma	COSMIC cancer mutations	kidney-carcinoma	3720	17	16828	49	MAML2,PITPNC1,SOX5,CTNND2,TRPS1,PTPRZ1,NTRK2,PRKG1,PPP2R2B,MSI2,TNIK,BMPR1B,FBXL7,QKI,RORA,PREX2,ITPR2
2.974e-02	-3.52	LIM	smart domains	SM00132	71	2	9717	37	ABLIM1,NEBL
2.980e-02	-3.51	monoatomic cation transmembrane transport	biological process	GO:0098655	636	5	18204	50	SLC1A3,GPM6A,ATP1A2,RYR3,ITPR2
2.981e-02	-3.51	intracellular mRNA localization	biological process	GO:0008298	11	1	18204	50	QKI
2.981e-02	-3.51	lactone metabolic process	biological process	GO:1901334	11	1	18204	50	ATP1A2
2.981e-02	-3.51	negative regulation of platelet aggregation	biological process	GO:0090331	11	1	18204	50	PRKG1
2.981e-02	-3.51	cell growth involved in cardiac muscle cell development	biological process	GO:0061049	11	1	18204	50	PRKG1
2.981e-02	-3.51	physiological cardiac muscle hypertrophy	biological process	GO:0003301	11	1	18204	50	PRKG1
2.981e-02	-3.51	glutamate secretion	biological process	GO:0014047	11	1	18204	50	NTRK2
2.981e-02	-3.51	establishment or maintenance of transmembrane electrochemical gradient	biological process	GO:0010248	11	1	18204	50	ATP1A2
2.981e-02	-3.51	physiological muscle hypertrophy	biological process	GO:0003298	11	1	18204	50	PRKG1
2.981e-02	-3.51	heparin biosynthetic process	biological process	GO:0030210	11	1	18204	50	CSGALNACT1
2.981e-02	-3.51	cellular response to caffeine	biological process	GO:0071313	11	1	18204	50	RYR3
2.981e-02	-3.51	antral ovarian follicle growth	biological process	GO:0001547	11	1	18204	50	BMPR1B
2.981e-02	-3.51	L-ascorbic acid metabolic process	biological process	GO:0019852	11	1	18204	50	ATP1A2
2.981e-02	-3.51	PPP2CA (protein phosphatase 2 catalytic subunit alpha)	protein interactions	5515	458	4	19454	50	NHSL1,CSGALNACT1,BMPR1B,PPP2R2B
2.984e-02	-3.51	cell motility	biological process	GO:0048870	1101	7	18204	50	GPC5,PRKG1,FMN2,CDH20,CTNNA2,GPM6A,NTRK2
2.988e-02	-3.51	BEND3 (BEN domain containing 3)	protein interactions	57673	105	2	19454	50	TRPS1,TNIK
2.993e-02	-3.51	Defective EXT1 causes exostoses 1, TRPS2 and CHDS	REACTOME pathways	R-HSA-3656253	12	1	10285	26	GPC5
2.993e-02	-3.51	Defective EXT2 causes exostoses 2	REACTOME pathways	R-HSA-3656237	12	1	10285	26	GPC5
2.999e-02	-3.51	regulation of synapse organization	biological process	GO:0050807	246	3	18204	50	GPM6A,NTRK2,CTNNA2
3.007e-02	-3.50	VHP	smart domains	SM00153	8	1	9717	37	ABLIM1
3.022e-02	-3.50	GATAZNFINGER	prints domains	PR00619	8	1	5227	20	TRPS1
3.028e-02	-3.50	bone morphogenesis	biological process	GO:0060349	99	2	18204	50	CSGALNACT1,BMPR1B
3.030e-02	-3.50	abdomen	COSMIC cancer mutations	abdomen	603	5	16828	49	FUT9,ITPR2,PREX2,FMN2,CTNND2
3.034e-02	-3.50	trans-synaptic signaling	biological process	GO:0099537	431	4	18204	50	SLC1A3,NTRK2,DTNA,SLC1A2
3.034e-02	-3.50	response to wounding	biological process	GO:0009611	431	4	18204	50	MACF1,SLC1A2,NFIA,SLC1A3
3.035e-02	-3.49	sodium:potassium-exchanging ATPase complex	cellular component	GO:0005890	12	1	19108	49	ATP1A2
3.035e-02	-3.49	synapse-associated extracellular matrix	cellular component	GO:0099535	12	1	19108	49	PTPRZ1
3.042e-02	-3.49	LMP-1 (latent membrane protein LMP-1)	protein interactions	3783750	12	1	19454	50	TNIK
3.042e-02	-3.49	NTF4 (neurotrophin 4)	protein interactions	4909	12	1	19454	50	NTRK2
3.042e-02	-3.49	BAMBI (BMP and activin membrane bound inhibitor)	protein interactions	25805	12	1	19454	50	BMPR1B
3.042e-02	-3.49	ART4 (ADP-ribosyltransferase 4 (inactive) (Dombrock blood group))	protein interactions	420	12	1	19454	50	GPM6A
3.042e-02	-3.49	PROK2 (prokineticin 2)	protein interactions	60675	12	1	19454	50	CPE
3.074e-02	-3.48	Carboxypeptidase-like, regulatory domain	gene3d domains	2.60.40.1120	11	1	14470	41	CPE
3.087e-02	-3.48	eye	COSMIC cancer mutations	eye	606	5	16828	49	CPE,CTNND2,ADCY2,MACF1,PREX2
3.107e-02	-3.47	MCAM (melanoma cell adhesion molecule)	protein interactions	4162	464	4	19454	50	SASH1,TNIK,CTNNA2,PARD3B
3.129e-02	-3.46	mRNA surveillance pathway	KEGG pathways	ko03015	91	2	7161	22	PPP2R2B,MSI2
3.129e-02	-3.46	mRNA surveillance pathway	KEGG pathways	hsa03015	91	2	7161	22	PPP2R2B,MSI2
3.138e-02	-3.46	inositol 1,4,5 trisphosphate binding	molecular function	GO:0070679	12	1	18094	48	ITPR2
3.138e-02	-3.46	adenylate cyclase binding	molecular function	GO:0008179	12	1	18094	48	ADCY2
3.142e-02	-3.46	regulation of glucose metabolic process	biological process	GO:0010906	101	2	18204	50	RORA,SORBS1
3.142e-02	-3.46	regulation of carbohydrate biosynthetic process	biological process	GO:0043255	101	2	18204	50	SORBS1,PRKG1
3.147e-02	-3.46	EN1 (engrailed homeobox 1)	protein interactions	2019	108	2	19454	50	TRPS1,NFIA
3.147e-02	-3.46	FKBP1A (FKBP prolyl isomerase 1A)	protein interactions	2280	108	2	19454	50	MSI2,RYR3
3.147e-02	-3.46	PAX8 (paired box 8)	protein interactions	7849	108	2	19454	50	TRPS1,NFIA
3.147e-02	-3.46	DSG4 (desmoglein 4)	protein interactions	147409	108	2	19454	50	SPARCL1,CSGALNACT1
3.149e-02	-3.46	PFN1 (profilin 1)	protein interactions	5216	466	4	19454	50	FMN2,NHSL1,MACF1,ABLIM1
3.151e-02	-3.46	VCL (vinculin)	protein interactions	7414	268	3	19454	50	SORBS1,MACF1,NEBL
3.157e-02	-3.46	calcium ion transport	biological process	GO:0006816	251	3	18204	50	GPM6A,ITPR2,RYR3
3.158e-02	-3.46	skin-back-malignant_melanoma-superficial_spreading	COSMIC cancer mutations	skin-back-malignant_melanoma-superficial_spreading	11	1	16828	49	PREX2
3.158e-02	-3.46	skin-hand-malignant_melanoma-acral_lentiginous	COSMIC cancer mutations	skin-hand-malignant_melanoma-acral_lentiginous	11	1	16828	49	PREX2
3.170e-02	-3.45	Integration of energy metabolism	REACTOME pathways	R-HSA-163685	111	2	10285	26	ADCY2,ITPR2
3.179e-02	-3.45	NAD+ Signalling and Aging	SMPDB pathways	SMP0084271	11	1	1369	4	RORA
3.189e-02	-3.45	regulation of synapse structure or activity	biological process	GO:0050803	252	3	18204	50	CTNNA2,GPM6A,NTRK2
3.192e-02	-3.44	GnRH signaling pathway	KEGG pathways	hsa04912	92	2	7161	22	ITPR2,ADCY2
3.192e-02	-3.44	GnRH signaling pathway	KEGG pathways	ko04912	92	2	7161	22	ITPR2,ADCY2
3.193e-02	-3.44	TGFB_receptor	interpro domains	IPR000333	12	1	18521	50	BMPR1B
3.193e-02	-3.44	MAD_homology1_Dwarfin-type	interpro domains	IPR003619	12	1	18521	50	NFIA
3.200e-02	-3.44	CLSTN1 (calsyntenin 1)	protein interactions	22883	109	2	19454	50	SLC1A3,MGAT4C
3.200e-02	-3.44	MIR34B (microRNA 34b)	protein interactions	407041	109	2	19454	50	QKI,MSI2
3.204e-02	-3.44	human chr9q21.33	chromosome location	human chr9q21.33	17	1	26134	50	NTRK2
3.207e-02	-3.44	biliary_tract-bile_duct-carcinoma-adenocarcinoma	COSMIC cancer mutations	biliary_tract-bile_duct-carcinoma-adenocarcinoma	15095	48	16828	49	CSGALNACT1,NEBL,SASH1,NTRK2,NTM,DTNA,PTPRZ1,CTNND2,MACF1,RORA,ZBTB20,TNIK,PRKG1,ATP1A2,CPE,FUT9,MGAT4C,TPD52L1,MAML2,TRPS1,LSAMP,QKI,BMPR1B,NFIA,GPM6A,SLC1A3,SOX5,SFXN5,FMN2,PARD3B,GLIS3,GPC5,ABLIM1,PREX2,FBXL7,NPAS3,ADCY2,MSI2,ITPR2,SLC1A2,CDH20,PITPNC1,RFX4,NHSL1,PPP2R2B,SORBS1,RYR3,SPARCL1
3.207e-02	-3.44	bile_duct	COSMIC cancer mutations	bile_duct	15095	48	16828	49	LSAMP,TRPS1,MAML2,TPD52L1,FUT9,MGAT4C,SLC1A3,GPM6A,NFIA,BMPR1B,QKI,CTNND2,PTPRZ1,DTNA,NTM,NTRK2,SASH1,NEBL,CSGALNACT1,ATP1A2,CPE,PRKG1,TNIK,ZBTB20,RORA,MACF1,RFX4,PITPNC1,CDH20,SPARCL1,RYR3,SORBS1,PPP2R2B,NHSL1,GPC5,GLIS3,PARD3B,SFXN5,FMN2,SOX5,SLC1A2,ITPR2,MSI2,FBXL7,NPAS3,ADCY2,ABLIM1,PREX2
3.239e-02	-3.43	CLEC7A (Dectin-1) induces NFAT activation	REACTOME pathways	R-HSA-5607763	13	1	10285	26	ITPR2
3.239e-02	-3.43	NOTCH2 intracellular domain regulates transcription	REACTOME pathways	R-HSA-2197563	13	1	10285	26	MAML2
3.239e-02	-3.43	Notch-HLH transcription pathway	REACTOME pathways	R-HSA-350054	13	1	10285	26	MAML2
3.248e-02	-3.43	sulfur amino acid transport	biological process	GO:0000101	12	1	18204	50	SLC1A2
3.248e-02	-3.43	dermatan sulfate proteoglycan metabolic process	biological process	GO:0050655	12	1	18204	50	CSGALNACT1
3.248e-02	-3.43	negative regulation of smooth muscle contraction	biological process	GO:0045986	12	1	18204	50	PRKG1
3.248e-02	-3.43	microglia differentiation	biological process	GO:0014004	12	1	18204	50	QKI
3.248e-02	-3.43	mammalian oogenesis stage	biological process	GO:0022605	12	1	18204	50	BMPR1B
3.248e-02	-3.43	positive regulation of extrinsic apoptotic signaling pathway via death domain receptors	biological process	GO:1902043	12	1	18204	50	BMPR1B
3.248e-02	-3.43	auditory behavior	biological process	GO:0031223	12	1	18204	50	SLC1A3
3.250e-02	-3.43	DNA-binding transcription repressor activity, RNA polymerase II-specific	molecular function	GO:0001227	263	3	18094	48	GLIS3,TRPS1,ZBTB20
3.254e-02	-3.43	LZTR1 (leucine zipper like post translational regulator 1)	protein interactions	8216	110	2	19454	50	PARD3B,BMPR1B
3.256e-02	-3.42	MH1	pfam domains	PF03165	12	1	17795	49	NFIA
3.256e-02	-3.42	CarboxypepD_reg	pfam domains	PF13620	12	1	17795	49	CPE
3.257e-02	-3.42	cerebellum development	biological process	GO:0021549	103	2	18204	50	RORA,PRKG1
3.271e-02	-3.42	RDX (radixin)	protein interactions	5962	272	3	19454	50	MACF1,ABLIM1,NEBL
3.276e-02	-3.42	steroid binding	molecular function	GO:0005496	107	2	18094	48	RORA,ATP1A2
3.291e-02	-3.41	PCDHA2 (protocadherin alpha 2)	protein interactions	56146	13	1	19454	50	NFIA
3.291e-02	-3.41	RAB3C (RAB3C, member RAS oncogene family)	protein interactions	115827	13	1	19454	50	GPM6A
3.291e-02	-3.41	SPINK5 (serine peptidase inhibitor Kazal type 5)	protein interactions	11005	13	1	19454	50	CSGALNACT1
3.291e-02	-3.41	TBCC (tubulin folding cofactor C)	protein interactions	6903	13	1	19454	50	NTM
3.291e-02	-3.41	Rbm47 (RNA binding motif protein 47)	protein interactions	245945	13	1	19454	50	QKI
3.315e-02	-3.41	regulation of steroid metabolic process	biological process	GO:0019218	104	2	18204	50	RORA,PRKG1
3.316e-02	-3.41	EF_HAND_2	prosite domains	PS50222	215	3	12186	40	SPARCL1,RYR3,MACF1
3.349e-02	-3.40	Alpha-catenin/vinculin-like	gene3d domains	1.20.120.230	12	1	14470	41	CTNNA2
3.363e-02	-3.39	HMGCS1 (3-hydroxy-3-methylglutaryl-CoA synthase 1)	protein interactions	3157	112	2	19454	50	PPP2R2B,GPM6A
3.363e-02	-3.39	CEP170P1 (centrosomal protein 170 pseudogene 1)	protein interactions	645455	112	2	19454	50	TRPS1,MACF1
3.373e-02	-3.39	cellular response to alcohol	biological process	GO:0097306	105	2	18204	50	ITPR2,ADCY2
3.377e-02	-3.39	FOLN	smart domains	SM00274	9	1	9717	37	SPARCL1
3.387e-02	-3.39	skin-arm-malignant_melanoma	COSMIC cancer mutations	skin-arm-malignant_melanoma	1308	8	16828	49	NPAS3,ZBTB20,MACF1,PARD3B,SORBS1,TRPS1,NTM,ATP1A2
3.389e-02	-3.38	human chr18q21.33	chromosome location	human chr18q21.33	18	1	26134	50	CDH20
3.389e-02	-3.38	human chr7q31.32	chromosome location	human chr7q31.32	18	1	26134	50	PTPRZ1
3.394e-02	-3.38	NAKATPASE	prints domains	PR00121	9	1	5227	20	ATP1A2
3.395e-02	-3.38	fucosyltransferase activity	molecular function	GO:0008417	13	1	18094	48	FUT9
3.395e-02	-3.38	potassium ion binding	molecular function	GO:0030955	13	1	18094	48	ATP1A2
3.395e-02	-3.38	transforming growth factor beta receptor activity	molecular function	GO:0005024	13	1	18094	48	BMPR1B
3.408e-02	-3.38	organic anion transmembrane transporter activity	molecular function	GO:0008514	268	3	18094	48	SLC1A2,SFXN5,SLC1A3
3.427e-02	-3.37	adrenal_gland	COSMIC cancer mutations	adrenal_gland	2628	13	16828	49	NTRK2,PTPRZ1,RFX4,CTNND2,SOX5,MAML2,CSGALNACT1,FMN2,SLC1A2,ATP1A2,ZBTB20,ADCY2,NHSL1
3.432e-02	-3.37	PROTEIN_KINASE_ATP	prosite domains	PS00107	377	4	12186	40	PRKG1,NTRK2,BMPR1B,TNIK
3.432e-02	-3.37	oogenesis	biological process	GO:0048477	106	2	18204	50	FMN2,BMPR1B
3.439e-02	-3.37	ear	COSMIC cancer mutations	ear	624	5	16828	49	SPARCL1,PRKG1,MGAT4C,NPAS3,ZBTB20
3.440e-02	-3.37	skin-abdomen-malignant_melanoma-nodular	COSMIC cancer mutations	skin-abdomen-malignant_melanoma-nodular	12	1	16828	49	PREX2
3.440e-02	-3.37	central_nervous_system-fourth_ventricle-glioma-astrocytoma_Grade_I	COSMIC cancer mutations	central_nervous_system-fourth_ventricle-glioma-astrocytoma_Grade_I	12	1	16828	49	QKI
3.440e-02	-3.37	DNA-binding transcription factor activity	molecular function	GO:0003700	1441	8	18094	48	TRPS1,RORA,NFIA,NPAS3,RFX4,ZBTB20,SOX5,GLIS3
3.459e-02	-3.36	plasma membrane raft	cellular component	GO:0044853	114	2	19108	49	ATP1A2,SORBS1
3.464e-02	-3.36	Lactose Degradation	SMPDB pathways	SMP0000457	12	1	1369	4	ATP1A2
3.464e-02	-3.36	Lactose Intolerance	SMPDB pathways	SMP0000458	12	1	1369	4	ATP1A2
3.474e-02	-3.36	ORF3b (ORF3b protein)	protein interactions	1489670	114	2	19454	50	ZBTB20,MACF1
3.484e-02	-3.36	DCC mediated attractive signaling	REACTOME pathways	R-HSA-418885	14	1	10285	26	ABLIM1
3.500e-02	-3.35	Ion_trans_dom	interpro domains	IPR005821	109	2	18521	50	ITPR2,RYR3
3.514e-02	-3.35	glial cell fate commitment	biological process	GO:0021781	13	1	18204	50	NFIA
3.514e-02	-3.35	cerebellar Purkinje cell differentiation	biological process	GO:0021702	13	1	18204	50	RORA
3.514e-02	-3.35	regulation of respiratory gaseous exchange by nervous system process	biological process	GO:0002087	13	1	18204	50	ATP1A2
3.514e-02	-3.35	negative regulation of cytosolic calcium ion concentration	biological process	GO:0051481	13	1	18204	50	ATP1A2
3.514e-02	-3.35	negative regulation of homotypic cell-cell adhesion	biological process	GO:0034111	13	1	18204	50	PRKG1
3.514e-02	-3.35	prepulse inhibition	biological process	GO:0060134	13	1	18204	50	CTNNA2
3.514e-02	-3.35	T-helper 17 cell differentiation	biological process	GO:0072539	13	1	18204	50	RORA
3.518e-02	-3.35	Inflammatory mediator regulation of TRP channels	KEGG pathways	hsa04750	97	2	7161	22	ITPR2,ADCY2
3.518e-02	-3.35	Inflammatory mediator regulation of TRP channels	KEGG pathways	ko04750	97	2	7161	22	ITPR2,ADCY2
3.529e-02	-3.34	cellular component organization	biological process	GO:0016043	5636	22	18204	50	CSGALNACT1,PARD3B,SLC1A2,ABLIM1,CTNNA2,TNIK,PTPRZ1,CTNND2,NEBL,MACF1,SPARCL1,BMPR1B,CDH20,SORBS1,RFX4,GPM6A,NFIA,PITPNC1,RYR3,PRKG1,PREX2,FMN2
3.530e-02	-3.34	TBXT (T-box transcription factor T)	protein interactions	6862	115	2	19454	50	NFIA,TRPS1
3.530e-02	-3.34	SMAD7 (SMAD family member 7)	protein interactions	4092	115	2	19454	50	SOX5,BMPR1B
3.538e-02	-3.34	DNA-binding transcription repressor activity	molecular function	GO:0001217	272	3	18094	48	GLIS3,TRPS1,ZBTB20
3.540e-02	-3.34	JMJD7-PLA2G4B (JMJD7-PLA2G4B readthrough)	protein interactions	8681	14	1	19454	50	PPP2R2B
3.540e-02	-3.34	RHEBL1 (RHEB like 1)	protein interactions	121268	14	1	19454	50	BMPR1B
3.540e-02	-3.34	SLC1A2 (solute carrier family 1 member 2)	protein interactions	6506	14	1	19454	50	SLC1A2
3.540e-02	-3.34	DACT2 (dishevelled binding antagonist of beta catenin 2)	protein interactions	168002	14	1	19454	50	ZBTB20
3.540e-02	-3.34	MB (myoglobin)	protein interactions	4151	14	1	19454	50	MAML2
3.540e-02	-3.34	SPRR2D (small proline rich protein 2D)	protein interactions	6703	14	1	19454	50	PPP2R2B
3.540e-02	-3.34	BOD1L2 (biorientation of chromosomes in cell division 1 like 2)	protein interactions	284257	14	1	19454	50	FMN2
3.540e-02	-3.34	Nedd4 (neural precursor cell expressed, developmentally down-regulated 4)	protein interactions	17999	14	1	19454	50	GLIS3
3.540e-02	-3.34	AZIN2 (antizyme inhibitor 2)	protein interactions	113451	14	1	19454	50	TPD52L1
3.540e-02	-3.34	FCGBP (Fc gamma binding protein)	protein interactions	8857	14	1	19454	50	PPP2R2B
3.540e-02	-3.34	GAGE1 (G antigen 1)	protein interactions	2543	14	1	19454	50	PRKG1
3.540e-02	-3.34	Asap1 (ArfGAP with SH3 domain, ankyrin repeat and PH domain1)	protein interactions	13196	14	1	19454	50	MACF1
3.540e-02	-3.34	PLXNA4 (plexin A4)	protein interactions	91584	14	1	19454	50	GPM6A
3.553e-02	-3.34	GATA_ZN_FINGER_2	prosite domains	PS50114	11	1	12186	40	TRPS1
3.553e-02	-3.34	RECEPTOR_TYR_KIN_II	prosite domains	PS00239	11	1	12186	40	NTRK2
3.574e-02	-3.33	human chr11q25	chromosome location	human chr11q25	19	1	26134	50	NTM
3.574e-02	-3.33	human chr5p15.2	chromosome location	human chr5p15.2	19	1	26134	50	CTNND2
3.574e-02	-3.33	human chr6q24.1	chromosome location	human chr6q24.1	19	1	26134	50	NHSL1
3.576e-02	-3.33	LAMTOR1 (late endosomal/lysosomal adaptor, MAPK and MTOR activator 1)	protein interactions	55004	714	5	19454	50	DTNA,FMN2,TNIK,TPD52L1,SLC1A3
3.585e-02	-3.33	Estrogen signaling pathway	KEGG pathways	ko04915	98	2	7161	22	ITPR2,ADCY2
3.585e-02	-3.33	Estrogen signaling pathway	KEGG pathways	hsa04915	98	2	7161	22	ITPR2,ADCY2
3.603e-02	-3.32	active monoatomic ion transmembrane transporter activity	molecular function	GO:0022853	274	3	18094	48	SLC1A3,SLC1A2,ATP1A2
3.612e-02	-3.32	chromophobe_renal_cell_carcinoma	COSMIC cancer mutations	chromophobe_renal_cell_carcinoma	430	4	16828	49	TNIK,BMPR1B,PRKG1,NTRK2
3.612e-02	-3.32	kidney-carcinoma-chromophobe_renal_cell_carcinoma	COSMIC cancer mutations	kidney-carcinoma-chromophobe_renal_cell_carcinoma	430	4	16828	49	PRKG1,TNIK,BMPR1B,NTRK2
3.621e-02	-3.32	regulation of nervous system development	biological process	GO:0051960	456	4	18204	50	NTRK2,PTPRZ1,MACF1,QKI
3.627e-02	-3.32	Ion_trans	pfam domains	PF00520	109	2	17795	49	ITPR2,RYR3
3.642e-02	-3.31	ELK3 (ETS transcription factor ELK3)	protein interactions	2004	117	2	19454	50	NFIA,TRPS1
3.652e-02	-3.31	microtubule minus-end binding	molecular function	GO:0051011	14	1	18094	48	MACF1
3.668e-02	-3.31	CAV1 (caveolin 1)	protein interactions	857	719	5	19454	50	FMN2,DTNA,MACF1,TNIK,SLC1A3
3.670e-02	-3.31	phosphatidylinositol binding	molecular function	GO:0035091	276	3	18094	48	PITPNC1,ITPR2,PARD3B
3.670e-02	-3.31	glycosyltransferase activity	molecular function	GO:0016757	276	3	18094	48	FUT9,MGAT4C,CSGALNACT1
3.670e-02	-3.30	positive regulation of cell development	biological process	GO:0010720	458	4	18204	50	NTRK2,PTPRZ1,MACF1,QKI
3.684e-02	-3.30	positive regulation of cell differentiation	biological process	GO:0045597	906	6	18204	50	NTRK2,SOX5,QKI,BMPR1B,MACF1,PTPRZ1
3.695e-02	-3.30	synaptic signaling	biological process	GO:0099536	459	4	18204	50	SLC1A2,DTNA,NTRK2,SLC1A3
3.699e-02	-3.30	VSIG8 (V-set and immunoglobulin domain containing 8)	protein interactions	391123	118	2	19454	50	CSGALNACT1,SPARCL1
3.702e-02	-3.30	arm	COSMIC cancer mutations	arm	1331	8	16828	49	NPAS3,ZBTB20,MACF1,PARD3B,TRPS1,SORBS1,NTM,ATP1A2
3.721e-02	-3.29	central_nervous_system-hypothalamus-glioma-astrocytoma_Grade_I	COSMIC cancer mutations	central_nervous_system-hypothalamus-glioma-astrocytoma_Grade_I	13	1	16828	49	QKI
3.721e-02	-3.29	skin-scalp-malignant_melanoma-nodular	COSMIC cancer mutations	skin-scalp-malignant_melanoma-nodular	13	1	16828	49	PREX2
3.721e-02	-3.29	skin-shoulder-malignant_melanoma-nodular	COSMIC cancer mutations	skin-shoulder-malignant_melanoma-nodular	13	1	16828	49	PREX2
3.728e-02	-3.29	Inhibition of adenylate cyclase pathway	REACTOME pathways	R-HSA-997269	15	1	10285	26	ADCY2
3.728e-02	-3.29	N-Glycan antennae elongation	REACTOME pathways	R-HSA-975577	15	1	10285	26	MGAT4C
3.728e-02	-3.29	Adenylate cyclase inhibitory pathway	REACTOME pathways	R-HSA-170670	15	1	10285	26	ADCY2
3.745e-02	-3.28	DHFR2 (dihydrofolate reductase 2)	protein interactions	200895	287	3	19454	50	SLC1A3,ITPR2,CPE
3.749e-02	-3.28	Trehalose Degradation	SMPDB pathways	SMP0000467	13	1	1369	4	ATP1A2
3.756e-02	-3.28	RBM7 (RNA binding motif protein 7)	protein interactions	10179	119	2	19454	50	PPP2R2B,QKI
3.779e-02	-3.28	glutathione biosynthetic process	biological process	GO:0006750	14	1	18204	50	SLC1A2
3.779e-02	-3.28	relaxation of cardiac muscle	biological process	GO:0055119	14	1	18204	50	ATP1A2
3.779e-02	-3.28	response to forskolin	biological process	GO:1904321	14	1	18204	50	ADCY2
3.779e-02	-3.28	cellular response to purine-containing compound	biological process	GO:0071415	14	1	18204	50	RYR3
3.779e-02	-3.28	negative regulation of sodium ion transmembrane transporter activity	biological process	GO:2000650	14	1	18204	50	ATP1A2
3.779e-02	-3.28	cellular response to forskolin	biological process	GO:1904322	14	1	18204	50	ADCY2
3.779e-02	-3.28	regulation of protein K63-linked ubiquitination	biological process	GO:1900044	14	1	18204	50	SASH1
3.779e-02	-3.28	sodium ion export across plasma membrane	biological process	GO:0036376	14	1	18204	50	ATP1A2
3.779e-02	-3.28	cellular response to ethanol	biological process	GO:0071361	14	1	18204	50	ITPR2
3.779e-02	-3.28	mechanosensory behavior	biological process	GO:0007638	14	1	18204	50	SLC1A3
3.780e-02	-3.28	axolemma	cellular component	GO:0030673	15	1	19108	49	SLC1A2
3.788e-02	-3.27	RNASE13 (ribonuclease A family member 13 (inactive))	protein interactions	440163	15	1	19454	50	CPE
3.788e-02	-3.27	IGSF1 (immunoglobulin superfamily member 1)	protein interactions	3547	15	1	19454	50	BMPR1B
3.788e-02	-3.27	NPR1 (natriuretic peptide receptor 1)	protein interactions	4881	15	1	19454	50	PRKG1
3.788e-02	-3.27	TAFA5 (TAFA chemokine like family member 5)	protein interactions	25817	15	1	19454	50	NEBL
3.788e-02	-3.27	XIRP1 (xin actin binding repeat containing 1)	protein interactions	165904	15	1	19454	50	NEBL
3.788e-02	-3.27	TIAM2 (TIAM Rac1 associated GEF 2)	protein interactions	26230	15	1	19454	50	TNIK
3.788e-02	-3.27	TESPA1 (thymocyte expressed, positive selection associated 1)	protein interactions	9840	15	1	19454	50	ITPR2
3.788e-02	-3.27	PCSK1N (proprotein convertase subtilisin/kexin type 1 inhibitor)	protein interactions	27344	15	1	19454	50	MGAT4C
3.788e-02	-3.27	Retrograde endocannabinoid signaling	KEGG pathways	ko04723	101	2	7161	22	ITPR2,ADCY2
3.788e-02	-3.27	Retrograde endocannabinoid signaling	KEGG pathways	hsa04723	101	2	7161	22	ADCY2,ITPR2
3.788e-02	-3.27	GATA	pfam domains	PF00320	14	1	17795	49	TRPS1
3.794e-02	-3.27	rhythmic process	biological process	GO:0048511	270	3	18204	50	NTRK2,RORA,BMPR1B
3.794e-02	-3.27	regulation of gliogenesis	biological process	GO:0014013	112	2	18204	50	QKI,PTPRZ1
3.810e-02	-3.27	CEP128 (centrosomal protein 128)	protein interactions	145508	289	3	19454	50	NEBL,ABLIM1,SORBS1
3.838e-02	-3.26	response to organonitrogen compound	biological process	GO:0010243	915	6	18204	50	SORBS1,SLC1A2,SLC1A3,TNIK,RYR3,ITPR2
3.851e-02	-3.26	stomach-carcinoma	COSMIC cancer mutations	stomach-carcinoma	439	4	16828	49	PRKG1,BMPR1B,TNIK,NTRK2
3.855e-02	-3.26	solute:monoatomic cation symporter activity	molecular function	GO:0015294	117	2	18094	48	SLC1A2,SLC1A3
3.856e-02	-3.26	metencephalon development	biological process	GO:0022037	113	2	18204	50	PRKG1,RORA
3.857e-02	-3.26	Glucagon signaling pathway	KEGG pathways	ko04922	102	2	7161	22	ADCY2,ITPR2
3.857e-02	-3.26	Glucagon signaling pathway	KEGG pathways	hsa04922	102	2	7161	22	ADCY2,ITPR2
3.870e-02	-3.25	CNMP_BINDING_2	prosite domains	PS00889	12	1	12186	40	PRKG1
3.872e-02	-3.25	MED15 (mediator complex subunit 15)	protein interactions	51586	121	2	19454	50	QKI,NFIA
3.880e-02	-3.25	skin-scalp-carcinoma-squamous_cell_carcinoma	COSMIC cancer mutations	skin-scalp-carcinoma-squamous_cell_carcinoma	1596	9	16828	49	PTPRZ1,TRPS1,LSAMP,GPC5,ATP1A2,SOX5,MACF1,RORA,PRKG1
3.881e-02	-3.25	bone-humerus-Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour	COSMIC cancer mutations	bone-humerus-Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour	107	2	16828	49	PARD3B,NEBL
3.881e-02	-3.25	Glycosaminoglycan metabolism	REACTOME pathways	R-HSA-1630316	124	2	10285	26	CSGALNACT1,GPC5
3.908e-02	-3.24	tropomyosin binding	molecular function	GO:0005523	15	1	18094	48	NEBL
3.908e-02	-3.24	phosphatidylglycerol binding	molecular function	GO:1901611	15	1	18094	48	PITPNC1
3.908e-02	-3.24	filamin binding	molecular function	GO:0031005	15	1	18094	48	NEBL
3.908e-02	-3.24	neurexin family protein binding	molecular function	GO:0042043	15	1	18094	48	CPE
3.918e-02	-3.24	regulation of circadian rhythm	biological process	GO:0042752	114	2	18204	50	PRKG1,RORA
3.930e-02	-3.24	BRK1 (BRICK1 subunit of SCAR/WAVE actin nucleating complex)	protein interactions	55845	122	2	19454	50	NHSL1,DTNA
3.930e-02	-3.24	MED31 (mediator complex subunit 31)	protein interactions	51003	122	2	19454	50	QKI,CPE
3.934e-02	-3.24	SH3DOMAIN	prints domains	PR00452	83	2	5227	20	SORBS1,NEBL
3.943e-02	-3.23	dermatan sulfate biosynthesis	BIOCYC pathways	HUMAN_PWY-6571	12	1	902	3	CSGALNACT1
3.943e-02	-3.23	human chr13q31.3	chromosome location	human chr13q31.3	21	1	26134	50	GPC5
3.943e-02	-3.23	human chr4q32.3	chromosome location	human chr4q32.3	21	1	26134	50	CPE
3.948e-02	-3.23	bone-Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour	COSMIC cancer mutations	bone-Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour	6023	24	16828	49	ITPR2,ATP1A2,NPAS3,ADCY2,ZBTB20,ABLIM1,MACF1,PREX2,RORA,NKAIN3,DTNA,PTPRZ1,NTRK2,SASH1,CTNND2,GLIS3,SOX5,NEBL,CSGALNACT1,SPARCL1,SLC1A3,RYR3,TPD52L1,MAML2
3.972e-02	-3.23	Rap1 signalling	REACTOME pathways	R-HSA-392517	16	1	10285	26	PRKG1
3.972e-02	-3.23	PKA activation	REACTOME pathways	R-HSA-163615	16	1	10285	26	ADCY2
3.975e-02	-3.23	Znf_GATA	interpro domains	IPR000679	15	1	18521	50	TRPS1
3.975e-02	-3.23	FH2_Formin_sf	interpro domains	IPR042201	15	1	18521	50	FMN2
3.975e-02	-3.23	ATPase_P-typ_cation-transptr_C	interpro domains	IPR006068	15	1	18521	50	ATP1A2
3.975e-02	-3.23	CNH_dom	interpro domains	IPR001180	15	1	18521	50	TNIK
3.975e-02	-3.23	FH2_Formin	interpro domains	IPR015425	15	1	18521	50	FMN2
3.988e-02	-3.22	PAX7 (paired box 7)	protein interactions	5081	123	2	19454	50	NFIA,TRPS1
4.008e-02	-3.22	learning or memory	biological process	GO:0007611	276	3	18204	50	NTRK2,ATP1A2,PTPRZ1
4.008e-02	-3.22	transcription cis-regulatory region binding	molecular function	GO:0000976	1485	8	18094	48	SOX5,NFIA,GLIS3,NPAS3,TRPS1,RFX4,RORA,ZBTB20
4.023e-02	-3.21	Prot_kinase_dom	interpro domains	IPR000719	480	4	18521	50	TNIK,PRKG1,BMPR1B,NTRK2
4.027e-02	-3.21	postsynaptic density, intracellular component	cellular component	GO:0099092	16	1	19108	49	TNIK
4.035e-02	-3.21	transcription regulatory region nucleic acid binding	molecular function	GO:0001067	1487	8	18094	48	GLIS3,SOX5,ZBTB20,RFX4,NPAS3,NFIA,RORA,TRPS1
4.035e-02	-3.21	AMMECR1L (AMMECR1 like)	protein interactions	83607	16	1	19454	50	MACF1
4.035e-02	-3.21	GABRR1 (gamma-aminobutyric acid type A receptor subunit rho1)	protein interactions	2569	16	1	19454	50	PRKG1
4.035e-02	-3.21	GALNT13 (polypeptide N-acetylgalactosaminyltransferase 13)	protein interactions	114805	16	1	19454	50	TNIK
4.035e-02	-3.21	TWIST2 (twist family bHLH transcription factor 2)	protein interactions	117581	16	1	19454	50	ZBTB20
4.035e-02	-3.21	Sumo3 (small ubiquitin-like modifier 3)	protein interactions	20610	16	1	19454	50	ITPR2
4.035e-02	-3.21	TPD52L3 (TPD52 like 3)	protein interactions	89882	16	1	19454	50	TPD52L1
4.035e-02	-3.21	SAPCD1 (suppressor APC domain containing 1)	protein interactions	401251	16	1	19454	50	CTNNA2
4.035e-02	-3.21	CDH12 (cadherin 12)	protein interactions	1010	16	1	19454	50	CTNNA2
4.035e-02	-3.21	ORM2 (orosomucoid 2)	protein interactions	5005	16	1	19454	50	PPP2R2B
4.035e-02	-3.21	FNDC8 (fibronectin type III domain containing 8)	protein interactions	54752	16	1	19454	50	SPARCL1
4.043e-02	-3.21	positive regulation of glycogen biosynthetic process	biological process	GO:0045725	15	1	18204	50	SORBS1
4.043e-02	-3.21	collateral sprouting	biological process	GO:0048668	15	1	18204	50	PRKG1
4.043e-02	-3.21	sarcoplasmic reticulum calcium ion transport	biological process	GO:0070296	15	1	18204	50	RYR3
4.043e-02	-3.21	cerebellar Purkinje cell layer formation	biological process	GO:0021694	15	1	18204	50	RORA
4.043e-02	-3.21	intracellular potassium ion homeostasis	biological process	GO:0030007	15	1	18204	50	ATP1A2
4.043e-02	-3.21	negative regulation of sodium ion transmembrane transport	biological process	GO:1902306	15	1	18204	50	ATP1A2
4.043e-02	-3.21	neuroblast division	biological process	GO:0055057	15	1	18204	50	SOX5
4.043e-02	-3.21	negative regulation of amino acid transport	biological process	GO:0051956	15	1	18204	50	PRKG1
4.043e-02	-3.21	regulation of inositol phosphate biosynthetic process	biological process	GO:0010919	15	1	18204	50	PRKG1
4.043e-02	-3.21	peripheral nervous system neuron development	biological process	GO:0048935	15	1	18204	50	NTRK2
4.043e-02	-3.21	synapse maturation	biological process	GO:0060074	15	1	18204	50	NFIA
4.043e-02	-3.21	peripheral nervous system neuron differentiation	biological process	GO:0048934	15	1	18204	50	NTRK2
4.043e-02	-3.21	protein homotrimerization	biological process	GO:0070207	15	1	18204	50	SLC1A2
4.043e-02	-3.21	response to caffeine	biological process	GO:0031000	15	1	18204	50	RYR3
4.043e-02	-3.21	regulation of neuron projection arborization	biological process	GO:0150011	15	1	18204	50	MACF1
4.043e-02	-3.21	exit from mitosis	biological process	GO:0010458	15	1	18204	50	NFIA
4.053e-02	-3.21	FH2	pfam domains	PF02181	15	1	17795	49	FMN2
4.053e-02	-3.21	CNH	pfam domains	PF00780	15	1	17795	49	TNIK
4.053e-02	-3.21	Cation_ATPase_C	pfam domains	PF00689	15	1	17795	49	ATP1A2
4.055e-02	-3.21	positive regulation of MAPK cascade	biological process	GO:0043410	473	4	18204	50	TNIK,NTRK2,TPD52L1,SASH1
4.066e-02	-3.20	papillary_renal_cell_carcinoma	COSMIC cancer mutations	papillary_renal_cell_carcinoma	6364	25	16828	49	RYR3,NFIA,BMPR1B,RFX4,MAML2,PITPNC1,ATP1A2,CPE,ITPR2,PRKG1,TNIK,ZBTB20,ADCY2,RORA,ABLIM1,MACF1,PREX2,GPC5,CTNND2,PTPRZ1,SASH1,NTRK2,NTM,FMN2,SOX5
4.066e-02	-3.20	kidney-carcinoma-papillary_renal_cell_carcinoma	COSMIC cancer mutations	kidney-carcinoma-papillary_renal_cell_carcinoma	6364	25	16828	49	CPE,ATP1A2,ITPR2,TNIK,PRKG1,PREX2,ABLIM1,MACF1,RORA,ADCY2,ZBTB20,CTNND2,GPC5,SASH1,NTRK2,NTM,PTPRZ1,FMN2,SOX5,RYR3,BMPR1B,NFIA,RFX4,MAML2,PITPNC1
4.080e-02	-3.20	regulation of GTPase activity	biological process	GO:0043087	278	3	18204	50	NTRK2,PREX2,PRKG1
4.080e-02	-3.20	actin filament organization	biological process	GO:0007015	278	3	18204	50	FMN2,NEBL,SORBS1
4.092e-02	-3.20	phosphorus metabolic process	biological process	GO:0006793	1707	9	18204	50	RORA,TNIK,BMPR1B,PTPRZ1,PRKG1,ATP1A2,NTRK2,CSGALNACT1,ADCY2
4.099e-02	-3.19	SH3	smart domains	SM00326	202	3	9717	37	SORBS1,NEBL,SASH1
4.159e-02	-3.18	circulatory system development	biological process	GO:0072359	933	6	18204	50	NEBL,PRKG1,RORA,CPE,QKI,NTRK2
4.163e-02	-3.18	oxysterol binding	molecular function	GO:0008142	16	1	18094	48	RORA
4.163e-02	-3.18	cGMP binding	molecular function	GO:0030553	16	1	18094	48	PRKG1
4.163e-02	-3.18	adenylate cyclase activity	molecular function	GO:0004016	16	1	18094	48	ADCY2
4.163e-02	-3.18	mitogen-activated protein kinase kinase kinase binding	molecular function	GO:0031435	16	1	18094	48	SASH1
4.166e-02	-3.18	SYP (synaptophysin)	protein interactions	6855	126	2	19454	50	PITPNC1,GPM6A
4.168e-02	-3.18	positive regulation of phosphate metabolic process	biological process	GO:0045937	697	5	18204	50	NTRK2,TNIK,TPD52L1,SASH1,ZBTB20
4.168e-02	-3.18	positive regulation of phosphorus metabolic process	biological process	GO:0010562	697	5	18204	50	NTRK2,TNIK,TPD52L1,SASH1,ZBTB20
4.169e-02	-3.18	Formin, FH2 domain	gene3d domains	1.20.58.2220	15	1	14470	41	FMN2
4.186e-02	-3.17	CARBOXYPEPT_ZN_2	prosite domains	PS00133	13	1	12186	40	CPE
4.186e-02	-3.17	CARBOXYPEPT_ZN_1	prosite domains	PS00132	13	1	12186	40	CPE
4.195e-02	-3.17	positive regulation of cellular metabolic process	biological process	GO:0031325	3164	14	18204	50	TNIK,MAML2,BMPR1B,GLIS3,SORBS1,RFX4,NFIA,NTRK2,NPAS3,QKI,TPD52L1,RORA,ZBTB20,SASH1
4.210e-02	-3.17	cellular response to organic substance	biological process	GO:0071310	1716	9	18204	50	RORA,SLC1A3,ATP1A2,RYR3,ZBTB20,ITPR2,ADCY2,SORBS1,SLC1A2
4.215e-02	-3.17	PKA activation in glucagon signalling	REACTOME pathways	R-HSA-164378	17	1	10285	26	ADCY2
4.215e-02	-3.17	Elevation of cytosolic Ca2+ levels	REACTOME pathways	R-HSA-139853	17	1	10285	26	ITPR2
4.215e-02	-3.17	PKA-mediated phosphorylation of CREB	REACTOME pathways	R-HSA-111931	17	1	10285	26	ADCY2
4.235e-02	-3.16	cNMP-bd_CS	interpro domains	IPR018488	16	1	18521	50	PRKG1
4.235e-02	-3.16	CarboxyPept-like_regulatory	interpro domains	IPR008969	16	1	18521	50	CPE
4.250e-02	-3.16	lung-middle_lobe-carcinoma-adenocarcinoma	COSMIC cancer mutations	lung-middle_lobe-carcinoma-adenocarcinoma	1368	8	16828	49	SASH1,ITPR2,CPE,ATP1A2,RYR3,CTNND2,MACF1,PARD3B
4.267e-02	-3.15	neuron projection terminus	cellular component	GO:0044306	128	2	19108	49	SLC1A2,NTRK2
4.282e-02	-3.15	hypothalamus	COSMIC cancer mutations	hypothalamus	15	1	16828	49	QKI
4.282e-02	-3.15	RASL12 (RAS like family 12)	protein interactions	51285	17	1	19454	50	BMPR1B
4.282e-02	-3.15	TAGAP (T cell activation RhoGTPase activating protein)	protein interactions	117289	17	1	19454	50	DTNA
4.282e-02	-3.15	Pef1 (penta-EF hand domain containing 1)	protein interactions	67898	17	1	19454	50	QKI
4.282e-02	-3.15	DPP6 (dipeptidyl peptidase like 6)	protein interactions	1804	17	1	19454	50	GPM6A
4.282e-02	-3.15	SEPSECS (Sep (O-phosphoserine) tRNA:Sec (selenocysteine) tRNA synthase)	protein interactions	51091	17	1	19454	50	ABLIM1
4.282e-02	-3.15	Shcbp1 (Shc SH2-domain binding protein 1)	protein interactions	20419	17	1	19454	50	GPC5
4.282e-02	-3.15	PAX4 (paired box 4)	protein interactions	5078	17	1	19454	50	NTM
4.282e-02	-3.15	NOTCH4 (notch receptor 4)	protein interactions	4855	17	1	19454	50	MAML2
4.282e-02	-3.15	MSANTD2 (Myb/SANT DNA binding domain containing 2)	protein interactions	79684	17	1	19454	50	SOX5
4.282e-02	-3.15	Sqstm1 (sequestosome 1)	protein interactions	18412	17	1	19454	50	BMPR1B
4.286e-02	-3.15	MYB (MYB proto-oncogene, transcription factor)	protein interactions	4602	128	2	19454	50	NFIA,TRPS1
4.286e-02	-3.15	TEAD2 (TEA domain transcription factor 2)	protein interactions	8463	128	2	19454	50	ZBTB20,TRPS1
4.286e-02	-3.15	ATF7IP (activating transcription factor 7 interacting protein)	protein interactions	55729	128	2	19454	50	SOX5,MACF1
4.297e-02	-3.15	RAC1 (Rac family small GTPase 1)	protein interactions	5879	1005	6	19454	50	SLC1A3,PREX2,MACF1,DTNA,PPP2R2B,FMN2
4.307e-02	-3.14	regulation of amino acid transmembrane transport	biological process	GO:1903789	16	1	18204	50	ATP1A2
4.307e-02	-3.14	asymmetric cell division	biological process	GO:0008356	16	1	18204	50	SOX5
4.307e-02	-3.14	regulation of respiratory system process	biological process	GO:0044065	16	1	18204	50	ATP1A2
4.307e-02	-3.14	insulin metabolic process	biological process	GO:1901142	16	1	18204	50	CPE
4.307e-02	-3.14	cardiac left ventricle morphogenesis	biological process	GO:0003214	16	1	18204	50	CPE
4.307e-02	-3.14	nonribosomal peptide biosynthetic process	biological process	GO:0019184	16	1	18204	50	SLC1A2
4.307e-02	-3.14	regulation of amino acid import across plasma membrane	biological process	GO:0010958	16	1	18204	50	ATP1A2
4.307e-02	-3.14	locomotory exploration behavior	biological process	GO:0035641	16	1	18204	50	ATP1A2
4.307e-02	-3.14	fucose metabolic process	biological process	GO:0006004	16	1	18204	50	FUT9
4.307e-02	-3.14	non-proteinogenic amino acid biosynthetic process	biological process	GO:0170043	16	1	18204	50	SLC1A3
4.311e-02	-3.14	human chr5p15.31	chromosome location	human chr5p15.31	23	1	26134	50	ADCY2
4.321e-02	-3.14	CARM1 (coactivator associated arginine methyltransferase 1)	protein interactions	10498	304	3	19454	50	QKI,RORA,DTNA
4.329e-02	-3.14	ovary-carcinoma-mucinous_carcinoma	COSMIC cancer mutations	ovary-carcinoma-mucinous_carcinoma	456	4	16828	49	BMPR1B,TNIK,PRKG1,NTRK2
4.334e-02	-3.14	ovary-carcinoma-clear_cell_carcinoma	COSMIC cancer mutations	ovary-carcinoma-clear_cell_carcinoma	665	5	16828	49	NTRK2,PRKG1,SPARCL1,BMPR1B,TNIK
4.337e-02	-3.14	positive regulation of metabolic process	biological process	GO:0009893	3796	16	18204	50	SASH1,FMN2,ZBTB20,RORA,TPD52L1,QKI,NPAS3,NFIA,NTRK2,GLIS3,SORBS1,RFX4,BMPR1B,MAML2,TNIK,SFXN5
4.338e-02	-3.14	positive regulation of macromolecule metabolic process	biological process	GO:0010604	3485	15	18204	50	QKI,NPAS3,NTRK2,NFIA,RFX4,SORBS1,GLIS3,FMN2,SASH1,ZBTB20,RORA,TPD52L1,BMPR1B,MAML2,TNIK
4.340e-02	-3.14	cell junction assembly	biological process	GO:0034329	285	3	18204	50	GPM6A,CDH20,SORBS1
4.346e-02	-3.14	CHD7 (chromodomain helicase DNA binding protein 7)	protein interactions	55636	129	2	19454	50	ZBTB20,SOX5
4.388e-02	-3.13	mucinous_carcinoma	COSMIC cancer mutations	mucinous_carcinoma	458	4	16828	49	NTRK2,PRKG1,TNIK,BMPR1B
4.388e-02	-3.13	Z disc	cellular component	GO:0030018	130	2	19108	49	RYR3,NEBL
4.407e-02	-3.12	PKP1 (plakophilin 1)	protein interactions	5317	130	2	19454	50	CSGALNACT1,PPP2R2B
4.410e-02	-3.12	prostate-adenoma	COSMIC cancer mutations	prostate-adenoma	1634	9	16828	49	GPC5,SASH1,PTPRZ1,PRKG1,NEBL,MACF1,SOX5,NPAS3,ZBTB20
4.417e-02	-3.12	transmembrane receptor protein tyrosine phosphatase activity	molecular function	GO:0005001	17	1	18094	48	PTPRZ1
4.417e-02	-3.12	transmembrane receptor protein phosphatase activity	molecular function	GO:0019198	17	1	18094	48	PTPRZ1
4.428e-02	-3.12	clear_cell_carcinoma	COSMIC cancer mutations	clear_cell_carcinoma	669	5	16828	49	BMPR1B,TNIK,PRKG1,SPARCL1,NTRK2
4.432e-02	-3.12	MFAP5-mediated ovarian cancer cell motility and invasiveness	WikiPathways	WP3301	12	1	5310	20	RYR3
4.432e-02	-3.12	Bone Morphogenic Protein (BMP) Signalling and Regulation	WikiPathways	WP1425	12	1	5310	20	BMPR1B
4.448e-02	-3.11	PDZ	pfam domains	PF00595	122	2	17795	49	PREX2,PARD3B
4.457e-02	-3.11	cGMP effects	REACTOME pathways	R-HSA-418457	18	1	10285	26	PRKG1
4.468e-02	-3.11	TRPS1 (transcriptional repressor GATA binding 1)	protein interactions	7227	131	2	19454	50	SOX5,NFIA
4.468e-02	-3.11	NCOA2 (nuclear receptor coactivator 2)	protein interactions	10499	131	2	19454	50	NFIA,RORA
4.468e-02	-3.11	ZNF609 (zinc finger protein 609)	protein interactions	23060	131	2	19454	50	NFIA,SOX5
4.472e-02	-3.11	middle_lobe	COSMIC cancer mutations	middle_lobe	1382	8	16828	49	SASH1,ITPR2,ATP1A2,CPE,CTNND2,RYR3,MACF1,PARD3B
4.477e-02	-3.11	ZnF_GATA	smart domains	SM00401	12	1	9717	37	TRPS1
4.477e-02	-3.11	DWA	smart domains	SM00523	12	1	9717	37	NFIA
4.482e-02	-3.11	system process	biological process	GO:0003008	2015	10	18204	50	NTRK2,DTNA,ABLIM1,SLC1A2,CTNNA2,SLC1A3,ATP1A2,PRKG1,RYR3,PTPRZ1
4.493e-02	-3.10	CA_dom_sf	interpro domains	IPR036398	17	1	18521	50	PTPRZ1
4.493e-02	-3.10	A/G_cyclase_CS	interpro domains	IPR018297	17	1	18521	50	ADCY2
4.493e-02	-3.10	CA_dom	interpro domains	IPR001148	17	1	18521	50	PTPRZ1
4.499e-02	-3.10	AFDN (afadin, adherens junction formation factor)	protein interactions	4301	309	3	19454	50	MACF1,SORBS1,DTNA
4.507e-02	-3.10	ductal_carcinoma	COSMIC cancer mutations	ductal_carcinoma	15798	49	16828	49	CTNND2,SASH1,NTRK2,NTM,PTPRZ1,DTNA,NKAIN3,CSGALNACT1,NEBL,ATP1A2,CPE,TNIK,PRKG1,RORA,MACF1,ZBTB20,LSAMP,TRPS1,MAML2,TPD52L1,FUT9,MGAT4C,SLC1A3,NFIA,BMPR1B,GPM6A,QKI,GLIS3,GPC5,SFXN5,FMN2,PARD3B,SOX5,SLC1A2,ITPR2,MSI2,PREX2,ABLIM1,FBXL7,NPAS3,ADCY2,RFX4,CDH20,PITPNC1,RYR3,SPARCL1,SORBS1,NHSL1,PPP2R2B
4.515e-02	-3.10	Glycosphingolipid biosynthesis - globo and isoglobo series	KEGG pathways	hsa00603	15	1	7161	22	FUT9
4.519e-02	-3.10	protein phosphatase type 2A complex	cellular component	GO:0000159	18	1	19108	49	PPP2R2B
4.529e-02	-3.09	OPCML (opioid binding protein/cell adhesion molecule like)	protein interactions	4978	18	1	19454	50	NTM
4.529e-02	-3.09	SERTAD4 (SERTA domain containing 4)	protein interactions	56256	18	1	19454	50	PPP2R2B
4.529e-02	-3.09	SELL (selectin L)	protein interactions	6402	18	1	19454	50	PRKG1
4.529e-02	-3.09	TTC29 (tetratricopeptide repeat domain 29)	protein interactions	83894	18	1	19454	50	MACF1
4.529e-02	-3.09	NKIRAS1 (NFKB inhibitor interacting Ras like 1)	protein interactions	28512	18	1	19454	50	BMPR1B
4.529e-02	-3.09	ACAP1 (ArfGAP with coiled-coil, ankyrin repeat and PH domains 1)	protein interactions	9744	18	1	19454	50	NEBL
4.529e-02	-3.09	KLHL1 (kelch like family member 1)	protein interactions	57626	18	1	19454	50	BMPR1B
4.529e-02	-3.09	Tgfbr1 (transforming growth factor, beta receptor I)	protein interactions	21812	18	1	19454	50	BMPR1B
4.529e-02	-3.09	Cnot2 (CCR4-NOT transcription complex, subunit 2)	protein interactions	72068	18	1	19454	50	MACF1
4.530e-02	-3.09	IVL (involucrin)	protein interactions	3713	132	2	19454	50	CSGALNACT1,PPP2R2B
4.557e-02	-3.09	cytoskeletal protein binding	molecular function	GO:0008092	989	6	18094	48	FMN2,CTNNA2,SORBS1,NEBL,ABLIM1,MACF1
4.558e-02	-3.09	cellular process	biological process	GO:0009987	14996	46	18204	50	MACF1,GPC5,MAML2,TNIK,CTNNA2,CPE,PREX2,SLC1A3,QKI,RFX4,SORBS1,GLIS3,BMPR1B,PTPRZ1,CTNND2,SFXN5,ABLIM1,SLC1A2,NHSL1,SOX5,ZBTB20,RYR3,FBXL7,PITPNC1,SPARCL1,NEBL,MGAT4C,PPP2R2B,PARD3B,CSGALNACT1,FMN2,ATP1A2,NTM,TPD52L1,MSI2,ADCY2,CDH20,LSAMP,ITPR2,DTNA,PRKG1,RORA,FUT9,NTRK2,GPM6A,NFIA
4.560e-02	-3.09	action potential	biological process	GO:0001508	124	2	18204	50	NTRK2,ATP1A2
4.560e-02	-3.09	cardiocyte differentiation	biological process	GO:0035051	124	2	18204	50	NEBL,PRKG1
4.560e-02	-3.09	positive regulation of lipid metabolic process	biological process	GO:0045834	124	2	18204	50	ZBTB20,SORBS1
4.565e-02	-3.09	ovary-carcinoma-endometrioid_carcinoma	COSMIC cancer mutations	ovary-carcinoma-endometrioid_carcinoma	464	4	16828	49	NTRK2,PRKG1,BMPR1B,TNIK
4.567e-02	-3.09	inorganic ion transmembrane transport	biological process	GO:0098660	715	5	18204	50	ITPR2,ATP1A2,RYR3,SLC1A3,GPM6A
4.569e-02	-3.09	Cholinergic synapse	KEGG pathways	hsa04725	112	2	7161	22	ADCY2,ITPR2
4.570e-02	-3.09	fucosylation	biological process	GO:0036065	17	1	18204	50	FUT9
4.570e-02	-3.09	heparin metabolic process	biological process	GO:0030202	17	1	18204	50	CSGALNACT1
4.570e-02	-3.09	microvillus assembly	biological process	GO:0030033	17	1	18204	50	TNIK
4.570e-02	-3.09	cGMP metabolic process	biological process	GO:0046068	17	1	18204	50	RORA
4.570e-02	-3.09	membrane depolarization during cardiac muscle cell action potential	biological process	GO:0086012	17	1	18204	50	ATP1A2
4.570e-02	-3.09	cell communication by electrical coupling involved in cardiac conduction	biological process	GO:0086064	17	1	18204	50	ATP1A2
4.570e-02	-3.09	positive regulation of glycogen metabolic process	biological process	GO:0070875	17	1	18204	50	SORBS1
4.570e-02	-3.09	retinal rod cell differentiation	biological process	GO:0060221	17	1	18204	50	NTRK2
4.570e-02	-3.09	viral genome replication	biological process	GO:0019079	17	1	18204	50	NFIA
4.570e-02	-3.09	T-helper 17 type immune response	biological process	GO:0072538	17	1	18204	50	RORA
4.570e-02	-3.09	cell migration in hindbrain	biological process	GO:0021535	17	1	18204	50	CTNNA2
4.570e-02	-3.09	ureter development	biological process	GO:0072189	17	1	18204	50	NFIA
4.570e-02	-3.09	protein trimerization	biological process	GO:0070206	17	1	18204	50	SLC1A2
4.570e-02	-3.09	cellular response to ATP	biological process	GO:0071318	17	1	18204	50	RYR3
4.581e-02	-3.08	ZZ	pfam domains	PF00569	17	1	17795	49	DTNA
4.581e-02	-3.08	Carb_anhydrase	pfam domains	PF00194	17	1	17795	49	PTPRZ1
4.607e-02	-3.08	response to hypoxia	biological process	GO:0001666	292	3	18204	50	ITPR2,FMN2,RORA
4.615e-02	-3.08	cell cortex	cellular component	GO:0005938	313	3	19108	49	PARD3B,ITPR2,FMN2
4.623e-02	-3.07	ion binding	molecular function	GO:0043167	6007	22	18094	48	ADCY2,SLC1A3,PRKG1,SLC1A2,SPARCL1,RYR3,ATP1A2,NTRK2,TRPS1,PITPNC1,ITPR2,CPE,GLIS3,MGAT4C,ZBTB20,BMPR1B,ABLIM1,TNIK,RORA,MACF1,DTNA,CSGALNACT1
4.626e-02	-3.07	actomyosin structure organization	biological process	GO:0031032	125	2	18204	50	SORBS1,NEBL
4.631e-02	-3.07	cellular response to growth factor stimulus	biological process	GO:0071363	494	4	18204	50	SOX5,NFIA,NTRK2,BMPR1B
4.671e-02	-3.06	phosphatidylcholine transporter activity	molecular function	GO:0008525	18	1	18094	48	PITPNC1
4.699e-02	-3.06	Defective B3GAT3 causes JDSSDHD	REACTOME pathways	R-HSA-3560801	19	1	10285	26	GPC5
4.699e-02	-3.06	Defective B3GALT6 causes EDSP2 and SEMDJL1	REACTOME pathways	R-HSA-4420332	19	1	10285	26	GPC5
4.699e-02	-3.06	Defective B4GALT7 causes EDS, progeroid type	REACTOME pathways	R-HSA-3560783	19	1	10285	26	GPC5
4.709e-02	-3.06	Signaling by Hedgehog	REACTOME pathways	R-HSA-5358351	138	2	10285	26	GPC5,ADCY2
4.712e-02	-3.06	Alpha carbonic anhydrase	gene3d domains	3.10.200.10	17	1	14470	41	PTPRZ1
4.716e-02	-3.05	SOX15 (SRY-box transcription factor 15)	protein interactions	6665	135	2	19454	50	TRPS1,NFIA
4.722e-02	-3.05	central_nervous_system-brain-glioma-astrocytoma_Grade_IV	COSMIC cancer mutations	central_nervous_system-brain-glioma-astrocytoma_Grade_IV	15813	49	16828	49	SFXN5,FMN2,PARD3B,SOX5,GLIS3,GPC5,MSI2,PREX2,ABLIM1,NPAS3,FBXL7,ADCY2,SLC1A2,ITPR2,CDH20,PITPNC1,RFX4,NHSL1,PPP2R2B,RYR3,SPARCL1,SORBS1,CSGALNACT1,NEBL,CTNND2,NTRK2,SASH1,NTM,PTPRZ1,DTNA,NKAIN3,TNIK,PRKG1,RORA,MACF1,ZBTB20,ATP1A2,CPE,MAML2,TPD52L1,MGAT4C,FUT9,LSAMP,TRPS1,NFIA,BMPR1B,GPM6A,QKI,SLC1A3
4.752e-02	-3.05	Nucleotide_cyclase	interpro domains	IPR029787	18	1	18521	50	ADCY2
4.752e-02	-3.05	A/G_cyclase	interpro domains	IPR001054	18	1	18521	50	ADCY2
4.752e-02	-3.05	ATPase_P-typ_cation-transptr_N	interpro domains	IPR004014	18	1	18521	50	ATP1A2
4.752e-02	-3.05	Leu-rich_rpt_Cys-con_subtyp	interpro domains	IPR006553	18	1	18521	50	FBXL7
4.760e-02	-3.05	response to amino acid	biological process	GO:0043200	127	2	18204	50	SLC1A2,NTRK2
4.760e-02	-3.05	positive regulation of protein serine/threonine kinase activity	biological process	GO:0071902	127	2	18204	50	TPD52L1,SASH1
4.761e-02	-3.04	postsynaptic density	cellular component	GO:0014069	317	3	19108	49	CTNND2,TNIK,NTRK2
4.764e-02	-3.04	postsynaptic specialization, intracellular component	cellular component	GO:0099091	19	1	19108	49	TNIK
4.764e-02	-3.04	astrocyte projection	cellular component	GO:0097449	19	1	19108	49	SLC1A2
4.764e-02	-3.04	parallel fiber to Purkinje cell synapse	cellular component	GO:0098688	19	1	19108	49	GPM6A
4.764e-02	-3.04	cation-transporting ATPase complex	cellular component	GO:0090533	19	1	19108	49	ATP1A2
4.772e-02	-3.04	haematopoietic_and_lymphoid_tissue-abdomen-lymphoid_neoplasm-diffuse_large_B_cell_lymphoma	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue-abdomen-lymphoid_neoplasm-diffuse_large_B_cell_lymphoma	120	2	16828	49	CTNND2,FMN2
4.774e-02	-3.04	SPZ1 (spermatogenic leucine zipper 1)	protein interactions	84654	19	1	19454	50	DTNA
4.774e-02	-3.04	TNR (tenascin R)	protein interactions	7143	19	1	19454	50	PTPRZ1
4.774e-02	-3.04	GCHFR (GTP cyclohydrolase I feedback regulator)	protein interactions	2644	19	1	19454	50	NEBL
4.774e-02	-3.04	PHYHIPL (phytanoyl-CoA 2-hydroxylase interacting protein like)	protein interactions	84457	19	1	19454	50	GPM6A
4.774e-02	-3.04	RIT2 (Ras like without CAAX 2)	protein interactions	6014	19	1	19454	50	DTNA
4.774e-02	-3.04	CNTNAP4 (contactin associated protein family member 4)	protein interactions	85445	19	1	19454	50	MACF1
4.774e-02	-3.04	C3orf62 (chromosome 3 open reading frame 62)	protein interactions	375341	19	1	19454	50	ATP1A2
4.774e-02	-3.04	INKA1 (inka box actin regulator 1)	protein interactions	389119	19	1	19454	50	ZBTB20
4.774e-02	-3.04	PLA2G4E (phospholipase A2 group IVE)	protein interactions	123745	19	1	19454	50	PPP2R2B
4.782e-02	-3.04	regulation of multicellular organismal development	biological process	GO:2000026	1484	8	18204	50	QKI,NTRK2,TRPS1,SOX5,SASH1,BMPR1B,MACF1,PTPRZ1
4.793e-02	-3.04	Cell-type Dependent Selectivity of CCK2R Signaling	WikiPathways	WP3679	13	1	5310	20	RYR3
4.793e-02	-3.04	skin-back-malignant_melanoma	COSMIC cancer mutations	skin-back-malignant_melanoma	280	3	16828	49	PREX2,ATP1A2,TNIK
4.809e-02	-3.03	cAMP signaling	KEGG pathways	hsa_M00695	16	1	7161	22	ADCY2
4.809e-02	-3.03	cAMP signaling	KEGG pathways	M00695	16	1	7161	22	ADCY2
4.809e-02	-3.03	N-glycan biosynthesis, complex type	KEGG pathways	hsa_M00075	16	1	7161	22	MGAT4C
4.809e-02	-3.03	N-glycan biosynthesis, complex type	KEGG pathways	M00075	16	1	7161	22	MGAT4C
4.815e-02	-3.03	FH2	prosite domains	PS51444	15	1	12186	40	FMN2
4.815e-02	-3.03	CNH	prosite domains	PS50219	15	1	12186	40	TNIK
4.827e-02	-3.03	carbohydrate biosynthetic process	biological process	GO:0016051	128	2	18204	50	FUT9,CSGALNACT1
4.827e-02	-3.03	myelination	biological process	GO:0042552	128	2	18204	50	NTRK2,QKI
4.832e-02	-3.03	dendritic spine morphogenesis	biological process	GO:0060997	18	1	18204	50	CTNND2
4.832e-02	-3.03	cardiac myofibril assembly	biological process	GO:0055003	18	1	18204	50	NEBL
4.832e-02	-3.03	regulation of leukocyte tethering or rolling	biological process	GO:1903236	18	1	18204	50	FUT9
4.832e-02	-3.03	negative regulation of anoikis	biological process	GO:2000811	18	1	18204	50	NTRK2
4.832e-02	-3.03	negative regulation of platelet activation	biological process	GO:0010544	18	1	18204	50	PRKG1
4.832e-02	-3.03	negative regulation of sodium ion transport	biological process	GO:0010766	18	1	18204	50	ATP1A2
4.839e-02	-3.03	central_nervous_system-optic_nerve-glioma-astrocytoma_Grade_I	COSMIC cancer mutations	central_nervous_system-optic_nerve-glioma-astrocytoma_Grade_I	17	1	16828	49	QKI
4.839e-02	-3.03	optic_nerve	COSMIC cancer mutations	optic_nerve	17	1	16828	49	QKI
4.842e-02	-3.03	TBL1X (transducin beta like 1 X-linked)	protein interactions	6907	137	2	19454	50	SOX5,NFIA
4.843e-02	-3.03	oligoastrocytoma_Grade_II	COSMIC cancer mutations	oligoastrocytoma_Grade_II	121	2	16828	49	CDH20,DTNA
4.844e-02	-3.03	Guanylate_cyc	pfam domains	PF00211	18	1	17795	49	ADCY2
4.844e-02	-3.03	Cation_ATPase_N	pfam domains	PF00690	18	1	17795	49	ATP1A2
4.859e-02	-3.02	human chr18q12.1	chromosome location	human chr18q12.1	26	1	26134	50	DTNA
4.881e-02	-3.02	Ion Channels and Their Functional Role in Vascular Endothelium	SMPDB pathways	SMP0063778	17	1	1369	4	PRKG1
4.892e-02	-3.02	protein phosphorylation	biological process	GO:0006468	503	4	18204	50	PRKG1,BMPR1B,NTRK2,TNIK
4.894e-02	-3.02	response to organophosphorus	biological process	GO:0046683	129	2	18204	50	RYR3,ITPR2
4.908e-02	-3.01	Transferase(Phosphotransferase) domain 1	gene3d domains	1.10.510.10	490	4	14470	41	NTRK2,BMPR1B,TNIK,PRKG1
4.911e-02	-3.01	sequence-specific double-stranded DNA binding	molecular function	GO:1990837	1547	8	18094	48	NFIA,SOX5,GLIS3,NPAS3,TRPS1,RFX4,RORA,ZBTB20
4.912e-02	-3.01	dermatan sulfate biosynthesis	BIOCYC pathways	META_PWY-6571	15	1	902	3	CSGALNACT1
4.924e-02	-3.01	alkali metal ion binding	molecular function	GO:0031420	19	1	18094	48	ATP1A2
4.924e-02	-3.01	transmembrane receptor protein serine/threonine kinase activity	molecular function	GO:0004675	19	1	18094	48	BMPR1B
4.940e-02	-3.01	ACTA1 (actin alpha 1, skeletal muscle)	protein interactions	58	321	3	19454	50	SORBS1,MACF1,DTNA
4.962e-02	-3.00	ensheathment of neurons	biological process	GO:0007272	130	2	18204	50	QKI,NTRK2
4.962e-02	-3.00	axon ensheathment	biological process	GO:0008366	130	2	18204	50	NTRK2,QKI
4.968e-02	-3.00	DUSP22 (dual specificity phosphatase 22)	protein interactions	56940	139	2	19454	50	CTNNA2,QKI
4.968e-02	-3.00	SPCS2 (signal peptidase complex subunit 2)	protein interactions	9789	139	2	19454	50	GPC5,MGAT4C
4.982e-02	-3.00	Nucleotide cyclase	gene3d domains	3.30.70.1230	18	1	14470	41	ADCY2
4.983e-02	-3.00	PK_Tyr_Ser-Thr	pfam domains	PF07714	130	2	17795	49	BMPR1B,NTRK2
4.987e-02	-3.00	ligand-gated monoatomic cation channel activity	molecular function	GO:0099094	135	2	18094	48	ITPR2,RYR3