Gene Ontology Enrichment Results

Homer de novo Motif Enrichment Results
Known Motif Enrichment Results

Text file version of complete results (i.e. open with Excel)

biological process: Functional groupings of proteins (Gene Ontology)

molecular function: Mechanistic actions of proteins (Gene Ontology)

cellular component: Protein localization (Gene Ontology)

chromosome location: Genes with similar chromosome localization (NCBI Gene)

KEGG pathways: Groups of proteins in the same pathways (KEGG)

protein interactions: "Proteins interacting with a common protein (BIND, EcoCyc, HPRD)" (NCBI Gene)

interpro domains: Proteins with similar domains and features (Interpro)

pfam domains: Proteins with similar domains and features (Pfam)

smart domains: Proteins with similar domains and features (SMART)

gene3d domains: Proteins with similar domains and features (Gene3D)

prosite domains: Proteins with similar domains and features (Prosite)

prints domains: Proteins with similar domains and features (PRINTS)

MSigDB lists: "Genes sets for pathways, factor/miRNA target predictions, expression patterns, etc." (MSigDB)

BIOCYC pathways: Groups of proteins in the same pathways (BIOCYC)

COSMIC cancer mutations: Genes mutated in similar cancers (COSMIC)

GWAS genes: Genes mutated in similar diseases (GWAS Catalog)

Lipid Maps pathways: Groups of proteins in the same lipid pathways (Lipid Maps/Biosystems)

Pathway Interaction DB: Groups of proteins in the same pathways (Pathway Interaction Database)

REACTOME pathways: Groups of proteins in the same pathways (REACTOME)

SMPDB pathways: Groups of proteins in the same pathways (SMPDB)

WikiPathways: Groups of proteins in the same pathways (Wikipathways)

Enriched Categories

P-value	ln(P)	Term	GO Tree	GO ID	# of Genes in Term	# of Target Genes in Term	# of Total Genes	# of Target Genes	Common Genes
3.692e-08	-17.11	nervous system development	biological process	GO:0007399	2185	21	18204	48	LSAMP,SLC1A2,MEIS2,PARD3,MSI2,RORA,NTM,TNIK,ATP1A2,RFX4,NFIA,GPM6A,SOX5,SLC1A3,PCDH9,CAMK2G,BMPR1B,LRIG1,CTNND2,CTNNA2,NRXN1
4.239e-07	-14.67	lymph_node	COSMIC cancer mutations	lymph_node	1703	18	16828	48	CTNND2,LSAMP,GPC5,CAMK2G,PCDH9,PARD3,ATP13A4,SFXN5,SLC1A3,TNIK,GPM6A,FGFR3,PARD3B,SOX5,RYR3,ACSS1,DTNA,MEIS2
5.049e-07	-14.50	haematopoietic_and_lymphoid_tissue-haematopoietic_neoplasm-myelodysplastic_syndrome	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue-haematopoietic_neoplasm-myelodysplastic_syndrome	1174	15	16828	48	FGFR3,NPAS3,RYR3,SOX5,SLC1A2,TNIK,NKAIN3,COL5A3,FBXL7,CAMK2G,NFIA,LSAMP,BMPR1B,PARD3,ATP1A2
5.049e-07	-14.50	myelodysplastic_syndrome	COSMIC cancer mutations	myelodysplastic_syndrome	1174	15	16828	48	BMPR1B,PARD3,ATP1A2,FBXL7,COL5A3,CAMK2G,NFIA,LSAMP,NKAIN3,FGFR3,NPAS3,SLC1A2,RYR3,SOX5,TNIK
5.483e-07	-14.42	prostate-carcinoma	COSMIC cancer mutations	prostate-carcinoma	9000	42	16828	48	SLC25A18,CTNND2,ZNRF3,GPC5,FBXL7,COL5A3,NHSL1,BMPR1B,PARD3,LRIG1,NTM,RORA,HIF3A,GPM6A,FGFR3,RFX4,SOX5,SLC4A4,MEIS2,NKAIN3,NFIA,GLIS3,PITPNC1,LSAMP,CDH20,MSI2,ZBTB20,PCDH9,SORBS1,NRXN1,ATP13A4,SFXN5,SPARCL1,TNIK,SLC1A3,NPAS3,PARD3B,SLC1A2,RYR3,AHCYL2,ABLIM1,DTNA
2.102e-06	-13.07	chondroblastoma	COSMIC cancer mutations	chondroblastoma	534	10	16828	48	NKAIN3,SFXN5,PCDH9,AHCYL2,RYR3,SOX5,GPC5,LSAMP,GPM6A,CTNND2
2.238e-06	-13.01	Burkitt_lymphoma	COSMIC cancer mutations	Burkitt_lymphoma	2119	19	16828	48	PCDH9,NHSL1,ATP13A4,LRIG1,PARD3,BMPR1B,LSAMP,CTNND2,GPC5,FBXL7,AHCYL2,NKAIN3,GPM6A,SLC1A3,SLC1A2,RFX4,RYR3,SOX5,NPAS3
2.238e-06	-13.01	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-Burkitt_lymphoma	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-Burkitt_lymphoma	2119	19	16828	48	LSAMP,CTNND2,FBXL7,GPC5,PCDH9,NHSL1,LRIG1,ATP13A4,PARD3,BMPR1B,SLC1A3,GPM6A,SOX5,RYR3,RFX4,SLC1A2,NPAS3,AHCYL2,NKAIN3
2.248e-06	-13.01	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-acute_lymphoblastic_B_cell_leukaemia	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-acute_lymphoblastic_B_cell_leukaemia	3828	26	16828	48	RYR3,SLC1A2,SLC1A3,TNIK,ZBTB20,LSAMP,GLIS3,NFIA,ATP13A4,NRXN1,PCDH9,SOX5,GPM6A,HIF3A,RORA,NTM,NKAIN3,MEIS2,SLC4A4,COL5A3,GPC5,FBXL7,CTNND2,PARD3,BMPR1B,PAMR1
2.248e-06	-13.01	acute_lymphoblastic_B_cell_leukaemia	COSMIC cancer mutations	acute_lymphoblastic_B_cell_leukaemia	3828	26	16828	48	RYR3,SLC1A2,SLC1A3,TNIK,ZBTB20,NFIA,LSAMP,GLIS3,ATP13A4,PCDH9,NRXN1,SOX5,RORA,HIF3A,NTM,GPM6A,SLC4A4,NKAIN3,MEIS2,COL5A3,FBXL7,GPC5,CTNND2,BMPR1B,PARD3,PAMR1
2.797e-06	-12.79	L-aspartate transmembrane transport	biological process	GO:0070778	11	3	18204	48	SLC25A18,SLC1A2,SLC1A3
3.052e-06	-12.70	brainstem	COSMIC cancer mutations	brainstem	3102	23	16828	48	PARD3,GPC5,FBXL7,ZNRF3,CTNND2,NKAIN3,MEIS2,SOX5,FGFR3,GPM6A,RORA,ATP13A4,SFXN5,PCDH9,ZBTB20,LSAMP,CDH20,AHCYL2,RYR3,SLC1A2,NPAS3,SLC1A3,TNIK
3.778e-06	-12.49	multicellular organism development	biological process	GO:0007275	3957	25	18204	48	SLC1A3,NFIA,NRXN1,CTNNA2,CAMK2G,LRIG1,BMPR1B,PARD3,LSAMP,MEIS2,FGFR3,RFX4,ATP1A2,HIF3A,MSI2,TNIK,GPM6A,SOX5,CTNND2,PCDH9,ZNRF3,SLC1A2,CDH20,RORA,NTM
4.189e-06	-12.38	lymphoid_neoplasm	COSMIC cancer mutations	lymphoid_neoplasm	12233	47	16828	48	SLC1A2,RYR3,PARD3B,ACSS1,AHCYL2,LSAMP,PITPNC1,NFIA,SORBS1,PRODH,SFXN5,SPARCL1,GPM6A,SOX5,RFX4,MEIS2,NKAIN3,SLC4A4,ZNRF3,SLC25A18,CTNND2,CAMK2G,LRIG1,ATP1A2,BMPR1B,TNIK,SLC1A3,NPAS3,ABLIM1,DTNA,GLIS3,CDH20,MSI2,ZBTB20,NRXN1,PCDH9,ATP13A4,NTM,HIF3A,RORA,FGFR3,FBXL7,GPC5,COL5A3,PAMR1,NHSL1,PARD3
4.251e-06	-12.37	cell adhesion	biological process	GO:0007155	942	12	18204	48	PCDH9,NTM,SORBS1,CDH20,CTNNA2,CTNND2,NRXN1,LSAMP,COL5A3,PARD3,PARD3B,SPARCL1
5.860e-06	-12.05	L-glutamate transmembrane transporter activity	molecular function	GO:0005313	14	3	18094	47	SLC1A3,SLC25A18,SLC1A2
5.917e-06	-12.04	central_nervous_system-brain-primitive_neuroectodermal_tumour-medulloblastoma	COSMIC cancer mutations	central_nervous_system-brain-primitive_neuroectodermal_tumour-medulloblastoma	7205	36	16828	48	NFIA,GLIS3,PITPNC1,LSAMP,ZBTB20,SORBS1,PCDH9,NRXN1,ATP13A4,SFXN5,TNIK,SLC1A3,PARD3B,NPAS3,SLC1A2,RYR3,AHCYL2,ACSS1,ABLIM1,CTNND2,GPC5,FBXL7,COL5A3,NHSL1,PAMR1,PARD3,LRIG1,NTM,RORA,GPM6A,FGFR3,SOX5,RFX4,SLC4A4,MEIS2,NKAIN3
6.757e-06	-11.90	haematopoietic_and_lymphoid_tissue-lymph_node-lymphoid_neoplasm-mantle_cell_lymphoma	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue-lymph_node-lymphoid_neoplasm-mantle_cell_lymphoma	476	9	16828	48	LSAMP,GPM6A,CTNND2,RYR3,GPC5,PCDH9,MEIS2,ATP13A4,SFXN5
6.857e-06	-11.89	Par3/HAL_N	interpro domains	IPR021922	2	2	18521	49	PARD3B,PARD3
7.290e-06	-11.83	adherens junction	cellular component	GO:0005912	188	6	19108	48	CTNND2,CTNNA2,CDH20,SORBS1,PARD3,PARD3B
7.428e-06	-11.81	Par3_HAL_N_term	pfam domains	PF12053	2	2	17795	49	PARD3B,PARD3
7.580e-06	-11.79	system development	biological process	GO:0048731	3533	23	18204	48	NFIA,SLC1A3,CTNNA2,NRXN1,CAMK2G,LRIG1,BMPR1B,PARD3,LSAMP,MEIS2,HIF3A,ATP1A2,FGFR3,RFX4,MSI2,TNIK,GPM6A,SOX5,CTNND2,PCDH9,SLC1A2,NTM,RORA
7.613e-06	-11.79	haematopoietic_and_lymphoid_tissue-haematopoietic_neoplasm	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue-haematopoietic_neoplasm	764	11	16828	48	LSAMP,COL5A3,GPC5,FBXL7,PCDH9,ATP1A2,PARD3,SOX5,RYR3,SLC1A2,NKAIN3
7.671e-06	-11.78	central_nervous_system-brainstem-glioma-astrocytoma_Grade_IV	COSMIC cancer mutations	central_nervous_system-brainstem-glioma-astrocytoma_Grade_IV	2531	20	16828	48	RORA,TNIK,GPM6A,SLC1A3,SOX5,RYR3,AHCYL2,MEIS2,NKAIN3,CTNND2,CDH20,LSAMP,ZNRF3,GPC5,FBXL7,ZBTB20,PCDH9,PARD3,ATP13A4,SFXN5
8.945e-06	-11.62	upper_aerodigestive_tract-mouth-carcinoma-squamous_cell_carcinoma	COSMIC cancer mutations	upper_aerodigestive_tract-mouth-carcinoma-squamous_cell_carcinoma	6953	35	16828	48	TNIK,PARD3B,RYR3,SLC1A2,ABLIM1,ACSS1,DTNA,PITPNC1,CDH20,LSAMP,ZBTB20,NRXN1,PCDH9,SORBS1,ATP13A4,SFXN5,HIF3A,RORA,NTM,GPM6A,FGFR3,RFX4,SOX5,SLC4A4,CTNND2,SLC25A18,ZNRF3,GPC5,FBXL7,CAMK2G,NHSL1,PAMR1,PARD3,LRIG1,ATP1A2
9.792e-06	-11.53	cell morphogenesis	biological process	GO:0000902	687	10	18204	48	CDH20,BMPR1B,TNIK,NRXN1,CTNND2,CTNNA2,GPM6A,SLC1A3,NFIA,PARD3
1.209e-05	-11.32	mantle_cell_lymphoma	COSMIC cancer mutations	mantle_cell_lymphoma	2849	21	16828	48	FBXL7,GPC5,CTNND2,ZNRF3,LSAMP,PARD3,LRIG1,ATP13A4,SFXN5,PRODH,PCDH9,PARD3B,SOX5,RYR3,RFX4,SLC1A2,HIF3A,SLC1A3,GPM6A,NKAIN3,MEIS2
1.285e-05	-11.26	Transport of inorganic cations/anions and amino acids/oligopeptides	REACTOME pathways	R-HSA-425393	107	5	10285	30	SLC1A2,AHCYL2,SLC4A4,SLC1A3,SLC25A18
1.304e-05	-11.25	acidic amino acid transmembrane transporter activity	molecular function	GO:0015172	18	3	18094	47	SLC25A18,SLC1A2,SLC1A3
1.506e-05	-11.10	cell junction	cellular component	GO:0030054	2224	17	19108	48	SLC1A3,CTNND2,GPM6A,SORBS1,NRXN1,CTNNA2,SLC1A2,ATP1A2,CDH20,PARD3,DTNA,FGFR3,TNIK,NFIA,SPARCL1,PARD3B,PCDH9
1.557e-05	-11.07	PRNP (prion protein (Kanno blood group))	protein interactions	5621	1118	12	19454	49	MSI2,SPARCL1,ABLIM1,SLC1A3,LSAMP,GPM6A,SORBS1,SLC4A4,CAMK2G,AHCYL2,ATP1A2,NHSL1
1.589e-05	-11.05	anatomical structure development	biological process	GO:0048856	5207	28	18204	48	CAMK2G,BMPR1B,LRIG1,CTNNA2,NRXN1,COL5A3,NFIA,SLC1A3,MSI2,TNIK,ATP1A2,HIF3A,FGFR3,RFX4,LSAMP,MEIS2,PARD3,PCDH9,CTNND2,SPARCL1,ABLIM1,GPM6A,SOX5,CDH20,NTM,RORA,ZNRF3,SLC1A2
1.601e-05	-11.04	CTNNA1 (catenin alpha 1)	protein interactions	1495	325	7	19454	49	DTNA,SORBS1,CTNNA2,NHSL1,ABLIM1,TNIK,PARD3
1.840e-05	-10.90	MAPT (microtubule associated protein tau)	protein interactions	4137	948	11	19454	49	SLC1A2,CTNNA2,ATP1A2,ABLIM1,SORBS1,LSAMP,GPM6A,SLC1A3,CTNND2,TNIK,NTM
1.901e-05	-10.87	aspartate transmembrane transport	biological process	GO:0015810	20	3	18204	48	SLC1A3,SLC1A2,SLC25A18
2.528e-05	-10.59	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-mantle_cell_lymphoma	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-mantle_cell_lymphoma	2737	20	16828	48	PARD3,SFXN5,LRIG1,PCDH9,PRODH,FBXL7,GPC5,CTNND2,ZNRF3,LSAMP,MEIS2,NKAIN3,PARD3B,SLC1A2,RFX4,RYR3,SOX5,HIF3A,GPM6A,SLC1A3
2.865e-05	-10.46	anatomical structure morphogenesis	biological process	GO:0009653	2225	17	18204	48	LRIG1,BMPR1B,NRXN1,CTNND2,CTNNA2,GPM6A,SOX5,SLC1A3,NFIA,ABLIM1,CDH20,TNIK,RORA,FGFR3,HIF3A,MEIS2,PARD3
3.134e-05	-10.37	developmental process	biological process	GO:0032502	5716	29	18204	48	ZNRF3,SLC1A2,CDH20,NTM,RORA,ABLIM1,SPARCL1,SOX5,GPM6A,CTNND2,NHSL1,PCDH9,PARD3,LSAMP,MEIS2,HIF3A,ATP1A2,FGFR3,RFX4,MSI2,TNIK,NFIA,SLC1A3,COL5A3,CTNNA2,NRXN1,CAMK2G,LRIG1,BMPR1B
3.401e-05	-10.29	generation of neurons	biological process	GO:0048699	1158	12	18204	48	PARD3,NFIA,SLC1A3,GPM6A,SOX5,CTNNA2,CTNND2,NRXN1,TNIK,NTM,BMPR1B,RORA
3.748e-05	-10.19	cell-cell junction	cellular component	GO:0005911	513	8	19108	48	PARD3B,PCDH9,CDH20,ATP1A2,CTNNA2,PARD3,SORBS1,CTNND2
3.799e-05	-10.18	L-glutamate transmembrane transport	biological process	GO:0015813	25	3	18204	48	SLC1A3,SLC25A18,SLC1A2
4.287e-05	-10.06	C4-dicarboxylate transport	biological process	GO:0015740	26	3	18204	48	SLC1A3,SLC25A18,SLC1A2
4.787e-05	-9.95	multicellular organismal process	biological process	GO:0032501	6177	30	18204	48	TNIK,MSI2,HIF3A,ATP1A2,RFX4,FGFR3,RYR3,MEIS2,LSAMP,PARD3,LRIG1,BMPR1B,CAMK2G,CTNNA2,NRXN1,NFIA,SLC1A3,NTM,RORA,SLC4A4,CDH20,DTNA,SLC1A2,ZNRF3,PTGDS,PCDH9,CTNND2,ABLIM1,SOX5,GPM6A
4.917e-05	-9.92	Astrocytic Glutamate-Glutamine Uptake And Metabolism	REACTOME pathways	R-HSA-210455	4	2	10285	30	SLC1A2,SLC1A3
4.917e-05	-9.92	Neurotransmitter uptake and Metabolism In Glial Cells	REACTOME pathways	R-HSA-112313	4	2	10285	30	SLC1A2,SLC1A3
5.048e-05	-9.89	cerebellum	COSMIC cancer mutations	cerebellum	769	10	16828	48	ABLIM1,PCDH9,NRXN1,MEIS2,PARD3,CTNND2,RYR3,PARD3B,NPAS3,GPC5
5.724e-05	-9.77	amino acid:monoatomic cation symporter activity	molecular function	GO:0005416	29	3	18094	47	SLC1A3,SLC1A2,SLC25A18
5.769e-05	-9.76	upper_aerodigestive_tract-larynx-carcinoma-squamous_cell_carcinoma	COSMIC cancer mutations	upper_aerodigestive_tract-larynx-carcinoma-squamous_cell_carcinoma	1946	16	16828	48	PCDH9,NRXN1,BMPR1B,ZNRF3,COL5A3,ZBTB20,AHCYL2,SLC4A4,RORA,GPM6A,TNIK,NPAS3,PARD3B,FGFR3,RYR3,SOX5
5.842e-05	-9.75	larynx	COSMIC cancer mutations	larynx	1948	16	16828	48	AHCYL2,SLC4A4,GPM6A,TNIK,RORA,SOX5,RYR3,PARD3B,FGFR3,NPAS3,PCDH9,NRXN1,BMPR1B,ZNRF3,COL5A3,ZBTB20
5.891e-05	-9.74	acute_myeloid_leukaemia_therapy_related	COSMIC cancer mutations	acute_myeloid_leukaemia_therapy_related	1523	14	16828	48	COL5A3,GPC5,FBXL7,LSAMP,CTNND2,PARD3,PCDH9,RYR3,SOX5,SLC1A3,RORA,NKAIN3,MEIS2,ACSS1
5.891e-05	-9.74	haematopoietic_and_lymphoid_tissue-haematopoietic_neoplasm-acute_myeloid_leukaemia_therapy_related	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue-haematopoietic_neoplasm-acute_myeloid_leukaemia_therapy_related	1523	14	16828	48	SLC1A3,RORA,RYR3,SOX5,ACSS1,MEIS2,NKAIN3,LSAMP,CTNND2,FBXL7,GPC5,COL5A3,PCDH9,PARD3
6.518e-05	-9.64	oesophagus-carcinoma	COSMIC cancer mutations	oesophagus-carcinoma	4269	25	16828	48	TNIK,RYR3,PARD3B,ACSS1,CDH20,NFIA,ZBTB20,PRODH,PCDH9,SORBS1,ATP13A4,GPM6A,HIF3A,NTM,SOX5,RFX4,FGFR3,SLC4A4,CTNND2,COL5A3,FBXL7,PTGDS,NHSL1,LRIG1,PARD3
6.571e-05	-9.63	high-affinity L-glutamate transmembrane transporter activity	molecular function	GO:0005314	5	2	18094	47	SLC1A3,SLC1A2
6.571e-05	-9.63	glutamate:sodium symporter activity	molecular function	GO:0015501	5	2	18094	47	SLC1A2,SLC1A3
6.644e-05	-9.62	neurotransmitter uptake	biological process	GO:0001504	30	3	18204	48	SLC1A3,ATP1A2,SLC1A2
6.644e-05	-9.62	L-glutamate import	biological process	GO:0051938	30	3	18204	48	SLC1A3,SLC25A18,SLC1A2
6.774e-05	-9.60	D-aspartate import across plasma membrane	biological process	GO:0070779	5	2	18204	48	SLC1A2,SLC1A3
6.774e-05	-9.60	D-aspartate transmembrane transport	biological process	GO:0070777	5	2	18204	48	SLC1A3,SLC1A2
6.801e-05	-9.60	cell junction organization	biological process	GO:0034330	532	8	18204	48	SORBS1,CDH20,NRXN1,CTNND2,GPM6A,PARD3,SPARCL1,NFIA
7.279e-05	-9.53	active monoatomic ion transmembrane transporter activity	molecular function	GO:0022853	274	6	18094	47	ATP13A4,SLC1A3,SLC25A18,SLC1A2,ATP1A2,SLC4A4
7.360e-05	-9.52	right_upper_lobe	COSMIC cancer mutations	right_upper_lobe	10376	42	16828	48	ZBTB20,LSAMP,PITPNC1,CDH20,GLIS3,NFIA,ATP13A4,SFXN5,PRODH,NRXN1,PCDH9,SORBS1,RYR3,SLC1A2,NPAS3,PARD3B,SLC1A3,TNIK,DTNA,ABLIM1,AHCYL2,COL5A3,FBXL7,GPC5,ZNRF3,CTNND2,SLC25A18,LRIG1,ATP1A2,PARD3,BMPR1B,PAMR1,SOX5,RFX4,FGFR3,GPM6A,RORA,HIF3A,NTM,NKAIN3,MEIS2,SLC4A4
7.360e-05	-9.52	lung-right_upper_lobe-carcinoma-adenocarcinoma	COSMIC cancer mutations	lung-right_upper_lobe-carcinoma-adenocarcinoma	10376	42	16828	48	TNIK,SLC1A3,NPAS3,PARD3B,SLC1A2,RYR3,AHCYL2,ABLIM1,DTNA,NFIA,GLIS3,LSAMP,CDH20,PITPNC1,ZBTB20,SORBS1,NRXN1,PCDH9,PRODH,ATP13A4,SFXN5,NTM,RORA,HIF3A,GPM6A,FGFR3,RFX4,SOX5,SLC4A4,MEIS2,NKAIN3,SLC25A18,CTNND2,ZNRF3,GPC5,FBXL7,COL5A3,PAMR1,BMPR1B,PARD3,ATP1A2,LRIG1
7.526e-05	-9.49	pharynx	COSMIC cancer mutations	pharynx	2696	19	16828	48	ATP13A4,SFXN5,ATP1A2,NHSL1,SORBS1,PCDH9,PRODH,GPC5,CTNND2,NFIA,PITPNC1,DTNA,SLC4A4,PARD3B,NPAS3,FGFR3,SLC1A2,RFX4,RYR3
7.709e-05	-9.47	vascular transport	biological process	GO:0010232	86	4	18204	48	ATP1A2,SLC1A3,SLC1A2,SLC4A4
7.709e-05	-9.47	transport across blood-brain barrier	biological process	GO:0150104	86	4	18204	48	SLC1A2,SLC4A4,ATP1A2,SLC1A3
7.769e-05	-9.46	NTM (neurotrimin)	protein interactions	50863	33	3	19454	49	GPM6A,LSAMP,NTM
8.151e-05	-9.41	central_nervous_system-cerebellum-primitive_neuroectodermal_tumour-medulloblastoma-SHH_subtype	COSMIC cancer mutations	central_nervous_system-cerebellum-primitive_neuroectodermal_tumour-medulloblastoma-SHH_subtype	653	9	16828	48	ABLIM1,NRXN1,PCDH9,PARD3,MEIS2,CTNND2,PARD3B,NPAS3,RYR3
8.239e-05	-9.40	neuron projection	cellular component	GO:0043005	1331	12	19108	48	CTNNA2,AHCYL2,ATP1A2,CAMK2G,SLC1A2,SLC1A3,GPM6A,CTNND2,PCDH9,DTNA,PARD3,BMPR1B
8.247e-05	-9.40	SHH_subtype	COSMIC cancer mutations	SHH_subtype	654	9	16828	48	MEIS2,PARD3,ABLIM1,PCDH9,NRXN1,RYR3,NPAS3,PARD3B,CTNND2
8.880e-05	-9.33	response to auditory stimulus	biological process	GO:0010996	33	3	18204	48	ATP1A2,NRXN1,SLC1A3
8.970e-05	-9.32	Transmembrane transport of small molecules	REACTOME pathways	R-HSA-382551	677	9	10285	30	ATP13A4,SLC1A2,RYR3,SLC25A18,ATP1A2,AHCYL2,CAMK2G,SLC4A4,SLC1A3
9.104e-05	-9.30	neuron differentiation	biological process	GO:0030182	1081	11	18204	48	BMPR1B,CTNNA2,CTNND2,NRXN1,NFIA,SLC1A3,GPM6A,NTM,RORA,TNIK,PARD3
1.014e-04	-9.20	L-aspartate import across plasma membrane	biological process	GO:0140009	6	2	18204	48	SLC1A3,SLC1A2
1.014e-04	-9.20	D-amino acid transport	biological process	GO:0042940	6	2	18204	48	SLC1A3,SLC1A2
1.101e-04	-9.11	cell periphery	cellular component	GO:0071944	6020	28	19108	48	SLC4A4,PARD3,DTNA,LRIG1,TNIK,SPARCL1,PCDH9,SLC1A3,CTNND2,NRXN1,ZNRF3,NKAIN3,FGFR3,BMPR1B,PARD3B,RYR3,GPC5,HIF3A,SORBS1,GPM6A,NTM,CDH20,ATP1A2,SLC1A2,COL5A3,ATP13A4,CTNNA2,LSAMP
1.162e-04	-9.06	monoatomic ion transmembrane transporter activity	molecular function	GO:0015075	752	9	18094	47	ATP13A4,SLC25A18,ATP1A2,RYR3,GPM6A,SFXN5,SLC1A2,SLC1A3,SLC4A4
1.336e-04	-8.92	neurogenesis	biological process	GO:0022008	1334	12	18204	48	PARD3,RORA,TNIK,NTM,NFIA,SLC1A3,GPM6A,SOX5,CTNNA2,CTNND2,NRXN1,BMPR1B
1.402e-04	-8.87	humerus	COSMIC cancer mutations	humerus	546	8	16828	48	GPM6A,HIF3A,SOX5,PARD3B,GPC5,AHCYL2,NKAIN3,SFXN5
1.428e-04	-8.85	Na-dicarboxylate_symporter_CS	interpro domains	IPR018107	7	2	18521	49	SLC1A2,SLC1A3
1.428e-04	-8.85	Na:dicarbo_symporter_sf	interpro domains	IPR036458	7	2	18521	49	SLC1A2,SLC1A3
1.428e-04	-8.85	Na-dicarboxylate_symporter	interpro domains	IPR001991	7	2	18521	49	SLC1A3,SLC1A2
1.471e-04	-8.82	cellular response to alkaloid	biological process	GO:0071312	39	3	18204	48	SLC1A2,SLC1A3,RYR3
1.477e-04	-8.82	TIAM1 (TIAM Rac1 associated GEF 1)	protein interactions	7074	201	5	19454	49	RYR3,PARD3,CAMK2G,ATP1A2,DTNA
1.546e-04	-8.77	SDF	pfam domains	PF00375	7	2	17795	49	SLC1A2,SLC1A3
1.695e-04	-8.68	beta-catenin binding	molecular function	GO:0008013	107	4	18094	47	RORA,CTNNA2,CDH20,CTNND2
1.729e-04	-8.66	bone-tibia-other-chondroblastoma	COSMIC cancer mutations	bone-tibia-other-chondroblastoma	98	4	16828	48	NKAIN3,CTNND2,LSAMP,GPM6A
1.794e-04	-8.63	Sodium:dicarboxylate symporter	gene3d domains	1.10.3860.10	7	2	14470	43	SLC1A2,SLC1A3
1.955e-04	-8.54	monoatomic cation transmembrane transporter activity	molecular function	GO:0008324	630	8	18094	47	SLC4A4,GPM6A,SLC1A2,SLC1A3,ATP1A2,RYR3,ATP13A4,SLC25A18
2.018e-04	-8.51	mouth	COSMIC cancer mutations	mouth	9004	38	16828	48	DTNA,ACSS1,ABLIM1,SLC1A2,RYR3,NPAS3,PARD3B,TNIK,SLC1A3,SFXN5,ATP13A4,PCDH9,SORBS1,NRXN1,ZBTB20,LSAMP,PITPNC1,CDH20,SLC4A4,SOX5,RFX4,FGFR3,GPM6A,NTM,RORA,HIF3A,LRIG1,ATP1A2,PARD3,PAMR1,NHSL1,CAMK2G,GPC5,FBXL7,COL5A3,ZNRF3,SLC25A18,CTNND2
2.033e-04	-8.50	bone-humerus-other-chondroblastoma	COSMIC cancer mutations	bone-humerus-other-chondroblastoma	301	6	16828	48	SOX5,GPC5,GPM6A,NKAIN3,SFXN5,AHCYL2
2.175e-04	-8.43	monoatomic ion transmembrane transport	biological process	GO:0034220	804	9	18204	48	SFXN5,SLC4A4,ATP1A2,ATP13A4,RYR3,SLC1A2,SLC25A18,SLC1A3,GPM6A
2.204e-04	-8.42	plasma membrane	cellular component	GO:0005886	5538	26	19108	48	SORBS1,GPM6A,ATP1A2,NTM,CDH20,ATP13A4,SLC1A2,LSAMP,CTNNA2,NKAIN3,FGFR3,BMPR1B,PARD3B,RYR3,HIF3A,GPC5,SLC1A3,CTNND2,NRXN1,ZNRF3,SLC4A4,PARD3,DTNA,LRIG1,TNIK,PCDH9
2.212e-04	-8.42	LSAMP (limbic system associated membrane protein)	protein interactions	4045	9	2	19454	49	NTM,LSAMP
2.212e-04	-8.42	NEGR1 (neuronal growth regulator 1)	protein interactions	257194	9	2	19454	49	NTM,LSAMP
2.259e-04	-8.40	acidic amino acid transport	biological process	GO:0015800	45	3	18204	48	SLC1A3,SLC1A2,SLC25A18
2.267e-04	-8.39	autonomic_ganglia	COSMIC cancer mutations	autonomic_ganglia	4005	23	16828	48	GPM6A,HIF3A,RFX4,FGFR3,SLC4A4,ZNRF3,CTNND2,CAMK2G,COL5A3,FBXL7,NHSL1,ATP1A2,PARD3,TNIK,RYR3,SLC1A2,PARD3B,NPAS3,ACSS1,PITPNC1,GLIS3,NFIA,PCDH9
2.329e-04	-8.37	EDTRNSPORT	prints domains	PR00173	7	2	5227	18	SLC1A3,SLC1A2
2.390e-04	-8.34	solute:monoatomic cation symporter activity	molecular function	GO:0015294	117	4	18094	47	SLC4A4,SLC1A3,SLC25A18,SLC1A2
2.526e-04	-8.28	NA_DICARBOXYL_SYMP_2	prosite domains	PS00714	7	2	12186	43	SLC1A2,SLC1A3
2.526e-04	-8.28	NA_DICARBOXYL_SYMP_1	prosite domains	PS00713	7	2	12186	43	SLC1A2,SLC1A3
2.642e-04	-8.24	neuron projection morphogenesis	biological process	GO:0048812	486	7	18204	48	GPM6A,PARD3,BMPR1B,TNIK,NRXN1,CTNNA2,CTNND2
2.647e-04	-8.24	blood_vessel	COSMIC cancer mutations	blood_vessel	2211	16	16828	48	FBXL7,GPC5,COL5A3,CTNND2,LSAMP,CDH20,PARD3,PCDH9,FGFR3,SLC1A2,SOX5,RYR3,GPM6A,SLC1A3,MEIS2,NKAIN3
2.812e-04	-8.18	plasma membrane bounded cell projection morphogenesis	biological process	GO:0120039	491	7	18204	48	GPM6A,PARD3,NRXN1,CTNND2,CTNNA2,BMPR1B,TNIK
2.990e-04	-8.12	cell projection morphogenesis	biological process	GO:0048858	496	7	18204	48	NRXN1,CTNND2,CTNNA2,BMPR1B,TNIK,GPM6A,PARD3
3.023e-04	-8.10	establishment of centrosome localization	biological process	GO:0051660	10	2	18204	48	PARD3,PARD3B
3.023e-04	-8.10	cellular response to cocaine	biological process	GO:0071314	10	2	18204	48	SLC1A2,SLC1A3
3.550e-04	-7.94	neuron development	biological process	GO:0048666	859	9	18204	48	SLC1A3,GPM6A,PARD3,NTM,BMPR1B,TNIK,NRXN1,CTNNA2,CTNND2
3.564e-04	-7.94	anchoring junction	cellular component	GO:0070161	902	9	19108	48	FGFR3,PARD3,SORBS1,CTNND2,PARD3B,CDH20,ATP1A2,PCDH9,CTNNA2
3.648e-04	-7.92	Bicarbonate transporters	REACTOME pathways	R-HSA-425381	10	2	10285	30	SLC4A4,AHCYL2
3.688e-04	-7.91	L-glutamate import across plasma membrane	biological process	GO:0098712	11	2	18204	48	SLC1A2,SLC1A3
3.972e-04	-7.83	diffuse_large_B_cell_lymphoma	COSMIC cancer mutations	diffuse_large_B_cell_lymphoma	4151	23	16828	48	RYR3,SLC1A2,SLC1A3,TNIK,DTNA,ACSS1,AHCYL2,LSAMP,CDH20,SPARCL1,ATP13A4,PCDH9,SOX5,FGFR3,GPM6A,RORA,NKAIN3,MEIS2,FBXL7,GPC5,CTNND2,ATP1A2,PARD3
3.975e-04	-7.83	NAKATPASE	prints domains	PR00121	9	2	5227	18	ATP13A4,ATP1A2
4.014e-04	-7.82	amino acid transport	biological process	GO:0006865	132	4	18204	48	SLC1A2,SLC25A18,SFXN5,SLC1A3
4.074e-04	-7.81	Ig_I-set	interpro domains	IPR013098	132	4	18521	49	LRIG1,FGFR3,LSAMP,NTM
4.325e-04	-7.75	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-diffuse_large_B_cell_lymphoma	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-diffuse_large_B_cell_lymphoma	3608	21	16828	48	PCDH9,ATP13A4,ATP1A2,SPARCL1,PARD3,CDH20,LSAMP,CTNND2,GPC5,FBXL7,ACSS1,AHCYL2,MEIS2,NKAIN3,GPM6A,TNIK,RORA,SLC1A2,RYR3,SOX5,FGFR3
4.418e-04	-7.72	auditory behavior	biological process	GO:0031223	12	2	18204	48	NRXN1,SLC1A3
4.447e-04	-7.72	cell body	cellular component	GO:0044297	556	7	19108	48	SLC1A3,NRXN1,SLC1A2,ATP1A2,BMPR1B,GPM6A,CTNND2
4.456e-04	-7.72	carcinoid-endocrine_tumour	COSMIC cancer mutations	carcinoid-endocrine_tumour	7752	34	16828	48	SLC25A18,CTNND2,GPC5,FBXL7,COL5A3,CAMK2G,NHSL1,PAMR1,BMPR1B,PARD3,ATP1A2,LRIG1,RORA,GPM6A,FGFR3,SOX5,RFX4,SLC4A4,MEIS2,NKAIN3,GLIS3,CDH20,LSAMP,PCDH9,PRODH,ATP13A4,SFXN5,TNIK,SLC1A3,SLC1A2,RYR3,AHCYL2,ACSS1,ABLIM1
4.555e-04	-7.69	visual behavior	biological process	GO:0007632	57	3	18204	48	SLC1A2,MEIS2,ATP1A2
4.733e-04	-7.66	I-set	pfam domains	PF07679	132	4	17795	49	LSAMP,NTM,FGFR3,LRIG1
4.983e-04	-7.60	bone	COSMIC cancer mutations	bone	8157	35	16828	48	PARD3,LRIG1,ATP1A2,PTGDS,PAMR1,GPC5,COL5A3,CAMK2G,CTNND2,SLC4A4,NKAIN3,FGFR3,SOX5,RORA,HIF3A,GPM6A,SFXN5,ATP13A4,SPARCL1,NRXN1,PCDH9,SORBS1,PRODH,ZBTB20,GLIS3,LSAMP,DTNA,AHCYL2,ACSS1,ABLIM1,NPAS3,PARD3B,RYR3,TNIK,SLC1A3
5.015e-04	-7.60	neurotransmitter transport	biological process	GO:0006836	140	4	18204	48	SLC1A2,NRXN1,SLC1A3,ATP1A2
5.547e-04	-7.50	DACT2 (dishevelled binding antagonist of beta catenin 2)	protein interactions	168002	14	2	19454	49	CAMK2G,ZBTB20
5.593e-04	-7.49	Ion homeostasis	REACTOME pathways	R-HSA-5578775	56	3	10285	30	CAMK2G,RYR3,ATP1A2
5.833e-04	-7.45	symporter activity	molecular function	GO:0015293	148	4	18094	47	SLC4A4,SLC1A2,SLC25A18,SLC1A3
5.887e-04	-7.44	autonomic_ganglia-neuroblastoma	COSMIC cancer mutations	autonomic_ganglia-neuroblastoma	3970	22	16828	48	PARD3,ATP1A2,PCDH9,COL5A3,FBXL7,CAMK2G,CTNND2,NFIA,PITPNC1,ZNRF3,GLIS3,SLC4A4,ACSS1,PARD3B,FGFR3,NPAS3,RYR3,RFX4,SLC1A2,HIF3A,TNIK,GPM6A
5.909e-04	-7.43	neuroblastoma	COSMIC cancer mutations	neuroblastoma	3971	22	16828	48	ACSS1,TNIK,PARD3B,NPAS3,RYR3,SLC1A2,PCDH9,NFIA,PITPNC1,GLIS3,SLC4A4,HIF3A,GPM6A,FGFR3,RFX4,PARD3,ATP1A2,CTNND2,ZNRF3,COL5A3,FBXL7,CAMK2G
6.069e-04	-7.41	Ig_3	pfam domains	PF13927	141	4	17795	49	LRIG1,FGFR3,NTM,LSAMP
6.071e-04	-7.41	mechanosensory behavior	biological process	GO:0007638	14	2	18204	48	NRXN1,SLC1A3
6.071e-04	-7.41	sodium ion export across plasma membrane	biological process	GO:0036376	14	2	18204	48	SLC4A4,ATP1A2
6.202e-04	-7.39	Ion transport by P-type ATPases	REACTOME pathways	R-HSA-936837	58	3	10285	30	CAMK2G,ATP13A4,ATP1A2
6.337e-04	-7.36	organic anion transmembrane transporter activity	molecular function	GO:0008514	268	5	18094	47	SLC1A3,SLC1A2,SLC25A18,SFXN5,SLC4A4
6.391e-04	-7.36	TIAM2 (TIAM Rac1 associated GEF 2)	protein interactions	26230	15	2	19454	49	PARD3,TNIK
6.702e-04	-7.31	L-amino acid transmembrane transporter activity	molecular function	GO:0015179	66	3	18094	47	SLC25A18,SLC1A2,SLC1A3
7.006e-04	-7.26	L-alpha-amino acid transmembrane transport	biological process	GO:1902475	66	3	18204	48	SLC1A3,SLC25A18,SLC1A2
7.454e-04	-7.20	sodium ion transmembrane transporter activity	molecular function	GO:0015081	158	4	18094	47	SLC4A4,ATP1A2,SLC1A2,SLC1A3
7.583e-04	-7.18	inorganic cation transmembrane transporter activity	molecular function	GO:0022890	589	7	18094	47	SLC25A18,SLC1A2,SLC1A3,GPM6A,RYR3,SLC4A4,ATP1A2
7.767e-04	-7.16	human chr3q13.31	chromosome location	human chr3q13.31	22	2	26134	49	ZBTB20,LSAMP
7.955e-04	-7.14	FGFR1 (fibroblast growth factor receptor 1)	protein interactions	2260	611	7	19454	49	TNIK,PARD3,FGFR3,DTNA,AHCYL2,NHSL1,ABLIM1
7.979e-04	-7.13	asymmetric cell division	biological process	GO:0008356	16	2	18204	48	SOX5,PARD3
8.042e-04	-7.13	upper_aerodigestive_tract	COSMIC cancer mutations	upper_aerodigestive_tract	13181	46	16828	48	HIF3A,RORA,NTM,FGFR3,PAMR1,NHSL1,PARD3,COL5A3,FBXL7,GPC5,ABLIM1,DTNA,SLC1A3,TNIK,NPAS3,PCDH9,NRXN1,ATP13A4,CDH20,GLIS3,ZBTB20,MSI2,NKAIN3,SLC4A4,GPM6A,SOX5,RFX4,PTGDS,LRIG1,ATP1A2,BMPR1B,ZNRF3,CTNND2,SLC25A18,CAMK2G,ACSS1,AHCYL2,RYR3,SLC1A2,PARD3B,PRODH,SORBS1,SFXN5,PITPNC1,LSAMP,NFIA
8.060e-04	-7.12	soft_tissue-blood_vessel-angiosarcoma	COSMIC cancer mutations	soft_tissue-blood_vessel-angiosarcoma	2192	15	16828	48	PARD3,PCDH9,FBXL7,GPC5,COL5A3,CTNND2,CDH20,LSAMP,MEIS2,NKAIN3,SLC1A2,SOX5,RYR3,GPM6A,SLC1A3
8.060e-04	-7.12	angiosarcoma	COSMIC cancer mutations	angiosarcoma	2192	15	16828	48	CTNND2,CDH20,LSAMP,FBXL7,GPC5,COL5A3,PCDH9,PARD3,GPM6A,SLC1A3,SLC1A2,RYR3,SOX5,MEIS2,NKAIN3
8.180e-04	-7.11	monoatomic ion transport	biological process	GO:0006811	964	9	18204	48	ATP13A4,RYR3,ATP1A2,SFXN5,SLC4A4,SLC1A3,GPM6A,SLC25A18,SLC1A2
8.233e-04	-7.10	pancreas-carcinoid-endocrine_tumour	COSMIC cancer mutations	pancreas-carcinoid-endocrine_tumour	7250	32	16828	48	ATP1A2,LRIG1,BMPR1B,PARD3,PAMR1,NHSL1,COL5A3,GPC5,FBXL7,CTNND2,SLC25A18,NKAIN3,MEIS2,SLC4A4,SOX5,RFX4,FGFR3,GPM6A,RORA,SFXN5,ATP13A4,PRODH,PCDH9,CDH20,LSAMP,GLIS3,ABLIM1,ACSS1,AHCYL2,RYR3,SLC1A2,SLC1A3
8.536e-04	-7.07	lung-carcinoma-small_cell_carcinoma	COSMIC cancer mutations	lung-carcinoma-small_cell_carcinoma	9908	39	16828	48	PCDH9,SORBS1,NRXN1,PRODH,ATP13A4,SPARCL1,PITPNC1,CDH20,NFIA,MSI2,ABLIM1,AHCYL2,DTNA,TNIK,RYR3,PARD3B,NPAS3,PAMR1,ATP1A2,LRIG1,PARD3,BMPR1B,ZNRF3,SLC25A18,CTNND2,CAMK2G,FBXL7,GPC5,COL5A3,MEIS2,NKAIN3,SLC4A4,GPM6A,NTM,RORA,HIF3A,SOX5,RFX4,FGFR3
8.608e-04	-7.06	response to endogenous stimulus	biological process	GO:0009719	1402	11	18204	48	SOX5,SLC1A3,NFIA,BMPR1B,SORBS1,PTGDS,SLC1A2,MEIS2,FGFR3,RYR3,ATP1A2
8.653e-04	-7.05	small_cell_carcinoma	COSMIC cancer mutations	small_cell_carcinoma	9913	39	16828	48	SLC4A4,NKAIN3,MEIS2,HIF3A,RORA,NTM,GPM6A,FGFR3,RFX4,SOX5,PAMR1,BMPR1B,PARD3,ATP1A2,LRIG1,CTNND2,SLC25A18,ZNRF3,COL5A3,FBXL7,GPC5,CAMK2G,AHCYL2,ABLIM1,DTNA,TNIK,NPAS3,PARD3B,RYR3,PRODH,NRXN1,SORBS1,PCDH9,SPARCL1,ATP13A4,NFIA,PITPNC1,CDH20,MSI2
8.967e-04	-7.02	cell junction assembly	biological process	GO:0034329	285	5	18204	48	SORBS1,CDH20,PARD3,NRXN1,GPM6A
9.218e-04	-6.99	transporter activity	molecular function	GO:0005215	1211	10	18094	47	SLC25A18,ATP13A4,RYR3,ATP1A2,SLC1A3,SLC1A2,SFXN5,GPM6A,PITPNC1,SLC4A4
9.267e-04	-6.98	NECTIN1 (nectin cell adhesion molecule 1)	protein interactions	5818	18	2	19454	49	FGFR3,PARD3
9.444e-04	-6.96	metal ion transmembrane transporter activity	molecular function	GO:0046873	442	6	18094	47	SLC4A4,RYR3,ATP1A2,SLC1A3,SLC1A2,GPM6A
9.636e-04	-6.94	Htt (huntingtin)	protein interactions	15194	77	3	19454	49	NTM,LSAMP,GPM6A
9.667e-04	-6.94	active transmembrane transporter activity	molecular function	GO:0022804	444	6	18094	47	SLC25A18,SLC1A2,SLC1A3,ATP13A4,SLC4A4,ATP1A2
9.828e-04	-6.93	Adherens junction	KEGG pathways	hsa04520	72	3	7161	20	SORBS1,CTNNA2,PARD3
9.828e-04	-6.93	Adherens junction	KEGG pathways	ko04520	72	3	7161	20	SORBS1,CTNNA2,PARD3
1.000e-03	-6.91	ANKRD40 (ankyrin repeat domain 40)	protein interactions	91369	78	3	19454	49	SOX5,SLC25A18,MSI2
1.021e-03	-6.89	ATPase_P-typ_cation-transptr_N	interpro domains	IPR004014	18	2	18521	49	ATP1A2,ATP13A4
1.024e-03	-6.88	central nervous system development	biological process	GO:0007417	995	9	18204	48	MEIS2,SLC1A2,PCDH9,MSI2,BMPR1B,RORA,ATP1A2,CTNNA2,RFX4
1.037e-03	-6.87	cell morphogenesis involved in neuron differentiation	biological process	GO:0048667	443	6	18204	48	BMPR1B,NRXN1,CTNND2,CTNNA2,SLC1A3,PARD3
1.068e-03	-6.84	C11orf52 (chromosome 11 open reading frame 52)	protein interactions	91894	310	5	19454	49	ABLIM1,TNIK,DTNA,AHCYL2,PARD3
1.085e-03	-6.83	EPHA4 (EPH receptor A4)	protein interactions	2043	180	4	19454	49	FGFR3,CTNNA2,PARD3,AHCYL2
1.091e-03	-6.82	plasma membrane region	cellular component	GO:0098590	1278	10	19108	48	SORBS1,GPM6A,TNIK,SLC1A3,SLC4A4,PARD3,SLC1A2,ATP1A2,PARD3B,NRXN1
1.105e-03	-6.81	Cation_ATPase_N	pfam domains	PF00690	18	2	17795	49	ATP13A4,ATP1A2
1.107e-03	-6.81	cartilage development	biological process	GO:0051216	173	4	18204	48	BMPR1B,FGFR3,SOX5,NFIA
1.131e-03	-6.78	cartilage condensation	biological process	GO:0001502	19	2	18204	48	SOX5,BMPR1B
1.139e-03	-6.78	PAS_fold	interpro domains	IPR013767	19	2	18521	49	HIF3A,NPAS3
1.139e-03	-6.78	positive regulation of carbohydrate metabolic process	biological process	GO:0045913	78	3	18204	48	ZBTB20,SLC4A4,SORBS1
1.139e-03	-6.78	dicarboxylic acid transport	biological process	GO:0006835	78	3	18204	48	SLC1A3,SLC25A18,SLC1A2
1.147e-03	-6.77	PDZD2 (PDZ domain containing 2)	protein interactions	23037	20	2	19454	49	NRXN1,CTNND2
1.160e-03	-6.76	right_lower_lobe	COSMIC cancer mutations	right_lower_lobe	5692	27	16828	48	SLC1A3,NPAS3,PARD3B,RYR3,AHCYL2,DTNA,LSAMP,CDH20,SORBS1,PRODH,ATP13A4,NTM,GPM6A,SOX5,SLC4A4,MEIS2,NKAIN3,SLC25A18,CTNND2,ZNRF3,GPC5,FBXL7,COL5A3,PAMR1,PARD3,ATP1A2,LRIG1
1.160e-03	-6.76	lung-right_lower_lobe-carcinoma-adenocarcinoma	COSMIC cancer mutations	lung-right_lower_lobe-carcinoma-adenocarcinoma	5692	27	16828	48	SLC1A3,RYR3,PARD3B,NPAS3,AHCYL2,DTNA,LSAMP,CDH20,SORBS1,PRODH,ATP13A4,GPM6A,NTM,SOX5,MEIS2,NKAIN3,SLC4A4,ZNRF3,SLC25A18,CTNND2,GPC5,FBXL7,COL5A3,PAMR1,ATP1A2,LRIG1,PARD3
1.173e-03	-6.75	solute:sodium symporter activity	molecular function	GO:0015370	80	3	18094	47	SLC1A3,SLC1A2,SLC4A4
1.203e-03	-6.72	Axon guidance	KEGG pathways	hsa04360	174	4	7161	20	ABLIM1,CAMK2G,PARD3,BMPR1B
1.203e-03	-6.72	Axon guidance	KEGG pathways	ko04360	174	4	7161	20	ABLIM1,BMPR1B,PARD3,CAMK2G
1.224e-03	-6.71	cervix-carcinoma-squamous_cell_carcinoma	COSMIC cancer mutations	cervix-carcinoma-squamous_cell_carcinoma	11789	43	16828	48	NPAS3,PARD3B,SLC1A2,RYR3,TNIK,SLC1A3,DTNA,ACSS1,ABLIM1,ZBTB20,NFIA,GLIS3,CDH20,LSAMP,PITPNC1,ATP13A4,SFXN5,SPARCL1,NRXN1,SORBS1,PCDH9,PRODH,FGFR3,SOX5,RFX4,NTM,RORA,HIF3A,GPM6A,SLC4A4,MEIS2,FBXL7,GPC5,COL5A3,SLC25A18,CTNND2,ZNRF3,BMPR1B,PARD3,LRIG1,ATP1A2,NHSL1,PAMR1
1.233e-03	-6.70	PAS	pfam domains	PF00989	19	2	17795	49	NPAS3,HIF3A
1.238e-03	-6.69	cervix	COSMIC cancer mutations	cervix	11793	43	16828	48	FBXL7,GPC5,COL5A3,PAMR1,NHSL1,PARD3,NTM,RORA,HIF3A,FGFR3,GLIS3,CDH20,ZBTB20,NRXN1,PCDH9,ATP13A4,TNIK,SLC1A3,NPAS3,ABLIM1,DTNA,ZNRF3,SLC25A18,CTNND2,ATP1A2,LRIG1,BMPR1B,GPM6A,RFX4,SOX5,MEIS2,SLC4A4,LSAMP,PITPNC1,NFIA,SORBS1,PRODH,SFXN5,SPARCL1,SLC1A2,RYR3,PARD3B,ACSS1
1.255e-03	-6.68	positive regulation of chondrocyte differentiation	biological process	GO:0032332	20	2	18204	48	BMPR1B,SOX5
1.302e-03	-6.64	monoatomic cation transmembrane transport	biological process	GO:0098655	636	7	18204	48	SLC4A4,RYR3,ATP13A4,ATP1A2,SLC25A18,GPM6A,SLC1A3
1.313e-03	-6.64	SLC-mediated transmembrane transport	REACTOME pathways	R-HSA-425407	287	5	10285	30	SLC1A3,SLC25A18,SLC4A4,AHCYL2,SLC1A2
1.337e-03	-6.62	lung-carcinoma-squamous_cell_carcinoma	COSMIC cancer mutations	lung-carcinoma-squamous_cell_carcinoma	14664	48	16828	48	FBXL7,GPC5,COL5A3,PARD3,PAMR1,NHSL1,FGFR3,NTM,HIF3A,RORA,MSI2,ZBTB20,GLIS3,CDH20,ATP13A4,NRXN1,PCDH9,NPAS3,TNIK,SLC1A3,DTNA,ABLIM1,CAMK2G,ZNRF3,SLC25A18,CTNND2,LRIG1,ATP1A2,BMPR1B,PTGDS,RFX4,SOX5,GPM6A,MEIS2,NKAIN3,SLC4A4,PITPNC1,LSAMP,NFIA,SFXN5,SPARCL1,SORBS1,PRODH,SLC1A2,RYR3,PARD3B,ACSS1,AHCYL2
1.344e-03	-6.61	neuronal cell body	cellular component	GO:0043025	489	6	19108	48	GPM6A,CTNND2,BMPR1B,SLC1A3,ATP1A2,NRXN1
1.362e-03	-6.60	regulation of carbohydrate metabolic process	biological process	GO:0006109	183	4	18204	48	SLC4A4,RORA,SORBS1,ZBTB20
1.366e-03	-6.60	carboxylic acid transmembrane transporter activity	molecular function	GO:0046943	186	4	18094	47	SLC1A2,SLC25A18,SLC1A3,SFXN5
1.385e-03	-6.58	cell aggregation	biological process	GO:0098743	21	2	18204	48	SOX5,BMPR1B
1.385e-03	-6.58	positive regulation of nucleotide catabolic process	biological process	GO:0030813	21	2	18204	48	SLC4A4,ZBTB20
1.385e-03	-6.58	positive regulation of glycolytic process	biological process	GO:0045821	21	2	18204	48	ZBTB20,SLC4A4
1.385e-03	-6.58	positive regulation of purine nucleotide catabolic process	biological process	GO:0033123	21	2	18204	48	ZBTB20,SLC4A4
1.393e-03	-6.58	organic acid transmembrane transporter activity	molecular function	GO:0005342	187	4	18094	47	SLC1A3,SLC25A18,SLC1A2,SFXN5
1.411e-03	-6.56	L-amino acid transport	biological process	GO:0015807	84	3	18204	48	SLC25A18,SLC1A2,SLC1A3
1.460e-03	-6.53	chondrocyte differentiation	biological process	GO:0002062	85	3	18204	48	FGFR3,SOX5,BMPR1B
1.465e-03	-6.53	Cation_ATPase_N	smart domains	SM00831	16	2	9717	35	ATP13A4,ATP1A2
1.520e-03	-6.49	TIMM10B (translocase of inner mitochondrial membrane 10B)	protein interactions	26515	23	2	19454	49	MSI2,MEIS2
1.521e-03	-6.49	intracellular sodium ion homeostasis	biological process	GO:0006883	22	2	18204	48	ATP1A2,SLC1A3
1.614e-03	-6.43	amino acid:sodium symporter activity	molecular function	GO:0005283	23	2	18094	47	SLC1A3,SLC1A2
1.720e-03	-6.37	CASK (calcium/calmodulin dependent serine protein kinase)	protein interactions	8573	204	4	19454	49	ABLIM1,NRXN1,DTNA,PARD3B
1.724e-03	-6.36	scalp	COSMIC cancer mutations	scalp	2110	14	16828	48	ATP1A2,ATP13A4,SORBS1,NRXN1,COL5A3,GPC5,CAMK2G,NFIA,LSAMP,SLC4A4,FGFR3,SOX5,RORA,NTM
1.731e-03	-6.36	oesophagus-carcinoma-squamous_cell_carcinoma	COSMIC cancer mutations	oesophagus-carcinoma-squamous_cell_carcinoma	6486	29	16828	48	SLC4A4,MEIS2,FGFR3,SOX5,HIF3A,GPM6A,PARD3,BMPR1B,ATP1A2,GPC5,FBXL7,COL5A3,SLC25A18,CTNND2,ABLIM1,NPAS3,PARD3B,RYR3,TNIK,SFXN5,ATP13A4,SPARCL1,NRXN1,SORBS1,PCDH9,PRODH,ZBTB20,GLIS3,PITPNC1
1.732e-03	-6.36	soft_tissue	COSMIC cancer mutations	soft_tissue	5828	27	16828	48	SLC1A2,RYR3,PARD3B,NPAS3,SLC1A3,GLIS3,LSAMP,CDH20,NFIA,SPARCL1,PCDH9,SORBS1,SOX5,FGFR3,GPM6A,RORA,MEIS2,NKAIN3,CAMK2G,FBXL7,GPC5,COL5A3,ZNRF3,CTNND2,PARD3,PAMR1,NHSL1
1.742e-03	-6.35	cell projection	cellular component	GO:0042995	2398	14	19108	48	GPM6A,CTNND2,ABLIM1,SLC1A3,CTNNA2,AHCYL2,ATP1A2,CAMK2G,SLC1A2,NRXN1,BMPR1B,PARD3,DTNA,PCDH9
1.757e-03	-6.34	P-type transmembrane transporter activity	molecular function	GO:0140358	24	2	18094	47	ATP13A4,ATP1A2
1.757e-03	-6.34	P-type ion transporter activity	molecular function	GO:0015662	24	2	18094	47	ATP13A4,ATP1A2
1.786e-03	-6.33	synapse organization	biological process	GO:0050808	333	5	18204	48	SPARCL1,NFIA,CTNND2,GPM6A,NRXN1
1.810e-03	-6.31	Proximal tubule bicarbonate reclamation	KEGG pathways	hsa04964	23	2	7161	20	SLC4A4,ATP1A2
1.810e-03	-6.31	Proximal tubule bicarbonate reclamation	KEGG pathways	ko04964	23	2	7161	20	ATP1A2,SLC4A4
1.863e-03	-6.29	nasopharyngeal_carcinoma	COSMIC cancer mutations	nasopharyngeal_carcinoma	1425	11	16828	48	NHSL1,ATP1A2,SFXN5,ATP13A4,SLC4A4,PITPNC1,NFIA,CTNND2,RFX4,SLC1A2,FGFR3
1.863e-03	-6.29	upper_aerodigestive_tract-pharynx-carcinoma-nasopharyngeal_carcinoma	COSMIC cancer mutations	upper_aerodigestive_tract-pharynx-carcinoma-nasopharyngeal_carcinoma	1425	11	16828	48	NFIA,CTNND2,PITPNC1,NHSL1,SFXN5,ATP13A4,ATP1A2,FGFR3,SLC1A2,RFX4,SLC4A4
1.875e-03	-6.28	human chr15q13.3-q14	chromosome location	human chr15q13.3-q14	1	1	26134	49	RYR3
1.875e-03	-6.28	human chr10p11.22-p11.21	chromosome location	human chr10p11.22-p11.21	1	1	26134	49	PARD3
1.875e-03	-6.28	human chr3q26.2-q26.31	chromosome location	human chr3q26.2-q26.31	1	1	26134	49	TNIK
1.931e-03	-6.25	FRS2 (fibroblast growth factor receptor substrate 2)	protein interactions	10818	98	3	19454	49	FGFR3,PARD3,SORBS1
1.959e-03	-6.24	transmembrane transporter activity	molecular function	GO:0022857	1110	9	18094	47	ATP13A4,SLC25A18,ATP1A2,RYR3,SFXN5,GPM6A,SLC1A2,SLC1A3,SLC4A4
2.028e-03	-6.20	extrinsic component of plasma membrane	cellular component	GO:0019897	100	3	19108	48	CTNNA2,CDH20,DTNA
2.055e-03	-6.19	haematopoietic_neoplasm	COSMIC cancer mutations	haematopoietic_neoplasm	11082	41	16828	48	DTNA,AHCYL2,ABLIM1,ACSS1,PARD3B,NPAS3,RYR3,SLC1A2,SLC1A3,TNIK,SPARCL1,ATP13A4,SFXN5,PRODH,NRXN1,PCDH9,MSI2,NFIA,LSAMP,CDH20,GLIS3,SLC4A4,NKAIN3,MEIS2,FGFR3,RFX4,SOX5,RORA,HIF3A,NTM,BMPR1B,PARD3,ATP1A2,LRIG1,NHSL1,PAMR1,COL5A3,FBXL7,GPC5,CAMK2G,CTNND2
2.095e-03	-6.17	KCNJ12 (potassium inwardly rectifying channel subfamily J member 12)	protein interactions	3768	27	2	19454	49	ABLIM1,DTNA
2.126e-03	-6.15	neuron projection development	biological process	GO:0031175	693	7	18204	48	PARD3,GPM6A,CTNNA2,CTNND2,NRXN1,BMPR1B,TNIK
2.132e-03	-6.15	amino acid transmembrane transport	biological process	GO:0003333	97	3	18204	48	SLC1A3,SLC25A18,SLC1A2
2.164e-03	-6.14	KRTAP6-1 (keratin associated protein 6-1)	protein interactions	337966	102	3	19454	49	GLIS3,CAMK2G,MEIS2
2.181e-03	-6.13	Glutamate Neurotransmitter Release Cycle	REACTOME pathways	R-HSA-210500	24	2	10285	30	SLC1A2,SLC1A3
2.227e-03	-6.11	amino acid transmembrane transporter activity	molecular function	GO:0015171	100	3	18094	47	SLC1A2,SLC25A18,SLC1A3
2.253e-03	-6.10	LRRC7 (leucine rich repeat containing 7)	protein interactions	57554	28	2	19454	49	CAMK2G,CTNND2
2.287e-03	-6.08	HUNK (hormonally up-regulated Neu-associated kinase)	protein interactions	30811	104	3	19454	49	SORBS1,SPARCL1,ABLIM1
2.299e-03	-6.08	inorganic molecular entity transmembrane transporter activity	molecular function	GO:0015318	714	7	18094	47	ATP1A2,RYR3,SLC25A18,SLC4A4,GPM6A,SLC1A2,SLC1A3
2.312e-03	-6.07	tibia	COSMIC cancer mutations	tibia	836	8	16828	48	FGFR3,CTNND2,LSAMP,TNIK,GPM6A,NKAIN3,ABLIM1,ACSS1
2.325e-03	-6.06	response to alkaloid	biological process	GO:0043279	100	3	18204	48	SLC1A3,RYR3,SLC1A2
2.375e-03	-6.04	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-chronic_lymphocytic_leukaemia-small_lymphocytic_lymphoma	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-chronic_lymphocytic_leukaemia-small_lymphocytic_lymphoma	3511	19	16828	48	DTNA,SLC4A4,MEIS2,NPAS3,PARD3B,RYR3,TNIK,SLC1A3,BMPR1B,PARD3,PCDH9,PAMR1,GPC5,FBXL7,MSI2,CTNND2,LSAMP,PITPNC1,ZNRF3
2.375e-03	-6.04	chronic_lymphocytic_leukaemia-small_lymphocytic_lymphoma	COSMIC cancer mutations	chronic_lymphocytic_leukaemia-small_lymphocytic_lymphoma	3511	19	16828	48	BMPR1B,PARD3,PAMR1,PCDH9,GPC5,FBXL7,MSI2,CTNND2,ZNRF3,LSAMP,PITPNC1,SLC4A4,DTNA,MEIS2,PARD3B,NPAS3,RYR3,SLC1A3,TNIK
2.416e-03	-6.03	INSC (INSC spindle orientation adaptor protein)	protein interactions	387755	29	2	19454	49	PARD3B,PARD3
2.478e-03	-6.00	Calcium-transporting ATPase, transmembrane domain	gene3d domains	1.20.1110.10	25	2	14470	43	ATP1A2,ATP13A4
2.519e-03	-5.98	Agtrap (angiotensin II, type I receptor-associated protein)	protein interactions	11610	1	1	19454	49	PITPNC1
2.519e-03	-5.98	Lztr1 (leucine-zipper-like transcriptional regulator, 1)	protein interactions	66863	1	1	19454	49	BMPR1B
2.519e-03	-5.98	Dcaf7 (DDB1 and CUL4 associated factor 7)	protein interactions	71833	1	1	19454	49	BMPR1B
2.519e-03	-5.98	Isl1 (ISL1 transcription factor, LIM/homeodomain)	protein interactions	16392	1	1	19454	49	GLIS3
2.519e-03	-5.98	Sh2b1 (SH2B adaptor protein 1)	protein interactions	20399	1	1	19454	49	FGFR3
2.519e-03	-5.98	fgf3.L (fibroblast growth factor 3 L homeolog)	protein interactions	373669	1	1	19454	49	FGFR3
2.519e-03	-5.98	1700006A11Rik (RIKEN cDNA 1700006A11 gene)	protein interactions	71824	1	1	19454	49	BMPR1B
2.519e-03	-5.98	Hipk3 (homeodomain interacting protein kinase 3)	protein interactions	15259	1	1	19454	49	GLIS3
2.519e-03	-5.98	Sytl1 (synaptotagmin-like 1)	protein interactions	269589	1	1	19454	49	NRXN1
2.548e-03	-5.97	cellular response to endogenous stimulus	biological process	GO:0071495	1135	9	18204	48	SLC1A2,NFIA,SOX5,SLC1A3,BMPR1B,SORBS1,ATP1A2,FGFR3,RYR3
2.626e-03	-5.94	YWHAB (tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein beta)	protein interactions	7529	965	8	19454	49	PARD3,PITPNC1,FGFR3,PARD3B,CAMK2G,SORBS1,NHSL1,ABLIM1
2.637e-03	-5.94	negative regulation of calcium:sodium antiporter activity	biological process	GO:1903280	1	1	18204	48	ATP1A2
2.637e-03	-5.94	olfactory cortex development	biological process	GO:0021989	1	1	18204	48	ATP1A2
2.646e-03	-5.93	SORBS1_SH3_2	interpro domains	IPR035611	1	1	18521	49	SORBS1
2.646e-03	-5.93	SORBS1_SH3	interpro domains	IPR035606	1	1	18521	49	SORBS1
2.646e-03	-5.93	SPARC-like_p1	interpro domains	IPR016359	1	1	18521	49	SPARCL1
2.646e-03	-5.93	SORBS1_SH3_1	interpro domains	IPR035610	1	1	18521	49	SORBS1
2.646e-03	-5.93	ZNRF3_Znf_RING	interpro domains	IPR045903	1	1	18521	49	ZNRF3
2.664e-03	-5.93	response to mechanical stimulus	biological process	GO:0009612	220	4	18204	48	MEIS2,SLC1A3,NRXN1,ATP1A2
2.671e-03	-5.93	neural precursor cell proliferation	biological process	GO:0061351	105	3	18204	48	NFIA,SOX5,RORA
2.706e-03	-5.91	thyroid-carcinoma	COSMIC cancer mutations	thyroid-carcinoma	4126	21	16828	48	TNIK,HIF3A,SOX5,RYR3,FGFR3,ACSS1,DTNA,GLIS3,LSAMP,ZNRF3,CTNND2,NFIA,GPC5,COL5A3,NRXN1,PCDH9,ATP13A4,LRIG1,SPARCL1,ATP1A2,PARD3
2.719e-03	-5.91	brain development	biological process	GO:0007420	724	7	18204	48	RFX4,CTNNA2,ATP1A2,RORA,PCDH9,MEIS2,SLC1A2
2.743e-03	-5.90	catenin complex	cellular component	GO:0016342	31	2	19108	48	CDH20,CTNNA2
2.749e-03	-5.90	Muscle contraction	REACTOME pathways	R-HSA-397014	204	4	10285	30	ATP1A2,CAMK2G,SORBS1,RYR3
2.754e-03	-5.89	FGFR3_TM	pfam domains	PF21165	1	1	17795	49	FGFR3
2.817e-03	-5.87	plasma membrane bounded cell projection organization	biological process	GO:0120036	1152	9	18204	48	GPM6A,ABLIM1,PARD3,RFX4,NRXN1,CTNND2,CTNNA2,TNIK,BMPR1B
2.917e-03	-5.84	t(4;14) translocations of FGFR3	REACTOME pathways	R-HSA-2033515	1	1	10285	30	FGFR3
2.937e-03	-5.83	NXPH2 (neurexophilin 2)	protein interactions	11249	32	2	19454	49	PCDH9,NRXN1
2.972e-03	-5.82	-	gene3d domains	6.10.250.1740	1	1	14470	43	FGFR3
2.983e-03	-5.81	cell-cell adhesion	biological process	GO:0098609	546	6	18204	48	CDH20,PCDH9,NRXN1,CTNNA2,CTNND2,SPARCL1
2.985e-03	-5.81	skin-leg-malignant_melanoma-superficial_spreading	COSMIC cancer mutations	skin-leg-malignant_melanoma-superficial_spreading	210	4	16828	48	NTM,ATP13A4,SLC4A4,COL5A3
3.000e-03	-5.81	Ion channel transport	REACTOME pathways	R-HSA-983712	209	4	10285	30	ATP13A4,ATP1A2,CAMK2G,RYR3
3.024e-03	-5.80	nodular	COSMIC cancer mutations	nodular	1515	11	16828	48	SPARCL1,ATP1A2,ATP13A4,CTNND2,CDH20,GLIS3,SLC4A4,ABLIM1,NPAS3,FGFR3,HIF3A
3.042e-03	-5.80	SMAD7 (SMAD family member 7)	protein interactions	4092	115	3	19454	49	SOX5,PARD3,BMPR1B
3.098e-03	-5.78	human chr11p13	chromosome location	human chr11p13	44	2	26134	49	PAMR1,SLC1A2
3.127e-03	-5.77	urinary_tract-bladder-carcinoma-transitional_cell_carcinoma	COSMIC cancer mutations	urinary_tract-bladder-carcinoma-transitional_cell_carcinoma	6040	27	16828	48	ZBTB20,GLIS3,CDH20,NFIA,SFXN5,ATP13A4,SPARCL1,PCDH9,NRXN1,SORBS1,PRODH,PARD3B,SLC1A3,DTNA,ACSS1,ABLIM1,CAMK2G,GPC5,COL5A3,ATP1A2,LRIG1,PARD3,RFX4,FGFR3,GPM6A,HIF3A,SLC4A4
3.143e-03	-5.76	transitional_cell_carcinoma	COSMIC cancer mutations	transitional_cell_carcinoma	6042	27	16828	48	ZBTB20,GLIS3,CDH20,NFIA,ATP13A4,SFXN5,SPARCL1,PCDH9,NRXN1,SORBS1,PRODH,PARD3B,SLC1A3,DTNA,ACSS1,ABLIM1,CAMK2G,GPC5,COL5A3,LRIG1,ATP1A2,PARD3,RFX4,FGFR3,GPM6A,HIF3A,SLC4A4
3.145e-03	-5.76	large_intestine-caecum-carcinoma-adenocarcinoma	COSMIC cancer mutations	large_intestine-caecum-carcinoma-adenocarcinoma	14236	47	16828	48	PARD3B,RYR3,SLC1A2,AHCYL2,ACSS1,NFIA,LSAMP,PITPNC1,SPARCL1,SFXN5,PRODH,SORBS1,SOX5,RFX4,GPM6A,SLC4A4,NKAIN3,MEIS2,CAMK2G,CTNND2,SLC25A18,ZNRF3,BMPR1B,ATP1A2,LRIG1,PTGDS,NPAS3,SLC1A3,TNIK,DTNA,ABLIM1,ZBTB20,CDH20,GLIS3,ATP13A4,NRXN1,PCDH9,FGFR3,HIF3A,RORA,NTM,COL5A3,FBXL7,GPC5,PARD3,NHSL1,PAMR1
3.175e-03	-5.75	upper_leg	COSMIC cancer mutations	upper_leg	880	8	16828	48	HIF3A,NFIA,GLIS3,FGFR3,PAMR1,ACSS1,PCDH9,LRIG1
3.211e-03	-5.74	microtubule organizing center localization	biological process	GO:0061842	32	2	18204	48	PARD3B,PARD3
3.211e-03	-5.74	positive regulation of cartilage development	biological process	GO:0061036	32	2	18204	48	BMPR1B,SOX5
3.211e-03	-5.74	positive regulation of ATP metabolic process	biological process	GO:1903580	32	2	18204	48	SLC4A4,ZBTB20
3.211e-03	-5.74	centrosome localization	biological process	GO:0051642	32	2	18204	48	PARD3,PARD3B
3.211e-03	-5.74	transepithelial transport	biological process	GO:0070633	32	2	18204	48	SLC1A2,SLC1A3
3.224e-03	-5.74	connective tissue development	biological process	GO:0061448	232	4	18204	48	NFIA,SOX5,FGFR3,BMPR1B
3.259e-03	-5.73	caecum	COSMIC cancer mutations	caecum	14248	47	16828	48	GLIS3,CDH20,ZBTB20,PCDH9,NRXN1,ATP13A4,TNIK,SLC1A3,NPAS3,ABLIM1,DTNA,GPC5,FBXL7,COL5A3,NHSL1,PAMR1,PARD3,NTM,RORA,HIF3A,FGFR3,NFIA,PITPNC1,LSAMP,SORBS1,PRODH,SFXN5,SPARCL1,PARD3B,SLC1A2,RYR3,AHCYL2,ACSS1,SLC25A18,CTNND2,ZNRF3,CAMK2G,PTGDS,BMPR1B,ATP1A2,LRIG1,GPM6A,SOX5,RFX4,SLC4A4,MEIS2,NKAIN3
3.282e-03	-5.72	E1-E2_ATPase	pfam domains	PF00122	31	2	17795	49	ATP1A2,ATP13A4
3.350e-03	-5.70	plasma membrane bounded cell projection	cellular component	GO:0120025	2285	13	19108	48	DTNA,PARD3,BMPR1B,PCDH9,SLC1A3,CTNND2,GPM6A,ABLIM1,CTNNA2,AHCYL2,ATP1A2,CAMK2G,SLC1A2
3.495e-03	-5.66	Cation_ATPase	pfam domains	PF13246	32	2	17795	49	ATP13A4,ATP1A2
3.590e-03	-5.63	PAS	smart domains	SM00091	25	2	9717	35	NPAS3,HIF3A
3.622e-03	-5.62	upper_aerodigestive_tract-mouth-carcinoma	COSMIC cancer mutations	upper_aerodigestive_tract-mouth-carcinoma	6426	28	16828	48	ABLIM1,ACSS1,PARD3B,NPAS3,RYR3,SLC1A2,SLC1A3,SFXN5,SORBS1,ZBTB20,PITPNC1,CDH20,SLC4A4,FGFR3,SOX5,RFX4,RORA,HIF3A,NTM,GPM6A,PARD3,NHSL1,PAMR1,COL5A3,GPC5,FBXL7,CTNND2,SLC25A18
3.635e-03	-5.62	Ig_sub2	interpro domains	IPR003598	239	4	18521	49	LRIG1,FGFR3,NTM,LSAMP
3.644e-03	-5.61	PAS-like_dom_sf	interpro domains	IPR035965	34	2	18521	49	NPAS3,HIF3A
3.644e-03	-5.61	PAS	interpro domains	IPR000014	34	2	18521	49	HIF3A,NPAS3
3.702e-03	-5.60	cell projection organization	biological process	GO:0030030	1200	9	18204	48	BMPR1B,TNIK,CTNNA2,CTNND2,RFX4,NRXN1,PARD3,ABLIM1,GPM6A
3.707e-03	-5.60	SLC5A5 (solute carrier family 5 member 5)	protein interactions	6528	36	2	19454	49	SFXN5,CAMK2G
3.717e-03	-5.59	monoatomic cation transport	biological process	GO:0006812	766	7	18204	48	SLC25A18,SLC1A3,GPM6A,SLC4A4,ATP1A2,ATP13A4,RYR3
3.721e-03	-5.59	organic acid:sodium symporter activity	molecular function	GO:0005343	35	2	18094	47	SLC1A2,SLC1A3
3.854e-03	-5.56	organic anion transport	biological process	GO:0015711	398	5	18204	48	SLC1A3,SFXN5,SLC4A4,SLC25A18,SLC1A2
3.893e-03	-5.55	striated muscle contraction	biological process	GO:0006941	120	3	18204	48	RYR3,ATP1A2,DTNA
3.913e-03	-5.54	BCAT2 (branched chain amino acid transaminase 2)	protein interactions	587	37	2	19454	49	PRODH,PTGDS
3.936e-03	-5.54	head development	biological process	GO:0060322	774	7	18204	48	MEIS2,SLC1A2,RFX4,ATP1A2,CTNNA2,RORA,PCDH9
4.021e-03	-5.52	EPB41L4A (erythrocyte membrane protein band 4.1 like 4A)	protein interactions	64097	127	3	19454	49	ABLIM1,PARD3,DTNA
4.048e-03	-5.51	intracellular chemical homeostasis	biological process	GO:0055082	581	6	18204	48	ATP1A2,ATP13A4,RYR3,ZBTB20,SLC4A4,SLC1A3
4.079e-03	-5.50	ATPase_P-typ_cyto_dom_N	interpro domains	IPR023299	36	2	18521	49	ATP13A4,ATP1A2
4.079e-03	-5.50	P_typ_ATPase	interpro domains	IPR001757	36	2	18521	49	ATP13A4,ATP1A2
4.079e-03	-5.50	ATPase_P-typ_P_site	interpro domains	IPR018303	36	2	18521	49	ATP1A2,ATP13A4
4.079e-03	-5.50	ATPase_P-typ_transduc_dom_A_sf	interpro domains	IPR008250	36	2	18521	49	ATP1A2,ATP13A4
4.079e-03	-5.50	P_typ_ATPase_HD_dom	interpro domains	IPR044492	36	2	18521	49	ATP1A2,ATP13A4
4.196e-03	-5.47	central_nervous_system-brainstem-glioma-oligoastrocytoma_Grade_III	COSMIC cancer mutations	central_nervous_system-brainstem-glioma-oligoastrocytoma_Grade_III	114	3	16828	48	SLC1A2,SOX5,RYR3
4.275e-03	-5.45	positive regulation of purine nucleotide metabolic process	biological process	GO:1900544	37	2	18204	48	ZBTB20,SLC4A4
4.275e-03	-5.45	positive regulation of glucose import	biological process	GO:0046326	37	2	18204	48	SORBS1,SLC1A2
4.275e-03	-5.45	positive regulation of nucleotide metabolic process	biological process	GO:0045981	37	2	18204	48	SLC4A4,ZBTB20
4.305e-03	-5.45	ATPase_P-typ_TM_dom_sf	interpro domains	IPR023298	37	2	18521	49	ATP1A2,ATP13A4
4.432e-03	-5.42	L-proline degradation	BIOCYC pathways	META_PROUT-PWY	2	1	902	2	PRODH
4.505e-03	-5.40	amino acid import across plasma membrane	biological process	GO:0089718	38	2	18204	48	SLC1A2,SLC1A3
4.561e-03	-5.39	DZIP1 (DAZ interacting zinc finger protein 1)	protein interactions	22873	40	2	19454	49	CAMK2G,PARD3
4.574e-03	-5.39	RHOB (ras homolog family member B)	protein interactions	388	832	7	19454	49	ABLIM1,AHCYL2,DTNA,PARD3B,SLC1A3,PARD3,TNIK
4.639e-03	-5.37	haematopoietic_and_lymphoid_tissue	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue	14368	47	16828	48	NRXN1,PCDH9,ATP13A4,CDH20,GLIS3,ZBTB20,MSI2,ABLIM1,DTNA,SLC1A3,TNIK,NPAS3,NHSL1,PAMR1,PARD3,COL5A3,GPC5,FBXL7,HIF3A,RORA,NTM,FGFR3,PRODH,SORBS1,SPARCL1,SFXN5,NFIA,LSAMP,PITPNC1,AHCYL2,ACSS1,PARD3B,RYR3,SLC1A2,BMPR1B,ATP1A2,LRIG1,CTNND2,SLC25A18,ZNRF3,CAMK2G,SLC4A4,NKAIN3,MEIS2,GPM6A,RFX4,SOX5
4.741e-03	-5.35	sodium ion homeostasis	biological process	GO:0055078	39	2	18204	48	ATP1A2,SLC1A3
4.770e-03	-5.35	NTRK2 (neurotrophic receptor tyrosine kinase 2)	protein interactions	4915	135	3	19454	49	ABLIM1,PARD3,DTNA
4.896e-03	-5.32	stomach-carcinoma-intestinal_adenocarcinoma	COSMIC cancer mutations	stomach-carcinoma-intestinal_adenocarcinoma	7225	30	16828	48	ACSS1,NPAS3,PARD3B,SLC1A2,RYR3,NRXN1,PCDH9,PRODH,SFXN5,ATP13A4,NFIA,LSAMP,PITPNC1,CDH20,ZBTB20,SLC4A4,MEIS2,NTM,RORA,FGFR3,RFX4,SOX5,NHSL1,PARD3,ATP1A2,LRIG1,CTNND2,ZNRF3,FBXL7,COL5A3
4.896e-03	-5.32	intestinal_adenocarcinoma	COSMIC cancer mutations	intestinal_adenocarcinoma	7225	30	16828	48	NFIA,PITPNC1,LSAMP,CDH20,ZBTB20,PCDH9,NRXN1,PRODH,ATP13A4,SFXN5,NPAS3,PARD3B,SLC1A2,RYR3,ACSS1,CTNND2,ZNRF3,FBXL7,COL5A3,NHSL1,PARD3,ATP1A2,LRIG1,NTM,RORA,FGFR3,RFX4,SOX5,SLC4A4,MEIS2
4.955e-03	-5.31	oligoastrocytoma_Grade_II	COSMIC cancer mutations	oligoastrocytoma_Grade_II	121	3	16828	48	FGFR3,DTNA,CDH20
4.969e-03	-5.30	PAS	prosite domains	PS50112	30	2	12186	43	NPAS3,HIF3A
4.974e-03	-5.30	carboxylic acid transmembrane transport	biological process	GO:1905039	131	3	18204	48	SLC1A3,SLC25A18,SLC1A2
5.031e-03	-5.29	Kdm4c (lysine (K)-specific demethylase 4C)	protein interactions	76804	2	1	19454	49	GLIS3
5.031e-03	-5.29	Zmym2 (zinc finger, MYM-type 2)	protein interactions	76007	2	1	19454	49	GLIS3
5.031e-03	-5.29	Bmpr2 (bone morphogenetic protein receptor type 2)	protein interactions	12168	2	1	19454	49	BMPR1B
5.031e-03	-5.29	Bcr (BCR activator of RhoGEF and GTPase)	protein interactions	110279	2	1	19454	49	BMPR1B
5.031e-03	-5.29	Klhl1 (kelch-like 1)	protein interactions	93688	2	1	19454	49	BMPR1B
5.031e-03	-5.29	SLC23A3 (solute carrier family 23 member 3)	protein interactions	151295	2	1	19454	49	PRODH
5.031e-03	-5.29	Fkbp1a (FK506 binding protein 1a)	protein interactions	14225	2	1	19454	49	BMPR1B
5.031e-03	-5.29	Fkbp1b (FK506 binding protein 1b)	protein interactions	14226	2	1	19454	49	BMPR1B
5.031e-03	-5.29	Sh3kbp1 (SH3-domain kinase binding protein 1)	protein interactions	58194	2	1	19454	49	BMPR1B
5.031e-03	-5.29	Mknk2 (MAP kinase-interacting serine/threonine kinase 2)	protein interactions	17347	2	1	19454	49	BMPR1B
5.031e-03	-5.29	Ppp3cc (protein phosphatase 3, catalytic subunit, gamma isoform)	protein interactions	19057	2	1	19454	49	BMPR1B
5.031e-03	-5.29	Fbxo34 (F-box protein 34)	protein interactions	78938	2	1	19454	49	BMPR1B
5.031e-03	-5.29	Irf7 (interferon regulatory factor 7)	protein interactions	54123	2	1	19454	49	BMPR1B
5.078e-03	-5.28	animal organ development	biological process	GO:0048513	2846	15	18204	48	MEIS2,SLC1A2,RFX4,FGFR3,ATP1A2,RORA,SOX5,GPM6A,NFIA,ABLIM1,COL5A3,CTNNA2,BMPR1B,LRIG1,PCDH9
5.097e-03	-5.28	Calcium-transporting ATPase, cytoplasmic domain N	gene3d domains	3.40.1110.10	36	2	14470	43	ATP13A4,ATP1A2
5.097e-03	-5.28	Calcium-transporting ATPase, cytoplasmic transduction domain A	gene3d domains	2.70.150.10	36	2	14470	43	ATP1A2,ATP13A4
5.188e-03	-5.26	proline dehydrogenase activity	molecular function	GO:0004657	2	1	18094	47	PRODH
5.210e-03	-5.26	transmembrane transport	biological process	GO:0055085	1264	9	18204	48	SLC1A2,SLC25A18,GPM6A,SLC1A3,SLC4A4,SFXN5,ATP1A2,RYR3,ATP13A4
5.225e-03	-5.25	sarcoplasmic reticulum membrane	cellular component	GO:0033017	43	2	19108	48	RYR3,CAMK2G
5.236e-03	-5.25	intracellular monoatomic cation homeostasis	biological process	GO:0030003	428	5	18204	48	SLC4A4,RYR3,SLC1A3,ATP13A4,ATP1A2
5.267e-03	-5.25	acetate biosynthetic process	biological process	GO:0019413	2	1	18204	48	ACSS1
5.267e-03	-5.25	acetyl-CoA biosynthetic process from acetate	biological process	GO:0019427	2	1	18204	48	ACSS1
5.267e-03	-5.25	Wnt receptor catabolic process	biological process	GO:0038018	2	1	18204	48	ZNRF3
5.267e-03	-5.25	propionate biosynthetic process	biological process	GO:0019542	2	1	18204	48	ACSS1
5.267e-03	-5.25	fibroblast growth factor receptor apoptotic signaling pathway	biological process	GO:1902178	2	1	18204	48	FGFR3
5.284e-03	-5.24	Ac_CoA_lig	interpro domains	IPR011904	2	1	18521	49	ACSS1
5.284e-03	-5.24	MSI_RRM2	interpro domains	IPR034126	2	1	18521	49	MSI2
5.284e-03	-5.24	Osteonectin_CS	interpro domains	IPR001999	2	1	18521	49	SPARCL1
5.284e-03	-5.24	Proline_oxidase	interpro domains	IPR015659	2	1	18521	49	PRODH
5.284e-03	-5.24	ZNRF-3_ecto	interpro domains	IPR040700	2	1	18521	49	ZNRF3
5.284e-03	-5.24	Proline_DH_dom	interpro domains	IPR002872	2	1	18521	49	PRODH
5.284e-03	-5.24	Distrobrevin	interpro domains	IPR017432	2	1	18521	49	DTNA
5.322e-03	-5.24	neutral L-amino acid transmembrane transporter activity	molecular function	GO:0015175	42	2	18094	47	SLC1A3,SLC1A2
5.390e-03	-5.22	haematopoietic_and_lymphoid_tissue-haematopoietic_neoplasm-mast_cell_neoplasm	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue-haematopoietic_neoplasm-mast_cell_neoplasm	248	4	16828	48	NPAS3,GPC5,PCDH9,NFIA
5.390e-03	-5.22	mast_cell_neoplasm	COSMIC cancer mutations	mast_cell_neoplasm	248	4	16828	48	PCDH9,NFIA,NPAS3,GPC5
5.407e-03	-5.22	organic acid transmembrane transport	biological process	GO:1903825	135	3	18204	48	SLC1A3,SLC1A2,SLC25A18
5.443e-03	-5.21	sarcolemma	cellular component	GO:0042383	142	3	19108	48	DTNA,RYR3,ATP1A2
5.457e-03	-5.21	inorganic cation transmembrane transport	biological process	GO:0098662	618	6	18204	48	SLC1A3,GPM6A,SLC25A18,ATP1A2,RYR3,SLC4A4
5.500e-03	-5.20	ZNRF_3_ecto	pfam domains	PF18212	2	1	17795	49	ZNRF3
5.500e-03	-5.20	Pro_dh	pfam domains	PF01619	2	1	17795	49	PRODH
5.501e-03	-5.20	FLOT1 (flotillin 1)	protein interactions	10211	453	5	19454	49	ABLIM1,SOX5,PARD3,SORBS1,DTNA
5.514e-03	-5.20	axon	cellular component	GO:0030424	650	6	19108	48	DTNA,PARD3,GPM6A,CTNNA2,PCDH9,SLC1A2
5.603e-03	-5.18	LCK (LCK proto-oncogene, Src family tyrosine kinase)	protein interactions	3932	455	5	19454	49	SLC25A18,CTNND2,DTNA,CAMK2G,PARD3
5.706e-03	-5.17	Calml3 (calmodulin-like 3)	protein interactions	70405	144	3	19454	49	CAMK2G,ZBTB20,ABLIM1
5.712e-03	-5.17	intracellular monoatomic ion homeostasis	biological process	GO:0006873	437	5	18204	48	ATP1A2,RYR3,SLC1A3,ATP13A4,SLC4A4
5.737e-03	-5.16	vascular process in circulatory system	biological process	GO:0003018	273	4	18204	48	SLC1A3,ATP1A2,SLC4A4,SLC1A2
5.747e-03	-5.16	regulation of generation of precursor metabolites and energy	biological process	GO:0043467	138	3	18204	48	ZBTB20,SLC4A4,SORBS1
5.826e-03	-5.15	Proline catabolism	REACTOME pathways	R-HSA-70688	2	1	10285	30	PRODH
5.836e-03	-5.14	PARD3 (par-3 family cell polarity regulator)	protein interactions	56288	287	4	19454	49	PARD3B,DTNA,PARD3,SORBS1
5.935e-03	-5.13	Vinculin, Vh2 four-helix bundle	gene3d domains	1.20.120.810	2	1	14470	43	CTNNA2
5.935e-03	-5.13	-	gene3d domains	6.20.350.10	2	1	14470	43	RYR3
5.946e-03	-5.12	spleen	COSMIC cancer mutations	spleen	408	5	16828	48	PARD3B,MEIS2,NTM,SORBS1,TNIK
5.967e-03	-5.12	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm	7307	30	16828	48	AHCYL2,ABLIM1,ACSS1,SLC1A3,TNIK,PARD3B,RYR3,SLC1A2,PCDH9,SPARCL1,ATP13A4,SFXN5,CDH20,LSAMP,GLIS3,NKAIN3,MEIS2,RORA,GPM6A,RFX4,SOX5,NHSL1,PAMR1,BMPR1B,PARD3,LRIG1,CTNND2,COL5A3,FBXL7,GPC5
5.997e-03	-5.12	prostate	COSMIC cancer mutations	prostate	13883	46	16828	48	ZNRF3,SLC25A18,CTNND2,LRIG1,ATP1A2,BMPR1B,GPM6A,SOX5,RFX4,MEIS2,NKAIN3,SLC4A4,PITPNC1,LSAMP,NFIA,SORBS1,PRODH,SFXN5,SPARCL1,SLC1A2,RYR3,PARD3B,ACSS1,AHCYL2,FBXL7,GPC5,COL5A3,PAMR1,NHSL1,PARD3,NTM,HIF3A,RORA,FGFR3,GLIS3,CDH20,MSI2,ZBTB20,PCDH9,NRXN1,ATP13A4,TNIK,SLC1A3,NPAS3,ABLIM1,DTNA
6.002e-03	-5.12	positive regulation of glucose transmembrane transport	biological process	GO:0010828	44	2	18204	48	SLC1A2,SORBS1
6.041e-03	-5.11	MOB4 (MOB family member 4, phocein)	protein interactions	25843	147	3	19454	49	ABLIM1,CAMK2G,TNIK
6.075e-03	-5.10	lung-carcinoma-adenocarcinoma	COSMIC cancer mutations	lung-carcinoma-adenocarcinoma	15133	48	16828	48	RORA,HIF3A,NTM,FGFR3,COL5A3,GPC5,FBXL7,NHSL1,PAMR1,PARD3,SLC1A3,TNIK,NPAS3,ABLIM1,DTNA,CDH20,GLIS3,ZBTB20,MSI2,NRXN1,PCDH9,ATP13A4,GPM6A,RFX4,SOX5,SLC4A4,NKAIN3,MEIS2,CTNND2,SLC25A18,ZNRF3,CAMK2G,PTGDS,BMPR1B,ATP1A2,LRIG1,PARD3B,RYR3,SLC1A2,AHCYL2,ACSS1,NFIA,PITPNC1,LSAMP,PRODH,SORBS1,SPARCL1,SFXN5
6.110e-03	-5.10	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-follicular_lymphoma	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-follicular_lymphoma	981	8	16828	48	PCDH9,PARD3,NKAIN3,CTNND2,RORA,LSAMP,GPC5,SOX5
6.132e-03	-5.09	stomach-adenocarcinoma	COSMIC cancer mutations	stomach-adenocarcinoma	4101	20	16828	48	CTNND2,CDH20,GPC5,COL5A3,PCDH9,PAMR1,PARD3,ATP13A4,ATP1A2,LRIG1,RORA,PARD3B,FGFR3,SLC1A2,RFX4,AHCYL2,ACSS1,ABLIM1,SLC4A4,MEIS2
6.219e-03	-5.08	positive regulation of small molecule metabolic process	biological process	GO:0062013	142	3	18204	48	ZBTB20,SORBS1,SLC4A4
6.219e-03	-5.08	monoatomic anion transmembrane transport	biological process	GO:0098656	142	3	18204	48	SLC1A2,SLC4A4,SLC1A3
6.231e-03	-5.08	CATATPASE	prints domains	PR00119	35	2	5227	18	ATP1A2,ATP13A4
6.263e-03	-5.07	PAS domain	gene3d domains	3.30.450.20	40	2	14470	43	HIF3A,NPAS3
6.270e-03	-5.07	GSE1 (Gse1 coiled-coil protein)	protein interactions	23199	149	3	19454	49	TNIK,NFIA,SOX5
6.334e-03	-5.06	apical junction complex	cellular component	GO:0043296	150	3	19108	48	PARD3,PARD3B,SORBS1
6.490e-03	-5.04	follicular_lymphoma	COSMIC cancer mutations	follicular_lymphoma	1209	9	16828	48	GPC5,SOX5,CTNND2,RORA,TNIK,LSAMP,PARD3,NKAIN3,PCDH9
6.524e-03	-5.03	SFN (stratifin)	protein interactions	2810	671	6	19454	49	NFIA,ABLIM1,PARD3B,TNIK,PARD3,SORBS1
6.618e-03	-5.02	oligoastrocytoma_Grade_III	COSMIC cancer mutations	oligoastrocytoma_Grade_III	263	4	16828	48	FGFR3,RYR3,SOX5,SLC1A2
6.630e-03	-5.02	secondary active transmembrane transporter activity	molecular function	GO:0015291	289	4	18094	47	SLC1A3,SLC1A2,SLC25A18,SLC4A4
6.687e-03	-5.01	cell surface	cellular component	GO:0009986	896	7	19108	48	SLC1A2,ATP1A2,GPC5,NRXN1,FGFR3,SLC1A3,SLC4A4
6.702e-03	-5.01	kidney-carcinoma-clear_cell_renal_cell_carcinoma	COSMIC cancer mutations	kidney-carcinoma-clear_cell_renal_cell_carcinoma	13924	46	16828	48	ZNRF3,CTNND2,SLC25A18,CAMK2G,PTGDS,ATP1A2,LRIG1,BMPR1B,GPM6A,SOX5,NKAIN3,MEIS2,SLC4A4,PITPNC1,LSAMP,NFIA,PRODH,SORBS1,SPARCL1,SFXN5,RYR3,SLC1A2,PARD3B,ACSS1,AHCYL2,COL5A3,GPC5,FBXL7,PAMR1,NHSL1,PARD3,RORA,HIF3A,FGFR3,CDH20,GLIS3,ZBTB20,MSI2,NRXN1,PCDH9,ATP13A4,SLC1A3,TNIK,NPAS3,ABLIM1,DTNA
6.702e-03	-5.01	clear_cell_renal_cell_carcinoma	COSMIC cancer mutations	clear_cell_renal_cell_carcinoma	13924	46	16828	48	LRIG1,ATP1A2,BMPR1B,PARD3,PAMR1,PTGDS,NHSL1,CAMK2G,COL5A3,FBXL7,GPC5,ZNRF3,CTNND2,SLC25A18,NKAIN3,MEIS2,SLC4A4,SOX5,FGFR3,GPM6A,HIF3A,RORA,SPARCL1,SFXN5,ATP13A4,PRODH,NRXN1,SORBS1,PCDH9,ZBTB20,MSI2,LSAMP,CDH20,PITPNC1,GLIS3,NFIA,DTNA,ABLIM1,ACSS1,AHCYL2,RYR3,SLC1A2,NPAS3,PARD3B,SLC1A3,TNIK
6.715e-03	-5.00	adult behavior	biological process	GO:0030534	146	3	18204	48	SLC1A2,ATP1A2,NRXN1
6.856e-03	-4.98	trunk	COSMIC cancer mutations	trunk	3554	18	16828	48	NPAS3,FGFR3,SOX5,RYR3,HIF3A,SLC1A3,MEIS2,ABLIM1,CTNND2,GLIS3,CDH20,LSAMP,PARD3,ATP13A4,ATP1A2,SPARCL1,NRXN1,PCDH9
7.045e-03	-4.96	OSTEONECTIN_2	prosite domains	PS00613	2	1	12186	43	SPARCL1
7.045e-03	-4.96	OSTEONECTIN_1	prosite domains	PS00612	2	1	12186	43	SPARCL1
7.101e-03	-4.95	neuromuscular process	biological process	GO:0050905	149	3	18204	48	SLC1A3,NRXN1,CTNNA2
7.101e-03	-4.95	ATPASE_E1_E2	prosite domains	PS00154	36	2	12186	43	ATP1A2,ATP13A4
7.272e-03	-4.92	astrocytoma_Grade_I	COSMIC cancer mutations	astrocytoma_Grade_I	139	3	16828	48	GPC5,PARD3,FGFR3
7.322e-03	-4.92	cellular response to organic cyclic compound	biological process	GO:0071407	464	5	18204	48	ATP1A2,RYR3,SLC1A3,SLC1A2,RORA
7.349e-03	-4.91	DNA-binding transcription factor activity, RNA polymerase II-specific	molecular function	GO:0000981	1355	9	18094	47	RORA,SOX5,NFIA,GLIS3,RFX4,NPAS3,HIF3A,MEIS2,ZBTB20
7.399e-03	-4.91	visual learning	biological process	GO:0008542	49	2	18204	48	MEIS2,ATP1A2
7.538e-03	-4.89	Atg16l1 (autophagy related 16 like 1)	protein interactions	77040	3	1	19454	49	BMPR1B
7.538e-03	-4.89	Lrrc7 (leucine rich repeat containing 7)	protein interactions	117284	3	1	19454	49	CAMK2G
7.538e-03	-4.89	QRFPR (pyroglutamylated RFamide peptide receptor)	protein interactions	84109	3	1	19454	49	NTM
7.538e-03	-4.89	BCO1 (beta-carotene oxygenase 1)	protein interactions	53630	3	1	19454	49	ABLIM1
7.538e-03	-4.89	Usp45 (ubiquitin specific petidase 45)	protein interactions	77593	3	1	19454	49	BMPR1B
7.538e-03	-4.89	Rap2a (RAS related protein 2a)	protein interactions	76108	3	1	19454	49	BMPR1B
7.538e-03	-4.89	Chn1 (chimerin 1)	protein interactions	108699	3	1	19454	49	BMPR1B
7.538e-03	-4.89	Smad6 (SMAD family member 6)	protein interactions	17130	3	1	19454	49	BMPR1B
7.538e-03	-4.89	Hk2 (hexokinase 2)	protein interactions	25059	3	1	19454	49	PTGDS
7.538e-03	-4.89	Stk35 (serine/threonine kinase 35)	protein interactions	67333	3	1	19454	49	BMPR1B
7.538e-03	-4.89	PIGL (phosphatidylinositol glycan anchor biosynthesis class L)	protein interactions	9487	3	1	19454	49	MEIS2
7.538e-03	-4.89	TULP1 (TUB like protein 1)	protein interactions	7287	3	1	19454	49	NRXN1
7.538e-03	-4.89	Spop (speckle-type BTB/POZ protein)	protein interactions	20747	3	1	19454	49	GLIS3
7.538e-03	-4.89	Plekhb1 (pleckstrin homology domain containing, family B (evectins) member 1)	protein interactions	27276	3	1	19454	49	BMPR1B
7.538e-03	-4.89	Fbxw5 (F-box and WD-40 domain protein 5)	protein interactions	30839	3	1	19454	49	BMPR1B
7.544e-03	-4.89	AFDN (afadin, adherens junction formation factor)	protein interactions	4301	309	4	19454	49	DTNA,SORBS1,PARD3,NRXN1
7.689e-03	-4.87	carboxylic acid transport	biological process	GO:0046942	297	4	18204	48	SLC1A3,SLC1A2,SFXN5,SLC25A18
7.773e-03	-4.86	adenosylhomocysteinase activity	molecular function	GO:0004013	3	1	18094	47	AHCYL2
7.773e-03	-4.86	hydrolase activity, acting on carbon-sulfur bonds	molecular function	GO:0046508	3	1	18094	47	AHCYL2
7.773e-03	-4.86	cysteine transmembrane transporter activity	molecular function	GO:0033229	3	1	18094	47	SLC1A2
7.773e-03	-4.86	prostaglandin-D synthase activity	molecular function	GO:0004667	3	1	18094	47	PTGDS
7.774e-03	-4.86	learning	biological process	GO:0007612	154	3	18204	48	MEIS2,NRXN1,ATP1A2
7.779e-03	-4.86	organic acid transport	biological process	GO:0015849	298	4	18204	48	SLC1A3,SLC1A2,SFXN5,SLC25A18
7.890e-03	-4.84	acetate metabolic process	biological process	GO:0006083	3	1	18204	48	ACSS1
7.890e-03	-4.84	radial glia guided migration of Purkinje cell	biological process	GO:0021942	3	1	18204	48	CTNNA2
7.890e-03	-4.84	proline catabolic process to glutamate	biological process	GO:0010133	3	1	18204	48	PRODH
7.890e-03	-4.84	neuroligin clustering involved in postsynaptic membrane assembly	biological process	GO:0097118	3	1	18204	48	NRXN1
7.890e-03	-4.84	regulation of calcium:sodium antiporter activity	biological process	GO:1903279	3	1	18204	48	ATP1A2
7.890e-03	-4.84	cysteine transport	biological process	GO:0042883	3	1	18204	48	SLC1A2
7.890e-03	-4.84	cysteine transmembrane transport	biological process	GO:1903712	3	1	18204	48	SLC1A2
7.891e-03	-4.84	FOXF2 (forkhead box F2)	protein interactions	2295	53	2	19454	49	AHCYL2,ZBTB20
7.916e-03	-4.84	Vinculin_CS	interpro domains	IPR000633	3	1	18521	49	CTNNA2
7.916e-03	-4.84	HIF_alpha-like	interpro domains	IPR021537	3	1	18521	49	HIF3A
7.916e-03	-4.84	Myelin_PLP	interpro domains	IPR001614	3	1	18521	49	GPM6A
7.916e-03	-4.84	Adenosylhomocysteinase-like	interpro domains	IPR000043	3	1	18521	49	AHCYL2
7.916e-03	-4.84	SoHo_dom	interpro domains	IPR003127	3	1	18521	49	SORBS1
7.916e-03	-4.84	NR_DBD_ROR	interpro domains	IPR044101	3	1	18521	49	RORA
7.916e-03	-4.84	Ryanrecept_TM4-6	interpro domains	IPR009460	3	1	18521	49	RYR3
7.916e-03	-4.84	RYDR_Jsol	interpro domains	IPR048581	3	1	18521	49	RYR3
7.916e-03	-4.84	SPRY2_RyR	interpro domains	IPR035764	3	1	18521	49	RYR3
7.916e-03	-4.84	Ado_hCys_hydrolase_NAD-bd	interpro domains	IPR015878	3	1	18521	49	AHCYL2
7.916e-03	-4.84	FAD-linked_oxidoreductase-like	interpro domains	IPR029041	3	1	18521	49	PRODH
7.916e-03	-4.84	ROR_rcpt	interpro domains	IPR003079	3	1	18521	49	RORA
7.916e-03	-4.84	Myelin_PLP_CS	interpro domains	IPR018237	3	1	18521	49	GPM6A
7.916e-03	-4.84	Adenosylhomocyst_ase-like_sf	interpro domains	IPR042172	3	1	18521	49	AHCYL2
7.916e-03	-4.84	SPRY3_RyR	interpro domains	IPR035762	3	1	18521	49	RYR3
7.916e-03	-4.84	SPRY1_RyR	interpro domains	IPR035761	3	1	18521	49	RYR3
7.916e-03	-4.84	S-Ado-L-homoCys_hydrolase_CS	interpro domains	IPR020082	3	1	18521	49	AHCYL2
7.916e-03	-4.84	Ryan_recept	interpro domains	IPR013333	3	1	18521	49	RYR3
7.916e-03	-4.84	Ryanodine_rcpt	interpro domains	IPR003032	3	1	18521	49	RYR3
7.964e-03	-4.83	Cardiac conduction	REACTOME pathways	R-HSA-5576891	142	3	10285	30	RYR3,CAMK2G,ATP1A2
7.995e-03	-4.83	neuromuscular process controlling balance	biological process	GO:0050885	51	2	18204	48	SLC1A3,NRXN1
8.053e-03	-4.82	retina development in camera-type eye	biological process	GO:0060041	156	3	18204	48	BMPR1B,GPM6A,NFIA
8.111e-03	-4.81	CTNNB1 (catenin beta 1)	protein interactions	1499	926	7	19454	49	SORBS1,DTNA,PARD3B,NHSL1,CTNNA2,PARD3,CTNND2
8.238e-03	-4.80	RR_TM4-6	pfam domains	PF06459	3	1	17795	49	RYR3
8.238e-03	-4.80	Sorb	pfam domains	PF02208	3	1	17795	49	SORBS1
8.238e-03	-4.80	Myelin_PLP	pfam domains	PF01275	3	1	17795	49	GPM6A
8.238e-03	-4.80	RyR	pfam domains	PF02026	3	1	17795	49	RYR3
8.238e-03	-4.80	HIF-1	pfam domains	PF11413	3	1	17795	49	HIF3A
8.238e-03	-4.80	RYDR_Jsol	pfam domains	PF21119	3	1	17795	49	RYR3
8.238e-03	-4.80	AdoHcyase_NAD	pfam domains	PF00670	3	1	17795	49	AHCYL2
8.238e-03	-4.80	AdoHcyase	pfam domains	PF05221	3	1	17795	49	AHCYL2
8.266e-03	-4.80	central_nervous_system-temporoparietal-glioma-astrocytoma_Grade_IV	COSMIC cancer mutations	central_nervous_system-temporoparietal-glioma-astrocytoma_Grade_IV	48	2	16828	48	RYR3,PARD3
8.301e-03	-4.79	regulation of purine nucleotide catabolic process	biological process	GO:0033121	52	2	18204	48	ZBTB20,SLC4A4
8.301e-03	-4.79	regulation of nucleotide catabolic process	biological process	GO:0030811	52	2	18204	48	ZBTB20,SLC4A4
8.301e-03	-4.79	regulation of glycolytic process	biological process	GO:0006110	52	2	18204	48	ZBTB20,SLC4A4
8.316e-03	-4.79	acute_myeloid_leukaemia	COSMIC cancer mutations	acute_myeloid_leukaemia	10418	38	16828	48	PRODH,PCDH9,NRXN1,SPARCL1,ATP13A4,SFXN5,NFIA,CDH20,LSAMP,GLIS3,MSI2,AHCYL2,ABLIM1,ACSS1,SLC1A3,TNIK,PARD3B,NPAS3,RYR3,SLC1A2,NHSL1,PAMR1,PARD3,ATP1A2,LRIG1,CTNND2,COL5A3,FBXL7,GPC5,CAMK2G,SLC4A4,NKAIN3,MEIS2,HIF3A,RORA,NTM,SOX5,RFX4
8.316e-03	-4.79	haematopoietic_and_lymphoid_tissue-haematopoietic_neoplasm-acute_myeloid_leukaemia	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue-haematopoietic_neoplasm-acute_myeloid_leukaemia	10418	38	16828	48	RORA,HIF3A,NTM,SOX5,RFX4,SLC4A4,NKAIN3,MEIS2,CTNND2,COL5A3,FBXL7,GPC5,CAMK2G,NHSL1,PAMR1,PARD3,ATP1A2,LRIG1,SLC1A3,TNIK,NPAS3,PARD3B,RYR3,SLC1A2,AHCYL2,ABLIM1,ACSS1,NFIA,CDH20,LSAMP,GLIS3,MSI2,PRODH,PCDH9,NRXN1,SPARCL1,ATP13A4,SFXN5
8.365e-03	-4.78	ATPase-coupled monoatomic cation transmembrane transporter activity	molecular function	GO:0019829	53	2	18094	47	ATP13A4,ATP1A2
8.444e-03	-4.77	RNA polymerase II transcription regulatory region sequence-specific DNA binding	molecular function	GO:0000977	1385	9	18094	47	HIF3A,RFX4,NPAS3,ZBTB20,MEIS2,SOX5,RORA,GLIS3,NFIA
8.447e-03	-4.77	ion binding	molecular function	GO:0043167	6007	24	18094	47	PCDH9,PITPNC1,SLC1A2,ACSS1,ATP13A4,CAMK2G,SPARCL1,RORA,DTNA,SLC1A3,PRODH,NRXN1,PAMR1,ATP1A2,ABLIM1,RYR3,ZBTB20,PTGDS,PARD3,GLIS3,FGFR3,BMPR1B,ZNRF3,TNIK
8.477e-03	-4.77	SYN1 (synapsin I)	protein interactions	6853	55	2	19454	49	CAMK2G,GPM6A
8.483e-03	-4.77	monoatomic anion transport	biological process	GO:0006820	159	3	18204	48	SLC1A2,SLC4A4,SLC1A3
8.500e-03	-4.77	Hippo signaling pathway	KEGG pathways	ko04390	154	3	7161	20	BMPR1B,PARD3,CTNNA2
8.500e-03	-4.77	Hippo signaling pathway	KEGG pathways	hsa04390	154	3	7161	20	CTNNA2,BMPR1B,PARD3
8.533e-03	-4.76	skin-face-lentigo	COSMIC cancer mutations	skin-face-lentigo	3	1	16828	48	FGFR3
8.533e-03	-4.76	skin-leg-other-seborrhoeic_keratosis	COSMIC cancer mutations	skin-leg-other-seborrhoeic_keratosis	3	1	16828	48	FGFR3
8.533e-03	-4.76	skin-lentigo	COSMIC cancer mutations	skin-lentigo	3	1	16828	48	FGFR3
8.533e-03	-4.76	skin-forearm-lentigo	COSMIC cancer mutations	skin-forearm-lentigo	3	1	16828	48	FGFR3
8.533e-03	-4.76	lentigo	COSMIC cancer mutations	lentigo	3	1	16828	48	FGFR3
8.533e-03	-4.76	skin-trunk-lentigo	COSMIC cancer mutations	skin-trunk-lentigo	3	1	16828	48	FGFR3
8.533e-03	-4.76	skin-trunk-other-seborrhoeic_keratosis	COSMIC cancer mutations	skin-trunk-other-seborrhoeic_keratosis	3	1	16828	48	FGFR3
8.533e-03	-4.76	skin-hand-lentigo	COSMIC cancer mutations	skin-hand-lentigo	3	1	16828	48	FGFR3
8.533e-03	-4.76	skin-leg-lentigo	COSMIC cancer mutations	skin-leg-lentigo	3	1	16828	48	FGFR3
8.533e-03	-4.76	urinary_tract-bladder-papilloma	COSMIC cancer mutations	urinary_tract-bladder-papilloma	3	1	16828	48	FGFR3
8.571e-03	-4.76	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-plasma_cell_myeloma	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-plasma_cell_myeloma	1263	9	16828	48	RYR3,FGFR3,TNIK,GPM6A,NTM,CTNND2,ATP13A4,ABLIM1,PAMR1
8.571e-03	-4.76	plasma_cell_myeloma	COSMIC cancer mutations	plasma_cell_myeloma	1263	9	16828	48	PAMR1,ABLIM1,ATP13A4,NTM,CTNND2,GPM6A,TNIK,FGFR3,RYR3
8.612e-03	-4.75	regulation of chondrocyte differentiation	biological process	GO:0032330	53	2	18204	48	BMPR1B,SOX5
8.612e-03	-4.75	neutral amino acid transport	biological process	GO:0015804	53	2	18204	48	SLC1A2,SLC1A3
8.642e-03	-4.75	presynaptic membrane	cellular component	GO:0042734	168	3	19108	48	NRXN1,SLC1A2,GPM6A
8.685e-03	-4.75	LYN (LYN proto-oncogene, Src family tyrosine kinase)	protein interactions	4067	713	6	19454	49	DTNA,SLC1A3,ABLIM1,PARD3,TNIK,MSI2
8.776e-03	-4.74	export from cell	biological process	GO:0140352	485	5	18204	48	ATP1A2,NRXN1,SLC4A4,CAMK2G,PTGDS
8.889e-03	-4.72	-	gene3d domains	3.20.20.220	3	1	14470	43	PRODH
8.889e-03	-4.72	-	gene3d domains	1.10.490.160	3	1	14470	43	RYR3
8.889e-03	-4.72	-	gene3d domains	6.10.250.2510	3	1	14470	43	CTNNA2
8.889e-03	-4.72	Adenosylhomocysteinase-like	gene3d domains	3.40.50.1480	3	1	14470	43	AHCYL2
9.081e-03	-4.70	NXPH3 (neurexophilin 3)	protein interactions	11248	57	2	19454	49	CTNNA2,NRXN1
9.109e-03	-4.70	response to light stimulus	biological process	GO:0009416	312	4	18204	48	ATP1A2,SLC1A3,MEIS2,SLC1A2
9.129e-03	-4.70	cellular homeostasis	biological process	GO:0019725	689	6	18204	48	SLC1A3,SLC4A4,ATP13A4,ZBTB20,RYR3,ATP1A2
9.165e-03	-4.69	ROR2 (receptor tyrosine kinase like orphan receptor 2)	protein interactions	4920	327	4	19454	49	PARD3,SORBS1,DTNA,TNIK
9.249e-03	-4.68	response to cocaine	biological process	GO:0042220	55	2	18204	48	SLC1A3,SLC1A2
9.249e-03	-4.68	establishment or maintenance of epithelial cell apical/basal polarity	biological process	GO:0045197	55	2	18204	48	PARD3,PARD3B
9.253e-03	-4.68	mucosal	COSMIC cancer mutations	mucosal	2009	12	16828	48	RORA,FGFR3,ABLIM1,CTNND2,COL5A3,SORBS1,PCDH9,ATP1A2,SPARCL1,ATP13A4,PARD3,BMPR1B
9.253e-03	-4.68	skin-mucosal-malignant_melanoma	COSMIC cancer mutations	skin-mucosal-malignant_melanoma	2009	12	16828	48	COL5A3,CTNND2,PARD3,BMPR1B,ATP13A4,SPARCL1,ATP1A2,PCDH9,SORBS1,FGFR3,RORA,ABLIM1
9.383e-03	-4.67	import across plasma membrane	biological process	GO:0098739	165	3	18204	48	ATP1A2,SLC1A3,SLC1A2
9.390e-03	-4.67	CILK1 (ciliogenesis associated kinase 1)	protein interactions	22858	58	2	19454	49	CAMK2G,MSI2
9.391e-03	-4.67	urinary_tract-bladder-carcinoma	COSMIC cancer mutations	urinary_tract-bladder-carcinoma	14050	46	16828	48	DTNA,ABLIM1,NPAS3,SLC1A3,TNIK,ATP13A4,NRXN1,PCDH9,ZBTB20,MSI2,CDH20,GLIS3,FGFR3,HIF3A,RORA,NTM,PARD3,PAMR1,COL5A3,GPC5,FBXL7,ACSS1,AHCYL2,RYR3,SLC1A2,PARD3B,SPARCL1,SFXN5,PRODH,SORBS1,PITPNC1,LSAMP,NFIA,MEIS2,SLC4A4,RFX4,SOX5,GPM6A,ATP1A2,LRIG1,BMPR1B,PTGDS,CAMK2G,ZNRF3,CTNND2,SLC25A18
9.578e-03	-4.65	chemical homeostasis	biological process	GO:0048878	914	7	18204	48	SLC1A3,ZBTB20,RYR3,ATP13A4,ATP1A2,SLC4A4,RORA
9.597e-03	-4.65	Neurotransmitter Release Cycle	REACTOME pathways	R-HSA-112310	51	2	10285	30	SLC1A2,SLC1A3
9.657e-03	-4.64	extrinsic component of membrane	cellular component	GO:0019898	175	3	19108	48	DTNA,CDH20,CTNNA2
9.687e-03	-4.64	ACTB (actin beta)	protein interactions	60	958	7	19454	49	NHSL1,ABLIM1,DTNA,SORBS1,AHCYL2,SFXN5,MEIS2
9.733e-03	-4.63	gallbladder	COSMIC cancer mutations	gallbladder	2821	15	16828	48	COL5A3,CTNND2,ZNRF3,PITPNC1,PARD3,SPARCL1,LRIG1,NHSL1,PCDH9,PRODH,FGFR3,RYR3,TNIK,SLC4A4,NKAIN3
9.733e-03	-4.63	biliary_tract-gallbladder-carcinoma-adenocarcinoma	COSMIC cancer mutations	biliary_tract-gallbladder-carcinoma-adenocarcinoma	2821	15	16828	48	NKAIN3,SLC4A4,TNIK,RYR3,FGFR3,PCDH9,PRODH,NHSL1,SPARCL1,LRIG1,PARD3,ZNRF3,PITPNC1,CTNND2,COL5A3
9.834e-03	-4.62	skin-trunk-malignant_melanoma-nodular	COSMIC cancer mutations	skin-trunk-malignant_melanoma-nodular	1291	9	16828	48	ATP13A4,SPARCL1,ATP1A2,ABLIM1,NPAS3,GLIS3,CDH20,HIF3A,CTNND2
9.873e-03	-4.62	skin-upper_leg-malignant_melanoma	COSMIC cancer mutations	skin-upper_leg-malignant_melanoma	850	7	16828	48	LRIG1,PAMR1,PCDH9,ACSS1,NFIA,HIF3A,GLIS3
1.001e-02	-4.60	internode region of axon	cellular component	GO:0033269	4	1	19108	48	PARD3
1.001e-02	-4.60	collagen type V trimer	cellular component	GO:0005588	4	1	19108	48	COL5A3
1.002e-02	-4.60	SNTB1 (syntrophin beta 1)	protein interactions	6641	60	2	19454	49	DTNA,FGFR3
1.004e-02	-4.60	CCDC126 (coiled-coil domain containing 126)	protein interactions	90693	4	1	19454	49	GPM6A
1.004e-02	-4.60	Srgap1 (SLIT-ROBO Rho GTPase activating protein 1)	protein interactions	117600	4	1	19454	49	BMPR1B
1.004e-02	-4.60	Cdk14 (cyclin dependent kinase 14)	protein interactions	18647	4	1	19454	49	BMPR1B
1.004e-02	-4.60	CALML4 (calmodulin like 4)	protein interactions	91860	4	1	19454	49	CAMK2G
1.004e-02	-4.60	Nkiras1 (NFKB inhibitor interacting Ras-like protein 1)	protein interactions	69721	4	1	19454	49	BMPR1B
1.004e-02	-4.60	Ilkap (integrin-linked kinase-associated serine/threonine phosphatase 2C)	protein interactions	67444	4	1	19454	49	BMPR1B
1.004e-02	-4.60	Rhebl1 (Ras homolog enriched in brain like 1)	protein interactions	69159	4	1	19454	49	BMPR1B
1.004e-02	-4.60	Dnaja1 (DnaJ heat shock protein family (Hsp40) member A1)	protein interactions	15502	4	1	19454	49	GLIS3
1.004e-02	-4.60	Arhgef6 (Rac/Cdc42 guanine nucleotide exchange factor 6)	protein interactions	73341	4	1	19454	49	BMPR1B
1.004e-02	-4.60	Naa20 (N(alpha)-acetyltransferase 20, NatB catalytic subunit)	protein interactions	67877	4	1	19454	49	BMPR1B
1.004e-02	-4.60	Nme2 (NME/NM23 nucleoside diphosphate kinase 2)	protein interactions	18103	4	1	19454	49	RORA
1.004e-02	-4.60	SYNPO (synaptopodin)	protein interactions	11346	177	3	19454	49	ABLIM1,CAMK2G,ZBTB20
1.015e-02	-4.59	synapse	cellular component	GO:0045202	1473	9	19108	48	CTNND2,TNIK,GPM6A,SLC1A3,DTNA,SLC1A2,ATP1A2,NRXN1,SPARCL1
1.016e-02	-4.59	EZR (ezrin)	protein interactions	7430	526	5	19454	49	AHCYL2,SORBS1,DTNA,TNIK,ABLIM1
1.027e-02	-4.58	IGc2	smart domains	SM00408	239	4	9717	35	LRIG1,NTM,LSAMP,FGFR3
1.030e-02	-4.58	RYANODINER	prints domains	PR00795	3	1	5227	18	RYR3
1.030e-02	-4.58	MYELINPLP	prints domains	PR00214	3	1	5227	18	GPM6A
1.030e-02	-4.58	RORNUCRECPTR	prints domains	PR01293	3	1	5227	18	RORA
1.030e-02	-4.58	PGNDSYNTHASE	prints domains	PR01254	3	1	5227	18	PTGDS
1.033e-02	-4.57	RNA polymerase II cis-regulatory region sequence-specific DNA binding	molecular function	GO:0000978	1180	8	18094	47	NFIA,GLIS3,RORA,SOX5,MEIS2,ZBTB20,RFX4,HIF3A
1.034e-02	-4.57	monoatomic cation homeostasis	biological process	GO:0055080	505	5	18204	48	ATP1A2,ATP13A4,SLC1A3,RYR3,SLC4A4
1.034e-02	-4.57	Synaptic Vesicle Pathway	WikiPathways	WP2267	52	2	5310	16	SLC1A3,ATP1A2
1.035e-02	-4.57	propionate-CoA ligase activity	molecular function	GO:0050218	4	1	18094	47	ACSS1
1.035e-02	-4.57	short-chain fatty acid-CoA ligase activity	molecular function	GO:0031955	4	1	18094	47	ACSS1
1.035e-02	-4.57	oxidoreductase activity, acting on the CH-NH group of donors, quinone or similar compound as acceptor	molecular function	GO:0016649	4	1	18094	47	PRODH
1.035e-02	-4.57	acetate-CoA ligase activity	molecular function	GO:0003987	4	1	18094	47	ACSS1
1.035e-02	-4.57	ryanodine-sensitive calcium-release channel activity	molecular function	GO:0005219	4	1	18094	47	RYR3
1.035e-02	-4.57	tricarboxylic acid transmembrane transporter activity	molecular function	GO:0015142	4	1	18094	47	SFXN5
1.035e-02	-4.57	citrate transmembrane transporter activity	molecular function	GO:0015137	4	1	18094	47	SFXN5
1.043e-02	-4.56	binding	molecular function	GO:0005488	16422	47	18094	47	ABLIM1,RYR3,ZBTB20,PTGDS,CTNNA2,GPC5,COL5A3,ZNRF3,CDH20,TNIK,LRIG1,PARD3,SFXN5,SOX5,MEIS2,ACSS1,ATP13A4,HIF3A,PCDH9,GPM6A,AHCYL2,FBXL7,CTNND2,SORBS1,SLC1A3,ATP1A2,PARD3B,RFX4,NRXN1,SLC4A4,PAMR1,GLIS3,FGFR3,NTM,BMPR1B,SLC25A18,MSI2,LSAMP,CAMK2G,NFIA,PITPNC1,SLC1A2,PRODH,NPAS3,SPARCL1,DTNA,RORA
1.051e-02	-4.56	4-hydroxyproline catabolic process	biological process	GO:0019470	4	1	18204	48	PRODH
1.051e-02	-4.56	positive regulation of cardiac muscle myoblast proliferation	biological process	GO:0110024	4	1	18204	48	MEIS2
1.051e-02	-4.56	response to glycoside	biological process	GO:1903416	4	1	18204	48	ATP1A2
1.051e-02	-4.56	short-chain fatty acid biosynthetic process	biological process	GO:0051790	4	1	18204	48	ACSS1
1.051e-02	-4.56	regulation of amino acid uptake involved in synaptic transmission	biological process	GO:0051941	4	1	18204	48	ATP1A2
1.051e-02	-4.56	malate-aspartate shuttle	biological process	GO:0043490	4	1	18204	48	SLC25A18
1.051e-02	-4.56	proline catabolic process	biological process	GO:0006562	4	1	18204	48	PRODH
1.051e-02	-4.56	ovarian cumulus expansion	biological process	GO:0001550	4	1	18204	48	BMPR1B
1.051e-02	-4.56	negative regulation of male germ cell proliferation	biological process	GO:2000255	4	1	18204	48	PTGDS
1.051e-02	-4.56	positive regulation of mesenchymal stem cell differentiation	biological process	GO:2000741	4	1	18204	48	SOX5
1.051e-02	-4.56	negative regulation of germ cell proliferation	biological process	GO:1905937	4	1	18204	48	PTGDS
1.051e-02	-4.56	regulation of glutamate uptake involved in transmission of nerve impulse	biological process	GO:0051946	4	1	18204	48	ATP1A2
1.054e-02	-4.55	CTF/NFI_DNA-bd-dom	interpro domains	IPR020604	4	1	18521	49	NFIA
1.054e-02	-4.55	CTF/NFI_DNA-bd_CS	interpro domains	IPR019739	4	1	18521	49	NFIA
1.054e-02	-4.55	AbLIM_anchor	interpro domains	IPR032402	4	1	18521	49	ABLIM1
1.054e-02	-4.55	Ca/CaM-dep_prot_kinase-assoc	interpro domains	IPR013543	4	1	18521	49	CAMK2G
1.054e-02	-4.55	CTF/NFI_DNA-bd_N	interpro domains	IPR019548	4	1	18521	49	NFIA
1.054e-02	-4.55	FGF_rcpt_fam	interpro domains	IPR016248	4	1	18521	49	FGFR3
1.054e-02	-4.55	Alpha_catenin	interpro domains	IPR001033	4	1	18521	49	CTNNA2
1.054e-02	-4.55	P5A-ATPase_N	interpro domains	IPR047819	4	1	18521	49	ATP13A4
1.054e-02	-4.55	Na/K-Atpase_Interacting	interpro domains	IPR008516	4	1	18521	49	NKAIN3
1.054e-02	-4.55	CTF/NFI	interpro domains	IPR000647	4	1	18521	49	NFIA
1.054e-02	-4.55	PKNOX/Meis_N	interpro domains	IPR032453	4	1	18521	49	MEIS2
1.054e-02	-4.55	ACAS_N	interpro domains	IPR032387	4	1	18521	49	ACSS1
1.054e-02	-4.55	P5B-type_ATPase	interpro domains	IPR047821	4	1	18521	49	ATP13A4
1.054e-02	-4.55	NHS-like	interpro domains	IPR024845	4	1	18521	49	NHSL1
1.055e-02	-4.55	MYELIN_PLP_1	prosite domains	PS00575	3	1	12186	43	GPM6A
1.055e-02	-4.55	VINCULIN_1	prosite domains	PS00663	3	1	12186	43	CTNNA2
1.055e-02	-4.55	ADOHCYASE_1	prosite domains	PS00738	3	1	12186	43	AHCYL2
1.055e-02	-4.55	MYELIN_PLP_2	prosite domains	PS01004	3	1	12186	43	GPM6A
1.055e-02	-4.55	ADOHCYASE_2	prosite domains	PS00739	3	1	12186	43	AHCYL2
1.055e-02	-4.55	SOHO	prosite domains	PS50831	3	1	12186	43	SORBS1
1.059e-02	-4.55	endochondral bone morphogenesis	biological process	GO:0060350	59	2	18204	48	BMPR1B,FGFR3
1.059e-02	-4.55	establishment or maintenance of apical/basal cell polarity	biological process	GO:0035088	59	2	18204	48	PARD3B,PARD3
1.059e-02	-4.55	establishment or maintenance of bipolar cell polarity	biological process	GO:0061245	59	2	18204	48	PARD3B,PARD3
1.059e-02	-4.55	biliary_tract	COSMIC cancer mutations	biliary_tract	15309	48	16828	48	LRIG1,ATP1A2,BMPR1B,PTGDS,CAMK2G,ZNRF3,SLC25A18,CTNND2,MEIS2,NKAIN3,SLC4A4,RFX4,SOX5,GPM6A,SFXN5,SPARCL1,SORBS1,PRODH,PITPNC1,LSAMP,NFIA,ACSS1,AHCYL2,SLC1A2,RYR3,PARD3B,PARD3,PAMR1,NHSL1,FBXL7,GPC5,COL5A3,FGFR3,NTM,RORA,HIF3A,ATP13A4,NRXN1,PCDH9,MSI2,ZBTB20,GLIS3,CDH20,DTNA,ABLIM1,NPAS3,TNIK,SLC1A3
1.067e-02	-4.54	ARHGAP29 (Rho GTPase activating protein 29)	protein interactions	9411	62	2	19454	49	CAMK2G,PARD3
1.077e-02	-4.53	AdoHcyase_NAD	smart domains	SM00997	3	1	9717	35	AHCYL2
1.077e-02	-4.53	AdoHcyase	smart domains	SM00996	3	1	9717	35	AHCYL2
1.077e-02	-4.53	PLP	smart domains	SM00002	3	1	9717	35	GPM6A
1.077e-02	-4.53	Sorb	smart domains	SM00459	3	1	9717	35	SORBS1
1.082e-02	-4.53	DNA-binding transcription factor activity	molecular function	GO:0003700	1441	9	18094	47	RFX4,NPAS3,HIF3A,MEIS2,ZBTB20,RORA,SOX5,NFIA,GLIS3
1.084e-02	-4.52	inorganic ion transmembrane transport	biological process	GO:0098660	715	6	18204	48	SLC4A4,ATP1A2,RYR3,SLC25A18,SLC1A3,GPM6A
1.093e-02	-4.52	export across plasma membrane	biological process	GO:0140115	60	2	18204	48	ATP1A2,SLC4A4
1.093e-02	-4.52	regulation of glucose import	biological process	GO:0046324	60	2	18204	48	SORBS1,SLC1A2
1.097e-02	-4.51	NfI_DNAbd_pre-N	pfam domains	PF10524	4	1	17795	49	NFIA
1.097e-02	-4.51	P5-ATPase	pfam domains	PF12409	4	1	17795	49	ATP13A4
1.097e-02	-4.51	AbLIM_anchor	pfam domains	PF16182	4	1	17795	49	ABLIM1
1.097e-02	-4.51	NKAIN	pfam domains	PF05640	4	1	17795	49	NKAIN3
1.097e-02	-4.51	CTF_NFI	pfam domains	PF00859	4	1	17795	49	NFIA
1.097e-02	-4.51	Meis_PKNOX_N	pfam domains	PF16493	4	1	17795	49	MEIS2
1.097e-02	-4.51	CaMKII_AD	pfam domains	PF08332	4	1	17795	49	CAMK2G
1.097e-02	-4.51	NHS	pfam domains	PF15273	4	1	17795	49	NHSL1
1.097e-02	-4.51	ACAS_N	pfam domains	PF16177	4	1	17795	49	ACSS1
1.106e-02	-4.50	bladder	COSMIC cancer mutations	bladder	14112	46	16828	48	SLC1A3,TNIK,NPAS3,ABLIM1,DTNA,CDH20,GLIS3,ZBTB20,MSI2,PCDH9,NRXN1,ATP13A4,HIF3A,RORA,NTM,FGFR3,COL5A3,FBXL7,GPC5,PAMR1,PARD3,RYR3,SLC1A2,PARD3B,ACSS1,AHCYL2,PITPNC1,LSAMP,NFIA,PRODH,SORBS1,SPARCL1,SFXN5,GPM6A,SOX5,RFX4,MEIS2,SLC4A4,ZNRF3,CTNND2,SLC25A18,CAMK2G,PTGDS,LRIG1,ATP1A2,BMPR1B
1.106e-02	-4.50	urinary_tract	COSMIC cancer mutations	urinary_tract	14112	46	16828	48	NRXN1,PCDH9,ATP13A4,GLIS3,CDH20,MSI2,ZBTB20,ABLIM1,DTNA,TNIK,SLC1A3,NPAS3,PAMR1,PARD3,FBXL7,GPC5,COL5A3,NTM,HIF3A,RORA,FGFR3,SORBS1,PRODH,SFXN5,SPARCL1,NFIA,PITPNC1,LSAMP,AHCYL2,ACSS1,PARD3B,SLC1A2,RYR3,PTGDS,BMPR1B,LRIG1,ATP1A2,SLC25A18,CTNND2,ZNRF3,CAMK2G,SLC4A4,MEIS2,GPM6A,SOX5,RFX4
1.106e-02	-4.50	L-citrulline biosynthesis	BIOCYC pathways	META_CITRULBIO-PWY	5	1	902	2	PRODH
1.114e-02	-4.50	regulation of small molecule metabolic process	biological process	GO:0062012	331	4	18204	48	SLC4A4,SORBS1,RORA,ZBTB20
1.119e-02	-4.49	monoatomic ion homeostasis	biological process	GO:0050801	515	5	18204	48	SLC4A4,RYR3,SLC1A3,ATP13A4,ATP1A2
1.120e-02	-4.49	human chr14q13.1	chromosome location	human chr14q13.1	6	1	26134	49	NPAS3
1.120e-02	-4.49	human chr4q34.2	chromosome location	human chr4q34.2	6	1	26134	49	GPM6A
1.134e-02	-4.48	EVA1C (eva-1 homolog C)	protein interactions	59271	64	2	19454	49	BMPR1B,PCDH9
1.136e-02	-4.48	urinary_tract-bladder-other-normal	COSMIC cancer mutations	urinary_tract-bladder-other-normal	4	1	16828	48	FGFR3
1.136e-02	-4.48	inverted	COSMIC cancer mutations	inverted	4	1	16828	48	FGFR3
1.136e-02	-4.48	skin-benign_melanocytic_nevus-junctional	COSMIC cancer mutations	skin-benign_melanocytic_nevus-junctional	4	1	16828	48	FGFR3
1.136e-02	-4.48	urinary_tract-bladder-papilloma-inverted	COSMIC cancer mutations	urinary_tract-bladder-papilloma-inverted	4	1	16828	48	FGFR3
1.146e-02	-4.47	CDH1 (cadherin 1)	protein interactions	999	757	6	19454	49	PARD3,SORBS1,CTNND2,CTNNA2,NHSL1,ABLIM1
1.148e-02	-4.47	adenoma	COSMIC cancer mutations	adenoma	2873	15	16828	48	PCDH9,BMPR1B,PARD3,CDH20,CTNND2,ZBTB20,COL5A3,GPC5,ACSS1,GPM6A,HIF3A,RYR3,SOX5,FGFR3,NPAS3
1.152e-02	-4.46	cis-regulatory region sequence-specific DNA binding	molecular function	GO:0000987	1203	8	18094	47	SOX5,RORA,GLIS3,NFIA,HIF3A,RFX4,ZBTB20,MEIS2
1.164e-02	-4.45	regulation of carbohydrate catabolic process	biological process	GO:0043470	62	2	18204	48	SLC4A4,ZBTB20
1.188e-02	-4.43	arm	COSMIC cancer mutations	arm	1331	9	16828	48	ATP1A2,SLC4A4,SORBS1,NPAS3,FGFR3,PARD3B,ZBTB20,COL5A3,NTM
1.204e-02	-4.42	central_nervous_system-brain-primitive_neuroectodermal_tumour-medulloblastoma-medullomyoblastoma	COSMIC cancer mutations	central_nervous_system-brain-primitive_neuroectodermal_tumour-medulloblastoma-medullomyoblastoma	485	5	16828	48	SLC4A4,RYR3,ATP13A4,LSAMP,PCDH9
1.204e-02	-4.42	medullomyoblastoma	COSMIC cancer mutations	medullomyoblastoma	485	5	16828	48	SLC4A4,RYR3,ATP13A4,LSAMP,PCDH9
1.205e-02	-4.42	primitive_neuroectodermal_tumour-medulloblastoma	COSMIC cancer mutations	primitive_neuroectodermal_tumour-medulloblastoma	15350	48	16828	48	ACSS1,AHCYL2,RYR3,SLC1A2,PARD3B,PRODH,SORBS1,SPARCL1,SFXN5,PITPNC1,LSAMP,NFIA,NKAIN3,MEIS2,SLC4A4,GPM6A,RFX4,SOX5,PTGDS,ATP1A2,LRIG1,BMPR1B,ZNRF3,CTNND2,SLC25A18,CAMK2G,ABLIM1,DTNA,SLC1A3,TNIK,NPAS3,NRXN1,PCDH9,ATP13A4,CDH20,GLIS3,ZBTB20,MSI2,RORA,HIF3A,NTM,FGFR3,PAMR1,NHSL1,PARD3,COL5A3,FBXL7,GPC5
1.208e-02	-4.42	response to growth factor	biological process	GO:0070848	525	5	18204	48	BMPR1B,MEIS2,FGFR3,SOX5,NFIA
1.237e-02	-4.39	dendrite morphogenesis	biological process	GO:0048813	64	2	18204	48	CTNNA2,CTNND2
1.247e-02	-4.38	head_neck	COSMIC cancer mutations	head_neck	15361	48	16828	48	SORBS1,PRODH,SFXN5,SPARCL1,LSAMP,PITPNC1,NFIA,ACSS1,AHCYL2,SLC1A2,RYR3,PARD3B,PTGDS,ATP1A2,LRIG1,BMPR1B,ZNRF3,SLC25A18,CTNND2,CAMK2G,MEIS2,NKAIN3,SLC4A4,GPM6A,SOX5,RFX4,PCDH9,NRXN1,ATP13A4,GLIS3,CDH20,MSI2,ZBTB20,ABLIM1,DTNA,TNIK,SLC1A3,NPAS3,PAMR1,NHSL1,PARD3,FBXL7,GPC5,COL5A3,NTM,HIF3A,RORA,FGFR3
1.250e-02	-4.38	calcium- and calmodulin-dependent protein kinase complex	cellular component	GO:0005954	5	1	19108	48	CAMK2G
1.252e-02	-4.38	membrane protein complex	cellular component	GO:0098796	1261	8	19108	48	SLC1A3,BMPR1B,SORBS1,RYR3,CDH20,ATP1A2,SLC1A2,CTNNA2
1.253e-02	-4.38	Rhobtb1 (Rho-related BTB domain containing 1)	protein interactions	69288	5	1	19454	49	BMPR1B
1.253e-02	-4.38	SYT13 (synaptotagmin 13)	protein interactions	57586	5	1	19454	49	NRXN1
1.253e-02	-4.38	RFX4 (regulatory factor X4)	protein interactions	5992	5	1	19454	49	RFX4
1.253e-02	-4.38	Rras2 (related RAS viral (r-ras) oncogene 2)	protein interactions	66922	5	1	19454	49	BMPR1B
1.253e-02	-4.38	ARSI (arylsulfatase family member I)	protein interactions	340075	5	1	19454	49	AHCYL2
1.253e-02	-4.38	Rab6b (RAB6B, member RAS oncogene family)	protein interactions	270192	5	1	19454	49	BMPR1B
1.253e-02	-4.38	Wwp2 (WW domain containing E3 ubiquitin protein ligase 2)	protein interactions	66894	5	1	19454	49	GLIS3
1.253e-02	-4.38	Hk3 (hexokinase 3)	protein interactions	25060	5	1	19454	49	PTGDS
1.253e-02	-4.38	CAMK2N2 (calcium/calmodulin dependent protein kinase II inhibitor 2)	protein interactions	94032	5	1	19454	49	CAMK2G
1.253e-02	-4.38	Rab38 (RAB38, member RAS oncogene family)	protein interactions	72433	5	1	19454	49	BMPR1B
1.253e-02	-4.38	Cdk4 (cyclin dependent kinase 4)	protein interactions	12567	5	1	19454	49	BMPR1B
1.253e-02	-4.38	Rhoj (ras homolog family member J)	protein interactions	80837	5	1	19454	49	BMPR1B
1.253e-02	-4.38	SLC10A3 (solute carrier family 10 member 3)	protein interactions	8273	5	1	19454	49	SORBS1
1.253e-02	-4.38	PTGER2 (prostaglandin E receptor 2)	protein interactions	5732	5	1	19454	49	PTGDS
1.258e-02	-4.38	bone-extraskeletal-Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour	COSMIC cancer mutations	bone-extraskeletal-Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour	891	7	16828	48	PTGDS,ABLIM1,SPARCL1,ATP1A2,LRIG1,NPAS3,FGFR3
1.267e-02	-4.37	main axon	cellular component	GO:0044304	68	2	19108	48	PARD3,SLC1A2
1.283e-02	-4.36	small molecule binding	molecular function	GO:0036094	6197	24	18094	47	ZBTB20,RYR3,ABLIM1,ATP1A2,PTGDS,NRXN1,PAMR1,TNIK,ZNRF3,GLIS3,PARD3,BMPR1B,FGFR3,ACSS1,CAMK2G,ATP13A4,PITPNC1,PCDH9,SLC1A2,PRODH,SLC1A3,RORA,DTNA,SPARCL1
1.292e-02	-4.35	fibroblast growth factor receptor activity	molecular function	GO:0005007	5	1	18094	47	FGFR3
1.292e-02	-4.35	neuroligin family protein binding	molecular function	GO:0097109	5	1	18094	47	NRXN1
1.292e-02	-4.35	transforming growth factor beta receptor activity, type I	molecular function	GO:0005025	5	1	18094	47	BMPR1B
1.295e-02	-4.35	human chr22q11.21	chromosome location	human chr22q11.21	92	2	26134	49	PRODH,SLC25A18
1.302e-02	-4.34	transcription cis-regulatory region binding	molecular function	GO:0000976	1485	9	18094	47	RORA,SOX5,NFIA,GLIS3,NPAS3,RFX4,HIF3A,MEIS2,ZBTB20
1.305e-02	-4.34	human chr13q21.32	chromosome location	human chr13q21.32	7	1	26134	49	PCDH9
1.310e-02	-4.34	temporoparietal	COSMIC cancer mutations	temporoparietal	61	2	16828	48	RYR3,PARD3
1.312e-02	-4.33	tricarboxylic acid transport	biological process	GO:0006842	5	1	18204	48	SFXN5
1.312e-02	-4.33	otolith morphogenesis	biological process	GO:0032474	5	1	18204	48	LRIG1
1.312e-02	-4.33	propionate metabolic process	biological process	GO:0019541	5	1	18204	48	ACSS1
1.312e-02	-4.33	amygdala development	biological process	GO:0021764	5	1	18204	48	ATP1A2
1.312e-02	-4.33	negative regulation of chondrocyte proliferation	biological process	GO:1902731	5	1	18204	48	BMPR1B
1.312e-02	-4.33	gephyrin clustering involved in postsynaptic density assembly	biological process	GO:0097116	5	1	18204	48	NRXN1
1.312e-02	-4.33	citrate transport	biological process	GO:0015746	5	1	18204	48	SFXN5
1.313e-02	-4.33	transcription regulatory region nucleic acid binding	molecular function	GO:0001067	1487	9	18094	47	SOX5,RORA,GLIS3,NFIA,HIF3A,RFX4,NPAS3,ZBTB20,MEIS2
1.316e-02	-4.33	Protocadherin	interpro domains	IPR013585	5	1	18521	49	PCDH9
1.316e-02	-4.33	Mtc	interpro domains	IPR004686	5	1	18521	49	SFXN5
1.316e-02	-4.33	Vinculin/catenin	interpro domains	IPR006077	5	1	18521	49	CTNNA2
1.316e-02	-4.33	P-type_TPase_V	interpro domains	IPR006544	5	1	18521	49	ATP13A4
1.316e-02	-4.33	Na/HCO3_transpt	interpro domains	IPR003024	5	1	18521	49	SLC4A4
1.316e-02	-4.33	Follistatin/Osteonectin_EGF	interpro domains	IPR015369	5	1	18521	49	SPARCL1
1.316e-02	-4.33	PI_transfer	interpro domains	IPR001666	5	1	18521	49	PITPNC1
1.319e-02	-4.33	skin-scalp-carcinoma-squamous_cell_carcinoma	COSMIC cancer mutations	skin-scalp-carcinoma-squamous_cell_carcinoma	1596	10	16828	48	RORA,LSAMP,GPC5,FGFR3,COL5A3,SOX5,NRXN1,SLC4A4,ATP13A4,ATP1A2
1.323e-02	-4.33	kidney	COSMIC cancer mutations	kidney	15380	48	16828	48	PTGDS,ATP1A2,LRIG1,BMPR1B,ZNRF3,CTNND2,SLC25A18,CAMK2G,NKAIN3,MEIS2,SLC4A4,GPM6A,SOX5,RFX4,PRODH,SORBS1,SPARCL1,SFXN5,PITPNC1,LSAMP,NFIA,ACSS1,AHCYL2,RYR3,SLC1A2,PARD3B,PAMR1,NHSL1,PARD3,COL5A3,FBXL7,GPC5,RORA,HIF3A,NTM,FGFR3,PCDH9,NRXN1,ATP13A4,CDH20,GLIS3,ZBTB20,MSI2,ABLIM1,DTNA,SLC1A3,TNIK,NPAS3
1.336e-02	-4.32	haematopoietic_and_lymphoid_tissue-spleen-lymphoid_neoplasm-marginal_zone_lymphoma	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue-spleen-lymphoid_neoplasm-marginal_zone_lymphoma	323	4	16828	48	MEIS2,PARD3B,SORBS1,NTM
1.347e-02	-4.31	extraskeletal	COSMIC cancer mutations	extraskeletal	903	7	16828	48	PTGDS,ABLIM1,ATP1A2,SPARCL1,LRIG1,NPAS3,FGFR3
1.349e-02	-4.31	collagen binding	molecular function	GO:0005518	68	2	18094	47	COL5A3,SPARCL1
1.354e-02	-4.30	NTRK3 (neurotrophic receptor tyrosine kinase 3)	protein interactions	4916	367	4	19454	49	PARD3,AHCYL2,TNIK,ABLIM1
1.359e-02	-4.30	skin-head_neck-carcinoma-squamous_cell_carcinoma	COSMIC cancer mutations	skin-head_neck-carcinoma-squamous_cell_carcinoma	14191	46	16828	48	PRODH,SORBS1,SPARCL1,SFXN5,NFIA,PITPNC1,LSAMP,AHCYL2,ACSS1,PARD3B,RYR3,SLC1A2,BMPR1B,LRIG1,ATP1A2,CTNND2,SLC25A18,ZNRF3,CAMK2G,SLC4A4,NKAIN3,MEIS2,GPM6A,RFX4,SOX5,NRXN1,PCDH9,ATP13A4,CDH20,GLIS3,ZBTB20,ABLIM1,DTNA,SLC1A3,TNIK,NPAS3,NHSL1,PAMR1,PARD3,COL5A3,FBXL7,GPC5,RORA,HIF3A,NTM,FGFR3
1.369e-02	-4.29	FOLN	pfam domains	PF09289	5	1	17795	49	SPARCL1
1.369e-02	-4.29	IP_trans	pfam domains	PF02121	5	1	17795	49	PITPNC1
1.369e-02	-4.29	SFXNs	pfam domains	PF03820	5	1	17795	49	SFXN5
1.369e-02	-4.29	Vinculin	pfam domains	PF01044	5	1	17795	49	CTNNA2
1.369e-02	-4.29	Protocadherin	pfam domains	PF08374	5	1	17795	49	PCDH9
1.371e-02	-4.29	ALPHACATENIN	prints domains	PR00805	4	1	5227	18	CTNNA2
1.383e-02	-4.28	PAK6 (p21 (RAC1) activated kinase 6)	protein interactions	56924	71	2	19454	49	CAMK2G,AHCYL2
1.383e-02	-4.28	ANK2 (ankyrin 2)	protein interactions	287	71	2	19454	49	TNIK,GPM6A
1.384e-02	-4.28	ORF3a (ORF3a protein)	protein interactions	43740569	789	6	19454	49	ZNRF3,PCDH9,SLC4A4,PARD3,PARD3B,BMPR1B
1.403e-02	-4.27	system process	biological process	GO:0003008	2015	11	18204	48	SLC1A3,ABLIM1,NRXN1,CTNNA2,LRIG1,SLC1A2,MEIS2,RYR3,ATP1A2,DTNA,SLC4A4
1.404e-02	-4.27	CTF_NFI_2	prosite domains	PS51080	4	1	12186	43	NFIA
1.404e-02	-4.27	CTF_NFI_1	prosite domains	PS00349	4	1	12186	43	NFIA
1.418e-02	-4.26	skin-face-other-lichenoid_keratosis	COSMIC cancer mutations	skin-face-other-lichenoid_keratosis	5	1	16828	48	FGFR3
1.418e-02	-4.26	skin-shoulder-other-lichenoid_keratosis	COSMIC cancer mutations	skin-shoulder-other-lichenoid_keratosis	5	1	16828	48	FGFR3
1.418e-02	-4.26	skin-upper_leg-other-lichenoid_keratosis	COSMIC cancer mutations	skin-upper_leg-other-lichenoid_keratosis	5	1	16828	48	FGFR3
1.418e-02	-4.26	skin-neck-other-lichenoid_keratosis	COSMIC cancer mutations	skin-neck-other-lichenoid_keratosis	5	1	16828	48	FGFR3
1.418e-02	-4.26	skin-lower_leg-other-lichenoid_keratosis	COSMIC cancer mutations	skin-lower_leg-other-lichenoid_keratosis	5	1	16828	48	FGFR3
1.418e-02	-4.26	skin-shoulder-other-nevus_sebaceous	COSMIC cancer mutations	skin-shoulder-other-nevus_sebaceous	5	1	16828	48	FGFR3
1.418e-02	-4.26	skin-neck-other-nevus_sebaceous	COSMIC cancer mutations	skin-neck-other-nevus_sebaceous	5	1	16828	48	FGFR3
1.418e-02	-4.26	skin-forearm-other-seborrhoeic_keratosis	COSMIC cancer mutations	skin-forearm-other-seborrhoeic_keratosis	5	1	16828	48	FGFR3
1.418e-02	-4.26	skin-face-other-nevus_sebaceous	COSMIC cancer mutations	skin-face-other-nevus_sebaceous	5	1	16828	48	FGFR3
1.418e-02	-4.26	skin-scalp-other-nevus_sebaceous	COSMIC cancer mutations	skin-scalp-other-nevus_sebaceous	5	1	16828	48	FGFR3
1.418e-02	-4.26	monoclonal_gammopathy_of_undetermined_significance	COSMIC cancer mutations	monoclonal_gammopathy_of_undetermined_significance	5	1	16828	48	FGFR3
1.418e-02	-4.26	syringocystadenoma_papilliferum	COSMIC cancer mutations	syringocystadenoma_papilliferum	5	1	16828	48	FGFR3
1.418e-02	-4.26	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-monoclonal_gammopathy_of_undetermined_significance	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-monoclonal_gammopathy_of_undetermined_significance	5	1	16828	48	FGFR3
1.418e-02	-4.26	skin-breast-other-lichenoid_keratosis	COSMIC cancer mutations	skin-breast-other-lichenoid_keratosis	5	1	16828	48	FGFR3
1.418e-02	-4.26	skin-flank-other-lichenoid_keratosis	COSMIC cancer mutations	skin-flank-other-lichenoid_keratosis	5	1	16828	48	FGFR3
1.418e-02	-4.26	skin-chest-other-lichenoid_keratosis	COSMIC cancer mutations	skin-chest-other-lichenoid_keratosis	5	1	16828	48	FGFR3
1.418e-02	-4.26	skin-forearm-other-lichenoid_keratosis	COSMIC cancer mutations	skin-forearm-other-lichenoid_keratosis	5	1	16828	48	FGFR3
1.418e-02	-4.26	skin-breast-other-nevus_sebaceous	COSMIC cancer mutations	skin-breast-other-nevus_sebaceous	5	1	16828	48	FGFR3
1.418e-02	-4.26	skin-adnexal_tumour-syringocystadenoma_papilliferum	COSMIC cancer mutations	skin-adnexal_tumour-syringocystadenoma_papilliferum	5	1	16828	48	FGFR3
1.418e-02	-4.26	skin-ear-other-nevus_sebaceous	COSMIC cancer mutations	skin-ear-other-nevus_sebaceous	5	1	16828	48	FGFR3
1.418e-02	-4.26	skin-other-lichenoid_keratosis	COSMIC cancer mutations	skin-other-lichenoid_keratosis	5	1	16828	48	FGFR3
1.418e-02	-4.26	skin-upper_back-other-lichenoid_keratosis	COSMIC cancer mutations	skin-upper_back-other-lichenoid_keratosis	5	1	16828	48	FGFR3
1.418e-02	-4.26	skin-upper_arm-other-lichenoid_keratosis	COSMIC cancer mutations	skin-upper_arm-other-lichenoid_keratosis	5	1	16828	48	FGFR3
1.418e-02	-4.26	lichenoid_keratosis	COSMIC cancer mutations	lichenoid_keratosis	5	1	16828	48	FGFR3
1.418e-02	-4.26	skin-hand-other-lichenoid_keratosis	COSMIC cancer mutations	skin-hand-other-lichenoid_keratosis	5	1	16828	48	FGFR3
1.418e-02	-4.26	skin-lower_back-other-lichenoid_keratosis	COSMIC cancer mutations	skin-lower_back-other-lichenoid_keratosis	5	1	16828	48	FGFR3
1.418e-02	-4.26	skin-arm-other-seborrhoeic_keratosis	COSMIC cancer mutations	skin-arm-other-seborrhoeic_keratosis	5	1	16828	48	FGFR3
1.418e-02	-4.26	skin-lower_back-other-nevus_sebaceous	COSMIC cancer mutations	skin-lower_back-other-nevus_sebaceous	5	1	16828	48	FGFR3
1.418e-02	-4.26	skin-hip-other-seborrhoeic_keratosis	COSMIC cancer mutations	skin-hip-other-seborrhoeic_keratosis	5	1	16828	48	FGFR3
1.420e-02	-4.25	DPYSL3 (dihydropyrimidinase like 3)	protein interactions	1809	72	2	19454	49	TNIK,GPM6A
1.420e-02	-4.25	Ppp1cb (protein phosphatase 1 catalytic subunit beta)	protein interactions	19046	72	2	19454	49	PARD3,ABLIM1
1.420e-02	-4.25	PPP3CC (protein phosphatase 3 catalytic subunit gamma)	protein interactions	5533	72	2	19454	49	BMPR1B,PARD3B
1.424e-02	-4.25	EGF	pfam domains	PF00008	66	2	17795	49	NRXN1,PAMR1
1.428e-02	-4.25	animal organ morphogenesis	biological process	GO:0009887	988	7	18204	48	MEIS2,SOX5,ABLIM1,BMPR1B,LRIG1,FGFR3,CTNNA2
1.450e-02	-4.23	marginal_zone_lymphoma	COSMIC cancer mutations	marginal_zone_lymphoma	331	4	16828	48	NTM,SORBS1,PARD3B,MEIS2
1.458e-02	-4.23	pancreas-carcinoma	COSMIC cancer mutations	pancreas-carcinoma	14770	47	16828	48	FGFR3,HIF3A,RORA,NTM,PARD3,NHSL1,PAMR1,COL5A3,FBXL7,GPC5,ABLIM1,NPAS3,SLC1A3,TNIK,ATP13A4,PCDH9,NRXN1,ZBTB20,MSI2,CDH20,GLIS3,SLC4A4,NKAIN3,MEIS2,RFX4,SOX5,GPM6A,BMPR1B,ATP1A2,LRIG1,PTGDS,CAMK2G,CTNND2,SLC25A18,ZNRF3,AHCYL2,ACSS1,PARD3B,RYR3,SLC1A2,SPARCL1,SFXN5,PRODH,SORBS1,NFIA,PITPNC1,LSAMP
1.477e-02	-4.22	-	gene3d domains	6.10.140.620	5	1	14470	43	CAMK2G
1.483e-02	-4.21	oesophagus-middle_third-carcinoma-squamous_cell_carcinoma	COSMIC cancer mutations	oesophagus-middle_third-carcinoma-squamous_cell_carcinoma	3531	17	16828	48	CTNND2,ZBTB20,COL5A3,GPC5,NHSL1,PAMR1,PCDH9,PARD3,SPARCL1,LRIG1,ATP1A2,TNIK,GPM6A,RYR3,SOX5,ABLIM1,SLC4A4
1.488e-02	-4.21	cell-cell contact zone	cellular component	GO:0044291	74	2	19108	48	PCDH9,ATP1A2
1.489e-02	-4.21	UTRN (utrophin)	protein interactions	7402	205	3	19454	49	DTNA,PARD3,FGFR3
1.491e-02	-4.21	middle_third	COSMIC cancer mutations	middle_third	3533	17	16828	48	ZBTB20,COL5A3,GPC5,CTNND2,PARD3,SPARCL1,LRIG1,ATP1A2,NHSL1,PAMR1,PCDH9,SOX5,RYR3,GPM6A,TNIK,SLC4A4,ABLIM1
1.498e-02	-4.20	PAR polarity complex	cellular component	GO:0120157	6	1	19108	48	PARD3
1.502e-02	-4.20	CIBAR2 (CBY1 interacting BAR domain containing 2)	protein interactions	339145	6	1	19454	49	CAMK2G
1.502e-02	-4.20	SLC12A5 (solute carrier family 12 member 5)	protein interactions	57468	6	1	19454	49	GPM6A
1.502e-02	-4.20	SOX11 (SRY-box transcription factor 11)	protein interactions	6664	6	1	19454	49	SOX5
1.502e-02	-4.20	Rhod (ras homolog family member D)	protein interactions	11854	6	1	19454	49	BMPR1B
1.502e-02	-4.20	RSPO3 (R-spondin 3)	protein interactions	84870	6	1	19454	49	ZNRF3
1.502e-02	-4.20	SYTL3 (synaptotagmin like 3)	protein interactions	94120	6	1	19454	49	NRXN1
1.502e-02	-4.20	Fancl (Fanconi anemia, complementation group L)	protein interactions	67030	6	1	19454	49	BMPR1B
1.502e-02	-4.20	Tiam2 (T cell lymphoma invasion and metastasis 2)	protein interactions	24001	6	1	19454	49	DTNA
1.502e-02	-4.20	FGF18 (fibroblast growth factor 18)	protein interactions	8817	6	1	19454	49	FGFR3
1.502e-02	-4.20	FGF6 (fibroblast growth factor 6)	protein interactions	2251	6	1	19454	49	FGFR3
1.502e-02	-4.20	FGF23 (fibroblast growth factor 23)	protein interactions	8074	6	1	19454	49	FGFR3
1.502e-02	-4.20	SOX1 (SRY-box transcription factor 1)	protein interactions	6656	6	1	19454	49	SOX5
1.502e-02	-4.20	Map2k3 (mitogen-activated protein kinase kinase 3)	protein interactions	26397	6	1	19454	49	BMPR1B
1.502e-02	-4.20	CYRIA (CYFIP related Rac1 interactor A)	protein interactions	81553	6	1	19454	49	GPM6A
1.502e-02	-4.20	Itch (itchy, E3 ubiquitin protein ligase)	protein interactions	16396	6	1	19454	49	GLIS3
1.502e-02	-4.20	GDF6 (growth differentiation factor 6)	protein interactions	392255	6	1	19454	49	BMPR1B
1.502e-02	-4.20	Zbtb2 (zinc finger and BTB domain containing 2)	protein interactions	381990	6	1	19454	49	SORBS1
1.502e-02	-4.20	DRP2 (dystrophin related protein 2)	protein interactions	1821	6	1	19454	49	DTNA
1.507e-02	-4.20	non-proteinogenic amino acid metabolic process	biological process	GO:0170041	71	2	18204	48	SLC1A3,PRODH
1.528e-02	-4.18	MAGEA9 (MAGE family member A9)	protein interactions	4108	207	3	19454	49	MEIS2,CAMK2G,NHSL1
1.528e-02	-4.18	neoplasm	COSMIC cancer mutations	neoplasm	14787	47	16828	48	DTNA,ABLIM1,NPAS3,TNIK,SLC1A3,ATP13A4,NRXN1,PCDH9,MSI2,ZBTB20,GLIS3,CDH20,FGFR3,NTM,HIF3A,RORA,PARD3,PAMR1,NHSL1,FBXL7,GPC5,COL5A3,ACSS1,AHCYL2,SLC1A2,RYR3,PARD3B,SFXN5,SPARCL1,SORBS1,PRODH,LSAMP,NFIA,MEIS2,NKAIN3,SLC4A4,RFX4,SOX5,GPM6A,ATP1A2,LRIG1,BMPR1B,PTGDS,CAMK2G,ZNRF3,SLC25A18,CTNND2
1.529e-02	-4.18	alveolar	COSMIC cancer mutations	alveolar	2414	13	16828	48	RYR3,FGFR3,NPAS3,PARD3B,SLC1A3,CDH20,ZNRF3,NFIA,SPARCL1,PARD3,PAMR1,SORBS1,NHSL1
1.529e-02	-4.18	soft_tissue-striated_muscle-rhabdomyosarcoma-alveolar	COSMIC cancer mutations	soft_tissue-striated_muscle-rhabdomyosarcoma-alveolar	2414	13	16828	48	PAMR1,SORBS1,NHSL1,SPARCL1,PARD3,SLC1A3,CDH20,ZNRF3,NFIA,RYR3,FGFR3,PARD3B,NPAS3
1.529e-02	-4.18	bone-femur-other-chondroblastoma	COSMIC cancer mutations	bone-femur-other-chondroblastoma	183	3	16828	48	RYR3,GPC5,PCDH9
1.547e-02	-4.17	C20 prostanoid biosynthesis	BIOCYC pathways	HUMAN_PWY66-374	7	1	902	2	PTGDS
1.547e-02	-4.17	C20 prostanoid biosynthesis	BIOCYC pathways	META_PWY66-374	7	1	902	2	PTGDS
1.548e-02	-4.17	regulation of ATP metabolic process	biological process	GO:1903578	72	2	18204	48	ZBTB20,SLC4A4
1.549e-02	-4.17	amino acid:proton symporter activity	molecular function	GO:0005280	6	1	18094	47	SLC25A18
1.549e-02	-4.17	steroid hormone binding	molecular function	GO:1990239	6	1	18094	47	ATP1A2
1.549e-02	-4.17	sodium:bicarbonate symporter activity	molecular function	GO:0008510	6	1	18094	47	SLC4A4
1.549e-02	-4.17	calcium-induced calcium release activity	molecular function	GO:0048763	6	1	18094	47	RYR3
1.560e-02	-4.16	axonogenesis	biological process	GO:0007409	366	4	18204	48	BMPR1B,PARD3,CTNNA2,NRXN1
1.562e-02	-4.16	ovary-carcinoma-serous_carcinoma	COSMIC cancer mutations	ovary-carcinoma-serous_carcinoma	10710	38	16828	48	ATP13A4,SFXN5,SORBS1,NRXN1,PCDH9,ZBTB20,MSI2,CDH20,LSAMP,GLIS3,DTNA,AHCYL2,ACSS1,NPAS3,PARD3B,RYR3,SLC1A2,SLC1A3,TNIK,PARD3,BMPR1B,ATP1A2,LRIG1,NHSL1,PAMR1,PTGDS,COL5A3,FBXL7,GPC5,CAMK2G,CTNND2,ZNRF3,SLC4A4,MEIS2,FGFR3,SOX5,RORA,NTM
1.565e-02	-4.16	sarcoplasmic reticulum	cellular component	GO:0016529	76	2	19108	48	CAMK2G,RYR3
1.572e-02	-4.15	asymmetric neuroblast division	biological process	GO:0055059	6	1	18204	48	SOX5
1.572e-02	-4.15	fused antrum stage	biological process	GO:0048165	6	1	18204	48	BMPR1B
1.572e-02	-4.15	gamma-aminobutyric acid biosynthetic process	biological process	GO:0009449	6	1	18204	48	SLC1A3
1.572e-02	-4.15	postsynaptic density protein 95 clustering	biological process	GO:0097119	6	1	18204	48	NRXN1
1.572e-02	-4.15	imitative learning	biological process	GO:0098596	6	1	18204	48	NRXN1
1.572e-02	-4.15	vocal learning	biological process	GO:0042297	6	1	18204	48	NRXN1
1.577e-02	-4.15	RIH_assoc-dom	interpro domains	IPR013662	6	1	18521	49	RYR3
1.577e-02	-4.15	P-type_ATPase_IIC	interpro domains	IPR005775	6	1	18521	49	ATP1A2
1.577e-02	-4.15	EF-hand_dom_typ1	interpro domains	IPR015153	6	1	18521	49	DTNA
1.577e-02	-4.15	Syndecan/Neurexin_dom	interpro domains	IPR027789	6	1	18521	49	NRXN1
1.577e-02	-4.15	RIH_dom	interpro domains	IPR000699	6	1	18521	49	RYR3
1.577e-02	-4.15	EF-hand_dom_typ2	interpro domains	IPR015154	6	1	18521	49	DTNA
1.577e-02	-4.15	RyR/IP3R_RIH_dom_sf	interpro domains	IPR035910	6	1	18521	49	RYR3
1.577e-02	-4.15	Ins145_P3_rcpt	interpro domains	IPR014821	6	1	18521	49	RYR3
1.577e-02	-4.15	Glypican_CS	interpro domains	IPR019803	6	1	18521	49	GPC5
1.577e-02	-4.15	Glypican	interpro domains	IPR001863	6	1	18521	49	GPC5
1.577e-02	-4.15	GLI-like	interpro domains	IPR043359	6	1	18521	49	GLIS3
1.577e-02	-4.15	Ryanodine_IP3_receptor	interpro domains	IPR015925	6	1	18521	49	RYR3
1.585e-02	-4.14	Endochondral Ossification	WikiPathways	WP474	65	2	5310	16	SOX5,FGFR3
1.587e-02	-4.14	ABI1 (abl interactor 1)	protein interactions	10006	210	3	19454	49	NHSL1,SLC1A3,SORBS1
1.588e-02	-4.14	regulation of cartilage development	biological process	GO:0061035	73	2	18204	48	SOX5,BMPR1B
1.607e-02	-4.13	CDK6 (cyclin dependent kinase 6)	protein interactions	1021	211	3	19454	49	SOX5,FGFR3,SORBS1
1.615e-02	-4.13	prostate-carcinoma-adenocarcinoma	COSMIC cancer mutations	prostate-carcinoma-adenocarcinoma	12379	42	16828	48	SPARCL1,ATP13A4,SFXN5,PRODH,PCDH9,NRXN1,SORBS1,ZBTB20,NFIA,PITPNC1,LSAMP,CDH20,GLIS3,AHCYL2,ABLIM1,ACSS1,PARD3B,NPAS3,RYR3,SLC1A2,SLC1A3,TNIK,PARD3,BMPR1B,ATP1A2,LRIG1,NHSL1,PAMR1,COL5A3,GPC5,FBXL7,CTNND2,SLC25A18,NKAIN3,MEIS2,FGFR3,SOX5,RFX4,RORA,HIF3A,NTM,GPM6A
1.641e-02	-4.11	HAD_sf	interpro domains	IPR023214	74	2	18521	49	ATP13A4,ATP1A2
1.641e-02	-4.11	Ins145_P3_rec	pfam domains	PF08709	6	1	17795	49	RYR3
1.641e-02	-4.11	Syndecan	pfam domains	PF01034	6	1	17795	49	NRXN1
1.641e-02	-4.11	Glypican	pfam domains	PF01153	6	1	17795	49	GPC5
1.641e-02	-4.11	EF-hand_3	pfam domains	PF09069	6	1	17795	49	DTNA
1.641e-02	-4.11	RIH_assoc	pfam domains	PF08454	6	1	17795	49	RYR3
1.641e-02	-4.11	EF-hand_2	pfam domains	PF09068	6	1	17795	49	DTNA
1.641e-02	-4.11	RYDR_ITPR	pfam domains	PF01365	6	1	17795	49	RYR3
1.641e-02	-4.11	Bile secretion	KEGG pathways	ko04976	71	2	7161	20	ATP1A2,SLC4A4
1.641e-02	-4.11	Bile secretion	KEGG pathways	hsa04976	71	2	7161	20	SLC4A4,ATP1A2
1.652e-02	-4.10	KRTAP19-6 (keratin associated protein 19-6)	protein interactions	337973	78	2	19454	49	MEIS2,SLC25A18
1.660e-02	-4.10	membrane	cellular component	GO:0016020	9220	31	19108	48	PARD3,PRODH,DTNA,SLC4A4,TNIK,PTGDS,LRIG1,SLC25A18,PCDH9,SLC1A3,CTNND2,NRXN1,ZNRF3,FGFR3,NKAIN3,BMPR1B,PARD3B,RYR3,HIF3A,GPC5,GPM6A,SORBS1,SFXN5,CTNNA2,LSAMP,CAMK2G,NTM,CDH20,ATP1A2,ATP13A4,SLC1A2
1.668e-02	-4.09	sequence-specific double-stranded DNA binding	molecular function	GO:1990837	1547	9	18094	47	ZBTB20,MEIS2,HIF3A,RFX4,NPAS3,GLIS3,NFIA,SOX5,RORA
1.675e-02	-4.09	human chr4q22.3	chromosome location	human chr4q22.3	9	1	26134	49	BMPR1B
1.691e-02	-4.08	plasma membrane protein complex	cellular component	GO:0098797	600	5	19108	48	CTNNA2,SORBS1,BMPR1B,ATP1A2,CDH20
1.700e-02	-4.07	lentiginous_nevus	COSMIC cancer mutations	lentiginous_nevus	6	1	16828	48	FGFR3
1.700e-02	-4.07	skin-in_situ_epithelial_neoplasm-Bowen_disease	COSMIC cancer mutations	skin-in_situ_epithelial_neoplasm-Bowen_disease	6	1	16828	48	FGFR3
1.700e-02	-4.07	skin-abdomen-other-seborrhoeic_keratosis	COSMIC cancer mutations	skin-abdomen-other-seborrhoeic_keratosis	6	1	16828	48	FGFR3
1.700e-02	-4.07	skin-head_neck-epidermal_nevus	COSMIC cancer mutations	skin-head_neck-epidermal_nevus	6	1	16828	48	FGFR3
1.700e-02	-4.07	skin-back-other-seborrhoeic_keratosis	COSMIC cancer mutations	skin-back-other-seborrhoeic_keratosis	6	1	16828	48	FGFR3
1.700e-02	-4.07	skin-upper_leg-other-seborrhoeic_keratosis	COSMIC cancer mutations	skin-upper_leg-other-seborrhoeic_keratosis	6	1	16828	48	FGFR3
1.700e-02	-4.07	skin-lower_leg-epidermal_nevus	COSMIC cancer mutations	skin-lower_leg-epidermal_nevus	6	1	16828	48	FGFR3
1.700e-02	-4.07	skin-adnexal_tumour-trichoblastoma	COSMIC cancer mutations	skin-adnexal_tumour-trichoblastoma	6	1	16828	48	FGFR3
1.700e-02	-4.07	skin-lower_back-other-seborrhoeic_keratosis	COSMIC cancer mutations	skin-lower_back-other-seborrhoeic_keratosis	6	1	16828	48	FGFR3
1.700e-02	-4.07	skin-epidermal_nevus	COSMIC cancer mutations	skin-epidermal_nevus	6	1	16828	48	FGFR3
1.700e-02	-4.07	collecting_duct_carcinoma	COSMIC cancer mutations	collecting_duct_carcinoma	6	1	16828	48	FGFR3
1.700e-02	-4.07	skin-flank-other-seborrhoeic_keratosis	COSMIC cancer mutations	skin-flank-other-seborrhoeic_keratosis	6	1	16828	48	FGFR3
1.700e-02	-4.07	skin-benign_melanocytic_nevus-lentiginous_nevus	COSMIC cancer mutations	skin-benign_melanocytic_nevus-lentiginous_nevus	6	1	16828	48	FGFR3
1.700e-02	-4.07	skin-arm-epidermal_nevus	COSMIC cancer mutations	skin-arm-epidermal_nevus	6	1	16828	48	FGFR3
1.700e-02	-4.07	kidney-carcinoma-collecting_duct_carcinoma	COSMIC cancer mutations	kidney-carcinoma-collecting_duct_carcinoma	6	1	16828	48	FGFR3
1.700e-02	-4.07	skin-face-other-seborrhoeic_keratosis	COSMIC cancer mutations	skin-face-other-seborrhoeic_keratosis	6	1	16828	48	FGFR3
1.700e-02	-4.07	skin-in_situ_epithelial_neoplasm-actinic_keratosis	COSMIC cancer mutations	skin-in_situ_epithelial_neoplasm-actinic_keratosis	6	1	16828	48	FGFR3
1.700e-02	-4.07	autonomic_ganglia-paraganglioma-benign	COSMIC cancer mutations	autonomic_ganglia-paraganglioma-benign	6	1	16828	48	NHSL1
1.700e-02	-4.07	skin-trunk-epidermal_nevus	COSMIC cancer mutations	skin-trunk-epidermal_nevus	6	1	16828	48	FGFR3
1.711e-02	-4.07	NAHCO3TRSPRT	prints domains	PR01232	5	1	5227	18	SLC4A4
1.711e-02	-4.07	PITRANSFER	prints domains	PR00391	5	1	5227	18	PITPNC1
1.715e-02	-4.07	Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour	COSMIC cancer mutations	Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour	7434	29	16828	48	SLC4A4,NKAIN3,FGFR3,SOX5,RORA,HIF3A,PARD3,ATP1A2,LRIG1,PTGDS,PAMR1,COL5A3,CAMK2G,CTNND2,DTNA,ACSS1,ABLIM1,PARD3B,NPAS3,RYR3,TNIK,SLC1A3,ATP13A4,SPARCL1,SORBS1,NRXN1,PRODH,ZBTB20,GLIS3
1.731e-02	-4.06	GFAP (glial fibrillary acidic protein)	protein interactions	2670	217	3	19454	49	RORA,ABLIM1,NKAIN3
1.743e-02	-4.05	Protein_kinase_ATP_BS	interpro domains	IPR017441	377	4	18521	49	FGFR3,TNIK,BMPR1B,CAMK2G
1.750e-02	-4.05	SASH3 (SAM and SH3 domain containing 3)	protein interactions	54440	7	1	19454	49	BMPR1B
1.750e-02	-4.05	Ahcyl1 (S-adenosylhomocysteine hydrolase-like 1)	protein interactions	229709	7	1	19454	49	AHCYL2
1.750e-02	-4.05	Fbxo3 (F-box protein 3)	protein interactions	57443	7	1	19454	49	BMPR1B
1.750e-02	-4.05	Smad7 (SMAD family member 7)	protein interactions	17131	7	1	19454	49	BMPR1B
1.750e-02	-4.05	Smurf1 (SMAD specific E3 ubiquitin protein ligase 1)	protein interactions	75788	7	1	19454	49	GLIS3
1.750e-02	-4.05	FGF5 (fibroblast growth factor 5)	protein interactions	2250	7	1	19454	49	FGFR3
1.750e-02	-4.05	ZBTB45 (zinc finger and BTB domain containing 45)	protein interactions	84878	7	1	19454	49	ZBTB20
1.750e-02	-4.05	ABCC12 (ATP binding cassette subfamily C member 12)	protein interactions	94160	7	1	19454	49	NPAS3
1.750e-02	-4.05	RGMB (repulsive guidance molecule BMP co-receptor b)	protein interactions	285704	7	1	19454	49	BMPR1B
1.750e-02	-4.05	Uhmk1 (U2AF homology motif (UHM) kinase 1)	protein interactions	16589	7	1	19454	49	BMPR1B
1.757e-02	-4.04	BMP signaling pathway	biological process	GO:0030509	77	2	18204	48	BMPR1B,NFIA
1.757e-02	-4.04	regulation of synaptic transmission, glutamatergic	biological process	GO:0051966	77	2	18204	48	NRXN1,ATP1A2
1.770e-02	-4.03	IP3 receptor type 1 binding core, RIH domain	gene3d domains	1.25.10.30	6	1	14470	43	RYR3
1.774e-02	-4.03	ARNT2 (aryl hydrocarbon receptor nuclear translocator 2)	protein interactions	9915	81	2	19454	49	MEIS2,NPAS3
1.779e-02	-4.03	Neuronal System	REACTOME pathways	R-HSA-112316	349	4	10285	30	SLC1A2,SLC1A3,CAMK2G,NRXN1
1.782e-02	-4.03	eye development	biological process	GO:0001654	381	4	18204	48	NFIA,GPM6A,MEIS2,BMPR1B
1.783e-02	-4.03	other	COSMIC cancer mutations	other	14843	47	16828	48	CDH20,GLIS3,ZBTB20,MSI2,PCDH9,NRXN1,ATP13A4,SLC1A3,TNIK,NPAS3,ABLIM1,DTNA,COL5A3,FBXL7,GPC5,NHSL1,PAMR1,PARD3,RORA,HIF3A,NTM,FGFR3,NFIA,LSAMP,PRODH,SORBS1,SPARCL1,SFXN5,PARD3B,RYR3,SLC1A2,AHCYL2,ACSS1,CTNND2,SLC25A18,ZNRF3,CAMK2G,PTGDS,BMPR1B,LRIG1,ATP1A2,GPM6A,SOX5,RFX4,SLC4A4,NKAIN3,MEIS2
1.795e-02	-4.02	anion binding	molecular function	GO:0043168	2412	12	18094	47	PITPNC1,ATP13A4,PTGDS,CAMK2G,ATP1A2,ACSS1,FGFR3,SLC1A3,BMPR1B,PARD3,PRODH,TNIK
1.800e-02	-4.02	regulation of glucose transmembrane transport	biological process	GO:0010827	78	2	18204	48	SORBS1,SLC1A2
1.801e-02	-4.02	sensory organ development	biological process	GO:0007423	581	5	18204	48	MEIS2,BMPR1B,LRIG1,NFIA,GPM6A
1.804e-02	-4.01	P-type sodium:potassium-exchanging transporter activity	molecular function	GO:0005391	7	1	18094	47	ATP1A2
1.804e-02	-4.01	P-type sodium transporter activity	molecular function	GO:0008554	7	1	18094	47	ATP1A2
1.804e-02	-4.01	calcium-dependent protein serine/threonine phosphatase activity	molecular function	GO:0004723	7	1	18094	47	CAMK2G
1.804e-02	-4.01	phosphatidic acid transfer activity	molecular function	GO:1990050	7	1	18094	47	PITPNC1
1.806e-02	-4.01	YWHAH (tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein eta)	protein interactions	7533	1083	7	19454	49	PARD3,PITPNC1,ABLIM1,NHSL1,PARD3B,CAMK2G,SORBS1
1.812e-02	-4.01	HAD-like_sf	interpro domains	IPR036412	78	2	18521	49	ATP1A2,ATP13A4
1.816e-02	-4.01	GSC (goosecoid homeobox)	protein interactions	145258	82	2	19454	49	SOX5,NFIA
1.820e-02	-4.01	Gastric acid secretion	KEGG pathways	hsa04971	75	2	7161	20	CAMK2G,ATP1A2
1.820e-02	-4.01	Gastric acid secretion	KEGG pathways	ko04971	75	2	7161	20	CAMK2G,ATP1A2
1.824e-02	-4.00	somatodendritic compartment	cellular component	GO:0036477	842	6	19108	48	NRXN1,ATP1A2,SLC1A3,BMPR1B,GPM6A,CTNND2
1.832e-02	-4.00	negative regulation of non-canonical Wnt signaling pathway	biological process	GO:2000051	7	1	18204	48	ZNRF3
1.832e-02	-4.00	glial cell fate specification	biological process	GO:0021780	7	1	18204	48	NFIA
1.832e-02	-4.00	cellular response to magnesium ion	biological process	GO:0071286	7	1	18204	48	RYR3
1.832e-02	-4.00	observational learning	biological process	GO:0098597	7	1	18204	48	NRXN1
1.832e-02	-4.00	regulation of cardiac muscle myoblast proliferation	biological process	GO:0110022	7	1	18204	48	MEIS2
1.832e-02	-4.00	regulation of male germ cell proliferation	biological process	GO:2000254	7	1	18204	48	PTGDS
1.832e-02	-4.00	S-adenosylmethionine cycle	biological process	GO:0033353	7	1	18204	48	AHCYL2
1.832e-02	-4.00	negative regulation of Arp2/3 complex-mediated actin nucleation	biological process	GO:0034316	7	1	18204	48	CTNNA2
1.838e-02	-4.00	Alpha-catenin/vinculin-like_sf	interpro domains	IPR036723	7	1	18521	49	CTNNA2
1.838e-02	-4.00	Plakophilin/d_Catenin	interpro domains	IPR028435	7	1	18521	49	CTNND2
1.838e-02	-4.00	SPARC/Testican_Ca-bd-dom	interpro domains	IPR019577	7	1	18521	49	SPARCL1
1.838e-02	-4.00	GS_dom	interpro domains	IPR003605	7	1	18521	49	BMPR1B
1.844e-02	-3.99	visual system development	biological process	GO:0150063	385	4	18204	48	NFIA,GPM6A,MEIS2,BMPR1B
1.847e-02	-3.99	FBXO2 (F-box protein 2)	protein interactions	26232	403	4	19454	49	PCDH9,LRIG1,NTM,FGFR3
1.848e-02	-3.99	caveola	cellular component	GO:0005901	83	2	19108	48	ATP1A2,SORBS1
1.858e-02	-3.99	SYT1 (synaptotagmin 1)	protein interactions	6857	83	2	19454	49	NRXN1,GPM6A
1.858e-02	-3.99	DNM3 (dynamin 3)	protein interactions	26052	83	2	19454	49	FGFR3,GPM6A
1.860e-02	-3.98	human chr9p24.2	chromosome location	human chr9p24.2	10	1	26134	49	GLIS3
1.878e-02	-3.97	transmembrane receptor protein kinase activity	molecular function	GO:0019199	81	2	18094	47	BMPR1B,FGFR3
1.894e-02	-3.97	haematopoietic_and_lymphoid_tissue-lymph_node-lymphoid_neoplasm-diffuse_large_B_cell_lymphoma	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue-lymph_node-lymphoid_neoplasm-diffuse_large_B_cell_lymphoma	748	6	16828	48	DTNA,PARD3,SOX5,CTNND2,SLC1A3,ACSS1
1.912e-02	-3.96	SPARC_Ca_bdg	pfam domains	PF10591	7	1	17795	49	SPARCL1
1.912e-02	-3.96	TGF_beta_GS	pfam domains	PF08515	7	1	17795	49	BMPR1B
1.918e-02	-3.95	leg	COSMIC cancer mutations	leg	969	7	16828	48	SLC4A4,ATP13A4,FGFR3,ZBTB20,COL5A3,HIF3A,NTM
1.926e-02	-3.95	endometrium-carcinoma-serous_carcinoma	COSMIC cancer mutations	endometrium-carcinoma-serous_carcinoma	1442	9	16828	48	NRXN1,SORBS1,SLC4A4,PARD3,LSAMP,TNIK,CTNND2,RYR3,GPC5
1.940e-02	-3.94	sensory system development	biological process	GO:0048880	391	4	18204	48	GPM6A,NFIA,BMPR1B,MEIS2
1.965e-02	-3.93	glutamatergic synapse	cellular component	GO:0098978	412	4	19108	48	SPARCL1,GPM6A,TNIK,SLC1A2
1.975e-02	-3.92	stress fiber	cellular component	GO:0001725	86	2	19108	48	SORBS1,ABLIM1
1.975e-02	-3.92	contractile actin filament bundle	cellular component	GO:0097517	86	2	19108	48	ABLIM1,SORBS1
1.980e-02	-3.92	trichilemmoma	COSMIC cancer mutations	trichilemmoma	7	1	16828	48	FGFR3
1.980e-02	-3.92	skin-shoulder-other-seborrhoeic_keratosis	COSMIC cancer mutations	skin-shoulder-other-seborrhoeic_keratosis	7	1	16828	48	FGFR3
1.980e-02	-3.92	urinary_tract-carcinoma-transitional_cell_carcinoma	COSMIC cancer mutations	urinary_tract-carcinoma-transitional_cell_carcinoma	7	1	16828	48	FGFR3
1.980e-02	-3.92	skin-other-nevus_sebaceous	COSMIC cancer mutations	skin-other-nevus_sebaceous	7	1	16828	48	FGFR3
1.980e-02	-3.92	skin-neck-other-seborrhoeic_keratosis	COSMIC cancer mutations	skin-neck-other-seborrhoeic_keratosis	7	1	16828	48	FGFR3
1.980e-02	-3.92	skin-benign_melanocytic_nevus-compound	COSMIC cancer mutations	skin-benign_melanocytic_nevus-compound	7	1	16828	48	FGFR3
1.980e-02	-3.92	skin-adnexal_tumour-trichilemmoma	COSMIC cancer mutations	skin-adnexal_tumour-trichilemmoma	7	1	16828	48	FGFR3
1.980e-02	-3.92	skin-benign_melanocytic_nevus-intradermal	COSMIC cancer mutations	skin-benign_melanocytic_nevus-intradermal	7	1	16828	48	FGFR3
1.980e-02	-3.92	skin-chest-other-seborrhoeic_keratosis	COSMIC cancer mutations	skin-chest-other-seborrhoeic_keratosis	7	1	16828	48	FGFR3
1.980e-02	-3.92	nevus_sebaceous	COSMIC cancer mutations	nevus_sebaceous	7	1	16828	48	FGFR3
1.980e-02	-3.92	skin-face-adnexal_tumour-malignant_adnexal_tumour	COSMIC cancer mutations	skin-face-adnexal_tumour-malignant_adnexal_tumour	7	1	16828	48	FGFR3
1.986e-02	-3.92	SYNJ1 (synaptojanin 1)	protein interactions	8867	86	2	19454	49	SORBS1,GPM6A
1.986e-02	-3.92	EGLN1 (egl-9 family hypoxia inducible factor 1)	protein interactions	54583	86	2	19454	49	HIF3A,FGFR3
1.992e-02	-3.92	zonula adherens	cellular component	GO:0005915	8	1	19108	48	SORBS1
1.992e-02	-3.92	HFE-transferrin receptor complex	cellular component	GO:1990712	8	1	19108	48	BMPR1B
1.998e-02	-3.91	BMP15 (bone morphogenetic protein 15)	protein interactions	9210	8	1	19454	49	BMPR1B
1.998e-02	-3.91	LHB (luteinizing hormone subunit beta)	protein interactions	3972	8	1	19454	49	NTM
1.998e-02	-3.91	Rps27a (ribosomal protein S27A)	protein interactions	78294	8	1	19454	49	BMPR1B
1.998e-02	-3.91	INSM1 (INSM transcriptional repressor 1)	protein interactions	3642	8	1	19454	49	SORBS1
1.998e-02	-3.91	SCT (secretin)	protein interactions	6343	8	1	19454	49	MEIS2
1.998e-02	-3.91	PTGER1 (prostaglandin E receptor 1)	protein interactions	5731	8	1	19454	49	PTGDS
1.998e-02	-3.91	Rasd2 (RASD family, member 2)	protein interactions	75141	8	1	19454	49	BMPR1B
2.014e-02	-3.91	Ig_sub	interpro domains	IPR003599	394	4	18521	49	FGFR3,LRIG1,LSAMP,NTM
2.016e-02	-3.90	ConA-like_dom_sf	interpro domains	IPR013320	219	3	18521	49	COL5A3,RYR3,NRXN1
2.016e-02	-3.90	DST (dystonin)	protein interactions	667	230	3	19454	49	ATP1A2,TNIK,PARD3
2.025e-02	-3.90	FGFR3b ligand binding and activation	REACTOME pathways	R-HSA-190371	7	1	10285	30	FGFR3
2.029e-02	-3.90	ZNF608 (zinc finger protein 608)	protein interactions	57507	87	2	19454	49	SOX5,NFIA
2.031e-02	-3.90	cell-cell signaling	biological process	GO:0007267	822	6	18204	48	SLC1A2,SLC1A3,CAMK2G,FGFR3,NRXN1,DTNA
2.035e-02	-3.89	HAD superfamily/HAD-like	gene3d domains	3.40.50.1000	74	2	14470	43	ATP13A4,ATP1A2
2.049e-02	-3.89	ACTIVIN2R	prints domains	PR00653	6	1	5227	18	BMPR1B
2.060e-02	-3.88	sodium ion binding	molecular function	GO:0031402	8	1	18094	47	ATP1A2
2.060e-02	-3.88	P-type potassium transmembrane transporter activity	molecular function	GO:0008556	8	1	18094	47	ATP1A2
2.060e-02	-3.88	BMP receptor activity	molecular function	GO:0098821	8	1	18094	47	BMPR1B
2.060e-02	-3.88	glutamate binding	molecular function	GO:0016595	8	1	18094	47	SLC1A3
2.069e-02	-3.88	regulation of sodium ion transport	biological process	GO:0002028	84	2	18204	48	NKAIN3,ATP1A2
2.073e-02	-3.88	RAP2A (RAP2A, member of RAS oncogene family)	protein interactions	5911	88	2	19454	49	TNIK,BMPR1B
2.090e-02	-3.87	cell proliferation in external granule layer	biological process	GO:0021924	8	1	18204	48	RORA
2.090e-02	-3.87	cerebellar granule cell precursor proliferation	biological process	GO:0021930	8	1	18204	48	RORA
2.090e-02	-3.87	cell proliferation in hindbrain	biological process	GO:0021534	8	1	18204	48	RORA
2.090e-02	-3.87	regulation of germ cell proliferation	biological process	GO:1905936	8	1	18204	48	PTGDS
2.090e-02	-3.87	gamma-aminobutyric acid metabolic process	biological process	GO:0009448	8	1	18204	48	SLC1A3
2.090e-02	-3.87	regulation of L-glutamate import across plasma membrane	biological process	GO:0002036	8	1	18204	48	ATP1A2
2.090e-02	-3.87	regulation of synapse structural plasticity	biological process	GO:0051823	8	1	18204	48	CTNNA2
2.097e-02	-3.86	Villin_headpiece	interpro domains	IPR003128	8	1	18521	49	ABLIM1
2.097e-02	-3.86	RFX-like	interpro domains	IPR039779	8	1	18521	49	RFX4
2.097e-02	-3.86	Villin_headpiece_dom_sf	interpro domains	IPR036886	8	1	18521	49	ABLIM1
2.099e-02	-3.86	GLYPICAN	prosite domains	PS01207	6	1	12186	43	GPC5
2.109e-02	-3.86	HMG20A (high mobility group 20A)	protein interactions	10363	234	3	19454	49	NFIA,SOX5,DTNA
2.110e-02	-3.86	cell differentiation	biological process	GO:0030154	3645	16	18204	48	NTM,RORA,TNIK,MSI2,FGFR3,PARD3,BMPR1B,CAMK2G,NHSL1,NRXN1,CTNNA2,CTNND2,SLC1A3,GPM6A,SOX5,NFIA
2.117e-02	-3.85	PLEKHA2 (pleckstrin homology domain containing A2)	protein interactions	59339	89	2	19454	49	DTNA,AHCYL2
2.125e-02	-3.85	cellular developmental process	biological process	GO:0048869	3648	16	18204	48	BMPR1B,CAMK2G,NHSL1,NRXN1,CTNNA2,CTNND2,SLC1A3,GPM6A,SOX5,NFIA,RORA,NTM,TNIK,MSI2,FGFR3,PARD3
2.162e-02	-3.83	FGFR1OP2 (FGFR1 oncogene partner 2)	protein interactions	26127	90	2	19454	49	TNIK,CAMK2G
2.180e-02	-3.83	CAMK2A (calcium/calmodulin dependent protein kinase II alpha)	protein interactions	815	237	3	19454	49	CAMK2G,GPM6A,SOX5
2.182e-02	-3.82	VHP	pfam domains	PF02209	8	1	17795	49	ABLIM1
2.207e-02	-3.81	DGUOK (deoxyguanosine kinase)	protein interactions	1716	91	2	19454	49	NTM,GPM6A
2.207e-02	-3.81	SOS1 (SOS Ras/Rac guanine nucleotide exchange factor 1)	protein interactions	6654	91	2	19454	49	SORBS1,TNIK
2.209e-02	-3.81	associative learning	biological process	GO:0008306	87	2	18204	48	ATP1A2,MEIS2
2.218e-02	-3.81	skeletal system morphogenesis	biological process	GO:0048705	228	3	18204	48	FGFR3,SOX5,BMPR1B
2.224e-02	-3.81	bone-fibula-Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour	COSMIC cancer mutations	bone-fibula-Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour	377	4	16828	48	NRXN1,PRODH,FGFR3,COL5A3
2.224e-02	-3.81	HNRNPL (heterogeneous nuclear ribonucleoprotein L)	protein interactions	3191	1958	10	19454	49	ZBTB20,PARD3,MSI2,NFIA,FGFR3,PARD3B,BMPR1B,AHCYL2,DTNA,ABLIM1
2.228e-02	-3.80	forebrain development	biological process	GO:0030900	408	4	18204	48	SLC1A2,PCDH9,ATP1A2,RFX4
2.239e-02	-3.80	flotillin complex	cellular component	GO:0016600	9	1	19108	48	SORBS1
2.241e-02	-3.80	actomyosin	cellular component	GO:0042641	92	2	19108	48	ABLIM1,SORBS1
2.245e-02	-3.80	Tyw3 (tRNA-yW synthesizing protein 3 homolog (S. cerevisiae))	protein interactions	209584	9	1	19454	49	CTNNA2
2.245e-02	-3.80	GUSBP1 (GUSB pseudogene 1)	protein interactions	728411	9	1	19454	49	FGFR3
2.245e-02	-3.80	CAMK2N1 (calcium/calmodulin dependent protein kinase II inhibitor 1)	protein interactions	55450	9	1	19454	49	CAMK2G
2.245e-02	-3.80	KLB (klotho beta)	protein interactions	152831	9	1	19454	49	FGFR3
2.245e-02	-3.80	VEPH1 (ventricular zone expressed PH domain containing 1)	protein interactions	79674	9	1	19454	49	BMPR1B
2.251e-02	-3.79	lung-carcinoma-bronchioloalveolar_adenocarcinoma	COSMIC cancer mutations	lung-carcinoma-bronchioloalveolar_adenocarcinoma	778	6	16828	48	TNIK,CTNND2,CAMK2G,SOX5,BMPR1B,FGFR3
2.251e-02	-3.79	bronchioloalveolar_adenocarcinoma	COSMIC cancer mutations	bronchioloalveolar_adenocarcinoma	778	6	16828	48	CTNND2,TNIK,FGFR3,BMPR1B,SOX5,CAMK2G
2.253e-02	-3.79	POTEI (POTE ankyrin domain family member I)	protein interactions	653269	92	2	19454	49	FGFR3,DTNA
2.253e-02	-3.79	FNTA (farnesyltransferase, CAAX box, subunit alpha)	protein interactions	2339	92	2	19454	49	TNIK,FGFR3
2.260e-02	-3.79	cervix-in_situ_neoplasm-cervical_intraepithelial_neoplasia_Grade_I	COSMIC cancer mutations	cervix-in_situ_neoplasm-cervical_intraepithelial_neoplasia_Grade_I	8	1	16828	48	FGFR3
2.260e-02	-3.79	junctional	COSMIC cancer mutations	junctional	8	1	16828	48	FGFR3
2.260e-02	-3.79	urinary_tract-ureter-carcinoma-transitional_cell_carcinoma	COSMIC cancer mutations	urinary_tract-ureter-carcinoma-transitional_cell_carcinoma	8	1	16828	48	FGFR3
2.260e-02	-3.79	trichoblastoma	COSMIC cancer mutations	trichoblastoma	8	1	16828	48	FGFR3
2.260e-02	-3.79	cervical_intraepithelial_neoplasia_Grade_I	COSMIC cancer mutations	cervical_intraepithelial_neoplasia_Grade_I	8	1	16828	48	FGFR3
2.260e-02	-3.79	actinic_keratosis	COSMIC cancer mutations	actinic_keratosis	8	1	16828	48	FGFR3
2.268e-02	-3.79	response to organic cyclic compound	biological process	GO:0014070	843	6	18204	48	RORA,ATP1A2,RYR3,SLC1A2,PTGDS,SLC1A3
2.288e-02	-3.78	upper_aerodigestive_tract-pharynx-carcinoma-squamous_cell_carcinoma	COSMIC cancer mutations	upper_aerodigestive_tract-pharynx-carcinoma-squamous_cell_carcinoma	1485	9	16828	48	PARD3B,FGFR3,NPAS3,GPC5,RYR3,PRODH,PCDH9,SORBS1,DTNA
2.299e-02	-3.77	ARHGEF6 (Rac/Cdc42 guanine nucleotide exchange factor 6)	protein interactions	9459	93	2	19454	49	ABLIM1,BMPR1B
2.299e-02	-3.77	ODR4 (odr-4 GPCR localization factor homolog)	protein interactions	54953	93	2	19454	49	LRIG1,GPM6A
2.299e-02	-3.77	MPDZ (multiple PDZ domain crumbs cell polarity complex component)	protein interactions	8777	93	2	19454	49	PARD3,FGFR3
2.299e-02	-3.77	behavior	biological process	GO:0007610	619	5	18204	48	SLC1A3,NRXN1,ATP1A2,SLC1A2,MEIS2
2.302e-02	-3.77	YWHAZ (tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein zeta)	protein interactions	7534	1138	7	19454	49	PARD3,PITPNC1,CAMK2G,SORBS1,PARD3B,ABLIM1,NHSL1
2.303e-02	-3.77	Insulin secretion	KEGG pathways	hsa04911	85	2	7161	20	ATP1A2,CAMK2G
2.305e-02	-3.77	positive regulation of lipid biosynthetic process	biological process	GO:0046889	89	2	18204	48	SORBS1,ZBTB20
2.311e-02	-3.77	Release of Hh-Np from the secreting cell	REACTOME pathways	R-HSA-5362798	8	1	10285	30	GPC5
2.314e-02	-3.77	L-aspartate transmembrane transporter activity	molecular function	GO:0015183	9	1	18094	47	SLC25A18
2.323e-02	-3.76	lipid binding	molecular function	GO:0008289	861	6	18094	47	PTGDS,PARD3B,ATP1A2,RORA,PARD3,PITPNC1
2.345e-02	-3.75	GRIN1 (glutamate ionotropic receptor NMDA type subunit 1)	protein interactions	2902	94	2	19454	49	CAMK2G,FGFR3
2.345e-02	-3.75	QSER1 (glutamine and serine rich 1)	protein interactions	79832	94	2	19454	49	SOX5,NFIA
2.345e-02	-3.75	FOXP4 (forkhead box P4)	protein interactions	116113	94	2	19454	49	SOX5,NFIA
2.345e-02	-3.75	WWC1 (WW and C2 domain containing 1)	protein interactions	23286	94	2	19454	49	ABLIM1,TNIK
2.349e-02	-3.75	positive regulation of synapse maturation	biological process	GO:0090129	9	1	18204	48	NRXN1
2.349e-02	-3.75	negative regulation of actin nucleation	biological process	GO:0051126	9	1	18204	48	CTNNA2
2.349e-02	-3.75	polyamine transmembrane transport	biological process	GO:1902047	9	1	18204	48	ATP13A4
2.349e-02	-3.75	cyclooxygenase pathway	biological process	GO:0019371	9	1	18204	48	PTGDS
2.349e-02	-3.75	negative regulation of striated muscle contraction	biological process	GO:0045988	9	1	18204	48	ATP1A2
2.349e-02	-3.75	hindbrain radial glia guided cell migration	biological process	GO:0021932	9	1	18204	48	CTNNA2
2.349e-02	-3.75	release of sequestered calcium ion into cytosol by sarcoplasmic reticulum	biological process	GO:0014808	9	1	18204	48	RYR3
2.353e-02	-3.75	regulation of purine nucleotide metabolic process	biological process	GO:1900542	90	2	18204	48	ZBTB20,SLC4A4
2.353e-02	-3.75	Villin headpiece domain	gene3d domains	1.10.950.10	8	1	14470	43	ABLIM1
2.354e-02	-3.75	chemical synaptic transmission	biological process	GO:0007268	415	4	18204	48	DTNA,NRXN1,SLC1A3,SLC1A2
2.354e-02	-3.75	anterograde trans-synaptic signaling	biological process	GO:0098916	415	4	18204	48	SLC1A2,DTNA,SLC1A3,NRXN1
2.357e-02	-3.75	Activin_recp	interpro domains	IPR000472	9	1	18521	49	BMPR1B
2.357e-02	-3.75	DNA-bd_RFX	interpro domains	IPR003150	9	1	18521	49	RFX4
2.357e-02	-3.75	Fol_N	interpro domains	IPR003645	9	1	18521	49	SPARCL1
2.357e-02	-3.75	Band3_cytoplasmic_dom	interpro domains	IPR013769	9	1	18521	49	SLC4A4
2.378e-02	-3.74	double-stranded DNA binding	molecular function	GO:0003690	1643	9	18094	47	MEIS2,ZBTB20,RFX4,NPAS3,HIF3A,NFIA,GLIS3,RORA,SOX5
2.391e-02	-3.73	STRIP1 (striatin interacting protein 1)	protein interactions	85369	95	2	19454	49	CAMK2G,TNIK
2.402e-02	-3.73	response to BMP	biological process	GO:0071772	91	2	18204	48	BMPR1B,NFIA
2.402e-02	-3.73	cellular response to BMP stimulus	biological process	GO:0071773	91	2	18204	48	BMPR1B,NFIA
2.402e-02	-3.73	regulation of nucleotide metabolic process	biological process	GO:0006140	91	2	18204	48	SLC4A4,ZBTB20
2.411e-02	-3.73	human chr5p15.1	chromosome location	human chr5p15.1	13	1	26134	49	FBXL7
2.420e-02	-3.72	fibula	COSMIC cancer mutations	fibula	387	4	16828	48	COL5A3,FGFR3,PRODH,NRXN1
2.425e-02	-3.72	superpathway of L-citrulline metabolism	BIOCYC pathways	META_PWY-5004	11	1	902	2	PRODH
2.426e-02	-3.72	actin filament bundle	cellular component	GO:0032432	96	2	19108	48	ABLIM1,SORBS1
2.426e-02	-3.72	sarcoplasm	cellular component	GO:0016528	96	2	19108	48	CAMK2G,RYR3
2.445e-02	-3.71	GS	prosite domains	PS51256	7	1	12186	43	BMPR1B
2.447e-02	-3.71	axon development	biological process	GO:0061564	420	4	18204	48	NRXN1,PARD3,CTNNA2,BMPR1B
2.452e-02	-3.71	RFX_DNA_binding	pfam domains	PF02257	9	1	17795	49	RFX4
2.452e-02	-3.71	Band_3_cyto	pfam domains	PF07565	9	1	17795	49	SLC4A4
2.452e-02	-3.71	Activin_recp	pfam domains	PF01064	9	1	17795	49	BMPR1B
2.452e-02	-3.71	NCOR2 (nuclear receptor corepressor 2)	protein interactions	9612	248	3	19454	49	SOX5,NFIA,TNIK
2.454e-02	-3.71	sequence-specific DNA binding	molecular function	GO:0043565	1652	9	18094	47	GLIS3,NFIA,SOX5,RORA,ZBTB20,MEIS2,HIF3A,NPAS3,RFX4
2.458e-02	-3.71	metal ion transport	biological process	GO:0030001	630	5	18204	48	SLC4A4,ATP1A2,GPM6A,RYR3,SLC1A3
2.474e-02	-3.70	Transmission across Chemical Synapses	REACTOME pathways	R-HSA-112315	217	3	10285	30	CAMK2G,SLC1A3,SLC1A2
2.478e-02	-3.70	MYO1B (myosin IB)	protein interactions	4430	249	3	19454	49	CAMK2G,PARD3,FGFR3
2.479e-02	-3.70	muscle contraction	biological process	GO:0006936	238	3	18204	48	RYR3,ATP1A2,DTNA
2.485e-02	-3.70	response to radiation	biological process	GO:0009314	422	4	18204	48	ATP1A2,SLC1A3,MEIS2,SLC1A2
2.486e-02	-3.69	PLCB3 (phospholipase C beta 3)	protein interactions	5331	97	2	19454	49	PARD3,CAMK2G
2.491e-02	-3.69	TSHZ1 (teashirt zinc finger homeobox 1)	protein interactions	10194	10	1	19454	49	MEIS2
2.491e-02	-3.69	CALB2 (calbindin 2)	protein interactions	794	10	1	19454	49	GPM6A
2.491e-02	-3.69	SLC8A2 (solute carrier family 8 member A2)	protein interactions	6543	10	1	19454	49	GPM6A
2.491e-02	-3.69	Smurf2 (SMAD specific E3 ubiquitin protein ligase 2)	protein interactions	66313	10	1	19454	49	GLIS3
2.491e-02	-3.69	GSG1 (germ cell associated 1)	protein interactions	83445	10	1	19454	49	PITPNC1
2.491e-02	-3.69	Vbp1 (von Hippel-Lindau binding protein 1)	protein interactions	22327	10	1	19454	49	ABLIM1
2.495e-02	-3.69	GS	smart domains	SM00467	7	1	9717	35	BMPR1B
2.510e-02	-3.68	Protein digestion and absorption	KEGG pathways	ko04974	89	2	7161	20	COL5A3,ATP1A2
2.510e-02	-3.68	Protein digestion and absorption	KEGG pathways	hsa04974	89	2	7161	20	ATP1A2,COL5A3
2.534e-02	-3.68	DNAAF2 (dynein axonemal assembly factor 2)	protein interactions	55172	98	2	19454	49	LSAMP,GPM6A
2.539e-02	-3.67	skin-benign_melanocytic_nevus-congenital	COSMIC cancer mutations	skin-benign_melanocytic_nevus-congenital	9	1	16828	48	FGFR3
2.539e-02	-3.67	compound	COSMIC cancer mutations	compound	9	1	16828	48	FGFR3
2.539e-02	-3.67	Bowen_disease	COSMIC cancer mutations	Bowen_disease	9	1	16828	48	FGFR3
2.539e-02	-3.67	epidermal_nevus	COSMIC cancer mutations	epidermal_nevus	9	1	16828	48	FGFR3
2.539e-02	-3.67	ovary-low_malignant_potential_(borderline)_tumour-Brenner_tumour	COSMIC cancer mutations	ovary-low_malignant_potential_(borderline)_tumour-Brenner_tumour	9	1	16828	48	FGFR3
2.539e-02	-3.67	skin-other-seborrhoeic_keratosis	COSMIC cancer mutations	skin-other-seborrhoeic_keratosis	9	1	16828	48	FGFR3
2.539e-02	-3.67	in_situ_epithelial_neoplasm	COSMIC cancer mutations	in_situ_epithelial_neoplasm	9	1	16828	48	FGFR3
2.551e-02	-3.67	mitochondrial transmembrane transport	biological process	GO:1990542	94	2	18204	48	SLC25A18,SFXN5
2.555e-02	-3.67	NCK2 (NCK adaptor protein 2)	protein interactions	8440	252	3	19454	49	SORBS1,TNIK,NHSL1
2.563e-02	-3.66	Salivary secretion	KEGG pathways	ko04970	90	2	7161	20	RYR3,ATP1A2
2.563e-02	-3.66	Salivary secretion	KEGG pathways	hsa04970	90	2	7161	20	RYR3,ATP1A2
2.568e-02	-3.66	polyamine transmembrane transporter activity	molecular function	GO:0015203	10	1	18094	47	ATP13A4
2.568e-02	-3.66	phosphatidylinositol transfer activity	molecular function	GO:0008526	10	1	18094	47	PITPNC1
2.580e-02	-3.66	ATPase-coupled transmembrane transporter activity	molecular function	GO:0042626	96	2	18094	47	ATP13A4,ATP1A2
2.582e-02	-3.66	TNKS (tankyrase)	protein interactions	8658	99	2	19454	49	TNIK,PCDH9
2.594e-02	-3.65	human chr2p13.2	chromosome location	human chr2p13.2	14	1	26134	49	SFXN5
2.594e-02	-3.65	human chr2p16.3	chromosome location	human chr2p16.3	14	1	26134	49	NRXN1
2.595e-02	-3.65	pancreas-other-adenoma	COSMIC cancer mutations	pancreas-other-adenoma	224	3	16828	48	BMPR1B,PCDH9,CTNND2
2.606e-02	-3.65	neuronal action potential propagation	biological process	GO:0019227	10	1	18204	48	ATP1A2
2.606e-02	-3.65	action potential propagation	biological process	GO:0098870	10	1	18204	48	ATP1A2
2.606e-02	-3.65	proline metabolic process	biological process	GO:0006560	10	1	18204	48	PRODH
2.606e-02	-3.65	learned vocalization behavior or vocal learning	biological process	GO:0098598	10	1	18204	48	NRXN1
2.606e-02	-3.65	release of sequestered calcium ion into cytosol by endoplasmic reticulum	biological process	GO:1903514	10	1	18204	48	RYR3
2.606e-02	-3.65	postsynaptic density assembly	biological process	GO:0097107	10	1	18204	48	NRXN1
2.606e-02	-3.65	regulation of mesenchymal stem cell differentiation	biological process	GO:2000739	10	1	18204	48	SOX5
2.606e-02	-3.65	otolith development	biological process	GO:0048840	10	1	18204	48	LRIG1
2.606e-02	-3.65	postsynaptic membrane assembly	biological process	GO:0097104	10	1	18204	48	NRXN1
2.615e-02	-3.64	MIR_motif	interpro domains	IPR016093	10	1	18521	49	RYR3
2.615e-02	-3.64	PAS_fold_3	interpro domains	IPR013655	10	1	18521	49	NPAS3
2.615e-02	-3.64	PTrfase/Anion_transptr	interpro domains	IPR016152	10	1	18521	49	SLC4A4
2.615e-02	-3.64	MIR_dom_sf	interpro domains	IPR036300	10	1	18521	49	RYR3
2.615e-02	-3.64	HCO3_transpt-like_TM_dom	interpro domains	IPR011531	10	1	18521	49	SLC4A4
2.615e-02	-3.64	HCO3_transpt_euk	interpro domains	IPR003020	10	1	18521	49	SLC4A4
2.630e-02	-3.64	ATP4A (ATPase H+/K+ transporting subunit alpha)	protein interactions	495	100	2	19454	49	ATP1A2,GPM6A
2.630e-02	-3.64	APBA1 (amyloid beta precursor protein binding family A member 1)	protein interactions	320	100	2	19454	49	ABLIM1,NRXN1
2.659e-02	-3.63	trans-synaptic signaling	biological process	GO:0099537	431	4	18204	48	SLC1A2,DTNA,NRXN1,SLC1A3
2.679e-02	-3.62	CLEC4A (C-type lectin domain family 4 member A)	protein interactions	50856	101	2	19454	49	CTNNA2,FGFR3
2.698e-02	-3.61	inorganic ion homeostasis	biological process	GO:0098771	433	4	18204	48	RYR3,SLC1A3,ATP13A4,ATP1A2
2.699e-02	-3.61	regulation of synapse organization	biological process	GO:0050807	246	3	18204	48	GPM6A,NRXN1,CTNNA2
2.704e-02	-3.61	nerve development	biological process	GO:0021675	97	2	18204	48	SLC1A3,LRIG1
2.711e-02	-3.61	Ig-like_dom	interpro domains	IPR007110	432	4	18521	49	NTM,LSAMP,FGFR3,LRIG1
2.720e-02	-3.60	HCO3_cotransp	pfam domains	PF00955	10	1	17795	49	SLC4A4
2.720e-02	-3.60	MIR	pfam domains	PF02815	10	1	17795	49	RYR3
2.720e-02	-3.60	PAS_3	pfam domains	PF08447	10	1	17795	49	NPAS3
2.724e-02	-3.60	LIPOCALIN	prints domains	PR00179	8	1	5227	18	PTGDS
2.724e-02	-3.60	serous_carcinoma	COSMIC cancer mutations	serous_carcinoma	10987	38	16828	48	LRIG1,ATP1A2,PARD3,BMPR1B,PAMR1,PTGDS,NHSL1,CAMK2G,COL5A3,FBXL7,GPC5,ZNRF3,CTNND2,MEIS2,SLC4A4,SOX5,FGFR3,RORA,NTM,SFXN5,ATP13A4,SORBS1,PCDH9,NRXN1,ZBTB20,MSI2,LSAMP,CDH20,GLIS3,DTNA,ACSS1,AHCYL2,RYR3,SLC1A2,PARD3B,NPAS3,SLC1A3,TNIK
2.737e-02	-3.60	AQP5 (aquaporin 5)	protein interactions	362	11	1	19454	49	ATP1A2
2.737e-02	-3.60	GAL3ST1 (galactose-3-O-sulfotransferase 1)	protein interactions	9514	11	1	19454	49	LRIG1
2.737e-02	-3.60	PTGDR (prostaglandin D2 receptor)	protein interactions	5729	11	1	19454	49	PTGDS
2.737e-02	-3.60	CCDC17 (coiled-coil domain containing 17)	protein interactions	149483	11	1	19454	49	FGFR3
2.737e-02	-3.60	SYTL1 (synaptotagmin like 1)	protein interactions	84958	11	1	19454	49	NRXN1
2.737e-02	-3.60	Cobll1 (Cobl-like 1)	protein interactions	319876	11	1	19454	49	ABLIM1
2.737e-02	-3.60	Gtf2e2 (general transcription factor II E, polypeptide 2 (beta subunit))	protein interactions	68153	11	1	19454	49	NHSL1
2.737e-02	-3.60	SYN3 (synapsin III)	protein interactions	8224	11	1	19454	49	GPM6A
2.742e-02	-3.60	MARK2 (microtubule affinity regulating kinase 2)	protein interactions	2011	259	3	19454	49	PARD3,DTNA,PARD3B
2.760e-02	-3.59	Methionine degradation	KEGG pathways	hsa_M00035	10	1	7161	20	AHCYL2
2.760e-02	-3.59	Methionine degradation	KEGG pathways	M00035	10	1	7161	20	AHCYL2
2.777e-02	-3.58	human chr8q12.3	chromosome location	human chr8q12.3	15	1	26134	49	NKAIN3
2.778e-02	-3.58	RAB6B (RAB6B, member RAS oncogene family)	protein interactions	51560	103	2	19454	49	BMPR1B,GPM6A
2.789e-02	-3.58	HP	prosite domains	PS51089	8	1	12186	43	ABLIM1
2.808e-02	-3.57	bone morphogenesis	biological process	GO:0060349	99	2	18204	48	FGFR3,BMPR1B
2.817e-02	-3.57	intradermal	COSMIC cancer mutations	intradermal	10	1	16828	48	FGFR3
2.817e-02	-3.57	cervix-in_situ_neoplasm-cervical_intraepithelial_neoplasia_Grade_III	COSMIC cancer mutations	cervix-in_situ_neoplasm-cervical_intraepithelial_neoplasia_Grade_III	10	1	16828	48	FGFR3
2.817e-02	-3.57	lung-carcinoma-pleomorphic_carcinoma	COSMIC cancer mutations	lung-carcinoma-pleomorphic_carcinoma	10	1	16828	48	FGFR3
2.817e-02	-3.57	renal_cell_carcinoma_unclassified	COSMIC cancer mutations	renal_cell_carcinoma_unclassified	10	1	16828	48	FGFR3
2.817e-02	-3.57	kidney-carcinoma-renal_cell_carcinoma_unclassified	COSMIC cancer mutations	kidney-carcinoma-renal_cell_carcinoma_unclassified	10	1	16828	48	FGFR3
2.817e-02	-3.57	cervical_intraepithelial_neoplasia_Grade_III	COSMIC cancer mutations	cervical_intraepithelial_neoplasia_Grade_III	10	1	16828	48	FGFR3
2.821e-02	-3.57	acetylcholine receptor binding	molecular function	GO:0033130	11	1	18094	47	NRXN1
2.821e-02	-3.57	sulfur amino acid transmembrane transporter activity	molecular function	GO:0000099	11	1	18094	47	SLC1A2
2.833e-02	-3.56	Pancreatic secretion	KEGG pathways	ko04972	95	2	7161	20	ATP1A2,SLC4A4
2.833e-02	-3.56	Pancreatic secretion	KEGG pathways	hsa04972	95	2	7161	20	ATP1A2,SLC4A4
2.844e-02	-3.56	skin-hand-carcinoma-squamous_cell_carcinoma	COSMIC cancer mutations	skin-hand-carcinoma-squamous_cell_carcinoma	407	4	16828	48	COL5A3,SLC4A4,FGFR3,HIF3A
2.845e-02	-3.56	cell development	biological process	GO:0048468	2236	11	18204	48	CTNND2,CTNNA2,NRXN1,MSI2,TNIK,BMPR1B,NTM,RORA,PARD3,GPM6A,SLC1A3
2.846e-02	-3.56	VHP	smart domains	SM00153	8	1	9717	35	ABLIM1
2.849e-02	-3.56	protein binding	molecular function	GO:0005515	13983	42	18094	47	GPC5,CTNNA2,NRXN1,SLC4A4,PARD3B,ABLIM1,ATP1A2,RYR3,RFX4,PTGDS,PARD3,GLIS3,SFXN5,NTM,FGFR3,SOX5,BMPR1B,COL5A3,ZNRF3,CDH20,TNIK,LRIG1,NFIA,PITPNC1,GPM6A,SLC1A2,MEIS2,ACSS1,LSAMP,HIF3A,CAMK2G,SLC25A18,MSI2,DTNA,RORA,SPARCL1,SLC1A3,SORBS1,AHCYL2,FBXL7,CTNND2,NPAS3
2.863e-02	-3.55	polyamine transport	biological process	GO:0015846	11	1	18204	48	ATP13A4
2.863e-02	-3.55	lactone metabolic process	biological process	GO:1901334	11	1	18204	48	ATP1A2
2.863e-02	-3.55	cellular response to caffeine	biological process	GO:0071313	11	1	18204	48	RYR3
2.863e-02	-3.55	establishment or maintenance of transmembrane electrochemical gradient	biological process	GO:0010248	11	1	18204	48	ATP1A2
2.863e-02	-3.55	antral ovarian follicle growth	biological process	GO:0001547	11	1	18204	48	BMPR1B
2.863e-02	-3.55	L-ascorbic acid metabolic process	biological process	GO:0019852	11	1	18204	48	ATP1A2
2.871e-02	-3.55	regulation of synapse structure or activity	biological process	GO:0050803	252	3	18204	48	NRXN1,GPM6A,CTNNA2
2.873e-02	-3.55	Fib_collagen_C	interpro domains	IPR000885	11	1	18521	49	COL5A3
2.878e-02	-3.55	ANP32E (acidic nuclear phosphoprotein 32 family member E)	protein interactions	81611	105	2	19454	49	PARD3,AHCYL2
2.880e-02	-3.55	Organic anion transporters	REACTOME pathways	R-HSA-428643	10	1	10285	30	SLC25A18
2.880e-02	-3.55	Signaling by FGFR3 fusions in cancer	REACTOME pathways	R-HSA-8853334	10	1	10285	30	FGFR3
2.889e-02	-3.54	Circadian entrainment	KEGG pathways	hsa04713	96	2	7161	20	CAMK2G,RYR3
2.889e-02	-3.54	Circadian entrainment	KEGG pathways	ko04713	96	2	7161	20	RYR3,CAMK2G
2.897e-02	-3.54	endoplasmic reticulum	cellular component	GO:0005783	2051	10	19108	48	FGFR3,PTGDS,RYR3,NRXN1,SPARCL1,CAMK2G,ATP1A2,COL5A3,ATP13A4,AHCYL2
2.914e-02	-3.54	regulation of glucose metabolic process	biological process	GO:0010906	101	2	18204	48	SORBS1,RORA
2.927e-02	-3.53	Post-translational modification: synthesis of GPI-anchored proteins	REACTOME pathways	R-HSA-163125	92	2	10285	30	NTM,LSAMP
2.933e-02	-3.53	Helical hairpin bin	gene3d domains	1.10.287.570	10	1	14470	43	SLC4A4
2.974e-02	-3.52	sodium:potassium-exchanging ATPase complex	cellular component	GO:0005890	12	1	19108	48	ATP1A2
2.974e-02	-3.52	banded collagen fibril	cellular component	GO:0098643	12	1	19108	48	COL5A3
2.974e-02	-3.52	fibrillar collagen trimer	cellular component	GO:0005583	12	1	19108	48	COL5A3
2.982e-02	-3.51	IL15 (interleukin 15)	protein interactions	3600	12	1	19454	49	LRIG1
2.982e-02	-3.51	FAM222A (family with sequence similarity 222 member A)	protein interactions	84915	12	1	19454	49	MEIS2
2.982e-02	-3.51	LGR5 (leucine rich repeat containing G protein-coupled receptor 5)	protein interactions	8549	12	1	19454	49	ZNRF3
2.982e-02	-3.51	CA4 (carbonic anhydrase 4)	protein interactions	762	12	1	19454	49	SLC4A4
2.982e-02	-3.51	Pard6b (par-6 family cell polarity regulator beta)	protein interactions	58220	12	1	19454	49	PARD3
2.982e-02	-3.51	ART4 (ADP-ribosyltransferase 4 (inactive) (Dombrock blood group))	protein interactions	420	12	1	19454	49	GPM6A
2.982e-02	-3.51	LMP-1 (latent membrane protein LMP-1)	protein interactions	3783750	12	1	19454	49	TNIK
2.982e-02	-3.51	BAMBI (BMP and activin membrane bound inhibitor)	protein interactions	25805	12	1	19454	49	BMPR1B
2.988e-02	-3.51	COLFI	pfam domains	PF01410	11	1	17795	49	COL5A3
2.988e-02	-3.51	LRRCT	pfam domains	PF01463	11	1	17795	49	LRIG1
2.988e-02	-3.51	PAS_11	pfam domains	PF14598	11	1	17795	49	HIF3A
3.031e-02	-3.50	kidney-other-neoplasm	COSMIC cancer mutations	kidney-other-neoplasm	10653	37	16828	48	NHSL1,PAMR1,PARD3,ATP1A2,LRIG1,SLC25A18,CTNND2,GPC5,FBXL7,COL5A3,CAMK2G,MEIS2,NKAIN3,RORA,GPM6A,FGFR3,RFX4,SOX5,NRXN1,PCDH9,SORBS1,PRODH,SFXN5,ATP13A4,SPARCL1,CDH20,LSAMP,ZBTB20,AHCYL2,ACSS1,ABLIM1,DTNA,TNIK,SLC1A3,NPAS3,SLC1A2,RYR3
3.031e-02	-3.50	FKBP1A (FKBP prolyl isomerase 1A)	protein interactions	2280	108	2	19454	49	MSI2,RYR3
3.031e-02	-3.50	EN1 (engrailed homeobox 1)	protein interactions	2019	108	2	19454	49	AHCYL2,NFIA
3.031e-02	-3.50	CAMKV (CaM kinase like vesicle associated)	protein interactions	79012	108	2	19454	49	AHCYL2,GPM6A
3.033e-02	-3.50	skin-arm-malignant_melanoma	COSMIC cancer mutations	skin-arm-malignant_melanoma	1308	8	16828	48	SORBS1,SLC4A4,ATP1A2,NTM,PARD3B,COL5A3,ZBTB20,NPAS3
3.034e-02	-3.50	Ethanol Degradation	SMPDB pathways	SMP0000449	7	1	1369	6	ACSS1
3.054e-02	-3.49	oesophagus-carcinoma-adenocarcinoma	COSMIC cancer mutations	oesophagus-carcinoma-adenocarcinoma	13112	43	16828	48	RFX4,SOX5,GPM6A,NKAIN3,MEIS2,SLC4A4,CAMK2G,ZNRF3,CTNND2,SLC25A18,ATP1A2,LRIG1,BMPR1B,PTGDS,RYR3,SLC1A2,PARD3B,ACSS1,AHCYL2,LSAMP,SPARCL1,SFXN5,PRODH,SORBS1,FGFR3,HIF3A,RORA,NTM,COL5A3,FBXL7,GPC5,PARD3,PAMR1,NHSL1,NPAS3,SLC1A3,TNIK,ZBTB20,CDH20,GLIS3,ATP13A4,NRXN1,PCDH9
3.076e-02	-3.48	EF-hand-dom_pair	interpro domains	IPR011992	258	3	18521	49	RYR3,SPARCL1,DTNA
3.094e-02	-3.48	skin-neck-carcinoma-basal_cell_carcinoma	COSMIC cancer mutations	skin-neck-carcinoma-basal_cell_carcinoma	11	1	16828	48	FGFR3
3.094e-02	-3.48	pleomorphic_carcinoma	COSMIC cancer mutations	pleomorphic_carcinoma	11	1	16828	48	FGFR3
3.094e-02	-3.48	seborrhoeic_keratosis	COSMIC cancer mutations	seborrhoeic_keratosis	11	1	16828	48	FGFR3
3.094e-02	-3.48	prostate-hyperplasia	COSMIC cancer mutations	prostate-hyperplasia	11	1	16828	48	FGFR3
3.094e-02	-3.48	congenital	COSMIC cancer mutations	congenital	11	1	16828	48	FGFR3
3.094e-02	-3.48	kidney-other-oncocytoma	COSMIC cancer mutations	kidney-other-oncocytoma	11	1	16828	48	FGFR3
3.094e-02	-3.48	oncocytoma	COSMIC cancer mutations	oncocytoma	11	1	16828	48	FGFR3
3.094e-02	-3.48	skin-scalp-carcinoma-basal_cell_carcinoma	COSMIC cancer mutations	skin-scalp-carcinoma-basal_cell_carcinoma	11	1	16828	48	FGFR3
3.100e-02	-3.47	YWHAG (tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein gamma)	protein interactions	7532	1211	7	19454	49	PITPNC1,PARD3,ABLIM1,NHSL1,PARD3B,SORBS1,CAMK2G
3.120e-02	-3.47	mammalian oogenesis stage	biological process	GO:0022605	12	1	18204	48	BMPR1B
3.120e-02	-3.47	4-hydroxyproline metabolic process	biological process	GO:0019471	12	1	18204	48	PRODH
3.120e-02	-3.47	sulfur amino acid transport	biological process	GO:0000101	12	1	18204	48	SLC1A2
3.120e-02	-3.47	positive regulation of extrinsic apoptotic signaling pathway via death domain receptors	biological process	GO:1902043	12	1	18204	48	BMPR1B
3.121e-02	-3.47	NR3C1 (nuclear receptor subfamily 3 group C member 1)	protein interactions	2908	950	6	19454	49	NFIA,CTNND2,ZBTB20,ATP13A4,SLC1A3,CAMK2G
3.130e-02	-3.46	Lipocalin_CS	interpro domains	IPR022272	12	1	18521	49	PTGDS
3.130e-02	-3.46	Lipocalin	interpro domains	IPR002345	12	1	18521	49	PTGDS
3.130e-02	-3.46	TGFB_receptor	interpro domains	IPR000333	12	1	18521	49	BMPR1B
3.130e-02	-3.46	MAD_homology1_Dwarfin-type	interpro domains	IPR003619	12	1	18521	49	NFIA
3.132e-02	-3.46	RFX_DBD	prosite domains	PS51526	9	1	12186	43	RFX4
3.135e-02	-3.46	LZTR1 (leucine zipper like post translational regulator 1)	protein interactions	8216	110	2	19454	49	BMPR1B,PARD3B
3.139e-02	-3.46	cell-cell adhesion via plasma-membrane adhesion molecules	biological process	GO:0098742	261	3	18204	48	SPARCL1,PCDH9,CDH20
3.139e-02	-3.46	calcium ion binding	molecular function	GO:0005509	683	5	18094	47	SPARCL1,PAMR1,NRXN1,PCDH9,RYR3
3.151e-02	-3.46	steroid binding	molecular function	GO:0005496	107	2	18094	47	RORA,ATP1A2
3.185e-02	-3.45	soft_tissue-striated_muscle-rhabdomyosarcoma-embryonal	COSMIC cancer mutations	soft_tissue-striated_muscle-rhabdomyosarcoma-embryonal	2659	13	16828	48	RYR3,FGFR3,PARD3B,NPAS3,RORA,CAMK2G,COL5A3,ZNRF3,GLIS3,CTNND2,NFIA,SPARCL1,SORBS1
3.185e-02	-3.45	embryonal	COSMIC cancer mutations	embryonal	2659	13	16828	48	CAMK2G,COL5A3,GLIS3,ZNRF3,NFIA,CTNND2,SPARCL1,SORBS1,RYR3,NPAS3,PARD3B,FGFR3,RORA
3.197e-02	-3.44	FOLN	smart domains	SM00274	9	1	9717	35	SPARCL1
3.226e-02	-3.43	JAM2 (junctional adhesion molecule 2)	protein interactions	58494	13	1	19454	49	PARD3
3.226e-02	-3.43	RAB3C (RAB3C, member RAS oncogene family)	protein interactions	115827	13	1	19454	49	GPM6A
3.226e-02	-3.43	PCDHA2 (protocadherin alpha 2)	protein interactions	56146	13	1	19454	49	NFIA
3.226e-02	-3.43	MYO16 (myosin XVI)	protein interactions	23026	13	1	19454	49	NRXN1
3.226e-02	-3.43	TBCC (tubulin folding cofactor C)	protein interactions	6903	13	1	19454	49	NTM
3.226e-02	-3.43	CAPN11 (calpain 11)	protein interactions	11131	13	1	19454	49	PRODH
3.226e-02	-3.43	MAB21L1 (mab-21 like 1)	protein interactions	4081	13	1	19454	49	MEIS2
3.226e-02	-3.43	NPR2 (natriuretic peptide receptor 2)	protein interactions	4882	13	1	19454	49	CAMK2G
3.226e-02	-3.43	PLPPR4 (phospholipid phosphatase related 4)	protein interactions	9890	13	1	19454	49	ZNRF3
3.241e-02	-3.43	TBR1 (T-box brain transcription factor 1)	protein interactions	10716	112	2	19454	49	SOX5,NFIA
3.246e-02	-3.43	synaptic signaling	biological process	GO:0099536	459	4	18204	48	DTNA,NRXN1,SLC1A3,SLC1A2
3.256e-02	-3.42	MH1	pfam domains	PF03165	12	1	17795	49	NFIA
3.262e-02	-3.42	regulation of canonical Wnt signaling pathway	biological process	GO:0060828	265	3	18204	48	CTNND2,ZNRF3,GPC5
3.273e-02	-3.42	rhabdomyosarcoma	COSMIC cancer mutations	rhabdomyosarcoma	4150	18	16828	48	RYR3,NPAS3,FGFR3,PARD3B,SLC1A3,RORA,CAMK2G,COL5A3,GLIS3,ZNRF3,CDH20,CTNND2,NFIA,SPARCL1,PARD3,SORBS1,PAMR1,NHSL1
3.294e-02	-3.41	GFI1B (growth factor independent 1B transcriptional repressor)	protein interactions	8328	113	2	19454	49	DTNA,ZNRF3
3.323e-02	-3.40	human chr18q21.33	chromosome location	human chr18q21.33	18	1	26134	49	CDH20
3.326e-02	-3.40	potassium ion binding	molecular function	GO:0030955	13	1	18094	47	ATP1A2
3.326e-02	-3.40	monoatomic cation:bicarbonate symporter activity	molecular function	GO:0140410	13	1	18094	47	SLC4A4
3.326e-02	-3.40	transforming growth factor beta receptor activity	molecular function	GO:0005024	13	1	18094	47	BMPR1B
3.330e-02	-3.40	plasma membrane raft	cellular component	GO:0044853	114	2	19108	48	SORBS1,ATP1A2
3.347e-02	-3.40	ORF3b (ORF3b protein)	protein interactions	1489670	114	2	19454	49	ZBTB20,PCDH9
3.351e-02	-3.40	postsynapse organization	biological process	GO:0099173	109	2	18204	48	CTNND2,NRXN1
3.371e-02	-3.39	skin-face-carcinoma-basal_cell_carcinoma	COSMIC cancer mutations	skin-face-carcinoma-basal_cell_carcinoma	12	1	16828	48	FGFR3
3.371e-02	-3.39	skin-benign_melanocytic_nevus	COSMIC cancer mutations	skin-benign_melanocytic_nevus	12	1	16828	48	FGFR3
3.371e-02	-3.39	cervix-carcinoma-mixed_adenosquamous_carcinoma	COSMIC cancer mutations	cervix-carcinoma-mixed_adenosquamous_carcinoma	12	1	16828	48	FGFR3
3.373e-02	-3.39	Cadherin_CS	interpro domains	IPR020894	109	2	18521	49	CDH20,PCDH9
3.375e-02	-3.39	cerebellar Purkinje cell differentiation	biological process	GO:0021702	13	1	18204	48	RORA
3.375e-02	-3.39	regulation of respiratory gaseous exchange by nervous system process	biological process	GO:0002087	13	1	18204	48	ATP1A2
3.375e-02	-3.39	glial cell fate commitment	biological process	GO:0021781	13	1	18204	48	NFIA
3.375e-02	-3.39	negative regulation of cytosolic calcium ion concentration	biological process	GO:0051481	13	1	18204	48	ATP1A2
3.375e-02	-3.39	T-helper 17 cell differentiation	biological process	GO:0072539	13	1	18204	48	RORA
3.375e-02	-3.39	prepulse inhibition	biological process	GO:0060134	13	1	18204	48	CTNNA2
3.375e-02	-3.39	postsynaptic specialization assembly	biological process	GO:0098698	13	1	18204	48	NRXN1
3.376e-02	-3.39	DNA-binding transcription activator activity, RNA polymerase II-specific	molecular function	GO:0001228	472	4	18094	47	RFX4,GLIS3,MEIS2,NFIA
3.383e-02	-3.39	kidney-carcinoma-chromophobe_renal_cell_carcinoma	COSMIC cancer mutations	kidney-carcinoma-chromophobe_renal_cell_carcinoma	430	4	16828	48	TNIK,CAMK2G,FGFR3,BMPR1B
3.383e-02	-3.39	chromophobe_renal_cell_carcinoma	COSMIC cancer mutations	chromophobe_renal_cell_carcinoma	430	4	16828	48	TNIK,CAMK2G,BMPR1B,FGFR3
3.394e-02	-3.38	HCO3TRNSPORT	prints domains	PR01231	10	1	5227	18	SLC4A4
3.401e-02	-3.38	CAV1 (caveolin 1)	protein interactions	857	719	5	19454	49	AHCYL2,PARD3,DTNA,TNIK,SLC1A3
3.401e-02	-3.38	CDH2 (cadherin 2)	protein interactions	1000	115	2	19454	49	PARD3,CTNND2
3.432e-02	-3.37	small_intestine	COSMIC cancer mutations	small_intestine	250	3	16828	48	ZNRF3,TNIK,FGFR3
3.446e-02	-3.37	Defective EXT1 causes exostoses 1, TRPS2 and CHDS	REACTOME pathways	R-HSA-3656253	12	1	10285	30	GPC5
3.446e-02	-3.37	Regulation of gene expression by Hypoxia-inducible Factor	REACTOME pathways	R-HSA-1234158	12	1	10285	30	HIF3A
3.446e-02	-3.37	Defective EXT2 causes exostoses 2	REACTOME pathways	R-HSA-3656237	12	1	10285	30	GPC5
3.446e-02	-3.37	Signaling by activated point mutants of FGFR3	REACTOME pathways	R-HSA-1839130	12	1	10285	30	FGFR3
3.446e-02	-3.37	Ethanol oxidation	REACTOME pathways	R-HSA-71384	12	1	10285	30	ACSS1
3.446e-02	-3.37	FGFR3 mutant receptor activation	REACTOME pathways	R-HSA-2033514	12	1	10285	30	FGFR3
3.452e-02	-3.37	carboxylic acid biosynthetic process	biological process	GO:0046394	271	3	18204	48	ACSS1,SLC1A3,PTGDS
3.462e-02	-3.36	Bile Acid Indirect Signalling Pathway	SMPDB pathways	SMP0086851	8	1	1369	6	FGFR3
3.465e-02	-3.36	Dppa3 (developmental pluripotency-associated 3)	protein interactions	73708	284	3	19454	49	ATP1A2,CAMK2G,MSI2
3.470e-02	-3.36	PLXNA4 (plexin A4)	protein interactions	91584	14	1	19454	49	GPM6A
3.470e-02	-3.36	SLC1A2 (solute carrier family 1 member 2)	protein interactions	6506	14	1	19454	49	SLC1A2
3.470e-02	-3.36	KRTAP22-1 (keratin associated protein 22-1)	protein interactions	337979	14	1	19454	49	MEIS2
3.470e-02	-3.36	RHEBL1 (RHEB like 1)	protein interactions	121268	14	1	19454	49	BMPR1B
3.470e-02	-3.36	SYT5 (synaptotagmin 5)	protein interactions	6861	14	1	19454	49	NRXN1
3.470e-02	-3.36	FGF7 (fibroblast growth factor 7)	protein interactions	2252	14	1	19454	49	FGFR3
3.470e-02	-3.36	CHAT (choline O-acetyltransferase)	protein interactions	1103	14	1	19454	49	CAMK2G
3.470e-02	-3.36	VSX2 (visual system homeobox 2)	protein interactions	338917	14	1	19454	49	AHCYL2
3.470e-02	-3.36	TPSAB1 (tryptase alpha/beta 1)	protein interactions	7177	14	1	19454	49	CAMK2G
3.470e-02	-3.36	Nedd4 (neural precursor cell expressed, developmentally down-regulated 4)	protein interactions	17999	14	1	19454	49	GLIS3
3.470e-02	-3.36	RSPO1 (R-spondin 1)	protein interactions	284654	14	1	19454	49	ZNRF3
3.474e-02	-3.36	MIR	prosite domains	PS50919	10	1	12186	43	RYR3
3.479e-02	-3.36	phosphatidylinositol binding	molecular function	GO:0035091	276	3	18094	47	PARD3,PARD3B,PITPNC1
3.504e-02	-3.35	human chr11q25	chromosome location	human chr11q25	19	1	26134	49	NTM
3.504e-02	-3.35	human chr6q24.1	chromosome location	human chr6q24.1	19	1	26134	49	NHSL1
3.504e-02	-3.35	human chr5p15.2	chromosome location	human chr5p15.2	19	1	26134	49	CTNND2
3.510e-02	-3.35	-	gene3d domains	3.10.450.50	12	1	14470	43	CAMK2G
3.510e-02	-3.35	Alpha-catenin/vinculin-like	gene3d domains	1.20.120.230	12	1	14470	43	CTNNA2
3.510e-02	-3.35	SYT6 (synaptotagmin 6)	protein interactions	148281	117	2	19454	49	AHCYL2,NRXN1
3.512e-02	-3.35	DNA-binding transcription activator activity	molecular function	GO:0001216	478	4	18094	47	GLIS3,NFIA,MEIS2,RFX4
3.514e-02	-3.35	bile_duct	COSMIC cancer mutations	bile_duct	15095	47	16828	48	NTM,HIF3A,RORA,FGFR3,GPC5,FBXL7,COL5A3,NHSL1,PAMR1,PARD3,TNIK,SLC1A3,NPAS3,ABLIM1,DTNA,GLIS3,CDH20,MSI2,ZBTB20,PCDH9,NRXN1,ATP13A4,GPM6A,RFX4,SOX5,SLC4A4,MEIS2,SLC25A18,CTNND2,ZNRF3,CAMK2G,PTGDS,BMPR1B,ATP1A2,LRIG1,PARD3B,SLC1A2,RYR3,AHCYL2,ACSS1,NFIA,LSAMP,PITPNC1,SORBS1,PRODH,SFXN5,SPARCL1
3.514e-02	-3.35	biliary_tract-bile_duct-carcinoma-adenocarcinoma	COSMIC cancer mutations	biliary_tract-bile_duct-carcinoma-adenocarcinoma	15095	47	16828	48	AHCYL2,ACSS1,PARD3B,SLC1A2,RYR3,SORBS1,PRODH,SFXN5,SPARCL1,NFIA,PITPNC1,LSAMP,SLC4A4,MEIS2,GPM6A,SOX5,RFX4,PTGDS,BMPR1B,LRIG1,ATP1A2,SLC25A18,CTNND2,ZNRF3,CAMK2G,ABLIM1,DTNA,TNIK,SLC1A3,NPAS3,PCDH9,NRXN1,ATP13A4,GLIS3,CDH20,MSI2,ZBTB20,NTM,RORA,HIF3A,FGFR3,NHSL1,PAMR1,PARD3,GPC5,FBXL7,COL5A3
3.544e-02	-3.34	HLH_DNA-bd_sf	interpro domains	IPR036638	112	2	18521	49	HIF3A,NPAS3
3.544e-02	-3.34	bHLH_dom	interpro domains	IPR011598	112	2	18521	49	HIF3A,NPAS3
3.546e-02	-3.34	MIR	smart domains	SM00472	10	1	9717	35	RYR3
3.549e-02	-3.34	organic acid biosynthetic process	biological process	GO:0016053	274	3	18204	48	PTGDS,ACSS1,SLC1A3
3.560e-02	-3.34	Bone Morphogenic Protein (BMP) Signalling and Regulation	WikiPathways	WP1425	12	1	5310	16	BMPR1B
3.560e-02	-3.34	MFAP5-mediated ovarian cancer cell motility and invasiveness	WikiPathways	WP3301	12	1	5310	16	RYR3
3.565e-02	-3.33	PLCD3 (phospholipase C delta 3)	protein interactions	113026	118	2	19454	49	TNIK,AHCYL2
3.567e-02	-3.33	OCLN (occludin)	protein interactions	100506658	495	4	19454	49	ABLIM1,TNIK,DTNA,PARD3
3.579e-02	-3.33	dendrite development	biological process	GO:0016358	113	2	18204	48	CTNNA2,CTNND2
3.589e-02	-3.33	VASP (vasodilator stimulated phosphoprotein)	protein interactions	7408	288	3	19454	49	NHSL1,SORBS1,PARD3
3.609e-02	-3.32	stomach-carcinoma	COSMIC cancer mutations	stomach-carcinoma	439	4	16828	48	BMPR1B,FGFR3,CAMK2G,TNIK
3.611e-02	-3.32	central_nervous_system-cerebellum-glioma-astrocytoma_Grade_I	COSMIC cancer mutations	central_nervous_system-cerebellum-glioma-astrocytoma_Grade_I	105	2	16828	48	PARD3,GPC5
3.615e-02	-3.32	telencephalon development	biological process	GO:0021537	276	3	18204	48	RFX4,ATP1A2,SLC1A2
3.615e-02	-3.32	learning or memory	biological process	GO:0007611	276	3	18204	48	ATP1A2,NRXN1,MEIS2
3.625e-02	-3.32	membrane raft	cellular component	GO:0045121	290	3	19108	48	SLC1A2,SORBS1,ATP1A2
3.630e-02	-3.32	acetyl-CoA biosynthetic process	biological process	GO:0006085	14	1	18204	48	ACSS1
3.630e-02	-3.32	positive regulation of myoblast proliferation	biological process	GO:2000288	14	1	18204	48	MEIS2
3.630e-02	-3.32	negative regulation of sodium ion transmembrane transporter activity	biological process	GO:2000650	14	1	18204	48	ATP1A2
3.630e-02	-3.32	glutathione biosynthetic process	biological process	GO:0006750	14	1	18204	48	SLC1A2
3.630e-02	-3.32	relaxation of cardiac muscle	biological process	GO:0055119	14	1	18204	48	ATP1A2
3.630e-02	-3.32	regulation of skeletal muscle adaptation	biological process	GO:0014733	14	1	18204	48	CAMK2G
3.630e-02	-3.32	cellular response to purine-containing compound	biological process	GO:0071415	14	1	18204	48	RYR3
3.637e-02	-3.31	regulation of circadian rhythm	biological process	GO:0042752	114	2	18204	48	RORA,PTGDS
3.638e-02	-3.31	extremity	COSMIC cancer mutations	extremity	1876	10	16828	48	PCDH9,ACSS1,ATP13A4,PARD3,CDH20,PITPNC1,RYR3,FBXL7,COL5A3,FGFR3
3.642e-02	-3.31	Neurexin-like	interpro domains	IPR003585	14	1	18521	49	NRXN1
3.647e-02	-3.31	skin-back-carcinoma-basal_cell_carcinoma	COSMIC cancer mutations	skin-back-carcinoma-basal_cell_carcinoma	13	1	16828	48	FGFR3
3.647e-02	-3.31	endometrium-ovary-endometriosis	COSMIC cancer mutations	endometrium-ovary-endometriosis	13	1	16828	48	FGFR3
3.647e-02	-3.31	cervix-carcinoma-adenocarcinoma	COSMIC cancer mutations	cervix-carcinoma-adenocarcinoma	13	1	16828	48	FGFR3
3.647e-02	-3.31	Brenner_tumour	COSMIC cancer mutations	Brenner_tumour	13	1	16828	48	FGFR3
3.660e-02	-3.31	Cadherin-like_dom	interpro domains	IPR002126	114	2	18521	49	CDH20,PCDH9
3.675e-02	-3.30	superficial_spreading	COSMIC cancer mutations	superficial_spreading	1110	7	16828	48	COL5A3,FGFR3,CTNND2,NTM,SLC4A4,ATP13A4,SORBS1
3.676e-02	-3.30	HOXB9 (homeobox B9)	protein interactions	3219	120	2	19454	49	NFIA,AHCYL2
3.680e-02	-3.30	Neural Crest Differentiation	WikiPathways	WP2064	102	2	5310	16	FGFR3,SOX5
3.688e-02	-3.30	membrane microdomain	cellular component	GO:0098857	292	3	19108	48	SLC1A2,SORBS1,ATP1A2
3.695e-02	-3.30	fatty acid biosynthetic process	biological process	GO:0006633	115	2	18204	48	PTGDS,ACSS1
3.704e-02	-3.30	axolemma	cellular component	GO:0030673	15	1	19108	48	SLC1A2
3.710e-02	-3.29	calcium channel activity	molecular function	GO:0005262	117	2	18094	47	RYR3,GPM6A
3.714e-02	-3.29	FGF9 (fibroblast growth factor 9)	protein interactions	2254	15	1	19454	49	FGFR3
3.714e-02	-3.29	IGSF1 (immunoglobulin superfamily member 1)	protein interactions	3547	15	1	19454	49	BMPR1B
3.728e-02	-3.29	FGFR3 ligand binding and activation	REACTOME pathways	R-HSA-190239	13	1	10285	30	FGFR3
3.728e-02	-3.29	FGFR3c ligand binding and activation	REACTOME pathways	R-HSA-190372	13	1	10285	30	FGFR3
3.728e-02	-3.29	Phospholipase C-mediated cascade; FGFR3	REACTOME pathways	R-HSA-5654227	13	1	10285	30	FGFR3
3.731e-02	-3.29	breast-carcinoma-ductolobular_carcinoma	COSMIC cancer mutations	breast-carcinoma-ductolobular_carcinoma	1619	9	16828	48	DTNA,PRODH,ABLIM1,SORBS1,FGFR3,PARD3B,CDH20,RORA,CTNND2
3.731e-02	-3.29	ductolobular_carcinoma	COSMIC cancer mutations	ductolobular_carcinoma	1619	9	16828	48	ABLIM1,PRODH,SORBS1,DTNA,CDH20,CTNND2,RORA,PARD3B,FGFR3
3.738e-02	-3.29	bone-humerus-Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour	COSMIC cancer mutations	bone-humerus-Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour	107	2	16828	48	PARD3B,HIF3A
3.776e-02	-3.28	Prot_kinase_dom	interpro domains	IPR000719	480	4	18521	49	FGFR3,TNIK,BMPR1B,CAMK2G
3.778e-02	-3.28	Cadherin-like_sf	interpro domains	IPR015919	116	2	18521	49	PCDH9,CDH20
3.779e-02	-3.28	KCNE3 (potassium voltage-gated channel subfamily E regulatory subunit 3)	protein interactions	10008	294	3	19454	49	TNIK,PCDH9,ZNRF3
3.783e-02	-3.27	central_nervous_system-brain-primitive_neuroectodermal_tumour-medulloblastoma-large_cell	COSMIC cancer mutations	central_nervous_system-brain-primitive_neuroectodermal_tumour-medulloblastoma-large_cell	1117	7	16828	48	CDH20,GPC5,RYR3,SOX5,SLC1A2,PARD3,ATP13A4
3.788e-02	-3.27	BRK1 (BRICK1 subunit of SCAR/WAVE actin nucleating complex)	protein interactions	55845	122	2	19454	49	NHSL1,DTNA
3.788e-02	-3.27	SLMAP (sarcolemma associated protein)	protein interactions	7871	122	2	19454	49	TNIK,CAMK2G
3.811e-02	-3.27	Cadherin	pfam domains	PF00028	112	2	17795	49	PCDH9,CDH20
3.815e-02	-3.27	NC1_FIB	prosite domains	PS51461	11	1	12186	43	COL5A3
3.815e-02	-3.27	LIPOCALIN	prosite domains	PS00213	11	1	12186	43	PTGDS
3.828e-02	-3.26	C4-dicarboxylate transmembrane transporter activity	molecular function	GO:0015556	15	1	18094	47	SLC25A18
3.828e-02	-3.26	AMP binding	molecular function	GO:0016208	15	1	18094	47	ACSS1
3.828e-02	-3.26	phosphatidylglycerol binding	molecular function	GO:1901611	15	1	18094	47	PITPNC1
3.844e-02	-3.26	SPSB4 (splA/ryanodine receptor domain and SOCS box containing 4)	protein interactions	92369	123	2	19454	49	PCDH9,LRIG1
3.849e-02	-3.26	Wnt signaling pathway	biological process	GO:0016055	283	3	18204	48	CTNND2,TNIK,ZNRF3
3.850e-02	-3.26	Ig-like_dom_sf	interpro domains	IPR036179	483	4	18521	49	FGFR3,LRIG1,NTM,LSAMP
3.851e-02	-3.26	Cell-type Dependent Selectivity of CCK2R Signaling	WikiPathways	WP3679	13	1	5310	16	RYR3
3.866e-02	-3.25	human chr13q31.3	chromosome location	human chr13q31.3	21	1	26134	49	GPC5
3.872e-02	-3.25	synapse assembly	biological process	GO:0007416	118	2	18204	48	GPM6A,NRXN1
3.884e-02	-3.25	synapse maturation	biological process	GO:0060074	15	1	18204	48	NFIA
3.884e-02	-3.25	exit from mitosis	biological process	GO:0010458	15	1	18204	48	NFIA
3.884e-02	-3.25	cerebellar Purkinje cell layer formation	biological process	GO:0021694	15	1	18204	48	RORA
3.884e-02	-3.25	sarcoplasmic reticulum calcium ion transport	biological process	GO:0070296	15	1	18204	48	RYR3
3.884e-02	-3.25	regulation of circadian sleep/wake cycle, sleep	biological process	GO:0045187	15	1	18204	48	PTGDS
3.884e-02	-3.25	chondrocyte proliferation	biological process	GO:0035988	15	1	18204	48	FGFR3
3.884e-02	-3.25	protein homotrimerization	biological process	GO:0070207	15	1	18204	48	SLC1A2
3.884e-02	-3.25	positive regulation of glycogen biosynthetic process	biological process	GO:0045725	15	1	18204	48	SORBS1
3.884e-02	-3.25	negative regulation of sodium ion transmembrane transport	biological process	GO:1902306	15	1	18204	48	ATP1A2
3.884e-02	-3.25	intracellular potassium ion homeostasis	biological process	GO:0030007	15	1	18204	48	ATP1A2
3.884e-02	-3.25	response to caffeine	biological process	GO:0031000	15	1	18204	48	RYR3
3.884e-02	-3.25	neuroblast division	biological process	GO:0055057	15	1	18204	48	SOX5
3.887e-02	-3.25	striated_muscle	COSMIC cancer mutations	striated_muscle	4228	18	16828	48	SLC1A3,RORA,RYR3,PARD3B,NPAS3,FGFR3,GLIS3,CDH20,ZNRF3,CTNND2,NFIA,CAMK2G,COL5A3,SORBS1,PAMR1,NHSL1,SPARCL1,PARD3
3.894e-02	-3.25	COLFI	smart domains	SM00038	11	1	9717	35	COL5A3
3.897e-02	-3.24	NTF2-like_dom_sf	interpro domains	IPR032710	15	1	18521	49	CAMK2G
3.897e-02	-3.24	CNH_dom	interpro domains	IPR001180	15	1	18521	49	TNIK
3.897e-02	-3.24	ATPase_P-typ_cation-transptr_C	interpro domains	IPR006068	15	1	18521	49	ATP1A2
3.922e-02	-3.24	soft_tissue-small_round_cell_tumour	COSMIC cancer mutations	soft_tissue-small_round_cell_tumour	14	1	16828	48	FGFR3
3.922e-02	-3.24	endometriosis	COSMIC cancer mutations	endometriosis	14	1	16828	48	FGFR3
3.922e-02	-3.24	small_round_cell_tumour	COSMIC cancer mutations	small_round_cell_tumour	14	1	16828	48	FGFR3
3.922e-02	-3.24	in_situ_neoplasm	COSMIC cancer mutations	in_situ_neoplasm	14	1	16828	48	FGFR3
3.922e-02	-3.24	urinary_tract-renal_pelvis-carcinoma-transitional_cell_carcinoma	COSMIC cancer mutations	urinary_tract-renal_pelvis-carcinoma-transitional_cell_carcinoma	14	1	16828	48	FGFR3
3.935e-02	-3.24	skin-acral-malignant_melanoma	COSMIC cancer mutations	skin-acral-malignant_melanoma	264	3	16828	48	CDH20,COL5A3,PARD3
3.946e-02	-3.23	postsynaptic density, intracellular component	cellular component	GO:0099092	16	1	19108	48	TNIK
3.956e-02	-3.23	SAPCD1 (suppressor APC domain containing 1)	protein interactions	401251	16	1	19454	49	CTNNA2
3.956e-02	-3.23	VGLL1 (vestigial like family member 1)	protein interactions	51442	16	1	19454	49	MEIS2
3.956e-02	-3.23	GALNT13 (polypeptide N-acetylgalactosaminyltransferase 13)	protein interactions	114805	16	1	19454	49	TNIK
3.956e-02	-3.23	SYTL2 (synaptotagmin like 2)	protein interactions	54843	16	1	19454	49	NRXN1
3.956e-02	-3.23	TWIST2 (twist family bHLH transcription factor 2)	protein interactions	117581	16	1	19454	49	ZBTB20
3.956e-02	-3.23	FZD4 (frizzled class receptor 4)	protein interactions	8322	16	1	19454	49	ZNRF3
3.956e-02	-3.23	CAMK1G (calcium/calmodulin dependent protein kinase IG)	protein interactions	57172	16	1	19454	49	CAMK2G
3.956e-02	-3.23	DUS1L (dihydrouridine synthase 1 like)	protein interactions	64118	16	1	19454	49	CAMK2G
3.956e-02	-3.23	CDH12 (cadherin 12)	protein interactions	1010	16	1	19454	49	CTNNA2
3.956e-02	-3.23	NBL1 (NBL1, DAN family BMP antagonist)	protein interactions	4681	16	1	19454	49	LRIG1
3.956e-02	-3.23	SYT9 (synaptotagmin 9)	protein interactions	143425	16	1	19454	49	NRXN1
3.956e-02	-3.23	SYT4 (synaptotagmin 4)	protein interactions	6860	16	1	19454	49	NRXN1
3.956e-02	-3.23	FNDC8 (fibronectin type III domain containing 8)	protein interactions	54752	16	1	19454	49	SPARCL1
3.956e-02	-3.23	HLA-H (major histocompatibility complex, class I, H (pseudogene))	protein interactions	3136	16	1	19454	49	FGFR3
3.956e-02	-3.23	CTSK (cathepsin K)	protein interactions	1513	16	1	19454	49	FGFR3
3.961e-02	-3.23	Glutamatergic synapse	KEGG pathways	ko04724	114	2	7161	20	SLC1A3,SLC1A2
3.961e-02	-3.23	Glutamatergic synapse	KEGG pathways	hsa04724	114	2	7161	20	SLC1A3,SLC1A2
3.992e-02	-3.22	regulation of nervous system process	biological process	GO:0031644	120	2	18204	48	PARD3,NRXN1
3.995e-02	-3.22	bicellular tight junction	cellular component	GO:0005923	126	2	19108	48	PARD3B,PARD3
4.010e-02	-3.22	DCC mediated attractive signaling	REACTOME pathways	R-HSA-418885	14	1	10285	30	ABLIM1
4.010e-02	-3.22	large_intestine-adenoma	COSMIC cancer mutations	large_intestine-adenoma	266	3	16828	48	RYR3,SOX5,CDH20
4.016e-02	-3.21	SYP (synaptophysin)	protein interactions	6855	126	2	19454	49	GPM6A,PITPNC1
4.017e-02	-3.21	ovary-carcinoma-clear_cell_carcinoma	COSMIC cancer mutations	ovary-carcinoma-clear_cell_carcinoma	665	5	16828	48	TNIK,BMPR1B,FGFR3,CAMK2G,SPARCL1
4.053e-02	-3.21	CNH	pfam domains	PF00780	15	1	17795	49	TNIK
4.053e-02	-3.21	Cation_ATPase_C	pfam domains	PF00689	15	1	17795	49	ATP1A2
4.059e-02	-3.20	ovary-carcinoma-mucinous_carcinoma	COSMIC cancer mutations	ovary-carcinoma-mucinous_carcinoma	456	4	16828	48	FGFR3,BMPR1B,CAMK2G,TNIK
4.067e-02	-3.20	TRIM67 (tripartite motif containing 67)	protein interactions	440730	4804	18	19454	49	ACSS1,PARD3,ATP1A2,CTNNA2,MSI2,CTNND2,NTM,PITPNC1,TNIK,SLC25A18,SLC1A3,CAMK2G,SLC4A4,LRIG1,AHCYL2,GPM6A,LSAMP,DTNA
4.077e-02	-3.20	non_small_cell_carcinoma	COSMIC cancer mutations	non_small_cell_carcinoma	5198	21	16828	48	MSI2,FBXL7,COL5A3,CAMK2G,CTNND2,PITPNC1,LSAMP,BMPR1B,PARD3,ATP13A4,LRIG1,SPARCL1,PRODH,FGFR3,NPAS3,SOX5,HIF3A,RORA,TNIK,SLC1A3,ABLIM1
4.077e-02	-3.20	lung-carcinoma-non_small_cell_carcinoma	COSMIC cancer mutations	lung-carcinoma-non_small_cell_carcinoma	5198	21	16828	48	FGFR3,NPAS3,SOX5,RORA,HIF3A,TNIK,SLC1A3,ABLIM1,MSI2,FBXL7,COL5A3,CAMK2G,CTNND2,PITPNC1,LSAMP,BMPR1B,PARD3,ATP13A4,LRIG1,SPARCL1,PRODH
4.078e-02	-3.20	oxysterol binding	molecular function	GO:0008142	16	1	18094	47	RORA
4.079e-02	-3.20	cellular response to growth factor stimulus	biological process	GO:0071363	494	4	18204	48	NFIA,SOX5,FGFR3,BMPR1B
4.085e-02	-3.20	acral	COSMIC cancer mutations	acral	268	3	16828	48	CDH20,COL5A3,PARD3
4.105e-02	-3.19	clear_cell_carcinoma	COSMIC cancer mutations	clear_cell_carcinoma	669	5	16828	48	FGFR3,BMPR1B,SPARCL1,CAMK2G,TNIK
4.108e-02	-3.19	CARM1 (coactivator associated arginine methyltransferase 1)	protein interactions	10498	304	3	19454	49	DTNA,CAMK2G,RORA
4.114e-02	-3.19	mucinous_carcinoma	COSMIC cancer mutations	mucinous_carcinoma	458	4	16828	48	TNIK,FGFR3,BMPR1B,CAMK2G
4.124e-02	-3.19	cation binding	molecular function	GO:0043169	4341	17	18094	47	NRXN1,PCDH9,PAMR1,SLC1A2,ABLIM1,ATP1A2,ACSS1,ZBTB20,RYR3,ATP13A4,GLIS3,SPARCL1,RORA,DTNA,BMPR1B,SLC1A3,ZNRF3
4.132e-02	-3.19	SYT2 (synaptotagmin 2)	protein interactions	127833	128	2	19454	49	NRXN1,AHCYL2
4.138e-02	-3.18	non-proteinogenic amino acid biosynthetic process	biological process	GO:0170043	16	1	18204	48	SLC1A3
4.138e-02	-3.18	neuron cell-cell adhesion	biological process	GO:0007158	16	1	18204	48	NRXN1
4.138e-02	-3.18	locomotory exploration behavior	biological process	GO:0035641	16	1	18204	48	ATP1A2
4.138e-02	-3.18	S-adenosylmethionine metabolic process	biological process	GO:0046500	16	1	18204	48	AHCYL2
4.138e-02	-3.18	regulation of Wnt signaling pathway, planar cell polarity pathway	biological process	GO:2000095	16	1	18204	48	ZNRF3
4.138e-02	-3.18	regulation of amino acid transmembrane transport	biological process	GO:1903789	16	1	18204	48	ATP1A2
4.138e-02	-3.18	regulation of amino acid import across plasma membrane	biological process	GO:0010958	16	1	18204	48	ATP1A2
4.138e-02	-3.18	short-chain fatty acid metabolic process	biological process	GO:0046459	16	1	18204	48	ACSS1
4.138e-02	-3.18	regulation of respiratory system process	biological process	GO:0044065	16	1	18204	48	ATP1A2
4.138e-02	-3.18	nonribosomal peptide biosynthetic process	biological process	GO:0019184	16	1	18204	48	SLC1A2
4.154e-02	-3.18	cell population proliferation	biological process	GO:0008283	726	5	18204	48	RORA,ZNRF3,SOX5,FGFR3,NFIA
4.190e-02	-3.17	Lima1 (LIM domain and actin binding 1)	protein interactions	65970	129	2	19454	49	ABLIM1,ZBTB20
4.190e-02	-3.17	CHD7 (chromodomain helicase DNA binding protein 7)	protein interactions	55636	129	2	19454	49	ZBTB20,SOX5
4.196e-02	-3.17	ureter	COSMIC cancer mutations	ureter	15	1	16828	48	FGFR3
4.198e-02	-3.17	KRTAP19-3 (keratin associated protein 19-3)	protein interactions	337970	17	1	19454	49	CAMK2G
4.198e-02	-3.17	Shcbp1 (Shc SH2-domain binding protein 1)	protein interactions	20419	17	1	19454	49	GPC5
4.198e-02	-3.17	PAX4 (paired box 4)	protein interactions	5078	17	1	19454	49	NTM
4.198e-02	-3.17	RASL12 (RAS like family 12)	protein interactions	51285	17	1	19454	49	BMPR1B
4.198e-02	-3.17	Sqstm1 (sequestosome 1)	protein interactions	18412	17	1	19454	49	BMPR1B
4.198e-02	-3.17	FAM163B (family with sequence similarity 163 member B)	protein interactions	642968	17	1	19454	49	CAMK2G
4.198e-02	-3.17	MSANTD2 (Myb/SANT DNA binding domain containing 2)	protein interactions	79684	17	1	19454	49	SOX5
4.198e-02	-3.17	SEPSECS (Sep (O-phosphoserine) tRNA:Sec (selenocysteine) tRNA synthase)	protein interactions	51091	17	1	19454	49	ABLIM1
4.198e-02	-3.17	DPP6 (dipeptidyl peptidase like 6)	protein interactions	1804	17	1	19454	49	GPM6A
4.198e-02	-3.17	TAGAP (T cell activation RhoGTPase activating protein)	protein interactions	117289	17	1	19454	49	DTNA
4.203e-02	-3.17	acute_lymphoblastic_leukaemia	COSMIC cancer mutations	acute_lymphoblastic_leukaemia	2197	11	16828	48	PARD3B,FGFR3,SOX5,TNIK,DTNA,SLC4A4,CAMK2G,SLC25A18,NFIA,BMPR1B,ATP1A2
4.233e-02	-3.16	skeletal system development	biological process	GO:0001501	500	4	18204	48	NFIA,SOX5,FGFR3,BMPR1B
4.236e-02	-3.16	positive regulation of lipid metabolic process	biological process	GO:0045834	124	2	18204	48	ZBTB20,SORBS1
4.240e-02	-3.16	DWA	smart domains	SM00523	12	1	9717	35	NFIA
4.249e-02	-3.16	DVL1 (dishevelled segment polarity protein 1)	protein interactions	1855	130	2	19454	49	PARD3,ZNRF3
4.282e-02	-3.15	ovary-carcinoma-endometrioid_carcinoma	COSMIC cancer mutations	ovary-carcinoma-endometrioid_carcinoma	464	4	16828	48	FGFR3,BMPR1B,CAMK2G,TNIK
4.286e-02	-3.15	tight junction	cellular component	GO:0070160	131	2	19108	48	PARD3B,PARD3
4.290e-02	-3.15	Synthesis of Prostaglandins (PG) and Thromboxanes (TX)	REACTOME pathways	R-HSA-2162123	15	1	10285	30	PTGDS
4.294e-02	-3.15	Helix-loop-helix DNA-binding domain	gene3d domains	4.10.280.10	111	2	14470	43	HIF3A,NPAS3
4.308e-02	-3.14	ZNF609 (zinc finger protein 609)	protein interactions	23060	131	2	19454	49	SOX5,NFIA
4.308e-02	-3.14	TRPS1 (transcriptional repressor GATA binding 1)	protein interactions	7227	131	2	19454	49	SOX5,NFIA
4.308e-02	-3.14	NCOA2 (nuclear receptor coactivator 2)	protein interactions	10499	131	2	19454	49	NFIA,RORA
4.315e-02	-3.14	PROTEIN_KINASE_ATP	prosite domains	PS00107	377	4	12186	43	CAMK2G,BMPR1B,FGFR3,TNIK
4.339e-02	-3.14	signaling	biological process	GO:0023052	4968	19	18204	48	RORA,TNIK,ATP1A2,DTNA,FGFR3,RYR3,PITPNC1,ZNRF3,SLC1A2,PARD3,CAMK2G,BMPR1B,SORBS1,PRODH,CTNND2,NRXN1,SPARCL1,NFIA,SLC1A3
4.340e-02	-3.14	muscle system process	biological process	GO:0003012	297	3	18204	48	ATP1A2,DTNA,RYR3
4.364e-02	-3.13	cellular response to organonitrogen compound	biological process	GO:0071417	505	4	18204	48	SLC1A2,SORBS1,SLC1A3,RYR3
4.367e-02	-3.13	STRN (striatin)	protein interactions	6801	132	2	19454	49	CAMK2G,TNIK
4.391e-02	-3.13	cGMP metabolic process	biological process	GO:0046068	17	1	18204	48	RORA
4.391e-02	-3.13	protein trimerization	biological process	GO:0070206	17	1	18204	48	SLC1A2
4.391e-02	-3.13	positive regulation of glycogen metabolic process	biological process	GO:0070875	17	1	18204	48	SORBS1
4.391e-02	-3.13	membrane depolarization during cardiac muscle cell action potential	biological process	GO:0086012	17	1	18204	48	ATP1A2
4.391e-02	-3.13	viral genome replication	biological process	GO:0019079	17	1	18204	48	NFIA
4.391e-02	-3.13	cell migration in hindbrain	biological process	GO:0021535	17	1	18204	48	CTNNA2
4.391e-02	-3.13	T-helper 17 type immune response	biological process	GO:0072538	17	1	18204	48	RORA
4.391e-02	-3.13	cellular response to ATP	biological process	GO:0071318	17	1	18204	48	RYR3
4.391e-02	-3.13	microvillus assembly	biological process	GO:0030033	17	1	18204	48	TNIK
4.391e-02	-3.13	ureter development	biological process	GO:0072189	17	1	18204	48	NFIA
4.391e-02	-3.13	cell communication by electrical coupling involved in cardiac conduction	biological process	GO:0086064	17	1	18204	48	ATP1A2
4.406e-02	-3.12	PAC	interpro domains	IPR001610	17	1	18521	49	HIF3A
4.406e-02	-3.12	AMP-bd_C	interpro domains	IPR025110	17	1	18521	49	ACSS1
4.422e-02	-3.12	cell-cell junction assembly	biological process	GO:0007043	127	2	18204	48	CDH20,PARD3
4.440e-02	-3.11	Tgfbr1 (transforming growth factor, beta receptor I)	protein interactions	21812	18	1	19454	49	BMPR1B
4.440e-02	-3.11	OPCML (opioid binding protein/cell adhesion molecule like)	protein interactions	4978	18	1	19454	49	NTM
4.440e-02	-3.11	NKIRAS1 (NFKB inhibitor interacting Ras like 1)	protein interactions	28512	18	1	19454	49	BMPR1B
4.440e-02	-3.11	KLHL1 (kelch like family member 1)	protein interactions	57626	18	1	19454	49	BMPR1B
4.440e-02	-3.11	PTGFR (prostaglandin F receptor)	protein interactions	5737	18	1	19454	49	PTGDS
4.444e-02	-3.11	circulatory system process	biological process	GO:0003013	508	4	18204	48	ATP1A2,SLC1A3,SLC1A2,SLC4A4
4.448e-02	-3.11	PDZ	pfam domains	PF00595	122	2	17795	49	PARD3,PARD3B
4.469e-02	-3.11	renal_pelvis	COSMIC cancer mutations	renal_pelvis	16	1	16828	48	FGFR3
4.469e-02	-3.11	urinary_tract-carcinoma	COSMIC cancer mutations	urinary_tract-carcinoma	16	1	16828	48	FGFR3
4.469e-02	-3.11	flank	COSMIC cancer mutations	flank	16	1	16828	48	FGFR3
4.469e-02	-3.11	normal	COSMIC cancer mutations	normal	16	1	16828	48	FGFR3
4.487e-02	-3.10	NUFIP1 (nuclear FMR1 interacting protein 1)	protein interactions	26747	134	2	19454	49	GPM6A,NTM
4.506e-02	-3.10	Cadherins	gene3d domains	2.60.40.60	114	2	14470	43	PCDH9,CDH20
4.547e-02	-3.09	FOXP1 (forkhead box P1)	protein interactions	27086	135	2	19454	49	SOX5,NFIA
4.547e-02	-3.09	Myo1c (myosin IC)	protein interactions	17913	135	2	19454	49	CAMK2G,ABLIM1
4.576e-02	-3.08	phosphatidylcholine transporter activity	molecular function	GO:0008525	18	1	18094	47	PITPNC1
4.576e-02	-3.08	intracellularly gated calcium channel activity	molecular function	GO:0015278	18	1	18094	47	RYR3
4.581e-02	-3.08	AMP-binding_C	pfam domains	PF13193	17	1	17795	49	ACSS1
4.581e-02	-3.08	ZZ	pfam domains	PF00569	17	1	17795	49	DTNA
4.629e-02	-3.07	Hypoxic and oxygen homeostasis regulation of HIF-1-alpha	Pathway Interaction DB	hif1apathway	15	1	2226	7	HIF3A
4.629e-02	-3.07	parathyroid	COSMIC cancer mutations	parathyroid	476	4	16828	48	RYR3,GPC5,GPM6A,PAMR1
4.643e-02	-3.07	positive regulation of myelination	biological process	GO:0031643	18	1	18204	48	PARD3
4.643e-02	-3.07	non-proteinogenic amino acid catabolic process	biological process	GO:0170044	18	1	18204	48	PRODH
4.643e-02	-3.07	positive regulation of circadian rhythm	biological process	GO:0042753	18	1	18204	48	RORA
4.643e-02	-3.07	receptor catabolic process	biological process	GO:0032801	18	1	18204	48	ZNRF3
4.643e-02	-3.07	negative regulation of sodium ion transport	biological process	GO:0010766	18	1	18204	48	ATP1A2
4.643e-02	-3.07	dendritic spine morphogenesis	biological process	GO:0060997	18	1	18204	48	CTNND2
4.659e-02	-3.07	Leu-rich_rpt_Cys-con_subtyp	interpro domains	IPR006553	18	1	18521	49	FBXL7
4.659e-02	-3.07	Leu-rich_rpt_4	interpro domains	IPR025875	18	1	18521	49	LRIG1
4.661e-02	-3.07	cell division	biological process	GO:0051301	516	4	18204	48	FBXL7,SOX5,PARD3,PARD3B
4.669e-02	-3.06	parallel fiber to Purkinje cell synapse	cellular component	GO:0098688	19	1	19108	48	GPM6A
4.669e-02	-3.06	postsynaptic specialization, intracellular component	cellular component	GO:0099091	19	1	19108	48	TNIK
4.669e-02	-3.06	cation-transporting ATPase complex	cellular component	GO:0090533	19	1	19108	48	ATP1A2
4.669e-02	-3.06	astrocyte projection	cellular component	GO:0097449	19	1	19108	48	SLC1A2
4.669e-02	-3.06	TBL1X (transducin beta like 1 X-linked)	protein interactions	6907	137	2	19454	49	SOX5,NFIA
4.671e-02	-3.06	EF-hand	gene3d domains	1.10.238.10	272	3	14470	43	RYR3,DTNA,SPARCL1
4.681e-02	-3.06	PHYHIPL (phytanoyl-CoA 2-hydroxylase interacting protein like)	protein interactions	84457	19	1	19454	49	GPM6A
4.681e-02	-3.06	RIT2 (Ras like without CAAX 2)	protein interactions	6014	19	1	19454	49	DTNA
4.681e-02	-3.06	INKA1 (inka box actin regulator 1)	protein interactions	389119	19	1	19454	49	ZBTB20
4.681e-02	-3.06	NLGN1 (neuroligin 1)	protein interactions	22871	19	1	19454	49	NRXN1
4.681e-02	-3.06	SPZ1 (spermatogenic leucine zipper 1)	protein interactions	84654	19	1	19454	49	DTNA
4.681e-02	-3.06	C3orf62 (chromosome 3 open reading frame 62)	protein interactions	375341	19	1	19454	49	ATP1A2
4.681e-02	-3.06	RRAD (RRAD, Ras related glycolysis inhibitor and calcium channel regulator)	protein interactions	6236	19	1	19454	49	CAMK2G
4.681e-02	-3.06	Mtx1 (metaxin 1)	protein interactions	17827	19	1	19454	49	CAMK2G
4.681e-02	-3.06	LTC4S (leukotriene C4 synthase)	protein interactions	4056	19	1	19454	49	CAMK2G
4.681e-02	-3.06	SYT7 (synaptotagmin 7)	protein interactions	9066	19	1	19454	49	NRXN1
4.695e-02	-3.06	cell communication	biological process	GO:0007154	5010	19	18204	48	RORA,TNIK,DTNA,ATP1A2,FGFR3,RYR3,PITPNC1,ZNRF3,SLC1A2,PARD3,CAMK2G,BMPR1B,PRODH,SORBS1,CTNND2,NRXN1,SPARCL1,NFIA,SLC1A3
4.730e-02	-3.05	NFIB (nuclear factor I B)	protein interactions	4781	138	2	19454	49	NFIA,SOX5
4.734e-02	-3.05	NAD+ Signalling and Aging	SMPDB pathways	SMP0084271	11	1	1369	6	RORA
4.742e-02	-3.05	non_chronically_sun_exposed_site	COSMIC cancer mutations	non_chronically_sun_exposed_site	17	1	16828	48	FGFR3
4.742e-02	-3.05	skin-carcinoma-squamous_cell_carcinoma_BRAF_inhibitor_related	COSMIC cancer mutations	skin-carcinoma-squamous_cell_carcinoma_BRAF_inhibitor_related	17	1	16828	48	FGFR3
4.742e-02	-3.05	skin-other-verrucal_keratosis_BRAF_inhibitor_related	COSMIC cancer mutations	skin-other-verrucal_keratosis_BRAF_inhibitor_related	17	1	16828	48	FGFR3
4.742e-02	-3.05	squamous_cell_carcinoma_BRAF_inhibitor_related	COSMIC cancer mutations	squamous_cell_carcinoma_BRAF_inhibitor_related	17	1	16828	48	FGFR3
4.742e-02	-3.05	verrucal_keratosis_BRAF_inhibitor_related	COSMIC cancer mutations	verrucal_keratosis_BRAF_inhibitor_related	17	1	16828	48	FGFR3
4.742e-02	-3.05	breast-carcinoma-neuroendocrine_carcinoma	COSMIC cancer mutations	breast-carcinoma-neuroendocrine_carcinoma	17	1	16828	48	FGFR3
4.742e-02	-3.05	skin-non_chronically_sun_exposed_site-malignant_melanoma	COSMIC cancer mutations	skin-non_chronically_sun_exposed_site-malignant_melanoma	17	1	16828	48	FGFR3
4.765e-02	-3.04	human chr18q12.1	chromosome location	human chr18q12.1	26	1	26134	49	DTNA
4.789e-02	-3.04	Ser/Thr_kinase_AS	interpro domains	IPR008271	308	3	18521	49	CAMK2G,BMPR1B,TNIK
4.792e-02	-3.04	KRTAP9-3 (keratin associated protein 9-3)	protein interactions	83900	139	2	19454	49	NTM,SLC25A18
4.802e-02	-3.04	ductal_carcinoma	COSMIC cancer mutations	ductal_carcinoma	15798	48	16828	48	ACSS1,AHCYL2,RYR3,SLC1A2,PARD3B,PRODH,SORBS1,SPARCL1,SFXN5,LSAMP,PITPNC1,NFIA,NKAIN3,MEIS2,SLC4A4,GPM6A,SOX5,RFX4,PTGDS,ATP1A2,LRIG1,BMPR1B,ZNRF3,CTNND2,SLC25A18,CAMK2G,ABLIM1,DTNA,SLC1A3,TNIK,NPAS3,PCDH9,NRXN1,ATP13A4,CDH20,GLIS3,ZBTB20,MSI2,HIF3A,RORA,NTM,FGFR3,PAMR1,NHSL1,PARD3,COL5A3,GPC5,FBXL7
4.804e-02	-3.04	regulation of sequestering of calcium ion	biological process	GO:0051282	133	2	18204	48	ATP1A2,RYR3
4.824e-02	-3.03	alkali metal ion binding	molecular function	GO:0031420	19	1	18094	47	ATP1A2
4.824e-02	-3.03	transmembrane receptor protein serine/threonine kinase activity	molecular function	GO:0004675	19	1	18094	47	BMPR1B
4.834e-02	-3.03	Ser-Thr/Tyr_kinase_cat_dom	interpro domains	IPR001245	133	2	18521	49	BMPR1B,FGFR3
4.844e-02	-3.03	LRR_4	pfam domains	PF12799	18	1	17795	49	LRIG1
4.848e-02	-3.03	TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)	REACTOME pathways	R-HSA-2173791	17	1	10285	30	PARD3
4.848e-02	-3.03	Unblocking of NMDA receptor, glutamate binding and activation	REACTOME pathways	R-HSA-438066	17	1	10285	30	CAMK2G
4.848e-02	-3.03	CREB phosphorylation through the activation of CaMKII	REACTOME pathways	R-HSA-442729	17	1	10285	30	CAMK2G
4.853e-02	-3.03	CEP89 (centrosomal protein 89)	protein interactions	84902	140	2	19454	49	ABLIM1,PARD3
4.853e-02	-3.03	KIF7 (kinesin family member 7)	protein interactions	374654	140	2	19454	49	PARD3,TNIK
4.853e-02	-3.03	WDR48 (WD repeat domain 48)	protein interactions	57599	140	2	19454	49	AHCYL2,FBXL7
4.853e-02	-3.03	SATB2 (SATB homeobox 2)	protein interactions	23314	140	2	19454	49	SOX5,NFIA
4.860e-02	-3.02	sulfur compound metabolic process	biological process	GO:0006790	311	3	18204	48	AHCYL2,ACSS1,SLC1A2
4.866e-02	-3.02	calcium ion transmembrane transporter activity	molecular function	GO:0015085	136	2	18094	47	GPM6A,RYR3
4.869e-02	-3.02	establishment of cell polarity	biological process	GO:0030010	134	2	18204	48	PARD3,PARD3B
4.895e-02	-3.02	negative regulation of peptidyl-threonine phosphorylation	biological process	GO:0010801	19	1	18204	48	PARD3
4.895e-02	-3.02	cerebellar Purkinje cell layer morphogenesis	biological process	GO:0021692	19	1	18204	48	RORA
4.895e-02	-3.02	response to potassium ion	biological process	GO:0035864	19	1	18204	48	ATP1A2
4.895e-02	-3.02	regulation of circadian sleep/wake cycle	biological process	GO:0042749	19	1	18204	48	PTGDS
4.895e-02	-3.02	microvillus organization	biological process	GO:0032528	19	1	18204	48	TNIK
4.895e-02	-3.02	excitatory synapse assembly	biological process	GO:1904861	19	1	18204	48	NRXN1
4.895e-02	-3.02	vocalization behavior	biological process	GO:0071625	19	1	18204	48	NRXN1
4.895e-02	-3.02	regulation of neurotransmitter uptake	biological process	GO:0051580	19	1	18204	48	ATP1A2
4.910e-02	-3.01	Kinase-like_dom_sf	interpro domains	IPR011009	523	4	18521	49	TNIK,CAMK2G,BMPR1B,FGFR3
4.911e-02	-3.01	Znf_ZZ	interpro domains	IPR000433	19	1	18521	49	DTNA
4.911e-02	-3.01	Znf_ZZ_sf	interpro domains	IPR043145	19	1	18521	49	DTNA
4.916e-02	-3.01	SNTB2 (syntrophin beta 2)	protein interactions	6645	141	2	19454	49	FGFR3,DTNA
4.916e-02	-3.01	UPK2 (uroplakin 2)	protein interactions	7379	141	2	19454	49	PCDH9,CTNNA2
4.916e-02	-3.01	MAB21L2 (mab-21 like 2)	protein interactions	10586	141	2	19454	49	MEIS2,CTNNA2
4.921e-02	-3.01	OXT (oxytocin/neurophysin I prepropeptide)	protein interactions	5020	20	1	19454	49	FGFR3
4.921e-02	-3.01	ZNF488 (zinc finger protein 488)	protein interactions	118738	20	1	19454	49	CAMK2G
4.921e-02	-3.01	BMP6 (bone morphogenetic protein 6)	protein interactions	654	20	1	19454	49	BMPR1B
4.921e-02	-3.01	HOXA13 (homeobox A13)	protein interactions	3209	20	1	19454	49	MEIS2
4.921e-02	-3.01	ANXA13 (annexin A13)	protein interactions	312	20	1	19454	49	MSI2
4.921e-02	-3.01	CCKBR (cholecystokinin B receptor)	protein interactions	887	20	1	19454	49	NTM
4.921e-02	-3.01	Kif1c (kinesin family member 1C)	protein interactions	16562	20	1	19454	49	ABLIM1
4.921e-02	-3.01	NCAM2 (neural cell adhesion molecule 2)	protein interactions	4685	20	1	19454	49	CTNND2
4.921e-02	-3.01	RNF183 (ring finger protein 183)	protein interactions	138065	20	1	19454	49	PTGDS
4.921e-02	-3.01	MLC1 (modulator of VRAC current 1)	protein interactions	23209	20	1	19454	49	DTNA
4.921e-02	-3.01	ADRA1D (adrenoceptor alpha 1D)	protein interactions	146	20	1	19454	49	DTNA
4.921e-02	-3.01	FAM13C (family with sequence similarity 13 member C)	protein interactions	220965	20	1	19454	49	AHCYL2
4.921e-02	-3.01	ADRA2C (adrenoceptor alpha 2C)	protein interactions	152	20	1	19454	49	MEIS2
4.921e-02	-3.01	CACFD1 (calcium channel flower domain containing 1)	protein interactions	11094	20	1	19454	49	PITPNC1
4.921e-02	-3.01	SNX20 (sorting nexin 20)	protein interactions	124460	20	1	19454	49	AHCYL2
4.921e-02	-3.01	PON1 (paraoxonase 1)	protein interactions	5444	20	1	19454	49	SFXN5
4.930e-02	-3.01	CNH	smart domains	SM00036	14	1	9717	35	TNIK
4.930e-02	-3.01	4.1m	smart domains	SM00294	14	1	9717	35	NRXN1
4.936e-02	-3.01	-	gene3d domains	2.60.120.1000	17	1	14470	43	COL5A3
4.943e-02	-3.01	human chr2p12	chromosome location	human chr2p12	27	1	26134	49	CTNNA2
4.952e-02	-3.01	adrenal_cortical_carcinoma	COSMIC cancer mutations	adrenal_cortical_carcinoma	2256	11	16828	48	SOX5,RFX4,SLC1A2,MEIS2,ZNRF3,CTNND2,ZBTB20,PCDH9,NHSL1,ATP1A2,LRIG1
4.954e-02	-3.01	DCAF7 (DDB1 and CUL4 associated factor 7)	protein interactions	10238	328	3	19454	49	SOX5,BMPR1B,PARD3
4.961e-02	-3.00	testis-germ_cell_tumour-non_seminoma	COSMIC cancer mutations	testis-germ_cell_tumour-non_seminoma	487	4	16828	48	TNIK,CAMK2G,BMPR1B,FGFR3
4.963e-02	-3.00	medullary_carcinoma	COSMIC cancer mutations	medullary_carcinoma	290	3	16828	48	SLC1A2,PARD3B,FGFR3
4.963e-02	-3.00	thyroid-carcinoma-medullary_carcinoma	COSMIC cancer mutations	thyroid-carcinoma-medullary_carcinoma	290	3	16828	48	SLC1A2,PARD3B,FGFR3
4.978e-02	-3.00	STRN3 (striatin 3)	protein interactions	29966	142	2	19454	49	CAMK2G,TNIK
4.983e-02	-3.00	PK_Tyr_Ser-Thr	pfam domains	PF07714	130	2	17795	49	BMPR1B,FGFR3
4.999e-02	-3.00	proton transmembrane transport	biological process	GO:1902600	136	2	18204	48	SLC25A18,ATP1A2
4.999e-02	-3.00	cell-matrix adhesion	biological process	GO:0007160	136	2	18204	48	COL5A3,SORBS1