P-value | ln(P) | Term | GO Tree | GO ID | # of Genes in Term | # of Target Genes in Term | # of Total Genes | # of Target Genes | Common Genes |
3.250e-10 | -21.85 | respiratory electron transport chain | biological process | GO:0022904 | 102 | 8 | 18204 | 50 |
NDUFB2,SNCA,ETFB,COX5B,COX6A1,UQCR10,NDUFA5,NDUFA1 |
6.902e-10 | -21.09 | electron transport chain | biological process | GO:0022900 | 112 | 8 | 18204 | 50 |
NDUFB2,COX5B,NDUFA1,UQCR10,NDUFA5,COX6A1,ETFB,SNCA |
2.078e-09 | -19.99 | mitochondrial ATP synthesis coupled electron transport | biological process | GO:0042775 | 80 | 7 | 18204 | 50 |
COX6A1,COX5B,NDUFB2,SNCA,NDUFA1,NDUFA5,UQCR10 |
2.078e-09 | -19.99 | ATP synthesis coupled electron transport | biological process | GO:0042773 | 80 | 7 | 18204 | 50 |
COX5B,NDUFB2,NDUFA5,UQCR10,NDUFA1,SNCA,COX6A1 |
6.261e-09 | -18.89 | Respiratory electron transport | REACTOME pathways | R-HSA-611105 | 92 | 7 | 10285 | 30 |
COX5B,UQCR10,NDUFA5,NDUFB2,NDUFA1,COX6A1,ETFB |
1.328e-08 | -18.14 | Oxidative phosphorylation | KEGG pathways | ko00190 | 120 | 7 | 7161 | 19 |
UQCR10,ATP6V0B,NDUFA5,COX5B,NDUFA1,NDUFB2,COX6A1 |
1.328e-08 | -18.14 | Oxidative phosphorylation | KEGG pathways | hsa00190 | 120 | 7 | 7161 | 19 |
NDUFB2,COX6A1,COX5B,NDUFA5,UQCR10,ATP6V0B,NDUFA1 |
1.413e-08 | -18.07 | oxidative phosphorylation | biological process | GO:0006119 | 105 | 7 | 18204 | 50 |
SNCA,COX6A1,COX5B,NDUFB2,NDUFA5,UQCR10,NDUFA1 |
2.201e-08 | -17.63 | Parkinson's disease | KEGG pathways | hsa05012 | 129 | 7 | 7161 | 19 |
NDUFA1,COX5B,NDUFA5,SNCA,UQCR10,COX6A1,NDUFB2 |
2.648e-08 | -17.45 | Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins. | REACTOME pathways | R-HSA-163200 | 113 | 7 | 10285 | 30 |
NDUFA1,NDUFB2,NDUFA5,COX6A1,ETFB,COX5B,UQCR10 |
2.945e-08 | -17.34 | cellular respiration | biological process | GO:0045333 | 180 | 8 | 18204 | 50 |
NDUFA1,NDUFA5,UQCR10,COX5B,NDUFB2,COX6A1,SNCA,ETFB |
5.491e-08 | -16.72 | aerobic electron transport chain | biological process | GO:0019646 | 75 | 6 | 18204 | 50 |
NDUFA1,NDUFA5,UQCR10,COX6A1,COX5B,NDUFB2 |
6.107e-08 | -16.61 | respiratory chain complex | cellular component | GO:0098803 | 80 | 6 | 19108 | 50 |
NDUFB2,COX5B,UQCR10,NDUFA5,COX6A1,NDUFA1 |
7.626e-08 | -16.39 | mitochondrial respirasome | cellular component | GO:0005746 | 83 | 6 | 19108 | 50 |
COX6A1,NDUFA5,UQCR10,NDUFA1,NDUFB2,COX5B |
1.212e-07 | -15.93 | Alzheimer's disease | KEGG pathways | hsa05010 | 165 | 7 | 7161 | 19 |
COX6A1,NDUFB2,NDUFA1,SNCA,NDUFA5,COX5B,UQCR10 |
1.212e-07 | -15.93 | Alzheimer's disease | KEGG pathways | ko05010 | 165 | 7 | 7161 | 19 |
NDUFA1,COX6A1,NDUFA5,COX5B,NDUFB2,SNCA,UQCR10 |
1.326e-07 | -15.84 | respirasome | cellular component | GO:0070469 | 91 | 6 | 19108 | 50 |
NDUFA5,UQCR10,NDUFB2,COX6A1,NDUFA1,COX5B |
1.436e-07 | -15.76 | neuron projection | cellular component | GO:0043005 | 1331 | 16 | 19108 | 50 |
GAP43,RTN1,RUFY3,SYT1,EMX2,OLFM1,CALB2,CNTNAP2,CLU,NFIB,RELN,DNER,GNG3,SNCA,PDE4B,CCK |
1.589e-07 | -15.65 | aerobic respiration | biological process | GO:0009060 | 149 | 7 | 18204 | 50 |
UQCR10,NDUFA5,NDUFA1,NDUFB2,SNCA,COX5B,COX6A1 |
1.681e-07 | -15.60 | somatodendritic compartment | cellular component | GO:0036477 | 842 | 13 | 19108 | 50 |
DNER,GNG3,RELN,SNCA,PDE4B,RUFY3,RTN1,GAP43,CALB2,OLFM1,CLU,CNTNAP2,SEZ6L2 |
2.674e-07 | -15.13 | The citric acid (TCA) cycle and respiratory electron transport | REACTOME pathways | R-HSA-1428517 | 158 | 7 | 10285 | 30 |
COX5B,UQCR10,NDUFB2,NDUFA5,NDUFA1,ETFB,COX6A1 |
3.145e-07 | -14.97 | electron transfer activity | molecular function | GO:0009055 | 104 | 6 | 18094 | 48 |
NDUFA1,UQCR10,COX5B,NDUFB2,NDUFA5,ETFB |
3.340e-07 | -14.91 | oxidoreduction-driven active transmembrane transporter activity | molecular function | GO:0015453 | 55 | 5 | 18094 | 48 |
COX5B,UQCR10,NDUFB2,NDUFA1,NDUFA5 |
4.552e-07 | -14.60 | energy derivation by oxidation of organic compounds | biological process | GO:0015980 | 257 | 8 | 18204 | 50 |
SNCA,ETFB,COX6A1,NDUFB2,COX5B,UQCR10,NDUFA5,NDUFA1 |
1.011e-06 | -13.81 | Electron Transport Chain | WikiPathways | WP111 | 92 | 6 | 5310 | 21 |
COX5B,NDUFA5,NDUFA1,NDUFB2,COX6A1,UQCR10 |
1.357e-06 | -13.51 | Non-alcoholic fatty liver disease (NAFLD) | KEGG pathways | ko04932 | 145 | 6 | 7161 | 19 |
COX6A1,NDUFB2,NDUFA1,UQCR10,COX5B,NDUFA5 |
1.357e-06 | -13.51 | Non-alcoholic fatty liver disease (NAFLD) | KEGG pathways | hsa04932 | 145 | 6 | 7161 | 19 |
COX5B,NDUFA5,UQCR10,NDUFA1,NDUFB2,COX6A1 |
2.242e-06 | -13.01 | nervous system development | biological process | GO:0007399 | 2185 | 19 | 18204 | 50 |
RUFY3,CLU,CCK,CHD5,RELN,SPINT2,NRN1,CNTNAP2,OLFM1,CD9,CEND1,DNER,ACHE,SEZ6L2,EMX2,GAP43,NHLH2,RTN1,NFIB |
2.340e-06 | -12.97 | inner mitochondrial membrane protein complex | cellular component | GO:0098800 | 148 | 6 | 19108 | 50 |
NDUFB2,COX5B,UQCR10,NDUFA5,COX6A1,NDUFA1 |
2.810e-06 | -12.78 | primary active transmembrane transporter activity | molecular function | GO:0015399 | 151 | 6 | 18094 | 48 |
UQCR10,NDUFB2,COX5B,NDUFA1,ATP6V0B,NDUFA5 |
3.829e-06 | -12.47 | dendrite | cellular component | GO:0030425 | 620 | 10 | 19108 | 50 |
CNTNAP2,PDE4B,CLU,CALB2,GAP43,RUFY3,DNER,GNG3,RTN1,RELN |
3.940e-06 | -12.44 | dendritic tree | cellular component | GO:0097447 | 622 | 10 | 19108 | 50 |
CNTNAP2,CLU,PDE4B,GAP43,RELN,RTN1,DNER,RUFY3,GNG3,CALB2 |
4.388e-06 | -12.34 | cell projection | cellular component | GO:0042995 | 2398 | 19 | 19108 | 50 |
CLU,NFIB,SH3BGRL3,CNTNAP2,RUFY3,RTN1,GAP43,CALB2,OLFM1,SYT1,EMX2,THSD7A,PDE4B,NDRG4,CCK,DNER,GNG3,RELN,SNCA |
5.186e-06 | -12.17 | generation of precursor metabolites and energy | biological process | GO:0006091 | 356 | 8 | 18204 | 50 |
NDUFA5,UQCR10,NDUFA1,COX5B,NDUFB2,ETFB,SNCA,COX6A1 |
5.764e-06 | -12.06 | proton transmembrane transporter activity | molecular function | GO:0015078 | 171 | 6 | 18094 | 48 |
NDUFA5,NDUFA1,UQCR10,ATP6V0B,NDUFB2,COX5B |
5.814e-06 | -12.06 | axon | cellular component | GO:0030424 | 650 | 10 | 19108 | 50 |
NFIB,CNTNAP2,CCK,RUFY3,GAP43,CALB2,SYT1,EMX2,OLFM1,SNCA |
5.983e-06 | -12.03 | Huntington's disease | KEGG pathways | ko05016 | 187 | 6 | 7161 | 19 |
NDUFA1,COX5B,NDUFA5,UQCR10,COX6A1,NDUFB2 |
5.983e-06 | -12.03 | Huntington's disease | KEGG pathways | hsa05016 | 187 | 6 | 7161 | 19 |
UQCR10,COX5B,NDUFA5,NDUFA1,NDUFB2,COX6A1 |
8.161e-06 | -11.72 | cell differentiation | biological process | GO:0030154 | 3645 | 24 | 18204 | 50 |
CCK,RUFY3,TAGLN2,SPINT2,RELN,NDRG4,DNER,OLFM1,CNTNAP2,EMX2,NFIB,NHLH2,GAP43,ACHE,C1QTNF3,CLU,CHD5,CD9,CEND1,NRN1,IGFBP5,RTN1,SYT1,THSD7A |
8.282e-06 | -11.70 | cellular developmental process | biological process | GO:0048869 | 3648 | 24 | 18204 | 50 |
CHD5,C1QTNF3,CLU,IGFBP5,RTN1,SYT1,THSD7A,CD9,CEND1,NRN1,TAGLN2,RELN,SPINT2,NDRG4,CCK,RUFY3,EMX2,NFIB,NHLH2,GAP43,ACHE,DNER,OLFM1,CNTNAP2 |
9.205e-06 | -11.60 | neurogenesis | biological process | GO:0022008 | 1334 | 14 | 18204 | 50 |
CD9,CEND1,DNER,NRN1,CNTNAP2,EMX2,GAP43,RTN1,NHLH2,NFIB,CLU,CCK,RELN,CHD5 |
9.546e-06 | -11.56 | plasma membrane bounded cell projection | cellular component | GO:0120025 | 2285 | 18 | 19108 | 50 |
CCK,NDRG4,PDE4B,SNCA,RELN,GNG3,DNER,CNTNAP2,SH3BGRL3,CLU,NFIB,SYT1,EMX2,OLFM1,CALB2,GAP43,RTN1,RUFY3 |
1.212e-05 | -11.32 | cell body | cellular component | GO:0044297 | 556 | 9 | 19108 | 50 |
SNCA,OLFM1,GNG3,DNER,RUFY3,RTN1,GAP43,SEZ6L2,CNTNAP2 |
1.766e-05 | -10.94 | system development | biological process | GO:0048731 | 3533 | 23 | 18204 | 50 |
RELN,SPINT2,NDRG4,CCK,RUFY3,EMX2,NHLH2,NFIB,GAP43,ACHE,MAB21L1,DNER,CNTNAP2,OLFM1,CHD5,CLU,SEZ6L2,IGFBP5,RTN1,THSD7A,CD9,CEND1,NRN1 |
2.941e-05 | -10.43 | GPM6A (glycoprotein M6A) | protein interactions | 2823 | 143 | 5 | 19454 | 49 |
CALB2,SYT1,UQCR10,SNCA,NDRG4 |
3.627e-05 | -10.22 | neuronal cell body | cellular component | GO:0043025 | 489 | 8 | 19108 | 50 |
CNTNAP2,SEZ6L2,RTN1,DNER,RUFY3,GAP43,OLFM1,SNCA |
4.170e-05 | -10.08 | TEX101 (testis expressed 101) | protein interactions | 83639 | 255 | 6 | 19454 | 49 |
NDRG4,TAGLN2,CLU,CD9,DYNC1LI1,COX5B |
5.266e-05 | -9.85 | generation of neurons | biological process | GO:0048699 | 1158 | 12 | 18204 | 50 |
DNER,CEND1,CNTNAP2,NRN1,EMX2,NHLH2,RTN1,NFIB,GAP43,CCK,RELN,CHD5 |
5.910e-05 | -9.74 | COX7A2L (cytochrome c oxidase subunit 7A2 like) | protein interactions | 9167 | 84 | 4 | 19454 | 49 |
COX6A1,MGST3,UQCR10,COX5B |
6.099e-05 | -9.70 | lipoprotein particle receptor binding | molecular function | GO:0070325 | 29 | 3 | 18094 | 48 |
CLU,SYT1,RELN |
6.432e-05 | -9.65 | central nervous system development | biological process | GO:0007417 | 995 | 11 | 18204 | 50 |
DNER,CEND1,CNTNAP2,EMX2,RTN1,NFIB,NHLH2,GAP43,CLU,RELN,CHD5 |
7.549e-05 | -9.49 | mitochondrial protein-containing complex | cellular component | GO:0098798 | 273 | 6 | 19108 | 50 |
NDUFB2,COX5B,NDUFA5,UQCR10,COX6A1,NDUFA1 |
7.769e-05 | -9.46 | VLDLR (very low density lipoprotein receptor) | protein interactions | 7436 | 33 | 3 | 19454 | 49 |
CLU,RELN,SYT1 |
8.081e-05 | -9.42 | DGUOK (deoxyguanosine kinase) | protein interactions | 1716 | 91 | 4 | 19454 | 49 |
SYT1,SH3BGRL3,CALB2,SNCA |
8.215e-05 | -9.41 | active monoatomic ion transmembrane transporter activity | molecular function | GO:0022853 | 274 | 6 | 18094 | 48 |
ATP6V0B,NDUFA5,UQCR10,NDUFB2,COX5B,NDUFA1 |
8.804e-05 | -9.34 | oxidoreductase activity | molecular function | GO:0016491 | 709 | 9 | 18094 | 48 |
COX5B,NDUFB2,TXN,MGST3,COX6A1,NDUFA1,UQCR10,NDUFA5,SNCA |
9.896e-05 | -9.22 | NADH dehydrogenase (ubiquinone) activity | molecular function | GO:0008137 | 34 | 3 | 18094 | 48 |
NDUFA5,NDUFA1,NDUFB2 |
1.024e-04 | -9.19 | gliogenesis | biological process | GO:0042063 | 275 | 6 | 18204 | 50 |
CD9,CLU,DNER,GAP43,RELN,NFIB |
1.078e-04 | -9.14 | DNAAF2 (dynein axonemal assembly factor 2) | protein interactions | 55172 | 98 | 4 | 19454 | 49 |
SYT1,CALB2,NDRG4,SNCA |
1.133e-04 | -9.09 | cytochrome complex | cellular component | GO:0070069 | 36 | 3 | 19108 | 50 |
COX5B,COX6A1,UQCR10 |
1.153e-04 | -9.07 | multicellular organism development | biological process | GO:0007275 | 3957 | 23 | 18204 | 50 |
RTN1,IGFBP5,SEZ6L2,THSD7A,CEND1,CD9,NRN1,CHD5,CLU,NFIB,NHLH2,GAP43,EMX2,ACHE,MAB21L1,DNER,CNTNAP2,OLFM1,SPINT2,RELN,NDRG4,CCK,RUFY3 |
1.277e-04 | -8.97 | transmembrane transporter complex | cellular component | GO:1902495 | 434 | 7 | 19108 | 50 |
NDUFB2,CNTNAP2,UQCR10,NDUFA5,PDE4B,ATP6V0B,NDUFA1 |
1.349e-04 | -8.91 | neuron differentiation | biological process | GO:0030182 | 1081 | 11 | 18204 | 50 |
CEND1,CCK,CNTNAP2,NRN1,EMX2,NFIB,NHLH2,RTN1,RELN,GAP43,CHD5 |
1.389e-04 | -8.88 | TAGLN3 (transgelin 3) | protein interactions | 29114 | 40 | 3 | 19454 | 49 |
TAGLN2,SNCA,TXN |
1.662e-04 | -8.70 | mitochondrial electron transport, NADH to ubiquinone | biological process | GO:0006120 | 39 | 3 | 18204 | 50 |
NDUFB2,NDUFA1,NDUFA5 |
1.852e-04 | -8.59 | transporter complex | cellular component | GO:1990351 | 461 | 7 | 19108 | 50 |
NDUFB2,UQCR10,NDUFA5,CNTNAP2,PDE4B,ATP6V0B,NDUFA1 |
1.943e-04 | -8.55 | anatomical structure morphogenesis | biological process | GO:0009653 | 2225 | 16 | 18204 | 50 |
EMX2,IGFBP5,NFIB,GAP43,THSD7A,MAB21L1,CD9,CEND1,CNTNAP2,OLFM1,NRN1,RELN,SPINT2,NDRG4,CCK,CLU |
2.024e-04 | -8.51 | ADRB2 (adrenoceptor beta 2) | protein interactions | 154 | 340 | 6 | 19454 | 49 |
CD9,ETFB,RTN1,SNCA,NDUFA5,ATP6V0B |
2.048e-04 | -8.49 | positive regulation of vesicle fusion | biological process | GO:0031340 | 8 | 2 | 18204 | 50 |
SNCA,SYT1 |
2.070e-04 | -8.48 | mitochondrial respiratory chain complex I | cellular component | GO:0005747 | 44 | 3 | 19108 | 50 |
NDUFB2,NDUFA5,NDUFA1 |
2.070e-04 | -8.48 | respiratory chain complex I | cellular component | GO:0045271 | 44 | 3 | 19108 | 50 |
NDUFB2,NDUFA5,NDUFA1 |
2.070e-04 | -8.48 | NADH dehydrogenase complex | cellular component | GO:0030964 | 44 | 3 | 19108 | 50 |
NDUFA5,NDUFA1,NDUFB2 |
2.201e-04 | -8.42 | TMEM70 (transmembrane protein 70) | protein interactions | 54968 | 219 | 5 | 19454 | 49 |
RTN1,COX5B,NDUFA5,DUSP23,ETFB |
2.654e-04 | -8.23 | mitochondrial inner membrane | cellular component | GO:0005743 | 489 | 7 | 19108 | 50 |
COX6A1,NDUFA1,COX5B,NDUFA5,UQCR10,CLU,NDUFB2 |
2.813e-04 | -8.18 | oxidoreductase complex | cellular component | GO:1990204 | 121 | 4 | 19108 | 50 |
NDUFB2,NDUFA1,NDUFA5,UQCR10 |
2.872e-04 | -8.16 | NDUFA11 (NADH:ubiquinone oxidoreductase subunit A11) | protein interactions | 126328 | 51 | 3 | 19454 | 49 |
COX5B,NDUFA5,UQCR10 |
2.936e-04 | -8.13 | INS (insulin) | protein interactions | 3630 | 517 | 7 | 19454 | 49 |
NDUFA5,TXN,COX6A1,TAGLN2,CLU,SCG5,ETFB |
3.146e-04 | -8.06 | oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor | molecular function | GO:0016655 | 50 | 3 | 18094 | 48 |
NDUFB2,NDUFA1,NDUFA5 |
3.250e-04 | -8.03 | regulation of transport | biological process | GO:0051049 | 1621 | 13 | 18204 | 50 |
TXN,ACHE,SYT1,SNCA,OAZ1,PDE4B,NDRG4,SCG5,RELN,RUFY3,DYNC1LI1,CLU,C1QTNF3 |
3.251e-04 | -8.03 | synapse | cellular component | GO:0045202 | 1473 | 12 | 19108 | 50 |
SNCA,NRN1,GNG3,PDE4B,OLFM1,ACHE,SYT1,CALB2,GAP43,RTN1,CNTNAP2,CLU |
3.283e-04 | -8.02 | glial cell differentiation | biological process | GO:0010001 | 219 | 5 | 18204 | 50 |
RELN,CLU,GAP43,NFIB,DNER |
3.586e-04 | -7.93 | NUFIP1 (nuclear FMR1 interacting protein 1) | protein interactions | 26747 | 134 | 4 | 19454 | 49 |
CALB2,SYT1,NDRG4,SNCA |
3.689e-04 | -7.91 | C15orf48 (chromosome 15 open reading frame 48) | protein interactions | 84419 | 135 | 4 | 19454 | 49 |
NDUFA5,UQCR10,TXN,COX6A1 |
3.790e-04 | -7.88 | MIP (major intrinsic protein of lens fiber) | protein interactions | 4284 | 56 | 3 | 19454 | 49 |
MGST3,ATP6V0B,SYT1 |
3.939e-04 | -7.84 | limbic system development | biological process | GO:0021761 | 126 | 4 | 18204 | 50 |
CNTNAP2,EMX2,RELN,NHLH2 |
4.003e-04 | -7.82 | cellular response to epinephrine stimulus | biological process | GO:0071872 | 11 | 2 | 18204 | 50 |
PDE4B,SNCA |
4.036e-04 | -7.81 | LHFPL1 (LHFPL tetraspan subfamily member 1) | protein interactions | 340596 | 12 | 2 | 19454 | 49 |
THSD7A,IGFBP5 |
4.244e-04 | -7.76 | Complex I biogenesis | REACTOME pathways | R-HSA-6799198 | 51 | 3 | 10285 | 30 |
NDUFA5,NDUFB2,NDUFA1 |
4.500e-04 | -7.71 | CLPP (caseinolytic mitochondrial matrix peptidase proteolytic subunit) | protein interactions | 8192 | 555 | 7 | 19454 | 49 |
COX6A1,UQCR10,NDUFA5,SNCA,COX5B,ETFB,GAP43 |
4.626e-04 | -7.68 | NADH dehydrogenase complex assembly | biological process | GO:0010257 | 55 | 3 | 18204 | 50 |
NDUFB2,NDUFA5,NDUFA1 |
4.626e-04 | -7.68 | mitochondrial respiratory chain complex I assembly | biological process | GO:0032981 | 55 | 3 | 18204 | 50 |
NDUFB2,NDUFA5,NDUFA1 |
4.626e-04 | -7.68 | proton motive force-driven mitochondrial ATP synthesis | biological process | GO:0042776 | 55 | 3 | 18204 | 50 |
NDUFA5,NDUFA1,NDUFB2 |
4.633e-04 | -7.68 | HAX1 (HCLS1 associated protein X-1) | protein interactions | 10456 | 397 | 6 | 19454 | 49 |
SNCA,DUSP23,NDRG4,CLU,SYT1,CALB2 |
5.152e-04 | -7.57 | organelle inner membrane | cellular component | GO:0019866 | 546 | 7 | 19108 | 50 |
NDUFB2,CLU,NDUFA5,UQCR10,COX5B,NDUFA1,COX6A1 |
5.213e-04 | -7.56 | cell morphogenesis | biological process | GO:0000902 | 687 | 8 | 18204 | 50 |
CCK,CLU,CNTNAP2,NRN1,NFIB,SPINT2,RELN,GAP43 |
5.657e-04 | -7.48 | negative regulation of platelet-derived growth factor receptor signaling pathway | biological process | GO:0010642 | 13 | 2 | 18204 | 50 |
NDRG4,SNCA |
5.850e-04 | -7.44 | cellular component organization | biological process | GO:0016043 | 5636 | 27 | 18204 | 50 |
CHD5,DYNC1LI1,CLU,SEZ6L2,RTN1,SNCA,THSD7A,SYT1,CD9,NDUFA5,NRN1,SH3BGRL3,TAGLN2,SPINT2,RELN,DUSP23,CCK,RUFY3,NDUFA1,ATP6V0B,NFIB,GAP43,ACHE,DNER,NDUFB2,CNTNAP2,OLFM1 |
5.985e-04 | -7.42 | chromaffin granule | cellular component | GO:0042583 | 14 | 2 | 19108 | 50 |
SYT1,CLU |
6.187e-04 | -7.39 | neuron migration | biological process | GO:0001764 | 142 | 4 | 18204 | 50 |
EMX2,CCK,RELN,DNER |
6.366e-04 | -7.36 | DDIT4L (DNA damage inducible transcript 4 like) | protein interactions | 115265 | 156 | 4 | 19454 | 49 |
DUSP23,SCOC,TXN,SH3BGRL3 |
6.391e-04 | -7.36 | Cry1 (cryptochrome circadian regulator 1) | protein interactions | 12952 | 15 | 2 | 19454 | 49 |
TAGLN2,NFIB |
6.506e-04 | -7.34 | perikaryon | cellular component | GO:0043204 | 151 | 4 | 19108 | 50 |
GAP43,CNTNAP2,RUFY3,OLFM1 |
6.569e-04 | -7.33 | excitatory synapse | cellular component | GO:0060076 | 65 | 3 | 19108 | 50 |
SYT1,CALB2,PDE4B |
6.588e-04 | -7.33 | response to epinephrine | biological process | GO:0071871 | 14 | 2 | 18204 | 50 |
SNCA,PDE4B |
6.861e-04 | -7.28 | NADH dehydrogenase (ubiquinone) 1 alpha subcomplex | KEGG pathways | hsa_M00146 | 15 | 2 | 7161 | 19 |
NDUFA5,NDUFA1 |
6.861e-04 | -7.28 | NADH dehydrogenase (ubiquinone) 1 alpha subcomplex | KEGG pathways | M00146 | 15 | 2 | 7161 | 19 |
NDUFA5,NDUFA1 |
6.878e-04 | -7.28 | mitochondrial membrane | cellular component | GO:0031966 | 752 | 8 | 19108 | 50 |
COX6A1,NDUFA1,COX5B,MGST3,NDUFA5,UQCR10,CLU,NDUFB2 |
7.191e-04 | -7.24 | distal axon | cellular component | GO:0150034 | 273 | 5 | 19108 | 50 |
CALB2,SNCA,OLFM1,RUFY3,GAP43 |
7.220e-04 | -7.23 | proton motive force-driven ATP synthesis | biological process | GO:0015986 | 64 | 3 | 18204 | 50 |
NDUFB2,NDUFA1,NDUFA5 |
7.292e-04 | -7.22 | FABP7 (fatty acid binding protein 7) | protein interactions | 2173 | 16 | 2 | 19454 | 49 |
TAGLN2,SNCA |
7.292e-04 | -7.22 | CDC42EP2 (CDC42 effector protein 2) | protein interactions | 10435 | 16 | 2 | 19454 | 49 |
COX5B,SNCA |
7.359e-04 | -7.21 | brain development | biological process | GO:0007420 | 724 | 8 | 18204 | 50 |
EMX2,RELN,NHLH2,NFIB,RTN1,CHD5,CEND1,CNTNAP2 |
7.493e-04 | -7.20 | cell population proliferation | biological process | GO:0008283 | 726 | 8 | 18204 | 50 |
CD9,CLU,CNTNAP2,EMX2,IGFBP5,NFIB,MAB21L1,NDRG4 |
7.502e-04 | -7.20 | mast_cell_neoplasm | COSMIC cancer mutations | mast_cell_neoplasm | 248 | 5 | 16828 | 49 |
NFIB,SYT1,CNTNAP2,DNER,PDE4B |
7.502e-04 | -7.20 | haematopoietic_and_lymphoid_tissue-haematopoietic_neoplasm-mast_cell_neoplasm | COSMIC cancer mutations | haematopoietic_and_lymphoid_tissue-haematopoietic_neoplasm-mast_cell_neoplasm | 248 | 5 | 16828 | 49 |
NFIB,SYT1,CNTNAP2,DNER,PDE4B |
7.926e-04 | -7.14 | TOR1A (torsin family 1 member A) | protein interactions | 1861 | 72 | 3 | 19454 | 49 |
CLU,SNCA,MGST3 |
8.047e-04 | -7.13 | cell migration | biological process | GO:0016477 | 921 | 9 | 18204 | 50 |
NDRG4,EMX2,NHLH2,RELN,CD9,DNER,CEND1,PDE4B,CCK |
8.436e-04 | -7.08 | forebrain development | biological process | GO:0030900 | 408 | 6 | 18204 | 50 |
CNTNAP2,CHD5,EMX2,NHLH2,NFIB,RELN |
8.585e-04 | -7.06 | NDUFB1 (NADH:ubiquinone oxidoreductase subunit B1) | protein interactions | 4707 | 74 | 3 | 19454 | 49 |
NDUFA5,NDUFA1,NDUFB2 |
8.585e-04 | -7.06 | PPIL3 (peptidylprolyl isomerase like 3) | protein interactions | 53938 | 74 | 3 | 19454 | 49 |
COX5B,SNCA,TAGLN2 |
8.900e-04 | -7.02 | platelet alpha granule membrane | cellular component | GO:0031092 | 17 | 2 | 19108 | 50 |
SNCA,CD9 |
9.062e-04 | -7.01 | growth cone | cellular component | GO:0030426 | 165 | 4 | 19108 | 50 |
OLFM1,SNCA,RUFY3,GAP43 |
9.115e-04 | -7.00 | Cardiac muscle contraction | KEGG pathways | ko04260 | 74 | 3 | 7161 | 19 |
UQCR10,COX5B,COX6A1 |
9.115e-04 | -7.00 | Cardiac muscle contraction | KEGG pathways | hsa04260 | 74 | 3 | 7161 | 19 |
UQCR10,COX5B,COX6A1 |
9.267e-04 | -6.98 | COX3 (cytochrome c oxidase subunit III) | protein interactions | 4514 | 18 | 2 | 19454 | 49 |
COX6A1,SNCA |
9.487e-04 | -6.96 | mitochondrion | cellular component | GO:0005739 | 1659 | 12 | 19108 | 50 |
NDRG4,SNCA,COX6A1,CEND1,NDUFB2,CLU,NDUFA5,UQCR10,ETFB,COX5B,MGST3,NDUFA1 |
9.794e-04 | -6.93 | positive regulation of neurotransmitter secretion | biological process | GO:0001956 | 17 | 2 | 18204 | 50 |
SNCA,SYT1 |
9.794e-04 | -6.93 | cell migration in hindbrain | biological process | GO:0021535 | 17 | 2 | 18204 | 50 |
CEND1,NHLH2 |
9.986e-04 | -6.91 | MFF (mitochondrial fission factor) | protein interactions | 56947 | 176 | 4 | 19454 | 49 |
IGFBP5,MGST3,CEND1,ATP6V0B |
1.012e-03 | -6.90 | mitochondrial envelope | cellular component | GO:0005740 | 798 | 8 | 19108 | 50 |
COX6A1,NDUFA1,MGST3,COX5B,NDUFA5,UQCR10,CLU,NDUFB2 |
1.012e-03 | -6.90 | site of polarized growth | cellular component | GO:0030427 | 170 | 4 | 19108 | 50 |
RUFY3,GAP43,OLFM1,SNCA |
1.059e-03 | -6.85 | receptor internalization | biological process | GO:0031623 | 73 | 3 | 18204 | 50 |
ACHE,SNCA,CD9 |
1.082e-03 | -6.83 | active transmembrane transporter activity | molecular function | GO:0022804 | 444 | 6 | 18094 | 48 |
UQCR10,NDUFA1,NDUFA5,NDUFB2,COX5B,ATP6V0B |
1.112e-03 | -6.80 | cellular component organization or biogenesis | biological process | GO:0071840 | 5850 | 27 | 18204 | 50 |
DYNC1LI1,CLU,CHD5,NDUFA5,NRN1,CD9,THSD7A,SYT1,SEZ6L2,RTN1,SNCA,NDUFA1,RUFY3,DUSP23,CCK,TAGLN2,SH3BGRL3,RELN,SPINT2,OLFM1,CNTNAP2,DNER,NDUFB2,ACHE,ATP6V0B,NFIB,GAP43 |
1.115e-03 | -6.80 | NDUFA9 (NADH:ubiquinone oxidoreductase subunit A9) | protein interactions | 4704 | 313 | 5 | 19454 | 49 |
UQCR10,NDUFA5,NDUFA1,MGST3,NDUFB2 |
1.134e-03 | -6.78 | head development | biological process | GO:0060322 | 774 | 8 | 18204 | 50 |
CEND1,CNTNAP2,EMX2,RTN1,NHLH2,NFIB,RELN,CHD5 |
1.146e-03 | -6.77 | ATP biosynthetic process | biological process | GO:0006754 | 75 | 3 | 18204 | 50 |
NDUFA5,NDUFA1,NDUFB2 |
1.177e-03 | -6.74 | SURF1 (SURF1 cytochrome c oxidase assembly factor) | protein interactions | 6834 | 184 | 4 | 19454 | 49 |
COX5B,NDUFA5,COX6A1,ETFB |
1.203e-03 | -6.72 | oxidoreductase activity, acting on NAD(P)H | molecular function | GO:0016651 | 79 | 3 | 18094 | 48 |
NDUFA5,NDUFB2,NDUFA1 |
1.237e-03 | -6.69 | mitochondrial respiratory chain complex IV | cellular component | GO:0005751 | 20 | 2 | 19108 | 50 |
COX6A1,COX5B |
1.240e-03 | -6.69 | RAB27A (RAB27A, member RAS oncogene family) | protein interactions | 5873 | 84 | 3 | 19454 | 49 |
PCP4,SYT1,SH3BGRL3 |
1.266e-03 | -6.67 | TSPAN12 (tetraspanin 12) | protein interactions | 23554 | 21 | 2 | 19454 | 49 |
MGST3,IGFBP5 |
1.292e-03 | -6.65 | cell junction | cellular component | GO:0030054 | 2224 | 14 | 19108 | 50 |
GNG3,NRN1,SNCA,CD9,PDE4B,GAP43,RTN1,RUFY3,SYT1,ACHE,OLFM1,CALB2,CNTNAP2,CLU |
1.325e-03 | -6.63 | RMND1 (required for meiotic nuclear division 1 homolog) | protein interactions | 55005 | 190 | 4 | 19454 | 49 |
NDUFA5,COX5B,ETFB,COX6A1 |
1.359e-03 | -6.60 | Cytochrome c oxidase | KEGG pathways | hsa_M00154 | 21 | 2 | 7161 | 19 |
COX6A1,COX5B |
1.359e-03 | -6.60 | Cytochrome c oxidase | KEGG pathways | M00154 | 21 | 2 | 7161 | 19 |
COX5B,COX6A1 |
1.361e-03 | -6.60 | mitochondrial electron transport, cytochrome c to oxygen | biological process | GO:0006123 | 20 | 2 | 18204 | 50 |
COX6A1,COX5B |
1.372e-03 | -6.59 | membrane protein complex | cellular component | GO:0098796 | 1261 | 10 | 19108 | 50 |
COX6A1,ATP6V0B,GNG3,NDUFA1,COX5B,NDUFA5,UQCR10,CNTNAP2,PDE4B,NDUFB2 |
1.375e-03 | -6.59 | central nervous system neuron differentiation | biological process | GO:0021953 | 176 | 4 | 18204 | 50 |
CHD5,NFIB,CEND1,NHLH2 |
1.377e-03 | -6.59 | COX2 (cytochrome c oxidase subunit II) | protein interactions | 4513 | 192 | 4 | 19454 | 49 |
MGST3,COX6A1,COX5B,DUSP23 |
1.425e-03 | -6.55 | behavior | biological process | GO:0007610 | 619 | 7 | 18204 | 50 |
CEND1,CCK,CNTNAP2,NHLH2,SNCA,RELN,NDRG4 |
1.431e-03 | -6.55 | regulation of amide metabolic process | biological process | GO:0034248 | 81 | 3 | 18204 | 50 |
RTN1,CLU,SNCA |
1.503e-03 | -6.50 | haematopoietic_and_lymphoid_tissue-haematopoietic_neoplasm | COSMIC cancer mutations | haematopoietic_and_lymphoid_tissue-haematopoietic_neoplasm | 764 | 8 | 16828 | 49 |
PDE4B,NFIB,OLFM1,THSD7A,DNER,RELN,SYT1,CNTNAP2 |
1.542e-03 | -6.47 | NDUFA7 (NADH:ubiquinone oxidoreductase subunit A7) | protein interactions | 4701 | 198 | 4 | 19454 | 49 |
NDUFA5,COX6A1,NDUFA1,NDUFB2 |
1.587e-03 | -6.45 | UQCRC2 (ubiquinol-cytochrome c reductase core protein 2) | protein interactions | 7385 | 339 | 5 | 19454 | 49 |
COX5B,SNCA,NDUFA5,UQCR10,MGST3 |
1.639e-03 | -6.41 | respiratory chain complex IV | cellular component | GO:0045277 | 23 | 2 | 19108 | 50 |
COX5B,COX6A1 |
1.644e-03 | -6.41 | purine ribonucleoside triphosphate biosynthetic process | biological process | GO:0009206 | 85 | 3 | 18204 | 50 |
NDUFA1,NDUFA5,NDUFB2 |
1.656e-03 | -6.40 | GSTO2 (glutathione S-transferase omega 2) | protein interactions | 119391 | 24 | 2 | 19454 | 49 |
TXN,TAGLN2 |
1.698e-03 | -6.38 | TP53 Regulates Metabolic Genes | REACTOME pathways | R-HSA-5628897 | 82 | 3 | 10285 | 30 |
COX5B,COX6A1,TXN |
1.700e-03 | -6.38 | purine nucleoside triphosphate biosynthetic process | biological process | GO:0009145 | 86 | 3 | 18204 | 50 |
NDUFA1,NDUFA5,NDUFB2 |
1.742e-03 | -6.35 | platelet alpha granule | cellular component | GO:0031091 | 91 | 3 | 19108 | 50 |
CLU,SNCA,CD9 |
1.766e-03 | -6.34 | COX7C (cytochrome c oxidase subunit 7C) | protein interactions | 1350 | 95 | 3 | 19454 | 49 |
MGST3,COX6A1,COX5B |
1.803e-03 | -6.32 | positive regulation of neurotransmitter transport | biological process | GO:0051590 | 23 | 2 | 18204 | 50 |
SNCA,SYT1 |
1.803e-03 | -6.32 | regulation of vesicle fusion | biological process | GO:0031338 | 23 | 2 | 18204 | 50 |
SNCA,SYT1 |
1.832e-03 | -6.30 | low-density lipoprotein particle receptor binding | molecular function | GO:0050750 | 24 | 2 | 18094 | 48 |
SYT1,CLU |
1.875e-03 | -6.28 | COX6B1 (cytochrome c oxidase subunit 6B1) | protein interactions | 1340 | 97 | 3 | 19454 | 49 |
COX6A1,COX5B,UQCR10 |
1.881e-03 | -6.28 | central_nervous_system-brainstem-primitive_neuroectodermal_tumour-medulloblastoma-WNT_subtype | COSMIC cancer mutations | central_nervous_system-brainstem-primitive_neuroectodermal_tumour-medulloblastoma-WNT_subtype | 181 | 4 | 16828 | 49 |
CNTNAP2,SCOC,RELN,THSD7A |
1.913e-03 | -6.26 | human chr7q35-q36.1 | chromosome location | human chr7q35-q36.1 | 1 | 1 | 26134 | 50 |
CNTNAP2 |
1.913e-03 | -6.26 | human chr9p23-p22.3 | chromosome location | human chr9p23-p22.3 | 1 | 1 | 26134 | 50 |
NFIB |
1.913e-03 | -6.26 | human chr12q24.31|12q24.2 | chromosome location | human chr12q24.31|12q24.2 | 1 | 1 | 26134 | 50 |
COX6A1 |
1.919e-03 | -6.26 | WNT_subtype | COSMIC cancer mutations | WNT_subtype | 182 | 4 | 16828 | 49 |
THSD7A,SCOC,CNTNAP2,RELN |
1.927e-03 | -6.25 | developmental process | biological process | GO:0032502 | 5716 | 26 | 18204 | 50 |
CEND1,CD9,NRN1,IGFBP5,RTN1,SEZ6L2,THSD7A,SYT1,CLU,C1QTNF3,CHD5,DNER,OLFM1,CNTNAP2,NHLH2,NFIB,GAP43,EMX2,ACHE,MAB21L1,CCK,RUFY3,SPINT2,RELN,TAGLN2,NDRG4 |
1.944e-03 | -6.24 | endocytic vesicle membrane | cellular component | GO:0030666 | 203 | 4 | 19108 | 50 |
DYNC1LI1,ATP6V0B,CD9,SYT1 |
1.963e-03 | -6.23 | regulation of dopamine secretion | biological process | GO:0014059 | 24 | 2 | 18204 | 50 |
SNCA,SYT1 |
1.963e-03 | -6.23 | regulation of platelet-derived growth factor receptor signaling pathway | biological process | GO:0010640 | 24 | 2 | 18204 | 50 |
SNCA,NDRG4 |
1.966e-03 | -6.23 | positive regulation of transport | biological process | GO:0051050 | 844 | 8 | 18204 | 50 |
SYT1,ACHE,RELN,SNCA,OAZ1,RUFY3,CLU,C1QTNF3 |
1.979e-03 | -6.23 | UQCRC1 (ubiquinol-cytochrome c reductase core protein 1) | protein interactions | 7384 | 212 | 4 | 19454 | 49 |
COX6A1,MGST3,NDUFA5,UQCR10 |
1.998e-03 | -6.22 | ribonucleoside triphosphate biosynthetic process | biological process | GO:0009201 | 91 | 3 | 18204 | 50 |
NDUFA1,NDUFA5,NDUFB2 |
2.062e-03 | -6.18 | neuron projection morphogenesis | biological process | GO:0048812 | 486 | 6 | 18204 | 50 |
CCK,CNTNAP2,NRN1,NFIB,RELN,GAP43 |
2.083e-03 | -6.17 | TIMMDC1 (translocase of inner mitochondrial membrane domain containing 1) | protein interactions | 51300 | 215 | 4 | 19454 | 49 |
UQCR10,NDUFA5,COX5B,IGFBP5 |
2.095e-03 | -6.17 | SLC2A5 (solute carrier family 2 member 5) | protein interactions | 6518 | 27 | 2 | 19454 | 49 |
MGST3,ATP6V0B |
2.130e-03 | -6.15 | regulation of receptor recycling | biological process | GO:0001919 | 25 | 2 | 18204 | 50 |
SNCA,ACHE |
2.146e-03 | -6.14 | synapse organization | biological process | GO:0050808 | 333 | 5 | 18204 | 50 |
SEZ6L2,DNER,RELN,SNCA,ACHE |
2.168e-03 | -6.13 | human chr1q23.2 | chromosome location | human chr1q23.2 | 36 | 2 | 26134 | 50 |
TAGLN2,DUSP23 |
2.171e-03 | -6.13 | plasma membrane bounded cell projection morphogenesis | biological process | GO:0120039 | 491 | 6 | 18204 | 50 |
NRN1,CNTNAP2,RELN,GAP43,CCK,NFIB |
2.191e-03 | -6.12 | NDUFS3 (NADH:ubiquinone oxidoreductase core subunit S3) | protein interactions | 4722 | 365 | 5 | 19454 | 49 |
NDUFA5,UQCR10,MGST3,NDUFA1,COX6A1 |
2.284e-03 | -6.08 | cell projection morphogenesis | biological process | GO:0048858 | 496 | 6 | 18204 | 50 |
NFIB,CCK,RELN,GAP43,CNTNAP2,NRN1 |
2.304e-03 | -6.07 | negative regulation of neural precursor cell proliferation | biological process | GO:2000178 | 26 | 2 | 18204 | 50 |
SPINT2,CEND1 |
2.328e-03 | -6.06 | mitochondrial respiratory chain complex assembly | biological process | GO:0033108 | 96 | 3 | 18204 | 50 |
NDUFA1,NDUFA5,NDUFB2 |
2.416e-03 | -6.03 | HORMAD2 (HORMA domain containing 2) | protein interactions | 150280 | 29 | 2 | 19454 | 49 |
GAP43,NRN1 |
2.484e-03 | -6.00 | cell proliferation in forebrain | biological process | GO:0021846 | 27 | 2 | 18204 | 50 |
NFIB,EMX2 |
2.519e-03 | -5.98 | SLM2 (phosphatidylinositol 4,5-bisphosphate-binding protein) | protein interactions | 855680 | 1 | 1 | 19454 | 49 |
SNCA |
2.519e-03 | -5.98 | ABZ2 (aminodeoxychorismate lyase ABZ2) | protein interactions | 855333 | 1 | 1 | 19454 | 49 |
SNCA |
2.519e-03 | -5.98 | Dynll2 (dynein light chain LC8-type 2) | protein interactions | 68097 | 1 | 1 | 19454 | 49 |
SNCA |
2.519e-03 | -5.98 | ALB1 (Alb1p) | protein interactions | 853320 | 1 | 1 | 19454 | 49 |
SNCA |
2.519e-03 | -5.98 | YGR201C (uncharacterized protein) | protein interactions | 853115 | 1 | 1 | 19454 | 49 |
SNCA |
2.519e-03 | -5.98 | EMC4 (chaperone EMC4) | protein interactions | 852620 | 1 | 1 | 19454 | 49 |
SNCA |
2.519e-03 | -5.98 | Eno2 (enolase 2) | protein interactions | 24334 | 1 | 1 | 19454 | 49 |
SNCA |
2.519e-03 | -5.98 | PPZ1 (salt homeostasis regulator) | protein interactions | 854992 | 1 | 1 | 19454 | 49 |
SNCA |
2.519e-03 | -5.98 | YBR284W (metallo-dependent hydrolase superfamily protein) | protein interactions | 852587 | 1 | 1 | 19454 | 49 |
SNCA |
2.519e-03 | -5.98 | Ndufs4 (NADH:ubiquinone oxidoreductase core subunit S4) | protein interactions | 17993 | 1 | 1 | 19454 | 49 |
SNCA |
2.519e-03 | -5.98 | Cdc42ep2 (CDC42 effector protein 2) | protein interactions | 104252 | 1 | 1 | 19454 | 49 |
SNCA |
2.519e-03 | -5.98 | RHO2 (Rho family GTPase RHO2) | protein interactions | 855634 | 1 | 1 | 19454 | 49 |
SNCA |
2.519e-03 | -5.98 | Uqcrc1 (ubiquinol-cytochrome c reductase core protein 1) | protein interactions | 22273 | 1 | 1 | 19454 | 49 |
SNCA |
2.519e-03 | -5.98 | PHO13 (4-nitrophenylphosphatase) | protein interactions | 851362 | 1 | 1 | 19454 | 49 |
SNCA |
2.519e-03 | -5.98 | Gap43 (growth associated protein 43) | protein interactions | 29423 | 1 | 1 | 19454 | 49 |
SNCA |
2.519e-03 | -5.98 | Cox7a2l (cytochrome c oxidase subunit 7A2 like) | protein interactions | 20463 | 1 | 1 | 19454 | 49 |
SNCA |
2.519e-03 | -5.98 | SLG1 (Slg1p) | protein interactions | 854170 | 1 | 1 | 19454 | 49 |
SNCA |
2.519e-03 | -5.98 | PAM1 (Pam1p) | protein interactions | 851838 | 1 | 1 | 19454 | 49 |
SNCA |
2.519e-03 | -5.98 | SUV3 (ATP-dependent RNA helicase SUV3) | protein interactions | 856078 | 1 | 1 | 19454 | 49 |
SNCA |
2.519e-03 | -5.98 | YJL118W (uncharacterized protein) | protein interactions | 853323 | 1 | 1 | 19454 | 49 |
SNCA |
2.519e-03 | -5.98 | Ndufa2 (NADH:ubiquinone oxidoreductase subunit A2) | protein interactions | 17991 | 1 | 1 | 19454 | 49 |
SNCA |
2.519e-03 | -5.98 | Snca (synuclein alpha) | protein interactions | 29219 | 1 | 1 | 19454 | 49 |
SNCA |
2.519e-03 | -5.98 | Tubb3 (tubulin, beta 3 class III) | protein interactions | 246118 | 1 | 1 | 19454 | 49 |
SNCA |
2.519e-03 | -5.98 | Mgst3 (microsomal glutathione S-transferase 3) | protein interactions | 66447 | 1 | 1 | 19454 | 49 |
SNCA |
2.519e-03 | -5.98 | Fgr (FGR proto-oncogene, Src family tyrosine kinase) | protein interactions | 79113 | 1 | 1 | 19454 | 49 |
SNCA |
2.519e-03 | -5.98 | Pkm (pyruvate kinase M1/2) | protein interactions | 25630 | 1 | 1 | 19454 | 49 |
SNCA |
2.519e-03 | -5.98 | Ppia (peptidylprolyl isomerase A) | protein interactions | 25518 | 1 | 1 | 19454 | 49 |
SNCA |
2.519e-03 | -5.98 | Kcnab1 (potassium voltage-gated channel, shaker-related subfamily, beta member 1) | protein interactions | 16497 | 1 | 1 | 19454 | 49 |
SNCA |
2.519e-03 | -5.98 | HBS1 (ribosome dissociation factor GTPase HBS1) | protein interactions | 853959 | 1 | 1 | 19454 | 49 |
SNCA |
2.519e-03 | -5.98 | MIC19 (Mic19p) | protein interactions | 850563 | 1 | 1 | 19454 | 49 |
SNCA |
2.519e-03 | -5.98 | WAR1 (War1p) | protein interactions | 854899 | 1 | 1 | 19454 | 49 |
SNCA |
2.519e-03 | -5.98 | Ndufs1 (NADH:ubiquinone oxidoreductase core subunit S1) | protein interactions | 227197 | 1 | 1 | 19454 | 49 |
SNCA |
2.519e-03 | -5.98 | Uqcrc2 (ubiquinol cytochrome c reductase core protein 2) | protein interactions | 67003 | 1 | 1 | 19454 | 49 |
SNCA |
2.519e-03 | -5.98 | YCR050C (uncharacterized protein) | protein interactions | 850417 | 1 | 1 | 19454 | 49 |
SNCA |
2.519e-03 | -5.98 | Stx1a (syntaxin 1A (brain)) | protein interactions | 20907 | 1 | 1 | 19454 | 49 |
SNCA |
2.519e-03 | -5.98 | TCB1 (tricalbin) | protein interactions | 854253 | 1 | 1 | 19454 | 49 |
SNCA |
2.519e-03 | -5.98 | Opcml (opioid binding protein/cell adhesion molecule-like) | protein interactions | 330908 | 1 | 1 | 19454 | 49 |
SNCA |
2.519e-03 | -5.98 | DPP1 (bifunctional diacylglycerol diphosphate phosphatase/phosphatidate phosphatase) | protein interactions | 851878 | 1 | 1 | 19454 | 49 |
SNCA |
2.519e-03 | -5.98 | YPK9 (putative acid anhydride hydrolase) | protein interactions | 854466 | 1 | 1 | 19454 | 49 |
SNCA |
2.519e-03 | -5.98 | TNA1 (Tna1p) | protein interactions | 853175 | 1 | 1 | 19454 | 49 |
SNCA |
2.519e-03 | -5.98 | MTC3 (Mtc3p) | protein interactions | 852626 | 1 | 1 | 19454 | 49 |
SNCA |
2.519e-03 | -5.98 | SWR1 (chromatin-remodeling protein SWR1) | protein interactions | 851934 | 1 | 1 | 19454 | 49 |
SNCA |
2.519e-03 | -5.98 | Cox5b (cytochrome c oxidase subunit 5B) | protein interactions | 12859 | 1 | 1 | 19454 | 49 |
SNCA |
2.519e-03 | -5.98 | Uqcr10 (ubiquinol-cytochrome c reductase, complex III subunit X) | protein interactions | 66152 | 1 | 1 | 19454 | 49 |
SNCA |
2.519e-03 | -5.98 | NBP2 (Nbp2p) | protein interactions | 851740 | 1 | 1 | 19454 | 49 |
SNCA |
2.519e-03 | -5.98 | Mark1 (MAP/microtubule affinity regulating kinase 1) | protein interactions | 226778 | 1 | 1 | 19454 | 49 |
SNCA |
2.519e-03 | -5.98 | Csnk1g3 (casein kinase 1, gamma 3) | protein interactions | 64823 | 1 | 1 | 19454 | 49 |
SNCA |
2.519e-03 | -5.98 | ACTA1 (actin alpha 1, skeletal muscle) | protein interactions | 488984 | 1 | 1 | 19454 | 49 |
SNCA |
2.519e-03 | -5.98 | TCB3 (Tcb3p) | protein interactions | 854903 | 1 | 1 | 19454 | 49 |
SNCA |
2.519e-03 | -5.98 | Ndufb9 (NADH:ubiquinone oxidoreductase subunit B9) | protein interactions | 66218 | 1 | 1 | 19454 | 49 |
SNCA |
2.519e-03 | -5.98 | Caskin1 (CASK interacting protein 1) | protein interactions | 268932 | 1 | 1 | 19454 | 49 |
SNCA |
2.519e-03 | -5.98 | VPS60 (Vps60p) | protein interactions | 852097 | 1 | 1 | 19454 | 49 |
SNCA |
2.519e-03 | -5.98 | MID2 (Mid2p) | protein interactions | 851042 | 1 | 1 | 19454 | 49 |
SNCA |
2.519e-03 | -5.98 | Nme1 (NME/NM23 nucleoside diphosphate kinase 1) | protein interactions | 191575 | 1 | 1 | 19454 | 49 |
SNCA |
2.519e-03 | -5.98 | PEX2 (ubiquitin-protein ligase peroxin 2) | protein interactions | 853219 | 1 | 1 | 19454 | 49 |
SNCA |
2.519e-03 | -5.98 | Cox7a2 (cytochrome c oxidase subunit 7A2) | protein interactions | 12866 | 1 | 1 | 19454 | 49 |
SNCA |
2.519e-03 | -5.98 | Tomm22 (translocase of outer mitochondrial membrane 22) | protein interactions | 223696 | 1 | 1 | 19454 | 49 |
SNCA |
2.519e-03 | -5.98 | GTT1 (bifunctional glutathione transferase/peroxidase) | protein interactions | 854856 | 1 | 1 | 19454 | 49 |
SNCA |
2.519e-03 | -5.98 | Lactb (lactamase, beta) | protein interactions | 80907 | 1 | 1 | 19454 | 49 |
SNCA |
2.519e-03 | -5.98 | Ndufb5 (NADH:ubiquinone oxidoreductase subunit B5) | protein interactions | 66046 | 1 | 1 | 19454 | 49 |
SNCA |
2.519e-03 | -5.98 | Ndufa12 (NADH:ubiquinone oxidoreductase subunit A12) | protein interactions | 66414 | 1 | 1 | 19454 | 49 |
SNCA |
2.519e-03 | -5.98 | CRH1 (transglycosylase) | protein interactions | 853102 | 1 | 1 | 19454 | 49 |
SNCA |
2.519e-03 | -5.98 | Cntn1 (contactin 1) | protein interactions | 12805 | 1 | 1 | 19454 | 49 |
SNCA |
2.519e-03 | -5.98 | Atp6v0a1 (ATPase, H+ transporting, lysosomal V0 subunit A1) | protein interactions | 11975 | 1 | 1 | 19454 | 49 |
SNCA |
2.519e-03 | -5.98 | SLM1 (phosphatidylinositol 4,5-bisphosphate-binding protein) | protein interactions | 854701 | 1 | 1 | 19454 | 49 |
SNCA |
2.519e-03 | -5.98 | ARO1 (pentafunctional protein ARO1p) | protein interactions | 851705 | 1 | 1 | 19454 | 49 |
SNCA |
2.519e-03 | -5.98 | YKT6 (palmitoyltransferase YKT6) | protein interactions | 853638 | 1 | 1 | 19454 | 49 |
SNCA |
2.519e-03 | -5.98 | VPS24 (ESCRT-III subunit protein VPS24) | protein interactions | 853825 | 1 | 1 | 19454 | 49 |
SNCA |
2.519e-03 | -5.98 | Ntm (neurotrimin) | protein interactions | 235106 | 1 | 1 | 19454 | 49 |
SNCA |
2.519e-03 | -5.98 | Ndufb11 (NADH:ubiquinone oxidoreductase subunit B11) | protein interactions | 104130 | 1 | 1 | 19454 | 49 |
SNCA |
2.519e-03 | -5.98 | VPS28 (ESCRT-I subunit protein VPS28) | protein interactions | 856040 | 1 | 1 | 19454 | 49 |
SNCA |
2.519e-03 | -5.98 | COG6 (Golgi transport complex subunit COG6) | protein interactions | 855687 | 1 | 1 | 19454 | 49 |
SNCA |
2.519e-03 | -5.98 | RNY1 (ribonuclease T2) | protein interactions | 855980 | 1 | 1 | 19454 | 49 |
SNCA |
2.519e-03 | -5.98 | MEI4 (Mei4p) | protein interactions | 856768 | 1 | 1 | 19454 | 49 |
SNCA |
2.519e-03 | -5.98 | ALR1 (Mg(2+) transporter ALR1) | protein interactions | 853990 | 1 | 1 | 19454 | 49 |
SNCA |
2.519e-03 | -5.98 | SAP4 (Sap4p) | protein interactions | 852622 | 1 | 1 | 19454 | 49 |
SNCA |
2.519e-03 | -5.98 | THI7 (thiamine transporter THI7) | protein interactions | 850938 | 1 | 1 | 19454 | 49 |
SNCA |
2.519e-03 | -5.98 | YPF1 (aspartic endopeptidase) | protein interactions | 853761 | 1 | 1 | 19454 | 49 |
SNCA |
2.519e-03 | -5.98 | Ndufa8 (NADH:ubiquinone oxidoreductase subunit A8) | protein interactions | 68375 | 1 | 1 | 19454 | 49 |
SNCA |
2.519e-03 | -5.98 | Ndufb6 (NADH:ubiquinone oxidoreductase subunit B6) | protein interactions | 230075 | 1 | 1 | 19454 | 49 |
SNCA |
2.519e-03 | -5.98 | YBR013C (uncharacterized protein) | protein interactions | 852300 | 1 | 1 | 19454 | 49 |
SNCA |
2.519e-03 | -5.98 | Cox6a1 (cytochrome c oxidase subunit 6A1) | protein interactions | 12861 | 1 | 1 | 19454 | 49 |
SNCA |
2.519e-03 | -5.98 | Tmod2 (tropomodulin 2) | protein interactions | 50876 | 1 | 1 | 19454 | 49 |
SNCA |
2.519e-03 | -5.98 | GIP2 (Gip2p) | protein interactions | 856781 | 1 | 1 | 19454 | 49 |
SNCA |
2.519e-03 | -5.98 | Ndufb8 (NADH:ubiquinone oxidoreductase subunit B8) | protein interactions | 67264 | 1 | 1 | 19454 | 49 |
SNCA |
2.519e-03 | -5.98 | Vamp2 (vesicle-associated membrane protein 2) | protein interactions | 24803 | 1 | 1 | 19454 | 49 |
SNCA |
2.519e-03 | -5.98 | ND5 (NADH dehydrogenase subunit 5) | protein interactions | 17721 | 1 | 1 | 19454 | 49 |
SNCA |
2.519e-03 | -5.98 | MET32 (Met32p) | protein interactions | 851840 | 1 | 1 | 19454 | 49 |
SNCA |
2.519e-03 | -5.98 | Poldip3 (polymerase (DNA-directed), delta interacting protein 3) | protein interactions | 73826 | 1 | 1 | 19454 | 49 |
SNCA |
2.519e-03 | -5.98 | UQCRC1 (ubiquinol-cytochrome c reductase core protein 1) | protein interactions | 282393 | 1 | 1 | 19454 | 49 |
UQCR10 |
2.519e-03 | -5.98 | GTO1 (omega-class glutathione transferase) | protein interactions | 853058 | 1 | 1 | 19454 | 49 |
SNCA |
2.519e-03 | -5.98 | Myl12b (myosin, light chain 12B, regulatory) | protein interactions | 67938 | 1 | 1 | 19454 | 49 |
SNCA |
2.519e-03 | -5.98 | PDE2 (3',5'-cyclic-nucleotide phosphodiesterase PDE2) | protein interactions | 854542 | 1 | 1 | 19454 | 49 |
SNCA |
2.519e-03 | -5.98 | UQCRFS1 (ubiquinol-cytochrome c reductase, Rieske iron-sulfur polypeptide 1) | protein interactions | 287020 | 1 | 1 | 19454 | 49 |
UQCR10 |
2.519e-03 | -5.98 | Slc1a3 (solute carrier family 1 (glial high affinity glutamate transporter), member 3) | protein interactions | 20512 | 1 | 1 | 19454 | 49 |
SNCA |
2.519e-03 | -5.98 | YFR035C (uncharacterized protein) | protein interactions | 850595 | 1 | 1 | 19454 | 49 |
SNCA |
2.519e-03 | -5.98 | MAL31 (maltose permease) | protein interactions | 852601 | 1 | 1 | 19454 | 49 |
SNCA |
2.519e-03 | -5.98 | GIN4 (protein kinase GIN4) | protein interactions | 852119 | 1 | 1 | 19454 | 49 |
SNCA |
2.519e-03 | -5.98 | Ywhah (tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta) | protein interactions | 25576 | 1 | 1 | 19454 | 49 |
SNCA |
2.519e-03 | -5.98 | YPT10 (Rab family GTPase YPT10) | protein interactions | 852567 | 1 | 1 | 19454 | 49 |
SNCA |
2.519e-03 | -5.98 | SAC7 (GTPase-activating protein SAC7) | protein interactions | 851997 | 1 | 1 | 19454 | 49 |
SNCA |
2.519e-03 | -5.98 | UQCR11 (ubiquinol-cytochrome c reductase, complex III subunit XI) | protein interactions | 281570 | 1 | 1 | 19454 | 49 |
UQCR10 |
2.519e-03 | -5.98 | Ndufb4 (NADH:ubiquinone oxidoreductase subunit B4) | protein interactions | 68194 | 1 | 1 | 19454 | 49 |
SNCA |
2.519e-03 | -5.98 | RPN14 (Rpn14p) | protein interactions | 852880 | 1 | 1 | 19454 | 49 |
SNCA |
2.519e-03 | -5.98 | YCK2 (serine/threonine protein kinase YCK2) | protein interactions | 855568 | 1 | 1 | 19454 | 49 |
SNCA |
2.519e-03 | -5.98 | YCL042W (uncharacterized protein) | protein interactions | 850315 | 1 | 1 | 19454 | 49 |
SNCA |
2.519e-03 | -5.98 | POX1 (acyl-CoA oxidase) | protein interactions | 852667 | 1 | 1 | 19454 | 49 |
SNCA |
2.519e-03 | -5.98 | Dnajc5 (DnaJ heat shock protein family (Hsp40) member C5) | protein interactions | 13002 | 1 | 1 | 19454 | 49 |
SNCA |
2.519e-03 | -5.98 | Ndufa10 (NADH:ubiquinone oxidoreductase subunit A10) | protein interactions | 67273 | 1 | 1 | 19454 | 49 |
SNCA |
2.519e-03 | -5.98 | Pcp4 (Purkinje cell protein 4) | protein interactions | 25510 | 1 | 1 | 19454 | 49 |
SNCA |
2.519e-03 | -5.98 | CKI1 (bifunctional choline kinase/ethanolamine kinase CKI1) | protein interactions | 850824 | 1 | 1 | 19454 | 49 |
SNCA |
2.519e-03 | -5.98 | YBL086C (uncharacterized protein) | protein interactions | 852192 | 1 | 1 | 19454 | 49 |
SNCA |
2.519e-03 | -5.98 | PEX8 (Pex8p) | protein interactions | 852968 | 1 | 1 | 19454 | 49 |
SNCA |
2.519e-03 | -5.98 | Map7d1 (MAP7 domain containing 1) | protein interactions | 245877 | 1 | 1 | 19454 | 49 |
SNCA |
2.519e-03 | -5.98 | EFR3 (Efr3p) | protein interactions | 855252 | 1 | 1 | 19454 | 49 |
SNCA |
2.519e-03 | -5.98 | COX1 (cytochrome c oxidase subunit I) | protein interactions | 17708 | 1 | 1 | 19454 | 49 |
SNCA |
2.519e-03 | -5.98 | Kcnab2 (potassium voltage-gated channel, shaker-related subfamily, beta member 2) | protein interactions | 16498 | 1 | 1 | 19454 | 49 |
SNCA |
2.519e-03 | -5.98 | YPL199C (uncharacterized protein) | protein interactions | 855902 | 1 | 1 | 19454 | 49 |
SNCA |
2.519e-03 | -5.98 | Gk (glycerol kinase) | protein interactions | 14933 | 1 | 1 | 19454 | 49 |
SNCA |
2.519e-03 | -5.98 | ROM2 (Rho family guanine nucleotide exchange factor ROM2) | protein interactions | 851086 | 1 | 1 | 19454 | 49 |
SNCA |
2.519e-03 | -5.98 | Rps10 (ribosomal protein S10) | protein interactions | 67097 | 1 | 1 | 19454 | 49 |
SNCA |
2.519e-03 | -5.98 | Ndufs5 (NADH:ubiquinone oxidoreductase core subunit S5) | protein interactions | 595136 | 1 | 1 | 19454 | 49 |
SNCA |
2.519e-03 | -5.98 | APM4 (Apm4p) | protein interactions | 854092 | 1 | 1 | 19454 | 49 |
SNCA |
2.519e-03 | -5.98 | LRG1 (GTPase-activating protein LRG1) | protein interactions | 851358 | 1 | 1 | 19454 | 49 |
SNCA |
2.519e-03 | -5.98 | Icam5 (intercellular adhesion molecule 5, telencephalin) | protein interactions | 15898 | 1 | 1 | 19454 | 49 |
SNCA |
2.519e-03 | -5.98 | Ndufa11 (NADH:ubiquinone oxidoreductase subunit A11) | protein interactions | 69875 | 1 | 1 | 19454 | 49 |
SNCA |
2.519e-03 | -5.98 | Ndufa6 (NADH:ubiquinone oxidoreductase subunit A6) | protein interactions | 67130 | 1 | 1 | 19454 | 49 |
SNCA |
2.519e-03 | -5.98 | ND2 (NADH dehydrogenase subunit 2) | protein interactions | 17717 | 1 | 1 | 19454 | 49 |
SNCA |
2.519e-03 | -5.98 | RPL41A (ribosomal 60S subunit protein L41A) | protein interactions | 851344 | 1 | 1 | 19454 | 49 |
SNCA |
2.519e-03 | -5.98 | IST2 (Ist2p) | protein interactions | 852382 | 1 | 1 | 19454 | 49 |
SNCA |
2.519e-03 | -5.98 | Crmp1 (collapsin response mediator protein 1) | protein interactions | 25415 | 1 | 1 | 19454 | 49 |
SNCA |
2.519e-03 | -5.98 | PCA1 (cation-transporting P-type ATPase PCA1) | protein interactions | 852598 | 1 | 1 | 19454 | 49 |
SNCA |
2.519e-03 | -5.98 | Ndufb10 (NADH:ubiquinone oxidoreductase subunit B10) | protein interactions | 68342 | 1 | 1 | 19454 | 49 |
SNCA |
2.519e-03 | -5.98 | YJR154W (uncharacterized protein) | protein interactions | 853619 | 1 | 1 | 19454 | 49 |
SNCA |
2.519e-03 | -5.98 | ND1 (NADH dehydrogenase subunit 1) | protein interactions | 17716 | 1 | 1 | 19454 | 49 |
SNCA |
2.519e-03 | -5.98 | Ndufs7 (NADH:ubiquinone oxidoreductase core subunit S7) | protein interactions | 75406 | 1 | 1 | 19454 | 49 |
SNCA |
2.519e-03 | -5.98 | Thy1 (thymus cell antigen 1, theta) | protein interactions | 21838 | 1 | 1 | 19454 | 49 |
SNCA |
2.519e-03 | -5.98 | OSH2 (oxysterol-binding protein related protein OSH2) | protein interactions | 851543 | 1 | 1 | 19454 | 49 |
SNCA |
2.519e-03 | -5.98 | Ndufa5 (NADH:ubiquinone oxidoreductase subunit A5) | protein interactions | 68202 | 1 | 1 | 19454 | 49 |
SNCA |
2.519e-03 | -5.98 | FBXL5 (F-box and leucine rich repeat protein 5) | protein interactions | 103246333 | 1 | 1 | 19454 | 49 |
SNCA |
2.519e-03 | -5.98 | CSR2 (Csr2p) | protein interactions | 856142 | 1 | 1 | 19454 | 49 |
SNCA |
2.519e-03 | -5.98 | INO4 (Ino4p) | protein interactions | 854042 | 1 | 1 | 19454 | 49 |
SNCA |
2.519e-03 | -5.98 | Lsamp (limbic system-associated membrane protein) | protein interactions | 268890 | 1 | 1 | 19454 | 49 |
SNCA |
2.519e-03 | -5.98 | YCK1 (serine/threonine protein kinase YCK1) | protein interactions | 856537 | 1 | 1 | 19454 | 49 |
SNCA |
2.519e-03 | -5.98 | CRP1 (Crp1p) | protein interactions | 856551 | 1 | 1 | 19454 | 49 |
SNCA |
2.519e-03 | -5.98 | Hsc70-ps1 (heat shock cognate protein 70, pseudogene 1) | protein interactions | 494559 | 1 | 1 | 19454 | 49 |
SNCA |
2.519e-03 | -5.98 | YAT1 (carnitine O-acetyltransferase YAT1) | protein interactions | 851285 | 1 | 1 | 19454 | 49 |
SNCA |
2.519e-03 | -5.98 | Tomm40 (translocase of outer mitochondrial membrane 40) | protein interactions | 53333 | 1 | 1 | 19454 | 49 |
SNCA |
2.519e-03 | -5.98 | Mtch2 (mitochondrial carrier 2) | protein interactions | 56428 | 1 | 1 | 19454 | 49 |
SNCA |
2.519e-03 | -5.98 | Mif (macrophage migration inhibitory factor) | protein interactions | 81683 | 1 | 1 | 19454 | 49 |
SNCA |
2.519e-03 | -5.98 | SKG3 (Skg3p) | protein interactions | 850884 | 1 | 1 | 19454 | 49 |
SNCA |
2.519e-03 | -5.98 | Atp5pd (ATP synthase peripheral stalk subunit d) | protein interactions | 71679 | 1 | 1 | 19454 | 49 |
SNCA |
2.519e-03 | -5.98 | NIT2 (putative hydrolase) | protein interactions | 853316 | 1 | 1 | 19454 | 49 |
SNCA |
2.519e-03 | -5.98 | ND4 (NADH dehydrogenase subunit 4) | protein interactions | 17719 | 1 | 1 | 19454 | 49 |
SNCA |
2.519e-03 | -5.98 | RQT4 (Rqt4p) | protein interactions | 853893 | 1 | 1 | 19454 | 49 |
SNCA |
2.519e-03 | -5.98 | Uqcrfs1 (ubiquinol-cytochrome c reductase, Rieske iron-sulfur polypeptide 1) | protein interactions | 66694 | 1 | 1 | 19454 | 49 |
SNCA |
2.519e-03 | -5.98 | BOI1 (Boi1p) | protein interactions | 852193 | 1 | 1 | 19454 | 49 |
SNCA |
2.519e-03 | -5.98 | MDG1 (Mdg1p) | protein interactions | 855548 | 1 | 1 | 19454 | 49 |
SNCA |
2.519e-03 | -5.98 | Lrp8 (low density lipoprotein receptor-related protein 8, apolipoprotein e receptor) | protein interactions | 16975 | 1 | 1 | 19454 | 49 |
RELN |
2.519e-03 | -5.98 | Cyc1 (cytochrome c-1) | protein interactions | 66445 | 1 | 1 | 19454 | 49 |
SNCA |
2.519e-03 | -5.98 | Ndufb7 (NADH:ubiquinone oxidoreductase subunit B7) | protein interactions | 66916 | 1 | 1 | 19454 | 49 |
SNCA |
2.519e-03 | -5.98 | Uqcrb (ubiquinol-cytochrome c reductase binding protein) | protein interactions | 67530 | 1 | 1 | 19454 | 49 |
SNCA |
2.519e-03 | -5.98 | Ndufc2 (NADH:ubiquinone oxidoreductase subunit C2) | protein interactions | 68197 | 1 | 1 | 19454 | 49 |
SNCA |
2.519e-03 | -5.98 | Ndufs8 (NADH:ubiquinone oxidoreductase core subunit S8) | protein interactions | 225887 | 1 | 1 | 19454 | 49 |
SNCA |
2.519e-03 | -5.98 | Ctnna2 (catenin alpha 2) | protein interactions | 12386 | 1 | 1 | 19454 | 49 |
SNCA |
2.519e-03 | -5.98 | RAS1 (Ras family GTPase RAS1) | protein interactions | 854268 | 1 | 1 | 19454 | 49 |
SNCA |
2.519e-03 | -5.98 | UBC8 (E2 ubiquitin-conjugating protein UBC8) | protein interactions | 856704 | 1 | 1 | 19454 | 49 |
SNCA |
2.519e-03 | -5.98 | BUD2 (GTPase-activating protein BUD2) | protein interactions | 853770 | 1 | 1 | 19454 | 49 |
SNCA |
2.519e-03 | -5.98 | MTC2 (Mtc2p) | protein interactions | 853763 | 1 | 1 | 19454 | 49 |
SNCA |
2.519e-03 | -5.98 | Ank2 (ankyrin 2, brain) | protein interactions | 109676 | 1 | 1 | 19454 | 49 |
SNCA |
2.519e-03 | -5.98 | OSH3 (oxysterol-binding protein related protein OSH3) | protein interactions | 856472 | 1 | 1 | 19454 | 49 |
SNCA |
2.519e-03 | -5.98 | Agap2 (ArfGAP with GTPase domain, ankyrin repeat and PH domain 2) | protein interactions | 216439 | 1 | 1 | 19454 | 49 |
SNCA |
2.519e-03 | -5.98 | Txnip (thioredoxin interacting protein) | protein interactions | 56338 | 1 | 1 | 19454 | 49 |
TXN |
2.519e-03 | -5.98 | ARL3 (Arf family GTPase ARL3) | protein interactions | 856056 | 1 | 1 | 19454 | 49 |
SNCA |
2.519e-03 | -5.98 | Atp6v1b2 (ATPase H+ transporting V1 subunit B2) | protein interactions | 117596 | 1 | 1 | 19454 | 49 |
SNCA |
2.519e-03 | -5.98 | Cox6b1 (cytochrome c oxidase, subunit 6B1) | protein interactions | 110323 | 1 | 1 | 19454 | 49 |
SNCA |
2.519e-03 | -5.98 | Slc25a4 (solute carrier family 25 member 4) | protein interactions | 85333 | 1 | 1 | 19454 | 49 |
SNCA |
2.519e-03 | -5.98 | Uqcrq (ubiquinol-cytochrome c reductase, complex III subunit VII) | protein interactions | 22272 | 1 | 1 | 19454 | 49 |
SNCA |
2.519e-03 | -5.98 | FUN26 (nucleoside transmembrane transporter FUN26) | protein interactions | 851211 | 1 | 1 | 19454 | 49 |
SNCA |
2.519e-03 | -5.98 | PTK2 (protein kinase PTK2) | protein interactions | 853522 | 1 | 1 | 19454 | 49 |
SNCA |
2.519e-03 | -5.98 | YGL262W (uncharacterized protein) | protein interactions | 852629 | 1 | 1 | 19454 | 49 |
SNCA |
2.519e-03 | -5.98 | TUS1 (Rho family guanine nucleotide exchange factor TUS1) | protein interactions | 851145 | 1 | 1 | 19454 | 49 |
SNCA |
2.519e-03 | -5.98 | SPF1 (ion-transporting P-type ATPase SPF1) | protein interactions | 856681 | 1 | 1 | 19454 | 49 |
SNCA |
2.519e-03 | -5.98 | AGRN (agrin) | protein interactions | 396538 | 1 | 1 | 19454 | 49 |
SNCA |
2.519e-03 | -5.98 | Map1lc3a (microtubule-associated protein 1 light chain 3 alpha) | protein interactions | 66734 | 1 | 1 | 19454 | 49 |
SNCA |
2.519e-03 | -5.98 | Cd47 (CD47 antigen (Rh-related antigen, integrin-associated signal transducer)) | protein interactions | 16423 | 1 | 1 | 19454 | 49 |
SNCA |
2.519e-03 | -5.98 | Ndufb3 (NADH:ubiquinone oxidoreductase subunit B3) | protein interactions | 66495 | 1 | 1 | 19454 | 49 |
SNCA |
2.519e-03 | -5.98 | AIM46 (Aim46p) | protein interactions | 856606 | 1 | 1 | 19454 | 49 |
SNCA |
2.519e-03 | -5.98 | Atp5mk (ATP synthase membrane subunit k) | protein interactions | 66477 | 1 | 1 | 19454 | 49 |
SNCA |
2.519e-03 | -5.98 | BUD3 (Bud3p) | protein interactions | 850345 | 1 | 1 | 19454 | 49 |
SNCA |
2.519e-03 | -5.98 | NAT3 (peptide alpha-N-acetyltransferase complex B subunit NAT3) | protein interactions | 856249 | 1 | 1 | 19454 | 49 |
SNCA |
2.541e-03 | -5.98 | nucleoside triphosphate biosynthetic process | biological process | GO:0009142 | 99 | 3 | 18204 | 50 |
NDUFB2,NDUFA5,NDUFA1 |
2.590e-03 | -5.96 | neuron to neuron synapse | cellular component | GO:0098984 | 365 | 5 | 19108 | 50 |
SYT1,GAP43,PDE4B,RTN1,GNG3 |
2.614e-03 | -5.95 | MCTS1 (MCTS1 re-initiation and release factor) | protein interactions | 28985 | 109 | 3 | 19454 | 49 |
ISOC1,SNCA,SYT1 |
2.617e-03 | -5.95 | perinuclear endoplasmic reticulum lumen | cellular component | GO:0099020 | 1 | 1 | 19108 | 50 |
CLU |
2.617e-03 | -5.95 | reelin complex | cellular component | GO:0110157 | 1 | 1 | 19108 | 50 |
RELN |
2.626e-03 | -5.94 | Cytochrome b-c1 complex subunit 9 | gene3d domains | 1.20.5.260 | 1 | 1 | 14470 | 38 |
UQCR10 |
2.626e-03 | -5.94 | Cytochrome c oxidase, subunit Vb | gene3d domains | 2.60.11.10 | 1 | 1 | 14470 | 38 |
COX5B |
2.643e-03 | -5.94 | regulation of localization | biological process | GO:0032879 | 2028 | 13 | 18204 | 50 |
OAZ1,PDE4B,ACHE,SYT1,TXN,SNCA,RUFY3,C1QTNF3,DYNC1LI1,CLU,SCG5,NDRG4,RELN |
2.646e-03 | -5.93 | DNER_C | interpro domains | IPR045769 | 1 | 1 | 18521 | 49 |
DNER |
2.646e-03 | -5.93 | IGFBP-5 | interpro domains | IPR012213 | 1 | 1 | 18521 | 49 |
IGFBP5 |
2.646e-03 | -5.93 | Neuromodulin_C | interpro domains | IPR017454 | 1 | 1 | 18521 | 49 |
GAP43 |
2.646e-03 | -5.93 | TSTD1_mml | interpro domains | IPR042457 | 1 | 1 | 18521 | 49 |
TSTD1 |
2.646e-03 | -5.93 | QCR9 | interpro domains | IPR008027 | 1 | 1 | 18521 | 49 |
UQCR10 |
2.646e-03 | -5.93 | Synuclein_alpha | interpro domains | IPR002460 | 1 | 1 | 18521 | 49 |
SNCA |
2.646e-03 | -5.93 | Neuromodulin_palmitoyl_site | interpro domains | IPR018243 | 1 | 1 | 18521 | 49 |
GAP43 |
2.646e-03 | -5.93 | MLLT11_fam | interpro domains | IPR026778 | 1 | 1 | 18521 | 49 |
MLLT11 |
2.646e-03 | -5.93 | ET-Flavoprotein_bsu_CS | interpro domains | IPR000049 | 1 | 1 | 18521 | 49 |
ETFB |
2.646e-03 | -5.93 | Reelin | interpro domains | IPR034968 | 1 | 1 | 18521 | 49 |
RELN |
2.646e-03 | -5.93 | CCK-like | interpro domains | IPR015499 | 1 | 1 | 18521 | 49 |
CCK |
2.646e-03 | -5.93 | Secretogranin_V | interpro domains | IPR007945 | 1 | 1 | 18521 | 49 |
SCG5 |
2.646e-03 | -5.93 | NDUFB2_animal | interpro domains | IPR026627 | 1 | 1 | 18521 | 49 |
NDUFB2 |
2.646e-03 | -5.93 | RUN_RUFY3 | interpro domains | IPR047334 | 1 | 1 | 18521 | 49 |
RUFY3 |
2.646e-03 | -5.93 | CALB2 | interpro domains | IPR029646 | 1 | 1 | 18521 | 49 |
CALB2 |
2.646e-03 | -5.93 | Clusterin | interpro domains | IPR016016 | 1 | 1 | 18521 | 49 |
CLU |
2.646e-03 | -5.93 | NDUFA5 | interpro domains | IPR006806 | 1 | 1 | 18521 | 49 |
NDUFA5 |
2.646e-03 | -5.93 | DEXHc_CHD5 | interpro domains | IPR028727 | 1 | 1 | 18521 | 49 |
CHD5 |
2.646e-03 | -5.93 | Neuromodulin | interpro domains | IPR001422 | 1 | 1 | 18521 | 49 |
GAP43 |
2.646e-03 | -5.93 | Neuromodulin_gap-junction_N | interpro domains | IPR018947 | 1 | 1 | 18521 | 49 |
GAP43 |
2.646e-03 | -5.93 | ETF_b | interpro domains | IPR012255 | 1 | 1 | 18521 | 49 |
ETFB |
2.646e-03 | -5.93 | Clusterin_CS | interpro domains | IPR033986 | 1 | 1 | 18521 | 49 |
CLU |
2.646e-03 | -5.93 | ETF_beta_N | interpro domains | IPR033948 | 1 | 1 | 18521 | 49 |
ETFB |
2.646e-03 | -5.93 | Reelin_subrepeat-B | interpro domains | IPR049419 | 1 | 1 | 18521 | 49 |
RELN |
2.646e-03 | -5.93 | SCOC | interpro domains | IPR019357 | 1 | 1 | 18521 | 49 |
SCOC |
2.646e-03 | -5.93 | Cyt_c_oxidase_su5b_sf | interpro domains | IPR036972 | 1 | 1 | 18521 | 49 |
COX5B |
2.646e-03 | -5.93 | Cend1 | interpro domains | IPR020162 | 1 | 1 | 18521 | 49 |
CEND1 |
2.646e-03 | -5.93 | CD9_LEL | interpro domains | IPR042055 | 1 | 1 | 18521 | 49 |
CD9 |
2.646e-03 | -5.93 | Cyt_c_oxidase_su5b | interpro domains | IPR002124 | 1 | 1 | 18521 | 49 |
COX5B |
2.646e-03 | -5.93 | NADH_Ub_cplx-1_asu_su-1 | interpro domains | IPR017384 | 1 | 1 | 18521 | 49 |
NDUFA1 |
2.646e-03 | -5.93 | Neuromodulin_P_site | interpro domains | IPR033137 | 1 | 1 | 18521 | 49 |
GAP43 |
2.646e-03 | -5.93 | QCR9_sf | interpro domains | IPR036656 | 1 | 1 | 18521 | 49 |
UQCR10 |
2.653e-03 | -5.93 | phospholipase D inhibitor activity | molecular function | GO:0060961 | 1 | 1 | 18094 | 48 |
SNCA |
2.653e-03 | -5.93 | thiosulfate-thiol sulfurtransferase activity | molecular function | GO:0050337 | 1 | 1 | 18094 | 48 |
TSTD1 |
2.670e-03 | -5.93 | glial cell proliferation | biological process | GO:0014009 | 28 | 2 | 18204 | 50 |
CLU,NFIB |
2.673e-03 | -5.92 | glutathione transferase activity | molecular function | GO:0004364 | 29 | 2 | 18094 | 48 |
SH3BGRL3,MGST3 |
2.708e-03 | -5.91 | COX5B_1 | prosite domains | PS00848 | 1 | 1 | 12186 | 33 |
COX5B |
2.708e-03 | -5.91 | NEUROMODULIN_2 | prosite domains | PS00413 | 1 | 1 | 12186 | 33 |
GAP43 |
2.708e-03 | -5.91 | NEUROMODULIN_1 | prosite domains | PS00412 | 1 | 1 | 12186 | 33 |
GAP43 |
2.708e-03 | -5.91 | CLUSTERIN_2 | prosite domains | PS00493 | 1 | 1 | 12186 | 33 |
CLU |
2.708e-03 | -5.91 | CLUSTERIN_1 | prosite domains | PS00492 | 1 | 1 | 12186 | 33 |
CLU |
2.708e-03 | -5.91 | COX5B_2 | prosite domains | PS51359 | 1 | 1 | 12186 | 33 |
COX5B |
2.708e-03 | -5.91 | ETF_BETA | prosite domains | PS01065 | 1 | 1 | 12186 | 33 |
ETFB |
2.747e-03 | -5.90 | negative regulation of dopamine uptake involved in synaptic transmission | biological process | GO:0051585 | 1 | 1 | 18204 | 50 |
SNCA |
2.747e-03 | -5.90 | negative regulation of norepinephrine uptake | biological process | GO:0051622 | 1 | 1 | 18204 | 50 |
SNCA |
2.747e-03 | -5.90 | regulation of motor neuron migration | biological process | GO:1905483 | 1 | 1 | 18204 | 50 |
RELN |
2.747e-03 | -5.90 | positive regulation of neurofibrillary tangle assembly | biological process | GO:1902998 | 1 | 1 | 18204 | 50 |
CLU |
2.747e-03 | -5.90 | positive regulation of SNARE complex assembly | biological process | GO:0035543 | 1 | 1 | 18204 | 50 |
SNCA |
2.747e-03 | -5.90 | regulation of lateral motor column neuron migration | biological process | GO:1902076 | 1 | 1 | 18204 | 50 |
RELN |
2.747e-03 | -5.90 | positive regulation of lateral motor column neuron migration | biological process | GO:1902078 | 1 | 1 | 18204 | 50 |
RELN |
2.747e-03 | -5.90 | fast, calcium ion-dependent exocytosis of neurotransmitter | biological process | GO:0098746 | 1 | 1 | 18204 | 50 |
SYT1 |
2.747e-03 | -5.90 | radial glia guided migration of cerebellar granule cell | biological process | GO:0021933 | 1 | 1 | 18204 | 50 |
CEND1 |
2.747e-03 | -5.90 | positive regulation of motor neuron migration | biological process | GO:1905485 | 1 | 1 | 18204 | 50 |
RELN |
2.747e-03 | -5.90 | regulation of neuronal signal transduction | biological process | GO:1902847 | 1 | 1 | 18204 | 50 |
CLU |
2.747e-03 | -5.90 | regulation of glutathione peroxidase activity | biological process | GO:1903282 | 1 | 1 | 18204 | 50 |
SNCA |
2.747e-03 | -5.90 | negative regulation of epithelial cell proliferation involved in lung morphogenesis | biological process | GO:2000795 | 1 | 1 | 18204 | 50 |
NFIB |
2.747e-03 | -5.90 | positive regulation of calcium ion-dependent exocytosis of neurotransmitter | biological process | GO:1903235 | 1 | 1 | 18204 | 50 |
SYT1 |
2.747e-03 | -5.90 | negative regulation of synaptic transmission, cholinergic | biological process | GO:0032223 | 1 | 1 | 18204 | 50 |
ACHE |
2.747e-03 | -5.90 | positive regulation of glutathione peroxidase activity | biological process | GO:1903284 | 1 | 1 | 18204 | 50 |
SNCA |
2.747e-03 | -5.90 | synchronous neurotransmitter secretion | biological process | GO:0071911 | 1 | 1 | 18204 | 50 |
SYT1 |
2.747e-03 | -5.90 | negative regulation of skeletal muscle hypertrophy | biological process | GO:1904205 | 1 | 1 | 18204 | 50 |
IGFBP5 |
2.747e-03 | -5.90 | negative regulation of catecholamine uptake involved in synaptic transmission | biological process | GO:0051945 | 1 | 1 | 18204 | 50 |
SNCA |
2.747e-03 | -5.90 | lung ciliated cell differentiation | biological process | GO:0061141 | 1 | 1 | 18204 | 50 |
NFIB |
2.747e-03 | -5.90 | cerebellar granular layer maturation | biological process | GO:0021686 | 1 | 1 | 18204 | 50 |
CEND1 |
2.754e-03 | -5.89 | Secretogranin_V | pfam domains | PF05281 | 1 | 1 | 17795 | 49 |
SCG5 |
2.754e-03 | -5.89 | MWFE | pfam domains | PF15879 | 1 | 1 | 17795 | 49 |
NDUFA1 |
2.754e-03 | -5.89 | Reelin_subrepeat-B | pfam domains | PF21471 | 1 | 1 | 17795 | 49 |
RELN |
2.754e-03 | -5.89 | ETC_C1_NDUFA5 | pfam domains | PF04716 | 1 | 1 | 17795 | 49 |
NDUFA5 |
2.754e-03 | -5.89 | NADH_B2 | pfam domains | PF14813 | 1 | 1 | 17795 | 49 |
NDUFB2 |
2.754e-03 | -5.89 | DNER_C | pfam domains | PF19330 | 1 | 1 | 17795 | 49 |
DNER |
2.754e-03 | -5.89 | COX5B | pfam domains | PF01215 | 1 | 1 | 17795 | 49 |
COX5B |
2.754e-03 | -5.89 | Neuromodulin_N | pfam domains | PF10580 | 1 | 1 | 17795 | 49 |
GAP43 |
2.754e-03 | -5.89 | DUF2205 | pfam domains | PF10224 | 1 | 1 | 17795 | 49 |
SCOC |
2.754e-03 | -5.89 | UCR_UQCRX_QCR9 | pfam domains | PF05365 | 1 | 1 | 17795 | 49 |
UQCR10 |
2.754e-03 | -5.89 | CEND1 | pfam domains | PF15677 | 1 | 1 | 17795 | 49 |
CEND1 |
2.754e-03 | -5.89 | Neuromodulin | pfam domains | PF06614 | 1 | 1 | 17795 | 49 |
GAP43 |
2.777e-03 | -5.89 | cell motility | biological process | GO:0048870 | 1101 | 9 | 18204 | 50 |
CD9,PDE4B,CCK,CEND1,DNER,NDRG4,EMX2,RELN,NHLH2 |
2.814e-03 | -5.87 | anatomical structure development | biological process | GO:0048856 | 5207 | 24 | 18204 | 50 |
CEND1,CD9,NRN1,RTN1,IGFBP5,SEZ6L2,THSD7A,CLU,CHD5,DNER,CNTNAP2,OLFM1,GAP43,NFIB,NHLH2,EMX2,MAB21L1,ACHE,CCK,RUFY3,RELN,SPINT2,TAGLN2,NDRG4 |
2.863e-03 | -5.86 | negative regulation of amyloid-beta formation | biological process | GO:1902430 | 29 | 2 | 18204 | 50 |
RTN1,CLU |
2.870e-03 | -5.85 | IGFBPFAMILY5 | prints domains | PR01981 | 1 | 1 | 5227 | 15 |
IGFBP5 |
2.870e-03 | -5.85 | ASYNUCLEIN | prints domains | PR01212 | 1 | 1 | 5227 | 15 |
SNCA |
2.870e-03 | -5.85 | NEUROMODULIN | prints domains | PR00215 | 1 | 1 | 5227 | 15 |
GAP43 |
2.937e-03 | -5.83 | RUFY2 (RUN and FYVE domain containing 2) | protein interactions | 55680 | 32 | 2 | 19454 | 49 |
DUSP23,RUFY3 |
2.968e-03 | -5.82 | PSAP (prosaposin) | protein interactions | 5660 | 114 | 3 | 19454 | 49 |
TXN,SH3BGRL3,SNCA |
3.198e-03 | -5.75 | cytoplasm | cellular component | GO:0005737 | 12081 | 41 | 19108 | 50 |
CD9,SNCA,ATP6V0B,MLLT11,COX6A1,TSTD1,CHD5,DYNC1LI1,SCOC,NDRG4,SPINT2,MGST3,CALB2,SYT1,ACHE,NDUFA1,RUFY3,SCG5,CEND1,IGFBP5,NDUFB2,TAGLN2,CLU,CNTNAP2,UQCR10,OAZ1,SH3BGRL3,RELN,DNER,DUSP23,PDE4B,COX5B,ETFB,OLFM1,RTN1,GAP43,ISOC1,PCP4,SEZ6L2,TXN,NDUFA5 |
3.234e-03 | -5.73 | cell junction organization | biological process | GO:0034330 | 532 | 6 | 18204 | 50 |
DNER,CD9,SNCA,RELN,SEZ6L2,ACHE |
3.267e-03 | -5.72 | microglial cell activation | biological process | GO:0001774 | 31 | 2 | 18204 | 50 |
CLU,SNCA |
3.267e-03 | -5.72 | negative regulation of amyloid precursor protein catabolic process | biological process | GO:1902992 | 31 | 2 | 18204 | 50 |
CLU,RTN1 |
3.312e-03 | -5.71 | PRUNE1 (prune exopolyphosphatase 1) | protein interactions | 58497 | 34 | 2 | 19454 | 49 |
RUFY3,SNCA |
3.465e-03 | -5.67 | METTL17 (methyltransferase like 17) | protein interactions | 64745 | 406 | 5 | 19454 | 49 |
NDUFB2,ETFB,NDUFA5,COX5B,CLU |
3.511e-03 | -5.65 | UQCRB (ubiquinol-cytochrome c reductase binding protein) | protein interactions | 7381 | 121 | 3 | 19454 | 49 |
NDUFB2,COX6A1,UQCR10 |
3.575e-03 | -5.63 | COX4I1 (cytochrome c oxidase subunit 4I1) | protein interactions | 1327 | 409 | 5 | 19454 | 49 |
MGST3,ETFB,COX6A1,NDUFA5,COX5B |
3.629e-03 | -5.62 | Uptake and actions of bacterial toxins | REACTOME pathways | R-HSA-5339562 | 31 | 2 | 10285 | 30 |
SYT1,CD9 |
3.697e-03 | -5.60 | response to auditory stimulus | biological process | GO:0010996 | 33 | 2 | 18204 | 50 |
GAP43,CNTNAP2 |
3.707e-03 | -5.60 | RAB33A (RAB33A, member RAS oncogene family) | protein interactions | 9363 | 36 | 2 | 19454 | 49 |
SYT1,RUFY3 |
3.761e-03 | -5.58 | PAWR (pro-apoptotic WT1 regulator) | protein interactions | 5074 | 124 | 3 | 19454 | 49 |
SCOC,DYNC1LI1,TXN |
3.761e-03 | -5.58 | COX6C (cytochrome c oxidase subunit 6C) | protein interactions | 1345 | 124 | 3 | 19454 | 49 |
MGST3,COX6A1,NDUFA5 |
3.913e-03 | -5.54 | S100A13 (S100 calcium binding protein A13) | protein interactions | 6284 | 37 | 2 | 19454 | 49 |
MGST3,SYT1 |
3.921e-03 | -5.54 | leukocyte activation involved in inflammatory response | biological process | GO:0002269 | 34 | 2 | 18204 | 50 |
CLU,SNCA |
3.921e-03 | -5.54 | negative regulation of amide metabolic process | biological process | GO:0034249 | 34 | 2 | 18204 | 50 |
RTN1,CLU |
4.123e-03 | -5.49 | CHRM5 (cholinergic receptor muscarinic 5) | protein interactions | 1133 | 38 | 2 | 19454 | 49 |
RTN1,SNCA |
4.123e-03 | -5.49 | HPF1 (histone PARylation factor 1) | protein interactions | 54969 | 38 | 2 | 19454 | 49 |
EMX2,TXN |
4.293e-03 | -5.45 | RSPH1 (radial spoke head component 1) | protein interactions | 89765 | 130 | 3 | 19454 | 49 |
RELN,CLU,DNER |
4.314e-03 | -5.45 | APP (amyloid beta precursor protein) | protein interactions | 351 | 2342 | 13 | 19454 | 49 |
MGST3,SNCA,ACHE,RUFY3,NDUFA5,RELN,OLFM1,ETFB,SPINT2,CLU,COX5B,SH3BGRL3,TAGLN2 |
4.339e-03 | -5.44 | MS4A3 (membrane spanning 4-domains A3) | protein interactions | 932 | 39 | 2 | 19454 | 49 |
IGFBP5,ATP6V0B |
4.339e-03 | -5.44 | ALDH1A2 (aldehyde dehydrogenase 1 family member A2) | protein interactions | 8854 | 39 | 2 | 19454 | 49 |
SH3BGRL3,DYNC1LI1 |
4.362e-03 | -5.43 | chondroblastoma | COSMIC cancer mutations | chondroblastoma | 534 | 6 | 16828 | 49 |
SYT1,CNTNAP2,CD9,THSD7A,PCP4,ETFB |
4.388e-03 | -5.43 | biogenic amine biosynthetic process | biological process | GO:0042401 | 36 | 2 | 18204 | 50 |
OAZ1,SNCA |
4.455e-03 | -5.41 | inorganic cation transmembrane transporter activity | molecular function | GO:0022890 | 589 | 6 | 18094 | 48 |
UQCR10,NDUFA1,NDUFA5,NDUFB2,COX5B,ATP6V0B |
4.561e-03 | -5.39 | NDUFAF8 (NADH:ubiquinone oxidoreductase complex assembly factor 8) | protein interactions | 284184 | 40 | 2 | 19454 | 49 |
COX6A1,NDUFA5 |
4.574e-03 | -5.39 | neuron projection terminus | cellular component | GO:0044306 | 128 | 3 | 19108 | 50 |
CALB2,SYT1,SNCA |
4.631e-03 | -5.38 | amine biosynthetic process | biological process | GO:0009309 | 37 | 2 | 18204 | 50 |
SNCA,OAZ1 |
4.758e-03 | -5.35 | Metabolism | REACTOME pathways | R-HSA-1430728 | 2158 | 13 | 10285 | 30 |
GNG3,UQCR10,COX5B,ACHE,TXN,COX6A1,NDUFA5,OAZ1,RELN,ETFB,NDUFA1,NDUFB2,MGST3 |
4.787e-03 | -5.34 | NDUFA1 (NADH:ubiquinone oxidoreductase subunit A1) | protein interactions | 4694 | 41 | 2 | 19454 | 49 |
NDUFA5,NDUFB2 |
4.806e-03 | -5.34 | positive regulation of protein transport | biological process | GO:0051222 | 249 | 4 | 18204 | 50 |
C1QTNF3,ACHE,RUFY3,OAZ1 |
4.897e-03 | -5.32 | cerebral cortex development | biological process | GO:0021987 | 125 | 3 | 18204 | 50 |
RELN,EMX2,CNTNAP2 |
5.031e-03 | -5.29 | Atp5pb (ATP synthase peripheral stalk-membrane subunit b) | protein interactions | 11950 | 2 | 1 | 19454 | 49 |
SNCA |
5.031e-03 | -5.29 | Epb41l3 (erythrocyte membrane protein band 4.1 like 3) | protein interactions | 13823 | 2 | 1 | 19454 | 49 |
SNCA |
5.031e-03 | -5.29 | NEDD4 (NEDD4 E3 ubiquitin protein ligase) | protein interactions | 103245581 | 2 | 1 | 19454 | 49 |
SNCA |
5.031e-03 | -5.29 | Serpinh1 (serpin family H member 1) | protein interactions | 29345 | 2 | 1 | 19454 | 49 |
SNCA |
5.031e-03 | -5.29 | Atp1a3 (ATPase Na+/K+ transporting subunit alpha 3) | protein interactions | 24213 | 2 | 1 | 19454 | 49 |
SNCA |
5.031e-03 | -5.29 | Ndufs3 (NADH:ubiquinone oxidoreductase core subunit S3) | protein interactions | 68349 | 2 | 1 | 19454 | 49 |
SNCA |
5.031e-03 | -5.29 | Ap2a1 (adaptor-related protein complex 2, alpha 1 subunit) | protein interactions | 11771 | 2 | 1 | 19454 | 49 |
SNCA |
5.031e-03 | -5.29 | Camk2g (calcium/calmodulin-dependent protein kinase II gamma) | protein interactions | 171140 | 2 | 1 | 19454 | 49 |
SNCA |
5.031e-03 | -5.29 | Hspd1 (heat shock protein family D (Hsp60) member 1) | protein interactions | 63868 | 2 | 1 | 19454 | 49 |
SNCA |
5.031e-03 | -5.29 | Cox6c (cytochrome c oxidase subunit 6C) | protein interactions | 12864 | 2 | 1 | 19454 | 49 |
SNCA |
5.031e-03 | -5.29 | YCK3 (casein kinase YCK3) | protein interactions | 856860 | 2 | 1 | 19454 | 49 |
SNCA |
5.031e-03 | -5.29 | MET17 (bifunctional cysteine synthase/O-acetylhomoserine aminocarboxypropyltransferase MET17) | protein interactions | 851010 | 2 | 1 | 19454 | 49 |
SNCA |
5.031e-03 | -5.29 | Atp6v1b2 (ATPase, H+ transporting, lysosomal V1 subunit B2) | protein interactions | 11966 | 2 | 1 | 19454 | 49 |
SNCA |
5.031e-03 | -5.29 | GAPDH (glyceraldehyde-3-phosphate dehydrogenase) | protein interactions | 100009074 | 2 | 1 | 19454 | 49 |
SNCA |
5.031e-03 | -5.29 | Pld2 (phospholipase D2) | protein interactions | 25097 | 2 | 1 | 19454 | 49 |
SNCA |
5.031e-03 | -5.29 | ATG15 (triglyceride lipase ATG15) | protein interactions | 850432 | 2 | 1 | 19454 | 49 |
SNCA |
5.031e-03 | -5.29 | Syt2 (synaptotagmin II) | protein interactions | 20980 | 2 | 1 | 19454 | 49 |
SNCA |
5.031e-03 | -5.29 | MSB3 (Rab GTPase-activating protein MSB3) | protein interactions | 855423 | 2 | 1 | 19454 | 49 |
SNCA |
5.031e-03 | -5.29 | PMA1 (H(+)-exporting P2-type ATPase PMA1) | protein interactions | 852876 | 2 | 1 | 19454 | 49 |
SNCA |
5.031e-03 | -5.29 | Vapa (vesicle-associated membrane protein, associated protein A) | protein interactions | 30960 | 2 | 1 | 19454 | 49 |
SNCA |
5.031e-03 | -5.29 | ube2i.L (ubiquitin conjugating enzyme E2 I L homeolog) | protein interactions | 380450 | 2 | 1 | 19454 | 49 |
SNCA |
5.031e-03 | -5.29 | Hist1h2bg (histone cluster 1, H2bg) | protein interactions | 64647 | 2 | 1 | 19454 | 49 |
SNCA |
5.031e-03 | -5.29 | YGL082W (uncharacterized protein) | protein interactions | 852798 | 2 | 1 | 19454 | 49 |
SNCA |
5.031e-03 | -5.29 | ORA1 (oxidoreductase) | protein interactions | 855266 | 2 | 1 | 19454 | 49 |
SNCA |
5.031e-03 | -5.29 | H2ac21 (H2A clustered histone 21) | protein interactions | 621893 | 2 | 1 | 19454 | 49 |
SNCA |
5.031e-03 | -5.29 | VPS52 (Vps52p) | protein interactions | 852095 | 2 | 1 | 19454 | 49 |
SNCA |
5.031e-03 | -5.29 | NPP1 (nucleotide diphosphatase/phosphodiesterase NPP1) | protein interactions | 850391 | 2 | 1 | 19454 | 49 |
SNCA |
5.031e-03 | -5.29 | STP2 (Stp2p) | protein interactions | 856397 | 2 | 1 | 19454 | 49 |
SNCA |
5.031e-03 | -5.29 | Slc25a1 (solute carrier family 25 (mitochondrial carrier, citrate transporter), member 1) | protein interactions | 13358 | 2 | 1 | 19454 | 49 |
SNCA |
5.031e-03 | -5.29 | Rab3a (RAB3A, member RAS oncogene family) | protein interactions | 19339 | 2 | 1 | 19454 | 49 |
SNCA |
5.031e-03 | -5.29 | Syk (spleen associated tyrosine kinase) | protein interactions | 25155 | 2 | 1 | 19454 | 49 |
SNCA |
5.031e-03 | -5.29 | CALM (calmodulin-like) | protein interactions | 326597 | 2 | 1 | 19454 | 49 |
SNCA |
5.031e-03 | -5.29 | HXT6 (hexose transporter HXT6) | protein interactions | 851944 | 2 | 1 | 19454 | 49 |
SNCA |
5.031e-03 | -5.29 | Atp6v0d1 (ATPase, H+ transporting, lysosomal V0 subunit D1) | protein interactions | 11972 | 2 | 1 | 19454 | 49 |
SNCA |
5.031e-03 | -5.29 | Ina (internexin neuronal intermediate filament protein, alpha) | protein interactions | 226180 | 2 | 1 | 19454 | 49 |
SNCA |
5.031e-03 | -5.29 | TOR1 (phosphatidylinositol kinase-related protein kinase TOR1) | protein interactions | 853529 | 2 | 1 | 19454 | 49 |
SNCA |
5.031e-03 | -5.29 | Tfam (transcription factor A, mitochondrial) | protein interactions | 21780 | 2 | 1 | 19454 | 49 |
SNCA |
5.031e-03 | -5.29 | Tppp (tubulin polymerization promoting protein) | protein interactions | 72948 | 2 | 1 | 19454 | 49 |
SNCA |
5.031e-03 | -5.29 | RSR1 (Ras family GTPase RSR1) | protein interactions | 853056 | 2 | 1 | 19454 | 49 |
SNCA |
5.031e-03 | -5.29 | Gnao1 (G protein subunit alpha o1) | protein interactions | 50664 | 2 | 1 | 19454 | 49 |
SNCA |
5.031e-03 | -5.29 | Rab3a (RAB3A, member RAS oncogene family) | protein interactions | 25531 | 2 | 1 | 19454 | 49 |
SNCA |
5.031e-03 | -5.29 | Chchd3 (coiled-coil-helix-coiled-coil-helix domain containing 3) | protein interactions | 66075 | 2 | 1 | 19454 | 49 |
SNCA |
5.031e-03 | -5.29 | RPT2 (proteasome regulatory particle base subunit RPT2) | protein interactions | 851557 | 2 | 1 | 19454 | 49 |
SNCA |
5.031e-03 | -5.29 | Basp1 (brain abundant, membrane attached signal protein 1) | protein interactions | 64160 | 2 | 1 | 19454 | 49 |
SNCA |
5.031e-03 | -5.29 | SEC4 (Rab family GTPase SEC4) | protein interactions | 850543 | 2 | 1 | 19454 | 49 |
SNCA |
5.031e-03 | -5.29 | Vdac3 (voltage-dependent anion channel 3) | protein interactions | 22335 | 2 | 1 | 19454 | 49 |
SNCA |
5.031e-03 | -5.29 | Syp (synaptophysin) | protein interactions | 20977 | 2 | 1 | 19454 | 49 |
SNCA |
5.031e-03 | -5.29 | Camk2a (calcium/calmodulin-dependent protein kinase II alpha) | protein interactions | 12322 | 2 | 1 | 19454 | 49 |
SNCA |
5.031e-03 | -5.29 | Camk2d (calcium/calmodulin-dependent protein kinase II, delta) | protein interactions | 108058 | 2 | 1 | 19454 | 49 |
SNCA |
5.031e-03 | -5.29 | RAS2 (Ras family GTPase RAS2) | protein interactions | 855625 | 2 | 1 | 19454 | 49 |
SNCA |
5.031e-03 | -5.29 | ITCH (itchy E3 ubiquitin protein ligase) | protein interactions | 103248756 | 2 | 1 | 19454 | 49 |
SNCA |
5.031e-03 | -5.29 | STF1 (ATPase-binding protein) | protein interactions | 851426 | 2 | 1 | 19454 | 49 |
SNCA |
5.031e-03 | -5.29 | Ndufv2 (NADH:ubiquinone oxidoreductase core subunit V2) | protein interactions | 72900 | 2 | 1 | 19454 | 49 |
SNCA |
5.031e-03 | -5.29 | Csnk1a1 (casein kinase 1, alpha 1) | protein interactions | 93687 | 2 | 1 | 19454 | 49 |
SNCA |
5.031e-03 | -5.29 | YCP4 (flavodoxin-like fold family protein) | protein interactions | 850360 | 2 | 1 | 19454 | 49 |
SNCA |
5.031e-03 | -5.29 | Map1a (microtubule-associated protein 1 A) | protein interactions | 17754 | 2 | 1 | 19454 | 49 |
SNCA |
5.031e-03 | -5.29 | Camk2b (calcium/calmodulin-dependent protein kinase II, beta) | protein interactions | 12323 | 2 | 1 | 19454 | 49 |
SNCA |
5.031e-03 | -5.29 | CDC12 (septin CDC12) | protein interactions | 856507 | 2 | 1 | 19454 | 49 |
SNCA |
5.031e-03 | -5.29 | Gnao1 (guanine nucleotide binding protein, alpha O) | protein interactions | 14681 | 2 | 1 | 19454 | 49 |
SNCA |
5.031e-03 | -5.29 | RFS1 (flavodoxin-like fold family protein) | protein interactions | 852341 | 2 | 1 | 19454 | 49 |
SNCA |
5.031e-03 | -5.29 | MAD1 (coiled-coil domain-containing protein MAD1) | protein interactions | 852794 | 2 | 1 | 19454 | 49 |
SNCA |
5.031e-03 | -5.29 | Ndufa13 (NADH:ubiquinone oxidoreductase subunit A13) | protein interactions | 67184 | 2 | 1 | 19454 | 49 |
SNCA |
5.031e-03 | -5.29 | Tuba1b (tubulin, alpha 1B) | protein interactions | 500929 | 2 | 1 | 19454 | 49 |
SNCA |
5.031e-03 | -5.29 | Nefl (neurofilament, light polypeptide) | protein interactions | 18039 | 2 | 1 | 19454 | 49 |
SNCA |
5.031e-03 | -5.29 | Vapb (vesicle-associated membrane protein, associated protein B and C) | protein interactions | 56491 | 2 | 1 | 19454 | 49 |
SNCA |
5.031e-03 | -5.29 | Atp1b1 (ATPase Na+/K+ transporting subunit beta 1) | protein interactions | 25650 | 2 | 1 | 19454 | 49 |
SNCA |
5.031e-03 | -5.29 | Slc25a13 (solute carrier family 25 (mitochondrial carrier, adenine nucleotide translocator), member 13) | protein interactions | 50799 | 2 | 1 | 19454 | 49 |
SNCA |
5.031e-03 | -5.29 | Bcas1 (brain enriched myelin associated protein 1) | protein interactions | 76960 | 2 | 1 | 19454 | 49 |
SNCA |
5.031e-03 | -5.29 | Cox5a (cytochrome c oxidase subunit 5A) | protein interactions | 12858 | 2 | 1 | 19454 | 49 |
SNCA |
5.031e-03 | -5.29 | Srcin1 (SRC kinase signaling inhibitor 1) | protein interactions | 56013 | 2 | 1 | 19454 | 49 |
SNCA |
5.031e-03 | -5.29 | SEY1 (dynamin-like GTPase SEY1) | protein interactions | 854336 | 2 | 1 | 19454 | 49 |
RTN1 |
5.031e-03 | -5.29 | GLO4 (hydroxyacylglutathione hydrolase GLO4) | protein interactions | 854205 | 2 | 1 | 19454 | 49 |
SNCA |
5.031e-03 | -5.29 | SYP1 (Syp1p) | protein interactions | 850396 | 2 | 1 | 19454 | 49 |
SNCA |
5.031e-03 | -5.29 | Sncaip (synuclein, alpha interacting protein) | protein interactions | 307309 | 2 | 1 | 19454 | 49 |
SNCA |
5.031e-03 | -5.29 | NUP53 (FG-nucleoporin NUP53) | protein interactions | 855184 | 2 | 1 | 19454 | 49 |
SNCA |
5.031e-03 | -5.29 | Ndufs2 (NADH:ubiquinone oxidoreductase core subunit S2) | protein interactions | 226646 | 2 | 1 | 19454 | 49 |
SNCA |
5.031e-03 | -5.29 | SOD2 (superoxide dismutase SOD2) | protein interactions | 856399 | 2 | 1 | 19454 | 49 |
SNCA |
5.031e-03 | -5.29 | Ndufv1 (NADH:ubiquinone oxidoreductase core subunit V1) | protein interactions | 17995 | 2 | 1 | 19454 | 49 |
SNCA |
5.031e-03 | -5.29 | CTSW (cathepsin W) | protein interactions | 1521 | 2 | 1 | 19454 | 49 |
EMX2 |
5.031e-03 | -5.29 | Trim3 (tripartite motif-containing 3) | protein interactions | 55992 | 2 | 1 | 19454 | 49 |
SNCA |
5.031e-03 | -5.29 | RTK1 (putative serine/threonine protein kinase RTK1) | protein interactions | 851536 | 2 | 1 | 19454 | 49 |
SNCA |
5.031e-03 | -5.29 | APE2 (metallo-aminopeptidase) | protein interactions | 853699 | 2 | 1 | 19454 | 49 |
SNCA |
5.031e-03 | -5.29 | TSL1 (trehalose 6-phosphate synthase/phosphatase complex subunit) | protein interactions | 854872 | 2 | 1 | 19454 | 49 |
SNCA |
5.031e-03 | -5.29 | Rab5a (RAB5A, member RAS oncogene family) | protein interactions | 271457 | 2 | 1 | 19454 | 49 |
SNCA |
5.070e-03 | -5.28 | NDUFA10 (NADH:ubiquinone oxidoreductase subunit A10) | protein interactions | 4705 | 138 | 3 | 19454 | 49 |
NDUFA1,NDUFA5,COX5B |
5.134e-03 | -5.27 | negative regulation of smooth muscle cell migration | biological process | GO:0014912 | 39 | 2 | 18204 | 50 |
IGFBP5,NDRG4 |
5.134e-03 | -5.27 | glial cell activation | biological process | GO:0061900 | 39 | 2 | 18204 | 50 |
SNCA,CLU |
5.173e-03 | -5.26 | DUSP22 (dual specificity phosphatase 22) | protein interactions | 56940 | 139 | 3 | 19454 | 49 |
TAGLN2,DUSP23,NRN1 |
5.227e-03 | -5.25 | electron transfer flavoprotein complex | cellular component | GO:0045251 | 2 | 1 | 19108 | 50 |
ETFB |
5.246e-03 | -5.25 | Cytochrome c oxidase, subunit VIa | gene3d domains | 4.10.95.10 | 2 | 1 | 14470 | 38 |
COX6A1 |
5.246e-03 | -5.25 | lithium bound rotor ring of v- atpase | gene3d domains | 1.20.120.610 | 2 | 1 | 14470 | 38 |
ATP6V0B |
5.246e-03 | -5.25 | Isochorismatase-like | gene3d domains | 3.40.50.850 | 2 | 1 | 14470 | 38 |
ISOC1 |
5.284e-03 | -5.24 | AChE_tetra | interpro domains | IPR014788 | 2 | 1 | 18521 | 49 |
ACHE |
5.284e-03 | -5.24 | Isochorismatase-like_sf | interpro domains | IPR036380 | 2 | 1 | 18521 | 49 |
ISOC1 |
5.284e-03 | -5.24 | Isochorismatase-like | interpro domains | IPR000868 | 2 | 1 | 18521 | 49 |
ISOC1 |
5.284e-03 | -5.24 | Gastrin/CCK | interpro domains | IPR001651 | 2 | 1 | 18521 | 49 |
CCK |
5.284e-03 | -5.24 | ETF_a/b_N | interpro domains | IPR014730 | 2 | 1 | 18521 | 49 |
ETFB |
5.284e-03 | -5.24 | Clusterin_C | interpro domains | IPR016015 | 2 | 1 | 18521 | 49 |
CLU |
5.284e-03 | -5.24 | ATPase_proteolipid_csu | interpro domains | IPR000245 | 2 | 1 | 18521 | 49 |
ATP6V0B |
5.284e-03 | -5.24 | Neuritin_fam | interpro domains | IPR026144 | 2 | 1 | 18521 | 49 |
NRN1 |
5.284e-03 | -5.24 | Cyt_c_oxidase_su6a_CS | interpro domains | IPR018507 | 2 | 1 | 18521 | 49 |
COX6A1 |
5.284e-03 | -5.24 | Dynein1_light_intermed_chain | interpro domains | IPR008467 | 2 | 1 | 18521 | 49 |
DYNC1LI1 |
5.284e-03 | -5.24 | Cholinesterase | interpro domains | IPR000997 | 2 | 1 | 18521 | 49 |
ACHE |
5.284e-03 | -5.24 | Cyt_c_oxidase_su6a | interpro domains | IPR001349 | 2 | 1 | 18521 | 49 |
COX6A1 |
5.284e-03 | -5.24 | Thioredoxin | interpro domains | IPR005746 | 2 | 1 | 18521 | 49 |
TXN |
5.284e-03 | -5.24 | Clusterin_N | interpro domains | IPR016014 | 2 | 1 | 18521 | 49 |
CLU |
5.284e-03 | -5.24 | Cyt_c_oxidase_su6a_sf | interpro domains | IPR036418 | 2 | 1 | 18521 | 49 |
COX6A1 |
5.284e-03 | -5.24 | Gastrin/cholecystokinin_CS | interpro domains | IPR013152 | 2 | 1 | 18521 | 49 |
CCK |
5.284e-03 | -5.24 | Clusterin-like | interpro domains | IPR000753 | 2 | 1 | 18521 | 49 |
CLU |
5.299e-03 | -5.24 | calcium ion binding involved in regulation of cytosolic calcium ion concentration | molecular function | GO:0099510 | 2 | 1 | 18094 | 48 |
CALB2 |
5.299e-03 | -5.24 | calcium ion binding involved in regulation of presynaptic cytosolic calcium ion concentration | molecular function | GO:0099534 | 2 | 1 | 18094 | 48 |
CALB2 |
5.299e-03 | -5.24 | syntaxin-3 binding | molecular function | GO:0030348 | 2 | 1 | 18094 | 48 |
SYT1 |
5.299e-03 | -5.24 | acetylcholinesterase activity | molecular function | GO:0003990 | 2 | 1 | 18094 | 48 |
ACHE |
5.345e-03 | -5.23 | ETF | smart domains | SM00893 | 2 | 1 | 9717 | 26 |
ETFB |
5.345e-03 | -5.23 | GASTRIN | smart domains | SM00029 | 2 | 1 | 9717 | 26 |
CCK |
5.345e-03 | -5.23 | CLb | smart domains | SM00030 | 2 | 1 | 9717 | 26 |
CLU |
5.345e-03 | -5.23 | CLa | smart domains | SM00035 | 2 | 1 | 9717 | 26 |
CLU |
5.409e-03 | -5.22 | COX6A | prosite domains | PS01329 | 2 | 1 | 12186 | 33 |
COX6A1 |
5.409e-03 | -5.22 | GASTRIN | prosite domains | PS00259 | 2 | 1 | 12186 | 33 |
CCK |
5.486e-03 | -5.21 | positive regulation of peroxidase activity | biological process | GO:2000470 | 2 | 1 | 18204 | 50 |
SNCA |
5.486e-03 | -5.21 | regulation of peroxidase activity | biological process | GO:2000468 | 2 | 1 | 18204 | 50 |
SNCA |
5.486e-03 | -5.21 | regulation of neurofibrillary tangle assembly | biological process | GO:1902996 | 2 | 1 | 18204 | 50 |
CLU |
5.486e-03 | -5.21 | regulation of skeletal muscle hypertrophy | biological process | GO:1904204 | 2 | 1 | 18204 | 50 |
IGFBP5 |
5.486e-03 | -5.21 | acetylcholine catabolic process in synaptic cleft | biological process | GO:0001507 | 2 | 1 | 18204 | 50 |
ACHE |
5.486e-03 | -5.21 | positive regulation of hydrogen peroxide catabolic process | biological process | GO:1903285 | 2 | 1 | 18204 | 50 |
SNCA |
5.486e-03 | -5.21 | regulation of norepinephrine uptake | biological process | GO:0051621 | 2 | 1 | 18204 | 50 |
SNCA |
5.486e-03 | -5.21 | regulation of mesenchymal cell proliferation involved in lung development | biological process | GO:2000790 | 2 | 1 | 18204 | 50 |
NFIB |
5.486e-03 | -5.21 | superior temporal gyrus development | biological process | GO:0071109 | 2 | 1 | 18204 | 50 |
CNTNAP2 |
5.486e-03 | -5.21 | cellular detoxification of hydrogen peroxide | biological process | GO:0061692 | 2 | 1 | 18204 | 50 |
TXN |
5.486e-03 | -5.21 | cell differentiation involved in salivary gland development | biological process | GO:0060689 | 2 | 1 | 18204 | 50 |
NFIB |
5.486e-03 | -5.21 | negative regulation of mesenchymal cell proliferation involved in lung development | biological process | GO:2000791 | 2 | 1 | 18204 | 50 |
NFIB |
5.486e-03 | -5.21 | negative regulation of cerebellar granule cell precursor proliferation | biological process | GO:0021941 | 2 | 1 | 18204 | 50 |
CEND1 |
5.486e-03 | -5.21 | negative regulation of relaxation of cardiac muscle | biological process | GO:1901898 | 2 | 1 | 18204 | 50 |
PDE4B |
5.489e-03 | -5.21 | GOLM1 (golgi membrane protein 1) | protein interactions | 51280 | 142 | 3 | 19454 | 49 |
IGFBP5,SYT1,THSD7A |
5.500e-03 | -5.20 | Isochorismatase | pfam domains | PF00857 | 2 | 1 | 17795 | 49 |
ISOC1 |
5.500e-03 | -5.20 | NRN1 | pfam domains | PF15056 | 2 | 1 | 17795 | 49 |
NRN1 |
5.500e-03 | -5.20 | Clusterin | pfam domains | PF01093 | 2 | 1 | 17795 | 49 |
CLU |
5.500e-03 | -5.20 | COX6A | pfam domains | PF02046 | 2 | 1 | 17795 | 49 |
COX6A1 |
5.500e-03 | -5.20 | ETF | pfam domains | PF01012 | 2 | 1 | 17795 | 49 |
ETFB |
5.500e-03 | -5.20 | AChE_tetra | pfam domains | PF08674 | 2 | 1 | 17795 | 49 |
ACHE |
5.500e-03 | -5.20 | Gastrin | pfam domains | PF00918 | 2 | 1 | 17795 | 49 |
CCK |
5.580e-03 | -5.19 | negative regulation of cell population proliferation | biological process | GO:0008285 | 791 | 7 | 18204 | 50 |
SPINT2,IGFBP5,CEND1,NFIB,CD9,CHD5,NDRG4 |
5.638e-03 | -5.18 | clathrin-coated vesicle membrane | cellular component | GO:0030665 | 138 | 3 | 19108 | 50 |
ATP6V0B,CD9,SYT1 |
5.706e-03 | -5.17 | COX14 (cytochrome c oxidase assembly factor COX14) | protein interactions | 84987 | 144 | 3 | 19454 | 49 |
COX5B,NDUFA5,ETFB |
5.732e-03 | -5.16 | VACATPASE | prints domains | PR00122 | 2 | 1 | 5227 | 15 |
ATP6V0B |
5.732e-03 | -5.16 | CHOLNESTRASE | prints domains | PR00878 | 2 | 1 | 5227 | 15 |
ACHE |
5.806e-03 | -5.15 | tau protein binding | molecular function | GO:0048156 | 43 | 2 | 18094 | 48 |
SNCA,CLU |
5.902e-03 | -5.13 | regulation of intracellular transport | biological process | GO:0032386 | 264 | 4 | 18204 | 50 |
NDRG4,OAZ1,TXN,RUFY3 |
5.935e-03 | -5.13 | regulation of catecholamine secretion | biological process | GO:0050433 | 42 | 2 | 18204 | 50 |
SNCA,SYT1 |
6.155e-03 | -5.09 | LRP2 (LDL receptor related protein 2) | protein interactions | 4036 | 148 | 3 | 19454 | 49 |
SYT1,CLU,EMX2 |
6.159e-03 | -5.09 | monoatomic cation transmembrane transporter activity | molecular function | GO:0008324 | 630 | 6 | 18094 | 48 |
ATP6V0B,COX5B,NDUFB2,NDUFA5,NDUFA1,UQCR10 |
6.187e-03 | -5.09 | proton transmembrane transport | biological process | GO:1902600 | 136 | 3 | 18204 | 50 |
UQCR10,ATP6V0B,COX5B |
6.314e-03 | -5.07 | cell recognition | biological process | GO:0008037 | 137 | 3 | 18204 | 50 |
CNTNAP2,CD9,GAP43 |
6.321e-03 | -5.06 | Burkitt_lymphoma | COSMIC cancer mutations | Burkitt_lymphoma | 2119 | 13 | 16828 | 49 |
RTN1,NFIB,OLFM1,PCP4,SCG5,PDE4B,RELN,SYT1,CNTNAP2,DNER,THSD7A,SNCA,GAP43 |
6.321e-03 | -5.06 | haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-Burkitt_lymphoma | COSMIC cancer mutations | haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-Burkitt_lymphoma | 2119 | 13 | 16828 | 49 |
SNCA,GAP43,THSD7A,DNER,SYT1,CNTNAP2,RELN,SCG5,PDE4B,PCP4,OLFM1,RTN1,NFIB |
6.346e-03 | -5.06 | multicellular organismal process | biological process | GO:0032501 | 6177 | 26 | 18204 | 50 |
MAB21L1,ACHE,EMX2,GAP43,NFIB,NHLH2,CNTNAP2,OLFM1,PDE4B,COX5B,DNER,NDRG4,SPINT2,RELN,RUFY3,CCK,THSD7A,SEZ6L2,SNCA,RTN1,IGFBP5,NRN1,CD9,CEND1,CHD5,CLU |
6.424e-03 | -5.05 | MTIF3 (mitochondrial translational initiation factor 3) | protein interactions | 219402 | 295 | 4 | 19454 | 49 |
NDRG4,NDUFA5,ETFB,MGST3 |
6.498e-03 | -5.04 | regulation of release of cytochrome c from mitochondria | biological process | GO:0090199 | 44 | 2 | 18204 | 50 |
CLU,MLLT11 |
6.505e-03 | -5.04 | UQCRQ (ubiquinol-cytochrome c reductase complex III subunit VII) | protein interactions | 27089 | 151 | 3 | 19454 | 49 |
UQCR10,COX6A1,MGST3 |
6.513e-03 | -5.03 | Platelet degranulation | REACTOME pathways | R-HSA-114608 | 132 | 3 | 10285 | 30 |
CD9,TAGLN2,CLU |
6.544e-03 | -5.03 | regulation of protein transport | biological process | GO:0051223 | 433 | 5 | 18204 | 50 |
C1QTNF3,OAZ1,TXN,RUFY3,ACHE |
6.607e-03 | -5.02 | mitochondrion organization | biological process | GO:0007005 | 434 | 5 | 18204 | 50 |
NDUFA1,NDUFA5,SNCA,CLU,NDUFB2 |
6.777e-03 | -4.99 | COX6A1 (cytochrome c oxidase subunit 6A1) | protein interactions | 1337 | 49 | 2 | 19454 | 49 |
COX5B,NDUFA5 |
6.777e-03 | -4.99 | MEIS1 (Meis homeobox 1) | protein interactions | 4211 | 49 | 2 | 19454 | 49 |
MAB21L1,EMX2 |
6.813e-03 | -4.99 | organelle organization | biological process | GO:0006996 | 3091 | 16 | 18204 | 50 |
NDUFA5,NDUFB2,THSD7A,ATP6V0B,RTN1,NFIB,SNCA,NDUFA1,RUFY3,DUSP23,DYNC1LI1,CLU,CHD5,SH3BGRL3,TAGLN2,RELN |
6.889e-03 | -4.98 | TOMM40 (translocase of outer mitochondrial membrane 40) | protein interactions | 10452 | 301 | 4 | 19454 | 49 |
TAGLN2,RTN1,COX5B,MGST3 |
6.890e-03 | -4.98 | telencephalon development | biological process | GO:0021537 | 276 | 4 | 18204 | 50 |
EMX2,RELN,NFIB,CNTNAP2 |
7.049e-03 | -4.95 | PITPNB (phosphatidylinositol transfer protein beta) | protein interactions | 23760 | 50 | 2 | 19454 | 49 |
ETFB,TAGLN2 |
7.084e-03 | -4.95 | glial cell migration | biological process | GO:0008347 | 46 | 2 | 18204 | 50 |
CD9,RELN |
7.084e-03 | -4.95 | neuron recognition | biological process | GO:0008038 | 46 | 2 | 18204 | 50 |
CNTNAP2,GAP43 |
7.115e-03 | -4.95 | LCN2 (lipocalin 2) | protein interactions | 3934 | 156 | 3 | 19454 | 49 |
PCP4,OAZ1,NDUFB2 |
7.115e-03 | -4.95 | SASS6 (SAS-6 centriolar assembly protein) | protein interactions | 163786 | 156 | 3 | 19454 | 49 |
SCOC,NFIB,ISOC1 |
7.217e-03 | -4.93 | Response to elevated platelet cytosolic Ca2+ | REACTOME pathways | R-HSA-76005 | 137 | 3 | 10285 | 30 |
CD9,TAGLN2,CLU |
7.325e-03 | -4.92 | DOCK6 (dedicator of cytokinesis 6) | protein interactions | 57572 | 51 | 2 | 19454 | 49 |
CLU,DYNC1LI1 |
7.325e-03 | -4.92 | PCDHGC3 (protocadherin gamma subfamily C, 3) | protein interactions | 5098 | 51 | 2 | 19454 | 49 |
NRN1,GAP43 |
7.325e-03 | -4.92 | NDUFB6 (NADH:ubiquinone oxidoreductase subunit B6) | protein interactions | 4712 | 51 | 2 | 19454 | 49 |
NDUFA1,SNCA |
7.325e-03 | -4.92 | CPE (carboxypeptidase E) | protein interactions | 1363 | 51 | 2 | 19454 | 49 |
CCK,CNTNAP2 |
7.386e-03 | -4.91 | regulation of long-term synaptic potentiation | biological process | GO:1900271 | 47 | 2 | 18204 | 50 |
RELN,CALB2 |
7.496e-03 | -4.89 | APOA1 (apolipoprotein A1) | protein interactions | 335 | 159 | 3 | 19454 | 49 |
SNCA,PDE4B,CLU |
7.521e-03 | -4.89 | regulation of intracellular protein transport | biological process | GO:0033157 | 146 | 3 | 18204 | 50 |
RUFY3,OAZ1,TXN |
7.521e-03 | -4.89 | adult behavior | biological process | GO:0030534 | 146 | 3 | 18204 | 50 |
CNTNAP2,SNCA,CEND1 |
7.538e-03 | -4.89 | HMX2 (H6 family homeobox 2) | protein interactions | 3167 | 3 | 1 | 19454 | 49 |
CALB2 |
7.538e-03 | -4.89 | Atp5f1c (ATP synthase F1 subunit gamma) | protein interactions | 11949 | 3 | 1 | 19454 | 49 |
SNCA |
7.538e-03 | -4.89 | YGR130C (uncharacterized protein) | protein interactions | 853031 | 3 | 1 | 19454 | 49 |
SNCA |
7.538e-03 | -4.89 | Tuba4a (tubulin, alpha 4A) | protein interactions | 22145 | 3 | 1 | 19454 | 49 |
SNCA |
7.538e-03 | -4.89 | HSP30 (Hsp30p) | protein interactions | 850385 | 3 | 1 | 19454 | 49 |
SNCA |
7.538e-03 | -4.89 | Phb1 (prohibitin 1) | protein interactions | 18673 | 3 | 1 | 19454 | 49 |
SNCA |
7.538e-03 | -4.89 | Csnk2b (casein kinase 2 beta) | protein interactions | 81650 | 3 | 1 | 19454 | 49 |
SNCA |
7.538e-03 | -4.89 | Sumo1 (small ubiquitin-like modifier 1) | protein interactions | 22218 | 3 | 1 | 19454 | 49 |
SNCA |
7.538e-03 | -4.89 | Lep (leptin) | protein interactions | 16846 | 3 | 1 | 19454 | 49 |
CLU |
7.538e-03 | -4.89 | Hsp90aa1 (heat shock protein 90 alpha family class A member 1) | protein interactions | 299331 | 3 | 1 | 19454 | 49 |
SNCA |
7.538e-03 | -4.89 | Prkn (parkin RBR E3 ubiquitin protein ligase) | protein interactions | 50873 | 3 | 1 | 19454 | 49 |
SNCA |
7.538e-03 | -4.89 | Map4 (microtubule-associated protein 4) | protein interactions | 17758 | 3 | 1 | 19454 | 49 |
SNCA |
7.538e-03 | -4.89 | THR1 (homoserine kinase) | protein interactions | 856420 | 3 | 1 | 19454 | 49 |
SNCA |
7.538e-03 | -4.89 | COX2 (cytochrome c oxidase subunit II) | protein interactions | 17709 | 3 | 1 | 19454 | 49 |
SNCA |
7.538e-03 | -4.89 | Hsp90ab1 (heat shock protein 90 alpha family class B member 1) | protein interactions | 301252 | 3 | 1 | 19454 | 49 |
SNCA |
7.538e-03 | -4.89 | OPI3 (bifunctional phosphatidyl-N-methylethanolamine N-methyltransferase/phosphatidyl-N-dimethylethanolamine N-methyltransferase) | protein interactions | 853536 | 3 | 1 | 19454 | 49 |
SNCA |
7.538e-03 | -4.89 | YCR051W (uncharacterized protein) | protein interactions | 850418 | 3 | 1 | 19454 | 49 |
SNCA |
7.538e-03 | -4.89 | Cnp (2',3'-cyclic nucleotide 3' phosphodiesterase) | protein interactions | 12799 | 3 | 1 | 19454 | 49 |
SNCA |
7.538e-03 | -4.89 | Slc1a2 (solute carrier family 1 (glial high affinity glutamate transporter), member 2) | protein interactions | 20511 | 3 | 1 | 19454 | 49 |
SNCA |
7.538e-03 | -4.89 | Myo5a (myosin VA) | protein interactions | 17918 | 3 | 1 | 19454 | 49 |
SNCA |
7.538e-03 | -4.89 | Phb2 (prohibitin 2) | protein interactions | 12034 | 3 | 1 | 19454 | 49 |
SNCA |
7.538e-03 | -4.89 | Vdac1 (voltage-dependent anion channel 1) | protein interactions | 22333 | 3 | 1 | 19454 | 49 |
SNCA |
7.538e-03 | -4.89 | Vdac1 (voltage-dependent anion channel 1) | protein interactions | 83529 | 3 | 1 | 19454 | 49 |
SNCA |
7.538e-03 | -4.89 | Cfl1 (cofilin 1) | protein interactions | 29271 | 3 | 1 | 19454 | 49 |
SNCA |
7.538e-03 | -4.89 | Ndufa9 (NADH:ubiquinone oxidoreductase subunit A9) | protein interactions | 66108 | 3 | 1 | 19454 | 49 |
SNCA |
7.538e-03 | -4.89 | Slc25a22 (solute carrier family 25 (mitochondrial carrier, glutamate), member 22) | protein interactions | 68267 | 3 | 1 | 19454 | 49 |
SNCA |
7.538e-03 | -4.89 | YHB1 (flavohemoglobin) | protein interactions | 853149 | 3 | 1 | 19454 | 49 |
SNCA |
7.538e-03 | -4.89 | PRIMA1 (proline rich membrane anchor 1) | protein interactions | 145270 | 3 | 1 | 19454 | 49 |
ACHE |
7.538e-03 | -4.89 | Hk1 (hexokinase 1) | protein interactions | 15275 | 3 | 1 | 19454 | 49 |
SNCA |
7.538e-03 | -4.89 | Lyn (LYN proto-oncogene, Src family tyrosine kinase) | protein interactions | 81515 | 3 | 1 | 19454 | 49 |
SNCA |
7.538e-03 | -4.89 | Glul (glutamate-ammonia ligase) | protein interactions | 14645 | 3 | 1 | 19454 | 49 |
SNCA |
7.538e-03 | -4.89 | Snca (synuclein, alpha) | protein interactions | 20617 | 3 | 1 | 19454 | 49 |
SNCA |
7.538e-03 | -4.89 | SEC14 (phosphatidylinositol/phosphatidylcholine transfer protein SEC14) | protein interactions | 855103 | 3 | 1 | 19454 | 49 |
SNCA |
7.538e-03 | -4.89 | Epb41l2 (erythrocyte membrane protein band 4.1 like 2) | protein interactions | 13822 | 3 | 1 | 19454 | 49 |
SNCA |
7.538e-03 | -4.89 | CCKAR (cholecystokinin A receptor) | protein interactions | 886 | 3 | 1 | 19454 | 49 |
CCK |
7.538e-03 | -4.89 | Brsk1 (BR serine/threonine kinase 1) | protein interactions | 381979 | 3 | 1 | 19454 | 49 |
SNCA |
7.626e-03 | -4.88 | APOD (apolipoprotein D) | protein interactions | 347 | 160 | 3 | 19454 | 49 |
PCP4,ATP6V0B,MGST3 |
7.694e-03 | -4.87 | regulation of amyloid-beta formation | biological process | GO:1902003 | 48 | 2 | 18204 | 50 |
RTN1,CLU |
7.702e-03 | -4.87 | animal organ development | biological process | GO:0048513 | 2846 | 15 | 18204 | 50 |
RTN1,NHLH2,NFIB,IGFBP5,EMX2,MAB21L1,ACHE,DNER,CEND1,OLFM1,CNTNAP2,RELN,SPINT2,CHD5,NDRG4 |
7.758e-03 | -4.86 | AK2 (adenylate kinase 2) | protein interactions | 204 | 161 | 3 | 19454 | 49 |
TXN,SH3BGRL3,ETFB |
7.830e-03 | -4.85 | clathrin-sculpted acetylcholine transport vesicle membrane | cellular component | GO:0060201 | 3 | 1 | 19108 | 50 |
SYT1 |
7.830e-03 | -4.85 | clathrin-sculpted acetylcholine transport vesicle | cellular component | GO:0060200 | 3 | 1 | 19108 | 50 |
SYT1 |
7.858e-03 | -4.85 | Helix hairpin bin | gene3d domains | 1.10.287.700 | 3 | 1 | 14470 | 38 |
SNCA |
7.858e-03 | -4.85 | Reeler domain | gene3d domains | 2.60.40.4060 | 3 | 1 | 14470 | 38 |
RELN |
7.858e-03 | -4.85 | - | gene3d domains | 3.40.630.60 | 3 | 1 | 14470 | 38 |
OAZ1 |
7.895e-03 | -4.84 | Folic Acid Network | WikiPathways | WP1273 | 2 | 1 | 5310 | 21 |
TXN |
7.895e-03 | -4.84 | Folic Acid Network | WikiPathways | WP1311 | 2 | 1 | 5310 | 21 |
TXN |
7.916e-03 | -4.84 | CHD_II_SANT-like | interpro domains | IPR009462 | 3 | 1 | 18521 | 49 |
CHD5 |
7.916e-03 | -4.84 | Reeler_dom | interpro domains | IPR002861 | 3 | 1 | 18521 | 49 |
RELN |
7.916e-03 | -4.84 | Noelin_dom | interpro domains | IPR022082 | 3 | 1 | 18521 | 49 |
OLFM1 |
7.916e-03 | -4.84 | ODC_AZ | interpro domains | IPR002993 | 3 | 1 | 18521 | 49 |
OAZ1 |
7.916e-03 | -4.84 | Reeler_sf | interpro domains | IPR042307 | 3 | 1 | 18521 | 49 |
RELN |
7.916e-03 | -4.84 | CHD_C2 | interpro domains | IPR012957 | 3 | 1 | 18521 | 49 |
CHD5 |
7.916e-03 | -4.84 | ODC_AZ_sf | interpro domains | IPR038581 | 3 | 1 | 18521 | 49 |
OAZ1 |
7.916e-03 | -4.84 | CHD_N | interpro domains | IPR012958 | 3 | 1 | 18521 | 49 |
CHD5 |
7.916e-03 | -4.84 | DUF1087 | interpro domains | IPR009463 | 3 | 1 | 18521 | 49 |
CHD5 |
7.916e-03 | -4.84 | RUFY1-3 | interpro domains | IPR047335 | 3 | 1 | 18521 | 49 |
RUFY3 |
7.916e-03 | -4.84 | Dynein_light_int_chain | interpro domains | IPR022780 | 3 | 1 | 18521 | 49 |
DYNC1LI1 |
7.916e-03 | -4.84 | Synuclein | interpro domains | IPR001058 | 3 | 1 | 18521 | 49 |
SNCA |
7.938e-03 | -4.84 | cholinesterase activity | molecular function | GO:0004104 | 3 | 1 | 18094 | 48 |
ACHE |
7.938e-03 | -4.84 | ornithine decarboxylase inhibitor activity | molecular function | GO:0008073 | 3 | 1 | 18094 | 48 |
OAZ1 |
8.007e-03 | -4.83 | DUF1087 | smart domains | SM01147 | 3 | 1 | 9717 | 26 |
CHD5 |
8.007e-03 | -4.83 | DUF1086 | smart domains | SM01146 | 3 | 1 | 9717 | 26 |
CHD5 |
8.079e-03 | -4.82 | positive regulation of secretion by cell | biological process | GO:1903532 | 289 | 4 | 18204 | 50 |
C1QTNF3,SNCA,SYT1,ACHE |
8.103e-03 | -4.82 | ODC_AZ | prosite domains | PS01337 | 3 | 1 | 12186 | 33 |
OAZ1 |
8.103e-03 | -4.82 | REELIN | prosite domains | PS51019 | 3 | 1 | 12186 | 33 |
RELN |
8.181e-03 | -4.81 | PLCD1 (phospholipase C delta 1) | protein interactions | 5333 | 54 | 2 | 19454 | 49 |
GAP43,SCG5 |
8.218e-03 | -4.80 | immune complex clearance | biological process | GO:0002434 | 3 | 1 | 18204 | 50 |
CLU |
8.218e-03 | -4.80 | epithelial cell differentiation involved in embryonic placenta development | biological process | GO:0060671 | 3 | 1 | 18204 | 50 |
SPINT2 |
8.218e-03 | -4.80 | acetylcholine catabolic process | biological process | GO:0006581 | 3 | 1 | 18204 | 50 |
ACHE |
8.218e-03 | -4.80 | detoxification of hydrogen peroxide | biological process | GO:0061691 | 3 | 1 | 18204 | 50 |
TXN |
8.218e-03 | -4.80 | negative regulation of serotonin uptake | biological process | GO:0051612 | 3 | 1 | 18204 | 50 |
SNCA |
8.218e-03 | -4.80 | negative regulation of polyamine transmembrane transport | biological process | GO:1902268 | 3 | 1 | 18204 | 50 |
OAZ1 |
8.218e-03 | -4.80 | positive regulation of adiponectin secretion | biological process | GO:0070165 | 3 | 1 | 18204 | 50 |
C1QTNF3 |
8.218e-03 | -4.80 | positive regulation of peptidyl-cysteine S-nitrosylation | biological process | GO:2000170 | 3 | 1 | 18204 | 50 |
TXN |
8.218e-03 | -4.80 | regulation of thrombin-activated receptor signaling pathway | biological process | GO:0070494 | 3 | 1 | 18204 | 50 |
SNCA |
8.218e-03 | -4.80 | lateral motor column neuron migration | biological process | GO:0097477 | 3 | 1 | 18204 | 50 |
RELN |
8.218e-03 | -4.80 | negative regulation of neurotransmitter uptake | biological process | GO:0051581 | 3 | 1 | 18204 | 50 |
SNCA |
8.218e-03 | -4.80 | negative regulation of mitochondrial electron transport, NADH to ubiquinone | biological process | GO:1902957 | 3 | 1 | 18204 | 50 |
SNCA |
8.218e-03 | -4.80 | epithelial cell morphogenesis involved in placental branching | biological process | GO:0060672 | 3 | 1 | 18204 | 50 |
SPINT2 |
8.218e-03 | -4.80 | negative regulation of mitochondrial ATP synthesis coupled electron transport | biological process | GO:1905447 | 3 | 1 | 18204 | 50 |
SNCA |
8.218e-03 | -4.80 | protein targeting to lysosome involved in chaperone-mediated autophagy | biological process | GO:0061740 | 3 | 1 | 18204 | 50 |
CLU |
8.218e-03 | -4.80 | sulfide oxidation | biological process | GO:0019418 | 3 | 1 | 18204 | 50 |
TSTD1 |
8.218e-03 | -4.80 | cerebellum maturation | biological process | GO:0021590 | 3 | 1 | 18204 | 50 |
CEND1 |
8.218e-03 | -4.80 | regulation of synaptic activity | biological process | GO:0060025 | 3 | 1 | 18204 | 50 |
RELN |
8.218e-03 | -4.80 | negative regulation of thrombin-activated receptor signaling pathway | biological process | GO:0070495 | 3 | 1 | 18204 | 50 |
SNCA |
8.218e-03 | -4.80 | positive regulation of synaptic vesicle exocytosis | biological process | GO:2000302 | 3 | 1 | 18204 | 50 |
SYT1 |
8.218e-03 | -4.80 | sulfide oxidation, using sulfide:quinone oxidoreductase | biological process | GO:0070221 | 3 | 1 | 18204 | 50 |
TSTD1 |
8.218e-03 | -4.80 | negative regulation of chaperone-mediated autophagy | biological process | GO:1904715 | 3 | 1 | 18204 | 50 |
SNCA |
8.218e-03 | -4.80 | cerebellar cortex maturation | biological process | GO:0021699 | 3 | 1 | 18204 | 50 |
CEND1 |
8.238e-03 | -4.80 | Synuclein | pfam domains | PF01387 | 3 | 1 | 17795 | 49 |
SNCA |
8.238e-03 | -4.80 | DLIC | pfam domains | PF05783 | 3 | 1 | 17795 | 49 |
DYNC1LI1 |
8.238e-03 | -4.80 | Noelin-1 | pfam domains | PF12308 | 3 | 1 | 17795 | 49 |
OLFM1 |
8.238e-03 | -4.80 | CHDII_SANT-like | pfam domains | PF06461 | 3 | 1 | 17795 | 49 |
CHD5 |
8.238e-03 | -4.80 | CHDNT | pfam domains | PF08073 | 3 | 1 | 17795 | 49 |
CHD5 |
8.238e-03 | -4.80 | DUF1087 | pfam domains | PF06465 | 3 | 1 | 17795 | 49 |
CHD5 |
8.238e-03 | -4.80 | ODC_AZ | pfam domains | PF02100 | 3 | 1 | 17795 | 49 |
OAZ1 |
8.238e-03 | -4.80 | CHDCT2 | pfam domains | PF08074 | 3 | 1 | 17795 | 49 |
CHD5 |
8.296e-03 | -4.79 | SCO1 (synthesis of cytochrome C oxidase 1) | protein interactions | 6341 | 165 | 3 | 19454 | 49 |
COX5B,NDUFA5,ETFB |
8.327e-03 | -4.79 | neuroinflammatory response | biological process | GO:0150076 | 50 | 2 | 18204 | 50 |
CLU,SNCA |
8.329e-03 | -4.79 | PPIA (peptidylprolyl isomerase A) | protein interactions | 5478 | 318 | 4 | 19454 | 49 |
TAGLN2,SNCA,PDE4B,ETFB |
8.397e-03 | -4.78 | ATP metabolic process | biological process | GO:0046034 | 152 | 3 | 18204 | 50 |
NDUFB2,NDUFA5,NDUFA1 |
8.434e-03 | -4.78 | HINT1 (histidine triad nucleotide binding protein 1) | protein interactions | 3094 | 166 | 3 | 19454 | 49 |
TXN,SNCA,TAGLN2 |
8.436e-03 | -4.78 | protein binding | molecular function | GO:0005515 | 13983 | 44 | 18094 | 48 |
RELN,SCG5,UQCR10,ATP6V0B,ISOC1,NDUFA5,ETFB,CEND1,C1QTNF3,THSD7A,DNER,IGFBP5,TAGLN2,CHD5,DUSP23,NDRG4,MLLT11,ACHE,SYT1,SNCA,DYNC1LI1,SCOC,OLFM1,NFIB,GAP43,COX6A1,CCK,CLU,MGST3,SH3BGRL3,TXN,TSTD1,RTN1,MAB21L1,CNTNAP2,GNG3,COX5B,NHLH2,CD9,OAZ1,RUFY3,EMX2,PCP4,PDE4B |
8.477e-03 | -4.77 | GJB7 (gap junction protein beta 7) | protein interactions | 375519 | 55 | 2 | 19454 | 49 |
NRN1,GAP43 |
8.586e-03 | -4.76 | TRANSGELIN | prints domains | PR00890 | 3 | 1 | 5227 | 15 |
TAGLN2 |
8.586e-03 | -4.76 | SYNUCLEIN | prints domains | PR01211 | 3 | 1 | 5227 | 15 |
SNCA |
8.645e-03 | -4.75 | neuron development | biological process | GO:0048666 | 859 | 7 | 18204 | 50 |
NFIB,NHLH2,RELN,GAP43,CCK,CNTNAP2,NRN1 |
8.645e-03 | -4.75 | Platelet activation, signaling and aggregation | REACTOME pathways | R-HSA-76002 | 282 | 4 | 10285 | 30 |
CLU,TAGLN2,CD9,GNG3 |
8.694e-03 | -4.75 | DNM1L (dynamin 1 like) | protein interactions | 10059 | 322 | 4 | 19454 | 49 |
DUSP23,TAGLN2,MGST3,TXN |
8.702e-03 | -4.74 | hindbrain development | biological process | GO:0030902 | 154 | 3 | 18204 | 50 |
CEND1,NFIB,NHLH2 |
8.702e-03 | -4.74 | learning | biological process | GO:0007612 | 154 | 3 | 18204 | 50 |
RELN,CNTNAP2,NDRG4 |
8.726e-03 | -4.74 | Toxicity of botulinum toxin type B (BoNT/B) | REACTOME pathways | R-HSA-5250958 | 3 | 1 | 10285 | 30 |
SYT1 |
8.726e-03 | -4.74 | Toxicity of botulinum toxin type G (BoNT/G) | REACTOME pathways | R-HSA-5250989 | 3 | 1 | 10285 | 30 |
SYT1 |
8.857e-03 | -4.73 | regeneration | biological process | GO:0031099 | 155 | 3 | 18204 | 50 |
CD9,GAP43,NFIB |
9.081e-03 | -4.70 | AK1 (adenylate kinase 1) | protein interactions | 203 | 57 | 2 | 19454 | 49 |
TXN,SNCA |
9.081e-03 | -4.70 | SPAST (spastin) | protein interactions | 6683 | 57 | 2 | 19454 | 49 |
RTN1,SNCA |
9.171e-03 | -4.69 | positive regulation of synaptic transmission | biological process | GO:0050806 | 157 | 3 | 18204 | 50 |
RELN,SNCA,SYT1 |
9.172e-03 | -4.69 | MAPT (microtubule associated protein tau) | protein interactions | 4137 | 948 | 7 | 19454 | 49 |
RTN1,RUFY3,COX5B,SNCA,SYT1,CEND1,CLU |
9.390e-03 | -4.67 | MANEA (mannosidase endo-alpha) | protein interactions | 79694 | 58 | 2 | 19454 | 49 |
OLFM1,CLU |
9.401e-03 | -4.67 | postsynaptic density | cellular component | GO:0014069 | 317 | 4 | 19108 | 50 |
GAP43,GNG3,PDE4B,RTN1 |
9.401e-03 | -4.67 | secretory granule membrane | cellular component | GO:0030667 | 317 | 4 | 19108 | 50 |
CD9,SNCA,SYT1,DYNC1LI1 |
9.586e-03 | -4.65 | NDUFV3 (NADH:ubiquinone oxidoreductase subunit V3) | protein interactions | 4731 | 174 | 3 | 19454 | 49 |
NDUFB2,NDUFA1,NDUFA5 |
9.975e-03 | -4.61 | positive regulation of protein localization | biological process | GO:1903829 | 480 | 5 | 18204 | 50 |
RUFY3,ACHE,OAZ1,C1QTNF3,SNCA |
1.001e-02 | -4.60 | regulation of amyloid precursor protein catabolic process | biological process | GO:1902991 | 55 | 2 | 18204 | 50 |
RTN1,CLU |
1.001e-02 | -4.60 | synaptic vesicle endocytosis | biological process | GO:0048488 | 55 | 2 | 18204 | 50 |
SYT1,SNCA |
1.002e-02 | -4.60 | clathrin binding | molecular function | GO:0030276 | 57 | 2 | 18094 | 48 |
SYT1,DNER |
1.002e-02 | -4.60 | COX1 (cytochrome c oxidase subunit I) | protein interactions | 4512 | 60 | 2 | 19454 | 49 |
SNCA,COX6A1 |
1.004e-02 | -4.60 | Ap2m1 (adaptor-related protein complex 2, mu 1 subunit) | protein interactions | 11773 | 4 | 1 | 19454 | 49 |
SNCA |
1.004e-02 | -4.60 | Actg1 (actin, gamma, cytoplasmic 1) | protein interactions | 11465 | 4 | 1 | 19454 | 49 |
SNCA |
1.004e-02 | -4.60 | Rps7 (ribosomal protein S7) | protein interactions | 20115 | 4 | 1 | 19454 | 49 |
SNCA |
1.004e-02 | -4.60 | UBP3 (mRNA-binding ubiquitin-specific protease UBP3) | protein interactions | 856895 | 4 | 1 | 19454 | 49 |
SNCA |
1.004e-02 | -4.60 | HES3 (hes family bHLH transcription factor 3) | protein interactions | 390992 | 4 | 1 | 19454 | 49 |
NRN1 |
1.004e-02 | -4.60 | Atp6v1a (ATPase, H+ transporting, lysosomal V1 subunit A) | protein interactions | 11964 | 4 | 1 | 19454 | 49 |
SNCA |
1.004e-02 | -4.60 | Slc25a3 (solute carrier family 25 (mitochondrial carrier, phosphate carrier), member 3) | protein interactions | 18674 | 4 | 1 | 19454 | 49 |
SNCA |
1.004e-02 | -4.60 | SSA1 (Hsp70 family ATPase SSA1) | protein interactions | 851259 | 4 | 1 | 19454 | 49 |
SNCA |
1.004e-02 | -4.60 | Capza2 (capping actin protein of muscle Z-line subunit alpha 2) | protein interactions | 12343 | 4 | 1 | 19454 | 49 |
SNCA |
1.004e-02 | -4.60 | GLT1D1 (glycosyltransferase 1 domain containing 1) | protein interactions | 144423 | 4 | 1 | 19454 | 49 |
RUFY3 |
1.004e-02 | -4.60 | Tubb6 (tubulin, beta 6 class V) | protein interactions | 67951 | 4 | 1 | 19454 | 49 |
SNCA |
1.004e-02 | -4.60 | Ppp1ca (protein phosphatase 1 catalytic subunit alpha) | protein interactions | 19045 | 4 | 1 | 19454 | 49 |
SNCA |
1.004e-02 | -4.60 | GRK2 (G protein-coupled receptor kinase 2) | protein interactions | 282682 | 4 | 1 | 19454 | 49 |
SNCA |
1.004e-02 | -4.60 | CHAC1 (ChaC glutathione specific gamma-glutamylcyclotransferase 1) | protein interactions | 79094 | 4 | 1 | 19454 | 49 |
SCG5 |
1.004e-02 | -4.60 | Aldoa (aldolase A, fructose-bisphosphate) | protein interactions | 11674 | 4 | 1 | 19454 | 49 |
SNCA |
1.004e-02 | -4.60 | WDR97 (WD repeat domain 97) | protein interactions | 340390 | 4 | 1 | 19454 | 49 |
DUSP23 |
1.004e-02 | -4.60 | Slc25a12 (solute carrier family 25 (mitochondrial carrier, Aralar), member 12) | protein interactions | 78830 | 4 | 1 | 19454 | 49 |
SNCA |
1.004e-02 | -4.60 | Map1b (microtubule-associated protein 1B) | protein interactions | 29456 | 4 | 1 | 19454 | 49 |
SNCA |
1.004e-02 | -4.60 | Map6 (microtubule-associated protein 6) | protein interactions | 17760 | 4 | 1 | 19454 | 49 |
SNCA |
1.004e-02 | -4.60 | Slc25a11 (solute carrier family 25 (mitochondrial carrier oxoglutarate carrier), member 11) | protein interactions | 67863 | 4 | 1 | 19454 | 49 |
SNCA |
1.004e-02 | -4.60 | Map2 (microtubule-associated protein 2) | protein interactions | 17756 | 4 | 1 | 19454 | 49 |
SNCA |
1.004e-02 | -4.60 | SLC6A2 (solute carrier family 6 member 2) | protein interactions | 6530 | 4 | 1 | 19454 | 49 |
SNCA |
1.004e-02 | -4.60 | PCSK2 (proprotein convertase subtilisin/kexin type 2) | protein interactions | 5126 | 4 | 1 | 19454 | 49 |
SCG5 |
1.004e-02 | -4.60 | PSY3 (Psy3p) | protein interactions | 851091 | 4 | 1 | 19454 | 49 |
SNCA |
1.004e-02 | -4.60 | Srgap2 (SLIT-ROBO Rho GTPase activating protein 2) | protein interactions | 14270 | 4 | 1 | 19454 | 49 |
SCOC |
1.015e-02 | -4.59 | receptor-mediated endocytosis | biological process | GO:0006898 | 163 | 3 | 18204 | 50 |
CD9,SNCA,ACHE |
1.036e-02 | -4.57 | vesicle docking | biological process | GO:0048278 | 56 | 2 | 18204 | 50 |
NDRG4,SYT1 |
1.036e-02 | -4.57 | presynaptic endocytosis | biological process | GO:0140238 | 56 | 2 | 18204 | 50 |
SYT1,SNCA |
1.038e-02 | -4.57 | positive regulation of secretion | biological process | GO:0051047 | 311 | 4 | 18204 | 50 |
SNCA,C1QTNF3,ACHE,SYT1 |
1.043e-02 | -4.56 | clathrin-sculpted glutamate transport vesicle | cellular component | GO:0060199 | 4 | 1 | 19108 | 50 |
SYT1 |
1.043e-02 | -4.56 | clathrin-sculpted glutamate transport vesicle membrane | cellular component | GO:0060203 | 4 | 1 | 19108 | 50 |
SYT1 |
1.043e-02 | -4.56 | insulin-like growth factor ternary complex | cellular component | GO:0042567 | 4 | 1 | 19108 | 50 |
IGFBP5 |
1.046e-02 | -4.56 | - | gene3d domains | 1.20.5.2480 | 4 | 1 | 14470 | 38 |
RTN1 |
1.054e-02 | -4.55 | PDE4_UCR | interpro domains | IPR040844 | 4 | 1 | 18521 | 49 |
PDE4B |
1.054e-02 | -4.55 | CTF/NFI | interpro domains | IPR000647 | 4 | 1 | 18521 | 49 |
NFIB |
1.054e-02 | -4.55 | CTF/NFI_DNA-bd_CS | interpro domains | IPR019739 | 4 | 1 | 18521 | 49 |
NFIB |
1.054e-02 | -4.55 | Glut_rich_SH3-bd | interpro domains | IPR006993 | 4 | 1 | 18521 | 49 |
SH3BGRL3 |
1.054e-02 | -4.55 | CTF/NFI_DNA-bd-dom | interpro domains | IPR020604 | 4 | 1 | 18521 | 49 |
NFIB |
1.054e-02 | -4.55 | RTN1-4 | interpro domains | IPR046964 | 4 | 1 | 18521 | 49 |
RTN1 |
1.054e-02 | -4.55 | CTF/NFI_DNA-bd_N | interpro domains | IPR019548 | 4 | 1 | 18521 | 49 |
NFIB |
1.054e-02 | -4.55 | Reticulon | interpro domains | IPR003388 | 4 | 1 | 18521 | 49 |
RTN1 |
1.054e-02 | -4.55 | NDRG | interpro domains | IPR004142 | 4 | 1 | 18521 | 49 |
NDRG4 |
1.054e-02 | -4.55 | WRNPLPNID | interpro domains | IPR033461 | 4 | 1 | 18521 | 49 |
MLLT11 |
1.057e-02 | -4.55 | calcium ion sensor activity | molecular function | GO:0061891 | 4 | 1 | 18094 | 48 |
SYT1 |
1.057e-02 | -4.55 | very-low-density lipoprotein particle receptor binding | molecular function | GO:0070326 | 4 | 1 | 18094 | 48 |
RELN |
1.057e-02 | -4.55 | H3K27me3 modified histone binding | molecular function | GO:0061628 | 4 | 1 | 18094 | 48 |
CHD5 |
1.067e-02 | -4.54 | DUSP28 (dual specificity phosphatase 28) | protein interactions | 285193 | 62 | 2 | 19454 | 49 |
TAGLN2,DUSP23 |
1.079e-02 | -4.53 | CTF_NFI_1 | prosite domains | PS00349 | 4 | 1 | 12186 | 33 |
NFIB |
1.079e-02 | -4.53 | RETICULON | prosite domains | PS50845 | 4 | 1 | 12186 | 33 |
RTN1 |
1.079e-02 | -4.53 | CTF_NFI_2 | prosite domains | PS51080 | 4 | 1 | 12186 | 33 |
NFIB |
1.082e-02 | -4.53 | positive regulation of cellular component organization | biological process | GO:0051130 | 1122 | 8 | 18204 | 50 |
RUFY3,CNTNAP2,CLU,SYT1,NDRG4,MLLT11,RELN,SNCA |
1.094e-02 | -4.52 | positive regulation of synaptic vesicle membrane organization | biological process | GO:1901634 | 4 | 1 | 18204 | 50 |
SYT1 |
1.094e-02 | -4.52 | positive regulation of inclusion body assembly | biological process | GO:0090261 | 4 | 1 | 18204 | 50 |
CLU |
1.094e-02 | -4.52 | regulation of hydrogen peroxide catabolic process | biological process | GO:2000295 | 4 | 1 | 18204 | 50 |
SNCA |
1.094e-02 | -4.52 | clustering of voltage-gated potassium channels | biological process | GO:0045163 | 4 | 1 | 18204 | 50 |
CNTNAP2 |
1.094e-02 | -4.52 | NMDA glutamate receptor clustering | biological process | GO:0097114 | 4 | 1 | 18204 | 50 |
RELN |
1.094e-02 | -4.52 | calcium-dependent activation of synaptic vesicle fusion | biological process | GO:0099502 | 4 | 1 | 18204 | 50 |
SYT1 |
1.094e-02 | -4.52 | myoblast fusion involved in skeletal muscle regeneration | biological process | GO:0014905 | 4 | 1 | 18204 | 50 |
CD9 |
1.094e-02 | -4.52 | trigeminal sensory nucleus development | biological process | GO:0021730 | 4 | 1 | 18204 | 50 |
NFIB |
1.094e-02 | -4.52 | club cell differentiation | biological process | GO:0060486 | 4 | 1 | 18204 | 50 |
NFIB |
1.094e-02 | -4.52 | positive regulation of synaptic vesicle fusion to presynaptic active zone membrane | biological process | GO:0031632 | 4 | 1 | 18204 | 50 |
SYT1 |
1.094e-02 | -4.52 | regulation of serotonin uptake | biological process | GO:0051611 | 4 | 1 | 18204 | 50 |
SNCA |
1.094e-02 | -4.52 | spinal cord motor neuron migration | biological process | GO:0097476 | 4 | 1 | 18204 | 50 |
RELN |
1.094e-02 | -4.52 | principal sensory nucleus of trigeminal nerve development | biological process | GO:0021740 | 4 | 1 | 18204 | 50 |
NFIB |
1.094e-02 | -4.52 | regulation of calcium ion-dependent exocytosis of neurotransmitter | biological process | GO:1903233 | 4 | 1 | 18204 | 50 |
SYT1 |
1.094e-02 | -4.52 | protein localization to juxtaparanode region of axon | biological process | GO:0071205 | 4 | 1 | 18204 | 50 |
CNTNAP2 |
1.094e-02 | -4.52 | positive regulation of AMPA receptor activity | biological process | GO:2000969 | 4 | 1 | 18204 | 50 |
RELN |
1.097e-02 | -4.51 | WRNPLPNID | pfam domains | PF15017 | 4 | 1 | 17795 | 49 |
MLLT11 |
1.097e-02 | -4.51 | PDE4_UCR | pfam domains | PF18100 | 4 | 1 | 17795 | 49 |
PDE4B |
1.097e-02 | -4.51 | CTF_NFI | pfam domains | PF00859 | 4 | 1 | 17795 | 49 |
NFIB |
1.097e-02 | -4.51 | NfI_DNAbd_pre-N | pfam domains | PF10524 | 4 | 1 | 17795 | 49 |
NFIB |
1.097e-02 | -4.51 | Reticulon | pfam domains | PF02453 | 4 | 1 | 17795 | 49 |
RTN1 |
1.097e-02 | -4.51 | Ndr | pfam domains | PF03096 | 4 | 1 | 17795 | 49 |
NDRG4 |
1.097e-02 | -4.51 | SH3BGR | pfam domains | PF04908 | 4 | 1 | 17795 | 49 |
SH3BGRL3 |
1.099e-02 | -4.51 | ASS1 (argininosuccinate synthase 1) | protein interactions | 445 | 183 | 3 | 19454 | 49 |
ETFB,TXN,TAGLN2 |
1.101e-02 | -4.51 | POLB (DNA polymerase beta) | protein interactions | 5423 | 63 | 2 | 19454 | 49 |
EMX2,SNCA |
1.101e-02 | -4.51 | C1qbp (complement component 1, q subcomponent binding protein) | protein interactions | 12261 | 63 | 2 | 19454 | 49 |
ETFB,COX5B |
1.107e-02 | -4.50 | inorganic molecular entity transmembrane transporter activity | molecular function | GO:0015318 | 714 | 6 | 18094 | 48 |
NDUFA5,UQCR10,NDUFA1,ATP6V0B,COX5B,NDUFB2 |
1.111e-02 | -4.50 | asymmetric synapse | cellular component | GO:0032279 | 333 | 4 | 19108 | 50 |
GAP43,PDE4B,RTN1,GNG3 |
1.120e-02 | -4.49 | modulation of chemical synaptic transmission | biological process | GO:0050804 | 494 | 5 | 18204 | 50 |
SNCA,RELN,CALB2,SYT1,ACHE |
1.129e-02 | -4.48 | regulation of trans-synaptic signaling | biological process | GO:0099177 | 495 | 5 | 18204 | 50 |
ACHE,SYT1,SNCA,RELN,CALB2 |
1.130e-02 | -4.48 | bone-humerus-other-chondroblastoma | COSMIC cancer mutations | bone-humerus-other-chondroblastoma | 301 | 4 | 16828 | 49 |
PCP4,CNTNAP2,CD9,THSD7A |
1.133e-02 | -4.48 | MRM1 (mitochondrial rRNA methyltransferase 1) | protein interactions | 79922 | 348 | 4 | 19454 | 49 |
MGST3,ETFB,NDUFA5,COX5B |
1.140e-02 | -4.47 | neuron projection development | biological process | GO:0031175 | 693 | 6 | 18204 | 50 |
RELN,GAP43,NFIB,NRN1,CNTNAP2,CCK |
1.144e-02 | -4.47 | DNAJA3 (DnaJ heat shock protein family (Hsp40) member A3) | protein interactions | 9093 | 349 | 4 | 19454 | 49 |
TXN,ETFB,COX5B,NDUFA5 |
1.148e-02 | -4.47 | NDUFA8 (NADH:ubiquinone oxidoreductase subunit A8) | protein interactions | 4702 | 186 | 3 | 19454 | 49 |
NDUFA5,NDUFB2,NDUFA1 |
1.166e-02 | -4.45 | endocytosis | biological process | GO:0006897 | 499 | 5 | 18204 | 50 |
CD9,SNCA,DNER,SYT1,ACHE |
1.167e-02 | -4.45 | organelle membrane | cellular component | GO:0031090 | 3742 | 17 | 19108 | 50 |
UQCR10,NDUFA5,CLU,NDUFB2,SEZ6L2,NDUFA1,RTN1,SYT1,MGST3,COX5B,NDRG4,SCOC,DYNC1LI1,COX6A1,ATP6V0B,SNCA,CD9 |
1.178e-02 | -4.44 | transferase activity, transferring alkyl or aryl (other than methyl) groups | molecular function | GO:0016765 | 62 | 2 | 18094 | 48 |
SH3BGRL3,MGST3 |
1.183e-02 | -4.44 | Synaptic vesicle cycle | KEGG pathways | hsa04721 | 63 | 2 | 7161 | 19 |
ATP6V0B,SYT1 |
1.183e-02 | -4.44 | Synaptic vesicle cycle | KEGG pathways | ko04721 | 63 | 2 | 7161 | 19 |
SYT1,ATP6V0B |
1.186e-02 | -4.43 | catalytic complex | cellular component | GO:1902494 | 1708 | 10 | 19108 | 50 |
CHD5,NDUFB2,DYNC1LI1,NDUFA5,UQCR10,COX5B,GNG3,NDUFA1,COX6A1,ATP6V0B |
1.193e-02 | -4.43 | positive regulation of establishment of protein localization | biological process | GO:1904951 | 324 | 4 | 18204 | 50 |
C1QTNF3,RUFY3,ACHE,OAZ1 |
1.198e-02 | -4.42 | PLEKHF2 (pleckstrin homology and FYVE domain containing 2) | protein interactions | 79666 | 189 | 3 | 19454 | 49 |
NDUFA5,COX5B,RTN1 |
1.203e-02 | -4.42 | MICB (MHC class I polypeptide-related sequence B) | protein interactions | 4277 | 66 | 2 | 19454 | 49 |
COX6A1,CLU |
1.220e-02 | -4.41 | negative regulation of G protein-coupled receptor signaling pathway | biological process | GO:0045744 | 61 | 2 | 18204 | 50 |
PDE4B,SNCA |
1.230e-02 | -4.40 | purine ribonucleoside triphosphate metabolic process | biological process | GO:0009205 | 175 | 3 | 18204 | 50 |
NDUFB2,NDUFA5,NDUFA1 |
1.253e-02 | -4.38 | postsynaptic specialization | cellular component | GO:0099572 | 345 | 4 | 19108 | 50 |
GNG3,RTN1,PDE4B,GAP43 |
1.253e-02 | -4.38 | TLG2 (Tlg2p) | protein interactions | 854142 | 5 | 1 | 19454 | 49 |
SNCA |
1.253e-02 | -4.38 | Gnb2 (guanine nucleotide binding protein (G protein), beta 2) | protein interactions | 14693 | 5 | 1 | 19454 | 49 |
SNCA |
1.253e-02 | -4.38 | PKD1L1 (polycystin 1 like 1, transient receptor potential channel interacting) | protein interactions | 168507 | 5 | 1 | 19454 | 49 |
DYNC1LI1 |
1.253e-02 | -4.38 | Stxbp1 (syntaxin binding protein 1) | protein interactions | 20910 | 5 | 1 | 19454 | 49 |
SNCA |
1.253e-02 | -4.38 | ORF17 (ORF17) | protein interactions | 4961478 | 5 | 1 | 19454 | 49 |
SCOC |
1.253e-02 | -4.38 | ADCYAP1R1 (ADCYAP receptor type I) | protein interactions | 117 | 5 | 1 | 19454 | 49 |
CLU |
1.253e-02 | -4.38 | EPPIN (epididymal peptidase inhibitor) | protein interactions | 57119 | 5 | 1 | 19454 | 49 |
CLU |
1.253e-02 | -4.38 | GPA1 (guanine nucleotide-binding protein subunit alpha) | protein interactions | 856394 | 5 | 1 | 19454 | 49 |
SNCA |
1.253e-02 | -4.38 | Ncam1 (neural cell adhesion molecule 1) | protein interactions | 24586 | 5 | 1 | 19454 | 49 |
SNCA |
1.253e-02 | -4.38 | Rab8a (RAB8A, member RAS oncogene family) | protein interactions | 17274 | 5 | 1 | 19454 | 49 |
SNCA |
1.259e-02 | -4.38 | macrophage activation | biological process | GO:0042116 | 62 | 2 | 18204 | 50 |
CLU,SNCA |
1.261e-02 | -4.37 | EGF | smart domains | SM00181 | 184 | 3 | 9717 | 26 |
DNER,RELN,CNTNAP2 |
1.268e-02 | -4.37 | PHIP (pleckstrin homology domain interacting protein) | protein interactions | 55023 | 193 | 3 | 19454 | 49 |
CHD5,CLU,SNCA |
1.274e-02 | -4.36 | TSPAN2 (tetraspanin 2) | protein interactions | 10100 | 68 | 2 | 19454 | 49 |
MGST3,CD9 |
1.274e-02 | -4.36 | GJB5 (gap junction protein beta 5) | protein interactions | 2709 | 68 | 2 | 19454 | 49 |
CLU,IGFBP5 |
1.274e-02 | -4.36 | NRM (nurim) | protein interactions | 11270 | 68 | 2 | 19454 | 49 |
MGST3,ATP6V0B |
1.298e-02 | -4.34 | synaptic vesicle exocytosis | biological process | GO:0016079 | 63 | 2 | 18204 | 50 |
SNCA,SYT1 |
1.298e-02 | -4.34 | synaptic vesicle recycling | biological process | GO:0036465 | 63 | 2 | 18204 | 50 |
SYT1,SNCA |
1.302e-02 | -4.34 | neurofibrillary tangle | cellular component | GO:0097418 | 5 | 1 | 19108 | 50 |
CLU |
1.302e-02 | -4.34 | insulin-like growth factor binding protein complex | cellular component | GO:0016942 | 5 | 1 | 19108 | 50 |
IGFBP5 |
1.302e-02 | -4.34 | clathrin-sculpted monoamine transport vesicle membrane | cellular component | GO:0070083 | 5 | 1 | 19108 | 50 |
SYT1 |
1.302e-02 | -4.34 | clathrin-sculpted monoamine transport vesicle | cellular component | GO:0070081 | 5 | 1 | 19108 | 50 |
SYT1 |
1.302e-02 | -4.34 | endocytic vesicle | cellular component | GO:0030139 | 349 | 4 | 19108 | 50 |
DYNC1LI1,ATP6V0B,CD9,SYT1 |
1.310e-02 | -4.34 | TIGD5 (tigger transposable element derived 5) | protein interactions | 84948 | 69 | 2 | 19454 | 49 |
SPINT2,GAP43 |
1.316e-02 | -4.33 | F/V-ATP_Csub_sf | interpro domains | IPR035921 | 5 | 1 | 18521 | 49 |
ATP6V0B |
1.316e-02 | -4.33 | ATPase_proteolipid_c-like_dom | interpro domains | IPR002379 | 5 | 1 | 18521 | 49 |
ATP6V0B |
1.316e-02 | -4.33 | TAL-like | interpro domains | IPR040238 | 5 | 1 | 18521 | 49 |
NHLH2 |
1.316e-02 | -4.33 | Mab-21-like_nuc_Trfase | interpro domains | IPR046903 | 5 | 1 | 18521 | 49 |
MAB21L1 |
1.316e-02 | -4.33 | EGF_Tenascin | interpro domains | IPR041161 | 5 | 1 | 18521 | 49 |
RELN |
1.316e-02 | -4.33 | Sialidase_sf | interpro domains | IPR036278 | 5 | 1 | 18521 | 49 |
RELN |
1.320e-02 | -4.33 | metal ion sensor activity | molecular function | GO:0140784 | 5 | 1 | 18094 | 48 |
SYT1 |
1.320e-02 | -4.33 | ornithine decarboxylase regulator activity | molecular function | GO:0042979 | 5 | 1 | 18094 | 48 |
OAZ1 |
1.320e-02 | -4.33 | leukotriene-C4 synthase activity | molecular function | GO:0004464 | 5 | 1 | 18094 | 48 |
MGST3 |
1.320e-02 | -4.33 | ubiquinol-cytochrome-c reductase activity | molecular function | GO:0008121 | 5 | 1 | 18094 | 48 |
UQCR10 |
1.321e-02 | -4.33 | DNAJC19 (DnaJ heat shock protein family (Hsp40) member C19) | protein interactions | 131118 | 196 | 3 | 19454 | 49 |
NDUFA5,COX5B,ETFB |
1.326e-02 | -4.32 | purine ribonucleotide biosynthetic process | biological process | GO:0009152 | 180 | 3 | 18204 | 50 |
NDUFB2,NDUFA5,NDUFA1 |
1.332e-02 | -4.32 | regulation of vesicle-mediated transport | biological process | GO:0060627 | 516 | 5 | 18204 | 50 |
DYNC1LI1,SNCA,CLU,SYT1,NDRG4 |
1.346e-02 | -4.31 | Dynll1 (dynein light chain LC8-type 1) | protein interactions | 56455 | 70 | 2 | 19454 | 49 |
SNCA,DYNC1LI1 |
1.346e-02 | -4.31 | PGAM2 (phosphoglycerate mutase 2) | protein interactions | 5224 | 70 | 2 | 19454 | 49 |
TXN,DYNC1LI1 |
1.346e-02 | -4.31 | MTMR9 (myotubularin related protein 9) | protein interactions | 66036 | 70 | 2 | 19454 | 49 |
DYNC1LI1,CLU |
1.366e-02 | -4.29 | ribonucleoside triphosphate metabolic process | biological process | GO:0009199 | 182 | 3 | 18204 | 50 |
NDUFB2,NDUFA5,NDUFA1 |
1.366e-02 | -4.29 | purine nucleoside triphosphate metabolic process | biological process | GO:0009144 | 182 | 3 | 18204 | 50 |
NDUFB2,NDUFA1,NDUFA5 |
1.366e-02 | -4.29 | endoplasmic reticulum tubular network formation | biological process | GO:0071787 | 5 | 1 | 18204 | 50 |
RTN1 |
1.366e-02 | -4.29 | early endosome to recycling endosome transport | biological process | GO:0061502 | 5 | 1 | 18204 | 50 |
DYNC1LI1 |
1.366e-02 | -4.29 | hindbrain maturation | biological process | GO:0021578 | 5 | 1 | 18204 | 50 |
CEND1 |
1.366e-02 | -4.29 | negative regulation of adenylate cyclase-activating adrenergic receptor signaling pathway | biological process | GO:0071878 | 5 | 1 | 18204 | 50 |
PDE4B |
1.366e-02 | -4.29 | tube lumen cavitation | biological process | GO:0060605 | 5 | 1 | 18204 | 50 |
NFIB |
1.366e-02 | -4.29 | central nervous system myelin maintenance | biological process | GO:0032286 | 5 | 1 | 18204 | 50 |
CLU |
1.366e-02 | -4.29 | salivary gland cavitation | biological process | GO:0060662 | 5 | 1 | 18204 | 50 |
NFIB |
1.366e-02 | -4.29 | positive regulation of amyloid fibril formation | biological process | GO:1905908 | 5 | 1 | 18204 | 50 |
CLU |
1.366e-02 | -4.29 | regulation of acyl-CoA biosynthetic process | biological process | GO:0050812 | 5 | 1 | 18204 | 50 |
SNCA |
1.366e-02 | -4.29 | regulation of polyamine transmembrane transport | biological process | GO:1902267 | 5 | 1 | 18204 | 50 |
OAZ1 |
1.369e-02 | -4.29 | EGF_Tenascin | pfam domains | PF18720 | 5 | 1 | 17795 | 49 |
RELN |
1.369e-02 | -4.29 | ATP-synt_C | pfam domains | PF00137 | 5 | 1 | 17795 | 49 |
ATP6V0B |
1.369e-02 | -4.29 | Mab-21 | pfam domains | PF03281 | 5 | 1 | 17795 | 49 |
MAB21L1 |
1.377e-02 | -4.29 | long-term synaptic potentiation | biological process | GO:0060291 | 65 | 2 | 18204 | 50 |
SNCA,RELN |
1.377e-02 | -4.29 | tissue regeneration | biological process | GO:0042246 | 65 | 2 | 18204 | 50 |
CD9,GAP43 |
1.377e-02 | -4.29 | forebrain cell migration | biological process | GO:0021885 | 65 | 2 | 18204 | 50 |
RELN,EMX2 |
1.391e-02 | -4.27 | cell projection membrane | cellular component | GO:0031253 | 356 | 4 | 19108 | 50 |
NDRG4,GAP43,CNTNAP2,SH3BGRL3 |
1.403e-02 | -4.27 | monoatomic ion transmembrane transporter activity | molecular function | GO:0015075 | 752 | 6 | 18094 | 48 |
NDUFB2,COX5B,ATP6V0B,UQCR10,NDUFA1,NDUFA5 |
1.427e-02 | -4.25 | positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction | biological process | GO:0051897 | 185 | 3 | 18204 | 50 |
TXN,IGFBP5,RELN |
1.450e-02 | -4.23 | Sperm:Oocyte Membrane Binding | REACTOME pathways | R-HSA-1300652 | 5 | 1 | 10285 | 30 |
CD9 |
1.450e-02 | -4.23 | Signaling by MST1 | REACTOME pathways | R-HSA-8852405 | 5 | 1 | 10285 | 30 |
SPINT2 |
1.450e-02 | -4.23 | Reelin signalling pathway | REACTOME pathways | R-HSA-8866376 | 5 | 1 | 10285 | 30 |
RELN |
1.458e-02 | -4.23 | ABAT (4-aminobutyrate aminotransferase) | protein interactions | 18 | 73 | 2 | 19454 | 49 |
SNCA,ETFB |
1.481e-02 | -4.21 | regulation of establishment of protein localization | biological process | GO:0070201 | 530 | 5 | 18204 | 50 |
C1QTNF3,TXN,OAZ1,ACHE,RUFY3 |
1.496e-02 | -4.20 | THAP4 (THAP domain containing 4) | protein interactions | 51078 | 74 | 2 | 19454 | 49 |
NDRG4,IGFBP5 |
1.496e-02 | -4.20 | CHCHD10 (coiled-coil-helix-coiled-coil-helix domain containing 10) | protein interactions | 400916 | 74 | 2 | 19454 | 49 |
NDUFA5,COX6A1 |
1.496e-02 | -4.20 | ARL6IP6 (ADP ribosylation factor like GTPase 6 interacting protein 6) | protein interactions | 151188 | 74 | 2 | 19454 | 49 |
SPINT2,MGST3 |
1.496e-02 | -4.20 | GIMAP5 (GTPase, IMAP family member 5) | protein interactions | 55340 | 74 | 2 | 19454 | 49 |
SYT1,MGST3 |
1.502e-02 | -4.20 | PAPPA2 (pappalysin 2) | protein interactions | 60676 | 6 | 1 | 19454 | 49 |
IGFBP5 |
1.502e-02 | -4.20 | Map1b (microtubule-associated protein 1B) | protein interactions | 17755 | 6 | 1 | 19454 | 49 |
SNCA |
1.502e-02 | -4.20 | TRMT9B (tRNA methyltransferase 9B (putative)) | protein interactions | 57604 | 6 | 1 | 19454 | 49 |
RUFY3 |
1.502e-02 | -4.20 | CLDN6 (claudin 6) | protein interactions | 9074 | 6 | 1 | 19454 | 49 |
IGFBP5 |
1.502e-02 | -4.20 | CDC5 (polo kinase CDC5) | protein interactions | 855013 | 6 | 1 | 19454 | 49 |
SNCA |
1.502e-02 | -4.20 | Taok2 (TAO kinase 2) | protein interactions | 381921 | 6 | 1 | 19454 | 49 |
CLU |
1.502e-02 | -4.20 | HRD1 (E3 ubiquitin-protein ligase HRD1) | protein interactions | 854149 | 6 | 1 | 19454 | 49 |
SNCA |
1.502e-02 | -4.20 | Ap1b1 (adaptor protein complex AP-1, beta 1 subunit) | protein interactions | 11764 | 6 | 1 | 19454 | 49 |
SNCA |
1.502e-02 | -4.20 | Vdac2 (voltage-dependent anion channel 2) | protein interactions | 22334 | 6 | 1 | 19454 | 49 |
SNCA |
1.502e-02 | -4.20 | Sptbn1 (spectrin beta, non-erythrocytic 1) | protein interactions | 20742 | 6 | 1 | 19454 | 49 |
SNCA |
1.517e-02 | -4.19 | breast-carcinoma-ductal_carcinoma | COSMIC cancer mutations | breast-carcinoma-ductal_carcinoma | 14824 | 48 | 16828 | 49 |
OAZ1,DYNC1LI1,SH3BGRL3,RELN,IGFBP5,OLFM1,ETFB,CCK,EMX2,NHLH2,MAB21L1,CALB2,CLU,TAGLN2,SEZ6L2,CHD5,COX6A1,DUSP23,SCOC,ATP6V0B,UQCR10,C1QTNF3,NDUFB2,CNTNAP2,CD9,SNCA,NDUFA1,PDE4B,RUFY3,SCG5,GNG3,MGST3,DNER,TXN,NRN1,ISOC1,SYT1,GAP43,PCP4,NFIB,NDUFA5,CEND1,ACHE,SPINT2,THSD7A,NDRG4,RTN1,COX5B |
1.524e-02 | -4.18 | phosphatidylserine binding | molecular function | GO:0001786 | 71 | 2 | 18094 | 48 |
SYT1,GAP43 |
1.526e-02 | -4.18 | inclusion body | cellular component | GO:0016234 | 72 | 2 | 19108 | 50 |
CLU,SNCA |
1.528e-02 | -4.18 | ZFP36L2 (ZFP36 ring finger protein like 2) | protein interactions | 678 | 207 | 3 | 19454 | 49 |
MAB21L1,TXN,TAGLN2 |
1.531e-02 | -4.18 | pallium development | biological process | GO:0021543 | 190 | 3 | 18204 | 50 |
CNTNAP2,RELN,EMX2 |
1.547e-02 | -4.17 | BCL2L1 (BCL2 like 1) | protein interactions | 598 | 208 | 3 | 19454 | 49 |
SNCA,RTN1,CLU |
1.561e-02 | -4.16 | anatomical structure formation involved in morphogenesis | biological process | GO:0048646 | 964 | 7 | 18204 | 50 |
THSD7A,RELN,SPINT2,NFIB,OLFM1,CD9,CEND1 |
1.566e-02 | -4.16 | Membrane associated eicosanoid/glutathione metabolism-like domain | gene3d domains | 1.20.120.550 | 6 | 1 | 14470 | 38 |
MGST3 |
1.569e-02 | -4.16 | EGF_3 | prosite domains | PS50026 | 196 | 3 | 12186 | 33 |
DNER,CNTNAP2,RELN |
1.577e-02 | -4.15 | Calponin_repeat | interpro domains | IPR000557 | 6 | 1 | 18521 | 49 |
TAGLN2 |
1.577e-02 | -4.15 | Membr-assoc_MAPEG | interpro domains | IPR001129 | 6 | 1 | 18521 | 49 |
MGST3 |
1.577e-02 | -4.15 | IGFBP_1-6_chordata | interpro domains | IPR022321 | 6 | 1 | 18521 | 49 |
IGFBP5 |
1.577e-02 | -4.15 | MAPEG-like_dom_sf | interpro domains | IPR023352 | 6 | 1 | 18521 | 49 |
MGST3 |
1.577e-02 | -4.15 | TSP1_spondin_dom | interpro domains | IPR044004 | 6 | 1 | 18521 | 49 |
THSD7A |
1.585e-02 | -4.14 | negative regulation of smooth muscle cell proliferation | biological process | GO:0048662 | 70 | 2 | 18204 | 50 |
IGFBP5,NDRG4 |
1.594e-02 | -4.14 | cell development | biological process | GO:0048468 | 2236 | 12 | 18204 | 50 |
CCK,CLU,CHD5,SPINT2,RELN,CNTNAP2,NRN1,DNER,ACHE,NHLH2,NFIB,GAP43 |
1.613e-02 | -4.13 | Rmdn3 (regulator of microtubule dynamics 3) | protein interactions | 67809 | 77 | 2 | 19454 | 49 |
MGST3,SNCA |
1.613e-02 | -4.13 | GPX1 (glutathione peroxidase 1) | protein interactions | 2876 | 77 | 2 | 19454 | 49 |
IGFBP5,TXN |
1.613e-02 | -4.13 | FKBP2 (FKBP prolyl isomerase 2) | protein interactions | 2286 | 77 | 2 | 19454 | 49 |
TAGLN2,TXN |
1.613e-02 | -4.13 | Htt (huntingtin) | protein interactions | 15194 | 77 | 2 | 19454 | 49 |
COX5B,COX6A1 |
1.614e-02 | -4.13 | CALPONIN_1 | prosite domains | PS01052 | 6 | 1 | 12186 | 33 |
TAGLN2 |
1.614e-02 | -4.13 | CALPONIN_2 | prosite domains | PS51122 | 6 | 1 | 12186 | 33 |
TAGLN2 |
1.616e-02 | -4.13 | bone-femur-other-chondroblastoma | COSMIC cancer mutations | bone-femur-other-chondroblastoma | 183 | 3 | 16828 | 49 |
SYT1,ETFB,CNTNAP2 |
1.619e-02 | -4.12 | presynapse | cellular component | GO:0098793 | 569 | 5 | 19108 | 50 |
SYT1,SNCA,CALB2,GAP43,PDE4B |
1.627e-02 | -4.12 | coated vesicle membrane | cellular component | GO:0030662 | 204 | 3 | 19108 | 50 |
CD9,SYT1,ATP6V0B |
1.628e-02 | -4.12 | organelle envelope | cellular component | GO:0031967 | 1267 | 8 | 19108 | 50 |
COX5B,MGST3,NDUFA1,COX6A1,NDUFB2,CLU,NDUFA5,UQCR10 |
1.637e-02 | -4.11 | negative regulation of protein export from nucleus | biological process | GO:0046826 | 6 | 1 | 18204 | 50 |
TXN |
1.637e-02 | -4.11 | protein targeting to vacuole involved in autophagy | biological process | GO:0071211 | 6 | 1 | 18204 | 50 |
CLU |
1.637e-02 | -4.11 | cerebral cortex tangential migration | biological process | GO:0021800 | 6 | 1 | 18204 | 50 |
RELN |
1.637e-02 | -4.11 | acetate ester metabolic process | biological process | GO:1900619 | 6 | 1 | 18204 | 50 |
ACHE |
1.637e-02 | -4.11 | regulation of relaxation of cardiac muscle | biological process | GO:1901897 | 6 | 1 | 18204 | 50 |
PDE4B |
1.637e-02 | -4.11 | response to iron(II) ion | biological process | GO:0010040 | 6 | 1 | 18204 | 50 |
SNCA |
1.637e-02 | -4.11 | regulation of mitochondrial electron transport, NADH to ubiquinone | biological process | GO:1902956 | 6 | 1 | 18204 | 50 |
SNCA |
1.637e-02 | -4.11 | imitative learning | biological process | GO:0098596 | 6 | 1 | 18204 | 50 |
CNTNAP2 |
1.637e-02 | -4.11 | postsynaptic density protein 95 clustering | biological process | GO:0097119 | 6 | 1 | 18204 | 50 |
RELN |
1.637e-02 | -4.11 | vocal learning | biological process | GO:0042297 | 6 | 1 | 18204 | 50 |
CNTNAP2 |
1.637e-02 | -4.11 | paranodal junction assembly | biological process | GO:0030913 | 6 | 1 | 18204 | 50 |
CD9 |
1.637e-02 | -4.11 | negative regulation of monocyte chemotactic protein-1 production | biological process | GO:0071638 | 6 | 1 | 18204 | 50 |
C1QTNF3 |
1.637e-02 | -4.11 | dopamine uptake involved in synaptic transmission | biological process | GO:0051583 | 6 | 1 | 18204 | 50 |
SNCA |
1.637e-02 | -4.11 | type II pneumocyte differentiation | biological process | GO:0060510 | 6 | 1 | 18204 | 50 |
NFIB |
1.637e-02 | -4.11 | neuronal signal transduction | biological process | GO:0023041 | 6 | 1 | 18204 | 50 |
OLFM1 |
1.637e-02 | -4.11 | catecholamine uptake involved in synaptic transmission | biological process | GO:0051934 | 6 | 1 | 18204 | 50 |
SNCA |
1.637e-02 | -4.11 | positive regulation of hydrogen peroxide metabolic process | biological process | GO:0010726 | 6 | 1 | 18204 | 50 |
SNCA |
1.637e-02 | -4.11 | positive regulation of dopamine secretion | biological process | GO:0033603 | 6 | 1 | 18204 | 50 |
SYT1 |
1.637e-02 | -4.11 | male mating behavior | biological process | GO:0060179 | 6 | 1 | 18204 | 50 |
NHLH2 |
1.637e-02 | -4.11 | acetylcholine metabolic process | biological process | GO:0008291 | 6 | 1 | 18204 | 50 |
ACHE |
1.640e-02 | -4.11 | ribonucleotide biosynthetic process | biological process | GO:0009260 | 195 | 3 | 18204 | 50 |
NDUFA1,NDUFA5,NDUFB2 |
1.641e-02 | -4.11 | TSP1_spondin | pfam domains | PF19028 | 6 | 1 | 17795 | 49 |
THSD7A |
1.641e-02 | -4.11 | MAPEG | pfam domains | PF01124 | 6 | 1 | 17795 | 49 |
MGST3 |
1.641e-02 | -4.11 | Calponin | pfam domains | PF00402 | 6 | 1 | 17795 | 49 |
TAGLN2 |
1.648e-02 | -4.11 | SIAH1 (siah E3 ubiquitin protein ligase 1) | protein interactions | 6477 | 213 | 3 | 19454 | 49 |
SNCA,TXN,MAB21L1 |
1.649e-02 | -4.11 | clathrin-coated endocytic vesicle membrane | cellular component | GO:0030669 | 75 | 2 | 19108 | 50 |
SYT1,CD9 |
1.652e-02 | -4.10 | LRP8 (LDL receptor related protein 8) | protein interactions | 7804 | 78 | 2 | 19454 | 49 |
CLU,RELN |
1.652e-02 | -4.10 | GLOD4 (glyoxalase domain containing 4) | protein interactions | 51031 | 78 | 2 | 19454 | 49 |
SNCA,TXN |
1.652e-02 | -4.10 | NBEA (neurobeachin) | protein interactions | 26960 | 78 | 2 | 19454 | 49 |
IGFBP5,SNCA |
1.685e-02 | -4.08 | locomotory behavior | biological process | GO:0007626 | 197 | 3 | 18204 | 50 |
CEND1,RELN,SNCA |
1.693e-02 | -4.08 | DNAJB8 (DnaJ heat shock protein family (Hsp40) member B8) | protein interactions | 165721 | 79 | 2 | 19454 | 49 |
NDUFA5,MLLT11 |
1.708e-02 | -4.07 | nucleoside triphosphate metabolic process | biological process | GO:0009141 | 198 | 3 | 18204 | 50 |
NDUFA1,NDUFA5,NDUFB2 |
1.710e-02 | -4.07 | IGFBPFAMILY | prints domains | PR01976 | 6 | 1 | 5227 | 15 |
IGFBP5 |
1.721e-02 | -4.06 | regulation of cellular localization | biological process | GO:0060341 | 983 | 7 | 18204 | 50 |
SNCA,ACHE,TXN,NDRG4,C1QTNF3,RUFY3,OAZ1 |
1.725e-02 | -4.06 | regulation of secretion by cell | biological process | GO:1903530 | 551 | 5 | 18204 | 50 |
SYT1,ACHE,SCG5,C1QTNF3,SNCA |
1.728e-02 | -4.06 | calmodulin binding | molecular function | GO:0005516 | 206 | 3 | 18094 | 48 |
SYT1,PCP4,GAP43 |
1.738e-02 | -4.05 | Uptake and function of diphtheria toxin | REACTOME pathways | R-HSA-5336415 | 6 | 1 | 10285 | 30 |
CD9 |
1.738e-02 | -4.05 | MET Receptor Activation | REACTOME pathways | R-HSA-6806942 | 6 | 1 | 10285 | 30 |
SPINT2 |
1.738e-02 | -4.05 | Protein repair | REACTOME pathways | R-HSA-5676934 | 6 | 1 | 10285 | 30 |
TXN |
1.750e-02 | -4.05 | CCDC39 (coiled-coil domain 39 molecular ruler complex subunit) | protein interactions | 339829 | 7 | 1 | 19454 | 49 |
DYNC1LI1 |
1.750e-02 | -4.05 | C8B (complement C8 beta chain) | protein interactions | 732 | 7 | 1 | 19454 | 49 |
CLU |
1.750e-02 | -4.05 | Sptan1 (spectrin alpha, non-erythrocytic 1) | protein interactions | 20740 | 7 | 1 | 19454 | 49 |
SNCA |
1.750e-02 | -4.05 | PMP2 (peripheral myelin protein 2) | protein interactions | 5375 | 7 | 1 | 19454 | 49 |
TAGLN2 |
1.750e-02 | -4.05 | Tubb3 (tubulin, beta 3 class III) | protein interactions | 22152 | 7 | 1 | 19454 | 49 |
SNCA |
1.750e-02 | -4.05 | Dync1i2 (dynein cytoplasmic 1 intermediate chain 2) | protein interactions | 13427 | 7 | 1 | 19454 | 49 |
DYNC1LI1 |
1.750e-02 | -4.05 | Calm1 (calmodulin 1) | protein interactions | 12313 | 7 | 1 | 19454 | 49 |
SNCA |
1.750e-02 | -4.05 | SPOCK3 (SPARC (osteonectin), cwcv and kazal like domains proteoglycan 3) | protein interactions | 50859 | 7 | 1 | 19454 | 49 |
SNCA |
1.750e-02 | -4.05 | CYP4F8 (cytochrome P450 family 4 subfamily F member 8) | protein interactions | 11283 | 7 | 1 | 19454 | 49 |
CLU |
1.750e-02 | -4.05 | SOAT2 (sterol O-acyltransferase 2) | protein interactions | 8435 | 7 | 1 | 19454 | 49 |
CLU |
1.750e-02 | -4.05 | Iffo1 (intermediate filament family orphan 1) | protein interactions | 320678 | 7 | 1 | 19454 | 49 |
TAGLN2 |
1.750e-02 | -4.05 | SV2B (synaptic vesicle glycoprotein 2B) | protein interactions | 9899 | 7 | 1 | 19454 | 49 |
SYT1 |
1.750e-02 | -4.05 | Hnrnpa2b1 (heterogeneous nuclear ribonucleoprotein A2/B1) | protein interactions | 53379 | 7 | 1 | 19454 | 49 |
SNCA |
1.750e-02 | -4.05 | Tubb4a (tubulin, beta 4A class IVA) | protein interactions | 22153 | 7 | 1 | 19454 | 49 |
SNCA |
1.750e-02 | -4.05 | PROKR2 (prokineticin receptor 2) | protein interactions | 128674 | 7 | 1 | 19454 | 49 |
IGFBP5 |
1.750e-02 | -4.05 | C7 (complement C7) | protein interactions | 730 | 7 | 1 | 19454 | 49 |
CLU |
1.752e-02 | -4.04 | CCDC90B (coiled-coil domain containing 90B) | protein interactions | 60492 | 218 | 3 | 19454 | 49 |
NDUFA5,COX5B,ETFB |
1.761e-02 | -4.04 | organelle localization by membrane tethering | biological process | GO:0140056 | 74 | 2 | 18204 | 50 |
NDRG4,SYT1 |
1.774e-02 | -4.03 | GRIP1 (glutamate receptor interacting protein 1) | protein interactions | 23426 | 81 | 2 | 19454 | 49 |
SNCA,DYNC1LI1 |
1.789e-02 | -4.02 | PROKAR_LIPOPROTEIN | prosite domains | PS51257 | 76 | 2 | 12186 | 33 |
CNTNAP2,SEZ6L2 |
1.790e-02 | -4.02 | axonogenesis | biological process | GO:0007409 | 366 | 4 | 18204 | 50 |
RELN,GAP43,CCK,NFIB |
1.794e-02 | -4.02 | SLC25A12 (solute carrier family 25 member 12) | protein interactions | 8604 | 220 | 3 | 19454 | 49 |
COX6A1,NDUFA5,COX5B |
1.794e-02 | -4.02 | HSPA4L (heat shock protein family A (Hsp70) member 4 like) | protein interactions | 22824 | 220 | 3 | 19454 | 49 |
DYNC1LI1,SNCA,TAGLN2 |
1.800e-02 | -4.02 | ribose phosphate biosynthetic process | biological process | GO:0046390 | 202 | 3 | 18204 | 50 |
NDUFB2,NDUFA1,NDUFA5 |
1.804e-02 | -4.01 | membrane | cellular component | GO:0016020 | 9220 | 32 | 19108 | 50 |
RELN,DNER,PDE4B,RTN1,GAP43,COX5B,THSD7A,NDUFA5,SEZ6L2,GNG3,ATP6V0B,COX6A1,CD9,NRN1,C1QTNF3,SNCA,DYNC1LI1,NDRG4,SCOC,SPINT2,CHD5,NDUFA1,RUFY3,MGST3,SYT1,ACHE,CLU,CNTNAP2,UQCR10,SH3BGRL3,CEND1,NDUFB2 |
1.818e-02 | -4.01 | cerebellar mossy fiber | cellular component | GO:0044300 | 7 | 1 | 19108 | 50 |
NFIB |
1.843e-02 | -3.99 | thioredoxin-disulfide reductase (NADPH) activity | molecular function | GO:0004791 | 7 | 1 | 18094 | 48 |
TXN |
1.852e-02 | -3.99 | positive regulation of exocytosis | biological process | GO:0045921 | 76 | 2 | 18204 | 50 |
SNCA,SYT1 |
1.852e-02 | -3.99 | myotube differentiation | biological process | GO:0014902 | 76 | 2 | 18204 | 50 |
DNER,CD9 |
1.852e-02 | -3.99 | regulation of axon extension | biological process | GO:0030516 | 76 | 2 | 18204 | 50 |
OLFM1,RUFY3 |
1.858e-02 | -3.99 | PEPD (peptidase D) | protein interactions | 5184 | 83 | 2 | 19454 | 49 |
SNCA,TXN |
1.858e-02 | -3.99 | SERPINB8 (serpin family B member 8) | protein interactions | 5271 | 83 | 2 | 19454 | 49 |
EMX2,NHLH2 |
1.884e-02 | -3.97 | Oxidative phosphorylation | WikiPathways | WP623 | 54 | 2 | 5310 | 21 |
NDUFA5,NDUFB2 |
1.898e-02 | -3.96 | regulation of synaptic transmission, glutamatergic | biological process | GO:0051966 | 77 | 2 | 18204 | 50 |
SYT1,RELN |
1.900e-02 | -3.96 | MTAP (methylthioadenosine phosphorylase) | protein interactions | 4507 | 84 | 2 | 19454 | 49 |
DYNC1LI1,TAGLN2 |
1.904e-02 | -3.96 | NDUFS6 (NADH:ubiquinone oxidoreductase subunit S6) | protein interactions | 4726 | 225 | 3 | 19454 | 49 |
NDUFA5,COX5B,NDUFA1 |
1.904e-02 | -3.96 | CLUAP1 (clusterin associated protein 1) | protein interactions | 23059 | 225 | 3 | 19454 | 49 |
MGST3,CLU,SCOC |
1.905e-02 | -3.96 | purine ribonucleotide metabolic process | biological process | GO:0009150 | 373 | 4 | 18204 | 50 |
NDUFB2,PDE4B,NDUFA5,NDUFA1 |
1.907e-02 | -3.96 | regulation of epithelial cell proliferation involved in lung morphogenesis | biological process | GO:2000794 | 7 | 1 | 18204 | 50 |
NFIB |
1.907e-02 | -3.96 | chaperone-mediated autophagy | biological process | GO:0061684 | 7 | 1 | 18204 | 50 |
CLU |
1.907e-02 | -3.96 | regulation of adiponectin secretion | biological process | GO:0070163 | 7 | 1 | 18204 | 50 |
C1QTNF3 |
1.907e-02 | -3.96 | regulation of mitochondrial ATP synthesis coupled electron transport | biological process | GO:1905446 | 7 | 1 | 18204 | 50 |
SNCA |
1.907e-02 | -3.96 | ureter morphogenesis | biological process | GO:0072197 | 7 | 1 | 18204 | 50 |
EMX2 |
1.907e-02 | -3.96 | spontaneous neurotransmitter secretion | biological process | GO:0061669 | 7 | 1 | 18204 | 50 |
SYT1 |
1.907e-02 | -3.96 | cerebral cortex regionalization | biological process | GO:0021796 | 7 | 1 | 18204 | 50 |
EMX2 |
1.907e-02 | -3.96 | negative regulation of mesenchymal cell proliferation | biological process | GO:0072201 | 7 | 1 | 18204 | 50 |
NFIB |
1.907e-02 | -3.96 | negative regulation of relaxation of muscle | biological process | GO:1901078 | 7 | 1 | 18204 | 50 |
PDE4B |
1.907e-02 | -3.96 | observational learning | biological process | GO:0098597 | 7 | 1 | 18204 | 50 |
CNTNAP2 |
1.907e-02 | -3.96 | axon choice point recognition | biological process | GO:0016198 | 7 | 1 | 18204 | 50 |
GAP43 |
1.907e-02 | -3.96 | positive regulation of gap junction assembly | biological process | GO:1903598 | 7 | 1 | 18204 | 50 |
CNTNAP2 |
1.907e-02 | -3.96 | central nervous system maturation | biological process | GO:0021626 | 7 | 1 | 18204 | 50 |
CEND1 |
1.907e-02 | -3.96 | glial cell fate specification | biological process | GO:0021780 | 7 | 1 | 18204 | 50 |
NFIB |
1.907e-02 | -3.96 | anterior commissure morphogenesis | biological process | GO:0021960 | 7 | 1 | 18204 | 50 |
NFIB |
1.923e-02 | -3.95 | ESYT1 (extended synaptotagmin 1) | protein interactions | 23344 | 408 | 4 | 19454 | 49 |
RTN1,SNCA,DYNC1LI1,DUSP23 |
1.923e-02 | -3.95 | OCIAD1 (OCIA domain containing 1) | protein interactions | 54940 | 408 | 4 | 19454 | 49 |
MGST3,COX6A1,DYNC1LI1,CLU |
1.943e-02 | -3.94 | COA3 (cytochrome c oxidase assembly factor 3) | protein interactions | 28958 | 85 | 2 | 19454 | 49 |
MGST3,COX5B |
1.943e-02 | -3.94 | DUSP21 (dual specificity phosphatase 21) | protein interactions | 63904 | 85 | 2 | 19454 | 49 |
DUSP23,TAGLN2 |
1.962e-02 | -3.93 | enzyme inhibitor activity | molecular function | GO:0004857 | 390 | 4 | 18094 | 48 |
SPINT2,SCG5,SNCA,OAZ1 |
1.984e-02 | -3.92 | clathrin-coated vesicle | cellular component | GO:0030136 | 220 | 3 | 19108 | 50 |
ATP6V0B,SYT1,CD9 |
1.986e-02 | -3.92 | DHRS4 (dehydrogenase/reductase 4) | protein interactions | 10901 | 86 | 2 | 19454 | 49 |
COX6A1,NDUFA5 |
1.998e-02 | -3.91 | Ywhae (tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide) | protein interactions | 22627 | 8 | 1 | 19454 | 49 |
SNCA |
1.998e-02 | -3.91 | ENPEP (glutamyl aminopeptidase) | protein interactions | 2028 | 8 | 1 | 19454 | 49 |
CCK |
1.998e-02 | -3.91 | Ap2b1 (adaptor-related protein complex 2, beta 1 subunit) | protein interactions | 71770 | 8 | 1 | 19454 | 49 |
SNCA |
1.998e-02 | -3.91 | LAYN (layilin) | protein interactions | 143903 | 8 | 1 | 19454 | 49 |
IGFBP5 |
1.998e-02 | -3.91 | Hspa5 (heat shock protein 5) | protein interactions | 14828 | 8 | 1 | 19454 | 49 |
SNCA |
1.998e-02 | -3.91 | TAFA1 (TAFA chemokine like family member 1) | protein interactions | 407738 | 8 | 1 | 19454 | 49 |
SEZ6L2 |
1.998e-02 | -3.91 | COX7A1 (cytochrome c oxidase subunit 7A1) | protein interactions | 1346 | 8 | 1 | 19454 | 49 |
COX5B |
1.998e-02 | -3.91 | CALML6 (calmodulin like 6) | protein interactions | 163688 | 8 | 1 | 19454 | 49 |
PCP4 |
1.998e-02 | -3.91 | CDR1 (cerebellar degeneration related 1) | protein interactions | 1038 | 8 | 1 | 19454 | 49 |
NDRG4 |
1.998e-02 | -3.91 | PCDHA6 (protocadherin alpha 6) | protein interactions | 56142 | 8 | 1 | 19454 | 49 |
RELN |
1.998e-02 | -3.91 | Vamp2 (vesicle-associated membrane protein 2) | protein interactions | 22318 | 8 | 1 | 19454 | 49 |
SNCA |
1.998e-02 | -3.91 | Chmp2a (charged multivesicular body protein 2A) | protein interactions | 68953 | 8 | 1 | 19454 | 49 |
CLU |
1.998e-02 | -3.91 | COL25A1 (collagen type XXV alpha 1 chain) | protein interactions | 84570 | 8 | 1 | 19454 | 49 |
SNCA |
1.998e-02 | -3.91 | TMEM196 (transmembrane protein 196) | protein interactions | 256130 | 8 | 1 | 19454 | 49 |
PCP4 |
1.998e-02 | -3.91 | Melk (maternal embryonic leucine zipper kinase) | protein interactions | 17279 | 8 | 1 | 19454 | 49 |
TXN |
2.016e-02 | -3.90 | GOLT1B (golgi transport 1B) | protein interactions | 51026 | 230 | 3 | 19454 | 49 |
NDUFA5,ETFB,MGST3 |
2.016e-02 | -3.90 | FFAR1 (free fatty acid receptor 1) | protein interactions | 2864 | 230 | 3 | 19454 | 49 |
COX5B,MGST3,COX6A1 |
2.017e-02 | -3.90 | SOD1 (superoxide dismutase 1) | protein interactions | 6647 | 414 | 4 | 19454 | 49 |
ETFB,TXN,TAGLN2,SNCA |
2.029e-02 | -3.90 | ENO3 (enolase 3) | protein interactions | 2027 | 87 | 2 | 19454 | 49 |
TXN,TAGLN2 |
2.029e-02 | -3.90 | DCTN5 (dynactin subunit 5) | protein interactions | 84516 | 87 | 2 | 19454 | 49 |
TXN,DYNC1LI1 |
2.032e-02 | -3.90 | synaptic vesicle | cellular component | GO:0008021 | 222 | 3 | 19108 | 50 |
PDE4B,SYT1,SNCA |
2.039e-02 | -3.89 | EPB41L3 (erythrocyte membrane protein band 4.1 like 3) | protein interactions | 23136 | 231 | 3 | 19454 | 49 |
SNCA,SCOC,CNTNAP2 |
2.073e-02 | -3.88 | CISD3 (CDGSH iron sulfur domain 3) | protein interactions | 284106 | 88 | 2 | 19454 | 49 |
COX6A1,NDUFA5 |
2.075e-02 | -3.88 | growth cone membrane | cellular component | GO:0032584 | 8 | 1 | 19108 | 50 |
GAP43 |
2.075e-02 | -3.88 | clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane | cellular component | GO:0061202 | 8 | 1 | 19108 | 50 |
SYT1 |
2.075e-02 | -3.88 | clathrin-sculpted gamma-aminobutyric acid transport vesicle | cellular component | GO:0061200 | 8 | 1 | 19108 | 50 |
SYT1 |
2.075e-02 | -3.88 | paranodal junction | cellular component | GO:0033010 | 8 | 1 | 19108 | 50 |
CNTNAP2 |
2.075e-02 | -3.88 | growth factor complex | cellular component | GO:0036454 | 8 | 1 | 19108 | 50 |
IGFBP5 |
2.075e-02 | -3.88 | spherical high-density lipoprotein particle | cellular component | GO:0034366 | 8 | 1 | 19108 | 50 |
CLU |
2.082e-02 | -3.87 | - | gene3d domains | 3.30.460.90 | 8 | 1 | 14470 | 38 |
MAB21L1 |
2.087e-02 | -3.87 | adult locomotory behavior | biological process | GO:0008344 | 81 | 2 | 18204 | 50 |
CEND1,SNCA |
2.087e-02 | -3.87 | diencephalon development | biological process | GO:0021536 | 81 | 2 | 18204 | 50 |
CNTNAP2,NHLH2 |
2.097e-02 | -3.86 | Carboxylesterase_B_AS | interpro domains | IPR019826 | 8 | 1 | 18521 | 49 |
ACHE |
2.103e-02 | -3.86 | lysophosphatidic acid binding | molecular function | GO:0035727 | 8 | 1 | 18094 | 48 |
GAP43 |
2.103e-02 | -3.86 | insulin-like growth factor II binding | molecular function | GO:0031995 | 8 | 1 | 18094 | 48 |
IGFBP5 |
2.103e-02 | -3.86 | oxidoreductase activity, acting on diphenols and related substances as donors | molecular function | GO:0016679 | 8 | 1 | 18094 | 48 |
UQCR10 |
2.106e-02 | -3.86 | glutathione-mediated detoxification | BIOCYC pathways | HUMAN_PWY-4061 | 19 | 1 | 902 | 1 |
MGST3 |
2.117e-02 | -3.85 | secretory vesicle | cellular component | GO:0099503 | 1076 | 7 | 19108 | 50 |
SNCA,SYT1,CD9,SCG5,DYNC1LI1,CLU,PDE4B |
2.117e-02 | -3.85 | GPX4 (glutathione peroxidase 4) | protein interactions | 2879 | 89 | 2 | 19454 | 49 |
ETFB,TAGLN2 |
2.117e-02 | -3.85 | ARL8A (ADP ribosylation factor like GTPase 8A) | protein interactions | 127829 | 89 | 2 | 19454 | 49 |
RUFY3,TAGLN2 |
2.117e-02 | -3.85 | SERPINB13 (serpin family B member 13) | protein interactions | 5275 | 89 | 2 | 19454 | 49 |
PCP4,SNCA |
2.130e-02 | -3.85 | KLF16 (KLF transcription factor 16) | protein interactions | 83855 | 421 | 4 | 19454 | 49 |
NFIB,COX5B,NDUFA5,COX6A1 |
2.135e-02 | -3.85 | regulation of neurotransmitter secretion | biological process | GO:0046928 | 82 | 2 | 18204 | 50 |
SYT1,SNCA |
2.139e-02 | -3.84 | antioxidant activity | molecular function | GO:0016209 | 85 | 2 | 18094 | 48 |
TXN,MGST3 |
2.140e-02 | -3.84 | positive regulation of cellular process | biological process | GO:0048522 | 5719 | 23 | 18204 | 50 |
DYNC1LI1,CLU,C1QTNF3,PCP4,CHD5,MLLT11,OAZ1,TSTD1,SNCA,IGFBP5,TXN,SYT1,RUFY3,RELN,NDRG4,PDE4B,CNTNAP2,OLFM1,NFIB,NHLH2,SCOC,MAB21L1,ACHE |
2.146e-02 | -3.84 | purine nucleotide biosynthetic process | biological process | GO:0006164 | 216 | 3 | 18204 | 50 |
NDUFB2,NDUFA5,NDUFA1 |
2.147e-02 | -3.84 | CARBOXYLESTERASE_B_1 | prosite domains | PS00122 | 8 | 1 | 12186 | 33 |
ACHE |
2.162e-02 | -3.83 | TXNDC11 (thioredoxin domain containing 11) | protein interactions | 51061 | 90 | 2 | 19454 | 49 |
CLU,OLFM1 |
2.162e-02 | -3.83 | TMEM60 (transmembrane protein 60) | protein interactions | 85025 | 90 | 2 | 19454 | 49 |
MGST3,SYT1 |
2.177e-02 | -3.83 | myotube differentiation involved in skeletal muscle regeneration | biological process | GO:0014908 | 8 | 1 | 18204 | 50 |
CD9 |
2.177e-02 | -3.83 | regulation of synaptic transmission, cholinergic | biological process | GO:0032222 | 8 | 1 | 18204 | 50 |
ACHE |
2.177e-02 | -3.83 | regulation of chaperone-mediated autophagy | biological process | GO:1904714 | 8 | 1 | 18204 | 50 |
SNCA |
2.177e-02 | -3.83 | reelin-mediated signaling pathway | biological process | GO:0038026 | 8 | 1 | 18204 | 50 |
RELN |
2.177e-02 | -3.83 | mammary gland involution | biological process | GO:0060056 | 8 | 1 | 18204 | 50 |
IGFBP5 |
2.177e-02 | -3.83 | hypothalamus gonadotrophin-releasing hormone neuron development | biological process | GO:0021888 | 8 | 1 | 18204 | 50 |
NHLH2 |
2.177e-02 | -3.83 | protein import | biological process | GO:0017038 | 8 | 1 | 18204 | 50 |
CLU |
2.177e-02 | -3.83 | regulation of dopamine uptake involved in synaptic transmission | biological process | GO:0051584 | 8 | 1 | 18204 | 50 |
SNCA |
2.177e-02 | -3.83 | negative regulation of oxidative phosphorylation | biological process | GO:0090324 | 8 | 1 | 18204 | 50 |
SNCA |
2.177e-02 | -3.83 | intracellular triglyceride homeostasis | biological process | GO:0035356 | 8 | 1 | 18204 | 50 |
C1QTNF3 |
2.177e-02 | -3.83 | type I pneumocyte differentiation | biological process | GO:0060509 | 8 | 1 | 18204 | 50 |
NFIB |
2.177e-02 | -3.83 | atrioventricular valve formation | biological process | GO:0003190 | 8 | 1 | 18204 | 50 |
OLFM1 |
2.177e-02 | -3.83 | hypothalamus gonadotrophin-releasing hormone neuron differentiation | biological process | GO:0021886 | 8 | 1 | 18204 | 50 |
NHLH2 |
2.177e-02 | -3.83 | regulation of catecholamine uptake involved in synaptic transmission | biological process | GO:0051940 | 8 | 1 | 18204 | 50 |
SNCA |
2.184e-02 | -3.82 | regulation of amine transport | biological process | GO:0051952 | 83 | 2 | 18204 | 50 |
SNCA,SYT1 |
2.224e-02 | -3.81 | regulation of synaptic plasticity | biological process | GO:0048167 | 219 | 3 | 18204 | 50 |
CALB2,SNCA,RELN |
2.230e-02 | -3.80 | ORF8 (ORF8 protein) | protein interactions | 43740577 | 427 | 4 | 19454 | 49 |
ETFB,SH3BGRL3,MGST3,CLU |
2.233e-02 | -3.80 | membrane docking | biological process | GO:0022406 | 84 | 2 | 18204 | 50 |
SYT1,NDRG4 |
2.245e-02 | -3.80 | HSP104 (chaperone ATPase HSP104) | protein interactions | 850633 | 9 | 1 | 19454 | 49 |
SNCA |
2.245e-02 | -3.80 | SLC25A26 (solute carrier family 25 member 26) | protein interactions | 115286 | 9 | 1 | 19454 | 49 |
DUSP23 |
2.245e-02 | -3.80 | Hspa9 (heat shock protein 9) | protein interactions | 15526 | 9 | 1 | 19454 | 49 |
SNCA |
2.245e-02 | -3.80 | ADAM2 (ADAM metallopeptidase domain 2) | protein interactions | 2515 | 9 | 1 | 19454 | 49 |
CD9 |
2.245e-02 | -3.80 | Ywhag (tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide) | protein interactions | 22628 | 9 | 1 | 19454 | 49 |
SNCA |
2.253e-02 | -3.79 | RIC8A (RIC8 guanine nucleotide exchange factor A) | protein interactions | 60626 | 92 | 2 | 19454 | 49 |
PDE4B,SNCA |
2.253e-02 | -3.79 | NDUFB11 (NADH:ubiquinone oxidoreductase subunit B11) | protein interactions | 54539 | 92 | 2 | 19454 | 49 |
NDUFA1,NDUFA5 |
2.253e-02 | -3.79 | IST1 (IST1 factor associated with ESCRT-III) | protein interactions | 9798 | 92 | 2 | 19454 | 49 |
SNCA,ISOC1 |
2.253e-02 | -3.79 | EDRF1 (erythroid differentiation regulatory factor 1) | protein interactions | 26098 | 92 | 2 | 19454 | 49 |
DUSP23,MAB21L1 |
2.258e-02 | -3.79 | ribonucleotide metabolic process | biological process | GO:0009259 | 393 | 4 | 18204 | 50 |
NDUFB2,PDE4B,NDUFA1,NDUFA5 |
2.272e-02 | -3.78 | human chr5q23.3 | chromosome location | human chr5q23.3 | 12 | 1 | 26134 | 50 |
ISOC1 |
2.277e-02 | -3.78 | DYNLT1 (dynein light chain Tctex-type 1) | protein interactions | 6993 | 241 | 3 | 19454 | 49 |
DYNC1LI1,TXN,ETFB |
2.277e-02 | -3.78 | positive regulation of DNA-binding transcription factor activity | biological process | GO:0051091 | 221 | 3 | 18204 | 50 |
NHLH2,CLU,RELN |
2.299e-02 | -3.77 | LCP1 (lymphocyte cytosolic protein 1) | protein interactions | 3936 | 93 | 2 | 19454 | 49 |
PDE4B,DYNC1LI1 |
2.302e-02 | -3.77 | PAFAH1B1 (platelet activating factor acetylhydrolase 1b regulatory subunit 1) | protein interactions | 5048 | 242 | 3 | 19454 | 49 |
PDE4B,DYNC1LI1,ISOC1 |
2.320e-02 | -3.76 | Myometrial Relaxation and Contraction Pathways | WikiPathways | WP289 | 158 | 3 | 5310 | 21 |
PDE4B,IGFBP5,GNG3 |
2.326e-02 | -3.76 | NDUFS8 (NADH:ubiquinone oxidoreductase core subunit S8) | protein interactions | 4728 | 243 | 3 | 19454 | 49 |
NDUFA5,SNCA,NDUFA1 |
2.331e-02 | -3.76 | amyloid-beta binding | molecular function | GO:0001540 | 89 | 2 | 18094 | 48 |
CLU,ACHE |
2.331e-02 | -3.76 | chromaffin granule membrane | cellular component | GO:0042584 | 9 | 1 | 19108 | 50 |
SYT1 |
2.334e-02 | -3.76 | central nervous system neuron development | biological process | GO:0021954 | 86 | 2 | 18204 | 50 |
NHLH2,NFIB |
2.342e-02 | -3.75 | EGF-like_dom | interpro domains | IPR000742 | 232 | 3 | 18521 | 49 |
RELN,CNTNAP2,DNER |
2.345e-02 | -3.75 | TTR (transthyretin) | protein interactions | 7276 | 94 | 2 | 19454 | 49 |
CLU,NDUFA5 |
2.345e-02 | -3.75 | NDUFB3 (NADH:ubiquinone oxidoreductase subunit B3) | protein interactions | 4709 | 94 | 2 | 19454 | 49 |
NDUFA1,NDUFA5 |
2.345e-02 | -3.75 | AAR2 (AAR2 splicing factor) | protein interactions | 25980 | 651 | 5 | 19454 | 49 |
ISOC1,TAGLN2,DUSP23,TXN,MGST3 |
2.357e-02 | -3.75 | Quino_amine_DH_bsu | interpro domains | IPR011044 | 9 | 1 | 18521 | 49 |
OLFM1 |
2.358e-02 | -3.75 | axon guidance | biological process | GO:0007411 | 224 | 3 | 18204 | 50 |
RELN,GAP43,NFIB |
2.358e-02 | -3.75 | purine-containing compound biosynthetic process | biological process | GO:0072522 | 224 | 3 | 18204 | 50 |
NDUFB2,NDUFA1,NDUFA5 |
2.358e-02 | -3.75 | neuron projection guidance | biological process | GO:0097485 | 224 | 3 | 18204 | 50 |
RELN,GAP43,NFIB |
2.363e-02 | -3.75 | cuprous ion binding | molecular function | GO:1903136 | 9 | 1 | 18094 | 48 |
SNCA |
2.363e-02 | -3.75 | protein-disulfide reductase (NAD(P)H) activity | molecular function | GO:0047134 | 9 | 1 | 18094 | 48 |
TXN |
2.374e-02 | -3.74 | Morphine addiction | KEGG pathways | ko05032 | 91 | 2 | 7161 | 19 |
PDE4B,GNG3 |
2.374e-02 | -3.74 | Morphine addiction | KEGG pathways | hsa05032 | 91 | 2 | 7161 | 19 |
GNG3,PDE4B |
2.384e-02 | -3.74 | associative learning | biological process | GO:0008306 | 87 | 2 | 18204 | 50 |
NDRG4,RELN |
2.385e-02 | -3.74 | striated muscle cell differentiation | biological process | GO:0051146 | 225 | 3 | 18204 | 50 |
CD9,IGFBP5,DNER |
2.391e-02 | -3.73 | NME3 (NME/NM23 nucleoside diphosphate kinase 3) | protein interactions | 4832 | 95 | 2 | 19454 | 49 |
DUSP23,MGST3 |
2.410e-02 | -3.73 | regulation of cell growth | biological process | GO:0001558 | 401 | 4 | 18204 | 50 |
OLFM1,SYT1,RUFY3,IGFBP5 |
2.436e-02 | -3.71 | neurotransmitter secretion | biological process | GO:0007269 | 88 | 2 | 18204 | 50 |
SYT1,SNCA |
2.436e-02 | -3.71 | positive regulation of peptidyl-serine phosphorylation | biological process | GO:0033138 | 88 | 2 | 18204 | 50 |
TXN,SNCA |
2.436e-02 | -3.71 | signal release from synapse | biological process | GO:0099643 | 88 | 2 | 18204 | 50 |
SYT1,SNCA |
2.438e-02 | -3.71 | NDUFB7 (NADH:ubiquinone oxidoreductase subunit B7) | protein interactions | 4713 | 96 | 2 | 19454 | 49 |
NDUFB2,NDUFA1 |
2.439e-02 | -3.71 | regulation of growth | biological process | GO:0040008 | 603 | 5 | 18204 | 50 |
SYT1,RUFY3,OLFM1,GAP43,IGFBP5 |
2.446e-02 | -3.71 | positive regulation of mitochondrial depolarization | biological process | GO:0051901 | 9 | 1 | 18204 | 50 |
MLLT11 |
2.446e-02 | -3.71 | calmodulin dependent kinase signaling pathway | biological process | GO:0099004 | 9 | 1 | 18204 | 50 |
PCP4 |
2.446e-02 | -3.71 | cAMP catabolic process | biological process | GO:0006198 | 9 | 1 | 18204 | 50 |
PDE4B |
2.446e-02 | -3.71 | regulation of cerebellar granule cell precursor proliferation | biological process | GO:0021936 | 9 | 1 | 18204 | 50 |
CEND1 |
2.446e-02 | -3.71 | microglial cell proliferation | biological process | GO:0061518 | 9 | 1 | 18204 | 50 |
CLU |
2.446e-02 | -3.71 | protein localization to axon | biological process | GO:0099612 | 9 | 1 | 18204 | 50 |
CNTNAP2 |
2.446e-02 | -3.71 | positive regulation of synapse maturation | biological process | GO:0090129 | 9 | 1 | 18204 | 50 |
RELN |
2.446e-02 | -3.71 | Notch receptor processing | biological process | GO:0007220 | 9 | 1 | 18204 | 50 |
DNER |
2.446e-02 | -3.71 | dopamine biosynthetic process | biological process | GO:0042416 | 9 | 1 | 18204 | 50 |
SNCA |
2.446e-02 | -3.71 | spontaneous synaptic transmission | biological process | GO:0098814 | 9 | 1 | 18204 | 50 |
SYT1 |
2.446e-02 | -3.71 | negative regulation of insulin-like growth factor receptor signaling pathway | biological process | GO:0043569 | 9 | 1 | 18204 | 50 |
IGFBP5 |
2.446e-02 | -3.71 | negative regulation of neurotransmitter transport | biological process | GO:0051589 | 9 | 1 | 18204 | 50 |
SNCA |
2.446e-02 | -3.71 | hindbrain radial glia guided cell migration | biological process | GO:0021932 | 9 | 1 | 18204 | 50 |
CEND1 |
2.446e-02 | -3.71 | macrophage proliferation | biological process | GO:0061517 | 9 | 1 | 18204 | 50 |
CLU |
2.446e-02 | -3.71 | negative regulation of cellular respiration | biological process | GO:1901856 | 9 | 1 | 18204 | 50 |
SNCA |
2.452e-02 | -3.71 | EF-hand_6 | pfam domains | PF13405 | 9 | 1 | 17795 | 49 |
CALB2 |
2.468e-02 | -3.70 | clathrin-coated endocytic vesicle | cellular component | GO:0045334 | 93 | 2 | 19108 | 50 |
SYT1,CD9 |
2.470e-02 | -3.70 | regulation of secretion | biological process | GO:0051046 | 605 | 5 | 18204 | 50 |
SNCA,C1QTNF3,SCG5,SYT1,ACHE |
2.474e-02 | -3.70 | Transmission across Chemical Synapses | REACTOME pathways | R-HSA-112315 | 217 | 3 | 10285 | 30 |
SYT1,ACHE,GNG3 |
2.478e-02 | -3.70 | UBQLN4 (ubiquilin 4) | protein interactions | 56893 | 249 | 3 | 19454 | 49 |
TXN,CEND1,SCG5 |
2.478e-02 | -3.70 | TPR (translocated promoter region, nuclear basket protein) | protein interactions | 7175 | 249 | 3 | 19454 | 49 |
TXN,SNCA,DYNC1LI1 |
2.486e-02 | -3.69 | TYMS (thymidylate synthetase) | protein interactions | 7298 | 97 | 2 | 19454 | 49 |
RTN1,TXN |
2.486e-02 | -3.69 | GSTO1 (glutathione S-transferase omega 1) | protein interactions | 9446 | 97 | 2 | 19454 | 49 |
TXN,TAGLN2 |
2.486e-02 | -3.69 | STXBP3 (syntaxin binding protein 3) | protein interactions | 6814 | 97 | 2 | 19454 | 49 |
SH3BGRL3,SNCA |
2.487e-02 | -3.69 | biogenic amine metabolic process | biological process | GO:0006576 | 89 | 2 | 18204 | 50 |
SNCA,OAZ1 |
2.491e-02 | -3.69 | COX7B2 (cytochrome c oxidase subunit 7B2) | protein interactions | 170712 | 10 | 1 | 19454 | 49 |
COX5B |
2.491e-02 | -3.69 | Ywhaz (tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide) | protein interactions | 22631 | 10 | 1 | 19454 | 49 |
SNCA |
2.491e-02 | -3.69 | Cltc (clathrin heavy chain) | protein interactions | 67300 | 10 | 1 | 19454 | 49 |
SNCA |
2.491e-02 | -3.69 | IAPP (islet amyloid polypeptide) | protein interactions | 3375 | 10 | 1 | 19454 | 49 |
SNCA |
2.491e-02 | -3.69 | HGSNAT (heparan-alpha-glucosaminide N-acetyltransferase) | protein interactions | 138050 | 10 | 1 | 19454 | 49 |
NRN1 |
2.491e-02 | -3.69 | CLDN20 (claudin 20) | protein interactions | 49861 | 10 | 1 | 19454 | 49 |
IGFBP5 |
2.491e-02 | -3.69 | SVOPL (SVOP like) | protein interactions | 136306 | 10 | 1 | 19454 | 49 |
PCP4 |
2.491e-02 | -3.69 | ACHE (acetylcholinesterase (Yt blood group)) | protein interactions | 43 | 10 | 1 | 19454 | 49 |
ACHE |
2.514e-02 | -3.68 | exocytic vesicle | cellular component | GO:0070382 | 241 | 3 | 19108 | 50 |
SYT1,SNCA,PDE4B |
2.528e-02 | -3.68 | Opioid Signalling | REACTOME pathways | R-HSA-111885 | 85 | 2 | 10285 | 30 |
PDE4B,GNG3 |
2.528e-02 | -3.68 | ribose phosphate metabolic process | biological process | GO:0019693 | 407 | 4 | 18204 | 50 |
NDUFA5,NDUFA1,NDUFB2,PDE4B |
2.534e-02 | -3.68 | CD53 (CD53 molecule) | protein interactions | 963 | 98 | 2 | 19454 | 49 |
IGFBP5,CD9 |
2.534e-02 | -3.68 | FAM210B (family with sequence similarity 210 member B) | protein interactions | 116151 | 98 | 2 | 19454 | 49 |
ATP6V0B,RTN1 |
2.534e-02 | -3.68 | MTFMT (mitochondrial methionyl-tRNA formyltransferase) | protein interactions | 123263 | 98 | 2 | 19454 | 49 |
NDUFA5,ETFB |
2.534e-02 | -3.68 | GNAO1 (G protein subunit alpha o1) | protein interactions | 2775 | 98 | 2 | 19454 | 49 |
SNCA,GNG3 |
2.548e-02 | -3.67 | DPP4 (dipeptidyl peptidase 4) | protein interactions | 1803 | 445 | 4 | 19454 | 49 |
NDUFA5,COX5B,SPINT2,CLU |
2.587e-02 | -3.65 | vacuolar proton-transporting V-type ATPase, V0 domain | cellular component | GO:0000220 | 10 | 1 | 19108 | 50 |
ATP6V0B |
2.592e-02 | -3.65 | cellular oxidant detoxification | biological process | GO:0098869 | 91 | 2 | 18204 | 50 |
MGST3,TXN |
2.592e-02 | -3.65 | regulation of smooth muscle cell migration | biological process | GO:0014910 | 91 | 2 | 18204 | 50 |
IGFBP5,NDRG4 |
2.596e-02 | -3.65 | Terminal pathway of complement | REACTOME pathways | R-HSA-166665 | 9 | 1 | 10285 | 30 |
CLU |
2.609e-02 | -3.65 | Mitochondrial Electron Transport Chain | SMPDB pathways | SMP0000355 | 12 | 1 | 1369 | 3 |
NDUFA1 |
2.622e-02 | -3.64 | acetylcholine binding | molecular function | GO:0042166 | 10 | 1 | 18094 | 48 |
ACHE |
2.623e-02 | -3.64 | Cytochrome bc1 complex | KEGG pathways | hsa_M00152 | 10 | 1 | 7161 | 19 |
UQCR10 |
2.623e-02 | -3.64 | Cytochrome bc1 complex | KEGG pathways | M00152 | 10 | 1 | 7161 | 19 |
UQCR10 |
2.630e-02 | -3.64 | ANXA6 (annexin A6) | protein interactions | 309 | 100 | 2 | 19454 | 49 |
PDE4B,SNCA |
2.630e-02 | -3.64 | EDEM2 (ER degradation enhancing alpha-mannosidase like protein 2) | protein interactions | 55741 | 100 | 2 | 19454 | 49 |
CLU,OLFM1 |
2.636e-02 | -3.64 | postsynapse | cellular component | GO:0098794 | 646 | 5 | 19108 | 50 |
GAP43,GNG3,RTN1,PDE4B,SNCA |
2.661e-02 | -3.63 | PEBP1 (phosphatidylethanolamine binding protein 1) | protein interactions | 5037 | 256 | 3 | 19454 | 49 |
SNCA,MLLT11,SH3BGRL3 |
2.668e-02 | -3.62 | organelle | cellular component | GO:0043226 | 14500 | 44 | 19108 | 50 |
CHD5,TSTD1,NDRG4,SCOC,DYNC1LI1,SNCA,C1QTNF3,CD9,COX6A1,MLLT11,MAB21L1,ATP6V0B,GNG3,NDUFB2,IGFBP5,CEND1,SH3BGRL3,CNTNAP2,UQCR10,OAZ1,TAGLN2,NFIB,CLU,ACHE,SYT1,EMX2,CALB2,MGST3,SCG5,NDUFA1,PDE4B,DUSP23,DNER,PCP4,SEZ6L2,NHLH2,NDUFA5,TXN,OLFM1,ETFB,COX5B,GAP43,ISOC1,RTN1 |
2.674e-02 | -3.62 | Galactose-binding domain-like | gene3d domains | 2.60.120.260 | 97 | 2 | 14470 | 38 |
CNTNAP2,RELN |
2.676e-02 | -3.62 | GLUTAREDOXIN_2 | prosite domains | PS51354 | 10 | 1 | 12186 | 33 |
SH3BGRL3 |
2.679e-02 | -3.62 | RAB5IF (RAB5 interacting factor) | protein interactions | 55969 | 101 | 2 | 19454 | 49 |
MGST3,SPINT2 |
2.679e-02 | -3.62 | CGRRF1 (cell growth regulator with ring finger domain 1) | protein interactions | 10668 | 101 | 2 | 19454 | 49 |
SNCA,MGST3 |
2.679e-02 | -3.62 | RRAS2 (RAS related 2) | protein interactions | 22800 | 101 | 2 | 19454 | 49 |
DUSP23,SNCA |
2.679e-02 | -3.62 | AGTR1 (angiotensin II receptor type 1) | protein interactions | 185 | 101 | 2 | 19454 | 49 |
SCG5,OAZ1 |
2.699e-02 | -3.61 | positive regulation of intracellular protein transport | biological process | GO:0090316 | 93 | 2 | 18204 | 50 |
OAZ1,RUFY3 |
2.699e-02 | -3.61 | regulation of extent of cell growth | biological process | GO:0061387 | 93 | 2 | 18204 | 50 |
RUFY3,OLFM1 |
2.714e-02 | -3.61 | Golgi lumen acidification | biological process | GO:0061795 | 10 | 1 | 18204 | 50 |
ATP6V0B |
2.714e-02 | -3.61 | learned vocalization behavior or vocal learning | biological process | GO:0098598 | 10 | 1 | 18204 | 50 |
CNTNAP2 |
2.714e-02 | -3.61 | lung secretory cell differentiation | biological process | GO:0061140 | 10 | 1 | 18204 | 50 |
NFIB |
2.714e-02 | -3.61 | regulation of gap junction assembly | biological process | GO:1903596 | 10 | 1 | 18204 | 50 |
CNTNAP2 |
2.737e-02 | -3.60 | SV2C (synaptic vesicle glycoprotein 2C) | protein interactions | 22987 | 11 | 1 | 19454 | 49 |
SYT1 |
2.737e-02 | -3.60 | RSP5 (NEDD4 family E3 ubiquitin-protein ligase) | protein interactions | 856862 | 11 | 1 | 19454 | 49 |
SNCA |
2.737e-02 | -3.60 | Caskin1 (CASK interacting protein 1) | protein interactions | 140722 | 11 | 1 | 19454 | 49 |
SYT1 |
2.737e-02 | -3.60 | CD38 (CD38 molecule) | protein interactions | 952 | 11 | 1 | 19454 | 49 |
CD9 |
2.737e-02 | -3.60 | PDE7B (phosphodiesterase 7B) | protein interactions | 27115 | 11 | 1 | 19454 | 49 |
RUFY3 |
2.737e-02 | -3.60 | MSRB1 (methionine sulfoxide reductase B1) | protein interactions | 51734 | 11 | 1 | 19454 | 49 |
CLU |
2.737e-02 | -3.60 | IDO2 (indoleamine 2,3-dioxygenase 2) | protein interactions | 169355 | 11 | 1 | 19454 | 49 |
NRN1 |
2.737e-02 | -3.60 | PM20D1 (peptidase M20 domain containing 1) | protein interactions | 148811 | 11 | 1 | 19454 | 49 |
PCP4 |
2.737e-02 | -3.60 | MS4A7 (membrane spanning 4-domains A7) | protein interactions | 58475 | 11 | 1 | 19454 | 49 |
IGFBP5 |
2.737e-02 | -3.60 | Selenium Micronutrient Network | WikiPathways | WP1310 | 7 | 1 | 5310 | 21 |
TXN |
2.737e-02 | -3.60 | Selenium Micronutrient Network | WikiPathways | WP1272 | 7 | 1 | 5310 | 21 |
TXN |
2.737e-02 | -3.60 | Gastric acid production | WikiPathways | WP2596 | 7 | 1 | 5310 | 21 |
CCK |
2.737e-02 | -3.60 | Acetylcholine Synthesis | WikiPathways | WP528 | 7 | 1 | 5310 | 21 |
ACHE |
2.778e-02 | -3.58 | CD63 (CD63 molecule) | protein interactions | 967 | 103 | 2 | 19454 | 49 |
CD9,SYT1 |
2.778e-02 | -3.58 | OTC (ornithine transcarbamylase) | protein interactions | 5009 | 103 | 2 | 19454 | 49 |
NDUFA5,ETFB |
2.781e-02 | -3.58 | endomembrane system | cellular component | GO:0012505 | 4764 | 19 | 19108 | 50 |
IGFBP5,SEZ6L2,CNTNAP2,CLU,SYT1,OLFM1,ACHE,MGST3,SCG5,RTN1,RUFY3,SCOC,NDRG4,PDE4B,DYNC1LI1,SNCA,CD9,ATP6V0B,DNER |
2.795e-02 | -3.58 | axon development | biological process | GO:0061564 | 420 | 4 | 18204 | 50 |
NFIB,CCK,GAP43,RELN |
2.807e-02 | -3.57 | hippocampus development | biological process | GO:0021766 | 95 | 2 | 18204 | 50 |
RELN,EMX2 |
2.828e-02 | -3.57 | TBCB (tubulin folding cofactor B) | protein interactions | 1155 | 104 | 2 | 19454 | 49 |
ISOC1,SNCA |
2.832e-02 | -3.56 | human chr12q21.2 | chromosome location | human chr12q21.2 | 15 | 1 | 26134 | 50 |
SYT1 |
2.832e-02 | -3.56 | human chr4q31.1 | chromosome location | human chr4q31.1 | 15 | 1 | 26134 | 50 |
SCOC |
2.873e-02 | -3.55 | Insulin_GF-bd_Cys-rich_CS | interpro domains | IPR017891 | 11 | 1 | 18521 | 49 |
IGFBP5 |
2.873e-02 | -3.55 | Mab-21_HhH/H2TH-like | interpro domains | IPR046906 | 11 | 1 | 18521 | 49 |
MAB21L1 |
2.873e-02 | -3.55 | SM22_calponin | interpro domains | IPR003096 | 11 | 1 | 18521 | 49 |
TAGLN2 |
2.880e-02 | -3.55 | Neurotransmitter Clearance In The Synaptic Cleft | REACTOME pathways | R-HSA-112311 | 10 | 1 | 10285 | 30 |
ACHE |
2.880e-02 | -3.55 | Neurotoxicity of clostridium toxins | REACTOME pathways | R-HSA-168799 | 10 | 1 | 10285 | 30 |
SYT1 |
2.880e-02 | -3.55 | sulfurtransferase activity | molecular function | GO:0016783 | 11 | 1 | 18094 | 48 |
TSTD1 |
2.881e-02 | -3.55 | growth | biological process | GO:0040007 | 424 | 4 | 18204 | 50 |
NRN1,NDRG4,GAP43,CD9 |
2.881e-02 | -3.55 | developmental growth | biological process | GO:0048589 | 424 | 4 | 18204 | 50 |
CD9,GAP43,NRN1,NDRG4 |
2.883e-02 | -3.55 | secretory granule | cellular component | GO:0030141 | 897 | 6 | 19108 | 50 |
CD9,SYT1,SNCA,CLU,DYNC1LI1,SCG5 |
2.940e-02 | -3.53 | IGFBP_N_1 | prosite domains | PS00222 | 11 | 1 | 12186 | 33 |
IGFBP5 |
2.972e-02 | -3.52 | amine metabolic process | biological process | GO:0009308 | 98 | 2 | 18204 | 50 |
OAZ1,SNCA |
2.980e-02 | -3.51 | VMA21 (vacuolar ATPase assembly factor VMA21) | protein interactions | 203547 | 107 | 2 | 19454 | 49 |
THSD7A,ATP6V0B |
2.981e-02 | -3.51 | catecholamine uptake | biological process | GO:0090493 | 11 | 1 | 18204 | 50 |
SNCA |
2.981e-02 | -3.51 | negative regulation of muscle adaptation | biological process | GO:0014745 | 11 | 1 | 18204 | 50 |
IGFBP5 |
2.981e-02 | -3.51 | regulation of peptidyl-cysteine S-nitrosylation | biological process | GO:2000169 | 11 | 1 | 18204 | 50 |
TXN |
2.981e-02 | -3.51 | dopamine uptake | biological process | GO:0090494 | 11 | 1 | 18204 | 50 |
SNCA |
2.981e-02 | -3.51 | fatty acid beta-oxidation using acyl-CoA dehydrogenase | biological process | GO:0033539 | 11 | 1 | 18204 | 50 |
ETFB |
2.981e-02 | -3.51 | negative regulation of platelet aggregation | biological process | GO:0090331 | 11 | 1 | 18204 | 50 |
CD9 |
2.981e-02 | -3.51 | positive regulation of membrane depolarization | biological process | GO:1904181 | 11 | 1 | 18204 | 50 |
MLLT11 |
2.982e-02 | -3.51 | ADGRG3 (adhesion G protein-coupled receptor G3) | protein interactions | 222487 | 12 | 1 | 19454 | 49 |
ATP6V0B |
2.982e-02 | -3.51 | OAZ2 (ornithine decarboxylase antizyme 2) | protein interactions | 4947 | 12 | 1 | 19454 | 49 |
OAZ1 |
2.982e-02 | -3.51 | OLFML3 (olfactomedin like 3) | protein interactions | 56944 | 12 | 1 | 19454 | 49 |
UQCR10 |
2.982e-02 | -3.51 | ORF17.5 (ORF17.5) | protein interactions | 4961482 | 12 | 1 | 19454 | 49 |
SCOC |
2.982e-02 | -3.51 | MMP25 (matrix metallopeptidase 25) | protein interactions | 64386 | 12 | 1 | 19454 | 49 |
CLU |
2.982e-02 | -3.51 | TREM2 (triggering receptor expressed on myeloid cells 2) | protein interactions | 54209 | 12 | 1 | 19454 | 49 |
CLU |
2.982e-02 | -3.51 | Actr1a (ARP1 actin-related protein 1A, centractin alpha) | protein interactions | 54130 | 12 | 1 | 19454 | 49 |
SNCA |
2.982e-02 | -3.51 | NPEPPSP1 (NPEPPS pseudogene 1) | protein interactions | 440434 | 12 | 1 | 19454 | 49 |
DUSP23 |
2.982e-02 | -3.51 | NCF4 (neutrophil cytosolic factor 4) | protein interactions | 4689 | 12 | 1 | 19454 | 49 |
TXN |
2.982e-02 | -3.51 | NKX2-4 (NK2 homeobox 4) | protein interactions | 644524 | 12 | 1 | 19454 | 49 |
NFIB |
2.982e-02 | -3.51 | Mark2 (MAP/microtubule affinity regulating kinase 2) | protein interactions | 13728 | 12 | 1 | 19454 | 49 |
SNCA |
2.982e-02 | -3.51 | C21orf91 (chromosome 21 open reading frame 91) | protein interactions | 54149 | 12 | 1 | 19454 | 49 |
SCOC |
2.982e-02 | -3.51 | FAM222A (family with sequence similarity 222 member A) | protein interactions | 84915 | 12 | 1 | 19454 | 49 |
MAB21L1 |
2.988e-02 | -3.51 | Mab-21_C | pfam domains | PF20266 | 11 | 1 | 17795 | 49 |
MAB21L1 |
2.998e-02 | -3.51 | HSPD1 (heat shock protein family D (Hsp60) member 1) | protein interactions | 3329 | 941 | 6 | 19454 | 49 |
TXN,COX5B,PDE4B,NDUFA5,ETFB,CLU |
3.000e-02 | -3.51 | modified amino acid binding | molecular function | GO:0072341 | 102 | 2 | 18094 | 48 |
SYT1,GAP43 |
3.016e-02 | -3.50 | SNCA (synuclein alpha) | protein interactions | 6622 | 696 | 5 | 19454 | 49 |
SNCA,RUFY3,DYNC1LI1,TAGLN2,CLU |
3.018e-02 | -3.50 | human chr6p25.1 | chromosome location | human chr6p25.1 | 16 | 1 | 26134 | 50 |
NRN1 |
3.028e-02 | -3.50 | regulation of neurotransmitter transport | biological process | GO:0051588 | 99 | 2 | 18204 | 50 |
SNCA,SYT1 |
3.030e-02 | -3.50 | human chr7q22.1 | chromosome location | human chr7q22.1 | 142 | 2 | 26134 | 50 |
RELN,ACHE |
3.031e-02 | -3.50 | CLASP1 (cytoplasmic linker associated protein 1) | protein interactions | 23332 | 108 | 2 | 19454 | 49 |
SNCA,DYNC1LI1 |
3.031e-02 | -3.50 | FKBP1A (FKBP prolyl isomerase 1A) | protein interactions | 2280 | 108 | 2 | 19454 | 49 |
TXN,TAGLN2 |
3.031e-02 | -3.50 | BIN1 (bridging integrator 1) | protein interactions | 274 | 108 | 2 | 19454 | 49 |
CLU,SNCA |
3.039e-02 | -3.49 | skin-hand-carcinoma-squamous_cell_carcinoma | COSMIC cancer mutations | skin-hand-carcinoma-squamous_cell_carcinoma | 407 | 4 | 16828 | 49 |
RELN,SEZ6L2,DNER,PDE4B |
3.096e-02 | -3.48 | mitochondrial respiratory chain complex III | cellular component | GO:0005750 | 12 | 1 | 19108 | 50 |
UQCR10 |
3.096e-02 | -3.48 | juxtaparanode region of axon | cellular component | GO:0044224 | 12 | 1 | 19108 | 50 |
CNTNAP2 |
3.096e-02 | -3.48 | clathrin-sculpted vesicle | cellular component | GO:0060198 | 12 | 1 | 19108 | 50 |
SYT1 |
3.096e-02 | -3.48 | paranode region of axon | cellular component | GO:0033270 | 12 | 1 | 19108 | 50 |
CNTNAP2 |
3.096e-02 | -3.48 | proton-transporting V-type ATPase, V0 domain | cellular component | GO:0033179 | 12 | 1 | 19108 | 50 |
ATP6V0B |
3.096e-02 | -3.48 | respiratory chain complex III | cellular component | GO:0045275 | 12 | 1 | 19108 | 50 |
UQCR10 |
3.104e-02 | -3.47 | regulation of cellular component organization | biological process | GO:0051128 | 2455 | 12 | 18204 | 50 |
RUFY3,CLU,DYNC1LI1,MLLT11,NDRG4,RELN,CNTNAP2,OLFM1,SYT1,IGFBP5,SNCA,GAP43 |
3.106e-02 | -3.47 | RDX (radixin) | protein interactions | 5962 | 272 | 3 | 19454 | 49 |
RTN1,TAGLN2,SNCA |
3.115e-02 | -3.47 | SM22CALPONIN | prints domains | PR00888 | 11 | 1 | 5227 | 15 |
TAGLN2 |
3.115e-02 | -3.47 | THIOREDOXIN | prints domains | PR00421 | 11 | 1 | 5227 | 15 |
TXN |
3.122e-02 | -3.47 | Glial Cell Differentiation | WikiPathways | WP2276 | 8 | 1 | 5310 | 21 |
GAP43 |
3.130e-02 | -3.46 | MAD_homology1_Dwarfin-type | interpro domains | IPR003619 | 12 | 1 | 18521 | 49 |
NFIB |
3.130e-02 | -3.46 | Mab-21-like | interpro domains | IPR024810 | 12 | 1 | 18521 | 49 |
MAB21L1 |
3.135e-02 | -3.46 | UBIAD1 (UbiA prenyltransferase domain containing 1) | protein interactions | 29914 | 110 | 2 | 19454 | 49 |
MGST3,SYT1 |
3.135e-02 | -3.46 | GPR42 (G protein-coupled receptor 42) | protein interactions | 2866 | 110 | 2 | 19454 | 49 |
IGFBP5,ATP6V0B |
3.138e-02 | -3.46 | oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor | molecular function | GO:0016668 | 12 | 1 | 18094 | 48 |
TXN |
3.138e-02 | -3.46 | phospholipase inhibitor activity | molecular function | GO:0004859 | 12 | 1 | 18094 | 48 |
SNCA |
3.138e-02 | -3.46 | cytochrome-c oxidase activity | molecular function | GO:0004129 | 12 | 1 | 18094 | 48 |
COX5B |
3.139e-02 | -3.46 | regulation of protein localization | biological process | GO:0032880 | 872 | 6 | 18204 | 50 |
C1QTNF3,RUFY3,OAZ1,SNCA,ACHE,TXN |
3.142e-02 | -3.46 | regulation of carbohydrate biosynthetic process | biological process | GO:0043255 | 101 | 2 | 18204 | 50 |
C1QTNF3,SNCA |
3.142e-02 | -3.46 | filopodium | cellular component | GO:0030175 | 106 | 2 | 19108 | 50 |
GAP43,RUFY3 |
3.165e-02 | -3.45 | IQCB1 (IQ motif containing B1) | protein interactions | 9657 | 274 | 3 | 19454 | 49 |
CNTNAP2,SPINT2,PCP4 |
3.166e-02 | -3.45 | Mab-21 | smart domains | SM01265 | 12 | 1 | 9717 | 26 |
MAB21L1 |
3.166e-02 | -3.45 | DWA | smart domains | SM00523 | 12 | 1 | 9717 | 26 |
NFIB |
3.188e-02 | -3.45 | TMEM120B (transmembrane protein 120B) | protein interactions | 144404 | 111 | 2 | 19454 | 49 |
RTN1,MGST3 |
3.188e-02 | -3.45 | PLP2 (proteolipid protein 2) | protein interactions | 5355 | 111 | 2 | 19454 | 49 |
NDRG4,MGST3 |
3.189e-02 | -3.45 | nucleotide biosynthetic process | biological process | GO:0009165 | 252 | 3 | 18204 | 50 |
NDUFA1,NDUFA5,NDUFB2 |
3.224e-02 | -3.43 | FLNB (filamin B) | protein interactions | 2317 | 276 | 3 | 19454 | 49 |
DUSP23,SNCA,TXN |
3.226e-02 | -3.43 | C11orf24 (chromosome 11 open reading frame 24) | protein interactions | 53838 | 13 | 1 | 19454 | 49 |
MGST3 |
3.226e-02 | -3.43 | FCRL3 (Fc receptor like 3) | protein interactions | 115352 | 13 | 1 | 19454 | 49 |
IGFBP5 |
3.226e-02 | -3.43 | TRPT1 (tRNA phosphotransferase 1) | protein interactions | 83707 | 13 | 1 | 19454 | 49 |
DYNC1LI1 |
3.226e-02 | -3.43 | HSPB6 (heat shock protein family B (small) member 6) | protein interactions | 126393 | 13 | 1 | 19454 | 49 |
SNCA |
3.226e-02 | -3.43 | PGM2L1 (phosphoglucomutase 2 like 1) | protein interactions | 283209 | 13 | 1 | 19454 | 49 |
OAZ1 |
3.226e-02 | -3.43 | MRNIP (MRN complex interacting protein) | protein interactions | 51149 | 13 | 1 | 19454 | 49 |
DUSP23 |
3.241e-02 | -3.43 | UBE2V1 (ubiquitin conjugating enzyme E2 V1) | protein interactions | 7335 | 112 | 2 | 19454 | 49 |
TXN,TAGLN2 |
3.241e-02 | -3.43 | TOMM5 (translocase of outer mitochondrial membrane 5) | protein interactions | 401505 | 112 | 2 | 19454 | 49 |
NDUFA5,MGST3 |
3.248e-02 | -3.43 | neuronal ion channel clustering | biological process | GO:0045161 | 12 | 1 | 18204 | 50 |
CNTNAP2 |
3.248e-02 | -3.43 | mitochondrial electron transport, ubiquinol to cytochrome c | biological process | GO:0006122 | 12 | 1 | 18204 | 50 |
UQCR10 |
3.248e-02 | -3.43 | SNARE complex assembly | biological process | GO:0035493 | 12 | 1 | 18204 | 50 |
SNCA |
3.248e-02 | -3.43 | auditory behavior | biological process | GO:0031223 | 12 | 1 | 18204 | 50 |
CNTNAP2 |
3.248e-02 | -3.43 | regulation of synaptic vesicle membrane organization | biological process | GO:1901632 | 12 | 1 | 18204 | 50 |
SYT1 |
3.248e-02 | -3.43 | regulation of synaptic vesicle fusion to presynaptic active zone membrane | biological process | GO:0031630 | 12 | 1 | 18204 | 50 |
SYT1 |
3.248e-02 | -3.43 | negative regulation of muscle tissue development | biological process | GO:1901862 | 12 | 1 | 18204 | 50 |
IGFBP5 |
3.248e-02 | -3.43 | positive regulation of catecholamine secretion | biological process | GO:0033605 | 12 | 1 | 18204 | 50 |
SYT1 |
3.248e-02 | -3.43 | positive regulation of mitotic cell cycle spindle assembly checkpoint | biological process | GO:0090267 | 12 | 1 | 18204 | 50 |
DYNC1LI1 |
3.248e-02 | -3.43 | neurotransmitter-gated ion channel clustering | biological process | GO:0072578 | 12 | 1 | 18204 | 50 |
RELN |
3.253e-02 | -3.43 | nucleoside phosphate biosynthetic process | biological process | GO:1901293 | 254 | 3 | 18204 | 50 |
NDUFA1,NDUFA5,NDUFB2 |
3.256e-02 | -3.42 | MH1 | pfam domains | PF03165 | 12 | 1 | 17795 | 49 |
NFIB |
3.257e-02 | -3.42 | regulation of neural precursor cell proliferation | biological process | GO:2000177 | 103 | 2 | 18204 | 50 |
SPINT2,CEND1 |
3.276e-02 | -3.42 | SNARE binding | molecular function | GO:0000149 | 107 | 2 | 18094 | 48 |
SYT1,SNCA |
3.282e-02 | -3.42 | GNB2 (G protein subunit beta 2) | protein interactions | 2783 | 482 | 4 | 19454 | 49 |
IGFBP5,MLLT11,GNG3,CLU |
3.283e-02 | -3.42 | MTG2 (mitochondrial ribosome associated GTPase 2) | protein interactions | 26164 | 278 | 3 | 19454 | 49 |
ETFB,RUFY3,NDUFA5 |
3.294e-02 | -3.41 | LRP10 (LDL receptor related protein 10) | protein interactions | 26020 | 113 | 2 | 19454 | 49 |
SPINT2,MGST3 |
3.294e-02 | -3.41 | ARHGAP36 (Rho GTPase activating protein 36) | protein interactions | 158763 | 113 | 2 | 19454 | 49 |
NDUFA5,CLU |
3.308e-02 | -3.41 | cell morphogenesis involved in neuron differentiation | biological process | GO:0048667 | 443 | 4 | 18204 | 50 |
RELN,CCK,GAP43,NFIB |
3.318e-02 | -3.41 | positive regulation of protein kinase activity | biological process | GO:0045860 | 256 | 3 | 18204 | 50 |
SNCA,RELN,TXN |
3.347e-02 | -3.40 | HADH (hydroxyacyl-CoA dehydrogenase) | protein interactions | 3033 | 114 | 2 | 19454 | 49 |
ETFB,TXN |
3.347e-02 | -3.40 | SMS (spermine synthase) | protein interactions | 6611 | 114 | 2 | 19454 | 49 |
SNCA,DYNC1LI1 |
3.373e-02 | -3.39 | gland morphogenesis | biological process | GO:0022612 | 105 | 2 | 18204 | 50 |
IGFBP5,NFIB |
3.373e-02 | -3.39 | neural precursor cell proliferation | biological process | GO:0061351 | 105 | 2 | 18204 | 50 |
NFIB,EMX2 |
3.386e-02 | -3.39 | Olfac-like_dom | interpro domains | IPR003112 | 13 | 1 | 18521 | 49 |
OLFM1 |
3.386e-02 | -3.39 | Carboxylesterase_B_CS | interpro domains | IPR019819 | 13 | 1 | 18521 | 49 |
ACHE |
3.386e-02 | -3.39 | Gprotein-gamma | interpro domains | IPR001770 | 13 | 1 | 18521 | 49 |
GNG3 |
3.389e-02 | -3.38 | human chr1q24.1 | chromosome location | human chr1q24.1 | 18 | 1 | 26134 | 50 |
MGST3 |
3.389e-02 | -3.38 | human chr7q31.32 | chromosome location | human chr7q31.32 | 18 | 1 | 26134 | 50 |
NDUFA5 |
3.395e-02 | -3.38 | oxidoreductase activity, acting on a heme group of donors | molecular function | GO:0016675 | 13 | 1 | 18094 | 48 |
COX5B |
3.395e-02 | -3.38 | insulin-like growth factor I binding | molecular function | GO:0031994 | 13 | 1 | 18094 | 48 |
IGFBP5 |
3.400e-02 | -3.38 | calcium ion binding | molecular function | GO:0005509 | 683 | 5 | 18094 | 48 |
DNER,SYT1,PCP4,CALB2,SNCA |
3.401e-02 | -3.38 | NDUFB5 (NADH:ubiquinone oxidoreductase subunit B5) | protein interactions | 4711 | 115 | 2 | 19454 | 49 |
NDUFA1,NDUFA5 |
3.425e-02 | -3.37 | OLF | smart domains | SM00284 | 13 | 1 | 9717 | 26 |
OLFM1 |
3.446e-02 | -3.37 | The NLRP3 inflammasome | REACTOME pathways | R-HSA-844456 | 12 | 1 | 10285 | 30 |
TXN |
3.455e-02 | -3.37 | FCGRT (Fc gamma receptor and transporter) | protein interactions | 2217 | 116 | 2 | 19454 | 49 |
SEZ6L2,CLU |
3.455e-02 | -3.37 | GLP1R (glucagon like peptide 1 receptor) | protein interactions | 2740 | 116 | 2 | 19454 | 49 |
CEND1,ATP6V0B |
3.455e-02 | -3.37 | RBBP8 (RB binding protein 8, endonuclease) | protein interactions | 5932 | 116 | 2 | 19454 | 49 |
SCOC,CLU |
3.465e-02 | -3.36 | G_PROTEIN_GAMMA | prosite domains | PS50058 | 13 | 1 | 12186 | 33 |
GNG3 |
3.465e-02 | -3.36 | CARBOXYLESTERASE_B_2 | prosite domains | PS00941 | 13 | 1 | 12186 | 33 |
ACHE |
3.465e-02 | -3.36 | OLF | prosite domains | PS51132 | 13 | 1 | 12186 | 33 |
OLFM1 |
3.470e-02 | -3.36 | Stag2 (STAG2 cohesin complex component) | protein interactions | 20843 | 14 | 1 | 19454 | 49 |
CLU |
3.470e-02 | -3.36 | CSF3 (colony stimulating factor 3) | protein interactions | 1440 | 14 | 1 | 19454 | 49 |
NRN1 |
3.470e-02 | -3.36 | ADAP2 (ArfGAP with dual PH domains 2) | protein interactions | 55803 | 14 | 1 | 19454 | 49 |
SNCA |
3.470e-02 | -3.36 | Aifm1 (apoptosis-inducing factor, mitochondrion-associated 1) | protein interactions | 26926 | 14 | 1 | 19454 | 49 |
CLU |
3.470e-02 | -3.36 | Tuba1a (tubulin, alpha 1A) | protein interactions | 22142 | 14 | 1 | 19454 | 49 |
SNCA |
3.470e-02 | -3.36 | C9 (complement C9) | protein interactions | 735 | 14 | 1 | 19454 | 49 |
CLU |
3.470e-02 | -3.36 | CSH2 (chorionic somatomammotropin hormone 2) | protein interactions | 1443 | 14 | 1 | 19454 | 49 |
SCG5 |
3.470e-02 | -3.36 | PLXNA4 (plexin A4) | protein interactions | 91584 | 14 | 1 | 19454 | 49 |
CLU |
3.470e-02 | -3.36 | SYT5 (synaptotagmin 5) | protein interactions | 6861 | 14 | 1 | 19454 | 49 |
SYT1 |
3.470e-02 | -3.36 | AZIN2 (antizyme inhibitor 2) | protein interactions | 113451 | 14 | 1 | 19454 | 49 |
OAZ1 |
3.470e-02 | -3.36 | GRK1 (G protein-coupled receptor kinase 1) | protein interactions | 6011 | 14 | 1 | 19454 | 49 |
SNCA |
3.470e-02 | -3.36 | IGFALS (insulin like growth factor binding protein acid labile subunit) | protein interactions | 3483 | 14 | 1 | 19454 | 49 |
IGFBP5 |
3.470e-02 | -3.36 | CHGA (chromogranin A) | protein interactions | 1113 | 14 | 1 | 19454 | 49 |
SYT1 |
3.475e-02 | -3.36 | axon terminus | cellular component | GO:0043679 | 112 | 2 | 19108 | 50 |
SNCA,CALB2 |
3.486e-02 | -3.36 | Cholinergic synapse | KEGG pathways | hsa04725 | 112 | 2 | 7161 | 19 |
ACHE,GNG3 |
3.514e-02 | -3.35 | positive regulation of inositol phosphate biosynthetic process | biological process | GO:0060732 | 13 | 1 | 18204 | 50 |
SNCA |
3.514e-02 | -3.35 | hypothalamus cell differentiation | biological process | GO:0021979 | 13 | 1 | 18204 | 50 |
NHLH2 |
3.514e-02 | -3.35 | positive regulation of insulin-like growth factor receptor signaling pathway | biological process | GO:0043568 | 13 | 1 | 18204 | 50 |
IGFBP5 |
3.514e-02 | -3.35 | commissural neuron axon guidance | biological process | GO:0071679 | 13 | 1 | 18204 | 50 |
NFIB |
3.514e-02 | -3.35 | negative regulation of amyloid fibril formation | biological process | GO:1905907 | 13 | 1 | 18204 | 50 |
CLU |
3.514e-02 | -3.35 | detection of calcium ion | biological process | GO:0005513 | 13 | 1 | 18204 | 50 |
SYT1 |
3.514e-02 | -3.35 | positive regulation of spindle checkpoint | biological process | GO:0090232 | 13 | 1 | 18204 | 50 |
DYNC1LI1 |
3.514e-02 | -3.35 | branching involved in labyrinthine layer morphogenesis | biological process | GO:0060670 | 13 | 1 | 18204 | 50 |
SPINT2 |
3.514e-02 | -3.35 | negative regulation of homotypic cell-cell adhesion | biological process | GO:0034111 | 13 | 1 | 18204 | 50 |
CD9 |
3.514e-02 | -3.35 | prepulse inhibition | biological process | GO:0060134 | 13 | 1 | 18204 | 50 |
CNTNAP2 |
3.514e-02 | -3.35 | telencephalon regionalization | biological process | GO:0021978 | 13 | 1 | 18204 | 50 |
EMX2 |
3.514e-02 | -3.35 | positive regulation of calcium ion-dependent exocytosis | biological process | GO:0045956 | 13 | 1 | 18204 | 50 |
SYT1 |
3.514e-02 | -3.35 | negative regulation of microtubule polymerization | biological process | GO:0031115 | 13 | 1 | 18204 | 50 |
SNCA |
3.514e-02 | -3.35 | cerebellar granular layer development | biological process | GO:0021681 | 13 | 1 | 18204 | 50 |
CEND1 |
3.514e-02 | -3.35 | cerebellar Purkinje cell differentiation | biological process | GO:0021702 | 13 | 1 | 18204 | 50 |
CEND1 |
3.514e-02 | -3.35 | thalamus development | biological process | GO:0021794 | 13 | 1 | 18204 | 50 |
CNTNAP2 |
3.514e-02 | -3.35 | glial cell fate commitment | biological process | GO:0021781 | 13 | 1 | 18204 | 50 |
NFIB |
3.514e-02 | -3.35 | motor neuron migration | biological process | GO:0097475 | 13 | 1 | 18204 | 50 |
RELN |
3.514e-02 | -3.35 | negative regulation of monooxygenase activity | biological process | GO:0032769 | 13 | 1 | 18204 | 50 |
SNCA |
3.522e-02 | -3.35 | OLF | pfam domains | PF02191 | 13 | 1 | 17795 | 49 |
OLFM1 |
3.545e-02 | -3.34 | VDAC1 (voltage dependent anion channel 1) | protein interactions | 7416 | 494 | 4 | 19454 | 49 |
TXN,MGST3,SNCA,NDUFA5 |
3.574e-02 | -3.33 | human chr7p21.3 | chromosome location | human chr7p21.3 | 19 | 1 | 26134 | 50 |
THSD7A |
3.596e-02 | -3.33 | purine nucleotide metabolic process | biological process | GO:0006163 | 455 | 4 | 18204 | 50 |
PDE4B,NDUFB2,NDUFA5,NDUFA1 |
3.599e-02 | -3.32 | Metabolic pathways | KEGG pathways | hsa01100 | 1256 | 7 | 7161 | 19 |
NDUFA5,COX5B,UQCR10,ATP6V0B,NDUFA1,NDUFB2,COX6A1 |
3.620e-02 | -3.32 | KLHL22 (kelch like family member 22) | protein interactions | 84861 | 119 | 2 | 19454 | 49 |
SPINT2,DYNC1LI1 |
3.634e-02 | -3.31 | tube development | biological process | GO:0035295 | 903 | 6 | 18204 | 50 |
THSD7A,NDRG4,EMX2,SPINT2,IGFBP5,NFIB |
3.642e-02 | -3.31 | Neurexin-like | interpro domains | IPR003585 | 14 | 1 | 18521 | 49 |
CNTNAP2 |
3.642e-02 | -3.31 | CarbesteraseB | interpro domains | IPR002018 | 14 | 1 | 18521 | 49 |
ACHE |
3.650e-02 | -3.31 | Metabolism of proteins | REACTOME pathways | R-HSA-392499 | 1619 | 9 | 10285 | 30 |
SNCA,IGFBP5,GNG3,THSD7A,DYNC1LI1,NRN1,TXN,ACHE,ETFB |
3.652e-02 | -3.31 | TCF4 (transcription factor 4) | protein interactions | 6925 | 290 | 3 | 19454 | 49 |
SCOC,DUSP23,NHLH2 |
3.654e-02 | -3.31 | NADH dehydrogenase (ubiquinone) 1 beta subcomplex | KEGG pathways | M00147 | 14 | 1 | 7161 | 19 |
NDUFB2 |
3.654e-02 | -3.31 | NADH dehydrogenase (ubiquinone) 1 beta subcomplex | KEGG pathways | hsa_M00147 | 14 | 1 | 7161 | 19 |
NDUFB2 |
3.671e-02 | -3.30 | GPROTEING | prints domains | PR00321 | 13 | 1 | 5227 | 15 |
GNG3 |
3.676e-02 | -3.30 | FHL1 (four and a half LIM domains 1) | protein interactions | 2273 | 120 | 2 | 19454 | 49 |
IGFBP5,SNCA |
3.684e-02 | -3.30 | 4.1m | smart domains | SM00294 | 14 | 1 | 9717 | 26 |
CNTNAP2 |
3.688e-02 | -3.30 | plasma membrane bounded cell projection organization | biological process | GO:0120036 | 1152 | 7 | 18204 | 50 |
CNTNAP2,NRN1,DUSP23,NFIB,GAP43,RELN,CCK |
3.709e-02 | -3.29 | HNRNPH1 (heterogeneous nuclear ribonucleoprotein H1) | protein interactions | 3187 | 1539 | 8 | 19454 | 49 |
CEND1,SCOC,SNCA,GNG3,NDUFB2,OAZ1,CD9,NDRG4 |
3.713e-02 | -3.29 | alpha/beta hydrolase | gene3d domains | 3.40.50.1820 | 116 | 2 | 14470 | 38 |
ACHE,NDRG4 |
3.714e-02 | -3.29 | NPR1 (natriuretic peptide receptor 1) | protein interactions | 4881 | 15 | 1 | 19454 | 49 |
TXN |
3.714e-02 | -3.29 | ABHD4 (abhydrolase domain containing 4, N-acyl phospholipase B) | protein interactions | 63874 | 15 | 1 | 19454 | 49 |
IGFBP5 |
3.714e-02 | -3.29 | MEP1B (meprin A subunit beta) | protein interactions | 4225 | 15 | 1 | 19454 | 49 |
CCK |
3.714e-02 | -3.29 | RNASE13 (ribonuclease A family member 13 (inactive)) | protein interactions | 440163 | 15 | 1 | 19454 | 49 |
CLU |
3.714e-02 | -3.29 | LEMD1 (LEM domain containing 1) | protein interactions | 93273 | 15 | 1 | 19454 | 49 |
MGST3 |
3.715e-02 | -3.29 | NDUFS7 (NADH:ubiquinone oxidoreductase core subunit S7) | protein interactions | 374291 | 292 | 3 | 19454 | 49 |
NDUFA5,NDUFA1,MGST3 |
3.732e-02 | -3.29 | ARL6IP1 (ADP ribosylation factor like GTPase 6 interacting protein 1) | protein interactions | 23204 | 121 | 2 | 19454 | 49 |
MGST3,NDRG4 |
3.747e-02 | -3.28 | PDIA6 (protein disulfide isomerase family A member 6) | protein interactions | 10130 | 293 | 3 | 19454 | 49 |
IGFBP5,DUSP23,PDE4B |
3.755e-02 | -3.28 | intracellular membrane-bounded organelle | cellular component | GO:0043231 | 12479 | 39 | 19108 | 50 |
PDE4B,DUSP23,DNER,SEZ6L2,PCP4,NDUFA5,NHLH2,TXN,OLFM1,COX5B,ETFB,ISOC1,RTN1,CHD5,NDRG4,SCOC,DYNC1LI1,SNCA,CD9,ATP6V0B,MAB21L1,MLLT11,COX6A1,NDUFB2,IGFBP5,CEND1,OAZ1,CNTNAP2,UQCR10,SH3BGRL3,CLU,NFIB,SYT1,EMX2,ACHE,MGST3,CALB2,SCG5,NDUFA1 |
3.759e-02 | -3.28 | human chr3p22.3 | chromosome location | human chr3p22.3 | 20 | 1 | 26134 | 50 |
DYNC1LI1 |
3.759e-02 | -3.28 | human chr8p21.1 | chromosome location | human chr8p21.1 | 20 | 1 | 26134 | 50 |
CLU |
3.779e-02 | -3.28 | synaptic vesicle priming | biological process | GO:0016082 | 14 | 1 | 18204 | 50 |
SNCA |
3.779e-02 | -3.28 | cyclic nucleotide catabolic process | biological process | GO:0009214 | 14 | 1 | 18204 | 50 |
PDE4B |
3.779e-02 | -3.28 | interneuron migration | biological process | GO:1904936 | 14 | 1 | 18204 | 50 |
RELN |
3.779e-02 | -3.28 | radial glial cell differentiation | biological process | GO:0060019 | 14 | 1 | 18204 | 50 |
GAP43 |
3.779e-02 | -3.28 | regulation of relaxation of muscle | biological process | GO:1901077 | 14 | 1 | 18204 | 50 |
PDE4B |
3.779e-02 | -3.28 | regulation of skeletal muscle adaptation | biological process | GO:0014733 | 14 | 1 | 18204 | 50 |
IGFBP5 |
3.779e-02 | -3.28 | layer formation in cerebral cortex | biological process | GO:0021819 | 14 | 1 | 18204 | 50 |
RELN |
3.779e-02 | -3.28 | regulation of sulfur metabolic process | biological process | GO:0042762 | 14 | 1 | 18204 | 50 |
SNCA |
3.779e-02 | -3.28 | regulation of protein complex stability | biological process | GO:0061635 | 14 | 1 | 18204 | 50 |
SCOC |
3.779e-02 | -3.28 | negative regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway | biological process | GO:0106072 | 14 | 1 | 18204 | 50 |
PDE4B |
3.779e-02 | -3.28 | endosomal lumen acidification | biological process | GO:0048388 | 14 | 1 | 18204 | 50 |
ATP6V0B |
3.779e-02 | -3.28 | regulation of SNARE complex assembly | biological process | GO:0035542 | 14 | 1 | 18204 | 50 |
SNCA |
3.779e-02 | -3.28 | polyamine biosynthetic process | biological process | GO:0006596 | 14 | 1 | 18204 | 50 |
OAZ1 |
3.779e-02 | -3.28 | regulation of NMDA receptor activity | biological process | GO:2000310 | 14 | 1 | 18204 | 50 |
RELN |
3.779e-02 | -3.28 | mechanosensory behavior | biological process | GO:0007638 | 14 | 1 | 18204 | 50 |
CNTNAP2 |
3.779e-02 | -3.28 | positive regulation of receptor recycling | biological process | GO:0001921 | 14 | 1 | 18204 | 50 |
SNCA |
3.788e-02 | -3.27 | COesterase | pfam domains | PF00135 | 14 | 1 | 17795 | 49 |
ACHE |
3.794e-02 | -3.27 | regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction | biological process | GO:0051896 | 270 | 3 | 18204 | 50 |
TXN,RELN,IGFBP5 |
3.795e-02 | -3.27 | unfolded protein binding | molecular function | GO:0051082 | 116 | 2 | 18094 | 48 |
SCG5,CLU |
3.844e-02 | -3.26 | YIF1A (Yip1 interacting factor homolog A, membrane trafficking protein) | protein interactions | 10897 | 123 | 2 | 19454 | 49 |
MGST3,NDRG4 |
3.855e-02 | -3.26 | axolemma | cellular component | GO:0030673 | 15 | 1 | 19108 | 50 |
CNTNAP2 |
3.868e-02 | -3.25 | regulation of locomotion | biological process | GO:0040012 | 1164 | 7 | 18204 | 50 |
SPINT2,RELN,SNCA,IGFBP5,CD9,NDRG4,RUFY3 |
3.869e-02 | -3.25 | - | gene3d domains | 4.10.40.20 | 15 | 1 | 14470 | 38 |
IGFBP5 |
3.897e-02 | -3.24 | AB_hydrolase | interpro domains | IPR029058 | 118 | 2 | 18521 | 49 |
ACHE,NDRG4 |
3.908e-02 | -3.24 | carbon-sulfur lyase activity | molecular function | GO:0016846 | 15 | 1 | 18094 | 48 |
MGST3 |
3.915e-02 | -3.24 | tube morphogenesis | biological process | GO:0035239 | 685 | 5 | 18204 | 50 |
NDRG4,THSD7A,SPINT2,NFIB,EMX2 |
3.942e-02 | -3.23 | PDHB (pyruvate dehydrogenase E1 subunit beta) | protein interactions | 5162 | 299 | 3 | 19454 | 49 |
DYNC1LI1,NDUFA5,MGST3 |
3.943e-02 | -3.23 | human chr15q13.3 | chromosome location | human chr15q13.3 | 21 | 1 | 26134 | 50 |
SCG5 |
3.943e-02 | -3.23 | human chr10q26.11 | chromosome location | human chr10q26.11 | 21 | 1 | 26134 | 50 |
EMX2 |
3.956e-02 | -3.23 | import into cell | biological process | GO:0098657 | 687 | 5 | 18204 | 50 |
SYT1,ACHE,DNER,SNCA,CD9 |
3.956e-02 | -3.23 | Dync1h1 (dynein cytoplasmic 1 heavy chain 1) | protein interactions | 13424 | 16 | 1 | 19454 | 49 |
DYNC1LI1 |
3.956e-02 | -3.23 | NRGN (neurogranin) | protein interactions | 4900 | 16 | 1 | 19454 | 49 |
SNCA |
3.956e-02 | -3.23 | SYT4 (synaptotagmin 4) | protein interactions | 6860 | 16 | 1 | 19454 | 49 |
SYT1 |
3.956e-02 | -3.23 | CDC42SE1 (CDC42 small effector 1) | protein interactions | 56882 | 16 | 1 | 19454 | 49 |
SNCA |
3.956e-02 | -3.23 | RBM18 (RNA binding motif protein 18) | protein interactions | 92400 | 16 | 1 | 19454 | 49 |
SYT1 |
3.956e-02 | -3.23 | MX2 (MX dynamin like GTPase 2) | protein interactions | 4600 | 16 | 1 | 19454 | 49 |
TXN |
3.956e-02 | -3.23 | RHCG (Rh family C glycoprotein) | protein interactions | 51458 | 16 | 1 | 19454 | 49 |
IGFBP5 |
3.985e-02 | -3.22 | FOXA1 (forkhead box A1) | protein interactions | 3169 | 513 | 4 | 19454 | 49 |
SH3BGRL3,UQCR10,NFIB,SEZ6L2 |
4.008e-02 | -3.22 | learning or memory | biological process | GO:0007611 | 276 | 3 | 18204 | 50 |
RELN,NDRG4,CNTNAP2 |
4.016e-02 | -3.21 | SERPINA3 (serpin family A member 3) | protein interactions | 12 | 126 | 2 | 19454 | 49 |
CLU,PCP4 |
4.043e-02 | -3.21 | exit from mitosis | biological process | GO:0010458 | 15 | 1 | 18204 | 50 |
NFIB |
4.043e-02 | -3.21 | regulation of presynaptic cytosolic calcium ion concentration | biological process | GO:0099509 | 15 | 1 | 18204 | 50 |
CALB2 |
4.043e-02 | -3.21 | regulation of inositol phosphate biosynthetic process | biological process | GO:0010919 | 15 | 1 | 18204 | 50 |
SNCA |
4.043e-02 | -3.21 | synapse maturation | biological process | GO:0060074 | 15 | 1 | 18204 | 50 |
SEZ6L2 |
4.043e-02 | -3.21 | heart valve formation | biological process | GO:0003188 | 15 | 1 | 18204 | 50 |
OLFM1 |
4.043e-02 | -3.21 | cerebellar Purkinje cell layer formation | biological process | GO:0021694 | 15 | 1 | 18204 | 50 |
CEND1 |
4.074e-02 | -3.20 | NDUFA13 (NADH:ubiquinone oxidoreductase subunit A13) | protein interactions | 51079 | 127 | 2 | 19454 | 49 |
NDUFA5,NDUFA1 |
4.074e-02 | -3.20 | AUH (AU RNA binding methylglutaconyl-CoA hydratase) | protein interactions | 549 | 303 | 3 | 19454 | 49 |
ETFB,NDUFA5,COX5B |
4.107e-02 | -3.19 | cellular detoxification | biological process | GO:1990748 | 117 | 2 | 18204 | 50 |
MGST3,TXN |
4.107e-02 | -3.19 | CHD-type complex | cellular component | GO:0090545 | 16 | 1 | 19108 | 50 |
CHD5 |
4.107e-02 | -3.19 | NuRD complex | cellular component | GO:0016581 | 16 | 1 | 19108 | 50 |
CHD5 |
4.120e-02 | -3.19 | intracellular anatomical structure | cellular component | GO:0005622 | 15205 | 45 | 19108 | 50 |
COX5B,RTN1,ISOC1,TXN,NDUFA5,CD9,SNCA,COX6A1,MAB21L1,TSTD1,NDRG4,SCOC,CALB2,ACHE,EMX2,RUFY3,SCG5,NDUFB2,TAGLN2,CLU,NFIB,SH3BGRL3,CNTNAP2,OAZ1,DNER,RELN,DUSP23,PDE4B,ETFB,OLFM1,GAP43,SEZ6L2,PCP4,NHLH2,MLLT11,ATP6V0B,CHD5,DYNC1LI1,SPINT2,MGST3,SYT1,NDUFA1,CEND1,IGFBP5,UQCR10 |
4.127e-02 | -3.19 | human chr2q36.3 | chromosome location | human chr2q36.3 | 22 | 1 | 26134 | 50 |
DNER |
4.127e-02 | -3.19 | human chr1p13.1 | chromosome location | human chr1p13.1 | 22 | 1 | 26134 | 50 |
NHLH2 |
4.127e-02 | -3.19 | human chr3q13.31 | chromosome location | human chr3q13.31 | 22 | 1 | 26134 | 50 |
GAP43 |
4.132e-02 | -3.19 | MAP4K1 (mitogen-activated protein kinase kinase kinase kinase 1) | protein interactions | 11184 | 128 | 2 | 19454 | 49 |
MLLT11,NDUFA5 |
4.163e-02 | -3.18 | misfolded protein binding | molecular function | GO:0051787 | 16 | 1 | 18094 | 48 |
CLU |
4.163e-02 | -3.18 | lipase inhibitor activity | molecular function | GO:0055102 | 16 | 1 | 18094 | 48 |
SNCA |
4.163e-02 | -3.18 | dynein heavy chain binding | molecular function | GO:0045504 | 16 | 1 | 18094 | 48 |
DYNC1LI1 |
4.170e-02 | -3.18 | synapse assembly | biological process | GO:0007416 | 118 | 2 | 18204 | 50 |
ACHE,DNER |
4.190e-02 | -3.17 | PNKP (polynucleotide kinase 3'-phosphatase) | protein interactions | 11284 | 129 | 2 | 19454 | 49 |
SNCA,EMX2 |
4.198e-02 | -3.17 | CNTN2 (contactin 2) | protein interactions | 6900 | 17 | 1 | 19454 | 49 |
CNTNAP2 |
4.198e-02 | -3.17 | Dynlrb1 (dynein light chain roadblock-type 1) | protein interactions | 67068 | 17 | 1 | 19454 | 49 |
DYNC1LI1 |
4.198e-02 | -3.17 | TMEM45A (transmembrane protein 45A) | protein interactions | 55076 | 17 | 1 | 19454 | 49 |
IGFBP5 |
4.198e-02 | -3.17 | IGH (immunoglobulin heavy locus) | protein interactions | 3492 | 17 | 1 | 19454 | 49 |
SNCA |
4.198e-02 | -3.17 | CLDN9 (claudin 9) | protein interactions | 9080 | 17 | 1 | 19454 | 49 |
IGFBP5 |
4.198e-02 | -3.17 | CDC42EP3 (CDC42 effector protein 3) | protein interactions | 10602 | 17 | 1 | 19454 | 49 |
SNCA |
4.198e-02 | -3.17 | EIF5AL1 (eukaryotic translation initiation factor 5A like 1) | protein interactions | 143244 | 17 | 1 | 19454 | 49 |
TAGLN2 |
4.198e-02 | -3.17 | Ctnnb1 (catenin beta 1) | protein interactions | 12387 | 17 | 1 | 19454 | 49 |
SNCA |
4.198e-02 | -3.17 | ARPP19 (cAMP regulated phosphoprotein 19) | protein interactions | 10776 | 17 | 1 | 19454 | 49 |
SNCA |
4.239e-02 | -3.16 | perinuclear region of cytoplasm | cellular component | GO:0048471 | 735 | 5 | 19108 | 50 |
ACHE,SNCA,TSTD1,PDE4B,CLU |
4.249e-02 | -3.16 | BPTI_KUNITZ_1 | prosite domains | PS00280 | 16 | 1 | 12186 | 33 |
SPINT2 |
4.249e-02 | -3.16 | FA58C_2 | prosite domains | PS01286 | 16 | 1 | 12186 | 33 |
CNTNAP2 |
4.249e-02 | -3.16 | NDUFB10 (NADH:ubiquinone oxidoreductase subunit B10) | protein interactions | 4716 | 130 | 2 | 19454 | 49 |
NDUFA5,NDUFA1 |
4.249e-02 | -3.16 | NDUFB9 (NADH:ubiquinone oxidoreductase subunit B9) | protein interactions | 4715 | 130 | 2 | 19454 | 49 |
NDUFA5,NDUFA1 |
4.249e-02 | -3.16 | CLIC4 (chloride intracellular channel 4) | protein interactions | 25932 | 130 | 2 | 19454 | 49 |
TAGLN2,SNCA |
4.283e-02 | -3.15 | central_nervous_system-brainstem-glioma-astrocytoma_Grade_III | COSMIC cancer mutations | central_nervous_system-brainstem-glioma-astrocytoma_Grade_III | 113 | 2 | 16828 | 49 |
RELN,TAGLN2 |
4.299e-02 | -3.15 | regulation of peptidyl-serine phosphorylation | biological process | GO:0033135 | 120 | 2 | 18204 | 50 |
SNCA,TXN |
4.304e-02 | -3.15 | EZR (ezrin) | protein interactions | 7430 | 526 | 4 | 19454 | 49 |
DYNC1LI1,SNCA,RTN1,TAGLN2 |
4.307e-02 | -3.14 | regulation of postsynaptic specialization assembly | biological process | GO:0099150 | 16 | 1 | 18204 | 50 |
GAP43 |
4.307e-02 | -3.14 | positive regulation of CREB transcription factor activity | biological process | GO:0032793 | 16 | 1 | 18204 | 50 |
RELN |
4.307e-02 | -3.14 | neutrophil homeostasis | biological process | GO:0001780 | 16 | 1 | 18204 | 50 |
PDE4B |
4.307e-02 | -3.14 | osteoblast development | biological process | GO:0002076 | 16 | 1 | 18204 | 50 |
ACHE |
4.308e-02 | -3.14 | OLA1 (Obg like ATPase 1) | protein interactions | 29789 | 131 | 2 | 19454 | 49 |
SNCA,TXN |
4.308e-02 | -3.14 | ENO2 (enolase 2) | protein interactions | 2026 | 131 | 2 | 19454 | 49 |
TXN,TAGLN2 |
4.308e-02 | -3.14 | AHNAK2 (AHNAK nucleoprotein 2) | protein interactions | 113146 | 131 | 2 | 19454 | 49 |
DUSP23,IGFBP5 |
4.313e-02 | -3.14 | Glutaredoxin | gene3d domains | 3.40.30.10 | 126 | 2 | 14470 | 38 |
TXN,SH3BGRL3 |
4.324e-02 | -3.14 | purine-containing compound metabolic process | biological process | GO:0072521 | 483 | 4 | 18204 | 50 |
PDE4B,NDUFB2,NDUFA5,NDUFA1 |
4.340e-02 | -3.14 | cell junction assembly | biological process | GO:0034329 | 285 | 3 | 18204 | 50 |
DNER,CD9,ACHE |
4.352e-02 | -3.13 | homeostatic process | biological process | GO:0042592 | 1456 | 8 | 18204 | 50 |
TXN,SNCA,IGFBP5,NFIB,ATP6V0B,CALB2,PDE4B,C1QTNF3 |
4.358e-02 | -3.13 | apical dendrite | cellular component | GO:0097440 | 17 | 1 | 19108 | 50 |
CLU |
4.367e-02 | -3.13 | BAX (BCL2 associated X, apoptosis regulator) | protein interactions | 581 | 132 | 2 | 19454 | 49 |
SNCA,CLU |
4.367e-02 | -3.13 | FASTKD3 (FAST kinase domains 3) | protein interactions | 79072 | 132 | 2 | 19454 | 49 |
NDUFA5,ETFB |
4.368e-02 | -3.13 | Effects of Botulinum toxin | Pathway Interaction DB | botulinumtoxinpathway | 9 | 1 | 2226 | 11 |
SYT1 |
4.374e-02 | -3.13 | Transducin (heterotrimeric G protein), gamma chain | gene3d domains | 4.10.260.10 | 17 | 1 | 14470 | 38 |
GNG3 |
4.374e-02 | -3.13 | - | gene3d domains | 1.10.1410.40 | 17 | 1 | 14470 | 38 |
MAB21L1 |
4.374e-02 | -3.13 | Thyroglobulin type-1 | gene3d domains | 4.10.800.10 | 17 | 1 | 14470 | 38 |
IGFBP5 |
4.374e-02 | -3.13 | - | gene3d domains | 2.60.120.1000 | 17 | 1 | 14470 | 38 |
CNTNAP2 |
4.377e-02 | -3.13 | developmental maturation | biological process | GO:0021700 | 286 | 3 | 18204 | 50 |
CNTNAP2,CEND1,SEZ6L2 |
4.379e-02 | -3.13 | regulation of transmembrane transport | biological process | GO:0034762 | 485 | 4 | 18204 | 50 |
RELN,PDE4B,SNCA,OAZ1 |
4.381e-02 | -3.13 | RTN4 (reticulon 4) | protein interactions | 57142 | 312 | 3 | 19454 | 49 |
RTN1,COX5B,SNCA |
4.406e-02 | -3.12 | Synaptotagmin | interpro domains | IPR001565 | 17 | 1 | 18521 | 49 |
SYT1 |
4.406e-02 | -3.12 | G-protein_gamma-like_dom | interpro domains | IPR015898 | 17 | 1 | 18521 | 49 |
GNG3 |
4.406e-02 | -3.12 | Thioredoxin_CS | interpro domains | IPR017937 | 17 | 1 | 18521 | 49 |
TXN |
4.406e-02 | -3.12 | GGL_sf | interpro domains | IPR036284 | 17 | 1 | 18521 | 49 |
GNG3 |
4.406e-02 | -3.12 | Prtase_inh_Kunz-CS | interpro domains | IPR020901 | 17 | 1 | 18521 | 49 |
SPINT2 |
4.406e-02 | -3.12 | Thyroglobulin_1_sf | interpro domains | IPR036857 | 17 | 1 | 18521 | 49 |
IGFBP5 |
4.406e-02 | -3.12 | Thyroglobulin_1 | interpro domains | IPR000716 | 17 | 1 | 18521 | 49 |
IGFBP5 |
4.440e-02 | -3.11 | CYP2E1 (cytochrome P450 family 2 subfamily E member 1) | protein interactions | 1571 | 18 | 1 | 19454 | 49 |
CLU |
4.440e-02 | -3.11 | Gnb1 (guanine nucleotide binding protein (G protein), beta 1) | protein interactions | 14688 | 18 | 1 | 19454 | 49 |
SNCA |
4.440e-02 | -3.11 | TKTL2 (transketolase like 2) | protein interactions | 84076 | 18 | 1 | 19454 | 49 |
TAGLN2 |
4.440e-02 | -3.11 | TSPAN1 (tetraspanin 1) | protein interactions | 10103 | 18 | 1 | 19454 | 49 |
CD9 |
4.440e-02 | -3.11 | RELN (reelin) | protein interactions | 5649 | 18 | 1 | 19454 | 49 |
RELN |
4.440e-02 | -3.11 | CMC2 (C-X9-C motif containing 2) | protein interactions | 56942 | 18 | 1 | 19454 | 49 |
COX5B |
4.440e-02 | -3.11 | CYTB (cytochrome b) | protein interactions | 4519 | 18 | 1 | 19454 | 49 |
UQCR10 |
4.445e-02 | -3.11 | cell projection organization | biological process | GO:0030030 | 1200 | 7 | 18204 | 50 |
DUSP23,CCK,NRN1,CNTNAP2,GAP43,RELN,NFIB |
4.450e-02 | -3.11 | Thioredoxin-like_sf | interpro domains | IPR036249 | 127 | 2 | 18521 | 49 |
SH3BGRL3,TXN |
4.456e-02 | -3.11 | G_gamma | smart domains | SM01224 | 17 | 1 | 9717 | 26 |
GNG3 |
4.456e-02 | -3.11 | RUN | smart domains | SM00593 | 17 | 1 | 9717 | 26 |
RUFY3 |
4.456e-02 | -3.11 | GGL | smart domains | SM00224 | 17 | 1 | 9717 | 26 |
GNG3 |
4.456e-02 | -3.11 | KU | smart domains | SM00131 | 17 | 1 | 9717 | 26 |
SPINT2 |
4.456e-02 | -3.11 | TY | smart domains | SM00211 | 17 | 1 | 9717 | 26 |
IGFBP5 |
4.487e-02 | -3.10 | H3-7 (H3.7 histone (putative)) | protein interactions | 440686 | 134 | 2 | 19454 | 49 |
EMX2,RTN1 |
4.492e-02 | -3.10 | muscle cell differentiation | biological process | GO:0042692 | 289 | 3 | 18204 | 50 |
IGFBP5,DNER,CD9 |
4.494e-02 | -3.10 | human chr16q22.2 | chromosome location | human chr16q22.2 | 24 | 1 | 26134 | 50 |
CALB2 |
4.500e-02 | -3.10 | BASICPTASE | prints domains | PR00759 | 16 | 1 | 5227 | 15 |
SPINT2 |
4.508e-02 | -3.10 | THIOREDOXIN_1 | prosite domains | PS00194 | 17 | 1 | 12186 | 33 |
TXN |
4.508e-02 | -3.10 | THYROGLOBULIN_1_1 | prosite domains | PS00484 | 17 | 1 | 12186 | 33 |
IGFBP5 |
4.508e-02 | -3.10 | THYROGLOBULIN_1_2 | prosite domains | PS51162 | 17 | 1 | 12186 | 33 |
IGFBP5 |
4.547e-02 | -3.09 | SOX15 (SRY-box transcription factor 15) | protein interactions | 6665 | 135 | 2 | 19454 | 49 |
CHD5,NFIB |
4.558e-02 | -3.09 | cellular process | biological process | GO:0009987 | 14996 | 46 | 18204 | 50 |
TAGLN2,SPINT2,EMX2,GAP43,NFIB,MAB21L1,NDUFB2,PDE4B,CHD5,SCG5,MLLT11,C1QTNF3,SNCA,TXN,CEND1,NDUFA5,SH3BGRL3,RELN,NDRG4,DUSP23,CCK,MGST3,RUFY3,NDUFA1,UQCR10,ATP6V0B,ETFB,NHLH2,ACHE,DNER,COX5B,CNTNAP2,OLFM1,COX6A1,DYNC1LI1,CLU,PCP4,SEZ6L2,IGFBP5,RTN1,SYT1,GNG3,THSD7A,CD9,NRN1,TSTD1 |
4.570e-02 | -3.09 | sperm DNA condensation | biological process | GO:0035092 | 17 | 1 | 18204 | 50 |
CHD5 |
4.570e-02 | -3.09 | reverse cholesterol transport | biological process | GO:0043691 | 17 | 1 | 18204 | 50 |
CLU |
4.570e-02 | -3.09 | regulation of inclusion body assembly | biological process | GO:0090083 | 17 | 1 | 18204 | 50 |
CLU |
4.570e-02 | -3.09 | ureter development | biological process | GO:0072189 | 17 | 1 | 18204 | 50 |
EMX2 |
4.570e-02 | -3.09 | regulation of amyloid fibril formation | biological process | GO:1905906 | 17 | 1 | 18204 | 50 |
CLU |
4.570e-02 | -3.09 | endoplasmic reticulum tubular network organization | biological process | GO:0071786 | 17 | 1 | 18204 | 50 |
RTN1 |
4.570e-02 | -3.09 | synaptic transmission, dopaminergic | biological process | GO:0001963 | 17 | 1 | 18204 | 50 |
SNCA |
4.573e-02 | -3.09 | haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-mantle_cell_lymphoma | COSMIC cancer mutations | haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-mantle_cell_lymphoma | 2737 | 13 | 16828 | 49 |
CNTNAP2,SYT1,SNCA,THSD7A,CALB2,RTN1,PDE4B,RELN,DNER,CCK,ETFB,NFIB,OLFM1 |
4.577e-02 | -3.08 | Growth_fac_rcpt_cys_sf | interpro domains | IPR009030 | 129 | 2 | 18521 | 49 |
IGFBP5,DNER |
4.581e-02 | -3.08 | G-gamma | pfam domains | PF00631 | 17 | 1 | 17795 | 49 |
GNG3 |
4.581e-02 | -3.08 | Thyroglobulin_1 | pfam domains | PF00086 | 17 | 1 | 17795 | 49 |
IGFBP5 |
4.608e-02 | -3.08 | RAP1GDS1 (Rap1 GTPase-GDP dissociation stimulator 1) | protein interactions | 5910 | 136 | 2 | 19454 | 49 |
DUSP23,ETFB |
4.608e-02 | -3.08 | RABAC1 (Rab acceptor 1) | protein interactions | 10567 | 136 | 2 | 19454 | 49 |
SNCA,NDRG4 |
4.609e-02 | -3.08 | filopodium membrane | cellular component | GO:0031527 | 18 | 1 | 19108 | 50 |
GAP43 |
4.626e-02 | -3.07 | - | gene3d domains | 1.20.58.900 | 18 | 1 | 14470 | 38 |
RUFY3 |
4.626e-02 | -3.07 | Pancreatic trypsin inhibitor Kunitz domain | gene3d domains | 4.10.410.10 | 18 | 1 | 14470 | 38 |
SPINT2 |
4.659e-02 | -3.07 | Run_dom_sf | interpro domains | IPR037213 | 18 | 1 | 18521 | 49 |
RUFY3 |
4.659e-02 | -3.07 | Run_dom | interpro domains | IPR004012 | 18 | 1 | 18521 | 49 |
RUFY3 |
4.659e-02 | -3.07 | Kunitz_BPTI | interpro domains | IPR002223 | 18 | 1 | 18521 | 49 |
SPINT2 |
4.659e-02 | -3.07 | Kunitz_BPTI_sf | interpro domains | IPR036880 | 18 | 1 | 18521 | 49 |
SPINT2 |
4.669e-02 | -3.06 | NUP85 (nucleoporin 85) | protein interactions | 79902 | 137 | 2 | 19454 | 49 |
SNCA,DYNC1LI1 |
4.669e-02 | -3.06 | GNA13 (G protein subunit alpha 13) | protein interactions | 10672 | 137 | 2 | 19454 | 49 |
ISOC1,GNG3 |
4.677e-02 | -3.06 | human chr1p36.31 | chromosome location | human chr1p36.31 | 25 | 1 | 26134 | 50 |
CHD5 |
4.677e-02 | -3.06 | synaptic vesicle membrane | cellular component | GO:0030672 | 132 | 2 | 19108 | 50 |
SYT1,SNCA |
4.677e-02 | -3.06 | exocytic vesicle membrane | cellular component | GO:0099501 | 132 | 2 | 19108 | 50 |
SYT1,SNCA |
4.681e-02 | -3.06 | FUOM (fucose mutarotase) | protein interactions | 282969 | 19 | 1 | 19454 | 49 |
DUSP23 |
4.681e-02 | -3.06 | LRRC52 (leucine rich repeat containing 52) | protein interactions | 440699 | 19 | 1 | 19454 | 49 |
NRN1 |
4.681e-02 | -3.06 | GNAT2 (G protein subunit alpha transducin 2) | protein interactions | 2780 | 19 | 1 | 19454 | 49 |
GNG3 |
4.681e-02 | -3.06 | HBEGF (heparin binding EGF like growth factor) | protein interactions | 1839 | 19 | 1 | 19454 | 49 |
CD9 |
4.681e-02 | -3.06 | C6orf62 (chromosome 6 open reading frame 62) | protein interactions | 81688 | 19 | 1 | 19454 | 49 |
COX5B |
4.681e-02 | -3.06 | PLCB2 (phospholipase C beta 2) | protein interactions | 5330 | 19 | 1 | 19454 | 49 |
SNCA |
4.681e-02 | -3.06 | GNAL (G protein subunit alpha L) | protein interactions | 2774 | 19 | 1 | 19454 | 49 |
SNCA |
4.681e-02 | -3.06 | TEX12 (testis expressed 12) | protein interactions | 56158 | 19 | 1 | 19454 | 49 |
COX5B |
4.681e-02 | -3.06 | Tubb5 (tubulin, beta 5 class I) | protein interactions | 22154 | 19 | 1 | 19454 | 49 |
SNCA |
4.681e-02 | -3.06 | FBXO27 (F-box protein 27) | protein interactions | 126433 | 19 | 1 | 19454 | 49 |
CLU |
4.691e-02 | -3.06 | molecular function inhibitor activity | molecular function | GO:0140678 | 514 | 4 | 18094 | 48 |
SPINT2,SCG5,OAZ1,SNCA |
4.712e-02 | -3.05 | IB | smart domains | SM00121 | 18 | 1 | 9717 | 26 |
IGFBP5 |
4.728e-02 | -3.05 | localization | biological process | GO:0051179 | 4474 | 18 | 18204 | 50 |
RELN,NDRG4,SCG5,CLU,DYNC1LI1,UQCR10,NDUFA1,SNCA,ATP6V0B,TXN,SYT1,ACHE,DNER,COX5B,NDUFB2,CD9,NDUFA5,CNTNAP2 |
4.760e-02 | -3.05 | cellular response to toxic substance | biological process | GO:0097237 | 127 | 2 | 18204 | 50 |
TXN,MGST3 |
4.767e-02 | -3.04 | RUN | prosite domains | PS50826 | 18 | 1 | 12186 | 33 |
RUFY3 |
4.767e-02 | -3.04 | FA58C_1 | prosite domains | PS01285 | 18 | 1 | 12186 | 33 |
CNTNAP2 |
4.767e-02 | -3.04 | BPTI_KUNITZ_2 | prosite domains | PS50279 | 18 | 1 | 12186 | 33 |
SPINT2 |
4.775e-02 | -3.04 | SYNAPTOTAGMN | prints domains | PR00399 | 17 | 1 | 5227 | 15 |
SYT1 |
4.792e-02 | -3.04 | APOO (apolipoprotein O) | protein interactions | 79135 | 139 | 2 | 19454 | 49 |
NDUFA5,COX5B |
4.792e-02 | -3.04 | DPPA4 (developmental pluripotency associated 4) | protein interactions | 55211 | 139 | 2 | 19454 | 49 |
TXN,CLU |
4.792e-02 | -3.04 | HSD17B13 (hydroxysteroid 17-beta dehydrogenase 13) | protein interactions | 345275 | 139 | 2 | 19454 | 49 |
THSD7A,IGFBP5 |
4.807e-02 | -3.04 | MAD2L2 (mitotic arrest deficient 2 like 2) | protein interactions | 10459 | 324 | 3 | 19454 | 49 |
SPINT2,NDUFA5,MLLT11 |
4.827e-02 | -3.03 | myelination | biological process | GO:0042552 | 128 | 2 | 18204 | 50 |
CLU,CD9 |
4.831e-02 | -3.03 | regulation of signaling | biological process | GO:0023051 | 3534 | 15 | 18204 | 50 |
DYNC1LI1,CLU,C1QTNF3,NDRG4,CHD5,SCG5,RELN,CALB2,PDE4B,TXN,SYT1,ACHE,IGFBP5,SNCA,SEZ6L2 |
4.832e-02 | -3.03 | cell migration involved in heart development | biological process | GO:0060973 | 18 | 1 | 18204 | 50 |
NDRG4 |
4.832e-02 | -3.03 | regulation of hydrogen peroxide metabolic process | biological process | GO:0010310 | 18 | 1 | 18204 | 50 |
SNCA |
4.832e-02 | -3.03 | spinal cord patterning | biological process | GO:0021511 | 18 | 1 | 18204 | 50 |
RELN |
4.832e-02 | -3.03 | positive regulation of dendritic spine morphogenesis | biological process | GO:0061003 | 18 | 1 | 18204 | 50 |
RELN |
4.832e-02 | -3.03 | negative regulation of platelet activation | biological process | GO:0010544 | 18 | 1 | 18204 | 50 |
CD9 |
4.832e-02 | -3.03 | response to misfolded protein | biological process | GO:0051788 | 18 | 1 | 18204 | 50 |
CLU |
4.832e-02 | -3.03 | regulation of protein kinase C signaling | biological process | GO:0090036 | 18 | 1 | 18204 | 50 |
SEZ6L2 |
4.832e-02 | -3.03 | type B pancreatic cell proliferation | biological process | GO:0044342 | 18 | 1 | 18204 | 50 |
IGFBP5 |
4.832e-02 | -3.03 | calcium ion-regulated exocytosis of neurotransmitter | biological process | GO:0048791 | 18 | 1 | 18204 | 50 |
SYT1 |
4.832e-02 | -3.03 | positive regulation of neuron migration | biological process | GO:2001224 | 18 | 1 | 18204 | 50 |
RELN |
4.832e-02 | -3.03 | myelin maintenance | biological process | GO:0043217 | 18 | 1 | 18204 | 50 |
CLU |
4.839e-02 | -3.03 | diencephalon | COSMIC cancer mutations | diencephalon | 17 | 1 | 16828 | 49 |
CNTNAP2 |
4.839e-02 | -3.03 | central_nervous_system-diencephalon-glioma-astrocytoma_Grade_I | COSMIC cancer mutations | central_nervous_system-diencephalon-glioma-astrocytoma_Grade_I | 17 | 1 | 16828 | 49 |
CNTNAP2 |
4.844e-02 | -3.03 | Kunitz_BPTI | pfam domains | PF00014 | 18 | 1 | 17795 | 49 |
SPINT2 |
4.844e-02 | -3.03 | RUN | pfam domains | PF02759 | 18 | 1 | 17795 | 49 |
RUFY3 |
4.848e-02 | -3.03 | Inflammasomes | REACTOME pathways | R-HSA-622312 | 17 | 1 | 10285 | 30 |
TXN |
4.848e-02 | -3.03 | Acetylcholine Neurotransmitter Release Cycle | REACTOME pathways | R-HSA-264642 | 17 | 1 | 10285 | 30 |
SYT1 |
4.853e-02 | -3.03 | STX3 (syntaxin 3) | protein interactions | 6809 | 140 | 2 | 19454 | 49 |
SYT1,MGST3 |
4.853e-02 | -3.03 | ARFGEF1 (ADP ribosylation factor guanine nucleotide exchange factor 1) | protein interactions | 10565 | 140 | 2 | 19454 | 49 |
SPINT2,NHLH2 |
4.853e-02 | -3.03 | CENPM (centromere protein M) | protein interactions | 79019 | 140 | 2 | 19454 | 49 |
GAP43,NRN1 |
4.853e-02 | -3.03 | DHCR24 (24-dehydrocholesterol reductase) | protein interactions | 1718 | 140 | 2 | 19454 | 49 |
RTN1,SNCA |
4.856e-02 | -3.02 | protein-folding chaperone binding | molecular function | GO:0051087 | 133 | 2 | 18094 | 48 |
SNCA,CLU |
4.859e-02 | -3.02 | parallel fiber to Purkinje cell synapse | cellular component | GO:0098688 | 19 | 1 | 19108 | 50 |
CALB2 |
4.859e-02 | -3.02 | gamma-tubulin complex | cellular component | GO:0000930 | 19 | 1 | 19108 | 50 |
PDE4B |
4.905e-02 | -3.01 | regulation of cell communication | biological process | GO:0010646 | 3541 | 15 | 18204 | 50 |
PDE4B,ACHE,SYT1,TXN,SEZ6L2,SNCA,IGFBP5,C1QTNF3,CLU,DYNC1LI1,CHD5,SCG5,NDRG4,CALB2,RELN |
4.911e-02 | -3.01 | PDEase | interpro domains | IPR023088 | 19 | 1 | 18521 | 49 |
PDE4B |
4.916e-02 | -3.01 | NDUFS5 (NADH:ubiquinone oxidoreductase subunit S5) | protein interactions | 4725 | 141 | 2 | 19454 | 49 |
NDUFA1,NDUFA5 |
4.916e-02 | -3.01 | CST1 (cystatin SN) | protein interactions | 1469 | 141 | 2 | 19454 | 49 |
SH3BGRL3,COX5B |
4.916e-02 | -3.01 | LIG4 (DNA ligase 4) | protein interactions | 3981 | 141 | 2 | 19454 | 49 |
CLU,TAGLN2 |
4.916e-02 | -3.01 | ZMPSTE24 (zinc metallopeptidase STE24) | protein interactions | 10269 | 141 | 2 | 19454 | 49 |
MGST3,DUSP23 |
4.921e-02 | -3.01 | SNCB (synuclein beta) | protein interactions | 6620 | 20 | 1 | 19454 | 49 |
SNCA |
4.921e-02 | -3.01 | LEP (leptin) | protein interactions | 3952 | 20 | 1 | 19454 | 49 |
CLU |
4.921e-02 | -3.01 | ITIH3 (inter-alpha-trypsin inhibitor heavy chain 3) | protein interactions | 3699 | 20 | 1 | 19454 | 49 |
SPINT2 |
4.921e-02 | -3.01 | CCKBR (cholecystokinin B receptor) | protein interactions | 887 | 20 | 1 | 19454 | 49 |
CCK |
4.921e-02 | -3.01 | HAND1 (heart and neural crest derivatives expressed 1) | protein interactions | 9421 | 20 | 1 | 19454 | 49 |
ACHE |
4.921e-02 | -3.01 | PON1 (paraoxonase 1) | protein interactions | 5444 | 20 | 1 | 19454 | 49 |
CLU |
4.921e-02 | -3.01 | JPH2 (junctophilin 2) | protein interactions | 57158 | 20 | 1 | 19454 | 49 |
EMX2 |
4.921e-02 | -3.01 | FAM228A (family with sequence similarity 228 member A) | protein interactions | 653140 | 20 | 1 | 19454 | 49 |
COX5B |
4.921e-02 | -3.01 | SLC25A21-AS1 (SLC25A21 antisense RNA 1) | protein interactions | 100129794 | 20 | 1 | 19454 | 49 |
DYNC1LI1 |
4.921e-02 | -3.01 | GJB3 (gap junction protein beta 3) | protein interactions | 2707 | 20 | 1 | 19454 | 49 |
IGFBP5 |
4.921e-02 | -3.01 | CDY2A (chromodomain Y-linked 2A) | protein interactions | 9426 | 20 | 1 | 19454 | 49 |
MLLT11 |
4.921e-02 | -3.01 | CTHRC1 (collagen triple helix repeat containing 1) | protein interactions | 115908 | 20 | 1 | 19454 | 49 |
C1QTNF3 |
4.921e-02 | -3.01 | CACFD1 (calcium channel flower domain containing 1) | protein interactions | 11094 | 20 | 1 | 19454 | 49 |
NDRG4 |
4.921e-02 | -3.01 | HDDC2 (HD domain containing 2) | protein interactions | 51020 | 20 | 1 | 19454 | 49 |
DUSP23 |
4.921e-02 | -3.01 | FXYD1 (FXYD domain containing ion transport regulator 1) | protein interactions | 5348 | 20 | 1 | 19454 | 49 |
NDRG4 |
4.921e-02 | -3.01 | ENC1 (ectodermal-neural cortex 1) | protein interactions | 8507 | 20 | 1 | 19454 | 49 |
SNCA |
4.921e-02 | -3.01 | KLF11 (KLF transcription factor 11) | protein interactions | 8462 | 20 | 1 | 19454 | 49 |
CLU |
4.921e-02 | -3.01 | DOK5 (docking protein 5) | protein interactions | 55816 | 20 | 1 | 19454 | 49 |
SCOC |
4.921e-02 | -3.01 | AQP10 (aquaporin 10) | protein interactions | 89872 | 20 | 1 | 19454 | 49 |
MGST3 |
4.924e-02 | -3.01 | syntaxin-1 binding | molecular function | GO:0017075 | 19 | 1 | 18094 | 48 |
SYT1 |
4.924e-02 | -3.01 | insulin-like growth factor binding | molecular function | GO:0005520 | 19 | 1 | 18094 | 48 |
IGFBP5 |
4.962e-02 | -3.00 | ensheathment of neurons | biological process | GO:0007272 | 130 | 2 | 18204 | 50 |
CD9,CLU |
4.962e-02 | -3.00 | axon ensheathment | biological process | GO:0008366 | 130 | 2 | 18204 | 50 |
CLU,CD9 |
4.999e-02 | -3.00 | regulation of biological quality | biological process | GO:0065008 | 2936 | 13 | 18204 | 50 |
GNG3,SNCA,ATP6V0B,SCOC,OLFM1,CD9,SCG5,MLLT11,RELN,CALB2,RUFY3,CLU,C1QTNF3 |