Gene Ontology Enrichment Results

Homer de novo Motif Enrichment Results
Known Motif Enrichment Results

Text file version of complete results (i.e. open with Excel)

Enriched Categories

P-valueln(P)TermGO TreeGO ID# of Genes in Term# of Target Genes in Term# of Total Genes# of Target GenesCommon Genes
1.275e-10-22.78PRNP (prion protein (Kanno blood group))protein interactions56211118181945450 LSAMP,SORBS1,PTPRZ1,MACF1,GPM6A,MSI2,CLU,SPARCL1,AQP4,TRPS1,NHSL1,SLC1A3,QKI,ABLIM1,APOE,CPE,MAML2,SLC4A4
7.292e-07-14.13soft_tissueCOSMIC cancer mutationssoft_tissue5828341682849 CLU,MAML2,PON2,APOE,COL5A3,FBXL7,PCDH9,NKAIN3,FGFR3,GLI3,NHSL1,CDH20,PAMR1,ARHGAP24,GPM6A,SORBS1,PREX2,NFIA,TRPS1,PARD3B,MACF1,GLIS3,SPON1,SLC1A3,PTPRZ1,AQP4,MEIS2,NPAS3,RYR3,CTNND2,SLC1A2,LSAMP,GPC5,SPARCL1
1.343e-06-13.52blood_vesselCOSMIC cancer mutationsblood_vessel2211201682849 MEIS2,ARHGAP24,CDH20,LSAMP,PREX2,GPM6A,RYR3,SLC1A2,CTNND2,GPC5,MAML2,COL5A3,FBXL7,FGFR3,GLI3,PTPRZ1,SPON1,PCDH9,SLC1A3,NKAIN3
1.475e-06-13.43cerebellumCOSMIC cancer mutationscerebellum769121682849 CPE,QKI,NPAS3,MEIS2,CTNND2,RYR3,GPC5,PARD3B,ABLIM1,MAML2,PCDH9,PTPRZ1
1.565e-06-13.37nervous system developmentbiological processGO:00073992185191820449 PTPRZ1,SLC1A3,LSAMP,CTNND2,APOE,CLU,MSI2,PCDH9,GLI3,CTNNA2,MEIS2,GPM6A,NFIA,NDRG2,QKI,PREX2,NTM,SLC1A2,BMPR1B
1.606e-06-13.34cell morphogenesisbiological processGO:0000902687111820449 NFIA,PREX2,BMPR1B,GLI3,GPM6A,CTNNA2,CLU,CDH20,PTPRZ1,CTNND2,SLC1A3
1.845e-06-13.20prostate-carcinomaCOSMIC cancer mutationsprostate-carcinoma9000421682849 SPARCL1,GPC5,LSAMP,CTNND2,SLC1A2,RYR3,NTM,NPAS3,MEIS2,SLC4A4,ATP13A4,QKI,CPE,PTPRZ1,SLC1A3,SPON1,GLIS3,BMPR1B,PITPNC1,MACF1,PARD3B,TRPS1,NFIA,PREX2,SORBS1,GPM6A,ARHGAP24,MSI2,CDH20,NHSL1,GLI3,FGFR3,NKAIN3,PCDH9,FBXL7,COL5A3,APOE,PON2,MAML2,DTNA,ABLIM1,CLU
3.226e-06-12.64Burkitt_lymphomaCOSMIC cancer mutationsBurkitt_lymphoma2119191682849 MAML2,GLI3,NKAIN3,SLC1A3,PCDH9,SPON1,FBXL7,BMPR1B,NHSL1,NPAS3,ATP13A4,CPE,GPC5,LSAMP,PREX2,SLC1A2,CTNND2,GPM6A,RYR3
3.226e-06-12.64haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-Burkitt_lymphomaCOSMIC cancer mutationshaematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-Burkitt_lymphoma2119191682849 BMPR1B,FBXL7,PCDH9,SPON1,NKAIN3,SLC1A3,GLI3,MAML2,RYR3,GPM6A,CTNND2,SLC1A2,PREX2,LSAMP,GPC5,ATP13A4,CPE,NPAS3,NHSL1
3.494e-06-12.56acute_myeloid_leukaemia_therapy_relatedCOSMIC cancer mutationsacute_myeloid_leukaemia_therapy_related1523161682849 GLI3,PCDH9,SPON1,NKAIN3,SLC1A3,COL5A3,ACSS1,FBXL7,MAML2,GPC5,LSAMP,PREX2,RYR3,CTNND2,MEIS2,QKI
3.494e-06-12.56haematopoietic_and_lymphoid_tissue-haematopoietic_neoplasm-acute_myeloid_leukaemia_therapy_relatedCOSMIC cancer mutationshaematopoietic_and_lymphoid_tissue-haematopoietic_neoplasm-acute_myeloid_leukaemia_therapy_related1523161682849 MEIS2,QKI,GPC5,LSAMP,PREX2,RYR3,CTNND2,MAML2,GLI3,PCDH9,SPON1,SLC1A3,NKAIN3,COL5A3,ACSS1,FBXL7
3.516e-06-12.56tibiaCOSMIC cancer mutationstibia836121682849 LSAMP,PREX2,GPM6A,CTNND2,QKI,CPE,FGFR3,NDRG2,NKAIN3,ACSS1,MACF1,ABLIM1
3.650e-06-12.52MAPT (microtubule associated protein tau)protein interactions4137948121945450 LSAMP,NTM,SORBS1,GPM6A,SLC1A2,CTNND2,CLU,SLC1A3,APOE,ABLIM1,CTNNA2,NDRG2
4.655e-06-12.28cell peripherycellular componentGO:00719446020311910849 ATP13A4,CTNNA2,GPC5,AQP4,PARD3B,SPARCL1,NKAIN3,CDH20,RYR3,PTPRZ1,CTNND2,DTNA,MACF1,LSAMP,GPM6A,FGFR3,SLC4A4,BMPR1B,PCDH9,CLU,CST3,PON2,APOE,PREX2,SLC1A3,SLC1A2,SPON1,NTM,COL5A3,SORBS1,CPE
4.679e-06-12.27cell junctioncellular componentGO:00300542224181910849 CDH20,SLC1A3,PTPRZ1,SLC1A2,CTNND2,DTNA,NFIA,GPM6A,FGFR3,SORBS1,PCDH9,CLU,CTNNA2,QKI,APOE,ARHGAP24,SPARCL1,PARD3B
4.871e-06-12.23diffuse_large_B_cell_lymphomaCOSMIC cancer mutationsdiffuse_large_B_cell_lymphoma4151271682849 SPON1,SLC1A3,MACF1,RYR3,SLC1A2,CTNND2,LSAMP,GPC5,SPARCL1,CPE,ATP13A4,AQP4,QKI,MEIS2,ACSS1,FBXL7,PCDH9,NKAIN3,GLI3,FGFR3,CLU,DTNA,MAML2,GPM6A,PREX2,TRPS1,CDH20
5.357e-06-12.14angiosarcomaCOSMIC cancer mutationsangiosarcoma2192191682849 CDH20,ARHGAP24,MEIS2,GPC5,RYR3,GPM6A,CTNND2,SLC1A2,PREX2,LSAMP,MAML2,PCDH9,SPON1,SLC1A3,NKAIN3,GLI3,PTPRZ1,COL5A3,FBXL7
5.357e-06-12.14soft_tissue-blood_vessel-angiosarcomaCOSMIC cancer mutationssoft_tissue-blood_vessel-angiosarcoma2192191682849 GLI3,PTPRZ1,PCDH9,SPON1,SLC1A3,NKAIN3,COL5A3,FBXL7,MAML2,GPC5,LSAMP,PREX2,RYR3,GPM6A,SLC1A2,CTNND2,ARHGAP24,CDH20,MEIS2
7.388e-06-11.82pharynxCOSMIC cancer mutationspharynx2696211682849 NHSL1,NPAS3,ATP13A4,QKI,SLC4A4,PARD3B,NFIA,GPC5,PREX2,RYR3,SLC1A2,CTNND2,SORBS1,PITPNC1,MACF1,CLU,DTNA,FGFR3,PTPRZ1,PCDH9,AMZ2
8.073e-06-11.73haematopoietic_and_lymphoid_tissue-lymph_node-lymphoid_neoplasm-mantle_cell_lymphomaCOSMIC cancer mutationshaematopoietic_and_lymphoid_tissue-lymph_node-lymphoid_neoplasm-mantle_cell_lymphoma47691682849 ATP13A4,MAML2,MEIS2,RYR3,GPM6A,CTNND2,LSAMP,GPC5,PCDH9
8.240e-06-11.71adherens junctioncellular componentGO:000591218861910849 CTNND2,SORBS1,CTNNA2,ARHGAP24,PARD3B,CDH20
9.341e-06-11.58anatomical structure morphogenesisbiological processGO:00096532225181820449 BMPR1B,QKI,FGFR3,NFIA,PREX2,CTNNA2,ABLIM1,MEIS2,GPM6A,GLI3,CLU,ARHGAP24,SLC1A3,CTNND2,APOE,PTPRZ1,CPE,CDH20
1.097e-05-11.42chronic_lymphocytic_leukaemia-small_lymphocytic_lymphomaCOSMIC cancer mutationschronic_lymphocytic_leukaemia-small_lymphocytic_lymphoma3511241682849 GPC5,RYR3,CTNND2,LSAMP,CPE,SLC4A4,NPAS3,MEIS2,SPON1,SLC1A3,PTPRZ1,BMPR1B,PITPNC1,MACF1,PARD3B,PREX2,MSI2,PAMR1,PCDH9,AMZ2,GLI3,FBXL7,CLU,DTNA
1.097e-05-11.42haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-chronic_lymphocytic_leukaemia-small_lymphocytic_lymphomaCOSMIC cancer mutationshaematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-chronic_lymphocytic_leukaemia-small_lymphocytic_lymphoma3511241682849 GLI3,PCDH9,AMZ2,FBXL7,CLU,DTNA,PARD3B,PREX2,PAMR1,MSI2,PTPRZ1,SPON1,SLC1A3,BMPR1B,PITPNC1,MACF1,GPC5,LSAMP,RYR3,CTNND2,NPAS3,MEIS2,CPE,SLC4A4
1.167e-05-11.36system developmentbiological processGO:00487313533231820449 CTNNA2,GPM6A,MEIS2,PCDH9,GLI3,NTM,BMPR1B,SLC1A2,PREX2,FGFR3,NDRG2,NFIA,QKI,LSAMP,SLC1A3,APOE,TRPS1,CTNND2,CPE,PTPRZ1,CLU,MSI2,ARHGAP24
1.310e-05-11.24central_nervous_system-brain-primitive_neuroectodermal_tumour-medulloblastomaCOSMIC cancer mutationscentral_nervous_system-brain-primitive_neuroectodermal_tumour-medulloblastoma7205361682849 NHSL1,PAMR1,GPM6A,SORBS1,PREX2,NFIA,TRPS1,PARD3B,ABLIM1,MAML2,PON2,COL5A3,ACSS1,FBXL7,PCDH9,NKAIN3,GLI3,FGFR3,CPE,ATP13A4,QKI,SLC4A4,NPAS3,MEIS2,NTM,RYR3,CTNND2,SLC1A2,LSAMP,GPC5,MACF1,PITPNC1,GLIS3,SPON1,SLC1A3,PTPRZ1
1.425e-05-11.16haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-acute_lymphoblastic_B_cell_leukaemiaCOSMIC cancer mutationshaematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-acute_lymphoblastic_B_cell_leukaemia3828251682849 GLIS3,BMPR1B,PTPRZ1,SPON1,SLC1A3,MEIS2,CPE,ATP13A4,SLC4A4,NTM,LSAMP,RYR3,CTNND2,SLC1A2,GPC5,MAML2,COL5A3,FBXL7,GLI3,PCDH9,NKAIN3,PAMR1,PREX2,GPM6A,NFIA
1.425e-05-11.16acute_lymphoblastic_B_cell_leukaemiaCOSMIC cancer mutationsacute_lymphoblastic_B_cell_leukaemia3828251682849 MAML2,COL5A3,FBXL7,PCDH9,NKAIN3,GLI3,PAMR1,GPM6A,PREX2,NFIA,BMPR1B,GLIS3,SPON1,SLC1A3,PTPRZ1,CPE,ATP13A4,SLC4A4,MEIS2,NTM,RYR3,SLC1A2,CTNND2,LSAMP,GPC5
1.468e-05-11.13lymph_nodeCOSMIC cancer mutationslymph_node1703161682849 TRPS1,GPC5,PARD3B,CTNND2,GPM6A,RYR3,LSAMP,ARHGAP24,ATP13A4,MEIS2,SLC1A3,PCDH9,FGFR3,ACSS1,DTNA,MAML2
1.509e-05-11.10central_nervous_system-cerebellum-primitive_neuroectodermal_tumour-medulloblastoma-SHH_subtypeCOSMIC cancer mutationscentral_nervous_system-cerebellum-primitive_neuroectodermal_tumour-medulloblastoma-SHH_subtype653101682849 MAML2,NPAS3,MEIS2,ABLIM1,CPE,CTNND2,RYR3,PTPRZ1,PARD3B,PCDH9
1.529e-05-11.09SHH_subtypeCOSMIC cancer mutationsSHH_subtype654101682849 RYR3,CTNND2,PCDH9,PARD3B,PTPRZ1,CPE,ABLIM1,MAML2,NPAS3,MEIS2
1.782e-05-10.94haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-diffuse_large_B_cell_lymphomaCOSMIC cancer mutationshaematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-diffuse_large_B_cell_lymphoma3608241682849 MAML2,CLU,FGFR3,GLI3,NKAIN3,PCDH9,ACSS1,FBXL7,CDH20,PREX2,GPM6A,MACF1,SPON1,MEIS2,ATP13A4,AQP4,QKI,CPE,SPARCL1,GPC5,LSAMP,CTNND2,SLC1A2,RYR3
1.847e-05-10.90brainstemCOSMIC cancer mutationsbrainstem3102221682849 CDH20,PREX2,GPM6A,MAML2,FBXL7,FGFR3,GLI3,NKAIN3,PCDH9,MEIS2,NPAS3,QKI,ATP13A4,CPE,LSAMP,CTNND2,SLC1A2,RYR3,GPC5,PTPRZ1,SLC1A3,SPON1
2.276e-05-10.69multicellular organism developmentbiological processGO:00072753957241820449 CTNNA2,GPM6A,GLI3,SLC1A2,NDRG2,QKI,PREX2,SLC1A3,TRPS1,CPE,CDH20,CLU,MSI2,MEIS2,PCDH9,NTM,BMPR1B,FGFR3,NFIA,LSAMP,CTNND2,APOE,PTPRZ1,ARHGAP24
3.199e-05-10.35cell adhesionbiological processGO:0007155942111820449 COL5A3,NTM,SPON1,PCDH9,CDH20,CTNNA2,LSAMP,SPARCL1,CTNND2,SORBS1,PARD3B
3.599e-05-10.23neurogenesisbiological processGO:00220081334131820449 GLI3,CTNNA2,GPM6A,QKI,NFIA,PREX2,NTM,BMPR1B,PTPRZ1,SLC1A3,CTNND2,APOE,CLU
4.330e-05-10.05central_nervous_system-brainstem-glioma-astrocytoma_Grade_IVCOSMIC cancer mutationscentral_nervous_system-brainstem-glioma-astrocytoma_Grade_IV2531191682849 FBXL7,SPON1,PCDH9,SLC1A3,NKAIN3,GLI3,PTPRZ1,MAML2,GPM6A,RYR3,CTNND2,LSAMP,PREX2,GPC5,ATP13A4,CPE,QKI,MEIS2,CDH20
4.917e-05-9.92Neurotransmitter uptake and Metabolism In Glial CellsREACTOME pathwaysR-HSA-112313421028530 SLC1A3,SLC1A2
4.917e-05-9.92Astrocytic Glutamate-Glutamine Uptake And MetabolismREACTOME pathwaysR-HSA-210455421028530 SLC1A2,SLC1A3
5.275e-05-9.85central nervous system developmentbiological processGO:0007417995111820449 CLU,NDRG2,QKI,MSI2,BMPR1B,SLC1A2,PTPRZ1,PCDH9,GLI3,CTNNA2,MEIS2
5.762e-05-9.76haematopoietic_and_lymphoid_tissue-haematopoietic_neoplasmCOSMIC cancer mutationshaematopoietic_and_lymphoid_tissue-haematopoietic_neoplasm764101682849 MAML2,NKAIN3,GPC5,PCDH9,SLC1A2,RYR3,FBXL7,LSAMP,COL5A3,PREX2
6.151e-05-9.70rhabdomyosarcomaCOSMIC cancer mutationsrhabdomyosarcoma4150251682849 NPAS3,AQP4,RYR3,CTNND2,SPARCL1,MACF1,GLIS3,PTPRZ1,SPON1,SLC1A3,NHSL1,PAMR1,CDH20,PREX2,SORBS1,PARD3B,NFIA,TRPS1,MAML2,PON2,CLU,APOE,COL5A3,GLI3,FGFR3
6.375e-05-9.66negative regulation of amyloid-beta formationbiological processGO:19024302931820449 SPON1,CLU,APOE
6.535e-05-9.64mantle_cell_lymphomaCOSMIC cancer mutationsmantle_cell_lymphoma2849201682849 SLC1A2,CTNND2,GPM6A,RYR3,LSAMP,PREX2,TRPS1,GPC5,PARD3B,ATP13A4,CPE,MEIS2,ARHGAP24,FBXL7,SLC1A3,NKAIN3,SPON1,PCDH9,GLI3,MAML2
6.856e-05-9.59high-affinity L-glutamate transmembrane transporter activitymolecular functionGO:0005314521809448 SLC1A3,SLC1A2
6.856e-05-9.59glutamate:sodium symporter activitymolecular functionGO:0015501521809448 SLC1A2,SLC1A3
7.061e-05-9.56D-aspartate transmembrane transportbiological processGO:0070777521820449 SLC1A3,SLC1A2
7.061e-05-9.56positive regulation of amyloid fibril formationbiological processGO:1905908521820449 CLU,APOE
7.061e-05-9.56D-aspartate import across plasma membranebiological processGO:0070779521820449 SLC1A3,SLC1A2
7.813e-05-9.46negative regulation of amyloid precursor protein catabolic processbiological processGO:19029923131820449 APOE,CLU,SPON1
7.981e-05-9.44neuron developmentbiological processGO:0048666859101820449 GLI3,PTPRZ1,CTNND2,GPM6A,APOE,SLC1A3,CTNNA2,PREX2,BMPR1B,NTM
8.255e-05-9.40NTM (neurotrimin)protein interactions508633331945450 NTM,GPM6A,LSAMP
8.334e-05-9.39soft_tissue-striated_muscle-rhabdomyosarcoma-alveolarCOSMIC cancer mutationssoft_tissue-striated_muscle-rhabdomyosarcoma-alveolar2414181682849 NPAS3,NHSL1,PAMR1,CDH20,PREX2,RYR3,SORBS1,PARD3B,NFIA,TRPS1,SPARCL1,MACF1,PON2,CLU,APOE,FGFR3,SPON1,SLC1A3
8.334e-05-9.39alveolarCOSMIC cancer mutationsalveolar2414181682849 NHSL1,PAMR1,CDH20,NPAS3,NFIA,TRPS1,SPARCL1,PARD3B,RYR3,SORBS1,PREX2,APOE,CLU,MACF1,PON2,SPON1,SLC1A3,FGFR3
8.349e-05-9.39multicellular organismal processbiological processGO:00325016177301820449 ARHGAP24,LSAMP,PTGDS,APOE,CTNND2,PTPRZ1,NTM,BMPR1B,SLC4A4,FGFR3,NFIA,ABLIM1,MEIS2,DTNA,PCDH9,CLU,MSI2,SLC1A3,TRPS1,CPE,CDH20,SLC1A2,PREX2,AQP4,QKI,NDRG2,CTNNA2,GPM6A,RYR3,GLI3
8.544e-05-9.37striated_muscleCOSMIC cancer mutationsstriated_muscle4228251682849 SORBS1,PREX2,NFIA,TRPS1,PARD3B,NHSL1,CDH20,PAMR1,COL5A3,FGFR3,GLI3,CLU,MAML2,PON2,APOE,RYR3,CTNND2,SPARCL1,AQP4,NPAS3,GLIS3,SPON1,SLC1A3,PTPRZ1,MACF1
8.642e-05-9.36embryonalCOSMIC cancer mutationsembryonal2659191682849 PARD3B,NFIA,SPARCL1,PREX2,RYR3,SORBS1,CTNND2,NPAS3,AQP4,FGFR3,GLI3,PTPRZ1,SPON1,COL5A3,GLIS3,APOE,MACF1,MAML2,PON2
8.642e-05-9.36soft_tissue-striated_muscle-rhabdomyosarcoma-embryonalCOSMIC cancer mutationssoft_tissue-striated_muscle-rhabdomyosarcoma-embryonal2659191682849 APOE,PON2,MAML2,MACF1,PTPRZ1,GLI3,FGFR3,SPON1,GLIS3,COL5A3,NPAS3,AQP4,PARD3B,SPARCL1,NFIA,PREX2,CTNND2,SORBS1,RYR3
8.887e-05-9.33anatomical structure developmentbiological processGO:00488565207271820449 SLC1A3,TRPS1,CPE,CDH20,CLU,MSI2,CTNNA2,SPARCL1,GPM6A,GLI3,SLC1A2,NDRG2,QKI,PREX2,LSAMP,CTNND2,APOE,PTPRZ1,COL5A3,ARHGAP24,ABLIM1,MEIS2,PCDH9,NTM,BMPR1B,FGFR3,NFIA
1.027e-04-9.18collagen-containing extracellular matrixcellular componentGO:006202342871910849 CLU,APOE,PTPRZ1,SPON1,SPARCL1,COL5A3,GPC5
1.034e-04-9.18negative regulation of amide metabolic processbiological processGO:00342493431820449 APOE,CLU,SPON1
1.057e-04-9.15L-aspartate import across plasma membranebiological processGO:0140009621820449 SLC1A2,SLC1A3
1.057e-04-9.15D-amino acid transportbiological processGO:0042940621820449 SLC1A2,SLC1A3
1.064e-04-9.15GLI-likeinterpro domainsIPR043359621852150 GLIS3,GLI3
1.080e-04-9.13autonomic_gangliaCOSMIC cancer mutationsautonomic_ganglia4005241682849 NHSL1,NFIA,TRPS1,PARD3B,GPM6A,PREX2,MAML2,PCDH9,AMZ2,GLI3,FGFR3,COL5A3,FBXL7,ACSS1,AQP4,SLC4A4,NPAS3,RYR3,CTNND2,SLC1A2,PITPNC1,MACF1,PTPRZ1,GLIS3
1.112e-04-9.10neuron differentiationbiological processGO:00301821081111820449 GPM6A,CTNNA2,GLI3,BMPR1B,NTM,PREX2,NFIA,APOE,CTNND2,SLC1A3,PTPRZ1
1.139e-04-9.08plasma membranecellular componentGO:00058865538271910849 PARD3B,AQP4,CTNNA2,ATP13A4,GPC5,BMPR1B,LSAMP,FGFR3,SLC4A4,GPM6A,MACF1,CTNND2,DTNA,RYR3,NKAIN3,CDH20,PTPRZ1,PREX2,APOE,CST3,PCDH9,PON2,SORBS1,CPE,NTM,SLC1A2,SLC1A3
1.287e-04-8.96haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-mantle_cell_lymphomaCOSMIC cancer mutationshaematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-mantle_cell_lymphoma2737191682849 PCDH9,SPON1,NKAIN3,SLC1A3,GLI3,FBXL7,MAML2,GPC5,TRPS1,PARD3B,GPM6A,RYR3,SLC1A2,CTNND2,LSAMP,PREX2,ARHGAP24,CPE,MEIS2
1.399e-04-8.87endoplasmic reticulum lumencellular componentGO:000578831261910849 COL5A3,SPON1,SPARCL1,APOE,CLU,CST3
1.462e-04-8.83ductolobular_carcinomaCOSMIC cancer mutationsductolobular_carcinoma1619141682849 MACF1,ABLIM1,DTNA,FGFR3,GLI3,NDRG2,PTPRZ1,CDH20,CPE,QKI,PARD3B,PREX2,CTNND2,SORBS1
1.462e-04-8.83breast-carcinoma-ductolobular_carcinomaCOSMIC cancer mutationsbreast-carcinoma-ductolobular_carcinoma1619141682849 PARD3B,PREX2,CTNND2,SORBS1,CDH20,CPE,QKI,GLI3,FGFR3,NDRG2,PTPRZ1,MACF1,ABLIM1,DTNA
1.469e-04-8.83HUNK (hormonally up-regulated Neu-associated kinase)protein interactions3081110441945450 SORBS1,SPARCL1,CLU,ABLIM1
1.487e-04-8.81Na:dicarbo_symporter_sfinterpro domainsIPR036458721852150 SLC1A3,SLC1A2
1.487e-04-8.81Na-dicarboxylate_symporterinterpro domainsIPR001991721852150 SLC1A2,SLC1A3
1.487e-04-8.81Na-dicarboxylate_symporter_CSinterpro domainsIPR018107721852150 SLC1A3,SLC1A2
1.565e-04-8.76cellular response to alkaloidbiological processGO:00713123931820449 RYR3,SLC1A2,SLC1A3
1.610e-04-8.73SDFpfam domainsPF00375721779550 SLC1A3,SLC1A2
1.687e-04-8.69developmental processbiological processGO:00325025716281820449 SLC1A3,TRPS1,CPE,CDH20,CLU,MSI2,CTNNA2,SPARCL1,GPM6A,GLI3,SLC1A2,QKI,NDRG2,PREX2,LSAMP,CTNND2,APOE,PTPRZ1,COL5A3,ARHGAP24,ABLIM1,NHSL1,MEIS2,PCDH9,NTM,BMPR1B,FGFR3,NFIA
1.712e-04-8.67cell morphogenesis involved in neuron differentiationbiological processGO:004866744371820449 PREX2,BMPR1B,PTPRZ1,GLI3,CTNNA2,SLC1A3,CTNND2
1.776e-04-8.64CTNNA1 (catenin alpha 1)protein interactions149532561945450 DTNA,ABLIM1,MACF1,CTNNA2,SORBS1,NHSL1
1.841e-04-8.60beta-catenin bindingmolecular functionGO:000801310741809448 CDH20,CTNND2,CTNNA2,GLI3
1.874e-04-8.58bone-tibia-other-chondroblastomaCOSMIC cancer mutationsbone-tibia-other-chondroblastoma9841682849 NKAIN3,CTNND2,GPM6A,LSAMP
1.879e-04-8.58Sodium:dicarboxylate symportergene3d domains1.10.3860.10721447044 SLC1A2,SLC1A3
1.967e-04-8.53protein importbiological processGO:0017038821820449 CLU,APOE
2.035e-04-8.50cell projectioncellular componentGO:00429952398161910849 ARHGAP24,APOE,AQP4,NDRG2,CTNNA2,ABLIM1,PCDH9,CLU,BMPR1B,GPM6A,MACF1,DTNA,CTNND2,SLC1A2,GLI3,SLC1A3
2.040e-04-8.50generation of neuronsbiological processGO:00486991158111820449 GPM6A,CTNNA2,GLI3,BMPR1B,NTM,PREX2,NFIA,APOE,CTNND2,SLC1A3,PTPRZ1
2.304e-04-8.38KLB (klotho beta)protein interactions152831921945450 FGFR3,ARHGAP24
2.304e-04-8.38LSAMP (limbic system associated membrane protein)protein interactions4045921945450 NTM,LSAMP
2.304e-04-8.38NEGR1 (neuronal growth regulator 1)protein interactions257194921945450 LSAMP,NTM
2.409e-04-8.33NA_DICARBOXYL_SYMP_1prosite domainsPS00713721218642 SLC1A2,SLC1A3
2.409e-04-8.33NA_DICARBOXYL_SYMP_2prosite domainsPS00714721218642 SLC1A2,SLC1A3
2.888e-04-8.15EDTRNSPORTprints domainsPR0017372522720 SLC1A2,SLC1A3
2.894e-04-8.15autonomic_ganglia-neuroblastomaCOSMIC cancer mutationsautonomic_ganglia-neuroblastoma3970231682849 NPAS3,SLC4A4,AQP4,PARD3B,TRPS1,NFIA,PREX2,SLC1A2,CTNND2,GPM6A,RYR3,PITPNC1,MACF1,MAML2,PTPRZ1,GLI3,FGFR3,AMZ2,PCDH9,ACSS1,GLIS3,FBXL7,COL5A3
2.905e-04-8.14neuroblastomaCOSMIC cancer mutationsneuroblastoma3971231682849 MAML2,COL5A3,ACSS1,FBXL7,FGFR3,GLI3,PCDH9,AMZ2,PREX2,GPM6A,PARD3B,NFIA,TRPS1,MACF1,PITPNC1,GLIS3,PTPRZ1,NPAS3,AQP4,SLC4A4,RYR3,SLC1A2,CTNND2
2.909e-04-8.14nodularCOSMIC cancer mutationsnodular1515131682849 SPARCL1,PREX2,CTNND2,CDH20,NPAS3,SLC4A4,ATP13A4,CPE,PTPRZ1,FGFR3,GLIS3,MACF1,ABLIM1
2.911e-04-8.14regulation of amyloid-beta formationbiological processGO:19020034831820449 APOE,CLU,SPON1
2.984e-04-8.12glial cell differentiationbiological processGO:001000121951820449 CLU,QKI,NFIA,PTPRZ1,GLI3
3.013e-04-8.11neuron projection morphogenesisbiological processGO:004881248671820449 GPM6A,CTNND2,CTNNA2,GLI3,PTPRZ1,BMPR1B,PREX2
3.121e-04-8.07cell-cell junctioncellular componentGO:000591151371910849 PCDH9,CDH20,CTNNA2,CTNND2,PARD3B,ARHGAP24,SORBS1
3.150e-04-8.06cellular response to cocainebiological processGO:00713141021820449 SLC1A3,SLC1A2
3.162e-04-8.06PAX9 (paired box 9)protein interactions508312741945450 QKI,TRPS1,NFIA,ARHGAP24
3.205e-04-8.05plasma membrane bounded cell projection morphogenesisbiological processGO:012003949171820449 PTPRZ1,PREX2,GLI3,CTNNA2,CTNND2,GPM6A,BMPR1B
3.234e-04-8.04upper_aerodigestive_tract-mouth-carcinomaCOSMIC cancer mutationsupper_aerodigestive_tract-mouth-carcinoma6426311682849 FGFR3,GLI3,AMZ2,FBXL7,ACSS1,COL5A3,APOE,MAML2,CLU,ABLIM1,PARD3B,TRPS1,PREX2,SORBS1,GPM6A,CDH20,PAMR1,NHSL1,NDRG2,SLC1A3,SPON1,PITPNC1,MACF1,GPC5,CTNND2,SLC1A2,RYR3,NTM,NPAS3,SLC4A4,QKI
3.407e-04-7.98cell projection morphogenesisbiological processGO:004885849671820449 BMPR1B,PREX2,GPM6A,CTNND2,CTNNA2,GLI3,PTPRZ1
3.844e-04-7.86L-glutamate import across plasma membranebiological processGO:00987121121820449 SLC1A3,SLC1A2
3.844e-04-7.86L-aspartate transmembrane transportbiological processGO:00707781121820449 SLC1A3,SLC1A2
3.906e-04-7.85regulation of chondrocyte differentiationbiological processGO:00323305331820449 BMPR1B,TRPS1,GLI3
4.023e-04-7.82CSTL1 (cystatin like 1)protein interactions1288175631945450 CLU,APOE,CPE
4.129e-04-7.79plasma membrane bounded cell projectioncellular componentGO:01200252285151910849 APOE,AQP4,NDRG2,CTNNA2,CLU,PCDH9,ABLIM1,BMPR1B,GPM6A,DTNA,CTNND2,MACF1,SLC1A2,GLI3,SLC1A3
4.203e-04-7.77TREM2 (triggering receptor expressed on myeloid cells 2)protein interactions542091221945450 CLU,APOE
4.357e-04-7.74regulation of amyloid precursor protein catabolic processbiological processGO:19029915531820449 APOE,SPON1,CLU
4.466e-04-7.71neuron projectioncellular componentGO:00430051331111910849 APOE,PCDH9,CLU,NDRG2,CTNNA2,GPM6A,BMPR1B,SLC1A3,DTNA,CTNND2,SLC1A2
4.513e-04-7.70haematopoietic_and_lymphoid_tissue-haematopoietic_neoplasm-myelodysplastic_syndromeCOSMIC cancer mutationshaematopoietic_and_lymphoid_tissue-haematopoietic_neoplasm-myelodysplastic_syndrome1174111682849 FGFR3,NKAIN3,NFIA,FBXL7,LSAMP,PREX2,COL5A3,SLC1A2,BMPR1B,RYR3,NPAS3
4.513e-04-7.70myelodysplastic_syndromeCOSMIC cancer mutationsmyelodysplastic_syndrome1174111682849 RYR3,SLC1A2,LSAMP,PREX2,NFIA,NPAS3,BMPR1B,COL5A3,FBXL7,NKAIN3,FGFR3
4.796e-04-7.64neuron projection developmentbiological processGO:003117569381820449 PREX2,BMPR1B,GLI3,PTPRZ1,CTNND2,APOE,GPM6A,CTNNA2
5.187e-04-7.56cell junction organizationbiological processGO:003433053271820449 SPARCL1,APOE,GPM6A,SORBS1,CTNND2,CDH20,NFIA
5.199e-04-7.56CTNNB1 (catenin beta 1)protein interactions149992691945450 NHSL1,SORBS1,PTPRZ1,CTNND2,CTNNA2,PARD3B,ARHGAP24,DTNA,APOE
5.225e-04-7.56extracellular matrixcellular componentGO:003101255971910849 SPARCL1,SPON1,GPC5,COL5A3,CLU,PTPRZ1,APOE
5.281e-04-7.55external encapsulating structurecellular componentGO:003031256071910849 APOE,PTPRZ1,CLU,COL5A3,GPC5,SPON1,SPARCL1
5.432e-04-7.52negative regulation of amyloid fibril formationbiological processGO:19059071321820449 APOE,CLU
5.776e-04-7.46C9 (complement C9)protein interactions7351421945450 CLU,APOE
5.776e-04-7.46PLXNA4 (plexin A4)protein interactions915841421945450 GPM6A,CLU
5.776e-04-7.46CTSO (cathepsin O)protein interactions15191421945450 CST3,AMZ2
6.145e-04-7.39L-glutamate transmembrane transporter activitymolecular functionGO:00053131421809448 SLC1A3,SLC1A2
6.239e-04-7.38upper_aerodigestive_tract-pharynx-carcinoma-nasopharyngeal_carcinomaCOSMIC cancer mutationsupper_aerodigestive_tract-pharynx-carcinoma-nasopharyngeal_carcinoma1425121682849 SLC4A4,CLU,QKI,ATP13A4,PITPNC1,NHSL1,SLC1A2,CTNND2,PREX2,AMZ2,NFIA,FGFR3
6.239e-04-7.38nasopharyngeal_carcinomaCOSMIC cancer mutationsnasopharyngeal_carcinoma1425121682849 FGFR3,NFIA,AMZ2,PREX2,SLC1A2,CTNND2,NHSL1,PITPNC1,ATP13A4,CLU,QKI,SLC4A4
6.654e-04-7.32RNASE13 (ribonuclease A family member 13 (inactive))protein interactions4401631521945450 CLU,CPE
6.803e-04-7.29dendrite morphogenesisbiological processGO:00488136431820449 CTNND2,CTNNA2,PREX2
7.592e-04-7.18CNTNAP2 (contactin associated protein 2)protein interactions260471621945450 CPE,MACF1
8.133e-04-7.11carcinoid-endocrine_tumourCOSMIC cancer mutationscarcinoid-endocrine_tumour7752341682849 COL5A3,ACSS1,FBXL7,PCDH9,NKAIN3,FGFR3,GLI3,CLU,ABLIM1,MAML2,PON2,APOE,GPM6A,PREX2,TRPS1,NHSL1,CDH20,PAMR1,BMPR1B,GLIS3,SPON1,SLC1A3,PTPRZ1,MACF1,RYR3,CTNND2,SLC1A2,LSAMP,GPC5,ATP13A4,QKI,CPE,SLC4A4,MEIS2
8.340e-04-7.09plasma_cell_myelomaCOSMIC cancer mutationsplasma_cell_myeloma1263111682849 MACF1,ATP13A4,ABLIM1,NTM,PAMR1,GPM6A,RYR3,CTNND2,GLI3,FGFR3,TRPS1
8.340e-04-7.09haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-plasma_cell_myelomaCOSMIC cancer mutationshaematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-plasma_cell_myeloma1263111682849 MACF1,ABLIM1,ATP13A4,NTM,PAMR1,CTNND2,GPM6A,RYR3,FGFR3,GLI3,TRPS1
8.403e-04-7.08gliogenesisbiological processGO:004206327551820449 CLU,PTPRZ1,NFIA,QKI,GLI3
8.422e-04-7.08chondroblastomaCOSMIC cancer mutationschondroblastoma53471682849 RYR3,GPM6A,CTNND2,LSAMP,GPC5,PCDH9,NKAIN3
8.516e-04-7.07spindleCOSMIC cancer mutationsspindle38661682849 PREX2,MACF1,CTNND2,CPE,FGFR3,PCDH9
8.681e-04-7.05lymphoid_neoplasmCOSMIC cancer mutationslymphoid_neoplasm12233451682849 TRPS1,NFIA,PARD3B,SORBS1,GPM6A,PREX2,CDH20,PAMR1,MSI2,NHSL1,ARHGAP24,NKAIN3,AMZ2,PCDH9,GLI3,FGFR3,ACSS1,FBXL7,COL5A3,DTNA,CLU,ABLIM1,PON2,MAML2,SPARCL1,GPC5,CTNND2,SLC1A2,RYR3,LSAMP,NTM,SLC4A4,QKI,ATP13A4,CPE,AQP4,MEIS2,NPAS3,SLC1A3,SPON1,PTPRZ1,BMPR1B,GLIS3,PITPNC1,MACF1
9.407e-04-6.97regulation of amyloid fibril formationbiological processGO:19059061721820449 CLU,APOE
9.407e-04-6.97reverse cholesterol transportbiological processGO:00436911721820449 CLU,APOE
9.985e-04-6.91regulation of cartilage developmentbiological processGO:00610357331820449 BMPR1B,TRPS1,GLI3
9.998e-04-6.91skin-trunk-malignant_melanoma-nodularCOSMIC cancer mutationsskin-trunk-malignant_melanoma-nodular1291111682849 PREX2,GLIS3,CTNND2,PTPRZ1,SPARCL1,MACF1,NPAS3,CPE,ATP13A4,ABLIM1,CDH20
1.022e-03-6.89Htt (huntingtin)protein interactions151947731945450 LSAMP,NTM,GPM6A
1.026e-03-6.88acidic amino acid transmembrane transporter activitymolecular functionGO:00151721821809448 SLC1A2,SLC1A3
1.069e-03-6.84oesophagus-carcinoma-squamous_cell_carcinomaCOSMIC cancer mutationsoesophagus-carcinoma-squamous_cell_carcinoma6486301682849 ABLIM1,MAML2,FBXL7,COL5A3,PCDH9,FGFR3,GLI3,ARHGAP24,SORBS1,GPM6A,PREX2,TRPS1,PARD3B,MACF1,PITPNC1,BMPR1B,GLIS3,SPON1,PTPRZ1,NDRG2,SLC4A4,AQP4,CPE,ATP13A4,MEIS2,NPAS3,CTNND2,RYR3,SPARCL1,GPC5
1.071e-03-6.84astrocyte projectioncellular componentGO:00974491921910849 AQP4,SLC1A2
1.077e-03-6.83RIT2 (Ras like without CAAX 2)protein interactions60141921945450 ARHGAP24,DTNA
1.158e-03-6.76superficial_spreadingCOSMIC cancer mutationssuperficial_spreading1110101682849 SORBS1,CTNND2,COL5A3,PREX2,FGFR3,GLI3,SLC4A4,ATP13A4,MACF1,NTM
1.179e-03-6.74regulation of amyloid-beta clearancebiological processGO:19002211921820449 CLU,APOE
1.194e-03-6.73PDZD2 (PDZ domain containing 2)protein interactions230372021945450 CTNND2,CST3
1.196e-03-6.73cartilage developmentbiological processGO:005121617341820449 BMPR1B,GLI3,FGFR3,NFIA
1.247e-03-6.69solute:sodium symporter activitymolecular functionGO:00153708031809448 SLC1A2,SLC1A3,SLC4A4
1.261e-03-6.68behaviorbiological processGO:000761061971820449 GLI3,PTPRZ1,MEIS2,APOE,SLC1A3,PREX2,SLC1A2
1.265e-03-6.67mouthCOSMIC cancer mutationsmouth9004371682849 GPC5,LSAMP,RYR3,CTNND2,SLC1A2,NTM,NPAS3,ATP13A4,QKI,SLC4A4,PTPRZ1,NDRG2,SPON1,SLC1A3,PITPNC1,MACF1,PARD3B,TRPS1,PREX2,GPM6A,SORBS1,NHSL1,PAMR1,CDH20,FGFR3,GLI3,CST3,PCDH9,AMZ2,COL5A3,ACSS1,FBXL7,APOE,MAML2,ABLIM1,CLU,DTNA
1.307e-03-6.64positive regulation of chondrocyte differentiationbiological processGO:00323322021820449 BMPR1B,GLI3
1.307e-03-6.64aspartate transmembrane transportbiological processGO:00158102021820449 SLC1A3,SLC1A2
1.318e-03-6.63TENM1 (teneurin transmembrane protein 1)protein interactions101782121945450 SORBS1,MACF1
1.349e-03-6.61regulation of amide metabolic processbiological processGO:00342488131820449 APOE,SPON1,CLU
1.398e-03-6.57pancreas-carcinoid-endocrine_tumourCOSMIC cancer mutationspancreas-carcinoid-endocrine_tumour7250321682849 GPM6A,PREX2,NHSL1,PAMR1,CDH20,PCDH9,NKAIN3,FGFR3,GLI3,COL5A3,ACSS1,FBXL7,APOE,CLU,ABLIM1,MAML2,PON2,GPC5,RYR3,CTNND2,SLC1A2,LSAMP,QKI,ATP13A4,CPE,SLC4A4,MEIS2,SPON1,SLC1A3,BMPR1B,GLIS3,MACF1
1.550e-03-6.47chondrocyte differentiationbiological processGO:00020628531820449 BMPR1B,GLI3,FGFR3
1.550e-03-6.47oligodendrocyte differentiationbiological processGO:00487098531820449 CLU,PTPRZ1,GLI3
1.570e-03-6.46upper_aerodigestive_tract-mouth-carcinoma-squamous_cell_carcinomaCOSMIC cancer mutationsupper_aerodigestive_tract-mouth-carcinoma-squamous_cell_carcinoma6953311682849 GLI3,FGFR3,CST3,PCDH9,FBXL7,ACSS1,MAML2,DTNA,ABLIM1,PARD3B,TRPS1,PREX2,SORBS1,GPM6A,PAMR1,CDH20,NHSL1,PTPRZ1,NDRG2,SPON1,PITPNC1,MACF1,GPC5,LSAMP,CTNND2,SLC1A2,RYR3,NTM,SLC4A4,QKI,ATP13A4
1.582e-03-6.45TIMM10B (translocase of inner mitochondrial membrane 10B)protein interactions265152321945450 MSI2,MEIS2
1.582e-03-6.45Rbm38 (RNA binding motif protein 38)protein interactions561902321945450 QKI,MSI2
1.603e-03-6.44transport across blood-brain barrierbiological processGO:01501048631820449 SLC1A3,SLC1A2,SLC4A4
1.603e-03-6.44vascular transportbiological processGO:00102328631820449 SLC4A4,SLC1A2,SLC1A3
1.636e-03-6.42haematopoietic_and_lymphoid_tissue-lymphoid_neoplasmCOSMIC cancer mutationshaematopoietic_and_lymphoid_tissue-lymphoid_neoplasm7307321682849 PON2,MAML2,CLU,ABLIM1,FBXL7,ACSS1,COL5A3,GLI3,NKAIN3,PCDH9,CDH20,PAMR1,NHSL1,PREX2,GPM6A,PARD3B,MACF1,GLIS3,BMPR1B,PTPRZ1,SLC1A3,SPON1,MEIS2,ATP13A4,CPE,QKI,LSAMP,SLC1A2,CTNND2,RYR3,SPARCL1,GPC5
1.683e-03-6.39amino acid:sodium symporter activitymolecular functionGO:00052832321809448 SLC1A2,SLC1A3
1.696e-03-6.38amyloid-beta bindingmolecular functionGO:00015408931809448 CST3,CLU,APOE
1.715e-03-6.37human chr17q24.2chromosome locationhuman chr17q24.23222613450 PITPNC1,AMZ2
1.748e-03-6.35parathyroid-carcinomaCOSMIC cancer mutationsparathyroid-carcinoma30051682849 MACF1,RYR3,GPC5,PAMR1,TRPS1
1.758e-03-6.34lung-right_lower_lobe-carcinoma-adenocarcinomaCOSMIC cancer mutationslung-right_lower_lobe-carcinoma-adenocarcinoma5692271682849 MACF1,SPON1,SLC1A3,PTPRZ1,NTM,ATP13A4,SLC4A4,NPAS3,MEIS2,GPC5,RYR3,CTNND2,LSAMP,CLU,DTNA,MAML2,NKAIN3,CST3,GLI3,COL5A3,FBXL7,CDH20,PAMR1,TRPS1,PARD3B,GPM6A,SORBS1
1.758e-03-6.34right_lower_lobeCOSMIC cancer mutationsright_lower_lobe5692271682849 ATP13A4,SLC4A4,NPAS3,MEIS2,NTM,RYR3,CTNND2,LSAMP,GPC5,MACF1,SPON1,SLC1A3,PTPRZ1,CDH20,PAMR1,GPM6A,SORBS1,TRPS1,PARD3B,CLU,DTNA,MAML2,COL5A3,FBXL7,NKAIN3,GLI3,CST3
1.832e-03-6.30low-density lipoprotein particle receptor bindingmolecular functionGO:00507502421809448 CLU,APOE
1.912e-03-6.26SOX2 (SRY-box transcription factor 2)protein interactions66571342101945450 NFIA,CLU,LSAMP,QKI,MEIS2,TRPS1,GLIS3,GLI3,MACF1,MSI2
1.913e-03-6.26human chr15q13.3-q14chromosome locationhuman chr15q13.3-q14112613450 RYR3
1.913e-03-6.26human chr4q21.23-q21.3chromosome locationhuman chr4q21.23-q21.3112613450 ARHGAP24
1.928e-03-6.25anchoring junctioncellular componentGO:007016190281910849 CDH20,PCDH9,CTNNA2,CTNND2,FGFR3,ARHGAP24,PARD3B,SORBS1
1.960e-03-6.23synapse organizationbiological processGO:005080833351820449 NFIA,CTNND2,GPM6A,APOE,SPARCL1
2.013e-03-6.21high-density lipoprotein particlecellular componentGO:00343642621910849 APOE,CLU
2.021e-03-6.20skin-face-malignant_melanoma-lentigo_malignaCOSMIC cancer mutationsskin-face-malignant_melanoma-lentigo_maligna2321682849 FGFR3,PREX2
2.023e-03-6.20CYP2C18 (cytochrome P450 family 2 subfamily C member 18)protein interactions15622621945450 AMZ2,APOE
2.047e-03-6.19positive regulation of amyloid precursor protein catabolic processbiological processGO:19029932521820449 CLU,SPON1
2.047e-03-6.19L-glutamate transmembrane transportbiological processGO:00158132521820449 SLC1A2,SLC1A3
2.118e-03-6.16regulation of Wnt signaling pathwaybiological processGO:003011133951820449 GPC5,CTNND2,MACF1,APOE,GLI3
2.152e-03-6.14extrinsic component of plasma membranecellular componentGO:001989710031910849 DTNA,CTNNA2,CDH20
2.181e-03-6.13KCNJ12 (potassium inwardly rectifying channel subfamily J member 12)protein interactions37682721945450 DTNA,ABLIM1
2.181e-03-6.13HPCAL4 (hippocalcin like 4)protein interactions514402721945450 GPM6A,AQP4
2.181e-03-6.13MBNL2 (muscleblind like splicing regulator 2)protein interactions101502721945450 MSI2,QKI
2.181e-03-6.13Glutamate Neurotransmitter Release CycleREACTOME pathwaysR-HSA-2105002421028530 SLC1A2,SLC1A3
2.214e-03-6.11C4-dicarboxylate transportbiological processGO:00157402621820449 SLC1A2,SLC1A3
2.247e-03-6.10PROKAR_LIPOPROTEINprosite domainsPS512577631218642 CPE,APOE,GLIS3
2.304e-03-6.07oesophagus-carcinomaCOSMIC cancer mutationsoesophagus-carcinoma4269221682849 SLC4A4,PTGDS,ATP13A4,NTM,CDH20,NHSL1,PREX2,SORBS1,CTNND2,GPM6A,RYR3,PARD3B,TRPS1,NFIA,MACF1,ACSS1,FBXL7,COL5A3,PTPRZ1,GLI3,FGFR3,PCDH9
2.398e-03-6.03bone morphogenesisbiological processGO:00603499931820449 FGFR3,GLI3,BMPR1B
2.412e-03-6.03haematopoietic_and_lymphoid_tissue-spleen-lymphoid_neoplasm-marginal_zone_lymphomaCOSMIC cancer mutationshaematopoietic_and_lymphoid_tissue-spleen-lymphoid_neoplasm-marginal_zone_lymphoma32351682849 SORBS1,MEIS2,PARD3B,PTPRZ1,NTM
2.447e-03-6.01boneCOSMIC cancer mutationsbone8157341682849 SLC4A4,QKI,CPE,ATP13A4,NPAS3,SPARCL1,GPC5,CTNND2,RYR3,LSAMP,MACF1,SLC1A3,SPON1,PTPRZ1,NDRG2,GLIS3,PAMR1,PTGDS,TRPS1,PARD3B,SORBS1,GPM6A,PREX2,DTNA,ABLIM1,PON2,MAML2,NKAIN3,PCDH9,FGFR3,CST3,GLI3,ACSS1,COL5A3
2.467e-03-6.00response to alkaloidbiological processGO:004327910031820449 SLC1A2,RYR3,SLC1A3
2.476e-03-6.00parathyroidCOSMIC cancer mutationsparathyroid47661682849 GPC5,PAMR1,TRPS1,MACF1,RYR3,GPM6A
2.564e-03-5.97perinuclear endoplasmic reticulum lumencellular componentGO:0099020111910849 CLU
2.566e-03-5.97positive regulation of oligodendrocyte differentiationbiological processGO:00487142821820449 PTPRZ1,QKI
2.566e-03-5.97glial cell proliferationbiological processGO:00140092821820449 NFIA,CLU
2.570e-03-5.96ZNF75D (zinc finger protein 75D)protein interactions7626111945450 ARHGAP24
2.570e-03-5.96ZNF880 (zinc finger protein 880)protein interactions400713111945450 ARHGAP24
2.570e-03-5.96ZNF780B (zinc finger protein 780B)protein interactions163131111945450 ARHGAP24
2.570e-03-5.96Isl1 (ISL1 transcription factor, LIM/homeodomain)protein interactions16392111945450 GLIS3
2.570e-03-5.96Hipk3 (homeodomain interacting protein kinase 3)protein interactions15259111945450 GLIS3
2.570e-03-5.96Sh2b1 (SH2B adaptor protein 1)protein interactions20399111945450 FGFR3
2.570e-03-5.961700006A11Rik (RIKEN cDNA 1700006A11 gene)protein interactions71824111945450 BMPR1B
2.570e-03-5.96Lztr1 (leucine-zipper-like transcriptional regulator, 1)protein interactions66863111945450 BMPR1B
2.570e-03-5.96ZNF781 (zinc finger protein 781)protein interactions163115111945450 ARHGAP24
2.570e-03-5.96Agtrap (angiotensin II, type I receptor-associated protein)protein interactions11610111945450 PITPNC1
2.570e-03-5.96fgf3.L (fibroblast growth factor 3 L homeolog)protein interactions373669111945450 FGFR3
2.570e-03-5.96Dcaf7 (DDB1 and CUL4 associated factor 7)protein interactions71833111945450 BMPR1B
2.570e-03-5.96ZNF729 (zinc finger protein 729)protein interactions100287226111945450 ARHGAP24
2.653e-03-5.93internal N(7)-methylguanine-containing RNA reader activitymolecular functionGO:0160089111809448 QKI
2.653e-03-5.93metal chelating activitymolecular functionGO:0046911111809448 APOE
2.671e-03-5.93human chr20p11.21chromosome locationhuman chr20p11.214022613450 CST3,ACSS1
2.673e-03-5.92amino acid:monoatomic cation symporter activitymolecular functionGO:00054162921809448 SLC1A2,SLC1A3
2.673e-03-5.92lipoprotein particle receptor bindingmolecular functionGO:00703252921809448 CLU,APOE
2.681e-03-5.92marginal_zone_lymphomaCOSMIC cancer mutationsmarginal_zone_lymphoma33151682849 MEIS2,SORBS1,PARD3B,NTM,PTPRZ1
2.692e-03-5.92intermediate-density lipoprotein particle clearancebiological processGO:0071831111820449 APOE
2.692e-03-5.92lateral semicircular canal developmentbiological processGO:0060875111820449 GLI3
2.692e-03-5.92sagittal suture morphogenesisbiological processGO:0060367111820449 GLI3
2.692e-03-5.92lambdoid suture morphogenesisbiological processGO:0060366111820449 GLI3
2.692e-03-5.92positive regulation of transport across blood-brain barrierbiological processGO:0150201111820449 APOE
2.692e-03-5.92regulation of lipid transport across blood-brain barrierbiological processGO:1903000111820449 APOE
2.692e-03-5.92regulation of heparan sulfate proteoglycan bindingbiological processGO:1905858111820449 APOE
2.692e-03-5.92subpallium cell proliferation in forebrainbiological processGO:0022012111820449 GLI3
2.692e-03-5.92lateral ganglionic eminence cell proliferationbiological processGO:0022018111820449 GLI3
2.692e-03-5.92positive regulation of neurofibrillary tangle assemblybiological processGO:1902998111820449 CLU
2.692e-03-5.92negative regulation of collagen catabolic processbiological processGO:0010711111820449 CST3
2.692e-03-5.92anterior semicircular canal developmentbiological processGO:0060873111820449 GLI3
2.692e-03-5.92regulation of neuronal signal transductionbiological processGO:1902847111820449 CLU
2.692e-03-5.92negative regulation of elastin catabolic processbiological processGO:0060311111820449 CST3
2.692e-03-5.92regulation of transport across blood-brain barrierbiological processGO:0150200111820449 APOE
2.692e-03-5.92positive regulation of lipid transport across blood-brain barrierbiological processGO:1903002111820449 APOE
2.692e-03-5.92regulation of cellular response to very-low-density lipoprotein particle stimulusbiological processGO:1905890111820449 APOE
2.692e-03-5.92positive regulation of heparan sulfate proteoglycan bindingbiological processGO:1905860111820449 APOE
2.700e-03-5.91TRPS1interpro domainsIPR028440111852150 TRPS1
2.700e-03-5.91SORBS1_SH3interpro domainsIPR035606111852150 SORBS1
2.700e-03-5.91Clusterin_CSinterpro domainsIPR033986111852150 CLU
2.700e-03-5.91STAR_dimerinterpro domainsIPR032377111852150 QKI
2.700e-03-5.91Quaking_NLSinterpro domainsIPR032367111852150 QKI
2.700e-03-5.91SPARC-like_p1interpro domainsIPR016359111852150 SPARCL1
2.700e-03-5.91SORBS1_SH3_2interpro domainsIPR035611111852150 SORBS1
2.700e-03-5.91Rex2_DEP_1interpro domainsIPR037367111852150 PREX2
2.700e-03-5.91Clusterininterpro domainsIPR016016111852150 CLU
2.700e-03-5.91SORBS1_SH3_1interpro domainsIPR035610111852150 SORBS1
2.700e-03-5.91M14_CPE_CPDinterpro domainsIPR034232111852150 CPE
2.700e-03-5.91MAML2_TADinterpro domainsIPR048452111852150 MAML2
2.709e-03-5.91large_intestine-caecum-carcinoma-adenocarcinomaCOSMIC cancer mutationslarge_intestine-caecum-carcinoma-adenocarcinoma14236481682849 PCDH9,NKAIN3,AMZ2,GLI3,FGFR3,DTNA,PON2,APOE,PREX2,PARD3B,CDH20,ARHGAP24,GLIS3,SPON1,SLC1A3,NDRG2,PTPRZ1,MACF1,PITPNC1,CTNND2,GPC5,QKI,ATP13A4,SLC4A4,MEIS2,NPAS3,NTM,COL5A3,FBXL7,ACSS1,CST3,ABLIM1,CLU,MAML2,GPM6A,SORBS1,NFIA,TRPS1,PTGDS,NHSL1,PAMR1,BMPR1B,RYR3,SLC1A2,LSAMP,SPARCL1,AQP4,CPE
2.809e-03-5.87caecumCOSMIC cancer mutationscaecum14248481682849 GLIS3,SLC1A3,SPON1,PTPRZ1,NDRG2,MACF1,PITPNC1,CTNND2,GPC5,SLC4A4,QKI,ATP13A4,NPAS3,MEIS2,NTM,AMZ2,NKAIN3,PCDH9,GLI3,FGFR3,DTNA,PON2,APOE,PREX2,PARD3B,CDH20,ARHGAP24,BMPR1B,SLC1A2,RYR3,LSAMP,SPARCL1,AQP4,CPE,ACSS1,FBXL7,COL5A3,CST3,CLU,ABLIM1,MAML2,SORBS1,GPM6A,TRPS1,NFIA,PTGDS,PAMR1,NHSL1
2.810e-03-5.87Peptidase_M54pfam domainsPF07998111779550 AMZ2
2.810e-03-5.87FGFR3_TMpfam domainsPF21165111779550 FGFR3
2.810e-03-5.87STAR_dimerpfam domainsPF16544111779550 QKI
2.810e-03-5.87Quaking_NLSpfam domainsPF16551111779550 QKI
2.810e-03-5.87MAML2_TADpfam domainsPF20804111779550 MAML2
2.857e-03-5.86cell bodycellular componentGO:004429755661910849 BMPR1B,CTNND2,SLC1A2,SLC1A3,GPM6A,APOE
2.857e-03-5.86catenin complexcellular componentGO:00163423121910849 CTNNA2,CDH20
2.862e-03-5.86ACTB (actin beta)protein interactions6095881945450 ABLIM1,ARHGAP24,MACF1,APOE,DTNA,NHSL1,MEIS2,SORBS1
2.917e-03-5.84t(4;14) translocations of FGFR3REACTOME pathwaysR-HSA-2033515111028530 FGFR3
2.942e-03-5.83L-glutamate importbiological processGO:00519383021820449 SLC1A2,SLC1A3
2.942e-03-5.83neurotransmitter uptakebiological processGO:00015043021820449 SLC1A3,SLC1A2
3.041e-03-5.80-gene3d domains6.10.250.1740111447044 FGFR3
3.041e-03-5.80-gene3d domains1.20.5.4010111447044 QKI
3.055e-03-5.79CDH1 (cadherin 1)protein interactions99975771945450 NDRG2,CTNND2,CTNNA2,ABLIM1,MACF1,NHSL1,SORBS1
3.072e-03-5.79upper_aerodigestive_tract-pharynx-carcinoma-squamous_cell_carcinomaCOSMIC cancer mutationsupper_aerodigestive_tract-pharynx-carcinoma-squamous_cell_carcinoma1485111682849 SORBS1,RYR3,PREX2,PCDH9,GPC5,PTPRZ1,FGFR3,PARD3B,DTNA,MACF1,NPAS3
3.219e-03-5.74skin-leg-malignant_melanoma-superficial_spreadingCOSMIC cancer mutationsskin-leg-malignant_melanoma-superficial_spreading21041682849 SLC4A4,ATP13A4,COL5A3,NTM
3.224e-03-5.74human chr11p13chromosome locationhuman chr11p134422613450 SLC1A2,PAMR1
3.249e-03-5.73VLDLR (very low density lipoprotein receptor)protein interactions74363321945450 CLU,APOE
3.249e-03-5.73KATNAL1 (katanin catalytic subunit A1 like 1)protein interactions840563321945450 PITPNC1,ARHGAP24
3.253e-03-5.73intestinal_adenocarcinomaCOSMIC cancer mutationsintestinal_adenocarcinoma7225311682849 PITPNC1,MACF1,SPON1,PTPRZ1,NTM,AQP4,ATP13A4,QKI,SLC4A4,MEIS2,NPAS3,RYR3,CTNND2,SLC1A2,LSAMP,CLU,MAML2,PCDH9,FGFR3,CST3,GLI3,COL5A3,FBXL7,ACSS1,NHSL1,CDH20,ARHGAP24,NFIA,TRPS1,PARD3B,PREX2
3.253e-03-5.73stomach-carcinoma-intestinal_adenocarcinomaCOSMIC cancer mutationsstomach-carcinoma-intestinal_adenocarcinoma7225311682849 COL5A3,FBXL7,ACSS1,PCDH9,GLI3,CST3,FGFR3,CLU,MAML2,PREX2,NFIA,TRPS1,PARD3B,NHSL1,CDH20,ARHGAP24,SPON1,PTPRZ1,MACF1,PITPNC1,RYR3,CTNND2,SLC1A2,LSAMP,AQP4,QKI,ATP13A4,SLC4A4,NPAS3,MEIS2,NTM
3.261e-03-5.73plasma membrane bounded cell projection organizationbiological processGO:0120036115291820449 PREX2,BMPR1B,PTPRZ1,GLI3,CTNNA2,ABLIM1,CTNND2,GPM6A,APOE
3.344e-03-5.70positive regulation of cartilage developmentbiological processGO:00610363221820449 GLI3,BMPR1B
3.344e-03-5.70transepithelial transportbiological processGO:00706333221820449 SLC1A3,SLC1A2
3.353e-03-5.70HNRNPL (heterogeneous nuclear ribonucleoprotein L)protein interactions31911958121945450 NFIA,FGFR3,QKI,TRPS1,ABLIM1,BMPR1B,PON2,DTNA,ARHGAP24,MACF1,MSI2,PARD3B
3.430e-03-5.68skin-malignant_melanoma-acral_lentiginousCOSMIC cancer mutationsskin-malignant_melanoma-acral_lentiginous3021682849 PREX2,FGFR3
3.430e-03-5.68lentigo_malignaCOSMIC cancer mutationslentigo_maligna3021682849 PREX2,FGFR3
3.447e-03-5.67CLUSTERIN_2prosite domainsPS00493111218642 CLU
3.447e-03-5.67CLUSTERIN_1prosite domainsPS00492111218642 CLU
3.465e-03-5.67CEACAM8 (CEA cell adhesion molecule 8)protein interactions108811831945450 CPE,APOE,CLU
3.476e-03-5.66connective tissue developmentbiological processGO:006144823241820449 GLI3,FGFR3,NFIA,BMPR1B
3.482e-03-5.66cell adhesion molecule bindingmolecular functionGO:005083956061809448 CDH20,CPE,CTNNA2,PTPRZ1,CTNND2,MACF1
3.486e-03-5.66dendrite developmentbiological processGO:001635811331820449 CTNNA2,CTNND2,PREX2
3.504e-03-5.65eye developmentbiological processGO:000165438151820449 GPM6A,BMPR1B,MEIS2,NFIA,GLI3
3.548e-03-5.64HLA-DPA1 (major histocompatibility complex, class II, DP alpha 1)protein interactions311311931945450 CLU,PCDH9,APOE
3.602e-03-5.63DELLAsmart domainsSM0112911971735 MACF1
3.615e-03-5.62trunkCOSMIC cancer mutationstrunk3554191682849 ABLIM1,MAML2,MACF1,SLC1A3,PCDH9,PTPRZ1,FGFR3,GLIS3,CDH20,ATP13A4,CPE,MEIS2,NPAS3,SPARCL1,TRPS1,CTNND2,RYR3,PREX2,LSAMP
3.624e-03-5.62Transport of inorganic cations/anions and amino acids/oligopeptidesREACTOME pathwaysR-HSA-42539310731028530 SLC4A4,SLC1A3,SLC1A2
3.663e-03-5.61fatty acid biosynthetic processbiological processGO:000663311531820449 PTGDS,ACSS1,QKI
3.663e-03-5.61visual system developmentbiological processGO:015006338551820449 NFIA,GLI3,MEIS2,BMPR1B,GPM6A
3.680e-03-5.60synapsecellular componentGO:00452021473101910849 GPM6A,APOE,SPARCL1,SLC1A3,PTPRZ1,CLU,DTNA,CTNND2,QKI,SLC1A2
3.688e-03-5.60solute:monoatomic cation symporter activitymolecular functionGO:001529411731809448 SLC4A4,SLC1A2,SLC1A3
3.826e-03-5.57AQUAPORIN4prints domainsPR0201611522720 AQP4
3.839e-03-5.56lipoprotein particlecellular componentGO:19907773621910849 CLU,APOE
3.839e-03-5.56plasma lipoprotein particlecellular componentGO:00343583621910849 APOE,CLU
3.878e-03-5.55organic acid:sodium symporter activitymolecular functionGO:00053433521809448 SLC1A3,SLC1A2
3.912e-03-5.54sensory system developmentbiological processGO:004888039151820449 MEIS2,BMPR1B,GPM6A,NFIA,GLI3
3.978e-03-5.53eye-uveal_tract-malignant_melanoma-spindleCOSMIC cancer mutationseye-uveal_tract-malignant_melanoma-spindle36351682849 CPE,CTNND2,PREX2,MACF1,PCDH9
3.990e-03-5.52neuron fate specificationbiological processGO:00486653521820449 GLI3,NFIA
4.052e-03-5.51glial cell projectioncellular componentGO:00973863721910849 SLC1A2,AQP4
4.071e-03-5.50HPCA (hippocalcin)protein interactions32083721945450 CST3,GPM6A
4.094e-03-5.50transporter activitymolecular functionGO:0005215121191809448 GPM6A,SLC1A2,SLC4A4,ATP13A4,AQP4,PITPNC1,APOE,SLC1A3,RYR3
4.099e-03-5.50proteoglycan bindingmolecular functionGO:00433943621809448 COL5A3,APOE
4.258e-03-5.46EPB41L4A (erythrocyte membrane protein band 4.1 like 4A)protein interactions6409712731945450 ABLIM1,MACF1,DTNA
4.275e-03-5.45cell projection organizationbiological processGO:0030030120091820449 BMPR1B,PREX2,ABLIM1,CTNNA2,CTNND2,GPM6A,APOE,PTPRZ1,GLI3
4.281e-03-5.45positive regulation of neurogenesisbiological processGO:005076924641820449 QKI,PTPRZ1,GLI3,MACF1
4.290e-03-5.45MMP3 (matrix metallopeptidase 3)protein interactions43143821945450 APOE,CLU
4.290e-03-5.45Pcbp1 (poly(rC) binding protein 1)protein interactions239833821945450 QKI,MSI2
4.391e-03-5.43central_nervous_system-parietal_lobe-glioma-astrocytoma_Grade_ICOSMIC cancer mutationscentral_nervous_system-parietal_lobe-glioma-astrocytoma_Grade_I3421682849 QKI,FGFR3
4.448e-03-5.42central_nervous_system-brainstem-glioma-oligoastrocytoma_Grade_IIICOSMIC cancer mutationscentral_nervous_system-brainstem-glioma-oligoastrocytoma_Grade_III11431682849 PREX2,SLC1A2,RYR3
4.451e-03-5.41positive regulation of glucose importbiological processGO:00463263721820449 SLC1A2,SORBS1
4.491e-03-5.41intracellular chemical homeostasisbiological processGO:005508258161820449 SLC4A4,AQP4,ATP13A4,APOE,RYR3,SLC1A3
4.493e-03-5.41protein-lipid complexcellular componentGO:00329943921910849 CLU,APOE
4.496e-03-5.40skin-face-carcinoma-squamous_cell_carcinomaCOSMIC cancer mutationsskin-face-carcinoma-squamous_cell_carcinoma2036131682849 PTPRZ1,FGFR3,PCDH9,MACF1,ABLIM1,TRPS1,GPC5,LSAMP,PREX2,GPM6A,ARHGAP24,MSI2,AQP4
4.691e-03-5.36amino acid import across plasma membranebiological processGO:00897183821820449 SLC1A3,SLC1A2
4.783e-03-5.34lung-carcinoma-small_cell_carcinomaCOSMIC cancer mutationslung-carcinoma-small_cell_carcinoma9908381682849 ARHGAP24,PAMR1,CDH20,MSI2,PARD3B,NFIA,TRPS1,PREX2,GPM6A,SORBS1,MAML2,ABLIM1,CLU,DTNA,GLI3,FGFR3,CST3,PCDH9,NKAIN3,COL5A3,FBXL7,NTM,NPAS3,MEIS2,CPE,ATP13A4,QKI,SLC4A4,GPC5,SPARCL1,RYR3,CTNND2,PITPNC1,MACF1,PTPRZ1,NDRG2,SPON1,BMPR1B
4.840e-03-5.33small_cell_carcinomaCOSMIC cancer mutationssmall_cell_carcinoma9913381682849 CDH20,PAMR1,MSI2,ARHGAP24,TRPS1,NFIA,PARD3B,SORBS1,GPM6A,PREX2,DTNA,CLU,ABLIM1,MAML2,NKAIN3,PCDH9,FGFR3,GLI3,CST3,FBXL7,COL5A3,NTM,SLC4A4,QKI,CPE,ATP13A4,MEIS2,NPAS3,SPARCL1,GPC5,CTNND2,RYR3,PITPNC1,MACF1,SPON1,NDRG2,PTPRZ1,BMPR1B
4.912e-03-5.32central_nervous_system-thalamus-glioma-astrocytoma_Grade_ICOSMIC cancer mutationscentral_nervous_system-thalamus-glioma-astrocytoma_Grade_I3621682849 FGFR3,QKI
4.918e-03-5.31cell differentiationbiological processGO:00301543645181820449 GLI3,GPM6A,NHSL1,CTNNA2,PREX2,NFIA,QKI,FGFR3,NDRG2,BMPR1B,NTM,PTPRZ1,APOE,CTNND2,SLC1A3,ARHGAP24,MSI2,CLU
4.936e-03-5.31positive regulation of nitric oxide biosynthetic processbiological processGO:00454293921820449 CLU,APOE
4.945e-03-5.31NUFIP1 (nuclear FMR1 interacting protein 1)protein interactions2674713431945450 NTM,GPM6A,CPE
4.963e-03-5.31cellular developmental processbiological processGO:00488693648181820449 MSI2,ARHGAP24,CLU,PTPRZ1,APOE,CTNND2,SLC1A3,PREX2,QKI,NFIA,FGFR3,NDRG2,BMPR1B,NTM,GLI3,GPM6A,NHSL1,CTNNA2
5.090e-03-5.28cation bindingmolecular functionGO:00431694341201809448 SLC1A3,APOE,ATP13A4,SPARCL1,TRPS1,DTNA,PON2,RYR3,PAMR1,BMPR1B,GLI3,MACF1,CPE,ACSS1,PCDH9,SPON1,ABLIM1,SLC1A2,AMZ2,GLIS3
5.122e-03-5.27discoidal high-density lipoprotein particlecellular componentGO:0034365211910849 APOE
5.122e-03-5.27chylomicron remnantcellular componentGO:0034360211910849 APOE
5.123e-03-5.27cell developmentbiological processGO:00484682236131820449 MSI2,CLU,PTPRZ1,APOE,CTNND2,SLC1A3,PREX2,QKI,BMPR1B,NTM,GLI3,GPM6A,CTNNA2
5.127e-03-5.27EF-hand-dom_pairinterpro domainsIPR01199225841852150 RYR3,MACF1,SPARCL1,DTNA
5.134e-03-5.27Irf7 (interferon regulatory factor 7)protein interactions54123211945450 BMPR1B
5.134e-03-5.27Klhl1 (kelch-like 1)protein interactions93688211945450 BMPR1B
5.134e-03-5.27Ppp3cc (protein phosphatase 3, catalytic subunit, gamma isoform)protein interactions19057211945450 BMPR1B
5.134e-03-5.27Fkbp1b (FK506 binding protein 1b)protein interactions14226211945450 BMPR1B
5.134e-03-5.27ZNF680 (zinc finger protein 680)protein interactions340252211945450 ARHGAP24
5.134e-03-5.27Bmpr2 (bone morphogenetic protein receptor type 2)protein interactions12168211945450 BMPR1B
5.134e-03-5.27Fkbp1a (FK506 binding protein 1a)protein interactions14225211945450 BMPR1B
5.134e-03-5.27Kdm4c (lysine (K)-specific demethylase 4C)protein interactions76804211945450 GLIS3
5.134e-03-5.27Bcr (BCR activator of RhoGEF and GTPase)protein interactions110279211945450 BMPR1B
5.134e-03-5.27Mknk2 (MAP kinase-interacting serine/threonine kinase 2)protein interactions17347211945450 BMPR1B
5.134e-03-5.27Sh3kbp1 (SH3-domain kinase binding protein 1)protein interactions58194211945450 BMPR1B
5.134e-03-5.27Fbxo34 (F-box protein 34)protein interactions78938211945450 BMPR1B
5.134e-03-5.27ZNF658B (zinc finger protein 658B (pseudogene))protein interactions401509211945450 ARHGAP24
5.134e-03-5.27Zmym2 (zinc finger, MYM-type 2)protein interactions76007211945450 GLIS3
5.184e-03-5.26central_nervous_system-third_ventricle-glioma-astrocytoma_Grade_ICOSMIC cancer mutationscentral_nervous_system-third_ventricle-glioma-astrocytoma_Grade_I3721682849 QKI,FGFR3
5.187e-03-5.26positive regulation of nitric oxide metabolic processbiological processGO:19044074021820449 APOE,CLU
5.198e-03-5.26RDX (radixin)protein interactions596227241945450 FGFR3,MACF1,ABLIM1,ARHGAP24
5.251e-03-5.25oligoastrocytoma_Grade_IICOSMIC cancer mutationsoligoastrocytoma_Grade_II12131682849 FGFR3,CDH20,DTNA
5.376e-03-5.23larynx developmentbiological processGO:0120224211820449 GLI3
5.376e-03-5.23regulation of neurofibrillary tangle assemblybiological processGO:1902996211820449 CLU
5.376e-03-5.23larynx morphogenesisbiological processGO:0120223211820449 GLI3
5.376e-03-5.23propionate biosynthetic processbiological processGO:0019542211820449 ACSS1
5.376e-03-5.23fibroblast growth factor receptor apoptotic signaling pathwaybiological processGO:1902178211820449 FGFR3
5.376e-03-5.23acetyl-CoA biosynthetic process from acetatebiological processGO:0019427211820449 ACSS1
5.376e-03-5.23regulation of elastin catabolic processbiological processGO:0060310211820449 CST3
5.376e-03-5.23lipid transport involved in lipid storagebiological processGO:0010877211820449 APOE
5.376e-03-5.23negative regulation of blood vessel remodelingbiological processGO:0060313211820449 CST3
5.376e-03-5.23negative regulation of 3'-UTR-mediated mRNA stabilizationbiological processGO:1905869211820449 QKI
5.376e-03-5.23mammary gland specificationbiological processGO:0060594211820449 GLI3
5.376e-03-5.23myofibroblast contractionbiological processGO:1990764211820449 QKI
5.376e-03-5.23smoothened signaling pathway involved in spinal cord motor neuron cell fate specificationbiological processGO:0021776211820449 GLI3
5.376e-03-5.23acetate biosynthetic processbiological processGO:0019413211820449 ACSS1
5.392e-03-5.22Pept_M54_archaemetzincninterpro domainsIPR012962211852150 AMZ2
5.392e-03-5.22MSI_RRM2interpro domainsIPR034126211852150 MSI2
5.392e-03-5.22Osteonectin_CSinterpro domainsIPR001999211852150 SPARCL1
5.392e-03-5.22Distrobrevininterpro domainsIPR017432211852150 DTNA
5.392e-03-5.22Clusterin_Ninterpro domainsIPR016014211852150 CLU
5.392e-03-5.22Spondin_N_sfinterpro domainsIPR038678211852150 SPON1
5.392e-03-5.22Clusterin_Cinterpro domainsIPR016015211852150 CLU
5.392e-03-5.22Alpha_CARP_receptor-typeinterpro domainsIPR041887211852150 PTPRZ1
5.392e-03-5.22Paraoxonase2interpro domainsIPR008364211852150 PON2
5.392e-03-5.22Ac_CoA_liginterpro domainsIPR011904211852150 ACSS1
5.392e-03-5.22Clusterin-likeinterpro domainsIPR000753211852150 CLU
5.392e-03-5.22Par3/HAL_Ninterpro domainsIPR021922211852150 PARD3B
5.392e-03-5.22Spondin_Ninterpro domainsIPR009465211852150 SPON1
5.432e-03-5.22Ig_I-setinterpro domainsIPR01309813231852150 FGFR3,NTM,LSAMP
5.461e-03-5.21central_nervous_system-brainstem-glioma-astrocytoma_Grade_ICOSMIC cancer mutationscentral_nervous_system-brainstem-glioma-astrocytoma_Grade_I3821682849 QKI,FGFR3
5.545e-03-5.19neutral L-amino acid transmembrane transporter activitymolecular functionGO:00151754221809448 SLC1A2,SLC1A3
5.565e-03-5.19regulation of canonical Wnt signaling pathwaybiological processGO:006082826541820449 CTNND2,APOE,GPC5,GLI3
5.612e-03-5.18Spond_Npfam domainsPF06468211779550 SPON1
5.612e-03-5.18Clusterinpfam domainsPF01093211779550 CLU
5.612e-03-5.18Reelerpfam domainsPF02014211779550 SPON1
5.612e-03-5.18Par3_HAL_N_termpfam domainsPF12053211779550 PARD3B
5.696e-03-5.17UPK2 (uroplakin 2)protein interactions737914131945450 CTNNA2,PON2,PCDH9
5.721e-03-5.16intracellular monoatomic cation homeostasisbiological processGO:003000342851820449 SLC1A3,APOE,RYR3,SLC4A4,ATP13A4
5.767e-03-5.16sarcolemmacellular componentGO:004238314231910849 AQP4,RYR3,DTNA
5.802e-03-5.15mast_cell_neoplasmCOSMIC cancer mutationsmast_cell_neoplasm24841682849 NPAS3,PCDH9,NFIA,GPC5
5.802e-03-5.15haematopoietic_and_lymphoid_tissue-haematopoietic_neoplasm-mast_cell_neoplasmCOSMIC cancer mutationshaematopoietic_and_lymphoid_tissue-haematopoietic_neoplasm-mast_cell_neoplasm24841682849 NFIA,GPC5,PCDH9,NPAS3
5.806e-03-5.15tau protein bindingmolecular functionGO:00481564321809448 CLU,APOE
5.885e-03-5.14central_nervous_system-brain-glioma-oligodendroglioma_Grade_IIICOSMIC cancer mutationscentral_nervous_system-brain-glioma-oligodendroglioma_Grade_III24941682849 MACF1,GLIS3,FGFR3,PTPRZ1
5.890e-03-5.13response to woundingbiological processGO:000961143151820449 NFIA,ARHGAP24,SLC1A3,MACF1,SLC1A2
5.935e-03-5.13active monoatomic ion transmembrane transporter activitymolecular functionGO:002285327441809448 SLC4A4,ATP13A4,SLC1A2,SLC1A3
6.018e-03-5.11carboxylic acid biosynthetic processbiological processGO:004639427141820449 PTGDS,SLC1A3,ACSS1,QKI
6.064e-03-5.11I-setpfam domainsPF0767913231779550 FGFR3,LSAMP,NTM
6.073e-03-5.10F-spondin domaingene3d domains2.60.40.2130211447044 SPON1
6.073e-03-5.10Vinculin, Vh2 four-helix bundlegene3d domains1.20.120.810211447044 CTNNA2
6.073e-03-5.10-gene3d domains6.20.350.10211447044 RYR3
6.098e-03-5.10scalpCOSMIC cancer mutationsscalp2110131682849 PTPRZ1,FGFR3,COL5A3,MACF1,TRPS1,NFIA,GPC5,SORBS1,LSAMP,PREX2,NTM,SLC4A4,ATP13A4
6.107e-03-5.10axoncellular componentGO:003042465061910849 GPM6A,PCDH9,DTNA,NDRG2,SLC1A2,CTNNA2
6.141e-03-5.09metal ion transmembrane transporter activitymolecular functionGO:004687344251809448 SLC4A4,GPM6A,SLC1A2,SLC1A3,RYR3
6.159e-03-5.09monoatomic cation transmembrane transporter activitymolecular functionGO:000832463061809448 RYR3,SLC1A3,SLC1A2,ATP13A4,GPM6A,SLC4A4
6.174e-03-5.09vascular process in circulatory systembiological processGO:000301827341820449 SLC1A3,APOE,SLC1A2,SLC4A4
6.238e-03-5.08intracellular monoatomic ion homeostasisbiological processGO:000687343751820449 APOE,RYR3,SLC1A3,SLC4A4,ATP13A4
6.247e-03-5.08positive regulation of glucose transmembrane transportbiological processGO:00108284421820449 SORBS1,SLC1A2
6.254e-03-5.07organic acid biosynthetic processbiological processGO:001605327441820449 ACSS1,QKI,PTGDS,SLC1A3
6.272e-03-5.07DSCR9 (Down syndrome critical region 9)protein interactions25720314631945450 SPARCL1,CLU,MACF1
6.493e-03-5.04spleenCOSMIC cancer mutationsspleen40851682849 PARD3B,NTM,PTPRZ1,MEIS2,SORBS1
6.500e-03-5.04CNTN1 (contactin 1)protein interactions12724721945450 PTPRZ1,GPM6A
6.527e-03-5.03acidic amino acid transportbiological processGO:00158004521820449 SLC1A2,SLC1A3
6.588e-03-5.02monoatomic anion transmembrane transportbiological processGO:009865614231820449 SLC1A2,SLC1A3,SLC4A4
6.588e-03-5.02positive regulation of small molecule metabolic processbiological processGO:006201314231820449 APOE,SORBS1,SLC4A4
6.760e-03-5.00pseudomyxoma_peritoneiCOSMIC cancer mutationspseudomyxoma_peritonei58561682849 FGFR3,TRPS1,MEIS2,COL5A3,MACF1,FBXL7
6.760e-03-5.00peritoneum-appendix-other-pseudomyxoma_peritoneiCOSMIC cancer mutationsperitoneum-appendix-other-pseudomyxoma_peritonei58561682849 MEIS2,MACF1,TRPS1,FGFR3,FBXL7,COL5A3
6.812e-03-4.99positive regulation of glial cell differentiationbiological processGO:00456874621820449 QKI,PTPRZ1
6.812e-03-4.99regulation of oligodendrocyte differentiationbiological processGO:00487134621820449 PTPRZ1,QKI
6.815e-03-4.99appendixCOSMIC cancer mutationsappendix58661682849 FBXL7,MACF1,MEIS2,COL5A3,FGFR3,TRPS1
6.841e-03-4.98faceCOSMIC cancer mutationsface2139131682849 ABLIM1,AQP4,MACF1,MSI2,ARHGAP24,GPM6A,LSAMP,PREX2,TRPS1,PCDH9,GPC5,PTPRZ1,FGFR3
6.870e-03-4.98uveal_tractCOSMIC cancer mutationsuveal_tract58761682849 FGFR3,PCDH9,PREX2,MACF1,CTNND2,CPE
6.870e-03-4.98peritoneumCOSMIC cancer mutationsperitoneum58761682849 TRPS1,FGFR3,FBXL7,COL5A3,MACF1,MEIS2
6.882e-03-4.98OSTEONECTIN_2prosite domainsPS00613211218642 SPARCL1
6.882e-03-4.98SPONDINprosite domainsPS51020211218642 SPON1
6.882e-03-4.98OSTEONECTIN_1prosite domainsPS00612211218642 SPARCL1
6.997e-03-4.96Wnt signaling pathwaybiological processGO:001605528341820449 CPE,NDRG2,MACF1,CTNND2
7.049e-03-4.95HBZ (hemoglobin subunit zeta)protein interactions30504921945450 ARHGAP24,FGFR3
7.087e-03-4.95symporter activitymolecular functionGO:001529314831809448 SLC4A4,SLC1A3,SLC1A2
7.119e-03-4.94oligoastrocytoma_Grade_IIICOSMIC cancer mutationsoligoastrocytoma_Grade_III26341682849 FGFR3,PREX2,RYR3,SLC1A2
7.191e-03-4.93CLasmart domainsSM0003521971735 CLU
7.191e-03-4.93CLbsmart domainsSM0003021971735 CLU
7.211e-03-4.93Retinoid metabolism and transportREACTOME pathwaysR-HSA-9756344421028530 APOE,GPC5
7.263e-03-4.92NMT1 (N-myristoyltransferase 1)protein interactions483615431945450 ARHGAP24,ABLIM1,DTNA
7.266e-03-4.92soft_tissue-striated_muscle-rhabdomyosarcomaCOSMIC cancer mutationssoft_tissue-striated_muscle-rhabdomyosarcoma59461682849 MACF1,TRPS1,SPON1,CTNND2,COL5A3,PREX2
7.272e-03-4.92Ig_3pfam domainsPF1392714131779550 NTM,LSAMP,FGFR3
7.306e-03-4.92Statin PathwayWikiPathwaysWP430332531021 ACSS1,APOE
7.404e-03-4.91large_intestine-adenomaCOSMIC cancer mutationslarge_intestine-adenoma26641682849 RYR3,GLI3,APOE,CDH20
7.493e-03-4.89cell surfacecellular componentGO:000998689671910849 CLU,SLC1A3,SLC1A2,GPC5,AQP4,SLC4A4,FGFR3
7.592e-03-4.88third_ventricleCOSMIC cancer mutationsthird_ventricle4521682849 FGFR3,QKI
7.617e-03-4.88Ndc80 (NDC80 kinetochore complex component)protein interactions670525121945450 MACF1,NHSL1
7.617e-03-4.88LINGO1 (leucine rich repeat and Ig domain containing 1)protein interactions848945121945450 NTM,PON2
7.631e-03-4.88human chr8q23.3chromosome locationhuman chr8q23.3412613450 TRPS1
7.639e-03-4.87PARAOXONASE2prints domainsPR0178721522720 PON2
7.691e-03-4.87Atg16l1 (autophagy related 16 like 1)protein interactions77040311945450 BMPR1B
7.691e-03-4.87Smad6 (SMAD family member 6)protein interactions17130311945450 BMPR1B
7.691e-03-4.87IL34 (interleukin 34)protein interactions146433311945450 PTPRZ1
7.691e-03-4.87ZNF257 (zinc finger protein 257)protein interactions113835311945450 ARHGAP24
7.691e-03-4.87QRFPR (pyroglutamylated RFamide peptide receptor)protein interactions84109311945450 NTM
7.691e-03-4.87ZNF506 (zinc finger protein 506)protein interactions440515311945450 ARHGAP24
7.691e-03-4.87Hk2 (hexokinase 2)protein interactions25059311945450 PTGDS
7.691e-03-4.87Lep (leptin)protein interactions16846311945450 CLU
7.691e-03-4.87BCO1 (beta-carotene oxygenase 1)protein interactions53630311945450 ABLIM1
7.691e-03-4.87Chn1 (chimerin 1)protein interactions108699311945450 BMPR1B
7.691e-03-4.87PIGL (phosphatidylinositol glycan anchor biosynthesis class L)protein interactions9487311945450 MEIS2
7.691e-03-4.87Shh (sonic hedgehog)protein interactions20423311945450 GLI3
7.691e-03-4.87Fbxw5 (F-box and WD-40 domain protein 5)protein interactions30839311945450 BMPR1B
7.691e-03-4.87ZNF540 (zinc finger protein 540)protein interactions163255311945450 ARHGAP24
7.691e-03-4.87ZNF682 (zinc finger protein 682)protein interactions91120311945450 ARHGAP24
7.691e-03-4.87Rap2a (RAS related protein 2a)protein interactions76108311945450 BMPR1B
7.691e-03-4.87ZNF716 (zinc finger protein 716)protein interactions441234311945450 ARHGAP24
7.691e-03-4.87Spop (speckle-type BTB/POZ protein)protein interactions20747311945450 GLIS3
7.691e-03-4.87Plekhb1 (pleckstrin homology domain containing, family B (evectins) member 1)protein interactions27276311945450 BMPR1B
7.691e-03-4.87Stk35 (serine/threonine kinase 35)protein interactions67333311945450 BMPR1B
7.691e-03-4.87Usp45 (ubiquitin specific petidase 45)protein interactions77593311945450 BMPR1B
7.700e-03-4.87astrocytoma_Grade_ICOSMIC cancer mutationsastrocytoma_Grade_I13931682849 QKI,FGFR3,GPC5
7.750e-03-4.86diffuse_adenocarcinomaCOSMIC cancer mutationsdiffuse_adenocarcinoma4383211682849 PON2,MACF1,DTNA,CLU,ABLIM1,PTPRZ1,FGFR3,GLI3,SLC1A3,SPON1,PCDH9,ACSS1,GLIS3,NHSL1,MEIS2,QKI,TRPS1,PREX2,CTNND2,RYR3,GPM6A
7.750e-03-4.86stomach-carcinoma-diffuse_adenocarcinomaCOSMIC cancer mutationsstomach-carcinoma-diffuse_adenocarcinoma4383211682849 RYR3,GPM6A,CTNND2,PREX2,TRPS1,QKI,MEIS2,NHSL1,ACSS1,GLIS3,PCDH9,SPON1,SLC1A3,FGFR3,GLI3,PTPRZ1,CLU,ABLIM1,DTNA,MACF1,PON2
7.761e-03-4.86C20 prostanoid biosynthesisBIOCYC pathwaysMETA_PWY66-374719021 PTGDS
7.761e-03-4.86C20 prostanoid biosynthesisBIOCYC pathwaysHUMAN_PWY66-374719021 PTGDS
7.928e-03-4.84TYRO3 (TYRO3 protein tyrosine kinase)protein interactions730115931945450 SLC1A3,CLU,APOE
7.938e-03-4.84lactonohydrolase activitymolecular functionGO:0046573311809448 PON2
7.938e-03-4.84acyl-L-homoserine-lactone lactonohydrolase activitymolecular functionGO:0102007311809448 PON2
7.938e-03-4.84cysteine transmembrane transporter activitymolecular functionGO:0033229311809448 SLC1A2
7.938e-03-4.84prostaglandin-D synthase activitymolecular functionGO:0004667311809448 PTGDS
7.984e-03-4.83eyeCOSMIC cancer mutationseye60661682849 PCDH9,FGFR3,CTNND2,PREX2,CPE,MACF1
8.029e-03-4.82stomach-adenocarcinomaCOSMIC cancer mutationsstomach-adenocarcinoma4101201682849 SLC4A4,QKI,ATP13A4,MEIS2,CDH20,PAMR1,CTNND2,SLC1A2,PREX2,TRPS1,GPC5,PARD3B,ABLIM1,PON2,MACF1,ACSS1,COL5A3,PCDH9,GLI3,FGFR3
8.054e-03-4.82cysteine transportbiological processGO:0042883311820449 SLC1A2
8.054e-03-4.82immune complex clearancebiological processGO:0002434311820449 CLU
8.054e-03-4.82acetate metabolic processbiological processGO:0006083311820449 ACSS1
8.054e-03-4.82regulation of platelet-derived growth factor productionbiological processGO:0090361311820449 NDRG2
8.054e-03-4.82smoothened signaling pathway involved in ventral spinal cord interneuron specificationbiological processGO:0021775311820449 GLI3
8.054e-03-4.82radial glia guided migration of Purkinje cellbiological processGO:0021942311820449 CTNNA2
8.054e-03-4.82cysteine transmembrane transportbiological processGO:1903712311820449 SLC1A2
8.054e-03-4.82positive regulation of low-density lipoprotein particle receptor catabolic processbiological processGO:0032805311820449 APOE
8.054e-03-4.82smoothened signaling pathway involved in ventral spinal cord patterningbiological processGO:0021910311820449 GLI3
8.054e-03-4.82protein targeting to lysosome involved in chaperone-mediated autophagybiological processGO:0061740311820449 CLU
8.054e-03-4.82very-low-density lipoprotein particle clearancebiological processGO:0034447311820449 APOE
8.054e-03-4.82nose morphogenesisbiological processGO:0043585311820449 GLI3
8.078e-03-4.82Arylesteraseinterpro domainsIPR002640311852150 PON2
8.078e-03-4.82Mastermind-like_Ninterpro domainsIPR019082311852150 MAML2
8.078e-03-4.82Ryanodine_rcptinterpro domainsIPR003032311852150 RYR3
8.078e-03-4.82MAML1-3interpro domainsIPR046369311852150 MAML2
8.078e-03-4.82SoHo_dominterpro domainsIPR003127311852150 SORBS1
8.078e-03-4.82MAML_N_sfinterpro domainsIPR046370311852150 MAML2
8.078e-03-4.82SPRY3_RyRinterpro domainsIPR035762311852150 RYR3
8.078e-03-4.82Myelin_PLP_CSinterpro domainsIPR018237311852150 GPM6A
8.078e-03-4.82Ryanrecept_TM4-6interpro domainsIPR009460311852150 RYR3
8.078e-03-4.82Vinculin_CSinterpro domainsIPR000633311852150 CTNNA2
8.078e-03-4.82Ryan_receptinterpro domainsIPR013333311852150 RYR3
8.078e-03-4.82Myelin_PLPinterpro domainsIPR001614311852150 GPM6A
8.078e-03-4.82SPRY2_RyRinterpro domainsIPR035764311852150 RYR3
8.078e-03-4.82RYDR_Jsolinterpro domainsIPR048581311852150 RYR3
8.078e-03-4.82SPRY1_RyRinterpro domainsIPR035761311852150 RYR3
8.078e-03-4.82Reeler_sfinterpro domainsIPR042307311852150 SPON1
8.078e-03-4.82Reeler_dominterpro domainsIPR002861311852150 SPON1
8.124e-03-4.81neuronal cell bodycellular componentGO:004302548951910849 APOE,GPM6A,SLC1A3,CTNND2,BMPR1B
8.172e-03-4.81positive regulation of nervous system developmentbiological processGO:005196229641820449 QKI,PTPRZ1,GLI3,MACF1
8.406e-03-4.78RYDR_Jsolpfam domainsPF21119311779550 RYR3
8.406e-03-4.78SR_plectin_7pfam domainsPF21097311779550 MACF1
8.406e-03-4.78RR_TM4-6pfam domainsPF06459311779550 RYR3
8.406e-03-4.78Myelin_PLPpfam domainsPF01275311779550 GPM6A
8.406e-03-4.78MamL-1pfam domainsPF09596311779550 MAML2
8.406e-03-4.78Arylesterasepfam domainsPF01731311779550 PON2
8.406e-03-4.78RyRpfam domainsPF02026311779550 RYR3
8.406e-03-4.78Sorbpfam domainsPF02208311779550 SORBS1
8.476e-03-4.77sodium ion transmembrane transporter activitymolecular functionGO:001508115831809448 SLC4A4,SLC1A3,SLC1A2
8.519e-03-4.77extracellular regioncellular componentGO:00055764350191910849 PTPRZ1,COL5A3,NTM,SPON1,SLC4A4,FGFR3,GPM6A,LSAMP,CPE,PTGDS,PAMR1,PON2,CST3,CLU,GPC5,NDRG2,APOE,AQP4,SPARCL1
8.525e-03-4.76retina development in camera-type eyebiological processGO:006004115631820449 BMPR1B,GPM6A,NFIA
8.573e-03-4.76upper_aerodigestive_tract-larynx-carcinoma-squamous_cell_carcinomaCOSMIC cancer mutationsupper_aerodigestive_tract-larynx-carcinoma-squamous_cell_carcinoma1946121682849 MAML2,MACF1,COL5A3,BMPR1B,FGFR3,GLI3,PCDH9,NPAS3,SLC4A4,RYR3,GPM6A,PARD3B
8.641e-03-4.75larynxCOSMIC cancer mutationslarynx1948121682849 PARD3B,GPM6A,RYR3,NPAS3,SLC4A4,FGFR3,GLI3,PCDH9,COL5A3,BMPR1B,MAML2,MACF1
8.710e-03-4.74growth conecellular componentGO:003042616531910849 PCDH9,GPM6A,NDRG2
8.711e-03-4.74skin-trunk-other-seborrhoeic_keratosisCOSMIC cancer mutationsskin-trunk-other-seborrhoeic_keratosis311682849 FGFR3
8.711e-03-4.74lentigoCOSMIC cancer mutationslentigo311682849 FGFR3
8.711e-03-4.74skin-leg-lentigoCOSMIC cancer mutationsskin-leg-lentigo311682849 FGFR3
8.711e-03-4.74skin-forearm-lentigoCOSMIC cancer mutationsskin-forearm-lentigo311682849 FGFR3
8.711e-03-4.74urinary_tract-bladder-papillomaCOSMIC cancer mutationsurinary_tract-bladder-papilloma311682849 FGFR3
8.711e-03-4.74skin-face-lentigoCOSMIC cancer mutationsskin-face-lentigo311682849 FGFR3
8.711e-03-4.74skin-trunk-lentigoCOSMIC cancer mutationsskin-trunk-lentigo311682849 FGFR3
8.711e-03-4.74skin-hand-lentigoCOSMIC cancer mutationsskin-hand-lentigo311682849 FGFR3
8.711e-03-4.74skin-leg-other-seborrhoeic_keratosisCOSMIC cancer mutationsskin-leg-other-seborrhoeic_keratosis311682849 FGFR3
8.711e-03-4.74skin-lentigoCOSMIC cancer mutationsskin-lentigo311682849 FGFR3
8.726e-03-4.74GLI proteins bind promoters of Hh responsive genes to promote transcriptionREACTOME pathwaysR-HSA-5635851311028530 GLI3
8.962e-03-4.71neutral amino acid transportbiological processGO:00158045321820449 SLC1A3,SLC1A2
8.979e-03-4.71monoatomic anion transportbiological processGO:000682015931820449 SLC4A4,SLC1A3,SLC1A2
9.087e-03-4.70metal ion bindingmolecular functionGO:00468724239191809448 RYR3,PON2,DTNA,TRPS1,ATP13A4,SPARCL1,APOE,SLC1A3,GLI3,MACF1,BMPR1B,PAMR1,ABLIM1,SPON1,PCDH9,CPE,GLIS3,AMZ2,SLC1A2
9.095e-03-4.70-gene3d domains6.10.250.970311447044 MAML2
9.095e-03-4.70-gene3d domains6.10.250.2510311447044 CTNNA2
9.095e-03-4.70Reeler domaingene3d domains2.60.40.4060311447044 SPON1
9.095e-03-4.70-gene3d domains1.10.490.160311447044 RYR3
9.142e-03-4.69cervix-carcinoma-squamous_cell_carcinomaCOSMIC cancer mutationscervix-carcinoma-squamous_cell_carcinoma11789421682849 ARHGAP24,NHSL1,CDH20,PAMR1,PREX2,GPM6A,SORBS1,PARD3B,NFIA,TRPS1,MAML2,PON2,ABLIM1,DTNA,COL5A3,ACSS1,FBXL7,FGFR3,GLI3,CST3,PCDH9,AMZ2,NPAS3,MEIS2,ATP13A4,CPE,QKI,SLC4A4,NTM,LSAMP,RYR3,CTNND2,SLC1A2,GPC5,SPARCL1,MACF1,PITPNC1,GLIS3,BMPR1B,PTPRZ1,SPON1,SLC1A3
9.191e-03-4.69EF-handgene3d domains1.10.238.1027241447044 SPARCL1,MACF1,RYR3,DTNA
9.227e-03-4.69cervixCOSMIC cancer mutationscervix11793421682849 ABLIM1,DTNA,MAML2,PON2,PCDH9,AMZ2,FGFR3,CST3,GLI3,COL5A3,FBXL7,ACSS1,NHSL1,CDH20,PAMR1,ARHGAP24,NFIA,TRPS1,PARD3B,GPM6A,SORBS1,PREX2,PITPNC1,MACF1,SPON1,SLC1A3,PTPRZ1,BMPR1B,GLIS3,NTM,ATP13A4,QKI,CPE,SLC4A4,NPAS3,MEIS2,GPC5,SPARCL1,RYR3,CTNND2,SLC1A2,LSAMP
9.290e-03-4.68negative regulation of supramolecular fiber organizationbiological processGO:190290416131820449 CLU,CTNNA2,APOE
9.446e-03-4.66site of polarized growthcellular componentGO:003042717031910849 GPM6A,PCDH9,NDRG2
9.513e-03-4.66NNT (nicotinamide nucleotide transhydrogenase)protein interactions2353017031945450 ARHGAP24,PON2,APOE
9.597e-03-4.65Neurotransmitter Release CycleREACTOME pathwaysR-HSA-1123105121028530 SLC1A2,SLC1A3
9.613e-03-4.64Amyotrophic lateral sclerosis (ALS)WikiPathwaysWP2447382531021 CST3,SLC1A2
9.625e-03-4.64intermembrane lipid transferbiological processGO:01200095521820449 APOE,PITPNC1
9.625e-03-4.64response to cocainebiological processGO:00422205521820449 SLC1A2,SLC1A3
9.665e-03-4.64TLX1 (T cell leukemia homeobox 1)protein interactions319517131945450 NFIA,MEIS2,TRPS1
9.687e-03-4.64lipid transfer activitymolecular functionGO:01200135621809448 PITPNC1,APOE
9.929e-03-4.61monocarboxylic acid biosynthetic processbiological processGO:007233016531820449 ACSS1,QKI,PTGDS
1.005e-02-4.60organic substance transportbiological processGO:00717021881111820449 ATP13A4,CPE,GLI3,SLC1A3,MACF1,PITPNC1,APOE,QKI,CLU,SLC4A4,SLC1A2
1.008e-02-4.60cellular homeostasisbiological processGO:001972568961820449 SLC1A3,APOE,RYR3,AQP4,SLC4A4,ATP13A4
1.009e-02-4.60HBA1 (hemoglobin subunit alpha 1)protein interactions30395921945450 CLU,ARHGAP24
1.009e-02-4.60VEGFA (vascular endothelial growth factor A)protein interactions74225921945450 CLU,PTPRZ1
1.022e-02-4.58extrinsic component of membranecellular componentGO:001989817531910849 CTNNA2,DTNA,CDH20
1.022e-02-4.58GLI-SUFU complexcellular componentGO:1990788411910849 GLI3
1.022e-02-4.58intermediate-density lipoprotein particlecellular componentGO:0034363411910849 APOE
1.022e-02-4.58collagen type V trimercellular componentGO:0005588411910849 COL5A3
1.024e-02-4.58Dnaja1 (DnaJ heat shock protein family (Hsp40) member A1)protein interactions15502411945450 GLIS3
1.024e-02-4.58CCDC126 (coiled-coil domain containing 126)protein interactions90693411945450 GPM6A
1.024e-02-4.58Ctbp2 (C-terminal binding protein 2)protein interactions13017411945450 TRPS1
1.024e-02-4.58ZNF879 (zinc finger protein 879)protein interactions345462411945450 ARHGAP24
1.024e-02-4.58Ilkap (integrin-linked kinase-associated serine/threonine phosphatase 2C)protein interactions67444411945450 BMPR1B
1.024e-02-4.58Rhebl1 (Ras homolog enriched in brain like 1)protein interactions69159411945450 BMPR1B
1.024e-02-4.58Arhgef6 (Rac/Cdc42 guanine nucleotide exchange factor 6)protein interactions73341411945450 BMPR1B
1.024e-02-4.58ZNF615 (zinc finger protein 615)protein interactions284370411945450 ARHGAP24
1.024e-02-4.58ZNF749 (zinc finger protein 749)protein interactions388567411945450 ARHGAP24
1.024e-02-4.58Cdk14 (cyclin dependent kinase 14)protein interactions18647411945450 BMPR1B
1.024e-02-4.58Srgap1 (SLIT-ROBO Rho GTPase activating protein 1)protein interactions117600411945450 BMPR1B
1.024e-02-4.58Nkiras1 (NFKB inhibitor interacting Ras-like protein 1)protein interactions69721411945450 BMPR1B
1.024e-02-4.58Naa20 (N(alpha)-acetyltransferase 20, NatB catalytic subunit)protein interactions67877411945450 BMPR1B
1.024e-02-4.58Sufu (SUFU negative regulator of hedgehog signaling)protein interactions24069411945450 GLI3
1.030e-02-4.58VINCULIN_1prosite domainsPS00663311218642 CTNNA2
1.030e-02-4.58SOHOprosite domainsPS50831311218642 SORBS1
1.030e-02-4.58MYELIN_PLP_2prosite domainsPS01004311218642 GPM6A
1.030e-02-4.58REELINprosite domainsPS51019311218642 SPON1
1.030e-02-4.58MYELIN_PLP_1prosite domainsPS00575311218642 GPM6A
1.031e-02-4.57visual behaviorbiological processGO:00076325721820449 SLC1A2,MEIS2
1.034e-02-4.57Metabolism of fat-soluble vitaminsREACTOME pathwaysR-HSA-68066675321028530 GPC5,APOE
1.042e-02-4.56SNTB1 (syntrophin beta 1)protein interactions66416021945450 DTNA,FGFR3
1.057e-02-4.55acetate-CoA ligase activitymolecular functionGO:0003987411809448 ACSS1
1.057e-02-4.55very-low-density lipoprotein particle receptor bindingmolecular functionGO:0070326411809448 APOE
1.057e-02-4.55ryanodine-sensitive calcium-release channel activitymolecular functionGO:0005219411809448 RYR3
1.057e-02-4.55mediator complex bindingmolecular functionGO:0036033411809448 GLI3
1.057e-02-4.55propionate-CoA ligase activitymolecular functionGO:0050218411809448 ACSS1
1.057e-02-4.55short-chain fatty acid-CoA ligase activitymolecular functionGO:0031955411809448 ACSS1
1.061e-02-4.55GATA3 (GATA binding protein 3)protein interactions262517731945450 QKI,TRPS1,NFIA
1.072e-02-4.54regulation of phospholipid effluxbiological processGO:1902994411820449 APOE
1.072e-02-4.54frontal suture morphogenesisbiological processGO:0060364411820449 GLI3
1.072e-02-4.54response to caloric restrictionbiological processGO:0061771411820449 APOE
1.072e-02-4.54positive regulation of cardiac muscle myoblast proliferationbiological processGO:0110024411820449 MEIS2
1.072e-02-4.54smoothened signaling pathway involved in dorsal/ventral neural tube patterningbiological processGO:0060831411820449 GLI3
1.072e-02-4.54ovarian cumulus expansionbiological processGO:0001550411820449 BMPR1B
1.072e-02-4.54NMDA glutamate receptor clusteringbiological processGO:0097114411820449 APOE
1.072e-02-4.54negative regulation of germ cell proliferationbiological processGO:1905937411820449 PTGDS
1.072e-02-4.54positive regulation of inclusion body assemblybiological processGO:0090261411820449 CLU
1.072e-02-4.54regulation of collagen catabolic processbiological processGO:0010710411820449 CST3
1.072e-02-4.54negative regulation of male germ cell proliferationbiological processGO:2000255411820449 PTGDS
1.072e-02-4.54protein localization to secretory granulebiological processGO:0033366411820449 CPE
1.072e-02-4.54positive regulation of phospholipid effluxbiological processGO:1902995411820449 APOE
1.072e-02-4.54short-chain fatty acid biosynthetic processbiological processGO:0051790411820449 ACSS1
1.076e-02-4.53CTF/NFI_DNA-bd-dominterpro domainsIPR020604411852150 NFIA
1.076e-02-4.53ApoA_Einterpro domainsIPR000074411852150 APOE
1.076e-02-4.53Alpha_catenininterpro domainsIPR001033411852150 CTNNA2
1.076e-02-4.53CTF/NFIinterpro domainsIPR000647411852150 NFIA
1.076e-02-4.53CTF/NFI_DNA-bd_CSinterpro domainsIPR019739411852150 NFIA
1.076e-02-4.53P5B-type_ATPaseinterpro domainsIPR047821411852150 ATP13A4
1.076e-02-4.53PKNOX/Meis_Ninterpro domainsIPR032453411852150 MEIS2
1.076e-02-4.53NHS-likeinterpro domainsIPR024845411852150 NHSL1
1.076e-02-4.53Desmoplakin_Spectrin-likeinterpro domainsIPR041573411852150 MACF1
1.076e-02-4.53AbLIM_anchorinterpro domainsIPR032402411852150 ABLIM1
1.076e-02-4.53Na/K-Atpase_Interactinginterpro domainsIPR008516411852150 NKAIN3
1.076e-02-4.53CTF/NFI_DNA-bd_Ninterpro domainsIPR019548411852150 NFIA
1.076e-02-4.53NDRGinterpro domainsIPR004142411852150 NDRG2
1.076e-02-4.53ACAS_Ninterpro domainsIPR032387411852150 ACSS1
1.076e-02-4.53P5A-ATPase_Ninterpro domainsIPR047819411852150 ATP13A4
1.076e-02-4.53FGF_rcpt_faminterpro domainsIPR016248411852150 FGFR3
1.076e-02-4.53PCN-like_spectrin-like_rptinterpro domainsIPR049538411852150 MACF1
1.077e-02-4.53MamL-1smart domainsSM0127531971735 MAML2
1.077e-02-4.53Sorbsmart domainsSM0045931971735 SORBS1
1.077e-02-4.53PLPsmart domainsSM0000231971735 GPM6A
1.082e-02-4.53skeletal system developmentbiological processGO:000150150051820449 TRPS1,BMPR1B,NFIA,FGFR3,GLI3
1.098e-02-4.51bone-tibia-Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumourCOSMIC cancer mutationsbone-tibia-Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour64961682849 ABLIM1,QKI,MACF1,ACSS1,PREX2,FGFR3
1.098e-02-4.51primitive_neuroectodermal_tumour-medulloblastomaCOSMIC cancer mutationsprimitive_neuroectodermal_tumour-medulloblastoma15350491682849 PITPNC1,MACF1,NDRG2,PTPRZ1,SPON1,SLC1A3,GLIS3,NTM,NPAS3,MEIS2,QKI,ATP13A4,SLC4A4,GPC5,CTNND2,APOE,PON2,DTNA,FGFR3,GLI3,PCDH9,AMZ2,NKAIN3,ARHGAP24,CDH20,PARD3B,PREX2,BMPR1B,AQP4,CPE,SPARCL1,LSAMP,RYR3,SLC1A2,MAML2,CLU,ABLIM1,CST3,COL5A3,FBXL7,ACSS1,NHSL1,PAMR1,MSI2,PTGDS,NFIA,TRPS1,GPM6A,SORBS1
1.101e-02-4.51endochondral bone morphogenesisbiological processGO:00603505921820449 BMPR1B,FGFR3
1.104e-02-4.51EZR (ezrin)protein interactions743052651945450 ABLIM1,ARHGAP24,MACF1,DTNA,SORBS1
1.107e-02-4.50inorganic molecular entity transmembrane transporter activitymolecular functionGO:001531871461809448 RYR3,SLC4A4,SLC1A3,AQP4,GPM6A,SLC1A2
1.118e-02-4.49parietal_lobeCOSMIC cancer mutationsparietal_lobe5521682849 FGFR3,QKI
1.119e-02-4.49ACAS_Npfam domainsPF16177411779550 ACSS1
1.119e-02-4.49Spectrin_2pfam domainsPF18373411779550 MACF1
1.119e-02-4.49AbLIM_anchorpfam domainsPF16182411779550 ABLIM1
1.119e-02-4.49Ndrpfam domainsPF03096411779550 NDRG2
1.119e-02-4.49Spectrin_3pfam domainsPF21019411779550 MACF1
1.119e-02-4.49Apolipoproteinpfam domainsPF01442411779550 APOE
1.119e-02-4.49Spectrin_4pfam domainsPF21020411779550 MACF1
1.119e-02-4.49NfI_DNAbd_pre-Npfam domainsPF10524411779550 NFIA
1.119e-02-4.49P5-ATPasepfam domainsPF12409411779550 ATP13A4
1.119e-02-4.49CTF_NFIpfam domainsPF00859411779550 NFIA
1.119e-02-4.49NKAINpfam domainsPF05640411779550 NKAIN3
1.119e-02-4.49NHSpfam domainsPF15273411779550 NHSL1
1.119e-02-4.49Meis_PKNOX_Npfam domainsPF16493411779550 MEIS2
1.121e-02-4.49YWHAB (tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein beta)protein interactions752996571945450 PARD3B,MACF1,ABLIM1,SORBS1,PITPNC1,NHSL1,FGFR3
1.126e-02-4.49monoatomic cation homeostasisbiological processGO:005508050551820449 SLC4A4,ATP13A4,APOE,RYR3,SLC1A3
1.128e-02-4.48regulation of cell sizebiological processGO:000836117331820449 APOE,MACF1,AQP4
1.137e-02-4.48regulation of glucose importbiological processGO:00463246021820449 SORBS1,SLC1A2
1.137e-02-4.48protein homotetramerizationbiological processGO:00512896021820449 AQP4,RYR3
1.143e-02-4.47human chr14q13.1chromosome locationhuman chr14q13.1612613450 NPAS3
1.143e-02-4.47human chr4q34.2chromosome locationhuman chr4q34.2612613450 GPM6A
1.144e-02-4.47MYELINPLPprints domainsPR0021431522720 GPM6A
1.144e-02-4.47RYANODINERprints domainsPR0079531522720 RYR3
1.144e-02-4.47PGNDSYNTHASEprints domainsPR0125431522720 PTGDS
1.144e-02-4.47PARAOXONASEprints domainsPR0178531522720 PON2
1.153e-02-4.46response to endogenous stimulusbiological processGO:0009719140291820449 SLC1A2,BMPR1B,NFIA,FGFR3,PTGDS,SLC1A3,SORBS1,MEIS2,RYR3
1.156e-02-4.46oligodendroglioma_Grade_IIICOSMIC cancer mutationsoligodendroglioma_Grade_III30341682849 FGFR3,PTPRZ1,MACF1,GLIS3
1.160e-02-4.46urinary_tract-bladder-other-normalCOSMIC cancer mutationsurinary_tract-bladder-other-normal411682849 FGFR3
1.160e-02-4.46invertedCOSMIC cancer mutationsinverted411682849 FGFR3
1.160e-02-4.46skin-face-malignant_melanoma-superficial_spreadingCOSMIC cancer mutationsskin-face-malignant_melanoma-superficial_spreading411682849 PREX2
1.160e-02-4.46skin-lower_leg-malignant_melanoma-nodularCOSMIC cancer mutationsskin-lower_leg-malignant_melanoma-nodular411682849 PREX2
1.160e-02-4.46urinary_tract-bladder-papilloma-invertedCOSMIC cancer mutationsurinary_tract-bladder-papilloma-inverted411682849 FGFR3
1.160e-02-4.46skin-benign_melanocytic_nevus-junctionalCOSMIC cancer mutationsskin-benign_melanocytic_nevus-junctional411682849 FGFR3
1.179e-02-4.44COL1A2 (collagen type I alpha 2 chain)protein interactions12786421945450 COL5A3,ARHGAP24
1.179e-02-4.44SYNC (syncoilin, intermediate filament protein)protein interactions814936421945450 MAML2,DTNA
1.179e-02-4.44VSX1 (visual system homeobox 1)protein interactions308136421945450 TRPS1,NFIA
1.179e-02-4.44EVA1C (eva-1 homolog C)protein interactions592716421945450 BMPR1B,PCDH9
1.184e-02-4.44cadherin bindingmolecular functionGO:004529633541809448 MACF1,CTNNA2,CTNND2,CDH20
1.190e-02-4.43biliary_tract-gallbladder-carcinoma-adenocarcinomaCOSMIC cancer mutationsbiliary_tract-gallbladder-carcinoma-adenocarcinoma2821151682849 SLC4A4,NHSL1,CTNND2,RYR3,PREX2,TRPS1,SPARCL1,CLU,MACF1,PITPNC1,COL5A3,NKAIN3,PCDH9,PTPRZ1,FGFR3
1.190e-02-4.43gallbladderCOSMIC cancer mutationsgallbladder2821151682849 NHSL1,SLC4A4,SPARCL1,TRPS1,CTNND2,RYR3,PREX2,PITPNC1,CLU,MACF1,NKAIN3,PCDH9,PTPRZ1,FGFR3,COL5A3
1.211e-02-4.41-gene3d domains1.20.58.1060411447044 MACF1
1.213e-02-4.41Transmembrane transport of small moleculesREACTOME pathwaysR-HSA-38255167761028530 AQP4,ATP13A4,SLC1A2,RYR3,SLC4A4,SLC1A3
1.218e-02-4.41monoatomic ion homeostasisbiological processGO:005080151551820449 ATP13A4,SLC4A4,SLC1A3,RYR3,APOE
1.230e-02-4.40KLF5 (KLF transcription factor 5)protein interactions68818731945450 TRPS1,CLU,NFIA
1.245e-02-4.39camera-type eye developmentbiological processGO:004301033541820449 BMPR1B,GPM6A,GLI3,NFIA
1.249e-02-4.38regulation of nitric oxide biosynthetic processbiological processGO:00454286321820449 APOE,CLU
1.250e-02-4.38MICB (MHC class I polypeptide-related sequence B)protein interactions42776621945450 APOE,CLU
1.250e-02-4.38MAML1 (mastermind like transcriptional coactivator 1)protein interactions97946621945450 NFIA,MAML2
1.250e-02-4.38ORM1 (orosomucoid 1)protein interactions50046621945450 CLU,PTGDS
1.250e-02-4.38KATNA1 (katanin catalytic subunit A1)protein interactions111046621945450 ARHGAP24,CLU
1.265e-02-4.37brain developmentbiological processGO:000742072461820449 SLC1A2,NDRG2,CTNNA2,MEIS2,GLI3,PCDH9
1.269e-02-4.37Arachidonic acid metabolismREACTOME pathwaysR-HSA-21427535921028530 PON2,PTGDS
1.276e-02-4.36neurofibrillary tanglecellular componentGO:0097418511910849 CLU
1.279e-02-4.36EPPIN (epididymal peptidase inhibitor)protein interactions57119511945450 CLU
1.279e-02-4.36Rhoj (ras homolog family member J)protein interactions80837511945450 BMPR1B
1.279e-02-4.36TRPM6 (transient receptor potential cation channel subfamily M member 6)protein interactions140803511945450 ARHGAP24
1.279e-02-4.36POU2F3 (POU class 2 homeobox 3)protein interactions25833511945450 ARHGAP24
1.279e-02-4.36ZNF93 (zinc finger protein 93)protein interactions81931511945450 ARHGAP24
1.279e-02-4.36Rab38 (RAB38, member RAS oncogene family)protein interactions72433511945450 BMPR1B
1.279e-02-4.36ZNF571 (zinc finger protein 571)protein interactions51276511945450 ARHGAP24
1.279e-02-4.36Rras2 (related RAS viral (r-ras) oncogene 2)protein interactions66922511945450 BMPR1B
1.279e-02-4.36Hk3 (hexokinase 3)protein interactions25060511945450 PTGDS
1.279e-02-4.36ADCYAP1R1 (ADCYAP receptor type I)protein interactions117511945450 CLU
1.279e-02-4.36Rab6b (RAB6B, member RAS oncogene family)protein interactions270192511945450 BMPR1B
1.279e-02-4.36Rhobtb1 (Rho-related BTB domain containing 1)protein interactions69288511945450 BMPR1B
1.279e-02-4.36TRH (thyrotropin releasing hormone)protein interactions7200511945450 CPE
1.279e-02-4.36Wwp2 (WW domain containing E3 ubiquitin protein ligase 2)protein interactions66894511945450 GLIS3
1.279e-02-4.36SLC10A3 (solute carrier family 10 member 3)protein interactions8273511945450 SORBS1
1.279e-02-4.36ZNF836 (zinc finger protein 836)protein interactions162962511945450 ARHGAP24
1.279e-02-4.36Cdk4 (cyclin dependent kinase 4)protein interactions12567511945450 BMPR1B
1.279e-02-4.36PTGER2 (prostaglandin E receptor 2)protein interactions5732511945450 PTGDS
1.287e-02-4.35cranial nerve developmentbiological processGO:00215456421820449 SLC1A3,GLI3
1.310e-02-4.34medullomyoblastomaCOSMIC cancer mutationsmedullomyoblastoma48551682849 PCDH9,ATP13A4,RYR3,SLC4A4,LSAMP
1.310e-02-4.34central_nervous_system-brain-primitive_neuroectodermal_tumour-medulloblastoma-medullomyoblastomaCOSMIC cancer mutationscentral_nervous_system-brain-primitive_neuroectodermal_tumour-medulloblastoma-medullomyoblastoma48551682849 RYR3,ATP13A4,SLC4A4,LSAMP,PCDH9
1.311e-02-4.33Signaling by BRAF and RAF fusionsREACTOME pathwaysR-HSA-68029526021028530 MACF1,QKI
1.317e-02-4.33upper_legCOSMIC cancer mutationsupper_leg88071682849 PAMR1,FGFR3,PCDH9,NFIA,PREX2,ACSS1,GLIS3
1.320e-02-4.33fibroblast growth factor receptor activitymolecular functionGO:0005007511809448 FGFR3
1.320e-02-4.33transforming growth factor beta receptor activity, type Imolecular functionGO:0005025511809448 BMPR1B
1.325e-02-4.32regulation of nitric oxide metabolic processbiological processGO:00801646521820449 APOE,CLU
1.327e-02-4.32L-amino acid transmembrane transporter activitymolecular functionGO:00151796621809448 SLC1A2,SLC1A3
1.332e-02-4.32human chr13q21.32chromosome locationhuman chr13q21.32712613450 PCDH9
1.332e-02-4.32human chr8q13.2chromosome locationhuman chr8q13.2712613450 PREX2
1.339e-02-4.31PHIP (pleckstrin homology domain interacting protein)protein interactions5502319331945450 CLU,GLI3,TRPS1
1.339e-02-4.31propionate metabolic processbiological processGO:0019541511820449 ACSS1
1.339e-02-4.31AMPA glutamate receptor clusteringbiological processGO:0097113511820449 APOE
1.339e-02-4.31positive regulation of dendritic spine maintenancebiological processGO:1902952511820449 APOE
1.339e-02-4.31central nervous system myelin maintenancebiological processGO:0032286511820449 CLU
1.339e-02-4.31glutamate receptor clusteringbiological processGO:0097688511820449 APOE
1.339e-02-4.31negative regulation of Rac protein signal transductionbiological processGO:0035021511820449 ARHGAP24
1.339e-02-4.31negative regulation of chondrocyte proliferationbiological processGO:1902731511820449 BMPR1B
1.339e-02-4.31chylomicron remnant clearancebiological processGO:0034382511820449 APOE
1.343e-02-4.31PI_transferinterpro domainsIPR001666511852150 PITPNC1
1.343e-02-4.31Vinculin/catenininterpro domainsIPR006077511852150 CTNNA2
1.343e-02-4.31Protocadherininterpro domainsIPR013585511852150 PCDH9
1.343e-02-4.31Na/HCO3_transptinterpro domainsIPR003024511852150 SLC4A4
1.343e-02-4.31P-type_TPase_Vinterpro domainsIPR006544511852150 ATP13A4
1.343e-02-4.31Follistatin/Osteonectin_EGFinterpro domainsIPR015369511852150 SPARCL1
1.343e-02-4.31BBP-likeinterpro domainsIPR045071511852150 QKI
1.356e-02-4.30armCOSMIC cancer mutationsarm133191682849 NTM,SLC4A4,MACF1,NPAS3,TRPS1,PARD3B,FGFR3,SORBS1,COL5A3
1.364e-02-4.29L-alpha-amino acid transmembrane transportbiological processGO:19024756621820449 SLC1A2,SLC1A3
1.367e-02-4.29neoplasmCOSMIC cancer mutationsneoplasm14787481682849 SPON1,SLC1A3,NDRG2,PTPRZ1,GLIS3,MACF1,GPC5,CTNND2,NTM,QKI,ATP13A4,SLC4A4,MEIS2,NPAS3,PCDH9,NKAIN3,AMZ2,GLI3,FGFR3,APOE,DTNA,PON2,PARD3B,PREX2,CDH20,ARHGAP24,BMPR1B,SPARCL1,RYR3,SLC1A2,LSAMP,AQP4,CPE,CST3,COL5A3,FBXL7,ACSS1,CLU,ABLIM1,MAML2,NFIA,TRPS1,GPM6A,SORBS1,NHSL1,PAMR1,MSI2,PTGDS
1.372e-02-4.29CTF_NFI_1prosite domainsPS00349411218642 NFIA
1.372e-02-4.29CTF_NFI_2prosite domainsPS51080411218642 NFIA
1.375e-02-4.29right_upper_lobeCOSMIC cancer mutationsright_upper_lobe10376381682849 CDH20,PAMR1,ARHGAP24,GPM6A,SORBS1,PREX2,NFIA,TRPS1,PARD3B,ABLIM1,DTNA,PON2,APOE,COL5A3,FBXL7,PCDH9,NKAIN3,FGFR3,GLI3,CPE,ATP13A4,SLC4A4,NPAS3,MEIS2,NTM,RYR3,CTNND2,SLC1A2,LSAMP,GPC5,MACF1,PITPNC1,BMPR1B,GLIS3,SPON1,SLC1A3,PTPRZ1,NDRG2
1.375e-02-4.29lung-right_upper_lobe-carcinoma-adenocarcinomaCOSMIC cancer mutationslung-right_upper_lobe-carcinoma-adenocarcinoma10376381682849 PON2,DTNA,ABLIM1,APOE,FBXL7,COL5A3,GLI3,FGFR3,NKAIN3,PCDH9,ARHGAP24,CDH20,PAMR1,PREX2,SORBS1,GPM6A,PARD3B,TRPS1,NFIA,MACF1,PITPNC1,GLIS3,BMPR1B,PTPRZ1,NDRG2,SLC1A3,SPON1,MEIS2,NPAS3,SLC4A4,CPE,ATP13A4,NTM,LSAMP,CTNND2,SLC1A2,RYR3,GPC5
1.397e-02-4.27FOLNpfam domainsPF09289511779550 SPARCL1
1.397e-02-4.27IP_transpfam domainsPF02121511779550 PITPNC1
1.397e-02-4.27Vinculinpfam domainsPF01044511779550 CTNNA2
1.397e-02-4.27Protocadherinpfam domainsPF08374511779550 PCDH9
1.399e-02-4.27PCDH20 (protocadherin 20)protein interactions648817021945450 PON2,CTNNA2
1.400e-02-4.27adenomaCOSMIC cancer mutationsadenoma2873151682849 APOE,MACF1,PTPRZ1,FGFR3,GLI3,PCDH9,ACSS1,COL5A3,BMPR1B,CDH20,NPAS3,GPC5,CTNND2,RYR3,GPM6A
1.403e-02-4.27monoatomic ion transmembrane transporter activitymolecular functionGO:001507575261809448 ATP13A4,SLC4A4,SLC1A3,RYR3,GPM6A,SLC1A2
1.404e-02-4.27cholesterol transportbiological processGO:00303016721820449 CLU,APOE
1.404e-02-4.27collagen bindingmolecular functionGO:00055186821809448 COL5A3,SPARCL1
1.410e-02-4.26protein processingbiological processGO:001648518831820449 SPON1,CPE,GLI3
1.418e-02-4.26hepatocellular_carcinomaCOSMIC cancer mutationshepatocellular_carcinoma14800481682849 ATP13A4,QKI,SLC4A4,MEIS2,NPAS3,NTM,CTNND2,GPC5,MACF1,PITPNC1,GLIS3,SPON1,SLC1A3,NDRG2,PTPRZ1,CDH20,ARHGAP24,PREX2,PARD3B,DTNA,PON2,APOE,PCDH9,AMZ2,NKAIN3,FGFR3,GLI3,AQP4,CPE,RYR3,SLC1A2,LSAMP,SPARCL1,BMPR1B,PTGDS,NHSL1,PAMR1,GPM6A,SORBS1,NFIA,TRPS1,CLU,ABLIM1,MAML2,COL5A3,ACSS1,FBXL7,CST3
1.418e-02-4.26liver-carcinoma-hepatocellular_carcinomaCOSMIC cancer mutationsliver-carcinoma-hepatocellular_carcinoma14800481682849 PTGDS,NHSL1,PAMR1,GPM6A,SORBS1,NFIA,TRPS1,MAML2,ABLIM1,CLU,COL5A3,ACSS1,FBXL7,CST3,CPE,AQP4,LSAMP,RYR3,SLC1A2,SPARCL1,BMPR1B,ARHGAP24,CDH20,PREX2,PARD3B,PON2,DTNA,APOE,FGFR3,GLI3,PCDH9,NKAIN3,AMZ2,MEIS2,NPAS3,QKI,ATP13A4,SLC4A4,NTM,CTNND2,GPC5,MACF1,PITPNC1,GLIS3,PTPRZ1,NDRG2,SPON1,SLC1A3
1.433e-02-4.25VAC14 (VAC14 component of PIKFYVE complex)protein interactions5569719831945450 QKI,ACSS1,ARHGAP24
1.448e-02-4.24skin-other-lichenoid_keratosisCOSMIC cancer mutationsskin-other-lichenoid_keratosis511682849 FGFR3
1.448e-02-4.24skin-face-other-nevus_sebaceousCOSMIC cancer mutationsskin-face-other-nevus_sebaceous511682849 FGFR3
1.448e-02-4.24skin-upper_leg-other-lichenoid_keratosisCOSMIC cancer mutationsskin-upper_leg-other-lichenoid_keratosis511682849 FGFR3
1.448e-02-4.24skin-shoulder-other-nevus_sebaceousCOSMIC cancer mutationsskin-shoulder-other-nevus_sebaceous511682849 FGFR3
1.448e-02-4.24skin-scalp-other-nevus_sebaceousCOSMIC cancer mutationsskin-scalp-other-nevus_sebaceous511682849 FGFR3
1.448e-02-4.24skin-chest-other-lichenoid_keratosisCOSMIC cancer mutationsskin-chest-other-lichenoid_keratosis511682849 FGFR3
1.448e-02-4.24syringocystadenoma_papilliferumCOSMIC cancer mutationssyringocystadenoma_papilliferum511682849 FGFR3
1.448e-02-4.24skin-breast-other-nevus_sebaceousCOSMIC cancer mutationsskin-breast-other-nevus_sebaceous511682849 FGFR3
1.448e-02-4.24skin-lower_back-other-lichenoid_keratosisCOSMIC cancer mutationsskin-lower_back-other-lichenoid_keratosis511682849 FGFR3
1.448e-02-4.24skin-lower_leg-other-lichenoid_keratosisCOSMIC cancer mutationsskin-lower_leg-other-lichenoid_keratosis511682849 FGFR3
1.448e-02-4.24skin-shoulder-other-lichenoid_keratosisCOSMIC cancer mutationsskin-shoulder-other-lichenoid_keratosis511682849 FGFR3
1.448e-02-4.24skin-adnexal_tumour-syringocystadenoma_papilliferumCOSMIC cancer mutationsskin-adnexal_tumour-syringocystadenoma_papilliferum511682849 FGFR3
1.448e-02-4.24skin-upper_arm-other-lichenoid_keratosisCOSMIC cancer mutationsskin-upper_arm-other-lichenoid_keratosis511682849 FGFR3
1.448e-02-4.24skin-forearm-other-seborrhoeic_keratosisCOSMIC cancer mutationsskin-forearm-other-seborrhoeic_keratosis511682849 FGFR3
1.448e-02-4.24skin-forearm-other-lichenoid_keratosisCOSMIC cancer mutationsskin-forearm-other-lichenoid_keratosis511682849 FGFR3
1.448e-02-4.24monoclonal_gammopathy_of_undetermined_significanceCOSMIC cancer mutationsmonoclonal_gammopathy_of_undetermined_significance511682849 FGFR3
1.448e-02-4.24skin-neck-other-lichenoid_keratosisCOSMIC cancer mutationsskin-neck-other-lichenoid_keratosis511682849 FGFR3
1.448e-02-4.24skin-breast-other-lichenoid_keratosisCOSMIC cancer mutationsskin-breast-other-lichenoid_keratosis511682849 FGFR3
1.448e-02-4.24skin-flank-other-lichenoid_keratosisCOSMIC cancer mutationsskin-flank-other-lichenoid_keratosis511682849 FGFR3
1.448e-02-4.24skin-lower_back-other-nevus_sebaceousCOSMIC cancer mutationsskin-lower_back-other-nevus_sebaceous511682849 FGFR3
1.448e-02-4.24haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-monoclonal_gammopathy_of_undetermined_significanceCOSMIC cancer mutationshaematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-monoclonal_gammopathy_of_undetermined_significance511682849 FGFR3
1.448e-02-4.24skin-neck-other-nevus_sebaceousCOSMIC cancer mutationsskin-neck-other-nevus_sebaceous511682849 FGFR3
1.448e-02-4.24skin-arm-other-seborrhoeic_keratosisCOSMIC cancer mutationsskin-arm-other-seborrhoeic_keratosis511682849 FGFR3
1.448e-02-4.24lichenoid_keratosisCOSMIC cancer mutationslichenoid_keratosis511682849 FGFR3
1.448e-02-4.24skin-ear-other-nevus_sebaceousCOSMIC cancer mutationsskin-ear-other-nevus_sebaceous511682849 FGFR3
1.448e-02-4.24skin-lower_leg-malignant_melanoma-superficial_spreadingCOSMIC cancer mutationsskin-lower_leg-malignant_melanoma-superficial_spreading511682849 PREX2
1.448e-02-4.24skin-upper_back-other-lichenoid_keratosisCOSMIC cancer mutationsskin-upper_back-other-lichenoid_keratosis511682849 FGFR3
1.448e-02-4.24skin-hand-other-lichenoid_keratosisCOSMIC cancer mutationsskin-hand-other-lichenoid_keratosis511682849 FGFR3
1.448e-02-4.24skin-hip-other-seborrhoeic_keratosisCOSMIC cancer mutationsskin-hip-other-seborrhoeic_keratosis511682849 FGFR3
1.448e-02-4.24skin-face-other-lichenoid_keratosisCOSMIC cancer mutationsskin-face-other-lichenoid_keratosis511682849 FGFR3
1.476e-02-4.22PPP3CC (protein phosphatase 3 catalytic subunit gamma)protein interactions55337221945450 BMPR1B,PARD3B
1.508e-02-4.19upper_backCOSMIC cancer mutationsupper_back32841682849 MACF1,GPC5,PARD3B,FGFR3
1.511e-02-4.19Apolipoproteingene3d domains1.20.120.20511447044 APOE
1.521e-02-4.19plasma membrane regioncellular componentGO:0098590127881910849 SLC4A4,GPM6A,AQP4,SORBS1,PARD3B,SLC1A3,MACF1,SLC1A2
1.522e-02-4.19ALPHACATENINprints domainsPR0080541522720 CTNNA2
1.526e-02-4.18negative regulation of smooth muscle cell proliferationbiological processGO:00486627021820449 NDRG2,APOE
1.527e-02-4.18Ethanol DegradationSMPDB pathwaysSMP00004497113693 ACSS1
1.529e-02-4.18multivesicular body, internal vesiclecellular componentGO:0097487611910849 APOE
1.532e-02-4.18FGF6 (fibroblast growth factor 6)protein interactions2251611945450 FGFR3
1.532e-02-4.18Map2k3 (mitogen-activated protein kinase kinase 3)protein interactions26397611945450 BMPR1B
1.532e-02-4.18PBP2 (Pbp2p)protein interactions852533611945450 QKI
1.532e-02-4.18LCAT (lecithin-cholesterol acyltransferase)protein interactions3931611945450 APOE
1.532e-02-4.18ZNF311 (zinc finger protein 311)protein interactions282890611945450 ARHGAP24
1.532e-02-4.18Itch (itchy, E3 ubiquitin protein ligase)protein interactions16396611945450 GLIS3
1.532e-02-4.18Tiam2 (T cell lymphoma invasion and metastasis 2)protein interactions24001611945450 DTNA
1.532e-02-4.18FGF23 (fibroblast growth factor 23)protein interactions8074611945450 FGFR3
1.532e-02-4.18FGF18 (fibroblast growth factor 18)protein interactions8817611945450 FGFR3
1.532e-02-4.18SLC12A5 (solute carrier family 12 member 5)protein interactions57468611945450 GPM6A
1.532e-02-4.18DRP2 (dystrophin related protein 2)protein interactions1821611945450 DTNA
1.532e-02-4.18Taok2 (TAO kinase 2)protein interactions381921611945450 CLU
1.532e-02-4.18GDF6 (growth differentiation factor 6)protein interactions392255611945450 BMPR1B
1.532e-02-4.18DAZ4 (deleted in azoospermia 4)protein interactions57135611945450 QKI
1.532e-02-4.18Rhod (ras homolog family member D)protein interactions11854611945450 BMPR1B
1.532e-02-4.18CYRIA (CYFIP related Rac1 interactor A)protein interactions81553611945450 GPM6A
1.532e-02-4.18Fancl (Fanconi anemia, complementation group L)protein interactions67030611945450 BMPR1B
1.532e-02-4.18Zbtb2 (zinc finger and BTB domain containing 2)protein interactions381990611945450 SORBS1
1.532e-02-4.18FXYD7 (FXYD domain containing ion transport regulator 7)protein interactions53822611945450 APOE
1.533e-02-4.18protein homooligomerizationbiological processGO:005126019431820449 AQP4,SLC1A2,RYR3
1.535e-02-4.18cell-cell adhesionbiological processGO:009860954651820449 PCDH9,CDH20,CTNNA2,SPARCL1,CTNND2
1.552e-02-4.17CASK (calcium/calmodulin dependent serine protein kinase)protein interactions857320431945450 PARD3B,DTNA,ABLIM1
1.554e-02-4.16bone developmentbiological processGO:006034819531820449 GLI3,FGFR3,BMPR1B
1.554e-02-4.16CACNA2D1 (calcium voltage-gated channel auxiliary subunit alpha2delta 1)protein interactions7817421945450 PON2,GPM6A
1.581e-02-4.15calcium-induced calcium release activitymolecular functionGO:0048763611809448 RYR3
1.581e-02-4.15arylesterase activitymolecular functionGO:0004064611809448 PON2
1.581e-02-4.15sodium:bicarbonate symporter activitymolecular functionGO:0008510611809448 SLC4A4
1.581e-02-4.15phosphatidylcholine-sterol O-acyltransferase activator activitymolecular functionGO:0060228611809448 APOE
1.590e-02-4.14animal organ morphogenesisbiological processGO:000988798871820449 FGFR3,CPE,GLI3,ABLIM1,CTNNA2,MEIS2,BMPR1B
1.600e-02-4.13otherCOSMIC cancer mutationsother14843481682849 MAML2,ABLIM1,CLU,COL5A3,ACSS1,FBXL7,CST3,PTGDS,NHSL1,MSI2,PAMR1,GPM6A,SORBS1,NFIA,TRPS1,BMPR1B,AQP4,CPE,LSAMP,RYR3,SLC1A2,SPARCL1,PON2,DTNA,APOE,FGFR3,GLI3,PCDH9,AMZ2,NKAIN3,ARHGAP24,CDH20,PREX2,PARD3B,MACF1,GLIS3,PTPRZ1,NDRG2,SPON1,SLC1A3,NPAS3,MEIS2,QKI,ATP13A4,SLC4A4,NTM,CTNND2,GPC5
1.604e-02-4.13regulation of low-density lipoprotein particle receptor catabolic processbiological processGO:0032803611820449 APOE
1.604e-02-4.13protein targeting to vacuole involved in autophagybiological processGO:0071211611820449 CLU
1.604e-02-4.13optic nerve morphogenesisbiological processGO:0021631611820449 GLI3
1.604e-02-4.13intracellular water homeostasisbiological processGO:0009992611820449 AQP4
1.604e-02-4.13gamma-aminobutyric acid biosynthetic processbiological processGO:0009449611820449 SLC1A3
1.604e-02-4.13negative regulation of extracellular matrix disassemblybiological processGO:0010716611820449 CST3
1.604e-02-4.13fused antrum stagebiological processGO:0048165611820449 BMPR1B
1.604e-02-4.13vascular associated smooth muscle cell proliferationbiological processGO:1990874611820449 NDRG2
1.604e-02-4.13mammary gland formationbiological processGO:0060592611820449 GLI3
1.604e-02-4.13triglyceride-rich lipoprotein particle clearancebiological processGO:0071830611820449 APOE
1.609e-02-4.13RyR/IP3R_RIH_dom_sfinterpro domainsIPR035910611852150 RYR3
1.609e-02-4.13Desmoplakin_SH3interpro domainsIPR041615611852150 MACF1
1.609e-02-4.13RIH_assoc-dominterpro domainsIPR013662611852150 RYR3
1.609e-02-4.13TSP1_spondin_dominterpro domainsIPR044004611852150 SPON1
1.609e-02-4.13Ryanodine_IP3_receptorinterpro domainsIPR015925611852150 RYR3
1.609e-02-4.13Glypican_CSinterpro domainsIPR019803611852150 GPC5
1.609e-02-4.13EF-hand_dom_typ1interpro domainsIPR015153611852150 DTNA
1.609e-02-4.13Glypicaninterpro domainsIPR001863611852150 GPC5
1.609e-02-4.13GAR_dominterpro domainsIPR003108611852150 MACF1
1.609e-02-4.13Ins145_P3_rcptinterpro domainsIPR014821611852150 RYR3
1.609e-02-4.13EF-hand_dom_typ2interpro domainsIPR015154611852150 DTNA
1.609e-02-4.13GAR_dom_sfinterpro domainsIPR036534611852150 MACF1
1.609e-02-4.13RIH_dominterpro domainsIPR000699611852150 RYR3
1.616e-02-4.13bone-femur-other-chondroblastomaCOSMIC cancer mutationsbone-femur-other-chondroblastoma18331682849 GPC5,PCDH9,RYR3
1.627e-02-4.12protein-containing complex bindingmolecular functionGO:00448771772101809448 COL5A3,MACF1,GLI3,PTPRZ1,CTNNA2,ABLIM1,NFIA,SPARCL1,CLU,APOE
1.629e-02-4.12MKRN2 (makorin ring finger protein 2)protein interactions2360938041945450 BMPR1B,FGFR3,GLI3,MACF1
1.633e-02-4.11RYK (receptor like tyrosine kinase)protein interactions625920831945450 PCDH9,CLU,CTNNA2
1.633e-02-4.11BCL2L1 (BCL2 like 1)protein interactions59820831945450 RYR3,CLU,ABLIM1
1.634e-02-4.11system processbiological processGO:00030082015111820449 DTNA,MEIS2,RYR3,ABLIM1,CTNNA2,AQP4,SLC4A4,SLC1A2,PTPRZ1,APOE,SLC1A3
1.635e-02-4.11MIR200A (microRNA 200a)protein interactions4069837621945450 QKI,MSI2
1.652e-02-4.10neuron fate commitmentbiological processGO:00486637321820449 NFIA,GLI3
1.652e-02-4.10peptide metabolic processbiological processGO:00065187321820449 SLC1A2,CPE
1.673e-02-4.09axonogenesisbiological processGO:000740936641820449 GLI3,PTPRZ1,BMPR1B,CTNNA2
1.674e-02-4.09EF-hand_3pfam domainsPF09069611779550 DTNA
1.674e-02-4.09EF-hand_2pfam domainsPF09068611779550 DTNA
1.674e-02-4.09RIH_assocpfam domainsPF08454611779550 RYR3
1.674e-02-4.09Plectinpfam domainsPF00681611779550 MACF1
1.674e-02-4.09SH3_10pfam domainsPF17902611779550 MACF1
1.674e-02-4.09Ins145_P3_recpfam domainsPF08709611779550 RYR3
1.674e-02-4.09Glypicanpfam domainsPF01153611779550 GPC5
1.674e-02-4.09GAS2pfam domainsPF02187611779550 MACF1
1.674e-02-4.09TSP1_spondinpfam domainsPF19028611779550 SPON1
1.674e-02-4.09RYDR_ITPRpfam domainsPF01365611779550 RYR3
1.675e-02-4.09skin-head_neck-malignant_melanoma-superficial_spreadingCOSMIC cancer mutationsskin-head_neck-malignant_melanoma-superficial_spreading92371682849 GLI3,PREX2,COL5A3,SORBS1,CTNND2,MACF1,ATP13A4
1.675e-02-4.09ABI1 (abl interactor 1)protein interactions1000621031945450 SORBS1,SLC1A3,NHSL1
1.695e-02-4.08positive regulation of gliogenesisbiological processGO:00140157421820449 PTPRZ1,QKI
1.695e-02-4.08sterol transportbiological processGO:00159187421820449 APOE,CLU
1.706e-02-4.07intracellular calcium ion homeostasisbiological processGO:000687420231820449 RYR3,APOE,ATP13A4
1.709e-02-4.07human chr4q22.3chromosome locationhuman chr4q22.3912613450 BMPR1B
1.710e-02-4.07head developmentbiological processGO:006032277461820449 NDRG2,SLC1A2,PCDH9,GLI3,MEIS2,CTNNA2
1.715e-02-4.07extremityCOSMIC cancer mutationsextremity1876111682849 ATP13A4,PITPNC1,CDH20,ACSS1,FBXL7,PREX2,COL5A3,RYR3,PTPRZ1,FGFR3,PCDH9
1.717e-02-4.06LRP8 (LDL receptor related protein 8)protein interactions78047821945450 CLU,APOE
1.717e-02-4.06MIR34C (microRNA 34c)protein interactions4070427821945450 QKI,MSI2
1.735e-02-4.05kidney-carcinoma-collecting_duct_carcinomaCOSMIC cancer mutationskidney-carcinoma-collecting_duct_carcinoma611682849 FGFR3
1.735e-02-4.05skin-in_situ_epithelial_neoplasm-actinic_keratosisCOSMIC cancer mutationsskin-in_situ_epithelial_neoplasm-actinic_keratosis611682849 FGFR3
1.735e-02-4.05skin-epidermal_nevusCOSMIC cancer mutationsskin-epidermal_nevus611682849 FGFR3
1.735e-02-4.05skin-arm-epidermal_nevusCOSMIC cancer mutationsskin-arm-epidermal_nevus611682849 FGFR3
1.735e-02-4.05skin-upper_leg-other-seborrhoeic_keratosisCOSMIC cancer mutationsskin-upper_leg-other-seborrhoeic_keratosis611682849 FGFR3
1.735e-02-4.05skin-benign_melanocytic_nevus-lentiginous_nevusCOSMIC cancer mutationsskin-benign_melanocytic_nevus-lentiginous_nevus611682849 FGFR3
1.735e-02-4.05skin-adnexal_tumour-trichoblastomaCOSMIC cancer mutationsskin-adnexal_tumour-trichoblastoma611682849 FGFR3
1.735e-02-4.05autonomic_ganglia-paraganglioma-benignCOSMIC cancer mutationsautonomic_ganglia-paraganglioma-benign611682849 NHSL1
1.735e-02-4.05skin-face-other-seborrhoeic_keratosisCOSMIC cancer mutationsskin-face-other-seborrhoeic_keratosis611682849 FGFR3
1.735e-02-4.05collecting_duct_carcinomaCOSMIC cancer mutationscollecting_duct_carcinoma611682849 FGFR3
1.735e-02-4.05lentiginous_nevusCOSMIC cancer mutationslentiginous_nevus611682849 FGFR3
1.735e-02-4.05skin-lower_back-other-seborrhoeic_keratosisCOSMIC cancer mutationsskin-lower_back-other-seborrhoeic_keratosis611682849 FGFR3
1.735e-02-4.05skin-in_situ_epithelial_neoplasm-Bowen_diseaseCOSMIC cancer mutationsskin-in_situ_epithelial_neoplasm-Bowen_disease611682849 FGFR3
1.735e-02-4.05skin-head_neck-epidermal_nevusCOSMIC cancer mutationsskin-head_neck-epidermal_nevus611682849 FGFR3
1.735e-02-4.05skin-trunk-epidermal_nevusCOSMIC cancer mutationsskin-trunk-epidermal_nevus611682849 FGFR3
1.735e-02-4.05skin-forearm-malignant_melanoma-superficial_spreadingCOSMIC cancer mutationsskin-forearm-malignant_melanoma-superficial_spreading611682849 PREX2
1.735e-02-4.05skin-abdomen-other-seborrhoeic_keratosisCOSMIC cancer mutationsskin-abdomen-other-seborrhoeic_keratosis611682849 FGFR3
1.735e-02-4.05skin-back-other-seborrhoeic_keratosisCOSMIC cancer mutationsskin-back-other-seborrhoeic_keratosis611682849 FGFR3
1.735e-02-4.05skin-flank-other-seborrhoeic_keratosisCOSMIC cancer mutationsskin-flank-other-seborrhoeic_keratosis611682849 FGFR3
1.735e-02-4.05skin-head_neck-malignant_melanomaCOSMIC cancer mutationsskin-head_neck-malignant_melanoma611682849 PREX2
1.735e-02-4.05skin-lower_leg-epidermal_nevusCOSMIC cancer mutationsskin-lower_leg-epidermal_nevus611682849 FGFR3
1.738e-02-4.05regulation of behaviorbiological processGO:00507957521820449 PTGDS,APOE
1.744e-02-4.05Bile Acid Indirect Signalling PathwaySMPDB pathwaysSMP00868518113693 FGFR3
1.759e-02-4.04PRDM1 (PR/SET domain 1)protein interactions6397921945450 NFIA,TRPS1
1.782e-02-4.03regulation of axon extensionbiological processGO:00305167621820449 APOE,MACF1
1.783e-02-4.03Ectoderm DifferentiationWikiPathwaysWP28581433531021 CTNND2,GLI3,CTNNA2
1.785e-02-4.03nitrogen compound transportbiological processGO:0071705150791820449 MACF1,APOE,SLC1A3,GLI3,ATP13A4,CPE,SLC1A2,QKI,CLU
1.786e-02-4.03Fbxo3 (F-box protein 3)protein interactions57443711945450 BMPR1B
1.786e-02-4.03SLC16A5 (solute carrier family 16 member 5)protein interactions9121711945450 PTPRZ1
1.786e-02-4.03RGMB (repulsive guidance molecule BMP co-receptor b)protein interactions285704711945450 BMPR1B
1.786e-02-4.03Smurf1 (SMAD specific E3 ubiquitin protein ligase 1)protein interactions75788711945450 GLIS3
1.786e-02-4.03Smad7 (SMAD family member 7)protein interactions17131711945450 BMPR1B
1.786e-02-4.03C8B (complement C8 beta chain)protein interactions732711945450 CLU
1.786e-02-4.03SOAT2 (sterol O-acyltransferase 2)protein interactions8435711945450 CLU
1.786e-02-4.03Pum2 (pumilio RNA-binding family member 2)protein interactions80913711945450 QKI
1.786e-02-4.03ZNF701 (zinc finger protein 701)protein interactions55762711945450 ARHGAP24
1.786e-02-4.03CYP4F8 (cytochrome P450 family 4 subfamily F member 8)protein interactions11283711945450 CLU
1.786e-02-4.03ZNF501 (zinc finger protein 501)protein interactions115560711945450 ARHGAP24
1.786e-02-4.03C7 (complement C7)protein interactions730711945450 CLU
1.786e-02-4.03FGF5 (fibroblast growth factor 5)protein interactions2250711945450 FGFR3
1.786e-02-4.03ABCC12 (ATP binding cassette subfamily C member 12)protein interactions94160711945450 NPAS3
1.786e-02-4.03Uhmk1 (U2AF homology motif (UHM) kinase 1)protein interactions16589711945450 BMPR1B
1.786e-02-4.03SASH3 (SAM and SH3 domain containing 3)protein interactions54440711945450 BMPR1B
1.801e-02-4.02MAP2 (microtubule associated protein 2)protein interactions41338021945450 GPM6A,APOE
1.811e-02-4.01Plakin repeatgene3d domains3.90.1290.10611447044 MACF1
1.811e-02-4.01Gas2-like domaingene3d domains3.30.920.20611447044 MACF1
1.811e-02-4.01IP3 receptor type 1 binding core, RIH domaingene3d domains1.25.10.30611447044 RYR3
1.827e-02-4.00BMP signaling pathwaybiological processGO:00305097721820449 NFIA,BMPR1B
1.837e-02-4.00oesophagus-middle_third-carcinoma-squamous_cell_carcinomaCOSMIC cancer mutationsoesophagus-middle_third-carcinoma-squamous_cell_carcinoma3531171682849 GPM6A,RYR3,CTNND2,PREX2,GPC5,SPARCL1,SLC4A4,NHSL1,PAMR1,COL5A3,SPON1,PCDH9,PTPRZ1,ABLIM1,MAML2,MACF1,PON2
1.840e-02-4.00actin filament bindingmolecular functionGO:005101521131809448 CTNNA2,MACF1,ABLIM1
1.843e-02-3.99LBD domain bindingmolecular functionGO:0050693711809448 SPON1
1.843e-02-3.99phosphatidic acid transfer activitymolecular functionGO:1990050711809448 PITPNC1
1.843e-02-3.99SOX17 (SRY-box transcription factor 17)protein interactions643218121945450 NFIA,TRPS1
1.843e-02-3.99ARNT2 (aryl hydrocarbon receptor nuclear translocator 2)protein interactions99158121945450 NPAS3,MEIS2
1.844e-02-3.99regulation of neurogenesisbiological processGO:005076737741820449 GLI3,QKI,PTPRZ1,MACF1
1.847e-02-3.99middle_thirdCOSMIC cancer mutationsmiddle_third3533171682849 COL5A3,PTPRZ1,SPON1,PCDH9,PON2,MAML2,MACF1,ABLIM1,PREX2,CTNND2,RYR3,GPM6A,SPARCL1,GPC5,SLC4A4,PAMR1,NHSL1
1.869e-02-3.98glial cell fate specificationbiological processGO:0021780711820449 NFIA
1.869e-02-3.98cellular response to magnesium ionbiological processGO:0071286711820449 RYR3
1.869e-02-3.98cell fate specification involved in pattern specificationbiological processGO:0060573711820449 GLI3
1.869e-02-3.98chaperone-mediated autophagybiological processGO:0061684711820449 CLU
1.869e-02-3.98ventral spinal cord interneuron specificationbiological processGO:0021521711820449 GLI3
1.869e-02-3.98forebrain dorsal/ventral pattern formationbiological processGO:0021798711820449 GLI3
1.869e-02-3.98regulation of male germ cell proliferationbiological processGO:2000254711820449 PTGDS
1.869e-02-3.98regulation of 3'-UTR-mediated mRNA stabilizationbiological processGO:1905868711820449 QKI
1.869e-02-3.98regulation of cardiac muscle myoblast proliferationbiological processGO:0110022711820449 MEIS2
1.869e-02-3.98regulation of oligodendrocyte progenitor proliferationbiological processGO:0070445711820449 PTPRZ1
1.869e-02-3.98negative regulation of ruffle assemblybiological processGO:1900028711820449 ARHGAP24
1.869e-02-3.98forebrain radial glial cell differentiationbiological processGO:0021861711820449 GLI3
1.869e-02-3.98high-density lipoprotein particle clearancebiological processGO:0034384711820449 APOE
1.869e-02-3.98negative regulation of Arp2/3 complex-mediated actin nucleationbiological processGO:0034316711820449 CTNNA2
1.869e-02-3.98positive regulation of receptor catabolic processbiological processGO:2000646711820449 APOE
1.869e-02-3.98positive regulation of transcription of Notch receptor targetbiological processGO:0007221711820449 MAML2
1.869e-02-3.98very-low-density lipoprotein particle remodelingbiological processGO:0034372711820449 APOE
1.869e-02-3.98hindgut morphogenesisbiological processGO:0007442711820449 GLI3
1.872e-02-3.98positive regulation of carbohydrate metabolic processbiological processGO:00459137821820449 SLC4A4,SORBS1
1.872e-02-3.98regulation of glucose transmembrane transportbiological processGO:00108277821820449 SLC1A2,SORBS1
1.872e-02-3.98dicarboxylic acid transportbiological processGO:00068357821820449 SLC1A3,SLC1A2
1.872e-02-3.98positive regulation of osteoblast differentiationbiological processGO:00456697821820449 BMPR1B,GLI3
1.875e-02-3.98Plakophilin/d_Catenininterpro domainsIPR028435711852150 CTNND2
1.875e-02-3.98SPARC/Testican_Ca-bd-dominterpro domainsIPR019577711852150 SPARCL1
1.875e-02-3.98Aquaporin_transptrinterpro domainsIPR034294711852150 AQP4
1.875e-02-3.98Plakin_repeat_sfinterpro domainsIPR035915711852150 MACF1
1.875e-02-3.98Alpha-catenin/vinculin-like_sfinterpro domainsIPR036723711852150 CTNNA2
1.875e-02-3.98Plectin_repeatinterpro domainsIPR001101711852150 MACF1
1.875e-02-3.98GS_dominterpro domainsIPR003605711852150 BMPR1B
1.886e-02-3.97GSC (goosecoid homeobox)protein interactions1452588221945450 TRPS1,NFIA
1.897e-02-3.96human chr9p24.2chromosome locationhuman chr9p24.21012613450 GLIS3
1.899e-02-3.96PITRANSFERprints domainsPR0039151522720 PITPNC1
1.899e-02-3.96NAHCO3TRSPRTprints domainsPR0123251522720 SLC4A4
1.914e-02-3.96central_nervous_system-brain-glioma-oligodendroglioma_Grade_IICOSMIC cancer mutationscentral_nervous_system-brain-glioma-oligodendroglioma_Grade_II7321682849 FGFR3,MACF1
1.917e-02-3.95regulation of glial cell differentiationbiological processGO:00456857921820449 PTPRZ1,QKI
1.922e-02-3.95prostateCOSMIC cancer mutationsprostate13883461682849 SPARCL1,LSAMP,RYR3,SLC1A2,CPE,AQP4,BMPR1B,NFIA,TRPS1,GPM6A,SORBS1,NHSL1,MSI2,PAMR1,COL5A3,FBXL7,ACSS1,MAML2,CLU,ABLIM1,GPC5,CTNND2,NTM,MEIS2,NPAS3,ATP13A4,QKI,SLC4A4,NDRG2,PTPRZ1,SPON1,SLC1A3,GLIS3,PITPNC1,MACF1,PARD3B,PREX2,ARHGAP24,CDH20,FGFR3,GLI3,PCDH9,NKAIN3,APOE,PON2,DTNA
1.930e-02-3.95PAX2 (paired box 2)protein interactions50768321945450 TRPS1,NFIA
1.930e-02-3.95DNM3 (dynamin 3)protein interactions260528321945450 GPM6A,FGFR3
1.930e-02-3.95TM2D3 (TM2 domain containing 3)protein interactions802138321945450 PON2,FGFR3
1.939e-02-3.94PSEN1 (presenilin 1)protein interactions566322231945450 CTNND2,DTNA,APOE
1.944e-02-3.94inorganic cation transmembrane transporter activitymolecular functionGO:002289058951809448 RYR3,SLC1A2,SLC1A3,SLC4A4,GPM6A
1.951e-02-3.94Oncogenic MAPK signalingREACTOME pathwaysR-HSA-68029577421028530 QKI,MACF1
1.951e-02-3.94SPARC_Ca_bdgpfam domainsPF10591711779550 SPARCL1
1.951e-02-3.94TGF_beta_GSpfam domainsPF08515711779550 BMPR1B
1.954e-02-3.94transmembrane receptor protein kinase activitymolecular functionGO:00191998121809448 FGFR3,BMPR1B
1.955e-02-3.93sensory organ developmentbiological processGO:000742358151820449 MEIS2,GPM6A,BMPR1B,NFIA,GLI3
1.964e-02-3.93oligodendroglioma_Grade_IICOSMIC cancer mutationsoligodendroglioma_Grade_II7421682849 MACF1,FGFR3
1.970e-02-3.93Bile secretionKEGG pathwaysko04976712716122 AQP4,SLC4A4
1.970e-02-3.93Bile secretionKEGG pathwayshsa04976712716122 SLC4A4,AQP4
1.977e-02-3.92chondrosarcomaCOSMIC cancer mutationschondrosarcoma118181682849 LSAMP,COL5A3,SPON1,NDRG2,PARD3B,SLC4A4,CPE,PON2
1.985e-02-3.92MAPRE3 (microtubule associated protein RP/EB family member 3)protein interactions2292422431945450 MACF1,ABLIM1,GPM6A
1.991e-02-3.92FGFR1 (fibroblast growth factor receptor 1)protein interactions226061151945450 ABLIM1,CLU,FGFR3,DTNA,NHSL1
2.004e-02-3.91somatodendritic compartmentcellular componentGO:003647784261910849 CTNND2,BMPR1B,GPM6A,APOE,SLC1A3,CLU
2.018e-02-3.90CCND3 (cyclin D3)protein interactions8968521945450 CLU,QKI
2.021e-02-3.90skin-shoulder-other-seborrhoeic_keratosisCOSMIC cancer mutationsskin-shoulder-other-seborrhoeic_keratosis711682849 FGFR3
2.021e-02-3.90urinary_tract-carcinoma-transitional_cell_carcinomaCOSMIC cancer mutationsurinary_tract-carcinoma-transitional_cell_carcinoma711682849 FGFR3
2.021e-02-3.90skin-adnexal_tumour-trichilemmomaCOSMIC cancer mutationsskin-adnexal_tumour-trichilemmoma711682849 FGFR3
2.021e-02-3.90skin-face-adnexal_tumour-malignant_adnexal_tumourCOSMIC cancer mutationsskin-face-adnexal_tumour-malignant_adnexal_tumour711682849 FGFR3
2.021e-02-3.90skin-chest-other-seborrhoeic_keratosisCOSMIC cancer mutationsskin-chest-other-seborrhoeic_keratosis711682849 FGFR3
2.021e-02-3.90skin-neck-other-seborrhoeic_keratosisCOSMIC cancer mutationsskin-neck-other-seborrhoeic_keratosis711682849 FGFR3
2.021e-02-3.90skin-upper_leg-malignant_melanoma-nodularCOSMIC cancer mutationsskin-upper_leg-malignant_melanoma-nodular711682849 PREX2
2.021e-02-3.90skin-benign_melanocytic_nevus-intradermalCOSMIC cancer mutationsskin-benign_melanocytic_nevus-intradermal711682849 FGFR3
2.021e-02-3.90skin-face-malignant_melanoma-nodularCOSMIC cancer mutationsskin-face-malignant_melanoma-nodular711682849 PREX2
2.021e-02-3.90nevus_sebaceousCOSMIC cancer mutationsnevus_sebaceous711682849 FGFR3
2.021e-02-3.90skin-other-nevus_sebaceousCOSMIC cancer mutationsskin-other-nevus_sebaceous711682849 FGFR3
2.021e-02-3.90trichilemmomaCOSMIC cancer mutationstrichilemmoma711682849 FGFR3
2.021e-02-3.90skin-benign_melanocytic_nevus-compoundCOSMIC cancer mutationsskin-benign_melanocytic_nevus-compound711682849 FGFR3
2.023e-02-3.90Adherens junctionKEGG pathwayshsa04520722716122 CTNNA2,SORBS1
2.023e-02-3.90Adherens junctionKEGG pathwaysko04520722716122 SORBS1,CTNNA2
2.023e-02-3.90monoatomic ion transmembrane transportbiological processGO:003422080461820449 GPM6A,RYR3,SLC1A2,SLC1A3,SLC4A4,ATP13A4
2.025e-02-3.90FGFR3b ligand binding and activationREACTOME pathwaysR-HSA-190371711028530 FGFR3
2.034e-02-3.90HFE-transferrin receptor complexcellular componentGO:1990712811910849 BMPR1B
2.034e-02-3.90spherical high-density lipoprotein particlecellular componentGO:0034366811910849 CLU
2.034e-02-3.90zonula adherenscellular componentGO:0005915811910849 SORBS1
2.038e-02-3.89Chmp2a (charged multivesicular body protein 2A)protein interactions68953811945450 CLU
2.038e-02-3.89Rps27a (ribosomal protein S27A)protein interactions78294811945450 BMPR1B
2.038e-02-3.89Rasd2 (RASD family, member 2)protein interactions75141811945450 BMPR1B
2.038e-02-3.89INSM1 (INSM transcriptional repressor 1)protein interactions3642811945450 SORBS1
2.038e-02-3.89Setdb1 (SET domain, bifurcated 1)protein interactions84505811945450 AMZ2
2.038e-02-3.89BMP15 (bone morphogenetic protein 15)protein interactions9210811945450 BMPR1B
2.038e-02-3.89SCT (secretin)protein interactions6343811945450 MEIS2
2.038e-02-3.89LHB (luteinizing hormone subunit beta)protein interactions3972811945450 NTM
2.038e-02-3.89ZNF236 (zinc finger protein 236)protein interactions7776811945450 ARHGAP24
2.038e-02-3.89PTGER1 (prostaglandin E receptor 1)protein interactions5731811945450 PTGDS
2.038e-02-3.89CCK (cholecystokinin)protein interactions885811945450 CPE
2.038e-02-3.89ZNF28 (zinc finger protein 28)protein interactions7576811945450 ARHGAP24
2.038e-02-3.89DEPP1 (DEPP autophagy regulator 1)protein interactions11067811945450 QKI
2.038e-02-3.89ZNF568 (zinc finger protein 568)protein interactions374900811945450 ARHGAP24
2.051e-02-3.89GLYPICANprosite domainsPS01207611218642 GPC5
2.051e-02-3.89GARprosite domainsPS51460611218642 MACF1
2.053e-02-3.89contractile actin filament bundlecellular componentGO:00975178621910849 ABLIM1,SORBS1
2.053e-02-3.89stress fibercellular componentGO:00017258621910849 SORBS1,ABLIM1
2.063e-02-3.88SYNJ1 (synaptojanin 1)protein interactions88678621945450 SORBS1,GPM6A
2.084e-02-3.87dendritecellular componentGO:003042562051910849 CTNND2,BMPR1B,CLU,GPM6A,APOE
2.101e-02-3.86EF_hand_dominterpro domainsIPR00204821831852150 RYR3,MACF1,SPARCL1
2.103e-02-3.86BMP receptor activitymolecular functionGO:0098821811809448 BMPR1B
2.103e-02-3.86glutamate bindingmolecular functionGO:0016595811809448 SLC1A3
2.105e-02-3.86glutamatergic synapsecellular componentGO:009897841241910849 SPARCL1,SLC1A2,GPM6A,APOE
2.108e-02-3.86MIR141 (microRNA 141)protein interactions4069338721945450 QKI,MSI2
2.108e-02-3.86Kctd5 (potassium channel tetramerisation domain containing 5)protein interactions692598721945450 TRPS1,SLC1A3
2.108e-02-3.86NHLH1 (nescient helix-loop-helix 1)protein interactions48078721945450 TRPS1,NFIA
2.110e-02-3.86dendritic treecellular componentGO:009744762251910849 CTNND2,BMPR1B,CLU,APOE,GPM6A
2.123e-02-3.85clear_cell_renal_cell_carcinomaCOSMIC cancer mutationsclear_cell_renal_cell_carcinoma13924461682849 DTNA,APOE,GLI3,FGFR3,NKAIN3,AMZ2,PCDH9,ARHGAP24,CDH20,PREX2,PARD3B,MACF1,PITPNC1,GLIS3,PTPRZ1,NDRG2,SLC1A3,SPON1,NPAS3,MEIS2,SLC4A4,QKI,ATP13A4,CTNND2,GPC5,MAML2,CLU,ABLIM1,FBXL7,ACSS1,COL5A3,PTGDS,MSI2,PAMR1,NHSL1,SORBS1,GPM6A,TRPS1,NFIA,BMPR1B,AQP4,CPE,LSAMP,SLC1A2,RYR3,SPARCL1
2.123e-02-3.85kidney-carcinoma-clear_cell_renal_cell_carcinomaCOSMIC cancer mutationskidney-carcinoma-clear_cell_renal_cell_carcinoma13924461682849 FBXL7,ACSS1,COL5A3,AMZ2,NKAIN3,PCDH9,FGFR3,GLI3,DTNA,ABLIM1,CLU,MAML2,APOE,SORBS1,GPM6A,PREX2,TRPS1,NFIA,PARD3B,PTGDS,MSI2,PAMR1,CDH20,NHSL1,ARHGAP24,BMPR1B,GLIS3,SLC1A3,SPON1,NDRG2,PTPRZ1,MACF1,PITPNC1,CTNND2,SLC1A2,RYR3,LSAMP,SPARCL1,GPC5,SLC4A4,ATP13A4,CPE,AQP4,QKI,MEIS2,NPAS3
2.126e-02-3.85femurCOSMIC cancer mutationsfemur119781682849 RYR3,PTPRZ1,GLI3,PCDH9,GPC5,SPON1,PON2,SLC4A4
2.134e-02-3.85regulation of Cdc42 protein signal transductionbiological processGO:0032489811820449 APOE
2.134e-02-3.85insulin processingbiological processGO:0030070811820449 CPE
2.134e-02-3.85regulation of germ cell proliferationbiological processGO:1905936811820449 PTGDS
2.134e-02-3.85triglyceride-rich lipoprotein particle remodelingbiological processGO:0034370811820449 APOE
2.134e-02-3.85hindgut developmentbiological processGO:0061525811820449 GLI3
2.134e-02-3.85gamma-aminobutyric acid metabolic processbiological processGO:0009448811820449 SLC1A3
2.134e-02-3.85positive regulation of CoA-transferase activitybiological processGO:1905920811820449 APOE
2.134e-02-3.85regulation of synapse structural plasticitybiological processGO:0051823811820449 CTNNA2
2.134e-02-3.85positive regulation of amyloid-beta clearancebiological processGO:1900223811820449 APOE
2.134e-02-3.85smooth muscle cell proliferationbiological processGO:0048659811820449 NDRG2
2.137e-02-3.85Diseases of signal transductionREACTOME pathwaysR-HSA-566320236941028530 MAML2,FGFR3,QKI,MACF1
2.140e-02-3.84Villin_headpiece_dom_sfinterpro domainsIPR036886811852150 ABLIM1
2.140e-02-3.84Villin_headpieceinterpro domainsIPR003128811852150 ABLIM1
2.140e-02-3.84Plakininterpro domainsIPR043197811852150 MACF1
2.142e-02-3.84GAS2smart domainsSM0024361971735 MACF1
2.151e-02-3.84L-amino acid transportbiological processGO:00158078421820449 SLC1A2,SLC1A3
2.153e-02-3.84HSPG2 (heparan sulfate proteoglycan 2)protein interactions33398821945450 GLI3,GPC5
2.175e-02-3.83CTSB (cathepsin B)protein interactions150823231945450 MSI2,CST3,APOE
2.199e-02-3.82SOX10 (SRY-box transcription factor 10)protein interactions66638921945450 NFIA,TRPS1
2.201e-02-3.82organic anion transportbiological processGO:001571139841820449 SLC4A4,SLC1A2,APOE,SLC1A3
2.226e-02-3.80VHPpfam domainsPF02209811779550 ABLIM1
2.229e-02-3.80cell-cell signalingbiological processGO:000726782261820449 SLC1A2,APOE,SLC1A3,DTNA,FGFR3,CPE
2.232e-02-3.80lung-left_upper_lobe-carcinoma-adenocarcinomaCOSMIC cancer mutationslung-left_upper_lobe-carcinoma-adenocarcinoma55651682849 CTNND2,SLC4A4,RYR3,FBXL7,TRPS1
2.247e-02-3.80Golgi apparatuscellular componentGO:0005794164591910849 CPE,PTGDS,FGFR3,APOE,GPC5,MACF1,NDRG2,CST3,CLU
2.262e-02-3.79left_upper_lobeCOSMIC cancer mutationsleft_upper_lobe55851682849 TRPS1,CTNND2,SLC4A4,RYR3,FBXL7
2.272e-02-3.78human chr11p15.2chromosome locationhuman chr11p15.21212613450 SPON1
2.272e-02-3.78human chr6q26chromosome locationhuman chr6q261212613450 QKI
2.274e-02-3.78CTSL (cathepsin L)protein interactions151423631945450 CST3,CLU,PON2
2.275e-02-3.78ACTIVIN2Rprints domainsPR0065361522720 BMPR1B
2.285e-02-3.78astrocyte end-footcellular componentGO:0097450911910849 AQP4
2.285e-02-3.78flotillin complexcellular componentGO:0016600911910849 SORBS1
2.290e-02-3.78CACNA2D3 (calcium voltage-gated channel auxiliary subunit alpha2delta 3)protein interactions55799911945450 APOE
2.290e-02-3.78LINC02582 (long intergenic non-protein coding RNA 2582)protein interactions100505817911945450 APOE
2.290e-02-3.78GUSBP1 (GUSB pseudogene 1)protein interactions728411911945450 FGFR3
2.290e-02-3.78Ywhag (tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide)protein interactions22628911945450 QKI
2.290e-02-3.78ZNF766 (zinc finger protein 766)protein interactions90321911945450 ARHGAP24
2.290e-02-3.78Tyw3 (tRNA-yW synthesizing protein 3 homolog (S. cerevisiae))protein interactions209584911945450 CTNNA2
2.290e-02-3.78VEPH1 (ventricular zone expressed PH domain containing 1)protein interactions79674911945450 BMPR1B
2.290e-02-3.78KCNV2 (potassium voltage-gated channel modifier subfamily V member 2)protein interactions169522911945450 AMZ2
2.290e-02-3.78NRXN2 (neurexin 2)protein interactions9379911945450 MACF1
2.292e-02-3.78DGUOK (deoxyguanosine kinase)protein interactions17169121945450 GPM6A,NTM
2.292e-02-3.78FOXI1 (forkhead box I1)protein interactions22999121945450 NFIA,TRPS1
2.296e-02-3.77dorsal/ventral pattern formationbiological processGO:00099538721820449 GLI3,BMPR1B
2.306e-02-3.77trichoblastomaCOSMIC cancer mutationstrichoblastoma811682849 FGFR3
2.306e-02-3.77cervical_intraepithelial_neoplasia_Grade_ICOSMIC cancer mutationscervical_intraepithelial_neoplasia_Grade_I811682849 FGFR3
2.306e-02-3.77central_nervous_system-chiasm-glioma-astrocytoma_Grade_ICOSMIC cancer mutationscentral_nervous_system-chiasm-glioma-astrocytoma_Grade_I811682849 QKI
2.306e-02-3.77skin-chest-malignant_melanoma-nodularCOSMIC cancer mutationsskin-chest-malignant_melanoma-nodular811682849 PREX2
2.306e-02-3.77actinic_keratosisCOSMIC cancer mutationsactinic_keratosis811682849 FGFR3
2.306e-02-3.77cervix-in_situ_neoplasm-cervical_intraepithelial_neoplasia_Grade_ICOSMIC cancer mutationscervix-in_situ_neoplasm-cervical_intraepithelial_neoplasia_Grade_I811682849 FGFR3
2.306e-02-3.77junctionalCOSMIC cancer mutationsjunctional811682849 FGFR3
2.306e-02-3.77urinary_tract-ureter-carcinoma-transitional_cell_carcinomaCOSMIC cancer mutationsurinary_tract-ureter-carcinoma-transitional_cell_carcinoma811682849 FGFR3
2.311e-02-3.77Release of Hh-Np from the secreting cellREACTOME pathwaysR-HSA-5362798811028530 GPC5
2.324e-02-3.76LCOR (ligand dependent nuclear receptor corepressor)protein interactions8445823831945450 SPARCL1,MACF1,CLU
2.325e-02-3.76forearmCOSMIC cancer mutationsforearm8121682849 PREX2,FGFR3
2.329e-02-3.76actomyosincellular componentGO:00426419221910849 ABLIM1,SORBS1
2.330e-02-3.76RNF43 (ring finger protein 43)protein interactions5489442441945450 QKI,MACF1,ABLIM1,GLI3
2.339e-02-3.76RLN1 (relaxin 1)protein interactions60139221945450 PON2,CPE
2.339e-02-3.76POTEI (POTE ankyrin domain family member I)protein interactions6532699221945450 FGFR3,DTNA
2.339e-02-3.76SOX9 (SRY-box transcription factor 9)protein interactions66629221945450 TRPS1,NFIA
2.341e-02-3.75skeletal system morphogenesisbiological processGO:004870522831820449 BMPR1B,FGFR3,GLI3
2.350e-02-3.75Validated targets of C-MYC transcriptional repressionPathway Interaction DBmyc_represspathway61222269 NDRG2,CLU
2.387e-02-3.74MIR19B2 (microRNA 19b-2)protein interactions4069819321945450 MSI2,QKI
2.387e-02-3.74ARHGEF6 (Rac/Cdc42 guanine nucleotide exchange factor 6)protein interactions94599321945450 ABLIM1,BMPR1B
2.387e-02-3.74DMRTB1 (DMRT like family B with proline rich C-terminal 1)protein interactions639489321945450 QKI,MSI2
2.388e-02-3.73GSprosite domainsPS51256711218642 BMPR1B
2.395e-02-3.73positive regulation of lipid biosynthetic processbiological processGO:00468898921820449 SORBS1,APOE
2.395e-02-3.73cell fate specificationbiological processGO:00017088921820449 GLI3,NFIA
2.397e-02-3.73microglial cell proliferationbiological processGO:0061518911820449 CLU
2.397e-02-3.73cranial suture morphogenesisbiological processGO:0060363911820449 GLI3
2.397e-02-3.73sterol catabolic processbiological processGO:0016127911820449 APOE
2.397e-02-3.73macrophage proliferationbiological processGO:0061517911820449 CLU
2.397e-02-3.73embryonic neurocranium morphogenesisbiological processGO:0048702911820449 GLI3
2.397e-02-3.73release of sequestered calcium ion into cytosol by sarcoplasmic reticulumbiological processGO:0014808911820449 RYR3
2.397e-02-3.73negative regulation of actin nucleationbiological processGO:0051126911820449 CTNNA2
2.397e-02-3.73cholesterol catabolic processbiological processGO:0006707911820449 APOE
2.397e-02-3.73cyclooxygenase pathwaybiological processGO:0019371911820449 PTGDS
2.397e-02-3.73hindbrain radial glia guided cell migrationbiological processGO:0021932911820449 CTNNA2
2.397e-02-3.73polyamine transmembrane transportbiological processGO:1902047911820449 ATP13A4
2.397e-02-3.73semicircular canal developmentbiological processGO:0060872911820449 GLI3
2.404e-02-3.73Activin_recpinterpro domainsIPR000472911852150 BMPR1B
2.404e-02-3.73Band3_cytoplasmic_dominterpro domainsIPR013769911852150 SLC4A4
2.404e-02-3.73Prot_inh_cystat_CSinterpro domainsIPR018073911852150 CST3
2.404e-02-3.73Fol_Ninterpro domainsIPR003645911852150 SPARCL1
2.407e-02-3.73Villin headpiece domaingene3d domains1.10.950.10811447044 ABLIM1
2.408e-02-3.73ion bindingmolecular functionGO:00431676007231809448 DTNA,TRPS1,PITPNC1,APOE,PAMR1,ABLIM1,CPE,ACSS1,FGFR3,PCDH9,GLIS3,SLC1A2,AMZ2,RYR3,PON2,PTGDS,SLC1A3,SPARCL1,ATP13A4,MACF1,GLI3,BMPR1B,SPON1
2.422e-02-3.72calcium ion homeostasisbiological processGO:005507423131820449 ATP13A4,RYR3,APOE
2.430e-02-3.72protein bindingmolecular functionGO:000551513983431809448 PITPNC1,AQP4,APOE,NFIA,TRPS1,DTNA,SORBS1,FGFR3,CTNND2,QKI,NDRG2,SLC1A3,CDH20,CLU,NTM,RYR3,PON2,MEIS2,BMPR1B,MACF1,LSAMP,FBXL7,NPAS3,COL5A3,CPE,ACSS1,ABLIM1,SLC1A2,GLIS3,PTGDS,SPARCL1,PTPRZ1,ARHGAP24,PARD3B,GLI3,CST3,SLC4A4,SPON1,MAML2,MSI2,CTNNA2,GPM6A,GPC5
2.435e-02-3.72TTR (transthyretin)protein interactions72769421945450 CTNND2,CLU
2.459e-02-3.71human chr5p15.1chromosome locationhuman chr5p15.11312613450 FBXL7
2.483e-02-3.70H2BC13 (H2B clustered histone 13)protein interactions83409521945450 ARHGAP24,GPM6A
2.495e-02-3.69PLECsmart domainsSM0025071971735 MACF1
2.495e-02-3.69GSsmart domainsSM0046771971735 BMPR1B
2.496e-02-3.69response to BMPbiological processGO:00717729121820449 BMPR1B,NFIA
2.496e-02-3.69cellular response to BMP stimulusbiological processGO:00717739121820449 BMPR1B,NFIA
2.501e-02-3.69Band_3_cytopfam domainsPF07565911779550 SLC4A4
2.501e-02-3.69Activin_recppfam domainsPF01064911779550 BMPR1B
2.519e-02-3.68chemical synaptic transmissionbiological processGO:000726841541820449 SLC1A3,SLC1A2,APOE,DTNA
2.519e-02-3.68anterograde trans-synaptic signalingbiological processGO:009891641541820449 SLC1A2,APOE,SLC1A3,DTNA
2.521e-02-3.68actin filament bundlecellular componentGO:00324329621910849 ABLIM1,SORBS1
2.528e-02-3.68Diseases of glycosylationREACTOME pathwaysR-HSA-37818658521028530 GPC5,SPON1
2.532e-02-3.68PDIA5 (protein disulfide isomerase family A member 5)protein interactions109549621945450 NTM,ARHGAP24
2.536e-02-3.67perineuronal netcellular componentGO:00725341011910849 PTPRZ1
2.541e-02-3.67Hsp90aa1 (heat shock protein 90, alpha (cytosolic), class A member 1)protein interactions155191011945450 QKI
2.541e-02-3.67GSG1 (germ cell associated 1)protein interactions834451011945450 PITPNC1
2.541e-02-3.67Smurf2 (SMAD specific E3 ubiquitin protein ligase 2)protein interactions663131011945450 GLIS3
2.541e-02-3.67ALKAL2 (ALK and LTK ligand 2)protein interactions2850161011945450 PON2
2.541e-02-3.67TSHZ1 (teashirt zinc finger homeobox 1)protein interactions101941011945450 MEIS2
2.541e-02-3.67CALB2 (calbindin 2)protein interactions7941011945450 GPM6A
2.541e-02-3.67ZNF852 (zinc finger protein 852)protein interactions2853461011945450 ARHGAP24
2.541e-02-3.67SLC8A2 (solute carrier family 8 member A2)protein interactions65431011945450 GPM6A
2.541e-02-3.67Mrpl13 (mitochondrial ribosomal protein L13)protein interactions685371011945450 QKI
2.541e-02-3.67Vbp1 (von Hippel-Lindau binding protein 1)protein interactions223271011945450 ABLIM1
2.541e-02-3.67ZNF606 (zinc finger protein 606)protein interactions800951011945450 ARHGAP24
2.541e-02-3.67SERPINB11 (serpin family B member 11)protein interactions897781011945450 CPE
2.541e-02-3.67P2rx7 (purinergic receptor P2X 7)protein interactions296651011945450 PTPRZ1
2.547e-02-3.67YWHAZ (tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein zeta)protein interactions7534113871945450 APOE,ABLIM1,MACF1,PITPNC1,PARD3B,SORBS1,NHSL1
2.548e-02-3.67protein tetramerizationbiological processGO:00512629221820449 AQP4,RYR3
2.581e-02-3.66BTG3 (BTG anti-proliferation factor 3)protein interactions109509721945450 SPARCL1,CLU
2.589e-02-3.65shoulderCOSMIC cancer mutationsshoulder38741682849 FGFR3,MACF1,PREX2,CPE
2.591e-02-3.65in_situ_epithelial_neoplasmCOSMIC cancer mutationsin_situ_epithelial_neoplasm911682849 FGFR3
2.591e-02-3.65compoundCOSMIC cancer mutationscompound911682849 FGFR3
2.591e-02-3.65ovary-low_malignant_potential_(borderline)_tumour-Brenner_tumourCOSMIC cancer mutationsovary-low_malignant_potential_(borderline)_tumour-Brenner_tumour911682849 FGFR3
2.591e-02-3.65epidermal_nevusCOSMIC cancer mutationsepidermal_nevus911682849 FGFR3
2.591e-02-3.65skin-chest-malignant_melanoma-superficial_spreadingCOSMIC cancer mutationsskin-chest-malignant_melanoma-superficial_spreading911682849 PREX2
2.591e-02-3.65Bowen_diseaseCOSMIC cancer mutationsBowen_disease911682849 FGFR3
2.591e-02-3.65skin-benign_melanocytic_nevus-congenitalCOSMIC cancer mutationsskin-benign_melanocytic_nevus-congenital911682849 FGFR3
2.591e-02-3.65skin-upper_leg-malignant_melanoma-superficial_spreadingCOSMIC cancer mutationsskin-upper_leg-malignant_melanoma-superficial_spreading911682849 PREX2
2.591e-02-3.65skin-other-seborrhoeic_keratosisCOSMIC cancer mutationsskin-other-seborrhoeic_keratosis911682849 FGFR3
2.596e-02-3.65Synthesis of 5-eicosatetraenoic acidsREACTOME pathwaysR-HSA-2142688911028530 PON2
2.596e-02-3.65Terminal pathway of complementREACTOME pathwaysR-HSA-166665911028530 CLU
2.599e-02-3.65regulation of extent of cell growthbiological processGO:00613879321820449 MACF1,APOE
2.612e-02-3.65transmembrane transporter activitymolecular functionGO:0022857111071809448 ATP13A4,SLC4A4,GPM6A,SLC1A3,SLC1A2,AQP4,RYR3
2.618e-02-3.64axon developmentbiological processGO:006156442041820449 CTNNA2,BMPR1B,PTPRZ1,GLI3
2.622e-02-3.64polyamine transmembrane transporter activitymolecular functionGO:00152031011809448 ATP13A4
2.622e-02-3.64phosphatidylinositol transfer activitymolecular functionGO:00085261011809448 PITPNC1
2.624e-02-3.64SYNE3 (spectrin repeat containing nuclear envelope family member 3)protein interactions16117644041945450 ABLIM1,MACF1,GLI3,SORBS1
2.631e-02-3.64FRS2 (fibroblast growth factor receptor substrate 2)protein interactions108189821945450 SORBS1,FGFR3
2.631e-02-3.64DNAAF2 (dynein axonemal assembly factor 2)protein interactions551729821945450 GPM6A,LSAMP
2.653e-02-3.63haematopoietic_neoplasmCOSMIC cancer mutationshaematopoietic_neoplasm11082391682849 MACF1,PTPRZ1,SPON1,SLC1A3,GLIS3,BMPR1B,NTM,MEIS2,NPAS3,QKI,ATP13A4,CPE,SLC4A4,GPC5,SPARCL1,LSAMP,RYR3,CTNND2,SLC1A2,MAML2,PON2,ABLIM1,DTNA,GLI3,FGFR3,PCDH9,NKAIN3,AMZ2,COL5A3,ACSS1,FBXL7,ARHGAP24,NHSL1,CDH20,MSI2,PAMR1,PARD3B,NFIA,PREX2
2.660e-02-3.63negative regulation of sterol biosynthetic processbiological processGO:01061191011820449 APOE
2.660e-02-3.63high-density lipoprotein particle assemblybiological processGO:00343801011820449 APOE
2.660e-02-3.63regulation of CoA-transferase activitybiological processGO:19059181011820449 APOE
2.660e-02-3.63regulation of bone developmentbiological processGO:19030101011820449 GLI3
2.660e-02-3.63release of sequestered calcium ion into cytosol by endoplasmic reticulumbiological processGO:19035141011820449 RYR3
2.660e-02-3.63negative regulation of cholesterol biosynthetic processbiological processGO:00455411011820449 APOE
2.660e-02-3.63spinal cord motor neuron cell fate specificationbiological processGO:00215201011820449 GLI3
2.660e-02-3.63nitric oxide-cGMP-mediated signalingbiological processGO:00380601011820449 APOE
2.660e-02-3.63establishment of centrosome localizationbiological processGO:00516601011820449 PARD3B
2.660e-02-3.63regulation of behavioral fear responsebiological processGO:20008221011820449 APOE
2.666e-02-3.62TGFBR1 (transforming growth factor beta receptor 1)protein interactions704625131945450 PREX2,CLU,BMPR1B
2.666e-02-3.62Ig_sub2interpro domainsIPR00359823931852150 LSAMP,FGFR3,NTM
2.668e-02-3.62MIR_motifinterpro domainsIPR0160931011852150 RYR3
2.668e-02-3.62MIP_CSinterpro domainsIPR0223571011852150 AQP4
2.668e-02-3.62PAS_fold_3interpro domainsIPR0136551011852150 NPAS3
2.668e-02-3.62MIR_dom_sfinterpro domainsIPR0363001011852150 RYR3
2.668e-02-3.62HCO3_transpt-like_TM_dominterpro domainsIPR0115311011852150 SLC4A4
2.668e-02-3.62HCO3_transpt_eukinterpro domainsIPR0030201011852150 SLC4A4
2.668e-02-3.62PTrfase/Anion_transptrinterpro domainsIPR0161521011852150 SLC4A4
2.668e-02-3.62Endochondral OssificationWikiPathwaysWP474652531021 GLI3,FGFR3
2.680e-02-3.62TPP1 (tripeptidyl peptidase 1)protein interactions12009921945450 PON2,APOE
2.698e-02-3.61developmental growthbiological processGO:004858942441820449 GLI3,FGFR3,BMPR1B,SLC1A2
2.698e-02-3.61growthbiological processGO:004000742441820449 BMPR1B,SLC1A2,GLI3,FGFR3
2.720e-02-3.60skin-mucosal-malignant_melanomaCOSMIC cancer mutationsskin-mucosal-malignant_melanoma2009111682849 PCDH9,FGFR3,BMPR1B,COL5A3,ABLIM1,SPARCL1,CTNND2,SORBS1,PREX2,ATP13A4,CPE
2.720e-02-3.60mucosalCOSMIC cancer mutationsmucosal2009111682849 CTNND2,BMPR1B,SORBS1,COL5A3,PREX2,PCDH9,SPARCL1,FGFR3,ABLIM1,ATP13A4,CPE
2.725e-02-3.60GATA_ZN_FINGER_1prosite domainsPS00344811218642 TRPS1
2.725e-02-3.60HPprosite domainsPS51089811218642 ABLIM1
2.731e-02-3.60SUFU (SUFU negative regulator of hedgehog signaling)protein interactions5168410021945450 GLI3,GLIS3
2.737e-02-3.60pancreas-other-adenomaCOSMIC cancer mutationspancreas-other-adenoma22431682849 CTNND2,BMPR1B,PCDH9
2.758e-02-3.59monoatomic cation transmembrane transportbiological processGO:009865563651820449 GPM6A,RYR3,SLC1A3,SLC4A4,ATP13A4
2.767e-02-3.59cellular component organizationbiological processGO:00160435636221820449 NFIA,AQP4,PREX2,SLC1A2,BMPR1B,GLI3,SORBS1,RYR3,PARD3B,GPM6A,CTNNA2,ABLIM1,SPARCL1,COL5A3,CLU,CDH20,PTPRZ1,MACF1,CTNND2,APOE,CST3,PITPNC1
2.771e-02-3.59actin bindingmolecular functionGO:000377943441809448 CTNNA2,ABLIM1,SORBS1,MACF1
2.775e-02-3.58PAS_3pfam domainsPF084471011779550 NPAS3
2.775e-02-3.58HCO3_cotransppfam domainsPF009551011779550 SLC4A4
2.775e-02-3.58MIRpfam domainsPF028151011779550 RYR3
2.776e-02-3.58DYNLL2 (dynein light chain LC8-type 2)protein interactions14073525531945450 TRPS1,NHSL1,NFIA
2.780e-02-3.58signalingbiological processGO:00230524968201820449 SLC1A3,MACF1,CTNND2,APOE,PITPNC1,CPE,CLU,ARHGAP24,SPARCL1,RYR3,SORBS1,GLI3,DTNA,MAML2,SLC1A2,BMPR1B,NDRG2,NFIA,FGFR3,PREX2
2.781e-02-3.58CLEC4A (C-type lectin domain family 4 member A)protein interactions5085610121945450 FGFR3,CTNNA2
2.786e-02-3.58perisynaptic extracellular matrixcellular componentGO:00989661111910849 PTPRZ1
2.792e-02-3.58CCDC17 (coiled-coil domain containing 17)protein interactions1494831111945450 FGFR3
2.792e-02-3.58MSRB1 (methionine sulfoxide reductase B1)protein interactions517341111945450 CLU
2.792e-02-3.58SYN3 (synapsin III)protein interactions82241111945450 GPM6A
2.792e-02-3.58NTS (neurotensin)protein interactions49221111945450 CPE
2.792e-02-3.58IL7 (interleukin 7)protein interactions35741111945450 QKI
2.792e-02-3.58Batf3 (basic leucine zipper transcription factor, ATF-like 3)protein interactions3813191111945450 MACF1
2.792e-02-3.58Gtf2e2 (general transcription factor II E, polypeptide 2 (beta subunit))protein interactions681531111945450 NHSL1
2.792e-02-3.58DAZ1 (deleted in azoospermia 1)protein interactions16171111945450 QKI
2.792e-02-3.58Wipi2 (WD repeat domain, phosphoinositide interacting 2)protein interactions747811111945450 MACF1
2.792e-02-3.58Cobll1 (Cobl-like 1)protein interactions3198761111945450 ABLIM1
2.792e-02-3.58PTGDR (prostaglandin D2 receptor)protein interactions57291111945450 PTGDS
2.792e-02-3.58ZNF726 (zinc finger protein 726)protein interactions7300871111945450 ARHGAP24
2.810e-02-3.57nerve developmentbiological processGO:00216759721820449 GLI3,SLC1A3
2.810e-02-3.57amino acid transmembrane transportbiological processGO:00033339721820449 SLC1A3,SLC1A2
2.832e-02-3.56human chr8q12.3chromosome locationhuman chr8q12.31512613450 NKAIN3
2.832e-02-3.56MIR7-1 (microRNA 7-1)protein interactions40704310221945450 MSI2,QKI
2.832e-02-3.56KRTAP6-1 (keratin associated protein 6-1)protein interactions33796610221945450 MEIS2,GLIS3
2.832e-02-3.56TMPRSS13 (transmembrane serine protease 13)protein interactions8400010221945450 SPON1,CPE
2.842e-02-3.56SFN (stratifin)protein interactions281067151945450 ABLIM1,MACF1,NFIA,SORBS1,PARD3B
2.842e-02-3.56trans-synaptic signalingbiological processGO:009953743141820449 DTNA,SLC1A3,SLC1A2,APOE
2.846e-02-3.56VHPsmart domainsSM0015381971735 ABLIM1
2.847e-02-3.56regulation of synapse organizationbiological processGO:005080724631820449 GPM6A,APOE,CTNNA2
2.875e-02-3.55kidney-carcinoma-renal_cell_carcinoma_unclassifiedCOSMIC cancer mutationskidney-carcinoma-renal_cell_carcinoma_unclassified1011682849 FGFR3
2.875e-02-3.55chiasmCOSMIC cancer mutationschiasm1011682849 QKI
2.875e-02-3.55cervical_intraepithelial_neoplasia_Grade_IIICOSMIC cancer mutationscervical_intraepithelial_neoplasia_Grade_III1011682849 FGFR3
2.875e-02-3.55lung-carcinoma-pleomorphic_carcinomaCOSMIC cancer mutationslung-carcinoma-pleomorphic_carcinoma1011682849 FGFR3
2.875e-02-3.55cervix-in_situ_neoplasm-cervical_intraepithelial_neoplasia_Grade_IIICOSMIC cancer mutationscervix-in_situ_neoplasm-cervical_intraepithelial_neoplasia_Grade_III1011682849 FGFR3
2.875e-02-3.55renal_cell_carcinoma_unclassifiedCOSMIC cancer mutationsrenal_cell_carcinoma_unclassified1011682849 FGFR3
2.875e-02-3.55skin-back-malignant_melanoma-nodularCOSMIC cancer mutationsskin-back-malignant_melanoma-nodular1011682849 PREX2
2.875e-02-3.55intradermalCOSMIC cancer mutationsintradermal1011682849 FGFR3
2.879e-02-3.55FLOT1 (flotillin 1)protein interactions1021145341945450 SORBS1,DTNA,ABLIM1,MACF1
2.880e-02-3.55Bicarbonate transportersREACTOME pathwaysR-HSA-4253811011028530 SLC4A4
2.880e-02-3.55Signaling by FGFR3 fusions in cancerREACTOME pathwaysR-HSA-88533341011028530 FGFR3
2.880e-02-3.55sulfur amino acid transmembrane transporter activitymolecular functionGO:00000991111809448 SLC1A2
2.884e-02-3.55RAB6B (RAB6B, member RAS oncogene family)protein interactions5156010321945450 GPM6A,BMPR1B
2.885e-02-3.55inorganic ion homeostasisbiological processGO:009877143341820449 RYR3,APOE,SLC1A3,ATP13A4
2.893e-02-3.54amino acid transmembrane transporter activitymolecular functionGO:001517110021809448 SLC1A3,SLC1A2
2.917e-02-3.53phospholipid transportbiological processGO:00159149921820449 APOE,PITPNC1
2.922e-02-3.53regulation of fear responsebiological processGO:19033651111820449 APOE
2.922e-02-3.53cell fate commitment involved in pattern specificationbiological processGO:00605811111820449 GLI3
2.922e-02-3.53antral ovarian follicle growthbiological processGO:00015471111820449 BMPR1B
2.922e-02-3.53thymocyte apoptotic processbiological processGO:00702421111820449 GLI3
2.922e-02-3.53regulation of receptor catabolic processbiological processGO:20006441111820449 APOE
2.922e-02-3.53intracellular mRNA localizationbiological processGO:00082981111820449 QKI
2.922e-02-3.53cellular response to caffeinebiological processGO:00713131111820449 RYR3
2.922e-02-3.53ventral spinal cord interneuron fate commitmentbiological processGO:00605791111820449 GLI3
2.922e-02-3.53polyamine transportbiological processGO:00158461111820449 ATP13A4
2.922e-02-3.53negative regulation of cholesterol metabolic processbiological processGO:00902061111820449 APOE
2.927e-02-3.53Post-translational modification: synthesis of GPI-anchored proteinsREACTOME pathwaysR-HSA-1631259221028530 NTM,LSAMP
2.931e-02-3.53Fib_collagen_Cinterpro domainsIPR0008851111852150 COL5A3
2.936e-02-3.53MFHAS1 (multifunctional ROCO family signaling regulator 1)protein interactions925810421945450 ARHGAP24,ABLIM1
2.975e-02-3.52amide bindingmolecular functionGO:003321825431809448 CST3,APOE,CLU
2.979e-02-3.51active transmembrane transporter activitymolecular functionGO:002280444441809448 SLC1A2,SLC1A3,SLC4A4,ATP13A4
2.988e-02-3.51ABCA2 (ATP binding cassette subfamily A member 2)protein interactions2010521945450 FGFR3,PON2
3.000e-02-3.51Helical hairpin bingene3d domains1.10.287.5701011447044 SLC4A4
3.022e-02-3.50GATAZNFINGERprints domainsPR0061981522720 TRPS1
3.022e-02-3.50LIPOCALINprints domainsPR0017981522720 PTGDS
3.027e-02-3.50regulation of synapse structure or activitybiological processGO:005080325231820449 CTNNA2,APOE,GPM6A
3.030e-02-3.50cell communicationbiological processGO:00071545010201820449 PREX2,NDRG2,FGFR3,NFIA,MAML2,BMPR1B,SLC1A2,DTNA,GLI3,SPARCL1,RYR3,SORBS1,CLU,ARHGAP24,CPE,SLC1A3,APOE,PITPNC1,CTNND2,MACF1
3.035e-02-3.49synapse-associated extracellular matrixcellular componentGO:00995351211910849 PTPRZ1
3.035e-02-3.49banded collagen fibrilcellular componentGO:00986431211910849 COL5A3
3.035e-02-3.49fibrillar collagen trimercellular componentGO:00055831211910849 COL5A3
3.040e-02-3.49USP30 (ubiquitin specific peptidase 30)protein interactions8474910621945450 FGFR3,QKI
3.042e-02-3.49UGT1A9 (UDP glucuronosyltransferase family 1 member A9)protein interactions546001211945450 PON2
3.042e-02-3.49ZNF235 (zinc finger protein 235)protein interactions93101211945450 ARHGAP24
3.042e-02-3.49MMP25 (matrix metallopeptidase 25)protein interactions643861211945450 CLU
3.042e-02-3.49BAMBI (BMP and activin membrane bound inhibitor)protein interactions258051211945450 BMPR1B
3.042e-02-3.49LOC102724560 (cystathionine beta-synthase like)protein interactions1027245601211945450 ARHGAP24
3.042e-02-3.49FAM222A (family with sequence similarity 222 member A)protein interactions849151211945450 MEIS2
3.042e-02-3.49CA4 (carbonic anhydrase 4)protein interactions7621211945450 SLC4A4
3.042e-02-3.49ART4 (ADP-ribosyltransferase 4 (inactive) (Dombrock blood group))protein interactions4201211945450 GPM6A
3.042e-02-3.49PROK2 (prokineticin 2)protein interactions606751211945450 CPE
3.042e-02-3.49ZNF91 (zinc finger protein 91)protein interactions76441211945450 ARHGAP24
3.042e-02-3.49upper_aerodigestive_tractCOSMIC cancer mutationsupper_aerodigestive_tract13181441682849 LSAMP,RYR3,SLC1A2,BMPR1B,PTGDS,NHSL1,PAMR1,MSI2,GPM6A,SORBS1,NFIA,TRPS1,MAML2,CLU,ABLIM1,COL5A3,FBXL7,ACSS1,CST3,NPAS3,QKI,ATP13A4,SLC4A4,NTM,CTNND2,GPC5,MACF1,PITPNC1,GLIS3,PTPRZ1,NDRG2,SPON1,SLC1A3,ARHGAP24,CDH20,PREX2,PARD3B,DTNA,APOE,GLI3,FGFR3,PCDH9,NKAIN3,AMZ2
3.049e-02-3.49COLFIpfam domainsPF014101111779550 COL5A3
3.060e-02-3.49CYSTATINprosite domainsPS00287911218642 CST3
3.066e-02-3.48Salivary secretionKEGG pathwayshsa04970902716122 CST3,RYR3
3.066e-02-3.48Salivary secretionKEGG pathwaysko04970902716122 RYR3,CST3
3.082e-02-3.48artery developmentbiological processGO:006084010221820449 APOE,GLI3
3.092e-02-3.48POMK (protein O-mannose kinase)protein interactions8419726631945450 CLU,PON2,BMPR1B
3.095e-02-3.48peptide bindingmolecular functionGO:004227725831809448 CLU,APOE,CST3
3.122e-02-3.47cellular response to endogenous stimulusbiological processGO:0071495113571820449 BMPR1B,SLC1A2,FGFR3,NFIA,RYR3,SORBS1,SLC1A3
3.122e-02-3.47Phase I biotransformations, non P450WikiPathwaysWP13681531021 PON2
3.138e-02-3.46regulation of neural precursor cell proliferationbiological processGO:200017710321820449 GLI3,PTPRZ1
3.147e-02-3.46BIN1 (bridging integrator 1)protein interactions27410821945450 GPM6A,CLU
3.147e-02-3.46FKBP1A (FKBP prolyl isomerase 1A)protein interactions228010821945450 RYR3,MSI2
3.147e-02-3.46EN1 (engrailed homeobox 1)protein interactions201910821945450 NFIA,TRPS1
3.147e-02-3.46GGT7 (gamma-glutamyltransferase 7)protein interactions268610821945450 ARHGAP24,NDRG2
3.147e-02-3.46PAX8 (paired box 8)protein interactions784910821945450 TRPS1,NFIA
3.149e-02-3.46PFN1 (profilin 1)protein interactions521646641945450 NHSL1,ABLIM1,ARHGAP24,MACF1
3.151e-02-3.46VCL (vinculin)protein interactions741426831945450 ARHGAP24,MACF1,SORBS1
3.151e-02-3.46protein complex oligomerizationbiological processGO:005125925631820449 AQP4,SLC1A2,RYR3
3.158e-02-3.46skin-hand-malignant_melanoma-acral_lentiginousCOSMIC cancer mutationsskin-hand-malignant_melanoma-acral_lentiginous1111682849 PREX2
3.158e-02-3.46congenitalCOSMIC cancer mutationscongenital1111682849 FGFR3
3.158e-02-3.46pleomorphic_carcinomaCOSMIC cancer mutationspleomorphic_carcinoma1111682849 FGFR3
3.158e-02-3.46oncocytomaCOSMIC cancer mutationsoncocytoma1111682849 FGFR3
3.158e-02-3.46skin-neck-carcinoma-basal_cell_carcinomaCOSMIC cancer mutationsskin-neck-carcinoma-basal_cell_carcinoma1111682849 FGFR3
3.158e-02-3.46kidney-other-oncocytomaCOSMIC cancer mutationskidney-other-oncocytoma1111682849 FGFR3
3.158e-02-3.46prostate-hyperplasiaCOSMIC cancer mutationsprostate-hyperplasia1111682849 FGFR3
3.158e-02-3.46skin-back-malignant_melanoma-superficial_spreadingCOSMIC cancer mutationsskin-back-malignant_melanoma-superficial_spreading1111682849 PREX2
3.158e-02-3.46skin-scalp-carcinoma-basal_cell_carcinomaCOSMIC cancer mutationsskin-scalp-carcinoma-basal_cell_carcinoma1111682849 FGFR3
3.158e-02-3.46seborrhoeic_keratosisCOSMIC cancer mutationsseborrhoeic_keratosis1111682849 FGFR3
3.184e-02-3.45neurotransmitter-gated ion channel clusteringbiological processGO:00725781211820449 APOE
3.184e-02-3.45negative thymic T cell selectionbiological processGO:00450601211820449 GLI3
3.184e-02-3.45microglia differentiationbiological processGO:00140041211820449 QKI
3.184e-02-3.45negative regulation of collagen metabolic processbiological processGO:00107131211820449 CST3
3.184e-02-3.45auditory behaviorbiological processGO:00312231211820449 SLC1A3
3.184e-02-3.45sulfur amino acid transportbiological processGO:00001011211820449 SLC1A2
3.184e-02-3.45positive regulation of extrinsic apoptotic signaling pathway via death domain receptorsbiological processGO:19020431211820449 BMPR1B
3.184e-02-3.45mammalian oogenesis stagebiological processGO:00226051211820449 BMPR1B
3.184e-02-3.45regulation of blood vessel remodelingbiological processGO:00603121211820449 CST3
3.193e-02-3.44Lipocalininterpro domainsIPR0023451211852150 PTGDS
3.193e-02-3.44MAD_homology1_Dwarfin-typeinterpro domainsIPR0036191211852150 NFIA
3.193e-02-3.44Lipocalin_CSinterpro domainsIPR0222721211852150 PTGDS
3.193e-02-3.44TGFB_receptorinterpro domainsIPR0003331211852150 BMPR1B
3.197e-02-3.44FOLNsmart domainsSM0027491971735 SPARCL1
3.200e-02-3.44MIR34B (microRNA 34b)protein interactions40704110921945450 MSI2,QKI
3.213e-02-3.44ATXN1 (ataxin 1)protein interactions631046941945450 PTGDS,QKI,NFIA,CST3
3.251e-02-3.43neural precursor cell proliferationbiological processGO:006135110521820449 GLI3,NFIA
3.254e-02-3.43SCARB1 (scavenger receptor class B member 1)protein interactions94911021945450 PON2,APOE
3.254e-02-3.43LZTR1 (leucine zipper like post translational regulator 1)protein interactions821611021945450 PARD3B,BMPR1B
3.275e-02-3.42regulation of plasma membrane bounded cell projection organizationbiological processGO:012003566651820449 ARHGAP24,GPM6A,APOE,MACF1,CTNNA2
3.276e-02-3.42prostate-carcinoma-adenocarcinomaCOSMIC cancer mutationsprostate-carcinoma-adenocarcinoma12379421682849 SLC1A3,SPON1,NDRG2,PTPRZ1,BMPR1B,GLIS3,PITPNC1,MACF1,SPARCL1,GPC5,SLC1A2,CTNND2,RYR3,LSAMP,NTM,CPE,ATP13A4,AQP4,QKI,NPAS3,MEIS2,NKAIN3,PCDH9,GLI3,FGFR3,FBXL7,ACSS1,COL5A3,CLU,ABLIM1,PON2,MAML2,TRPS1,NFIA,PARD3B,SORBS1,GPM6A,PREX2,CDH20,PAMR1,NHSL1,ARHGAP24
3.281e-02-3.42distal axoncellular componentGO:015003427331910849 NDRG2,PCDH9,GPM6A
3.284e-02-3.42chylomicroncellular componentGO:00426271311910849 APOE
3.291e-02-3.41ANKH (ANKH inorganic pyrophosphate transport regulator)protein interactions561721311945450 APOE
3.291e-02-3.41RAB3C (RAB3C, member RAS oncogene family)protein interactions1158271311945450 GPM6A
3.291e-02-3.41ST3GAL5 (ST3 beta-galactoside alpha-2,3-sialyltransferase 5)protein interactions88691311945450 PON2
3.291e-02-3.41Pias1 (protein inhibitor of activated STAT 1)protein interactions564691311945450 GLI3
3.291e-02-3.41TBCC (tubulin folding cofactor C)protein interactions69031311945450 NTM
3.291e-02-3.41MAB21L1 (mab-21 like 1)protein interactions40811311945450 MEIS2
3.291e-02-3.41Rbm47 (RNA binding motif protein 47)protein interactions2459451311945450 QKI
3.291e-02-3.41CCN5 (cellular communication network factor 5)protein interactions88391311945450 AMZ2
3.291e-02-3.41ZNF718 (zinc finger protein 718)protein interactions2554031311945450 ARHGAP24
3.291e-02-3.41PCDHA2 (protocadherin alpha 2)protein interactions561461311945450 NFIA
3.296e-02-3.41Carboxypeptidase-like, regulatory domaingene3d domains2.60.40.11201111447044 CPE
3.302e-02-3.41endoplasmic reticulumcellular componentGO:00057832051101910849 SPON1,ATP13A4,COL5A3,CLU,CST3,RYR3,SPARCL1,PTGDS,APOE,FGFR3
3.307e-02-3.41pigmentationbiological processGO:004347310621820449 GLI3,APOE
3.309e-02-3.41cell-cell adhesion via plasma-membrane adhesion moleculesbiological processGO:009874226131820449 PCDH9,CDH20,SPARCL1
3.321e-02-3.40CarboxypepD_regpfam domainsPF136201211779550 CPE
3.321e-02-3.40MH1pfam domainsPF031651211779550 NFIA
3.330e-02-3.40Hedgehog signalingKEGG pathwayshsa_M00678111716122 GLI3
3.330e-02-3.40Hedgehog signalingKEGG pathwaysM00678111716122 GLI3
3.363e-02-3.39TBR1 (T-box brain transcription factor 1)protein interactions1071611221945450 NFIA,TRPS1
3.363e-02-3.39TSC22D4 (TSC22 domain family member 4)protein interactions8162811221945450 ABLIM1,CLU
3.363e-02-3.39CEP170P1 (centrosomal protein 170 pseudogene 1)protein interactions64545511221945450 TRPS1,MACF1
3.387e-02-3.39skin-arm-malignant_melanomaCOSMIC cancer mutationsskin-arm-malignant_melanoma130881682849 SORBS1,COL5A3,TRPS1,PARD3B,SLC4A4,MACF1,NPAS3,NTM
3.389e-02-3.38human chr7q31.32chromosome locationhuman chr7q31.321812613450 PTPRZ1
3.389e-02-3.38human chr18q21.33chromosome locationhuman chr18q21.331812613450 CDH20
3.394e-02-3.38NAKATPASEprints domainsPR0012191522720 ATP13A4
3.395e-02-3.38MIPprosite domainsPS002211011218642 AQP4
3.395e-02-3.38MIRprosite domainsPS509191011218642 RYR3
3.395e-02-3.38transforming growth factor beta receptor activitymolecular functionGO:00050241311809448 BMPR1B
3.395e-02-3.38monoatomic cation:bicarbonate symporter activitymolecular functionGO:01404101311809448 SLC4A4
3.396e-02-3.38regulation of nervous system developmentbiological processGO:005196045641820449 MACF1,GLI3,PTPRZ1,QKI
3.400e-02-3.38calcium ion bindingmolecular functionGO:000550968351809448 MACF1,RYR3,PAMR1,PCDH9,SPARCL1
3.405e-02-3.38NR3C1 (nuclear receptor subfamily 3 group C member 1)protein interactions290895061945450 PON2,ATP13A4,NFIA,TRPS1,SLC1A3,CTNND2
3.408e-02-3.38organic anion transmembrane transporter activitymolecular functionGO:000851426831809448 SLC1A2,SLC1A3,SLC4A4
3.440e-02-3.37skin-face-carcinoma-basal_cell_carcinomaCOSMIC cancer mutationsskin-face-carcinoma-basal_cell_carcinoma1211682849 FGFR3
3.440e-02-3.37skin-benign_melanocytic_nevusCOSMIC cancer mutationsskin-benign_melanocytic_nevus1211682849 FGFR3
3.440e-02-3.37cervix-carcinoma-mixed_adenosquamous_carcinomaCOSMIC cancer mutationscervix-carcinoma-mixed_adenosquamous_carcinoma1211682849 FGFR3
3.440e-02-3.37central_nervous_system-fourth_ventricle-glioma-astrocytoma_Grade_ICOSMIC cancer mutationscentral_nervous_system-fourth_ventricle-glioma-astrocytoma_Grade_I1211682849 QKI
3.440e-02-3.37skin-abdomen-malignant_melanoma-nodularCOSMIC cancer mutationsskin-abdomen-malignant_melanoma-nodular1211682849 PREX2
3.443e-02-3.37positive regulation of cell developmentbiological processGO:001072045841820449 GLI3,PTPRZ1,QKI,MACF1
3.444e-02-3.37ventral spinal cord interneuron differentiationbiological processGO:00215141311820449 GLI3
3.444e-02-3.37prepulse inhibitionbiological processGO:00601341311820449 CTNNA2
3.444e-02-3.37negative T cell selectionbiological processGO:00433831311820449 GLI3
3.444e-02-3.37regulation of dendritic spine maintenancebiological processGO:19029501311820449 APOE
3.444e-02-3.37glial cell fate commitmentbiological processGO:00217811311820449 NFIA
3.444e-02-3.37phospholipid effluxbiological processGO:00337001311820449 APOE
3.446e-02-3.37FGFR3 mutant receptor activationREACTOME pathwaysR-HSA-20335141211028530 FGFR3
3.446e-02-3.37Signaling by activated point mutants of FGFR3REACTOME pathwaysR-HSA-18391301211028530 FGFR3
3.446e-02-3.37Defective EXT2 causes exostoses 2REACTOME pathwaysR-HSA-36562371211028530 GPC5
3.446e-02-3.37Defective EXT1 causes exostoses 1, TRPS2 and CHDSREACTOME pathwaysR-HSA-36562531211028530 GPC5
3.446e-02-3.37Ethanol oxidationREACTOME pathwaysR-HSA-713841211028530 ACSS1
3.456e-02-3.37animal organ developmentbiological processGO:00485132846131820449 CPE,COL5A3,GPM6A,MEIS2,CTNNA2,ABLIM1,PCDH9,GLI3,BMPR1B,SLC1A2,NFIA,FGFR3,NDRG2
3.459e-02-3.36small molecule bindingmolecular functionGO:00360946197231809448 PTGDS,SLC1A3,SPARCL1,ATP13A4,RYR3,PON2,BMPR1B,GLI3,MACF1,SPON1,PITPNC1,APOE,TRPS1,DTNA,PAMR1,ACSS1,CPE,FGFR3,PCDH9,ABLIM1,SLC1A2,AMZ2,GLIS3
3.466e-02-3.36synaptic signalingbiological processGO:009953645941820449 SLC1A2,APOE,SLC1A3,DTNA
3.466e-02-3.36small molecule biosynthetic processbiological processGO:004428345941820449 PTGDS,SLC1A3,ACSS1,QKI
3.474e-02-3.36ORF3b (ORF3b protein)protein interactions148967011421945450 PCDH9,MACF1
3.475e-02-3.36Visual phototransductionREACTOME pathwaysR-HSA-218733810121028530 GPC5,APOE
3.481e-02-3.36postsynapse organizationbiological processGO:009917310921820449 CTNND2,APOE
3.481e-02-3.36long-chain fatty acid metabolic processbiological processGO:000167610921820449 QKI,PTGDS
3.481e-02-3.36DiseaseREACTOME pathwaysR-HSA-164368585861028530 MAML2,FGFR3,MACF1,SPON1,QKI,GPC5
3.500e-02-3.35Cadherin_CSinterpro domainsIPR02089410921852150 PCDH9,CDH20
3.506e-02-3.35chemical homeostasisbiological processGO:004887891461820449 AQP4,SLC4A4,ATP13A4,SLC1A3,APOE,RYR3
3.506e-02-3.35Tgif disruption of Shh signalingWikiPathwaysWP367491531021 GLI3
3.530e-02-3.34SULF2 (sulfatase 2)protein interactions5595911521945450 SPON1,PON2
3.530e-02-3.34TBXT (T-box transcription factor T)protein interactions686211521945450 TRPS1,NFIA
3.532e-02-3.34chromaffin granulecellular componentGO:00425831411910849 CLU
3.540e-02-3.34Stag2 (STAG2 cohesin complex component)protein interactions208431411945450 CLU
3.540e-02-3.34RHEBL1 (RHEB like 1)protein interactions1212681411945450 BMPR1B
3.540e-02-3.34FGF7 (fibroblast growth factor 7)protein interactions22521411945450 FGFR3
3.540e-02-3.34Aifm1 (apoptosis-inducing factor, mitochondrion-associated 1)protein interactions269261411945450 CLU
3.540e-02-3.34KRTAP22-1 (keratin associated protein 22-1)protein interactions3379791411945450 MEIS2
3.540e-02-3.34SLC1A2 (solute carrier family 1 member 2)protein interactions65061411945450 SLC1A2
3.540e-02-3.34MB (myoglobin)protein interactions41511411945450 MAML2
3.540e-02-3.34Asap1 (ArfGAP with SH3 domain, ankyrin repeat and PH domain1)protein interactions131961411945450 MACF1
3.540e-02-3.34IFNA8 (interferon alpha 8)protein interactions34451411945450 APOE
3.540e-02-3.34Nedd4 (neural precursor cell expressed, developmentally down-regulated 4)protein interactions179991411945450 GLIS3
3.546e-02-3.34MIRsmart domainsSM00472101971735 RYR3
3.558e-02-3.34LYN (LYN proto-oncogene, Src family tyrosine kinase)protein interactions406771351945450 ABLIM1,MACF1,DTNA,MSI2,SLC1A3
3.559e-02-3.34side of membranecellular componentGO:009855271551910849 AQP4,LSAMP,DTNA,GPC5,NTM
3.570e-02-3.33blood microparticlecellular componentGO:007256211621910849 CLU,APOE
3.573e-02-3.33positive regulation of cellular metabolic processbiological processGO:00313253164141820449 MEIS2,SORBS1,NPAS3,GLI3,SPON1,BMPR1B,MAML2,GLIS3,SLC4A4,FGFR3,NFIA,QKI,APOE,CLU
3.574e-02-3.33human chr6q24.1chromosome locationhuman chr6q24.11912613450 NHSL1
3.574e-02-3.33human chr5p15.2chromosome locationhuman chr5p15.21912613450 CTNND2
3.574e-02-3.33human chr11q25chromosome locationhuman chr11q251912613450 NTM
3.586e-02-3.33RBBP8 (RB binding protein 8, endonuclease)protein interactions593211621945450 CLU,CTNNA2
3.586e-02-3.33SKIL (SKI like proto-oncogene)protein interactions649811621945450 SPARCL1,MACF1
3.590e-02-3.33Alpha-catenin/vinculin-likegene3d domains1.20.120.2301211447044 CTNNA2
3.593e-02-3.33regulation of cell projection organizationbiological processGO:003134468351820449 ARHGAP24,CTNNA2,GPM6A,APOE,MACF1
3.593e-02-3.33skin-upper_leg-malignant_melanomaCOSMIC cancer mutationsskin-upper_leg-malignant_melanoma85061682849 PREX2,ACSS1,GLIS3,PCDH9,NFIA,PAMR1
3.619e-02-3.32cell migrationbiological processGO:001647792161820449 GPM6A,GPC5,CTNNA2,CDH20,GLI3,ARHGAP24
3.642e-02-3.31ELK3 (ETS transcription factor ELK3)protein interactions200411721945450 TRPS1,NFIA
3.642e-02-3.31ZMYND19 (zinc finger MYND-type containing 19)protein interactions11622511721945450 SPON1,CTNND2
3.646e-02-3.31skin-scalp-malignant_melanomaCOSMIC cancer mutationsskin-scalp-malignant_melanoma63451682849 PREX2,SORBS1,PTPRZ1,NTM,NFIA
3.647e-02-3.31HYOU1 (hypoxia up-regulated 1)protein interactions1052528431945450 FGFR3,CPE,CLU
3.652e-02-3.31microtubule minus-end bindingmolecular functionGO:00510111411809448 MACF1
3.657e-02-3.31regulation of gliogenesisbiological processGO:001401311221820449 QKI,PTPRZ1
3.661e-02-3.31SNX27 (sorting nexin 27)protein interactions8160948941945450 CLU,ABLIM1,COL5A3,SLC1A3
3.680e-02-3.30P4HA1 (prolyl 4-hydroxylase subunit alpha 1)protein interactions503328531945450 APOE,PON2,DTNA
3.704e-02-3.30cell surface receptor signaling pathwaybiological processGO:00071661992101820449 CPE,GLI3,MACF1,SORBS1,CTNND2,NFIA,FGFR3,NDRG2,MAML2,BMPR1B
3.704e-02-3.30negative regulation of long-term synaptic potentiationbiological processGO:19002721411820449 APOE
3.704e-02-3.30cerebrospinal fluid circulationbiological processGO:00906601411820449 AQP4
3.704e-02-3.30sodium ion export across plasma membranebiological processGO:00363761411820449 SLC4A4
3.704e-02-3.30positive regulation of phospholipid transportbiological processGO:20011401411820449 APOE
3.704e-02-3.30radial glial cell differentiationbiological processGO:00600191411820449 GLI3
3.704e-02-3.30cellular response to purine-containing compoundbiological processGO:00714151411820449 RYR3
3.704e-02-3.30layer formation in cerebral cortexbiological processGO:00218191411820449 GLI3
3.704e-02-3.30acetyl-CoA biosynthetic processbiological processGO:00060851411820449 ACSS1
3.704e-02-3.30mechanosensory behaviorbiological processGO:00076381411820449 SLC1A3
3.704e-02-3.30positive regulation of myoblast proliferationbiological processGO:20002881411820449 MEIS2
3.704e-02-3.30glutathione biosynthetic processbiological processGO:00067501411820449 SLC1A2
3.715e-02-3.29Aquaporin-likeinterpro domainsIPR0232711411852150 AQP4
3.715e-02-3.29MIPinterpro domainsIPR0004251411852150 AQP4
3.721e-02-3.29Brenner_tumourCOSMIC cancer mutationsBrenner_tumour1311682849 FGFR3
3.721e-02-3.29skin-scalp-malignant_melanoma-nodularCOSMIC cancer mutationsskin-scalp-malignant_melanoma-nodular1311682849 PREX2
3.721e-02-3.29central_nervous_system-hypothalamus-glioma-astrocytoma_Grade_ICOSMIC cancer mutationscentral_nervous_system-hypothalamus-glioma-astrocytoma_Grade_I1311682849 QKI
3.721e-02-3.29skin-shoulder-malignant_melanoma-nodularCOSMIC cancer mutationsskin-shoulder-malignant_melanoma-nodular1311682849 PREX2
3.721e-02-3.29skin-back-carcinoma-basal_cell_carcinomaCOSMIC cancer mutationsskin-back-carcinoma-basal_cell_carcinoma1311682849 FGFR3
3.721e-02-3.29endometrium-ovary-endometriosisCOSMIC cancer mutationsendometrium-ovary-endometriosis1311682849 FGFR3
3.721e-02-3.29cervix-carcinoma-adenocarcinomaCOSMIC cancer mutationscervix-carcinoma-adenocarcinoma1311682849 FGFR3
3.728e-02-3.29GATA_ZN_FINGER_2prosite domainsPS501141111218642 TRPS1
3.728e-02-3.29LIPOCALINprosite domainsPS002131111218642 PTGDS
3.728e-02-3.29NC1_FIBprosite domainsPS514611111218642 COL5A3
3.728e-02-3.29FGFR3 ligand binding and activationREACTOME pathwaysR-HSA-1902391311028530 FGFR3
3.728e-02-3.29Passive transport by AquaporinsREACTOME pathwaysR-HSA-4320471311028530 AQP4
3.728e-02-3.29NOTCH2 intracellular domain regulates transcriptionREACTOME pathwaysR-HSA-21975631311028530 MAML2
3.728e-02-3.29Phospholipase C-mediated cascade; FGFR3REACTOME pathwaysR-HSA-56542271311028530 FGFR3
3.728e-02-3.29Notch-HLH transcription pathwayREACTOME pathwaysR-HSA-3500541311028530 MAML2
3.728e-02-3.29FGFR3c ligand binding and activationREACTOME pathwaysR-HSA-1903721311028530 FGFR3
3.745e-02-3.28HSPA1B (heat shock protein family A (Hsp70) member 1B)protein interactions330428731945450 NDRG2,ARHGAP24,FGFR3
3.745e-02-3.28PARD3 (par-3 family cell polarity regulator)protein interactions5628828731945450 PARD3B,SORBS1,DTNA
3.750e-02-3.28central_nervous_system-cerebellum-glioma-astrocytoma_Grade_ICOSMIC cancer mutationscentral_nervous_system-cerebellum-glioma-astrocytoma_Grade_I10521682849 QKI,GPC5
3.754e-02-3.28basal plasma membranecellular componentGO:000992528831910849 SLC4A4,SLC1A3,AQP4
3.757e-02-3.28EF_HAND_2prosite domainsPS5022221531218642 MACF1,SPARCL1,RYR3
3.759e-02-3.28human chr8p21.1chromosome locationhuman chr8p21.12012613450 CLU
3.764e-02-3.28HCO3TRNSPORTprints domainsPR01231101522720 SLC4A4
3.777e-02-3.28DDX27 (DEAD-box helicase 27)protein interactions5566128831945450 NTM,FGFR3,ARHGAP24
3.780e-02-3.28axolemmacellular componentGO:00306731511910849 SLC1A2
3.780e-02-3.28low-density lipoprotein particlecellular componentGO:00343621511910849 APOE
3.788e-02-3.27ZNF714 (zinc finger protein 714)protein interactions1482061511945450 ARHGAP24
3.788e-02-3.27ZNF813 (zinc finger protein 813)protein interactions1260171511945450 ARHGAP24
3.788e-02-3.27ZNF616 (zinc finger protein 616)protein interactions903171511945450 ARHGAP24
3.788e-02-3.27TMEM255B (transmembrane protein 255B)protein interactions3480131511945450 AMZ2
3.788e-02-3.27FGF9 (fibroblast growth factor 9)protein interactions22541511945450 FGFR3
3.788e-02-3.27IGSF1 (immunoglobulin superfamily member 1)protein interactions35471511945450 BMPR1B
3.798e-02-3.27Cadherin-like_dominterpro domainsIPR00212611421852150 CDH20,PCDH9
3.808e-02-3.27learning or memorybiological processGO:000761127631820449 PTPRZ1,MEIS2,APOE
3.809e-02-3.27thyroid-carcinomaCOSMIC cancer mutationsthyroid-carcinoma4126181682849 ATP13A4,AQP4,CPE,SPARCL1,TRPS1,GPC5,NFIA,LSAMP,CTNND2,RYR3,MACF1,DTNA,PTPRZ1,FGFR3,PCDH9,ACSS1,GLIS3,COL5A3
3.855e-02-3.26calcium channel activitymolecular functionGO:000526211721809448 RYR3,GPM6A
3.864e-02-3.25MIPpfam domainsPF002301411779550 AQP4
3.864e-02-3.25GATApfam domainsPF003201411779550 TRPS1
3.872e-02-3.25MED15 (mediator complex subunit 15)protein interactions5158612121945450 QKI,NFIA
3.880e-02-3.25skin-scalp-carcinoma-squamous_cell_carcinomaCOSMIC cancer mutationsskin-scalp-carcinoma-squamous_cell_carcinoma159691682849 SLC4A4,ATP13A4,MACF1,TRPS1,GPC5,PTPRZ1,FGFR3,LSAMP,COL5A3
3.886e-02-3.25positive regulation of macromolecule biosynthetic processbiological processGO:00105572592121820449 APOE,CLU,GLI3,SPON1,SORBS1,MEIS2,NPAS3,GLIS3,QKI,NFIA,BMPR1B,MAML2
3.888e-02-3.25Composition of Lipid ParticlesWikiPathwaysWP3601101531021 APOE
3.894e-02-3.25COLFIsmart domainsSM00038111971735 COL5A3
3.896e-02-3.25Propanoate MetabolismSMPDB pathwaysSMP000001618113693 ACSS1
3.896e-02-3.25Methylmalonic Aciduria Due to Cobalamin-Related DisordersSMPDB pathwaysSMP000020118113693 ACSS1
3.896e-02-3.25Malonic AciduriaSMPDB pathwaysSMP000019818113693 ACSS1
3.896e-02-3.25Malonyl-CoA Decarboxylase DeficiencySMPDB pathwaysSMP000050218113693 ACSS1
3.908e-02-3.24AMP bindingmolecular functionGO:00162081511809448 ACSS1
3.908e-02-3.24neurexin family protein bindingmolecular functionGO:00420431511809448 CPE
3.908e-02-3.24phosphatidylglycerol bindingmolecular functionGO:19016111511809448 PITPNC1
3.914e-02-3.24skin-leg-malignant_melanoma-nodularCOSMIC cancer mutationsskin-leg-malignant_melanoma-nodular25831682849 ATP13A4,SLC4A4,PTPRZ1
3.920e-02-3.24Cadherin-like_sfinterpro domainsIPR01591911621852150 CDH20,PCDH9
3.930e-02-3.24BRK1 (BRICK1 subunit of SCAR/WAVE actin nucleating complex)protein interactions5584512221945450 DTNA,NHSL1
3.930e-02-3.24MED31 (mediator complex subunit 31)protein interactions5100312221945450 QKI,CPE
3.935e-02-3.24perinuclear region of cytoplasmcellular componentGO:004847173551910849 MEIS2,PTGDS,NDRG2,SLC1A3,CLU
3.943e-02-3.23human chr13q31.3chromosome locationhuman chr13q31.32112613450 GPC5
3.943e-02-3.23human chr4q32.3chromosome locationhuman chr4q32.32112613450 CPE
3.954e-02-3.23Cadherinpfam domainsPF0002811221779550 CDH20,PCDH9
3.963e-02-3.23lung-carcinoma-squamous_cell_carcinomaCOSMIC cancer mutationslung-carcinoma-squamous_cell_carcinoma14664471682849 PON2,DTNA,APOE,GLI3,FGFR3,PCDH9,AMZ2,NKAIN3,ARHGAP24,CDH20,PREX2,PARD3B,MACF1,PITPNC1,GLIS3,PTPRZ1,SPON1,SLC1A3,NPAS3,MEIS2,ATP13A4,QKI,SLC4A4,NTM,CTNND2,GPC5,MAML2,ABLIM1,CLU,COL5A3,FBXL7,ACSS1,PTGDS,NHSL1,MSI2,PAMR1,GPM6A,SORBS1,NFIA,TRPS1,BMPR1B,CPE,AQP4,LSAMP,RYR3,SLC1A2,SPARCL1
3.964e-02-3.23exit from mitosisbiological processGO:00104581511820449 NFIA
3.964e-02-3.23regulation of phospholipid transportbiological processGO:20011381511820449 APOE
3.964e-02-3.23regulation of neuron projection arborizationbiological processGO:01500111511820449 MACF1
3.964e-02-3.23positive regulation of cholesterol metabolic processbiological processGO:00902051511820449 APOE
3.964e-02-3.23positive regulation of glycogen biosynthetic processbiological processGO:00457251511820449 SORBS1
3.964e-02-3.23chondrocyte proliferationbiological processGO:00359881511820449 FGFR3
3.964e-02-3.23protein homotrimerizationbiological processGO:00702071511820449 SLC1A2
3.964e-02-3.23lipoprotein catabolic processbiological processGO:00421591511820449 APOE
3.964e-02-3.23dorsal/ventral neural tube patterningbiological processGO:00219041511820449 GLI3
3.964e-02-3.23sarcoplasmic reticulum calcium ion transportbiological processGO:00702961511820449 RYR3
3.964e-02-3.23regulation of circadian sleep/wake cycle, sleepbiological processGO:00451871511820449 PTGDS
3.964e-02-3.23synapse maturationbiological processGO:00600741511820449 NFIA
3.964e-02-3.23response to caffeinebiological processGO:00310001511820449 RYR3
3.975e-02-3.23Znf_GATAinterpro domainsIPR0006791511852150 TRPS1
3.988e-02-3.22PAX7 (paired box 7)protein interactions508112321945450 TRPS1,NFIA
4.002e-02-3.22soft_tissue-small_round_cell_tumourCOSMIC cancer mutationssoft_tissue-small_round_cell_tumour1411682849 FGFR3
4.002e-02-3.22endometriosisCOSMIC cancer mutationsendometriosis1411682849 FGFR3
4.002e-02-3.22in_situ_neoplasmCOSMIC cancer mutationsin_situ_neoplasm1411682849 FGFR3
4.002e-02-3.22small_round_cell_tumourCOSMIC cancer mutationssmall_round_cell_tumour1411682849 FGFR3
4.002e-02-3.22urinary_tract-renal_pelvis-carcinoma-transitional_cell_carcinomaCOSMIC cancer mutationsurinary_tract-renal_pelvis-carcinoma-transitional_cell_carcinoma1411682849 FGFR3
4.010e-02-3.22DCC mediated attractive signalingREACTOME pathwaysR-HSA-4188851411028530 ABLIM1
4.035e-02-3.21CDH12 (cadherin 12)protein interactions10101611945450 CTNNA2
4.035e-02-3.21CTSK (cathepsin K)protein interactions15131611945450 FGFR3
4.035e-02-3.21FNDC8 (fibronectin type III domain containing 8)protein interactions547521611945450 SPARCL1
4.035e-02-3.21HLA-H (major histocompatibility complex, class I, H (pseudogene))protein interactions31361611945450 FGFR3
4.035e-02-3.21SAPCD1 (suppressor APC domain containing 1)protein interactions4012511611945450 CTNNA2
4.035e-02-3.21VGLL1 (vestigial like family member 1)protein interactions514421611945450 MEIS2
4.035e-02-3.21AMMECR1L (AMMECR1 like)protein interactions836071611945450 MACF1
4.035e-02-3.21CYP2C8 (cytochrome P450 family 2 subfamily C member 8)protein interactions15581611945450 APOE
4.035e-02-3.21GMPR2 (guanosine monophosphate reductase 2)protein interactions512921611945450 ARHGAP24
4.060e-02-3.20protein maturationbiological processGO:005160448341820449 GLI3,CPE,CLU,SPON1
4.065e-02-3.20membrane protein complexcellular componentGO:0098796126171910849 SORBS1,BMPR1B,SLC1A3,CDH20,RYR3,CTNNA2,SLC1A2
4.079e-02-3.20SP7 (Sp7 transcription factor)protein interactions12134029731945450 NFIA,TRPS1,QKI
4.079e-02-3.20urinary_tract-bladder-carcinoma-transitional_cell_carcinomaCOSMIC cancer mutationsurinary_tract-bladder-carcinoma-transitional_cell_carcinoma6040241682849 GPC5,SPARCL1,ATP13A4,SLC4A4,GLIS3,SLC1A3,PTPRZ1,MACF1,GPM6A,SORBS1,PREX2,NFIA,TRPS1,PARD3B,CDH20,COL5A3,ACSS1,PCDH9,FGFR3,GLI3,ABLIM1,CLU,DTNA,PON2
4.095e-02-3.20transitional_cell_carcinomaCOSMIC cancer mutationstransitional_cell_carcinoma6042241682849 DTNA,ABLIM1,CLU,PON2,ACSS1,COL5A3,PCDH9,GLI3,FGFR3,CDH20,SORBS1,GPM6A,PREX2,TRPS1,NFIA,PARD3B,MACF1,GLIS3,SLC1A3,PTPRZ1,SLC4A4,ATP13A4,SPARCL1,GPC5
4.115e-02-3.19negative regulation of cellular component organizationbiological processGO:005112970951820449 CLU,ARHGAP24,CTNNA2,APOE,CST3
4.117e-02-3.19secondary active transmembrane transporter activitymolecular functionGO:001529128931809448 SLC1A2,SLC1A3,SLC4A4
4.118e-02-3.19skin-extremity-malignant_melanomaCOSMIC cancer mutationsskin-extremity-malignant_melanoma1875101682849 ACSS1,FBXL7,COL5A3,PREX2,RYR3,PTPRZ1,PCDH9,ATP13A4,CDH20,PITPNC1
4.121e-02-3.19basal_(triple-negative)_carcinomaCOSMIC cancer mutationsbasal_(triple-negative)_carcinoma2981141682849 PON2,MAML2,MACF1,NDRG2,GLI3,FGFR3,BMPR1B,MSI2,NTM,ARHGAP24,SLC4A4,NPAS3,MEIS2,SPARCL1
4.121e-02-3.19breast-carcinoma-basal_(triple-negative)_carcinomaCOSMIC cancer mutationsbreast-carcinoma-basal_(triple-negative)_carcinoma2981141682849 MACF1,MAML2,PON2,BMPR1B,GLI3,FGFR3,NDRG2,SLC4A4,MEIS2,NPAS3,MSI2,ARHGAP24,NTM,SPARCL1
4.126e-02-3.19cell junction assemblybiological processGO:003432928531820449 CDH20,GPM6A,SORBS1
4.127e-02-3.19human chr3q13.31chromosome locationhuman chr3q13.312212613450 LSAMP
4.144e-02-3.18striated muscle contractionbiological processGO:000694112021820449 DTNA,RYR3
4.156e-02-3.18cellular component organization or biogenesisbiological processGO:00718405850221820449 GLI3,ABLIM1,CTNNA2,SPARCL1,RYR3,SORBS1,GPM6A,PARD3B,NFIA,PREX2,AQP4,SLC1A2,BMPR1B,PTPRZ1,CDH20,MACF1,CTNND2,APOE,PITPNC1,CST3,CLU,COL5A3
4.163e-02-3.18water channel activitymolecular functionGO:00152501611809448 AQP4
4.163e-02-3.18misfolded protein bindingmolecular functionGO:00517871611809448 CLU
4.166e-02-3.18SYP (synaptophysin)protein interactions685512621945450 GPM6A,PITPNC1
4.166e-02-3.18RNF115 (ring finger protein 115)protein interactions2724612621945450 NDRG2,CST3
4.176e-02-3.18Glycerol uptake facilitator proteingene3d domains1.20.1080.101411447044 AQP4
4.198e-02-3.17ossificationbiological processGO:000150328731820449 BMPR1B,GLI3,FGFR3
4.223e-02-3.16insulin metabolic processbiological processGO:19011421611820449 CPE
4.223e-02-3.16locomotory exploration behaviorbiological processGO:00356411611820449 APOE
4.223e-02-3.16nonribosomal peptide biosynthetic processbiological processGO:00191841611820449 SLC1A2
4.223e-02-3.16nose developmentbiological processGO:00435841611820449 GLI3
4.223e-02-3.16positive regulation of membrane protein ectodomain proteolysisbiological processGO:00510441611820449 APOE
4.223e-02-3.16low-density lipoprotein particle remodelingbiological processGO:00343741611820449 APOE
4.223e-02-3.16non-proteinogenic amino acid biosynthetic processbiological processGO:01700431611820449 SLC1A3
4.223e-02-3.16spinal cord dorsal/ventral patterningbiological processGO:00215131611820449 GLI3
4.223e-02-3.16cardiac left ventricle morphogenesisbiological processGO:00032141611820449 CPE
4.223e-02-3.16wound healing, spreading of epidermal cellsbiological processGO:00353131611820449 ARHGAP24
4.223e-02-3.16short-chain fatty acid metabolic processbiological processGO:00464591611820449 ACSS1
4.235e-02-3.16CarboxyPept-like_regulatoryinterpro domainsIPR0089691611852150 CPE
4.240e-02-3.16DWAsmart domainsSM00523121971735 NFIA
4.240e-02-3.16ZnF_GATAsmart domainsSM00401121971735 TRPS1
4.273e-02-3.15apical dendritecellular componentGO:00974401711910849 CLU
4.282e-02-3.15ureterCOSMIC cancer mutationsureter1511682849 FGFR3
4.282e-02-3.15hypothalamusCOSMIC cancer mutationshypothalamus1511682849 QKI
4.282e-02-3.15Pef1 (penta-EF hand domain containing 1)protein interactions678981711945450 QKI
4.282e-02-3.15RASL12 (RAS like family 12)protein interactions512851711945450 BMPR1B
4.282e-02-3.15TAGAP (T cell activation RhoGTPase activating protein)protein interactions1172891711945450 DTNA
4.282e-02-3.15Shcbp1 (Shc SH2-domain binding protein 1)protein interactions204191711945450 GPC5
4.282e-02-3.15DPP6 (dipeptidyl peptidase like 6)protein interactions18041711945450 GPM6A
4.282e-02-3.15SEPSECS (Sep (O-phosphoserine) tRNA:Sec (selenocysteine) tRNA synthase)protein interactions510911711945450 ABLIM1
4.282e-02-3.15ZNF557 (zinc finger protein 557)protein interactions792301711945450 ARHGAP24
4.282e-02-3.15Sqstm1 (sequestosome 1)protein interactions184121711945450 BMPR1B
4.282e-02-3.15C16orf92 (chromosome 16 open reading frame 92)protein interactions1463781711945450 APOE
4.282e-02-3.15NOTCH4 (notch receptor 4)protein interactions48551711945450 MAML2
4.282e-02-3.15PAX4 (paired box 4)protein interactions50781711945450 NTM
4.286e-02-3.15MYB (MYB proto-oncogene, transcription factor)protein interactions460212821945450 NFIA,TRPS1
4.290e-02-3.15Synthesis of Prostaglandins (PG) and Thromboxanes (TX)REACTOME pathwaysR-HSA-21621231511028530 PTGDS
4.346e-02-3.14POLA2 (DNA polymerase alpha 2, accessory subunit)protein interactions2364912921945450 FGFR3,CPE
4.362e-02-3.13bone-extraskeletal-Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumourCOSMIC cancer mutationsbone-extraskeletal-Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour89161682849 FGFR3,PTPRZ1,SPARCL1,NPAS3,ABLIM1,PTGDS
4.367e-02-3.13monoatomic ion transportbiological processGO:000681196461820449 SLC4A4,SLC1A2,ATP13A4,RYR3,GPM6A,SLC1A3
4.389e-02-3.13actin cytoskeletoncellular componentGO:001562952041910849 CTNNA2,MACF1,SORBS1,ABLIM1
4.391e-02-3.13CARBOXYPEPT_ZN_2prosite domainsPS001331311218642 CPE
4.391e-02-3.13CARBOXYPEPT_ZN_1prosite domainsPS001321311218642 CPE
4.397e-02-3.12positive regulation of lipid metabolic processbiological processGO:004583412421820449 SORBS1,APOE
4.400e-02-3.12basal part of cellcellular componentGO:004517830731910849 SLC4A4,SLC1A3,AQP4
4.415e-02-3.12establishment of localizationbiological processGO:00512343887161820449 GLI3,PARD3B,GPM6A,RYR3,AQP4,SLC4A4,QKI,SLC1A2,CPE,ATP13A4,PITPNC1,APOE,MACF1,SLC1A3,PTGDS,CLU
4.417e-02-3.12transmembrane receptor protein tyrosine phosphatase activitymolecular functionGO:00050011711809448 PTPRZ1
4.417e-02-3.12transmembrane receptor protein phosphatase activitymolecular functionGO:00191981711809448 PTPRZ1
4.472e-02-3.11middle_lobeCOSMIC cancer mutationsmiddle_lobe138281682849 MACF1,ATP13A4,CPE,CTNND2,RYR3,FGFR3,PARD3B,PCDH9
4.481e-02-3.11cell population proliferationbiological processGO:000828372651820449 GLI3,NDRG2,NFIA,FGFR3,CLU
4.481e-02-3.11embryonic digestive tract morphogenesisbiological processGO:00485571711820449 GLI3
4.481e-02-3.11specification of animal organ identitybiological processGO:00100921711820449 GLI3
4.481e-02-3.11high-density lipoprotein particle remodelingbiological processGO:00343751711820449 APOE
4.481e-02-3.11positive regulation of vascular permeabilitybiological processGO:00431171711820449 APOE
4.481e-02-3.11negative regulation of triglyceride metabolic processbiological processGO:00902091711820449 APOE
4.481e-02-3.11positive regulation of glycogen metabolic processbiological processGO:00708751711820449 SORBS1
4.481e-02-3.11viral genome replicationbiological processGO:00190791711820449 NFIA
4.481e-02-3.11cell migration in hindbrainbiological processGO:00215351711820449 CTNNA2
4.481e-02-3.11fatty acid homeostasisbiological processGO:00550891711820449 APOE
4.481e-02-3.11protein trimerizationbiological processGO:00702061711820449 SLC1A2
4.481e-02-3.11regulation of inclusion body assemblybiological processGO:00900831711820449 CLU
4.481e-02-3.11ureter developmentbiological processGO:00721891711820449 NFIA
4.481e-02-3.11cellular response to ATPbiological processGO:00713181711820449 RYR3
4.493e-02-3.10regulation of ERK1 and ERK2 cascadebiological processGO:007037229531820449 APOE,NDRG2,FGFR3
4.493e-02-3.10AMP-bd_Cinterpro domainsIPR0251101711852150 ACSS1
4.493e-02-3.10CA_dom_sfinterpro domainsIPR0363981711852150 PTPRZ1
4.493e-02-3.10CA_dominterpro domainsIPR0011481711852150 PTPRZ1
4.493e-02-3.10Cystatin_dominterpro domainsIPR0000101711852150 CST3
4.499e-02-3.10AFDN (afadin, adherens junction formation factor)protein interactions430130931945450 SORBS1,DTNA,MACF1
4.525e-02-3.10positive regulation of cellular biosynthetic processbiological processGO:00313282652121820449 APOE,CLU,NPAS3,MEIS2,SORBS1,SPON1,GLI3,MAML2,BMPR1B,NFIA,QKI,GLIS3
4.529e-02-3.09Tgfbr1 (transforming growth factor, beta receptor I)protein interactions218121811945450 BMPR1B
4.529e-02-3.09OPCML (opioid binding protein/cell adhesion molecule like)protein interactions49781811945450 NTM
4.529e-02-3.09ZNF100 (zinc finger protein 100)protein interactions1632271811945450 ARHGAP24
4.529e-02-3.09NKIRAS1 (NFKB inhibitor interacting Ras like 1)protein interactions285121811945450 BMPR1B
4.529e-02-3.09NECTIN1 (nectin cell adhesion molecule 1)protein interactions58181811945450 FGFR3
4.529e-02-3.09TTC29 (tetratricopeptide repeat domain 29)protein interactions838941811945450 MACF1
4.529e-02-3.09KLHL1 (kelch like family member 1)protein interactions576261811945450 BMPR1B
4.529e-02-3.09Lck (lymphocyte protein tyrosine kinase)protein interactions168181811945450 APOE
4.529e-02-3.09AK9 (adenylate kinase 9)protein interactions2212641811945450 ARHGAP24
4.529e-02-3.09Cnot2 (CCR4-NOT transcription complex, subunit 2)protein interactions720681811945450 MACF1
4.529e-02-3.09PTGFR (prostaglandin F receptor)protein interactions57371811945450 PTGDS
4.529e-02-3.09CYP2E1 (cytochrome P450 family 2 subfamily E member 1)protein interactions15711811945450 CLU
4.530e-02-3.09GPIHBP1 (glycosylphosphatidylinositol anchored high density lipoprotein binding protein 1)protein interactions33832813221945450 CPE,FGFR3
4.535e-02-3.09C11orf52 (chromosome 11 open reading frame 52)protein interactions9189431031945450 DTNA,ABLIM1,MACF1
4.557e-02-3.09cytoskeletal protein bindingmolecular functionGO:000809298961809448 CLU,APOE,CTNNA2,ABLIM1,SORBS1,MACF1
4.561e-02-3.09normalCOSMIC cancer mutationsnormal1611682849 FGFR3
4.561e-02-3.09urinary_tract-carcinomaCOSMIC cancer mutationsurinary_tract-carcinoma1611682849 FGFR3
4.561e-02-3.09flankCOSMIC cancer mutationsflank1611682849 FGFR3
4.561e-02-3.09renal_pelvisCOSMIC cancer mutationsrenal_pelvis1611682849 FGFR3
4.569e-02-3.09carboxylic acid transportbiological processGO:004694229731820449 SLC1A3,APOE,SLC1A2
4.606e-02-3.08extraskeletalCOSMIC cancer mutationsextraskeletal90361682849 ABLIM1,PTGDS,NPAS3,SPARCL1,FGFR3,PTPRZ1
4.607e-02-3.08organic acid transportbiological processGO:001584929831820449 APOE,SLC1A2,SLC1A3
4.613e-02-3.08PDZpfam domainsPF0059512221779550 PARD3B,PREX2
4.649e-02-3.07MFAP5-mediated ovarian cancer cell motility and invasivenessWikiPathwaysWP3301121531021 RYR3
4.649e-02-3.07Bone Morphogenic Protein (BMP) Signalling and RegulationWikiPathwaysWP1425121531021 BMPR1B
4.652e-02-3.07cellular response to organonitrogen compoundbiological processGO:007141750541820449 RYR3,SORBS1,SLC1A2,SLC1A3
4.655e-02-3.07myelinationbiological processGO:004255212821820449 QKI,CLU
4.671e-02-3.06intracellularly gated calcium channel activitymolecular functionGO:00152781811809448 RYR3
4.671e-02-3.06phosphatidylcholine transporter activitymolecular functionGO:00085251811809448 PITPNC1
4.671e-02-3.06heparan sulfate proteoglycan bindingmolecular functionGO:00433951811809448 APOE
4.673e-02-3.06ZZpfam domainsPF005691711779550 DTNA
4.673e-02-3.06AMP-binding_Cpfam domainsPF131931711779550 ACSS1
4.673e-02-3.06Carb_anhydrasepfam domainsPF001941711779550 PTPRZ1
4.673e-02-3.06Cystatinpfam domainsPF000311711779550 CST3
4.674e-02-3.06GRB2 (growth factor receptor bound protein 2)protein interactions288576951945450 SLC1A2,MSI2,CLU,PON2,FGFR3
4.696e-02-3.06Cadherinsgene3d domains2.60.40.6011421447044 PCDH9,CDH20
4.716e-02-3.05NTRK2 (neurotrophic receptor tyrosine kinase 2)protein interactions491513521945450 ABLIM1,DTNA
4.716e-02-3.05BMP4 (bone morphogenetic protein 4)protein interactions65213521945450 CLU,BMPR1B
4.716e-02-3.05SOX15 (SRY-box transcription factor 15)protein interactions666513521945450 TRPS1,NFIA
4.716e-02-3.05Myo1c (myosin IC)protein interactions1791313521945450 TRPS1,ABLIM1
4.718e-02-3.05Glutamatergic synapseKEGG pathwayshsa047241142716122 SLC1A2,SLC1A3
4.718e-02-3.05Glutamatergic synapseKEGG pathwaysko047241142716122 SLC1A3,SLC1A2
4.721e-02-3.05regulation of cell population proliferationbiological processGO:0042127179091820449 CLU,FGFR3,NDRG2,BMPR1B,PTPRZ1,GLI3,PTGDS,APOE,MEIS2
4.722e-02-3.05central_nervous_system-brain-glioma-astrocytoma_Grade_IVCOSMIC cancer mutationscentral_nervous_system-brain-glioma-astrocytoma_Grade_IV15813491682849 PREX2,PARD3B,CDH20,ARHGAP24,AMZ2,NKAIN3,PCDH9,GLI3,FGFR3,DTNA,PON2,APOE,CTNND2,GPC5,SLC4A4,ATP13A4,QKI,NPAS3,MEIS2,NTM,GLIS3,SLC1A3,SPON1,NDRG2,PTPRZ1,MACF1,PITPNC1,SORBS1,GPM6A,TRPS1,NFIA,PTGDS,PAMR1,MSI2,NHSL1,ACSS1,FBXL7,COL5A3,CST3,CLU,ABLIM1,MAML2,SLC1A2,RYR3,LSAMP,SPARCL1,AQP4,CPE,BMPR1B
4.737e-02-3.05circulatory system processbiological processGO:000301350841820449 SLC4A4,SLC1A3,APOE,SLC1A2
4.738e-02-3.05myelin maintenancebiological processGO:00432171811820449 CLU
4.738e-02-3.05dendritic spine morphogenesisbiological processGO:00609971811820449 CTNND2
4.738e-02-3.05negative regulation of platelet activationbiological processGO:00105441811820449 APOE
4.738e-02-3.05spinal cord patterningbiological processGO:00215111811820449 GLI3
4.738e-02-3.05response to misfolded proteinbiological processGO:00517881811820449 CLU
4.738e-02-3.05regulation of extracellular matrix disassemblybiological processGO:00107151811820449 CST3
4.752e-02-3.05ATPase_P-typ_cation-transptr_Ninterpro domainsIPR0040141811852150 ATP13A4
4.752e-02-3.05Leu-rich_rpt_Cys-con_subtypinterpro domainsIPR0065531811852150 FBXL7
4.754e-02-3.05ZYX (zyxin)protein interactions779131631945450 MACF1,ABLIM1,SORBS1
4.764e-02-3.04parallel fiber to Purkinje cell synapsecellular componentGO:00986881911910849 GPM6A
4.774e-02-3.04CCL14 (C-C motif chemokine ligand 14)protein interactions63581911945450 AMZ2
4.774e-02-3.04SPZ1 (spermatogenic leucine zipper 1)protein interactions846541911945450 DTNA
4.774e-02-3.04FBXO27 (F-box protein 27)protein interactions1264331911945450 CLU
4.774e-02-3.04CNTNAP4 (contactin associated protein family member 4)protein interactions854451911945450 MACF1
4.774e-02-3.04TNR (tenascin R)protein interactions71431911945450 PTPRZ1
4.774e-02-3.04PHYHIPL (phytanoyl-CoA 2-hydroxylase interacting protein like)protein interactions844571911945450 GPM6A
4.774e-02-3.04ZNF138 (zinc finger protein 138)protein interactions76971911945450 ARHGAP24
4.786e-02-3.04ensheathment of neuronsbiological processGO:000727213021820449 CLU,QKI
4.786e-02-3.04axon ensheathmentbiological processGO:000836613021820449 CLU,QKI
4.804e-02-3.04acute_lymphoblastic_leukaemiaCOSMIC cancer mutationsacute_lymphoblastic_leukaemia2197111682849 ARHGAP24,DTNA,SLC4A4,PTPRZ1,PARD3B,GLI3,FGFR3,TRPS1,NFIA,PREX2,BMPR1B
4.839e-02-3.03skin-other-verrucal_keratosis_BRAF_inhibitor_relatedCOSMIC cancer mutationsskin-other-verrucal_keratosis_BRAF_inhibitor_related1711682849 FGFR3
4.839e-02-3.03central_nervous_system-optic_nerve-glioma-astrocytoma_Grade_ICOSMIC cancer mutationscentral_nervous_system-optic_nerve-glioma-astrocytoma_Grade_I1711682849 QKI
4.839e-02-3.03optic_nerveCOSMIC cancer mutationsoptic_nerve1711682849 QKI
4.839e-02-3.03breast-carcinoma-neuroendocrine_carcinomaCOSMIC cancer mutationsbreast-carcinoma-neuroendocrine_carcinoma1711682849 FGFR3
4.839e-02-3.03non_chronically_sun_exposed_siteCOSMIC cancer mutationsnon_chronically_sun_exposed_site1711682849 FGFR3
4.839e-02-3.03skin-carcinoma-squamous_cell_carcinoma_BRAF_inhibitor_relatedCOSMIC cancer mutationsskin-carcinoma-squamous_cell_carcinoma_BRAF_inhibitor_related1711682849 FGFR3
4.839e-02-3.03squamous_cell_carcinoma_BRAF_inhibitor_relatedCOSMIC cancer mutationssquamous_cell_carcinoma_BRAF_inhibitor_related1711682849 FGFR3
4.839e-02-3.03skin-non_chronically_sun_exposed_site-malignant_melanomaCOSMIC cancer mutationsskin-non_chronically_sun_exposed_site-malignant_melanoma1711682849 FGFR3
4.839e-02-3.03verrucal_keratosis_BRAF_inhibitor_relatedCOSMIC cancer mutationsverrucal_keratosis_BRAF_inhibitor_related1711682849 FGFR3
4.852e-02-3.03carboxylic acid transmembrane transportbiological processGO:190503913121820449 SLC1A3,SLC1A2
4.859e-02-3.02human chr18q12.1chromosome locationhuman chr18q12.12612613450 DTNA
4.879e-02-3.02transportbiological processGO:00068103615151820449 CLU,MACF1,PITPNC1,APOE,PTGDS,SLC1A3,ATP13A4,CPE,SLC1A2,QKI,SLC4A4,AQP4,RYR3,GPM6A,GLI3
4.893e-02-3.02kidney-other-neoplasmCOSMIC cancer mutationskidney-other-neoplasm10653371682849 MACF1,SPON1,SLC1A3,PTPRZ1,QKI,ATP13A4,AQP4,CPE,MEIS2,NPAS3,RYR3,CTNND2,SLC1A2,LSAMP,GPC5,SPARCL1,ABLIM1,CLU,DTNA,MAML2,PON2,COL5A3,ACSS1,FBXL7,PCDH9,NKAIN3,AMZ2,FGFR3,GLI3,NHSL1,PAMR1,CDH20,ARHGAP24,GPM6A,SORBS1,PREX2,TRPS1
4.905e-02-3.01NFIB (nuclear factor I B)protein interactions478113821945450 NFIA,TRPS1
4.916e-02-3.01regulation of small GTPase mediated signal transductionbiological processGO:005105630631820449 ARHGAP24,PREX2,APOE
4.918e-02-3.01amino acid transportbiological processGO:000686513221820449 SLC1A3,SLC1A2
4.924e-02-3.01transmembrane receptor protein serine/threonine kinase activitymolecular functionGO:00046751911809448 BMPR1B
4.924e-02-3.01water transmembrane transporter activitymolecular functionGO:00053721911809448 AQP4
4.931e-02-3.01TRIM67 (tripartite motif containing 67)protein interactions4407304804181945450 APOE,CTNNA2,SLC4A4,CLU,CST3,QKI,SLC1A3,MACF1,DTNA,CTNND2,GPM6A,MSI2,LSAMP,PON2,NTM,PTPRZ1,PITPNC1,ACSS1
4.940e-02-3.01ACTA1 (actin alpha 1, skeletal muscle)protein interactions5832131945450 DTNA,MACF1,SORBS1
4.941e-02-3.01Cation_ATPase_Npfam domainsPF006901811779550 ATP13A4
4.962e-02-3.00thalamusCOSMIC cancer mutationsthalamus28431682849 QKI,DTNA,FGFR3
4.968e-02-3.00DUSP22 (dual specificity phosphatase 22)protein interactions5694013921945450 QKI,CTNNA2
4.995e-02-3.00negative regulation of alcohol biosynthetic processbiological processGO:19029311911820449 APOE
4.995e-02-3.00craniofacial suture morphogenesisbiological processGO:00970941911820449 GLI3
4.995e-02-3.00regulation of circadian sleep/wake cyclebiological processGO:00427491911820449 PTGDS
4.995e-02-3.00vocalization behaviorbiological processGO:00716251911820449 GLI3
4.995e-02-3.00cartilage condensationbiological processGO:00015021911820449 BMPR1B
4.995e-02-3.00vascular associated smooth muscle cell differentiationbiological processGO:00358861911820449 QKI