Gene Ontology Enrichment Results

Homer de novo Motif Enrichment Results
Known Motif Enrichment Results

Text file version of complete results (i.e. open with Excel)

biological process: Functional groupings of proteins (Gene Ontology)

molecular function: Mechanistic actions of proteins (Gene Ontology)

cellular component: Protein localization (Gene Ontology)

chromosome location: Genes with similar chromosome localization (NCBI Gene)

KEGG pathways: Groups of proteins in the same pathways (KEGG)

protein interactions: "Proteins interacting with a common protein (BIND, EcoCyc, HPRD)" (NCBI Gene)

interpro domains: Proteins with similar domains and features (Interpro)

pfam domains: Proteins with similar domains and features (Pfam)

smart domains: Proteins with similar domains and features (SMART)

gene3d domains: Proteins with similar domains and features (Gene3D)

prosite domains: Proteins with similar domains and features (Prosite)

prints domains: Proteins with similar domains and features (PRINTS)

MSigDB lists: "Genes sets for pathways, factor/miRNA target predictions, expression patterns, etc." (MSigDB)

BIOCYC pathways: Groups of proteins in the same pathways (BIOCYC)

COSMIC cancer mutations: Genes mutated in similar cancers (COSMIC)

GWAS genes: Genes mutated in similar diseases (GWAS Catalog)

Lipid Maps pathways: Groups of proteins in the same lipid pathways (Lipid Maps/Biosystems)

Pathway Interaction DB: Groups of proteins in the same pathways (Pathway Interaction Database)

REACTOME pathways: Groups of proteins in the same pathways (REACTOME)

SMPDB pathways: Groups of proteins in the same pathways (SMPDB)

WikiPathways: Groups of proteins in the same pathways (Wikipathways)

Enriched Categories

P-value	ln(P)	Term	GO Tree	GO ID	# of Genes in Term	# of Target Genes in Term	# of Total Genes	# of Target Genes	Common Genes
1.275e-10	-22.78	PRNP (prion protein (Kanno blood group))	protein interactions	5621	1118	18	19454	50	LSAMP,SORBS1,PTPRZ1,MACF1,GPM6A,MSI2,CLU,SPARCL1,AQP4,TRPS1,NHSL1,SLC1A3,QKI,ABLIM1,APOE,CPE,MAML2,SLC4A4
7.292e-07	-14.13	soft_tissue	COSMIC cancer mutations	soft_tissue	5828	34	16828	49	CLU,MAML2,PON2,APOE,COL5A3,FBXL7,PCDH9,NKAIN3,FGFR3,GLI3,NHSL1,CDH20,PAMR1,ARHGAP24,GPM6A,SORBS1,PREX2,NFIA,TRPS1,PARD3B,MACF1,GLIS3,SPON1,SLC1A3,PTPRZ1,AQP4,MEIS2,NPAS3,RYR3,CTNND2,SLC1A2,LSAMP,GPC5,SPARCL1
1.343e-06	-13.52	blood_vessel	COSMIC cancer mutations	blood_vessel	2211	20	16828	49	MEIS2,ARHGAP24,CDH20,LSAMP,PREX2,GPM6A,RYR3,SLC1A2,CTNND2,GPC5,MAML2,COL5A3,FBXL7,FGFR3,GLI3,PTPRZ1,SPON1,PCDH9,SLC1A3,NKAIN3
1.475e-06	-13.43	cerebellum	COSMIC cancer mutations	cerebellum	769	12	16828	49	CPE,QKI,NPAS3,MEIS2,CTNND2,RYR3,GPC5,PARD3B,ABLIM1,MAML2,PCDH9,PTPRZ1
1.565e-06	-13.37	nervous system development	biological process	GO:0007399	2185	19	18204	49	PTPRZ1,SLC1A3,LSAMP,CTNND2,APOE,CLU,MSI2,PCDH9,GLI3,CTNNA2,MEIS2,GPM6A,NFIA,NDRG2,QKI,PREX2,NTM,SLC1A2,BMPR1B
1.606e-06	-13.34	cell morphogenesis	biological process	GO:0000902	687	11	18204	49	NFIA,PREX2,BMPR1B,GLI3,GPM6A,CTNNA2,CLU,CDH20,PTPRZ1,CTNND2,SLC1A3
1.845e-06	-13.20	prostate-carcinoma	COSMIC cancer mutations	prostate-carcinoma	9000	42	16828	49	SPARCL1,GPC5,LSAMP,CTNND2,SLC1A2,RYR3,NTM,NPAS3,MEIS2,SLC4A4,ATP13A4,QKI,CPE,PTPRZ1,SLC1A3,SPON1,GLIS3,BMPR1B,PITPNC1,MACF1,PARD3B,TRPS1,NFIA,PREX2,SORBS1,GPM6A,ARHGAP24,MSI2,CDH20,NHSL1,GLI3,FGFR3,NKAIN3,PCDH9,FBXL7,COL5A3,APOE,PON2,MAML2,DTNA,ABLIM1,CLU
3.226e-06	-12.64	Burkitt_lymphoma	COSMIC cancer mutations	Burkitt_lymphoma	2119	19	16828	49	MAML2,GLI3,NKAIN3,SLC1A3,PCDH9,SPON1,FBXL7,BMPR1B,NHSL1,NPAS3,ATP13A4,CPE,GPC5,LSAMP,PREX2,SLC1A2,CTNND2,GPM6A,RYR3
3.226e-06	-12.64	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-Burkitt_lymphoma	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-Burkitt_lymphoma	2119	19	16828	49	BMPR1B,FBXL7,PCDH9,SPON1,NKAIN3,SLC1A3,GLI3,MAML2,RYR3,GPM6A,CTNND2,SLC1A2,PREX2,LSAMP,GPC5,ATP13A4,CPE,NPAS3,NHSL1
3.494e-06	-12.56	acute_myeloid_leukaemia_therapy_related	COSMIC cancer mutations	acute_myeloid_leukaemia_therapy_related	1523	16	16828	49	GLI3,PCDH9,SPON1,NKAIN3,SLC1A3,COL5A3,ACSS1,FBXL7,MAML2,GPC5,LSAMP,PREX2,RYR3,CTNND2,MEIS2,QKI
3.494e-06	-12.56	haematopoietic_and_lymphoid_tissue-haematopoietic_neoplasm-acute_myeloid_leukaemia_therapy_related	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue-haematopoietic_neoplasm-acute_myeloid_leukaemia_therapy_related	1523	16	16828	49	MEIS2,QKI,GPC5,LSAMP,PREX2,RYR3,CTNND2,MAML2,GLI3,PCDH9,SPON1,SLC1A3,NKAIN3,COL5A3,ACSS1,FBXL7
3.516e-06	-12.56	tibia	COSMIC cancer mutations	tibia	836	12	16828	49	LSAMP,PREX2,GPM6A,CTNND2,QKI,CPE,FGFR3,NDRG2,NKAIN3,ACSS1,MACF1,ABLIM1
3.650e-06	-12.52	MAPT (microtubule associated protein tau)	protein interactions	4137	948	12	19454	50	LSAMP,NTM,SORBS1,GPM6A,SLC1A2,CTNND2,CLU,SLC1A3,APOE,ABLIM1,CTNNA2,NDRG2
4.655e-06	-12.28	cell periphery	cellular component	GO:0071944	6020	31	19108	49	ATP13A4,CTNNA2,GPC5,AQP4,PARD3B,SPARCL1,NKAIN3,CDH20,RYR3,PTPRZ1,CTNND2,DTNA,MACF1,LSAMP,GPM6A,FGFR3,SLC4A4,BMPR1B,PCDH9,CLU,CST3,PON2,APOE,PREX2,SLC1A3,SLC1A2,SPON1,NTM,COL5A3,SORBS1,CPE
4.679e-06	-12.27	cell junction	cellular component	GO:0030054	2224	18	19108	49	CDH20,SLC1A3,PTPRZ1,SLC1A2,CTNND2,DTNA,NFIA,GPM6A,FGFR3,SORBS1,PCDH9,CLU,CTNNA2,QKI,APOE,ARHGAP24,SPARCL1,PARD3B
4.871e-06	-12.23	diffuse_large_B_cell_lymphoma	COSMIC cancer mutations	diffuse_large_B_cell_lymphoma	4151	27	16828	49	SPON1,SLC1A3,MACF1,RYR3,SLC1A2,CTNND2,LSAMP,GPC5,SPARCL1,CPE,ATP13A4,AQP4,QKI,MEIS2,ACSS1,FBXL7,PCDH9,NKAIN3,GLI3,FGFR3,CLU,DTNA,MAML2,GPM6A,PREX2,TRPS1,CDH20
5.357e-06	-12.14	angiosarcoma	COSMIC cancer mutations	angiosarcoma	2192	19	16828	49	CDH20,ARHGAP24,MEIS2,GPC5,RYR3,GPM6A,CTNND2,SLC1A2,PREX2,LSAMP,MAML2,PCDH9,SPON1,SLC1A3,NKAIN3,GLI3,PTPRZ1,COL5A3,FBXL7
5.357e-06	-12.14	soft_tissue-blood_vessel-angiosarcoma	COSMIC cancer mutations	soft_tissue-blood_vessel-angiosarcoma	2192	19	16828	49	GLI3,PTPRZ1,PCDH9,SPON1,SLC1A3,NKAIN3,COL5A3,FBXL7,MAML2,GPC5,LSAMP,PREX2,RYR3,GPM6A,SLC1A2,CTNND2,ARHGAP24,CDH20,MEIS2
7.388e-06	-11.82	pharynx	COSMIC cancer mutations	pharynx	2696	21	16828	49	NHSL1,NPAS3,ATP13A4,QKI,SLC4A4,PARD3B,NFIA,GPC5,PREX2,RYR3,SLC1A2,CTNND2,SORBS1,PITPNC1,MACF1,CLU,DTNA,FGFR3,PTPRZ1,PCDH9,AMZ2
8.073e-06	-11.73	haematopoietic_and_lymphoid_tissue-lymph_node-lymphoid_neoplasm-mantle_cell_lymphoma	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue-lymph_node-lymphoid_neoplasm-mantle_cell_lymphoma	476	9	16828	49	ATP13A4,MAML2,MEIS2,RYR3,GPM6A,CTNND2,LSAMP,GPC5,PCDH9
8.240e-06	-11.71	adherens junction	cellular component	GO:0005912	188	6	19108	49	CTNND2,SORBS1,CTNNA2,ARHGAP24,PARD3B,CDH20
9.341e-06	-11.58	anatomical structure morphogenesis	biological process	GO:0009653	2225	18	18204	49	BMPR1B,QKI,FGFR3,NFIA,PREX2,CTNNA2,ABLIM1,MEIS2,GPM6A,GLI3,CLU,ARHGAP24,SLC1A3,CTNND2,APOE,PTPRZ1,CPE,CDH20
1.097e-05	-11.42	chronic_lymphocytic_leukaemia-small_lymphocytic_lymphoma	COSMIC cancer mutations	chronic_lymphocytic_leukaemia-small_lymphocytic_lymphoma	3511	24	16828	49	GPC5,RYR3,CTNND2,LSAMP,CPE,SLC4A4,NPAS3,MEIS2,SPON1,SLC1A3,PTPRZ1,BMPR1B,PITPNC1,MACF1,PARD3B,PREX2,MSI2,PAMR1,PCDH9,AMZ2,GLI3,FBXL7,CLU,DTNA
1.097e-05	-11.42	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-chronic_lymphocytic_leukaemia-small_lymphocytic_lymphoma	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-chronic_lymphocytic_leukaemia-small_lymphocytic_lymphoma	3511	24	16828	49	GLI3,PCDH9,AMZ2,FBXL7,CLU,DTNA,PARD3B,PREX2,PAMR1,MSI2,PTPRZ1,SPON1,SLC1A3,BMPR1B,PITPNC1,MACF1,GPC5,LSAMP,RYR3,CTNND2,NPAS3,MEIS2,CPE,SLC4A4
1.167e-05	-11.36	system development	biological process	GO:0048731	3533	23	18204	49	CTNNA2,GPM6A,MEIS2,PCDH9,GLI3,NTM,BMPR1B,SLC1A2,PREX2,FGFR3,NDRG2,NFIA,QKI,LSAMP,SLC1A3,APOE,TRPS1,CTNND2,CPE,PTPRZ1,CLU,MSI2,ARHGAP24
1.310e-05	-11.24	central_nervous_system-brain-primitive_neuroectodermal_tumour-medulloblastoma	COSMIC cancer mutations	central_nervous_system-brain-primitive_neuroectodermal_tumour-medulloblastoma	7205	36	16828	49	NHSL1,PAMR1,GPM6A,SORBS1,PREX2,NFIA,TRPS1,PARD3B,ABLIM1,MAML2,PON2,COL5A3,ACSS1,FBXL7,PCDH9,NKAIN3,GLI3,FGFR3,CPE,ATP13A4,QKI,SLC4A4,NPAS3,MEIS2,NTM,RYR3,CTNND2,SLC1A2,LSAMP,GPC5,MACF1,PITPNC1,GLIS3,SPON1,SLC1A3,PTPRZ1
1.425e-05	-11.16	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-acute_lymphoblastic_B_cell_leukaemia	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-acute_lymphoblastic_B_cell_leukaemia	3828	25	16828	49	GLIS3,BMPR1B,PTPRZ1,SPON1,SLC1A3,MEIS2,CPE,ATP13A4,SLC4A4,NTM,LSAMP,RYR3,CTNND2,SLC1A2,GPC5,MAML2,COL5A3,FBXL7,GLI3,PCDH9,NKAIN3,PAMR1,PREX2,GPM6A,NFIA
1.425e-05	-11.16	acute_lymphoblastic_B_cell_leukaemia	COSMIC cancer mutations	acute_lymphoblastic_B_cell_leukaemia	3828	25	16828	49	MAML2,COL5A3,FBXL7,PCDH9,NKAIN3,GLI3,PAMR1,GPM6A,PREX2,NFIA,BMPR1B,GLIS3,SPON1,SLC1A3,PTPRZ1,CPE,ATP13A4,SLC4A4,MEIS2,NTM,RYR3,SLC1A2,CTNND2,LSAMP,GPC5
1.468e-05	-11.13	lymph_node	COSMIC cancer mutations	lymph_node	1703	16	16828	49	TRPS1,GPC5,PARD3B,CTNND2,GPM6A,RYR3,LSAMP,ARHGAP24,ATP13A4,MEIS2,SLC1A3,PCDH9,FGFR3,ACSS1,DTNA,MAML2
1.509e-05	-11.10	central_nervous_system-cerebellum-primitive_neuroectodermal_tumour-medulloblastoma-SHH_subtype	COSMIC cancer mutations	central_nervous_system-cerebellum-primitive_neuroectodermal_tumour-medulloblastoma-SHH_subtype	653	10	16828	49	MAML2,NPAS3,MEIS2,ABLIM1,CPE,CTNND2,RYR3,PTPRZ1,PARD3B,PCDH9
1.529e-05	-11.09	SHH_subtype	COSMIC cancer mutations	SHH_subtype	654	10	16828	49	RYR3,CTNND2,PCDH9,PARD3B,PTPRZ1,CPE,ABLIM1,MAML2,NPAS3,MEIS2
1.782e-05	-10.94	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-diffuse_large_B_cell_lymphoma	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-diffuse_large_B_cell_lymphoma	3608	24	16828	49	MAML2,CLU,FGFR3,GLI3,NKAIN3,PCDH9,ACSS1,FBXL7,CDH20,PREX2,GPM6A,MACF1,SPON1,MEIS2,ATP13A4,AQP4,QKI,CPE,SPARCL1,GPC5,LSAMP,CTNND2,SLC1A2,RYR3
1.847e-05	-10.90	brainstem	COSMIC cancer mutations	brainstem	3102	22	16828	49	CDH20,PREX2,GPM6A,MAML2,FBXL7,FGFR3,GLI3,NKAIN3,PCDH9,MEIS2,NPAS3,QKI,ATP13A4,CPE,LSAMP,CTNND2,SLC1A2,RYR3,GPC5,PTPRZ1,SLC1A3,SPON1
2.276e-05	-10.69	multicellular organism development	biological process	GO:0007275	3957	24	18204	49	CTNNA2,GPM6A,GLI3,SLC1A2,NDRG2,QKI,PREX2,SLC1A3,TRPS1,CPE,CDH20,CLU,MSI2,MEIS2,PCDH9,NTM,BMPR1B,FGFR3,NFIA,LSAMP,CTNND2,APOE,PTPRZ1,ARHGAP24
3.199e-05	-10.35	cell adhesion	biological process	GO:0007155	942	11	18204	49	COL5A3,NTM,SPON1,PCDH9,CDH20,CTNNA2,LSAMP,SPARCL1,CTNND2,SORBS1,PARD3B
3.599e-05	-10.23	neurogenesis	biological process	GO:0022008	1334	13	18204	49	GLI3,CTNNA2,GPM6A,QKI,NFIA,PREX2,NTM,BMPR1B,PTPRZ1,SLC1A3,CTNND2,APOE,CLU
4.330e-05	-10.05	central_nervous_system-brainstem-glioma-astrocytoma_Grade_IV	COSMIC cancer mutations	central_nervous_system-brainstem-glioma-astrocytoma_Grade_IV	2531	19	16828	49	FBXL7,SPON1,PCDH9,SLC1A3,NKAIN3,GLI3,PTPRZ1,MAML2,GPM6A,RYR3,CTNND2,LSAMP,PREX2,GPC5,ATP13A4,CPE,QKI,MEIS2,CDH20
4.917e-05	-9.92	Neurotransmitter uptake and Metabolism In Glial Cells	REACTOME pathways	R-HSA-112313	4	2	10285	30	SLC1A3,SLC1A2
4.917e-05	-9.92	Astrocytic Glutamate-Glutamine Uptake And Metabolism	REACTOME pathways	R-HSA-210455	4	2	10285	30	SLC1A2,SLC1A3
5.275e-05	-9.85	central nervous system development	biological process	GO:0007417	995	11	18204	49	CLU,NDRG2,QKI,MSI2,BMPR1B,SLC1A2,PTPRZ1,PCDH9,GLI3,CTNNA2,MEIS2
5.762e-05	-9.76	haematopoietic_and_lymphoid_tissue-haematopoietic_neoplasm	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue-haematopoietic_neoplasm	764	10	16828	49	MAML2,NKAIN3,GPC5,PCDH9,SLC1A2,RYR3,FBXL7,LSAMP,COL5A3,PREX2
6.151e-05	-9.70	rhabdomyosarcoma	COSMIC cancer mutations	rhabdomyosarcoma	4150	25	16828	49	NPAS3,AQP4,RYR3,CTNND2,SPARCL1,MACF1,GLIS3,PTPRZ1,SPON1,SLC1A3,NHSL1,PAMR1,CDH20,PREX2,SORBS1,PARD3B,NFIA,TRPS1,MAML2,PON2,CLU,APOE,COL5A3,GLI3,FGFR3
6.375e-05	-9.66	negative regulation of amyloid-beta formation	biological process	GO:1902430	29	3	18204	49	SPON1,CLU,APOE
6.535e-05	-9.64	mantle_cell_lymphoma	COSMIC cancer mutations	mantle_cell_lymphoma	2849	20	16828	49	SLC1A2,CTNND2,GPM6A,RYR3,LSAMP,PREX2,TRPS1,GPC5,PARD3B,ATP13A4,CPE,MEIS2,ARHGAP24,FBXL7,SLC1A3,NKAIN3,SPON1,PCDH9,GLI3,MAML2
6.856e-05	-9.59	high-affinity L-glutamate transmembrane transporter activity	molecular function	GO:0005314	5	2	18094	48	SLC1A3,SLC1A2
6.856e-05	-9.59	glutamate:sodium symporter activity	molecular function	GO:0015501	5	2	18094	48	SLC1A2,SLC1A3
7.061e-05	-9.56	D-aspartate transmembrane transport	biological process	GO:0070777	5	2	18204	49	SLC1A3,SLC1A2
7.061e-05	-9.56	positive regulation of amyloid fibril formation	biological process	GO:1905908	5	2	18204	49	CLU,APOE
7.061e-05	-9.56	D-aspartate import across plasma membrane	biological process	GO:0070779	5	2	18204	49	SLC1A3,SLC1A2
7.813e-05	-9.46	negative regulation of amyloid precursor protein catabolic process	biological process	GO:1902992	31	3	18204	49	APOE,CLU,SPON1
7.981e-05	-9.44	neuron development	biological process	GO:0048666	859	10	18204	49	GLI3,PTPRZ1,CTNND2,GPM6A,APOE,SLC1A3,CTNNA2,PREX2,BMPR1B,NTM
8.255e-05	-9.40	NTM (neurotrimin)	protein interactions	50863	33	3	19454	50	NTM,GPM6A,LSAMP
8.334e-05	-9.39	soft_tissue-striated_muscle-rhabdomyosarcoma-alveolar	COSMIC cancer mutations	soft_tissue-striated_muscle-rhabdomyosarcoma-alveolar	2414	18	16828	49	NPAS3,NHSL1,PAMR1,CDH20,PREX2,RYR3,SORBS1,PARD3B,NFIA,TRPS1,SPARCL1,MACF1,PON2,CLU,APOE,FGFR3,SPON1,SLC1A3
8.334e-05	-9.39	alveolar	COSMIC cancer mutations	alveolar	2414	18	16828	49	NHSL1,PAMR1,CDH20,NPAS3,NFIA,TRPS1,SPARCL1,PARD3B,RYR3,SORBS1,PREX2,APOE,CLU,MACF1,PON2,SPON1,SLC1A3,FGFR3
8.349e-05	-9.39	multicellular organismal process	biological process	GO:0032501	6177	30	18204	49	ARHGAP24,LSAMP,PTGDS,APOE,CTNND2,PTPRZ1,NTM,BMPR1B,SLC4A4,FGFR3,NFIA,ABLIM1,MEIS2,DTNA,PCDH9,CLU,MSI2,SLC1A3,TRPS1,CPE,CDH20,SLC1A2,PREX2,AQP4,QKI,NDRG2,CTNNA2,GPM6A,RYR3,GLI3
8.544e-05	-9.37	striated_muscle	COSMIC cancer mutations	striated_muscle	4228	25	16828	49	SORBS1,PREX2,NFIA,TRPS1,PARD3B,NHSL1,CDH20,PAMR1,COL5A3,FGFR3,GLI3,CLU,MAML2,PON2,APOE,RYR3,CTNND2,SPARCL1,AQP4,NPAS3,GLIS3,SPON1,SLC1A3,PTPRZ1,MACF1
8.642e-05	-9.36	embryonal	COSMIC cancer mutations	embryonal	2659	19	16828	49	PARD3B,NFIA,SPARCL1,PREX2,RYR3,SORBS1,CTNND2,NPAS3,AQP4,FGFR3,GLI3,PTPRZ1,SPON1,COL5A3,GLIS3,APOE,MACF1,MAML2,PON2
8.642e-05	-9.36	soft_tissue-striated_muscle-rhabdomyosarcoma-embryonal	COSMIC cancer mutations	soft_tissue-striated_muscle-rhabdomyosarcoma-embryonal	2659	19	16828	49	APOE,PON2,MAML2,MACF1,PTPRZ1,GLI3,FGFR3,SPON1,GLIS3,COL5A3,NPAS3,AQP4,PARD3B,SPARCL1,NFIA,PREX2,CTNND2,SORBS1,RYR3
8.887e-05	-9.33	anatomical structure development	biological process	GO:0048856	5207	27	18204	49	SLC1A3,TRPS1,CPE,CDH20,CLU,MSI2,CTNNA2,SPARCL1,GPM6A,GLI3,SLC1A2,NDRG2,QKI,PREX2,LSAMP,CTNND2,APOE,PTPRZ1,COL5A3,ARHGAP24,ABLIM1,MEIS2,PCDH9,NTM,BMPR1B,FGFR3,NFIA
1.027e-04	-9.18	collagen-containing extracellular matrix	cellular component	GO:0062023	428	7	19108	49	CLU,APOE,PTPRZ1,SPON1,SPARCL1,COL5A3,GPC5
1.034e-04	-9.18	negative regulation of amide metabolic process	biological process	GO:0034249	34	3	18204	49	APOE,CLU,SPON1
1.057e-04	-9.15	L-aspartate import across plasma membrane	biological process	GO:0140009	6	2	18204	49	SLC1A2,SLC1A3
1.057e-04	-9.15	D-amino acid transport	biological process	GO:0042940	6	2	18204	49	SLC1A2,SLC1A3
1.064e-04	-9.15	GLI-like	interpro domains	IPR043359	6	2	18521	50	GLIS3,GLI3
1.080e-04	-9.13	autonomic_ganglia	COSMIC cancer mutations	autonomic_ganglia	4005	24	16828	49	NHSL1,NFIA,TRPS1,PARD3B,GPM6A,PREX2,MAML2,PCDH9,AMZ2,GLI3,FGFR3,COL5A3,FBXL7,ACSS1,AQP4,SLC4A4,NPAS3,RYR3,CTNND2,SLC1A2,PITPNC1,MACF1,PTPRZ1,GLIS3
1.112e-04	-9.10	neuron differentiation	biological process	GO:0030182	1081	11	18204	49	GPM6A,CTNNA2,GLI3,BMPR1B,NTM,PREX2,NFIA,APOE,CTNND2,SLC1A3,PTPRZ1
1.139e-04	-9.08	plasma membrane	cellular component	GO:0005886	5538	27	19108	49	PARD3B,AQP4,CTNNA2,ATP13A4,GPC5,BMPR1B,LSAMP,FGFR3,SLC4A4,GPM6A,MACF1,CTNND2,DTNA,RYR3,NKAIN3,CDH20,PTPRZ1,PREX2,APOE,CST3,PCDH9,PON2,SORBS1,CPE,NTM,SLC1A2,SLC1A3
1.287e-04	-8.96	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-mantle_cell_lymphoma	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-mantle_cell_lymphoma	2737	19	16828	49	PCDH9,SPON1,NKAIN3,SLC1A3,GLI3,FBXL7,MAML2,GPC5,TRPS1,PARD3B,GPM6A,RYR3,SLC1A2,CTNND2,LSAMP,PREX2,ARHGAP24,CPE,MEIS2
1.399e-04	-8.87	endoplasmic reticulum lumen	cellular component	GO:0005788	312	6	19108	49	COL5A3,SPON1,SPARCL1,APOE,CLU,CST3
1.462e-04	-8.83	ductolobular_carcinoma	COSMIC cancer mutations	ductolobular_carcinoma	1619	14	16828	49	MACF1,ABLIM1,DTNA,FGFR3,GLI3,NDRG2,PTPRZ1,CDH20,CPE,QKI,PARD3B,PREX2,CTNND2,SORBS1
1.462e-04	-8.83	breast-carcinoma-ductolobular_carcinoma	COSMIC cancer mutations	breast-carcinoma-ductolobular_carcinoma	1619	14	16828	49	PARD3B,PREX2,CTNND2,SORBS1,CDH20,CPE,QKI,GLI3,FGFR3,NDRG2,PTPRZ1,MACF1,ABLIM1,DTNA
1.469e-04	-8.83	HUNK (hormonally up-regulated Neu-associated kinase)	protein interactions	30811	104	4	19454	50	SORBS1,SPARCL1,CLU,ABLIM1
1.487e-04	-8.81	Na:dicarbo_symporter_sf	interpro domains	IPR036458	7	2	18521	50	SLC1A3,SLC1A2
1.487e-04	-8.81	Na-dicarboxylate_symporter	interpro domains	IPR001991	7	2	18521	50	SLC1A2,SLC1A3
1.487e-04	-8.81	Na-dicarboxylate_symporter_CS	interpro domains	IPR018107	7	2	18521	50	SLC1A3,SLC1A2
1.565e-04	-8.76	cellular response to alkaloid	biological process	GO:0071312	39	3	18204	49	RYR3,SLC1A2,SLC1A3
1.610e-04	-8.73	SDF	pfam domains	PF00375	7	2	17795	50	SLC1A3,SLC1A2
1.687e-04	-8.69	developmental process	biological process	GO:0032502	5716	28	18204	49	SLC1A3,TRPS1,CPE,CDH20,CLU,MSI2,CTNNA2,SPARCL1,GPM6A,GLI3,SLC1A2,QKI,NDRG2,PREX2,LSAMP,CTNND2,APOE,PTPRZ1,COL5A3,ARHGAP24,ABLIM1,NHSL1,MEIS2,PCDH9,NTM,BMPR1B,FGFR3,NFIA
1.712e-04	-8.67	cell morphogenesis involved in neuron differentiation	biological process	GO:0048667	443	7	18204	49	PREX2,BMPR1B,PTPRZ1,GLI3,CTNNA2,SLC1A3,CTNND2
1.776e-04	-8.64	CTNNA1 (catenin alpha 1)	protein interactions	1495	325	6	19454	50	DTNA,ABLIM1,MACF1,CTNNA2,SORBS1,NHSL1
1.841e-04	-8.60	beta-catenin binding	molecular function	GO:0008013	107	4	18094	48	CDH20,CTNND2,CTNNA2,GLI3
1.874e-04	-8.58	bone-tibia-other-chondroblastoma	COSMIC cancer mutations	bone-tibia-other-chondroblastoma	98	4	16828	49	NKAIN3,CTNND2,GPM6A,LSAMP
1.879e-04	-8.58	Sodium:dicarboxylate symporter	gene3d domains	1.10.3860.10	7	2	14470	44	SLC1A2,SLC1A3
1.967e-04	-8.53	protein import	biological process	GO:0017038	8	2	18204	49	CLU,APOE
2.035e-04	-8.50	cell projection	cellular component	GO:0042995	2398	16	19108	49	ARHGAP24,APOE,AQP4,NDRG2,CTNNA2,ABLIM1,PCDH9,CLU,BMPR1B,GPM6A,MACF1,DTNA,CTNND2,SLC1A2,GLI3,SLC1A3
2.040e-04	-8.50	generation of neurons	biological process	GO:0048699	1158	11	18204	49	GPM6A,CTNNA2,GLI3,BMPR1B,NTM,PREX2,NFIA,APOE,CTNND2,SLC1A3,PTPRZ1
2.304e-04	-8.38	KLB (klotho beta)	protein interactions	152831	9	2	19454	50	FGFR3,ARHGAP24
2.304e-04	-8.38	LSAMP (limbic system associated membrane protein)	protein interactions	4045	9	2	19454	50	NTM,LSAMP
2.304e-04	-8.38	NEGR1 (neuronal growth regulator 1)	protein interactions	257194	9	2	19454	50	LSAMP,NTM
2.409e-04	-8.33	NA_DICARBOXYL_SYMP_1	prosite domains	PS00713	7	2	12186	42	SLC1A2,SLC1A3
2.409e-04	-8.33	NA_DICARBOXYL_SYMP_2	prosite domains	PS00714	7	2	12186	42	SLC1A2,SLC1A3
2.888e-04	-8.15	EDTRNSPORT	prints domains	PR00173	7	2	5227	20	SLC1A2,SLC1A3
2.894e-04	-8.15	autonomic_ganglia-neuroblastoma	COSMIC cancer mutations	autonomic_ganglia-neuroblastoma	3970	23	16828	49	NPAS3,SLC4A4,AQP4,PARD3B,TRPS1,NFIA,PREX2,SLC1A2,CTNND2,GPM6A,RYR3,PITPNC1,MACF1,MAML2,PTPRZ1,GLI3,FGFR3,AMZ2,PCDH9,ACSS1,GLIS3,FBXL7,COL5A3
2.905e-04	-8.14	neuroblastoma	COSMIC cancer mutations	neuroblastoma	3971	23	16828	49	MAML2,COL5A3,ACSS1,FBXL7,FGFR3,GLI3,PCDH9,AMZ2,PREX2,GPM6A,PARD3B,NFIA,TRPS1,MACF1,PITPNC1,GLIS3,PTPRZ1,NPAS3,AQP4,SLC4A4,RYR3,SLC1A2,CTNND2
2.909e-04	-8.14	nodular	COSMIC cancer mutations	nodular	1515	13	16828	49	SPARCL1,PREX2,CTNND2,CDH20,NPAS3,SLC4A4,ATP13A4,CPE,PTPRZ1,FGFR3,GLIS3,MACF1,ABLIM1
2.911e-04	-8.14	regulation of amyloid-beta formation	biological process	GO:1902003	48	3	18204	49	APOE,CLU,SPON1
2.984e-04	-8.12	glial cell differentiation	biological process	GO:0010001	219	5	18204	49	CLU,QKI,NFIA,PTPRZ1,GLI3
3.013e-04	-8.11	neuron projection morphogenesis	biological process	GO:0048812	486	7	18204	49	GPM6A,CTNND2,CTNNA2,GLI3,PTPRZ1,BMPR1B,PREX2
3.121e-04	-8.07	cell-cell junction	cellular component	GO:0005911	513	7	19108	49	PCDH9,CDH20,CTNNA2,CTNND2,PARD3B,ARHGAP24,SORBS1
3.150e-04	-8.06	cellular response to cocaine	biological process	GO:0071314	10	2	18204	49	SLC1A3,SLC1A2
3.162e-04	-8.06	PAX9 (paired box 9)	protein interactions	5083	127	4	19454	50	QKI,TRPS1,NFIA,ARHGAP24
3.205e-04	-8.05	plasma membrane bounded cell projection morphogenesis	biological process	GO:0120039	491	7	18204	49	PTPRZ1,PREX2,GLI3,CTNNA2,CTNND2,GPM6A,BMPR1B
3.234e-04	-8.04	upper_aerodigestive_tract-mouth-carcinoma	COSMIC cancer mutations	upper_aerodigestive_tract-mouth-carcinoma	6426	31	16828	49	FGFR3,GLI3,AMZ2,FBXL7,ACSS1,COL5A3,APOE,MAML2,CLU,ABLIM1,PARD3B,TRPS1,PREX2,SORBS1,GPM6A,CDH20,PAMR1,NHSL1,NDRG2,SLC1A3,SPON1,PITPNC1,MACF1,GPC5,CTNND2,SLC1A2,RYR3,NTM,NPAS3,SLC4A4,QKI
3.407e-04	-7.98	cell projection morphogenesis	biological process	GO:0048858	496	7	18204	49	BMPR1B,PREX2,GPM6A,CTNND2,CTNNA2,GLI3,PTPRZ1
3.844e-04	-7.86	L-glutamate import across plasma membrane	biological process	GO:0098712	11	2	18204	49	SLC1A3,SLC1A2
3.844e-04	-7.86	L-aspartate transmembrane transport	biological process	GO:0070778	11	2	18204	49	SLC1A3,SLC1A2
3.906e-04	-7.85	regulation of chondrocyte differentiation	biological process	GO:0032330	53	3	18204	49	BMPR1B,TRPS1,GLI3
4.023e-04	-7.82	CSTL1 (cystatin like 1)	protein interactions	128817	56	3	19454	50	CLU,APOE,CPE
4.129e-04	-7.79	plasma membrane bounded cell projection	cellular component	GO:0120025	2285	15	19108	49	APOE,AQP4,NDRG2,CTNNA2,CLU,PCDH9,ABLIM1,BMPR1B,GPM6A,DTNA,CTNND2,MACF1,SLC1A2,GLI3,SLC1A3
4.203e-04	-7.77	TREM2 (triggering receptor expressed on myeloid cells 2)	protein interactions	54209	12	2	19454	50	CLU,APOE
4.357e-04	-7.74	regulation of amyloid precursor protein catabolic process	biological process	GO:1902991	55	3	18204	49	APOE,SPON1,CLU
4.466e-04	-7.71	neuron projection	cellular component	GO:0043005	1331	11	19108	49	APOE,PCDH9,CLU,NDRG2,CTNNA2,GPM6A,BMPR1B,SLC1A3,DTNA,CTNND2,SLC1A2
4.513e-04	-7.70	haematopoietic_and_lymphoid_tissue-haematopoietic_neoplasm-myelodysplastic_syndrome	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue-haematopoietic_neoplasm-myelodysplastic_syndrome	1174	11	16828	49	FGFR3,NKAIN3,NFIA,FBXL7,LSAMP,PREX2,COL5A3,SLC1A2,BMPR1B,RYR3,NPAS3
4.513e-04	-7.70	myelodysplastic_syndrome	COSMIC cancer mutations	myelodysplastic_syndrome	1174	11	16828	49	RYR3,SLC1A2,LSAMP,PREX2,NFIA,NPAS3,BMPR1B,COL5A3,FBXL7,NKAIN3,FGFR3
4.796e-04	-7.64	neuron projection development	biological process	GO:0031175	693	8	18204	49	PREX2,BMPR1B,GLI3,PTPRZ1,CTNND2,APOE,GPM6A,CTNNA2
5.187e-04	-7.56	cell junction organization	biological process	GO:0034330	532	7	18204	49	SPARCL1,APOE,GPM6A,SORBS1,CTNND2,CDH20,NFIA
5.199e-04	-7.56	CTNNB1 (catenin beta 1)	protein interactions	1499	926	9	19454	50	NHSL1,SORBS1,PTPRZ1,CTNND2,CTNNA2,PARD3B,ARHGAP24,DTNA,APOE
5.225e-04	-7.56	extracellular matrix	cellular component	GO:0031012	559	7	19108	49	SPARCL1,SPON1,GPC5,COL5A3,CLU,PTPRZ1,APOE
5.281e-04	-7.55	external encapsulating structure	cellular component	GO:0030312	560	7	19108	49	APOE,PTPRZ1,CLU,COL5A3,GPC5,SPON1,SPARCL1
5.432e-04	-7.52	negative regulation of amyloid fibril formation	biological process	GO:1905907	13	2	18204	49	APOE,CLU
5.776e-04	-7.46	C9 (complement C9)	protein interactions	735	14	2	19454	50	CLU,APOE
5.776e-04	-7.46	PLXNA4 (plexin A4)	protein interactions	91584	14	2	19454	50	GPM6A,CLU
5.776e-04	-7.46	CTSO (cathepsin O)	protein interactions	1519	14	2	19454	50	CST3,AMZ2
6.145e-04	-7.39	L-glutamate transmembrane transporter activity	molecular function	GO:0005313	14	2	18094	48	SLC1A3,SLC1A2
6.239e-04	-7.38	upper_aerodigestive_tract-pharynx-carcinoma-nasopharyngeal_carcinoma	COSMIC cancer mutations	upper_aerodigestive_tract-pharynx-carcinoma-nasopharyngeal_carcinoma	1425	12	16828	49	SLC4A4,CLU,QKI,ATP13A4,PITPNC1,NHSL1,SLC1A2,CTNND2,PREX2,AMZ2,NFIA,FGFR3
6.239e-04	-7.38	nasopharyngeal_carcinoma	COSMIC cancer mutations	nasopharyngeal_carcinoma	1425	12	16828	49	FGFR3,NFIA,AMZ2,PREX2,SLC1A2,CTNND2,NHSL1,PITPNC1,ATP13A4,CLU,QKI,SLC4A4
6.654e-04	-7.32	RNASE13 (ribonuclease A family member 13 (inactive))	protein interactions	440163	15	2	19454	50	CLU,CPE
6.803e-04	-7.29	dendrite morphogenesis	biological process	GO:0048813	64	3	18204	49	CTNND2,CTNNA2,PREX2
7.592e-04	-7.18	CNTNAP2 (contactin associated protein 2)	protein interactions	26047	16	2	19454	50	CPE,MACF1
8.133e-04	-7.11	carcinoid-endocrine_tumour	COSMIC cancer mutations	carcinoid-endocrine_tumour	7752	34	16828	49	COL5A3,ACSS1,FBXL7,PCDH9,NKAIN3,FGFR3,GLI3,CLU,ABLIM1,MAML2,PON2,APOE,GPM6A,PREX2,TRPS1,NHSL1,CDH20,PAMR1,BMPR1B,GLIS3,SPON1,SLC1A3,PTPRZ1,MACF1,RYR3,CTNND2,SLC1A2,LSAMP,GPC5,ATP13A4,QKI,CPE,SLC4A4,MEIS2
8.340e-04	-7.09	plasma_cell_myeloma	COSMIC cancer mutations	plasma_cell_myeloma	1263	11	16828	49	MACF1,ATP13A4,ABLIM1,NTM,PAMR1,GPM6A,RYR3,CTNND2,GLI3,FGFR3,TRPS1
8.340e-04	-7.09	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-plasma_cell_myeloma	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-plasma_cell_myeloma	1263	11	16828	49	MACF1,ABLIM1,ATP13A4,NTM,PAMR1,CTNND2,GPM6A,RYR3,FGFR3,GLI3,TRPS1
8.403e-04	-7.08	gliogenesis	biological process	GO:0042063	275	5	18204	49	CLU,PTPRZ1,NFIA,QKI,GLI3
8.422e-04	-7.08	chondroblastoma	COSMIC cancer mutations	chondroblastoma	534	7	16828	49	RYR3,GPM6A,CTNND2,LSAMP,GPC5,PCDH9,NKAIN3
8.516e-04	-7.07	spindle	COSMIC cancer mutations	spindle	386	6	16828	49	PREX2,MACF1,CTNND2,CPE,FGFR3,PCDH9
8.681e-04	-7.05	lymphoid_neoplasm	COSMIC cancer mutations	lymphoid_neoplasm	12233	45	16828	49	TRPS1,NFIA,PARD3B,SORBS1,GPM6A,PREX2,CDH20,PAMR1,MSI2,NHSL1,ARHGAP24,NKAIN3,AMZ2,PCDH9,GLI3,FGFR3,ACSS1,FBXL7,COL5A3,DTNA,CLU,ABLIM1,PON2,MAML2,SPARCL1,GPC5,CTNND2,SLC1A2,RYR3,LSAMP,NTM,SLC4A4,QKI,ATP13A4,CPE,AQP4,MEIS2,NPAS3,SLC1A3,SPON1,PTPRZ1,BMPR1B,GLIS3,PITPNC1,MACF1
9.407e-04	-6.97	regulation of amyloid fibril formation	biological process	GO:1905906	17	2	18204	49	CLU,APOE
9.407e-04	-6.97	reverse cholesterol transport	biological process	GO:0043691	17	2	18204	49	CLU,APOE
9.985e-04	-6.91	regulation of cartilage development	biological process	GO:0061035	73	3	18204	49	BMPR1B,TRPS1,GLI3
9.998e-04	-6.91	skin-trunk-malignant_melanoma-nodular	COSMIC cancer mutations	skin-trunk-malignant_melanoma-nodular	1291	11	16828	49	PREX2,GLIS3,CTNND2,PTPRZ1,SPARCL1,MACF1,NPAS3,CPE,ATP13A4,ABLIM1,CDH20
1.022e-03	-6.89	Htt (huntingtin)	protein interactions	15194	77	3	19454	50	LSAMP,NTM,GPM6A
1.026e-03	-6.88	acidic amino acid transmembrane transporter activity	molecular function	GO:0015172	18	2	18094	48	SLC1A2,SLC1A3
1.069e-03	-6.84	oesophagus-carcinoma-squamous_cell_carcinoma	COSMIC cancer mutations	oesophagus-carcinoma-squamous_cell_carcinoma	6486	30	16828	49	ABLIM1,MAML2,FBXL7,COL5A3,PCDH9,FGFR3,GLI3,ARHGAP24,SORBS1,GPM6A,PREX2,TRPS1,PARD3B,MACF1,PITPNC1,BMPR1B,GLIS3,SPON1,PTPRZ1,NDRG2,SLC4A4,AQP4,CPE,ATP13A4,MEIS2,NPAS3,CTNND2,RYR3,SPARCL1,GPC5
1.071e-03	-6.84	astrocyte projection	cellular component	GO:0097449	19	2	19108	49	AQP4,SLC1A2
1.077e-03	-6.83	RIT2 (Ras like without CAAX 2)	protein interactions	6014	19	2	19454	50	ARHGAP24,DTNA
1.158e-03	-6.76	superficial_spreading	COSMIC cancer mutations	superficial_spreading	1110	10	16828	49	SORBS1,CTNND2,COL5A3,PREX2,FGFR3,GLI3,SLC4A4,ATP13A4,MACF1,NTM
1.179e-03	-6.74	regulation of amyloid-beta clearance	biological process	GO:1900221	19	2	18204	49	CLU,APOE
1.194e-03	-6.73	PDZD2 (PDZ domain containing 2)	protein interactions	23037	20	2	19454	50	CTNND2,CST3
1.196e-03	-6.73	cartilage development	biological process	GO:0051216	173	4	18204	49	BMPR1B,GLI3,FGFR3,NFIA
1.247e-03	-6.69	solute:sodium symporter activity	molecular function	GO:0015370	80	3	18094	48	SLC1A2,SLC1A3,SLC4A4
1.261e-03	-6.68	behavior	biological process	GO:0007610	619	7	18204	49	GLI3,PTPRZ1,MEIS2,APOE,SLC1A3,PREX2,SLC1A2
1.265e-03	-6.67	mouth	COSMIC cancer mutations	mouth	9004	37	16828	49	GPC5,LSAMP,RYR3,CTNND2,SLC1A2,NTM,NPAS3,ATP13A4,QKI,SLC4A4,PTPRZ1,NDRG2,SPON1,SLC1A3,PITPNC1,MACF1,PARD3B,TRPS1,PREX2,GPM6A,SORBS1,NHSL1,PAMR1,CDH20,FGFR3,GLI3,CST3,PCDH9,AMZ2,COL5A3,ACSS1,FBXL7,APOE,MAML2,ABLIM1,CLU,DTNA
1.307e-03	-6.64	positive regulation of chondrocyte differentiation	biological process	GO:0032332	20	2	18204	49	BMPR1B,GLI3
1.307e-03	-6.64	aspartate transmembrane transport	biological process	GO:0015810	20	2	18204	49	SLC1A3,SLC1A2
1.318e-03	-6.63	TENM1 (teneurin transmembrane protein 1)	protein interactions	10178	21	2	19454	50	SORBS1,MACF1
1.349e-03	-6.61	regulation of amide metabolic process	biological process	GO:0034248	81	3	18204	49	APOE,SPON1,CLU
1.398e-03	-6.57	pancreas-carcinoid-endocrine_tumour	COSMIC cancer mutations	pancreas-carcinoid-endocrine_tumour	7250	32	16828	49	GPM6A,PREX2,NHSL1,PAMR1,CDH20,PCDH9,NKAIN3,FGFR3,GLI3,COL5A3,ACSS1,FBXL7,APOE,CLU,ABLIM1,MAML2,PON2,GPC5,RYR3,CTNND2,SLC1A2,LSAMP,QKI,ATP13A4,CPE,SLC4A4,MEIS2,SPON1,SLC1A3,BMPR1B,GLIS3,MACF1
1.550e-03	-6.47	chondrocyte differentiation	biological process	GO:0002062	85	3	18204	49	BMPR1B,GLI3,FGFR3
1.550e-03	-6.47	oligodendrocyte differentiation	biological process	GO:0048709	85	3	18204	49	CLU,PTPRZ1,GLI3
1.570e-03	-6.46	upper_aerodigestive_tract-mouth-carcinoma-squamous_cell_carcinoma	COSMIC cancer mutations	upper_aerodigestive_tract-mouth-carcinoma-squamous_cell_carcinoma	6953	31	16828	49	GLI3,FGFR3,CST3,PCDH9,FBXL7,ACSS1,MAML2,DTNA,ABLIM1,PARD3B,TRPS1,PREX2,SORBS1,GPM6A,PAMR1,CDH20,NHSL1,PTPRZ1,NDRG2,SPON1,PITPNC1,MACF1,GPC5,LSAMP,CTNND2,SLC1A2,RYR3,NTM,SLC4A4,QKI,ATP13A4
1.582e-03	-6.45	TIMM10B (translocase of inner mitochondrial membrane 10B)	protein interactions	26515	23	2	19454	50	MSI2,MEIS2
1.582e-03	-6.45	Rbm38 (RNA binding motif protein 38)	protein interactions	56190	23	2	19454	50	QKI,MSI2
1.603e-03	-6.44	transport across blood-brain barrier	biological process	GO:0150104	86	3	18204	49	SLC1A3,SLC1A2,SLC4A4
1.603e-03	-6.44	vascular transport	biological process	GO:0010232	86	3	18204	49	SLC4A4,SLC1A2,SLC1A3
1.636e-03	-6.42	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm	7307	32	16828	49	PON2,MAML2,CLU,ABLIM1,FBXL7,ACSS1,COL5A3,GLI3,NKAIN3,PCDH9,CDH20,PAMR1,NHSL1,PREX2,GPM6A,PARD3B,MACF1,GLIS3,BMPR1B,PTPRZ1,SLC1A3,SPON1,MEIS2,ATP13A4,CPE,QKI,LSAMP,SLC1A2,CTNND2,RYR3,SPARCL1,GPC5
1.683e-03	-6.39	amino acid:sodium symporter activity	molecular function	GO:0005283	23	2	18094	48	SLC1A2,SLC1A3
1.696e-03	-6.38	amyloid-beta binding	molecular function	GO:0001540	89	3	18094	48	CST3,CLU,APOE
1.715e-03	-6.37	human chr17q24.2	chromosome location	human chr17q24.2	32	2	26134	50	PITPNC1,AMZ2
1.748e-03	-6.35	parathyroid-carcinoma	COSMIC cancer mutations	parathyroid-carcinoma	300	5	16828	49	MACF1,RYR3,GPC5,PAMR1,TRPS1
1.758e-03	-6.34	lung-right_lower_lobe-carcinoma-adenocarcinoma	COSMIC cancer mutations	lung-right_lower_lobe-carcinoma-adenocarcinoma	5692	27	16828	49	MACF1,SPON1,SLC1A3,PTPRZ1,NTM,ATP13A4,SLC4A4,NPAS3,MEIS2,GPC5,RYR3,CTNND2,LSAMP,CLU,DTNA,MAML2,NKAIN3,CST3,GLI3,COL5A3,FBXL7,CDH20,PAMR1,TRPS1,PARD3B,GPM6A,SORBS1
1.758e-03	-6.34	right_lower_lobe	COSMIC cancer mutations	right_lower_lobe	5692	27	16828	49	ATP13A4,SLC4A4,NPAS3,MEIS2,NTM,RYR3,CTNND2,LSAMP,GPC5,MACF1,SPON1,SLC1A3,PTPRZ1,CDH20,PAMR1,GPM6A,SORBS1,TRPS1,PARD3B,CLU,DTNA,MAML2,COL5A3,FBXL7,NKAIN3,GLI3,CST3
1.832e-03	-6.30	low-density lipoprotein particle receptor binding	molecular function	GO:0050750	24	2	18094	48	CLU,APOE
1.912e-03	-6.26	SOX2 (SRY-box transcription factor 2)	protein interactions	6657	1342	10	19454	50	NFIA,CLU,LSAMP,QKI,MEIS2,TRPS1,GLIS3,GLI3,MACF1,MSI2
1.913e-03	-6.26	human chr15q13.3-q14	chromosome location	human chr15q13.3-q14	1	1	26134	50	RYR3
1.913e-03	-6.26	human chr4q21.23-q21.3	chromosome location	human chr4q21.23-q21.3	1	1	26134	50	ARHGAP24
1.928e-03	-6.25	anchoring junction	cellular component	GO:0070161	902	8	19108	49	CDH20,PCDH9,CTNNA2,CTNND2,FGFR3,ARHGAP24,PARD3B,SORBS1
1.960e-03	-6.23	synapse organization	biological process	GO:0050808	333	5	18204	49	NFIA,CTNND2,GPM6A,APOE,SPARCL1
2.013e-03	-6.21	high-density lipoprotein particle	cellular component	GO:0034364	26	2	19108	49	APOE,CLU
2.021e-03	-6.20	skin-face-malignant_melanoma-lentigo_maligna	COSMIC cancer mutations	skin-face-malignant_melanoma-lentigo_maligna	23	2	16828	49	FGFR3,PREX2
2.023e-03	-6.20	CYP2C18 (cytochrome P450 family 2 subfamily C member 18)	protein interactions	1562	26	2	19454	50	AMZ2,APOE
2.047e-03	-6.19	positive regulation of amyloid precursor protein catabolic process	biological process	GO:1902993	25	2	18204	49	CLU,SPON1
2.047e-03	-6.19	L-glutamate transmembrane transport	biological process	GO:0015813	25	2	18204	49	SLC1A2,SLC1A3
2.118e-03	-6.16	regulation of Wnt signaling pathway	biological process	GO:0030111	339	5	18204	49	GPC5,CTNND2,MACF1,APOE,GLI3
2.152e-03	-6.14	extrinsic component of plasma membrane	cellular component	GO:0019897	100	3	19108	49	DTNA,CTNNA2,CDH20
2.181e-03	-6.13	KCNJ12 (potassium inwardly rectifying channel subfamily J member 12)	protein interactions	3768	27	2	19454	50	DTNA,ABLIM1
2.181e-03	-6.13	HPCAL4 (hippocalcin like 4)	protein interactions	51440	27	2	19454	50	GPM6A,AQP4
2.181e-03	-6.13	MBNL2 (muscleblind like splicing regulator 2)	protein interactions	10150	27	2	19454	50	MSI2,QKI
2.181e-03	-6.13	Glutamate Neurotransmitter Release Cycle	REACTOME pathways	R-HSA-210500	24	2	10285	30	SLC1A2,SLC1A3
2.214e-03	-6.11	C4-dicarboxylate transport	biological process	GO:0015740	26	2	18204	49	SLC1A2,SLC1A3
2.247e-03	-6.10	PROKAR_LIPOPROTEIN	prosite domains	PS51257	76	3	12186	42	CPE,APOE,GLIS3
2.304e-03	-6.07	oesophagus-carcinoma	COSMIC cancer mutations	oesophagus-carcinoma	4269	22	16828	49	SLC4A4,PTGDS,ATP13A4,NTM,CDH20,NHSL1,PREX2,SORBS1,CTNND2,GPM6A,RYR3,PARD3B,TRPS1,NFIA,MACF1,ACSS1,FBXL7,COL5A3,PTPRZ1,GLI3,FGFR3,PCDH9
2.398e-03	-6.03	bone morphogenesis	biological process	GO:0060349	99	3	18204	49	FGFR3,GLI3,BMPR1B
2.412e-03	-6.03	haematopoietic_and_lymphoid_tissue-spleen-lymphoid_neoplasm-marginal_zone_lymphoma	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue-spleen-lymphoid_neoplasm-marginal_zone_lymphoma	323	5	16828	49	SORBS1,MEIS2,PARD3B,PTPRZ1,NTM
2.447e-03	-6.01	bone	COSMIC cancer mutations	bone	8157	34	16828	49	SLC4A4,QKI,CPE,ATP13A4,NPAS3,SPARCL1,GPC5,CTNND2,RYR3,LSAMP,MACF1,SLC1A3,SPON1,PTPRZ1,NDRG2,GLIS3,PAMR1,PTGDS,TRPS1,PARD3B,SORBS1,GPM6A,PREX2,DTNA,ABLIM1,PON2,MAML2,NKAIN3,PCDH9,FGFR3,CST3,GLI3,ACSS1,COL5A3
2.467e-03	-6.00	response to alkaloid	biological process	GO:0043279	100	3	18204	49	SLC1A2,RYR3,SLC1A3
2.476e-03	-6.00	parathyroid	COSMIC cancer mutations	parathyroid	476	6	16828	49	GPC5,PAMR1,TRPS1,MACF1,RYR3,GPM6A
2.564e-03	-5.97	perinuclear endoplasmic reticulum lumen	cellular component	GO:0099020	1	1	19108	49	CLU
2.566e-03	-5.97	positive regulation of oligodendrocyte differentiation	biological process	GO:0048714	28	2	18204	49	PTPRZ1,QKI
2.566e-03	-5.97	glial cell proliferation	biological process	GO:0014009	28	2	18204	49	NFIA,CLU
2.570e-03	-5.96	ZNF75D (zinc finger protein 75D)	protein interactions	7626	1	1	19454	50	ARHGAP24
2.570e-03	-5.96	ZNF880 (zinc finger protein 880)	protein interactions	400713	1	1	19454	50	ARHGAP24
2.570e-03	-5.96	ZNF780B (zinc finger protein 780B)	protein interactions	163131	1	1	19454	50	ARHGAP24
2.570e-03	-5.96	Isl1 (ISL1 transcription factor, LIM/homeodomain)	protein interactions	16392	1	1	19454	50	GLIS3
2.570e-03	-5.96	Hipk3 (homeodomain interacting protein kinase 3)	protein interactions	15259	1	1	19454	50	GLIS3
2.570e-03	-5.96	Sh2b1 (SH2B adaptor protein 1)	protein interactions	20399	1	1	19454	50	FGFR3
2.570e-03	-5.96	1700006A11Rik (RIKEN cDNA 1700006A11 gene)	protein interactions	71824	1	1	19454	50	BMPR1B
2.570e-03	-5.96	Lztr1 (leucine-zipper-like transcriptional regulator, 1)	protein interactions	66863	1	1	19454	50	BMPR1B
2.570e-03	-5.96	ZNF781 (zinc finger protein 781)	protein interactions	163115	1	1	19454	50	ARHGAP24
2.570e-03	-5.96	Agtrap (angiotensin II, type I receptor-associated protein)	protein interactions	11610	1	1	19454	50	PITPNC1
2.570e-03	-5.96	fgf3.L (fibroblast growth factor 3 L homeolog)	protein interactions	373669	1	1	19454	50	FGFR3
2.570e-03	-5.96	Dcaf7 (DDB1 and CUL4 associated factor 7)	protein interactions	71833	1	1	19454	50	BMPR1B
2.570e-03	-5.96	ZNF729 (zinc finger protein 729)	protein interactions	100287226	1	1	19454	50	ARHGAP24
2.653e-03	-5.93	internal N(7)-methylguanine-containing RNA reader activity	molecular function	GO:0160089	1	1	18094	48	QKI
2.653e-03	-5.93	metal chelating activity	molecular function	GO:0046911	1	1	18094	48	APOE
2.671e-03	-5.93	human chr20p11.21	chromosome location	human chr20p11.21	40	2	26134	50	CST3,ACSS1
2.673e-03	-5.92	amino acid:monoatomic cation symporter activity	molecular function	GO:0005416	29	2	18094	48	SLC1A2,SLC1A3
2.673e-03	-5.92	lipoprotein particle receptor binding	molecular function	GO:0070325	29	2	18094	48	CLU,APOE
2.681e-03	-5.92	marginal_zone_lymphoma	COSMIC cancer mutations	marginal_zone_lymphoma	331	5	16828	49	MEIS2,SORBS1,PARD3B,NTM,PTPRZ1
2.692e-03	-5.92	intermediate-density lipoprotein particle clearance	biological process	GO:0071831	1	1	18204	49	APOE
2.692e-03	-5.92	lateral semicircular canal development	biological process	GO:0060875	1	1	18204	49	GLI3
2.692e-03	-5.92	sagittal suture morphogenesis	biological process	GO:0060367	1	1	18204	49	GLI3
2.692e-03	-5.92	lambdoid suture morphogenesis	biological process	GO:0060366	1	1	18204	49	GLI3
2.692e-03	-5.92	positive regulation of transport across blood-brain barrier	biological process	GO:0150201	1	1	18204	49	APOE
2.692e-03	-5.92	regulation of lipid transport across blood-brain barrier	biological process	GO:1903000	1	1	18204	49	APOE
2.692e-03	-5.92	regulation of heparan sulfate proteoglycan binding	biological process	GO:1905858	1	1	18204	49	APOE
2.692e-03	-5.92	subpallium cell proliferation in forebrain	biological process	GO:0022012	1	1	18204	49	GLI3
2.692e-03	-5.92	lateral ganglionic eminence cell proliferation	biological process	GO:0022018	1	1	18204	49	GLI3
2.692e-03	-5.92	positive regulation of neurofibrillary tangle assembly	biological process	GO:1902998	1	1	18204	49	CLU
2.692e-03	-5.92	negative regulation of collagen catabolic process	biological process	GO:0010711	1	1	18204	49	CST3
2.692e-03	-5.92	anterior semicircular canal development	biological process	GO:0060873	1	1	18204	49	GLI3
2.692e-03	-5.92	regulation of neuronal signal transduction	biological process	GO:1902847	1	1	18204	49	CLU
2.692e-03	-5.92	negative regulation of elastin catabolic process	biological process	GO:0060311	1	1	18204	49	CST3
2.692e-03	-5.92	regulation of transport across blood-brain barrier	biological process	GO:0150200	1	1	18204	49	APOE
2.692e-03	-5.92	positive regulation of lipid transport across blood-brain barrier	biological process	GO:1903002	1	1	18204	49	APOE
2.692e-03	-5.92	regulation of cellular response to very-low-density lipoprotein particle stimulus	biological process	GO:1905890	1	1	18204	49	APOE
2.692e-03	-5.92	positive regulation of heparan sulfate proteoglycan binding	biological process	GO:1905860	1	1	18204	49	APOE
2.700e-03	-5.91	TRPS1	interpro domains	IPR028440	1	1	18521	50	TRPS1
2.700e-03	-5.91	SORBS1_SH3	interpro domains	IPR035606	1	1	18521	50	SORBS1
2.700e-03	-5.91	Clusterin_CS	interpro domains	IPR033986	1	1	18521	50	CLU
2.700e-03	-5.91	STAR_dimer	interpro domains	IPR032377	1	1	18521	50	QKI
2.700e-03	-5.91	Quaking_NLS	interpro domains	IPR032367	1	1	18521	50	QKI
2.700e-03	-5.91	SPARC-like_p1	interpro domains	IPR016359	1	1	18521	50	SPARCL1
2.700e-03	-5.91	SORBS1_SH3_2	interpro domains	IPR035611	1	1	18521	50	SORBS1
2.700e-03	-5.91	Rex2_DEP_1	interpro domains	IPR037367	1	1	18521	50	PREX2
2.700e-03	-5.91	Clusterin	interpro domains	IPR016016	1	1	18521	50	CLU
2.700e-03	-5.91	SORBS1_SH3_1	interpro domains	IPR035610	1	1	18521	50	SORBS1
2.700e-03	-5.91	M14_CPE_CPD	interpro domains	IPR034232	1	1	18521	50	CPE
2.700e-03	-5.91	MAML2_TAD	interpro domains	IPR048452	1	1	18521	50	MAML2
2.709e-03	-5.91	large_intestine-caecum-carcinoma-adenocarcinoma	COSMIC cancer mutations	large_intestine-caecum-carcinoma-adenocarcinoma	14236	48	16828	49	PCDH9,NKAIN3,AMZ2,GLI3,FGFR3,DTNA,PON2,APOE,PREX2,PARD3B,CDH20,ARHGAP24,GLIS3,SPON1,SLC1A3,NDRG2,PTPRZ1,MACF1,PITPNC1,CTNND2,GPC5,QKI,ATP13A4,SLC4A4,MEIS2,NPAS3,NTM,COL5A3,FBXL7,ACSS1,CST3,ABLIM1,CLU,MAML2,GPM6A,SORBS1,NFIA,TRPS1,PTGDS,NHSL1,PAMR1,BMPR1B,RYR3,SLC1A2,LSAMP,SPARCL1,AQP4,CPE
2.809e-03	-5.87	caecum	COSMIC cancer mutations	caecum	14248	48	16828	49	GLIS3,SLC1A3,SPON1,PTPRZ1,NDRG2,MACF1,PITPNC1,CTNND2,GPC5,SLC4A4,QKI,ATP13A4,NPAS3,MEIS2,NTM,AMZ2,NKAIN3,PCDH9,GLI3,FGFR3,DTNA,PON2,APOE,PREX2,PARD3B,CDH20,ARHGAP24,BMPR1B,SLC1A2,RYR3,LSAMP,SPARCL1,AQP4,CPE,ACSS1,FBXL7,COL5A3,CST3,CLU,ABLIM1,MAML2,SORBS1,GPM6A,TRPS1,NFIA,PTGDS,PAMR1,NHSL1
2.810e-03	-5.87	Peptidase_M54	pfam domains	PF07998	1	1	17795	50	AMZ2
2.810e-03	-5.87	FGFR3_TM	pfam domains	PF21165	1	1	17795	50	FGFR3
2.810e-03	-5.87	STAR_dimer	pfam domains	PF16544	1	1	17795	50	QKI
2.810e-03	-5.87	Quaking_NLS	pfam domains	PF16551	1	1	17795	50	QKI
2.810e-03	-5.87	MAML2_TAD	pfam domains	PF20804	1	1	17795	50	MAML2
2.857e-03	-5.86	cell body	cellular component	GO:0044297	556	6	19108	49	BMPR1B,CTNND2,SLC1A2,SLC1A3,GPM6A,APOE
2.857e-03	-5.86	catenin complex	cellular component	GO:0016342	31	2	19108	49	CTNNA2,CDH20
2.862e-03	-5.86	ACTB (actin beta)	protein interactions	60	958	8	19454	50	ABLIM1,ARHGAP24,MACF1,APOE,DTNA,NHSL1,MEIS2,SORBS1
2.917e-03	-5.84	t(4;14) translocations of FGFR3	REACTOME pathways	R-HSA-2033515	1	1	10285	30	FGFR3
2.942e-03	-5.83	L-glutamate import	biological process	GO:0051938	30	2	18204	49	SLC1A2,SLC1A3
2.942e-03	-5.83	neurotransmitter uptake	biological process	GO:0001504	30	2	18204	49	SLC1A3,SLC1A2
3.041e-03	-5.80	-	gene3d domains	6.10.250.1740	1	1	14470	44	FGFR3
3.041e-03	-5.80	-	gene3d domains	1.20.5.4010	1	1	14470	44	QKI
3.055e-03	-5.79	CDH1 (cadherin 1)	protein interactions	999	757	7	19454	50	NDRG2,CTNND2,CTNNA2,ABLIM1,MACF1,NHSL1,SORBS1
3.072e-03	-5.79	upper_aerodigestive_tract-pharynx-carcinoma-squamous_cell_carcinoma	COSMIC cancer mutations	upper_aerodigestive_tract-pharynx-carcinoma-squamous_cell_carcinoma	1485	11	16828	49	SORBS1,RYR3,PREX2,PCDH9,GPC5,PTPRZ1,FGFR3,PARD3B,DTNA,MACF1,NPAS3
3.219e-03	-5.74	skin-leg-malignant_melanoma-superficial_spreading	COSMIC cancer mutations	skin-leg-malignant_melanoma-superficial_spreading	210	4	16828	49	SLC4A4,ATP13A4,COL5A3,NTM
3.224e-03	-5.74	human chr11p13	chromosome location	human chr11p13	44	2	26134	50	SLC1A2,PAMR1
3.249e-03	-5.73	VLDLR (very low density lipoprotein receptor)	protein interactions	7436	33	2	19454	50	CLU,APOE
3.249e-03	-5.73	KATNAL1 (katanin catalytic subunit A1 like 1)	protein interactions	84056	33	2	19454	50	PITPNC1,ARHGAP24
3.253e-03	-5.73	intestinal_adenocarcinoma	COSMIC cancer mutations	intestinal_adenocarcinoma	7225	31	16828	49	PITPNC1,MACF1,SPON1,PTPRZ1,NTM,AQP4,ATP13A4,QKI,SLC4A4,MEIS2,NPAS3,RYR3,CTNND2,SLC1A2,LSAMP,CLU,MAML2,PCDH9,FGFR3,CST3,GLI3,COL5A3,FBXL7,ACSS1,NHSL1,CDH20,ARHGAP24,NFIA,TRPS1,PARD3B,PREX2
3.253e-03	-5.73	stomach-carcinoma-intestinal_adenocarcinoma	COSMIC cancer mutations	stomach-carcinoma-intestinal_adenocarcinoma	7225	31	16828	49	COL5A3,FBXL7,ACSS1,PCDH9,GLI3,CST3,FGFR3,CLU,MAML2,PREX2,NFIA,TRPS1,PARD3B,NHSL1,CDH20,ARHGAP24,SPON1,PTPRZ1,MACF1,PITPNC1,RYR3,CTNND2,SLC1A2,LSAMP,AQP4,QKI,ATP13A4,SLC4A4,NPAS3,MEIS2,NTM
3.261e-03	-5.73	plasma membrane bounded cell projection organization	biological process	GO:0120036	1152	9	18204	49	PREX2,BMPR1B,PTPRZ1,GLI3,CTNNA2,ABLIM1,CTNND2,GPM6A,APOE
3.344e-03	-5.70	positive regulation of cartilage development	biological process	GO:0061036	32	2	18204	49	GLI3,BMPR1B
3.344e-03	-5.70	transepithelial transport	biological process	GO:0070633	32	2	18204	49	SLC1A3,SLC1A2
3.353e-03	-5.70	HNRNPL (heterogeneous nuclear ribonucleoprotein L)	protein interactions	3191	1958	12	19454	50	NFIA,FGFR3,QKI,TRPS1,ABLIM1,BMPR1B,PON2,DTNA,ARHGAP24,MACF1,MSI2,PARD3B
3.430e-03	-5.68	skin-malignant_melanoma-acral_lentiginous	COSMIC cancer mutations	skin-malignant_melanoma-acral_lentiginous	30	2	16828	49	PREX2,FGFR3
3.430e-03	-5.68	lentigo_maligna	COSMIC cancer mutations	lentigo_maligna	30	2	16828	49	PREX2,FGFR3
3.447e-03	-5.67	CLUSTERIN_2	prosite domains	PS00493	1	1	12186	42	CLU
3.447e-03	-5.67	CLUSTERIN_1	prosite domains	PS00492	1	1	12186	42	CLU
3.465e-03	-5.67	CEACAM8 (CEA cell adhesion molecule 8)	protein interactions	1088	118	3	19454	50	CPE,APOE,CLU
3.476e-03	-5.66	connective tissue development	biological process	GO:0061448	232	4	18204	49	GLI3,FGFR3,NFIA,BMPR1B
3.482e-03	-5.66	cell adhesion molecule binding	molecular function	GO:0050839	560	6	18094	48	CDH20,CPE,CTNNA2,PTPRZ1,CTNND2,MACF1
3.486e-03	-5.66	dendrite development	biological process	GO:0016358	113	3	18204	49	CTNNA2,CTNND2,PREX2
3.504e-03	-5.65	eye development	biological process	GO:0001654	381	5	18204	49	GPM6A,BMPR1B,MEIS2,NFIA,GLI3
3.548e-03	-5.64	HLA-DPA1 (major histocompatibility complex, class II, DP alpha 1)	protein interactions	3113	119	3	19454	50	CLU,PCDH9,APOE
3.602e-03	-5.63	DELLA	smart domains	SM01129	1	1	9717	35	MACF1
3.615e-03	-5.62	trunk	COSMIC cancer mutations	trunk	3554	19	16828	49	ABLIM1,MAML2,MACF1,SLC1A3,PCDH9,PTPRZ1,FGFR3,GLIS3,CDH20,ATP13A4,CPE,MEIS2,NPAS3,SPARCL1,TRPS1,CTNND2,RYR3,PREX2,LSAMP
3.624e-03	-5.62	Transport of inorganic cations/anions and amino acids/oligopeptides	REACTOME pathways	R-HSA-425393	107	3	10285	30	SLC4A4,SLC1A3,SLC1A2
3.663e-03	-5.61	fatty acid biosynthetic process	biological process	GO:0006633	115	3	18204	49	PTGDS,ACSS1,QKI
3.663e-03	-5.61	visual system development	biological process	GO:0150063	385	5	18204	49	NFIA,GLI3,MEIS2,BMPR1B,GPM6A
3.680e-03	-5.60	synapse	cellular component	GO:0045202	1473	10	19108	49	GPM6A,APOE,SPARCL1,SLC1A3,PTPRZ1,CLU,DTNA,CTNND2,QKI,SLC1A2
3.688e-03	-5.60	solute:monoatomic cation symporter activity	molecular function	GO:0015294	117	3	18094	48	SLC4A4,SLC1A2,SLC1A3
3.826e-03	-5.57	AQUAPORIN4	prints domains	PR02016	1	1	5227	20	AQP4
3.839e-03	-5.56	lipoprotein particle	cellular component	GO:1990777	36	2	19108	49	CLU,APOE
3.839e-03	-5.56	plasma lipoprotein particle	cellular component	GO:0034358	36	2	19108	49	APOE,CLU
3.878e-03	-5.55	organic acid:sodium symporter activity	molecular function	GO:0005343	35	2	18094	48	SLC1A3,SLC1A2
3.912e-03	-5.54	sensory system development	biological process	GO:0048880	391	5	18204	49	MEIS2,BMPR1B,GPM6A,NFIA,GLI3
3.978e-03	-5.53	eye-uveal_tract-malignant_melanoma-spindle	COSMIC cancer mutations	eye-uveal_tract-malignant_melanoma-spindle	363	5	16828	49	CPE,CTNND2,PREX2,MACF1,PCDH9
3.990e-03	-5.52	neuron fate specification	biological process	GO:0048665	35	2	18204	49	GLI3,NFIA
4.052e-03	-5.51	glial cell projection	cellular component	GO:0097386	37	2	19108	49	SLC1A2,AQP4
4.071e-03	-5.50	HPCA (hippocalcin)	protein interactions	3208	37	2	19454	50	CST3,GPM6A
4.094e-03	-5.50	transporter activity	molecular function	GO:0005215	1211	9	18094	48	GPM6A,SLC1A2,SLC4A4,ATP13A4,AQP4,PITPNC1,APOE,SLC1A3,RYR3
4.099e-03	-5.50	proteoglycan binding	molecular function	GO:0043394	36	2	18094	48	COL5A3,APOE
4.258e-03	-5.46	EPB41L4A (erythrocyte membrane protein band 4.1 like 4A)	protein interactions	64097	127	3	19454	50	ABLIM1,MACF1,DTNA
4.275e-03	-5.45	cell projection organization	biological process	GO:0030030	1200	9	18204	49	BMPR1B,PREX2,ABLIM1,CTNNA2,CTNND2,GPM6A,APOE,PTPRZ1,GLI3
4.281e-03	-5.45	positive regulation of neurogenesis	biological process	GO:0050769	246	4	18204	49	QKI,PTPRZ1,GLI3,MACF1
4.290e-03	-5.45	MMP3 (matrix metallopeptidase 3)	protein interactions	4314	38	2	19454	50	APOE,CLU
4.290e-03	-5.45	Pcbp1 (poly(rC) binding protein 1)	protein interactions	23983	38	2	19454	50	QKI,MSI2
4.391e-03	-5.43	central_nervous_system-parietal_lobe-glioma-astrocytoma_Grade_I	COSMIC cancer mutations	central_nervous_system-parietal_lobe-glioma-astrocytoma_Grade_I	34	2	16828	49	QKI,FGFR3
4.448e-03	-5.42	central_nervous_system-brainstem-glioma-oligoastrocytoma_Grade_III	COSMIC cancer mutations	central_nervous_system-brainstem-glioma-oligoastrocytoma_Grade_III	114	3	16828	49	PREX2,SLC1A2,RYR3
4.451e-03	-5.41	positive regulation of glucose import	biological process	GO:0046326	37	2	18204	49	SLC1A2,SORBS1
4.491e-03	-5.41	intracellular chemical homeostasis	biological process	GO:0055082	581	6	18204	49	SLC4A4,AQP4,ATP13A4,APOE,RYR3,SLC1A3
4.493e-03	-5.41	protein-lipid complex	cellular component	GO:0032994	39	2	19108	49	CLU,APOE
4.496e-03	-5.40	skin-face-carcinoma-squamous_cell_carcinoma	COSMIC cancer mutations	skin-face-carcinoma-squamous_cell_carcinoma	2036	13	16828	49	PTPRZ1,FGFR3,PCDH9,MACF1,ABLIM1,TRPS1,GPC5,LSAMP,PREX2,GPM6A,ARHGAP24,MSI2,AQP4
4.691e-03	-5.36	amino acid import across plasma membrane	biological process	GO:0089718	38	2	18204	49	SLC1A3,SLC1A2
4.783e-03	-5.34	lung-carcinoma-small_cell_carcinoma	COSMIC cancer mutations	lung-carcinoma-small_cell_carcinoma	9908	38	16828	49	ARHGAP24,PAMR1,CDH20,MSI2,PARD3B,NFIA,TRPS1,PREX2,GPM6A,SORBS1,MAML2,ABLIM1,CLU,DTNA,GLI3,FGFR3,CST3,PCDH9,NKAIN3,COL5A3,FBXL7,NTM,NPAS3,MEIS2,CPE,ATP13A4,QKI,SLC4A4,GPC5,SPARCL1,RYR3,CTNND2,PITPNC1,MACF1,PTPRZ1,NDRG2,SPON1,BMPR1B
4.840e-03	-5.33	small_cell_carcinoma	COSMIC cancer mutations	small_cell_carcinoma	9913	38	16828	49	CDH20,PAMR1,MSI2,ARHGAP24,TRPS1,NFIA,PARD3B,SORBS1,GPM6A,PREX2,DTNA,CLU,ABLIM1,MAML2,NKAIN3,PCDH9,FGFR3,GLI3,CST3,FBXL7,COL5A3,NTM,SLC4A4,QKI,CPE,ATP13A4,MEIS2,NPAS3,SPARCL1,GPC5,CTNND2,RYR3,PITPNC1,MACF1,SPON1,NDRG2,PTPRZ1,BMPR1B
4.912e-03	-5.32	central_nervous_system-thalamus-glioma-astrocytoma_Grade_I	COSMIC cancer mutations	central_nervous_system-thalamus-glioma-astrocytoma_Grade_I	36	2	16828	49	FGFR3,QKI
4.918e-03	-5.31	cell differentiation	biological process	GO:0030154	3645	18	18204	49	GLI3,GPM6A,NHSL1,CTNNA2,PREX2,NFIA,QKI,FGFR3,NDRG2,BMPR1B,NTM,PTPRZ1,APOE,CTNND2,SLC1A3,ARHGAP24,MSI2,CLU
4.936e-03	-5.31	positive regulation of nitric oxide biosynthetic process	biological process	GO:0045429	39	2	18204	49	CLU,APOE
4.945e-03	-5.31	NUFIP1 (nuclear FMR1 interacting protein 1)	protein interactions	26747	134	3	19454	50	NTM,GPM6A,CPE
4.963e-03	-5.31	cellular developmental process	biological process	GO:0048869	3648	18	18204	49	MSI2,ARHGAP24,CLU,PTPRZ1,APOE,CTNND2,SLC1A3,PREX2,QKI,NFIA,FGFR3,NDRG2,BMPR1B,NTM,GLI3,GPM6A,NHSL1,CTNNA2
5.090e-03	-5.28	cation binding	molecular function	GO:0043169	4341	20	18094	48	SLC1A3,APOE,ATP13A4,SPARCL1,TRPS1,DTNA,PON2,RYR3,PAMR1,BMPR1B,GLI3,MACF1,CPE,ACSS1,PCDH9,SPON1,ABLIM1,SLC1A2,AMZ2,GLIS3
5.122e-03	-5.27	discoidal high-density lipoprotein particle	cellular component	GO:0034365	2	1	19108	49	APOE
5.122e-03	-5.27	chylomicron remnant	cellular component	GO:0034360	2	1	19108	49	APOE
5.123e-03	-5.27	cell development	biological process	GO:0048468	2236	13	18204	49	MSI2,CLU,PTPRZ1,APOE,CTNND2,SLC1A3,PREX2,QKI,BMPR1B,NTM,GLI3,GPM6A,CTNNA2
5.127e-03	-5.27	EF-hand-dom_pair	interpro domains	IPR011992	258	4	18521	50	RYR3,MACF1,SPARCL1,DTNA
5.134e-03	-5.27	Irf7 (interferon regulatory factor 7)	protein interactions	54123	2	1	19454	50	BMPR1B
5.134e-03	-5.27	Klhl1 (kelch-like 1)	protein interactions	93688	2	1	19454	50	BMPR1B
5.134e-03	-5.27	Ppp3cc (protein phosphatase 3, catalytic subunit, gamma isoform)	protein interactions	19057	2	1	19454	50	BMPR1B
5.134e-03	-5.27	Fkbp1b (FK506 binding protein 1b)	protein interactions	14226	2	1	19454	50	BMPR1B
5.134e-03	-5.27	ZNF680 (zinc finger protein 680)	protein interactions	340252	2	1	19454	50	ARHGAP24
5.134e-03	-5.27	Bmpr2 (bone morphogenetic protein receptor type 2)	protein interactions	12168	2	1	19454	50	BMPR1B
5.134e-03	-5.27	Fkbp1a (FK506 binding protein 1a)	protein interactions	14225	2	1	19454	50	BMPR1B
5.134e-03	-5.27	Kdm4c (lysine (K)-specific demethylase 4C)	protein interactions	76804	2	1	19454	50	GLIS3
5.134e-03	-5.27	Bcr (BCR activator of RhoGEF and GTPase)	protein interactions	110279	2	1	19454	50	BMPR1B
5.134e-03	-5.27	Mknk2 (MAP kinase-interacting serine/threonine kinase 2)	protein interactions	17347	2	1	19454	50	BMPR1B
5.134e-03	-5.27	Sh3kbp1 (SH3-domain kinase binding protein 1)	protein interactions	58194	2	1	19454	50	BMPR1B
5.134e-03	-5.27	Fbxo34 (F-box protein 34)	protein interactions	78938	2	1	19454	50	BMPR1B
5.134e-03	-5.27	ZNF658B (zinc finger protein 658B (pseudogene))	protein interactions	401509	2	1	19454	50	ARHGAP24
5.134e-03	-5.27	Zmym2 (zinc finger, MYM-type 2)	protein interactions	76007	2	1	19454	50	GLIS3
5.184e-03	-5.26	central_nervous_system-third_ventricle-glioma-astrocytoma_Grade_I	COSMIC cancer mutations	central_nervous_system-third_ventricle-glioma-astrocytoma_Grade_I	37	2	16828	49	QKI,FGFR3
5.187e-03	-5.26	positive regulation of nitric oxide metabolic process	biological process	GO:1904407	40	2	18204	49	APOE,CLU
5.198e-03	-5.26	RDX (radixin)	protein interactions	5962	272	4	19454	50	FGFR3,MACF1,ABLIM1,ARHGAP24
5.251e-03	-5.25	oligoastrocytoma_Grade_II	COSMIC cancer mutations	oligoastrocytoma_Grade_II	121	3	16828	49	FGFR3,CDH20,DTNA
5.376e-03	-5.23	larynx development	biological process	GO:0120224	2	1	18204	49	GLI3
5.376e-03	-5.23	regulation of neurofibrillary tangle assembly	biological process	GO:1902996	2	1	18204	49	CLU
5.376e-03	-5.23	larynx morphogenesis	biological process	GO:0120223	2	1	18204	49	GLI3
5.376e-03	-5.23	propionate biosynthetic process	biological process	GO:0019542	2	1	18204	49	ACSS1
5.376e-03	-5.23	fibroblast growth factor receptor apoptotic signaling pathway	biological process	GO:1902178	2	1	18204	49	FGFR3
5.376e-03	-5.23	acetyl-CoA biosynthetic process from acetate	biological process	GO:0019427	2	1	18204	49	ACSS1
5.376e-03	-5.23	regulation of elastin catabolic process	biological process	GO:0060310	2	1	18204	49	CST3
5.376e-03	-5.23	lipid transport involved in lipid storage	biological process	GO:0010877	2	1	18204	49	APOE
5.376e-03	-5.23	negative regulation of blood vessel remodeling	biological process	GO:0060313	2	1	18204	49	CST3
5.376e-03	-5.23	negative regulation of 3'-UTR-mediated mRNA stabilization	biological process	GO:1905869	2	1	18204	49	QKI
5.376e-03	-5.23	mammary gland specification	biological process	GO:0060594	2	1	18204	49	GLI3
5.376e-03	-5.23	myofibroblast contraction	biological process	GO:1990764	2	1	18204	49	QKI
5.376e-03	-5.23	smoothened signaling pathway involved in spinal cord motor neuron cell fate specification	biological process	GO:0021776	2	1	18204	49	GLI3
5.376e-03	-5.23	acetate biosynthetic process	biological process	GO:0019413	2	1	18204	49	ACSS1
5.392e-03	-5.22	Pept_M54_archaemetzincn	interpro domains	IPR012962	2	1	18521	50	AMZ2
5.392e-03	-5.22	MSI_RRM2	interpro domains	IPR034126	2	1	18521	50	MSI2
5.392e-03	-5.22	Osteonectin_CS	interpro domains	IPR001999	2	1	18521	50	SPARCL1
5.392e-03	-5.22	Distrobrevin	interpro domains	IPR017432	2	1	18521	50	DTNA
5.392e-03	-5.22	Clusterin_N	interpro domains	IPR016014	2	1	18521	50	CLU
5.392e-03	-5.22	Spondin_N_sf	interpro domains	IPR038678	2	1	18521	50	SPON1
5.392e-03	-5.22	Clusterin_C	interpro domains	IPR016015	2	1	18521	50	CLU
5.392e-03	-5.22	Alpha_CARP_receptor-type	interpro domains	IPR041887	2	1	18521	50	PTPRZ1
5.392e-03	-5.22	Paraoxonase2	interpro domains	IPR008364	2	1	18521	50	PON2
5.392e-03	-5.22	Ac_CoA_lig	interpro domains	IPR011904	2	1	18521	50	ACSS1
5.392e-03	-5.22	Clusterin-like	interpro domains	IPR000753	2	1	18521	50	CLU
5.392e-03	-5.22	Par3/HAL_N	interpro domains	IPR021922	2	1	18521	50	PARD3B
5.392e-03	-5.22	Spondin_N	interpro domains	IPR009465	2	1	18521	50	SPON1
5.432e-03	-5.22	Ig_I-set	interpro domains	IPR013098	132	3	18521	50	FGFR3,NTM,LSAMP
5.461e-03	-5.21	central_nervous_system-brainstem-glioma-astrocytoma_Grade_I	COSMIC cancer mutations	central_nervous_system-brainstem-glioma-astrocytoma_Grade_I	38	2	16828	49	QKI,FGFR3
5.545e-03	-5.19	neutral L-amino acid transmembrane transporter activity	molecular function	GO:0015175	42	2	18094	48	SLC1A2,SLC1A3
5.565e-03	-5.19	regulation of canonical Wnt signaling pathway	biological process	GO:0060828	265	4	18204	49	CTNND2,APOE,GPC5,GLI3
5.612e-03	-5.18	Spond_N	pfam domains	PF06468	2	1	17795	50	SPON1
5.612e-03	-5.18	Clusterin	pfam domains	PF01093	2	1	17795	50	CLU
5.612e-03	-5.18	Reeler	pfam domains	PF02014	2	1	17795	50	SPON1
5.612e-03	-5.18	Par3_HAL_N_term	pfam domains	PF12053	2	1	17795	50	PARD3B
5.696e-03	-5.17	UPK2 (uroplakin 2)	protein interactions	7379	141	3	19454	50	CTNNA2,PON2,PCDH9
5.721e-03	-5.16	intracellular monoatomic cation homeostasis	biological process	GO:0030003	428	5	18204	49	SLC1A3,APOE,RYR3,SLC4A4,ATP13A4
5.767e-03	-5.16	sarcolemma	cellular component	GO:0042383	142	3	19108	49	AQP4,RYR3,DTNA
5.802e-03	-5.15	mast_cell_neoplasm	COSMIC cancer mutations	mast_cell_neoplasm	248	4	16828	49	NPAS3,PCDH9,NFIA,GPC5
5.802e-03	-5.15	haematopoietic_and_lymphoid_tissue-haematopoietic_neoplasm-mast_cell_neoplasm	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue-haematopoietic_neoplasm-mast_cell_neoplasm	248	4	16828	49	NFIA,GPC5,PCDH9,NPAS3
5.806e-03	-5.15	tau protein binding	molecular function	GO:0048156	43	2	18094	48	CLU,APOE
5.885e-03	-5.14	central_nervous_system-brain-glioma-oligodendroglioma_Grade_III	COSMIC cancer mutations	central_nervous_system-brain-glioma-oligodendroglioma_Grade_III	249	4	16828	49	MACF1,GLIS3,FGFR3,PTPRZ1
5.890e-03	-5.13	response to wounding	biological process	GO:0009611	431	5	18204	49	NFIA,ARHGAP24,SLC1A3,MACF1,SLC1A2
5.935e-03	-5.13	active monoatomic ion transmembrane transporter activity	molecular function	GO:0022853	274	4	18094	48	SLC4A4,ATP13A4,SLC1A2,SLC1A3
6.018e-03	-5.11	carboxylic acid biosynthetic process	biological process	GO:0046394	271	4	18204	49	PTGDS,SLC1A3,ACSS1,QKI
6.064e-03	-5.11	I-set	pfam domains	PF07679	132	3	17795	50	FGFR3,LSAMP,NTM
6.073e-03	-5.10	F-spondin domain	gene3d domains	2.60.40.2130	2	1	14470	44	SPON1
6.073e-03	-5.10	Vinculin, Vh2 four-helix bundle	gene3d domains	1.20.120.810	2	1	14470	44	CTNNA2
6.073e-03	-5.10	-	gene3d domains	6.20.350.10	2	1	14470	44	RYR3
6.098e-03	-5.10	scalp	COSMIC cancer mutations	scalp	2110	13	16828	49	PTPRZ1,FGFR3,COL5A3,MACF1,TRPS1,NFIA,GPC5,SORBS1,LSAMP,PREX2,NTM,SLC4A4,ATP13A4
6.107e-03	-5.10	axon	cellular component	GO:0030424	650	6	19108	49	GPM6A,PCDH9,DTNA,NDRG2,SLC1A2,CTNNA2
6.141e-03	-5.09	metal ion transmembrane transporter activity	molecular function	GO:0046873	442	5	18094	48	SLC4A4,GPM6A,SLC1A2,SLC1A3,RYR3
6.159e-03	-5.09	monoatomic cation transmembrane transporter activity	molecular function	GO:0008324	630	6	18094	48	RYR3,SLC1A3,SLC1A2,ATP13A4,GPM6A,SLC4A4
6.174e-03	-5.09	vascular process in circulatory system	biological process	GO:0003018	273	4	18204	49	SLC1A3,APOE,SLC1A2,SLC4A4
6.238e-03	-5.08	intracellular monoatomic ion homeostasis	biological process	GO:0006873	437	5	18204	49	APOE,RYR3,SLC1A3,SLC4A4,ATP13A4
6.247e-03	-5.08	positive regulation of glucose transmembrane transport	biological process	GO:0010828	44	2	18204	49	SORBS1,SLC1A2
6.254e-03	-5.07	organic acid biosynthetic process	biological process	GO:0016053	274	4	18204	49	ACSS1,QKI,PTGDS,SLC1A3
6.272e-03	-5.07	DSCR9 (Down syndrome critical region 9)	protein interactions	257203	146	3	19454	50	SPARCL1,CLU,MACF1
6.493e-03	-5.04	spleen	COSMIC cancer mutations	spleen	408	5	16828	49	PARD3B,NTM,PTPRZ1,MEIS2,SORBS1
6.500e-03	-5.04	CNTN1 (contactin 1)	protein interactions	1272	47	2	19454	50	PTPRZ1,GPM6A
6.527e-03	-5.03	acidic amino acid transport	biological process	GO:0015800	45	2	18204	49	SLC1A2,SLC1A3
6.588e-03	-5.02	monoatomic anion transmembrane transport	biological process	GO:0098656	142	3	18204	49	SLC1A2,SLC1A3,SLC4A4
6.588e-03	-5.02	positive regulation of small molecule metabolic process	biological process	GO:0062013	142	3	18204	49	APOE,SORBS1,SLC4A4
6.760e-03	-5.00	pseudomyxoma_peritonei	COSMIC cancer mutations	pseudomyxoma_peritonei	585	6	16828	49	FGFR3,TRPS1,MEIS2,COL5A3,MACF1,FBXL7
6.760e-03	-5.00	peritoneum-appendix-other-pseudomyxoma_peritonei	COSMIC cancer mutations	peritoneum-appendix-other-pseudomyxoma_peritonei	585	6	16828	49	MEIS2,MACF1,TRPS1,FGFR3,FBXL7,COL5A3
6.812e-03	-4.99	positive regulation of glial cell differentiation	biological process	GO:0045687	46	2	18204	49	QKI,PTPRZ1
6.812e-03	-4.99	regulation of oligodendrocyte differentiation	biological process	GO:0048713	46	2	18204	49	PTPRZ1,QKI
6.815e-03	-4.99	appendix	COSMIC cancer mutations	appendix	586	6	16828	49	FBXL7,MACF1,MEIS2,COL5A3,FGFR3,TRPS1
6.841e-03	-4.98	face	COSMIC cancer mutations	face	2139	13	16828	49	ABLIM1,AQP4,MACF1,MSI2,ARHGAP24,GPM6A,LSAMP,PREX2,TRPS1,PCDH9,GPC5,PTPRZ1,FGFR3
6.870e-03	-4.98	uveal_tract	COSMIC cancer mutations	uveal_tract	587	6	16828	49	FGFR3,PCDH9,PREX2,MACF1,CTNND2,CPE
6.870e-03	-4.98	peritoneum	COSMIC cancer mutations	peritoneum	587	6	16828	49	TRPS1,FGFR3,FBXL7,COL5A3,MACF1,MEIS2
6.882e-03	-4.98	OSTEONECTIN_2	prosite domains	PS00613	2	1	12186	42	SPARCL1
6.882e-03	-4.98	SPONDIN	prosite domains	PS51020	2	1	12186	42	SPON1
6.882e-03	-4.98	OSTEONECTIN_1	prosite domains	PS00612	2	1	12186	42	SPARCL1
6.997e-03	-4.96	Wnt signaling pathway	biological process	GO:0016055	283	4	18204	49	CPE,NDRG2,MACF1,CTNND2
7.049e-03	-4.95	HBZ (hemoglobin subunit zeta)	protein interactions	3050	49	2	19454	50	ARHGAP24,FGFR3
7.087e-03	-4.95	symporter activity	molecular function	GO:0015293	148	3	18094	48	SLC4A4,SLC1A3,SLC1A2
7.119e-03	-4.94	oligoastrocytoma_Grade_III	COSMIC cancer mutations	oligoastrocytoma_Grade_III	263	4	16828	49	FGFR3,PREX2,RYR3,SLC1A2
7.191e-03	-4.93	CLa	smart domains	SM00035	2	1	9717	35	CLU
7.191e-03	-4.93	CLb	smart domains	SM00030	2	1	9717	35	CLU
7.211e-03	-4.93	Retinoid metabolism and transport	REACTOME pathways	R-HSA-975634	44	2	10285	30	APOE,GPC5
7.263e-03	-4.92	NMT1 (N-myristoyltransferase 1)	protein interactions	4836	154	3	19454	50	ARHGAP24,ABLIM1,DTNA
7.266e-03	-4.92	soft_tissue-striated_muscle-rhabdomyosarcoma	COSMIC cancer mutations	soft_tissue-striated_muscle-rhabdomyosarcoma	594	6	16828	49	MACF1,TRPS1,SPON1,CTNND2,COL5A3,PREX2
7.272e-03	-4.92	Ig_3	pfam domains	PF13927	141	3	17795	50	NTM,LSAMP,FGFR3
7.306e-03	-4.92	Statin Pathway	WikiPathways	WP430	33	2	5310	21	ACSS1,APOE
7.404e-03	-4.91	large_intestine-adenoma	COSMIC cancer mutations	large_intestine-adenoma	266	4	16828	49	RYR3,GLI3,APOE,CDH20
7.493e-03	-4.89	cell surface	cellular component	GO:0009986	896	7	19108	49	CLU,SLC1A3,SLC1A2,GPC5,AQP4,SLC4A4,FGFR3
7.592e-03	-4.88	third_ventricle	COSMIC cancer mutations	third_ventricle	45	2	16828	49	FGFR3,QKI
7.617e-03	-4.88	Ndc80 (NDC80 kinetochore complex component)	protein interactions	67052	51	2	19454	50	MACF1,NHSL1
7.617e-03	-4.88	LINGO1 (leucine rich repeat and Ig domain containing 1)	protein interactions	84894	51	2	19454	50	NTM,PON2
7.631e-03	-4.88	human chr8q23.3	chromosome location	human chr8q23.3	4	1	26134	50	TRPS1
7.639e-03	-4.87	PARAOXONASE2	prints domains	PR01787	2	1	5227	20	PON2
7.691e-03	-4.87	Atg16l1 (autophagy related 16 like 1)	protein interactions	77040	3	1	19454	50	BMPR1B
7.691e-03	-4.87	Smad6 (SMAD family member 6)	protein interactions	17130	3	1	19454	50	BMPR1B
7.691e-03	-4.87	IL34 (interleukin 34)	protein interactions	146433	3	1	19454	50	PTPRZ1
7.691e-03	-4.87	ZNF257 (zinc finger protein 257)	protein interactions	113835	3	1	19454	50	ARHGAP24
7.691e-03	-4.87	QRFPR (pyroglutamylated RFamide peptide receptor)	protein interactions	84109	3	1	19454	50	NTM
7.691e-03	-4.87	ZNF506 (zinc finger protein 506)	protein interactions	440515	3	1	19454	50	ARHGAP24
7.691e-03	-4.87	Hk2 (hexokinase 2)	protein interactions	25059	3	1	19454	50	PTGDS
7.691e-03	-4.87	Lep (leptin)	protein interactions	16846	3	1	19454	50	CLU
7.691e-03	-4.87	BCO1 (beta-carotene oxygenase 1)	protein interactions	53630	3	1	19454	50	ABLIM1
7.691e-03	-4.87	Chn1 (chimerin 1)	protein interactions	108699	3	1	19454	50	BMPR1B
7.691e-03	-4.87	PIGL (phosphatidylinositol glycan anchor biosynthesis class L)	protein interactions	9487	3	1	19454	50	MEIS2
7.691e-03	-4.87	Shh (sonic hedgehog)	protein interactions	20423	3	1	19454	50	GLI3
7.691e-03	-4.87	Fbxw5 (F-box and WD-40 domain protein 5)	protein interactions	30839	3	1	19454	50	BMPR1B
7.691e-03	-4.87	ZNF540 (zinc finger protein 540)	protein interactions	163255	3	1	19454	50	ARHGAP24
7.691e-03	-4.87	ZNF682 (zinc finger protein 682)	protein interactions	91120	3	1	19454	50	ARHGAP24
7.691e-03	-4.87	Rap2a (RAS related protein 2a)	protein interactions	76108	3	1	19454	50	BMPR1B
7.691e-03	-4.87	ZNF716 (zinc finger protein 716)	protein interactions	441234	3	1	19454	50	ARHGAP24
7.691e-03	-4.87	Spop (speckle-type BTB/POZ protein)	protein interactions	20747	3	1	19454	50	GLIS3
7.691e-03	-4.87	Plekhb1 (pleckstrin homology domain containing, family B (evectins) member 1)	protein interactions	27276	3	1	19454	50	BMPR1B
7.691e-03	-4.87	Stk35 (serine/threonine kinase 35)	protein interactions	67333	3	1	19454	50	BMPR1B
7.691e-03	-4.87	Usp45 (ubiquitin specific petidase 45)	protein interactions	77593	3	1	19454	50	BMPR1B
7.700e-03	-4.87	astrocytoma_Grade_I	COSMIC cancer mutations	astrocytoma_Grade_I	139	3	16828	49	QKI,FGFR3,GPC5
7.750e-03	-4.86	diffuse_adenocarcinoma	COSMIC cancer mutations	diffuse_adenocarcinoma	4383	21	16828	49	PON2,MACF1,DTNA,CLU,ABLIM1,PTPRZ1,FGFR3,GLI3,SLC1A3,SPON1,PCDH9,ACSS1,GLIS3,NHSL1,MEIS2,QKI,TRPS1,PREX2,CTNND2,RYR3,GPM6A
7.750e-03	-4.86	stomach-carcinoma-diffuse_adenocarcinoma	COSMIC cancer mutations	stomach-carcinoma-diffuse_adenocarcinoma	4383	21	16828	49	RYR3,GPM6A,CTNND2,PREX2,TRPS1,QKI,MEIS2,NHSL1,ACSS1,GLIS3,PCDH9,SPON1,SLC1A3,FGFR3,GLI3,PTPRZ1,CLU,ABLIM1,DTNA,MACF1,PON2
7.761e-03	-4.86	C20 prostanoid biosynthesis	BIOCYC pathways	META_PWY66-374	7	1	902	1	PTGDS
7.761e-03	-4.86	C20 prostanoid biosynthesis	BIOCYC pathways	HUMAN_PWY66-374	7	1	902	1	PTGDS
7.928e-03	-4.84	TYRO3 (TYRO3 protein tyrosine kinase)	protein interactions	7301	159	3	19454	50	SLC1A3,CLU,APOE
7.938e-03	-4.84	lactonohydrolase activity	molecular function	GO:0046573	3	1	18094	48	PON2
7.938e-03	-4.84	acyl-L-homoserine-lactone lactonohydrolase activity	molecular function	GO:0102007	3	1	18094	48	PON2
7.938e-03	-4.84	cysteine transmembrane transporter activity	molecular function	GO:0033229	3	1	18094	48	SLC1A2
7.938e-03	-4.84	prostaglandin-D synthase activity	molecular function	GO:0004667	3	1	18094	48	PTGDS
7.984e-03	-4.83	eye	COSMIC cancer mutations	eye	606	6	16828	49	PCDH9,FGFR3,CTNND2,PREX2,CPE,MACF1
8.029e-03	-4.82	stomach-adenocarcinoma	COSMIC cancer mutations	stomach-adenocarcinoma	4101	20	16828	49	SLC4A4,QKI,ATP13A4,MEIS2,CDH20,PAMR1,CTNND2,SLC1A2,PREX2,TRPS1,GPC5,PARD3B,ABLIM1,PON2,MACF1,ACSS1,COL5A3,PCDH9,GLI3,FGFR3
8.054e-03	-4.82	cysteine transport	biological process	GO:0042883	3	1	18204	49	SLC1A2
8.054e-03	-4.82	immune complex clearance	biological process	GO:0002434	3	1	18204	49	CLU
8.054e-03	-4.82	acetate metabolic process	biological process	GO:0006083	3	1	18204	49	ACSS1
8.054e-03	-4.82	regulation of platelet-derived growth factor production	biological process	GO:0090361	3	1	18204	49	NDRG2
8.054e-03	-4.82	smoothened signaling pathway involved in ventral spinal cord interneuron specification	biological process	GO:0021775	3	1	18204	49	GLI3
8.054e-03	-4.82	radial glia guided migration of Purkinje cell	biological process	GO:0021942	3	1	18204	49	CTNNA2
8.054e-03	-4.82	cysteine transmembrane transport	biological process	GO:1903712	3	1	18204	49	SLC1A2
8.054e-03	-4.82	positive regulation of low-density lipoprotein particle receptor catabolic process	biological process	GO:0032805	3	1	18204	49	APOE
8.054e-03	-4.82	smoothened signaling pathway involved in ventral spinal cord patterning	biological process	GO:0021910	3	1	18204	49	GLI3
8.054e-03	-4.82	protein targeting to lysosome involved in chaperone-mediated autophagy	biological process	GO:0061740	3	1	18204	49	CLU
8.054e-03	-4.82	very-low-density lipoprotein particle clearance	biological process	GO:0034447	3	1	18204	49	APOE
8.054e-03	-4.82	nose morphogenesis	biological process	GO:0043585	3	1	18204	49	GLI3
8.078e-03	-4.82	Arylesterase	interpro domains	IPR002640	3	1	18521	50	PON2
8.078e-03	-4.82	Mastermind-like_N	interpro domains	IPR019082	3	1	18521	50	MAML2
8.078e-03	-4.82	Ryanodine_rcpt	interpro domains	IPR003032	3	1	18521	50	RYR3
8.078e-03	-4.82	MAML1-3	interpro domains	IPR046369	3	1	18521	50	MAML2
8.078e-03	-4.82	SoHo_dom	interpro domains	IPR003127	3	1	18521	50	SORBS1
8.078e-03	-4.82	MAML_N_sf	interpro domains	IPR046370	3	1	18521	50	MAML2
8.078e-03	-4.82	SPRY3_RyR	interpro domains	IPR035762	3	1	18521	50	RYR3
8.078e-03	-4.82	Myelin_PLP_CS	interpro domains	IPR018237	3	1	18521	50	GPM6A
8.078e-03	-4.82	Ryanrecept_TM4-6	interpro domains	IPR009460	3	1	18521	50	RYR3
8.078e-03	-4.82	Vinculin_CS	interpro domains	IPR000633	3	1	18521	50	CTNNA2
8.078e-03	-4.82	Ryan_recept	interpro domains	IPR013333	3	1	18521	50	RYR3
8.078e-03	-4.82	Myelin_PLP	interpro domains	IPR001614	3	1	18521	50	GPM6A
8.078e-03	-4.82	SPRY2_RyR	interpro domains	IPR035764	3	1	18521	50	RYR3
8.078e-03	-4.82	RYDR_Jsol	interpro domains	IPR048581	3	1	18521	50	RYR3
8.078e-03	-4.82	SPRY1_RyR	interpro domains	IPR035761	3	1	18521	50	RYR3
8.078e-03	-4.82	Reeler_sf	interpro domains	IPR042307	3	1	18521	50	SPON1
8.078e-03	-4.82	Reeler_dom	interpro domains	IPR002861	3	1	18521	50	SPON1
8.124e-03	-4.81	neuronal cell body	cellular component	GO:0043025	489	5	19108	49	APOE,GPM6A,SLC1A3,CTNND2,BMPR1B
8.172e-03	-4.81	positive regulation of nervous system development	biological process	GO:0051962	296	4	18204	49	QKI,PTPRZ1,GLI3,MACF1
8.406e-03	-4.78	RYDR_Jsol	pfam domains	PF21119	3	1	17795	50	RYR3
8.406e-03	-4.78	SR_plectin_7	pfam domains	PF21097	3	1	17795	50	MACF1
8.406e-03	-4.78	RR_TM4-6	pfam domains	PF06459	3	1	17795	50	RYR3
8.406e-03	-4.78	Myelin_PLP	pfam domains	PF01275	3	1	17795	50	GPM6A
8.406e-03	-4.78	MamL-1	pfam domains	PF09596	3	1	17795	50	MAML2
8.406e-03	-4.78	Arylesterase	pfam domains	PF01731	3	1	17795	50	PON2
8.406e-03	-4.78	RyR	pfam domains	PF02026	3	1	17795	50	RYR3
8.406e-03	-4.78	Sorb	pfam domains	PF02208	3	1	17795	50	SORBS1
8.476e-03	-4.77	sodium ion transmembrane transporter activity	molecular function	GO:0015081	158	3	18094	48	SLC4A4,SLC1A3,SLC1A2
8.519e-03	-4.77	extracellular region	cellular component	GO:0005576	4350	19	19108	49	PTPRZ1,COL5A3,NTM,SPON1,SLC4A4,FGFR3,GPM6A,LSAMP,CPE,PTGDS,PAMR1,PON2,CST3,CLU,GPC5,NDRG2,APOE,AQP4,SPARCL1
8.525e-03	-4.76	retina development in camera-type eye	biological process	GO:0060041	156	3	18204	49	BMPR1B,GPM6A,NFIA
8.573e-03	-4.76	upper_aerodigestive_tract-larynx-carcinoma-squamous_cell_carcinoma	COSMIC cancer mutations	upper_aerodigestive_tract-larynx-carcinoma-squamous_cell_carcinoma	1946	12	16828	49	MAML2,MACF1,COL5A3,BMPR1B,FGFR3,GLI3,PCDH9,NPAS3,SLC4A4,RYR3,GPM6A,PARD3B
8.641e-03	-4.75	larynx	COSMIC cancer mutations	larynx	1948	12	16828	49	PARD3B,GPM6A,RYR3,NPAS3,SLC4A4,FGFR3,GLI3,PCDH9,COL5A3,BMPR1B,MAML2,MACF1
8.710e-03	-4.74	growth cone	cellular component	GO:0030426	165	3	19108	49	PCDH9,GPM6A,NDRG2
8.711e-03	-4.74	skin-trunk-other-seborrhoeic_keratosis	COSMIC cancer mutations	skin-trunk-other-seborrhoeic_keratosis	3	1	16828	49	FGFR3
8.711e-03	-4.74	lentigo	COSMIC cancer mutations	lentigo	3	1	16828	49	FGFR3
8.711e-03	-4.74	skin-leg-lentigo	COSMIC cancer mutations	skin-leg-lentigo	3	1	16828	49	FGFR3
8.711e-03	-4.74	skin-forearm-lentigo	COSMIC cancer mutations	skin-forearm-lentigo	3	1	16828	49	FGFR3
8.711e-03	-4.74	urinary_tract-bladder-papilloma	COSMIC cancer mutations	urinary_tract-bladder-papilloma	3	1	16828	49	FGFR3
8.711e-03	-4.74	skin-face-lentigo	COSMIC cancer mutations	skin-face-lentigo	3	1	16828	49	FGFR3
8.711e-03	-4.74	skin-trunk-lentigo	COSMIC cancer mutations	skin-trunk-lentigo	3	1	16828	49	FGFR3
8.711e-03	-4.74	skin-hand-lentigo	COSMIC cancer mutations	skin-hand-lentigo	3	1	16828	49	FGFR3
8.711e-03	-4.74	skin-leg-other-seborrhoeic_keratosis	COSMIC cancer mutations	skin-leg-other-seborrhoeic_keratosis	3	1	16828	49	FGFR3
8.711e-03	-4.74	skin-lentigo	COSMIC cancer mutations	skin-lentigo	3	1	16828	49	FGFR3
8.726e-03	-4.74	GLI proteins bind promoters of Hh responsive genes to promote transcription	REACTOME pathways	R-HSA-5635851	3	1	10285	30	GLI3
8.962e-03	-4.71	neutral amino acid transport	biological process	GO:0015804	53	2	18204	49	SLC1A3,SLC1A2
8.979e-03	-4.71	monoatomic anion transport	biological process	GO:0006820	159	3	18204	49	SLC4A4,SLC1A3,SLC1A2
9.087e-03	-4.70	metal ion binding	molecular function	GO:0046872	4239	19	18094	48	RYR3,PON2,DTNA,TRPS1,ATP13A4,SPARCL1,APOE,SLC1A3,GLI3,MACF1,BMPR1B,PAMR1,ABLIM1,SPON1,PCDH9,CPE,GLIS3,AMZ2,SLC1A2
9.095e-03	-4.70	-	gene3d domains	6.10.250.970	3	1	14470	44	MAML2
9.095e-03	-4.70	-	gene3d domains	6.10.250.2510	3	1	14470	44	CTNNA2
9.095e-03	-4.70	Reeler domain	gene3d domains	2.60.40.4060	3	1	14470	44	SPON1
9.095e-03	-4.70	-	gene3d domains	1.10.490.160	3	1	14470	44	RYR3
9.142e-03	-4.69	cervix-carcinoma-squamous_cell_carcinoma	COSMIC cancer mutations	cervix-carcinoma-squamous_cell_carcinoma	11789	42	16828	49	ARHGAP24,NHSL1,CDH20,PAMR1,PREX2,GPM6A,SORBS1,PARD3B,NFIA,TRPS1,MAML2,PON2,ABLIM1,DTNA,COL5A3,ACSS1,FBXL7,FGFR3,GLI3,CST3,PCDH9,AMZ2,NPAS3,MEIS2,ATP13A4,CPE,QKI,SLC4A4,NTM,LSAMP,RYR3,CTNND2,SLC1A2,GPC5,SPARCL1,MACF1,PITPNC1,GLIS3,BMPR1B,PTPRZ1,SPON1,SLC1A3
9.191e-03	-4.69	EF-hand	gene3d domains	1.10.238.10	272	4	14470	44	SPARCL1,MACF1,RYR3,DTNA
9.227e-03	-4.69	cervix	COSMIC cancer mutations	cervix	11793	42	16828	49	ABLIM1,DTNA,MAML2,PON2,PCDH9,AMZ2,FGFR3,CST3,GLI3,COL5A3,FBXL7,ACSS1,NHSL1,CDH20,PAMR1,ARHGAP24,NFIA,TRPS1,PARD3B,GPM6A,SORBS1,PREX2,PITPNC1,MACF1,SPON1,SLC1A3,PTPRZ1,BMPR1B,GLIS3,NTM,ATP13A4,QKI,CPE,SLC4A4,NPAS3,MEIS2,GPC5,SPARCL1,RYR3,CTNND2,SLC1A2,LSAMP
9.290e-03	-4.68	negative regulation of supramolecular fiber organization	biological process	GO:1902904	161	3	18204	49	CLU,CTNNA2,APOE
9.446e-03	-4.66	site of polarized growth	cellular component	GO:0030427	170	3	19108	49	GPM6A,PCDH9,NDRG2
9.513e-03	-4.66	NNT (nicotinamide nucleotide transhydrogenase)	protein interactions	23530	170	3	19454	50	ARHGAP24,PON2,APOE
9.597e-03	-4.65	Neurotransmitter Release Cycle	REACTOME pathways	R-HSA-112310	51	2	10285	30	SLC1A2,SLC1A3
9.613e-03	-4.64	Amyotrophic lateral sclerosis (ALS)	WikiPathways	WP2447	38	2	5310	21	CST3,SLC1A2
9.625e-03	-4.64	intermembrane lipid transfer	biological process	GO:0120009	55	2	18204	49	APOE,PITPNC1
9.625e-03	-4.64	response to cocaine	biological process	GO:0042220	55	2	18204	49	SLC1A2,SLC1A3
9.665e-03	-4.64	TLX1 (T cell leukemia homeobox 1)	protein interactions	3195	171	3	19454	50	NFIA,MEIS2,TRPS1
9.687e-03	-4.64	lipid transfer activity	molecular function	GO:0120013	56	2	18094	48	PITPNC1,APOE
9.929e-03	-4.61	monocarboxylic acid biosynthetic process	biological process	GO:0072330	165	3	18204	49	ACSS1,QKI,PTGDS
1.005e-02	-4.60	organic substance transport	biological process	GO:0071702	1881	11	18204	49	ATP13A4,CPE,GLI3,SLC1A3,MACF1,PITPNC1,APOE,QKI,CLU,SLC4A4,SLC1A2
1.008e-02	-4.60	cellular homeostasis	biological process	GO:0019725	689	6	18204	49	SLC1A3,APOE,RYR3,AQP4,SLC4A4,ATP13A4
1.009e-02	-4.60	HBA1 (hemoglobin subunit alpha 1)	protein interactions	3039	59	2	19454	50	CLU,ARHGAP24
1.009e-02	-4.60	VEGFA (vascular endothelial growth factor A)	protein interactions	7422	59	2	19454	50	CLU,PTPRZ1
1.022e-02	-4.58	extrinsic component of membrane	cellular component	GO:0019898	175	3	19108	49	CTNNA2,DTNA,CDH20
1.022e-02	-4.58	GLI-SUFU complex	cellular component	GO:1990788	4	1	19108	49	GLI3
1.022e-02	-4.58	intermediate-density lipoprotein particle	cellular component	GO:0034363	4	1	19108	49	APOE
1.022e-02	-4.58	collagen type V trimer	cellular component	GO:0005588	4	1	19108	49	COL5A3
1.024e-02	-4.58	Dnaja1 (DnaJ heat shock protein family (Hsp40) member A1)	protein interactions	15502	4	1	19454	50	GLIS3
1.024e-02	-4.58	CCDC126 (coiled-coil domain containing 126)	protein interactions	90693	4	1	19454	50	GPM6A
1.024e-02	-4.58	Ctbp2 (C-terminal binding protein 2)	protein interactions	13017	4	1	19454	50	TRPS1
1.024e-02	-4.58	ZNF879 (zinc finger protein 879)	protein interactions	345462	4	1	19454	50	ARHGAP24
1.024e-02	-4.58	Ilkap (integrin-linked kinase-associated serine/threonine phosphatase 2C)	protein interactions	67444	4	1	19454	50	BMPR1B
1.024e-02	-4.58	Rhebl1 (Ras homolog enriched in brain like 1)	protein interactions	69159	4	1	19454	50	BMPR1B
1.024e-02	-4.58	Arhgef6 (Rac/Cdc42 guanine nucleotide exchange factor 6)	protein interactions	73341	4	1	19454	50	BMPR1B
1.024e-02	-4.58	ZNF615 (zinc finger protein 615)	protein interactions	284370	4	1	19454	50	ARHGAP24
1.024e-02	-4.58	ZNF749 (zinc finger protein 749)	protein interactions	388567	4	1	19454	50	ARHGAP24
1.024e-02	-4.58	Cdk14 (cyclin dependent kinase 14)	protein interactions	18647	4	1	19454	50	BMPR1B
1.024e-02	-4.58	Srgap1 (SLIT-ROBO Rho GTPase activating protein 1)	protein interactions	117600	4	1	19454	50	BMPR1B
1.024e-02	-4.58	Nkiras1 (NFKB inhibitor interacting Ras-like protein 1)	protein interactions	69721	4	1	19454	50	BMPR1B
1.024e-02	-4.58	Naa20 (N(alpha)-acetyltransferase 20, NatB catalytic subunit)	protein interactions	67877	4	1	19454	50	BMPR1B
1.024e-02	-4.58	Sufu (SUFU negative regulator of hedgehog signaling)	protein interactions	24069	4	1	19454	50	GLI3
1.030e-02	-4.58	VINCULIN_1	prosite domains	PS00663	3	1	12186	42	CTNNA2
1.030e-02	-4.58	SOHO	prosite domains	PS50831	3	1	12186	42	SORBS1
1.030e-02	-4.58	MYELIN_PLP_2	prosite domains	PS01004	3	1	12186	42	GPM6A
1.030e-02	-4.58	REELIN	prosite domains	PS51019	3	1	12186	42	SPON1
1.030e-02	-4.58	MYELIN_PLP_1	prosite domains	PS00575	3	1	12186	42	GPM6A
1.031e-02	-4.57	visual behavior	biological process	GO:0007632	57	2	18204	49	SLC1A2,MEIS2
1.034e-02	-4.57	Metabolism of fat-soluble vitamins	REACTOME pathways	R-HSA-6806667	53	2	10285	30	GPC5,APOE
1.042e-02	-4.56	SNTB1 (syntrophin beta 1)	protein interactions	6641	60	2	19454	50	DTNA,FGFR3
1.057e-02	-4.55	acetate-CoA ligase activity	molecular function	GO:0003987	4	1	18094	48	ACSS1
1.057e-02	-4.55	very-low-density lipoprotein particle receptor binding	molecular function	GO:0070326	4	1	18094	48	APOE
1.057e-02	-4.55	ryanodine-sensitive calcium-release channel activity	molecular function	GO:0005219	4	1	18094	48	RYR3
1.057e-02	-4.55	mediator complex binding	molecular function	GO:0036033	4	1	18094	48	GLI3
1.057e-02	-4.55	propionate-CoA ligase activity	molecular function	GO:0050218	4	1	18094	48	ACSS1
1.057e-02	-4.55	short-chain fatty acid-CoA ligase activity	molecular function	GO:0031955	4	1	18094	48	ACSS1
1.061e-02	-4.55	GATA3 (GATA binding protein 3)	protein interactions	2625	177	3	19454	50	QKI,TRPS1,NFIA
1.072e-02	-4.54	regulation of phospholipid efflux	biological process	GO:1902994	4	1	18204	49	APOE
1.072e-02	-4.54	frontal suture morphogenesis	biological process	GO:0060364	4	1	18204	49	GLI3
1.072e-02	-4.54	response to caloric restriction	biological process	GO:0061771	4	1	18204	49	APOE
1.072e-02	-4.54	positive regulation of cardiac muscle myoblast proliferation	biological process	GO:0110024	4	1	18204	49	MEIS2
1.072e-02	-4.54	smoothened signaling pathway involved in dorsal/ventral neural tube patterning	biological process	GO:0060831	4	1	18204	49	GLI3
1.072e-02	-4.54	ovarian cumulus expansion	biological process	GO:0001550	4	1	18204	49	BMPR1B
1.072e-02	-4.54	NMDA glutamate receptor clustering	biological process	GO:0097114	4	1	18204	49	APOE
1.072e-02	-4.54	negative regulation of germ cell proliferation	biological process	GO:1905937	4	1	18204	49	PTGDS
1.072e-02	-4.54	positive regulation of inclusion body assembly	biological process	GO:0090261	4	1	18204	49	CLU
1.072e-02	-4.54	regulation of collagen catabolic process	biological process	GO:0010710	4	1	18204	49	CST3
1.072e-02	-4.54	negative regulation of male germ cell proliferation	biological process	GO:2000255	4	1	18204	49	PTGDS
1.072e-02	-4.54	protein localization to secretory granule	biological process	GO:0033366	4	1	18204	49	CPE
1.072e-02	-4.54	positive regulation of phospholipid efflux	biological process	GO:1902995	4	1	18204	49	APOE
1.072e-02	-4.54	short-chain fatty acid biosynthetic process	biological process	GO:0051790	4	1	18204	49	ACSS1
1.076e-02	-4.53	CTF/NFI_DNA-bd-dom	interpro domains	IPR020604	4	1	18521	50	NFIA
1.076e-02	-4.53	ApoA_E	interpro domains	IPR000074	4	1	18521	50	APOE
1.076e-02	-4.53	Alpha_catenin	interpro domains	IPR001033	4	1	18521	50	CTNNA2
1.076e-02	-4.53	CTF/NFI	interpro domains	IPR000647	4	1	18521	50	NFIA
1.076e-02	-4.53	CTF/NFI_DNA-bd_CS	interpro domains	IPR019739	4	1	18521	50	NFIA
1.076e-02	-4.53	P5B-type_ATPase	interpro domains	IPR047821	4	1	18521	50	ATP13A4
1.076e-02	-4.53	PKNOX/Meis_N	interpro domains	IPR032453	4	1	18521	50	MEIS2
1.076e-02	-4.53	NHS-like	interpro domains	IPR024845	4	1	18521	50	NHSL1
1.076e-02	-4.53	Desmoplakin_Spectrin-like	interpro domains	IPR041573	4	1	18521	50	MACF1
1.076e-02	-4.53	AbLIM_anchor	interpro domains	IPR032402	4	1	18521	50	ABLIM1
1.076e-02	-4.53	Na/K-Atpase_Interacting	interpro domains	IPR008516	4	1	18521	50	NKAIN3
1.076e-02	-4.53	CTF/NFI_DNA-bd_N	interpro domains	IPR019548	4	1	18521	50	NFIA
1.076e-02	-4.53	NDRG	interpro domains	IPR004142	4	1	18521	50	NDRG2
1.076e-02	-4.53	ACAS_N	interpro domains	IPR032387	4	1	18521	50	ACSS1
1.076e-02	-4.53	P5A-ATPase_N	interpro domains	IPR047819	4	1	18521	50	ATP13A4
1.076e-02	-4.53	FGF_rcpt_fam	interpro domains	IPR016248	4	1	18521	50	FGFR3
1.076e-02	-4.53	PCN-like_spectrin-like_rpt	interpro domains	IPR049538	4	1	18521	50	MACF1
1.077e-02	-4.53	MamL-1	smart domains	SM01275	3	1	9717	35	MAML2
1.077e-02	-4.53	Sorb	smart domains	SM00459	3	1	9717	35	SORBS1
1.077e-02	-4.53	PLP	smart domains	SM00002	3	1	9717	35	GPM6A
1.082e-02	-4.53	skeletal system development	biological process	GO:0001501	500	5	18204	49	TRPS1,BMPR1B,NFIA,FGFR3,GLI3
1.098e-02	-4.51	bone-tibia-Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour	COSMIC cancer mutations	bone-tibia-Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour	649	6	16828	49	ABLIM1,QKI,MACF1,ACSS1,PREX2,FGFR3
1.098e-02	-4.51	primitive_neuroectodermal_tumour-medulloblastoma	COSMIC cancer mutations	primitive_neuroectodermal_tumour-medulloblastoma	15350	49	16828	49	PITPNC1,MACF1,NDRG2,PTPRZ1,SPON1,SLC1A3,GLIS3,NTM,NPAS3,MEIS2,QKI,ATP13A4,SLC4A4,GPC5,CTNND2,APOE,PON2,DTNA,FGFR3,GLI3,PCDH9,AMZ2,NKAIN3,ARHGAP24,CDH20,PARD3B,PREX2,BMPR1B,AQP4,CPE,SPARCL1,LSAMP,RYR3,SLC1A2,MAML2,CLU,ABLIM1,CST3,COL5A3,FBXL7,ACSS1,NHSL1,PAMR1,MSI2,PTGDS,NFIA,TRPS1,GPM6A,SORBS1
1.101e-02	-4.51	endochondral bone morphogenesis	biological process	GO:0060350	59	2	18204	49	BMPR1B,FGFR3
1.104e-02	-4.51	EZR (ezrin)	protein interactions	7430	526	5	19454	50	ABLIM1,ARHGAP24,MACF1,DTNA,SORBS1
1.107e-02	-4.50	inorganic molecular entity transmembrane transporter activity	molecular function	GO:0015318	714	6	18094	48	RYR3,SLC4A4,SLC1A3,AQP4,GPM6A,SLC1A2
1.118e-02	-4.49	parietal_lobe	COSMIC cancer mutations	parietal_lobe	55	2	16828	49	FGFR3,QKI
1.119e-02	-4.49	ACAS_N	pfam domains	PF16177	4	1	17795	50	ACSS1
1.119e-02	-4.49	Spectrin_2	pfam domains	PF18373	4	1	17795	50	MACF1
1.119e-02	-4.49	AbLIM_anchor	pfam domains	PF16182	4	1	17795	50	ABLIM1
1.119e-02	-4.49	Ndr	pfam domains	PF03096	4	1	17795	50	NDRG2
1.119e-02	-4.49	Spectrin_3	pfam domains	PF21019	4	1	17795	50	MACF1
1.119e-02	-4.49	Apolipoprotein	pfam domains	PF01442	4	1	17795	50	APOE
1.119e-02	-4.49	Spectrin_4	pfam domains	PF21020	4	1	17795	50	MACF1
1.119e-02	-4.49	NfI_DNAbd_pre-N	pfam domains	PF10524	4	1	17795	50	NFIA
1.119e-02	-4.49	P5-ATPase	pfam domains	PF12409	4	1	17795	50	ATP13A4
1.119e-02	-4.49	CTF_NFI	pfam domains	PF00859	4	1	17795	50	NFIA
1.119e-02	-4.49	NKAIN	pfam domains	PF05640	4	1	17795	50	NKAIN3
1.119e-02	-4.49	NHS	pfam domains	PF15273	4	1	17795	50	NHSL1
1.119e-02	-4.49	Meis_PKNOX_N	pfam domains	PF16493	4	1	17795	50	MEIS2
1.121e-02	-4.49	YWHAB (tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein beta)	protein interactions	7529	965	7	19454	50	PARD3B,MACF1,ABLIM1,SORBS1,PITPNC1,NHSL1,FGFR3
1.126e-02	-4.49	monoatomic cation homeostasis	biological process	GO:0055080	505	5	18204	49	SLC4A4,ATP13A4,APOE,RYR3,SLC1A3
1.128e-02	-4.48	regulation of cell size	biological process	GO:0008361	173	3	18204	49	APOE,MACF1,AQP4
1.137e-02	-4.48	regulation of glucose import	biological process	GO:0046324	60	2	18204	49	SORBS1,SLC1A2
1.137e-02	-4.48	protein homotetramerization	biological process	GO:0051289	60	2	18204	49	AQP4,RYR3
1.143e-02	-4.47	human chr14q13.1	chromosome location	human chr14q13.1	6	1	26134	50	NPAS3
1.143e-02	-4.47	human chr4q34.2	chromosome location	human chr4q34.2	6	1	26134	50	GPM6A
1.144e-02	-4.47	MYELINPLP	prints domains	PR00214	3	1	5227	20	GPM6A
1.144e-02	-4.47	RYANODINER	prints domains	PR00795	3	1	5227	20	RYR3
1.144e-02	-4.47	PGNDSYNTHASE	prints domains	PR01254	3	1	5227	20	PTGDS
1.144e-02	-4.47	PARAOXONASE	prints domains	PR01785	3	1	5227	20	PON2
1.153e-02	-4.46	response to endogenous stimulus	biological process	GO:0009719	1402	9	18204	49	SLC1A2,BMPR1B,NFIA,FGFR3,PTGDS,SLC1A3,SORBS1,MEIS2,RYR3
1.156e-02	-4.46	oligodendroglioma_Grade_III	COSMIC cancer mutations	oligodendroglioma_Grade_III	303	4	16828	49	FGFR3,PTPRZ1,MACF1,GLIS3
1.160e-02	-4.46	urinary_tract-bladder-other-normal	COSMIC cancer mutations	urinary_tract-bladder-other-normal	4	1	16828	49	FGFR3
1.160e-02	-4.46	inverted	COSMIC cancer mutations	inverted	4	1	16828	49	FGFR3
1.160e-02	-4.46	skin-face-malignant_melanoma-superficial_spreading	COSMIC cancer mutations	skin-face-malignant_melanoma-superficial_spreading	4	1	16828	49	PREX2
1.160e-02	-4.46	skin-lower_leg-malignant_melanoma-nodular	COSMIC cancer mutations	skin-lower_leg-malignant_melanoma-nodular	4	1	16828	49	PREX2
1.160e-02	-4.46	urinary_tract-bladder-papilloma-inverted	COSMIC cancer mutations	urinary_tract-bladder-papilloma-inverted	4	1	16828	49	FGFR3
1.160e-02	-4.46	skin-benign_melanocytic_nevus-junctional	COSMIC cancer mutations	skin-benign_melanocytic_nevus-junctional	4	1	16828	49	FGFR3
1.179e-02	-4.44	COL1A2 (collagen type I alpha 2 chain)	protein interactions	1278	64	2	19454	50	COL5A3,ARHGAP24
1.179e-02	-4.44	SYNC (syncoilin, intermediate filament protein)	protein interactions	81493	64	2	19454	50	MAML2,DTNA
1.179e-02	-4.44	VSX1 (visual system homeobox 1)	protein interactions	30813	64	2	19454	50	TRPS1,NFIA
1.179e-02	-4.44	EVA1C (eva-1 homolog C)	protein interactions	59271	64	2	19454	50	BMPR1B,PCDH9
1.184e-02	-4.44	cadherin binding	molecular function	GO:0045296	335	4	18094	48	MACF1,CTNNA2,CTNND2,CDH20
1.190e-02	-4.43	biliary_tract-gallbladder-carcinoma-adenocarcinoma	COSMIC cancer mutations	biliary_tract-gallbladder-carcinoma-adenocarcinoma	2821	15	16828	49	SLC4A4,NHSL1,CTNND2,RYR3,PREX2,TRPS1,SPARCL1,CLU,MACF1,PITPNC1,COL5A3,NKAIN3,PCDH9,PTPRZ1,FGFR3
1.190e-02	-4.43	gallbladder	COSMIC cancer mutations	gallbladder	2821	15	16828	49	NHSL1,SLC4A4,SPARCL1,TRPS1,CTNND2,RYR3,PREX2,PITPNC1,CLU,MACF1,NKAIN3,PCDH9,PTPRZ1,FGFR3,COL5A3
1.211e-02	-4.41	-	gene3d domains	1.20.58.1060	4	1	14470	44	MACF1
1.213e-02	-4.41	Transmembrane transport of small molecules	REACTOME pathways	R-HSA-382551	677	6	10285	30	AQP4,ATP13A4,SLC1A2,RYR3,SLC4A4,SLC1A3
1.218e-02	-4.41	monoatomic ion homeostasis	biological process	GO:0050801	515	5	18204	49	ATP13A4,SLC4A4,SLC1A3,RYR3,APOE
1.230e-02	-4.40	KLF5 (KLF transcription factor 5)	protein interactions	688	187	3	19454	50	TRPS1,CLU,NFIA
1.245e-02	-4.39	camera-type eye development	biological process	GO:0043010	335	4	18204	49	BMPR1B,GPM6A,GLI3,NFIA
1.249e-02	-4.38	regulation of nitric oxide biosynthetic process	biological process	GO:0045428	63	2	18204	49	APOE,CLU
1.250e-02	-4.38	MICB (MHC class I polypeptide-related sequence B)	protein interactions	4277	66	2	19454	50	APOE,CLU
1.250e-02	-4.38	MAML1 (mastermind like transcriptional coactivator 1)	protein interactions	9794	66	2	19454	50	NFIA,MAML2
1.250e-02	-4.38	ORM1 (orosomucoid 1)	protein interactions	5004	66	2	19454	50	CLU,PTGDS
1.250e-02	-4.38	KATNA1 (katanin catalytic subunit A1)	protein interactions	11104	66	2	19454	50	ARHGAP24,CLU
1.265e-02	-4.37	brain development	biological process	GO:0007420	724	6	18204	49	SLC1A2,NDRG2,CTNNA2,MEIS2,GLI3,PCDH9
1.269e-02	-4.37	Arachidonic acid metabolism	REACTOME pathways	R-HSA-2142753	59	2	10285	30	PON2,PTGDS
1.276e-02	-4.36	neurofibrillary tangle	cellular component	GO:0097418	5	1	19108	49	CLU
1.279e-02	-4.36	EPPIN (epididymal peptidase inhibitor)	protein interactions	57119	5	1	19454	50	CLU
1.279e-02	-4.36	Rhoj (ras homolog family member J)	protein interactions	80837	5	1	19454	50	BMPR1B
1.279e-02	-4.36	TRPM6 (transient receptor potential cation channel subfamily M member 6)	protein interactions	140803	5	1	19454	50	ARHGAP24
1.279e-02	-4.36	POU2F3 (POU class 2 homeobox 3)	protein interactions	25833	5	1	19454	50	ARHGAP24
1.279e-02	-4.36	ZNF93 (zinc finger protein 93)	protein interactions	81931	5	1	19454	50	ARHGAP24
1.279e-02	-4.36	Rab38 (RAB38, member RAS oncogene family)	protein interactions	72433	5	1	19454	50	BMPR1B
1.279e-02	-4.36	ZNF571 (zinc finger protein 571)	protein interactions	51276	5	1	19454	50	ARHGAP24
1.279e-02	-4.36	Rras2 (related RAS viral (r-ras) oncogene 2)	protein interactions	66922	5	1	19454	50	BMPR1B
1.279e-02	-4.36	Hk3 (hexokinase 3)	protein interactions	25060	5	1	19454	50	PTGDS
1.279e-02	-4.36	ADCYAP1R1 (ADCYAP receptor type I)	protein interactions	117	5	1	19454	50	CLU
1.279e-02	-4.36	Rab6b (RAB6B, member RAS oncogene family)	protein interactions	270192	5	1	19454	50	BMPR1B
1.279e-02	-4.36	Rhobtb1 (Rho-related BTB domain containing 1)	protein interactions	69288	5	1	19454	50	BMPR1B
1.279e-02	-4.36	TRH (thyrotropin releasing hormone)	protein interactions	7200	5	1	19454	50	CPE
1.279e-02	-4.36	Wwp2 (WW domain containing E3 ubiquitin protein ligase 2)	protein interactions	66894	5	1	19454	50	GLIS3
1.279e-02	-4.36	SLC10A3 (solute carrier family 10 member 3)	protein interactions	8273	5	1	19454	50	SORBS1
1.279e-02	-4.36	ZNF836 (zinc finger protein 836)	protein interactions	162962	5	1	19454	50	ARHGAP24
1.279e-02	-4.36	Cdk4 (cyclin dependent kinase 4)	protein interactions	12567	5	1	19454	50	BMPR1B
1.279e-02	-4.36	PTGER2 (prostaglandin E receptor 2)	protein interactions	5732	5	1	19454	50	PTGDS
1.287e-02	-4.35	cranial nerve development	biological process	GO:0021545	64	2	18204	49	SLC1A3,GLI3
1.310e-02	-4.34	medullomyoblastoma	COSMIC cancer mutations	medullomyoblastoma	485	5	16828	49	PCDH9,ATP13A4,RYR3,SLC4A4,LSAMP
1.310e-02	-4.34	central_nervous_system-brain-primitive_neuroectodermal_tumour-medulloblastoma-medullomyoblastoma	COSMIC cancer mutations	central_nervous_system-brain-primitive_neuroectodermal_tumour-medulloblastoma-medullomyoblastoma	485	5	16828	49	RYR3,ATP13A4,SLC4A4,LSAMP,PCDH9
1.311e-02	-4.33	Signaling by BRAF and RAF fusions	REACTOME pathways	R-HSA-6802952	60	2	10285	30	MACF1,QKI
1.317e-02	-4.33	upper_leg	COSMIC cancer mutations	upper_leg	880	7	16828	49	PAMR1,FGFR3,PCDH9,NFIA,PREX2,ACSS1,GLIS3
1.320e-02	-4.33	fibroblast growth factor receptor activity	molecular function	GO:0005007	5	1	18094	48	FGFR3
1.320e-02	-4.33	transforming growth factor beta receptor activity, type I	molecular function	GO:0005025	5	1	18094	48	BMPR1B
1.325e-02	-4.32	regulation of nitric oxide metabolic process	biological process	GO:0080164	65	2	18204	49	APOE,CLU
1.327e-02	-4.32	L-amino acid transmembrane transporter activity	molecular function	GO:0015179	66	2	18094	48	SLC1A2,SLC1A3
1.332e-02	-4.32	human chr13q21.32	chromosome location	human chr13q21.32	7	1	26134	50	PCDH9
1.332e-02	-4.32	human chr8q13.2	chromosome location	human chr8q13.2	7	1	26134	50	PREX2
1.339e-02	-4.31	PHIP (pleckstrin homology domain interacting protein)	protein interactions	55023	193	3	19454	50	CLU,GLI3,TRPS1
1.339e-02	-4.31	propionate metabolic process	biological process	GO:0019541	5	1	18204	49	ACSS1
1.339e-02	-4.31	AMPA glutamate receptor clustering	biological process	GO:0097113	5	1	18204	49	APOE
1.339e-02	-4.31	positive regulation of dendritic spine maintenance	biological process	GO:1902952	5	1	18204	49	APOE
1.339e-02	-4.31	central nervous system myelin maintenance	biological process	GO:0032286	5	1	18204	49	CLU
1.339e-02	-4.31	glutamate receptor clustering	biological process	GO:0097688	5	1	18204	49	APOE
1.339e-02	-4.31	negative regulation of Rac protein signal transduction	biological process	GO:0035021	5	1	18204	49	ARHGAP24
1.339e-02	-4.31	negative regulation of chondrocyte proliferation	biological process	GO:1902731	5	1	18204	49	BMPR1B
1.339e-02	-4.31	chylomicron remnant clearance	biological process	GO:0034382	5	1	18204	49	APOE
1.343e-02	-4.31	PI_transfer	interpro domains	IPR001666	5	1	18521	50	PITPNC1
1.343e-02	-4.31	Vinculin/catenin	interpro domains	IPR006077	5	1	18521	50	CTNNA2
1.343e-02	-4.31	Protocadherin	interpro domains	IPR013585	5	1	18521	50	PCDH9
1.343e-02	-4.31	Na/HCO3_transpt	interpro domains	IPR003024	5	1	18521	50	SLC4A4
1.343e-02	-4.31	P-type_TPase_V	interpro domains	IPR006544	5	1	18521	50	ATP13A4
1.343e-02	-4.31	Follistatin/Osteonectin_EGF	interpro domains	IPR015369	5	1	18521	50	SPARCL1
1.343e-02	-4.31	BBP-like	interpro domains	IPR045071	5	1	18521	50	QKI
1.356e-02	-4.30	arm	COSMIC cancer mutations	arm	1331	9	16828	49	NTM,SLC4A4,MACF1,NPAS3,TRPS1,PARD3B,FGFR3,SORBS1,COL5A3
1.364e-02	-4.29	L-alpha-amino acid transmembrane transport	biological process	GO:1902475	66	2	18204	49	SLC1A2,SLC1A3
1.367e-02	-4.29	neoplasm	COSMIC cancer mutations	neoplasm	14787	48	16828	49	SPON1,SLC1A3,NDRG2,PTPRZ1,GLIS3,MACF1,GPC5,CTNND2,NTM,QKI,ATP13A4,SLC4A4,MEIS2,NPAS3,PCDH9,NKAIN3,AMZ2,GLI3,FGFR3,APOE,DTNA,PON2,PARD3B,PREX2,CDH20,ARHGAP24,BMPR1B,SPARCL1,RYR3,SLC1A2,LSAMP,AQP4,CPE,CST3,COL5A3,FBXL7,ACSS1,CLU,ABLIM1,MAML2,NFIA,TRPS1,GPM6A,SORBS1,NHSL1,PAMR1,MSI2,PTGDS
1.372e-02	-4.29	CTF_NFI_1	prosite domains	PS00349	4	1	12186	42	NFIA
1.372e-02	-4.29	CTF_NFI_2	prosite domains	PS51080	4	1	12186	42	NFIA
1.375e-02	-4.29	right_upper_lobe	COSMIC cancer mutations	right_upper_lobe	10376	38	16828	49	CDH20,PAMR1,ARHGAP24,GPM6A,SORBS1,PREX2,NFIA,TRPS1,PARD3B,ABLIM1,DTNA,PON2,APOE,COL5A3,FBXL7,PCDH9,NKAIN3,FGFR3,GLI3,CPE,ATP13A4,SLC4A4,NPAS3,MEIS2,NTM,RYR3,CTNND2,SLC1A2,LSAMP,GPC5,MACF1,PITPNC1,BMPR1B,GLIS3,SPON1,SLC1A3,PTPRZ1,NDRG2
1.375e-02	-4.29	lung-right_upper_lobe-carcinoma-adenocarcinoma	COSMIC cancer mutations	lung-right_upper_lobe-carcinoma-adenocarcinoma	10376	38	16828	49	PON2,DTNA,ABLIM1,APOE,FBXL7,COL5A3,GLI3,FGFR3,NKAIN3,PCDH9,ARHGAP24,CDH20,PAMR1,PREX2,SORBS1,GPM6A,PARD3B,TRPS1,NFIA,MACF1,PITPNC1,GLIS3,BMPR1B,PTPRZ1,NDRG2,SLC1A3,SPON1,MEIS2,NPAS3,SLC4A4,CPE,ATP13A4,NTM,LSAMP,CTNND2,SLC1A2,RYR3,GPC5
1.397e-02	-4.27	FOLN	pfam domains	PF09289	5	1	17795	50	SPARCL1
1.397e-02	-4.27	IP_trans	pfam domains	PF02121	5	1	17795	50	PITPNC1
1.397e-02	-4.27	Vinculin	pfam domains	PF01044	5	1	17795	50	CTNNA2
1.397e-02	-4.27	Protocadherin	pfam domains	PF08374	5	1	17795	50	PCDH9
1.399e-02	-4.27	PCDH20 (protocadherin 20)	protein interactions	64881	70	2	19454	50	PON2,CTNNA2
1.400e-02	-4.27	adenoma	COSMIC cancer mutations	adenoma	2873	15	16828	49	APOE,MACF1,PTPRZ1,FGFR3,GLI3,PCDH9,ACSS1,COL5A3,BMPR1B,CDH20,NPAS3,GPC5,CTNND2,RYR3,GPM6A
1.403e-02	-4.27	monoatomic ion transmembrane transporter activity	molecular function	GO:0015075	752	6	18094	48	ATP13A4,SLC4A4,SLC1A3,RYR3,GPM6A,SLC1A2
1.404e-02	-4.27	cholesterol transport	biological process	GO:0030301	67	2	18204	49	CLU,APOE
1.404e-02	-4.27	collagen binding	molecular function	GO:0005518	68	2	18094	48	COL5A3,SPARCL1
1.410e-02	-4.26	protein processing	biological process	GO:0016485	188	3	18204	49	SPON1,CPE,GLI3
1.418e-02	-4.26	hepatocellular_carcinoma	COSMIC cancer mutations	hepatocellular_carcinoma	14800	48	16828	49	ATP13A4,QKI,SLC4A4,MEIS2,NPAS3,NTM,CTNND2,GPC5,MACF1,PITPNC1,GLIS3,SPON1,SLC1A3,NDRG2,PTPRZ1,CDH20,ARHGAP24,PREX2,PARD3B,DTNA,PON2,APOE,PCDH9,AMZ2,NKAIN3,FGFR3,GLI3,AQP4,CPE,RYR3,SLC1A2,LSAMP,SPARCL1,BMPR1B,PTGDS,NHSL1,PAMR1,GPM6A,SORBS1,NFIA,TRPS1,CLU,ABLIM1,MAML2,COL5A3,ACSS1,FBXL7,CST3
1.418e-02	-4.26	liver-carcinoma-hepatocellular_carcinoma	COSMIC cancer mutations	liver-carcinoma-hepatocellular_carcinoma	14800	48	16828	49	PTGDS,NHSL1,PAMR1,GPM6A,SORBS1,NFIA,TRPS1,MAML2,ABLIM1,CLU,COL5A3,ACSS1,FBXL7,CST3,CPE,AQP4,LSAMP,RYR3,SLC1A2,SPARCL1,BMPR1B,ARHGAP24,CDH20,PREX2,PARD3B,PON2,DTNA,APOE,FGFR3,GLI3,PCDH9,NKAIN3,AMZ2,MEIS2,NPAS3,QKI,ATP13A4,SLC4A4,NTM,CTNND2,GPC5,MACF1,PITPNC1,GLIS3,PTPRZ1,NDRG2,SPON1,SLC1A3
1.433e-02	-4.25	VAC14 (VAC14 component of PIKFYVE complex)	protein interactions	55697	198	3	19454	50	QKI,ACSS1,ARHGAP24
1.448e-02	-4.24	skin-other-lichenoid_keratosis	COSMIC cancer mutations	skin-other-lichenoid_keratosis	5	1	16828	49	FGFR3
1.448e-02	-4.24	skin-face-other-nevus_sebaceous	COSMIC cancer mutations	skin-face-other-nevus_sebaceous	5	1	16828	49	FGFR3
1.448e-02	-4.24	skin-upper_leg-other-lichenoid_keratosis	COSMIC cancer mutations	skin-upper_leg-other-lichenoid_keratosis	5	1	16828	49	FGFR3
1.448e-02	-4.24	skin-shoulder-other-nevus_sebaceous	COSMIC cancer mutations	skin-shoulder-other-nevus_sebaceous	5	1	16828	49	FGFR3
1.448e-02	-4.24	skin-scalp-other-nevus_sebaceous	COSMIC cancer mutations	skin-scalp-other-nevus_sebaceous	5	1	16828	49	FGFR3
1.448e-02	-4.24	skin-chest-other-lichenoid_keratosis	COSMIC cancer mutations	skin-chest-other-lichenoid_keratosis	5	1	16828	49	FGFR3
1.448e-02	-4.24	syringocystadenoma_papilliferum	COSMIC cancer mutations	syringocystadenoma_papilliferum	5	1	16828	49	FGFR3
1.448e-02	-4.24	skin-breast-other-nevus_sebaceous	COSMIC cancer mutations	skin-breast-other-nevus_sebaceous	5	1	16828	49	FGFR3
1.448e-02	-4.24	skin-lower_back-other-lichenoid_keratosis	COSMIC cancer mutations	skin-lower_back-other-lichenoid_keratosis	5	1	16828	49	FGFR3
1.448e-02	-4.24	skin-lower_leg-other-lichenoid_keratosis	COSMIC cancer mutations	skin-lower_leg-other-lichenoid_keratosis	5	1	16828	49	FGFR3
1.448e-02	-4.24	skin-shoulder-other-lichenoid_keratosis	COSMIC cancer mutations	skin-shoulder-other-lichenoid_keratosis	5	1	16828	49	FGFR3
1.448e-02	-4.24	skin-adnexal_tumour-syringocystadenoma_papilliferum	COSMIC cancer mutations	skin-adnexal_tumour-syringocystadenoma_papilliferum	5	1	16828	49	FGFR3
1.448e-02	-4.24	skin-upper_arm-other-lichenoid_keratosis	COSMIC cancer mutations	skin-upper_arm-other-lichenoid_keratosis	5	1	16828	49	FGFR3
1.448e-02	-4.24	skin-forearm-other-seborrhoeic_keratosis	COSMIC cancer mutations	skin-forearm-other-seborrhoeic_keratosis	5	1	16828	49	FGFR3
1.448e-02	-4.24	skin-forearm-other-lichenoid_keratosis	COSMIC cancer mutations	skin-forearm-other-lichenoid_keratosis	5	1	16828	49	FGFR3
1.448e-02	-4.24	monoclonal_gammopathy_of_undetermined_significance	COSMIC cancer mutations	monoclonal_gammopathy_of_undetermined_significance	5	1	16828	49	FGFR3
1.448e-02	-4.24	skin-neck-other-lichenoid_keratosis	COSMIC cancer mutations	skin-neck-other-lichenoid_keratosis	5	1	16828	49	FGFR3
1.448e-02	-4.24	skin-breast-other-lichenoid_keratosis	COSMIC cancer mutations	skin-breast-other-lichenoid_keratosis	5	1	16828	49	FGFR3
1.448e-02	-4.24	skin-flank-other-lichenoid_keratosis	COSMIC cancer mutations	skin-flank-other-lichenoid_keratosis	5	1	16828	49	FGFR3
1.448e-02	-4.24	skin-lower_back-other-nevus_sebaceous	COSMIC cancer mutations	skin-lower_back-other-nevus_sebaceous	5	1	16828	49	FGFR3
1.448e-02	-4.24	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-monoclonal_gammopathy_of_undetermined_significance	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-monoclonal_gammopathy_of_undetermined_significance	5	1	16828	49	FGFR3
1.448e-02	-4.24	skin-neck-other-nevus_sebaceous	COSMIC cancer mutations	skin-neck-other-nevus_sebaceous	5	1	16828	49	FGFR3
1.448e-02	-4.24	skin-arm-other-seborrhoeic_keratosis	COSMIC cancer mutations	skin-arm-other-seborrhoeic_keratosis	5	1	16828	49	FGFR3
1.448e-02	-4.24	lichenoid_keratosis	COSMIC cancer mutations	lichenoid_keratosis	5	1	16828	49	FGFR3
1.448e-02	-4.24	skin-ear-other-nevus_sebaceous	COSMIC cancer mutations	skin-ear-other-nevus_sebaceous	5	1	16828	49	FGFR3
1.448e-02	-4.24	skin-lower_leg-malignant_melanoma-superficial_spreading	COSMIC cancer mutations	skin-lower_leg-malignant_melanoma-superficial_spreading	5	1	16828	49	PREX2
1.448e-02	-4.24	skin-upper_back-other-lichenoid_keratosis	COSMIC cancer mutations	skin-upper_back-other-lichenoid_keratosis	5	1	16828	49	FGFR3
1.448e-02	-4.24	skin-hand-other-lichenoid_keratosis	COSMIC cancer mutations	skin-hand-other-lichenoid_keratosis	5	1	16828	49	FGFR3
1.448e-02	-4.24	skin-hip-other-seborrhoeic_keratosis	COSMIC cancer mutations	skin-hip-other-seborrhoeic_keratosis	5	1	16828	49	FGFR3
1.448e-02	-4.24	skin-face-other-lichenoid_keratosis	COSMIC cancer mutations	skin-face-other-lichenoid_keratosis	5	1	16828	49	FGFR3
1.476e-02	-4.22	PPP3CC (protein phosphatase 3 catalytic subunit gamma)	protein interactions	5533	72	2	19454	50	BMPR1B,PARD3B
1.508e-02	-4.19	upper_back	COSMIC cancer mutations	upper_back	328	4	16828	49	MACF1,GPC5,PARD3B,FGFR3
1.511e-02	-4.19	Apolipoprotein	gene3d domains	1.20.120.20	5	1	14470	44	APOE
1.521e-02	-4.19	plasma membrane region	cellular component	GO:0098590	1278	8	19108	49	SLC4A4,GPM6A,AQP4,SORBS1,PARD3B,SLC1A3,MACF1,SLC1A2
1.522e-02	-4.19	ALPHACATENIN	prints domains	PR00805	4	1	5227	20	CTNNA2
1.526e-02	-4.18	negative regulation of smooth muscle cell proliferation	biological process	GO:0048662	70	2	18204	49	NDRG2,APOE
1.527e-02	-4.18	Ethanol Degradation	SMPDB pathways	SMP0000449	7	1	1369	3	ACSS1
1.529e-02	-4.18	multivesicular body, internal vesicle	cellular component	GO:0097487	6	1	19108	49	APOE
1.532e-02	-4.18	FGF6 (fibroblast growth factor 6)	protein interactions	2251	6	1	19454	50	FGFR3
1.532e-02	-4.18	Map2k3 (mitogen-activated protein kinase kinase 3)	protein interactions	26397	6	1	19454	50	BMPR1B
1.532e-02	-4.18	PBP2 (Pbp2p)	protein interactions	852533	6	1	19454	50	QKI
1.532e-02	-4.18	LCAT (lecithin-cholesterol acyltransferase)	protein interactions	3931	6	1	19454	50	APOE
1.532e-02	-4.18	ZNF311 (zinc finger protein 311)	protein interactions	282890	6	1	19454	50	ARHGAP24
1.532e-02	-4.18	Itch (itchy, E3 ubiquitin protein ligase)	protein interactions	16396	6	1	19454	50	GLIS3
1.532e-02	-4.18	Tiam2 (T cell lymphoma invasion and metastasis 2)	protein interactions	24001	6	1	19454	50	DTNA
1.532e-02	-4.18	FGF23 (fibroblast growth factor 23)	protein interactions	8074	6	1	19454	50	FGFR3
1.532e-02	-4.18	FGF18 (fibroblast growth factor 18)	protein interactions	8817	6	1	19454	50	FGFR3
1.532e-02	-4.18	SLC12A5 (solute carrier family 12 member 5)	protein interactions	57468	6	1	19454	50	GPM6A
1.532e-02	-4.18	DRP2 (dystrophin related protein 2)	protein interactions	1821	6	1	19454	50	DTNA
1.532e-02	-4.18	Taok2 (TAO kinase 2)	protein interactions	381921	6	1	19454	50	CLU
1.532e-02	-4.18	GDF6 (growth differentiation factor 6)	protein interactions	392255	6	1	19454	50	BMPR1B
1.532e-02	-4.18	DAZ4 (deleted in azoospermia 4)	protein interactions	57135	6	1	19454	50	QKI
1.532e-02	-4.18	Rhod (ras homolog family member D)	protein interactions	11854	6	1	19454	50	BMPR1B
1.532e-02	-4.18	CYRIA (CYFIP related Rac1 interactor A)	protein interactions	81553	6	1	19454	50	GPM6A
1.532e-02	-4.18	Fancl (Fanconi anemia, complementation group L)	protein interactions	67030	6	1	19454	50	BMPR1B
1.532e-02	-4.18	Zbtb2 (zinc finger and BTB domain containing 2)	protein interactions	381990	6	1	19454	50	SORBS1
1.532e-02	-4.18	FXYD7 (FXYD domain containing ion transport regulator 7)	protein interactions	53822	6	1	19454	50	APOE
1.533e-02	-4.18	protein homooligomerization	biological process	GO:0051260	194	3	18204	49	AQP4,SLC1A2,RYR3
1.535e-02	-4.18	cell-cell adhesion	biological process	GO:0098609	546	5	18204	49	PCDH9,CDH20,CTNNA2,SPARCL1,CTNND2
1.552e-02	-4.17	CASK (calcium/calmodulin dependent serine protein kinase)	protein interactions	8573	204	3	19454	50	PARD3B,DTNA,ABLIM1
1.554e-02	-4.16	bone development	biological process	GO:0060348	195	3	18204	49	GLI3,FGFR3,BMPR1B
1.554e-02	-4.16	CACNA2D1 (calcium voltage-gated channel auxiliary subunit alpha2delta 1)	protein interactions	781	74	2	19454	50	PON2,GPM6A
1.581e-02	-4.15	calcium-induced calcium release activity	molecular function	GO:0048763	6	1	18094	48	RYR3
1.581e-02	-4.15	arylesterase activity	molecular function	GO:0004064	6	1	18094	48	PON2
1.581e-02	-4.15	sodium:bicarbonate symporter activity	molecular function	GO:0008510	6	1	18094	48	SLC4A4
1.581e-02	-4.15	phosphatidylcholine-sterol O-acyltransferase activator activity	molecular function	GO:0060228	6	1	18094	48	APOE
1.590e-02	-4.14	animal organ morphogenesis	biological process	GO:0009887	988	7	18204	49	FGFR3,CPE,GLI3,ABLIM1,CTNNA2,MEIS2,BMPR1B
1.600e-02	-4.13	other	COSMIC cancer mutations	other	14843	48	16828	49	MAML2,ABLIM1,CLU,COL5A3,ACSS1,FBXL7,CST3,PTGDS,NHSL1,MSI2,PAMR1,GPM6A,SORBS1,NFIA,TRPS1,BMPR1B,AQP4,CPE,LSAMP,RYR3,SLC1A2,SPARCL1,PON2,DTNA,APOE,FGFR3,GLI3,PCDH9,AMZ2,NKAIN3,ARHGAP24,CDH20,PREX2,PARD3B,MACF1,GLIS3,PTPRZ1,NDRG2,SPON1,SLC1A3,NPAS3,MEIS2,QKI,ATP13A4,SLC4A4,NTM,CTNND2,GPC5
1.604e-02	-4.13	regulation of low-density lipoprotein particle receptor catabolic process	biological process	GO:0032803	6	1	18204	49	APOE
1.604e-02	-4.13	protein targeting to vacuole involved in autophagy	biological process	GO:0071211	6	1	18204	49	CLU
1.604e-02	-4.13	optic nerve morphogenesis	biological process	GO:0021631	6	1	18204	49	GLI3
1.604e-02	-4.13	intracellular water homeostasis	biological process	GO:0009992	6	1	18204	49	AQP4
1.604e-02	-4.13	gamma-aminobutyric acid biosynthetic process	biological process	GO:0009449	6	1	18204	49	SLC1A3
1.604e-02	-4.13	negative regulation of extracellular matrix disassembly	biological process	GO:0010716	6	1	18204	49	CST3
1.604e-02	-4.13	fused antrum stage	biological process	GO:0048165	6	1	18204	49	BMPR1B
1.604e-02	-4.13	vascular associated smooth muscle cell proliferation	biological process	GO:1990874	6	1	18204	49	NDRG2
1.604e-02	-4.13	mammary gland formation	biological process	GO:0060592	6	1	18204	49	GLI3
1.604e-02	-4.13	triglyceride-rich lipoprotein particle clearance	biological process	GO:0071830	6	1	18204	49	APOE
1.609e-02	-4.13	RyR/IP3R_RIH_dom_sf	interpro domains	IPR035910	6	1	18521	50	RYR3
1.609e-02	-4.13	Desmoplakin_SH3	interpro domains	IPR041615	6	1	18521	50	MACF1
1.609e-02	-4.13	RIH_assoc-dom	interpro domains	IPR013662	6	1	18521	50	RYR3
1.609e-02	-4.13	TSP1_spondin_dom	interpro domains	IPR044004	6	1	18521	50	SPON1
1.609e-02	-4.13	Ryanodine_IP3_receptor	interpro domains	IPR015925	6	1	18521	50	RYR3
1.609e-02	-4.13	Glypican_CS	interpro domains	IPR019803	6	1	18521	50	GPC5
1.609e-02	-4.13	EF-hand_dom_typ1	interpro domains	IPR015153	6	1	18521	50	DTNA
1.609e-02	-4.13	Glypican	interpro domains	IPR001863	6	1	18521	50	GPC5
1.609e-02	-4.13	GAR_dom	interpro domains	IPR003108	6	1	18521	50	MACF1
1.609e-02	-4.13	Ins145_P3_rcpt	interpro domains	IPR014821	6	1	18521	50	RYR3
1.609e-02	-4.13	EF-hand_dom_typ2	interpro domains	IPR015154	6	1	18521	50	DTNA
1.609e-02	-4.13	GAR_dom_sf	interpro domains	IPR036534	6	1	18521	50	MACF1
1.609e-02	-4.13	RIH_dom	interpro domains	IPR000699	6	1	18521	50	RYR3
1.616e-02	-4.13	bone-femur-other-chondroblastoma	COSMIC cancer mutations	bone-femur-other-chondroblastoma	183	3	16828	49	GPC5,PCDH9,RYR3
1.627e-02	-4.12	protein-containing complex binding	molecular function	GO:0044877	1772	10	18094	48	COL5A3,MACF1,GLI3,PTPRZ1,CTNNA2,ABLIM1,NFIA,SPARCL1,CLU,APOE
1.629e-02	-4.12	MKRN2 (makorin ring finger protein 2)	protein interactions	23609	380	4	19454	50	BMPR1B,FGFR3,GLI3,MACF1
1.633e-02	-4.11	RYK (receptor like tyrosine kinase)	protein interactions	6259	208	3	19454	50	PCDH9,CLU,CTNNA2
1.633e-02	-4.11	BCL2L1 (BCL2 like 1)	protein interactions	598	208	3	19454	50	RYR3,CLU,ABLIM1
1.634e-02	-4.11	system process	biological process	GO:0003008	2015	11	18204	49	DTNA,MEIS2,RYR3,ABLIM1,CTNNA2,AQP4,SLC4A4,SLC1A2,PTPRZ1,APOE,SLC1A3
1.635e-02	-4.11	MIR200A (microRNA 200a)	protein interactions	406983	76	2	19454	50	QKI,MSI2
1.652e-02	-4.10	neuron fate commitment	biological process	GO:0048663	73	2	18204	49	NFIA,GLI3
1.652e-02	-4.10	peptide metabolic process	biological process	GO:0006518	73	2	18204	49	SLC1A2,CPE
1.673e-02	-4.09	axonogenesis	biological process	GO:0007409	366	4	18204	49	GLI3,PTPRZ1,BMPR1B,CTNNA2
1.674e-02	-4.09	EF-hand_3	pfam domains	PF09069	6	1	17795	50	DTNA
1.674e-02	-4.09	EF-hand_2	pfam domains	PF09068	6	1	17795	50	DTNA
1.674e-02	-4.09	RIH_assoc	pfam domains	PF08454	6	1	17795	50	RYR3
1.674e-02	-4.09	Plectin	pfam domains	PF00681	6	1	17795	50	MACF1
1.674e-02	-4.09	SH3_10	pfam domains	PF17902	6	1	17795	50	MACF1
1.674e-02	-4.09	Ins145_P3_rec	pfam domains	PF08709	6	1	17795	50	RYR3
1.674e-02	-4.09	Glypican	pfam domains	PF01153	6	1	17795	50	GPC5
1.674e-02	-4.09	GAS2	pfam domains	PF02187	6	1	17795	50	MACF1
1.674e-02	-4.09	TSP1_spondin	pfam domains	PF19028	6	1	17795	50	SPON1
1.674e-02	-4.09	RYDR_ITPR	pfam domains	PF01365	6	1	17795	50	RYR3
1.675e-02	-4.09	skin-head_neck-malignant_melanoma-superficial_spreading	COSMIC cancer mutations	skin-head_neck-malignant_melanoma-superficial_spreading	923	7	16828	49	GLI3,PREX2,COL5A3,SORBS1,CTNND2,MACF1,ATP13A4
1.675e-02	-4.09	ABI1 (abl interactor 1)	protein interactions	10006	210	3	19454	50	SORBS1,SLC1A3,NHSL1
1.695e-02	-4.08	positive regulation of gliogenesis	biological process	GO:0014015	74	2	18204	49	PTPRZ1,QKI
1.695e-02	-4.08	sterol transport	biological process	GO:0015918	74	2	18204	49	APOE,CLU
1.706e-02	-4.07	intracellular calcium ion homeostasis	biological process	GO:0006874	202	3	18204	49	RYR3,APOE,ATP13A4
1.709e-02	-4.07	human chr4q22.3	chromosome location	human chr4q22.3	9	1	26134	50	BMPR1B
1.710e-02	-4.07	head development	biological process	GO:0060322	774	6	18204	49	NDRG2,SLC1A2,PCDH9,GLI3,MEIS2,CTNNA2
1.715e-02	-4.07	extremity	COSMIC cancer mutations	extremity	1876	11	16828	49	ATP13A4,PITPNC1,CDH20,ACSS1,FBXL7,PREX2,COL5A3,RYR3,PTPRZ1,FGFR3,PCDH9
1.717e-02	-4.06	LRP8 (LDL receptor related protein 8)	protein interactions	7804	78	2	19454	50	CLU,APOE
1.717e-02	-4.06	MIR34C (microRNA 34c)	protein interactions	407042	78	2	19454	50	QKI,MSI2
1.735e-02	-4.05	kidney-carcinoma-collecting_duct_carcinoma	COSMIC cancer mutations	kidney-carcinoma-collecting_duct_carcinoma	6	1	16828	49	FGFR3
1.735e-02	-4.05	skin-in_situ_epithelial_neoplasm-actinic_keratosis	COSMIC cancer mutations	skin-in_situ_epithelial_neoplasm-actinic_keratosis	6	1	16828	49	FGFR3
1.735e-02	-4.05	skin-epidermal_nevus	COSMIC cancer mutations	skin-epidermal_nevus	6	1	16828	49	FGFR3
1.735e-02	-4.05	skin-arm-epidermal_nevus	COSMIC cancer mutations	skin-arm-epidermal_nevus	6	1	16828	49	FGFR3
1.735e-02	-4.05	skin-upper_leg-other-seborrhoeic_keratosis	COSMIC cancer mutations	skin-upper_leg-other-seborrhoeic_keratosis	6	1	16828	49	FGFR3
1.735e-02	-4.05	skin-benign_melanocytic_nevus-lentiginous_nevus	COSMIC cancer mutations	skin-benign_melanocytic_nevus-lentiginous_nevus	6	1	16828	49	FGFR3
1.735e-02	-4.05	skin-adnexal_tumour-trichoblastoma	COSMIC cancer mutations	skin-adnexal_tumour-trichoblastoma	6	1	16828	49	FGFR3
1.735e-02	-4.05	autonomic_ganglia-paraganglioma-benign	COSMIC cancer mutations	autonomic_ganglia-paraganglioma-benign	6	1	16828	49	NHSL1
1.735e-02	-4.05	skin-face-other-seborrhoeic_keratosis	COSMIC cancer mutations	skin-face-other-seborrhoeic_keratosis	6	1	16828	49	FGFR3
1.735e-02	-4.05	collecting_duct_carcinoma	COSMIC cancer mutations	collecting_duct_carcinoma	6	1	16828	49	FGFR3
1.735e-02	-4.05	lentiginous_nevus	COSMIC cancer mutations	lentiginous_nevus	6	1	16828	49	FGFR3
1.735e-02	-4.05	skin-lower_back-other-seborrhoeic_keratosis	COSMIC cancer mutations	skin-lower_back-other-seborrhoeic_keratosis	6	1	16828	49	FGFR3
1.735e-02	-4.05	skin-in_situ_epithelial_neoplasm-Bowen_disease	COSMIC cancer mutations	skin-in_situ_epithelial_neoplasm-Bowen_disease	6	1	16828	49	FGFR3
1.735e-02	-4.05	skin-head_neck-epidermal_nevus	COSMIC cancer mutations	skin-head_neck-epidermal_nevus	6	1	16828	49	FGFR3
1.735e-02	-4.05	skin-trunk-epidermal_nevus	COSMIC cancer mutations	skin-trunk-epidermal_nevus	6	1	16828	49	FGFR3
1.735e-02	-4.05	skin-forearm-malignant_melanoma-superficial_spreading	COSMIC cancer mutations	skin-forearm-malignant_melanoma-superficial_spreading	6	1	16828	49	PREX2
1.735e-02	-4.05	skin-abdomen-other-seborrhoeic_keratosis	COSMIC cancer mutations	skin-abdomen-other-seborrhoeic_keratosis	6	1	16828	49	FGFR3
1.735e-02	-4.05	skin-back-other-seborrhoeic_keratosis	COSMIC cancer mutations	skin-back-other-seborrhoeic_keratosis	6	1	16828	49	FGFR3
1.735e-02	-4.05	skin-flank-other-seborrhoeic_keratosis	COSMIC cancer mutations	skin-flank-other-seborrhoeic_keratosis	6	1	16828	49	FGFR3
1.735e-02	-4.05	skin-head_neck-malignant_melanoma	COSMIC cancer mutations	skin-head_neck-malignant_melanoma	6	1	16828	49	PREX2
1.735e-02	-4.05	skin-lower_leg-epidermal_nevus	COSMIC cancer mutations	skin-lower_leg-epidermal_nevus	6	1	16828	49	FGFR3
1.738e-02	-4.05	regulation of behavior	biological process	GO:0050795	75	2	18204	49	PTGDS,APOE
1.744e-02	-4.05	Bile Acid Indirect Signalling Pathway	SMPDB pathways	SMP0086851	8	1	1369	3	FGFR3
1.759e-02	-4.04	PRDM1 (PR/SET domain 1)	protein interactions	639	79	2	19454	50	NFIA,TRPS1
1.782e-02	-4.03	regulation of axon extension	biological process	GO:0030516	76	2	18204	49	APOE,MACF1
1.783e-02	-4.03	Ectoderm Differentiation	WikiPathways	WP2858	143	3	5310	21	CTNND2,GLI3,CTNNA2
1.785e-02	-4.03	nitrogen compound transport	biological process	GO:0071705	1507	9	18204	49	MACF1,APOE,SLC1A3,GLI3,ATP13A4,CPE,SLC1A2,QKI,CLU
1.786e-02	-4.03	Fbxo3 (F-box protein 3)	protein interactions	57443	7	1	19454	50	BMPR1B
1.786e-02	-4.03	SLC16A5 (solute carrier family 16 member 5)	protein interactions	9121	7	1	19454	50	PTPRZ1
1.786e-02	-4.03	RGMB (repulsive guidance molecule BMP co-receptor b)	protein interactions	285704	7	1	19454	50	BMPR1B
1.786e-02	-4.03	Smurf1 (SMAD specific E3 ubiquitin protein ligase 1)	protein interactions	75788	7	1	19454	50	GLIS3
1.786e-02	-4.03	Smad7 (SMAD family member 7)	protein interactions	17131	7	1	19454	50	BMPR1B
1.786e-02	-4.03	C8B (complement C8 beta chain)	protein interactions	732	7	1	19454	50	CLU
1.786e-02	-4.03	SOAT2 (sterol O-acyltransferase 2)	protein interactions	8435	7	1	19454	50	CLU
1.786e-02	-4.03	Pum2 (pumilio RNA-binding family member 2)	protein interactions	80913	7	1	19454	50	QKI
1.786e-02	-4.03	ZNF701 (zinc finger protein 701)	protein interactions	55762	7	1	19454	50	ARHGAP24
1.786e-02	-4.03	CYP4F8 (cytochrome P450 family 4 subfamily F member 8)	protein interactions	11283	7	1	19454	50	CLU
1.786e-02	-4.03	ZNF501 (zinc finger protein 501)	protein interactions	115560	7	1	19454	50	ARHGAP24
1.786e-02	-4.03	C7 (complement C7)	protein interactions	730	7	1	19454	50	CLU
1.786e-02	-4.03	FGF5 (fibroblast growth factor 5)	protein interactions	2250	7	1	19454	50	FGFR3
1.786e-02	-4.03	ABCC12 (ATP binding cassette subfamily C member 12)	protein interactions	94160	7	1	19454	50	NPAS3
1.786e-02	-4.03	Uhmk1 (U2AF homology motif (UHM) kinase 1)	protein interactions	16589	7	1	19454	50	BMPR1B
1.786e-02	-4.03	SASH3 (SAM and SH3 domain containing 3)	protein interactions	54440	7	1	19454	50	BMPR1B
1.801e-02	-4.02	MAP2 (microtubule associated protein 2)	protein interactions	4133	80	2	19454	50	GPM6A,APOE
1.811e-02	-4.01	Plakin repeat	gene3d domains	3.90.1290.10	6	1	14470	44	MACF1
1.811e-02	-4.01	Gas2-like domain	gene3d domains	3.30.920.20	6	1	14470	44	MACF1
1.811e-02	-4.01	IP3 receptor type 1 binding core, RIH domain	gene3d domains	1.25.10.30	6	1	14470	44	RYR3
1.827e-02	-4.00	BMP signaling pathway	biological process	GO:0030509	77	2	18204	49	NFIA,BMPR1B
1.837e-02	-4.00	oesophagus-middle_third-carcinoma-squamous_cell_carcinoma	COSMIC cancer mutations	oesophagus-middle_third-carcinoma-squamous_cell_carcinoma	3531	17	16828	49	GPM6A,RYR3,CTNND2,PREX2,GPC5,SPARCL1,SLC4A4,NHSL1,PAMR1,COL5A3,SPON1,PCDH9,PTPRZ1,ABLIM1,MAML2,MACF1,PON2
1.840e-02	-4.00	actin filament binding	molecular function	GO:0051015	211	3	18094	48	CTNNA2,MACF1,ABLIM1
1.843e-02	-3.99	LBD domain binding	molecular function	GO:0050693	7	1	18094	48	SPON1
1.843e-02	-3.99	phosphatidic acid transfer activity	molecular function	GO:1990050	7	1	18094	48	PITPNC1
1.843e-02	-3.99	SOX17 (SRY-box transcription factor 17)	protein interactions	64321	81	2	19454	50	NFIA,TRPS1
1.843e-02	-3.99	ARNT2 (aryl hydrocarbon receptor nuclear translocator 2)	protein interactions	9915	81	2	19454	50	NPAS3,MEIS2
1.844e-02	-3.99	regulation of neurogenesis	biological process	GO:0050767	377	4	18204	49	GLI3,QKI,PTPRZ1,MACF1
1.847e-02	-3.99	middle_third	COSMIC cancer mutations	middle_third	3533	17	16828	49	COL5A3,PTPRZ1,SPON1,PCDH9,PON2,MAML2,MACF1,ABLIM1,PREX2,CTNND2,RYR3,GPM6A,SPARCL1,GPC5,SLC4A4,PAMR1,NHSL1
1.869e-02	-3.98	glial cell fate specification	biological process	GO:0021780	7	1	18204	49	NFIA
1.869e-02	-3.98	cellular response to magnesium ion	biological process	GO:0071286	7	1	18204	49	RYR3
1.869e-02	-3.98	cell fate specification involved in pattern specification	biological process	GO:0060573	7	1	18204	49	GLI3
1.869e-02	-3.98	chaperone-mediated autophagy	biological process	GO:0061684	7	1	18204	49	CLU
1.869e-02	-3.98	ventral spinal cord interneuron specification	biological process	GO:0021521	7	1	18204	49	GLI3
1.869e-02	-3.98	forebrain dorsal/ventral pattern formation	biological process	GO:0021798	7	1	18204	49	GLI3
1.869e-02	-3.98	regulation of male germ cell proliferation	biological process	GO:2000254	7	1	18204	49	PTGDS
1.869e-02	-3.98	regulation of 3'-UTR-mediated mRNA stabilization	biological process	GO:1905868	7	1	18204	49	QKI
1.869e-02	-3.98	regulation of cardiac muscle myoblast proliferation	biological process	GO:0110022	7	1	18204	49	MEIS2
1.869e-02	-3.98	regulation of oligodendrocyte progenitor proliferation	biological process	GO:0070445	7	1	18204	49	PTPRZ1
1.869e-02	-3.98	negative regulation of ruffle assembly	biological process	GO:1900028	7	1	18204	49	ARHGAP24
1.869e-02	-3.98	forebrain radial glial cell differentiation	biological process	GO:0021861	7	1	18204	49	GLI3
1.869e-02	-3.98	high-density lipoprotein particle clearance	biological process	GO:0034384	7	1	18204	49	APOE
1.869e-02	-3.98	negative regulation of Arp2/3 complex-mediated actin nucleation	biological process	GO:0034316	7	1	18204	49	CTNNA2
1.869e-02	-3.98	positive regulation of receptor catabolic process	biological process	GO:2000646	7	1	18204	49	APOE
1.869e-02	-3.98	positive regulation of transcription of Notch receptor target	biological process	GO:0007221	7	1	18204	49	MAML2
1.869e-02	-3.98	very-low-density lipoprotein particle remodeling	biological process	GO:0034372	7	1	18204	49	APOE
1.869e-02	-3.98	hindgut morphogenesis	biological process	GO:0007442	7	1	18204	49	GLI3
1.872e-02	-3.98	positive regulation of carbohydrate metabolic process	biological process	GO:0045913	78	2	18204	49	SLC4A4,SORBS1
1.872e-02	-3.98	regulation of glucose transmembrane transport	biological process	GO:0010827	78	2	18204	49	SLC1A2,SORBS1
1.872e-02	-3.98	dicarboxylic acid transport	biological process	GO:0006835	78	2	18204	49	SLC1A3,SLC1A2
1.872e-02	-3.98	positive regulation of osteoblast differentiation	biological process	GO:0045669	78	2	18204	49	BMPR1B,GLI3
1.875e-02	-3.98	Plakophilin/d_Catenin	interpro domains	IPR028435	7	1	18521	50	CTNND2
1.875e-02	-3.98	SPARC/Testican_Ca-bd-dom	interpro domains	IPR019577	7	1	18521	50	SPARCL1
1.875e-02	-3.98	Aquaporin_transptr	interpro domains	IPR034294	7	1	18521	50	AQP4
1.875e-02	-3.98	Plakin_repeat_sf	interpro domains	IPR035915	7	1	18521	50	MACF1
1.875e-02	-3.98	Alpha-catenin/vinculin-like_sf	interpro domains	IPR036723	7	1	18521	50	CTNNA2
1.875e-02	-3.98	Plectin_repeat	interpro domains	IPR001101	7	1	18521	50	MACF1
1.875e-02	-3.98	GS_dom	interpro domains	IPR003605	7	1	18521	50	BMPR1B
1.886e-02	-3.97	GSC (goosecoid homeobox)	protein interactions	145258	82	2	19454	50	TRPS1,NFIA
1.897e-02	-3.96	human chr9p24.2	chromosome location	human chr9p24.2	10	1	26134	50	GLIS3
1.899e-02	-3.96	PITRANSFER	prints domains	PR00391	5	1	5227	20	PITPNC1
1.899e-02	-3.96	NAHCO3TRSPRT	prints domains	PR01232	5	1	5227	20	SLC4A4
1.914e-02	-3.96	central_nervous_system-brain-glioma-oligodendroglioma_Grade_II	COSMIC cancer mutations	central_nervous_system-brain-glioma-oligodendroglioma_Grade_II	73	2	16828	49	FGFR3,MACF1
1.917e-02	-3.95	regulation of glial cell differentiation	biological process	GO:0045685	79	2	18204	49	PTPRZ1,QKI
1.922e-02	-3.95	prostate	COSMIC cancer mutations	prostate	13883	46	16828	49	SPARCL1,LSAMP,RYR3,SLC1A2,CPE,AQP4,BMPR1B,NFIA,TRPS1,GPM6A,SORBS1,NHSL1,MSI2,PAMR1,COL5A3,FBXL7,ACSS1,MAML2,CLU,ABLIM1,GPC5,CTNND2,NTM,MEIS2,NPAS3,ATP13A4,QKI,SLC4A4,NDRG2,PTPRZ1,SPON1,SLC1A3,GLIS3,PITPNC1,MACF1,PARD3B,PREX2,ARHGAP24,CDH20,FGFR3,GLI3,PCDH9,NKAIN3,APOE,PON2,DTNA
1.930e-02	-3.95	PAX2 (paired box 2)	protein interactions	5076	83	2	19454	50	TRPS1,NFIA
1.930e-02	-3.95	DNM3 (dynamin 3)	protein interactions	26052	83	2	19454	50	GPM6A,FGFR3
1.930e-02	-3.95	TM2D3 (TM2 domain containing 3)	protein interactions	80213	83	2	19454	50	PON2,FGFR3
1.939e-02	-3.94	PSEN1 (presenilin 1)	protein interactions	5663	222	3	19454	50	CTNND2,DTNA,APOE
1.944e-02	-3.94	inorganic cation transmembrane transporter activity	molecular function	GO:0022890	589	5	18094	48	RYR3,SLC1A2,SLC1A3,SLC4A4,GPM6A
1.951e-02	-3.94	Oncogenic MAPK signaling	REACTOME pathways	R-HSA-6802957	74	2	10285	30	QKI,MACF1
1.951e-02	-3.94	SPARC_Ca_bdg	pfam domains	PF10591	7	1	17795	50	SPARCL1
1.951e-02	-3.94	TGF_beta_GS	pfam domains	PF08515	7	1	17795	50	BMPR1B
1.954e-02	-3.94	transmembrane receptor protein kinase activity	molecular function	GO:0019199	81	2	18094	48	FGFR3,BMPR1B
1.955e-02	-3.93	sensory organ development	biological process	GO:0007423	581	5	18204	49	MEIS2,GPM6A,BMPR1B,NFIA,GLI3
1.964e-02	-3.93	oligodendroglioma_Grade_II	COSMIC cancer mutations	oligodendroglioma_Grade_II	74	2	16828	49	MACF1,FGFR3
1.970e-02	-3.93	Bile secretion	KEGG pathways	ko04976	71	2	7161	22	AQP4,SLC4A4
1.970e-02	-3.93	Bile secretion	KEGG pathways	hsa04976	71	2	7161	22	SLC4A4,AQP4
1.977e-02	-3.92	chondrosarcoma	COSMIC cancer mutations	chondrosarcoma	1181	8	16828	49	LSAMP,COL5A3,SPON1,NDRG2,PARD3B,SLC4A4,CPE,PON2
1.985e-02	-3.92	MAPRE3 (microtubule associated protein RP/EB family member 3)	protein interactions	22924	224	3	19454	50	MACF1,ABLIM1,GPM6A
1.991e-02	-3.92	FGFR1 (fibroblast growth factor receptor 1)	protein interactions	2260	611	5	19454	50	ABLIM1,CLU,FGFR3,DTNA,NHSL1
2.004e-02	-3.91	somatodendritic compartment	cellular component	GO:0036477	842	6	19108	49	CTNND2,BMPR1B,GPM6A,APOE,SLC1A3,CLU
2.018e-02	-3.90	CCND3 (cyclin D3)	protein interactions	896	85	2	19454	50	CLU,QKI
2.021e-02	-3.90	skin-shoulder-other-seborrhoeic_keratosis	COSMIC cancer mutations	skin-shoulder-other-seborrhoeic_keratosis	7	1	16828	49	FGFR3
2.021e-02	-3.90	urinary_tract-carcinoma-transitional_cell_carcinoma	COSMIC cancer mutations	urinary_tract-carcinoma-transitional_cell_carcinoma	7	1	16828	49	FGFR3
2.021e-02	-3.90	skin-adnexal_tumour-trichilemmoma	COSMIC cancer mutations	skin-adnexal_tumour-trichilemmoma	7	1	16828	49	FGFR3
2.021e-02	-3.90	skin-face-adnexal_tumour-malignant_adnexal_tumour	COSMIC cancer mutations	skin-face-adnexal_tumour-malignant_adnexal_tumour	7	1	16828	49	FGFR3
2.021e-02	-3.90	skin-chest-other-seborrhoeic_keratosis	COSMIC cancer mutations	skin-chest-other-seborrhoeic_keratosis	7	1	16828	49	FGFR3
2.021e-02	-3.90	skin-neck-other-seborrhoeic_keratosis	COSMIC cancer mutations	skin-neck-other-seborrhoeic_keratosis	7	1	16828	49	FGFR3
2.021e-02	-3.90	skin-upper_leg-malignant_melanoma-nodular	COSMIC cancer mutations	skin-upper_leg-malignant_melanoma-nodular	7	1	16828	49	PREX2
2.021e-02	-3.90	skin-benign_melanocytic_nevus-intradermal	COSMIC cancer mutations	skin-benign_melanocytic_nevus-intradermal	7	1	16828	49	FGFR3
2.021e-02	-3.90	skin-face-malignant_melanoma-nodular	COSMIC cancer mutations	skin-face-malignant_melanoma-nodular	7	1	16828	49	PREX2
2.021e-02	-3.90	nevus_sebaceous	COSMIC cancer mutations	nevus_sebaceous	7	1	16828	49	FGFR3
2.021e-02	-3.90	skin-other-nevus_sebaceous	COSMIC cancer mutations	skin-other-nevus_sebaceous	7	1	16828	49	FGFR3
2.021e-02	-3.90	trichilemmoma	COSMIC cancer mutations	trichilemmoma	7	1	16828	49	FGFR3
2.021e-02	-3.90	skin-benign_melanocytic_nevus-compound	COSMIC cancer mutations	skin-benign_melanocytic_nevus-compound	7	1	16828	49	FGFR3
2.023e-02	-3.90	Adherens junction	KEGG pathways	hsa04520	72	2	7161	22	CTNNA2,SORBS1
2.023e-02	-3.90	Adherens junction	KEGG pathways	ko04520	72	2	7161	22	SORBS1,CTNNA2
2.023e-02	-3.90	monoatomic ion transmembrane transport	biological process	GO:0034220	804	6	18204	49	GPM6A,RYR3,SLC1A2,SLC1A3,SLC4A4,ATP13A4
2.025e-02	-3.90	FGFR3b ligand binding and activation	REACTOME pathways	R-HSA-190371	7	1	10285	30	FGFR3
2.034e-02	-3.90	HFE-transferrin receptor complex	cellular component	GO:1990712	8	1	19108	49	BMPR1B
2.034e-02	-3.90	spherical high-density lipoprotein particle	cellular component	GO:0034366	8	1	19108	49	CLU
2.034e-02	-3.90	zonula adherens	cellular component	GO:0005915	8	1	19108	49	SORBS1
2.038e-02	-3.89	Chmp2a (charged multivesicular body protein 2A)	protein interactions	68953	8	1	19454	50	CLU
2.038e-02	-3.89	Rps27a (ribosomal protein S27A)	protein interactions	78294	8	1	19454	50	BMPR1B
2.038e-02	-3.89	Rasd2 (RASD family, member 2)	protein interactions	75141	8	1	19454	50	BMPR1B
2.038e-02	-3.89	INSM1 (INSM transcriptional repressor 1)	protein interactions	3642	8	1	19454	50	SORBS1
2.038e-02	-3.89	Setdb1 (SET domain, bifurcated 1)	protein interactions	84505	8	1	19454	50	AMZ2
2.038e-02	-3.89	BMP15 (bone morphogenetic protein 15)	protein interactions	9210	8	1	19454	50	BMPR1B
2.038e-02	-3.89	SCT (secretin)	protein interactions	6343	8	1	19454	50	MEIS2
2.038e-02	-3.89	LHB (luteinizing hormone subunit beta)	protein interactions	3972	8	1	19454	50	NTM
2.038e-02	-3.89	ZNF236 (zinc finger protein 236)	protein interactions	7776	8	1	19454	50	ARHGAP24
2.038e-02	-3.89	PTGER1 (prostaglandin E receptor 1)	protein interactions	5731	8	1	19454	50	PTGDS
2.038e-02	-3.89	CCK (cholecystokinin)	protein interactions	885	8	1	19454	50	CPE
2.038e-02	-3.89	ZNF28 (zinc finger protein 28)	protein interactions	7576	8	1	19454	50	ARHGAP24
2.038e-02	-3.89	DEPP1 (DEPP autophagy regulator 1)	protein interactions	11067	8	1	19454	50	QKI
2.038e-02	-3.89	ZNF568 (zinc finger protein 568)	protein interactions	374900	8	1	19454	50	ARHGAP24
2.051e-02	-3.89	GLYPICAN	prosite domains	PS01207	6	1	12186	42	GPC5
2.051e-02	-3.89	GAR	prosite domains	PS51460	6	1	12186	42	MACF1
2.053e-02	-3.89	contractile actin filament bundle	cellular component	GO:0097517	86	2	19108	49	ABLIM1,SORBS1
2.053e-02	-3.89	stress fiber	cellular component	GO:0001725	86	2	19108	49	SORBS1,ABLIM1
2.063e-02	-3.88	SYNJ1 (synaptojanin 1)	protein interactions	8867	86	2	19454	50	SORBS1,GPM6A
2.084e-02	-3.87	dendrite	cellular component	GO:0030425	620	5	19108	49	CTNND2,BMPR1B,CLU,GPM6A,APOE
2.101e-02	-3.86	EF_hand_dom	interpro domains	IPR002048	218	3	18521	50	RYR3,MACF1,SPARCL1
2.103e-02	-3.86	BMP receptor activity	molecular function	GO:0098821	8	1	18094	48	BMPR1B
2.103e-02	-3.86	glutamate binding	molecular function	GO:0016595	8	1	18094	48	SLC1A3
2.105e-02	-3.86	glutamatergic synapse	cellular component	GO:0098978	412	4	19108	49	SPARCL1,SLC1A2,GPM6A,APOE
2.108e-02	-3.86	MIR141 (microRNA 141)	protein interactions	406933	87	2	19454	50	QKI,MSI2
2.108e-02	-3.86	Kctd5 (potassium channel tetramerisation domain containing 5)	protein interactions	69259	87	2	19454	50	TRPS1,SLC1A3
2.108e-02	-3.86	NHLH1 (nescient helix-loop-helix 1)	protein interactions	4807	87	2	19454	50	TRPS1,NFIA
2.110e-02	-3.86	dendritic tree	cellular component	GO:0097447	622	5	19108	49	CTNND2,BMPR1B,CLU,APOE,GPM6A
2.123e-02	-3.85	clear_cell_renal_cell_carcinoma	COSMIC cancer mutations	clear_cell_renal_cell_carcinoma	13924	46	16828	49	DTNA,APOE,GLI3,FGFR3,NKAIN3,AMZ2,PCDH9,ARHGAP24,CDH20,PREX2,PARD3B,MACF1,PITPNC1,GLIS3,PTPRZ1,NDRG2,SLC1A3,SPON1,NPAS3,MEIS2,SLC4A4,QKI,ATP13A4,CTNND2,GPC5,MAML2,CLU,ABLIM1,FBXL7,ACSS1,COL5A3,PTGDS,MSI2,PAMR1,NHSL1,SORBS1,GPM6A,TRPS1,NFIA,BMPR1B,AQP4,CPE,LSAMP,SLC1A2,RYR3,SPARCL1
2.123e-02	-3.85	kidney-carcinoma-clear_cell_renal_cell_carcinoma	COSMIC cancer mutations	kidney-carcinoma-clear_cell_renal_cell_carcinoma	13924	46	16828	49	FBXL7,ACSS1,COL5A3,AMZ2,NKAIN3,PCDH9,FGFR3,GLI3,DTNA,ABLIM1,CLU,MAML2,APOE,SORBS1,GPM6A,PREX2,TRPS1,NFIA,PARD3B,PTGDS,MSI2,PAMR1,CDH20,NHSL1,ARHGAP24,BMPR1B,GLIS3,SLC1A3,SPON1,NDRG2,PTPRZ1,MACF1,PITPNC1,CTNND2,SLC1A2,RYR3,LSAMP,SPARCL1,GPC5,SLC4A4,ATP13A4,CPE,AQP4,QKI,MEIS2,NPAS3
2.126e-02	-3.85	femur	COSMIC cancer mutations	femur	1197	8	16828	49	RYR3,PTPRZ1,GLI3,PCDH9,GPC5,SPON1,PON2,SLC4A4
2.134e-02	-3.85	regulation of Cdc42 protein signal transduction	biological process	GO:0032489	8	1	18204	49	APOE
2.134e-02	-3.85	insulin processing	biological process	GO:0030070	8	1	18204	49	CPE
2.134e-02	-3.85	regulation of germ cell proliferation	biological process	GO:1905936	8	1	18204	49	PTGDS
2.134e-02	-3.85	triglyceride-rich lipoprotein particle remodeling	biological process	GO:0034370	8	1	18204	49	APOE
2.134e-02	-3.85	hindgut development	biological process	GO:0061525	8	1	18204	49	GLI3
2.134e-02	-3.85	gamma-aminobutyric acid metabolic process	biological process	GO:0009448	8	1	18204	49	SLC1A3
2.134e-02	-3.85	positive regulation of CoA-transferase activity	biological process	GO:1905920	8	1	18204	49	APOE
2.134e-02	-3.85	regulation of synapse structural plasticity	biological process	GO:0051823	8	1	18204	49	CTNNA2
2.134e-02	-3.85	positive regulation of amyloid-beta clearance	biological process	GO:1900223	8	1	18204	49	APOE
2.134e-02	-3.85	smooth muscle cell proliferation	biological process	GO:0048659	8	1	18204	49	NDRG2
2.137e-02	-3.85	Diseases of signal transduction	REACTOME pathways	R-HSA-5663202	369	4	10285	30	MAML2,FGFR3,QKI,MACF1
2.140e-02	-3.84	Villin_headpiece_dom_sf	interpro domains	IPR036886	8	1	18521	50	ABLIM1
2.140e-02	-3.84	Villin_headpiece	interpro domains	IPR003128	8	1	18521	50	ABLIM1
2.140e-02	-3.84	Plakin	interpro domains	IPR043197	8	1	18521	50	MACF1
2.142e-02	-3.84	GAS2	smart domains	SM00243	6	1	9717	35	MACF1
2.151e-02	-3.84	L-amino acid transport	biological process	GO:0015807	84	2	18204	49	SLC1A2,SLC1A3
2.153e-02	-3.84	HSPG2 (heparan sulfate proteoglycan 2)	protein interactions	3339	88	2	19454	50	GLI3,GPC5
2.175e-02	-3.83	CTSB (cathepsin B)	protein interactions	1508	232	3	19454	50	MSI2,CST3,APOE
2.199e-02	-3.82	SOX10 (SRY-box transcription factor 10)	protein interactions	6663	89	2	19454	50	NFIA,TRPS1
2.201e-02	-3.82	organic anion transport	biological process	GO:0015711	398	4	18204	49	SLC4A4,SLC1A2,APOE,SLC1A3
2.226e-02	-3.80	VHP	pfam domains	PF02209	8	1	17795	50	ABLIM1
2.229e-02	-3.80	cell-cell signaling	biological process	GO:0007267	822	6	18204	49	SLC1A2,APOE,SLC1A3,DTNA,FGFR3,CPE
2.232e-02	-3.80	lung-left_upper_lobe-carcinoma-adenocarcinoma	COSMIC cancer mutations	lung-left_upper_lobe-carcinoma-adenocarcinoma	556	5	16828	49	CTNND2,SLC4A4,RYR3,FBXL7,TRPS1
2.247e-02	-3.80	Golgi apparatus	cellular component	GO:0005794	1645	9	19108	49	CPE,PTGDS,FGFR3,APOE,GPC5,MACF1,NDRG2,CST3,CLU
2.262e-02	-3.79	left_upper_lobe	COSMIC cancer mutations	left_upper_lobe	558	5	16828	49	TRPS1,CTNND2,SLC4A4,RYR3,FBXL7
2.272e-02	-3.78	human chr11p15.2	chromosome location	human chr11p15.2	12	1	26134	50	SPON1
2.272e-02	-3.78	human chr6q26	chromosome location	human chr6q26	12	1	26134	50	QKI
2.274e-02	-3.78	CTSL (cathepsin L)	protein interactions	1514	236	3	19454	50	CST3,CLU,PON2
2.275e-02	-3.78	ACTIVIN2R	prints domains	PR00653	6	1	5227	20	BMPR1B
2.285e-02	-3.78	astrocyte end-foot	cellular component	GO:0097450	9	1	19108	49	AQP4
2.285e-02	-3.78	flotillin complex	cellular component	GO:0016600	9	1	19108	49	SORBS1
2.290e-02	-3.78	CACNA2D3 (calcium voltage-gated channel auxiliary subunit alpha2delta 3)	protein interactions	55799	9	1	19454	50	APOE
2.290e-02	-3.78	LINC02582 (long intergenic non-protein coding RNA 2582)	protein interactions	100505817	9	1	19454	50	APOE
2.290e-02	-3.78	GUSBP1 (GUSB pseudogene 1)	protein interactions	728411	9	1	19454	50	FGFR3
2.290e-02	-3.78	Ywhag (tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide)	protein interactions	22628	9	1	19454	50	QKI
2.290e-02	-3.78	ZNF766 (zinc finger protein 766)	protein interactions	90321	9	1	19454	50	ARHGAP24
2.290e-02	-3.78	Tyw3 (tRNA-yW synthesizing protein 3 homolog (S. cerevisiae))	protein interactions	209584	9	1	19454	50	CTNNA2
2.290e-02	-3.78	VEPH1 (ventricular zone expressed PH domain containing 1)	protein interactions	79674	9	1	19454	50	BMPR1B
2.290e-02	-3.78	KCNV2 (potassium voltage-gated channel modifier subfamily V member 2)	protein interactions	169522	9	1	19454	50	AMZ2
2.290e-02	-3.78	NRXN2 (neurexin 2)	protein interactions	9379	9	1	19454	50	MACF1
2.292e-02	-3.78	DGUOK (deoxyguanosine kinase)	protein interactions	1716	91	2	19454	50	GPM6A,NTM
2.292e-02	-3.78	FOXI1 (forkhead box I1)	protein interactions	2299	91	2	19454	50	NFIA,TRPS1
2.296e-02	-3.77	dorsal/ventral pattern formation	biological process	GO:0009953	87	2	18204	49	GLI3,BMPR1B
2.306e-02	-3.77	trichoblastoma	COSMIC cancer mutations	trichoblastoma	8	1	16828	49	FGFR3
2.306e-02	-3.77	cervical_intraepithelial_neoplasia_Grade_I	COSMIC cancer mutations	cervical_intraepithelial_neoplasia_Grade_I	8	1	16828	49	FGFR3
2.306e-02	-3.77	central_nervous_system-chiasm-glioma-astrocytoma_Grade_I	COSMIC cancer mutations	central_nervous_system-chiasm-glioma-astrocytoma_Grade_I	8	1	16828	49	QKI
2.306e-02	-3.77	skin-chest-malignant_melanoma-nodular	COSMIC cancer mutations	skin-chest-malignant_melanoma-nodular	8	1	16828	49	PREX2
2.306e-02	-3.77	actinic_keratosis	COSMIC cancer mutations	actinic_keratosis	8	1	16828	49	FGFR3
2.306e-02	-3.77	cervix-in_situ_neoplasm-cervical_intraepithelial_neoplasia_Grade_I	COSMIC cancer mutations	cervix-in_situ_neoplasm-cervical_intraepithelial_neoplasia_Grade_I	8	1	16828	49	FGFR3
2.306e-02	-3.77	junctional	COSMIC cancer mutations	junctional	8	1	16828	49	FGFR3
2.306e-02	-3.77	urinary_tract-ureter-carcinoma-transitional_cell_carcinoma	COSMIC cancer mutations	urinary_tract-ureter-carcinoma-transitional_cell_carcinoma	8	1	16828	49	FGFR3
2.311e-02	-3.77	Release of Hh-Np from the secreting cell	REACTOME pathways	R-HSA-5362798	8	1	10285	30	GPC5
2.324e-02	-3.76	LCOR (ligand dependent nuclear receptor corepressor)	protein interactions	84458	238	3	19454	50	SPARCL1,MACF1,CLU
2.325e-02	-3.76	forearm	COSMIC cancer mutations	forearm	81	2	16828	49	PREX2,FGFR3
2.329e-02	-3.76	actomyosin	cellular component	GO:0042641	92	2	19108	49	ABLIM1,SORBS1
2.330e-02	-3.76	RNF43 (ring finger protein 43)	protein interactions	54894	424	4	19454	50	QKI,MACF1,ABLIM1,GLI3
2.339e-02	-3.76	RLN1 (relaxin 1)	protein interactions	6013	92	2	19454	50	PON2,CPE
2.339e-02	-3.76	POTEI (POTE ankyrin domain family member I)	protein interactions	653269	92	2	19454	50	FGFR3,DTNA
2.339e-02	-3.76	SOX9 (SRY-box transcription factor 9)	protein interactions	6662	92	2	19454	50	TRPS1,NFIA
2.341e-02	-3.75	skeletal system morphogenesis	biological process	GO:0048705	228	3	18204	49	BMPR1B,FGFR3,GLI3
2.350e-02	-3.75	Validated targets of C-MYC transcriptional repression	Pathway Interaction DB	myc_represspathway	61	2	2226	9	NDRG2,CLU
2.387e-02	-3.74	MIR19B2 (microRNA 19b-2)	protein interactions	406981	93	2	19454	50	MSI2,QKI
2.387e-02	-3.74	ARHGEF6 (Rac/Cdc42 guanine nucleotide exchange factor 6)	protein interactions	9459	93	2	19454	50	ABLIM1,BMPR1B
2.387e-02	-3.74	DMRTB1 (DMRT like family B with proline rich C-terminal 1)	protein interactions	63948	93	2	19454	50	QKI,MSI2
2.388e-02	-3.73	GS	prosite domains	PS51256	7	1	12186	42	BMPR1B
2.395e-02	-3.73	positive regulation of lipid biosynthetic process	biological process	GO:0046889	89	2	18204	49	SORBS1,APOE
2.395e-02	-3.73	cell fate specification	biological process	GO:0001708	89	2	18204	49	GLI3,NFIA
2.397e-02	-3.73	microglial cell proliferation	biological process	GO:0061518	9	1	18204	49	CLU
2.397e-02	-3.73	cranial suture morphogenesis	biological process	GO:0060363	9	1	18204	49	GLI3
2.397e-02	-3.73	sterol catabolic process	biological process	GO:0016127	9	1	18204	49	APOE
2.397e-02	-3.73	macrophage proliferation	biological process	GO:0061517	9	1	18204	49	CLU
2.397e-02	-3.73	embryonic neurocranium morphogenesis	biological process	GO:0048702	9	1	18204	49	GLI3
2.397e-02	-3.73	release of sequestered calcium ion into cytosol by sarcoplasmic reticulum	biological process	GO:0014808	9	1	18204	49	RYR3
2.397e-02	-3.73	negative regulation of actin nucleation	biological process	GO:0051126	9	1	18204	49	CTNNA2
2.397e-02	-3.73	cholesterol catabolic process	biological process	GO:0006707	9	1	18204	49	APOE
2.397e-02	-3.73	cyclooxygenase pathway	biological process	GO:0019371	9	1	18204	49	PTGDS
2.397e-02	-3.73	hindbrain radial glia guided cell migration	biological process	GO:0021932	9	1	18204	49	CTNNA2
2.397e-02	-3.73	polyamine transmembrane transport	biological process	GO:1902047	9	1	18204	49	ATP13A4
2.397e-02	-3.73	semicircular canal development	biological process	GO:0060872	9	1	18204	49	GLI3
2.404e-02	-3.73	Activin_recp	interpro domains	IPR000472	9	1	18521	50	BMPR1B
2.404e-02	-3.73	Band3_cytoplasmic_dom	interpro domains	IPR013769	9	1	18521	50	SLC4A4
2.404e-02	-3.73	Prot_inh_cystat_CS	interpro domains	IPR018073	9	1	18521	50	CST3
2.404e-02	-3.73	Fol_N	interpro domains	IPR003645	9	1	18521	50	SPARCL1
2.407e-02	-3.73	Villin headpiece domain	gene3d domains	1.10.950.10	8	1	14470	44	ABLIM1
2.408e-02	-3.73	ion binding	molecular function	GO:0043167	6007	23	18094	48	DTNA,TRPS1,PITPNC1,APOE,PAMR1,ABLIM1,CPE,ACSS1,FGFR3,PCDH9,GLIS3,SLC1A2,AMZ2,RYR3,PON2,PTGDS,SLC1A3,SPARCL1,ATP13A4,MACF1,GLI3,BMPR1B,SPON1
2.422e-02	-3.72	calcium ion homeostasis	biological process	GO:0055074	231	3	18204	49	ATP13A4,RYR3,APOE
2.430e-02	-3.72	protein binding	molecular function	GO:0005515	13983	43	18094	48	PITPNC1,AQP4,APOE,NFIA,TRPS1,DTNA,SORBS1,FGFR3,CTNND2,QKI,NDRG2,SLC1A3,CDH20,CLU,NTM,RYR3,PON2,MEIS2,BMPR1B,MACF1,LSAMP,FBXL7,NPAS3,COL5A3,CPE,ACSS1,ABLIM1,SLC1A2,GLIS3,PTGDS,SPARCL1,PTPRZ1,ARHGAP24,PARD3B,GLI3,CST3,SLC4A4,SPON1,MAML2,MSI2,CTNNA2,GPM6A,GPC5
2.435e-02	-3.72	TTR (transthyretin)	protein interactions	7276	94	2	19454	50	CTNND2,CLU
2.459e-02	-3.71	human chr5p15.1	chromosome location	human chr5p15.1	13	1	26134	50	FBXL7
2.483e-02	-3.70	H2BC13 (H2B clustered histone 13)	protein interactions	8340	95	2	19454	50	ARHGAP24,GPM6A
2.495e-02	-3.69	PLEC	smart domains	SM00250	7	1	9717	35	MACF1
2.495e-02	-3.69	GS	smart domains	SM00467	7	1	9717	35	BMPR1B
2.496e-02	-3.69	response to BMP	biological process	GO:0071772	91	2	18204	49	BMPR1B,NFIA
2.496e-02	-3.69	cellular response to BMP stimulus	biological process	GO:0071773	91	2	18204	49	BMPR1B,NFIA
2.501e-02	-3.69	Band_3_cyto	pfam domains	PF07565	9	1	17795	50	SLC4A4
2.501e-02	-3.69	Activin_recp	pfam domains	PF01064	9	1	17795	50	BMPR1B
2.519e-02	-3.68	chemical synaptic transmission	biological process	GO:0007268	415	4	18204	49	SLC1A3,SLC1A2,APOE,DTNA
2.519e-02	-3.68	anterograde trans-synaptic signaling	biological process	GO:0098916	415	4	18204	49	SLC1A2,APOE,SLC1A3,DTNA
2.521e-02	-3.68	actin filament bundle	cellular component	GO:0032432	96	2	19108	49	ABLIM1,SORBS1
2.528e-02	-3.68	Diseases of glycosylation	REACTOME pathways	R-HSA-3781865	85	2	10285	30	GPC5,SPON1
2.532e-02	-3.68	PDIA5 (protein disulfide isomerase family A member 5)	protein interactions	10954	96	2	19454	50	NTM,ARHGAP24
2.536e-02	-3.67	perineuronal net	cellular component	GO:0072534	10	1	19108	49	PTPRZ1
2.541e-02	-3.67	Hsp90aa1 (heat shock protein 90, alpha (cytosolic), class A member 1)	protein interactions	15519	10	1	19454	50	QKI
2.541e-02	-3.67	GSG1 (germ cell associated 1)	protein interactions	83445	10	1	19454	50	PITPNC1
2.541e-02	-3.67	Smurf2 (SMAD specific E3 ubiquitin protein ligase 2)	protein interactions	66313	10	1	19454	50	GLIS3
2.541e-02	-3.67	ALKAL2 (ALK and LTK ligand 2)	protein interactions	285016	10	1	19454	50	PON2
2.541e-02	-3.67	TSHZ1 (teashirt zinc finger homeobox 1)	protein interactions	10194	10	1	19454	50	MEIS2
2.541e-02	-3.67	CALB2 (calbindin 2)	protein interactions	794	10	1	19454	50	GPM6A
2.541e-02	-3.67	ZNF852 (zinc finger protein 852)	protein interactions	285346	10	1	19454	50	ARHGAP24
2.541e-02	-3.67	SLC8A2 (solute carrier family 8 member A2)	protein interactions	6543	10	1	19454	50	GPM6A
2.541e-02	-3.67	Mrpl13 (mitochondrial ribosomal protein L13)	protein interactions	68537	10	1	19454	50	QKI
2.541e-02	-3.67	Vbp1 (von Hippel-Lindau binding protein 1)	protein interactions	22327	10	1	19454	50	ABLIM1
2.541e-02	-3.67	ZNF606 (zinc finger protein 606)	protein interactions	80095	10	1	19454	50	ARHGAP24
2.541e-02	-3.67	SERPINB11 (serpin family B member 11)	protein interactions	89778	10	1	19454	50	CPE
2.541e-02	-3.67	P2rx7 (purinergic receptor P2X 7)	protein interactions	29665	10	1	19454	50	PTPRZ1
2.547e-02	-3.67	YWHAZ (tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein zeta)	protein interactions	7534	1138	7	19454	50	APOE,ABLIM1,MACF1,PITPNC1,PARD3B,SORBS1,NHSL1
2.548e-02	-3.67	protein tetramerization	biological process	GO:0051262	92	2	18204	49	AQP4,RYR3
2.581e-02	-3.66	BTG3 (BTG anti-proliferation factor 3)	protein interactions	10950	97	2	19454	50	SPARCL1,CLU
2.589e-02	-3.65	shoulder	COSMIC cancer mutations	shoulder	387	4	16828	49	FGFR3,MACF1,PREX2,CPE
2.591e-02	-3.65	in_situ_epithelial_neoplasm	COSMIC cancer mutations	in_situ_epithelial_neoplasm	9	1	16828	49	FGFR3
2.591e-02	-3.65	compound	COSMIC cancer mutations	compound	9	1	16828	49	FGFR3
2.591e-02	-3.65	ovary-low_malignant_potential_(borderline)_tumour-Brenner_tumour	COSMIC cancer mutations	ovary-low_malignant_potential_(borderline)_tumour-Brenner_tumour	9	1	16828	49	FGFR3
2.591e-02	-3.65	epidermal_nevus	COSMIC cancer mutations	epidermal_nevus	9	1	16828	49	FGFR3
2.591e-02	-3.65	skin-chest-malignant_melanoma-superficial_spreading	COSMIC cancer mutations	skin-chest-malignant_melanoma-superficial_spreading	9	1	16828	49	PREX2
2.591e-02	-3.65	Bowen_disease	COSMIC cancer mutations	Bowen_disease	9	1	16828	49	FGFR3
2.591e-02	-3.65	skin-benign_melanocytic_nevus-congenital	COSMIC cancer mutations	skin-benign_melanocytic_nevus-congenital	9	1	16828	49	FGFR3
2.591e-02	-3.65	skin-upper_leg-malignant_melanoma-superficial_spreading	COSMIC cancer mutations	skin-upper_leg-malignant_melanoma-superficial_spreading	9	1	16828	49	PREX2
2.591e-02	-3.65	skin-other-seborrhoeic_keratosis	COSMIC cancer mutations	skin-other-seborrhoeic_keratosis	9	1	16828	49	FGFR3
2.596e-02	-3.65	Synthesis of 5-eicosatetraenoic acids	REACTOME pathways	R-HSA-2142688	9	1	10285	30	PON2
2.596e-02	-3.65	Terminal pathway of complement	REACTOME pathways	R-HSA-166665	9	1	10285	30	CLU
2.599e-02	-3.65	regulation of extent of cell growth	biological process	GO:0061387	93	2	18204	49	MACF1,APOE
2.612e-02	-3.65	transmembrane transporter activity	molecular function	GO:0022857	1110	7	18094	48	ATP13A4,SLC4A4,GPM6A,SLC1A3,SLC1A2,AQP4,RYR3
2.618e-02	-3.64	axon development	biological process	GO:0061564	420	4	18204	49	CTNNA2,BMPR1B,PTPRZ1,GLI3
2.622e-02	-3.64	polyamine transmembrane transporter activity	molecular function	GO:0015203	10	1	18094	48	ATP13A4
2.622e-02	-3.64	phosphatidylinositol transfer activity	molecular function	GO:0008526	10	1	18094	48	PITPNC1
2.624e-02	-3.64	SYNE3 (spectrin repeat containing nuclear envelope family member 3)	protein interactions	161176	440	4	19454	50	ABLIM1,MACF1,GLI3,SORBS1
2.631e-02	-3.64	FRS2 (fibroblast growth factor receptor substrate 2)	protein interactions	10818	98	2	19454	50	SORBS1,FGFR3
2.631e-02	-3.64	DNAAF2 (dynein axonemal assembly factor 2)	protein interactions	55172	98	2	19454	50	GPM6A,LSAMP
2.653e-02	-3.63	haematopoietic_neoplasm	COSMIC cancer mutations	haematopoietic_neoplasm	11082	39	16828	49	MACF1,PTPRZ1,SPON1,SLC1A3,GLIS3,BMPR1B,NTM,MEIS2,NPAS3,QKI,ATP13A4,CPE,SLC4A4,GPC5,SPARCL1,LSAMP,RYR3,CTNND2,SLC1A2,MAML2,PON2,ABLIM1,DTNA,GLI3,FGFR3,PCDH9,NKAIN3,AMZ2,COL5A3,ACSS1,FBXL7,ARHGAP24,NHSL1,CDH20,MSI2,PAMR1,PARD3B,NFIA,PREX2
2.660e-02	-3.63	negative regulation of sterol biosynthetic process	biological process	GO:0106119	10	1	18204	49	APOE
2.660e-02	-3.63	high-density lipoprotein particle assembly	biological process	GO:0034380	10	1	18204	49	APOE
2.660e-02	-3.63	regulation of CoA-transferase activity	biological process	GO:1905918	10	1	18204	49	APOE
2.660e-02	-3.63	regulation of bone development	biological process	GO:1903010	10	1	18204	49	GLI3
2.660e-02	-3.63	release of sequestered calcium ion into cytosol by endoplasmic reticulum	biological process	GO:1903514	10	1	18204	49	RYR3
2.660e-02	-3.63	negative regulation of cholesterol biosynthetic process	biological process	GO:0045541	10	1	18204	49	APOE
2.660e-02	-3.63	spinal cord motor neuron cell fate specification	biological process	GO:0021520	10	1	18204	49	GLI3
2.660e-02	-3.63	nitric oxide-cGMP-mediated signaling	biological process	GO:0038060	10	1	18204	49	APOE
2.660e-02	-3.63	establishment of centrosome localization	biological process	GO:0051660	10	1	18204	49	PARD3B
2.660e-02	-3.63	regulation of behavioral fear response	biological process	GO:2000822	10	1	18204	49	APOE
2.666e-02	-3.62	TGFBR1 (transforming growth factor beta receptor 1)	protein interactions	7046	251	3	19454	50	PREX2,CLU,BMPR1B
2.666e-02	-3.62	Ig_sub2	interpro domains	IPR003598	239	3	18521	50	LSAMP,FGFR3,NTM
2.668e-02	-3.62	MIR_motif	interpro domains	IPR016093	10	1	18521	50	RYR3
2.668e-02	-3.62	MIP_CS	interpro domains	IPR022357	10	1	18521	50	AQP4
2.668e-02	-3.62	PAS_fold_3	interpro domains	IPR013655	10	1	18521	50	NPAS3
2.668e-02	-3.62	MIR_dom_sf	interpro domains	IPR036300	10	1	18521	50	RYR3
2.668e-02	-3.62	HCO3_transpt-like_TM_dom	interpro domains	IPR011531	10	1	18521	50	SLC4A4
2.668e-02	-3.62	HCO3_transpt_euk	interpro domains	IPR003020	10	1	18521	50	SLC4A4
2.668e-02	-3.62	PTrfase/Anion_transptr	interpro domains	IPR016152	10	1	18521	50	SLC4A4
2.668e-02	-3.62	Endochondral Ossification	WikiPathways	WP474	65	2	5310	21	GLI3,FGFR3
2.680e-02	-3.62	TPP1 (tripeptidyl peptidase 1)	protein interactions	1200	99	2	19454	50	PON2,APOE
2.698e-02	-3.61	developmental growth	biological process	GO:0048589	424	4	18204	49	GLI3,FGFR3,BMPR1B,SLC1A2
2.698e-02	-3.61	growth	biological process	GO:0040007	424	4	18204	49	BMPR1B,SLC1A2,GLI3,FGFR3
2.720e-02	-3.60	skin-mucosal-malignant_melanoma	COSMIC cancer mutations	skin-mucosal-malignant_melanoma	2009	11	16828	49	PCDH9,FGFR3,BMPR1B,COL5A3,ABLIM1,SPARCL1,CTNND2,SORBS1,PREX2,ATP13A4,CPE
2.720e-02	-3.60	mucosal	COSMIC cancer mutations	mucosal	2009	11	16828	49	CTNND2,BMPR1B,SORBS1,COL5A3,PREX2,PCDH9,SPARCL1,FGFR3,ABLIM1,ATP13A4,CPE
2.725e-02	-3.60	GATA_ZN_FINGER_1	prosite domains	PS00344	8	1	12186	42	TRPS1
2.725e-02	-3.60	HP	prosite domains	PS51089	8	1	12186	42	ABLIM1
2.731e-02	-3.60	SUFU (SUFU negative regulator of hedgehog signaling)	protein interactions	51684	100	2	19454	50	GLI3,GLIS3
2.737e-02	-3.60	pancreas-other-adenoma	COSMIC cancer mutations	pancreas-other-adenoma	224	3	16828	49	CTNND2,BMPR1B,PCDH9
2.758e-02	-3.59	monoatomic cation transmembrane transport	biological process	GO:0098655	636	5	18204	49	GPM6A,RYR3,SLC1A3,SLC4A4,ATP13A4
2.767e-02	-3.59	cellular component organization	biological process	GO:0016043	5636	22	18204	49	NFIA,AQP4,PREX2,SLC1A2,BMPR1B,GLI3,SORBS1,RYR3,PARD3B,GPM6A,CTNNA2,ABLIM1,SPARCL1,COL5A3,CLU,CDH20,PTPRZ1,MACF1,CTNND2,APOE,CST3,PITPNC1
2.771e-02	-3.59	actin binding	molecular function	GO:0003779	434	4	18094	48	CTNNA2,ABLIM1,SORBS1,MACF1
2.775e-02	-3.58	PAS_3	pfam domains	PF08447	10	1	17795	50	NPAS3
2.775e-02	-3.58	HCO3_cotransp	pfam domains	PF00955	10	1	17795	50	SLC4A4
2.775e-02	-3.58	MIR	pfam domains	PF02815	10	1	17795	50	RYR3
2.776e-02	-3.58	DYNLL2 (dynein light chain LC8-type 2)	protein interactions	140735	255	3	19454	50	TRPS1,NHSL1,NFIA
2.780e-02	-3.58	signaling	biological process	GO:0023052	4968	20	18204	49	SLC1A3,MACF1,CTNND2,APOE,PITPNC1,CPE,CLU,ARHGAP24,SPARCL1,RYR3,SORBS1,GLI3,DTNA,MAML2,SLC1A2,BMPR1B,NDRG2,NFIA,FGFR3,PREX2
2.781e-02	-3.58	CLEC4A (C-type lectin domain family 4 member A)	protein interactions	50856	101	2	19454	50	FGFR3,CTNNA2
2.786e-02	-3.58	perisynaptic extracellular matrix	cellular component	GO:0098966	11	1	19108	49	PTPRZ1
2.792e-02	-3.58	CCDC17 (coiled-coil domain containing 17)	protein interactions	149483	11	1	19454	50	FGFR3
2.792e-02	-3.58	MSRB1 (methionine sulfoxide reductase B1)	protein interactions	51734	11	1	19454	50	CLU
2.792e-02	-3.58	SYN3 (synapsin III)	protein interactions	8224	11	1	19454	50	GPM6A
2.792e-02	-3.58	NTS (neurotensin)	protein interactions	4922	11	1	19454	50	CPE
2.792e-02	-3.58	IL7 (interleukin 7)	protein interactions	3574	11	1	19454	50	QKI
2.792e-02	-3.58	Batf3 (basic leucine zipper transcription factor, ATF-like 3)	protein interactions	381319	11	1	19454	50	MACF1
2.792e-02	-3.58	Gtf2e2 (general transcription factor II E, polypeptide 2 (beta subunit))	protein interactions	68153	11	1	19454	50	NHSL1
2.792e-02	-3.58	DAZ1 (deleted in azoospermia 1)	protein interactions	1617	11	1	19454	50	QKI
2.792e-02	-3.58	Wipi2 (WD repeat domain, phosphoinositide interacting 2)	protein interactions	74781	11	1	19454	50	MACF1
2.792e-02	-3.58	Cobll1 (Cobl-like 1)	protein interactions	319876	11	1	19454	50	ABLIM1
2.792e-02	-3.58	PTGDR (prostaglandin D2 receptor)	protein interactions	5729	11	1	19454	50	PTGDS
2.792e-02	-3.58	ZNF726 (zinc finger protein 726)	protein interactions	730087	11	1	19454	50	ARHGAP24
2.810e-02	-3.57	nerve development	biological process	GO:0021675	97	2	18204	49	GLI3,SLC1A3
2.810e-02	-3.57	amino acid transmembrane transport	biological process	GO:0003333	97	2	18204	49	SLC1A3,SLC1A2
2.832e-02	-3.56	human chr8q12.3	chromosome location	human chr8q12.3	15	1	26134	50	NKAIN3
2.832e-02	-3.56	MIR7-1 (microRNA 7-1)	protein interactions	407043	102	2	19454	50	MSI2,QKI
2.832e-02	-3.56	KRTAP6-1 (keratin associated protein 6-1)	protein interactions	337966	102	2	19454	50	MEIS2,GLIS3
2.832e-02	-3.56	TMPRSS13 (transmembrane serine protease 13)	protein interactions	84000	102	2	19454	50	SPON1,CPE
2.842e-02	-3.56	SFN (stratifin)	protein interactions	2810	671	5	19454	50	ABLIM1,MACF1,NFIA,SORBS1,PARD3B
2.842e-02	-3.56	trans-synaptic signaling	biological process	GO:0099537	431	4	18204	49	DTNA,SLC1A3,SLC1A2,APOE
2.846e-02	-3.56	VHP	smart domains	SM00153	8	1	9717	35	ABLIM1
2.847e-02	-3.56	regulation of synapse organization	biological process	GO:0050807	246	3	18204	49	GPM6A,APOE,CTNNA2
2.875e-02	-3.55	kidney-carcinoma-renal_cell_carcinoma_unclassified	COSMIC cancer mutations	kidney-carcinoma-renal_cell_carcinoma_unclassified	10	1	16828	49	FGFR3
2.875e-02	-3.55	chiasm	COSMIC cancer mutations	chiasm	10	1	16828	49	QKI
2.875e-02	-3.55	cervical_intraepithelial_neoplasia_Grade_III	COSMIC cancer mutations	cervical_intraepithelial_neoplasia_Grade_III	10	1	16828	49	FGFR3
2.875e-02	-3.55	lung-carcinoma-pleomorphic_carcinoma	COSMIC cancer mutations	lung-carcinoma-pleomorphic_carcinoma	10	1	16828	49	FGFR3
2.875e-02	-3.55	cervix-in_situ_neoplasm-cervical_intraepithelial_neoplasia_Grade_III	COSMIC cancer mutations	cervix-in_situ_neoplasm-cervical_intraepithelial_neoplasia_Grade_III	10	1	16828	49	FGFR3
2.875e-02	-3.55	renal_cell_carcinoma_unclassified	COSMIC cancer mutations	renal_cell_carcinoma_unclassified	10	1	16828	49	FGFR3
2.875e-02	-3.55	skin-back-malignant_melanoma-nodular	COSMIC cancer mutations	skin-back-malignant_melanoma-nodular	10	1	16828	49	PREX2
2.875e-02	-3.55	intradermal	COSMIC cancer mutations	intradermal	10	1	16828	49	FGFR3
2.879e-02	-3.55	FLOT1 (flotillin 1)	protein interactions	10211	453	4	19454	50	SORBS1,DTNA,ABLIM1,MACF1
2.880e-02	-3.55	Bicarbonate transporters	REACTOME pathways	R-HSA-425381	10	1	10285	30	SLC4A4
2.880e-02	-3.55	Signaling by FGFR3 fusions in cancer	REACTOME pathways	R-HSA-8853334	10	1	10285	30	FGFR3
2.880e-02	-3.55	sulfur amino acid transmembrane transporter activity	molecular function	GO:0000099	11	1	18094	48	SLC1A2
2.884e-02	-3.55	RAB6B (RAB6B, member RAS oncogene family)	protein interactions	51560	103	2	19454	50	GPM6A,BMPR1B
2.885e-02	-3.55	inorganic ion homeostasis	biological process	GO:0098771	433	4	18204	49	RYR3,APOE,SLC1A3,ATP13A4
2.893e-02	-3.54	amino acid transmembrane transporter activity	molecular function	GO:0015171	100	2	18094	48	SLC1A3,SLC1A2
2.917e-02	-3.53	phospholipid transport	biological process	GO:0015914	99	2	18204	49	APOE,PITPNC1
2.922e-02	-3.53	regulation of fear response	biological process	GO:1903365	11	1	18204	49	APOE
2.922e-02	-3.53	cell fate commitment involved in pattern specification	biological process	GO:0060581	11	1	18204	49	GLI3
2.922e-02	-3.53	antral ovarian follicle growth	biological process	GO:0001547	11	1	18204	49	BMPR1B
2.922e-02	-3.53	thymocyte apoptotic process	biological process	GO:0070242	11	1	18204	49	GLI3
2.922e-02	-3.53	regulation of receptor catabolic process	biological process	GO:2000644	11	1	18204	49	APOE
2.922e-02	-3.53	intracellular mRNA localization	biological process	GO:0008298	11	1	18204	49	QKI
2.922e-02	-3.53	cellular response to caffeine	biological process	GO:0071313	11	1	18204	49	RYR3
2.922e-02	-3.53	ventral spinal cord interneuron fate commitment	biological process	GO:0060579	11	1	18204	49	GLI3
2.922e-02	-3.53	polyamine transport	biological process	GO:0015846	11	1	18204	49	ATP13A4
2.922e-02	-3.53	negative regulation of cholesterol metabolic process	biological process	GO:0090206	11	1	18204	49	APOE
2.927e-02	-3.53	Post-translational modification: synthesis of GPI-anchored proteins	REACTOME pathways	R-HSA-163125	92	2	10285	30	NTM,LSAMP
2.931e-02	-3.53	Fib_collagen_C	interpro domains	IPR000885	11	1	18521	50	COL5A3
2.936e-02	-3.53	MFHAS1 (multifunctional ROCO family signaling regulator 1)	protein interactions	9258	104	2	19454	50	ARHGAP24,ABLIM1
2.975e-02	-3.52	amide binding	molecular function	GO:0033218	254	3	18094	48	CST3,APOE,CLU
2.979e-02	-3.51	active transmembrane transporter activity	molecular function	GO:0022804	444	4	18094	48	SLC1A2,SLC1A3,SLC4A4,ATP13A4
2.988e-02	-3.51	ABCA2 (ATP binding cassette subfamily A member 2)	protein interactions	20	105	2	19454	50	FGFR3,PON2
3.000e-02	-3.51	Helical hairpin bin	gene3d domains	1.10.287.570	10	1	14470	44	SLC4A4
3.022e-02	-3.50	GATAZNFINGER	prints domains	PR00619	8	1	5227	20	TRPS1
3.022e-02	-3.50	LIPOCALIN	prints domains	PR00179	8	1	5227	20	PTGDS
3.027e-02	-3.50	regulation of synapse structure or activity	biological process	GO:0050803	252	3	18204	49	CTNNA2,APOE,GPM6A
3.030e-02	-3.50	cell communication	biological process	GO:0007154	5010	20	18204	49	PREX2,NDRG2,FGFR3,NFIA,MAML2,BMPR1B,SLC1A2,DTNA,GLI3,SPARCL1,RYR3,SORBS1,CLU,ARHGAP24,CPE,SLC1A3,APOE,PITPNC1,CTNND2,MACF1
3.035e-02	-3.49	synapse-associated extracellular matrix	cellular component	GO:0099535	12	1	19108	49	PTPRZ1
3.035e-02	-3.49	banded collagen fibril	cellular component	GO:0098643	12	1	19108	49	COL5A3
3.035e-02	-3.49	fibrillar collagen trimer	cellular component	GO:0005583	12	1	19108	49	COL5A3
3.040e-02	-3.49	USP30 (ubiquitin specific peptidase 30)	protein interactions	84749	106	2	19454	50	FGFR3,QKI
3.042e-02	-3.49	UGT1A9 (UDP glucuronosyltransferase family 1 member A9)	protein interactions	54600	12	1	19454	50	PON2
3.042e-02	-3.49	ZNF235 (zinc finger protein 235)	protein interactions	9310	12	1	19454	50	ARHGAP24
3.042e-02	-3.49	MMP25 (matrix metallopeptidase 25)	protein interactions	64386	12	1	19454	50	CLU
3.042e-02	-3.49	BAMBI (BMP and activin membrane bound inhibitor)	protein interactions	25805	12	1	19454	50	BMPR1B
3.042e-02	-3.49	LOC102724560 (cystathionine beta-synthase like)	protein interactions	102724560	12	1	19454	50	ARHGAP24
3.042e-02	-3.49	FAM222A (family with sequence similarity 222 member A)	protein interactions	84915	12	1	19454	50	MEIS2
3.042e-02	-3.49	CA4 (carbonic anhydrase 4)	protein interactions	762	12	1	19454	50	SLC4A4
3.042e-02	-3.49	ART4 (ADP-ribosyltransferase 4 (inactive) (Dombrock blood group))	protein interactions	420	12	1	19454	50	GPM6A
3.042e-02	-3.49	PROK2 (prokineticin 2)	protein interactions	60675	12	1	19454	50	CPE
3.042e-02	-3.49	ZNF91 (zinc finger protein 91)	protein interactions	7644	12	1	19454	50	ARHGAP24
3.042e-02	-3.49	upper_aerodigestive_tract	COSMIC cancer mutations	upper_aerodigestive_tract	13181	44	16828	49	LSAMP,RYR3,SLC1A2,BMPR1B,PTGDS,NHSL1,PAMR1,MSI2,GPM6A,SORBS1,NFIA,TRPS1,MAML2,CLU,ABLIM1,COL5A3,FBXL7,ACSS1,CST3,NPAS3,QKI,ATP13A4,SLC4A4,NTM,CTNND2,GPC5,MACF1,PITPNC1,GLIS3,PTPRZ1,NDRG2,SPON1,SLC1A3,ARHGAP24,CDH20,PREX2,PARD3B,DTNA,APOE,GLI3,FGFR3,PCDH9,NKAIN3,AMZ2
3.049e-02	-3.49	COLFI	pfam domains	PF01410	11	1	17795	50	COL5A3
3.060e-02	-3.49	CYSTATIN	prosite domains	PS00287	9	1	12186	42	CST3
3.066e-02	-3.48	Salivary secretion	KEGG pathways	hsa04970	90	2	7161	22	CST3,RYR3
3.066e-02	-3.48	Salivary secretion	KEGG pathways	ko04970	90	2	7161	22	RYR3,CST3
3.082e-02	-3.48	artery development	biological process	GO:0060840	102	2	18204	49	APOE,GLI3
3.092e-02	-3.48	POMK (protein O-mannose kinase)	protein interactions	84197	266	3	19454	50	CLU,PON2,BMPR1B
3.095e-02	-3.48	peptide binding	molecular function	GO:0042277	258	3	18094	48	CLU,APOE,CST3
3.122e-02	-3.47	cellular response to endogenous stimulus	biological process	GO:0071495	1135	7	18204	49	BMPR1B,SLC1A2,FGFR3,NFIA,RYR3,SORBS1,SLC1A3
3.122e-02	-3.47	Phase I biotransformations, non P450	WikiPathways	WP136	8	1	5310	21	PON2
3.138e-02	-3.46	regulation of neural precursor cell proliferation	biological process	GO:2000177	103	2	18204	49	GLI3,PTPRZ1
3.147e-02	-3.46	BIN1 (bridging integrator 1)	protein interactions	274	108	2	19454	50	GPM6A,CLU
3.147e-02	-3.46	FKBP1A (FKBP prolyl isomerase 1A)	protein interactions	2280	108	2	19454	50	RYR3,MSI2
3.147e-02	-3.46	EN1 (engrailed homeobox 1)	protein interactions	2019	108	2	19454	50	NFIA,TRPS1
3.147e-02	-3.46	GGT7 (gamma-glutamyltransferase 7)	protein interactions	2686	108	2	19454	50	ARHGAP24,NDRG2
3.147e-02	-3.46	PAX8 (paired box 8)	protein interactions	7849	108	2	19454	50	TRPS1,NFIA
3.149e-02	-3.46	PFN1 (profilin 1)	protein interactions	5216	466	4	19454	50	NHSL1,ABLIM1,ARHGAP24,MACF1
3.151e-02	-3.46	VCL (vinculin)	protein interactions	7414	268	3	19454	50	ARHGAP24,MACF1,SORBS1
3.151e-02	-3.46	protein complex oligomerization	biological process	GO:0051259	256	3	18204	49	AQP4,SLC1A2,RYR3
3.158e-02	-3.46	skin-hand-malignant_melanoma-acral_lentiginous	COSMIC cancer mutations	skin-hand-malignant_melanoma-acral_lentiginous	11	1	16828	49	PREX2
3.158e-02	-3.46	congenital	COSMIC cancer mutations	congenital	11	1	16828	49	FGFR3
3.158e-02	-3.46	pleomorphic_carcinoma	COSMIC cancer mutations	pleomorphic_carcinoma	11	1	16828	49	FGFR3
3.158e-02	-3.46	oncocytoma	COSMIC cancer mutations	oncocytoma	11	1	16828	49	FGFR3
3.158e-02	-3.46	skin-neck-carcinoma-basal_cell_carcinoma	COSMIC cancer mutations	skin-neck-carcinoma-basal_cell_carcinoma	11	1	16828	49	FGFR3
3.158e-02	-3.46	kidney-other-oncocytoma	COSMIC cancer mutations	kidney-other-oncocytoma	11	1	16828	49	FGFR3
3.158e-02	-3.46	prostate-hyperplasia	COSMIC cancer mutations	prostate-hyperplasia	11	1	16828	49	FGFR3
3.158e-02	-3.46	skin-back-malignant_melanoma-superficial_spreading	COSMIC cancer mutations	skin-back-malignant_melanoma-superficial_spreading	11	1	16828	49	PREX2
3.158e-02	-3.46	skin-scalp-carcinoma-basal_cell_carcinoma	COSMIC cancer mutations	skin-scalp-carcinoma-basal_cell_carcinoma	11	1	16828	49	FGFR3
3.158e-02	-3.46	seborrhoeic_keratosis	COSMIC cancer mutations	seborrhoeic_keratosis	11	1	16828	49	FGFR3
3.184e-02	-3.45	neurotransmitter-gated ion channel clustering	biological process	GO:0072578	12	1	18204	49	APOE
3.184e-02	-3.45	negative thymic T cell selection	biological process	GO:0045060	12	1	18204	49	GLI3
3.184e-02	-3.45	microglia differentiation	biological process	GO:0014004	12	1	18204	49	QKI
3.184e-02	-3.45	negative regulation of collagen metabolic process	biological process	GO:0010713	12	1	18204	49	CST3
3.184e-02	-3.45	auditory behavior	biological process	GO:0031223	12	1	18204	49	SLC1A3
3.184e-02	-3.45	sulfur amino acid transport	biological process	GO:0000101	12	1	18204	49	SLC1A2
3.184e-02	-3.45	positive regulation of extrinsic apoptotic signaling pathway via death domain receptors	biological process	GO:1902043	12	1	18204	49	BMPR1B
3.184e-02	-3.45	mammalian oogenesis stage	biological process	GO:0022605	12	1	18204	49	BMPR1B
3.184e-02	-3.45	regulation of blood vessel remodeling	biological process	GO:0060312	12	1	18204	49	CST3
3.193e-02	-3.44	Lipocalin	interpro domains	IPR002345	12	1	18521	50	PTGDS
3.193e-02	-3.44	MAD_homology1_Dwarfin-type	interpro domains	IPR003619	12	1	18521	50	NFIA
3.193e-02	-3.44	Lipocalin_CS	interpro domains	IPR022272	12	1	18521	50	PTGDS
3.193e-02	-3.44	TGFB_receptor	interpro domains	IPR000333	12	1	18521	50	BMPR1B
3.197e-02	-3.44	FOLN	smart domains	SM00274	9	1	9717	35	SPARCL1
3.200e-02	-3.44	MIR34B (microRNA 34b)	protein interactions	407041	109	2	19454	50	MSI2,QKI
3.213e-02	-3.44	ATXN1 (ataxin 1)	protein interactions	6310	469	4	19454	50	PTGDS,QKI,NFIA,CST3
3.251e-02	-3.43	neural precursor cell proliferation	biological process	GO:0061351	105	2	18204	49	GLI3,NFIA
3.254e-02	-3.43	SCARB1 (scavenger receptor class B member 1)	protein interactions	949	110	2	19454	50	PON2,APOE
3.254e-02	-3.43	LZTR1 (leucine zipper like post translational regulator 1)	protein interactions	8216	110	2	19454	50	PARD3B,BMPR1B
3.275e-02	-3.42	regulation of plasma membrane bounded cell projection organization	biological process	GO:0120035	666	5	18204	49	ARHGAP24,GPM6A,APOE,MACF1,CTNNA2
3.276e-02	-3.42	prostate-carcinoma-adenocarcinoma	COSMIC cancer mutations	prostate-carcinoma-adenocarcinoma	12379	42	16828	49	SLC1A3,SPON1,NDRG2,PTPRZ1,BMPR1B,GLIS3,PITPNC1,MACF1,SPARCL1,GPC5,SLC1A2,CTNND2,RYR3,LSAMP,NTM,CPE,ATP13A4,AQP4,QKI,NPAS3,MEIS2,NKAIN3,PCDH9,GLI3,FGFR3,FBXL7,ACSS1,COL5A3,CLU,ABLIM1,PON2,MAML2,TRPS1,NFIA,PARD3B,SORBS1,GPM6A,PREX2,CDH20,PAMR1,NHSL1,ARHGAP24
3.281e-02	-3.42	distal axon	cellular component	GO:0150034	273	3	19108	49	NDRG2,PCDH9,GPM6A
3.284e-02	-3.42	chylomicron	cellular component	GO:0042627	13	1	19108	49	APOE
3.291e-02	-3.41	ANKH (ANKH inorganic pyrophosphate transport regulator)	protein interactions	56172	13	1	19454	50	APOE
3.291e-02	-3.41	RAB3C (RAB3C, member RAS oncogene family)	protein interactions	115827	13	1	19454	50	GPM6A
3.291e-02	-3.41	ST3GAL5 (ST3 beta-galactoside alpha-2,3-sialyltransferase 5)	protein interactions	8869	13	1	19454	50	PON2
3.291e-02	-3.41	Pias1 (protein inhibitor of activated STAT 1)	protein interactions	56469	13	1	19454	50	GLI3
3.291e-02	-3.41	TBCC (tubulin folding cofactor C)	protein interactions	6903	13	1	19454	50	NTM
3.291e-02	-3.41	MAB21L1 (mab-21 like 1)	protein interactions	4081	13	1	19454	50	MEIS2
3.291e-02	-3.41	Rbm47 (RNA binding motif protein 47)	protein interactions	245945	13	1	19454	50	QKI
3.291e-02	-3.41	CCN5 (cellular communication network factor 5)	protein interactions	8839	13	1	19454	50	AMZ2
3.291e-02	-3.41	ZNF718 (zinc finger protein 718)	protein interactions	255403	13	1	19454	50	ARHGAP24
3.291e-02	-3.41	PCDHA2 (protocadherin alpha 2)	protein interactions	56146	13	1	19454	50	NFIA
3.296e-02	-3.41	Carboxypeptidase-like, regulatory domain	gene3d domains	2.60.40.1120	11	1	14470	44	CPE
3.302e-02	-3.41	endoplasmic reticulum	cellular component	GO:0005783	2051	10	19108	49	SPON1,ATP13A4,COL5A3,CLU,CST3,RYR3,SPARCL1,PTGDS,APOE,FGFR3
3.307e-02	-3.41	pigmentation	biological process	GO:0043473	106	2	18204	49	GLI3,APOE
3.309e-02	-3.41	cell-cell adhesion via plasma-membrane adhesion molecules	biological process	GO:0098742	261	3	18204	49	PCDH9,CDH20,SPARCL1
3.321e-02	-3.40	CarboxypepD_reg	pfam domains	PF13620	12	1	17795	50	CPE
3.321e-02	-3.40	MH1	pfam domains	PF03165	12	1	17795	50	NFIA
3.330e-02	-3.40	Hedgehog signaling	KEGG pathways	hsa_M00678	11	1	7161	22	GLI3
3.330e-02	-3.40	Hedgehog signaling	KEGG pathways	M00678	11	1	7161	22	GLI3
3.363e-02	-3.39	TBR1 (T-box brain transcription factor 1)	protein interactions	10716	112	2	19454	50	NFIA,TRPS1
3.363e-02	-3.39	TSC22D4 (TSC22 domain family member 4)	protein interactions	81628	112	2	19454	50	ABLIM1,CLU
3.363e-02	-3.39	CEP170P1 (centrosomal protein 170 pseudogene 1)	protein interactions	645455	112	2	19454	50	TRPS1,MACF1
3.387e-02	-3.39	skin-arm-malignant_melanoma	COSMIC cancer mutations	skin-arm-malignant_melanoma	1308	8	16828	49	SORBS1,COL5A3,TRPS1,PARD3B,SLC4A4,MACF1,NPAS3,NTM
3.389e-02	-3.38	human chr7q31.32	chromosome location	human chr7q31.32	18	1	26134	50	PTPRZ1
3.389e-02	-3.38	human chr18q21.33	chromosome location	human chr18q21.33	18	1	26134	50	CDH20
3.394e-02	-3.38	NAKATPASE	prints domains	PR00121	9	1	5227	20	ATP13A4
3.395e-02	-3.38	MIP	prosite domains	PS00221	10	1	12186	42	AQP4
3.395e-02	-3.38	MIR	prosite domains	PS50919	10	1	12186	42	RYR3
3.395e-02	-3.38	transforming growth factor beta receptor activity	molecular function	GO:0005024	13	1	18094	48	BMPR1B
3.395e-02	-3.38	monoatomic cation:bicarbonate symporter activity	molecular function	GO:0140410	13	1	18094	48	SLC4A4
3.396e-02	-3.38	regulation of nervous system development	biological process	GO:0051960	456	4	18204	49	MACF1,GLI3,PTPRZ1,QKI
3.400e-02	-3.38	calcium ion binding	molecular function	GO:0005509	683	5	18094	48	MACF1,RYR3,PAMR1,PCDH9,SPARCL1
3.405e-02	-3.38	NR3C1 (nuclear receptor subfamily 3 group C member 1)	protein interactions	2908	950	6	19454	50	PON2,ATP13A4,NFIA,TRPS1,SLC1A3,CTNND2
3.408e-02	-3.38	organic anion transmembrane transporter activity	molecular function	GO:0008514	268	3	18094	48	SLC1A2,SLC1A3,SLC4A4
3.440e-02	-3.37	skin-face-carcinoma-basal_cell_carcinoma	COSMIC cancer mutations	skin-face-carcinoma-basal_cell_carcinoma	12	1	16828	49	FGFR3
3.440e-02	-3.37	skin-benign_melanocytic_nevus	COSMIC cancer mutations	skin-benign_melanocytic_nevus	12	1	16828	49	FGFR3
3.440e-02	-3.37	cervix-carcinoma-mixed_adenosquamous_carcinoma	COSMIC cancer mutations	cervix-carcinoma-mixed_adenosquamous_carcinoma	12	1	16828	49	FGFR3
3.440e-02	-3.37	central_nervous_system-fourth_ventricle-glioma-astrocytoma_Grade_I	COSMIC cancer mutations	central_nervous_system-fourth_ventricle-glioma-astrocytoma_Grade_I	12	1	16828	49	QKI
3.440e-02	-3.37	skin-abdomen-malignant_melanoma-nodular	COSMIC cancer mutations	skin-abdomen-malignant_melanoma-nodular	12	1	16828	49	PREX2
3.443e-02	-3.37	positive regulation of cell development	biological process	GO:0010720	458	4	18204	49	GLI3,PTPRZ1,QKI,MACF1
3.444e-02	-3.37	ventral spinal cord interneuron differentiation	biological process	GO:0021514	13	1	18204	49	GLI3
3.444e-02	-3.37	prepulse inhibition	biological process	GO:0060134	13	1	18204	49	CTNNA2
3.444e-02	-3.37	negative T cell selection	biological process	GO:0043383	13	1	18204	49	GLI3
3.444e-02	-3.37	regulation of dendritic spine maintenance	biological process	GO:1902950	13	1	18204	49	APOE
3.444e-02	-3.37	glial cell fate commitment	biological process	GO:0021781	13	1	18204	49	NFIA
3.444e-02	-3.37	phospholipid efflux	biological process	GO:0033700	13	1	18204	49	APOE
3.446e-02	-3.37	FGFR3 mutant receptor activation	REACTOME pathways	R-HSA-2033514	12	1	10285	30	FGFR3
3.446e-02	-3.37	Signaling by activated point mutants of FGFR3	REACTOME pathways	R-HSA-1839130	12	1	10285	30	FGFR3
3.446e-02	-3.37	Defective EXT2 causes exostoses 2	REACTOME pathways	R-HSA-3656237	12	1	10285	30	GPC5
3.446e-02	-3.37	Defective EXT1 causes exostoses 1, TRPS2 and CHDS	REACTOME pathways	R-HSA-3656253	12	1	10285	30	GPC5
3.446e-02	-3.37	Ethanol oxidation	REACTOME pathways	R-HSA-71384	12	1	10285	30	ACSS1
3.456e-02	-3.37	animal organ development	biological process	GO:0048513	2846	13	18204	49	CPE,COL5A3,GPM6A,MEIS2,CTNNA2,ABLIM1,PCDH9,GLI3,BMPR1B,SLC1A2,NFIA,FGFR3,NDRG2
3.459e-02	-3.36	small molecule binding	molecular function	GO:0036094	6197	23	18094	48	PTGDS,SLC1A3,SPARCL1,ATP13A4,RYR3,PON2,BMPR1B,GLI3,MACF1,SPON1,PITPNC1,APOE,TRPS1,DTNA,PAMR1,ACSS1,CPE,FGFR3,PCDH9,ABLIM1,SLC1A2,AMZ2,GLIS3
3.466e-02	-3.36	synaptic signaling	biological process	GO:0099536	459	4	18204	49	SLC1A2,APOE,SLC1A3,DTNA
3.466e-02	-3.36	small molecule biosynthetic process	biological process	GO:0044283	459	4	18204	49	PTGDS,SLC1A3,ACSS1,QKI
3.474e-02	-3.36	ORF3b (ORF3b protein)	protein interactions	1489670	114	2	19454	50	PCDH9,MACF1
3.475e-02	-3.36	Visual phototransduction	REACTOME pathways	R-HSA-2187338	101	2	10285	30	GPC5,APOE
3.481e-02	-3.36	postsynapse organization	biological process	GO:0099173	109	2	18204	49	CTNND2,APOE
3.481e-02	-3.36	long-chain fatty acid metabolic process	biological process	GO:0001676	109	2	18204	49	QKI,PTGDS
3.481e-02	-3.36	Disease	REACTOME pathways	R-HSA-1643685	858	6	10285	30	MAML2,FGFR3,MACF1,SPON1,QKI,GPC5
3.500e-02	-3.35	Cadherin_CS	interpro domains	IPR020894	109	2	18521	50	PCDH9,CDH20
3.506e-02	-3.35	chemical homeostasis	biological process	GO:0048878	914	6	18204	49	AQP4,SLC4A4,ATP13A4,SLC1A3,APOE,RYR3
3.506e-02	-3.35	Tgif disruption of Shh signaling	WikiPathways	WP3674	9	1	5310	21	GLI3
3.530e-02	-3.34	SULF2 (sulfatase 2)	protein interactions	55959	115	2	19454	50	SPON1,PON2
3.530e-02	-3.34	TBXT (T-box transcription factor T)	protein interactions	6862	115	2	19454	50	TRPS1,NFIA
3.532e-02	-3.34	chromaffin granule	cellular component	GO:0042583	14	1	19108	49	CLU
3.540e-02	-3.34	Stag2 (STAG2 cohesin complex component)	protein interactions	20843	14	1	19454	50	CLU
3.540e-02	-3.34	RHEBL1 (RHEB like 1)	protein interactions	121268	14	1	19454	50	BMPR1B
3.540e-02	-3.34	FGF7 (fibroblast growth factor 7)	protein interactions	2252	14	1	19454	50	FGFR3
3.540e-02	-3.34	Aifm1 (apoptosis-inducing factor, mitochondrion-associated 1)	protein interactions	26926	14	1	19454	50	CLU
3.540e-02	-3.34	KRTAP22-1 (keratin associated protein 22-1)	protein interactions	337979	14	1	19454	50	MEIS2
3.540e-02	-3.34	SLC1A2 (solute carrier family 1 member 2)	protein interactions	6506	14	1	19454	50	SLC1A2
3.540e-02	-3.34	MB (myoglobin)	protein interactions	4151	14	1	19454	50	MAML2
3.540e-02	-3.34	Asap1 (ArfGAP with SH3 domain, ankyrin repeat and PH domain1)	protein interactions	13196	14	1	19454	50	MACF1
3.540e-02	-3.34	IFNA8 (interferon alpha 8)	protein interactions	3445	14	1	19454	50	APOE
3.540e-02	-3.34	Nedd4 (neural precursor cell expressed, developmentally down-regulated 4)	protein interactions	17999	14	1	19454	50	GLIS3
3.546e-02	-3.34	MIR	smart domains	SM00472	10	1	9717	35	RYR3
3.558e-02	-3.34	LYN (LYN proto-oncogene, Src family tyrosine kinase)	protein interactions	4067	713	5	19454	50	ABLIM1,MACF1,DTNA,MSI2,SLC1A3
3.559e-02	-3.34	side of membrane	cellular component	GO:0098552	715	5	19108	49	AQP4,LSAMP,DTNA,GPC5,NTM
3.570e-02	-3.33	blood microparticle	cellular component	GO:0072562	116	2	19108	49	CLU,APOE
3.573e-02	-3.33	positive regulation of cellular metabolic process	biological process	GO:0031325	3164	14	18204	49	MEIS2,SORBS1,NPAS3,GLI3,SPON1,BMPR1B,MAML2,GLIS3,SLC4A4,FGFR3,NFIA,QKI,APOE,CLU
3.574e-02	-3.33	human chr6q24.1	chromosome location	human chr6q24.1	19	1	26134	50	NHSL1
3.574e-02	-3.33	human chr5p15.2	chromosome location	human chr5p15.2	19	1	26134	50	CTNND2
3.574e-02	-3.33	human chr11q25	chromosome location	human chr11q25	19	1	26134	50	NTM
3.586e-02	-3.33	RBBP8 (RB binding protein 8, endonuclease)	protein interactions	5932	116	2	19454	50	CLU,CTNNA2
3.586e-02	-3.33	SKIL (SKI like proto-oncogene)	protein interactions	6498	116	2	19454	50	SPARCL1,MACF1
3.590e-02	-3.33	Alpha-catenin/vinculin-like	gene3d domains	1.20.120.230	12	1	14470	44	CTNNA2
3.593e-02	-3.33	regulation of cell projection organization	biological process	GO:0031344	683	5	18204	49	ARHGAP24,CTNNA2,GPM6A,APOE,MACF1
3.593e-02	-3.33	skin-upper_leg-malignant_melanoma	COSMIC cancer mutations	skin-upper_leg-malignant_melanoma	850	6	16828	49	PREX2,ACSS1,GLIS3,PCDH9,NFIA,PAMR1
3.619e-02	-3.32	cell migration	biological process	GO:0016477	921	6	18204	49	GPM6A,GPC5,CTNNA2,CDH20,GLI3,ARHGAP24
3.642e-02	-3.31	ELK3 (ETS transcription factor ELK3)	protein interactions	2004	117	2	19454	50	TRPS1,NFIA
3.642e-02	-3.31	ZMYND19 (zinc finger MYND-type containing 19)	protein interactions	116225	117	2	19454	50	SPON1,CTNND2
3.646e-02	-3.31	skin-scalp-malignant_melanoma	COSMIC cancer mutations	skin-scalp-malignant_melanoma	634	5	16828	49	PREX2,SORBS1,PTPRZ1,NTM,NFIA
3.647e-02	-3.31	HYOU1 (hypoxia up-regulated 1)	protein interactions	10525	284	3	19454	50	FGFR3,CPE,CLU
3.652e-02	-3.31	microtubule minus-end binding	molecular function	GO:0051011	14	1	18094	48	MACF1
3.657e-02	-3.31	regulation of gliogenesis	biological process	GO:0014013	112	2	18204	49	QKI,PTPRZ1
3.661e-02	-3.31	SNX27 (sorting nexin 27)	protein interactions	81609	489	4	19454	50	CLU,ABLIM1,COL5A3,SLC1A3
3.680e-02	-3.30	P4HA1 (prolyl 4-hydroxylase subunit alpha 1)	protein interactions	5033	285	3	19454	50	APOE,PON2,DTNA
3.704e-02	-3.30	cell surface receptor signaling pathway	biological process	GO:0007166	1992	10	18204	49	CPE,GLI3,MACF1,SORBS1,CTNND2,NFIA,FGFR3,NDRG2,MAML2,BMPR1B
3.704e-02	-3.30	negative regulation of long-term synaptic potentiation	biological process	GO:1900272	14	1	18204	49	APOE
3.704e-02	-3.30	cerebrospinal fluid circulation	biological process	GO:0090660	14	1	18204	49	AQP4
3.704e-02	-3.30	sodium ion export across plasma membrane	biological process	GO:0036376	14	1	18204	49	SLC4A4
3.704e-02	-3.30	positive regulation of phospholipid transport	biological process	GO:2001140	14	1	18204	49	APOE
3.704e-02	-3.30	radial glial cell differentiation	biological process	GO:0060019	14	1	18204	49	GLI3
3.704e-02	-3.30	cellular response to purine-containing compound	biological process	GO:0071415	14	1	18204	49	RYR3
3.704e-02	-3.30	layer formation in cerebral cortex	biological process	GO:0021819	14	1	18204	49	GLI3
3.704e-02	-3.30	acetyl-CoA biosynthetic process	biological process	GO:0006085	14	1	18204	49	ACSS1
3.704e-02	-3.30	mechanosensory behavior	biological process	GO:0007638	14	1	18204	49	SLC1A3
3.704e-02	-3.30	positive regulation of myoblast proliferation	biological process	GO:2000288	14	1	18204	49	MEIS2
3.704e-02	-3.30	glutathione biosynthetic process	biological process	GO:0006750	14	1	18204	49	SLC1A2
3.715e-02	-3.29	Aquaporin-like	interpro domains	IPR023271	14	1	18521	50	AQP4
3.715e-02	-3.29	MIP	interpro domains	IPR000425	14	1	18521	50	AQP4
3.721e-02	-3.29	Brenner_tumour	COSMIC cancer mutations	Brenner_tumour	13	1	16828	49	FGFR3
3.721e-02	-3.29	skin-scalp-malignant_melanoma-nodular	COSMIC cancer mutations	skin-scalp-malignant_melanoma-nodular	13	1	16828	49	PREX2
3.721e-02	-3.29	central_nervous_system-hypothalamus-glioma-astrocytoma_Grade_I	COSMIC cancer mutations	central_nervous_system-hypothalamus-glioma-astrocytoma_Grade_I	13	1	16828	49	QKI
3.721e-02	-3.29	skin-shoulder-malignant_melanoma-nodular	COSMIC cancer mutations	skin-shoulder-malignant_melanoma-nodular	13	1	16828	49	PREX2
3.721e-02	-3.29	skin-back-carcinoma-basal_cell_carcinoma	COSMIC cancer mutations	skin-back-carcinoma-basal_cell_carcinoma	13	1	16828	49	FGFR3
3.721e-02	-3.29	endometrium-ovary-endometriosis	COSMIC cancer mutations	endometrium-ovary-endometriosis	13	1	16828	49	FGFR3
3.721e-02	-3.29	cervix-carcinoma-adenocarcinoma	COSMIC cancer mutations	cervix-carcinoma-adenocarcinoma	13	1	16828	49	FGFR3
3.728e-02	-3.29	GATA_ZN_FINGER_2	prosite domains	PS50114	11	1	12186	42	TRPS1
3.728e-02	-3.29	LIPOCALIN	prosite domains	PS00213	11	1	12186	42	PTGDS
3.728e-02	-3.29	NC1_FIB	prosite domains	PS51461	11	1	12186	42	COL5A3
3.728e-02	-3.29	FGFR3 ligand binding and activation	REACTOME pathways	R-HSA-190239	13	1	10285	30	FGFR3
3.728e-02	-3.29	Passive transport by Aquaporins	REACTOME pathways	R-HSA-432047	13	1	10285	30	AQP4
3.728e-02	-3.29	NOTCH2 intracellular domain regulates transcription	REACTOME pathways	R-HSA-2197563	13	1	10285	30	MAML2
3.728e-02	-3.29	Phospholipase C-mediated cascade; FGFR3	REACTOME pathways	R-HSA-5654227	13	1	10285	30	FGFR3
3.728e-02	-3.29	Notch-HLH transcription pathway	REACTOME pathways	R-HSA-350054	13	1	10285	30	MAML2
3.728e-02	-3.29	FGFR3c ligand binding and activation	REACTOME pathways	R-HSA-190372	13	1	10285	30	FGFR3
3.745e-02	-3.28	HSPA1B (heat shock protein family A (Hsp70) member 1B)	protein interactions	3304	287	3	19454	50	NDRG2,ARHGAP24,FGFR3
3.745e-02	-3.28	PARD3 (par-3 family cell polarity regulator)	protein interactions	56288	287	3	19454	50	PARD3B,SORBS1,DTNA
3.750e-02	-3.28	central_nervous_system-cerebellum-glioma-astrocytoma_Grade_I	COSMIC cancer mutations	central_nervous_system-cerebellum-glioma-astrocytoma_Grade_I	105	2	16828	49	QKI,GPC5
3.754e-02	-3.28	basal plasma membrane	cellular component	GO:0009925	288	3	19108	49	SLC4A4,SLC1A3,AQP4
3.757e-02	-3.28	EF_HAND_2	prosite domains	PS50222	215	3	12186	42	MACF1,SPARCL1,RYR3
3.759e-02	-3.28	human chr8p21.1	chromosome location	human chr8p21.1	20	1	26134	50	CLU
3.764e-02	-3.28	HCO3TRNSPORT	prints domains	PR01231	10	1	5227	20	SLC4A4
3.777e-02	-3.28	DDX27 (DEAD-box helicase 27)	protein interactions	55661	288	3	19454	50	NTM,FGFR3,ARHGAP24
3.780e-02	-3.28	axolemma	cellular component	GO:0030673	15	1	19108	49	SLC1A2
3.780e-02	-3.28	low-density lipoprotein particle	cellular component	GO:0034362	15	1	19108	49	APOE
3.788e-02	-3.27	ZNF714 (zinc finger protein 714)	protein interactions	148206	15	1	19454	50	ARHGAP24
3.788e-02	-3.27	ZNF813 (zinc finger protein 813)	protein interactions	126017	15	1	19454	50	ARHGAP24
3.788e-02	-3.27	ZNF616 (zinc finger protein 616)	protein interactions	90317	15	1	19454	50	ARHGAP24
3.788e-02	-3.27	TMEM255B (transmembrane protein 255B)	protein interactions	348013	15	1	19454	50	AMZ2
3.788e-02	-3.27	FGF9 (fibroblast growth factor 9)	protein interactions	2254	15	1	19454	50	FGFR3
3.788e-02	-3.27	IGSF1 (immunoglobulin superfamily member 1)	protein interactions	3547	15	1	19454	50	BMPR1B
3.798e-02	-3.27	Cadherin-like_dom	interpro domains	IPR002126	114	2	18521	50	CDH20,PCDH9
3.808e-02	-3.27	learning or memory	biological process	GO:0007611	276	3	18204	49	PTPRZ1,MEIS2,APOE
3.809e-02	-3.27	thyroid-carcinoma	COSMIC cancer mutations	thyroid-carcinoma	4126	18	16828	49	ATP13A4,AQP4,CPE,SPARCL1,TRPS1,GPC5,NFIA,LSAMP,CTNND2,RYR3,MACF1,DTNA,PTPRZ1,FGFR3,PCDH9,ACSS1,GLIS3,COL5A3
3.855e-02	-3.26	calcium channel activity	molecular function	GO:0005262	117	2	18094	48	RYR3,GPM6A
3.864e-02	-3.25	MIP	pfam domains	PF00230	14	1	17795	50	AQP4
3.864e-02	-3.25	GATA	pfam domains	PF00320	14	1	17795	50	TRPS1
3.872e-02	-3.25	MED15 (mediator complex subunit 15)	protein interactions	51586	121	2	19454	50	QKI,NFIA
3.880e-02	-3.25	skin-scalp-carcinoma-squamous_cell_carcinoma	COSMIC cancer mutations	skin-scalp-carcinoma-squamous_cell_carcinoma	1596	9	16828	49	SLC4A4,ATP13A4,MACF1,TRPS1,GPC5,PTPRZ1,FGFR3,LSAMP,COL5A3
3.886e-02	-3.25	positive regulation of macromolecule biosynthetic process	biological process	GO:0010557	2592	12	18204	49	APOE,CLU,GLI3,SPON1,SORBS1,MEIS2,NPAS3,GLIS3,QKI,NFIA,BMPR1B,MAML2
3.888e-02	-3.25	Composition of Lipid Particles	WikiPathways	WP3601	10	1	5310	21	APOE
3.894e-02	-3.25	COLFI	smart domains	SM00038	11	1	9717	35	COL5A3
3.896e-02	-3.25	Propanoate Metabolism	SMPDB pathways	SMP0000016	18	1	1369	3	ACSS1
3.896e-02	-3.25	Methylmalonic Aciduria Due to Cobalamin-Related Disorders	SMPDB pathways	SMP0000201	18	1	1369	3	ACSS1
3.896e-02	-3.25	Malonic Aciduria	SMPDB pathways	SMP0000198	18	1	1369	3	ACSS1
3.896e-02	-3.25	Malonyl-CoA Decarboxylase Deficiency	SMPDB pathways	SMP0000502	18	1	1369	3	ACSS1
3.908e-02	-3.24	AMP binding	molecular function	GO:0016208	15	1	18094	48	ACSS1
3.908e-02	-3.24	neurexin family protein binding	molecular function	GO:0042043	15	1	18094	48	CPE
3.908e-02	-3.24	phosphatidylglycerol binding	molecular function	GO:1901611	15	1	18094	48	PITPNC1
3.914e-02	-3.24	skin-leg-malignant_melanoma-nodular	COSMIC cancer mutations	skin-leg-malignant_melanoma-nodular	258	3	16828	49	ATP13A4,SLC4A4,PTPRZ1
3.920e-02	-3.24	Cadherin-like_sf	interpro domains	IPR015919	116	2	18521	50	CDH20,PCDH9
3.930e-02	-3.24	BRK1 (BRICK1 subunit of SCAR/WAVE actin nucleating complex)	protein interactions	55845	122	2	19454	50	DTNA,NHSL1
3.930e-02	-3.24	MED31 (mediator complex subunit 31)	protein interactions	51003	122	2	19454	50	QKI,CPE
3.935e-02	-3.24	perinuclear region of cytoplasm	cellular component	GO:0048471	735	5	19108	49	MEIS2,PTGDS,NDRG2,SLC1A3,CLU
3.943e-02	-3.23	human chr13q31.3	chromosome location	human chr13q31.3	21	1	26134	50	GPC5
3.943e-02	-3.23	human chr4q32.3	chromosome location	human chr4q32.3	21	1	26134	50	CPE
3.954e-02	-3.23	Cadherin	pfam domains	PF00028	112	2	17795	50	CDH20,PCDH9
3.963e-02	-3.23	lung-carcinoma-squamous_cell_carcinoma	COSMIC cancer mutations	lung-carcinoma-squamous_cell_carcinoma	14664	47	16828	49	PON2,DTNA,APOE,GLI3,FGFR3,PCDH9,AMZ2,NKAIN3,ARHGAP24,CDH20,PREX2,PARD3B,MACF1,PITPNC1,GLIS3,PTPRZ1,SPON1,SLC1A3,NPAS3,MEIS2,ATP13A4,QKI,SLC4A4,NTM,CTNND2,GPC5,MAML2,ABLIM1,CLU,COL5A3,FBXL7,ACSS1,PTGDS,NHSL1,MSI2,PAMR1,GPM6A,SORBS1,NFIA,TRPS1,BMPR1B,CPE,AQP4,LSAMP,RYR3,SLC1A2,SPARCL1
3.964e-02	-3.23	exit from mitosis	biological process	GO:0010458	15	1	18204	49	NFIA
3.964e-02	-3.23	regulation of phospholipid transport	biological process	GO:2001138	15	1	18204	49	APOE
3.964e-02	-3.23	regulation of neuron projection arborization	biological process	GO:0150011	15	1	18204	49	MACF1
3.964e-02	-3.23	positive regulation of cholesterol metabolic process	biological process	GO:0090205	15	1	18204	49	APOE
3.964e-02	-3.23	positive regulation of glycogen biosynthetic process	biological process	GO:0045725	15	1	18204	49	SORBS1
3.964e-02	-3.23	chondrocyte proliferation	biological process	GO:0035988	15	1	18204	49	FGFR3
3.964e-02	-3.23	protein homotrimerization	biological process	GO:0070207	15	1	18204	49	SLC1A2
3.964e-02	-3.23	lipoprotein catabolic process	biological process	GO:0042159	15	1	18204	49	APOE
3.964e-02	-3.23	dorsal/ventral neural tube patterning	biological process	GO:0021904	15	1	18204	49	GLI3
3.964e-02	-3.23	sarcoplasmic reticulum calcium ion transport	biological process	GO:0070296	15	1	18204	49	RYR3
3.964e-02	-3.23	regulation of circadian sleep/wake cycle, sleep	biological process	GO:0045187	15	1	18204	49	PTGDS
3.964e-02	-3.23	synapse maturation	biological process	GO:0060074	15	1	18204	49	NFIA
3.964e-02	-3.23	response to caffeine	biological process	GO:0031000	15	1	18204	49	RYR3
3.975e-02	-3.23	Znf_GATA	interpro domains	IPR000679	15	1	18521	50	TRPS1
3.988e-02	-3.22	PAX7 (paired box 7)	protein interactions	5081	123	2	19454	50	TRPS1,NFIA
4.002e-02	-3.22	soft_tissue-small_round_cell_tumour	COSMIC cancer mutations	soft_tissue-small_round_cell_tumour	14	1	16828	49	FGFR3
4.002e-02	-3.22	endometriosis	COSMIC cancer mutations	endometriosis	14	1	16828	49	FGFR3
4.002e-02	-3.22	in_situ_neoplasm	COSMIC cancer mutations	in_situ_neoplasm	14	1	16828	49	FGFR3
4.002e-02	-3.22	small_round_cell_tumour	COSMIC cancer mutations	small_round_cell_tumour	14	1	16828	49	FGFR3
4.002e-02	-3.22	urinary_tract-renal_pelvis-carcinoma-transitional_cell_carcinoma	COSMIC cancer mutations	urinary_tract-renal_pelvis-carcinoma-transitional_cell_carcinoma	14	1	16828	49	FGFR3
4.010e-02	-3.22	DCC mediated attractive signaling	REACTOME pathways	R-HSA-418885	14	1	10285	30	ABLIM1
4.035e-02	-3.21	CDH12 (cadherin 12)	protein interactions	1010	16	1	19454	50	CTNNA2
4.035e-02	-3.21	CTSK (cathepsin K)	protein interactions	1513	16	1	19454	50	FGFR3
4.035e-02	-3.21	FNDC8 (fibronectin type III domain containing 8)	protein interactions	54752	16	1	19454	50	SPARCL1
4.035e-02	-3.21	HLA-H (major histocompatibility complex, class I, H (pseudogene))	protein interactions	3136	16	1	19454	50	FGFR3
4.035e-02	-3.21	SAPCD1 (suppressor APC domain containing 1)	protein interactions	401251	16	1	19454	50	CTNNA2
4.035e-02	-3.21	VGLL1 (vestigial like family member 1)	protein interactions	51442	16	1	19454	50	MEIS2
4.035e-02	-3.21	AMMECR1L (AMMECR1 like)	protein interactions	83607	16	1	19454	50	MACF1
4.035e-02	-3.21	CYP2C8 (cytochrome P450 family 2 subfamily C member 8)	protein interactions	1558	16	1	19454	50	APOE
4.035e-02	-3.21	GMPR2 (guanosine monophosphate reductase 2)	protein interactions	51292	16	1	19454	50	ARHGAP24
4.060e-02	-3.20	protein maturation	biological process	GO:0051604	483	4	18204	49	GLI3,CPE,CLU,SPON1
4.065e-02	-3.20	membrane protein complex	cellular component	GO:0098796	1261	7	19108	49	SORBS1,BMPR1B,SLC1A3,CDH20,RYR3,CTNNA2,SLC1A2
4.079e-02	-3.20	SP7 (Sp7 transcription factor)	protein interactions	121340	297	3	19454	50	NFIA,TRPS1,QKI
4.079e-02	-3.20	urinary_tract-bladder-carcinoma-transitional_cell_carcinoma	COSMIC cancer mutations	urinary_tract-bladder-carcinoma-transitional_cell_carcinoma	6040	24	16828	49	GPC5,SPARCL1,ATP13A4,SLC4A4,GLIS3,SLC1A3,PTPRZ1,MACF1,GPM6A,SORBS1,PREX2,NFIA,TRPS1,PARD3B,CDH20,COL5A3,ACSS1,PCDH9,FGFR3,GLI3,ABLIM1,CLU,DTNA,PON2
4.095e-02	-3.20	transitional_cell_carcinoma	COSMIC cancer mutations	transitional_cell_carcinoma	6042	24	16828	49	DTNA,ABLIM1,CLU,PON2,ACSS1,COL5A3,PCDH9,GLI3,FGFR3,CDH20,SORBS1,GPM6A,PREX2,TRPS1,NFIA,PARD3B,MACF1,GLIS3,SLC1A3,PTPRZ1,SLC4A4,ATP13A4,SPARCL1,GPC5
4.115e-02	-3.19	negative regulation of cellular component organization	biological process	GO:0051129	709	5	18204	49	CLU,ARHGAP24,CTNNA2,APOE,CST3
4.117e-02	-3.19	secondary active transmembrane transporter activity	molecular function	GO:0015291	289	3	18094	48	SLC1A2,SLC1A3,SLC4A4
4.118e-02	-3.19	skin-extremity-malignant_melanoma	COSMIC cancer mutations	skin-extremity-malignant_melanoma	1875	10	16828	49	ACSS1,FBXL7,COL5A3,PREX2,RYR3,PTPRZ1,PCDH9,ATP13A4,CDH20,PITPNC1
4.121e-02	-3.19	basal_(triple-negative)_carcinoma	COSMIC cancer mutations	basal_(triple-negative)_carcinoma	2981	14	16828	49	PON2,MAML2,MACF1,NDRG2,GLI3,FGFR3,BMPR1B,MSI2,NTM,ARHGAP24,SLC4A4,NPAS3,MEIS2,SPARCL1
4.121e-02	-3.19	breast-carcinoma-basal_(triple-negative)_carcinoma	COSMIC cancer mutations	breast-carcinoma-basal_(triple-negative)_carcinoma	2981	14	16828	49	MACF1,MAML2,PON2,BMPR1B,GLI3,FGFR3,NDRG2,SLC4A4,MEIS2,NPAS3,MSI2,ARHGAP24,NTM,SPARCL1
4.126e-02	-3.19	cell junction assembly	biological process	GO:0034329	285	3	18204	49	CDH20,GPM6A,SORBS1
4.127e-02	-3.19	human chr3q13.31	chromosome location	human chr3q13.31	22	1	26134	50	LSAMP
4.144e-02	-3.18	striated muscle contraction	biological process	GO:0006941	120	2	18204	49	DTNA,RYR3
4.156e-02	-3.18	cellular component organization or biogenesis	biological process	GO:0071840	5850	22	18204	49	GLI3,ABLIM1,CTNNA2,SPARCL1,RYR3,SORBS1,GPM6A,PARD3B,NFIA,PREX2,AQP4,SLC1A2,BMPR1B,PTPRZ1,CDH20,MACF1,CTNND2,APOE,PITPNC1,CST3,CLU,COL5A3
4.163e-02	-3.18	water channel activity	molecular function	GO:0015250	16	1	18094	48	AQP4
4.163e-02	-3.18	misfolded protein binding	molecular function	GO:0051787	16	1	18094	48	CLU
4.166e-02	-3.18	SYP (synaptophysin)	protein interactions	6855	126	2	19454	50	GPM6A,PITPNC1
4.166e-02	-3.18	RNF115 (ring finger protein 115)	protein interactions	27246	126	2	19454	50	NDRG2,CST3
4.176e-02	-3.18	Glycerol uptake facilitator protein	gene3d domains	1.20.1080.10	14	1	14470	44	AQP4
4.198e-02	-3.17	ossification	biological process	GO:0001503	287	3	18204	49	BMPR1B,GLI3,FGFR3
4.223e-02	-3.16	insulin metabolic process	biological process	GO:1901142	16	1	18204	49	CPE
4.223e-02	-3.16	locomotory exploration behavior	biological process	GO:0035641	16	1	18204	49	APOE
4.223e-02	-3.16	nonribosomal peptide biosynthetic process	biological process	GO:0019184	16	1	18204	49	SLC1A2
4.223e-02	-3.16	nose development	biological process	GO:0043584	16	1	18204	49	GLI3
4.223e-02	-3.16	positive regulation of membrane protein ectodomain proteolysis	biological process	GO:0051044	16	1	18204	49	APOE
4.223e-02	-3.16	low-density lipoprotein particle remodeling	biological process	GO:0034374	16	1	18204	49	APOE
4.223e-02	-3.16	non-proteinogenic amino acid biosynthetic process	biological process	GO:0170043	16	1	18204	49	SLC1A3
4.223e-02	-3.16	spinal cord dorsal/ventral patterning	biological process	GO:0021513	16	1	18204	49	GLI3
4.223e-02	-3.16	cardiac left ventricle morphogenesis	biological process	GO:0003214	16	1	18204	49	CPE
4.223e-02	-3.16	wound healing, spreading of epidermal cells	biological process	GO:0035313	16	1	18204	49	ARHGAP24
4.223e-02	-3.16	short-chain fatty acid metabolic process	biological process	GO:0046459	16	1	18204	49	ACSS1
4.235e-02	-3.16	CarboxyPept-like_regulatory	interpro domains	IPR008969	16	1	18521	50	CPE
4.240e-02	-3.16	DWA	smart domains	SM00523	12	1	9717	35	NFIA
4.240e-02	-3.16	ZnF_GATA	smart domains	SM00401	12	1	9717	35	TRPS1
4.273e-02	-3.15	apical dendrite	cellular component	GO:0097440	17	1	19108	49	CLU
4.282e-02	-3.15	ureter	COSMIC cancer mutations	ureter	15	1	16828	49	FGFR3
4.282e-02	-3.15	hypothalamus	COSMIC cancer mutations	hypothalamus	15	1	16828	49	QKI
4.282e-02	-3.15	Pef1 (penta-EF hand domain containing 1)	protein interactions	67898	17	1	19454	50	QKI
4.282e-02	-3.15	RASL12 (RAS like family 12)	protein interactions	51285	17	1	19454	50	BMPR1B
4.282e-02	-3.15	TAGAP (T cell activation RhoGTPase activating protein)	protein interactions	117289	17	1	19454	50	DTNA
4.282e-02	-3.15	Shcbp1 (Shc SH2-domain binding protein 1)	protein interactions	20419	17	1	19454	50	GPC5
4.282e-02	-3.15	DPP6 (dipeptidyl peptidase like 6)	protein interactions	1804	17	1	19454	50	GPM6A
4.282e-02	-3.15	SEPSECS (Sep (O-phosphoserine) tRNA:Sec (selenocysteine) tRNA synthase)	protein interactions	51091	17	1	19454	50	ABLIM1
4.282e-02	-3.15	ZNF557 (zinc finger protein 557)	protein interactions	79230	17	1	19454	50	ARHGAP24
4.282e-02	-3.15	Sqstm1 (sequestosome 1)	protein interactions	18412	17	1	19454	50	BMPR1B
4.282e-02	-3.15	C16orf92 (chromosome 16 open reading frame 92)	protein interactions	146378	17	1	19454	50	APOE
4.282e-02	-3.15	NOTCH4 (notch receptor 4)	protein interactions	4855	17	1	19454	50	MAML2
4.282e-02	-3.15	PAX4 (paired box 4)	protein interactions	5078	17	1	19454	50	NTM
4.286e-02	-3.15	MYB (MYB proto-oncogene, transcription factor)	protein interactions	4602	128	2	19454	50	NFIA,TRPS1
4.290e-02	-3.15	Synthesis of Prostaglandins (PG) and Thromboxanes (TX)	REACTOME pathways	R-HSA-2162123	15	1	10285	30	PTGDS
4.346e-02	-3.14	POLA2 (DNA polymerase alpha 2, accessory subunit)	protein interactions	23649	129	2	19454	50	FGFR3,CPE
4.362e-02	-3.13	bone-extraskeletal-Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour	COSMIC cancer mutations	bone-extraskeletal-Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour	891	6	16828	49	FGFR3,PTPRZ1,SPARCL1,NPAS3,ABLIM1,PTGDS
4.367e-02	-3.13	monoatomic ion transport	biological process	GO:0006811	964	6	18204	49	SLC4A4,SLC1A2,ATP13A4,RYR3,GPM6A,SLC1A3
4.389e-02	-3.13	actin cytoskeleton	cellular component	GO:0015629	520	4	19108	49	CTNNA2,MACF1,SORBS1,ABLIM1
4.391e-02	-3.13	CARBOXYPEPT_ZN_2	prosite domains	PS00133	13	1	12186	42	CPE
4.391e-02	-3.13	CARBOXYPEPT_ZN_1	prosite domains	PS00132	13	1	12186	42	CPE
4.397e-02	-3.12	positive regulation of lipid metabolic process	biological process	GO:0045834	124	2	18204	49	SORBS1,APOE
4.400e-02	-3.12	basal part of cell	cellular component	GO:0045178	307	3	19108	49	SLC4A4,SLC1A3,AQP4
4.415e-02	-3.12	establishment of localization	biological process	GO:0051234	3887	16	18204	49	GLI3,PARD3B,GPM6A,RYR3,AQP4,SLC4A4,QKI,SLC1A2,CPE,ATP13A4,PITPNC1,APOE,MACF1,SLC1A3,PTGDS,CLU
4.417e-02	-3.12	transmembrane receptor protein tyrosine phosphatase activity	molecular function	GO:0005001	17	1	18094	48	PTPRZ1
4.417e-02	-3.12	transmembrane receptor protein phosphatase activity	molecular function	GO:0019198	17	1	18094	48	PTPRZ1
4.472e-02	-3.11	middle_lobe	COSMIC cancer mutations	middle_lobe	1382	8	16828	49	MACF1,ATP13A4,CPE,CTNND2,RYR3,FGFR3,PARD3B,PCDH9
4.481e-02	-3.11	cell population proliferation	biological process	GO:0008283	726	5	18204	49	GLI3,NDRG2,NFIA,FGFR3,CLU
4.481e-02	-3.11	embryonic digestive tract morphogenesis	biological process	GO:0048557	17	1	18204	49	GLI3
4.481e-02	-3.11	specification of animal organ identity	biological process	GO:0010092	17	1	18204	49	GLI3
4.481e-02	-3.11	high-density lipoprotein particle remodeling	biological process	GO:0034375	17	1	18204	49	APOE
4.481e-02	-3.11	positive regulation of vascular permeability	biological process	GO:0043117	17	1	18204	49	APOE
4.481e-02	-3.11	negative regulation of triglyceride metabolic process	biological process	GO:0090209	17	1	18204	49	APOE
4.481e-02	-3.11	positive regulation of glycogen metabolic process	biological process	GO:0070875	17	1	18204	49	SORBS1
4.481e-02	-3.11	viral genome replication	biological process	GO:0019079	17	1	18204	49	NFIA
4.481e-02	-3.11	cell migration in hindbrain	biological process	GO:0021535	17	1	18204	49	CTNNA2
4.481e-02	-3.11	fatty acid homeostasis	biological process	GO:0055089	17	1	18204	49	APOE
4.481e-02	-3.11	protein trimerization	biological process	GO:0070206	17	1	18204	49	SLC1A2
4.481e-02	-3.11	regulation of inclusion body assembly	biological process	GO:0090083	17	1	18204	49	CLU
4.481e-02	-3.11	ureter development	biological process	GO:0072189	17	1	18204	49	NFIA
4.481e-02	-3.11	cellular response to ATP	biological process	GO:0071318	17	1	18204	49	RYR3
4.493e-02	-3.10	regulation of ERK1 and ERK2 cascade	biological process	GO:0070372	295	3	18204	49	APOE,NDRG2,FGFR3
4.493e-02	-3.10	AMP-bd_C	interpro domains	IPR025110	17	1	18521	50	ACSS1
4.493e-02	-3.10	CA_dom_sf	interpro domains	IPR036398	17	1	18521	50	PTPRZ1
4.493e-02	-3.10	CA_dom	interpro domains	IPR001148	17	1	18521	50	PTPRZ1
4.493e-02	-3.10	Cystatin_dom	interpro domains	IPR000010	17	1	18521	50	CST3
4.499e-02	-3.10	AFDN (afadin, adherens junction formation factor)	protein interactions	4301	309	3	19454	50	SORBS1,DTNA,MACF1
4.525e-02	-3.10	positive regulation of cellular biosynthetic process	biological process	GO:0031328	2652	12	18204	49	APOE,CLU,NPAS3,MEIS2,SORBS1,SPON1,GLI3,MAML2,BMPR1B,NFIA,QKI,GLIS3
4.529e-02	-3.09	Tgfbr1 (transforming growth factor, beta receptor I)	protein interactions	21812	18	1	19454	50	BMPR1B
4.529e-02	-3.09	OPCML (opioid binding protein/cell adhesion molecule like)	protein interactions	4978	18	1	19454	50	NTM
4.529e-02	-3.09	ZNF100 (zinc finger protein 100)	protein interactions	163227	18	1	19454	50	ARHGAP24
4.529e-02	-3.09	NKIRAS1 (NFKB inhibitor interacting Ras like 1)	protein interactions	28512	18	1	19454	50	BMPR1B
4.529e-02	-3.09	NECTIN1 (nectin cell adhesion molecule 1)	protein interactions	5818	18	1	19454	50	FGFR3
4.529e-02	-3.09	TTC29 (tetratricopeptide repeat domain 29)	protein interactions	83894	18	1	19454	50	MACF1
4.529e-02	-3.09	KLHL1 (kelch like family member 1)	protein interactions	57626	18	1	19454	50	BMPR1B
4.529e-02	-3.09	Lck (lymphocyte protein tyrosine kinase)	protein interactions	16818	18	1	19454	50	APOE
4.529e-02	-3.09	AK9 (adenylate kinase 9)	protein interactions	221264	18	1	19454	50	ARHGAP24
4.529e-02	-3.09	Cnot2 (CCR4-NOT transcription complex, subunit 2)	protein interactions	72068	18	1	19454	50	MACF1
4.529e-02	-3.09	PTGFR (prostaglandin F receptor)	protein interactions	5737	18	1	19454	50	PTGDS
4.529e-02	-3.09	CYP2E1 (cytochrome P450 family 2 subfamily E member 1)	protein interactions	1571	18	1	19454	50	CLU
4.530e-02	-3.09	GPIHBP1 (glycosylphosphatidylinositol anchored high density lipoprotein binding protein 1)	protein interactions	338328	132	2	19454	50	CPE,FGFR3
4.535e-02	-3.09	C11orf52 (chromosome 11 open reading frame 52)	protein interactions	91894	310	3	19454	50	DTNA,ABLIM1,MACF1
4.557e-02	-3.09	cytoskeletal protein binding	molecular function	GO:0008092	989	6	18094	48	CLU,APOE,CTNNA2,ABLIM1,SORBS1,MACF1
4.561e-02	-3.09	normal	COSMIC cancer mutations	normal	16	1	16828	49	FGFR3
4.561e-02	-3.09	urinary_tract-carcinoma	COSMIC cancer mutations	urinary_tract-carcinoma	16	1	16828	49	FGFR3
4.561e-02	-3.09	flank	COSMIC cancer mutations	flank	16	1	16828	49	FGFR3
4.561e-02	-3.09	renal_pelvis	COSMIC cancer mutations	renal_pelvis	16	1	16828	49	FGFR3
4.569e-02	-3.09	carboxylic acid transport	biological process	GO:0046942	297	3	18204	49	SLC1A3,APOE,SLC1A2
4.606e-02	-3.08	extraskeletal	COSMIC cancer mutations	extraskeletal	903	6	16828	49	ABLIM1,PTGDS,NPAS3,SPARCL1,FGFR3,PTPRZ1
4.607e-02	-3.08	organic acid transport	biological process	GO:0015849	298	3	18204	49	APOE,SLC1A2,SLC1A3
4.613e-02	-3.08	PDZ	pfam domains	PF00595	122	2	17795	50	PARD3B,PREX2
4.649e-02	-3.07	MFAP5-mediated ovarian cancer cell motility and invasiveness	WikiPathways	WP3301	12	1	5310	21	RYR3
4.649e-02	-3.07	Bone Morphogenic Protein (BMP) Signalling and Regulation	WikiPathways	WP1425	12	1	5310	21	BMPR1B
4.652e-02	-3.07	cellular response to organonitrogen compound	biological process	GO:0071417	505	4	18204	49	RYR3,SORBS1,SLC1A2,SLC1A3
4.655e-02	-3.07	myelination	biological process	GO:0042552	128	2	18204	49	QKI,CLU
4.671e-02	-3.06	intracellularly gated calcium channel activity	molecular function	GO:0015278	18	1	18094	48	RYR3
4.671e-02	-3.06	phosphatidylcholine transporter activity	molecular function	GO:0008525	18	1	18094	48	PITPNC1
4.671e-02	-3.06	heparan sulfate proteoglycan binding	molecular function	GO:0043395	18	1	18094	48	APOE
4.673e-02	-3.06	ZZ	pfam domains	PF00569	17	1	17795	50	DTNA
4.673e-02	-3.06	AMP-binding_C	pfam domains	PF13193	17	1	17795	50	ACSS1
4.673e-02	-3.06	Carb_anhydrase	pfam domains	PF00194	17	1	17795	50	PTPRZ1
4.673e-02	-3.06	Cystatin	pfam domains	PF00031	17	1	17795	50	CST3
4.674e-02	-3.06	GRB2 (growth factor receptor bound protein 2)	protein interactions	2885	769	5	19454	50	SLC1A2,MSI2,CLU,PON2,FGFR3
4.696e-02	-3.06	Cadherins	gene3d domains	2.60.40.60	114	2	14470	44	PCDH9,CDH20
4.716e-02	-3.05	NTRK2 (neurotrophic receptor tyrosine kinase 2)	protein interactions	4915	135	2	19454	50	ABLIM1,DTNA
4.716e-02	-3.05	BMP4 (bone morphogenetic protein 4)	protein interactions	652	135	2	19454	50	CLU,BMPR1B
4.716e-02	-3.05	SOX15 (SRY-box transcription factor 15)	protein interactions	6665	135	2	19454	50	TRPS1,NFIA
4.716e-02	-3.05	Myo1c (myosin IC)	protein interactions	17913	135	2	19454	50	TRPS1,ABLIM1
4.718e-02	-3.05	Glutamatergic synapse	KEGG pathways	hsa04724	114	2	7161	22	SLC1A2,SLC1A3
4.718e-02	-3.05	Glutamatergic synapse	KEGG pathways	ko04724	114	2	7161	22	SLC1A3,SLC1A2
4.721e-02	-3.05	regulation of cell population proliferation	biological process	GO:0042127	1790	9	18204	49	CLU,FGFR3,NDRG2,BMPR1B,PTPRZ1,GLI3,PTGDS,APOE,MEIS2
4.722e-02	-3.05	central_nervous_system-brain-glioma-astrocytoma_Grade_IV	COSMIC cancer mutations	central_nervous_system-brain-glioma-astrocytoma_Grade_IV	15813	49	16828	49	PREX2,PARD3B,CDH20,ARHGAP24,AMZ2,NKAIN3,PCDH9,GLI3,FGFR3,DTNA,PON2,APOE,CTNND2,GPC5,SLC4A4,ATP13A4,QKI,NPAS3,MEIS2,NTM,GLIS3,SLC1A3,SPON1,NDRG2,PTPRZ1,MACF1,PITPNC1,SORBS1,GPM6A,TRPS1,NFIA,PTGDS,PAMR1,MSI2,NHSL1,ACSS1,FBXL7,COL5A3,CST3,CLU,ABLIM1,MAML2,SLC1A2,RYR3,LSAMP,SPARCL1,AQP4,CPE,BMPR1B
4.737e-02	-3.05	circulatory system process	biological process	GO:0003013	508	4	18204	49	SLC4A4,SLC1A3,APOE,SLC1A2
4.738e-02	-3.05	myelin maintenance	biological process	GO:0043217	18	1	18204	49	CLU
4.738e-02	-3.05	dendritic spine morphogenesis	biological process	GO:0060997	18	1	18204	49	CTNND2
4.738e-02	-3.05	negative regulation of platelet activation	biological process	GO:0010544	18	1	18204	49	APOE
4.738e-02	-3.05	spinal cord patterning	biological process	GO:0021511	18	1	18204	49	GLI3
4.738e-02	-3.05	response to misfolded protein	biological process	GO:0051788	18	1	18204	49	CLU
4.738e-02	-3.05	regulation of extracellular matrix disassembly	biological process	GO:0010715	18	1	18204	49	CST3
4.752e-02	-3.05	ATPase_P-typ_cation-transptr_N	interpro domains	IPR004014	18	1	18521	50	ATP13A4
4.752e-02	-3.05	Leu-rich_rpt_Cys-con_subtyp	interpro domains	IPR006553	18	1	18521	50	FBXL7
4.754e-02	-3.05	ZYX (zyxin)	protein interactions	7791	316	3	19454	50	MACF1,ABLIM1,SORBS1
4.764e-02	-3.04	parallel fiber to Purkinje cell synapse	cellular component	GO:0098688	19	1	19108	49	GPM6A
4.774e-02	-3.04	CCL14 (C-C motif chemokine ligand 14)	protein interactions	6358	19	1	19454	50	AMZ2
4.774e-02	-3.04	SPZ1 (spermatogenic leucine zipper 1)	protein interactions	84654	19	1	19454	50	DTNA
4.774e-02	-3.04	FBXO27 (F-box protein 27)	protein interactions	126433	19	1	19454	50	CLU
4.774e-02	-3.04	CNTNAP4 (contactin associated protein family member 4)	protein interactions	85445	19	1	19454	50	MACF1
4.774e-02	-3.04	TNR (tenascin R)	protein interactions	7143	19	1	19454	50	PTPRZ1
4.774e-02	-3.04	PHYHIPL (phytanoyl-CoA 2-hydroxylase interacting protein like)	protein interactions	84457	19	1	19454	50	GPM6A
4.774e-02	-3.04	ZNF138 (zinc finger protein 138)	protein interactions	7697	19	1	19454	50	ARHGAP24
4.786e-02	-3.04	ensheathment of neurons	biological process	GO:0007272	130	2	18204	49	CLU,QKI
4.786e-02	-3.04	axon ensheathment	biological process	GO:0008366	130	2	18204	49	CLU,QKI
4.804e-02	-3.04	acute_lymphoblastic_leukaemia	COSMIC cancer mutations	acute_lymphoblastic_leukaemia	2197	11	16828	49	ARHGAP24,DTNA,SLC4A4,PTPRZ1,PARD3B,GLI3,FGFR3,TRPS1,NFIA,PREX2,BMPR1B
4.839e-02	-3.03	skin-other-verrucal_keratosis_BRAF_inhibitor_related	COSMIC cancer mutations	skin-other-verrucal_keratosis_BRAF_inhibitor_related	17	1	16828	49	FGFR3
4.839e-02	-3.03	central_nervous_system-optic_nerve-glioma-astrocytoma_Grade_I	COSMIC cancer mutations	central_nervous_system-optic_nerve-glioma-astrocytoma_Grade_I	17	1	16828	49	QKI
4.839e-02	-3.03	optic_nerve	COSMIC cancer mutations	optic_nerve	17	1	16828	49	QKI
4.839e-02	-3.03	breast-carcinoma-neuroendocrine_carcinoma	COSMIC cancer mutations	breast-carcinoma-neuroendocrine_carcinoma	17	1	16828	49	FGFR3
4.839e-02	-3.03	non_chronically_sun_exposed_site	COSMIC cancer mutations	non_chronically_sun_exposed_site	17	1	16828	49	FGFR3
4.839e-02	-3.03	skin-carcinoma-squamous_cell_carcinoma_BRAF_inhibitor_related	COSMIC cancer mutations	skin-carcinoma-squamous_cell_carcinoma_BRAF_inhibitor_related	17	1	16828	49	FGFR3
4.839e-02	-3.03	squamous_cell_carcinoma_BRAF_inhibitor_related	COSMIC cancer mutations	squamous_cell_carcinoma_BRAF_inhibitor_related	17	1	16828	49	FGFR3
4.839e-02	-3.03	skin-non_chronically_sun_exposed_site-malignant_melanoma	COSMIC cancer mutations	skin-non_chronically_sun_exposed_site-malignant_melanoma	17	1	16828	49	FGFR3
4.839e-02	-3.03	verrucal_keratosis_BRAF_inhibitor_related	COSMIC cancer mutations	verrucal_keratosis_BRAF_inhibitor_related	17	1	16828	49	FGFR3
4.852e-02	-3.03	carboxylic acid transmembrane transport	biological process	GO:1905039	131	2	18204	49	SLC1A3,SLC1A2
4.859e-02	-3.02	human chr18q12.1	chromosome location	human chr18q12.1	26	1	26134	50	DTNA
4.879e-02	-3.02	transport	biological process	GO:0006810	3615	15	18204	49	CLU,MACF1,PITPNC1,APOE,PTGDS,SLC1A3,ATP13A4,CPE,SLC1A2,QKI,SLC4A4,AQP4,RYR3,GPM6A,GLI3
4.893e-02	-3.02	kidney-other-neoplasm	COSMIC cancer mutations	kidney-other-neoplasm	10653	37	16828	49	MACF1,SPON1,SLC1A3,PTPRZ1,QKI,ATP13A4,AQP4,CPE,MEIS2,NPAS3,RYR3,CTNND2,SLC1A2,LSAMP,GPC5,SPARCL1,ABLIM1,CLU,DTNA,MAML2,PON2,COL5A3,ACSS1,FBXL7,PCDH9,NKAIN3,AMZ2,FGFR3,GLI3,NHSL1,PAMR1,CDH20,ARHGAP24,GPM6A,SORBS1,PREX2,TRPS1
4.905e-02	-3.01	NFIB (nuclear factor I B)	protein interactions	4781	138	2	19454	50	NFIA,TRPS1
4.916e-02	-3.01	regulation of small GTPase mediated signal transduction	biological process	GO:0051056	306	3	18204	49	ARHGAP24,PREX2,APOE
4.918e-02	-3.01	amino acid transport	biological process	GO:0006865	132	2	18204	49	SLC1A3,SLC1A2
4.924e-02	-3.01	transmembrane receptor protein serine/threonine kinase activity	molecular function	GO:0004675	19	1	18094	48	BMPR1B
4.924e-02	-3.01	water transmembrane transporter activity	molecular function	GO:0005372	19	1	18094	48	AQP4
4.931e-02	-3.01	TRIM67 (tripartite motif containing 67)	protein interactions	440730	4804	18	19454	50	APOE,CTNNA2,SLC4A4,CLU,CST3,QKI,SLC1A3,MACF1,DTNA,CTNND2,GPM6A,MSI2,LSAMP,PON2,NTM,PTPRZ1,PITPNC1,ACSS1
4.940e-02	-3.01	ACTA1 (actin alpha 1, skeletal muscle)	protein interactions	58	321	3	19454	50	DTNA,MACF1,SORBS1
4.941e-02	-3.01	Cation_ATPase_N	pfam domains	PF00690	18	1	17795	50	ATP13A4
4.962e-02	-3.00	thalamus	COSMIC cancer mutations	thalamus	284	3	16828	49	QKI,DTNA,FGFR3
4.968e-02	-3.00	DUSP22 (dual specificity phosphatase 22)	protein interactions	56940	139	2	19454	50	QKI,CTNNA2
4.995e-02	-3.00	negative regulation of alcohol biosynthetic process	biological process	GO:1902931	19	1	18204	49	APOE
4.995e-02	-3.00	craniofacial suture morphogenesis	biological process	GO:0097094	19	1	18204	49	GLI3
4.995e-02	-3.00	regulation of circadian sleep/wake cycle	biological process	GO:0042749	19	1	18204	49	PTGDS
4.995e-02	-3.00	vocalization behavior	biological process	GO:0071625	19	1	18204	49	GLI3
4.995e-02	-3.00	cartilage condensation	biological process	GO:0001502	19	1	18204	49	BMPR1B
4.995e-02	-3.00	vascular associated smooth muscle cell differentiation	biological process	GO:0035886	19	1	18204	49	QKI